id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-023585-n3lr9z3u	Phillpotts, Robert	Interferon prophylaxis of the common cold	2003-01-06		.txt	text/plain	1970	116	55	Robert Phillpotts describes the mechanism of interferon action and the future hopes and developments for its use in preventing colds. l~'obert Phillpotts describe~ the mechanism of interferon action and the future hopes and developments for its use in preventing colds. Interferon appears to be the ideal antiviral drug for use in preventing colds; it is extremely potent, and active against a wide range of viruses. intranasal interferon prevents colds In an initial experiment at the Common Cold Unit in Wiltshire, UK, intranasal administration of partially purified human leucocyte interferon to volunteers was shown to prevent colds caused by rhinovirus type 4 (Ref. 5). This question was answered in a further experiment carried out in 1982, in which HulFN a, purified to virtual homogeneity on a monoclonal antibody affinity column was shown to prevent colds caused by another rhinovirus, type 9 (Ref. 6).	./cache/cord-023585-n3lr9z3u.txt	./txt/cord-023585-n3lr9z3u.txt