id	sid	tid	token	lemma	pos
cord-003614-63rzzos3	1	1	key	key	NN
cord-003614-63rzzos3	1	2	:	:	:
cord-003614-63rzzos3	2	1	cord-003614	cord-003614	NNP
cord-003614-63rzzos3	2	2	-	-	HYPH
cord-003614-63rzzos3	2	3	63rzzos3	63rzzos3	CD
cord-003614-63rzzos3	2	4	authors	author	NNS
cord-003614-63rzzos3	2	5	:	:	:
cord-003614-63rzzos3	2	6	Klotz	Klotz	NNP
cord-003614-63rzzos3	2	7	,	,	,
cord-003614-63rzzos3	2	8	Daniela	Daniela	NNP
cord-003614-63rzzos3	2	9	;	;	:
cord-003614-63rzzos3	2	10	Gerhauser	Gerhauser	NNP
cord-003614-63rzzos3	2	11	,	,	,
cord-003614-63rzzos3	3	1	Ingo	Ingo	NNP
cord-003614-63rzzos3	3	2	title	title	NN
cord-003614-63rzzos3	3	3	:	:	:
cord-003614-63rzzos3	4	1	Interferon	interferon	NN
cord-003614-63rzzos3	4	2	-	-	HYPH
cord-003614-63rzzos3	4	3	Stimulated	stimulate	VBN
cord-003614-63rzzos3	4	4	Genes	Genes	NNPS
cord-003614-63rzzos3	4	5	—	—	:
cord-003614-63rzzos3	4	6	Mediators	mediator	NNS
cord-003614-63rzzos3	4	7	of	of	IN
cord-003614-63rzzos3	4	8	the	the	DT
cord-003614-63rzzos3	4	9	Innate	Innate	NNP
cord-003614-63rzzos3	4	10	Immune	Immune	NNP
cord-003614-63rzzos3	4	11	Response	Response	NNP
cord-003614-63rzzos3	4	12	during	during	IN
cord-003614-63rzzos3	4	13	Canine	Canine	NNP
cord-003614-63rzzos3	4	14	Distemper	Distemper	NNP
cord-003614-63rzzos3	4	15	Virus	Virus	NNP
cord-003614-63rzzos3	4	16	Infection	infection	NN
cord-003614-63rzzos3	4	17	date	date	NN
cord-003614-63rzzos3	4	18	:	:	:
cord-003614-63rzzos3	4	19	2019	2019	CD
cord-003614-63rzzos3	4	20	-	-	HYPH
cord-003614-63rzzos3	4	21	04	04	CD
cord-003614-63rzzos3	4	22	-	-	HYPH
cord-003614-63rzzos3	4	23	01	01	CD
cord-003614-63rzzos3	4	24	journal	journal	NN
cord-003614-63rzzos3	4	25	:	:	:
cord-003614-63rzzos3	4	26	Int	Int	NNP
cord-003614-63rzzos3	4	27	J	J	NNP
cord-003614-63rzzos3	4	28	Mol	Mol	NNP
cord-003614-63rzzos3	4	29	Sci	Sci	NNP
cord-003614-63rzzos3	4	30	DOI	DOI	NNP
cord-003614-63rzzos3	4	31	:	:	:
cord-003614-63rzzos3	4	32	10.3390	10.3390	CD
cord-003614-63rzzos3	4	33	/	/	SYM
cord-003614-63rzzos3	4	34	ijms20071620	ijms20071620	NN
cord-003614-63rzzos3	4	35	sha	sha	NN
cord-003614-63rzzos3	4	36	:	:	:
cord-003614-63rzzos3	4	37	85657444327cc8301d257fbda39df1a02e9d1d40	85657444327cc8301d257fbda39df1a02e9d1d40	CD
cord-003614-63rzzos3	4	38	doc_id	doc_id	CD
cord-003614-63rzzos3	4	39	:	:	:
cord-003614-63rzzos3	4	40	3614	3614	CD
cord-003614-63rzzos3	4	41	cord_uid	cord_uid	NN
cord-003614-63rzzos3	4	42	:	:	:
cord-003614-63rzzos3	5	1	63rzzos3	63rzzos3	CD
cord-003614-63rzzos3	6	1	The	the	DT
cord-003614-63rzzos3	6	2	demyelinating	demyelinate	VBG
cord-003614-63rzzos3	6	3	canine	canine	JJ
cord-003614-63rzzos3	6	4	distemper	distemper	NN
cord-003614-63rzzos3	6	5	virus	virus	NN
cord-003614-63rzzos3	6	6	(	(	-LRB-
cord-003614-63rzzos3	6	7	CDV)-leukoencephalitis	cdv)-leukoencephalitis	NN
cord-003614-63rzzos3	6	8	represents	represent	VBZ
cord-003614-63rzzos3	6	9	a	a	DT
cord-003614-63rzzos3	6	10	translational	translational	JJ
cord-003614-63rzzos3	6	11	animal	animal	NN
cord-003614-63rzzos3	6	12	model	model	NN
cord-003614-63rzzos3	6	13	for	for	IN
cord-003614-63rzzos3	6	14	multiple	multiple	JJ
cord-003614-63rzzos3	6	15	sclerosis	sclerosis	NN
cord-003614-63rzzos3	6	16	.	.	.
cord-003614-63rzzos3	7	1	The	the	DT
cord-003614-63rzzos3	7	2	present	present	JJ
cord-003614-63rzzos3	7	3	study	study	NN
cord-003614-63rzzos3	7	4	investigated	investigate	VBD
cord-003614-63rzzos3	7	5	the	the	DT
cord-003614-63rzzos3	7	6	expression	expression	NN
cord-003614-63rzzos3	7	7	of	of	IN
cord-003614-63rzzos3	7	8	type	type	NN
cord-003614-63rzzos3	8	1	I	-PRON-	PRP
cord-003614-63rzzos3	9	1	interferon	interferon	NNP
cord-003614-63rzzos3	10	1	(	(	-LRB-
cord-003614-63rzzos3	10	2	IFN	IFN	NNP
cord-003614-63rzzos3	10	3	-	-	HYPH
cord-003614-63rzzos3	10	4	I	I	NNP
cord-003614-63rzzos3	10	5	)	)	-RRB-
cord-003614-63rzzos3	10	6	pathway	pathway	NN
cord-003614-63rzzos3	10	7	members	member	NNS
cord-003614-63rzzos3	10	8	in	in	IN
cord-003614-63rzzos3	10	9	CDV	CDV	NNP
cord-003614-63rzzos3	10	10	-	-	HYPH
cord-003614-63rzzos3	10	11	induced	induce	VBN
cord-003614-63rzzos3	10	12	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	10	13	lesions	lesion	NNS
cord-003614-63rzzos3	10	14	to	to	TO
cord-003614-63rzzos3	10	15	gain	gain	VB
cord-003614-63rzzos3	10	16	an	an	DT
cord-003614-63rzzos3	10	17	insight	insight	NN
cord-003614-63rzzos3	10	18	into	into	IN
cord-003614-63rzzos3	10	19	their	-PRON-	PRP$
cord-003614-63rzzos3	10	20	role	role	NN
cord-003614-63rzzos3	10	21	in	in	IN
cord-003614-63rzzos3	10	22	lesion	lesion	NN
cord-003614-63rzzos3	10	23	development	development	NN
cord-003614-63rzzos3	10	24	.	.	.
cord-003614-63rzzos3	11	1	Gene	gene	NN
cord-003614-63rzzos3	11	2	expression	expression	NN
cord-003614-63rzzos3	11	3	of	of	IN
cord-003614-63rzzos3	11	4	110	110	CD
cord-003614-63rzzos3	11	5	manually	manually	RB
cord-003614-63rzzos3	11	6	selected	select	VBN
cord-003614-63rzzos3	11	7	genes	gene	NNS
cord-003614-63rzzos3	11	8	in	in	IN
cord-003614-63rzzos3	11	9	acute	acute	JJ
cord-003614-63rzzos3	11	10	,	,	,
cord-003614-63rzzos3	11	11	subacute	subacute	JJ
cord-003614-63rzzos3	11	12	and	and	CC
cord-003614-63rzzos3	11	13	chronic	chronic	JJ
cord-003614-63rzzos3	11	14	lesions	lesion	NNS
cord-003614-63rzzos3	11	15	was	be	VBD
cord-003614-63rzzos3	11	16	analyzed	analyze	VBN
cord-003614-63rzzos3	11	17	using	use	VBG
cord-003614-63rzzos3	11	18	pre	pre	JJ
cord-003614-63rzzos3	11	19	-	-	JJ
cord-003614-63rzzos3	11	20	existing	existing	JJ
cord-003614-63rzzos3	11	21	microarray	microarray	NN
cord-003614-63rzzos3	11	22	data	datum	NNS
cord-003614-63rzzos3	11	23	.	.	.
cord-003614-63rzzos3	12	1	Interferon	interferon	NN
cord-003614-63rzzos3	12	2	regulatory	regulatory	JJ
cord-003614-63rzzos3	12	3	factor	factor	NN
cord-003614-63rzzos3	12	4	(	(	-LRB-
cord-003614-63rzzos3	12	5	IRF	IRF	NNP
cord-003614-63rzzos3	12	6	)	)	-RRB-
cord-003614-63rzzos3	12	7	3	3	CD
cord-003614-63rzzos3	12	8	,	,	,
cord-003614-63rzzos3	12	9	IRF7	IRF7	NNP
cord-003614-63rzzos3	12	10	,	,	,
cord-003614-63rzzos3	12	11	signal	signal	NN
cord-003614-63rzzos3	12	12	transducer	transducer	NN
cord-003614-63rzzos3	12	13	and	and	CC
cord-003614-63rzzos3	12	14	activator	activator	NN
cord-003614-63rzzos3	12	15	of	of	IN
cord-003614-63rzzos3	12	16	transcription	transcription	NN
cord-003614-63rzzos3	12	17	(	(	-LRB-
cord-003614-63rzzos3	12	18	STAT	stat	NN
cord-003614-63rzzos3	12	19	)	)	-RRB-
cord-003614-63rzzos3	12	20	1	1	CD
cord-003614-63rzzos3	12	21	,	,	,
cord-003614-63rzzos3	12	22	STAT2	STAT2	NNS
cord-003614-63rzzos3	12	23	,	,	,
cord-003614-63rzzos3	12	24	MX	MX	NNP
cord-003614-63rzzos3	12	25	protein	protein	NN
cord-003614-63rzzos3	12	26	,	,	,
cord-003614-63rzzos3	12	27	protein	protein	NN
cord-003614-63rzzos3	12	28	kinase	kinase	NN
cord-003614-63rzzos3	12	29	R	r	NN
cord-003614-63rzzos3	12	30	(	(	-LRB-
cord-003614-63rzzos3	12	31	PKR	PKR	NNP
cord-003614-63rzzos3	12	32	)	)	-RRB-
cord-003614-63rzzos3	12	33	,	,	,
cord-003614-63rzzos3	12	34	2′-5′-oligoadenylate	2′-5′-oligoadenylate	CD
cord-003614-63rzzos3	12	35	synthetase	synthetase	NN
cord-003614-63rzzos3	12	36	(	(	-LRB-
cord-003614-63rzzos3	12	37	OAS	OAS	NNP
cord-003614-63rzzos3	12	38	)	)	-RRB-
cord-003614-63rzzos3	12	39	1	1	CD
cord-003614-63rzzos3	12	40	and	and	CC
cord-003614-63rzzos3	12	41	interferon	interferon	NN
cord-003614-63rzzos3	12	42	-	-	HYPH
cord-003614-63rzzos3	12	43	stimulated	stimulate	VBN
cord-003614-63rzzos3	12	44	gene	gene	NN
cord-003614-63rzzos3	12	45	(	(	-LRB-
cord-003614-63rzzos3	12	46	ISG	ISG	NNP
cord-003614-63rzzos3	12	47	)	)	-RRB-
cord-003614-63rzzos3	13	1	15	15	CD
cord-003614-63rzzos3	13	2	expression	expression	NN
cord-003614-63rzzos3	13	3	were	be	VBD
cord-003614-63rzzos3	13	4	also	also	RB
cord-003614-63rzzos3	13	5	evaluated	evaluate	VBN
cord-003614-63rzzos3	13	6	using	use	VBG
cord-003614-63rzzos3	13	7	immunohistochemistry	immunohistochemistry	NN
cord-003614-63rzzos3	13	8	.	.	.
cord-003614-63rzzos3	14	1	Cellular	cellular	JJ
cord-003614-63rzzos3	14	2	origin	origin	NN
cord-003614-63rzzos3	14	3	of	of	IN
cord-003614-63rzzos3	14	4	STAT1	stat1	NN
cord-003614-63rzzos3	14	5	,	,	,
cord-003614-63rzzos3	14	6	STAT2	STAT2	NNS
cord-003614-63rzzos3	14	7	,	,	,
cord-003614-63rzzos3	14	8	MX	MX	NNP
cord-003614-63rzzos3	14	9	and	and	CC
cord-003614-63rzzos3	14	10	PKR	PKR	NNP
cord-003614-63rzzos3	14	11	were	be	VBD
cord-003614-63rzzos3	14	12	determined	determine	VBN
cord-003614-63rzzos3	14	13	using	use	VBG
cord-003614-63rzzos3	14	14	immunofluorescence	immunofluorescence	NN
cord-003614-63rzzos3	14	15	.	.	.
cord-003614-63rzzos3	15	1	CDV	CDV	NNP
cord-003614-63rzzos3	15	2	infection	infection	NN
cord-003614-63rzzos3	15	3	caused	cause	VBD
cord-003614-63rzzos3	15	4	an	an	DT
cord-003614-63rzzos3	15	5	increased	increase	VBN
cord-003614-63rzzos3	15	6	expression	expression	NN
cord-003614-63rzzos3	15	7	of	of	IN
cord-003614-63rzzos3	15	8	the	the	DT
cord-003614-63rzzos3	15	9	antiviral	antiviral	JJ
cord-003614-63rzzos3	15	10	effector	effector	NN
cord-003614-63rzzos3	15	11	proteins	protein	NNS
cord-003614-63rzzos3	15	12	MX	MX	NNP
cord-003614-63rzzos3	15	13	,	,	,
cord-003614-63rzzos3	15	14	PKR	PKR	NNP
cord-003614-63rzzos3	15	15	,	,	,
cord-003614-63rzzos3	15	16	OAS1	OAS1	NNP
cord-003614-63rzzos3	15	17	and	and	CC
cord-003614-63rzzos3	15	18	ISG15	ISG15	NNP
cord-003614-63rzzos3	15	19	,	,	,
cord-003614-63rzzos3	15	20	which	which	WDT
cord-003614-63rzzos3	15	21	probably	probably	RB
cord-003614-63rzzos3	15	22	contributed	contribute	VBD
cord-003614-63rzzos3	15	23	to	to	IN
cord-003614-63rzzos3	15	24	a	a	DT
cord-003614-63rzzos3	15	25	restricted	restrict	VBN
cord-003614-63rzzos3	15	26	viral	viral	JJ
cord-003614-63rzzos3	15	27	replication	replication	NN
cord-003614-63rzzos3	15	28	,	,	,
cord-003614-63rzzos3	15	29	particularly	particularly	RB
cord-003614-63rzzos3	15	30	in	in	IN
cord-003614-63rzzos3	15	31	neurons	neuron	NNS
cord-003614-63rzzos3	15	32	and	and	CC
cord-003614-63rzzos3	15	33	oligodendrocytes	oligodendrocyte	NNS
cord-003614-63rzzos3	15	34	.	.	.
cord-003614-63rzzos3	16	1	This	this	DT
cord-003614-63rzzos3	16	2	increase	increase	NN
cord-003614-63rzzos3	16	3	might	may	MD
cord-003614-63rzzos3	16	4	be	be	VB
cord-003614-63rzzos3	16	5	partly	partly	RB
cord-003614-63rzzos3	16	6	mediated	mediate	VBN
cord-003614-63rzzos3	16	7	by	by	IN
cord-003614-63rzzos3	16	8	IRF	IRF	NNP
cord-003614-63rzzos3	16	9	-	-	HYPH
cord-003614-63rzzos3	16	10	dependent	dependent	JJ
cord-003614-63rzzos3	16	11	pathways	pathway	NNS
cord-003614-63rzzos3	16	12	due	due	JJ
cord-003614-63rzzos3	16	13	to	to	IN
cord-003614-63rzzos3	16	14	the	the	DT
cord-003614-63rzzos3	16	15	lack	lack	NN
cord-003614-63rzzos3	16	16	of	of	IN
cord-003614-63rzzos3	16	17	changes	change	NNS
cord-003614-63rzzos3	16	18	in	in	IN
cord-003614-63rzzos3	16	19	IFN	IFN	NNP
cord-003614-63rzzos3	16	20	-	-	HYPH
cord-003614-63rzzos3	16	21	I	-PRON-	PRP
cord-003614-63rzzos3	16	22	levels	level	NNS
cord-003614-63rzzos3	16	23	and	and	CC
cord-003614-63rzzos3	16	24	absence	absence	NN
cord-003614-63rzzos3	16	25	of	of	IN
cord-003614-63rzzos3	16	26	STAT2	STAT2	NNS
cord-003614-63rzzos3	16	27	in	in	IN
cord-003614-63rzzos3	16	28	astrocytes	astrocyte	NNS
cord-003614-63rzzos3	16	29	.	.	.
cord-003614-63rzzos3	17	1	Nevertheless	nevertheless	RB
cord-003614-63rzzos3	17	2	,	,	,
cord-003614-63rzzos3	17	3	activated	activate	VBN
cord-003614-63rzzos3	17	4	microglia	microglia	NNS
cord-003614-63rzzos3	17	5	/	/	SYM
cord-003614-63rzzos3	17	6	macrophages	macrophage	NNS
cord-003614-63rzzos3	17	7	showed	show	VBD
cord-003614-63rzzos3	17	8	a	a	DT
cord-003614-63rzzos3	17	9	strong	strong	JJ
cord-003614-63rzzos3	17	10	expression	expression	NN
cord-003614-63rzzos3	17	11	of	of	IN
cord-003614-63rzzos3	17	12	STAT1	stat1	NN
cord-003614-63rzzos3	17	13	,	,	,
cord-003614-63rzzos3	17	14	STAT2	STAT2	NNS
cord-003614-63rzzos3	17	15	and	and	CC
cord-003614-63rzzos3	17	16	MX	MX	NNP
cord-003614-63rzzos3	17	17	proteins	protein	NNS
cord-003614-63rzzos3	17	18	in	in	IN
cord-003614-63rzzos3	17	19	later	later	JJ
cord-003614-63rzzos3	17	20	stages	stage	NNS
cord-003614-63rzzos3	17	21	of	of	IN
cord-003614-63rzzos3	17	22	the	the	DT
cord-003614-63rzzos3	17	23	disease	disease	NN
cord-003614-63rzzos3	17	24	,	,	,
cord-003614-63rzzos3	17	25	indicating	indicate	VBG
cord-003614-63rzzos3	17	26	a	a	DT
cord-003614-63rzzos3	17	27	strong	strong	JJ
cord-003614-63rzzos3	17	28	activation	activation	NN
cord-003614-63rzzos3	17	29	of	of	IN
cord-003614-63rzzos3	17	30	the	the	DT
cord-003614-63rzzos3	17	31	IFN	IFN	NNP
cord-003614-63rzzos3	17	32	-	-	HYPH
cord-003614-63rzzos3	17	33	I	I	NNP
cord-003614-63rzzos3	17	34	signaling	signal	VBG
cord-003614-63rzzos3	17	35	cascade	cascade	NN
cord-003614-63rzzos3	17	36	,	,	,
cord-003614-63rzzos3	17	37	which	which	WDT
cord-003614-63rzzos3	17	38	might	may	MD
cord-003614-63rzzos3	17	39	be	be	VB
cord-003614-63rzzos3	17	40	involved	involve	VBN
cord-003614-63rzzos3	17	41	in	in	IN
cord-003614-63rzzos3	17	42	the	the	DT
cord-003614-63rzzos3	17	43	aggravation	aggravation	NN
cord-003614-63rzzos3	17	44	of	of	IN
cord-003614-63rzzos3	17	45	bystander	bystander	NN
cord-003614-63rzzos3	17	46	demyelination	demyelination	NN
cord-003614-63rzzos3	17	47	.	.	.
cord-003614-63rzzos3	18	1	Canine	canine	JJ
cord-003614-63rzzos3	18	2	distemper	distemper	NN
cord-003614-63rzzos3	18	3	virus	virus	NN
cord-003614-63rzzos3	18	4	(	(	-LRB-
cord-003614-63rzzos3	18	5	CDV	CDV	NNP
cord-003614-63rzzos3	18	6	)	)	-RRB-
cord-003614-63rzzos3	18	7	is	be	VBZ
cord-003614-63rzzos3	18	8	an	an	DT
cord-003614-63rzzos3	18	9	enveloped	envelop	VBN
cord-003614-63rzzos3	18	10	,	,	,
cord-003614-63rzzos3	18	11	single	single	RB
cord-003614-63rzzos3	18	12	-	-	HYPH
cord-003614-63rzzos3	18	13	stranded	stranded	JJ
cord-003614-63rzzos3	18	14	,	,	,
cord-003614-63rzzos3	18	15	negative	negative	JJ
cord-003614-63rzzos3	18	16	-	-	HYPH
cord-003614-63rzzos3	18	17	sense	sense	NN
cord-003614-63rzzos3	18	18	RNA	RNA	NNP
cord-003614-63rzzos3	18	19	virus	virus	NN
cord-003614-63rzzos3	18	20	[	[	-LRB-
cord-003614-63rzzos3	18	21	1	1	CD
cord-003614-63rzzos3	18	22	,	,	,
cord-003614-63rzzos3	18	23	2	2	CD
cord-003614-63rzzos3	18	24	]	]	-RRB-
cord-003614-63rzzos3	18	25	,	,	,
cord-003614-63rzzos3	18	26	which	which	WDT
cord-003614-63rzzos3	18	27	can	can	MD
cord-003614-63rzzos3	18	28	infect	infect	VB
cord-003614-63rzzos3	18	29	terrestrial	terrestrial	JJ
cord-003614-63rzzos3	18	30	and	and	CC
cord-003614-63rzzos3	18	31	aquatic	aquatic	JJ
cord-003614-63rzzos3	18	32	carnivores	carnivore	NNS
cord-003614-63rzzos3	18	33	via	via	IN
cord-003614-63rzzos3	18	34	the	the	DT
cord-003614-63rzzos3	18	35	oropharyngeal	oropharyngeal	JJ
cord-003614-63rzzos3	18	36	route	route	NN
cord-003614-63rzzos3	18	37	[	[	-LRB-
cord-003614-63rzzos3	18	38	3	3	CD
cord-003614-63rzzos3	18	39	,	,	,
cord-003614-63rzzos3	18	40	4	4	CD
cord-003614-63rzzos3	18	41	]	]	-RRB-
cord-003614-63rzzos3	18	42	.	.	.
cord-003614-63rzzos3	19	1	The	the	DT
cord-003614-63rzzos3	19	2	clinical	clinical	JJ
cord-003614-63rzzos3	19	3	course	course	NN
cord-003614-63rzzos3	19	4	of	of	IN
cord-003614-63rzzos3	19	5	the	the	DT
cord-003614-63rzzos3	19	6	disease	disease	NN
cord-003614-63rzzos3	19	7	depends	depend	VBZ
cord-003614-63rzzos3	19	8	on	on	IN
cord-003614-63rzzos3	19	9	the	the	DT
cord-003614-63rzzos3	19	10	CDV	CDV	NNP
cord-003614-63rzzos3	19	11	strain	strain	NN
cord-003614-63rzzos3	19	12	as	as	RB
cord-003614-63rzzos3	19	13	well	well	RB
cord-003614-63rzzos3	19	14	as	as	IN
cord-003614-63rzzos3	19	15	the	the	DT
cord-003614-63rzzos3	19	16	immune	immune	JJ
cord-003614-63rzzos3	19	17	status	status	NN
cord-003614-63rzzos3	19	18	and	and	CC
cord-003614-63rzzos3	19	19	age	age	NN
cord-003614-63rzzos3	19	20	of	of	IN
cord-003614-63rzzos3	19	21	the	the	DT
cord-003614-63rzzos3	19	22	infected	infected	JJ
cord-003614-63rzzos3	19	23	host	host	NN
cord-003614-63rzzos3	19	24	[	[	-LRB-
cord-003614-63rzzos3	19	25	2	2	CD
cord-003614-63rzzos3	19	26	,	,	,
cord-003614-63rzzos3	19	27	4	4	CD
cord-003614-63rzzos3	19	28	]	]	-RRB-
cord-003614-63rzzos3	19	29	.	.	.
cord-003614-63rzzos3	20	1	CDV	CDV	NNP
cord-003614-63rzzos3	20	2	-	-	HYPH
cord-003614-63rzzos3	20	3	infected	infect	VBN
cord-003614-63rzzos3	20	4	animals	animal	NNS
cord-003614-63rzzos3	20	5	can	can	MD
cord-003614-63rzzos3	20	6	either	either	CC
cord-003614-63rzzos3	20	7	trigger	trigger	VB
cord-003614-63rzzos3	20	8	a	a	DT
cord-003614-63rzzos3	20	9	strong	strong	JJ
cord-003614-63rzzos3	20	10	humoral	humoral	JJ
cord-003614-63rzzos3	20	11	and	and	CC
cord-003614-63rzzos3	20	12	cellular	cellular	JJ
cord-003614-63rzzos3	20	13	immune	immune	JJ
cord-003614-63rzzos3	20	14	response	response	NN
cord-003614-63rzzos3	20	15	between	between	IN
cord-003614-63rzzos3	20	16	the	the	DT
cord-003614-63rzzos3	20	17	8th	8th	JJ
cord-003614-63rzzos3	20	18	and	and	CC
cord-003614-63rzzos3	20	19	14th	14th	JJ
cord-003614-63rzzos3	20	20	day	day	NN
cord-003614-63rzzos3	20	21	after	after	IN
cord-003614-63rzzos3	20	22	infection	infection	NN
cord-003614-63rzzos3	20	23	and	and	CC
cord-003614-63rzzos3	20	24	recover	recover	VB
cord-003614-63rzzos3	20	25	or	or	CC
cord-003614-63rzzos3	20	26	,	,	,
cord-003614-63rzzos3	20	27	in	in	IN
cord-003614-63rzzos3	20	28	the	the	DT
cord-003614-63rzzos3	20	29	case	case	NN
cord-003614-63rzzos3	20	30	of	of	IN
cord-003614-63rzzos3	20	31	a	a	DT
cord-003614-63rzzos3	20	32	weak	weak	JJ
cord-003614-63rzzos3	20	33	immune	immune	JJ
cord-003614-63rzzos3	20	34	response	response	NN
cord-003614-63rzzos3	20	35	,	,	,
cord-003614-63rzzos3	20	36	die	die	VB
cord-003614-63rzzos3	20	37	or	or	CC
cord-003614-63rzzos3	20	38	develop	develop	VB
cord-003614-63rzzos3	20	39	a	a	DT
cord-003614-63rzzos3	20	40	persistent	persistent	JJ
cord-003614-63rzzos3	20	41	infection	infection	NN
cord-003614-63rzzos3	20	42	[	[	-LRB-
cord-003614-63rzzos3	20	43	4	4	CD
cord-003614-63rzzos3	20	44	,	,	,
cord-003614-63rzzos3	20	45	5	5	CD
cord-003614-63rzzos3	20	46	]	]	-RRB-
cord-003614-63rzzos3	20	47	.	.	.
cord-003614-63rzzos3	21	1	Clinically	clinically	RB
cord-003614-63rzzos3	21	2	,	,	,
cord-003614-63rzzos3	21	3	canine	canine	JJ
cord-003614-63rzzos3	21	4	distemper	distemper	NN
cord-003614-63rzzos3	21	5	is	be	VBZ
cord-003614-63rzzos3	21	6	predominantly	predominantly	RB
cord-003614-63rzzos3	21	7	characterized	characterize	VBN
cord-003614-63rzzos3	21	8	by	by	IN
cord-003614-63rzzos3	21	9	catarrhal	catarrhal	NN
cord-003614-63rzzos3	21	10	respiratory	respiratory	JJ
cord-003614-63rzzos3	21	11	and	and	CC
cord-003614-63rzzos3	21	12	enteric	enteric	JJ
cord-003614-63rzzos3	21	13	disease	disease	NN
cord-003614-63rzzos3	21	14	signs	sign	NNS
cord-003614-63rzzos3	21	15	,	,	,
cord-003614-63rzzos3	21	16	but	but	CC
cord-003614-63rzzos3	21	17	a	a	DT
cord-003614-63rzzos3	21	18	systemic	systemic	JJ
cord-003614-63rzzos3	21	19	form	form	NN
cord-003614-63rzzos3	21	20	affecting	affect	VBG
cord-003614-63rzzos3	21	21	also	also	RB
cord-003614-63rzzos3	21	22	the	the	DT
cord-003614-63rzzos3	21	23	central	central	JJ
cord-003614-63rzzos3	21	24	nervous	nervous	JJ
cord-003614-63rzzos3	21	25	system	system	NN
cord-003614-63rzzos3	21	26	(	(	-LRB-
cord-003614-63rzzos3	21	27	CNS	CNS	NNP
cord-003614-63rzzos3	21	28	)	)	-RRB-
cord-003614-63rzzos3	21	29	and	and	CC
cord-003614-63rzzos3	21	30	unusual	unusual	JJ
cord-003614-63rzzos3	21	31	manifestations	manifestation	NNS
cord-003614-63rzzos3	21	32	including	include	VBG
cord-003614-63rzzos3	21	33	the	the	DT
cord-003614-63rzzos3	21	34	so	so	RB
cord-003614-63rzzos3	21	35	-	-	HYPH
cord-003614-63rzzos3	21	36	called	call	VBN
cord-003614-63rzzos3	21	37	"	"	``
cord-003614-63rzzos3	21	38	hard	hard	JJ
cord-003614-63rzzos3	21	39	pad	pad	NN
cord-003614-63rzzos3	21	40	"	"	''
cord-003614-63rzzos3	21	41	disease	disease	NN
cord-003614-63rzzos3	21	42	can	can	MD
cord-003614-63rzzos3	21	43	occur	occur	VB
cord-003614-63rzzos3	21	44	[	[	-LRB-
cord-003614-63rzzos3	21	45	4	4	CD
cord-003614-63rzzos3	21	46	]	]	-RRB-
cord-003614-63rzzos3	21	47	.	.	.
cord-003614-63rzzos3	22	1	The	the	DT
cord-003614-63rzzos3	22	2	clinical	clinical	JJ
cord-003614-63rzzos3	22	3	disease	disease	NN
cord-003614-63rzzos3	22	4	of	of	IN
cord-003614-63rzzos3	22	5	canine	canine	JJ
cord-003614-63rzzos3	22	6	distemper	distemper	NN
cord-003614-63rzzos3	22	7	is	be	VBZ
cord-003614-63rzzos3	22	8	similar	similar	JJ
cord-003614-63rzzos3	22	9	in	in	IN
cord-003614-63rzzos3	22	10	pathogenesis	pathogenesis	NN
cord-003614-63rzzos3	22	11	and	and	CC
cord-003614-63rzzos3	22	12	symptoms	symptom	NNS
cord-003614-63rzzos3	22	13	to	to	IN
cord-003614-63rzzos3	22	14	measles	measle	NNS
cord-003614-63rzzos3	22	15	virus	virus	NN
cord-003614-63rzzos3	22	16	infection	infection	NN
cord-003614-63rzzos3	22	17	in	in	IN
cord-003614-63rzzos3	22	18	humans	human	NNS
cord-003614-63rzzos3	22	19	[	[	-LRB-
cord-003614-63rzzos3	22	20	4	4	CD
cord-003614-63rzzos3	22	21	]	]	-RRB-
cord-003614-63rzzos3	22	22	.	.	.
cord-003614-63rzzos3	23	1	Neurologic	neurologic	JJ
cord-003614-63rzzos3	23	2	manifestations	manifestation	NNS
cord-003614-63rzzos3	23	3	of	of	IN
cord-003614-63rzzos3	23	4	canine	canine	JJ
cord-003614-63rzzos3	23	5	distemper	distemper	NN
cord-003614-63rzzos3	23	6	can	can	MD
cord-003614-63rzzos3	23	7	be	be	VB
cord-003614-63rzzos3	23	8	caused	cause	VBN
cord-003614-63rzzos3	23	9	by	by	IN
cord-003614-63rzzos3	23	10	gray	gray	JJ
cord-003614-63rzzos3	23	11	and/or	and/or	CC
cord-003614-63rzzos3	23	12	white	white	JJ
cord-003614-63rzzos3	23	13	matter	matter	NN
cord-003614-63rzzos3	23	14	disease	disease	NN
cord-003614-63rzzos3	23	15	[	[	-LRB-
cord-003614-63rzzos3	23	16	4	4	CD
cord-003614-63rzzos3	23	17	]	]	-RRB-
cord-003614-63rzzos3	23	18	[	[	-LRB-
cord-003614-63rzzos3	23	19	5	5	CD
cord-003614-63rzzos3	23	20	]	]	-RRB-
cord-003614-63rzzos3	23	21	[	[	-LRB-
cord-003614-63rzzos3	23	22	6	6	CD
cord-003614-63rzzos3	23	23	]	]	-RRB-
cord-003614-63rzzos3	23	24	[	[	-LRB-
cord-003614-63rzzos3	23	25	7	7	CD
cord-003614-63rzzos3	23	26	]	]	-RRB-
cord-003614-63rzzos3	23	27	.	.	.
cord-003614-63rzzos3	24	1	The	the	DT
cord-003614-63rzzos3	24	2	rarer	rare	JJR
cord-003614-63rzzos3	24	3	polioencephalitis	polioencephalitis	NN
cord-003614-63rzzos3	24	4	is	be	VBZ
cord-003614-63rzzos3	24	5	divided	divide	VBN
cord-003614-63rzzos3	24	6	into	into	IN
cord-003614-63rzzos3	24	7	"	"	``
cord-003614-63rzzos3	24	8	old	old	JJ
cord-003614-63rzzos3	24	9	dog	dog	NN
cord-003614-63rzzos3	24	10	encephalitis	encephalitis	NN
cord-003614-63rzzos3	24	11	"	"	''
cord-003614-63rzzos3	24	12	,	,	,
cord-003614-63rzzos3	24	13	"	"	''
cord-003614-63rzzos3	24	14	post	post	JJ
cord-003614-63rzzos3	24	15	-	-	JJ
cord-003614-63rzzos3	24	16	vaccination	vaccination	JJ
cord-003614-63rzzos3	24	17	distemper	distemper	NN
cord-003614-63rzzos3	24	18	encephalitis	encephalitis	RB
cord-003614-63rzzos3	24	19	"	"	''
cord-003614-63rzzos3	24	20	and	and	CC
cord-003614-63rzzos3	24	21	"	"	``
cord-003614-63rzzos3	24	22	inclusion	inclusion	NN
cord-003614-63rzzos3	24	23	body	body	NN
cord-003614-63rzzos3	24	24	polioencephalitis	polioencephalitis	NN
cord-003614-63rzzos3	24	25	"	"	''
cord-003614-63rzzos3	24	26	[	[	-LRB-
cord-003614-63rzzos3	24	27	6	6	CD
cord-003614-63rzzos3	24	28	,	,	,
cord-003614-63rzzos3	24	29	7	7	CD
cord-003614-63rzzos3	24	30	]	]	-RRB-
cord-003614-63rzzos3	24	31	.	.	.
cord-003614-63rzzos3	25	1	However	however	RB
cord-003614-63rzzos3	25	2	,	,	,
cord-003614-63rzzos3	25	3	the	the	DT
cord-003614-63rzzos3	25	4	nervous	nervous	JJ
cord-003614-63rzzos3	25	5	form	form	NN
cord-003614-63rzzos3	25	6	usually	usually	RB
cord-003614-63rzzos3	25	7	manifests	manifest	VBZ
cord-003614-63rzzos3	25	8	as	as	IN
cord-003614-63rzzos3	25	9	leukoencephalitis	leukoencephalitis	NNP
cord-003614-63rzzos3	25	10	within	within	IN
cord-003614-63rzzos3	25	11	the	the	DT
cord-003614-63rzzos3	25	12	cerebellum	cerebellum	NN
cord-003614-63rzzos3	25	13	[	[	-LRB-
cord-003614-63rzzos3	25	14	5	5	CD
cord-003614-63rzzos3	25	15	]	]	-RRB-
cord-003614-63rzzos3	25	16	.	.	.
cord-003614-63rzzos3	26	1	The	the	DT
cord-003614-63rzzos3	26	2	lesions	lesion	NNS
cord-003614-63rzzos3	26	3	can	can	MD
cord-003614-63rzzos3	26	4	be	be	VB
cord-003614-63rzzos3	26	5	The	the	DT
cord-003614-63rzzos3	26	6	original	original	JJ
cord-003614-63rzzos3	26	7	microarray	microarray	NN
cord-003614-63rzzos3	26	8	analysis	analysis	NN
cord-003614-63rzzos3	26	9	performed	perform	VBN
cord-003614-63rzzos3	26	10	by	by	IN
cord-003614-63rzzos3	26	11	Ulrich	Ulrich	NNP
cord-003614-63rzzos3	26	12	et	et	NNP
cord-003614-63rzzos3	26	13	al	al	NNP
cord-003614-63rzzos3	26	14	.	.	.
cord-003614-63rzzos3	27	1	(	(	-LRB-
cord-003614-63rzzos3	27	2	2014	2014	CD
cord-003614-63rzzos3	27	3	)	)	-RRB-
cord-003614-63rzzos3	27	4	revealed	reveal	VBD
cord-003614-63rzzos3	27	5	780	780	CD
cord-003614-63rzzos3	27	6	differentially	differentially	RB
cord-003614-63rzzos3	27	7	expressed	express	VBN
cord-003614-63rzzos3	27	8	probe	probe	NN
cord-003614-63rzzos3	27	9	sets	set	NNS
cord-003614-63rzzos3	27	10	and	and	CC
cord-003614-63rzzos3	27	11	the	the	DT
cord-003614-63rzzos3	27	12	dominating	dominate	VBG
cord-003614-63rzzos3	27	13	change	change	NN
cord-003614-63rzzos3	27	14	was	be	VBD
cord-003614-63rzzos3	27	15	an	an	DT
cord-003614-63rzzos3	27	16	up	up	JJ
cord-003614-63rzzos3	27	17	-	-	HYPH
cord-003614-63rzzos3	27	18	regulation	regulation	NN
cord-003614-63rzzos3	27	19	of	of	IN
cord-003614-63rzzos3	27	20	genes	gene	NNS
cord-003614-63rzzos3	27	21	related	relate	VBN
cord-003614-63rzzos3	27	22	to	to	IN
cord-003614-63rzzos3	27	23	the	the	DT
cord-003614-63rzzos3	27	24	innate	innate	NN
cord-003614-63rzzos3	27	25	and	and	CC
cord-003614-63rzzos3	27	26	the	the	DT
cord-003614-63rzzos3	27	27	humoral	humoral	JJ
cord-003614-63rzzos3	27	28	immune	immune	JJ
cord-003614-63rzzos3	27	29	response	response	NN
cord-003614-63rzzos3	27	30	[	[	-LRB-
cord-003614-63rzzos3	27	31	47	47	CD
cord-003614-63rzzos3	27	32	]	]	-RRB-
cord-003614-63rzzos3	27	33	.	.	.
