id	sid	tid	token	lemma	pos
cord-011327-zsoc4wec	1	1	key	key	JJ
cord-011327-zsoc4wec	2	1	:	:	:
cord-011327-zsoc4wec	2	2	cord-011327-zsoc4wec	cord-011327-zsoc4wec	NN
cord-011327-zsoc4wec	2	3	authors	author	NNS
cord-011327-zsoc4wec	2	4	:	:	:
cord-011327-zsoc4wec	2	5	Martin	Martin	NNP
cord-011327-zsoc4wec	2	6	-	-	HYPH
cord-011327-zsoc4wec	2	7	Loeches	Loeches	NNP
cord-011327-zsoc4wec	2	8	,	,	,
cord-011327-zsoc4wec	2	9	Ignacio	Ignacio	NNP
cord-011327-zsoc4wec	2	10	;	;	:
cord-011327-zsoc4wec	2	11	Leone	Leone	NNP
cord-011327-zsoc4wec	2	12	,	,	,
cord-011327-zsoc4wec	2	13	Marc	Marc	NNP
cord-011327-zsoc4wec	2	14	;	;	:
cord-011327-zsoc4wec	2	15	Einav	Einav	NNP
cord-011327-zsoc4wec	2	16	,	,	,
cord-011327-zsoc4wec	3	1	Sharon	Sharon	NNP
cord-011327-zsoc4wec	3	2	title	title	NN
cord-011327-zsoc4wec	3	3	:	:	:
cord-011327-zsoc4wec	3	4	Antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	3	5	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	3	6	in	in	IN
cord-011327-zsoc4wec	3	7	the	the	DT
cord-011327-zsoc4wec	3	8	ICU	ICU	NNP
cord-011327-zsoc4wec	3	9	:	:	:
cord-011327-zsoc4wec	3	10	to	to	TO
cord-011327-zsoc4wec	3	11	be	be	VB
cord-011327-zsoc4wec	3	12	or	or	CC
cord-011327-zsoc4wec	3	13	not	not	RB
cord-011327-zsoc4wec	3	14	to	to	TO
cord-011327-zsoc4wec	3	15	be	be	VB
cord-011327-zsoc4wec	3	16	administered	administer	VBN
cord-011327-zsoc4wec	3	17	for	for	IN
cord-011327-zsoc4wec	3	18	patients	patient	NNS
cord-011327-zsoc4wec	3	19	undergoing	undergo	VBG
cord-011327-zsoc4wec	3	20	procedures	procedure	NNS
cord-011327-zsoc4wec	3	21	?	?	.
cord-011327-zsoc4wec	4	1	date	date	NN
cord-011327-zsoc4wec	4	2	:	:	:
cord-011327-zsoc4wec	4	3	2019	2019	CD
cord-011327-zsoc4wec	4	4	-	-	HYPH
cord-011327-zsoc4wec	4	5	11	11	CD
cord-011327-zsoc4wec	4	6	-	-	SYM
cord-011327-zsoc4wec	4	7	28	28	CD
cord-011327-zsoc4wec	4	8	journal	journal	NN
cord-011327-zsoc4wec	4	9	:	:	:
cord-011327-zsoc4wec	5	1	Intensive	intensive	JJ
cord-011327-zsoc4wec	5	2	Care	care	NN
cord-011327-zsoc4wec	5	3	Med	Med	NNP
cord-011327-zsoc4wec	5	4	DOI	doi	NN
cord-011327-zsoc4wec	5	5	:	:	:
cord-011327-zsoc4wec	5	6	10.1007	10.1007	CD
cord-011327-zsoc4wec	5	7	/	/	SYM
cord-011327-zsoc4wec	5	8	s00134	s00134	VBN
cord-011327-zsoc4wec	5	9	-	-	HYPH
cord-011327-zsoc4wec	5	10	019	019	CD
cord-011327-zsoc4wec	5	11	-	-	HYPH
cord-011327-zsoc4wec	5	12	05870	05870	CD
cord-011327-zsoc4wec	5	13	-	-	SYM
cord-011327-zsoc4wec	5	14	0	0	CD
cord-011327-zsoc4wec	5	15	sha	sha	NN
cord-011327-zsoc4wec	5	16	:	:	:
cord-011327-zsoc4wec	5	17	e871f1a62b481f78324c8a77715ee30b196d4d13	e871f1a62b481f78324c8a77715ee30b196d4d13	NNP
cord-011327-zsoc4wec	5	18	doc_id	doc_id	NNP
cord-011327-zsoc4wec	5	19	:	:	:
cord-011327-zsoc4wec	5	20	11327	11327	CD
cord-011327-zsoc4wec	5	21	cord_uid	cord_uid	NNS
cord-011327-zsoc4wec	5	22	:	:	:
cord-011327-zsoc4wec	5	23	zsoc4wec	zsoc4wec	ADD
cord-011327-zsoc4wec	6	1	nan	nan	NNP
cord-011327-zsoc4wec	6	2	Definition	Definition	NNP
cord-011327-zsoc4wec	6	3	:	:	:
cord-011327-zsoc4wec	7	1	The	the	DT
cord-011327-zsoc4wec	7	2	expression	expression	NN
cord-011327-zsoc4wec	7	3	"	"	``
cord-011327-zsoc4wec	7	4	prophylactic	prophylactic	JJ
cord-011327-zsoc4wec	7	5	"	"	''
cord-011327-zsoc4wec	7	6	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	7	7	therapy	therapy	NN
cord-011327-zsoc4wec	7	8	has	have	VBZ
cord-011327-zsoc4wec	7	9	multiple	multiple	JJ
cord-011327-zsoc4wec	7	10	uses	use	NNS
cord-011327-zsoc4wec	7	11	in	in	IN
cord-011327-zsoc4wec	7	12	the	the	DT
cord-011327-zsoc4wec	7	13	context	context	NN
cord-011327-zsoc4wec	7	14	of	of	IN
cord-011327-zsoc4wec	7	15	intensive	intensive	JJ
cord-011327-zsoc4wec	7	16	care	care	NN
cord-011327-zsoc4wec	7	17	(	(	-LRB-
cord-011327-zsoc4wec	7	18	Supplement	Supplement	NNP
cord-011327-zsoc4wec	7	19	B	B	NNP
cord-011327-zsoc4wec	7	20	)	)	-RRB-
cord-011327-zsoc4wec	8	1	[	[	-LRB-
cord-011327-zsoc4wec	8	2	9	9	CD
cord-011327-zsoc4wec	8	3	]	]	-RRB-
cord-011327-zsoc4wec	8	4	.	.	.
cord-011327-zsoc4wec	9	1	There	there	EX
cord-011327-zsoc4wec	9	2	is	be	VBZ
cord-011327-zsoc4wec	9	3	also	also	RB
cord-011327-zsoc4wec	9	4	significant	significant	JJ
cord-011327-zsoc4wec	9	5	overlap	overlap	NN
cord-011327-zsoc4wec	9	6	in	in	IN
cord-011327-zsoc4wec	9	7	the	the	DT
cord-011327-zsoc4wec	9	8	use	use	NN
cord-011327-zsoc4wec	9	9	of	of	IN
cord-011327-zsoc4wec	9	10	"	"	``
cord-011327-zsoc4wec	9	11	prophylactic	prophylactic	JJ
cord-011327-zsoc4wec	9	12	"	"	''
cord-011327-zsoc4wec	9	13	and	and	CC
cord-011327-zsoc4wec	9	14	"	"	``
cord-011327-zsoc4wec	9	15	pre	pre	JJ
cord-011327-zsoc4wec	9	16	-	-	JJ
cord-011327-zsoc4wec	9	17	emptive	emptive	JJ
cord-011327-zsoc4wec	9	18	"	"	''
cord-011327-zsoc4wec	9	19	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	9	20	administration	administration	NN
cord-011327-zsoc4wec	9	21	in	in	IN
cord-011327-zsoc4wec	9	22	the	the	DT
cord-011327-zsoc4wec	9	23	literature	literature	NN
cord-011327-zsoc4wec	9	24	[	[	-LRB-
cord-011327-zsoc4wec	9	25	10	10	CD
cord-011327-zsoc4wec	9	26	]	]	-RRB-
cord-011327-zsoc4wec	9	27	.	.	.
cord-011327-zsoc4wec	10	1	Prophylactic	prophylactic	JJ
cord-011327-zsoc4wec	10	2	therapy	therapy	NN
cord-011327-zsoc4wec	10	3	usually	usually	RB
cord-011327-zsoc4wec	10	4	entails	entail	VBZ
cord-011327-zsoc4wec	10	5	administration	administration	NN
cord-011327-zsoc4wec	10	6	of	of	IN
cord-011327-zsoc4wec	10	7	a	a	DT
cord-011327-zsoc4wec	10	8	single	single	JJ
cord-011327-zsoc4wec	10	9	dose	dose	NN
cord-011327-zsoc4wec	10	10	or	or	CC
cord-011327-zsoc4wec	10	11	,	,	,
cord-011327-zsoc4wec	10	12	at	at	IN
cord-011327-zsoc4wec	10	13	most	most	JJS
cord-011327-zsoc4wec	10	14	,	,	,
cord-011327-zsoc4wec	10	15	a	a	DT
cord-011327-zsoc4wec	10	16	day	day	NN
cord-011327-zsoc4wec	10	17	of	of	IN
cord-011327-zsoc4wec	10	18	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	10	19	treatment	treatment	NN
cord-011327-zsoc4wec	10	20	for	for	IN
cord-011327-zsoc4wec	10	21	prevention	prevention	NN
cord-011327-zsoc4wec	10	22	of	of	IN
cord-011327-zsoc4wec	10	23	infection	infection	NN
cord-011327-zsoc4wec	10	24	when	when	WRB
cord-011327-zsoc4wec	10	25	there	there	EX
cord-011327-zsoc4wec	10	26	is	be	VBZ
cord-011327-zsoc4wec	10	27	no	no	DT
cord-011327-zsoc4wec	10	28	evidence	evidence	NN
cord-011327-zsoc4wec	10	29	or	or	CC
cord-011327-zsoc4wec	10	30	suspicion	suspicion	NN
cord-011327-zsoc4wec	10	31	of	of	IN
cord-011327-zsoc4wec	10	32	infection	infection	NN
cord-011327-zsoc4wec	10	33	already	already	RB
cord-011327-zsoc4wec	10	34	being	be	VBG
cord-011327-zsoc4wec	10	35	present	present	JJ
cord-011327-zsoc4wec	10	36	[	[	-LRB-
cord-011327-zsoc4wec	10	37	4	4	CD
cord-011327-zsoc4wec	10	38	]	]	-RRB-
cord-011327-zsoc4wec	10	39	.	.	.
cord-011327-zsoc4wec	11	1	There	there	EX
cord-011327-zsoc4wec	11	2	is	be	VBZ
cord-011327-zsoc4wec	11	3	also	also	RB
cord-011327-zsoc4wec	11	4	little	little	JJ
cord-011327-zsoc4wec	11	5	-	-	HYPH
cord-011327-zsoc4wec	11	6	to	to	IN
cord-011327-zsoc4wec	11	7	-	-	HYPH
cord-011327-zsoc4wec	11	8	no	no	DT
cord-011327-zsoc4wec	11	9	literature	literature	NN
cord-011327-zsoc4wec	11	10	on	on	IN
cord-011327-zsoc4wec	11	11	the	the	DT
cord-011327-zsoc4wec	11	12	ideal	ideal	JJ
cord-011327-zsoc4wec	11	13	time	time	NN
cord-011327-zsoc4wec	11	14	for	for	IN
cord-011327-zsoc4wec	11	15	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	11	16	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	11	17	;	;	:
cord-011327-zsoc4wec	11	18	this	this	DT
cord-011327-zsoc4wec	11	19	time	time	NN
cord-011327-zsoc4wec	11	20	frame	frame	NN
cord-011327-zsoc4wec	11	21	may	may	MD
cord-011327-zsoc4wec	11	22	eventually	eventually	RB
cord-011327-zsoc4wec	11	23	vary	vary	VB
cord-011327-zsoc4wec	11	24	depending	depend	VBG
cord-011327-zsoc4wec	11	25	on	on	IN
cord-011327-zsoc4wec	11	26	patient	patient	JJ
cord-011327-zsoc4wec	11	27	and	and	CC
cord-011327-zsoc4wec	11	28	environmental	environmental	JJ
cord-011327-zsoc4wec	11	29	conditions	condition	NNS
cord-011327-zsoc4wec	11	30	and	and	CC
cord-011327-zsoc4wec	11	31	the	the	DT
cord-011327-zsoc4wec	11	32	type	type	NN
cord-011327-zsoc4wec	11	33	of	of	IN
cord-011327-zsoc4wec	11	34	procedure	procedure	NN
cord-011327-zsoc4wec	11	35	to	to	TO
cord-011327-zsoc4wec	11	36	be	be	VB
cord-011327-zsoc4wec	11	37	performed	perform	VBN
cord-011327-zsoc4wec	11	38	.	.	.
cord-011327-zsoc4wec	12	1	Such	such	JJ
cord-011327-zsoc4wec	12	2	time	time	NN
cord-011327-zsoc4wec	12	3	frames	frame	NNS
cord-011327-zsoc4wec	12	4	should	should	MD
cord-011327-zsoc4wec	12	5	ideally	ideally	RB
cord-011327-zsoc4wec	12	6	be	be	VB
cord-011327-zsoc4wec	12	7	determined	determine	VBN
cord-011327-zsoc4wec	12	8	in	in	IN
cord-011327-zsoc4wec	12	9	multicentre	multicentre	NNP
cord-011327-zsoc4wec	12	10	studies	study	NNS
cord-011327-zsoc4wec	12	11	randomising	randomise	VBG
cord-011327-zsoc4wec	12	12	critically	critically	RB
cord-011327-zsoc4wec	12	13	ill	ill	JJ
cord-011327-zsoc4wec	12	14	patients	patient	NNS
cord-011327-zsoc4wec	12	15	to	to	IN
cord-011327-zsoc4wec	12	16	different	different	JJ
cord-011327-zsoc4wec	12	17	timing	timing	NN
cord-011327-zsoc4wec	12	18	of	of	IN
cord-011327-zsoc4wec	12	19	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	12	20	administration	administration	NN
cord-011327-zsoc4wec	12	21	.	.	.
cord-011327-zsoc4wec	13	1	In	in	IN
cord-011327-zsoc4wec	13	2	the	the	DT
cord-011327-zsoc4wec	13	3	interim	interim	NN
cord-011327-zsoc4wec	13	4	,	,	,
cord-011327-zsoc4wec	13	5	extrapolation	extrapolation	NN
cord-011327-zsoc4wec	13	6	from	from	IN
cord-011327-zsoc4wec	13	7	populations	population	NNS
cord-011327-zsoc4wec	13	8	that	that	WDT
cord-011327-zsoc4wec	13	9	are	be	VBP
cord-011327-zsoc4wec	13	10	not	not	RB
cord-011327-zsoc4wec	13	11	critically	critically	RB
cord-011327-zsoc4wec	13	12	ill	ill	JJ
cord-011327-zsoc4wec	13	13	and	and	CC
cord-011327-zsoc4wec	13	14	from	from	IN
cord-011327-zsoc4wec	13	15	database	database	NN
cord-011327-zsoc4wec	13	16	analyses	analysis	NNS
cord-011327-zsoc4wec	13	17	suggests	suggest	VBZ
cord-011327-zsoc4wec	13	18	that	that	IN
cord-011327-zsoc4wec	13	19	prophylactic	prophylactic	JJ
cord-011327-zsoc4wec	13	20	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	13	21	therapy	therapy	NN
cord-011327-zsoc4wec	13	22	is	be	VBZ
cord-011327-zsoc4wec	13	23	generally	generally	RB
cord-011327-zsoc4wec	13	24	best	well	RBS
cord-011327-zsoc4wec	13	25	timed	time	VBN
cord-011327-zsoc4wec	13	26	to	to	IN
cord-011327-zsoc4wec	13	27	around	around	IN
cord-011327-zsoc4wec	13	28	1	1	CD
cord-011327-zsoc4wec	13	29	h	h	NN
cord-011327-zsoc4wec	13	30	before	before	IN
cord-011327-zsoc4wec	13	31	performance	performance	NN
cord-011327-zsoc4wec	13	32	of	of	IN
cord-011327-zsoc4wec	13	33	invasive	invasive	JJ
cord-011327-zsoc4wec	13	34	procedures	procedure	NNS
cord-011327-zsoc4wec	13	35	[	[	-LRB-
cord-011327-zsoc4wec	13	36	11	11	CD
cord-011327-zsoc4wec	13	37	,	,	,
cord-011327-zsoc4wec	13	38	12	12	CD
cord-011327-zsoc4wec	13	39	]	]	-RRB-
cord-011327-zsoc4wec	13	40	.	.	.
cord-011327-zsoc4wec	14	1	Prevalence	prevalence	NN
cord-011327-zsoc4wec	14	2	:	:	:
cord-011327-zsoc4wec	15	1	Several	several	JJ
cord-011327-zsoc4wec	15	2	studies	study	NNS
cord-011327-zsoc4wec	15	3	suggest	suggest	VBP
cord-011327-zsoc4wec	15	4	that	that	IN
cord-011327-zsoc4wec	15	5	prophylactic	prophylactic	JJ
cord-011327-zsoc4wec	15	6	administration	administration	NN
cord-011327-zsoc4wec	15	7	of	of	IN
cord-011327-zsoc4wec	15	8	antimicrobials	antimicrobial	NNS
cord-011327-zsoc4wec	15	9	is	be	VBZ
cord-011327-zsoc4wec	15	10	commonly	commonly	RB
cord-011327-zsoc4wec	15	11	practiced	practice	VBN
cord-011327-zsoc4wec	15	12	in	in	IN
cord-011327-zsoc4wec	15	13	the	the	DT
cord-011327-zsoc4wec	15	14	ICU	ICU	NNP
cord-011327-zsoc4wec	15	15	.	.	.
