id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-299949-kmn53e2z	Schultz, Kimberly L.W.	Immune Responses to Viruses in the CNS	2016-05-09		.txt	text/plain	6946	349	41	For recovery from infection, the immune response in the central nervous system (CNS) must eliminate or control virus replication without destroying nonrenewable, essential cells. For recovery after virus infection of the central nervous system (CNS), the essential, nonrenewable nature of neurons requires a fine-tuned immune response that controls virus replication without damaging neuronal function. Detailed studies of immune responses to neurotropic viruses have included neuronal infections with rabies virus, flaviviruses, and alphaviruses, as well as infection of multiple cell types with natural mouse pathogens such as Theiler's murine encephalomyelitis virus (TMEV), mouse hepatitis virus (MHV), and lymphocytic choriomeningitis virus (LCMV). Resident cells in the nervous system, including neurons, play an active role in the immune response (Schultz et al., 2014; O'Donnell et al., 2012; Chakraborty et al., 2010; Daffis et al., 2008a; Castorena et al., 2008; Daffis et al., 2007; Commonly used in mouse models of viral encephalitis.	./cache/cord-299949-kmn53e2z.txt	./txt/cord-299949-kmn53e2z.txt