cord-003614-63rzzos3	28	1	Of	of	IN
cord-003614-63rzzos3	28	2	110	110	CD
cord-003614-63rzzos3	28	3	manually	manually	RB
cord-003614-63rzzos3	28	4	selected	select	VBN
cord-003614-63rzzos3	28	5	genes	gene	NNS
cord-003614-63rzzos3	28	6	of	of	IN
cord-003614-63rzzos3	28	7	the	the	DT
cord-003614-63rzzos3	28	8	IFN	IFN	NNP
cord-003614-63rzzos3	28	9	-	-	HYPH
cord-003614-63rzzos3	28	10	I	I	NNP
cord-003614-63rzzos3	28	11	pathway	pathway	NN
cord-003614-63rzzos3	28	12	,	,	,
cord-003614-63rzzos3	28	13	57	57	CD
cord-003614-63rzzos3	28	14	%	%	NN
cord-003614-63rzzos3	28	15	(	(	-LRB-
cord-003614-63rzzos3	28	16	63/110	63/110	CD
cord-003614-63rzzos3	28	17	)	)	-RRB-
cord-003614-63rzzos3	28	18	were	be	VBD
cord-003614-63rzzos3	28	19	up	up	RB
cord-003614-63rzzos3	28	20	-	-	HYPH
cord-003614-63rzzos3	28	21	regulated	regulate	VBN
cord-003614-63rzzos3	28	22	in	in	IN
cord-003614-63rzzos3	28	23	a	a	DT
cord-003614-63rzzos3	28	24	relevant	relevant	JJ
cord-003614-63rzzos3	28	25	manner	manner	NN
cord-003614-63rzzos3	28	26	(	(	-LRB-
cord-003614-63rzzos3	28	27	significant	significant	JJ
cord-003614-63rzzos3	28	28	fold	fold	JJ
cord-003614-63rzzos3	28	29	change	change	NN
cord-003614-63rzzos3	28	30	>	>	XX
cord-003614-63rzzos3	28	31	1.5	1.5	CD
cord-003614-63rzzos3	28	32	)	)	-RRB-
cord-003614-63rzzos3	28	33	at	at	IN
cord-003614-63rzzos3	28	34	least	least	JJS
cord-003614-63rzzos3	28	35	in	in	IN
cord-003614-63rzzos3	28	36	one	one	CD
cord-003614-63rzzos3	28	37	group	group	NN
cord-003614-63rzzos3	28	38	of	of	IN
cord-003614-63rzzos3	28	39	CDV	CDV	NNP
cord-003614-63rzzos3	28	40	-	-	HYPH
cord-003614-63rzzos3	28	41	induced	induce	VBN
cord-003614-63rzzos3	28	42	lesions	lesion	NNS
cord-003614-63rzzos3	28	43	,	,	,
cord-003614-63rzzos3	28	44	and	and	CC
cord-003614-63rzzos3	29	1	gene	gene	NN
cord-003614-63rzzos3	29	2	expression	expression	NN
cord-003614-63rzzos3	29	3	usually	usually	RB
cord-003614-63rzzos3	29	4	peaked	peak	VBD
cord-003614-63rzzos3	29	5	in	in	IN
cord-003614-63rzzos3	29	6	the	the	DT
cord-003614-63rzzos3	29	7	subacute	subacute	JJ
cord-003614-63rzzos3	29	8	stage	stage	NN
cord-003614-63rzzos3	29	9	(	(	-LRB-
cord-003614-63rzzos3	29	10	Figure	figure	NN
cord-003614-63rzzos3	29	11	1	1	CD
cord-003614-63rzzos3	29	12	,	,	,
cord-003614-63rzzos3	29	13	Table	table	NN
cord-003614-63rzzos3	29	14	1	1	CD
cord-003614-63rzzos3	29	15	,	,	,
cord-003614-63rzzos3	29	16	 	 	_SP
cord-003614-63rzzos3	29	17	Table	Table	NNP
cord-003614-63rzzos3	29	18	S1	S1	NNP
cord-003614-63rzzos3	29	19	)	)	-RRB-
cord-003614-63rzzos3	29	20	.	.	.
cord-003614-63rzzos3	30	1	Toll	toll	NN
cord-003614-63rzzos3	30	2	-	-	HYPH
cord-003614-63rzzos3	30	3	like	like	JJ
cord-003614-63rzzos3	30	4	receptor	receptor	NN
cord-003614-63rzzos3	30	5	(	(	-LRB-
cord-003614-63rzzos3	30	6	Tlr	tlr	NN
cord-003614-63rzzos3	30	7	)	)	-RRB-
cord-003614-63rzzos3	30	8	2	2	CD
cord-003614-63rzzos3	30	9	,	,	,
cord-003614-63rzzos3	31	1	Tlr3	Tlr3	NNP
cord-003614-63rzzos3	31	2	and	and	CC
cord-003614-63rzzos3	31	3	Tlr7	Tlr7	NNP
cord-003614-63rzzos3	31	4	(	(	-LRB-
cord-003614-63rzzos3	31	5	fold	fold	VB
cord-003614-63rzzos3	31	6	change	change	NN
cord-003614-63rzzos3	31	7	up	up	IN
cord-003614-63rzzos3	31	8	to	to	IN
cord-003614-63rzzos3	31	9	4.52	4.52	CD
cord-003614-63rzzos3	31	10	,	,	,
cord-003614-63rzzos3	31	11	8.00	8.00	CD
cord-003614-63rzzos3	31	12	and	and	CC
cord-003614-63rzzos3	31	13	2.83	2.83	CD
cord-003614-63rzzos3	31	14	)	)	-RRB-
cord-003614-63rzzos3	31	15	were	be	VBD
cord-003614-63rzzos3	31	16	moderately	moderately	RB
cord-003614-63rzzos3	31	17	increased	increase	VBN
cord-003614-63rzzos3	31	18	,	,	,
cord-003614-63rzzos3	31	19	whereas	whereas	IN
cord-003614-63rzzos3	31	20	Pkr	Pkr	NNP
cord-003614-63rzzos3	31	21	and	and	CC
cord-003614-63rzzos3	31	22	Mda5	Mda5	NNP
cord-003614-63rzzos3	31	23	were	be	VBD
cord-003614-63rzzos3	31	24	highly	highly	RB
cord-003614-63rzzos3	31	25	up	up	RB
cord-003614-63rzzos3	31	26	-	-	HYPH
cord-003614-63rzzos3	31	27	regulated	regulated	JJ
cord-003614-63rzzos3	31	28	(	(	-LRB-
cord-003614-63rzzos3	31	29	fold	fold	VB
cord-003614-63rzzos3	31	30	change	change	NN
cord-003614-63rzzos3	31	31	up	up	IN
cord-003614-63rzzos3	31	32	to	to	IN
cord-003614-63rzzos3	31	33	15.62	15.62	CD
cord-003614-63rzzos3	31	34	and	and	CC
cord-003614-63rzzos3	31	35	33.76	33.76	CD
cord-003614-63rzzos3	31	36	)	)	-RRB-
cord-003614-63rzzos3	31	37	.	.	.
cord-003614-63rzzos3	32	1	Only	only	RB
cord-003614-63rzzos3	32	2	a	a	DT
cord-003614-63rzzos3	32	3	mild	mild	JJ
cord-003614-63rzzos3	32	4	increase	increase	NN
cord-003614-63rzzos3	32	5	in	in	IN
cord-003614-63rzzos3	32	6	Irf3	Irf3	NNP
cord-003614-63rzzos3	32	7	,	,	,
cord-003614-63rzzos3	32	8	Irf5	Irf5	NNP
cord-003614-63rzzos3	32	9	and	and	CC
cord-003614-63rzzos3	32	10	nuclear	nuclear	JJ
cord-003614-63rzzos3	32	11	factor	factor	NN
cord-003614-63rzzos3	32	12	of	of	IN
cord-003614-63rzzos3	32	13	kappa	kappa	NNP
cord-003614-63rzzos3	32	14	light	light	NNP
cord-003614-63rzzos3	32	15	polypeptide	polypeptide	NN
cord-003614-63rzzos3	32	16	gene	gene	NN
cord-003614-63rzzos3	32	17	enhancer	enhancer	NN
cord-003614-63rzzos3	32	18	in	in	IN
cord-003614-63rzzos3	32	19	B	b	NN
cord-003614-63rzzos3	32	20	-	-	HYPH
cord-003614-63rzzos3	32	21	cells	cell	NNS
cord-003614-63rzzos3	32	22	(	(	-LRB-
cord-003614-63rzzos3	32	23	Nfkb	Nfkb	NNP
cord-003614-63rzzos3	32	24	)	)	-RRB-
cord-003614-63rzzos3	32	25	1	1	CD
cord-003614-63rzzos3	32	26	gene	gene	NN
cord-003614-63rzzos3	32	27	expression	expression	NN
cord-003614-63rzzos3	32	28	(	(	-LRB-
cord-003614-63rzzos3	32	29	fold	fold	VB
cord-003614-63rzzos3	32	30	change	change	NN
cord-003614-63rzzos3	32	31	<	<	XX
cord-003614-63rzzos3	32	32	2	2	CD
cord-003614-63rzzos3	32	33	)	)	-RRB-
cord-003614-63rzzos3	32	34	was	be	VBD
cord-003614-63rzzos3	32	35	found	find	VBN
cord-003614-63rzzos3	32	36	,	,	,
cord-003614-63rzzos3	32	37	whereas	whereas	IN
cord-003614-63rzzos3	32	38	Irf1	Irf1	NNP
cord-003614-63rzzos3	32	39	and	and	CC
cord-003614-63rzzos3	32	40	Irf7	Irf7	NNP
cord-003614-63rzzos3	32	41	were	be	VBD
cord-003614-63rzzos3	32	42	strongly	strongly	RB
cord-003614-63rzzos3	32	43	induced	induce	VBN
cord-003614-63rzzos3	32	44	(	(	-LRB-
cord-003614-63rzzos3	32	45	fold	fold	VB
cord-003614-63rzzos3	32	46	change	change	NN
cord-003614-63rzzos3	32	47	up	up	IN
cord-003614-63rzzos3	32	48	to	to	IN
cord-003614-63rzzos3	32	49	30.13	30.13	CD
cord-003614-63rzzos3	32	50	and	and	CC
cord-003614-63rzzos3	32	51	113.54	113.54	CD
cord-003614-63rzzos3	32	52	)	)	-RRB-
cord-003614-63rzzos3	32	53	.	.	.
cord-003614-63rzzos3	33	1	No	no	DT
cord-003614-63rzzos3	33	2	transcriptional	transcriptional	JJ
cord-003614-63rzzos3	33	3	changes	change	NNS
cord-003614-63rzzos3	33	4	were	be	VBD
cord-003614-63rzzos3	33	5	found	find	VBN
cord-003614-63rzzos3	33	6	in	in	IN
cord-003614-63rzzos3	33	7	IFN	IFN	NNP
cord-003614-63rzzos3	33	8	-	-	HYPH
cord-003614-63rzzos3	33	9	I	i	NN
cord-003614-63rzzos3	33	10	gene	gene	NN
cord-003614-63rzzos3	33	11	expression	expression	NN
cord-003614-63rzzos3	33	12	and	and	CC
cord-003614-63rzzos3	33	13	Ifnar	Ifnar	NNP
cord-003614-63rzzos3	33	14	genes	gene	NNS
cord-003614-63rzzos3	33	15	were	be	VBD
cord-003614-63rzzos3	33	16	only	only	RB
cord-003614-63rzzos3	33	17	mildly	mildly	RB
cord-003614-63rzzos3	33	18	increased	increase	VBN
cord-003614-63rzzos3	33	19	(	(	-LRB-
cord-003614-63rzzos3	33	20	fold	fold	VB
cord-003614-63rzzos3	33	21	change	change	NN
cord-003614-63rzzos3	33	22	<	<	XX
cord-003614-63rzzos3	33	23	2	2	CD
cord-003614-63rzzos3	33	24	)	)	-RRB-
cord-003614-63rzzos3	33	25	in	in	IN
cord-003614-63rzzos3	33	26	the	the	DT
cord-003614-63rzzos3	33	27	subacute	subacute	JJ
cord-003614-63rzzos3	33	28	stage	stage	NN
cord-003614-63rzzos3	33	29	of	of	IN
cord-003614-63rzzos3	33	30	CDV	CDV	NNP
cord-003614-63rzzos3	33	31	-	-	HYPH
cord-003614-63rzzos3	33	32	infection	infection	NN
cord-003614-63rzzos3	33	33	.	.	.
cord-003614-63rzzos3	34	1	Similarly	similarly	RB
cord-003614-63rzzos3	34	2	,	,	,
cord-003614-63rzzos3	34	3	most	most	JJS
cord-003614-63rzzos3	34	4	signal	signal	NN
cord-003614-63rzzos3	34	5	transducers	transducer	NNS
cord-003614-63rzzos3	34	6	including	include	VBG
cord-003614-63rzzos3	34	7	Jak1	Jak1	NNP
cord-003614-63rzzos3	34	8	,	,	,
cord-003614-63rzzos3	34	9	Socs1	socs1	JJ
cord-003614-63rzzos3	34	10	and	and	CC
cord-003614-63rzzos3	34	11	Tyk2	Tyk2	NNP
cord-003614-63rzzos3	34	12	did	do	VBD
cord-003614-63rzzos3	34	13	not	not	RB
cord-003614-63rzzos3	34	14	show	show	VB
cord-003614-63rzzos3	34	15	significant	significant	JJ
cord-003614-63rzzos3	34	16	transcriptional	transcriptional	JJ
cord-003614-63rzzos3	34	17	changes	change	NNS
cord-003614-63rzzos3	34	18	.	.	.
cord-003614-63rzzos3	35	1	Nevertheless	nevertheless	RB
cord-003614-63rzzos3	35	2	,	,	,
cord-003614-63rzzos3	35	3	Stat1	Stat1	NNS
cord-003614-63rzzos3	35	4	,	,	,
cord-003614-63rzzos3	36	1	Stat2	stat2	NN
cord-003614-63rzzos3	37	1	and	and	CC
cord-003614-63rzzos3	37	2	Irf9	Irf9	NNP
cord-003614-63rzzos3	37	3	were	be	VBD
cord-003614-63rzzos3	37	4	moderately	moderately	RB
cord-003614-63rzzos3	37	5	up	up	RB
cord-003614-63rzzos3	37	6	-	-	HYPH
cord-003614-63rzzos3	37	7	regulated	regulated	JJ
cord-003614-63rzzos3	37	8	(	(	-LRB-
cord-003614-63rzzos3	37	9	fold	fold	VB
cord-003614-63rzzos3	37	10	change	change	NN
cord-003614-63rzzos3	37	11	up	up	IN
cord-003614-63rzzos3	37	12	to	to	IN
cord-003614-63rzzos3	37	13	19.19	19.19	CD
cord-003614-63rzzos3	37	14	,	,	,
cord-003614-63rzzos3	37	15	4.57	4.57	CD
cord-003614-63rzzos3	37	16	and	and	CC
cord-003614-63rzzos3	37	17	11.44	11.44	CD
cord-003614-63rzzos3	37	18	)	)	-RRB-
cord-003614-63rzzos3	37	19	.	.	.
cord-003614-63rzzos3	38	1	The	the	DT
cord-003614-63rzzos3	38	2	classical	classical	JJ
cord-003614-63rzzos3	38	3	ISGs	isg	NNS
cord-003614-63rzzos3	38	4	were	be	VBD
cord-003614-63rzzos3	38	5	strongly	strongly	RB
cord-003614-63rzzos3	38	6	induced	induce	VBN
cord-003614-63rzzos3	38	7	by	by	IN
cord-003614-63rzzos3	38	8	CDV	CDV	NNP
cord-003614-63rzzos3	38	9	-	-	HYPH
cord-003614-63rzzos3	38	10	infection	infection	NN
cord-003614-63rzzos3	38	11	with	with	IN
cord-003614-63rzzos3	38	12	particularly	particularly	RB
cord-003614-63rzzos3	38	13	high	high	JJ
cord-003614-63rzzos3	38	14	levels	level	NNS
cord-003614-63rzzos3	38	15	for	for	IN
cord-003614-63rzzos3	38	16	Isg15	Isg15	NNP
cord-003614-63rzzos3	38	17	,	,	,
cord-003614-63rzzos3	38	18	Ifi44l	Ifi44l	NNP
cord-003614-63rzzos3	38	19	,	,	,
cord-003614-63rzzos3	38	20	Isg56	Isg56	NNP
cord-003614-63rzzos3	38	21	,	,	,
cord-003614-63rzzos3	38	22	Oas2	Oas2	NNP
cord-003614-63rzzos3	38	23	and	and	CC
cord-003614-63rzzos3	38	24	Mx2	Mx2	NNP
cord-003614-63rzzos3	38	25	(	(	-LRB-
cord-003614-63rzzos3	38	26	fold	fold	VB
cord-003614-63rzzos3	38	27	change	change	NN
cord-003614-63rzzos3	38	28	up	up	IN
cord-003614-63rzzos3	38	29	to	to	IN
cord-003614-63rzzos3	38	30	928	928	CD
cord-003614-63rzzos3	38	31	.	.	.
cord-003614-63rzzos3	39	1	35	35	CD
cord-003614-63rzzos3	39	2	,	,	,
cord-003614-63rzzos3	39	3	419.93	419.93	CD
cord-003614-63rzzos3	39	4	,	,	,
cord-003614-63rzzos3	39	5	179	179	CD
cord-003614-63rzzos3	39	6	.05	.05	CD
cord-003614-63rzzos3	39	7	,	,	,
cord-003614-63rzzos3	39	8	173.57	173.57	CD
cord-003614-63rzzos3	39	9	and	and	CC
cord-003614-63rzzos3	39	10	147.59	147.59	CD
cord-003614-63rzzos3	39	11	)	)	-RRB-
cord-003614-63rzzos3	39	12	.	.	.
cord-003614-63rzzos3	40	1	Additionally	additionally	RB
cord-003614-63rzzos3	40	2	,	,	,
cord-003614-63rzzos3	40	3	several	several	JJ
cord-003614-63rzzos3	40	4	MHC	MHC	NNP
cord-003614-63rzzos3	40	5	class	class	NN
cord-003614-63rzzos3	40	6	I	i	NN
cord-003614-63rzzos3	40	7	and	and	CC
cord-003614-63rzzos3	40	8	class	class	NN
cord-003614-63rzzos3	40	9	II	ii	CD
cord-003614-63rzzos3	40	10	genes	gene	NNS
cord-003614-63rzzos3	40	11	were	be	VBD
cord-003614-63rzzos3	40	12	highly	highly	RB
cord-003614-63rzzos3	40	13	up	up	RB
cord-003614-63rzzos3	40	14	-	-	HYPH
cord-003614-63rzzos3	40	15	regulated	regulated	JJ
cord-003614-63rzzos3	40	16	(	(	-LRB-
cord-003614-63rzzos3	40	17	fold	fold	VB
cord-003614-63rzzos3	40	18	change	change	NN
cord-003614-63rzzos3	40	19	up	up	IN
cord-003614-63rzzos3	40	20	to	to	IN
cord-003614-63rzzos3	40	21	135	135	CD
cord-003614-63rzzos3	40	22	.	.	.
cord-003614-63rzzos3	41	1	55	55	CD
cord-003614-63rzzos3	41	2	and	and	CC
cord-003614-63rzzos3	41	3	30.97	30.97	CD
cord-003614-63rzzos3	41	4	)	)	-RRB-
cord-003614-63rzzos3	41	5	.	.	.
cord-003614-63rzzos3	42	1	An	an	DT
cord-003614-63rzzos3	42	2	overview	overview	NN
cord-003614-63rzzos3	42	3	of	of	IN
cord-003614-63rzzos3	42	4	fold	fold	JJ
cord-003614-63rzzos3	42	5	changes	change	NNS
cord-003614-63rzzos3	42	6	for	for	IN
cord-003614-63rzzos3	42	7	selected	select	VBN
cord-003614-63rzzos3	42	8	interferon	interferon	NN
cord-003614-63rzzos3	42	9	-	-	HYPH
cord-003614-63rzzos3	42	10	dependent	dependent	JJ
cord-003614-63rzzos3	42	11	genes	gene	NNS
cord-003614-63rzzos3	42	12	is	be	VBZ
cord-003614-63rzzos3	42	13	given	give	VBN
cord-003614-63rzzos3	42	14	in	in	IN
cord-003614-63rzzos3	42	15	Figure	figure	NN
cord-003614-63rzzos3	42	16	1	1	CD
cord-003614-63rzzos3	42	17	,	,	,
cord-003614-63rzzos3	42	18	Table	table	NN
cord-003614-63rzzos3	42	19	1	1	CD
cord-003614-63rzzos3	42	20	and	and	CC
cord-003614-63rzzos3	42	21	Table	Table	NNP
cord-003614-63rzzos3	42	22	S1	S1	NNP
cord-003614-63rzzos3	42	23	.	.	.
cord-003614-63rzzos3	42	24	 	 	_SP
cord-003614-63rzzos3	43	1	The	the	DT
cord-003614-63rzzos3	43	2	original	original	JJ
cord-003614-63rzzos3	43	3	microarray	microarray	NN
cord-003614-63rzzos3	43	4	analysis	analysis	NN
cord-003614-63rzzos3	43	5	performed	perform	VBN
cord-003614-63rzzos3	43	6	by	by	IN
cord-003614-63rzzos3	43	7	Ulrich	Ulrich	NNP
cord-003614-63rzzos3	43	8	et	et	NNP
cord-003614-63rzzos3	43	9	al	al	NNP
cord-003614-63rzzos3	43	10	.	.	.
cord-003614-63rzzos3	44	1	(	(	-LRB-
cord-003614-63rzzos3	44	2	2014	2014	CD
cord-003614-63rzzos3	44	3	)	)	-RRB-
cord-003614-63rzzos3	44	4	revealed	reveal	VBD
cord-003614-63rzzos3	44	5	780	780	CD
cord-003614-63rzzos3	44	6	differentially	differentially	RB
cord-003614-63rzzos3	44	7	expressed	express	VBN
cord-003614-63rzzos3	44	8	probe	probe	NN
cord-003614-63rzzos3	44	9	sets	set	NNS
cord-003614-63rzzos3	44	10	and	and	CC
cord-003614-63rzzos3	44	11	the	the	DT
cord-003614-63rzzos3	44	12	dominating	dominate	VBG
cord-003614-63rzzos3	44	13	change	change	NN
cord-003614-63rzzos3	44	14	was	be	VBD
cord-003614-63rzzos3	44	15	an	an	DT
cord-003614-63rzzos3	44	16	up	up	JJ
cord-003614-63rzzos3	44	17	-	-	HYPH
cord-003614-63rzzos3	44	18	regulation	regulation	NN
cord-003614-63rzzos3	44	19	of	of	IN
cord-003614-63rzzos3	44	20	genes	gene	NNS
cord-003614-63rzzos3	44	21	related	relate	VBN
cord-003614-63rzzos3	44	22	to	to	IN
cord-003614-63rzzos3	44	23	the	the	DT
cord-003614-63rzzos3	44	24	innate	innate	NN
cord-003614-63rzzos3	44	25	and	and	CC
cord-003614-63rzzos3	44	26	the	the	DT
cord-003614-63rzzos3	44	27	humoral	humoral	JJ
cord-003614-63rzzos3	44	28	immune	immune	JJ
cord-003614-63rzzos3	44	29	response	response	NN
cord-003614-63rzzos3	44	30	[	[	-LRB-
cord-003614-63rzzos3	44	31	47	47	CD
cord-003614-63rzzos3	44	32	]	]	-RRB-
cord-003614-63rzzos3	44	33	.	.	.
cord-003614-63rzzos3	45	1	Of	of	IN
cord-003614-63rzzos3	45	2	110	110	CD
cord-003614-63rzzos3	45	3	manually	manually	RB
cord-003614-63rzzos3	45	4	selected	select	VBN
cord-003614-63rzzos3	45	5	genes	gene	NNS
cord-003614-63rzzos3	45	6	of	of	IN
cord-003614-63rzzos3	45	7	the	the	DT
cord-003614-63rzzos3	45	8	IFN	IFN	NNP
cord-003614-63rzzos3	45	9	-	-	HYPH
cord-003614-63rzzos3	45	10	I	I	NNP
cord-003614-63rzzos3	45	11	pathway	pathway	NN
cord-003614-63rzzos3	45	12	,	,	,
cord-003614-63rzzos3	45	13	57	57	CD
cord-003614-63rzzos3	45	14	%	%	NN
cord-003614-63rzzos3	45	15	(	(	-LRB-
cord-003614-63rzzos3	45	16	63/110	63/110	CD
cord-003614-63rzzos3	45	17	)	)	-RRB-
cord-003614-63rzzos3	45	18	were	be	VBD
cord-003614-63rzzos3	45	19	up	up	RB
cord-003614-63rzzos3	45	20	-	-	HYPH
cord-003614-63rzzos3	45	21	regulated	regulate	VBN
cord-003614-63rzzos3	45	22	in	in	IN
cord-003614-63rzzos3	45	23	a	a	DT
cord-003614-63rzzos3	45	24	relevant	relevant	JJ
cord-003614-63rzzos3	45	25	manner	manner	NN
cord-003614-63rzzos3	45	26	(	(	-LRB-
cord-003614-63rzzos3	45	27	significant	significant	JJ
cord-003614-63rzzos3	45	28	fold	fold	JJ
cord-003614-63rzzos3	45	29	change	change	NN
cord-003614-63rzzos3	45	30	>	>	XX
cord-003614-63rzzos3	45	31	1.5	1.5	CD
cord-003614-63rzzos3	45	32	)	)	-RRB-
cord-003614-63rzzos3	45	33	at	at	IN
cord-003614-63rzzos3	45	34	least	least	JJS
cord-003614-63rzzos3	45	35	in	in	IN
cord-003614-63rzzos3	45	36	one	one	CD
cord-003614-63rzzos3	45	37	group	group	NN
cord-003614-63rzzos3	45	38	of	of	IN
cord-003614-63rzzos3	45	39	CDV	CDV	NNP
cord-003614-63rzzos3	45	40	-	-	HYPH
cord-003614-63rzzos3	45	41	induced	induce	VBN
cord-003614-63rzzos3	45	42	lesions	lesion	NNS
cord-003614-63rzzos3	45	43	,	,	,
cord-003614-63rzzos3	45	44	and	and	CC
cord-003614-63rzzos3	46	1	gene	gene	NN
cord-003614-63rzzos3	46	2	expression	expression	NN
cord-003614-63rzzos3	46	3	usually	usually	RB
cord-003614-63rzzos3	46	4	peaked	peak	VBD
cord-003614-63rzzos3	46	5	in	in	IN
cord-003614-63rzzos3	46	6	the	the	DT
cord-003614-63rzzos3	46	7	subacute	subacute	JJ
cord-003614-63rzzos3	46	8	stage	stage	NN
cord-003614-63rzzos3	46	9	(	(	-LRB-
cord-003614-63rzzos3	46	10	Figure	figure	NN
cord-003614-63rzzos3	46	11	1	1	CD
cord-003614-63rzzos3	46	12	,	,	,
cord-003614-63rzzos3	46	13	Table	table	NN
cord-003614-63rzzos3	46	14	1	1	CD
cord-003614-63rzzos3	46	15	,	,	,
cord-003614-63rzzos3	46	16	Table	Table	NNP
cord-003614-63rzzos3	46	17	S1	S1	NNP
cord-003614-63rzzos3	46	18	)	)	-RRB-
cord-003614-63rzzos3	46	19	.	.	.
cord-003614-63rzzos3	47	1	Toll	toll	NN
cord-003614-63rzzos3	47	2	-	-	HYPH
cord-003614-63rzzos3	47	3	like	like	JJ
cord-003614-63rzzos3	47	4	receptor	receptor	NN
cord-003614-63rzzos3	47	5	(	(	-LRB-
cord-003614-63rzzos3	47	6	Tlr	tlr	NN
cord-003614-63rzzos3	47	7	)	)	-RRB-
cord-003614-63rzzos3	47	8	2	2	CD
cord-003614-63rzzos3	47	9	,	,	,
cord-003614-63rzzos3	48	1	Tlr3	Tlr3	NNP
cord-003614-63rzzos3	48	2	and	and	CC
cord-003614-63rzzos3	48	3	Tlr7	Tlr7	NNP
cord-003614-63rzzos3	48	4	(	(	-LRB-
cord-003614-63rzzos3	48	5	fold	fold	VB
cord-003614-63rzzos3	48	6	change	change	NN
cord-003614-63rzzos3	48	7	up	up	IN
cord-003614-63rzzos3	48	8	to	to	IN
cord-003614-63rzzos3	48	9	4.52	4.52	CD
cord-003614-63rzzos3	48	10	,	,	,
cord-003614-63rzzos3	48	11	8.00	8.00	CD
cord-003614-63rzzos3	48	12	and	and	CC
cord-003614-63rzzos3	48	13	2.83	2.83	CD
cord-003614-63rzzos3	48	14	)	)	-RRB-
cord-003614-63rzzos3	48	15	were	be	VBD
cord-003614-63rzzos3	48	16	moderately	moderately	RB
cord-003614-63rzzos3	48	17	increased	increase	VBN
cord-003614-63rzzos3	48	18	,	,	,
cord-003614-63rzzos3	48	19	whereas	whereas	IN
cord-003614-63rzzos3	48	20	Pkr	Pkr	NNP
cord-003614-63rzzos3	48	21	and	and	CC
cord-003614-63rzzos3	48	22	Mda5	Mda5	NNP
cord-003614-63rzzos3	48	23	were	be	VBD
cord-003614-63rzzos3	48	24	highly	highly	RB
cord-003614-63rzzos3	48	25	up	up	RB
cord-003614-63rzzos3	48	26	-	-	HYPH
cord-003614-63rzzos3	48	27	regulated	regulated	JJ
cord-003614-63rzzos3	48	28	(	(	-LRB-
cord-003614-63rzzos3	48	29	fold	fold	VB
cord-003614-63rzzos3	48	30	change	change	NN
cord-003614-63rzzos3	48	31	up	up	IN
cord-003614-63rzzos3	48	32	to	to	IN
cord-003614-63rzzos3	48	33	15.62	15.62	CD
cord-003614-63rzzos3	48	34	and	and	CC
cord-003614-63rzzos3	48	35	33.76	33.76	CD
cord-003614-63rzzos3	48	36	)	)	-RRB-
cord-003614-63rzzos3	48	37	.	.	.
cord-003614-63rzzos3	49	1	Only	only	RB
cord-003614-63rzzos3	49	2	a	a	DT
cord-003614-63rzzos3	49	3	mild	mild	JJ
cord-003614-63rzzos3	49	4	increase	increase	NN
cord-003614-63rzzos3	49	5	in	in	IN
cord-003614-63rzzos3	49	6	Irf3	Irf3	NNP
cord-003614-63rzzos3	49	7	,	,	,
cord-003614-63rzzos3	49	8	Irf5	Irf5	NNP
cord-003614-63rzzos3	49	9	and	and	CC
cord-003614-63rzzos3	49	10	nuclear	nuclear	JJ
cord-003614-63rzzos3	49	11	factor	factor	NN
cord-003614-63rzzos3	49	12	of	of	IN
cord-003614-63rzzos3	49	13	kappa	kappa	NNP
cord-003614-63rzzos3	49	14	light	light	NNP
cord-003614-63rzzos3	49	15	polypeptide	polypeptide	NN
cord-003614-63rzzos3	49	16	gene	gene	NN
cord-003614-63rzzos3	49	17	enhancer	enhancer	NN
cord-003614-63rzzos3	49	18	in	in	IN
cord-003614-63rzzos3	49	19	B	b	NN
cord-003614-63rzzos3	49	20	-	-	HYPH
cord-003614-63rzzos3	49	21	cells	cell	NNS
cord-003614-63rzzos3	49	22	(	(	-LRB-
cord-003614-63rzzos3	49	23	Nfkb	Nfkb	NNP
cord-003614-63rzzos3	49	24	)	)	-RRB-
cord-003614-63rzzos3	49	25	1	1	CD
cord-003614-63rzzos3	49	26	gene	gene	NN
cord-003614-63rzzos3	49	27	expression	expression	NN
cord-003614-63rzzos3	49	28	(	(	-LRB-
cord-003614-63rzzos3	49	29	fold	fold	VB
cord-003614-63rzzos3	49	30	change	change	NN
cord-003614-63rzzos3	49	31	<	<	XX
cord-003614-63rzzos3	49	32	2	2	CD
cord-003614-63rzzos3	49	33	)	)	-RRB-
cord-003614-63rzzos3	49	34	was	be	VBD
cord-003614-63rzzos3	49	35	found	find	VBN
cord-003614-63rzzos3	49	36	,	,	,
cord-003614-63rzzos3	49	37	whereas	whereas	IN
cord-003614-63rzzos3	49	38	Irf1	Irf1	NNP
cord-003614-63rzzos3	49	39	and	and	CC
cord-003614-63rzzos3	49	40	Irf7	Irf7	NNP
cord-003614-63rzzos3	49	41	were	be	VBD
cord-003614-63rzzos3	49	42	strongly	strongly	RB
cord-003614-63rzzos3	49	43	induced	induce	VBN
cord-003614-63rzzos3	49	44	(	(	-LRB-
cord-003614-63rzzos3	49	45	fold	fold	VB
cord-003614-63rzzos3	49	46	change	change	NN
cord-003614-63rzzos3	49	47	up	up	IN
cord-003614-63rzzos3	49	48	to	to	IN
cord-003614-63rzzos3	49	49	30.13	30.13	CD
cord-003614-63rzzos3	49	50	and	and	CC
cord-003614-63rzzos3	49	51	113.54	113.54	CD
cord-003614-63rzzos3	49	52	)	)	-RRB-
cord-003614-63rzzos3	49	53	.	.	.
cord-003614-63rzzos3	50	1	No	no	DT
cord-003614-63rzzos3	50	2	transcriptional	transcriptional	JJ
cord-003614-63rzzos3	50	3	changes	change	NNS
cord-003614-63rzzos3	50	4	were	be	VBD
cord-003614-63rzzos3	50	5	found	find	VBN
cord-003614-63rzzos3	50	6	in	in	IN
cord-003614-63rzzos3	50	7	IFN	IFN	NNP
cord-003614-63rzzos3	50	8	-	-	HYPH
cord-003614-63rzzos3	50	9	I	i	NN
cord-003614-63rzzos3	50	10	gene	gene	NN
cord-003614-63rzzos3	50	11	expression	expression	NN
cord-003614-63rzzos3	50	12	and	and	CC
cord-003614-63rzzos3	50	13	Ifnar	Ifnar	NNP
cord-003614-63rzzos3	50	14	genes	gene	NNS
cord-003614-63rzzos3	50	15	were	be	VBD
cord-003614-63rzzos3	50	16	only	only	RB
cord-003614-63rzzos3	50	17	mildly	mildly	RB
cord-003614-63rzzos3	50	18	increased	increase	VBN
cord-003614-63rzzos3	50	19	(	(	-LRB-
cord-003614-63rzzos3	50	20	fold	fold	VB
cord-003614-63rzzos3	50	21	change	change	NN
cord-003614-63rzzos3	50	22	<	<	XX
cord-003614-63rzzos3	50	23	2	2	CD
cord-003614-63rzzos3	50	24	)	)	-RRB-
cord-003614-63rzzos3	50	25	in	in	IN
cord-003614-63rzzos3	50	26	the	the	DT
cord-003614-63rzzos3	50	27	subacute	subacute	JJ
cord-003614-63rzzos3	50	28	stage	stage	NN
cord-003614-63rzzos3	50	29	of	of	IN
cord-003614-63rzzos3	50	30	CDV	CDV	NNP
cord-003614-63rzzos3	50	31	-	-	HYPH
cord-003614-63rzzos3	50	32	infection	infection	NN
cord-003614-63rzzos3	50	33	.	.	.
cord-003614-63rzzos3	51	1	Similarly	similarly	RB
cord-003614-63rzzos3	51	2	,	,	,
cord-003614-63rzzos3	51	3	most	most	JJS
cord-003614-63rzzos3	51	4	signal	signal	NN
cord-003614-63rzzos3	51	5	transducers	transducer	NNS
cord-003614-63rzzos3	51	6	including	include	VBG
cord-003614-63rzzos3	51	7	Jak1	Jak1	NNP
cord-003614-63rzzos3	51	8	,	,	,
cord-003614-63rzzos3	51	9	Socs1	socs1	JJ
cord-003614-63rzzos3	51	10	and	and	CC
cord-003614-63rzzos3	51	11	Tyk2	Tyk2	NNP
cord-003614-63rzzos3	51	12	did	do	VBD
cord-003614-63rzzos3	51	13	not	not	RB
cord-003614-63rzzos3	51	14	show	show	VB
cord-003614-63rzzos3	51	15	significant	significant	JJ
cord-003614-63rzzos3	51	16	transcriptional	transcriptional	JJ
cord-003614-63rzzos3	51	17	changes	change	NNS
cord-003614-63rzzos3	51	18	.	.	.
cord-003614-63rzzos3	52	1	Nevertheless	nevertheless	RB
cord-003614-63rzzos3	52	2	,	,	,
cord-003614-63rzzos3	52	3	Stat1	Stat1	NNS
cord-003614-63rzzos3	52	4	,	,	,
cord-003614-63rzzos3	53	1	Stat2	stat2	NN
cord-003614-63rzzos3	54	1	and	and	CC
cord-003614-63rzzos3	54	2	Irf9	Irf9	NNP
cord-003614-63rzzos3	54	3	were	be	VBD
cord-003614-63rzzos3	54	4	moderately	moderately	RB
cord-003614-63rzzos3	54	5	up	up	RB
cord-003614-63rzzos3	54	6	-	-	HYPH
cord-003614-63rzzos3	54	7	regulated	regulated	JJ
cord-003614-63rzzos3	54	8	(	(	-LRB-
cord-003614-63rzzos3	54	9	fold	fold	VB
cord-003614-63rzzos3	54	10	change	change	NN
cord-003614-63rzzos3	54	11	up	up	IN
cord-003614-63rzzos3	54	12	to	to	IN
cord-003614-63rzzos3	54	13	19.19	19.19	CD
cord-003614-63rzzos3	54	14	,	,	,
cord-003614-63rzzos3	54	15	4.57	4.57	CD
cord-003614-63rzzos3	54	16	and	and	CC
cord-003614-63rzzos3	54	17	11.44	11.44	CD
cord-003614-63rzzos3	54	18	55	55	CD
cord-003614-63rzzos3	54	19	and	and	CC
cord-003614-63rzzos3	54	20	30.97	30.97	CD
cord-003614-63rzzos3	54	21	)	)	-RRB-
cord-003614-63rzzos3	54	22	.	.	.
cord-003614-63rzzos3	55	1	An	an	DT
cord-003614-63rzzos3	55	2	overview	overview	NN
cord-003614-63rzzos3	55	3	of	of	IN
cord-003614-63rzzos3	55	4	fold	fold	JJ
cord-003614-63rzzos3	55	5	changes	change	NNS
cord-003614-63rzzos3	55	6	for	for	IN
cord-003614-63rzzos3	55	7	selected	select	VBN
cord-003614-63rzzos3	55	8	interferon	interferon	NN
cord-003614-63rzzos3	55	9	-	-	HYPH
cord-003614-63rzzos3	55	10	dependent	dependent	JJ
cord-003614-63rzzos3	55	11	genes	gene	NNS
cord-003614-63rzzos3	55	12	is	be	VBZ
cord-003614-63rzzos3	55	13	given	give	VBN
cord-003614-63rzzos3	55	14	(	(	-LRB-
cord-003614-63rzzos3	55	15	NFκB	NFκB	NNP
cord-003614-63rzzos3	55	16	,	,	,
cord-003614-63rzzos3	55	17	IRF1	IRF1	NNP
cord-003614-63rzzos3	55	18	,	,	,
cord-003614-63rzzos3	55	19	IRF3	IRF3	NNP
cord-003614-63rzzos3	55	20	,	,	,
cord-003614-63rzzos3	55	21	IRF5	IRF5	NNP
cord-003614-63rzzos3	55	22	,	,	,
cord-003614-63rzzos3	55	23	IRF7	IRF7	NNP
cord-003614-63rzzos3	55	24	)	)	-RRB-
cord-003614-63rzzos3	55	25	.	.	.
cord-003614-63rzzos3	56	1	These	these	DT
cord-003614-63rzzos3	56	2	transcription	transcription	NN
cord-003614-63rzzos3	56	3	factors	factor	NNS
cord-003614-63rzzos3	56	4	translocate	translocate	VBP
cord-003614-63rzzos3	56	5	into	into	IN
cord-003614-63rzzos3	56	6	the	the	DT
cord-003614-63rzzos3	56	7	nucleus	nucleus	NN
cord-003614-63rzzos3	56	8	and	and	CC
cord-003614-63rzzos3	56	9	induce	induce	VB
cord-003614-63rzzos3	56	10	IFN	IFN	NNP
cord-003614-63rzzos3	56	11	-	-	HYPH
cord-003614-63rzzos3	56	12	I	-PRON-	PRP
cord-003614-63rzzos3	56	13	expression	expression	NN
cord-003614-63rzzos3	56	14	.	.	.