cord-011327-zsoc4wec	16	1	A	a	DT
cord-011327-zsoc4wec	16	2	single	single	JJ
cord-011327-zsoc4wec	16	3	-	-	HYPH
cord-011327-zsoc4wec	16	4	centre	centre	NN
cord-011327-zsoc4wec	16	5	prospective	prospective	JJ
cord-011327-zsoc4wec	16	6	study	study	NN
cord-011327-zsoc4wec	16	7	conducted	conduct	VBN
cord-011327-zsoc4wec	16	8	in	in	IN
cord-011327-zsoc4wec	16	9	Belgium	Belgium	NNP
cord-011327-zsoc4wec	16	10	showed	show	VBD
cord-011327-zsoc4wec	16	11	that	that	IN
cord-011327-zsoc4wec	16	12	among	among	IN
cord-011327-zsoc4wec	16	13	10,731	10,731	CD
cord-011327-zsoc4wec	16	14	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	16	15	treatment	treatment	NN
cord-011327-zsoc4wec	16	16	courses	course	NNS
cord-011327-zsoc4wec	16	17	recorded	record	VBN
cord-011327-zsoc4wec	16	18	for	for	IN
cord-011327-zsoc4wec	16	19	3	3	CD
cord-011327-zsoc4wec	16	20	years	year	NNS
cord-011327-zsoc4wec	16	21	,	,	,
cord-011327-zsoc4wec	16	22	42	42	CD
cord-011327-zsoc4wec	16	23	%	%	NN
cord-011327-zsoc4wec	16	24	(	(	-LRB-
cord-011327-zsoc4wec	16	25	n	n	NN
cord-011327-zsoc4wec	16	26	=	=	SYM
cord-011327-zsoc4wec	16	27	4525	4525	CD
cord-011327-zsoc4wec	16	28	)	)	-RRB-
cord-011327-zsoc4wec	16	29	were	be	VBD
cord-011327-zsoc4wec	16	30	prescribed	prescribe	VBN
cord-011327-zsoc4wec	16	31	for	for	IN
cord-011327-zsoc4wec	16	32	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	16	33	[	[	-LRB-
cord-011327-zsoc4wec	16	34	13	13	CD
cord-011327-zsoc4wec	16	35	]	]	-RRB-
cord-011327-zsoc4wec	16	36	.	.	.
cord-011327-zsoc4wec	17	1	A	a	DT
cord-011327-zsoc4wec	17	2	nationwide	nationwide	JJ
cord-011327-zsoc4wec	17	3	,	,	,
cord-011327-zsoc4wec	17	4	single	single	JJ
cord-011327-zsoc4wec	17	5	-	-	HYPH
cord-011327-zsoc4wec	17	6	day	day	NN
cord-011327-zsoc4wec	17	7	survey	survey	NN
cord-011327-zsoc4wec	17	8	conducted	conduct	VBN
cord-011327-zsoc4wec	17	9	among	among	IN
cord-011327-zsoc4wec	17	10	52	52	CD
cord-011327-zsoc4wec	17	11	ICUs	icu	NNS
cord-011327-zsoc4wec	17	12	in	in	IN
cord-011327-zsoc4wec	17	13	Japan	Japan	NNP
cord-011327-zsoc4wec	17	14	found	find	VBD
cord-011327-zsoc4wec	17	15	that	that	IN
cord-011327-zsoc4wec	17	16	34	34	CD
cord-011327-zsoc4wec	17	17	%	%	NN
cord-011327-zsoc4wec	17	18	(	(	-LRB-
cord-011327-zsoc4wec	17	19	n	n	NN
cord-011327-zsoc4wec	17	20	=	=	SYM
cord-011327-zsoc4wec	17	21	331/1028	331/1028	CD
cord-011327-zsoc4wec	17	22	)	)	-RRB-
cord-011327-zsoc4wec	17	23	of	of	IN
cord-011327-zsoc4wec	17	24	the	the	DT
cord-011327-zsoc4wec	17	25	prescriptions	prescription	NNS
cord-011327-zsoc4wec	17	26	for	for	IN
cord-011327-zsoc4wec	17	27	intravenous	intravenous	JJ
cord-011327-zsoc4wec	17	28	antibiotics	antibiotic	NNS
cord-011327-zsoc4wec	17	29	written	write	VBN
cord-011327-zsoc4wec	17	30	that	that	DT
cord-011327-zsoc4wec	17	31	day	day	NN
cord-011327-zsoc4wec	17	32	were	be	VBD
cord-011327-zsoc4wec	17	33	for	for	IN
cord-011327-zsoc4wec	17	34	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	17	35	[	[	-LRB-
cord-011327-zsoc4wec	17	36	14	14	CD
cord-011327-zsoc4wec	17	37	]	]	-RRB-
cord-011327-zsoc4wec	17	38	.	.	.
cord-011327-zsoc4wec	18	1	Antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	18	2	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	18	3	may	may	MD
cord-011327-zsoc4wec	18	4	be	be	VB
cord-011327-zsoc4wec	18	5	administered	administer	VBN
cord-011327-zsoc4wec	18	6	to	to	IN
cord-011327-zsoc4wec	18	7	patients	patient	NNS
cord-011327-zsoc4wec	18	8	undergoing	undergo	VBG
cord-011327-zsoc4wec	18	9	a	a	DT
cord-011327-zsoc4wec	18	10	surgical	surgical	JJ
cord-011327-zsoc4wec	18	11	procedure	procedure	NN
cord-011327-zsoc4wec	18	12	during	during	IN
cord-011327-zsoc4wec	18	13	their	-PRON-	PRP$
cord-011327-zsoc4wec	18	14	ICU	ICU	NNP
cord-011327-zsoc4wec	18	15	stay	stay	NN
cord-011327-zsoc4wec	18	16	and	and	CC
cord-011327-zsoc4wec	18	17	as	as	IN
cord-011327-zsoc4wec	18	18	a	a	DT
cord-011327-zsoc4wec	18	19	non	non	JJ
cord-011327-zsoc4wec	18	20	-	-	JJ
cord-011327-zsoc4wec	18	21	surgical	surgical	JJ
cord-011327-zsoc4wec	18	22	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	18	23	to	to	IN
cord-011327-zsoc4wec	18	24	ICU	ICU	NNP
cord-011327-zsoc4wec	18	25	patients	patient	NNS
cord-011327-zsoc4wec	18	26	who	who	WP
cord-011327-zsoc4wec	18	27	undergo	undergo	VBP
cord-011327-zsoc4wec	18	28	insertion	insertion	NN
cord-011327-zsoc4wec	18	29	of	of	IN
cord-011327-zsoc4wec	18	30	an	an	DT
cord-011327-zsoc4wec	18	31	external	external	JJ
cord-011327-zsoc4wec	18	32	-	-	HYPH
cord-011327-zsoc4wec	18	33	internal	internal	JJ
cord-011327-zsoc4wec	18	34	foreign	foreign	JJ
cord-011327-zsoc4wec	18	35	body	body	NN
cord-011327-zsoc4wec	18	36	that	that	WDT
cord-011327-zsoc4wec	18	37	remains	remain	VBZ
cord-011327-zsoc4wec	18	38	in	in	IN
cord-011327-zsoc4wec	18	39	situ	situ	NN
cord-011327-zsoc4wec	18	40	for	for	IN
cord-011327-zsoc4wec	18	41	a	a	DT
cord-011327-zsoc4wec	18	42	prolonged	prolonged	JJ
cord-011327-zsoc4wec	18	43	period	period	NN
cord-011327-zsoc4wec	18	44	of	of	IN
cord-011327-zsoc4wec	18	45	time	time	NN
cord-011327-zsoc4wec	18	46	.	.	.
cord-011327-zsoc4wec	19	1	These	these	DT
cord-011327-zsoc4wec	19	2	two	two	CD
cord-011327-zsoc4wec	19	3	clinical	clinical	JJ
cord-011327-zsoc4wec	19	4	scenarios	scenario	NNS
cord-011327-zsoc4wec	19	5	differ	differ	VBP
cord-011327-zsoc4wec	19	6	and	and	CC
cord-011327-zsoc4wec	19	7	are	be	VBP
cord-011327-zsoc4wec	19	8	,	,	,
cord-011327-zsoc4wec	19	9	therefore	therefore	RB
cord-011327-zsoc4wec	19	10	,	,	,
cord-011327-zsoc4wec	19	11	discussed	discuss	VBN
cord-011327-zsoc4wec	19	12	separately	separately	RB
cord-011327-zsoc4wec	19	13	.	.	.
cord-011327-zsoc4wec	20	1	Surgical	surgical	JJ
cord-011327-zsoc4wec	20	2	procedures	procedure	NNS
cord-011327-zsoc4wec	20	3	:	:	:
cord-011327-zsoc4wec	20	4	Surgical	surgical	JJ
cord-011327-zsoc4wec	20	5	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	20	6	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	20	7	(	(	-LRB-
cord-011327-zsoc4wec	20	8	SAP	SAP	NNP
cord-011327-zsoc4wec	20	9	)	)	-RRB-
cord-011327-zsoc4wec	20	10	for	for	IN
cord-011327-zsoc4wec	20	11	prevention	prevention	NN
cord-011327-zsoc4wec	20	12	of	of	IN
cord-011327-zsoc4wec	20	13	surgical	surgical	JJ
cord-011327-zsoc4wec	20	14	site	site	NN
cord-011327-zsoc4wec	20	15	infections	infection	NNS
cord-011327-zsoc4wec	20	16	is	be	VBZ
cord-011327-zsoc4wec	20	17	the	the	DT
cord-011327-zsoc4wec	20	18	most	most	RBS
cord-011327-zsoc4wec	20	19	frequent	frequent	JJ
cord-011327-zsoc4wec	20	20	hospital	hospital	NN
cord-011327-zsoc4wec	20	21	-	-	HYPH
cord-011327-zsoc4wec	20	22	wide	wide	JJ
cord-011327-zsoc4wec	20	23	indication	indication	NN
cord-011327-zsoc4wec	20	24	for	for	IN
cord-011327-zsoc4wec	20	25	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	20	26	use	use	NN
cord-011327-zsoc4wec	20	27	.	.	.
cord-011327-zsoc4wec	21	1	However	however	RB
cord-011327-zsoc4wec	21	2	,	,	,
cord-011327-zsoc4wec	21	3	SAP	SAP	NNP
cord-011327-zsoc4wec	21	4	is	be	VBZ
cord-011327-zsoc4wec	21	5	also	also	RB
cord-011327-zsoc4wec	21	6	commonly	commonly	RB
cord-011327-zsoc4wec	21	7	practiced	practice	VBN
cord-011327-zsoc4wec	21	8	in	in	IN
cord-011327-zsoc4wec	21	9	many	many	JJ
cord-011327-zsoc4wec	21	10	ICUs	icu	NNS
cord-011327-zsoc4wec	21	11	.	.	.
cord-011327-zsoc4wec	22	1	A	a	DT
cord-011327-zsoc4wec	22	2	single	single	JJ
cord-011327-zsoc4wec	22	3	-	-	HYPH
cord-011327-zsoc4wec	22	4	centre	centre	NN
cord-011327-zsoc4wec	22	5	study	study	NN
cord-011327-zsoc4wec	22	6	conducted	conduct	VBN
cord-011327-zsoc4wec	22	7	recently	recently	RB
cord-011327-zsoc4wec	22	8	in	in	IN
cord-011327-zsoc4wec	22	9	a	a	DT
cord-011327-zsoc4wec	22	10	Belgian	belgian	JJ
cord-011327-zsoc4wec	22	11	ICU	ICU	NNP
cord-011327-zsoc4wec	22	12	showed	show	VBD
cord-011327-zsoc4wec	22	13	that	that	IN
cord-011327-zsoc4wec	22	14	SAP	SAP	NNP
cord-011327-zsoc4wec	22	15	and	and	CC
cord-011327-zsoc4wec	22	16	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	22	17	for	for	IN
cord-011327-zsoc4wec	22	18	immunocompromised	immunocompromised	JJ
cord-011327-zsoc4wec	22	19	patients	patient	NNS
cord-011327-zsoc4wec	22	20	constituted	constitute	VBD
cord-011327-zsoc4wec	22	21	two	two	CD
cord-011327-zsoc4wec	22	22	-	-	HYPH
cord-011327-zsoc4wec	22	23	thirds	third	NNS
cord-011327-zsoc4wec	22	24	of	of	IN
cord-011327-zsoc4wec	22	25	prophylactic	prophylactic	JJ
cord-011327-zsoc4wec	22	26	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	22	27	treatments	treatment	NNS
cord-011327-zsoc4wec	22	28	prescribed	prescribe	VBN
cord-011327-zsoc4wec	22	29	[	[	-LRB-
cord-011327-zsoc4wec	22	30	13	13	CD
cord-011327-zsoc4wec	22	31	]	]	-RRB-
cord-011327-zsoc4wec	22	32	.	.	.
cord-011327-zsoc4wec	23	1	In	in	IN
cord-011327-zsoc4wec	23	2	non	non	JJ
cord-011327-zsoc4wec	23	3	-	-	JJ
cord-011327-zsoc4wec	23	4	ICU	icu	JJ
cord-011327-zsoc4wec	23	5	patients	patient	NNS
cord-011327-zsoc4wec	23	6	,	,	,
cord-011327-zsoc4wec	23	7	it	-PRON-	PRP
cord-011327-zsoc4wec	23	8	is	be	VBZ
cord-011327-zsoc4wec	23	9	recommended	recommend	VBN
cord-011327-zsoc4wec	23	10	that	that	IN
cord-011327-zsoc4wec	23	11	SAP	SAP	NNP
cord-011327-zsoc4wec	23	12	be	be	VB
cord-011327-zsoc4wec	23	13	administered	administer	VBN
cord-011327-zsoc4wec	23	14	30	30	CD
cord-011327-zsoc4wec	23	15	-	-	SYM
cord-011327-zsoc4wec	23	16	60	60	CD
cord-011327-zsoc4wec	23	17	min	min	NN
cord-011327-zsoc4wec	23	18	before	before	IN
cord-011327-zsoc4wec	23	19	surgical	surgical	JJ
cord-011327-zsoc4wec	23	20	incision	incision	NN
cord-011327-zsoc4wec	23	21	to	to	TO
cord-011327-zsoc4wec	23	22	enable	enable	VB
cord-011327-zsoc4wec	23	23	achievement	achievement	NN
cord-011327-zsoc4wec	23	24	of	of	IN
cord-011327-zsoc4wec	23	25	a	a	DT
cord-011327-zsoc4wec	23	26	high	high	JJ
cord-011327-zsoc4wec	23	27	serum	serum	NN
cord-011327-zsoc4wec	23	28	concentration	concentration	NN
cord-011327-zsoc4wec	23	29	of	of	IN
cord-011327-zsoc4wec	23	30	antibiotics	antibiotic	NNS
cord-011327-zsoc4wec	23	31	prior	prior	RB
cord-011327-zsoc4wec	23	32	to	to	IN
cord-011327-zsoc4wec	23	33	incision	incision	NN
cord-011327-zsoc4wec	23	34	[	[	-LRB-
cord-011327-zsoc4wec	23	35	11	11	CD
cord-011327-zsoc4wec	23	36	,	,	,
cord-011327-zsoc4wec	23	37	12	12	CD
cord-011327-zsoc4wec	23	38	]	]	-RRB-
cord-011327-zsoc4wec	23	39	.	.	.
cord-011327-zsoc4wec	24	1	Re	re	NN
cord-011327-zsoc4wec	24	2	-	-	NN
cord-011327-zsoc4wec	24	3	injection	injection	NN
cord-011327-zsoc4wec	24	4	is	be	VBZ
cord-011327-zsoc4wec	24	5	recommended	recommend	VBN
cord-011327-zsoc4wec	24	6	during	during	IN
cord-011327-zsoc4wec	24	7	the	the	DT
cord-011327-zsoc4wec	24	8	procedure	procedure	NN
cord-011327-zsoc4wec	24	9	every	every	DT
cord-011327-zsoc4wec	24	10	two	two	CD
cord-011327-zsoc4wec	24	11	half	half	RB
cord-011327-zsoc4wec	24	12	-	-	HYPH
cord-011327-zsoc4wec	24	13	lives	life	NNS
cord-011327-zsoc4wec	24	14	of	of	IN
cord-011327-zsoc4wec	24	15	the	the	DT
cord-011327-zsoc4wec	24	16	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	24	17	[	[	-LRB-
cord-011327-zsoc4wec	24	18	12	12	CD
cord-011327-zsoc4wec	24	19	]	]	-RRB-
cord-011327-zsoc4wec	24	20	.	.	.
cord-011327-zsoc4wec	25	1	If	if	IN
cord-011327-zsoc4wec	25	2	surgery	surgery	NN
cord-011327-zsoc4wec	25	3	is	be	VBZ
cord-011327-zsoc4wec	25	4	conducted	conduct	VBN
cord-011327-zsoc4wec	25	5	prior	prior	RB
cord-011327-zsoc4wec	25	6	to	to	IN
cord-011327-zsoc4wec	25	7	ICU	ICU	NNP
cord-011327-zsoc4wec	25	8	admission	admission	NN
cord-011327-zsoc4wec	25	9	and/or	and/or	CC
cord-011327-zsoc4wec	25	10	within	within	IN
cord-011327-zsoc4wec	25	11	the	the	DT
cord-011327-zsoc4wec	25	12	first	first	JJ
cord-011327-zsoc4wec	25	13	48	48	CD
cord-011327-zsoc4wec	25	14	h	h	NN
cord-011327-zsoc4wec	25	15	of	of	IN
cord-011327-zsoc4wec	25	16	ICU	ICU	NNP
cord-011327-zsoc4wec	25	17	admission	admission	NN
cord-011327-zsoc4wec	25	18	,	,	,
cord-011327-zsoc4wec	25	19	the	the	DT
cord-011327-zsoc4wec	25	20	recommendations	recommendation	NNS
cord-011327-zsoc4wec	25	21	for	for	IN
cord-011327-zsoc4wec	25	22	SAP	SAP	NNP
cord-011327-zsoc4wec	25	23	remain	remain	VBP
cord-011327-zsoc4wec	25	24	unchanged	unchanged	JJ
cord-011327-zsoc4wec	25	25	;	;	:
cord-011327-zsoc4wec	25	26	they	-PRON-	PRP
cord-011327-zsoc4wec	25	27	are	be	VBP
cord-011327-zsoc4wec	25	28	similar	similar	JJ
cord-011327-zsoc4wec	25	29	to	to	IN
cord-011327-zsoc4wec	25	30	the	the	DT
cord-011327-zsoc4wec	25	31	recommendations	recommendation	NNS
cord-011327-zsoc4wec	25	32	of	of	IN
cord-011327-zsoc4wec	25	33	any	any	DT
cord-011327-zsoc4wec	25	34	department	department	NN
cord-011327-zsoc4wec	25	35	of	of	IN
cord-011327-zsoc4wec	25	36	emergency	emergency	NN
cord-011327-zsoc4wec	25	37	medicine	medicine	NN
cord-011327-zsoc4wec	25	38	or	or	CC
cord-011327-zsoc4wec	25	39	ward	ward	NN
cord-011327-zsoc4wec	25	40	[	[	-LRB-
cord-011327-zsoc4wec	25	41	15	15	CD
cord-011327-zsoc4wec	25	42	]	]	-RRB-
cord-011327-zsoc4wec	25	43	.	.	.
