id author title date pages extension mime words sentences flesch summary cache txt cord-347200-dtwhd6zy Ivanova, Daria NK Cells in Mucosal Defense against Infection 2014-08-14 .txt text/plain 6955 369 49 Mucosal NK cells play a pivotal role in early protection through their cytolytic function and IFNγ production against bacteria, fungi, viruses, and parasitic infections. Since NK precursors and other ILC populations in secondary lymphoid tissues express varying levels of this integrin, it may be possible that an NK-DC interaction is a requirement for immature NK cells to be signaled to home to mucosal sites. During mucosal infections of humans and mice, NK cells are recruited to sites of infection and play an important role in immune defense [6, 48] . Therefore the cytokine milieu present in the different mucosal tissues in addition to activating signals stimulated that by diverse pathogens help NK cells respond to infection. NK cells in humans are also important for innate control of gut mucosal infections. During infection, resident mucosal tissue NK cells respond primarily through IFN production, which contributes directly to early control of pathogens. ./cache/cord-347200-dtwhd6zy.txt ./txt/cord-347200-dtwhd6zy.txt