cord-003614-63rzzos3	57	1	Right	right	JJ
cord-003614-63rzzos3	57	2	side	side	NN
cord-003614-63rzzos3	57	3	:	:	:
cord-003614-63rzzos3	57	4	Receptor	receptor	NN
cord-003614-63rzzos3	57	5	binding	binding	NN
cord-003614-63rzzos3	57	6	of	of	IN
cord-003614-63rzzos3	57	7	IFN	IFN	NNP
cord-003614-63rzzos3	58	1	-I	-I	NNP
cord-003614-63rzzos3	58	2	activates	activate	VBZ
cord-003614-63rzzos3	58	3	the	the	DT
cord-003614-63rzzos3	58	4	JAK	JAK	NNP
cord-003614-63rzzos3	58	5	-	-	HYPH
cord-003614-63rzzos3	58	6	STAT	STAT	NNP
cord-003614-63rzzos3	58	7	signaling	signal	VBG
cord-003614-63rzzos3	58	8	pathway	pathway	NN
cord-003614-63rzzos3	58	9	leading	lead	VBG
cord-003614-63rzzos3	58	10	to	to	IN
cord-003614-63rzzos3	58	11	the	the	DT
cord-003614-63rzzos3	58	12	formation	formation	NN
cord-003614-63rzzos3	58	13	of	of	IN
cord-003614-63rzzos3	58	14	STAT1	stat1	NN
cord-003614-63rzzos3	58	15	/	/	SYM
cord-003614-63rzzos3	58	16	STAT2	STAT2	NNS
cord-003614-63rzzos3	58	17	heterodimers	heterodimer	NNS
cord-003614-63rzzos3	58	18	in	in	IN
cord-003614-63rzzos3	58	19	the	the	DT
cord-003614-63rzzos3	58	20	cytoplasm	cytoplasm	NN
cord-003614-63rzzos3	58	21	.	.	.
cord-003614-63rzzos3	59	1	These	these	DT
cord-003614-63rzzos3	59	2	heterodimers	heterodimer	NNS
cord-003614-63rzzos3	59	3	form	form	VBP
cord-003614-63rzzos3	59	4	a	a	DT
cord-003614-63rzzos3	59	5	complex	complex	NN
cord-003614-63rzzos3	59	6	with	with	IN
cord-003614-63rzzos3	59	7	IRF9	IRF9	NNP
cord-003614-63rzzos3	59	8	,	,	,
cord-003614-63rzzos3	59	9	termed	term	VBN
cord-003614-63rzzos3	59	10	interferon	interferon	NN
cord-003614-63rzzos3	59	11	-	-	HYPH
cord-003614-63rzzos3	59	12	stimulated	stimulate	VBN
cord-003614-63rzzos3	59	13	gene	gene	NN
cord-003614-63rzzos3	59	14	factor	factor	NN
cord-003614-63rzzos3	59	15	3	3	CD
cord-003614-63rzzos3	60	1	(	(	-LRB-
cord-003614-63rzzos3	60	2	ISGF3	isgf3	NN
cord-003614-63rzzos3	60	3	)	)	-RRB-
cord-003614-63rzzos3	60	4	.	.	.
cord-003614-63rzzos3	61	1	In	in	IN
cord-003614-63rzzos3	61	2	the	the	DT
cord-003614-63rzzos3	61	3	nucleus	nucleus	NN
cord-003614-63rzzos3	61	4	,	,	,
cord-003614-63rzzos3	61	5	ISGF3	isgf3	PRP
cord-003614-63rzzos3	61	6	induces	induce	VBZ
cord-003614-63rzzos3	61	7	the	the	DT
cord-003614-63rzzos3	61	8	transcription	transcription	NN
cord-003614-63rzzos3	61	9	of	of	IN
cord-003614-63rzzos3	61	10	interferon	interferon	NN
cord-003614-63rzzos3	61	11	-	-	HYPH
cord-003614-63rzzos3	61	12	stimulated	stimulate	VBN
cord-003614-63rzzos3	61	13	genes	gene	NNS
cord-003614-63rzzos3	61	14	including	include	VBG
cord-003614-63rzzos3	61	15	ISG15	ISG15	NNP
cord-003614-63rzzos3	61	16	,	,	,
cord-003614-63rzzos3	61	17	MX1	MX1	NNP
cord-003614-63rzzos3	61	18	,	,	,
cord-003614-63rzzos3	61	19	MX2	MX2	NNP
cord-003614-63rzzos3	61	20	,	,	,
cord-003614-63rzzos3	61	21	PKR	PKR	NNP
cord-003614-63rzzos3	61	22	,	,	,
cord-003614-63rzzos3	61	23	IRF7	IRF7	NNP
cord-003614-63rzzos3	61	24	,	,	,
cord-003614-63rzzos3	61	25	OAS1	OAS1	NNP
cord-003614-63rzzos3	61	26	,	,	,
cord-003614-63rzzos3	61	27	OAS2	OAS2	NNP
cord-003614-63rzzos3	61	28	and	and	CC
cord-003614-63rzzos3	61	29	OASL	OASL	NNP
cord-003614-63rzzos3	61	30	.	.	.
cord-003614-63rzzos3	62	1	IRF7	IRF7	NNP
cord-003614-63rzzos3	62	2	also	also	RB
cord-003614-63rzzos3	62	3	acts	act	VBZ
cord-003614-63rzzos3	62	4	in	in	IN
cord-003614-63rzzos3	62	5	a	a	DT
cord-003614-63rzzos3	62	6	positive	positive	JJ
cord-003614-63rzzos3	62	7	feedback	feedback	NN
cord-003614-63rzzos3	62	8	loop	loop	NN
cord-003614-63rzzos3	62	9	to	to	TO
cord-003614-63rzzos3	62	10	stimulate	stimulate	VB
cord-003614-63rzzos3	62	11	IFN	IFN	NNP
cord-003614-63rzzos3	62	12	-	-	HYPH
cord-003614-63rzzos3	62	13	I	-PRON-	PRP
cord-003614-63rzzos3	62	14	expression	expression	NN
cord-003614-63rzzos3	62	15	.	.	.
cord-003614-63rzzos3	63	1	Columns	column	NNS
cord-003614-63rzzos3	63	2	behind	behind	IN
cord-003614-63rzzos3	63	3	the	the	DT
cord-003614-63rzzos3	63	4	gene	gene	NN
cord-003614-63rzzos3	63	5	symbols	symbol	NNS
cord-003614-63rzzos3	63	6	display	display	VBP
cord-003614-63rzzos3	63	7	fold	fold	JJ
cord-003614-63rzzos3	63	8	changes	change	NNS
cord-003614-63rzzos3	63	9	in	in	IN
cord-003614-63rzzos3	63	10	three	three	CD
cord-003614-63rzzos3	63	11	different	different	JJ
cord-003614-63rzzos3	63	12	stages	stage	NNS
cord-003614-63rzzos3	63	13	of	of	IN
cord-003614-63rzzos3	63	14	CDV	CDV	NNP
cord-003614-63rzzos3	63	15	-	-	HYPH
cord-003614-63rzzos3	63	16	infection	infection	NN
cord-003614-63rzzos3	63	17	(	(	-LRB-
cord-003614-63rzzos3	63	18	acute	acute	JJ
cord-003614-63rzzos3	63	19	;	;	:
cord-003614-63rzzos3	63	20	subacute	subacute	JJ
cord-003614-63rzzos3	63	21	;	;	:
cord-003614-63rzzos3	63	22	chronic	chronic	JJ
cord-003614-63rzzos3	63	23	)	)	-RRB-
cord-003614-63rzzos3	63	24	.	.	.
cord-003614-63rzzos3	64	1	Fold	fold	JJ
cord-003614-63rzzos3	64	2	changes	change	NNS
cord-003614-63rzzos3	64	3	are	be	VBP
cord-003614-63rzzos3	64	4	shown	show	VBN
cord-003614-63rzzos3	64	5	on	on	IN
cord-003614-63rzzos3	64	6	a	a	DT
cord-003614-63rzzos3	64	7	logarithmic	logarithmic	JJ
cord-003614-63rzzos3	64	8	scale	scale	NN
cord-003614-63rzzos3	64	9	.	.	.
cord-003614-63rzzos3	65	1	(	(	-LRB-
cord-003614-63rzzos3	65	2	NFκB	NFκB	NNP
cord-003614-63rzzos3	65	3	,	,	,
cord-003614-63rzzos3	65	4	IRF1	IRF1	NNP
cord-003614-63rzzos3	65	5	,	,	,
cord-003614-63rzzos3	65	6	IRF3	IRF3	NNP
cord-003614-63rzzos3	65	7	,	,	,
cord-003614-63rzzos3	65	8	IRF5	IRF5	NNP
cord-003614-63rzzos3	65	9	,	,	,
cord-003614-63rzzos3	65	10	IRF7	IRF7	NNP
cord-003614-63rzzos3	65	11	)	)	-RRB-
cord-003614-63rzzos3	65	12	.	.	.
cord-003614-63rzzos3	66	1	These	these	DT
cord-003614-63rzzos3	66	2	transcription	transcription	NN
cord-003614-63rzzos3	66	3	factors	factor	NNS
cord-003614-63rzzos3	66	4	translocate	translocate	VBP
cord-003614-63rzzos3	66	5	into	into	IN
cord-003614-63rzzos3	66	6	the	the	DT
cord-003614-63rzzos3	66	7	nucleus	nucleus	NN
cord-003614-63rzzos3	66	8	and	and	CC
cord-003614-63rzzos3	66	9	induce	induce	VB
cord-003614-63rzzos3	66	10	IFN	IFN	NNP
cord-003614-63rzzos3	66	11	-	-	HYPH
cord-003614-63rzzos3	66	12	I	-PRON-	PRP
cord-003614-63rzzos3	66	13	expression	expression	NN
cord-003614-63rzzos3	66	14	.	.	.
cord-003614-63rzzos3	67	1	Right	right	JJ
cord-003614-63rzzos3	67	2	side	side	NN
cord-003614-63rzzos3	67	3	:	:	:
cord-003614-63rzzos3	67	4	Receptor	receptor	NN
cord-003614-63rzzos3	67	5	binding	binding	NN
cord-003614-63rzzos3	67	6	of	of	IN
cord-003614-63rzzos3	67	7	IFN	IFN	NNP
cord-003614-63rzzos3	68	1	-I	-I	NNP
cord-003614-63rzzos3	68	2	activates	activate	VBZ
cord-003614-63rzzos3	68	3	the	the	DT
cord-003614-63rzzos3	68	4	JAK	JAK	NNP
cord-003614-63rzzos3	68	5	-	-	HYPH
cord-003614-63rzzos3	68	6	STAT	STAT	NNP
cord-003614-63rzzos3	68	7	signaling	signal	VBG
cord-003614-63rzzos3	68	8	pathway	pathway	NN
cord-003614-63rzzos3	68	9	leading	lead	VBG
cord-003614-63rzzos3	68	10	to	to	IN
cord-003614-63rzzos3	68	11	the	the	DT
cord-003614-63rzzos3	68	12	formation	formation	NN
cord-003614-63rzzos3	68	13	of	of	IN
cord-003614-63rzzos3	68	14	STAT1	stat1	NN
cord-003614-63rzzos3	68	15	/	/	SYM
cord-003614-63rzzos3	68	16	STAT2	STAT2	NNS
cord-003614-63rzzos3	68	17	heterodimers	heterodimer	NNS
cord-003614-63rzzos3	68	18	in	in	IN
cord-003614-63rzzos3	68	19	the	the	DT
cord-003614-63rzzos3	68	20	cytoplasm	cytoplasm	NN
cord-003614-63rzzos3	68	21	.	.	.
cord-003614-63rzzos3	69	1	These	these	DT
cord-003614-63rzzos3	69	2	heterodimers	heterodimer	NNS
cord-003614-63rzzos3	69	3	form	form	VBP
cord-003614-63rzzos3	69	4	a	a	DT
cord-003614-63rzzos3	69	5	complex	complex	NN
cord-003614-63rzzos3	69	6	with	with	IN
cord-003614-63rzzos3	69	7	IRF9	IRF9	NNP
cord-003614-63rzzos3	69	8	,	,	,
cord-003614-63rzzos3	69	9	termed	term	VBN
cord-003614-63rzzos3	69	10	interferon	interferon	NN
cord-003614-63rzzos3	69	11	-	-	HYPH
cord-003614-63rzzos3	69	12	stimulated	stimulate	VBN
cord-003614-63rzzos3	69	13	gene	gene	NN
cord-003614-63rzzos3	69	14	factor	factor	NN
cord-003614-63rzzos3	69	15	3	3	CD
cord-003614-63rzzos3	70	1	(	(	-LRB-
cord-003614-63rzzos3	70	2	ISGF3	isgf3	NN
cord-003614-63rzzos3	70	3	)	)	-RRB-
cord-003614-63rzzos3	70	4	.	.	.
cord-003614-63rzzos3	71	1	In	in	IN
cord-003614-63rzzos3	71	2	the	the	DT
cord-003614-63rzzos3	71	3	nucleus	nucleus	NN
cord-003614-63rzzos3	71	4	,	,	,
cord-003614-63rzzos3	71	5	ISGF3	isgf3	PRP
cord-003614-63rzzos3	71	6	induces	induce	VBZ
cord-003614-63rzzos3	71	7	the	the	DT
cord-003614-63rzzos3	71	8	transcription	transcription	NN
cord-003614-63rzzos3	71	9	of	of	IN
cord-003614-63rzzos3	71	10	interferon	interferon	NN
cord-003614-63rzzos3	71	11	-	-	HYPH
cord-003614-63rzzos3	71	12	stimulated	stimulate	VBN
cord-003614-63rzzos3	71	13	genes	gene	NNS
cord-003614-63rzzos3	71	14	including	include	VBG
cord-003614-63rzzos3	71	15	ISG15	ISG15	NNP
cord-003614-63rzzos3	71	16	,	,	,
cord-003614-63rzzos3	71	17	MX1	MX1	NNP
cord-003614-63rzzos3	71	18	,	,	,
cord-003614-63rzzos3	71	19	MX2	MX2	NNP
cord-003614-63rzzos3	71	20	,	,	,
cord-003614-63rzzos3	71	21	PKR	PKR	NNP
cord-003614-63rzzos3	71	22	,	,	,
cord-003614-63rzzos3	71	23	IRF7	IRF7	NNP
cord-003614-63rzzos3	71	24	,	,	,
cord-003614-63rzzos3	71	25	OAS1	OAS1	NNP
cord-003614-63rzzos3	71	26	,	,	,
cord-003614-63rzzos3	71	27	OAS2	OAS2	NNP
cord-003614-63rzzos3	71	28	and	and	CC
cord-003614-63rzzos3	71	29	OASL	OASL	NNP
cord-003614-63rzzos3	71	30	.	.	.
cord-003614-63rzzos3	72	1	IRF7	IRF7	NNP
cord-003614-63rzzos3	72	2	also	also	RB
cord-003614-63rzzos3	72	3	acts	act	VBZ
cord-003614-63rzzos3	72	4	in	in	IN
cord-003614-63rzzos3	72	5	a	a	DT
cord-003614-63rzzos3	72	6	positive	positive	JJ
cord-003614-63rzzos3	72	7	feedback	feedback	NN
cord-003614-63rzzos3	72	8	loop	loop	NN
cord-003614-63rzzos3	72	9	to	to	TO
cord-003614-63rzzos3	72	10	stimulate	stimulate	VB
cord-003614-63rzzos3	72	11	IFN	IFN	NNP
cord-003614-63rzzos3	72	12	-	-	HYPH
cord-003614-63rzzos3	72	13	I	-PRON-	PRP
cord-003614-63rzzos3	72	14	expression	expression	NN
cord-003614-63rzzos3	72	15	.	.	.
cord-003614-63rzzos3	73	1	Columns	column	NNS
cord-003614-63rzzos3	73	2	behind	behind	IN
cord-003614-63rzzos3	73	3	the	the	DT
cord-003614-63rzzos3	73	4	gene	gene	NN
cord-003614-63rzzos3	73	5	symbols	symbol	NNS
cord-003614-63rzzos3	73	6	display	display	VBP
cord-003614-63rzzos3	73	7	fold	fold	JJ
cord-003614-63rzzos3	73	8	changes	change	NNS
cord-003614-63rzzos3	73	9	in	in	IN
cord-003614-63rzzos3	73	10	three	three	CD
cord-003614-63rzzos3	73	11	different	different	JJ
cord-003614-63rzzos3	73	12	stages	stage	NNS
cord-003614-63rzzos3	73	13	of	of	IN
cord-003614-63rzzos3	73	14	CDV	CDV	NNP
cord-003614-63rzzos3	73	15	-	-	HYPH
cord-003614-63rzzos3	73	16	infection	infection	NN
cord-003614-63rzzos3	73	17	(	(	-LRB-
cord-003614-63rzzos3	73	18	acute	acute	JJ
cord-003614-63rzzos3	73	19	;	;	:
cord-003614-63rzzos3	73	20	subacute	subacute	JJ
cord-003614-63rzzos3	73	21	;	;	:
cord-003614-63rzzos3	73	22	chronic	chronic	JJ
cord-003614-63rzzos3	73	23	)	)	-RRB-
cord-003614-63rzzos3	73	24	.	.	.
cord-003614-63rzzos3	74	1	Fold	fold	JJ
cord-003614-63rzzos3	74	2	changes	change	NNS
cord-003614-63rzzos3	74	3	are	be	VBP
cord-003614-63rzzos3	74	4	shown	show	VBN
cord-003614-63rzzos3	74	5	on	on	IN
cord-003614-63rzzos3	74	6	a	a	DT
cord-003614-63rzzos3	74	7	logarithmic	logarithmic	JJ
cord-003614-63rzzos3	74	8	scale	scale	NN
cord-003614-63rzzos3	74	9	.	.	.
cord-003614-63rzzos3	74	10	 	 	_SP
cord-003614-63rzzos3	75	1	Lesions	lesion	NNS
cord-003614-63rzzos3	75	2	(	(	-LRB-
cord-003614-63rzzos3	75	3	130	130	CD
cord-003614-63rzzos3	75	4	)	)	-RRB-
cord-003614-63rzzos3	75	5	found	find	VBN
cord-003614-63rzzos3	75	6	in	in	IN
cord-003614-63rzzos3	75	7	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	75	8	tissue	tissue	NN
cord-003614-63rzzos3	75	9	of	of	IN
cord-003614-63rzzos3	75	10	15	15	CD
cord-003614-63rzzos3	75	11	CDV	CDV	NNP
cord-003614-63rzzos3	75	12	-	-	HYPH
cord-003614-63rzzos3	75	13	infected	infect	VBN
cord-003614-63rzzos3	75	14	dogs	dog	NNS
cord-003614-63rzzos3	75	15	were	be	VBD
cord-003614-63rzzos3	75	16	analyzed	analyze	VBN
cord-003614-63rzzos3	75	17	using	use	VBG
cord-003614-63rzzos3	75	18	HE	HE	NNP
cord-003614-63rzzos3	75	19	-	-	:
cord-003614-63rzzos3	75	20	and	and	CC
cord-003614-63rzzos3	75	21	LFB	LFB	NNP
cord-003614-63rzzos3	75	22	-	-	HYPH
cord-003614-63rzzos3	75	23	stainings	staining	NNS
cord-003614-63rzzos3	75	24	and	and	CC
cord-003614-63rzzos3	75	25	CDV	CDV	NNP
cord-003614-63rzzos3	75	26	immunohistochemistry	immunohistochemistry	NN
cord-003614-63rzzos3	75	27	.	.	.
cord-003614-63rzzos3	76	1	In	in	IN
cord-003614-63rzzos3	76	2	16	16	CD
cord-003614-63rzzos3	76	3	lesions	lesion	NNS
cord-003614-63rzzos3	76	4	,	,	,
cord-003614-63rzzos3	76	5	CDV	CDV	NNP
cord-003614-63rzzos3	76	6	antigen	antigen	NN
cord-003614-63rzzos3	76	7	changes	change	NNS
cord-003614-63rzzos3	76	8	but	but	CC
cord-003614-63rzzos3	76	9	not	not	RB
cord-003614-63rzzos3	76	10	histological	histological	JJ
cord-003614-63rzzos3	76	11	ones	one	NNS
cord-003614-63rzzos3	76	12	were	be	VBD
cord-003614-63rzzos3	76	13	detected	detect	VBN
cord-003614-63rzzos3	76	14	(	(	-LRB-
cord-003614-63rzzos3	76	15	group	group	NN
cord-003614-63rzzos3	76	16	2	2	CD
cord-003614-63rzzos3	76	17	)	)	-RRB-
cord-003614-63rzzos3	76	18	.	.	.
cord-003614-63rzzos3	77	1	Twenty	twenty	CD
cord-003614-63rzzos3	77	2	-	-	HYPH
cord-003614-63rzzos3	77	3	six	six	CD
cord-003614-63rzzos3	77	4	acute	acute	JJ
cord-003614-63rzzos3	77	5	lesions	lesion	NNS
cord-003614-63rzzos3	77	6	were	be	VBD
cord-003614-63rzzos3	77	7	characterized	characterize	VBN
cord-003614-63rzzos3	77	8	by	by	IN
cord-003614-63rzzos3	77	9	white	white	JJ
cord-003614-63rzzos3	77	10	matter	matter	NN
cord-003614-63rzzos3	77	11	vacuolation	vacuolation	NN
cord-003614-63rzzos3	77	12	and	and	CC
cord-003614-63rzzos3	77	13	absence	absence	NN
cord-003614-63rzzos3	77	14	of	of	IN
cord-003614-63rzzos3	77	15	demyelination	demyelination	NN
cord-003614-63rzzos3	77	16	(	(	-LRB-
cord-003614-63rzzos3	77	17	group	group	NN
cord-003614-63rzzos3	77	18	3	3	CD
cord-003614-63rzzos3	77	19	)	)	-RRB-
cord-003614-63rzzos3	77	20	.	.	.
cord-003614-63rzzos3	78	1	Forty	forty	CD
cord-003614-63rzzos3	78	2	-	-	HYPH
cord-003614-63rzzos3	78	3	eight	eight	CD
cord-003614-63rzzos3	78	4	subacute	subacute	JJ
cord-003614-63rzzos3	78	5	lesions	lesion	NNS
cord-003614-63rzzos3	78	6	showed	show	VBD
cord-003614-63rzzos3	78	7	demyelination	demyelination	NN
cord-003614-63rzzos3	78	8	in	in	IN
cord-003614-63rzzos3	78	9	the	the	DT
cord-003614-63rzzos3	78	10	LFB	LFB	NNP
cord-003614-63rzzos3	78	11	-	-	HYPH
cord-003614-63rzzos3	78	12	staining	staining	NN
cord-003614-63rzzos3	78	13	but	but	CC
cord-003614-63rzzos3	78	14	no	no	DT
cord-003614-63rzzos3	78	15	inflammatory	inflammatory	JJ
cord-003614-63rzzos3	78	16	cell	cell	NN
cord-003614-63rzzos3	78	17	infiltration	infiltration	NN
cord-003614-63rzzos3	78	18	in	in	IN
cord-003614-63rzzos3	78	19	the	the	DT
cord-003614-63rzzos3	78	20	HE	HE	NNP
cord-003614-63rzzos3	78	21	-	-	HYPH
cord-003614-63rzzos3	78	22	staining	staining	NN
cord-003614-63rzzos3	78	23	(	(	-LRB-
cord-003614-63rzzos3	78	24	group	group	NN
cord-003614-63rzzos3	78	25	4	4	CD
cord-003614-63rzzos3	78	26	)	)	-RRB-
cord-003614-63rzzos3	78	27	.	.	.
cord-003614-63rzzos3	79	1	Forty	forty	CD
cord-003614-63rzzos3	79	2	chronic	chronic	JJ
cord-003614-63rzzos3	79	3	lesions	lesion	NNS
cord-003614-63rzzos3	79	4	demonstrated	demonstrate	VBD
cord-003614-63rzzos3	79	5	advanced	advanced	JJ
cord-003614-63rzzos3	79	6	demyelination	demyelination	NN
cord-003614-63rzzos3	79	7	,	,	,
cord-003614-63rzzos3	79	8	perivascular	perivascular	JJ
cord-003614-63rzzos3	79	9	cuffing	cuffing	NN
cord-003614-63rzzos3	79	10	and	and	CC
cord-003614-63rzzos3	79	11	lymphocytes	lymphocyte	NNS
cord-003614-63rzzos3	79	12	in	in	IN
cord-003614-63rzzos3	79	13	the	the	DT
cord-003614-63rzzos3	79	14	parenchyma	parenchyma	NN
cord-003614-63rzzos3	79	15	(	(	-LRB-
cord-003614-63rzzos3	79	16	group	group	NN
cord-003614-63rzzos3	79	17	5	5	CD
cord-003614-63rzzos3	79	18	)	)	-RRB-
cord-003614-63rzzos3	79	19	.	.	.
cord-003614-63rzzos3	80	1	In	in	IN
cord-003614-63rzzos3	80	2	addition	addition	NN
cord-003614-63rzzos3	80	3	,	,	,
cord-003614-63rzzos3	80	4	53	53	CD
cord-003614-63rzzos3	80	5	areas	area	NNS
cord-003614-63rzzos3	80	6	were	be	VBD
cord-003614-63rzzos3	80	7	randomly	randomly	RB
cord-003614-63rzzos3	80	8	selected	select	VBN
cord-003614-63rzzos3	80	9	in	in	IN
cord-003614-63rzzos3	80	10	the	the	DT
cord-003614-63rzzos3	80	11	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	80	12	white	white	JJ
cord-003614-63rzzos3	80	13	matter	matter	NN
cord-003614-63rzzos3	80	14	of	of	IN
cord-003614-63rzzos3	80	15	six	six	CD
cord-003614-63rzzos3	80	16	control	control	NN
cord-003614-63rzzos3	80	17	dogs	dog	NNS
cord-003614-63rzzos3	80	18	for	for	IN
cord-003614-63rzzos3	80	19	evaluation	evaluation	NN
cord-003614-63rzzos3	80	20	(	(	-LRB-
cord-003614-63rzzos3	80	21	group	group	NN
cord-003614-63rzzos3	80	22	1	1	CD
cord-003614-63rzzos3	80	23	)	)	-RRB-
cord-003614-63rzzos3	80	24	.	.	.
cord-003614-63rzzos3	81	1	Representative	representative	JJ
cord-003614-63rzzos3	81	2	pictures	picture	NNS
cord-003614-63rzzos3	81	3	of	of	IN
cord-003614-63rzzos3	81	4	the	the	DT
cord-003614-63rzzos3	81	5	investigated	investigate	VBN
cord-003614-63rzzos3	81	6	lesions	lesion	NNS
cord-003614-63rzzos3	81	7	are	be	VBP
cord-003614-63rzzos3	81	8	shown	show	VBN
cord-003614-63rzzos3	81	9	in	in	IN
cord-003614-63rzzos3	81	10	Figure	Figure	NNP
cord-003614-63rzzos3	81	11	 	 	_SP
cord-003614-63rzzos3	82	1	In	in	IN
cord-003614-63rzzos3	82	2	general	general	JJ
cord-003614-63rzzos3	82	3	,	,	,
cord-003614-63rzzos3	82	4	immunohistochemical	immunohistochemical	JJ
cord-003614-63rzzos3	82	5	analysis	analysis	NN
cord-003614-63rzzos3	82	6	detected	detect	VBD
cord-003614-63rzzos3	82	7	an	an	DT
cord-003614-63rzzos3	82	8	increase	increase	NN
cord-003614-63rzzos3	82	9	in	in	IN
cord-003614-63rzzos3	82	10	the	the	DT
cord-003614-63rzzos3	82	11	protein	protein	NN
cord-003614-63rzzos3	82	12	expression	expression	NN
cord-003614-63rzzos3	82	13	of	of	IN
cord-003614-63rzzos3	82	14	all	all	DT
cord-003614-63rzzos3	82	15	investigated	investigate	VBN
cord-003614-63rzzos3	82	16	IFN	IFN	NNP
cord-003614-63rzzos3	82	17	-	-	HYPH
cord-003614-63rzzos3	82	18	I	I	NNP
cord-003614-63rzzos3	82	19	pathway	pathway	NN
cord-003614-63rzzos3	82	20	members	member	NNS
cord-003614-63rzzos3	82	21	in	in	IN
cord-003614-63rzzos3	82	22	CDV	CDV	NNP
cord-003614-63rzzos3	82	23	-	-	HYPH
cord-003614-63rzzos3	82	24	induced	induce	VBN
cord-003614-63rzzos3	82	25	white	white	JJ
cord-003614-63rzzos3	82	26	matter	matter	NN
cord-003614-63rzzos3	82	27	lesions	lesion	NNS
cord-003614-63rzzos3	82	28	(	(	-LRB-
cord-003614-63rzzos3	82	29	Figures	figure	NNS
cord-003614-63rzzos3	82	30	3	3	CD
cord-003614-63rzzos3	82	31	and	and	CC
cord-003614-63rzzos3	82	32	4	4	CD
cord-003614-63rzzos3	82	33	,	,	,
cord-003614-63rzzos3	82	34	Table	table	NN
cord-003614-63rzzos3	82	35	2	2	CD
cord-003614-63rzzos3	82	36	,	,	,
cord-003614-63rzzos3	82	37	Figure	figure	NN
cord-003614-63rzzos3	82	38	S1	S1	NNP
cord-003614-63rzzos3	82	39	)	)	-RRB-
cord-003614-63rzzos3	82	40	.	.	.
cord-003614-63rzzos3	82	41	 	 	_SP
cord-003614-63rzzos3	83	1	In	in	IN
cord-003614-63rzzos3	83	2	general	general	JJ
cord-003614-63rzzos3	83	3	,	,	,
cord-003614-63rzzos3	83	4	immunohistochemical	immunohistochemical	JJ
cord-003614-63rzzos3	83	5	analysis	analysis	NN
cord-003614-63rzzos3	83	6	detected	detect	VBD
cord-003614-63rzzos3	83	7	an	an	DT
cord-003614-63rzzos3	83	8	increase	increase	NN
cord-003614-63rzzos3	83	9	in	in	IN
cord-003614-63rzzos3	83	10	the	the	DT
cord-003614-63rzzos3	83	11	protein	protein	NN
cord-003614-63rzzos3	83	12	expression	expression	NN
cord-003614-63rzzos3	83	13	of	of	IN
cord-003614-63rzzos3	83	14	all	all	DT
cord-003614-63rzzos3	83	15	investigated	investigate	VBN
cord-003614-63rzzos3	83	16	IFN	IFN	NNP
cord-003614-63rzzos3	83	17	-	-	HYPH
cord-003614-63rzzos3	83	18	I	I	NNP
cord-003614-63rzzos3	83	19	pathway	pathway	NN
cord-003614-63rzzos3	83	20	members	member	NNS
cord-003614-63rzzos3	83	21	in	in	IN
cord-003614-63rzzos3	83	22	CDV	CDV	NNP
cord-003614-63rzzos3	83	23	-	-	HYPH
cord-003614-63rzzos3	83	24	induced	induce	VBN
cord-003614-63rzzos3	83	25	white	white	JJ
cord-003614-63rzzos3	83	26	matter	matter	NN
cord-003614-63rzzos3	83	27	lesions	lesion	NNS
cord-003614-63rzzos3	83	28	(	(	-LRB-
cord-003614-63rzzos3	83	29	Figures	figure	NNS
cord-003614-63rzzos3	83	30	3	3	CD
cord-003614-63rzzos3	83	31	and	and	CC
cord-003614-63rzzos3	83	32	4	4	CD
cord-003614-63rzzos3	83	33	,	,	,
cord-003614-63rzzos3	83	34	Table	table	NN
cord-003614-63rzzos3	83	35	2	2	CD
cord-003614-63rzzos3	83	36	,	,	,
cord-003614-63rzzos3	83	37	Figure	figure	NN
cord-003614-63rzzos3	83	38	S1	S1	NNP
cord-003614-63rzzos3	83	39	)	)	-RRB-
cord-003614-63rzzos3	83	40	.	.	.
cord-003614-63rzzos3	84	1	A	a	DT
cord-003614-63rzzos3	84	2	statistically	statistically	RB
cord-003614-63rzzos3	84	3	significant	significant	JJ
cord-003614-63rzzos3	84	4	up	up	NN
cord-003614-63rzzos3	84	5	-	-	HYPH
cord-003614-63rzzos3	84	6	regulation	regulation	NN
cord-003614-63rzzos3	84	7	of	of	IN
cord-003614-63rzzos3	84	8	IRF3	IRF3	NNP
cord-003614-63rzzos3	84	9	protein	protein	NN
cord-003614-63rzzos3	84	10	expression	expression	NN
cord-003614-63rzzos3	84	11	was	be	VBD
cord-003614-63rzzos3	84	12	only	only	RB
cord-003614-63rzzos3	84	13	found	find	VBN
cord-003614-63rzzos3	84	14	in	in	IN
cord-003614-63rzzos3	84	15	group	group	NN
cord-003614-63rzzos3	84	16	2	2	CD
cord-003614-63rzzos3	84	17	lesions	lesion	NNS
cord-003614-63rzzos3	84	18	compared	compare	VBN
cord-003614-63rzzos3	84	19	to	to	IN
cord-003614-63rzzos3	84	20	controls	control	NNS
cord-003614-63rzzos3	84	21	(	(	-LRB-
cord-003614-63rzzos3	84	22	p	p	NN
cord-003614-63rzzos3	84	23	<	<	XX
cord-003614-63rzzos3	84	24	0.001	0.001	CD
cord-003614-63rzzos3	84	25	)	)	-RRB-
cord-003614-63rzzos3	84	26	.	.	.
cord-003614-63rzzos3	85	1	Endothelial	endothelial	JJ
cord-003614-63rzzos3	85	2	cells	cell	NNS
cord-003614-63rzzos3	85	3	,	,	,
cord-003614-63rzzos3	85	4	neurons	neuron	NNS
cord-003614-63rzzos3	85	5	and	and	CC
cord-003614-63rzzos3	85	6	glial	glial	JJ
cord-003614-63rzzos3	85	7	cells	cell	NNS
cord-003614-63rzzos3	85	8	were	be	VBD
cord-003614-63rzzos3	85	9	positive	positive	JJ
cord-003614-63rzzos3	85	10	for	for	IN
cord-003614-63rzzos3	85	11	IRF3	IRF3	NNP
cord-003614-63rzzos3	85	12	in	in	IN
cord-003614-63rzzos3	85	13	all	all	DT
cord-003614-63rzzos3	85	14	investigated	investigate	VBN
cord-003614-63rzzos3	85	15	groups	group	NNS
cord-003614-63rzzos3	85	16	.	.	.
cord-003614-63rzzos3	86	1	In	in	IN
cord-003614-63rzzos3	86	2	addition	addition	NN
cord-003614-63rzzos3	86	3	,	,	,
cord-003614-63rzzos3	86	4	perivascular	perivascular	NNP
cord-003614-63rzzos3	86	5	lymphocytes	lymphocyte	NNS
cord-003614-63rzzos3	86	6	present	present	JJ
cord-003614-63rzzos3	86	7	in	in	IN
cord-003614-63rzzos3	86	8	group	group	NN
cord-003614-63rzzos3	86	9	5	5	CD
cord-003614-63rzzos3	86	10	expressed	express	VBD
cord-003614-63rzzos3	86	11	IRF3	IRF3	NNP
cord-003614-63rzzos3	86	12	.	.	.
cord-003614-63rzzos3	87	1	IRF7	IRF7	NNP
cord-003614-63rzzos3	87	2	protein	protein	NN
cord-003614-63rzzos3	87	3	was	be	VBD
cord-003614-63rzzos3	87	4	not	not	RB
cord-003614-63rzzos3	87	5	expressed	express	VBN
cord-003614-63rzzos3	87	6	in	in	IN
cord-003614-63rzzos3	87	7	perivascular	perivascular	JJ
cord-003614-63rzzos3	87	8	lymphocytes	lymphocyte	NNS
cord-003614-63rzzos3	87	9	but	but	CC
cord-003614-63rzzos3	87	10	in	in	IN
cord-003614-63rzzos3	87	11	glial	glial	JJ
cord-003614-63rzzos3	87	12	cells	cell	NNS
cord-003614-63rzzos3	87	13	and	and	CC
cord-003614-63rzzos3	87	14	neurons	neuron	NNS
cord-003614-63rzzos3	87	15	in	in	IN
cord-003614-63rzzos3	87	16	infected	infected	JJ
cord-003614-63rzzos3	87	17	and	and	CC
cord-003614-63rzzos3	87	18	control	control	NN
cord-003614-63rzzos3	87	19	groups	group	NNS
cord-003614-63rzzos3	87	20	.	.	.
cord-003614-63rzzos3	88	1	There	there	EX
cord-003614-63rzzos3	88	2	was	be	VBD
cord-003614-63rzzos3	88	3	a	a	DT
cord-003614-63rzzos3	88	4	prominent	prominent	JJ
cord-003614-63rzzos3	88	5	staining	staining	NN
cord-003614-63rzzos3	88	6	in	in	IN
cord-003614-63rzzos3	88	7	the	the	DT
cord-003614-63rzzos3	88	8	granular	granular	JJ
cord-003614-63rzzos3	88	9	cell	cell	NN
cord-003614-63rzzos3	88	10	layer	layer	NN
cord-003614-63rzzos3	88	11	and	and	CC
cord-003614-63rzzos3	88	12	a	a	DT
cord-003614-63rzzos3	88	13	slight	slight	JJ
cord-003614-63rzzos3	88	14	staining	staining	NN
cord-003614-63rzzos3	88	15	of	of	IN
cord-003614-63rzzos3	88	16	Purkinje	Purkinje	NNP
cord-003614-63rzzos3	88	17	cells	cell	NNS
cord-003614-63rzzos3	88	18	.	.	.
cord-003614-63rzzos3	89	1	The	the	DT
cord-003614-63rzzos3	89	2	IRF7	IRF7	NNP
cord-003614-63rzzos3	89	3	protein	protein	NN
cord-003614-63rzzos3	89	4	expression	expression	NN
cord-003614-63rzzos3	89	5	was	be	VBD
cord-003614-63rzzos3	89	6	significantly	significantly	RB
cord-003614-63rzzos3	89	7	up	up	RB
cord-003614-63rzzos3	89	8	-	-	HYPH
cord-003614-63rzzos3	89	9	regulated	regulate	VBN
cord-003614-63rzzos3	89	10	in	in	IN
cord-003614-63rzzos3	89	11	acute	acute	JJ
cord-003614-63rzzos3	89	12	(	(	-LRB-
cord-003614-63rzzos3	89	13	p	p	NN
cord-003614-63rzzos3	89	14	=	=	SYM
cord-003614-63rzzos3	89	15	0.006	0.006	CD
cord-003614-63rzzos3	89	16	)	)	-RRB-
cord-003614-63rzzos3	89	17	,	,	,
cord-003614-63rzzos3	89	18	subacute	subacute	JJ
cord-003614-63rzzos3	89	19	(	(	-LRB-
cord-003614-63rzzos3	89	20	p	p	NN
cord-003614-63rzzos3	89	21	<	<	XX
cord-003614-63rzzos3	89	22	0.001	0.001	CD
cord-003614-63rzzos3	89	23	)	)	-RRB-
cord-003614-63rzzos3	89	24	and	and	CC
cord-003614-63rzzos3	89	25	chronic	chronic	JJ
cord-003614-63rzzos3	89	26	lesions	lesion	NNS
cord-003614-63rzzos3	89	27	(	(	-LRB-
cord-003614-63rzzos3	89	28	p	p	NN
cord-003614-63rzzos3	89	29	<	<	XX
cord-003614-63rzzos3	89	30	0.001	0.001	CD
cord-003614-63rzzos3	89	31	)	)	-RRB-
cord-003614-63rzzos3	89	32	and	and	CC
cord-003614-63rzzos3	89	33	continuously	continuously	RB
cord-003614-63rzzos3	89	34	increased	increase	VBD
cord-003614-63rzzos3	89	35	during	during	IN
cord-003614-63rzzos3	89	36	lesion	lesion	NN
cord-003614-63rzzos3	89	37	progression	progression	NN
cord-003614-63rzzos3	89	38	.	.	.