cord-011327-zsoc4wec	26	1	However	however	RB
cord-011327-zsoc4wec	26	2	,	,	,
cord-011327-zsoc4wec	26	3	in	in	IN
cord-011327-zsoc4wec	26	4	ICU	ICU	NNP
cord-011327-zsoc4wec	26	5	,	,	,
cord-011327-zsoc4wec	26	6	patients	patient	NNS
cord-011327-zsoc4wec	26	7	undergoing	undergo	VBG
cord-011327-zsoc4wec	26	8	unplanned	unplanned	JJ
cord-011327-zsoc4wec	26	9	surgery	surgery	NN
cord-011327-zsoc4wec	26	10	after	after	IN
cord-011327-zsoc4wec	26	11	staying	stay	VBG
cord-011327-zsoc4wec	26	12	>	>	XX
cord-011327-zsoc4wec	26	13	2	2	CD
cord-011327-zsoc4wec	26	14	days	day	NNS
cord-011327-zsoc4wec	26	15	in	in	IN
cord-011327-zsoc4wec	26	16	the	the	DT
cord-011327-zsoc4wec	26	17	ICU	ICU	NNP
cord-011327-zsoc4wec	26	18	other	other	JJ
cord-011327-zsoc4wec	26	19	considerations	consideration	NNS
cord-011327-zsoc4wec	26	20	come	come	VBP
cord-011327-zsoc4wec	26	21	into	into	IN
cord-011327-zsoc4wec	26	22	play	play	NN
cord-011327-zsoc4wec	26	23	.	.	.
cord-011327-zsoc4wec	27	1	Colonization	colonization	NN
cord-011327-zsoc4wec	27	2	with	with	IN
cord-011327-zsoc4wec	27	3	MDR	MDR	NNP
cord-011327-zsoc4wec	27	4	pathogens	pathogen	NNS
cord-011327-zsoc4wec	27	5	increases	increase	NNS
cord-011327-zsoc4wec	27	6	during	during	IN
cord-011327-zsoc4wec	27	7	the	the	DT
cord-011327-zsoc4wec	27	8	hospital	hospital	NN
cord-011327-zsoc4wec	27	9	stay	stay	NN
cord-011327-zsoc4wec	27	10	[	[	-LRB-
cord-011327-zsoc4wec	27	11	16	16	CD
cord-011327-zsoc4wec	27	12	]	]	-RRB-
cord-011327-zsoc4wec	27	13	.	.	.
cord-011327-zsoc4wec	28	1	Prior	prior	JJ
cord-011327-zsoc4wec	28	2	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	28	3	treatment	treatment	NN
cord-011327-zsoc4wec	28	4	and	and	CC
cord-011327-zsoc4wec	28	5	prior	prior	JJ
cord-011327-zsoc4wec	28	6	environmental	environmental	JJ
cord-011327-zsoc4wec	28	7	exposure	exposure	NN
cord-011327-zsoc4wec	28	8	also	also	RB
cord-011327-zsoc4wec	28	9	affect	affect	VBP
cord-011327-zsoc4wec	28	10	the	the	DT
cord-011327-zsoc4wec	28	11	prevalence	prevalence	NN
cord-011327-zsoc4wec	28	12	of	of	IN
cord-011327-zsoc4wec	28	13	colonization	colonization	NN
cord-011327-zsoc4wec	28	14	by	by	IN
cord-011327-zsoc4wec	28	15	MDR	MDR	NNP
cord-011327-zsoc4wec	28	16	pathogens	pathogen	NNS
cord-011327-zsoc4wec	28	17	[	[	-LRB-
cord-011327-zsoc4wec	28	18	17	17	CD
cord-011327-zsoc4wec	28	19	]	]	-RRB-
cord-011327-zsoc4wec	28	20	.	.	.
cord-011327-zsoc4wec	29	1	In	in	IN
cord-011327-zsoc4wec	29	2	such	such	JJ
cord-011327-zsoc4wec	29	3	cases	case	NNS
cord-011327-zsoc4wec	29	4	,	,	,
cord-011327-zsoc4wec	29	5	the	the	DT
cord-011327-zsoc4wec	29	6	spectrum	spectrum	NN
cord-011327-zsoc4wec	29	7	of	of	IN
cord-011327-zsoc4wec	29	8	antibiotics	antibiotic	NNS
cord-011327-zsoc4wec	29	9	required	require	VBN
cord-011327-zsoc4wec	29	10	constitutes	constitute	VBZ
cord-011327-zsoc4wec	29	11	a	a	DT
cord-011327-zsoc4wec	29	12	major	major	JJ
cord-011327-zsoc4wec	29	13	challenge	challenge	NN
cord-011327-zsoc4wec	29	14	because	because	IN
cord-011327-zsoc4wec	29	15	of	of	IN
cord-011327-zsoc4wec	29	16	the	the	DT
cord-011327-zsoc4wec	29	17	potential	potential	JJ
cord-011327-zsoc4wec	29	18	need	need	NN
cord-011327-zsoc4wec	29	19	to	to	TO
cord-011327-zsoc4wec	29	20	cover	cover	VB
cord-011327-zsoc4wec	29	21	and	and	CC
cord-011327-zsoc4wec	29	22	manage	manage	VB
cord-011327-zsoc4wec	29	23	MDRs	mdr	NNS
cord-011327-zsoc4wec	29	24	in	in	IN
cord-011327-zsoc4wec	29	25	the	the	DT
cord-011327-zsoc4wec	29	26	operative	operative	NN
cord-011327-zsoc4wec	29	27	setting	setting	NN
cord-011327-zsoc4wec	29	28	and	and	CC
cord-011327-zsoc4wec	29	29	because	because	IN
cord-011327-zsoc4wec	29	30	in	in	IN
cord-011327-zsoc4wec	29	31	fragile	fragile	JJ
cord-011327-zsoc4wec	29	32	patients	patient	NNS
cord-011327-zsoc4wec	29	33	,	,	,
cord-011327-zsoc4wec	29	34	there	there	EX
cord-011327-zsoc4wec	29	35	is	be	VBZ
cord-011327-zsoc4wec	29	36	an	an	DT
cord-011327-zsoc4wec	29	37	unproven	unproven	JJ
cord-011327-zsoc4wec	29	38	concern	concern	NN
cord-011327-zsoc4wec	29	39	not	not	RB
cord-011327-zsoc4wec	29	40	only	only	RB
cord-011327-zsoc4wec	29	41	for	for	IN
cord-011327-zsoc4wec	29	42	surgical	surgical	JJ
cord-011327-zsoc4wec	29	43	site	site	NN
cord-011327-zsoc4wec	29	44	,	,	,
cord-011327-zsoc4wec	29	45	but	but	CC
cord-011327-zsoc4wec	29	46	also	also	RB
cord-011327-zsoc4wec	29	47	for	for	IN
cord-011327-zsoc4wec	29	48	systemic	systemic	JJ
cord-011327-zsoc4wec	29	49	infection	infection	NN
cord-011327-zsoc4wec	29	50	[	[	-LRB-
cord-011327-zsoc4wec	29	51	18	18	CD
cord-011327-zsoc4wec	29	52	]	]	-RRB-
cord-011327-zsoc4wec	29	53	.	.	.
cord-011327-zsoc4wec	30	1	A	a	DT
cord-011327-zsoc4wec	30	2	single	single	JJ
cord-011327-zsoc4wec	30	3	-	-	HYPH
cord-011327-zsoc4wec	30	4	centre	centre	NN
cord-011327-zsoc4wec	30	5	,	,	,
cord-011327-zsoc4wec	30	6	observational	observational	JJ
cord-011327-zsoc4wec	30	7	study	study	NN
cord-011327-zsoc4wec	30	8	which	which	WDT
cord-011327-zsoc4wec	30	9	reported	report	VBD
cord-011327-zsoc4wec	30	10	on	on	IN
cord-011327-zsoc4wec	30	11	a	a	DT
cord-011327-zsoc4wec	30	12	small	small	JJ
cord-011327-zsoc4wec	30	13	number	number	NN
cord-011327-zsoc4wec	30	14	of	of	IN
cord-011327-zsoc4wec	30	15	patients	patient	NNS
cord-011327-zsoc4wec	30	16	(	(	-LRB-
cord-011327-zsoc4wec	30	17	n	n	NN
cord-011327-zsoc4wec	30	18	=	=	SYM
cord-011327-zsoc4wec	30	19	44	44	CD
cord-011327-zsoc4wec	30	20	)	)	-RRB-
cord-011327-zsoc4wec	30	21	has	have	VBZ
cord-011327-zsoc4wec	30	22	shown	show	VBN
cord-011327-zsoc4wec	30	23	great	great	JJ
cord-011327-zsoc4wec	30	24	variability	variability	NN
cord-011327-zsoc4wec	30	25	of	of	IN
cord-011327-zsoc4wec	30	26	practices	practice	NNS
cord-011327-zsoc4wec	30	27	in	in	IN
cord-011327-zsoc4wec	30	28	these	these	DT
cord-011327-zsoc4wec	30	29	patients	patient	NNS
cord-011327-zsoc4wec	30	30	[	[	-LRB-
cord-011327-zsoc4wec	30	31	19	19	CD
cord-011327-zsoc4wec	30	32	]	]	-RRB-
cord-011327-zsoc4wec	30	33	.	.	.
cord-011327-zsoc4wec	31	1	To	to	IN
cord-011327-zsoc4wec	31	2	date	date	NN
cord-011327-zsoc4wec	31	3	,	,	,
cord-011327-zsoc4wec	31	4	there	there	EX
cord-011327-zsoc4wec	31	5	is	be	VBZ
cord-011327-zsoc4wec	31	6	no	no	DT
cord-011327-zsoc4wec	31	7	evidence	evidence	NN
cord-011327-zsoc4wec	31	8	to	to	TO
cord-011327-zsoc4wec	31	9	support	support	VB
cord-011327-zsoc4wec	31	10	the	the	DT
cord-011327-zsoc4wec	31	11	universal	universal	JJ
cord-011327-zsoc4wec	31	12	use	use	NN
cord-011327-zsoc4wec	31	13	of	of	IN
cord-011327-zsoc4wec	31	14	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	31	15	targeted	target	VBN
cord-011327-zsoc4wec	31	16	against	against	IN
cord-011327-zsoc4wec	31	17	MDR	MDR	NNP
cord-011327-zsoc4wec	31	18	.	.	.
cord-011327-zsoc4wec	32	1	This	this	DT
cord-011327-zsoc4wec	32	2	approach	approach	NN
cord-011327-zsoc4wec	32	3	should	should	MD
cord-011327-zsoc4wec	32	4	be	be	VB
cord-011327-zsoc4wec	32	5	investigated	investigate	VBN
cord-011327-zsoc4wec	32	6	in	in	IN
cord-011327-zsoc4wec	32	7	future	future	JJ
cord-011327-zsoc4wec	32	8	studies	study	NNS
cord-011327-zsoc4wec	32	9	,	,	,
cord-011327-zsoc4wec	32	10	as	as	IN
cord-011327-zsoc4wec	32	11	it	-PRON-	PRP
cord-011327-zsoc4wec	32	12	can	can	MD
cord-011327-zsoc4wec	32	13	constitute	constitute	VB
cord-011327-zsoc4wec	32	14	a	a	DT
cord-011327-zsoc4wec	32	15	vicious	vicious	JJ
cord-011327-zsoc4wec	32	16	circle	circle	NN
cord-011327-zsoc4wec	32	17	for	for	IN
cord-011327-zsoc4wec	32	18	the	the	DT
cord-011327-zsoc4wec	32	19	development	development	NN
cord-011327-zsoc4wec	32	20	of	of	IN
cord-011327-zsoc4wec	32	21	MDR	MDR	NNP
cord-011327-zsoc4wec	32	22	.	.	.
cord-011327-zsoc4wec	33	1	Some	some	DT
cord-011327-zsoc4wec	33	2	of	of	IN
cord-011327-zsoc4wec	33	3	the	the	DT
cord-011327-zsoc4wec	33	4	multiple	multiple	JJ
cord-011327-zsoc4wec	33	5	factors	factor	NNS
cord-011327-zsoc4wec	33	6	that	that	WDT
cord-011327-zsoc4wec	33	7	should	should	MD
cord-011327-zsoc4wec	33	8	be	be	VB
cord-011327-zsoc4wec	33	9	taken	take	VBN
cord-011327-zsoc4wec	33	10	into	into	IN
cord-011327-zsoc4wec	33	11	account	account	NN
cord-011327-zsoc4wec	33	12	when	when	WRB
cord-011327-zsoc4wec	33	13	determining	determine	VBG
cord-011327-zsoc4wec	33	14	the	the	DT
cord-011327-zsoc4wec	33	15	choice	choice	NN
cord-011327-zsoc4wec	33	16	of	of	IN
cord-011327-zsoc4wec	33	17	antibiotic	antibiotic	NN
cord-011327-zsoc4wec	33	18	in	in	IN
cord-011327-zsoc4wec	33	19	such	such	JJ
cord-011327-zsoc4wec	33	20	cases	case	NNS
cord-011327-zsoc4wec	33	21	are	be	VBP
cord-011327-zsoc4wec	33	22	presented	present	VBN
cord-011327-zsoc4wec	33	23	in	in	IN
cord-011327-zsoc4wec	33	24	Table	Table	NNP
cord-011327-zsoc4wec	33	25	1	1	CD
cord-011327-zsoc4wec	33	26	.	.	.
cord-011327-zsoc4wec	34	1	There	there	EX
cord-011327-zsoc4wec	34	2	are	be	VBP
cord-011327-zsoc4wec	34	3	no	no	DT
cord-011327-zsoc4wec	34	4	randomised	randomised	JJ
cord-011327-zsoc4wec	34	5	controlled	control	VBN
cord-011327-zsoc4wec	34	6	trials	trial	NNS
cord-011327-zsoc4wec	34	7	on	on	IN
cord-011327-zsoc4wec	34	8	the	the	DT
cord-011327-zsoc4wec	34	9	effects	effect	NNS
cord-011327-zsoc4wec	34	10	of	of	IN
cord-011327-zsoc4wec	34	11	timing	timing	NN
cord-011327-zsoc4wec	34	12	or	or	CC
cord-011327-zsoc4wec	34	13	choice	choice	NN
cord-011327-zsoc4wec	34	14	of	of	IN
cord-011327-zsoc4wec	34	15	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	34	16	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	34	17	on	on	IN
cord-011327-zsoc4wec	34	18	the	the	DT
cord-011327-zsoc4wec	34	19	outcomes	outcome	NNS
cord-011327-zsoc4wec	34	20	of	of	IN
cord-011327-zsoc4wec	34	21	ICU	ICU	NNP
cord-011327-zsoc4wec	34	22	patients	patient	NNS
cord-011327-zsoc4wec	34	23	requiring	require	VBG
cord-011327-zsoc4wec	34	24	unplanned	unplanned	JJ
cord-011327-zsoc4wec	34	25	surgical	surgical	JJ
cord-011327-zsoc4wec	34	26	procedures	procedure	NNS
cord-011327-zsoc4wec	34	27	.	.	.
cord-011327-zsoc4wec	35	1	Nor	nor	CC
cord-011327-zsoc4wec	35	2	are	be	VBP
cord-011327-zsoc4wec	35	3	there	there	EX
cord-011327-zsoc4wec	35	4	recommendations	recommendation	NNS
cord-011327-zsoc4wec	35	5	for	for	IN
cord-011327-zsoc4wec	35	6	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	35	7	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	35	8	in	in	IN
cord-011327-zsoc4wec	35	9	critically	critically	RB
cord-011327-zsoc4wec	35	10	ill	ill	JJ
cord-011327-zsoc4wec	35	11	patients	patient	NNS
cord-011327-zsoc4wec	35	12	.	.	.
cord-011327-zsoc4wec	36	1	Non	non	JJ
cord-011327-zsoc4wec	36	2	-	-	JJ
cord-011327-zsoc4wec	36	3	surgical	surgical	JJ
cord-011327-zsoc4wec	36	4	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	36	5	:	:	:
cord-011327-zsoc4wec	36	6	Many	many	JJ
cord-011327-zsoc4wec	36	7	ICU	ICU	NNP
cord-011327-zsoc4wec	36	8	patients	patient	NNS
cord-011327-zsoc4wec	36	9	require	require	VBP
cord-011327-zsoc4wec	36	10	insertion	insertion	NN
cord-011327-zsoc4wec	36	11	of	of	IN
cord-011327-zsoc4wec	36	12	an	an	DT
cord-011327-zsoc4wec	36	13	external	external	JJ
cord-011327-zsoc4wec	36	14	-	-	HYPH
cord-011327-zsoc4wec	36	15	internal	internal	JJ
cord-011327-zsoc4wec	36	16	foreign	foreign	JJ
cord-011327-zsoc4wec	36	17	body	body	NN
cord-011327-zsoc4wec	36	18	.	.	.
cord-011327-zsoc4wec	37	1	Questions	question	NNS
cord-011327-zsoc4wec	37	2	arise	arise	VBP
cord-011327-zsoc4wec	37	3	regarding	regard	VBG
cord-011327-zsoc4wec	37	4	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	37	5	before	before	IN
cord-011327-zsoc4wec	37	6	insertion	insertion	NN
cord-011327-zsoc4wec	37	7	and	and	CC
cord-011327-zsoc4wec	37	8	for	for	IN
cord-011327-zsoc4wec	37	9	tubing	tubing	NN
cord-011327-zsoc4wec	37	10	remaining	remain	VBG
cord-011327-zsoc4wec	37	11	in	in	IN
cord-011327-zsoc4wec	37	12	situ	situ	NN
cord-011327-zsoc4wec	37	13	for	for	IN
cord-011327-zsoc4wec	37	14	a	a	DT
cord-011327-zsoc4wec	37	15	prolonged	prolonged	JJ
cord-011327-zsoc4wec	37	16	period	period	NN
cord-011327-zsoc4wec	37	17	of	of	IN
cord-011327-zsoc4wec	37	18	time	time	NN
cord-011327-zsoc4wec	37	19	.	.	.
