id author title date pages extension mime words sentences flesch summary cache txt cord-007664-c5snhymz Mauerhoff, Thekla Differential expression and regulation of major histocompatibility complex (MHC) products in neural and glial cells of the human fetal brain 2002-11-13 .txt text/plain 4673 212 51 To gain an insight into the regulation of HLA in the different cell types in the CNS and to compare it to that observed in the endocrine organs, we have studied the effect of the lympho/monokines interferon (IFN)-α and -γ, tumour necrosis factor (TNF)-α, and interleukin (IL)-2 and other agents on this aspect of the biology of human fetal brain cells in culture. It has previously been reported that primary cultures of human fetal brain tissue can be a useful substrate for studying the expression of cell type-specific antigens, e.g. gangliosides, tetanus toxin receptors (Dickson et al., 1982 (Dickson et al., , 1985 , and the present data confirm that they can also be successfully employed to investigate the expression and modulation of HLA molecules. ./cache/cord-007664-c5snhymz.txt ./txt/cord-007664-c5snhymz.txt