cord-003614-63rzzos3	90	1	STAT1	stat1	XX
cord-003614-63rzzos3	91	1	protein	protein	JJ
cord-003614-63rzzos3	91	2	expression	expression	NN
cord-003614-63rzzos3	91	3	was	be	VBD
cord-003614-63rzzos3	91	4	increased	increase	VBN
cord-003614-63rzzos3	91	5	at	at	IN
cord-003614-63rzzos3	91	6	all	all	DT
cord-003614-63rzzos3	91	7	stages	stage	NNS
cord-003614-63rzzos3	91	8	of	of	IN
cord-003614-63rzzos3	91	9	CDV	CDV	NNP
cord-003614-63rzzos3	91	10	-	-	HYPH
cord-003614-63rzzos3	91	11	induced	induce	VBN
cord-003614-63rzzos3	91	12	leukoencephalitis	leukoencephalitis	NNP
cord-003614-63rzzos3	91	13	(	(	-LRB-
cord-003614-63rzzos3	91	14	group	group	NN
cord-003614-63rzzos3	91	15	2	2	CD
cord-003614-63rzzos3	91	16	:	:	:
cord-003614-63rzzos3	91	17	p	p	NN
cord-003614-63rzzos3	91	18	=	=	SYM
cord-003614-63rzzos3	91	19	0.003	0.003	CD
cord-003614-63rzzos3	91	20	;	;	:
cord-003614-63rzzos3	91	21	Groups	group	NNS
cord-003614-63rzzos3	91	22	3	3	CD
cord-003614-63rzzos3	91	23	-	-	SYM
cord-003614-63rzzos3	91	24	5	5	CD
cord-003614-63rzzos3	91	25	:	:	:
cord-003614-63rzzos3	91	26	p	p	NN
cord-003614-63rzzos3	91	27	<	<	XX
cord-003614-63rzzos3	91	28	0.001	0.001	CD
cord-003614-63rzzos3	91	29	)	)	-RRB-
cord-003614-63rzzos3	91	30	.	.	.
cord-003614-63rzzos3	92	1	In	in	IN
cord-003614-63rzzos3	92	2	CDV	CDV	NNP
cord-003614-63rzzos3	92	3	-	-	HYPH
cord-003614-63rzzos3	92	4	infected	infect	VBN
cord-003614-63rzzos3	92	5	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	92	6	tissue	tissue	NN
cord-003614-63rzzos3	92	7	,	,	,
cord-003614-63rzzos3	92	8	STAT1	stat1	NN
cord-003614-63rzzos3	92	9	proteins	protein	NNS
cord-003614-63rzzos3	92	10	were	be	VBD
cord-003614-63rzzos3	92	11	mainly	mainly	RB
cord-003614-63rzzos3	92	12	detected	detect	VBN
cord-003614-63rzzos3	92	13	in	in	IN
cord-003614-63rzzos3	92	14	glial	glial	JJ
cord-003614-63rzzos3	92	15	cells	cell	NNS
cord-003614-63rzzos3	92	16	,	,	,
cord-003614-63rzzos3	92	17	whereas	whereas	IN
cord-003614-63rzzos3	92	18	only	only	RB
cord-003614-63rzzos3	92	19	a	a	DT
cord-003614-63rzzos3	92	20	few	few	JJ
cord-003614-63rzzos3	92	21	neurons	neuron	NNS
cord-003614-63rzzos3	92	22	and	and	CC
cord-003614-63rzzos3	92	23	endothelial	endothelial	JJ
cord-003614-63rzzos3	92	24	cells	cell	NNS
cord-003614-63rzzos3	92	25	expressed	express	VBD
cord-003614-63rzzos3	92	26	STAT1	stat1	NN
cord-003614-63rzzos3	92	27	and	and	CC
cord-003614-63rzzos3	92	28	perivascular	perivascular	NNP
cord-003614-63rzzos3	92	29	cells	cell	NNS
cord-003614-63rzzos3	92	30	were	be	VBD
cord-003614-63rzzos3	92	31	mainly	mainly	RB
cord-003614-63rzzos3	92	32	negative	negative	JJ
cord-003614-63rzzos3	92	33	.	.	.
cord-003614-63rzzos3	93	1	In	in	IN
cord-003614-63rzzos3	93	2	control	control	NN
cord-003614-63rzzos3	93	3	tissue	tissue	NN
cord-003614-63rzzos3	93	4	,	,	,
cord-003614-63rzzos3	93	5	only	only	RB
cord-003614-63rzzos3	93	6	single	single	JJ
cord-003614-63rzzos3	93	7	glial	glial	JJ
cord-003614-63rzzos3	93	8	cells	cell	NNS
cord-003614-63rzzos3	93	9	,	,	,
cord-003614-63rzzos3	93	10	as	as	RB
cord-003614-63rzzos3	93	11	well	well	RB
cord-003614-63rzzos3	93	12	as	as	IN
cord-003614-63rzzos3	93	13	some	some	DT
cord-003614-63rzzos3	93	14	neurons	neuron	NNS
cord-003614-63rzzos3	93	15	and	and	CC
cord-003614-63rzzos3	93	16	endothelial	endothelial	JJ
cord-003614-63rzzos3	93	17	cells	cell	NNS
cord-003614-63rzzos3	93	18	,	,	,
cord-003614-63rzzos3	93	19	slightly	slightly	RB
cord-003614-63rzzos3	93	20	expressed	express	VBN
cord-003614-63rzzos3	93	21	STAT1	stat1	NN
cord-003614-63rzzos3	93	22	.	.	.
cord-003614-63rzzos3	94	1	STAT2	STAT2	NNS
cord-003614-63rzzos3	94	2	protein	protein	NN
cord-003614-63rzzos3	94	3	expression	expression	NN
cord-003614-63rzzos3	94	4	was	be	VBD
cord-003614-63rzzos3	94	5	significantly	significantly	RB
cord-003614-63rzzos3	94	6	elevated	elevate	VBN
cord-003614-63rzzos3	94	7	only	only	RB
cord-003614-63rzzos3	94	8	in	in	IN
cord-003614-63rzzos3	94	9	chronic	chronic	JJ
cord-003614-63rzzos3	94	10	lesions	lesion	NNS
cord-003614-63rzzos3	94	11	(	(	-LRB-
cord-003614-63rzzos3	94	12	group	group	NN
cord-003614-63rzzos3	94	13	5	5	CD
cord-003614-63rzzos3	94	14	:	:	:
cord-003614-63rzzos3	94	15	p	p	NN
cord-003614-63rzzos3	94	16	=	=	SYM
cord-003614-63rzzos3	94	17	0.02	0.02	CD
cord-003614-63rzzos3	94	18	)	)	-RRB-
cord-003614-63rzzos3	94	19	.	.	.
cord-003614-63rzzos3	95	1	Perivascular	Perivascular	NNP
cord-003614-63rzzos3	95	2	lymphocytes	lymphocyte	NNS
cord-003614-63rzzos3	95	3	were	be	VBD
cord-003614-63rzzos3	95	4	negative	negative	JJ
cord-003614-63rzzos3	95	5	for	for	IN
cord-003614-63rzzos3	95	6	STAT2	STAT2	NNS
cord-003614-63rzzos3	95	7	,	,	,
cord-003614-63rzzos3	95	8	whereas	whereas	IN
cord-003614-63rzzos3	95	9	neurons	neuron	NNS
cord-003614-63rzzos3	95	10	,	,	,
cord-003614-63rzzos3	95	11	especially	especially	RB
cord-003614-63rzzos3	95	12	Purkinje	purkinje	JJ
cord-003614-63rzzos3	95	13	cells	cell	NNS
cord-003614-63rzzos3	95	14	and	and	CC
cord-003614-63rzzos3	95	15	glia	glia	NN
cord-003614-63rzzos3	95	16	cells	cell	NNS
cord-003614-63rzzos3	95	17	,	,	,
cord-003614-63rzzos3	95	18	expressed	express	VBD
cord-003614-63rzzos3	95	19	STAT2	STAT2	NNS
cord-003614-63rzzos3	95	20	with	with	IN
cord-003614-63rzzos3	95	21	a	a	DT
cord-003614-63rzzos3	95	22	strong	strong	JJ
cord-003614-63rzzos3	95	23	intensity	intensity	NN
cord-003614-63rzzos3	95	24	in	in	IN
cord-003614-63rzzos3	95	25	CDV	CDV	NNP
cord-003614-63rzzos3	95	26	-	-	HYPH
cord-003614-63rzzos3	95	27	infected	infect	VBN
cord-003614-63rzzos3	95	28	dogs	dog	NNS
cord-003614-63rzzos3	95	29	and	and	CC
cord-003614-63rzzos3	95	30	a	a	DT
cord-003614-63rzzos3	95	31	weak	weak	JJ
cord-003614-63rzzos3	95	32	intensity	intensity	NN
cord-003614-63rzzos3	95	33	in	in	IN
cord-003614-63rzzos3	95	34	control	control	NN
cord-003614-63rzzos3	95	35	dogs	dog	NNS
cord-003614-63rzzos3	95	36	.	.	.
cord-003614-63rzzos3	96	1	ISG15	ISG15	NNP
cord-003614-63rzzos3	97	1	,	,	,
cord-003614-63rzzos3	97	2	MX	MX	NNP
cord-003614-63rzzos3	97	3	and	and	CC
cord-003614-63rzzos3	97	4	PKR	PKR	NNP
cord-003614-63rzzos3	97	5	proteins	protein	NNS
cord-003614-63rzzos3	97	6	were	be	VBD
cord-003614-63rzzos3	97	7	significantly	significantly	RB
cord-003614-63rzzos3	97	8	increased	increase	VBN
cord-003614-63rzzos3	97	9	at	at	RB
cord-003614-63rzzos3	97	10	all	all	RB
cord-003614-63rzzos3	97	11	investigated	investigate	VBN
cord-003614-63rzzos3	97	12	stages	stage	NNS
cord-003614-63rzzos3	97	13	of	of	IN
cord-003614-63rzzos3	97	14	CDV	CDV	NNP
cord-003614-63rzzos3	97	15	-	-	HYPH
cord-003614-63rzzos3	97	16	induced	induce	VBN
cord-003614-63rzzos3	97	17	leukoencephalitis	leukoencephalitis	NNP
cord-003614-63rzzos3	97	18	(	(	-LRB-
cord-003614-63rzzos3	97	19	p	p	NN
cord-003614-63rzzos3	97	20	<	<	XX
cord-003614-63rzzos3	97	21	0.001	0.001	CD
cord-003614-63rzzos3	97	22	)	)	-RRB-
cord-003614-63rzzos3	97	23	.	.	.
cord-003614-63rzzos3	98	1	Perivascular	Perivascular	NNP
cord-003614-63rzzos3	98	2	lymphocytes	lymphocyte	NNS
cord-003614-63rzzos3	98	3	expressed	express	VBD
cord-003614-63rzzos3	98	4	MX	MX	NNP
cord-003614-63rzzos3	98	5	and	and	CC
cord-003614-63rzzos3	98	6	PKR	PKR	NNP
cord-003614-63rzzos3	98	7	proteins	protein	NNS
cord-003614-63rzzos3	98	8	but	but	CC
cord-003614-63rzzos3	98	9	not	not	RB
cord-003614-63rzzos3	98	10	ISG15	ISG15	NNP
cord-003614-63rzzos3	98	11	.	.	.
cord-003614-63rzzos3	99	1	MX	MX	NNP
cord-003614-63rzzos3	99	2	proteins	protein	NNS
cord-003614-63rzzos3	99	3	were	be	VBD
cord-003614-63rzzos3	99	4	also	also	RB
cord-003614-63rzzos3	99	5	detected	detect	VBN
cord-003614-63rzzos3	99	6	in	in	IN
cord-003614-63rzzos3	99	7	endothelial	endothelial	JJ
cord-003614-63rzzos3	99	8	cells	cell	NNS
cord-003614-63rzzos3	99	9	,	,	,
cord-003614-63rzzos3	99	10	neurons	neuron	NNS
cord-003614-63rzzos3	99	11	and	and	CC
cord-003614-63rzzos3	99	12	glial	glial	JJ
cord-003614-63rzzos3	99	13	cells	cell	NNS
cord-003614-63rzzos3	99	14	of	of	IN
cord-003614-63rzzos3	99	15	CDV	CDV	NNP
cord-003614-63rzzos3	99	16	-	-	HYPH
cord-003614-63rzzos3	99	17	infected	infect	VBN
cord-003614-63rzzos3	99	18	dogs	dog	NNS
cord-003614-63rzzos3	99	19	.	.	.
cord-003614-63rzzos3	100	1	In	in	IN
cord-003614-63rzzos3	100	2	control	control	NN
cord-003614-63rzzos3	100	3	tissue	tissue	NN
cord-003614-63rzzos3	100	4	,	,	,
cord-003614-63rzzos3	100	5	only	only	RB
cord-003614-63rzzos3	100	6	some	some	DT
cord-003614-63rzzos3	100	7	neurons	neuron	NNS
cord-003614-63rzzos3	100	8	and	and	CC
cord-003614-63rzzos3	100	9	endothelial	endothelial	JJ
cord-003614-63rzzos3	100	10	cells	cell	NNS
cord-003614-63rzzos3	100	11	showed	show	VBD
cord-003614-63rzzos3	100	12	a	a	DT
cord-003614-63rzzos3	100	13	mild	mild	JJ
cord-003614-63rzzos3	100	14	MX	MX	NNP
cord-003614-63rzzos3	100	15	expression	expression	NN
cord-003614-63rzzos3	100	16	.	.	.
cord-003614-63rzzos3	101	1	Furthermore	furthermore	RB
cord-003614-63rzzos3	101	2	,	,	,
cord-003614-63rzzos3	101	3	glial	glial	JJ
cord-003614-63rzzos3	101	4	cells	cell	NNS
cord-003614-63rzzos3	101	5	and	and	CC
cord-003614-63rzzos3	101	6	neurons	neuron	NNS
cord-003614-63rzzos3	101	7	,	,	,
cord-003614-63rzzos3	101	8	especially	especially	RB
cord-003614-63rzzos3	101	9	Purkinje	purkinje	JJ
cord-003614-63rzzos3	101	10	cells	cell	NNS
cord-003614-63rzzos3	101	11	and	and	CC
cord-003614-63rzzos3	101	12	some	some	DT
cord-003614-63rzzos3	101	13	endothelial	endothelial	JJ
cord-003614-63rzzos3	101	14	cells	cell	NNS
cord-003614-63rzzos3	101	15	,	,	,
cord-003614-63rzzos3	101	16	were	be	VBD
cord-003614-63rzzos3	101	17	positive	positive	JJ
cord-003614-63rzzos3	101	18	for	for	IN
cord-003614-63rzzos3	101	19	PKR	PKR	NNP
cord-003614-63rzzos3	101	20	in	in	IN
cord-003614-63rzzos3	101	21	CDV	CDV	NNP
cord-003614-63rzzos3	101	22	-	-	HYPH
cord-003614-63rzzos3	101	23	infected	infect	VBN
cord-003614-63rzzos3	101	24	dogs	dog	NNS
cord-003614-63rzzos3	101	25	.	.	.
cord-003614-63rzzos3	102	1	In	in	IN
cord-003614-63rzzos3	102	2	control	control	NN
cord-003614-63rzzos3	102	3	animals	animal	NNS
cord-003614-63rzzos3	102	4	,	,	,
cord-003614-63rzzos3	102	5	PKR	PKR	NNP
cord-003614-63rzzos3	102	6	proteins	protein	NNS
cord-003614-63rzzos3	102	7	were	be	VBD
cord-003614-63rzzos3	102	8	only	only	RB
cord-003614-63rzzos3	102	9	detected	detect	VBN
cord-003614-63rzzos3	102	10	in	in	IN
cord-003614-63rzzos3	102	11	neurons	neuron	NNS
cord-003614-63rzzos3	102	12	,	,	,
cord-003614-63rzzos3	102	13	especially	especially	RB
cord-003614-63rzzos3	102	14	Purkinje	purkinje	JJ
cord-003614-63rzzos3	102	15	cells	cell	NNS
cord-003614-63rzzos3	102	16	.	.	.
cord-003614-63rzzos3	103	1	ISG15	isg15	NN
cord-003614-63rzzos3	103	2	proteins	protein	NNS
cord-003614-63rzzos3	103	3	were	be	VBD
cord-003614-63rzzos3	103	4	detected	detect	VBN
cord-003614-63rzzos3	103	5	in	in	IN
cord-003614-63rzzos3	103	6	neurons	neuron	NNS
cord-003614-63rzzos3	103	7	,	,	,
cord-003614-63rzzos3	103	8	endothelial	endothelial	JJ
cord-003614-63rzzos3	103	9	cells	cell	NNS
cord-003614-63rzzos3	103	10	and	and	CC
cord-003614-63rzzos3	103	11	glial	glial	JJ
cord-003614-63rzzos3	103	12	cells	cell	NNS
cord-003614-63rzzos3	103	13	of	of	IN
cord-003614-63rzzos3	103	14	CDV	CDV	NNP
cord-003614-63rzzos3	103	15	-	-	HYPH
cord-003614-63rzzos3	103	16	infected	infect	VBN
cord-003614-63rzzos3	103	17	dogs	dog	NNS
cord-003614-63rzzos3	103	18	,	,	,
cord-003614-63rzzos3	103	19	whereas	whereas	IN
cord-003614-63rzzos3	103	20	control	control	NN
cord-003614-63rzzos3	103	21	animals	animal	NNS
cord-003614-63rzzos3	103	22	only	only	RB
cord-003614-63rzzos3	103	23	showed	show	VBD
cord-003614-63rzzos3	103	24	a	a	DT
cord-003614-63rzzos3	103	25	weak	weak	JJ
cord-003614-63rzzos3	103	26	ISG15	ISG15	NNP
cord-003614-63rzzos3	103	27	protein	protein	NN
cord-003614-63rzzos3	103	28	expression	expression	NN
cord-003614-63rzzos3	103	29	in	in	IN
cord-003614-63rzzos3	103	30	neurons	neuron	NNS
cord-003614-63rzzos3	103	31	and	and	CC
cord-003614-63rzzos3	103	32	endothelial	endothelial	JJ
cord-003614-63rzzos3	103	33	cells	cell	NNS
cord-003614-63rzzos3	103	34	.	.	.
cord-003614-63rzzos3	104	1	A	a	DT
cord-003614-63rzzos3	104	2	significant	significant	JJ
cord-003614-63rzzos3	104	3	up	up	NN
cord-003614-63rzzos3	104	4	-	-	HYPH
cord-003614-63rzzos3	104	5	regulation	regulation	NN
cord-003614-63rzzos3	104	6	of	of	IN
cord-003614-63rzzos3	104	7	OAS	OAS	NNP
cord-003614-63rzzos3	104	8	proteins	protein	NNS
cord-003614-63rzzos3	104	9	was	be	VBD
cord-003614-63rzzos3	104	10	found	find	VBN
cord-003614-63rzzos3	104	11	in	in	IN
cord-003614-63rzzos3	104	12	acute	acute	JJ
cord-003614-63rzzos3	104	13	(	(	-LRB-
cord-003614-63rzzos3	104	14	p	p	NN
cord-003614-63rzzos3	104	15	=	=	SYM
cord-003614-63rzzos3	104	16	0.008	0.008	CD
cord-003614-63rzzos3	104	17	)	)	-RRB-
cord-003614-63rzzos3	104	18	,	,	,
cord-003614-63rzzos3	104	19	subacute	subacute	JJ
cord-003614-63rzzos3	104	20	(	(	-LRB-
cord-003614-63rzzos3	104	21	p	p	NN
cord-003614-63rzzos3	104	22	<	<	XX
cord-003614-63rzzos3	104	23	0.001	0.001	CD
cord-003614-63rzzos3	104	24	)	)	-RRB-
cord-003614-63rzzos3	104	25	and	and	CC
cord-003614-63rzzos3	104	26	chronic	chronic	JJ
cord-003614-63rzzos3	104	27	lesions	lesion	NNS
cord-003614-63rzzos3	104	28	(	(	-LRB-
cord-003614-63rzzos3	104	29	p	p	NN
cord-003614-63rzzos3	104	30	=	=	SYM
cord-003614-63rzzos3	104	31	0.01	0.01	CD
cord-003614-63rzzos3	104	32	)	)	-RRB-
cord-003614-63rzzos3	104	33	but	but	CC
cord-003614-63rzzos3	104	34	not	not	RB
cord-003614-63rzzos3	104	35	in	in	IN
cord-003614-63rzzos3	104	36	CDV	CDV	NNP
cord-003614-63rzzos3	104	37	-	-	HYPH
cord-003614-63rzzos3	104	38	infected	infect	VBN
cord-003614-63rzzos3	104	39	tissue	tissue	NN
cord-003614-63rzzos3	104	40	without	without	IN
cord-003614-63rzzos3	104	41	histological	histological	JJ
cord-003614-63rzzos3	104	42	lesions	lesion	NNS
cord-003614-63rzzos3	104	43	(	(	-LRB-
cord-003614-63rzzos3	104	44	group	group	NN
cord-003614-63rzzos3	104	45	2	2	CD
cord-003614-63rzzos3	104	46	;	;	:
cord-003614-63rzzos3	104	47	p	p	NN
cord-003614-63rzzos3	104	48	=	=	SYM
cord-003614-63rzzos3	104	49	0.09	0.09	CD
cord-003614-63rzzos3	104	50	)	)	-RRB-
cord-003614-63rzzos3	104	51	.	.	.
cord-003614-63rzzos3	105	1	In	in	IN
cord-003614-63rzzos3	105	2	CDV	CDV	NNP
cord-003614-63rzzos3	105	3	-	-	HYPH
cord-003614-63rzzos3	105	4	infected	infect	VBN
cord-003614-63rzzos3	105	5	dogs	dog	NNS
cord-003614-63rzzos3	105	6	,	,	,
cord-003614-63rzzos3	105	7	OAS	OAS	NNP
cord-003614-63rzzos3	105	8	proteins	protein	NNS
cord-003614-63rzzos3	105	9	were	be	VBD
cord-003614-63rzzos3	105	10	detected	detect	VBN
cord-003614-63rzzos3	105	11	in	in	IN
cord-003614-63rzzos3	105	12	perivascular	perivascular	JJ
cord-003614-63rzzos3	105	13	lymphocytes	lymphocyte	NNS
cord-003614-63rzzos3	105	14	,	,	,
cord-003614-63rzzos3	105	15	endothelial	endothelial	JJ
cord-003614-63rzzos3	105	16	cells	cell	NNS
cord-003614-63rzzos3	105	17	,	,	,
cord-003614-63rzzos3	105	18	glial	glial	JJ
cord-003614-63rzzos3	105	19	cells	cell	NNS
cord-003614-63rzzos3	105	20	and	and	CC
cord-003614-63rzzos3	105	21	neurons	neuron	NNS
cord-003614-63rzzos3	105	22	.	.	.
cord-003614-63rzzos3	106	1	In	in	IN
cord-003614-63rzzos3	106	2	control	control	NN
cord-003614-63rzzos3	106	3	animals	animal	NNS
cord-003614-63rzzos3	106	4	,	,	,
cord-003614-63rzzos3	106	5	only	only	RB
cord-003614-63rzzos3	106	6	neurons	neuron	NNS
cord-003614-63rzzos3	106	7	and	and	CC
cord-003614-63rzzos3	106	8	endothelial	endothelial	JJ
cord-003614-63rzzos3	106	9	cells	cell	NNS
cord-003614-63rzzos3	106	10	expressed	express	VBD
cord-003614-63rzzos3	106	11	OAS	OAS	NNP
cord-003614-63rzzos3	106	12	proteins	protein	NNS
cord-003614-63rzzos3	106	13	.	.	.
cord-003614-63rzzos3	107	1	control	control	NNP
cord-003614-63rzzos3	107	2	dogs	dog	NNS
cord-003614-63rzzos3	107	3	;	;	:
cord-003614-63rzzos3	107	4	group	group	NN
cord-003614-63rzzos3	107	5	2	2	CD
cord-003614-63rzzos3	107	6	are	be	VBP
cord-003614-63rzzos3	107	7	foci	foci	JJ
cord-003614-63rzzos3	107	8	with	with	IN
cord-003614-63rzzos3	107	9	CDV	CDV	NNP
cord-003614-63rzzos3	107	10	antigen	antigen	NN
cord-003614-63rzzos3	107	11	expression	expression	NN
cord-003614-63rzzos3	107	12	but	but	CC
cord-003614-63rzzos3	107	13	without	without	IN
cord-003614-63rzzos3	107	14	histological	histological	JJ
cord-003614-63rzzos3	107	15	lesions	lesion	NNS
cord-003614-63rzzos3	107	16	;	;	:
cord-003614-63rzzos3	107	17	group	group	NN
cord-003614-63rzzos3	107	18	3	3	CD
cord-003614-63rzzos3	107	19	are	be	VBP
cord-003614-63rzzos3	107	20	acute	acute	JJ
cord-003614-63rzzos3	107	21	CDV	CDV	NNP
cord-003614-63rzzos3	107	22	lesions	lesion	NNS
cord-003614-63rzzos3	107	23	;	;	:
cord-003614-63rzzos3	107	24	group	group	NN
cord-003614-63rzzos3	107	25	4	4	CD
cord-003614-63rzzos3	107	26	are	be	VBP
cord-003614-63rzzos3	107	27	subacute	subacute	JJ
cord-003614-63rzzos3	107	28	foci	focus	NNS
cord-003614-63rzzos3	107	29	without	without	IN
cord-003614-63rzzos3	107	30	inflammation	inflammation	NN
cord-003614-63rzzos3	107	31	;	;	:
cord-003614-63rzzos3	107	32	group	group	NN
cord-003614-63rzzos3	107	33	5	5	CD
cord-003614-63rzzos3	107	34	are	be	VBP
cord-003614-63rzzos3	107	35	chronic	chronic	JJ
cord-003614-63rzzos3	107	36	CDV	CDV	NNP
cord-003614-63rzzos3	107	37	lesions	lesion	NNS
cord-003614-63rzzos3	107	38	with	with	IN
cord-003614-63rzzos3	107	39	inflammation	inflammation	NN
cord-003614-63rzzos3	107	40	.	.	.
cord-003614-63rzzos3	108	1	Shown	show	VBN
cord-003614-63rzzos3	108	2	are	be	VBP
cord-003614-63rzzos3	108	3	the	the	DT
cord-003614-63rzzos3	108	4	percentages	percentage	NNS
cord-003614-63rzzos3	108	5	of	of	IN
cord-003614-63rzzos3	108	6	the	the	DT
cord-003614-63rzzos3	108	7	immunopositive	immunopositive	JJ
cord-003614-63rzzos3	108	8	area	area	NN
cord-003614-63rzzos3	108	9	using	use	VBG
cord-003614-63rzzos3	108	10	box	box	NN
cord-003614-63rzzos3	108	11	plots	plot	NNS
cord-003614-63rzzos3	108	12	in	in	IN
cord-003614-63rzzos3	108	13	a	a	DT
cord-003614-63rzzos3	108	14	logarithmic	logarithmic	JJ
cord-003614-63rzzos3	108	15	scale	scale	NN
cord-003614-63rzzos3	108	16	and	and	CC
cord-003614-63rzzos3	108	17	significant	significant	JJ
cord-003614-63rzzos3	108	18	differences	difference	NNS
cord-003614-63rzzos3	108	19	between	between	IN
cord-003614-63rzzos3	108	20	the	the	DT
cord-003614-63rzzos3	108	21	CDV	CDV	NNP
cord-003614-63rzzos3	108	22	-	-	HYPH
cord-003614-63rzzos3	108	23	infected	infect	VBN
cord-003614-63rzzos3	108	24	groups	group	NNS
cord-003614-63rzzos3	108	25	2	2	CD
cord-003614-63rzzos3	108	26	-	-	SYM
cord-003614-63rzzos3	108	27	5	5	CD
cord-003614-63rzzos3	108	28	and	and	CC
cord-003614-63rzzos3	108	29	the	the	DT
cord-003614-63rzzos3	108	30	control	control	NN
cord-003614-63rzzos3	108	31	group	group	NN
cord-003614-63rzzos3	108	32	1	1	CD
cord-003614-63rzzos3	108	33	based	base	VBN
cord-003614-63rzzos3	108	34	on	on	IN
cord-003614-63rzzos3	108	35	Kruskal	Kruskal	NNP
cord-003614-63rzzos3	108	36	-	-	HYPH
cord-003614-63rzzos3	108	37	Wallis	Wallis	NNP
cord-003614-63rzzos3	108	38	-	-	HYPH
cord-003614-63rzzos3	108	39	tests	test	NNS
cord-003614-63rzzos3	108	40	and	and	CC
cord-003614-63rzzos3	108	41	Dunn	Dunn	NNP
cord-003614-63rzzos3	108	42	's	's	POS
cord-003614-63rzzos3	108	43	multiple	multiple	JJ
cord-003614-63rzzos3	108	44	comparison	comparison	NN
cord-003614-63rzzos3	108	45	tests	test	NNS
cord-003614-63rzzos3	108	46	.	.	.
cord-003614-63rzzos3	109	1	*	*	NFP
cord-003614-63rzzos3	109	2	p	p	XX
cord-003614-63rzzos3	109	3	<	<	XX
cord-003614-63rzzos3	109	4	0.05	0.05	CD
cord-003614-63rzzos3	109	5	;	;	:
cord-003614-63rzzos3	110	1	*	*	NFP
cord-003614-63rzzos3	110	2	*	*	NFP
cord-003614-63rzzos3	110	3	p	p	XX
cord-003614-63rzzos3	110	4	<	<	XX
cord-003614-63rzzos3	110	5	0.01	0.01	CD
cord-003614-63rzzos3	110	6	;	;	:
cord-003614-63rzzos3	111	1	*	*	NFP
cord-003614-63rzzos3	111	2	*	*	NFP
cord-003614-63rzzos3	111	3	*	*	NFP
cord-003614-63rzzos3	111	4	p	p	XX
cord-003614-63rzzos3	111	5	<	<	XX
cord-003614-63rzzos3	111	6	0.001	0.001	CD
cord-003614-63rzzos3	111	7	.	.	.
cord-003614-63rzzos3	111	8	 	 	_SP
cord-003614-63rzzos3	112	1	+	+	CC
cord-003614-63rzzos3	113	1	+	+	CC
cord-003614-63rzzos3	114	1	+	+	CC
cord-003614-63rzzos3	115	1	+	+	CC
cord-003614-63rzzos3	116	1	+	+	CC
cord-003614-63rzzos3	117	1	+	+	CC
cord-003614-63rzzos3	118	1	+	+	CC
cord-003614-63rzzos3	119	1	+	+	CC
cord-003614-63rzzos3	120	1	+	+	CC
cord-003614-63rzzos3	121	1	+	+	CC
cord-003614-63rzzos3	122	1	+	+	CC
cord-003614-63rzzos3	123	1	+	+	CC
cord-003614-63rzzos3	124	1	+	+	CC
cord-003614-63rzzos3	125	1	+	+	CC
cord-003614-63rzzos3	126	1	+	+	CC
cord-003614-63rzzos3	127	1	+	+	CC
cord-003614-63rzzos3	128	1	+	+	CC
cord-003614-63rzzos3	128	2	+	+	CC
cord-003614-63rzzos3	129	1	-	-	:
cord-003614-63rzzos3	129	2	+	+	SYM
cord-003614-63rzzos3	129	3	+	+	CC
cord-003614-63rzzos3	129	4	+	+	CC
cord-003614-63rzzos3	129	5	-	-	HYPH
cord-003614-63rzzos3	129	6	+	+	CC
cord-003614-63rzzos3	129	7	-	-	HYPH
cord-003614-63rzzos3	129	8	+	+	SYM
cord-003614-63rzzos3	129	9	+	+	CC
cord-003614-63rzzos3	129	10	-	-	HYPH
cord-003614-63rzzos3	129	11	Endothelial	endothelial	JJ
cord-003614-63rzzos3	129	12	cells	cell	NNS
cord-003614-63rzzos3	130	1	+	+	CC
cord-003614-63rzzos3	131	1	+	+	CC
cord-003614-63rzzos3	132	1	+	+	CC
cord-003614-63rzzos3	133	1	+	+	CC
cord-003614-63rzzos3	134	1	+	+	CC
cord-003614-63rzzos3	135	1	+	+	LS
cord-003614-63rzzos3	135	2	(	(	-LRB-
cord-003614-63rzzos3	135	3	+	+	NN
cord-003614-63rzzos3	135	4	)	)	-RRB-
cord-003614-63rzzos3	136	1	(	(	-LRB-
cord-003614-63rzzos3	136	2	+	+	NN
cord-003614-63rzzos3	136	3	)	)	-RRB-
cord-003614-63rzzos3	137	1	+	+	CC
cord-003614-63rzzos3	138	1	(	(	-LRB-
cord-003614-63rzzos3	138	2	+	+	CC
cord-003614-63rzzos3	138	3	)	)	-RRB-
cord-003614-63rzzos3	138	4	-	-	:
cord-003614-63rzzos3	138	5	-	-	:
cord-003614-63rzzos3	138	6	+	+	SYM
cord-003614-63rzzos3	138	7	+	+	CC
cord-003614-63rzzos3	138	8	(	(	-LRB-
cord-003614-63rzzos3	138	9	+	+	NN
cord-003614-63rzzos3	138	10	)	)	-RRB-
cord-003614-63rzzos3	139	1	+	+	CC
cord-003614-63rzzos3	140	1	+	+	LS
cord-003614-63rzzos3	140	2	(	(	-LRB-
cord-003614-63rzzos3	140	3	+	+	NN
cord-003614-63rzzos3	140	4	)	)	-RRB-
cord-003614-63rzzos3	141	1	+	+	CC
cord-003614-63rzzos3	142	1	+	+	LS
cord-003614-63rzzos3	142	2	(	(	-LRB-
cord-003614-63rzzos3	142	3	+	+	CC
cord-003614-63rzzos3	142	4	)	)	-RRB-
cord-003614-63rzzos3	142	5	-	-	.
cord-003614-63rzzos3	143	1	Spearman	Spearman	NNP
cord-003614-63rzzos3	143	2	's	's	POS
cord-003614-63rzzos3	143	3	rank	rank	NN
cord-003614-63rzzos3	143	4	correlation	correlation	NN
cord-003614-63rzzos3	143	5	coefficients	coefficient	NNS
cord-003614-63rzzos3	143	6	demonstrated	demonstrate	VBD
cord-003614-63rzzos3	143	7	a	a	DT
cord-003614-63rzzos3	143	8	moderate	moderate	JJ
cord-003614-63rzzos3	143	9	correlation	correlation	NN
cord-003614-63rzzos3	143	10	between	between	IN
cord-003614-63rzzos3	143	11	CDV	CDV	NNP
cord-003614-63rzzos3	143	12	antigen	antigen	NN
cord-003614-63rzzos3	143	13	and	and	CC
cord-003614-63rzzos3	143	14	STAT1	stat1	NN
cord-003614-63rzzos3	143	15	,	,	,
cord-003614-63rzzos3	143	16	ISG15	ISG15	NNP
cord-003614-63rzzos3	143	17	,	,	,
cord-003614-63rzzos3	143	18	MX	MX	NNP
cord-003614-63rzzos3	143	19	and	and	CC
cord-003614-63rzzos3	143	20	PKR	PKR	NNP
cord-003614-63rzzos3	143	21	protein	protein	NN
cord-003614-63rzzos3	143	22	expression	expression	NN
cord-003614-63rzzos3	143	23	(	(	-LRB-
cord-003614-63rzzos3	143	24	Table	Table	NNP
cord-003614-63rzzos3	143	25	3	3	CD
cord-003614-63rzzos3	143	26	)	)	-RRB-
cord-003614-63rzzos3	143	27	.	.	.
cord-003614-63rzzos3	144	1	CDV	CDV	NNP
cord-003614-63rzzos3	144	2	antigen	antigen	NN
cord-003614-63rzzos3	144	3	correlated	correlate	VBD
cord-003614-63rzzos3	144	4	only	only	RB
cord-003614-63rzzos3	144	5	weakly	weakly	RB
cord-003614-63rzzos3	144	6	with	with	IN
cord-003614-63rzzos3	144	7	IRF3	IRF3	NNP
cord-003614-63rzzos3	144	8	and	and	CC
cord-003614-63rzzos3	144	9	STAT2	STAT2	NNPS
cord-003614-63rzzos3	144	10	and	and	CC
cord-003614-63rzzos3	144	11	did	do	VBD
cord-003614-63rzzos3	144	12	not	not	RB
cord-003614-63rzzos3	144	13	correlate	correlate	VB
cord-003614-63rzzos3	144	14	with	with	IN
cord-003614-63rzzos3	144	15	IRF7	IRF7	NNP
cord-003614-63rzzos3	144	16	protein	protein	NN
cord-003614-63rzzos3	144	17	expression	expression	NN
cord-003614-63rzzos3	144	18	.	.	.
cord-003614-63rzzos3	145	1	IRF3	IRF3	NNP
cord-003614-63rzzos3	145	2	also	also	RB
cord-003614-63rzzos3	145	3	correlated	correlate	VBD
cord-003614-63rzzos3	145	4	weakly	weakly	RB
cord-003614-63rzzos3	145	5	with	with	IN
cord-003614-63rzzos3	145	6	STAT1	stat1	NN
cord-003614-63rzzos3	145	7	,	,	,
cord-003614-63rzzos3	145	8	OAS	OAS	NNP
cord-003614-63rzzos3	145	9	and	and	CC
cord-003614-63rzzos3	145	10	PKR	PKR	NNP
cord-003614-63rzzos3	145	11	.	.	.
cord-003614-63rzzos3	146	1	Moreover	moreover	RB
cord-003614-63rzzos3	146	2	,	,	,
cord-003614-63rzzos3	146	3	there	there	EX
cord-003614-63rzzos3	146	4	was	be	VBD
cord-003614-63rzzos3	146	5	a	a	DT
cord-003614-63rzzos3	146	6	weak	weak	JJ
cord-003614-63rzzos3	146	7	to	to	IN
cord-003614-63rzzos3	147	1	moderate	moderate	JJ
cord-003614-63rzzos3	147	2	correlation	correlation	NN
cord-003614-63rzzos3	147	3	between	between	IN
cord-003614-63rzzos3	147	4	STAT1	stat1	NN
cord-003614-63rzzos3	147	5	,	,	,
cord-003614-63rzzos3	147	6	ISG15	ISG15	NNP
cord-003614-63rzzos3	147	7	,	,	,
cord-003614-63rzzos3	147	8	MX	MX	NNP
cord-003614-63rzzos3	147	9	,	,	,
cord-003614-63rzzos3	147	10	OAS	OAS	NNP
cord-003614-63rzzos3	147	11	and	and	CC
cord-003614-63rzzos3	147	12	PKR	PKR	NNP
cord-003614-63rzzos3	147	13	,	,	,
cord-003614-63rzzos3	147	14	a	a	DT
cord-003614-63rzzos3	147	15	moderate	moderate	JJ
cord-003614-63rzzos3	147	16	correlation	correlation	NN
cord-003614-63rzzos3	147	17	between	between	IN
cord-003614-63rzzos3	147	18	IRF7	IRF7	NNP
cord-003614-63rzzos3	147	19	and	and	CC
cord-003614-63rzzos3	147	20	ISG15	ISG15	NNP
cord-003614-63rzzos3	147	21	,	,	,
cord-003614-63rzzos3	147	22	and	and	CC
cord-003614-63rzzos3	147	23	a	a	DT
cord-003614-63rzzos3	147	24	strong	strong	JJ
cord-003614-63rzzos3	147	25	correlation	correlation	NN
cord-003614-63rzzos3	147	26	between	between	IN
cord-003614-63rzzos3	147	27	ISG15	ISG15	NNP
cord-003614-63rzzos3	147	28	and	and	CC
cord-003614-63rzzos3	147	29	MX	MX	NNP
cord-003614-63rzzos3	147	30	(	(	-LRB-
cord-003614-63rzzos3	147	31	Table	Table	NNP
cord-003614-63rzzos3	147	32	3	3	CD
cord-003614-63rzzos3	147	33	)	)	-RRB-
cord-003614-63rzzos3	147	34	.	.	.