cord-011327-zsoc4wec	38	1	We	-PRON-	PRP
cord-011327-zsoc4wec	38	2	discuss	discuss	VBP
cord-011327-zsoc4wec	38	3	three	three	CD
cord-011327-zsoc4wec	38	4	of	of	IN
cord-011327-zsoc4wec	38	5	these	these	DT
cord-011327-zsoc4wec	38	6	many	many	JJ
cord-011327-zsoc4wec	38	7	dilemmas	dilemma	NNS
cord-011327-zsoc4wec	38	8	;	;	,
cord-011327-zsoc4wec	38	9	endotracheal	endotracheal	JJ
cord-011327-zsoc4wec	38	10	intubation	intubation	NN
cord-011327-zsoc4wec	38	11	due	due	IN
cord-011327-zsoc4wec	38	12	to	to	IN
cord-011327-zsoc4wec	38	13	an	an	DT
cord-011327-zsoc4wec	38	14	altered	altered	JJ
cord-011327-zsoc4wec	38	15	level	level	NN
cord-011327-zsoc4wec	38	16	of	of	IN
cord-011327-zsoc4wec	38	17	consciousness	consciousness	NN
cord-011327-zsoc4wec	38	18	,	,	,
cord-011327-zsoc4wec	38	19	chest	chest	NN
cord-011327-zsoc4wec	38	20	drain	drain	NN
cord-011327-zsoc4wec	38	21	insertion	insertion	NN
cord-011327-zsoc4wec	38	22	and	and	CC
cord-011327-zsoc4wec	38	23	insertion	insertion	NN
cord-011327-zsoc4wec	38	24	/	/	SYM
cord-011327-zsoc4wec	38	25	maintenance	maintenance	NN
cord-011327-zsoc4wec	38	26	of	of	IN
cord-011327-zsoc4wec	38	27	an	an	DT
cord-011327-zsoc4wec	38	28	intracranial	intracranial	JJ
cord-011327-zsoc4wec	38	29	ventricular	ventricular	JJ
cord-011327-zsoc4wec	38	30	drain	drain	NN
cord-011327-zsoc4wec	38	31	.	.	.
cord-011327-zsoc4wec	39	1	Endotracheal	endotracheal	JJ
cord-011327-zsoc4wec	39	2	intubation	intubation	NN
cord-011327-zsoc4wec	39	3	:	:	:
cord-011327-zsoc4wec	40	1	Prophylactic	prophylactic	JJ
cord-011327-zsoc4wec	40	2	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	40	3	treatment	treatment	NN
cord-011327-zsoc4wec	40	4	following	follow	VBG
cord-011327-zsoc4wec	40	5	endotracheal	endotracheal	NN
cord-011327-zsoc4wec	40	6	intubation	intubation	NN
cord-011327-zsoc4wec	40	7	of	of	IN
cord-011327-zsoc4wec	40	8	patients	patient	NNS
cord-011327-zsoc4wec	40	9	with	with	IN
cord-011327-zsoc4wec	40	10	an	an	DT
cord-011327-zsoc4wec	40	11	altered	altered	JJ
cord-011327-zsoc4wec	40	12	level	level	NN
cord-011327-zsoc4wec	40	13	of	of	IN
cord-011327-zsoc4wec	40	14	consciousness	consciousness	NN
cord-011327-zsoc4wec	40	15	is	be	VBZ
cord-011327-zsoc4wec	40	16	not	not	RB
cord-011327-zsoc4wec	40	17	recommended	recommend	VBN
cord-011327-zsoc4wec	40	18	in	in	IN
cord-011327-zsoc4wec	40	19	most	most	JJS
cord-011327-zsoc4wec	40	20	guidelines	guideline	NNS
cord-011327-zsoc4wec	40	21	for	for	IN
cord-011327-zsoc4wec	40	22	prevention	prevention	NN
cord-011327-zsoc4wec	40	23	of	of	IN
cord-011327-zsoc4wec	40	24	healthcare	healthcare	NN
cord-011327-zsoc4wec	40	25	-	-	HYPH
cord-011327-zsoc4wec	40	26	associated	associate	VBN
cord-011327-zsoc4wec	40	27	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	40	28	[	[	-LRB-
cord-011327-zsoc4wec	40	29	20	20	CD
cord-011327-zsoc4wec	40	30	,	,	,
cord-011327-zsoc4wec	40	31	21	21	CD
cord-011327-zsoc4wec	40	32	]	]	-RRB-
cord-011327-zsoc4wec	40	33	.	.	.
cord-011327-zsoc4wec	41	1	However	however	RB
cord-011327-zsoc4wec	41	2	,	,	,
cord-011327-zsoc4wec	41	3	French	french	JJ
cord-011327-zsoc4wec	41	4	guidelines	guideline	NNS
cord-011327-zsoc4wec	41	5	for	for	IN
cord-011327-zsoc4wec	41	6	the	the	DT
cord-011327-zsoc4wec	41	7	prevention	prevention	NN
cord-011327-zsoc4wec	41	8	,	,	,
cord-011327-zsoc4wec	41	9	diagnosis	diagnosis	NN
cord-011327-zsoc4wec	41	10	and	and	CC
cord-011327-zsoc4wec	41	11	treatment	treatment	NN
cord-011327-zsoc4wec	41	12	of	of	IN
cord-011327-zsoc4wec	41	13	hospital	hospital	NN
cord-011327-zsoc4wec	41	14	-	-	HYPH
cord-011327-zsoc4wec	41	15	acquired	acquire	VBN
cord-011327-zsoc4wec	41	16	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	41	17	in	in	IN
cord-011327-zsoc4wec	41	18	ICU	ICU	NNP
cord-011327-zsoc4wec	41	19	suggest	suggest	VBP
cord-011327-zsoc4wec	41	20	consideration	consideration	NN
cord-011327-zsoc4wec	41	21	of	of	IN
cord-011327-zsoc4wec	41	22	selective	selective	JJ
cord-011327-zsoc4wec	41	23	digestive	digestive	JJ
cord-011327-zsoc4wec	41	24	decontamination	decontamination	NN
cord-011327-zsoc4wec	41	25	with	with	IN
cord-011327-zsoc4wec	41	26	both	both	CC
cord-011327-zsoc4wec	41	27	topical	topical	JJ
cord-011327-zsoc4wec	41	28	and	and	CC
cord-011327-zsoc4wec	41	29	systemic	systemic	JJ
cord-011327-zsoc4wec	41	30	antibiotics	antibiotic	NNS
cord-011327-zsoc4wec	41	31	(	(	-LRB-
cord-011327-zsoc4wec	41	32	for	for	IN
cord-011327-zsoc4wec	41	33	a	a	DT
cord-011327-zsoc4wec	41	34	maximum	maximum	NN
cord-011327-zsoc4wec	41	35	of	of	IN
cord-011327-zsoc4wec	41	36	96	96	CD
cord-011327-zsoc4wec	41	37	h	h	NN
cord-011327-zsoc4wec	41	38	)	)	-RRB-
cord-011327-zsoc4wec	41	39	to	to	TO
cord-011327-zsoc4wec	41	40	decrease	decrease	VB
cord-011327-zsoc4wec	41	41	the	the	DT
cord-011327-zsoc4wec	41	42	rate	rate	NN
cord-011327-zsoc4wec	41	43	of	of	IN
cord-011327-zsoc4wec	41	44	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	41	45	immediately	immediately	RB
cord-011327-zsoc4wec	41	46	after	after	IN
cord-011327-zsoc4wec	41	47	urgent	urgent	JJ
cord-011327-zsoc4wec	41	48	intubation	intubation	NN
cord-011327-zsoc4wec	41	49	based	base	VBN
cord-011327-zsoc4wec	41	50	on	on	IN
cord-011327-zsoc4wec	41	51	indirect	indirect	JJ
cord-011327-zsoc4wec	41	52	evidence	evidence	NN
cord-011327-zsoc4wec	41	53	from	from	IN
cord-011327-zsoc4wec	41	54	several	several	JJ
cord-011327-zsoc4wec	41	55	studies	study	NNS
cord-011327-zsoc4wec	41	56	[	[	-LRB-
cord-011327-zsoc4wec	41	57	22	22	CD
cord-011327-zsoc4wec	41	58	]	]	-RRB-
cord-011327-zsoc4wec	41	59	.	.	.
cord-011327-zsoc4wec	42	1	Sirvent	Sirvent	NNP
cord-011327-zsoc4wec	42	2	et	et	NNP
cord-011327-zsoc4wec	42	3	al	al	NNP
cord-011327-zsoc4wec	42	4	.	.	.
cord-011327-zsoc4wec	43	1	randomised	randomised	JJ
cord-011327-zsoc4wec	43	2	100	100	CD
cord-011327-zsoc4wec	43	3	comatose	comatose	JJ
cord-011327-zsoc4wec	43	4	patients	patient	NNS
cord-011327-zsoc4wec	43	5	undergoing	undergo	VBG
cord-011327-zsoc4wec	43	6	intubation	intubation	NN
cord-011327-zsoc4wec	43	7	to	to	IN
cord-011327-zsoc4wec	43	8	2	2	CD
cord-011327-zsoc4wec	43	9	doses	dose	NNS
cord-011327-zsoc4wec	43	10	of	of	IN
cord-011327-zsoc4wec	43	11	cefuroxime	cefuroxime	NNP
cord-011327-zsoc4wec	43	12	versus	versus	IN
cord-011327-zsoc4wec	43	13	no	no	DT
cord-011327-zsoc4wec	43	14	treatment	treatment	NN
cord-011327-zsoc4wec	43	15	.	.	.
cord-011327-zsoc4wec	44	1	Patients	patient	NNS
cord-011327-zsoc4wec	44	2	receiving	receive	VBG
cord-011327-zsoc4wec	44	3	cefuroxime	cefuroxime	NNP
cord-011327-zsoc4wec	44	4	had	have	VBD
cord-011327-zsoc4wec	44	5	a	a	DT
cord-011327-zsoc4wec	44	6	lower	low	JJR
cord-011327-zsoc4wec	44	7	rate	rate	NN
cord-011327-zsoc4wec	44	8	of	of	IN
cord-011327-zsoc4wec	44	9	ventilator	ventilator	NN
cord-011327-zsoc4wec	44	10	-	-	HYPH
cord-011327-zsoc4wec	44	11	associated	associate	VBN
cord-011327-zsoc4wec	44	12	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	44	13	(	(	-LRB-
cord-011327-zsoc4wec	44	14	VAP	VAP	NNP
cord-011327-zsoc4wec	44	15	)	)	-RRB-
cord-011327-zsoc4wec	44	16	briefer	briefer	NNP
cord-011327-zsoc4wec	44	17	hospital	hospital	NN
cord-011327-zsoc4wec	44	18	and	and	CC
cord-011327-zsoc4wec	44	19	ICU	ICU	NNP
cord-011327-zsoc4wec	44	20	length	length	NN
cord-011327-zsoc4wec	44	21	of	of	IN
cord-011327-zsoc4wec	44	22	stay	stay	NN
cord-011327-zsoc4wec	44	23	[	[	-LRB-
cord-011327-zsoc4wec	44	24	23	23	CD
cord-011327-zsoc4wec	44	25	]	]	-RRB-
cord-011327-zsoc4wec	44	26	.	.	.
cord-011327-zsoc4wec	45	1	Aquarolo	Aquarolo	NNP
cord-011327-zsoc4wec	45	2	et	et	NNP
cord-011327-zsoc4wec	45	3	al	al	NNP
cord-011327-zsoc4wec	45	4	.	.	.
cord-011327-zsoc4wec	46	1	randomised	randomised	JJ
cord-011327-zsoc4wec	46	2	38	38	CD
cord-011327-zsoc4wec	46	3	comatose	comatose	JJ
cord-011327-zsoc4wec	46	4	mechanically	mechanically	RB
cord-011327-zsoc4wec	46	5	ventilated	ventilate	VBD
cord-011327-zsoc4wec	46	6	patients	patient	NNS
cord-011327-zsoc4wec	46	7	with	with	IN
cord-011327-zsoc4wec	46	8	brain	brain	NN
cord-011327-zsoc4wec	46	9	injury	injury	NN
cord-011327-zsoc4wec	46	10	to	to	IN
cord-011327-zsoc4wec	46	11	ampicillin	ampicillin	NN
cord-011327-zsoc4wec	46	12	-	-	HYPH
cord-011327-zsoc4wec	46	13	sulbactam	sulbactam	NNP
cord-011327-zsoc4wec	46	14	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	46	15	plus	plus	CC
cord-011327-zsoc4wec	46	16	standard	standard	JJ
cord-011327-zsoc4wec	46	17	treatment	treatment	NN
cord-011327-zsoc4wec	46	18	or	or	CC
cord-011327-zsoc4wec	46	19	standard	standard	JJ
cord-011327-zsoc4wec	46	20	treatment	treatment	NN
cord-011327-zsoc4wec	46	21	alone	alone	RB
cord-011327-zsoc4wec	46	22	and	and	CC
cord-011327-zsoc4wec	46	23	showed	show	VBD
cord-011327-zsoc4wec	46	24	that	that	IN
cord-011327-zsoc4wec	46	25	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	46	26	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	46	27	reduced	reduce	VBD
cord-011327-zsoc4wec	46	28	the	the	DT
cord-011327-zsoc4wec	46	29	occurrence	occurrence	NN
cord-011327-zsoc4wec	46	30	of	of	IN
cord-011327-zsoc4wec	46	31	early	early	JJ
cord-011327-zsoc4wec	46	32	-	-	HYPH
cord-011327-zsoc4wec	46	33	onset	onset	NN
cord-011327-zsoc4wec	46	34	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	46	35	(	(	-LRB-
cord-011327-zsoc4wec	46	36	21	21	CD
cord-011327-zsoc4wec	46	37	%	%	NN
cord-011327-zsoc4wec	46	38	vs	vs	IN
cord-011327-zsoc4wec	46	39	58	58	CD
cord-011327-zsoc4wec	46	40	%	%	NN
cord-011327-zsoc4wec	46	41	,	,	,
cord-011327-zsoc4wec	46	42	P	p	NN
cord-011327-zsoc4wec	46	43	=	=	SYM
cord-011327-zsoc4wec	46	44	0.022	0.022	CD
cord-011327-zsoc4wec	46	45	)	)	-RRB-
cord-011327-zsoc4wec	46	46	.	.	.
cord-011327-zsoc4wec	47	1	[	[	-LRB-
cord-011327-zsoc4wec	47	2	24	24	CD
cord-011327-zsoc4wec	47	3	]	]	-RRB-
cord-011327-zsoc4wec	47	4	.	.	.
cord-011327-zsoc4wec	48	1	Similar	similar	JJ
cord-011327-zsoc4wec	48	2	findings	finding	NNS
cord-011327-zsoc4wec	48	3	have	have	VBP
cord-011327-zsoc4wec	48	4	been	be	VBN
cord-011327-zsoc4wec	48	5	reported	report	VBN
cord-011327-zsoc4wec	48	6	in	in	IN
cord-011327-zsoc4wec	48	7	other	other	JJ
cord-011327-zsoc4wec	48	8	ICU	ICU	NNP
cord-011327-zsoc4wec	48	9	settings	setting	NNS
cord-011327-zsoc4wec	48	10	[	[	-LRB-
cord-011327-zsoc4wec	48	11	25	25	CD
cord-011327-zsoc4wec	48	12	]	]	-RRB-
cord-011327-zsoc4wec	48	13	.	.	.
cord-011327-zsoc4wec	49	1	More	more	RBR
cord-011327-zsoc4wec	49	2	recently	recently	RB
cord-011327-zsoc4wec	49	3	,	,	,
cord-011327-zsoc4wec	49	4	a	a	DT
cord-011327-zsoc4wec	49	5	systematic	systematic	JJ
cord-011327-zsoc4wec	49	6	Table	table	NN
cord-011327-zsoc4wec	49	7	1	1	CD
cord-011327-zsoc4wec	49	8	Factors	factor	NNS
cord-011327-zsoc4wec	49	9	that	that	WDT
cord-011327-zsoc4wec	49	10	should	should	MD
cord-011327-zsoc4wec	49	11	be	be	VB
cord-011327-zsoc4wec	49	12	taken	take	VBN
cord-011327-zsoc4wec	49	13	into	into	IN
cord-011327-zsoc4wec	49	14	account	account	NN
cord-011327-zsoc4wec	49	15	when	when	WRB
cord-011327-zsoc4wec	49	16	determining	determine	VBG
cord-011327-zsoc4wec	49	17	the	the	DT
cord-011327-zsoc4wec	49	18	choice	choice	NN
cord-011327-zsoc4wec	49	19	of	of	IN
cord-011327-zsoc4wec	49	20	an	an	DT
cord-011327-zsoc4wec	49	21	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	49	22	review	review	NN
cord-011327-zsoc4wec	49	23	and	and	CC
cord-011327-zsoc4wec	49	24	meta	meta	NNP
cord-011327-zsoc4wec	49	25	-	-	HYPH
cord-011327-zsoc4wec	49	26	analysis	analysis	NN
cord-011327-zsoc4wec	49	27	reported	report	VBD
cord-011327-zsoc4wec	49	28	that	that	IN
cord-011327-zsoc4wec	49	29	systemic	systemic	JJ
cord-011327-zsoc4wec	49	30	administration	administration	NN
cord-011327-zsoc4wec	49	31	of	of	IN
cord-011327-zsoc4wec	49	32	antibiotics	antibiotic	NNS
cord-011327-zsoc4wec	49	33	for	for	IN
cord-011327-zsoc4wec	49	34	no	no	DT
cord-011327-zsoc4wec	49	35	more	more	JJR
cord-011327-zsoc4wec	49	36	than	than	IN
cord-011327-zsoc4wec	49	37	24	24	CD
cord-011327-zsoc4wec	49	38	h	h	NN
cord-011327-zsoc4wec	49	39	following	follow	VBG
cord-011327-zsoc4wec	49	40	intubation	intubation	NN
cord-011327-zsoc4wec	49	41	did	do	VBD
cord-011327-zsoc4wec	49	42	not	not	RB
cord-011327-zsoc4wec	49	43	affect	affect	VB
cord-011327-zsoc4wec	49	44	mortality	mortality	NN
cord-011327-zsoc4wec	49	45	[	[	-LRB-
cord-011327-zsoc4wec	49	46	relative	relative	JJ
cord-011327-zsoc4wec	49	47	risk	risk	NN
cord-011327-zsoc4wec	49	48	(	(	-LRB-
cord-011327-zsoc4wec	49	49	RR	RR	NNP
cord-011327-zsoc4wec	49	50	)	)	-RRB-
cord-011327-zsoc4wec	49	51	1.03	1.03	CD
cord-011327-zsoc4wec	49	52	;	;	:
cord-011327-zsoc4wec	49	53	95	95	CD
cord-011327-zsoc4wec	49	54	%	%	NN
cord-011327-zsoc4wec	49	55	confidence	confidence	NN
cord-011327-zsoc4wec	49	56	interval	interval	NN
cord-011327-zsoc4wec	49	57	(	(	-LRB-
cord-011327-zsoc4wec	49	58	CI	ci	NN
cord-011327-zsoc4wec	49	59	)	)	-RRB-
cord-011327-zsoc4wec	50	1	0.7	0.7	CD
cord-011327-zsoc4wec	50	2	-	-	SYM
cord-011327-zsoc4wec	50	3	1.53	1.53	CD
cord-011327-zsoc4wec	50	4	]	]	-RRB-
cord-011327-zsoc4wec	50	5	,	,	.
cord-011327-zsoc4wec	51	1	but	but	CC
cord-011327-zsoc4wec	51	2	was	be	VBD
cord-011327-zsoc4wec	51	3	associated	associate	VBN
cord-011327-zsoc4wec	51	4	with	with	IN
cord-011327-zsoc4wec	51	5	a	a	DT
cord-011327-zsoc4wec	51	6	reduction	reduction	NN
cord-011327-zsoc4wec	51	7	in	in	IN
cord-011327-zsoc4wec	51	8	the	the	DT
cord-011327-zsoc4wec	51	9	incidence	incidence	NN
cord-011327-zsoc4wec	51	10	of	of	IN
cord-011327-zsoc4wec	51	11	early	early	JJ
cord-011327-zsoc4wec	51	12	-	-	HYPH
cord-011327-zsoc4wec	51	13	onset	onset	NN
cord-011327-zsoc4wec	51	14	VAP	VAP	NNP
cord-011327-zsoc4wec	51	15	and	and	CC
cord-011327-zsoc4wec	51	16	briefer	brief	JJR
cord-011327-zsoc4wec	51	17	ICU	ICU	NNP
cord-011327-zsoc4wec	51	18	lengths	length	NNS
cord-011327-zsoc4wec	51	19	of	of	IN
cord-011327-zsoc4wec	51	20	stay	stay	VB
cord-011327-zsoc4wec	51	21	[	[	-LRB-
cord-011327-zsoc4wec	51	22	26	26	CD
cord-011327-zsoc4wec	51	23	]	]	-RRB-
cord-011327-zsoc4wec	51	24	.	.	.
cord-011327-zsoc4wec	52	1	The	the	DT
cord-011327-zsoc4wec	52	2	literature	literature	NN
cord-011327-zsoc4wec	52	3	does	do	VBZ
cord-011327-zsoc4wec	52	4	seem	seem	VB
cord-011327-zsoc4wec	52	5	to	to	TO
cord-011327-zsoc4wec	52	6	suggest	suggest	VB
cord-011327-zsoc4wec	52	7	that	that	IN
cord-011327-zsoc4wec	52	8	a	a	DT
cord-011327-zsoc4wec	52	9	short	short	JJ
cord-011327-zsoc4wec	52	10	course	course	NN
cord-011327-zsoc4wec	52	11	of	of	IN
cord-011327-zsoc4wec	52	12	prophylactic	prophylactic	JJ
cord-011327-zsoc4wec	52	13	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	52	14	following	follow	VBG
cord-011327-zsoc4wec	52	15	intubation	intubation	NN
cord-011327-zsoc4wec	52	16	may	may	MD
cord-011327-zsoc4wec	52	17	confer	confer	VB
cord-011327-zsoc4wec	52	18	some	some	DT
cord-011327-zsoc4wec	52	19	benefit	benefit	NN
cord-011327-zsoc4wec	52	20	.	.	.
cord-011327-zsoc4wec	53	1	However	however	RB
cord-011327-zsoc4wec	53	2	,	,	,
cord-011327-zsoc4wec	53	3	this	this	DT
cord-011327-zsoc4wec	53	4	finding	finding	NN
cord-011327-zsoc4wec	53	5	is	be	VBZ
cord-011327-zsoc4wec	53	6	inconsistent	inconsistent	JJ
cord-011327-zsoc4wec	53	7	and	and	CC
cord-011327-zsoc4wec	53	8	if	if	IN
cord-011327-zsoc4wec	53	9	it	-PRON-	PRP
cord-011327-zsoc4wec	53	10	does	do	VBZ
cord-011327-zsoc4wec	53	11	exist	exist	VB
cord-011327-zsoc4wec	53	12	,	,	,
cord-011327-zsoc4wec	53	13	the	the	DT
cord-011327-zsoc4wec	53	14	strength	strength	NN
cord-011327-zsoc4wec	53	15	of	of	IN
cord-011327-zsoc4wec	53	16	this	this	DT
cord-011327-zsoc4wec	53	17	effect	effect	NN
cord-011327-zsoc4wec	53	18	remains	remain	VBZ
cord-011327-zsoc4wec	53	19	to	to	TO
cord-011327-zsoc4wec	53	20	be	be	VB
cord-011327-zsoc4wec	53	21	determined	determine	VBN
cord-011327-zsoc4wec	53	22	.	.	.
cord-011327-zsoc4wec	54	1	At	at	IN
cord-011327-zsoc4wec	54	2	this	this	DT
cord-011327-zsoc4wec	54	3	time	time	NN
cord-011327-zsoc4wec	54	4	,	,	,
cord-011327-zsoc4wec	54	5	the	the	DT
cord-011327-zsoc4wec	54	6	results	result	NNS
cord-011327-zsoc4wec	54	7	of	of	IN
cord-011327-zsoc4wec	54	8	a	a	DT
cord-011327-zsoc4wec	54	9	trial	trial	NN
cord-011327-zsoc4wec	54	10	planned	plan	VBN
cord-011327-zsoc4wec	54	11	to	to	TO
cord-011327-zsoc4wec	54	12	include	include	VB
cord-011327-zsoc4wec	54	13	320	320	CD
cord-011327-zsoc4wec	54	14	patients	patient	NNS
cord-011327-zsoc4wec	54	15	with	with	IN
cord-011327-zsoc4wec	54	16	brain	brain	NN
cord-011327-zsoc4wec	54	17	injury	injury	NN
cord-011327-zsoc4wec	54	18	randomised	randomised	JJ
cord-011327-zsoc4wec	54	19	to	to	IN
cord-011327-zsoc4wec	54	20	either	either	DT
cord-011327-zsoc4wec	54	21	one	one	CD
cord-011327-zsoc4wec	54	22	dose	dose	NN
cord-011327-zsoc4wec	54	23	of	of	IN
cord-011327-zsoc4wec	54	24	ceftriaxone	ceftriaxone	NN
cord-011327-zsoc4wec	54	25	within	within	IN
cord-011327-zsoc4wec	54	26	12	12	CD
cord-011327-zsoc4wec	54	27	h	h	NN
cord-011327-zsoc4wec	54	28	of	of	IN
cord-011327-zsoc4wec	54	29	intubation	intubation	NN
cord-011327-zsoc4wec	54	30	or	or	CC
cord-011327-zsoc4wec	54	31	placebo	placebo	NN
cord-011327-zsoc4wec	54	32	are	be	VBP
cord-011327-zsoc4wec	54	33	expected	expect	VBN
cord-011327-zsoc4wec	54	34	[	[	-LRB-
cord-011327-zsoc4wec	54	35	27	27	CD
cord-011327-zsoc4wec	54	36	]	]	-RRB-
cord-011327-zsoc4wec	54	37	.	.	.
cord-011327-zsoc4wec	55	1	Additional	additional	JJ
cord-011327-zsoc4wec	55	2	multicentre	multicentre	NNP
cord-011327-zsoc4wec	55	3	prospective	prospective	JJ
cord-011327-zsoc4wec	55	4	studies	study	NNS
cord-011327-zsoc4wec	55	5	are	be	VBP
cord-011327-zsoc4wec	55	6	required	require	VBN
cord-011327-zsoc4wec	55	7	.	.	.
cord-011327-zsoc4wec	56	1	Chest	chest	NN
cord-011327-zsoc4wec	56	2	drains	drain	NNS
cord-011327-zsoc4wec	57	1	:	:	:
cord-011327-zsoc4wec	57	2	Placement	placement	NN
cord-011327-zsoc4wec	57	3	of	of	IN
cord-011327-zsoc4wec	57	4	a	a	DT
cord-011327-zsoc4wec	57	5	chest	chest	NN
cord-011327-zsoc4wec	57	6	drain	drain	NN
cord-011327-zsoc4wec	57	7	may	may	MD
cord-011327-zsoc4wec	57	8	theoretically	theoretically	RB
cord-011327-zsoc4wec	57	9	be	be	VB
cord-011327-zsoc4wec	57	10	accompanied	accompany	VBN
cord-011327-zsoc4wec	57	11	by	by	IN
cord-011327-zsoc4wec	57	12	bacteraemia	bacteraemia	NNP
cord-011327-zsoc4wec	57	13	,	,	,
cord-011327-zsoc4wec	57	14	particularly	particularly	RB
cord-011327-zsoc4wec	57	15	if	if	IN
cord-011327-zsoc4wec	57	16	placed	place	VBN
cord-011327-zsoc4wec	57	17	in	in	IN
cord-011327-zsoc4wec	57	18	a	a	DT
cord-011327-zsoc4wec	57	19	source	source	NN
cord-011327-zsoc4wec	57	20	of	of	IN
cord-011327-zsoc4wec	57	21	infection	infection	NN
cord-011327-zsoc4wec	57	22	or	or	CC
cord-011327-zsoc4wec	57	23	nearby	nearby	RB
cord-011327-zsoc4wec	57	24	already	already	RB
cord-011327-zsoc4wec	57	25	infected	infect	VBN
cord-011327-zsoc4wec	57	26	lung	lung	NN
cord-011327-zsoc4wec	57	27	.	.	.
cord-011327-zsoc4wec	58	1	Alternatively	alternatively	RB
cord-011327-zsoc4wec	58	2	,	,	,
cord-011327-zsoc4wec	58	3	the	the	DT
cord-011327-zsoc4wec	58	4	chest	chest	NN
cord-011327-zsoc4wec	58	5	drain	drain	NN
cord-011327-zsoc4wec	58	6	is	be	VBZ
cord-011327-zsoc4wec	58	7	a	a	DT
cord-011327-zsoc4wec	58	8	foreign	foreign	JJ
cord-011327-zsoc4wec	58	9	body	body	NN
cord-011327-zsoc4wec	58	10	which	which	WDT
cord-011327-zsoc4wec	58	11	could	could	MD
cord-011327-zsoc4wec	58	12	theoretically	theoretically	RB
cord-011327-zsoc4wec	58	13	become	become	VB
cord-011327-zsoc4wec	58	14	a	a	DT
cord-011327-zsoc4wec	58	15	source	source	NN
cord-011327-zsoc4wec	58	16	of	of	IN
cord-011327-zsoc4wec	58	17	ascending	ascend	VBG
cord-011327-zsoc4wec	58	18	infection	infection	NN
cord-011327-zsoc4wec	58	19	(	(	-LRB-
cord-011327-zsoc4wec	58	20	i.e.	i.e.	FW
cord-011327-zsoc4wec	58	21	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	58	22	,	,	,
cord-011327-zsoc4wec	58	23	empyema	empyema	NNP
cord-011327-zsoc4wec	58	24	)	)	-RRB-
cord-011327-zsoc4wec	58	25	.	.	.
cord-011327-zsoc4wec	59	1	There	there	EX
cord-011327-zsoc4wec	59	2	are	be	VBP
cord-011327-zsoc4wec	59	3	no	no	DT
cord-011327-zsoc4wec	59	4	recommendations	recommendation	NNS
cord-011327-zsoc4wec	59	5	regarding	regard	VBG
cord-011327-zsoc4wec	59	6	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	59	7	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	59	8	in	in	IN
cord-011327-zsoc4wec	59	9	ICU	ICU	NNP
cord-011327-zsoc4wec	59	10	patients	patient	NNS
cord-011327-zsoc4wec	59	11	requiring	require	VBG
cord-011327-zsoc4wec	59	12	chest	chest	NN
cord-011327-zsoc4wec	59	13	drain	drain	NN
cord-011327-zsoc4wec	59	14	insertion	insertion	NN
cord-011327-zsoc4wec	59	15	.	.	.
cord-011327-zsoc4wec	60	1	A	a	DT
cord-011327-zsoc4wec	60	2	metaanalysis	metaanalysis	NN
cord-011327-zsoc4wec	60	3	of	of	IN
cord-011327-zsoc4wec	60	4	studies	study	NNS
cord-011327-zsoc4wec	60	5	focused	focus	VBN
cord-011327-zsoc4wec	60	6	on	on	IN
cord-011327-zsoc4wec	60	7	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	60	8	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	60	9	for	for	IN
cord-011327-zsoc4wec	60	10	chest	chest	NN
cord-011327-zsoc4wec	60	11	drain	drain	NN
cord-011327-zsoc4wec	60	12	insertion	insertion	NN
cord-011327-zsoc4wec	60	13	in	in	IN
cord-011327-zsoc4wec	60	14	non	non	JJ
cord-011327-zsoc4wec	60	15	-	-	JJ
cord-011327-zsoc4wec	60	16	ICU	icu	JJ
cord-011327-zsoc4wec	60	17	patients	patient	NNS
cord-011327-zsoc4wec	60	18	(	(	-LRB-
cord-011327-zsoc4wec	60	19	i.e.	i.e.	FW
cord-011327-zsoc4wec	60	20	thoracic	thoracic	JJ
cord-011327-zsoc4wec	60	21	injury	injury	NN
cord-011327-zsoc4wec	60	22	)	)	-RRB-
cord-011327-zsoc4wec	60	23	,	,	,
cord-011327-zsoc4wec	60	24	concluded	conclude	VBD
cord-011327-zsoc4wec	60	25	that	that	IN
cord-011327-zsoc4wec	60	26	treatment	treatment	NN
cord-011327-zsoc4wec	60	27	after	after	IN
cord-011327-zsoc4wec	60	28	chest	chest	NN
cord-011327-zsoc4wec	60	29	drain	drain	NN
cord-011327-zsoc4wec	60	30	insertion	insertion	NN
cord-011327-zsoc4wec	60	31	was	be	VBD
cord-011327-zsoc4wec	60	32	significantly	significantly	RB
cord-011327-zsoc4wec	60	33	associated	associate	VBN
cord-011327-zsoc4wec	60	34	with	with	IN
cord-011327-zsoc4wec	60	35	a	a	DT
cord-011327-zsoc4wec	60	36	reduced	reduced	JJ
cord-011327-zsoc4wec	60	37	risk	risk	NN
cord-011327-zsoc4wec	60	38	of	of	IN
cord-011327-zsoc4wec	60	39	empyema	empyema	NNP
cord-011327-zsoc4wec	60	40	(	(	-LRB-
cord-011327-zsoc4wec	60	41	RR	RR	NNP
cord-011327-zsoc4wec	60	42	0.25	0.25	CD
cord-011327-zsoc4wec	60	43	;	;	:
cord-011327-zsoc4wec	60	44	95	95	CD
cord-011327-zsoc4wec	60	45	%	%	NN
cord-011327-zsoc4wec	60	46	CI	CI	NNP
cord-011327-zsoc4wec	60	47	0.13	0.13	CD
cord-011327-zsoc4wec	60	48	-	-	HYPH
cord-011327-zsoc4wec	60	49	0.49	0.49	CD
cord-011327-zsoc4wec	60	50	)	)	-RRB-
cord-011327-zsoc4wec	60	51	and	and	CC
cord-011327-zsoc4wec	60	52	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	60	53	(	(	-LRB-
cord-011327-zsoc4wec	60	54	RR	rr	NN
cord-011327-zsoc4wec	60	55	0.41	0.41	CD
cord-011327-zsoc4wec	60	56	;	;	:
cord-011327-zsoc4wec	60	57	95	95	CD
cord-011327-zsoc4wec	60	58	%	%	NN
cord-011327-zsoc4wec	60	59	CI	CI	NNP
cord-011327-zsoc4wec	60	60	0.24	0.24	CD
cord-011327-zsoc4wec	60	61	-	-	HYPH
cord-011327-zsoc4wec	60	62	0.71	0.71	CD
cord-011327-zsoc4wec	60	63	)	)	-RRB-
cord-011327-zsoc4wec	60	64	when	when	WRB
cord-011327-zsoc4wec	60	65	compared	compare	VBN
cord-011327-zsoc4wec	60	66	with	with	IN
cord-011327-zsoc4wec	60	67	placebo	placebo	NN
cord-011327-zsoc4wec	60	68	alone	alone	RB
cord-011327-zsoc4wec	60	69	[	[	-LRB-
cord-011327-zsoc4wec	60	70	28	28	CD
cord-011327-zsoc4wec	60	71	]	]	-RRB-
cord-011327-zsoc4wec	60	72	.	.	.
cord-011327-zsoc4wec	61	1	This	this	DT
cord-011327-zsoc4wec	61	2	study	study	NN
cord-011327-zsoc4wec	61	3	is	be	VBZ
cord-011327-zsoc4wec	61	4	often	often	RB
cord-011327-zsoc4wec	61	5	quoted	quote	VBN
cord-011327-zsoc4wec	61	6	as	as	IN
cord-011327-zsoc4wec	61	7	a	a	DT
cord-011327-zsoc4wec	61	8	reason	reason	NN
cord-011327-zsoc4wec	61	9	to	to	TO
cord-011327-zsoc4wec	61	10	provide	provide	VB
cord-011327-zsoc4wec	61	11	prophylactic	prophylactic	JJ
cord-011327-zsoc4wec	61	12	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	61	13	treatment	treatment	NN
cord-011327-zsoc4wec	61	14	to	to	IN
cord-011327-zsoc4wec	61	15	patients	patient	NNS
cord-011327-zsoc4wec	61	16	who	who	WP
cord-011327-zsoc4wec	61	17	undergo	undergo	VBP
cord-011327-zsoc4wec	61	18	chest	chest	NN
cord-011327-zsoc4wec	61	19	drain	drain	NN
cord-011327-zsoc4wec	61	20	insertion	insertion	NN
cord-011327-zsoc4wec	61	21	or	or	CC
cord-011327-zsoc4wec	61	22	who	who	WP
cord-011327-zsoc4wec	61	23	have	have	VBP
cord-011327-zsoc4wec	61	24	a	a	DT
cord-011327-zsoc4wec	61	25	chest	chest	NN
cord-011327-zsoc4wec	61	26	drain	drain	NN
cord-011327-zsoc4wec	61	27	in	in	IN
cord-011327-zsoc4wec	61	28	situ	situ	NN
cord-011327-zsoc4wec	61	29	.	.	.