cord-003614-63rzzos3	147	35	 	 	_SP
cord-003614-63rzzos3	148	1	Double	double	JJ
cord-003614-63rzzos3	148	2	staining	staining	NN
cord-003614-63rzzos3	148	3	with	with	IN
cord-003614-63rzzos3	148	4	cellular	cellular	JJ
cord-003614-63rzzos3	148	5	markers	marker	NNS
cord-003614-63rzzos3	148	6	revealed	reveal	VBD
cord-003614-63rzzos3	148	7	a	a	DT
cord-003614-63rzzos3	148	8	STAT1	stat1	NN
cord-003614-63rzzos3	148	9	expression	expression	NN
cord-003614-63rzzos3	148	10	in	in	IN
cord-003614-63rzzos3	148	11	NogoA	NogoA	NNP
cord-003614-63rzzos3	148	12	+	+	CC
cord-003614-63rzzos3	148	13	oligodendrocytes	oligodendrocyte	NNS
cord-003614-63rzzos3	148	14	,	,	,
cord-003614-63rzzos3	148	15	GFAP	GFAP	NNP
cord-003614-63rzzos3	148	16	+	+	SYM
cord-003614-63rzzos3	148	17	astrocytes	astrocyte	NNS
cord-003614-63rzzos3	148	18	and	and	CC
cord-003614-63rzzos3	148	19	IBA1	IBA1	NNP
cord-003614-63rzzos3	148	20	+	+	CC
cord-003614-63rzzos3	148	21	microglia	microglia	NNS
cord-003614-63rzzos3	148	22	/	/	SYM
cord-003614-63rzzos3	148	23	macrophages	macrophage	NNS
cord-003614-63rzzos3	148	24	,	,	,
cord-003614-63rzzos3	148	25	which	which	WDT
cord-003614-63rzzos3	148	26	was	be	VBD
cord-003614-63rzzos3	148	27	limited	limit	VBN
cord-003614-63rzzos3	148	28	to	to	IN
cord-003614-63rzzos3	148	29	histological	histological	JJ
cord-003614-63rzzos3	148	30	lesions	lesion	NNS
cord-003614-63rzzos3	148	31	.	.	.
cord-003614-63rzzos3	149	1	STAT2	STAT2	NNS
cord-003614-63rzzos3	149	2	was	be	VBD
cord-003614-63rzzos3	149	3	detected	detect	VBN
cord-003614-63rzzos3	149	4	in	in	IN
cord-003614-63rzzos3	149	5	NogoA	NogoA	NNP
cord-003614-63rzzos3	149	6	+	+	CC
cord-003614-63rzzos3	149	7	oligodendrocytes	oligodendrocyte	NNS
cord-003614-63rzzos3	149	8	located	locate	VBN
cord-003614-63rzzos3	149	9	in	in	IN
cord-003614-63rzzos3	149	10	white	white	JJ
cord-003614-63rzzos3	149	11	matter	matter	NN
cord-003614-63rzzos3	149	12	lesions	lesion	NNS
cord-003614-63rzzos3	149	13	and	and	CC
cord-003614-63rzzos3	149	14	also	also	RB
cord-003614-63rzzos3	149	15	in	in	IN
cord-003614-63rzzos3	149	16	normal	normal	RB
cord-003614-63rzzos3	149	17	-	-	HYPH
cord-003614-63rzzos3	149	18	appearing	appear	VBG
cord-003614-63rzzos3	149	19	white	white	JJ
cord-003614-63rzzos3	149	20	matter	matter	NN
cord-003614-63rzzos3	149	21	.	.	.
cord-003614-63rzzos3	150	1	STAT2	STAT2	NNS
cord-003614-63rzzos3	150	2	was	be	VBD
cord-003614-63rzzos3	150	3	also	also	RB
cord-003614-63rzzos3	150	4	found	find	VBN
cord-003614-63rzzos3	150	5	in	in	IN
cord-003614-63rzzos3	150	6	activated	activate	VBN
cord-003614-63rzzos3	150	7	IBA1	IBA1	NNP
cord-003614-63rzzos3	150	8	+	+	CC
cord-003614-63rzzos3	150	9	microglia	microglia	NNP
cord-003614-63rzzos3	150	10	/	/	SYM
cord-003614-63rzzos3	150	11	macrophages	macrophage	NNS
cord-003614-63rzzos3	150	12	(	(	-LRB-
cord-003614-63rzzos3	150	13	gitter	gitter	NNP
cord-003614-63rzzos3	150	14	cells	cell	NNS
cord-003614-63rzzos3	150	15	)	)	-RRB-
cord-003614-63rzzos3	150	16	,	,	,
cord-003614-63rzzos3	150	17	which	which	WDT
cord-003614-63rzzos3	150	18	were	be	VBD
cord-003614-63rzzos3	150	19	present	present	JJ
cord-003614-63rzzos3	150	20	in	in	IN
cord-003614-63rzzos3	150	21	subacute	subacute	JJ
cord-003614-63rzzos3	150	22	and	and	CC
cord-003614-63rzzos3	150	23	chronic	chronic	JJ
cord-003614-63rzzos3	150	24	white	white	JJ
cord-003614-63rzzos3	150	25	matter	matter	NN
cord-003614-63rzzos3	150	26	lesions	lesion	NNS
cord-003614-63rzzos3	150	27	.	.	.
cord-003614-63rzzos3	151	1	MX	MX	NNP
cord-003614-63rzzos3	151	2	was	be	VBD
cord-003614-63rzzos3	151	3	expressed	express	VBN
cord-003614-63rzzos3	151	4	by	by	IN
cord-003614-63rzzos3	151	5	intralesional	intralesional	JJ
cord-003614-63rzzos3	151	6	GFAP	GFAP	NNP
cord-003614-63rzzos3	151	7	+	+	SYM
cord-003614-63rzzos3	151	8	astrocytes	astrocyte	NNS
cord-003614-63rzzos3	151	9	,	,	,
cord-003614-63rzzos3	152	1	NogoA	nogoa	JJ
cord-003614-63rzzos3	152	2	+	+	CC
cord-003614-63rzzos3	152	3	oligodendrocytes	oligodendrocyte	NNS
cord-003614-63rzzos3	152	4	and	and	CC
cord-003614-63rzzos3	152	5	IBA1	IBA1	NNP
cord-003614-63rzzos3	152	6	+	+	CC
cord-003614-63rzzos3	152	7	microglia	microglia	NNS
cord-003614-63rzzos3	152	8	/	/	SYM
cord-003614-63rzzos3	152	9	macrophages	macrophage	NNS
cord-003614-63rzzos3	152	10	.	.	.
cord-003614-63rzzos3	153	1	PKR	PKR	NNP
cord-003614-63rzzos3	153	2	was	be	VBD
cord-003614-63rzzos3	153	3	also	also	RB
cord-003614-63rzzos3	153	4	found	find	VBN
cord-003614-63rzzos3	153	5	in	in	IN
cord-003614-63rzzos3	153	6	intralesional	intralesional	JJ
cord-003614-63rzzos3	153	7	GFAP	GFAP	NNS
cord-003614-63rzzos3	153	8	+	+	SYM
cord-003614-63rzzos3	153	9	astrocytes	astrocyte	NNS
cord-003614-63rzzos3	153	10	and	and	CC
cord-003614-63rzzos3	153	11	some	some	DT
cord-003614-63rzzos3	153	12	NogoA	NogoA	NNP
cord-003614-63rzzos3	153	13	+	+	CC
cord-003614-63rzzos3	153	14	oligodendrocytes	oligodendrocyte	NNS
cord-003614-63rzzos3	153	15	but	but	CC
cord-003614-63rzzos3	153	16	not	not	RB
cord-003614-63rzzos3	153	17	in	in	IN
cord-003614-63rzzos3	153	18	IBA1	IBA1	NNP
cord-003614-63rzzos3	154	1	+	+	CC
cord-003614-63rzzos3	154	2	microglia	microglia	NN
cord-003614-63rzzos3	154	3	/	/	SYM
cord-003614-63rzzos3	154	4	macrophages	macrophage	NNS
cord-003614-63rzzos3	154	5	(	(	-LRB-
cord-003614-63rzzos3	154	6	Figure	figure	NN
cord-003614-63rzzos3	154	7	5	5	CD
cord-003614-63rzzos3	154	8	)	)	-RRB-
cord-003614-63rzzos3	154	9	.	.	.
cord-003614-63rzzos3	155	1	Immunofluorescence	immunofluorescence	NN
cord-003614-63rzzos3	155	2	double	double	RB
cord-003614-63rzzos3	155	3	-	-	HYPH
cord-003614-63rzzos3	155	4	staining	staining	NN
cord-003614-63rzzos3	155	5	was	be	VBD
cord-003614-63rzzos3	155	6	also	also	RB
cord-003614-63rzzos3	155	7	used	use	VBN
cord-003614-63rzzos3	155	8	to	to	TO
cord-003614-63rzzos3	155	9	determine	determine	VB
cord-003614-63rzzos3	155	10	the	the	DT
cord-003614-63rzzos3	155	11	infection	infection	NN
cord-003614-63rzzos3	155	12	status	status	NN
cord-003614-63rzzos3	155	13	of	of	IN
cord-003614-63rzzos3	155	14	cells	cell	NNS
cord-003614-63rzzos3	155	15	expressing	express	VBG
cord-003614-63rzzos3	155	16	STAT1	stat1	NN
cord-003614-63rzzos3	155	17	,	,	,
cord-003614-63rzzos3	155	18	STAT2	STAT2	NNS
cord-003614-63rzzos3	155	19	and	and	CC
cord-003614-63rzzos3	155	20	MX	MX	NNP
cord-003614-63rzzos3	155	21	.	.	.
cord-003614-63rzzos3	156	1	A	a	DT
cord-003614-63rzzos3	156	2	low	low	JJ
cord-003614-63rzzos3	156	3	number	number	NN
cord-003614-63rzzos3	156	4	of	of	IN
cord-003614-63rzzos3	156	5	CDV	CDV	NNP
cord-003614-63rzzos3	156	6	-	-	HYPH
cord-003614-63rzzos3	156	7	infected	infect	VBN
cord-003614-63rzzos3	156	8	cells	cell	NNS
cord-003614-63rzzos3	156	9	expressed	express	VBD
cord-003614-63rzzos3	156	10	STAT1	stat1	NN
cord-003614-63rzzos3	156	11	and	and	CC
cord-003614-63rzzos3	156	12	MX	MX	NNP
cord-003614-63rzzos3	156	13	.	.	.
cord-003614-63rzzos3	157	1	However	however	RB
cord-003614-63rzzos3	157	2	,	,	,
cord-003614-63rzzos3	157	3	CDV	CDV	NNP
cord-003614-63rzzos3	157	4	-	-	HYPH
cord-003614-63rzzos3	157	5	infected	infect	VBN
cord-003614-63rzzos3	157	6	cells	cell	NNS
cord-003614-63rzzos3	157	7	expressing	express	VBG
cord-003614-63rzzos3	157	8	STAT2	STAT2	NNS
cord-003614-63rzzos3	157	9	were	be	VBD
cord-003614-63rzzos3	157	10	nearly	nearly	RB
cord-003614-63rzzos3	157	11	absent	absent	JJ
cord-003614-63rzzos3	157	12	(	(	-LRB-
cord-003614-63rzzos3	157	13	Figure	Figure	NNP
cord-003614-63rzzos3	157	14	6	6	CD
cord-003614-63rzzos3	157	15	)	)	-RRB-
cord-003614-63rzzos3	157	16	.	.	.
cord-003614-63rzzos3	157	17	 	 	_SP
cord-003614-63rzzos3	158	1	The	the	DT
cord-003614-63rzzos3	158	2	present	present	JJ
cord-003614-63rzzos3	158	3	study	study	NN
cord-003614-63rzzos3	158	4	gives	give	VBZ
cord-003614-63rzzos3	158	5	an	an	DT
cord-003614-63rzzos3	158	6	overview	overview	NN
cord-003614-63rzzos3	158	7	of	of	IN
cord-003614-63rzzos3	158	8	the	the	DT
cord-003614-63rzzos3	158	9	protein	protein	NN
cord-003614-63rzzos3	158	10	expression	expression	NN
cord-003614-63rzzos3	158	11	of	of	IN
cord-003614-63rzzos3	158	12	selected	select	VBN
cord-003614-63rzzos3	158	13	IFN	IFN	NNP
cord-003614-63rzzos3	158	14	-	-	HYPH
cord-003614-63rzzos3	158	15	I	I	NNP
cord-003614-63rzzos3	158	16	pathway	pathway	NN
cord-003614-63rzzos3	158	17	members	member	NNS
cord-003614-63rzzos3	158	18	and	and	CC
cord-003614-63rzzos3	158	19	compares	compare	VBZ
cord-003614-63rzzos3	158	20	it	-PRON-	PRP
cord-003614-63rzzos3	158	21	with	with	IN
cord-003614-63rzzos3	158	22	existing	exist	VBG
cord-003614-63rzzos3	158	23	microarray	microarray	NN
cord-003614-63rzzos3	158	24	data	datum	NNS
cord-003614-63rzzos3	158	25	.	.	.
cord-003614-63rzzos3	159	1	Previous	previous	JJ
cord-003614-63rzzos3	159	2	studies	study	NNS
cord-003614-63rzzos3	159	3	often	often	RB
cord-003614-63rzzos3	159	4	investigated	investigate	VBD
cord-003614-63rzzos3	159	5	ISG	ISG	NNP
cord-003614-63rzzos3	159	6	expression	expression	NN
cord-003614-63rzzos3	159	7	in	in	IN
cord-003614-63rzzos3	159	8	cell	cell	NN
cord-003614-63rzzos3	159	9	cultures	culture	NNS
cord-003614-63rzzos3	159	10	,	,	,
cord-003614-63rzzos3	159	11	whereas	whereas	IN
cord-003614-63rzzos3	159	12	studies	study	NNS
cord-003614-63rzzos3	159	13	on	on	IN
cord-003614-63rzzos3	159	14	the	the	DT
cord-003614-63rzzos3	159	15	protein	protein	NN
cord-003614-63rzzos3	159	16	expression	expression	NN
cord-003614-63rzzos3	159	17	of	of	IN
cord-003614-63rzzos3	159	18	ISGs	isg	NNS
cord-003614-63rzzos3	159	19	in	in	IN
cord-003614-63rzzos3	159	20	a	a	DT
cord-003614-63rzzos3	159	21	naturally	naturally	RB
cord-003614-63rzzos3	159	22	occurring	occur	VBG
cord-003614-63rzzos3	159	23	animal	animal	NN
cord-003614-63rzzos3	159	24	disease	disease	NN
cord-003614-63rzzos3	159	25	are	be	VBP
cord-003614-63rzzos3	159	26	rare	rare	JJ
cord-003614-63rzzos3	159	27	[	[	-LRB-
cord-003614-63rzzos3	159	28	48	48	CD
cord-003614-63rzzos3	159	29	]	]	-RRB-
cord-003614-63rzzos3	159	30	[	[	-LRB-
cord-003614-63rzzos3	159	31	49	49	CD
cord-003614-63rzzos3	159	32	]	]	-RRB-
cord-003614-63rzzos3	159	33	[	[	-LRB-
cord-003614-63rzzos3	159	34	50	50	CD
cord-003614-63rzzos3	159	35	]	]	-RRB-
cord-003614-63rzzos3	159	36	[	[	-LRB-
cord-003614-63rzzos3	159	37	51	51	CD
cord-003614-63rzzos3	159	38	]	]	-RRB-
cord-003614-63rzzos3	159	39	[	[	-LRB-
cord-003614-63rzzos3	159	40	52	52	CD
cord-003614-63rzzos3	159	41	]	]	-RRB-
cord-003614-63rzzos3	159	42	.	.	.
cord-003614-63rzzos3	160	1	IRF3	IRF3	NNP
cord-003614-63rzzos3	160	2	plays	play	VBZ
cord-003614-63rzzos3	160	3	,	,	,
cord-003614-63rzzos3	160	4	together	together	RB
cord-003614-63rzzos3	160	5	with	with	IN
cord-003614-63rzzos3	160	6	the	the	DT
cord-003614-63rzzos3	160	7	closely	closely	RB
cord-003614-63rzzos3	160	8	related	relate	VBN
cord-003614-63rzzos3	160	9	IRF7	IRF7	NNP
cord-003614-63rzzos3	160	10	,	,	,
cord-003614-63rzzos3	160	11	an	an	DT
cord-003614-63rzzos3	160	12	important	important	JJ
cord-003614-63rzzos3	160	13	role	role	NN
cord-003614-63rzzos3	160	14	in	in	IN
cord-003614-63rzzos3	160	15	the	the	DT
cord-003614-63rzzos3	160	16	IFN	IFN	NNP
cord-003614-63rzzos3	160	17	-	-	HYPH
cord-003614-63rzzos3	160	18	I	I	NNP
cord-003614-63rzzos3	160	19	signaling	signal	VBG
cord-003614-63rzzos3	160	20	cascade	cascade	NN
cord-003614-63rzzos3	160	21	and	and	CC
cord-003614-63rzzos3	160	22	the	the	DT
cord-003614-63rzzos3	160	23	control	control	NN
cord-003614-63rzzos3	160	24	of	of	IN
cord-003614-63rzzos3	160	25	viral	viral	JJ
cord-003614-63rzzos3	160	26	infections	infection	NNS
cord-003614-63rzzos3	160	27	[	[	-LRB-
cord-003614-63rzzos3	160	28	53	53	CD
cord-003614-63rzzos3	160	29	]	]	-RRB-
cord-003614-63rzzos3	160	30	.	.	.
cord-003614-63rzzos3	161	1	Ysebrant	Ysebrant	NNP
cord-003614-63rzzos3	161	2	de	de	NNP
cord-003614-63rzzos3	161	3	Lendonck	Lendonck	NNP
cord-003614-63rzzos3	161	4	et	et	NNP
cord-003614-63rzzos3	161	5	al	al	NNP
cord-003614-63rzzos3	161	6	.	.	.
cord-003614-63rzzos3	162	1	(	(	-LRB-
cord-003614-63rzzos3	162	2	2014	2014	CD
cord-003614-63rzzos3	162	3	)	)	-RRB-
cord-003614-63rzzos3	162	4	reported	report	VBD
cord-003614-63rzzos3	162	5	that	that	IN
cord-003614-63rzzos3	162	6	IRF3	IRF3	NNP
cord-003614-63rzzos3	162	7	is	be	VBZ
cord-003614-63rzzos3	162	8	constitutively	constitutively	RB
cord-003614-63rzzos3	162	9	expressed	express	VBN
cord-003614-63rzzos3	162	10	in	in	IN
cord-003614-63rzzos3	162	11	most	most	JJS
cord-003614-63rzzos3	162	12	tissues	tissue	NNS
cord-003614-63rzzos3	162	13	and	and	CC
cord-003614-63rzzos3	162	14	cell	cell	NN
cord-003614-63rzzos3	162	15	types	type	NNS
cord-003614-63rzzos3	162	16	[	[	-LRB-
cord-003614-63rzzos3	162	17	54	54	CD
cord-003614-63rzzos3	162	18	]	]	-RRB-
cord-003614-63rzzos3	162	19	.	.	.
cord-003614-63rzzos3	163	1	Similarly	similarly	RB
cord-003614-63rzzos3	163	2	,	,	,
cord-003614-63rzzos3	163	3	in	in	IN
cord-003614-63rzzos3	163	4	the	the	DT
cord-003614-63rzzos3	163	5	present	present	JJ
cord-003614-63rzzos3	163	6	study	study	NN
cord-003614-63rzzos3	163	7	,	,	,
cord-003614-63rzzos3	163	8	IRF3	IRF3	NNP
cord-003614-63rzzos3	163	9	was	be	VBD
cord-003614-63rzzos3	163	10	expressed	express	VBN
cord-003614-63rzzos3	163	11	in	in	IN
cord-003614-63rzzos3	163	12	most	most	JJS
cord-003614-63rzzos3	163	13	cell	cell	NN
cord-003614-63rzzos3	163	14	types	type	NNS
cord-003614-63rzzos3	163	15	present	present	JJ
cord-003614-63rzzos3	163	16	in	in	IN
cord-003614-63rzzos3	163	17	CDV	CDV	NNP
cord-003614-63rzzos3	163	18	-	-	HYPH
cord-003614-63rzzos3	163	19	induced	induce	VBN
cord-003614-63rzzos3	163	20	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	163	21	lesions	lesion	NNS
cord-003614-63rzzos3	163	22	as	as	RB
cord-003614-63rzzos3	163	23	well	well	RB
cord-003614-63rzzos3	163	24	as	as	IN
cord-003614-63rzzos3	163	25	in	in	IN
cord-003614-63rzzos3	163	26	control	control	NN
cord-003614-63rzzos3	163	27	tissue	tissue	NN
cord-003614-63rzzos3	163	28	(	(	-LRB-
cord-003614-63rzzos3	163	29	endothelial	endothelial	JJ
cord-003614-63rzzos3	163	30	cells	cell	NNS
cord-003614-63rzzos3	163	31	,	,	,
cord-003614-63rzzos3	163	32	neurons	neuron	NNS
cord-003614-63rzzos3	163	33	,	,	,
cord-003614-63rzzos3	163	34	glial	glial	JJ
cord-003614-63rzzos3	163	35	cells	cell	NNS
cord-003614-63rzzos3	163	36	and	and	CC
cord-003614-63rzzos3	163	37	perivascular	perivascular	JJ
cord-003614-63rzzos3	163	38	inflammatory	inflammatory	JJ
cord-003614-63rzzos3	163	39	cells	cell	NNS
cord-003614-63rzzos3	163	40	)	)	-RRB-
cord-003614-63rzzos3	163	41	.	.	.
cord-003614-63rzzos3	164	1	This	this	DT
cord-003614-63rzzos3	164	2	strong	strong	JJ
cord-003614-63rzzos3	164	3	constitutive	constitutive	JJ
cord-003614-63rzzos3	164	4	expression	expression	NN
cord-003614-63rzzos3	164	5	of	of	IN
cord-003614-63rzzos3	164	6	IRF3	IRF3	NNP
cord-003614-63rzzos3	164	7	might	may	MD
cord-003614-63rzzos3	164	8	also	also	RB
cord-003614-63rzzos3	164	9	explain	explain	VB
cord-003614-63rzzos3	164	10	that	that	IN
cord-003614-63rzzos3	164	11	the	the	DT
cord-003614-63rzzos3	164	12	present	present	JJ
cord-003614-63rzzos3	164	13	microarray	microarray	NN
cord-003614-63rzzos3	164	14	analysis	analysis	NN
cord-003614-63rzzos3	164	15	and	and	CC
cord-003614-63rzzos3	164	16	immunohistochemical	immunohistochemical	JJ
cord-003614-63rzzos3	164	17	investigation	investigation	NN
cord-003614-63rzzos3	164	18	did	do	VBD
cord-003614-63rzzos3	164	19	not	not	RB
cord-003614-63rzzos3	164	20	detect	detect	VB
cord-003614-63rzzos3	164	21	changes	change	NNS
cord-003614-63rzzos3	164	22	in	in	IN
cord-003614-63rzzos3	164	23	the	the	DT
cord-003614-63rzzos3	164	24	gene	gene	NN
cord-003614-63rzzos3	164	25	or	or	CC
cord-003614-63rzzos3	164	26	protein	protein	NN
cord-003614-63rzzos3	164	27	expression	expression	NN
cord-003614-63rzzos3	164	28	of	of	IN
cord-003614-63rzzos3	164	29	this	this	DT
cord-003614-63rzzos3	164	30	transcription	transcription	NN
cord-003614-63rzzos3	164	31	factor	factor	NN
cord-003614-63rzzos3	164	32	in	in	IN
cord-003614-63rzzos3	164	33	acute	acute	JJ
cord-003614-63rzzos3	164	34	,	,	,
cord-003614-63rzzos3	164	35	subacute	subacute	JJ
cord-003614-63rzzos3	164	36	or	or	CC
cord-003614-63rzzos3	164	37	chronic	chronic	JJ
cord-003614-63rzzos3	164	38	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	164	39	lesions	lesion	NNS
cord-003614-63rzzos3	164	40	.	.	.
cord-003614-63rzzos3	165	1	Nonetheless	nonetheless	RB
cord-003614-63rzzos3	165	2	,	,	,
cord-003614-63rzzos3	165	3	there	there	EX
cord-003614-63rzzos3	165	4	was	be	VBD
cord-003614-63rzzos3	165	5	a	a	DT
cord-003614-63rzzos3	165	6	significant	significant	JJ
cord-003614-63rzzos3	165	7	increase	increase	NN
cord-003614-63rzzos3	165	8	in	in	IN
cord-003614-63rzzos3	165	9	IRF3	IRF3	NNP
cord-003614-63rzzos3	165	10	protein	protein	NN
cord-003614-63rzzos3	165	11	expression	expression	NN
cord-003614-63rzzos3	165	12	in	in	IN
cord-003614-63rzzos3	165	13	CDV	CDV	NNP
cord-003614-63rzzos3	165	14	-	-	HYPH
cord-003614-63rzzos3	165	15	infected	infect	VBN
cord-003614-63rzzos3	165	16	areas	area	NNS
cord-003614-63rzzos3	165	17	lacking	lack	VBG
cord-003614-63rzzos3	165	18	histological	histological	JJ
cord-003614-63rzzos3	165	19	lesions	lesion	NNS
cord-003614-63rzzos3	165	20	(	(	-LRB-
cord-003614-63rzzos3	165	21	group	group	NN
cord-003614-63rzzos3	165	22	2	2	CD
cord-003614-63rzzos3	165	23	)	)	-RRB-
cord-003614-63rzzos3	165	24	compared	compare	VBN
cord-003614-63rzzos3	165	25	to	to	IN
cord-003614-63rzzos3	165	26	controls	control	NNS
cord-003614-63rzzos3	165	27	demonstrating	demonstrate	VBG
cord-003614-63rzzos3	165	28	an	an	DT
cord-003614-63rzzos3	165	29	early	early	JJ
cord-003614-63rzzos3	165	30	activation	activation	NN
cord-003614-63rzzos3	165	31	of	of	IN
cord-003614-63rzzos3	165	32	IFN	IFN	NNP
cord-003614-63rzzos3	165	33	-	-	HYPH
cord-003614-63rzzos3	165	34	I	I	NNP
cord-003614-63rzzos3	165	35	signaling	signal	VBG
cord-003614-63rzzos3	165	36	in	in	IN
cord-003614-63rzzos3	165	37	the	the	DT
cord-003614-63rzzos3	165	38	disease	disease	NN
cord-003614-63rzzos3	165	39	process	process	NN
cord-003614-63rzzos3	165	40	.	.	.
cord-003614-63rzzos3	166	1	IRF3	IRF3	NNP
cord-003614-63rzzos3	166	2	interacts	interact	VBZ
cord-003614-63rzzos3	166	3	with	with	IN
cord-003614-63rzzos3	166	4	other	other	JJ
cord-003614-63rzzos3	166	5	transcription	transcription	NN
cord-003614-63rzzos3	166	6	factors	factor	NNS
cord-003614-63rzzos3	166	7	,	,	,
cord-003614-63rzzos3	166	8	coactivators	coactivator	NNS
cord-003614-63rzzos3	166	9	and	and	CC
cord-003614-63rzzos3	166	10	repressors	repressor	NNS
cord-003614-63rzzos3	166	11	including	include	VBG
cord-003614-63rzzos3	166	12	other	other	JJ
cord-003614-63rzzos3	166	13	IRFs	irfs	NN
cord-003614-63rzzos3	166	14	and	and	CC
cord-003614-63rzzos3	166	15	NF	nf	NN
cord-003614-63rzzos3	166	16	-	-	HYPH
cord-003614-63rzzos3	166	17	κB	κB	NNP
cord-003614-63rzzos3	166	18	and	and	CC
cord-003614-63rzzos3	166	19	thereby	thereby	RB
cord-003614-63rzzos3	166	20	regulates	regulate	VBZ
cord-003614-63rzzos3	166	21	T	t	NN
cord-003614-63rzzos3	166	22	cell	cell	NN
cord-003614-63rzzos3	166	23	differentiation	differentiation	NN
cord-003614-63rzzos3	166	24	into	into	IN
cord-003614-63rzzos3	166	25	Th1	th1	NN
cord-003614-63rzzos3	166	26	,	,	,
cord-003614-63rzzos3	166	27	Th2	Th2	NNP
cord-003614-63rzzos3	166	28	and	and	CC
cord-003614-63rzzos3	166	29	Th17	Th17	NNP
cord-003614-63rzzos3	166	30	cells	cell	NNS
cord-003614-63rzzos3	166	31	as	as	RB
cord-003614-63rzzos3	166	32	well	well	RB
cord-003614-63rzzos3	166	33	as	as	IN
cord-003614-63rzzos3	166	34	induces	induce	VBZ
cord-003614-63rzzos3	166	35	apoptosis	apoptosis	NN
cord-003614-63rzzos3	166	36	during	during	IN
cord-003614-63rzzos3	166	37	viral	viral	JJ
cord-003614-63rzzos3	166	38	infections	infection	NNS
cord-003614-63rzzos3	166	39	[	[	-LRB-
cord-003614-63rzzos3	166	40	54	54	CD
cord-003614-63rzzos3	166	41	]	]	-RRB-
cord-003614-63rzzos3	166	42	.	.	.
cord-003614-63rzzos3	167	1	Thus	thus	RB
cord-003614-63rzzos3	167	2	,	,	,
cord-003614-63rzzos3	167	3	IRF3	IRF3	NNP
cord-003614-63rzzos3	167	4	most	most	RBS
cord-003614-63rzzos3	167	5	likely	likely	RB
cord-003614-63rzzos3	167	6	modulates	modulate	VBZ
cord-003614-63rzzos3	167	7	adaptive	adaptive	JJ
cord-003614-63rzzos3	167	8	immune	immune	JJ
cord-003614-63rzzos3	167	9	responses	response	NNS
cord-003614-63rzzos3	167	10	at	at	IN
cord-003614-63rzzos3	167	11	all	all	DT
cord-003614-63rzzos3	167	12	stages	stage	NNS
cord-003614-63rzzos3	167	13	of	of	IN
cord-003614-63rzzos3	167	14	CDV	CDV	NNP
cord-003614-63rzzos3	167	15	-	-	HYPH
cord-003614-63rzzos3	167	16	induced	induce	VBN
cord-003614-63rzzos3	167	17	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	167	18	lesions	lesion	NNS
cord-003614-63rzzos3	167	19	due	due	JJ
cord-003614-63rzzos3	167	20	to	to	IN
cord-003614-63rzzos3	167	21	its	-PRON-	PRP$
cord-003614-63rzzos3	167	22	action	action	NN
cord-003614-63rzzos3	167	23	as	as	IN
cord-003614-63rzzos3	167	24	a	a	DT
cord-003614-63rzzos3	167	25	signaling	signal	VBG
cord-003614-63rzzos3	167	26	platform	platform	NN
cord-003614-63rzzos3	167	27	,	,	,
cord-003614-63rzzos3	167	28	which	which	WDT
cord-003614-63rzzos3	167	29	IRF3	IRF3	NNP
cord-003614-63rzzos3	167	30	can	can	MD
cord-003614-63rzzos3	167	31	fulfill	fulfill	VB
cord-003614-63rzzos3	167	32	without	without	IN
cord-003614-63rzzos3	167	33	changes	change	NNS
cord-003614-63rzzos3	167	34	in	in	IN
cord-003614-63rzzos3	167	35	expression	expression	NN
cord-003614-63rzzos3	167	36	.	.	.
cord-003614-63rzzos3	168	1	Unlike	unlike	IN
cord-003614-63rzzos3	168	2	IRF3	IRF3	NNP
cord-003614-63rzzos3	168	3	,	,	,
cord-003614-63rzzos3	168	4	IRF7	IRF7	NNP
cord-003614-63rzzos3	168	5	is	be	VBZ
cord-003614-63rzzos3	168	6	reported	report	VBN
cord-003614-63rzzos3	168	7	to	to	TO
cord-003614-63rzzos3	168	8	be	be	VB
cord-003614-63rzzos3	168	9	expressed	express	VBN
cord-003614-63rzzos3	168	10	only	only	RB
cord-003614-63rzzos3	168	11	at	at	IN
cord-003614-63rzzos3	168	12	low	low	JJ
cord-003614-63rzzos3	168	13	levels	level	NNS
cord-003614-63rzzos3	168	14	in	in	IN
cord-003614-63rzzos3	168	15	most	most	JJS
cord-003614-63rzzos3	168	16	cell	cell	NN
cord-003614-63rzzos3	168	17	types	type	NNS
cord-003614-63rzzos3	168	18	and	and	CC
cord-003614-63rzzos3	168	19	has	have	VBZ
cord-003614-63rzzos3	168	20	to	to	TO
cord-003614-63rzzos3	168	21	be	be	VB
cord-003614-63rzzos3	168	22	continuously	continuously	RB
cord-003614-63rzzos3	168	23	produced	produce	VBN
cord-003614-63rzzos3	168	24	due	due	IN
cord-003614-63rzzos3	168	25	to	to	IN
cord-003614-63rzzos3	168	26	its	-PRON-	PRP$
cord-003614-63rzzos3	168	27	short	short	JJ
cord-003614-63rzzos3	168	28	half	half	JJ
cord-003614-63rzzos3	168	29	-	-	HYPH
cord-003614-63rzzos3	168	30	life	life	NN
cord-003614-63rzzos3	168	31	time	time	NN
cord-003614-63rzzos3	168	32	of	of	IN
cord-003614-63rzzos3	168	33	0.5	0.5	CD
cord-003614-63rzzos3	168	34	-	-	SYM
cord-003614-63rzzos3	168	35	1	1	CD
cord-003614-63rzzos3	168	36	h	h	NN
cord-003614-63rzzos3	168	37	[	[	-LRB-
cord-003614-63rzzos3	168	38	55	55	CD
cord-003614-63rzzos3	168	39	,	,	,
cord-003614-63rzzos3	168	40	56	56	CD
cord-003614-63rzzos3	168	41	]	]	-RRB-
cord-003614-63rzzos3	168	42	.	.	.
cord-003614-63rzzos3	169	1	Nevertheless	nevertheless	RB
cord-003614-63rzzos3	169	2	,	,	,
cord-003614-63rzzos3	169	3	IRF7	IRF7	NNP
cord-003614-63rzzos3	169	4	protein	protein	NN
cord-003614-63rzzos3	169	5	was	be	VBD
cord-003614-63rzzos3	169	6	present	present	JJ
cord-003614-63rzzos3	169	7	in	in	IN
cord-003614-63rzzos3	169	8	neurons	neuron	NNS
cord-003614-63rzzos3	169	9	of	of	IN
cord-003614-63rzzos3	169	10	the	the	DT
cord-003614-63rzzos3	169	11	granular	granular	JJ
cord-003614-63rzzos3	169	12	layer	layer	NN
cord-003614-63rzzos3	169	13	and	and	CC
cord-003614-63rzzos3	169	14	individual	individual	JJ
cord-003614-63rzzos3	169	15	glial	glial	JJ
cord-003614-63rzzos3	169	16	cells	cell	NNS
cord-003614-63rzzos3	169	17	,	,	,
cord-003614-63rzzos3	169	18	even	even	RB
cord-003614-63rzzos3	169	19	in	in	IN
cord-003614-63rzzos3	169	20	control	control	NN
cord-003614-63rzzos3	169	21	cerebellum	cerebellum	NN
cord-003614-63rzzos3	169	22	,	,	,
cord-003614-63rzzos3	169	23	showing	show	VBG
cord-003614-63rzzos3	169	24	low	low	JJ
cord-003614-63rzzos3	169	25	constitutive	constitutive	JJ
cord-003614-63rzzos3	169	26	expression	expression	NN
cord-003614-63rzzos3	169	27	of	of	IN
cord-003614-63rzzos3	169	28	this	this	DT
cord-003614-63rzzos3	169	29	transcription	transcription	NN
cord-003614-63rzzos3	169	30	factor	factor	NN
cord-003614-63rzzos3	169	31	in	in	IN
cord-003614-63rzzos3	169	32	the	the	DT
cord-003614-63rzzos3	169	33	canine	canine	JJ
cord-003614-63rzzos3	169	34	CNS	CNS	NNP
cord-003614-63rzzos3	169	35	.	.	.
cord-003614-63rzzos3	170	1	OASL1knockout	OASL1knockout	NNP
cord-003614-63rzzos3	171	1	mice	mice	NNP
cord-003614-63rzzos3	171	2	studies	study	NNS
cord-003614-63rzzos3	171	3	showed	show	VBD
cord-003614-63rzzos3	171	4	that	that	IN
cord-003614-63rzzos3	171	5	OASL1	OASL1	NNP
cord-003614-63rzzos3	171	6	inhibits	inhibit	VBZ
cord-003614-63rzzos3	171	7	IRF7	IRF7	NNP
cord-003614-63rzzos3	171	8	translation	translation	NN
cord-003614-63rzzos3	171	9	and	and	CC
cord-003614-63rzzos3	171	10	thereby	thereby	RB
cord-003614-63rzzos3	171	11	negatively	negatively	RB
cord-003614-63rzzos3	171	12	 	 	_SP
cord-003614-63rzzos3	171	13	The	the	DT
cord-003614-63rzzos3	171	14	present	present	JJ
cord-003614-63rzzos3	171	15	study	study	NN
cord-003614-63rzzos3	171	16	gives	give	VBZ
cord-003614-63rzzos3	171	17	an	an	DT
cord-003614-63rzzos3	171	18	overview	overview	NN
cord-003614-63rzzos3	171	19	of	of	IN
cord-003614-63rzzos3	171	20	the	the	DT
cord-003614-63rzzos3	171	21	protein	protein	NN
cord-003614-63rzzos3	171	22	expression	expression	NN
cord-003614-63rzzos3	171	23	of	of	IN
cord-003614-63rzzos3	171	24	selected	select	VBN
cord-003614-63rzzos3	171	25	IFN	IFN	NNP
cord-003614-63rzzos3	171	26	-	-	HYPH
cord-003614-63rzzos3	171	27	I	I	NNP
cord-003614-63rzzos3	171	28	pathway	pathway	NN
cord-003614-63rzzos3	171	29	members	member	NNS
cord-003614-63rzzos3	171	30	and	and	CC
cord-003614-63rzzos3	171	31	compares	compare	VBZ
cord-003614-63rzzos3	171	32	it	-PRON-	PRP
cord-003614-63rzzos3	171	33	with	with	IN
cord-003614-63rzzos3	171	34	existing	exist	VBG
cord-003614-63rzzos3	171	35	microarray	microarray	NN
cord-003614-63rzzos3	171	36	data	datum	NNS
cord-003614-63rzzos3	171	37	.	.	.