cord-011327-zsoc4wec	62	1	However	however	RB
cord-011327-zsoc4wec	62	2	,	,	,
cord-011327-zsoc4wec	62	3	a	a	DT
cord-011327-zsoc4wec	62	4	trauma	trauma	NN
cord-011327-zsoc4wec	62	5	setting	set	VBG
cord-011327-zsoc4wec	62	6	may	may	MD
cord-011327-zsoc4wec	62	7	differ	differ	VB
cord-011327-zsoc4wec	62	8	in	in	IN
cord-011327-zsoc4wec	62	9	both	both	CC
cord-011327-zsoc4wec	62	10	urgency	urgency	NN
cord-011327-zsoc4wec	62	11	and	and	CC
cord-011327-zsoc4wec	62	12	hygiene	hygiene	NN
cord-011327-zsoc4wec	62	13	conditions	condition	NNS
cord-011327-zsoc4wec	62	14	,	,	,
cord-011327-zsoc4wec	62	15	and	and	CC
cord-011327-zsoc4wec	62	16	young	young	JJ
cord-011327-zsoc4wec	62	17	trauma	trauma	NN
cord-011327-zsoc4wec	62	18	patients	patient	NNS
cord-011327-zsoc4wec	62	19	are	be	VBP
cord-011327-zsoc4wec	62	20	very	very	RB
cord-011327-zsoc4wec	62	21	different	different	JJ
cord-011327-zsoc4wec	62	22	from	from	IN
cord-011327-zsoc4wec	62	23	most	most	JJS
cord-011327-zsoc4wec	62	24	surgical	surgical	JJ
cord-011327-zsoc4wec	62	25	patients	patient	NNS
cord-011327-zsoc4wec	62	26	who	who	WP
cord-011327-zsoc4wec	62	27	are	be	VBP
cord-011327-zsoc4wec	62	28	older	old	JJR
cord-011327-zsoc4wec	62	29	and	and	CC
cord-011327-zsoc4wec	62	30	comorbid	comorbid	JJ
cord-011327-zsoc4wec	62	31	,	,	,
cord-011327-zsoc4wec	62	32	thus	thus	RB
cord-011327-zsoc4wec	62	33	extrapolation	extrapolation	NN
cord-011327-zsoc4wec	62	34	may	may	MD
cord-011327-zsoc4wec	62	35	be	be	VB
cord-011327-zsoc4wec	62	36	inappropriate	inappropriate	JJ
cord-011327-zsoc4wec	62	37	.	.	.
cord-011327-zsoc4wec	63	1	Furthermore	furthermore	RB
cord-011327-zsoc4wec	63	2	,	,	,
cord-011327-zsoc4wec	63	3	the	the	DT
cord-011327-zsoc4wec	63	4	length	length	NN
cord-011327-zsoc4wec	63	5	of	of	IN
cord-011327-zsoc4wec	63	6	required	require	VBN
cord-011327-zsoc4wec	63	7	prophylactic	prophylactic	JJ
cord-011327-zsoc4wec	63	8	treatment	treatment	NN
cord-011327-zsoc4wec	63	9	(	(	-LRB-
cord-011327-zsoc4wec	63	10	if	if	IN
cord-011327-zsoc4wec	63	11	any	any	DT
cord-011327-zsoc4wec	63	12	)	)	-RRB-
cord-011327-zsoc4wec	63	13	also	also	RB
cord-011327-zsoc4wec	63	14	remains	remain	VBZ
cord-011327-zsoc4wec	63	15	unclear	unclear	JJ
cord-011327-zsoc4wec	63	16	.	.	.
cord-011327-zsoc4wec	64	1	This	this	DT
cord-011327-zsoc4wec	64	2	question	question	NN
cord-011327-zsoc4wec	64	3	is	be	VBZ
cord-011327-zsoc4wec	64	4	particularly	particularly	RB
cord-011327-zsoc4wec	64	5	pertinent	pertinent	JJ
cord-011327-zsoc4wec	64	6	in	in	IN
cord-011327-zsoc4wec	64	7	patients	patient	NNS
cord-011327-zsoc4wec	64	8	that	that	WDT
cord-011327-zsoc4wec	64	9	undergo	undergo	VBP
cord-011327-zsoc4wec	64	10	drain	drain	NN
cord-011327-zsoc4wec	64	11	insertion	insertion	NN
cord-011327-zsoc4wec	64	12	in	in	IN
cord-011327-zsoc4wec	64	13	sterile	sterile	JJ
cord-011327-zsoc4wec	64	14	conditions	condition	NNS
cord-011327-zsoc4wec	64	15	(	(	-LRB-
cord-011327-zsoc4wec	64	16	e.g.	e.g.	RB
cord-011327-zsoc4wec	64	17	during	during	IN
cord-011327-zsoc4wec	64	18	elective	elective	JJ
cord-011327-zsoc4wec	64	19	thoracic	thoracic	JJ
cord-011327-zsoc4wec	64	20	surgery	surgery	NN
cord-011327-zsoc4wec	64	21	)	)	-RRB-
cord-011327-zsoc4wec	64	22	.	.	.
cord-011327-zsoc4wec	65	1	Most	Most	JJS
cord-011327-zsoc4wec	65	2	of	of	IN
cord-011327-zsoc4wec	65	3	these	these	DT
cord-011327-zsoc4wec	65	4	patients	patient	NNS
cord-011327-zsoc4wec	65	5	receive	receive	VBP
cord-011327-zsoc4wec	65	6	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	65	7	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	65	8	before	before	IN
cord-011327-zsoc4wec	65	9	surgery	surgery	NN
cord-011327-zsoc4wec	65	10	in	in	IN
cord-011327-zsoc4wec	65	11	accordance	accordance	NN
cord-011327-zsoc4wec	65	12	with	with	IN
cord-011327-zsoc4wec	65	13	perioperative	perioperative	JJ
cord-011327-zsoc4wec	65	14	guidelines	guideline	NNS
cord-011327-zsoc4wec	65	15	[	[	-LRB-
cord-011327-zsoc4wec	65	16	12	12	CD
cord-011327-zsoc4wec	65	17	]	]	-RRB-
cord-011327-zsoc4wec	65	18	.	.	.
cord-011327-zsoc4wec	66	1	Meta	Meta	NNP
cord-011327-zsoc4wec	66	2	-	-	HYPH
cord-011327-zsoc4wec	66	3	analysis	analysis	NN
cord-011327-zsoc4wec	66	4	of	of	IN
cord-011327-zsoc4wec	66	5	the	the	DT
cord-011327-zsoc4wec	66	6	data	datum	NNS
cord-011327-zsoc4wec	66	7	on	on	IN
cord-011327-zsoc4wec	66	8	this	this	DT
cord-011327-zsoc4wec	66	9	topic	topic	NN
cord-011327-zsoc4wec	66	10	in	in	IN
cord-011327-zsoc4wec	66	11	the	the	DT
cord-011327-zsoc4wec	66	12	literature	literature	NN
cord-011327-zsoc4wec	66	13	suggests	suggest	VBZ
cord-011327-zsoc4wec	66	14	that	that	IN
cord-011327-zsoc4wec	66	15	prolonged	prolong	VBD
cord-011327-zsoc4wec	66	16	postoperative	postoperative	JJ
cord-011327-zsoc4wec	66	17	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	66	18	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	66	19	does	do	VBZ
cord-011327-zsoc4wec	66	20	not	not	RB
cord-011327-zsoc4wec	66	21	reduce	reduce	VB
cord-011327-zsoc4wec	66	22	the	the	DT
cord-011327-zsoc4wec	66	23	number	number	NN
cord-011327-zsoc4wec	66	24	of	of	IN
cord-011327-zsoc4wec	66	25	infectious	infectious	JJ
cord-011327-zsoc4wec	66	26	complications	complication	NNS
cord-011327-zsoc4wec	66	27	related	relate	VBN
cord-011327-zsoc4wec	66	28	to	to	IN
cord-011327-zsoc4wec	66	29	chest	chest	NN
cord-011327-zsoc4wec	66	30	drains	drain	NNS
cord-011327-zsoc4wec	66	31	compared	compare	VBN
cord-011327-zsoc4wec	66	32	with	with	IN
cord-011327-zsoc4wec	66	33	preoperative	preoperative	JJ
cord-011327-zsoc4wec	66	34	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	66	35	only	only	RB
cord-011327-zsoc4wec	66	36	[	[	-LRB-
cord-011327-zsoc4wec	66	37	29	29	CD
cord-011327-zsoc4wec	66	38	]	]	-RRB-
cord-011327-zsoc4wec	66	39	.	.	.
cord-011327-zsoc4wec	67	1	Cerebral	cerebral	JJ
cord-011327-zsoc4wec	67	2	intra	intra	JJ
cord-011327-zsoc4wec	67	3	-	-	JJ
cord-011327-zsoc4wec	67	4	ventricular	ventricular	JJ
cord-011327-zsoc4wec	67	5	drains	drain	NNS
cord-011327-zsoc4wec	67	6	-	-	:
cord-011327-zsoc4wec	67	7	Current	Current	NNP
cord-011327-zsoc4wec	67	8	Neurocritical	Neurocritical	NNP
cord-011327-zsoc4wec	67	9	Care	Care	NNP
cord-011327-zsoc4wec	67	10	Society	Society	NNP
cord-011327-zsoc4wec	67	11	recommendations	recommendation	NNS
cord-011327-zsoc4wec	67	12	suggest	suggest	VBP
cord-011327-zsoc4wec	67	13	that	that	IN
cord-011327-zsoc4wec	67	14	one	one	CD
cord-011327-zsoc4wec	67	15	dose	dose	NN
cord-011327-zsoc4wec	67	16	of	of	IN
cord-011327-zsoc4wec	67	17	antimicrobials	antimicrobial	NNS
cord-011327-zsoc4wec	67	18	be	be	VB
cord-011327-zsoc4wec	67	19	administered	administer	VBN
cord-011327-zsoc4wec	67	20	prior	prior	RB
cord-011327-zsoc4wec	67	21	to	to	IN
cord-011327-zsoc4wec	67	22	insertion	insertion	NN
cord-011327-zsoc4wec	67	23	of	of	IN
cord-011327-zsoc4wec	67	24	an	an	DT
cord-011327-zsoc4wec	67	25	external	external	JJ
cord-011327-zsoc4wec	67	26	ventricular	ventricular	JJ
cord-011327-zsoc4wec	67	27	drain	drain	NN
cord-011327-zsoc4wec	67	28	.	.	.
cord-011327-zsoc4wec	68	1	This	this	DT
cord-011327-zsoc4wec	68	2	recommendation	recommendation	NN
cord-011327-zsoc4wec	68	3	is	be	VBZ
cord-011327-zsoc4wec	68	4	based	base	VBN
cord-011327-zsoc4wec	68	5	on	on	IN
cord-011327-zsoc4wec	68	6	a	a	DT
cord-011327-zsoc4wec	68	7	weak	weak	JJ
cord-011327-zsoc4wec	68	8	level	level	NN
cord-011327-zsoc4wec	68	9	of	of	IN
cord-011327-zsoc4wec	68	10	evidence	evidence	NN
cord-011327-zsoc4wec	68	11	[	[	-LRB-
cord-011327-zsoc4wec	68	12	30	30	CD
cord-011327-zsoc4wec	68	13	]	]	-RRB-
cord-011327-zsoc4wec	68	14	.	.	.
cord-011327-zsoc4wec	69	1	In	in	IN
cord-011327-zsoc4wec	69	2	conclusion	conclusion	NN
cord-011327-zsoc4wec	69	3	,	,	,
cord-011327-zsoc4wec	69	4	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	69	5	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	69	6	constitutes	constitute	VBZ
cord-011327-zsoc4wec	69	7	a	a	DT
cord-011327-zsoc4wec	69	8	large	large	JJ
cord-011327-zsoc4wec	69	9	part	part	NN
cord-011327-zsoc4wec	69	10	of	of	IN
cord-011327-zsoc4wec	69	11	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	69	12	prescriptions	prescription	NNS
cord-011327-zsoc4wec	69	13	in	in	IN
cord-011327-zsoc4wec	69	14	the	the	DT
cord-011327-zsoc4wec	69	15	ICU	ICU	NNP
cord-011327-zsoc4wec	69	16	.	.	.
cord-011327-zsoc4wec	70	1	Antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	70	2	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	70	3	could	could	MD
cord-011327-zsoc4wec	70	4	theoretically	theoretically	RB
cord-011327-zsoc4wec	70	5	prevent	prevent	VB
cord-011327-zsoc4wec	70	6	appearance	appearance	NN
cord-011327-zsoc4wec	70	7	of	of	IN
cord-011327-zsoc4wec	70	8	infectious	infectious	JJ
cord-011327-zsoc4wec	70	9	complications	complication	NNS
cord-011327-zsoc4wec	70	10	in	in	IN
cord-011327-zsoc4wec	70	11	critically	critically	RB
cord-011327-zsoc4wec	70	12	ill	ill	JJ
cord-011327-zsoc4wec	70	13	ICU	ICU	NNP
cord-011327-zsoc4wec	70	14	patients	patient	NNS
cord-011327-zsoc4wec	70	15	that	that	WDT
cord-011327-zsoc4wec	70	16	must	must	MD
cord-011327-zsoc4wec	70	17	undergo	undergo	VB
cord-011327-zsoc4wec	70	18	an	an	DT
cord-011327-zsoc4wec	70	19	invasive	invasive	JJ
cord-011327-zsoc4wec	70	20	procedure	procedure	NN
cord-011327-zsoc4wec	70	21	in	in	IN
cord-011327-zsoc4wec	70	22	the	the	DT
cord-011327-zsoc4wec	70	23	ICU	ICU	NNP
cord-011327-zsoc4wec	70	24	or	or	CC
cord-011327-zsoc4wec	70	25	the	the	DT
cord-011327-zsoc4wec	70	26	OR	OR	NNP
cord-011327-zsoc4wec	70	27	.	.	.
cord-011327-zsoc4wec	71	1	On	on	IN
cord-011327-zsoc4wec	71	2	the	the	DT
cord-011327-zsoc4wec	71	3	other	other	JJ
cord-011327-zsoc4wec	71	4	hand	hand	NN
cord-011327-zsoc4wec	71	5	,	,	,
cord-011327-zsoc4wec	71	6	redundant	redundant	JJ
cord-011327-zsoc4wec	71	7	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	71	8	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	71	9	could	could	MD
cord-011327-zsoc4wec	71	10	drive	drive	VB
cord-011327-zsoc4wec	71	11	emergence	emergence	NN
cord-011327-zsoc4wec	71	12	of	of	IN
cord-011327-zsoc4wec	71	13	MDR	MDR	NNP
cord-011327-zsoc4wec	71	14	pathogens	pathogen	NNS
cord-011327-zsoc4wec	71	15	and	and	CC
cord-011327-zsoc4wec	71	16	increase	increase	VB
cord-011327-zsoc4wec	71	17	the	the	DT
cord-011327-zsoc4wec	71	18	rate	rate	NN
cord-011327-zsoc4wec	71	19	of	of	IN
cord-011327-zsoc4wec	71	20	adverse	adverse	JJ
cord-011327-zsoc4wec	71	21	drug	drug	NN
cord-011327-zsoc4wec	71	22	reactions	reaction	NNS
cord-011327-zsoc4wec	71	23	.	.	.
cord-011327-zsoc4wec	72	1	There	there	EX
cord-011327-zsoc4wec	72	2	is	be	VBZ
cord-011327-zsoc4wec	72	3	an	an	DT
cord-011327-zsoc4wec	72	4	urgent	urgent	JJ
cord-011327-zsoc4wec	72	5	need	need	NN
cord-011327-zsoc4wec	72	6	to	to	TO
cord-011327-zsoc4wec	72	7	conduct	conduct	VB
cord-011327-zsoc4wec	72	8	methodologically	methodologically	RB
cord-011327-zsoc4wec	72	9	sound	sound	VB
cord-011327-zsoc4wec	72	10	multicentre	multicentre	NNP
cord-011327-zsoc4wec	72	11	randomised	randomised	JJ
cord-011327-zsoc4wec	72	12	clinical	clinical	JJ
cord-011327-zsoc4wec	72	13	trials	trial	NNS
cord-011327-zsoc4wec	72	14	in	in	IN
cord-011327-zsoc4wec	72	15	the	the	DT
cord-011327-zsoc4wec	72	16	ICU	ICU	NNP
cord-011327-zsoc4wec	72	17	environment	environment	NN
cord-011327-zsoc4wec	72	18	on	on	IN
cord-011327-zsoc4wec	72	19	this	this	DT
cord-011327-zsoc4wec	72	20	topic	topic	NN
cord-011327-zsoc4wec	72	21	;	;	:
cord-011327-zsoc4wec	72	22	the	the	DT
cord-011327-zsoc4wec	72	23	literature	literature	NN
cord-011327-zsoc4wec	72	24	is	be	VBZ
cord-011327-zsoc4wec	72	25	particularly	particularly	RB
cord-011327-zsoc4wec	72	26	poor	poor	JJ
cord-011327-zsoc4wec	72	27	with	with	IN
cord-011327-zsoc4wec	72	28	regards	regard	NNS
cord-011327-zsoc4wec	72	29	to	to	IN
cord-011327-zsoc4wec	72	30	both	both	CC
cord-011327-zsoc4wec	72	31	surgical	surgical	JJ
cord-011327-zsoc4wec	72	32	and	and	CC
cord-011327-zsoc4wec	72	33	non	non	JJ
cord-011327-zsoc4wec	72	34	-	-	JJ
cord-011327-zsoc4wec	72	35	surgical	surgical	JJ
cord-011327-zsoc4wec	72	36	procedures	procedure	NNS
cord-011327-zsoc4wec	72	37	in	in	IN
cord-011327-zsoc4wec	72	38	critically	critically	RB
cord-011327-zsoc4wec	72	39	ill	ill	JJ
cord-011327-zsoc4wec	72	40	patients	patient	NNS
cord-011327-zsoc4wec	72	41	.	.	.
cord-011327-zsoc4wec	73	1	The	the	DT
cord-011327-zsoc4wec	73	2	online	online	JJ
cord-011327-zsoc4wec	73	3	version	version	NN
cord-011327-zsoc4wec	73	4	of	of	IN
cord-011327-zsoc4wec	73	5	this	this	DT
cord-011327-zsoc4wec	73	6	article	article	NN
cord-011327-zsoc4wec	73	7	(	(	-LRB-
cord-011327-zsoc4wec	73	8	https	https	NNP
cord-011327-zsoc4wec	73	9	:	:	:
cord-011327-zsoc4wec	73	10	//doi.org/10.1007	//doi.org/10.1007	.
cord-011327-zsoc4wec	73	11	/	/	SYM
cord-011327-zsoc4wec	73	12	s0013	s0013	NNP
cord-011327-zsoc4wec	73	13	4	4	CD
cord-011327-zsoc4wec	73	14	-	-	HYPH
cord-011327-zsoc4wec	73	15	019	019	CD
cord-011327-zsoc4wec	73	16	-	-	HYPH
cord-011327-zsoc4wec	73	17	05870	05870	CD
cord-011327-zsoc4wec	73	18	-0	-0	NFP
cord-011327-zsoc4wec	73	19	)	)	-RRB-
cord-011327-zsoc4wec	73	20	contains	contain	VBZ
cord-011327-zsoc4wec	73	21	supplementary	supplementary	JJ
cord-011327-zsoc4wec	73	22	material	material	NN
cord-011327-zsoc4wec	73	23	,	,	,
cord-011327-zsoc4wec	73	24	which	which	WDT
cord-011327-zsoc4wec	73	25	is	be	VBZ
cord-011327-zsoc4wec	73	26	available	available	JJ
cord-011327-zsoc4wec	73	27	to	to	IN
cord-011327-zsoc4wec	73	28	authorized	authorize	VBN
cord-011327-zsoc4wec	73	29	users	user	NNS
cord-011327-zsoc4wec	73	30	.	.	.
cord-011327-zsoc4wec	73	31	 	 	_SP
cord-011327-zsoc4wec	74	1	Bloodstream	bloodstream	NN
cord-011327-zsoc4wec	74	2	infections	infection	NNS
cord-011327-zsoc4wec	74	3	caused	cause	VBN
cord-011327-zsoc4wec	74	4	by	by	IN
cord-011327-zsoc4wec	74	5	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	74	6	-	-	HYPH
cord-011327-zsoc4wec	74	7	resistant	resistant	JJ
cord-011327-zsoc4wec	74	8	gram	gram	NN
cord-011327-zsoc4wec	74	9	-	-	HYPH
cord-011327-zsoc4wec	74	10	negative	negative	JJ
cord-011327-zsoc4wec	74	11	bacilli	bacilli	NN
cord-011327-zsoc4wec	74	12	:	:	:
cord-011327-zsoc4wec	74	13	risk	risk	NN
cord-011327-zsoc4wec	74	14	factors	factor	NNS
cord-011327-zsoc4wec	74	15	for	for	IN
cord-011327-zsoc4wec	74	16	mortality	mortality	NN
cord-011327-zsoc4wec	74	17	and	and	CC
cord-011327-zsoc4wec	74	18	impact	impact	NN
cord-011327-zsoc4wec	74	19	of	of	IN
cord-011327-zsoc4wec	74	20	inappropriate	inappropriate	JJ
cord-011327-zsoc4wec	74	21	initial	initial	JJ
cord-011327-zsoc4wec	74	22	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	74	23	therapy	therapy	NN
cord-011327-zsoc4wec	74	24	on	on	IN
cord-011327-zsoc4wec	74	25	outcome	outcome	NN
cord-011327-zsoc4wec	75	1	The	the	DT
cord-011327-zsoc4wec	75	2	influence	influence	NN
cord-011327-zsoc4wec	75	3	of	of	IN
cord-011327-zsoc4wec	75	4	inadequate	inadequate	JJ
cord-011327-zsoc4wec	75	5	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	75	6	treatment	treatment	NN
cord-011327-zsoc4wec	75	7	of	of	IN
cord-011327-zsoc4wec	75	8	bloodstream	bloodstream	NN
cord-011327-zsoc4wec	75	9	infections	infection	NNS
cord-011327-zsoc4wec	75	10	on	on	IN
cord-011327-zsoc4wec	75	11	patient	patient	JJ
cord-011327-zsoc4wec	75	12	outcomes	outcome	NNS
cord-011327-zsoc4wec	75	13	in	in	IN
cord-011327-zsoc4wec	75	14	the	the	DT
cord-011327-zsoc4wec	75	15	ICU	ICU	NNP
cord-011327-zsoc4wec	75	16	setting	set	VBG
cord-011327-zsoc4wec	75	17	Bacterial	bacterial	JJ
cord-011327-zsoc4wec	75	18	contamination	contamination	NN
cord-011327-zsoc4wec	75	19	of	of	IN
cord-011327-zsoc4wec	75	20	inanimate	inanimate	JJ
cord-011327-zsoc4wec	75	21	surfaces	surface	NNS
cord-011327-zsoc4wec	75	22	and	and	CC
cord-011327-zsoc4wec	75	23	equipment	equipment	NN
cord-011327-zsoc4wec	75	24	in	in	IN
cord-011327-zsoc4wec	75	25	the	the	DT
cord-011327-zsoc4wec	75	26	intensive	intensive	JJ
cord-011327-zsoc4wec	75	27	care	care	NN
cord-011327-zsoc4wec	75	28	unit	unit	NN
cord-011327-zsoc4wec	75	29	General	general	JJ
cord-011327-zsoc4wec	75	30	principles	principle	NNS
cord-011327-zsoc4wec	75	31	of	of	IN
cord-011327-zsoc4wec	75	32	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	75	33	therapy	therapy	NN
cord-011327-zsoc4wec	75	34	Cost	cost	NN
cord-011327-zsoc4wec	75	35	-	-	HYPH
cord-011327-zsoc4wec	75	36	effectiveness	effectiveness	NN
cord-011327-zsoc4wec	75	37	analysis	analysis	NN
cord-011327-zsoc4wec	75	38	of	of	IN
cord-011327-zsoc4wec	75	39	implementing	implement	VBG
cord-011327-zsoc4wec	75	40	an	an	DT
cord-011327-zsoc4wec	75	41	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	75	42	stewardship	stewardship	NN
cord-011327-zsoc4wec	75	43	program	program	NN
cord-011327-zsoc4wec	75	44	in	in	IN
cord-011327-zsoc4wec	75	45	critical	critical	JJ
cord-011327-zsoc4wec	75	46	care	care	NN
cord-011327-zsoc4wec	75	47	units	unit	NNS
cord-011327-zsoc4wec	75	48	Clostridium	clostridium	NN
cord-011327-zsoc4wec	75	49	difficile	difficile	NN
cord-011327-zsoc4wec	75	50	and	and	CC
cord-011327-zsoc4wec	75	51	the	the	DT
cord-011327-zsoc4wec	75	52	microbiota	microbiota	NN
cord-011327-zsoc4wec	75	53	Effect	effect	NN
cord-011327-zsoc4wec	75	54	of	of	IN
cord-011327-zsoc4wec	75	55	selective	selective	JJ
cord-011327-zsoc4wec	75	56	decontamination	decontamination	NN
cord-011327-zsoc4wec	75	57	on	on	IN
cord-011327-zsoc4wec	75	58	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	75	59	resistance	resistance	NN
cord-011327-zsoc4wec	75	60	in	in	IN
cord-011327-zsoc4wec	75	61	intensive	intensive	JJ
cord-011327-zsoc4wec	75	62	care	care	NN
cord-011327-zsoc4wec	75	63	units	unit	NNS
cord-011327-zsoc4wec	75	64	:	:	:
cord-011327-zsoc4wec	75	65	a	a	DT
cord-011327-zsoc4wec	75	66	systematic	systematic	JJ
cord-011327-zsoc4wec	75	67	review	review	NN
cord-011327-zsoc4wec	75	68	and	and	CC
cord-011327-zsoc4wec	75	69	meta	meta	NNP
cord-011327-zsoc4wec	75	70	-	-	HYPH
cord-011327-zsoc4wec	75	71	analysis	analysis	NN
cord-011327-zsoc4wec	76	1	Antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	76	2	use	use	NN
cord-011327-zsoc4wec	76	3	in	in	IN
cord-011327-zsoc4wec	76	4	European	european	JJ
cord-011327-zsoc4wec	76	5	acute	acute	JJ
cord-011327-zsoc4wec	76	6	care	care	NN
cord-011327-zsoc4wec	76	7	hospitals	hospital	NNS
cord-011327-zsoc4wec	76	8	:	:	:
cord-011327-zsoc4wec	76	9	results	result	NNS
cord-011327-zsoc4wec	76	10	from	from	IN
cord-011327-zsoc4wec	76	11	the	the	DT
cord-011327-zsoc4wec	76	12	second	second	JJ
cord-011327-zsoc4wec	76	13	point	point	NN
cord-011327-zsoc4wec	76	14	prevalence	prevalence	NN
cord-011327-zsoc4wec	76	15	survey	survey	NN
cord-011327-zsoc4wec	76	16	(	(	-LRB-
cord-011327-zsoc4wec	76	17	PPS	PPS	NNP
cord-011327-zsoc4wec	76	18	)	)	-RRB-
cord-011327-zsoc4wec	76	19	of	of	IN
cord-011327-zsoc4wec	76	20	healthcare	healthcare	NN
cord-011327-zsoc4wec	76	21	-	-	HYPH
cord-011327-zsoc4wec	76	22	associated	associate	VBN
cord-011327-zsoc4wec	76	23	infections	infection	NNS
cord-011327-zsoc4wec	76	24	and	and	CC
cord-011327-zsoc4wec	76	25	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	76	26	use	use	NN
cord-011327-zsoc4wec	76	27	ESICM	ESICM	NNP
cord-011327-zsoc4wec	76	28	/	/	SYM
cord-011327-zsoc4wec	76	29	ESC	ESC	NNP
cord-011327-zsoc4wec	76	30	-	-	HYPH
cord-011327-zsoc4wec	76	31	MID	MID	NNP
cord-011327-zsoc4wec	76	32	task	task	NN
cord-011327-zsoc4wec	76	33	force	force	NN
cord-011327-zsoc4wec	76	34	on	on	IN
cord-011327-zsoc4wec	76	35	practical	practical	JJ
cord-011327-zsoc4wec	76	36	management	management	NN
cord-011327-zsoc4wec	76	37	of	of	IN
cord-011327-zsoc4wec	76	38	invasive	invasive	JJ
cord-011327-zsoc4wec	76	39	candidiasis	candidiasi	NNS
cord-011327-zsoc4wec	76	40	in	in	IN
cord-011327-zsoc4wec	76	41	critically	critically	RB
cord-011327-zsoc4wec	76	42	ill	ill	JJ
cord-011327-zsoc4wec	76	43	patients	patient	NNS
cord-011327-zsoc4wec	76	44	Timing	time	VBG
cord-011327-zsoc4wec	76	45	of	of	IN
cord-011327-zsoc4wec	76	46	surgical	surgical	JJ
cord-011327-zsoc4wec	76	47	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	76	48	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	76	49	:	:	:
cord-011327-zsoc4wec	76	50	a	a	DT
cord-011327-zsoc4wec	76	51	phase	phase	NN
cord-011327-zsoc4wec	76	52	3	3	CD
cord-011327-zsoc4wec	76	53	randomised	randomised	JJ
cord-011327-zsoc4wec	76	54	controlled	control	VBN
cord-011327-zsoc4wec	76	55	trial	trial	NN
cord-011327-zsoc4wec	76	56	Antibioprophylaxis	Antibioprophylaxis	NNP
cord-011327-zsoc4wec	76	57	in	in	IN
cord-011327-zsoc4wec	76	58	surgery	surgery	NN
cord-011327-zsoc4wec	76	59	and	and	CC
cord-011327-zsoc4wec	76	60	interventional	interventional	JJ
cord-011327-zsoc4wec	76	61	medicine	medicine	NN
cord-011327-zsoc4wec	77	1	A	a	DT
cord-011327-zsoc4wec	77	2	complete	complete	JJ
cord-011327-zsoc4wec	77	3	and	and	CC
cord-011327-zsoc4wec	77	4	multifaceted	multifaceted	JJ
cord-011327-zsoc4wec	77	5	overview	overview	NN
cord-011327-zsoc4wec	77	6	of	of	IN
cord-011327-zsoc4wec	77	7	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	77	8	use	use	NN
cord-011327-zsoc4wec	77	9	and	and	CC
cord-011327-zsoc4wec	77	10	infection	infection	NN
cord-011327-zsoc4wec	77	11	diagnosis	diagnosis	NN
cord-011327-zsoc4wec	77	12	in	in	IN
cord-011327-zsoc4wec	77	13	the	the	DT
cord-011327-zsoc4wec	77	14	intensive	intensive	JJ
cord-011327-zsoc4wec	77	15	care	care	NN
cord-011327-zsoc4wec	77	16	unit	unit	NN
cord-011327-zsoc4wec	77	17	:	:	:
cord-011327-zsoc4wec	77	18	results	result	NNS
cord-011327-zsoc4wec	77	19	from	from	IN
cord-011327-zsoc4wec	77	20	a	a	DT
cord-011327-zsoc4wec	77	21	prospective	prospective	JJ
cord-011327-zsoc4wec	77	22	four	four	CD
cord-011327-zsoc4wec	77	23	-	-	HYPH
cord-011327-zsoc4wec	77	24	year	year	NN
cord-011327-zsoc4wec	77	25	registration	registration	NN
cord-011327-zsoc4wec	77	26	A	a	DT
cord-011327-zsoc4wec	77	27	nationwide	nationwide	JJ
cord-011327-zsoc4wec	77	28	survey	survey	NN
cord-011327-zsoc4wec	77	29	of	of	IN
cord-011327-zsoc4wec	77	30	intravenous	intravenous	JJ
cord-011327-zsoc4wec	77	31	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	77	32	use	use	NN
cord-011327-zsoc4wec	77	33	in	in	IN
cord-011327-zsoc4wec	77	34	intensive	intensive	JJ
cord-011327-zsoc4wec	77	35	care	care	NN
cord-011327-zsoc4wec	77	36	units	unit	NNS
cord-011327-zsoc4wec	77	37	in	in	IN
cord-011327-zsoc4wec	77	38	Japan	Japan	NNP
cord-011327-zsoc4wec	77	39	Clinical	Clinical	NNP
cord-011327-zsoc4wec	77	40	practice	practice	NN
cord-011327-zsoc4wec	77	41	guidelines	guideline	NNS
cord-011327-zsoc4wec	77	42	for	for	IN
cord-011327-zsoc4wec	77	43	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	77	44	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	77	45	in	in	IN
cord-011327-zsoc4wec	77	46	surgery	surgery	NN
cord-011327-zsoc4wec	77	47	Colonization	Colonization	NNP
cord-011327-zsoc4wec	77	48	pressure	pressure	NN
cord-011327-zsoc4wec	77	49	as	as	IN
cord-011327-zsoc4wec	77	50	a	a	DT
cord-011327-zsoc4wec	77	51	risk	risk	NN
cord-011327-zsoc4wec	77	52	factor	factor	NN
cord-011327-zsoc4wec	77	53	of	of	IN
cord-011327-zsoc4wec	77	54	ICU	ICU	NNP
cord-011327-zsoc4wec	77	55	-	-	HYPH
cord-011327-zsoc4wec	77	56	acquired	acquire	VBN
cord-011327-zsoc4wec	77	57	multidrug	multidrug	NN
cord-011327-zsoc4wec	77	58	resistant	resistant	JJ
cord-011327-zsoc4wec	77	59	bacteria	bacteria	NNS
cord-011327-zsoc4wec	77	60	:	:	:
cord-011327-zsoc4wec	77	61	a	a	DT
cord-011327-zsoc4wec	77	62	prospective	prospective	JJ
cord-011327-zsoc4wec	77	63	observational	observational	JJ
cord-011327-zsoc4wec	77	64	study	study	NN
cord-011327-zsoc4wec	77	65	Accuracy	accuracy	NN
cord-011327-zsoc4wec	77	66	of	of	IN
cord-011327-zsoc4wec	77	67	American	American	NNP
cord-011327-zsoc4wec	77	68	Thoracic	Thoracic	NNP
cord-011327-zsoc4wec	77	69	Society	Society	NNP
cord-011327-zsoc4wec	77	70	/	/	SYM
cord-011327-zsoc4wec	77	71	Infectious	Infectious	NNP
cord-011327-zsoc4wec	77	72	Diseases	Diseases	NNPS
cord-011327-zsoc4wec	77	73	Society	Society	NNP
cord-011327-zsoc4wec	77	74	of	of	IN
cord-011327-zsoc4wec	77	75	America	America	NNP
cord-011327-zsoc4wec	77	76	criteria	criterion	NNS
cord-011327-zsoc4wec	77	77	in	in	IN
cord-011327-zsoc4wec	77	78	predicting	predict	VBG
cord-011327-zsoc4wec	77	79	infection	infection	NN
cord-011327-zsoc4wec	77	80	or	or	CC
cord-011327-zsoc4wec	77	81	colonization	colonization	NN
cord-011327-zsoc4wec	77	82	with	with	IN
cord-011327-zsoc4wec	77	83	multidrug	multidrug	NN
cord-011327-zsoc4wec	77	84	-	-	HYPH
cord-011327-zsoc4wec	77	85	resistant	resistant	JJ
cord-011327-zsoc4wec	77	86	bacteria	bacteria	NNS
cord-011327-zsoc4wec	77	87	at	at	IN
cord-011327-zsoc4wec	77	88	intensive	intensive	JJ
cord-011327-zsoc4wec	77	89	-	-	HYPH
cord-011327-zsoc4wec	77	90	care	care	NN
cord-011327-zsoc4wec	77	91	unit	unit	NN
cord-011327-zsoc4wec	77	92	admission	admission	NN
cord-011327-zsoc4wec	78	1	Anesthesia	anesthesia	NN
cord-011327-zsoc4wec	78	2	in	in	IN
cord-011327-zsoc4wec	78	3	patients	patient	NNS
cord-011327-zsoc4wec	78	4	with	with	IN
cord-011327-zsoc4wec	78	5	infectious	infectious	JJ
cord-011327-zsoc4wec	78	6	disease	disease	NN
cord-011327-zsoc4wec	78	7	caused	cause	VBN
cord-011327-zsoc4wec	78	8	by	by	IN
cord-011327-zsoc4wec	78	9	multi	multi	JJ
cord-011327-zsoc4wec	78	10	-	-	JJ
cord-011327-zsoc4wec	78	11	drug	drug	JJ
cord-011327-zsoc4wec	78	12	resistant	resistant	JJ
cord-011327-zsoc4wec	78	13	bacteria	bacteria	NNS
cord-011327-zsoc4wec	78	14	Surgical	surgical	JJ
cord-011327-zsoc4wec	78	15	antimicrobial	antimicrobial	JJ
cord-011327-zsoc4wec	78	16	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	78	17	in	in	IN