cord-003614-63rzzos3	172	1	Previous	previous	JJ
cord-003614-63rzzos3	172	2	studies	study	NNS
cord-003614-63rzzos3	172	3	often	often	RB
cord-003614-63rzzos3	172	4	investigated	investigate	VBD
cord-003614-63rzzos3	172	5	ISG	ISG	NNP
cord-003614-63rzzos3	172	6	expression	expression	NN
cord-003614-63rzzos3	172	7	in	in	IN
cord-003614-63rzzos3	172	8	cell	cell	NN
cord-003614-63rzzos3	172	9	cultures	culture	NNS
cord-003614-63rzzos3	172	10	,	,	,
cord-003614-63rzzos3	172	11	whereas	whereas	IN
cord-003614-63rzzos3	172	12	studies	study	NNS
cord-003614-63rzzos3	172	13	on	on	IN
cord-003614-63rzzos3	172	14	the	the	DT
cord-003614-63rzzos3	172	15	protein	protein	NN
cord-003614-63rzzos3	172	16	expression	expression	NN
cord-003614-63rzzos3	172	17	of	of	IN
cord-003614-63rzzos3	172	18	ISGs	isg	NNS
cord-003614-63rzzos3	172	19	in	in	IN
cord-003614-63rzzos3	172	20	a	a	DT
cord-003614-63rzzos3	172	21	naturally	naturally	RB
cord-003614-63rzzos3	172	22	occurring	occur	VBG
cord-003614-63rzzos3	172	23	animal	animal	NN
cord-003614-63rzzos3	172	24	disease	disease	NN
cord-003614-63rzzos3	172	25	are	be	VBP
cord-003614-63rzzos3	172	26	rare	rare	JJ
cord-003614-63rzzos3	172	27	[	[	-LRB-
cord-003614-63rzzos3	172	28	48	48	CD
cord-003614-63rzzos3	172	29	]	]	-RRB-
cord-003614-63rzzos3	172	30	[	[	-LRB-
cord-003614-63rzzos3	172	31	49	49	CD
cord-003614-63rzzos3	172	32	]	]	-RRB-
cord-003614-63rzzos3	172	33	[	[	-LRB-
cord-003614-63rzzos3	172	34	50	50	CD
cord-003614-63rzzos3	172	35	]	]	-RRB-
cord-003614-63rzzos3	172	36	[	[	-LRB-
cord-003614-63rzzos3	172	37	51	51	CD
cord-003614-63rzzos3	172	38	]	]	-RRB-
cord-003614-63rzzos3	172	39	[	[	-LRB-
cord-003614-63rzzos3	172	40	52	52	CD
cord-003614-63rzzos3	172	41	]	]	-RRB-
cord-003614-63rzzos3	172	42	.	.	.
cord-003614-63rzzos3	173	1	IRF3	IRF3	NNP
cord-003614-63rzzos3	173	2	plays	play	VBZ
cord-003614-63rzzos3	173	3	,	,	,
cord-003614-63rzzos3	173	4	together	together	RB
cord-003614-63rzzos3	173	5	with	with	IN
cord-003614-63rzzos3	173	6	the	the	DT
cord-003614-63rzzos3	173	7	closely	closely	RB
cord-003614-63rzzos3	173	8	related	relate	VBN
cord-003614-63rzzos3	173	9	IRF7	IRF7	NNP
cord-003614-63rzzos3	173	10	,	,	,
cord-003614-63rzzos3	173	11	an	an	DT
cord-003614-63rzzos3	173	12	important	important	JJ
cord-003614-63rzzos3	173	13	role	role	NN
cord-003614-63rzzos3	173	14	in	in	IN
cord-003614-63rzzos3	173	15	the	the	DT
cord-003614-63rzzos3	173	16	IFN	IFN	NNP
cord-003614-63rzzos3	173	17	-	-	HYPH
cord-003614-63rzzos3	173	18	I	I	NNP
cord-003614-63rzzos3	173	19	signaling	signal	VBG
cord-003614-63rzzos3	173	20	cascade	cascade	NN
cord-003614-63rzzos3	173	21	and	and	CC
cord-003614-63rzzos3	173	22	the	the	DT
cord-003614-63rzzos3	173	23	control	control	NN
cord-003614-63rzzos3	173	24	of	of	IN
cord-003614-63rzzos3	173	25	viral	viral	JJ
cord-003614-63rzzos3	173	26	infections	infection	NNS
cord-003614-63rzzos3	173	27	[	[	-LRB-
cord-003614-63rzzos3	173	28	53	53	CD
cord-003614-63rzzos3	173	29	]	]	-RRB-
cord-003614-63rzzos3	173	30	.	.	.
cord-003614-63rzzos3	174	1	Ysebrant	Ysebrant	NNP
cord-003614-63rzzos3	174	2	de	de	NNP
cord-003614-63rzzos3	174	3	Lendonck	Lendonck	NNP
cord-003614-63rzzos3	174	4	et	et	NNP
cord-003614-63rzzos3	174	5	al	al	NNP
cord-003614-63rzzos3	174	6	.	.	.
cord-003614-63rzzos3	175	1	(	(	-LRB-
cord-003614-63rzzos3	175	2	2014	2014	CD
cord-003614-63rzzos3	175	3	)	)	-RRB-
cord-003614-63rzzos3	175	4	reported	report	VBD
cord-003614-63rzzos3	175	5	that	that	IN
cord-003614-63rzzos3	175	6	IRF3	IRF3	NNP
cord-003614-63rzzos3	175	7	is	be	VBZ
cord-003614-63rzzos3	175	8	constitutively	constitutively	RB
cord-003614-63rzzos3	175	9	expressed	express	VBN
cord-003614-63rzzos3	175	10	in	in	IN
cord-003614-63rzzos3	175	11	most	most	JJS
cord-003614-63rzzos3	175	12	tissues	tissue	NNS
cord-003614-63rzzos3	175	13	and	and	CC
cord-003614-63rzzos3	175	14	cell	cell	NN
cord-003614-63rzzos3	175	15	types	type	NNS
cord-003614-63rzzos3	175	16	[	[	-LRB-
cord-003614-63rzzos3	175	17	54	54	CD
cord-003614-63rzzos3	175	18	]	]	-RRB-
cord-003614-63rzzos3	175	19	.	.	.
cord-003614-63rzzos3	176	1	Similarly	similarly	RB
cord-003614-63rzzos3	176	2	,	,	,
cord-003614-63rzzos3	176	3	in	in	IN
cord-003614-63rzzos3	176	4	the	the	DT
cord-003614-63rzzos3	176	5	present	present	JJ
cord-003614-63rzzos3	176	6	study	study	NN
cord-003614-63rzzos3	176	7	,	,	,
cord-003614-63rzzos3	176	8	IRF3	IRF3	NNP
cord-003614-63rzzos3	176	9	was	be	VBD
cord-003614-63rzzos3	176	10	expressed	express	VBN
cord-003614-63rzzos3	176	11	in	in	IN
cord-003614-63rzzos3	176	12	most	most	JJS
cord-003614-63rzzos3	176	13	cell	cell	NN
cord-003614-63rzzos3	176	14	types	type	NNS
cord-003614-63rzzos3	176	15	present	present	JJ
cord-003614-63rzzos3	176	16	in	in	IN
cord-003614-63rzzos3	176	17	CDV	CDV	NNP
cord-003614-63rzzos3	176	18	-	-	HYPH
cord-003614-63rzzos3	176	19	induced	induce	VBN
cord-003614-63rzzos3	176	20	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	176	21	lesions	lesion	NNS
cord-003614-63rzzos3	176	22	as	as	RB
cord-003614-63rzzos3	176	23	well	well	RB
cord-003614-63rzzos3	176	24	as	as	IN
cord-003614-63rzzos3	176	25	in	in	IN
cord-003614-63rzzos3	176	26	control	control	NN
cord-003614-63rzzos3	176	27	tissue	tissue	NN
cord-003614-63rzzos3	176	28	(	(	-LRB-
cord-003614-63rzzos3	176	29	endothelial	endothelial	JJ
cord-003614-63rzzos3	176	30	cells	cell	NNS
cord-003614-63rzzos3	176	31	,	,	,
cord-003614-63rzzos3	176	32	neurons	neuron	NNS
cord-003614-63rzzos3	176	33	,	,	,
cord-003614-63rzzos3	176	34	glial	glial	JJ
cord-003614-63rzzos3	176	35	cells	cell	NNS
cord-003614-63rzzos3	176	36	and	and	CC
cord-003614-63rzzos3	176	37	perivascular	perivascular	JJ
cord-003614-63rzzos3	176	38	inflammatory	inflammatory	JJ
cord-003614-63rzzos3	176	39	cells	cell	NNS
cord-003614-63rzzos3	176	40	)	)	-RRB-
cord-003614-63rzzos3	176	41	.	.	.
cord-003614-63rzzos3	177	1	This	this	DT
cord-003614-63rzzos3	177	2	strong	strong	JJ
cord-003614-63rzzos3	177	3	constitutive	constitutive	JJ
cord-003614-63rzzos3	177	4	expression	expression	NN
cord-003614-63rzzos3	177	5	of	of	IN
cord-003614-63rzzos3	177	6	IRF3	IRF3	NNP
cord-003614-63rzzos3	177	7	might	may	MD
cord-003614-63rzzos3	177	8	also	also	RB
cord-003614-63rzzos3	177	9	explain	explain	VB
cord-003614-63rzzos3	177	10	that	that	IN
cord-003614-63rzzos3	177	11	the	the	DT
cord-003614-63rzzos3	177	12	present	present	JJ
cord-003614-63rzzos3	177	13	microarray	microarray	NN
cord-003614-63rzzos3	177	14	analysis	analysis	NN
cord-003614-63rzzos3	177	15	and	and	CC
cord-003614-63rzzos3	177	16	immunohistochemical	immunohistochemical	JJ
cord-003614-63rzzos3	177	17	investigation	investigation	NN
cord-003614-63rzzos3	177	18	did	do	VBD
cord-003614-63rzzos3	177	19	not	not	RB
cord-003614-63rzzos3	177	20	detect	detect	VB
cord-003614-63rzzos3	177	21	changes	change	NNS
cord-003614-63rzzos3	177	22	in	in	IN
cord-003614-63rzzos3	177	23	the	the	DT
cord-003614-63rzzos3	177	24	gene	gene	NN
cord-003614-63rzzos3	177	25	or	or	CC
cord-003614-63rzzos3	177	26	protein	protein	NN
cord-003614-63rzzos3	177	27	expression	expression	NN
cord-003614-63rzzos3	177	28	of	of	IN
cord-003614-63rzzos3	177	29	this	this	DT
cord-003614-63rzzos3	177	30	transcription	transcription	NN
cord-003614-63rzzos3	177	31	factor	factor	NN
cord-003614-63rzzos3	177	32	in	in	IN
cord-003614-63rzzos3	177	33	acute	acute	JJ
cord-003614-63rzzos3	177	34	,	,	,
cord-003614-63rzzos3	177	35	subacute	subacute	JJ
cord-003614-63rzzos3	177	36	or	or	CC
cord-003614-63rzzos3	177	37	chronic	chronic	JJ
cord-003614-63rzzos3	177	38	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	177	39	lesions	lesion	NNS
cord-003614-63rzzos3	177	40	.	.	.
cord-003614-63rzzos3	178	1	Nonetheless	nonetheless	RB
cord-003614-63rzzos3	178	2	,	,	,
cord-003614-63rzzos3	178	3	there	there	EX
cord-003614-63rzzos3	178	4	was	be	VBD
cord-003614-63rzzos3	178	5	a	a	DT
cord-003614-63rzzos3	178	6	significant	significant	JJ
cord-003614-63rzzos3	178	7	increase	increase	NN
cord-003614-63rzzos3	178	8	in	in	IN
cord-003614-63rzzos3	178	9	IRF3	IRF3	NNP
cord-003614-63rzzos3	178	10	protein	protein	NN
cord-003614-63rzzos3	178	11	expression	expression	NN
cord-003614-63rzzos3	178	12	in	in	IN
cord-003614-63rzzos3	178	13	CDV	CDV	NNP
cord-003614-63rzzos3	178	14	-	-	HYPH
cord-003614-63rzzos3	178	15	infected	infect	VBN
cord-003614-63rzzos3	178	16	areas	area	NNS
cord-003614-63rzzos3	178	17	lacking	lack	VBG
cord-003614-63rzzos3	178	18	histological	histological	JJ
cord-003614-63rzzos3	178	19	lesions	lesion	NNS
cord-003614-63rzzos3	178	20	(	(	-LRB-
cord-003614-63rzzos3	178	21	group	group	NN
cord-003614-63rzzos3	178	22	2	2	CD
cord-003614-63rzzos3	178	23	)	)	-RRB-
cord-003614-63rzzos3	178	24	compared	compare	VBN
cord-003614-63rzzos3	178	25	to	to	IN
cord-003614-63rzzos3	178	26	controls	control	NNS
cord-003614-63rzzos3	178	27	demonstrating	demonstrate	VBG
cord-003614-63rzzos3	178	28	an	an	DT
cord-003614-63rzzos3	178	29	early	early	JJ
cord-003614-63rzzos3	178	30	activation	activation	NN
cord-003614-63rzzos3	178	31	of	of	IN
cord-003614-63rzzos3	178	32	IFN	IFN	NNP
cord-003614-63rzzos3	178	33	-	-	HYPH
cord-003614-63rzzos3	178	34	I	I	NNP
cord-003614-63rzzos3	178	35	signaling	signal	VBG
cord-003614-63rzzos3	178	36	in	in	IN
cord-003614-63rzzos3	178	37	the	the	DT
cord-003614-63rzzos3	178	38	disease	disease	NN
cord-003614-63rzzos3	178	39	process	process	NN
cord-003614-63rzzos3	178	40	.	.	.
cord-003614-63rzzos3	179	1	IRF3	IRF3	NNP
cord-003614-63rzzos3	179	2	interacts	interact	VBZ
cord-003614-63rzzos3	179	3	with	with	IN
cord-003614-63rzzos3	179	4	other	other	JJ
cord-003614-63rzzos3	179	5	transcription	transcription	NN
cord-003614-63rzzos3	179	6	factors	factor	NNS
cord-003614-63rzzos3	179	7	,	,	,
cord-003614-63rzzos3	179	8	coactivators	coactivator	NNS
cord-003614-63rzzos3	179	9	and	and	CC
cord-003614-63rzzos3	179	10	repressors	repressor	NNS
cord-003614-63rzzos3	179	11	including	include	VBG
cord-003614-63rzzos3	179	12	other	other	JJ
cord-003614-63rzzos3	179	13	IRFs	irfs	NN
cord-003614-63rzzos3	179	14	and	and	CC
cord-003614-63rzzos3	179	15	NF	nf	NN
cord-003614-63rzzos3	179	16	-	-	HYPH
cord-003614-63rzzos3	179	17	κB	κB	NNP
cord-003614-63rzzos3	179	18	and	and	CC
cord-003614-63rzzos3	179	19	thereby	thereby	RB
cord-003614-63rzzos3	179	20	regulates	regulate	VBZ
cord-003614-63rzzos3	179	21	T	t	NN
cord-003614-63rzzos3	179	22	cell	cell	NN
cord-003614-63rzzos3	179	23	differentiation	differentiation	NN
cord-003614-63rzzos3	179	24	into	into	IN
cord-003614-63rzzos3	179	25	Th1	th1	NN
cord-003614-63rzzos3	179	26	,	,	,
cord-003614-63rzzos3	179	27	Th2	Th2	NNP
cord-003614-63rzzos3	179	28	and	and	CC
cord-003614-63rzzos3	179	29	Th17	Th17	NNP
cord-003614-63rzzos3	179	30	cells	cell	NNS
cord-003614-63rzzos3	179	31	as	as	RB
cord-003614-63rzzos3	179	32	well	well	RB
cord-003614-63rzzos3	179	33	as	as	IN
cord-003614-63rzzos3	179	34	induces	induce	VBZ
cord-003614-63rzzos3	179	35	apoptosis	apoptosis	NN
cord-003614-63rzzos3	179	36	during	during	IN
cord-003614-63rzzos3	179	37	viral	viral	JJ
cord-003614-63rzzos3	179	38	infections	infection	NNS
cord-003614-63rzzos3	179	39	[	[	-LRB-
cord-003614-63rzzos3	179	40	54	54	CD
cord-003614-63rzzos3	179	41	]	]	-RRB-
cord-003614-63rzzos3	179	42	.	.	.
cord-003614-63rzzos3	180	1	Thus	thus	RB
cord-003614-63rzzos3	180	2	,	,	,
cord-003614-63rzzos3	180	3	IRF3	IRF3	NNP
cord-003614-63rzzos3	180	4	most	most	RBS
cord-003614-63rzzos3	180	5	likely	likely	RB
cord-003614-63rzzos3	180	6	modulates	modulate	VBZ
cord-003614-63rzzos3	180	7	adaptive	adaptive	JJ
cord-003614-63rzzos3	180	8	immune	immune	JJ
cord-003614-63rzzos3	180	9	responses	response	NNS
cord-003614-63rzzos3	180	10	at	at	IN
cord-003614-63rzzos3	180	11	all	all	DT
cord-003614-63rzzos3	180	12	stages	stage	NNS
cord-003614-63rzzos3	180	13	of	of	IN
cord-003614-63rzzos3	180	14	CDV	CDV	NNP
cord-003614-63rzzos3	180	15	-	-	HYPH
cord-003614-63rzzos3	180	16	induced	induce	VBN
cord-003614-63rzzos3	180	17	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	180	18	lesions	lesion	NNS
cord-003614-63rzzos3	180	19	due	due	JJ
cord-003614-63rzzos3	180	20	to	to	IN
cord-003614-63rzzos3	180	21	its	-PRON-	PRP$
cord-003614-63rzzos3	180	22	action	action	NN
cord-003614-63rzzos3	180	23	as	as	IN
cord-003614-63rzzos3	180	24	a	a	DT
cord-003614-63rzzos3	180	25	signaling	signal	VBG
cord-003614-63rzzos3	180	26	platform	platform	NN
cord-003614-63rzzos3	180	27	,	,	,
cord-003614-63rzzos3	180	28	which	which	WDT
cord-003614-63rzzos3	180	29	IRF3	IRF3	NNP
cord-003614-63rzzos3	180	30	can	can	MD
cord-003614-63rzzos3	180	31	fulfill	fulfill	VB
cord-003614-63rzzos3	180	32	without	without	IN
cord-003614-63rzzos3	180	33	changes	change	NNS
cord-003614-63rzzos3	180	34	in	in	IN
cord-003614-63rzzos3	180	35	expression	expression	NN
cord-003614-63rzzos3	180	36	.	.	.
cord-003614-63rzzos3	181	1	Unlike	unlike	IN
cord-003614-63rzzos3	181	2	IRF3	IRF3	NNP
cord-003614-63rzzos3	181	3	,	,	,
cord-003614-63rzzos3	181	4	IRF7	IRF7	NNP
cord-003614-63rzzos3	181	5	is	be	VBZ
cord-003614-63rzzos3	181	6	reported	report	VBN
cord-003614-63rzzos3	181	7	to	to	TO
cord-003614-63rzzos3	181	8	be	be	VB
cord-003614-63rzzos3	181	9	expressed	express	VBN
cord-003614-63rzzos3	181	10	only	only	RB
cord-003614-63rzzos3	181	11	at	at	IN
cord-003614-63rzzos3	181	12	low	low	JJ
cord-003614-63rzzos3	181	13	levels	level	NNS
cord-003614-63rzzos3	181	14	in	in	IN
cord-003614-63rzzos3	181	15	most	most	JJS
cord-003614-63rzzos3	181	16	cell	cell	NN
cord-003614-63rzzos3	181	17	types	type	NNS
cord-003614-63rzzos3	181	18	and	and	CC
cord-003614-63rzzos3	181	19	has	have	VBZ
cord-003614-63rzzos3	181	20	to	to	TO
cord-003614-63rzzos3	181	21	be	be	VB
cord-003614-63rzzos3	181	22	continuously	continuously	RB
cord-003614-63rzzos3	181	23	produced	produce	VBN
cord-003614-63rzzos3	181	24	due	due	IN
cord-003614-63rzzos3	181	25	to	to	IN
cord-003614-63rzzos3	181	26	its	-PRON-	PRP$
cord-003614-63rzzos3	181	27	short	short	JJ
cord-003614-63rzzos3	181	28	half	half	JJ
cord-003614-63rzzos3	181	29	-	-	HYPH
cord-003614-63rzzos3	181	30	life	life	NN
cord-003614-63rzzos3	181	31	time	time	NN
cord-003614-63rzzos3	181	32	of	of	IN
cord-003614-63rzzos3	181	33	0.5	0.5	CD
cord-003614-63rzzos3	181	34	-	-	SYM
cord-003614-63rzzos3	181	35	1	1	CD
cord-003614-63rzzos3	181	36	h	h	NN
cord-003614-63rzzos3	181	37	[	[	-LRB-
cord-003614-63rzzos3	181	38	55	55	CD
cord-003614-63rzzos3	181	39	,	,	,
cord-003614-63rzzos3	181	40	56	56	CD
cord-003614-63rzzos3	181	41	]	]	-RRB-
cord-003614-63rzzos3	181	42	.	.	.
cord-003614-63rzzos3	182	1	Nevertheless	nevertheless	RB
cord-003614-63rzzos3	182	2	,	,	,
cord-003614-63rzzos3	182	3	IRF7	IRF7	NNP
cord-003614-63rzzos3	182	4	protein	protein	NN
cord-003614-63rzzos3	182	5	was	be	VBD
cord-003614-63rzzos3	182	6	present	present	JJ
cord-003614-63rzzos3	182	7	in	in	IN
cord-003614-63rzzos3	182	8	neurons	neuron	NNS
cord-003614-63rzzos3	182	9	of	of	IN
cord-003614-63rzzos3	182	10	the	the	DT
cord-003614-63rzzos3	182	11	granular	granular	JJ
cord-003614-63rzzos3	182	12	layer	layer	NN
cord-003614-63rzzos3	182	13	and	and	CC
cord-003614-63rzzos3	182	14	individual	individual	JJ
cord-003614-63rzzos3	182	15	glial	glial	JJ
cord-003614-63rzzos3	182	16	cells	cell	NNS
cord-003614-63rzzos3	182	17	,	,	,
cord-003614-63rzzos3	182	18	even	even	RB
cord-003614-63rzzos3	182	19	in	in	IN
cord-003614-63rzzos3	182	20	control	control	NN
cord-003614-63rzzos3	182	21	cerebellum	cerebellum	NN
cord-003614-63rzzos3	182	22	,	,	,
cord-003614-63rzzos3	182	23	showing	show	VBG
cord-003614-63rzzos3	182	24	low	low	JJ
cord-003614-63rzzos3	182	25	constitutive	constitutive	JJ
cord-003614-63rzzos3	182	26	expression	expression	NN
cord-003614-63rzzos3	182	27	of	of	IN
cord-003614-63rzzos3	182	28	this	this	DT
cord-003614-63rzzos3	182	29	transcription	transcription	NN
cord-003614-63rzzos3	182	30	factor	factor	NN
cord-003614-63rzzos3	182	31	in	in	IN
cord-003614-63rzzos3	182	32	the	the	DT
cord-003614-63rzzos3	182	33	canine	canine	JJ
cord-003614-63rzzos3	182	34	CNS	CNS	NNP
cord-003614-63rzzos3	182	35	.	.	.
cord-003614-63rzzos3	183	1	OASL1-knockout	oasl1-knockout	JJ
cord-003614-63rzzos3	183	2	mice	mouse	NNS
cord-003614-63rzzos3	183	3	studies	study	NNS
cord-003614-63rzzos3	183	4	showed	show	VBD
cord-003614-63rzzos3	183	5	that	that	IN
cord-003614-63rzzos3	183	6	OASL1	OASL1	NNP
cord-003614-63rzzos3	183	7	inhibits	inhibit	VBZ
cord-003614-63rzzos3	183	8	IRF7	IRF7	NNP
cord-003614-63rzzos3	183	9	translation	translation	NN
cord-003614-63rzzos3	183	10	and	and	CC
cord-003614-63rzzos3	183	11	thereby	thereby	RB
cord-003614-63rzzos3	183	12	negatively	negatively	RB
cord-003614-63rzzos3	183	13	regulates	regulate	VBZ
cord-003614-63rzzos3	183	14	IFN	IFN	NNP
cord-003614-63rzzos3	183	15	-	-	HYPH
cord-003614-63rzzos3	183	16	I	-PRON-	PRP
cord-003614-63rzzos3	183	17	production	production	NN
cord-003614-63rzzos3	183	18	during	during	IN
cord-003614-63rzzos3	183	19	acute	acute	JJ
cord-003614-63rzzos3	183	20	and	and	CC
cord-003614-63rzzos3	183	21	chronic	chronic	JJ
cord-003614-63rzzos3	183	22	viral	viral	JJ
cord-003614-63rzzos3	183	23	infections	infection	NNS
cord-003614-63rzzos3	183	24	[	[	-LRB-
cord-003614-63rzzos3	183	25	57	57	CD
cord-003614-63rzzos3	183	26	,	,	,
cord-003614-63rzzos3	183	27	58	58	CD
cord-003614-63rzzos3	183	28	]	]	-RRB-
cord-003614-63rzzos3	183	29	.	.	.
cord-003614-63rzzos3	184	1	The	the	DT
cord-003614-63rzzos3	184	2	present	present	JJ
cord-003614-63rzzos3	184	3	study	study	NN
cord-003614-63rzzos3	184	4	detected	detect	VBD
cord-003614-63rzzos3	184	5	a	a	DT
cord-003614-63rzzos3	184	6	strong	strong	JJ
cord-003614-63rzzos3	184	7	increase	increase	NN
cord-003614-63rzzos3	184	8	in	in	IN
cord-003614-63rzzos3	184	9	OASL1	oasl1	NN
cord-003614-63rzzos3	185	1	mRNA	mRNA	NNP
cord-003614-63rzzos3	185	2	transcripts	transcript	NNS
cord-003614-63rzzos3	185	3	in	in	IN
cord-003614-63rzzos3	185	4	acute	acute	JJ
cord-003614-63rzzos3	185	5	,	,	,
cord-003614-63rzzos3	185	6	subacute	subacute	JJ
cord-003614-63rzzos3	185	7	and	and	CC
cord-003614-63rzzos3	185	8	chronic	chronic	JJ
cord-003614-63rzzos3	185	9	lesions	lesion	NNS
cord-003614-63rzzos3	185	10	,	,	,
cord-003614-63rzzos3	185	11	which	which	WDT
cord-003614-63rzzos3	185	12	might	may	MD
cord-003614-63rzzos3	185	13	affect	affect	VB
cord-003614-63rzzos3	185	14	IRF7	IRF7	NNP
cord-003614-63rzzos3	185	15	expression	expression	NN
cord-003614-63rzzos3	185	16	.	.	.
cord-003614-63rzzos3	186	1	Nonetheless	nonetheless	RB
cord-003614-63rzzos3	186	2	,	,	,
cord-003614-63rzzos3	186	3	there	there	EX
cord-003614-63rzzos3	186	4	was	be	VBD
cord-003614-63rzzos3	186	5	a	a	DT
cord-003614-63rzzos3	186	6	strong	strong	JJ
cord-003614-63rzzos3	186	7	up	up	NN
cord-003614-63rzzos3	186	8	-	-	HYPH
cord-003614-63rzzos3	186	9	regulation	regulation	NN
cord-003614-63rzzos3	186	10	in	in	IN
cord-003614-63rzzos3	186	11	IRF7	IRF7	NNP
cord-003614-63rzzos3	186	12	gene	gene	NN
cord-003614-63rzzos3	186	13	and	and	CC
cord-003614-63rzzos3	186	14	protein	protein	NN
cord-003614-63rzzos3	186	15	expression	expression	NN
cord-003614-63rzzos3	186	16	in	in	IN
cord-003614-63rzzos3	186	17	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	186	18	lesions	lesion	NNS
cord-003614-63rzzos3	186	19	,	,	,
cord-003614-63rzzos3	186	20	which	which	WDT
cord-003614-63rzzos3	186	21	was	be	VBD
cord-003614-63rzzos3	186	22	most	most	RBS
cord-003614-63rzzos3	186	23	pronounced	pronounce	VBN
cord-003614-63rzzos3	186	24	at	at	IN
cord-003614-63rzzos3	186	25	later	later	JJ
cord-003614-63rzzos3	186	26	stages	stage	NNS
cord-003614-63rzzos3	186	27	of	of	IN
cord-003614-63rzzos3	186	28	CDV	CDV	NNP
cord-003614-63rzzos3	186	29	-	-	HYPH
cord-003614-63rzzos3	186	30	induced	induce	VBN
cord-003614-63rzzos3	186	31	leukoencephalitis	leukoencephalitis	NNP
cord-003614-63rzzos3	186	32	.	.	.
cord-003614-63rzzos3	187	1	This	this	DT
cord-003614-63rzzos3	187	2	continuous	continuous	JJ
cord-003614-63rzzos3	187	3	increase	increase	NN
cord-003614-63rzzos3	187	4	in	in	IN
cord-003614-63rzzos3	187	5	IRF7	IRF7	NNP
cord-003614-63rzzos3	187	6	expression	expression	NN
cord-003614-63rzzos3	187	7	is	be	VBZ
cord-003614-63rzzos3	187	8	probably	probably	RB
cord-003614-63rzzos3	187	9	caused	cause	VBN
cord-003614-63rzzos3	187	10	by	by	IN
cord-003614-63rzzos3	187	11	the	the	DT
cord-003614-63rzzos3	187	12	positive	positive	JJ
cord-003614-63rzzos3	187	13	feedback	feedback	NN
cord-003614-63rzzos3	187	14	mechanism	mechanism	NN
cord-003614-63rzzos3	187	15	of	of	IN
cord-003614-63rzzos3	187	16	IRF7	IRF7	NNP
cord-003614-63rzzos3	187	17	and	and	CC
cord-003614-63rzzos3	187	18	indicates	indicate	VBZ
cord-003614-63rzzos3	187	19	that	that	IN
cord-003614-63rzzos3	187	20	the	the	DT
cord-003614-63rzzos3	187	21	IFN	IFN	NNP
cord-003614-63rzzos3	187	22	-	-	HYPH
cord-003614-63rzzos3	187	23	I	I	NNP
cord-003614-63rzzos3	187	24	signaling	signal	VBG
cord-003614-63rzzos3	187	25	pathway	pathway	NN
cord-003614-63rzzos3	187	26	contributes	contribute	VBZ
cord-003614-63rzzos3	187	27	to	to	IN
cord-003614-63rzzos3	187	28	lesion	lesion	NN
cord-003614-63rzzos3	187	29	progression	progression	NN
cord-003614-63rzzos3	187	30	[	[	-LRB-
cord-003614-63rzzos3	187	31	56	56	CD
cord-003614-63rzzos3	187	32	,	,	,
cord-003614-63rzzos3	187	33	[	[	-LRB-
cord-003614-63rzzos3	187	34	59	59	CD
cord-003614-63rzzos3	187	35	]	]	-RRB-
cord-003614-63rzzos3	187	36	[	[	-LRB-
cord-003614-63rzzos3	187	37	60	60	CD
cord-003614-63rzzos3	187	38	]	]	-RRB-
cord-003614-63rzzos3	187	39	[	[	-LRB-
cord-003614-63rzzos3	187	40	61	61	CD
cord-003614-63rzzos3	187	41	]	]	-RRB-
cord-003614-63rzzos3	187	42	.	.	.
cord-003614-63rzzos3	188	1	STAT1	STAT1	NNP
cord-003614-63rzzos3	188	2	proteins	protein	NNS
cord-003614-63rzzos3	188	3	can	can	MD
cord-003614-63rzzos3	188	4	form	form	VB
cord-003614-63rzzos3	188	5	STAT1	stat1	NN
cord-003614-63rzzos3	188	6	/	/	SYM
cord-003614-63rzzos3	188	7	STAT2	STAT2	NNS
cord-003614-63rzzos3	188	8	heterodimers	heterodimer	NNS
cord-003614-63rzzos3	188	9	and	and	CC
cord-003614-63rzzos3	188	10	STAT1	stat1	VB
cord-003614-63rzzos3	188	11	/	/	SYM
cord-003614-63rzzos3	188	12	STAT1	stat1	VB
cord-003614-63rzzos3	188	13	homodimers	homodimer	NNS
cord-003614-63rzzos3	188	14	to	to	TO
cord-003614-63rzzos3	188	15	induce	induce	VB
cord-003614-63rzzos3	188	16	transcription	transcription	NN
cord-003614-63rzzos3	188	17	of	of	IN
cord-003614-63rzzos3	188	18	ISGs	isg	NNS
cord-003614-63rzzos3	188	19	and	and	CC
cord-003614-63rzzos3	188	20	pro	pro	JJ
cord-003614-63rzzos3	188	21	-	-	JJ
cord-003614-63rzzos3	188	22	inflammatory	inflammatory	JJ
cord-003614-63rzzos3	188	23	cytokines	cytokine	NNS
cord-003614-63rzzos3	188	24	after	after	IN
cord-003614-63rzzos3	188	25	IFN	IFN	NNP
cord-003614-63rzzos3	188	26	-	-	HYPH
cord-003614-63rzzos3	188	27	I	I	NNP
cord-003614-63rzzos3	188	28	and	and	CC
cord-003614-63rzzos3	188	29	IFNγ	IFNγ	VBZ
cord-003614-63rzzos3	188	30	stimulation	stimulation	NN
cord-003614-63rzzos3	188	31	,	,	,
cord-003614-63rzzos3	188	32	respectively	respectively	RB
cord-003614-63rzzos3	188	33	[	[	-LRB-
cord-003614-63rzzos3	188	34	40	40	CD
cord-003614-63rzzos3	188	35	]	]	-RRB-
cord-003614-63rzzos3	188	36	.	.	.
cord-003614-63rzzos3	189	1	Svitek	Svitek	NNP
cord-003614-63rzzos3	189	2	et	et	NNP
cord-003614-63rzzos3	189	3	al	al	NNP
cord-003614-63rzzos3	189	4	.	.	.
cord-003614-63rzzos3	190	1	(	(	-LRB-
cord-003614-63rzzos3	190	2	2014	2014	CD
cord-003614-63rzzos3	190	3	)	)	-RRB-
cord-003614-63rzzos3	190	4	demonstrated	demonstrate	VBD
cord-003614-63rzzos3	190	5	that	that	IN
cord-003614-63rzzos3	190	6	CDV	CDV	NNP
cord-003614-63rzzos3	190	7	has	have	VBZ
cord-003614-63rzzos3	190	8	to	to	TO
cord-003614-63rzzos3	190	9	block	block	VB
cord-003614-63rzzos3	190	10	STAT2	STAT2	NNS
cord-003614-63rzzos3	190	11	signaling	signal	VBG
cord-003614-63rzzos3	190	12	for	for	IN
cord-003614-63rzzos3	190	13	immune	immune	JJ
cord-003614-63rzzos3	190	14	evasion	evasion	NN
cord-003614-63rzzos3	190	15	in	in	IN
cord-003614-63rzzos3	190	16	ferrets	ferret	NNS
cord-003614-63rzzos3	190	17	,	,	,
cord-003614-63rzzos3	190	18	whereas	whereas	IN
cord-003614-63rzzos3	190	19	inhibition	inhibition	NN
cord-003614-63rzzos3	190	20	of	of	IN
cord-003614-63rzzos3	190	21	STAT1	stat1	NN
cord-003614-63rzzos3	190	22	does	do	VBZ
cord-003614-63rzzos3	190	23	not	not	RB
cord-003614-63rzzos3	190	24	contribute	contribute	VB
cord-003614-63rzzos3	190	25	to	to	IN
cord-003614-63rzzos3	190	26	CDV	CDV	NNP
cord-003614-63rzzos3	190	27	virulence	virulence	NN
cord-003614-63rzzos3	190	28	[	[	-LRB-
cord-003614-63rzzos3	190	29	45	45	CD
cord-003614-63rzzos3	190	30	]	]	-RRB-
cord-003614-63rzzos3	190	31	.	.	.
cord-003614-63rzzos3	191	1	The	the	DT
cord-003614-63rzzos3	191	2	present	present	JJ
cord-003614-63rzzos3	191	3	study	study	NN
cord-003614-63rzzos3	191	4	demonstrated	demonstrate	VBD
cord-003614-63rzzos3	191	5	a	a	DT
cord-003614-63rzzos3	191	6	strong	strong	JJ
cord-003614-63rzzos3	191	7	increase	increase	NN
cord-003614-63rzzos3	191	8	in	in	IN
cord-003614-63rzzos3	191	9	STAT1	stat1	NN
cord-003614-63rzzos3	192	1	mRNA	mRNA	NNP
cord-003614-63rzzos3	192	2	transcripts	transcript	NNS
cord-003614-63rzzos3	192	3	and	and	CC
cord-003614-63rzzos3	192	4	proteins	protein	NNS
cord-003614-63rzzos3	192	5	in	in	IN
cord-003614-63rzzos3	192	6	the	the	DT
cord-003614-63rzzos3	192	7	CDV	CDV	NNP
cord-003614-63rzzos3	192	8	-	-	HYPH
cord-003614-63rzzos3	192	9	infected	infect	VBN
cord-003614-63rzzos3	192	10	cerebellum	cerebellum	NN
cord-003614-63rzzos3	193	1	(	(	-LRB-
cord-003614-63rzzos3	193	2	groups	group	NNS
cord-003614-63rzzos3	193	3	2	2	CD
cord-003614-63rzzos3	193	4	-	-	SYM
cord-003614-63rzzos3	193	5	5	5	CD
cord-003614-63rzzos3	193	6	)	)	-RRB-
cord-003614-63rzzos3	193	7	,	,	,
cord-003614-63rzzos3	193	8	whereas	whereas	IN
cord-003614-63rzzos3	193	9	control	control	NN
cord-003614-63rzzos3	193	10	animals	animal	NNS
cord-003614-63rzzos3	193	11	expressed	express	VBD
cord-003614-63rzzos3	193	12	only	only	RB
cord-003614-63rzzos3	193	13	minimal	minimal	JJ
cord-003614-63rzzos3	193	14	amounts	amount	NNS
cord-003614-63rzzos3	193	15	of	of	IN
cord-003614-63rzzos3	193	16	STAT1	stat1	NN
cord-003614-63rzzos3	193	17	.	.	.
cord-003614-63rzzos3	194	1	STAT2	STAT2	NNS
cord-003614-63rzzos3	194	2	proteins	protein	NNS
cord-003614-63rzzos3	194	3	were	be	VBD
cord-003614-63rzzos3	194	4	constitutively	constitutively	RB
cord-003614-63rzzos3	194	5	expressed	express	VBN
cord-003614-63rzzos3	194	6	in	in	IN
cord-003614-63rzzos3	194	7	CDV	CDV	NNP
cord-003614-63rzzos3	194	8	-	-	HYPH
cord-003614-63rzzos3	194	9	infected	infect	VBN
cord-003614-63rzzos3	194	10	and	and	CC
cord-003614-63rzzos3	194	11	control	control	NN
cord-003614-63rzzos3	194	12	tissue	tissue	NN
cord-003614-63rzzos3	194	13	and	and	CC
cord-003614-63rzzos3	194	14	only	only	RB
cord-003614-63rzzos3	194	15	weakly	weakly	RB
cord-003614-63rzzos3	194	16	up	up	RB
cord-003614-63rzzos3	194	17	-	-	HYPH
cord-003614-63rzzos3	194	18	regulated	regulate	VBN
cord-003614-63rzzos3	194	19	in	in	IN
cord-003614-63rzzos3	194	20	a	a	DT
cord-003614-63rzzos3	194	21	chronic	chronic	JJ
cord-003614-63rzzos3	194	22	lesion	lesion	NN
cord-003614-63rzzos3	194	23	,	,	,
cord-003614-63rzzos3	194	24	but	but	CC
cord-003614-63rzzos3	194	25	microarray	microarray	NN
cord-003614-63rzzos3	194	26	analysis	analysis	NN
cord-003614-63rzzos3	194	27	revealed	reveal	VBD
cord-003614-63rzzos3	194	28	a	a	DT
cord-003614-63rzzos3	194	29	moderate	moderate	JJ
cord-003614-63rzzos3	194	30	increase	increase	NN
cord-003614-63rzzos3	194	31	in	in	IN
cord-003614-63rzzos3	194	32	STAT2	STAT2	NNS
cord-003614-63rzzos3	195	1	mRNA	mRNA	NNP
cord-003614-63rzzos3	195	2	transcripts	transcript	NNS
cord-003614-63rzzos3	195	3	also	also	RB
cord-003614-63rzzos3	195	4	in	in	IN
cord-003614-63rzzos3	195	5	acute	acute	JJ
cord-003614-63rzzos3	195	6	and	and	CC
cord-003614-63rzzos3	195	7	subacute	subacute	JJ
cord-003614-63rzzos3	195	8	lesions	lesion	NNS
cord-003614-63rzzos3	195	9	.	.	.
cord-003614-63rzzos3	196	1	However	however	RB
cord-003614-63rzzos3	196	2	,	,	,
cord-003614-63rzzos3	196	3	the	the	DT
cord-003614-63rzzos3	196	4	antibody	antibody	NN
cord-003614-63rzzos3	196	5	used	use	VBD
cord-003614-63rzzos3	196	6	to	to	TO
cord-003614-63rzzos3	196	7	detect	detect	VB
cord-003614-63rzzos3	196	8	STAT1	stat1	NN
cord-003614-63rzzos3	196	9	only	only	RB
cord-003614-63rzzos3	196	10	binds	bind	VBZ
cord-003614-63rzzos3	196	11	to	to	IN
cord-003614-63rzzos3	196	12	phosphorylated	phosphorylated	JJ
cord-003614-63rzzos3	196	13	and	and	CC
cord-003614-63rzzos3	196	14	thus	thus	RB
cord-003614-63rzzos3	196	15	activated	activate	VBN
cord-003614-63rzzos3	196	16	proteins	protein	NNS
cord-003614-63rzzos3	196	17	(	(	-LRB-
cord-003614-63rzzos3	196	18	p84	p84	CD
cord-003614-63rzzos3	196	19	/	/	SYM
cord-003614-63rzzos3	196	20	p91	p91	NN
cord-003614-63rzzos3	196	21	)	)	-RRB-
cord-003614-63rzzos3	196	22	,	,	,
cord-003614-63rzzos3	196	23	whereas	whereas	IN
cord-003614-63rzzos3	196	24	the	the	DT
cord-003614-63rzzos3	196	25	anti	anti	NNS
cord-003614-63rzzos3	196	26	-	-	JJ
cord-003614-63rzzos3	196	27	STAT2	STAT2	NNS
cord-003614-63rzzos3	196	28	antibody	antibody	NN
cord-003614-63rzzos3	196	29	recognizes	recognize	VBZ
cord-003614-63rzzos3	196	30	activated	activate	VBN
cord-003614-63rzzos3	196	31	and	and	CC
cord-003614-63rzzos3	196	32	non	non	JJ
cord-003614-63rzzos3	196	33	-	-	JJ
cord-003614-63rzzos3	196	34	activated	activate	VBN
cord-003614-63rzzos3	196	35	proteins	protein	NNS
cord-003614-63rzzos3	196	36	.	.	.
cord-003614-63rzzos3	197	1	This	this	DT
cord-003614-63rzzos3	197	2	difference	difference	NN
cord-003614-63rzzos3	197	3	explains	explain	VBZ
cord-003614-63rzzos3	197	4	the	the	DT
cord-003614-63rzzos3	197	5	detection	detection	NN
cord-003614-63rzzos3	197	6	of	of	IN
cord-003614-63rzzos3	197	7	less	less	RBR
cord-003614-63rzzos3	197	8	prominent	prominent	JJ
cord-003614-63rzzos3	197	9	changes	change	NNS
cord-003614-63rzzos3	197	10	in	in	IN
cord-003614-63rzzos3	197	11	STAT2	STAT2	NNS
cord-003614-63rzzos3	197	12	compared	compare	VBN
cord-003614-63rzzos3	197	13	to	to	TO
cord-003614-63rzzos3	197	14	STAT1	stat1	VB
cord-003614-63rzzos3	197	15	protein	protein	NN
cord-003614-63rzzos3	197	16	expression	expression	NN
cord-003614-63rzzos3	197	17	using	use	VBG
cord-003614-63rzzos3	197	18	immunohistochemistry	immunohistochemistry	NN
cord-003614-63rzzos3	197	19	.	.	.
cord-003614-63rzzos3	198	1	Interestingly	interestingly	RB
cord-003614-63rzzos3	198	2	,	,	,
cord-003614-63rzzos3	198	3	both	both	DT
cord-003614-63rzzos3	198	4	transcription	transcription	NN
cord-003614-63rzzos3	198	5	factors	factor	NNS
cord-003614-63rzzos3	198	6	were	be	VBD
cord-003614-63rzzos3	198	7	found	find	VBN
cord-003614-63rzzos3	198	8	in	in	IN
cord-003614-63rzzos3	198	9	neurons	neuron	NNS
cord-003614-63rzzos3	198	10	,	,	,
cord-003614-63rzzos3	198	11	oligodendrocytes	oligodendrocyte	NNS
cord-003614-63rzzos3	198	12	and	and	CC
cord-003614-63rzzos3	198	13	activated	activate	VBN
cord-003614-63rzzos3	198	14	microglia	microglia	NNS
cord-003614-63rzzos3	198	15	/	/	SYM
cord-003614-63rzzos3	198	16	macrophages	macrophage	NNS
cord-003614-63rzzos3	198	17	,	,	,
cord-003614-63rzzos3	198	18	whereas	whereas	IN
cord-003614-63rzzos3	198	19	astrocytes	astrocyte	NNS
cord-003614-63rzzos3	198	20	,	,	,
cord-003614-63rzzos3	198	21	endothelial	endothelial	JJ
cord-003614-63rzzos3	198	22	cells	cell	NNS
cord-003614-63rzzos3	198	23	and	and	CC
cord-003614-63rzzos3	198	24	inflammatory	inflammatory	JJ
cord-003614-63rzzos3	198	25	cells	cell	NNS
cord-003614-63rzzos3	198	26	only	only	RB
cord-003614-63rzzos3	198	27	expressed	express	VBD
cord-003614-63rzzos3	198	28	STAT1	stat1	NN
cord-003614-63rzzos3	198	29	but	but	CC
cord-003614-63rzzos3	198	30	not	not	RB
cord-003614-63rzzos3	198	31	STAT2	STAT2	NNS
cord-003614-63rzzos3	198	32	.	.	.
cord-003614-63rzzos3	199	1	This	this	DT
cord-003614-63rzzos3	199	2	observation	observation	NN
cord-003614-63rzzos3	199	3	suggests	suggest	VBZ
cord-003614-63rzzos3	199	4	that	that	IN
cord-003614-63rzzos3	199	5	the	the	DT
cord-003614-63rzzos3	199	6	canonical	canonical	JJ
cord-003614-63rzzos3	199	7	IFN	IFN	NNP
cord-003614-63rzzos3	199	8	-	-	HYPH
cord-003614-63rzzos3	199	9	I	-PRON-	PRP
cord-003614-63rzzos3	199	10	pathway	pathway	VBP
cord-003614-63rzzos3	199	11	with	with	IN
cord-003614-63rzzos3	199	12	STAT1	stat1	NN
cord-003614-63rzzos3	199	13	/	/	SYM
cord-003614-63rzzos3	199	14	STAT2	STAT2	NNS
cord-003614-63rzzos3	199	15	heterodimer	heterodimer	NN
cord-003614-63rzzos3	199	16	formation	formation	NN
cord-003614-63rzzos3	199	17	only	only	RB
cord-003614-63rzzos3	199	18	plays	play	VBZ
cord-003614-63rzzos3	199	19	a	a	DT
cord-003614-63rzzos3	199	20	minor	minor	JJ
cord-003614-63rzzos3	199	21	role	role	NN
cord-003614-63rzzos3	199	22	in	in	IN
cord-003614-63rzzos3	199	23	the	the	DT
cord-003614-63rzzos3	199	24	latter	latter	JJ
cord-003614-63rzzos3	199	25	cells	cell	NNS
cord-003614-63rzzos3	199	26	and	and	CC
cord-003614-63rzzos3	199	27	non	non	JJ
cord-003614-63rzzos3	199	28	-	-	JJ
cord-003614-63rzzos3	199	29	canonical	canonical	JJ
cord-003614-63rzzos3	199	30	JAK	JAK	NNP
cord-003614-63rzzos3	199	31	-	-	HYPH
cord-003614-63rzzos3	199	32	STAT	stat	NN
cord-003614-63rzzos3	199	33	signaling	signal	VBG
cord-003614-63rzzos3	199	34	via	via	IN
cord-003614-63rzzos3	199	35	STAT1	stat1	NN
cord-003614-63rzzos3	199	36	/	/	SYM
cord-003614-63rzzos3	199	37	STAT1	STAT1	NNP
cord-003614-63rzzos3	199	38	homodimers	homodimer	NNS
cord-003614-63rzzos3	199	39	or	or	CC
cord-003614-63rzzos3	199	40	other	other	JJ
cord-003614-63rzzos3	199	41	pathways	pathway	NNS
cord-003614-63rzzos3	199	42	might	may	MD
cord-003614-63rzzos3	199	43	mediate	mediate	VB
cord-003614-63rzzos3	199	44	ISG	ISG	NNP
cord-003614-63rzzos3	199	45	expression	expression	NN
cord-003614-63rzzos3	199	46	[	[	-LRB-
cord-003614-63rzzos3	199	47	40	40	CD
cord-003614-63rzzos3	199	48	]	]	-RRB-
cord-003614-63rzzos3	199	49	.	.	.
cord-003614-63rzzos3	200	1	Moreover	moreover	RB
cord-003614-63rzzos3	200	2	,	,	,
cord-003614-63rzzos3	200	3	the	the	DT
cord-003614-63rzzos3	200	4	present	present	JJ
cord-003614-63rzzos3	200	5	analysis	analysis	NN
cord-003614-63rzzos3	200	6	of	of	IN
cord-003614-63rzzos3	200	7	the	the	DT
cord-003614-63rzzos3	200	8	previously	previously	RB
cord-003614-63rzzos3	200	9	published	publish	VBN
cord-003614-63rzzos3	200	10	microarray	microarray	NN
cord-003614-63rzzos3	200	11	did	do	VBD
cord-003614-63rzzos3	200	12	not	not	RB
cord-003614-63rzzos3	200	13	detect	detect	VB
cord-003614-63rzzos3	200	14	an	an	DT
cord-003614-63rzzos3	200	15	increase	increase	NN
cord-003614-63rzzos3	200	16	in	in	IN
cord-003614-63rzzos3	200	17	IFN	IFN	NNP
cord-003614-63rzzos3	200	18	-	-	HYPH
cord-003614-63rzzos3	200	19	I	-PRON-	PRP
cord-003614-63rzzos3	200	20	expression	expression	NN
cord-003614-63rzzos3	200	21	in	in	IN
cord-003614-63rzzos3	200	22	the	the	DT
cord-003614-63rzzos3	200	23	CDV	CDV	NNP
cord-003614-63rzzos3	200	24	-	-	HYPH
cord-003614-63rzzos3	200	25	infected	infect	VBN
cord-003614-63rzzos3	200	26	cerebellum	cerebellum	NN
cord-003614-63rzzos3	200	27	,	,	,
cord-003614-63rzzos3	200	28	which	which	WDT
cord-003614-63rzzos3	200	29	is	be	VBZ
cord-003614-63rzzos3	200	30	most	most	RBS
cord-003614-63rzzos3	200	31	likely	likely	RB
cord-003614-63rzzos3	200	32	caused	cause	VBN
cord-003614-63rzzos3	200	33	by	by	IN
cord-003614-63rzzos3	200	34	the	the	DT
cord-003614-63rzzos3	200	35	non	non	JJ
cord-003614-63rzzos3	200	36	-	-	JJ
cord-003614-63rzzos3	200	37	structural	structural	JJ
cord-003614-63rzzos3	200	38	V	v	NN
cord-003614-63rzzos3	200	39	protein	protein	NN
cord-003614-63rzzos3	200	40	of	of	IN
cord-003614-63rzzos3	200	41	CDV	CDV	NNP
cord-003614-63rzzos3	200	42	interfering	interfere	VBG
cord-003614-63rzzos3	200	43	with	with	IN
cord-003614-63rzzos3	200	44	MDA5-dependent	MDA5-dependent	NNP
cord-003614-63rzzos3	200	45	virus	virus	NN
cord-003614-63rzzos3	200	46	detection	detection	NN
cord-003614-63rzzos3	200	47	[	[	-LRB-
cord-003614-63rzzos3	200	48	45	45	CD
cord-003614-63rzzos3	200	49	]	]	-RRB-
cord-003614-63rzzos3	200	50	.	.	.
cord-003614-63rzzos3	201	1	Consequently	consequently	RB
cord-003614-63rzzos3	201	2	,	,	,
cord-003614-63rzzos3	201	3	the	the	DT
cord-003614-63rzzos3	201	4	IFN	IFN	NNP
cord-003614-63rzzos3	201	5	-	-	HYPH
cord-003614-63rzzos3	201	6	I	-PRON-	PRP
cord-003614-63rzzos3	201	7	response	response	NN
cord-003614-63rzzos3	201	8	and	and	CC
cord-003614-63rzzos3	201	9	the	the	DT
cord-003614-63rzzos3	201	10	down	down	JJ
cord-003614-63rzzos3	201	11	-	-	HYPH
cord-003614-63rzzos3	201	12	stream	stream	NN
cord-003614-63rzzos3	201	13	JAK	JAK	NNP
cord-003614-63rzzos3	201	14	-	-	HYPH
cord-003614-63rzzos3	201	15	STAT	stat	NN
cord-003614-63rzzos3	201	16	signaling	signal	VBG
cord-003614-63rzzos3	201	17	cascade	cascade	NN
cord-003614-63rzzos3	201	18	are	be	VBP
cord-003614-63rzzos3	201	19	blocked	block	VBN
cord-003614-63rzzos3	201	20	during	during	IN
cord-003614-63rzzos3	201	21	canine	canine	JJ
cord-003614-63rzzos3	201	22	distemper	distemper	NN
cord-003614-63rzzos3	201	23	encephalitis	encephalitis	RB
cord-003614-63rzzos3	201	24	.	.	.
cord-003614-63rzzos3	202	1	Nevertheless	nevertheless	RB
cord-003614-63rzzos3	202	2	,	,	,
cord-003614-63rzzos3	202	3	the	the	DT
cord-003614-63rzzos3	202	4	present	present	JJ
cord-003614-63rzzos3	202	5	study	study	NN
cord-003614-63rzzos3	202	6	demonstrated	demonstrate	VBD
cord-003614-63rzzos3	202	7	a	a	DT
cord-003614-63rzzos3	202	8	strong	strong	JJ
cord-003614-63rzzos3	202	9	increase	increase	NN
cord-003614-63rzzos3	202	10	in	in	IN
cord-003614-63rzzos3	202	11	ISG	ISG	NNP
cord-003614-63rzzos3	202	12	gene	gene	NN
cord-003614-63rzzos3	202	13	and	and	CC
cord-003614-63rzzos3	202	14	protein	protein	NN
cord-003614-63rzzos3	202	15	expression	expression	NN
cord-003614-63rzzos3	202	16	,	,	,
cord-003614-63rzzos3	202	17	which	which	WDT
cord-003614-63rzzos3	202	18	seems	seem	VBZ
cord-003614-63rzzos3	202	19	to	to	TO
cord-003614-63rzzos3	202	20	be	be	VB
cord-003614-63rzzos3	202	21	mediated	mediate	VBN
cord-003614-63rzzos3	202	22	by	by	IN
cord-003614-63rzzos3	202	23	IFN	IFN	NNP
cord-003614-63rzzos3	202	24	-	-	HYPH
cord-003614-63rzzos3	202	25	I	I	NNP
cord-003614-63rzzos3	202	26	-	-	HYPH
cord-003614-63rzzos3	202	27	independent	independent	JJ
cord-003614-63rzzos3	202	28	pathways	pathway	NNS
cord-003614-63rzzos3	202	29	.	.	.
cord-003614-63rzzos3	203	1	Similarly	similarly	RB
cord-003614-63rzzos3	203	2	,	,	,
cord-003614-63rzzos3	203	3	a	a	DT
cord-003614-63rzzos3	203	4	recent	recent	JJ
cord-003614-63rzzos3	203	5	microarray	microarray	NN
cord-003614-63rzzos3	203	6	study	study	NN
cord-003614-63rzzos3	203	7	of	of	IN
cord-003614-63rzzos3	203	8	mice	mouse	NNS
cord-003614-63rzzos3	203	9	infected	infect	VBN
cord-003614-63rzzos3	203	10	by	by	IN
cord-003614-63rzzos3	203	11	Theiler	Theiler	NNP
cord-003614-63rzzos3	203	12	's	's	POS
cord-003614-63rzzos3	203	13	murine	murine	JJ
cord-003614-63rzzos3	203	14	encephalomyelitis	encephalomyelitis	NN
cord-003614-63rzzos3	203	15	virus	virus	NN
cord-003614-63rzzos3	203	16	(	(	-LRB-
cord-003614-63rzzos3	203	17	TMEV	TMEV	NNP
cord-003614-63rzzos3	203	18	)	)	-RRB-
cord-003614-63rzzos3	203	19	described	describe	VBD
cord-003614-63rzzos3	203	20	a	a	DT
cord-003614-63rzzos3	203	21	strong	strong	JJ
cord-003614-63rzzos3	203	22	ISG	ISG	NNP
cord-003614-63rzzos3	203	23	expression	expression	NN
cord-003614-63rzzos3	203	24	in	in	IN
cord-003614-63rzzos3	203	25	demyelinating	demyelinating	JJ
cord-003614-63rzzos3	203	26	spinal	spinal	JJ
cord-003614-63rzzos3	203	27	cord	cord	NN
cord-003614-63rzzos3	203	28	lesions	lesion	NNS
cord-003614-63rzzos3	203	29	despite	despite	IN
cord-003614-63rzzos3	203	30	low	low	JJ
cord-003614-63rzzos3	203	31	IFN	IFN	NNP
cord-003614-63rzzos3	203	32	-	-	HYPH
cord-003614-63rzzos3	203	33	I	-PRON-	PRP
cord-003614-63rzzos3	203	34	levels	level	NNS
cord-003614-63rzzos3	203	35	[	[	-LRB-
cord-003614-63rzzos3	203	36	62	62	CD
cord-003614-63rzzos3	203	37	]	]	-RRB-
cord-003614-63rzzos3	203	38	.	.	.
cord-003614-63rzzos3	204	1	ISG15	ISG15	NNP
cord-003614-63rzzos3	204	2	expression	expression	NN
cord-003614-63rzzos3	204	3	can	can	MD
cord-003614-63rzzos3	204	4	directly	directly	RB
cord-003614-63rzzos3	204	5	be	be	VB
cord-003614-63rzzos3	204	6	induced	induce	VBN
cord-003614-63rzzos3	204	7	by	by	IN
cord-003614-63rzzos3	204	8	IRF1	IRF1	NNP
cord-003614-63rzzos3	204	9	(	(	-LRB-
cord-003614-63rzzos3	204	10	formerly	formerly	RB
cord-003614-63rzzos3	204	11	called	call	VBN
cord-003614-63rzzos3	204	12	ISGF2	ISGF2	NNP
cord-003614-63rzzos3	204	13	)	)	-RRB-
cord-003614-63rzzos3	204	14	,	,	,
cord-003614-63rzzos3	204	15	which	which	WDT
cord-003614-63rzzos3	204	16	is	be	VBZ
cord-003614-63rzzos3	204	17	a	a	DT
cord-003614-63rzzos3	204	18	transcription	transcription	NN
cord-003614-63rzzos3	204	19	factor	factor	NN
cord-003614-63rzzos3	204	20	involved	involve	VBN
cord-003614-63rzzos3	204	21	in	in	IN
cord-003614-63rzzos3	204	22	anti	anti	JJ
cord-003614-63rzzos3	204	23	-	-	JJ
cord-003614-63rzzos3	204	24	viral	viral	JJ
cord-003614-63rzzos3	204	25	and	and	CC
cord-003614-63rzzos3	204	26	anti	anti	JJ
cord-003614-63rzzos3	204	27	-	-	JJ
cord-003614-63rzzos3	204	28	bacterial	bacterial	JJ
cord-003614-63rzzos3	204	29	immune	immune	JJ
cord-003614-63rzzos3	204	30	responses	response	NNS
cord-003614-63rzzos3	204	31	,	,	,
cord-003614-63rzzos3	204	32	T	t	NN
cord-003614-63rzzos3	204	33	cell	cell	NN
cord-003614-63rzzos3	204	34	and	and	CC
cord-003614-63rzzos3	204	35	NK	NK	NNP
cord-003614-63rzzos3	204	36	cell	cell	NN
cord-003614-63rzzos3	204	37	differentiation	differentiation	NN
cord-003614-63rzzos3	204	38	,	,	,
cord-003614-63rzzos3	204	39	MHC	MHC	NNP
cord-003614-63rzzos3	204	40	class	class	NN
cord-003614-63rzzos3	204	41	I	i	NN
cord-003614-63rzzos3	204	42	and	and	CC
cord-003614-63rzzos3	204	43	II	ii	CD
cord-003614-63rzzos3	204	44	expression	expression	NN
cord-003614-63rzzos3	204	45	and	and	CC
cord-003614-63rzzos3	204	46	induction	induction	NN
cord-003614-63rzzos3	204	47	of	of	IN
cord-003614-63rzzos3	204	48	apoptosis	apoptosis	NN
cord-003614-63rzzos3	204	49	[	[	-LRB-
cord-003614-63rzzos3	204	50	55	55	CD
cord-003614-63rzzos3	204	51	,	,	,
cord-003614-63rzzos3	204	52	63	63	CD
cord-003614-63rzzos3	204	53	,	,	,
cord-003614-63rzzos3	204	54	64	64	CD
cord-003614-63rzzos3	204	55	]	]	-RRB-
cord-003614-63rzzos3	204	56	.	.	.
cord-003614-63rzzos3	205	1	Correspondingly	correspondingly	RB
cord-003614-63rzzos3	205	2	,	,	,
cord-003614-63rzzos3	205	3	the	the	DT
cord-003614-63rzzos3	205	4	present	present	JJ
cord-003614-63rzzos3	205	5	canine	canine	JJ
cord-003614-63rzzos3	205	6	study	study	NN
cord-003614-63rzzos3	205	7	demonstrated	demonstrate	VBD
cord-003614-63rzzos3	205	8	a	a	DT
cord-003614-63rzzos3	205	9	strong	strong	JJ
cord-003614-63rzzos3	205	10	up	up	NN
cord-003614-63rzzos3	205	11	-	-	HYPH
cord-003614-63rzzos3	205	12	regulation	regulation	NN
cord-003614-63rzzos3	205	13	of	of	IN
cord-003614-63rzzos3	205	14	IRF1	IRF1	NNP
cord-003614-63rzzos3	205	15	and	and	CC
cord-003614-63rzzos3	205	16	several	several	JJ
cord-003614-63rzzos3	205	17	MHC	MHC	NNP
cord-003614-63rzzos3	205	18	genes	gene	NNS
cord-003614-63rzzos3	205	19	at	at	IN
cord-003614-63rzzos3	205	20	all	all	DT
cord-003614-63rzzos3	205	21	stages	stage	NNS
cord-003614-63rzzos3	205	22	of	of	IN
cord-003614-63rzzos3	205	23	CDV	CDV	NNP
cord-003614-63rzzos3	205	24	-	-	HYPH
cord-003614-63rzzos3	205	25	induced	induce	VBN
cord-003614-63rzzos3	205	26	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	205	27	lesions	lesion	NNS
cord-003614-63rzzos3	205	28	.	.	.
cord-003614-63rzzos3	206	1	DLA-88	DLA-88	NNP
cord-003614-63rzzos3	206	2	was	be	VBD
cord-003614-63rzzos3	206	3	particularly	particularly	RB
cord-003614-63rzzos3	206	4	increased	increase	VBN
cord-003614-63rzzos3	206	5	in	in	IN
cord-003614-63rzzos3	206	6	acute	acute	JJ
cord-003614-63rzzos3	206	7	and	and	CC
cord-003614-63rzzos3	206	8	subacute	subacute	JJ
cord-003614-63rzzos3	206	9	distemper	distemper	NN
cord-003614-63rzzos3	206	10	lesions	lesion	NNS
cord-003614-63rzzos3	206	11	(	(	-LRB-
cord-003614-63rzzos3	206	12	fold	fold	VB
cord-003614-63rzzos3	206	13	change	change	NN
cord-003614-63rzzos3	206	14	up	up	IN
cord-003614-63rzzos3	206	15	to	to	IN
cord-003614-63rzzos3	206	16	135,55	135,55	NNP
cord-003614-63rzzos3	206	17	)	)	-RRB-
cord-003614-63rzzos3	206	18	.	.	.
cord-003614-63rzzos3	207	1	Most	most	RBS
cord-003614-63rzzos3	207	2	importantly	importantly	RB
cord-003614-63rzzos3	207	3	,	,	,
cord-003614-63rzzos3	207	4	this	this	DT
cord-003614-63rzzos3	207	5	highly	highly	RB
cord-003614-63rzzos3	207	6	polymorphic	polymorphic	JJ
cord-003614-63rzzos3	207	7	MHC	MHC	NNP
cord-003614-63rzzos3	207	8	class	class	NN
cord-003614-63rzzos3	208	1	I	-PRON-	PRP
cord-003614-63rzzos3	208	2	protein	protein	NN
cord-003614-63rzzos3	208	3	can	can	MD
cord-003614-63rzzos3	208	4	present	present	VB
cord-003614-63rzzos3	208	5	peptides	peptide	NNS
cord-003614-63rzzos3	208	6	derived	derive	VBN
cord-003614-63rzzos3	208	7	from	from	IN
cord-003614-63rzzos3	208	8	CDV	CDV	NNP
cord-003614-63rzzos3	208	9	hemagglutinin	hemagglutinin	NN
cord-003614-63rzzos3	208	10	,	,	,
cord-003614-63rzzos3	208	11	large	large	JJ
cord-003614-63rzzos3	208	12	polymerase	polymerase	NN
cord-003614-63rzzos3	208	13	,	,	,
cord-003614-63rzzos3	208	14	matrix	matrix	NN
cord-003614-63rzzos3	208	15	,	,	,
cord-003614-63rzzos3	208	16	nucleocapsid	nucleocapsid	NN
cord-003614-63rzzos3	208	17	,	,	,
cord-003614-63rzzos3	208	18	and	and	CC
cord-003614-63rzzos3	208	19	V	v	NN
cord-003614-63rzzos3	208	20	proteins	protein	NNS
cord-003614-63rzzos3	208	21	[	[	-LRB-
cord-003614-63rzzos3	208	22	65	65	CD
cord-003614-63rzzos3	208	23	,	,	,
cord-003614-63rzzos3	208	24	66	66	CD
cord-003614-63rzzos3	208	25	]	]	-RRB-
cord-003614-63rzzos3	208	26	.	.	.
cord-003614-63rzzos3	209	1	IRF7	IRF7	NNP
cord-003614-63rzzos3	209	2	is	be	VBZ
cord-003614-63rzzos3	209	3	also	also	RB
cord-003614-63rzzos3	209	4	described	describe	VBN
cord-003614-63rzzos3	209	5	as	as	IN
cord-003614-63rzzos3	209	6	inducing	induce	VBG
cord-003614-63rzzos3	209	7	ISG	ISG	NNP
cord-003614-63rzzos3	209	8	transcription	transcription	NN
cord-003614-63rzzos3	209	9	in	in	IN
cord-003614-63rzzos3	209	10	the	the	DT
cord-003614-63rzzos3	209	11	absence	absence	NN
cord-003614-63rzzos3	209	12	of	of	IN
cord-003614-63rzzos3	209	13	IFN	IFN	NNP
cord-003614-63rzzos3	209	14	-	-	HYPH
cord-003614-63rzzos3	209	15	I	I	NNP
cord-003614-63rzzos3	209	16	[	[	-LRB-
cord-003614-63rzzos3	209	17	67	67	CD
cord-003614-63rzzos3	209	18	]	]	-RRB-
cord-003614-63rzzos3	209	19	.	.	.
cord-003614-63rzzos3	210	1	Consequently	consequently	RB
cord-003614-63rzzos3	210	2	,	,	,
cord-003614-63rzzos3	210	3	IRF1-and	IRF1-and	NNP
cord-003614-63rzzos3	210	4	IRF7-dependent	IRF7-dependent	NNP
cord-003614-63rzzos3	210	5	pathways	pathway	NNS
cord-003614-63rzzos3	210	6	presumably	presumably	RB
cord-003614-63rzzos3	210	7	mediate	mediate	VBP
cord-003614-63rzzos3	210	8	a	a	DT
cord-003614-63rzzos3	210	9	major	major	JJ
cord-003614-63rzzos3	210	10	part	part	NN
cord-003614-63rzzos3	210	11	of	of	IN
cord-003614-63rzzos3	210	12	ISG	ISG	NNP
cord-003614-63rzzos3	210	13	expression	expression	NN
cord-003614-63rzzos3	210	14	in	in	IN
cord-003614-63rzzos3	210	15	the	the	DT
cord-003614-63rzzos3	210	16	CDV	CDV	NNP
cord-003614-63rzzos3	210	17	-	-	HYPH
cord-003614-63rzzos3	210	18	infected	infect	VBN
cord-003614-63rzzos3	210	19	cerebellum	cerebellum	NN
cord-003614-63rzzos3	210	20	,	,	,
cord-003614-63rzzos3	210	21	counteracting	counteract	VBG
cord-003614-63rzzos3	210	22	common	common	JJ
cord-003614-63rzzos3	210	23	viral	viral	JJ
cord-003614-63rzzos3	210	24	strategies	strategy	NNS
cord-003614-63rzzos3	210	25	,	,	,
cord-003614-63rzzos3	210	26	which	which	WDT
cord-003614-63rzzos3	210	27	modulate	modulate	VBP
cord-003614-63rzzos3	210	28	or	or	CC
cord-003614-63rzzos3	210	29	inhibit	inhibit	VB
cord-003614-63rzzos3	210	30	the	the	DT
cord-003614-63rzzos3	210	31	IFN	IFN	NNP
cord-003614-63rzzos3	210	32	-	-	HYPH
cord-003614-63rzzos3	210	33	I	-PRON-	PRP
cord-003614-63rzzos3	210	34	response	response	NN
cord-003614-63rzzos3	210	35	[	[	-LRB-
cord-003614-63rzzos3	210	36	67	67	CD
cord-003614-63rzzos3	210	37	,	,	,
cord-003614-63rzzos3	210	38	68	68	CD
cord-003614-63rzzos3	210	39	]	]	-RRB-
cord-003614-63rzzos3	210	40	.	.	.
cord-003614-63rzzos3	211	1	ISG15	ISG15	NNP
cord-003614-63rzzos3	211	2	showed	show	VBD
cord-003614-63rzzos3	211	3	the	the	DT
cord-003614-63rzzos3	211	4	strongest	strong	JJS
cord-003614-63rzzos3	211	5	increase	increase	NN
cord-003614-63rzzos3	211	6	of	of	IN
cord-003614-63rzzos3	211	7	all	all	DT
cord-003614-63rzzos3	211	8	investigated	investigate	VBN
cord-003614-63rzzos3	211	9	genes	gene	NNS
cord-003614-63rzzos3	211	10	,	,	,
cord-003614-63rzzos3	211	11	with	with	IN
cord-003614-63rzzos3	211	12	a	a	DT
cord-003614-63rzzos3	211	13	fold	fold	JJ
cord-003614-63rzzos3	211	14	change	change	NN
cord-003614-63rzzos3	211	15	of	of	IN
cord-003614-63rzzos3	211	16	almost	almost	RB
cord-003614-63rzzos3	211	17	1000	1000	CD
cord-003614-63rzzos3	211	18	in	in	IN
cord-003614-63rzzos3	211	19	subacute	subacute	JJ
cord-003614-63rzzos3	211	20	lesions	lesion	NNS
cord-003614-63rzzos3	211	21	.	.	.
cord-003614-63rzzos3	212	1	In	in	IN
cord-003614-63rzzos3	212	2	addition	addition	NN
cord-003614-63rzzos3	212	3	,	,	,
cord-003614-63rzzos3	212	4	a	a	DT
cord-003614-63rzzos3	212	5	weak	weak	JJ
cord-003614-63rzzos3	212	6	ISG15	ISG15	NNP
cord-003614-63rzzos3	212	7	immunoreactivity	immunoreactivity	NN
cord-003614-63rzzos3	212	8	was	be	VBD
cord-003614-63rzzos3	212	9	detected	detect	VBN
cord-003614-63rzzos3	212	10	in	in	IN
cord-003614-63rzzos3	212	11	neurons	neuron	NNS
cord-003614-63rzzos3	212	12	and	and	CC
cord-003614-63rzzos3	212	13	endothelial	endothelial	JJ
cord-003614-63rzzos3	212	14	cells	cell	NNS
cord-003614-63rzzos3	212	15	of	of	IN
cord-003614-63rzzos3	212	16	uninfected	uninfected	JJ
cord-003614-63rzzos3	212	17	canine	canine	JJ
cord-003614-63rzzos3	212	18	cerebella	cerebellum	NNS
cord-003614-63rzzos3	212	19	,	,	,
cord-003614-63rzzos3	212	20	confirming	confirm	VBG
cord-003614-63rzzos3	212	21	previous	previous	JJ
cord-003614-63rzzos3	212	22	descriptions	description	NNS
cord-003614-63rzzos3	212	23	of	of	IN
cord-003614-63rzzos3	212	24	a	a	DT
cord-003614-63rzzos3	212	25	low	low	JJ
cord-003614-63rzzos3	212	26	constitutive	constitutive	JJ
cord-003614-63rzzos3	212	27	ISG15	isg15	NN
cord-003614-63rzzos3	212	28	expression	expression	NN
cord-003614-63rzzos3	212	29	[	[	-LRB-
cord-003614-63rzzos3	212	30	69	69	CD
cord-003614-63rzzos3	212	31	]	]	-RRB-
cord-003614-63rzzos3	212	32	.	.	.
cord-003614-63rzzos3	213	1	ISG15	ISG15	NNP
cord-003614-63rzzos3	213	2	represents	represent	VBZ
cord-003614-63rzzos3	213	3	an	an	DT
cord-003614-63rzzos3	213	4	ubiquitin	ubiquitin	NN
cord-003614-63rzzos3	213	5	-	-	HYPH
cord-003614-63rzzos3	213	6	like	like	JJ
cord-003614-63rzzos3	213	7	protein	protein	NN
cord-003614-63rzzos3	213	8	,	,	,
cord-003614-63rzzos3	213	9	which	which	WDT
cord-003614-63rzzos3	213	10	binds	bind	VBZ
cord-003614-63rzzos3	213	11	to	to	IN
cord-003614-63rzzos3	213	12	over	over	IN
cord-003614-63rzzos3	213	13	150	150	CD
cord-003614-63rzzos3	213	14	cellular	cellular	JJ
cord-003614-63rzzos3	213	15	proteins	protein	NNS
cord-003614-63rzzos3	213	16	involved	involve	VBN
cord-003614-63rzzos3	213	17	in	in	IN
cord-003614-63rzzos3	213	18	immune	immune	JJ
cord-003614-63rzzos3	213	19	regulation	regulation	NN
cord-003614-63rzzos3	213	20	,	,	,
cord-003614-63rzzos3	213	21	including	include	VBG
cord-003614-63rzzos3	213	22	members	member	NNS
cord-003614-63rzzos3	213	23	of	of	IN
cord-003614-63rzzos3	213	24	the	the	DT
cord-003614-63rzzos3	213	25	IFN	IFN	NNP
cord-003614-63rzzos3	213	26	-	-	HYPH
cord-003614-63rzzos3	213	27	I	I	NNP
cord-003614-63rzzos3	213	28	,	,	,
cord-003614-63rzzos3	213	29	NF	NF	NNP
cord-003614-63rzzos3	213	30	-	-	HYPH
cord-003614-63rzzos3	213	31	κB	κB	NNP
cord-003614-63rzzos3	213	32	and	and	CC
cord-003614-63rzzos3	213	33	JNK	JNK	NNP
cord-003614-63rzzos3	213	34	pathways	pathway	NNS
cord-003614-63rzzos3	213	35	[	[	-LRB-
cord-003614-63rzzos3	213	36	69	69	CD
cord-003614-63rzzos3	213	37	,	,	,
cord-003614-63rzzos3	213	38	70	70	CD
cord-003614-63rzzos3	213	39	]	]	-RRB-
cord-003614-63rzzos3	213	40	.	.	.
cord-003614-63rzzos3	214	1	This	this	DT
cord-003614-63rzzos3	214	2	process	process	NN
cord-003614-63rzzos3	214	3	known	know	VBN
cord-003614-63rzzos3	214	4	as	as	IN
cord-003614-63rzzos3	214	5	ISGylation	ISGylation	NNP
cord-003614-63rzzos3	214	6	can	can	MD
cord-003614-63rzzos3	214	7	activate	activate	VB
cord-003614-63rzzos3	214	8	or	or	CC
cord-003614-63rzzos3	214	9	inhibit	inhibit	VB
cord-003614-63rzzos3	214	10	the	the	DT
cord-003614-63rzzos3	214	11	respective	respective	JJ
cord-003614-63rzzos3	214	12	signaling	signal	VBG
cord-003614-63rzzos3	214	13	cascades	cascade	NNS
cord-003614-63rzzos3	214	14	in	in	IN
cord-003614-63rzzos3	214	15	a	a	DT
cord-003614-63rzzos3	214	16	species	species	NN
cord-003614-63rzzos3	214	17	-	-	HYPH
cord-003614-63rzzos3	214	18	specific	specific	JJ
cord-003614-63rzzos3	214	19	manner	manner	NN
cord-003614-63rzzos3	214	20	[	[	-LRB-
cord-003614-63rzzos3	214	21	71	71	CD
cord-003614-63rzzos3	214	22	]	]	-RRB-
cord-003614-63rzzos3	214	23	.	.	.
cord-003614-63rzzos3	215	1	Murine	murine	JJ
cord-003614-63rzzos3	215	2	ISG15	isg15	NN
cord-003614-63rzzos3	215	3	targets	target	VBZ
cord-003614-63rzzos3	215	4	RIG1	RIG1	NNP
cord-003614-63rzzos3	215	5	,	,	,
cord-003614-63rzzos3	215	6	which	which	WDT
cord-003614-63rzzos3	215	7	reduces	reduce	VBZ
cord-003614-63rzzos3	215	8	type	type	NN
cord-003614-63rzzos3	215	9	I	-PRON-	PRP
cord-003614-63rzzos3	215	10	interferon	interferon	VBD
cord-003614-63rzzos3	215	11	promoter	promoter	NN
cord-003614-63rzzos3	215	12	activity	activity	NN
cord-003614-63rzzos3	215	13	and	and	CC
cord-003614-63rzzos3	215	14	NF	nf	NN
cord-003614-63rzzos3	215	15	-	-	HYPH
cord-003614-63rzzos3	215	16	κB	κb	CD
cord-003614-63rzzos3	215	17	responses	response	NNS
cord-003614-63rzzos3	215	18	[	[	-LRB-
cord-003614-63rzzos3	215	19	72	72	CD
cord-003614-63rzzos3	215	20	]	]	-RRB-
cord-003614-63rzzos3	215	21	.	.	.
cord-003614-63rzzos3	216	1	In	in	IN
cord-003614-63rzzos3	216	2	contrast	contrast	NN
cord-003614-63rzzos3	216	3	,	,	,
cord-003614-63rzzos3	216	4	human	human	JJ
cord-003614-63rzzos3	216	5	ISG15	isg15	NN
cord-003614-63rzzos3	216	6	can	can	MD
cord-003614-63rzzos3	216	7	bind	bind	VB
cord-003614-63rzzos3	216	8	to	to	IN
cord-003614-63rzzos3	216	9	IRF3	IRF3	NNP
cord-003614-63rzzos3	216	10	preventing	prevent	VBG
cord-003614-63rzzos3	216	11	its	-PRON-	PRP$
cord-003614-63rzzos3	216	12	degradation	degradation	NN
cord-003614-63rzzos3	216	13	by	by	IN
cord-003614-63rzzos3	216	14	the	the	DT
cord-003614-63rzzos3	216	15	proteasome	proteasome	NN
cord-003614-63rzzos3	216	16	and	and	CC
cord-003614-63rzzos3	216	17	thereby	thereby	RB
cord-003614-63rzzos3	216	18	increasing	increase	VBG
cord-003614-63rzzos3	216	19	the	the	DT
cord-003614-63rzzos3	216	20	IFN	IFN	NNP
cord-003614-63rzzos3	216	21	-	-	HYPH
cord-003614-63rzzos3	216	22	I	-PRON-	PRP
cord-003614-63rzzos3	216	23	response	response	NN
cord-003614-63rzzos3	216	24	[	[	-LRB-
cord-003614-63rzzos3	216	25	73	73	CD
cord-003614-63rzzos3	216	26	]	]	-RRB-
cord-003614-63rzzos3	216	27	.	.	.