cord-011327-zsoc4wec	78	18	intensive	intensive	JJ
cord-011327-zsoc4wec	78	19	care	care	NN
cord-011327-zsoc4wec	78	20	unit	unit	NN
cord-011327-zsoc4wec	78	21	(	(	-LRB-
cord-011327-zsoc4wec	78	22	ICU	ICU	NNP
cord-011327-zsoc4wec	78	23	)	)	-RRB-
cord-011327-zsoc4wec	78	24	patients	patient	NNS
cord-011327-zsoc4wec	78	25	:	:	:
cord-011327-zsoc4wec	78	26	a	a	DT
cord-011327-zsoc4wec	78	27	preliminary	preliminary	JJ
cord-011327-zsoc4wec	78	28	,	,	,
cord-011327-zsoc4wec	78	29	observational	observational	JJ
cord-011327-zsoc4wec	78	30	,	,	,
cord-011327-zsoc4wec	78	31	retrospective	retrospective	JJ
cord-011327-zsoc4wec	78	32	study	study	NN
cord-011327-zsoc4wec	78	33	Management	Management	NNP
cord-011327-zsoc4wec	78	34	of	of	IN
cord-011327-zsoc4wec	78	35	adults	adult	NNS
cord-011327-zsoc4wec	78	36	with	with	IN
cord-011327-zsoc4wec	78	37	hospital	hospital	NN
cord-011327-zsoc4wec	78	38	-	-	HYPH
cord-011327-zsoc4wec	78	39	acquired	acquire	VBN
cord-011327-zsoc4wec	78	40	and	and	CC
cord-011327-zsoc4wec	78	41	ventilator	ventilator	NN
cord-011327-zsoc4wec	78	42	-	-	HYPH
cord-011327-zsoc4wec	78	43	associated	associate	VBN
cord-011327-zsoc4wec	78	44	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	78	45	:	:	:
cord-011327-zsoc4wec	79	1	2016	2016	CD
cord-011327-zsoc4wec	79	2	clinical	clinical	JJ
cord-011327-zsoc4wec	79	3	practice	practice	NN
cord-011327-zsoc4wec	79	4	guidelines	guideline	NNS
cord-011327-zsoc4wec	79	5	by	by	IN
cord-011327-zsoc4wec	79	6	the	the	DT
cord-011327-zsoc4wec	79	7	Infectious	Infectious	NNP
cord-011327-zsoc4wec	79	8	Diseases	Diseases	NNPS
cord-011327-zsoc4wec	79	9	Society	Society	NNP
cord-011327-zsoc4wec	79	10	of	of	IN
cord-011327-zsoc4wec	79	11	America	America	NNP
cord-011327-zsoc4wec	79	12	and	and	CC
cord-011327-zsoc4wec	79	13	the	the	DT
cord-011327-zsoc4wec	79	14	International	International	NNP
cord-011327-zsoc4wec	79	15	ERS	ERS	NNP
cord-011327-zsoc4wec	79	16	/	/	SYM
cord-011327-zsoc4wec	79	17	ESICM/	ESICM/	NNP
cord-011327-zsoc4wec	79	18	ESCMID	ESCMID	NNP
cord-011327-zsoc4wec	79	19	/	/	SYM
cord-011327-zsoc4wec	79	20	ALAT	ALAT	NNP
cord-011327-zsoc4wec	79	21	guidelines	guideline	NNS
cord-011327-zsoc4wec	79	22	for	for	IN
cord-011327-zsoc4wec	79	23	the	the	DT
cord-011327-zsoc4wec	79	24	management	management	NN
cord-011327-zsoc4wec	79	25	of	of	IN
cord-011327-zsoc4wec	79	26	hospital	hospital	NN
cord-011327-zsoc4wec	79	27	-	-	HYPH
cord-011327-zsoc4wec	79	28	acquired	acquire	VBN
cord-011327-zsoc4wec	79	29	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	79	30	and	and	CC
cord-011327-zsoc4wec	79	31	ventilator	ventilator	NN
cord-011327-zsoc4wec	79	32	-	-	HYPH
cord-011327-zsoc4wec	79	33	associated	associate	VBN
cord-011327-zsoc4wec	79	34	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	79	35	Hospital	Hospital	NNP
cord-011327-zsoc4wec	79	36	-	-	HYPH
cord-011327-zsoc4wec	79	37	acquired	acquire	VBN
cord-011327-zsoc4wec	79	38	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	79	39	in	in	IN
cord-011327-zsoc4wec	79	40	ICU	ICU	NNP
cord-011327-zsoc4wec	79	41	Protective	protective	JJ
cord-011327-zsoc4wec	79	42	effect	effect	NN
cord-011327-zsoc4wec	79	43	of	of	IN
cord-011327-zsoc4wec	79	44	intravenously	intravenously	RB
cord-011327-zsoc4wec	79	45	administered	administer	VBN
cord-011327-zsoc4wec	79	46	cefuroxime	cefuroxime	NN
cord-011327-zsoc4wec	79	47	against	against	IN
cord-011327-zsoc4wec	79	48	nosocomial	nosocomial	JJ
cord-011327-zsoc4wec	79	49	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	79	50	in	in	IN
cord-011327-zsoc4wec	79	51	patients	patient	NNS
cord-011327-zsoc4wec	79	52	with	with	IN
cord-011327-zsoc4wec	79	53	structural	structural	JJ
cord-011327-zsoc4wec	79	54	coma	coma	NN
cord-011327-zsoc4wec	79	55	Antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	79	56	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	79	57	of	of	IN
cord-011327-zsoc4wec	79	58	early	early	JJ
cord-011327-zsoc4wec	79	59	onset	onset	NN
cord-011327-zsoc4wec	79	60	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	79	61	in	in	IN
cord-011327-zsoc4wec	79	62	critically	critically	RB
cord-011327-zsoc4wec	79	63	ill	ill	JJ
cord-011327-zsoc4wec	79	64	comatose	comatose	JJ
cord-011327-zsoc4wec	79	65	patients	patient	NNS
cord-011327-zsoc4wec	79	66	.	.	.
cord-011327-zsoc4wec	80	1	A	a	DT
cord-011327-zsoc4wec	80	2	randomized	randomized	JJ
cord-011327-zsoc4wec	80	3	study	study	NN
cord-011327-zsoc4wec	80	4	Efficacy	Efficacy	NNP
cord-011327-zsoc4wec	80	5	of	of	IN
cord-011327-zsoc4wec	80	6	single	single	JJ
cord-011327-zsoc4wec	80	7	-	-	HYPH
cord-011327-zsoc4wec	80	8	dose	dose	NN
cord-011327-zsoc4wec	80	9	antibiotic	antibiotic	NN
cord-011327-zsoc4wec	80	10	against	against	IN
cord-011327-zsoc4wec	80	11	early	early	JJ
cord-011327-zsoc4wec	80	12	-	-	HYPH
cord-011327-zsoc4wec	80	13	onset	onset	NN
cord-011327-zsoc4wec	80	14	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	80	15	in	in	IN
cord-011327-zsoc4wec	80	16	comatose	comatose	JJ
cord-011327-zsoc4wec	80	17	patients	patient	NNS
cord-011327-zsoc4wec	80	18	who	who	WP
cord-011327-zsoc4wec	80	19	are	be	VBP
cord-011327-zsoc4wec	80	20	ventilatedpreventing	ventilatedprevente	VBG
cord-011327-zsoc4wec	80	21	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	80	22	in	in	IN
cord-011327-zsoc4wec	80	23	comatose	comatose	JJ
cord-011327-zsoc4wec	80	24	patients	patient	NNS
cord-011327-zsoc4wec	80	25	Systemic	systemic	JJ
cord-011327-zsoc4wec	80	26	antibiotics	antibiotic	NNS
cord-011327-zsoc4wec	80	27	for	for	IN
cord-011327-zsoc4wec	80	28	preventing	prevent	VBG
cord-011327-zsoc4wec	80	29	ventilator	ventilator	NN
cord-011327-zsoc4wec	80	30	-	-	HYPH
cord-011327-zsoc4wec	80	31	associated	associate	VBN
cord-011327-zsoc4wec	80	32	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	80	33	in	in	IN
cord-011327-zsoc4wec	80	34	comatose	comatose	JJ
cord-011327-zsoc4wec	80	35	patients	patient	NNS
cord-011327-zsoc4wec	80	36	:	:	:
cord-011327-zsoc4wec	80	37	a	a	DT
cord-011327-zsoc4wec	80	38	systematic	systematic	JJ
cord-011327-zsoc4wec	80	39	review	review	NN
cord-011327-zsoc4wec	80	40	and	and	CC
cord-011327-zsoc4wec	80	41	meta	meta	NNP
cord-011327-zsoc4wec	80	42	-	-	HYPH
cord-011327-zsoc4wec	80	43	analysis	analysis	NN
cord-011327-zsoc4wec	80	44	Prevention	Prevention	NNP
cord-011327-zsoc4wec	80	45	of	of	IN
cord-011327-zsoc4wec	80	46	early	early	JJ
cord-011327-zsoc4wec	80	47	ventilation	ventilation	NN
cord-011327-zsoc4wec	80	48	-	-	HYPH
cord-011327-zsoc4wec	80	49	acquired	acquire	VBN
cord-011327-zsoc4wec	80	50	pneumonia	pneumonia	NN
cord-011327-zsoc4wec	80	51	(	(	-LRB-
cord-011327-zsoc4wec	80	52	VAP	VAP	NNP
cord-011327-zsoc4wec	80	53	)	)	-RRB-
cord-011327-zsoc4wec	80	54	in	in	IN
cord-011327-zsoc4wec	80	55	comatose	comatose	JJ
cord-011327-zsoc4wec	80	56	brain	brain	NN
cord-011327-zsoc4wec	80	57	-	-	HYPH
cord-011327-zsoc4wec	80	58	injured	injure	VBN
cord-011327-zsoc4wec	80	59	patients	patient	NNS
cord-011327-zsoc4wec	80	60	by	by	IN
cord-011327-zsoc4wec	80	61	a	a	DT
cord-011327-zsoc4wec	80	62	single	single	JJ
cord-011327-zsoc4wec	80	63	dose	dose	NN
cord-011327-zsoc4wec	80	64	of	of	IN
cord-011327-zsoc4wec	80	65	ceftriaxone	ceftriaxone	NN
cord-011327-zsoc4wec	80	66	:	:	:
cord-011327-zsoc4wec	80	67	PROPHY	PROPHY	NNP
cord-011327-zsoc4wec	80	68	-	-	HYPH
cord-011327-zsoc4wec	80	69	VAP	VAP	NNP
cord-011327-zsoc4wec	80	70	study	study	NN
cord-011327-zsoc4wec	80	71	protocol	protocol	NN
cord-011327-zsoc4wec	80	72	,	,	,
cord-011327-zsoc4wec	80	73	a	a	DT
cord-011327-zsoc4wec	80	74	multicentre	multicentre	NNP
cord-011327-zsoc4wec	80	75	,	,	,
cord-011327-zsoc4wec	80	76	randomised	randomised	JJ
cord-011327-zsoc4wec	80	77	,	,	,
cord-011327-zsoc4wec	80	78	double	double	JJ
cord-011327-zsoc4wec	80	79	-	-	HYPH
cord-011327-zsoc4wec	80	80	blind	blind	JJ
cord-011327-zsoc4wec	80	81	,	,	,
cord-011327-zsoc4wec	80	82	placebo	placebo	NN
cord-011327-zsoc4wec	80	83	-	-	HYPH
cord-011327-zsoc4wec	80	84	controlled	control	VBN
cord-011327-zsoc4wec	80	85	trial	trial	NN
cord-011327-zsoc4wec	80	86	Systematic	systematic	JJ
cord-011327-zsoc4wec	80	87	review	review	NN
cord-011327-zsoc4wec	80	88	and	and	CC
cord-011327-zsoc4wec	80	89	metaanalysis	metaanalysis	NN
cord-011327-zsoc4wec	80	90	of	of	IN
cord-011327-zsoc4wec	80	91	antibiotic	antibiotic	JJ
cord-011327-zsoc4wec	80	92	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	80	93	to	to	TO
cord-011327-zsoc4wec	80	94	prevent	prevent	VB
cord-011327-zsoc4wec	80	95	infections	infection	NNS
cord-011327-zsoc4wec	80	96	from	from	IN
cord-011327-zsoc4wec	80	97	chest	chest	NN
cord-011327-zsoc4wec	80	98	drains	drain	NNS
cord-011327-zsoc4wec	80	99	in	in	IN
cord-011327-zsoc4wec	80	100	blunt	blunt	JJ
cord-011327-zsoc4wec	80	101	and	and	CC
cord-011327-zsoc4wec	80	102	penetrating	penetrating	JJ
cord-011327-zsoc4wec	80	103	thoracic	thoracic	JJ
cord-011327-zsoc4wec	80	104	injuries	injury	NNS
cord-011327-zsoc4wec	80	105	Postoperative	postoperative	JJ
cord-011327-zsoc4wec	80	106	antibacterial	antibacterial	JJ
cord-011327-zsoc4wec	80	107	prophylaxis	prophylaxis	NN
cord-011327-zsoc4wec	80	108	for	for	IN
cord-011327-zsoc4wec	80	109	the	the	DT
cord-011327-zsoc4wec	80	110	prevention	prevention	NN
cord-011327-zsoc4wec	80	111	of	of	IN
cord-011327-zsoc4wec	80	112	infectious	infectious	JJ
cord-011327-zsoc4wec	80	113	complications	complication	NNS
cord-011327-zsoc4wec	80	114	associated	associate	VBN
cord-011327-zsoc4wec	80	115	with	with	IN
cord-011327-zsoc4wec	80	116	tube	tube	NN
cord-011327-zsoc4wec	80	117	thoracostomy	thoracostomy	NN
cord-011327-zsoc4wec	80	118	in	in	IN
cord-011327-zsoc4wec	80	119	patients	patient	NNS
cord-011327-zsoc4wec	80	120	undergoing	undergo	VBG
cord-011327-zsoc4wec	80	121	elective	elective	JJ
cord-011327-zsoc4wec	80	122	general	general	JJ
cord-011327-zsoc4wec	80	123	thoracic	thoracic	JJ
cord-011327-zsoc4wec	80	124	surgery	surgery	NN
cord-011327-zsoc4wec	80	125	:	:	:
cord-011327-zsoc4wec	80	126	a	a	DT
cord-011327-zsoc4wec	80	127	double	double	JJ
cord-011327-zsoc4wec	80	128	-	-	HYPH
cord-011327-zsoc4wec	80	129	blind	blind	JJ
cord-011327-zsoc4wec	80	130	,	,	,
cord-011327-zsoc4wec	80	131	placebo	placebo	NN
cord-011327-zsoc4wec	80	132	-	-	HYPH
cord-011327-zsoc4wec	80	133	controlled	control	VBN
cord-011327-zsoc4wec	80	134	,	,	,
cord-011327-zsoc4wec	80	135	randomized	randomized	JJ
cord-011327-zsoc4wec	80	136	trial	trial	NN
cord-011327-zsoc4wec	80	137	The	the	DT
cord-011327-zsoc4wec	80	138	insertion	insertion	NN
cord-011327-zsoc4wec	80	139	and	and	CC
cord-011327-zsoc4wec	80	140	management	management	NN
cord-011327-zsoc4wec	80	141	of	of	IN
cord-011327-zsoc4wec	80	142	external	external	JJ
cord-011327-zsoc4wec	80	143	ventricular	ventricular	JJ
cord-011327-zsoc4wec	80	144	drains	drain	VBZ
cord-011327-zsoc4wec	80	145	:	:	:
cord-011327-zsoc4wec	80	146	an	an	DT
cord-011327-zsoc4wec	80	147	evidence	evidence	NN
cord-011327-zsoc4wec	80	148	-	-	HYPH
cord-011327-zsoc4wec	80	149	based	base	VBN
cord-011327-zsoc4wec	80	150	consensus	consensus	NN
cord-011327-zsoc4wec	80	151	statement	statement	NN
cord-011327-zsoc4wec	80	152	:	:	:
cord-011327-zsoc4wec	80	153	a	a	DT
cord-011327-zsoc4wec	80	154	statement	statement	NN
cord-011327-zsoc4wec	80	155	for	for	IN
cord-011327-zsoc4wec	80	156	healthcare	healthcare	NN
cord-011327-zsoc4wec	80	157	professionals	professional	NNS
cord-011327-zsoc4wec	80	158	from	from	IN
cord-011327-zsoc4wec	80	159	the	the	DT
cord-011327-zsoc4wec	80	160	Neurocritical	Neurocritical	NNP
cord-011327-zsoc4wec	80	161	Care	Care	NNP
cord-011327-zsoc4wec	80	162	Society	Society	NNP
cord-011327-zsoc4wec	81	1	The	the	DT
cord-011327-zsoc4wec	81	2	work	work	NN
cord-011327-zsoc4wec	81	3	was	be	VBD
cord-011327-zsoc4wec	81	4	funded	fund	VBN
cord-011327-zsoc4wec	81	5	by	by	IN
cord-011327-zsoc4wec	81	6	JPIAMR	JPIAMR	NNP
cord-011327-zsoc4wec	82	1	(	(	-LRB-
cord-011327-zsoc4wec	82	2	Grant	Grant	NNP
cord-011327-zsoc4wec	82	3	No	No	NNP
cord-011327-zsoc4wec	82	4	.	.	NN
cord-011327-zsoc4wec	82	5	2018	2018	CD
cord-011327-zsoc4wec	82	6	-	-	SYM
cord-011327-zsoc4wec	82	7	06335	06335	CD
cord-011327-zsoc4wec	82	8	)	)	-RRB-
cord-011327-zsoc4wec	82	9	.	.	.
cord-011327-zsoc4wec	82	10	 	 	_SP
cord-011327-zsoc4wec	83	1	Springer	Springer	NNP
cord-011327-zsoc4wec	83	2	Nature	Nature	NNP
cord-011327-zsoc4wec	83	3	remains	remain	VBZ
cord-011327-zsoc4wec	83	4	neutral	neutral	JJ
cord-011327-zsoc4wec	83	5	with	with	IN
cord-011327-zsoc4wec	83	6	regard	regard	NN
cord-011327-zsoc4wec	83	7	to	to	IN
cord-011327-zsoc4wec	83	8	jurisdictional	jurisdictional	JJ
cord-011327-zsoc4wec	83	9	claims	claim	NNS
cord-011327-zsoc4wec	83	10	in	in	IN
cord-011327-zsoc4wec	83	11	published	publish	VBN
cord-011327-zsoc4wec	83	12	maps	map	NNS
cord-011327-zsoc4wec	83	13	and	and	CC
cord-011327-zsoc4wec	83	14	institutional	institutional	JJ
cord-011327-zsoc4wec	83	15	affiliations	affiliation	NNS
cord-011327-zsoc4wec	83	16	.	.	.