cord-003614-63rzzos3	217	1	Nevertheless	nevertheless	RB
cord-003614-63rzzos3	217	2	,	,	,
cord-003614-63rzzos3	217	3	humans	human	NNS
cord-003614-63rzzos3	217	4	born	bear	VBN
cord-003614-63rzzos3	217	5	with	with	IN
cord-003614-63rzzos3	217	6	inactivating	inactivate	VBG
cord-003614-63rzzos3	217	7	ISG15	isg15	NN
cord-003614-63rzzos3	217	8	mutations	mutation	NNS
cord-003614-63rzzos3	217	9	are	be	VBP
cord-003614-63rzzos3	217	10	highly	highly	RB
cord-003614-63rzzos3	217	11	susceptible	susceptible	JJ
cord-003614-63rzzos3	217	12	to	to	IN
cord-003614-63rzzos3	217	13	mycobacterial	mycobacterial	NNP
cord-003614-63rzzos3	217	14	and	and	CC
cord-003614-63rzzos3	217	15	autoinflammatory	autoinflammatory	JJ
cord-003614-63rzzos3	217	16	diseases	disease	NNS
cord-003614-63rzzos3	217	17	but	but	CC
cord-003614-63rzzos3	217	18	not	not	RB
cord-003614-63rzzos3	217	19	to	to	IN
cord-003614-63rzzos3	217	20	viruses	virus	NNS
cord-003614-63rzzos3	217	21	,	,	,
cord-003614-63rzzos3	217	22	this	this	DT
cord-003614-63rzzos3	217	23	underlining	underline	VBG
cord-003614-63rzzos3	217	24	the	the	DT
cord-003614-63rzzos3	217	25	complexity	complexity	NN
cord-003614-63rzzos3	217	26	of	of	IN
cord-003614-63rzzos3	217	27	ISG15-mediated	isg15-mediate	VBN
cord-003614-63rzzos3	217	28	effects	effect	NNS
cord-003614-63rzzos3	217	29	[	[	-LRB-
cord-003614-63rzzos3	217	30	71	71	CD
cord-003614-63rzzos3	217	31	,	,	,
cord-003614-63rzzos3	217	32	74	74	CD
cord-003614-63rzzos3	217	33	]	]	-RRB-
cord-003614-63rzzos3	217	34	.	.	.
cord-003614-63rzzos3	218	1	The	the	DT
cord-003614-63rzzos3	218	2	susceptibility	susceptibility	NN
cord-003614-63rzzos3	218	3	of	of	IN
cord-003614-63rzzos3	218	4	ISG15-deficient	isg15-deficient	CD
cord-003614-63rzzos3	218	5	patients	patient	NNS
cord-003614-63rzzos3	218	6	to	to	IN
cord-003614-63rzzos3	218	7	environmental	environmental	JJ
cord-003614-63rzzos3	218	8	mycobacteria	mycobacterium	NNS
cord-003614-63rzzos3	218	9	is	be	VBZ
cord-003614-63rzzos3	218	10	probably	probably	RB
cord-003614-63rzzos3	218	11	related	relate	VBN
cord-003614-63rzzos3	218	12	to	to	IN
cord-003614-63rzzos3	218	13	the	the	DT
cord-003614-63rzzos3	218	14	cytokine	cytokine	NN
cord-003614-63rzzos3	218	15	-	-	HYPH
cord-003614-63rzzos3	218	16	like	like	JJ
cord-003614-63rzzos3	218	17	functions	function	NNS
cord-003614-63rzzos3	218	18	of	of	IN
cord-003614-63rzzos3	218	19	secreted	secrete	VBN
cord-003614-63rzzos3	218	20	ISG15	isg15	NN
cord-003614-63rzzos3	218	21	,	,	,
cord-003614-63rzzos3	218	22	which	which	WDT
cord-003614-63rzzos3	218	23	acts	act	VBZ
cord-003614-63rzzos3	218	24	in	in	IN
cord-003614-63rzzos3	218	25	synergy	synergy	NN
cord-003614-63rzzos3	218	26	with	with	IN
cord-003614-63rzzos3	218	27	IL12	IL12	NNP
cord-003614-63rzzos3	218	28	to	to	TO
cord-003614-63rzzos3	218	29	induce	induce	VB
cord-003614-63rzzos3	218	30	IFNγ	IFNγ	NNS
cord-003614-63rzzos3	218	31	production	production	NN
cord-003614-63rzzos3	218	32	by	by	IN
cord-003614-63rzzos3	218	33	T	T	NNP
cord-003614-63rzzos3	218	34	cells	cell	NNS
cord-003614-63rzzos3	218	35	or	or	CC
cord-003614-63rzzos3	218	36	NK	NK	NNP
cord-003614-63rzzos3	218	37	cells	cell	NNS
cord-003614-63rzzos3	218	38	,	,	,
cord-003614-63rzzos3	218	39	thus	thus	RB
cord-003614-63rzzos3	218	40	enhancing	enhance	VBG
cord-003614-63rzzos3	218	41	the	the	DT
cord-003614-63rzzos3	218	42	antimycobacterial	antimycobacterial	JJ
cord-003614-63rzzos3	218	43	activity	activity	NN
cord-003614-63rzzos3	218	44	of	of	IN
cord-003614-63rzzos3	218	45	macrophages	macrophage	NNS
cord-003614-63rzzos3	218	46	[	[	-LRB-
cord-003614-63rzzos3	218	47	70	70	CD
cord-003614-63rzzos3	218	48	,	,	,
cord-003614-63rzzos3	218	49	71	71	CD
cord-003614-63rzzos3	218	50	,	,	,
cord-003614-63rzzos3	218	51	75	75	CD
cord-003614-63rzzos3	218	52	,	,	,
cord-003614-63rzzos3	218	53	76	76	CD
cord-003614-63rzzos3	218	54	]	]	-RRB-
cord-003614-63rzzos3	218	55	.	.	.
cord-003614-63rzzos3	219	1	Only	only	RB
cord-003614-63rzzos3	219	2	a	a	DT
cord-003614-63rzzos3	219	3	few	few	JJ
cord-003614-63rzzos3	219	4	studies	study	NNS
cord-003614-63rzzos3	219	5	have	have	VBP
cord-003614-63rzzos3	219	6	investigated	investigate	VBN
cord-003614-63rzzos3	219	7	the	the	DT
cord-003614-63rzzos3	219	8	functions	function	NNS
cord-003614-63rzzos3	219	9	of	of	IN
cord-003614-63rzzos3	219	10	ISG15	isg15	NN
cord-003614-63rzzos3	219	11	in	in	IN
cord-003614-63rzzos3	219	12	dogs	dog	NNS
cord-003614-63rzzos3	219	13	,	,	,
cord-003614-63rzzos3	219	14	indicating	indicate	VBG
cord-003614-63rzzos3	219	15	an	an	DT
cord-003614-63rzzos3	219	16	antiviral	antiviral	JJ
cord-003614-63rzzos3	219	17	activity	activity	NN
cord-003614-63rzzos3	219	18	of	of	IN
cord-003614-63rzzos3	219	19	this	this	DT
cord-003614-63rzzos3	219	20	protein	protein	NN
cord-003614-63rzzos3	219	21	in	in	IN
cord-003614-63rzzos3	219	22	canine	canine	JJ
cord-003614-63rzzos3	219	23	cells	cell	NNS
cord-003614-63rzzos3	219	24	,	,	,
cord-003614-63rzzos3	219	25	which	which	WDT
cord-003614-63rzzos3	219	26	might	may	MD
cord-003614-63rzzos3	219	27	be	be	VB
cord-003614-63rzzos3	219	28	mediated	mediate	VBN
cord-003614-63rzzos3	219	29	by	by	IN
cord-003614-63rzzos3	219	30	binding	bind	VBG
cord-003614-63rzzos3	219	31	ISG15	isg15	NN
cord-003614-63rzzos3	219	32	to	to	IN
cord-003614-63rzzos3	219	33	viral	viral	JJ
cord-003614-63rzzos3	219	34	proteins	protein	NNS
cord-003614-63rzzos3	219	35	interfering	interfere	VBG
cord-003614-63rzzos3	219	36	with	with	IN
cord-003614-63rzzos3	219	37	viral	viral	JJ
cord-003614-63rzzos3	219	38	replication	replication	NN
cord-003614-63rzzos3	219	39	[	[	-LRB-
cord-003614-63rzzos3	219	40	17	17	CD
cord-003614-63rzzos3	219	41	,	,	,
cord-003614-63rzzos3	219	42	69	69	CD
cord-003614-63rzzos3	219	43	,	,	,
cord-003614-63rzzos3	219	44	70	70	CD
cord-003614-63rzzos3	219	45	,	,	,
cord-003614-63rzzos3	219	46	77	77	CD
cord-003614-63rzzos3	219	47	]	]	-RRB-
cord-003614-63rzzos3	219	48	.	.	.
cord-003614-63rzzos3	220	1	IFNγ	IFNγ	NNS
cord-003614-63rzzos3	220	2	can	can	MD
cord-003614-63rzzos3	220	3	be	be	VB
cord-003614-63rzzos3	220	4	found	find	VBN
cord-003614-63rzzos3	220	5	in	in	IN
cord-003614-63rzzos3	220	6	the	the	DT
cord-003614-63rzzos3	220	7	CSF	CSF	NNP
cord-003614-63rzzos3	220	8	of	of	IN
cord-003614-63rzzos3	220	9	dogs	dog	NNS
cord-003614-63rzzos3	220	10	with	with	IN
cord-003614-63rzzos3	220	11	chronic	chronic	NN
cord-003614-63rzzos3	220	12	but	but	CC
cord-003614-63rzzos3	220	13	not	not	RB
cord-003614-63rzzos3	220	14	early	early	JJ
cord-003614-63rzzos3	220	15	lesions	lesion	NNS
cord-003614-63rzzos3	220	16	[	[	-LRB-
cord-003614-63rzzos3	220	17	78	78	CD
cord-003614-63rzzos3	220	18	]	]	-RRB-
cord-003614-63rzzos3	220	19	[	[	-LRB-
cord-003614-63rzzos3	220	20	79	79	CD
cord-003614-63rzzos3	220	21	]	]	-RRB-
cord-003614-63rzzos3	220	22	[	[	-LRB-
cord-003614-63rzzos3	220	23	80	80	CD
cord-003614-63rzzos3	220	24	]	]	-RRB-
cord-003614-63rzzos3	220	25	.	.	.
cord-003614-63rzzos3	221	1	Consequently	consequently	RB
cord-003614-63rzzos3	221	2	,	,	,
cord-003614-63rzzos3	221	3	highly	highly	RB
cord-003614-63rzzos3	221	4	up	up	RB
cord-003614-63rzzos3	221	5	-	-	HYPH
cord-003614-63rzzos3	221	6	regulated	regulate	VBN
cord-003614-63rzzos3	221	7	ISG15	isg15	NN
cord-003614-63rzzos3	221	8	levels	level	NNS
cord-003614-63rzzos3	221	9	in	in	IN
cord-003614-63rzzos3	221	10	CDV	CDV	NNP
cord-003614-63rzzos3	221	11	-	-	HYPH
cord-003614-63rzzos3	221	12	induced	induce	VBN
cord-003614-63rzzos3	221	13	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	221	14	lesions	lesion	NNS
cord-003614-63rzzos3	221	15	most	most	RBS
cord-003614-63rzzos3	221	16	likely	likely	RB
cord-003614-63rzzos3	221	17	contribute	contribute	VBP
cord-003614-63rzzos3	221	18	to	to	IN
cord-003614-63rzzos3	221	19	viral	viral	JJ
cord-003614-63rzzos3	221	20	elimination	elimination	NN
cord-003614-63rzzos3	221	21	and	and	CC
cord-003614-63rzzos3	221	22	might	may	MD
cord-003614-63rzzos3	221	23	modulate	modulate	VB
cord-003614-63rzzos3	221	24	the	the	DT
cord-003614-63rzzos3	221	25	canine	canine	JJ
cord-003614-63rzzos3	221	26	immune	immune	NN
cord-003614-63rzzos3	221	27	system	system	NN
cord-003614-63rzzos3	221	28	.	.	.
cord-003614-63rzzos3	222	1	PKR	PKR	NNP
cord-003614-63rzzos3	222	2	can	can	MD
cord-003614-63rzzos3	222	3	be	be	VB
cord-003614-63rzzos3	222	4	activated	activate	VBN
cord-003614-63rzzos3	222	5	by	by	IN
cord-003614-63rzzos3	222	6	double	double	RB
cord-003614-63rzzos3	222	7	-	-	HYPH
cord-003614-63rzzos3	222	8	stranded	strand	VBN
cord-003614-63rzzos3	222	9	RNA	RNA	NNP
cord-003614-63rzzos3	222	10	and	and	CC
cord-003614-63rzzos3	222	11	ISGylation	ISGylation	NNP
cord-003614-63rzzos3	222	12	,	,	,
cord-003614-63rzzos3	222	13	which	which	WDT
cord-003614-63rzzos3	222	14	results	result	VBZ
cord-003614-63rzzos3	222	15	in	in	IN
cord-003614-63rzzos3	222	16	autophosphorylation	autophosphorylation	NN
cord-003614-63rzzos3	222	17	and	and	CC
cord-003614-63rzzos3	222	18	subsequently	subsequently	RB
cord-003614-63rzzos3	222	19	in	in	IN
cord-003614-63rzzos3	222	20	phosphorylation	phosphorylation	NN
cord-003614-63rzzos3	222	21	of	of	IN
cord-003614-63rzzos3	222	22	the	the	DT
cord-003614-63rzzos3	222	23	eukaryotic	eukaryotic	JJ
cord-003614-63rzzos3	222	24	translation	translation	NN
cord-003614-63rzzos3	222	25	initiation	initiation	NN
cord-003614-63rzzos3	222	26	factor	factor	NN
cord-003614-63rzzos3	222	27	2	2	CD
cord-003614-63rzzos3	222	28	alpha	alpha	NN
cord-003614-63rzzos3	222	29	(	(	-LRB-
cord-003614-63rzzos3	222	30	eIF2α	eIF2α	NNP
cord-003614-63rzzos3	222	31	)	)	-RRB-
cord-003614-63rzzos3	222	32	,	,	,
cord-003614-63rzzos3	222	33	thereby	thereby	RB
cord-003614-63rzzos3	222	34	down	down	RB
cord-003614-63rzzos3	222	35	-	-	HYPH
cord-003614-63rzzos3	222	36	regulating	regulate	VBG
cord-003614-63rzzos3	222	37	cellular	cellular	JJ
cord-003614-63rzzos3	222	38	and	and	CC
cord-003614-63rzzos3	222	39	viral	viral	JJ
cord-003614-63rzzos3	222	40	protein	protein	NN
cord-003614-63rzzos3	222	41	synthesis	synthesis	NN
cord-003614-63rzzos3	222	42	[	[	-LRB-
cord-003614-63rzzos3	222	43	81	81	CD
cord-003614-63rzzos3	222	44	]	]	-RRB-
cord-003614-63rzzos3	222	45	[	[	-LRB-
cord-003614-63rzzos3	222	46	82	82	CD
cord-003614-63rzzos3	222	47	]	]	-RRB-
cord-003614-63rzzos3	223	1	[	[	-LRB-
cord-003614-63rzzos3	223	2	83	83	CD
cord-003614-63rzzos3	223	3	]	]	-RRB-
cord-003614-63rzzos3	223	4	[	[	-LRB-
cord-003614-63rzzos3	223	5	84	84	CD
cord-003614-63rzzos3	223	6	]	]	-RRB-
cord-003614-63rzzos3	223	7	.	.	.
cord-003614-63rzzos3	224	1	In	in	IN
cord-003614-63rzzos3	224	2	addition	addition	NN
cord-003614-63rzzos3	224	3	,	,	,
cord-003614-63rzzos3	224	4	the	the	DT
cord-003614-63rzzos3	224	5	activation	activation	NN
cord-003614-63rzzos3	224	6	of	of	IN
cord-003614-63rzzos3	224	7	this	this	DT
cord-003614-63rzzos3	224	8	constitutively	constitutively	RB
cord-003614-63rzzos3	224	9	expressed	express	VBN
cord-003614-63rzzos3	224	10	virus	virus	NN
cord-003614-63rzzos3	224	11	sensor	sensor	NN
cord-003614-63rzzos3	224	12	protein	protein	NN
cord-003614-63rzzos3	224	13	can	can	MD
cord-003614-63rzzos3	224	14	induce	induce	VB
cord-003614-63rzzos3	224	15	apoptosis	apoptosis	NN
cord-003614-63rzzos3	224	16	,	,	,
cord-003614-63rzzos3	224	17	thus	thus	RB
cord-003614-63rzzos3	224	18	ensuring	ensure	VBG
cord-003614-63rzzos3	224	19	the	the	DT
cord-003614-63rzzos3	224	20	eradication	eradication	NN
cord-003614-63rzzos3	224	21	of	of	IN
cord-003614-63rzzos3	224	22	infected	infected	JJ
cord-003614-63rzzos3	224	23	cells	cell	NNS
cord-003614-63rzzos3	224	24	from	from	IN
cord-003614-63rzzos3	224	25	the	the	DT
cord-003614-63rzzos3	224	26	tissue	tissue	NN
cord-003614-63rzzos3	224	27	[	[	-LRB-
cord-003614-63rzzos3	224	28	85	85	CD
cord-003614-63rzzos3	224	29	,	,	,
cord-003614-63rzzos3	224	30	86	86	CD
cord-003614-63rzzos3	224	31	]	]	-RRB-
cord-003614-63rzzos3	224	32	.	.	.
cord-003614-63rzzos3	225	1	The	the	DT
cord-003614-63rzzos3	225	2	present	present	JJ
cord-003614-63rzzos3	225	3	study	study	NN
cord-003614-63rzzos3	225	4	demonstrated	demonstrate	VBD
cord-003614-63rzzos3	225	5	a	a	DT
cord-003614-63rzzos3	225	6	strong	strong	JJ
cord-003614-63rzzos3	225	7	increase	increase	NN
cord-003614-63rzzos3	225	8	in	in	IN
cord-003614-63rzzos3	225	9	the	the	DT
cord-003614-63rzzos3	225	10	expression	expression	NN
cord-003614-63rzzos3	225	11	of	of	IN
cord-003614-63rzzos3	225	12	phosphorylated	phosphorylated	JJ
cord-003614-63rzzos3	225	13	,	,	,
cord-003614-63rzzos3	225	14	hence	hence	RB
cord-003614-63rzzos3	225	15	activated	activate	VBD
cord-003614-63rzzos3	225	16	PKR	PKR	NNP
cord-003614-63rzzos3	225	17	in	in	IN
cord-003614-63rzzos3	225	18	the	the	DT
cord-003614-63rzzos3	225	19	CDV	CDV	NNP
cord-003614-63rzzos3	225	20	-	-	HYPH
cord-003614-63rzzos3	225	21	infected	infect	VBN
cord-003614-63rzzos3	225	22	cerebellum	cerebellum	NN
cord-003614-63rzzos3	225	23	.	.	.
cord-003614-63rzzos3	226	1	This	this	DT
cord-003614-63rzzos3	226	2	protein	protein	NN
cord-003614-63rzzos3	226	3	was	be	VBD
cord-003614-63rzzos3	226	4	detected	detect	VBN
cord-003614-63rzzos3	226	5	in	in	IN
cord-003614-63rzzos3	226	6	neurons	neuron	NNS
cord-003614-63rzzos3	226	7	,	,	,
cord-003614-63rzzos3	226	8	intralesional	intralesional	JJ
cord-003614-63rzzos3	226	9	astrocytes	astrocyte	NNS
cord-003614-63rzzos3	226	10	and	and	CC
cord-003614-63rzzos3	226	11	oligodendrocytes	oligodendrocyte	NNS
cord-003614-63rzzos3	226	12	as	as	RB
cord-003614-63rzzos3	226	13	well	well	RB
cord-003614-63rzzos3	226	14	as	as	IN
cord-003614-63rzzos3	226	15	perivascular	perivascular	JJ
cord-003614-63rzzos3	226	16	lymphocytes	lymphocyte	NNS
cord-003614-63rzzos3	226	17	but	but	CC
cord-003614-63rzzos3	226	18	not	not	RB
cord-003614-63rzzos3	226	19	in	in	IN
cord-003614-63rzzos3	226	20	microglia	microglia	NNS
cord-003614-63rzzos3	226	21	/	/	SYM
cord-003614-63rzzos3	226	22	macrophages	macrophage	NNS
cord-003614-63rzzos3	226	23	.	.	.
cord-003614-63rzzos3	227	1	Similarly	similarly	RB
cord-003614-63rzzos3	227	2	,	,	,
cord-003614-63rzzos3	227	3	TMEV	TMEV	NNP
cord-003614-63rzzos3	227	4	-	-	HYPH
cord-003614-63rzzos3	227	5	infected	infect	VBN
cord-003614-63rzzos3	227	6	mice	mouse	NNS
cord-003614-63rzzos3	227	7	showed	show	VBD
cord-003614-63rzzos3	227	8	a	a	DT
cord-003614-63rzzos3	227	9	strong	strong	JJ
cord-003614-63rzzos3	227	10	expression	expression	NN
cord-003614-63rzzos3	227	11	of	of	IN
cord-003614-63rzzos3	227	12	activated	activate	VBN
cord-003614-63rzzos3	227	13	PKR	PKR	NNP
cord-003614-63rzzos3	227	14	proteins	protein	NNS
cord-003614-63rzzos3	227	15	in	in	IN
cord-003614-63rzzos3	227	16	spinal	spinal	JJ
cord-003614-63rzzos3	227	17	cord	cord	NN
cord-003614-63rzzos3	227	18	white	white	JJ
cord-003614-63rzzos3	227	19	matter	matter	NN
cord-003614-63rzzos3	227	20	lesions	lesion	NNS
cord-003614-63rzzos3	227	21	[	[	-LRB-
cord-003614-63rzzos3	227	22	62	62	CD
cord-003614-63rzzos3	227	23	]	]	-RRB-
cord-003614-63rzzos3	227	24	.	.	.
cord-003614-63rzzos3	228	1	Nevertheless	nevertheless	RB
cord-003614-63rzzos3	228	2	,	,	,
cord-003614-63rzzos3	228	3	these	these	DT
cord-003614-63rzzos3	228	4	proteins	protein	NNS
cord-003614-63rzzos3	228	5	were	be	VBD
cord-003614-63rzzos3	228	6	predominantly	predominantly	RB
cord-003614-63rzzos3	228	7	expressed	express	VBN
cord-003614-63rzzos3	228	8	by	by	IN
cord-003614-63rzzos3	228	9	intralesional	intralesional	NNP
cord-003614-63rzzos3	228	10	gitter	gitter	NNP
cord-003614-63rzzos3	228	11	cells	cell	NNS
cord-003614-63rzzos3	228	12	and	and	CC
cord-003614-63rzzos3	228	13	to	to	IN
cord-003614-63rzzos3	228	14	a	a	DT
cord-003614-63rzzos3	228	15	lesser	less	JJR
cord-003614-63rzzos3	228	16	extent	extent	NN
cord-003614-63rzzos3	228	17	by	by	IN
cord-003614-63rzzos3	228	18	perivascular	perivascular	JJ
cord-003614-63rzzos3	228	19	immune	immune	JJ
cord-003614-63rzzos3	228	20	cells	cell	NNS
cord-003614-63rzzos3	228	21	,	,	,
cord-003614-63rzzos3	228	22	oligodendrocytes	oligodendrocyte	NNS
cord-003614-63rzzos3	228	23	and	and	CC
cord-003614-63rzzos3	228	24	neurons	neuron	NNS
cord-003614-63rzzos3	228	25	but	but	CC
cord-003614-63rzzos3	228	26	not	not	RB
cord-003614-63rzzos3	228	27	by	by	IN
cord-003614-63rzzos3	228	28	astrocytes	astrocyte	NNS
cord-003614-63rzzos3	228	29	in	in	IN
cord-003614-63rzzos3	228	30	TMEV	TMEV	NNP
cord-003614-63rzzos3	228	31	-	-	HYPH
cord-003614-63rzzos3	228	32	infected	infect	VBN
cord-003614-63rzzos3	228	33	mice	mouse	NNS
cord-003614-63rzzos3	228	34	.	.	.
cord-003614-63rzzos3	229	1	Similarly	similarly	RB
cord-003614-63rzzos3	229	2	,	,	,
cord-003614-63rzzos3	229	3	in	in	IN
cord-003614-63rzzos3	229	4	mice	mouse	NNS
cord-003614-63rzzos3	229	5	suffering	suffer	VBG
cord-003614-63rzzos3	229	6	from	from	IN
cord-003614-63rzzos3	229	7	experimental	experimental	JJ
cord-003614-63rzzos3	229	8	allergic	allergic	JJ
cord-003614-63rzzos3	229	9	encephalomyelitis	encephalomyelitis	NN
cord-003614-63rzzos3	229	10	,	,	,
cord-003614-63rzzos3	229	11	another	another	DT
cord-003614-63rzzos3	229	12	mouse	mouse	NN
cord-003614-63rzzos3	229	13	model	model	NN
cord-003614-63rzzos3	229	14	of	of	IN
cord-003614-63rzzos3	229	15	human	human	JJ
cord-003614-63rzzos3	229	16	MS	MS	NNP
cord-003614-63rzzos3	229	17	,	,	,
cord-003614-63rzzos3	229	18	activated	activate	VBD
cord-003614-63rzzos3	229	19	PKR	PKR	NNP
cord-003614-63rzzos3	229	20	proteins	protein	NNS
cord-003614-63rzzos3	229	21	were	be	VBD
cord-003614-63rzzos3	229	22	found	find	VBN
cord-003614-63rzzos3	229	23	in	in	IN
cord-003614-63rzzos3	229	24	oligodendrocytes	oligodendrocyte	NNS
cord-003614-63rzzos3	229	25	and	and	CC
cord-003614-63rzzos3	229	26	neurons	neuron	NNS
cord-003614-63rzzos3	229	27	as	as	RB
cord-003614-63rzzos3	229	28	well	well	RB
cord-003614-63rzzos3	229	29	as	as	IN
cord-003614-63rzzos3	229	30	in	in	IN
cord-003614-63rzzos3	229	31	intralesional	intralesional	JJ
cord-003614-63rzzos3	229	32	T	t	NN
cord-003614-63rzzos3	229	33	cells	cell	NNS
cord-003614-63rzzos3	229	34	and	and	CC
cord-003614-63rzzos3	229	35	macrophages	macrophage	NNS
cord-003614-63rzzos3	229	36	[	[	-LRB-
cord-003614-63rzzos3	229	37	87	87	CD
cord-003614-63rzzos3	229	38	]	]	-RRB-
cord-003614-63rzzos3	229	39	.	.	.
cord-003614-63rzzos3	230	1	These	these	DT
cord-003614-63rzzos3	230	2	observations	observation	NNS
cord-003614-63rzzos3	230	3	suggest	suggest	VBP
cord-003614-63rzzos3	230	4	a	a	DT
cord-003614-63rzzos3	230	5	so	so	RB
cord-003614-63rzzos3	230	6	far	far	RB
cord-003614-63rzzos3	230	7	undescribed	undescribed	JJ
cord-003614-63rzzos3	230	8	species	species	NN
cord-003614-63rzzos3	230	9	-	-	HYPH
cord-003614-63rzzos3	230	10	specific	specific	JJ
cord-003614-63rzzos3	230	11	difference	difference	NN
cord-003614-63rzzos3	230	12	in	in	IN
cord-003614-63rzzos3	230	13	PKR	PKR	NNP
cord-003614-63rzzos3	230	14	expression	expression	NN
cord-003614-63rzzos3	230	15	and/or	and/or	CC
cord-003614-63rzzos3	230	16	activation	activation	NN
cord-003614-63rzzos3	230	17	of	of	IN
cord-003614-63rzzos3	230	18	murine	murine	JJ
cord-003614-63rzzos3	230	19	and	and	CC
cord-003614-63rzzos3	230	20	canine	canine	JJ
cord-003614-63rzzos3	230	21	astrocytes	astrocyte	NNS
cord-003614-63rzzos3	230	22	and	and	CC
cord-003614-63rzzos3	230	23	microglia	microglia	NNS
cord-003614-63rzzos3	230	24	/	/	SYM
cord-003614-63rzzos3	230	25	macrophages	macrophage	NNS
cord-003614-63rzzos3	230	26	.	.	.
cord-003614-63rzzos3	231	1	Similar	similar	JJ
cord-003614-63rzzos3	231	2	to	to	IN
cord-003614-63rzzos3	231	3	PKR	PKR	NNP
cord-003614-63rzzos3	231	4	,	,	,
cord-003614-63rzzos3	231	5	OAS	OAS	NNP
cord-003614-63rzzos3	231	6	proteins	protein	NNS
cord-003614-63rzzos3	231	7	are	be	VBP
cord-003614-63rzzos3	231	8	constitutively	constitutively	RB
cord-003614-63rzzos3	231	9	expressed	express	VBN
cord-003614-63rzzos3	231	10	in	in	IN
cord-003614-63rzzos3	231	11	many	many	JJ
cord-003614-63rzzos3	231	12	tissues	tissue	NNS
cord-003614-63rzzos3	231	13	(	(	-LRB-
cord-003614-63rzzos3	231	14	spleen	spleen	NN
cord-003614-63rzzos3	231	15	,	,	,
cord-003614-63rzzos3	231	16	lung	lung	NN
cord-003614-63rzzos3	231	17	,	,	,
cord-003614-63rzzos3	231	18	liver	liver	NN
cord-003614-63rzzos3	231	19	,	,	,
cord-003614-63rzzos3	231	20	thymus	thymus	NN
cord-003614-63rzzos3	231	21	,	,	,
cord-003614-63rzzos3	231	22	small	small	JJ
cord-003614-63rzzos3	231	23	intestine	intestine	NN
cord-003614-63rzzos3	231	24	,	,	,
cord-003614-63rzzos3	231	25	brain	brain	NN
cord-003614-63rzzos3	231	26	)	)	-RRB-
cord-003614-63rzzos3	231	27	and	and	CC
cord-003614-63rzzos3	231	28	bind	bind	VB
cord-003614-63rzzos3	231	29	double	double	RB
cord-003614-63rzzos3	231	30	-	-	HYPH
cord-003614-63rzzos3	231	31	stranded	strand	VBN
cord-003614-63rzzos3	231	32	RNA	RNA	NNP
cord-003614-63rzzos3	231	33	resulting	result	VBG
cord-003614-63rzzos3	231	34	in	in	IN
cord-003614-63rzzos3	231	35	their	-PRON-	PRP$
cord-003614-63rzzos3	231	36	activation	activation	NN
cord-003614-63rzzos3	231	37	[	[	-LRB-
cord-003614-63rzzos3	231	38	88	88	CD
cord-003614-63rzzos3	231	39	]	]	-RRB-
cord-003614-63rzzos3	231	40	[	[	-LRB-
cord-003614-63rzzos3	231	41	89	89	CD
cord-003614-63rzzos3	231	42	]	]	-RRB-
cord-003614-63rzzos3	231	43	[	[	-LRB-
cord-003614-63rzzos3	231	44	90	90	CD
cord-003614-63rzzos3	231	45	]	]	-RRB-
cord-003614-63rzzos3	231	46	.	.	.
cord-003614-63rzzos3	232	1	Activated	activate	VBN
cord-003614-63rzzos3	232	2	OAS	OAS	NNP
cord-003614-63rzzos3	232	3	proteins	protein	NNS
cord-003614-63rzzos3	232	4	then	then	RB
cord-003614-63rzzos3	232	5	induce	induce	VBP
cord-003614-63rzzos3	232	6	the	the	DT
cord-003614-63rzzos3	232	7	formation	formation	NN
cord-003614-63rzzos3	232	8	of	of	IN
cord-003614-63rzzos3	232	9	2	2	CD
cord-003614-63rzzos3	232	10	-5	-5	CD
cord-003614-63rzzos3	232	11	-oligoadenylates	-oligoadenylate	NNS
cord-003614-63rzzos3	232	12	from	from	IN
cord-003614-63rzzos3	232	13	ATP	ATP	NNP
cord-003614-63rzzos3	232	14	molecules	molecule	NNS
cord-003614-63rzzos3	232	15	,	,	,
cord-003614-63rzzos3	232	16	which	which	WDT
cord-003614-63rzzos3	232	17	trigger	trigger	VBP
cord-003614-63rzzos3	232	18	the	the	DT
cord-003614-63rzzos3	232	19	ubiquitously	ubiquitously	RB
cord-003614-63rzzos3	232	20	expressed	express	VBN
cord-003614-63rzzos3	232	21	endoribonuclease	endoribonuclease	NN
cord-003614-63rzzos3	232	22	RNase	RNase	NNP
cord-003614-63rzzos3	232	23	L	L	NNP
cord-003614-63rzzos3	232	24	[	[	-LRB-
cord-003614-63rzzos3	232	25	91	91	CD
cord-003614-63rzzos3	232	26	]	]	-RRB-
cord-003614-63rzzos3	232	27	.	.	.
cord-003614-63rzzos3	233	1	This	this	DT
cord-003614-63rzzos3	233	2	enzyme	enzyme	NN
cord-003614-63rzzos3	233	3	can	can	MD
cord-003614-63rzzos3	233	4	degrade	degrade	VB
cord-003614-63rzzos3	233	5	cellular	cellular	JJ
cord-003614-63rzzos3	233	6	and	and	CC
cord-003614-63rzzos3	233	7	viral	viral	JJ
cord-003614-63rzzos3	233	8	RNA	RNA	NNP
cord-003614-63rzzos3	233	9	and	and	CC
cord-003614-63rzzos3	233	10	thereby	thereby	RB
cord-003614-63rzzos3	233	11	inhibit	inhibit	VB
cord-003614-63rzzos3	233	12	viral	viral	JJ
cord-003614-63rzzos3	233	13	protein	protein	NN
cord-003614-63rzzos3	233	14	synthesis	synthesis	NN
cord-003614-63rzzos3	233	15	[	[	-LRB-
cord-003614-63rzzos3	233	16	91	91	CD
cord-003614-63rzzos3	233	17	]	]	-RRB-
cord-003614-63rzzos3	233	18	[	[	-LRB-
cord-003614-63rzzos3	233	19	92	92	CD
cord-003614-63rzzos3	233	20	]	]	-RRB-
cord-003614-63rzzos3	233	21	[	[	-LRB-
cord-003614-63rzzos3	233	22	93	93	CD
cord-003614-63rzzos3	233	23	]	]	-RRB-
cord-003614-63rzzos3	233	24	.	.	.
cord-003614-63rzzos3	234	1	The	the	DT
cord-003614-63rzzos3	234	2	production	production	NN
cord-003614-63rzzos3	234	3	of	of	IN
cord-003614-63rzzos3	234	4	small	small	JJ
cord-003614-63rzzos3	234	5	RNA	RNA	NNP
cord-003614-63rzzos3	234	6	cleavage	cleavage	NN
cord-003614-63rzzos3	234	7	products	product	NNS
cord-003614-63rzzos3	234	8	by	by	IN
cord-003614-63rzzos3	234	9	RNase	RNase	NNP
cord-003614-63rzzos3	234	10	L	L	NNP
cord-003614-63rzzos3	234	11	again	again	RB
cord-003614-63rzzos3	234	12	initiates	initiate	VBZ
cord-003614-63rzzos3	234	13	IFN	IFN	NNP
cord-003614-63rzzos3	234	14	-	-	HYPH
cord-003614-63rzzos3	234	15	I	I	NNP
cord-003614-63rzzos3	234	16	production	production	NN
cord-003614-63rzzos3	234	17	,	,	,
cord-003614-63rzzos3	234	18	creating	create	VBG
cord-003614-63rzzos3	234	19	a	a	DT
cord-003614-63rzzos3	234	20	positive	positive	JJ
cord-003614-63rzzos3	234	21	feedback	feedback	NN
cord-003614-63rzzos3	234	22	mechanism	mechanism	NN
cord-003614-63rzzos3	234	23	in	in	IN
cord-003614-63rzzos3	234	24	antiviral	antiviral	JJ
cord-003614-63rzzos3	234	25	defense	defense	NN
cord-003614-63rzzos3	234	26	[	[	-LRB-
cord-003614-63rzzos3	234	27	93	93	CD
cord-003614-63rzzos3	234	28	,	,	,
cord-003614-63rzzos3	234	29	94	94	CD
cord-003614-63rzzos3	234	30	]	]	-RRB-
cord-003614-63rzzos3	234	31	.	.	.
cord-003614-63rzzos3	235	1	RNase	RNase	NNP
cord-003614-63rzzos3	235	2	L	L	NNP
cord-003614-63rzzos3	235	3	has	have	VBZ
cord-003614-63rzzos3	235	4	also	also	RB
cord-003614-63rzzos3	235	5	been	be	VBN
cord-003614-63rzzos3	235	6	described	describe	VBN
cord-003614-63rzzos3	235	7	as	as	IN
cord-003614-63rzzos3	235	8	a	a	DT
cord-003614-63rzzos3	235	9	potent	potent	JJ
cord-003614-63rzzos3	235	10	inducer	inducer	NN
cord-003614-63rzzos3	235	11	of	of	IN
cord-003614-63rzzos3	235	12	apoptosis	apoptosis	NN
cord-003614-63rzzos3	235	13	in	in	IN
cord-003614-63rzzos3	235	14	fibroblasts	fibroblast	NNS
cord-003614-63rzzos3	235	15	[	[	-LRB-
cord-003614-63rzzos3	235	16	95	95	CD
cord-003614-63rzzos3	235	17	]	]	-RRB-
cord-003614-63rzzos3	235	18	.	.	.
cord-003614-63rzzos3	236	1	In	in	IN
cord-003614-63rzzos3	236	2	addition	addition	NN
cord-003614-63rzzos3	236	3	,	,	,
cord-003614-63rzzos3	236	4	Kristiansen	Kristiansen	NNP
cord-003614-63rzzos3	236	5	et	et	NNP
cord-003614-63rzzos3	236	6	al	al	NNP
cord-003614-63rzzos3	236	7	.	.	.
cord-003614-63rzzos3	237	1	(	(	-LRB-
cord-003614-63rzzos3	237	2	2010	2010	CD
cord-003614-63rzzos3	237	3	)	)	-RRB-
cord-003614-63rzzos3	237	4	suggested	suggest	VBD
cord-003614-63rzzos3	237	5	that	that	IN
cord-003614-63rzzos3	237	6	OAS	OAS	NNP
cord-003614-63rzzos3	237	7	proteins	protein	NNS
cord-003614-63rzzos3	237	8	produced	produce	VBN
cord-003614-63rzzos3	237	9	by	by	IN
cord-003614-63rzzos3	237	10	virus	virus	NN
cord-003614-63rzzos3	237	11	-	-	HYPH
cord-003614-63rzzos3	237	12	infected	infect	VBN
cord-003614-63rzzos3	237	13	cells	cell	NNS
cord-003614-63rzzos3	237	14	can	can	MD
cord-003614-63rzzos3	237	15	be	be	VB
cord-003614-63rzzos3	237	16	released	release	VBN
cord-003614-63rzzos3	237	17	into	into	IN
cord-003614-63rzzos3	237	18	the	the	DT
cord-003614-63rzzos3	237	19	extracellular	extracellular	JJ
cord-003614-63rzzos3	237	20	space	space	NN
cord-003614-63rzzos3	237	21	,	,	,
cord-003614-63rzzos3	237	22	where	where	WRB
cord-003614-63rzzos3	237	23	it	-PRON-	PRP
cord-003614-63rzzos3	237	24	acts	act	VBZ
cord-003614-63rzzos3	237	25	as	as	IN
cord-003614-63rzzos3	237	26	an	an	DT
cord-003614-63rzzos3	237	27	RNase	RNase	NNP
cord-003614-63rzzos3	237	28	L	l	NN
cord-003614-63rzzos3	237	29	-	-	HYPH
cord-003614-63rzzos3	237	30	independent	independent	JJ
cord-003614-63rzzos3	237	31	paracrine	paracrine	JJ
cord-003614-63rzzos3	237	32	antiviral	antiviral	JJ
cord-003614-63rzzos3	237	33	agent	agent	NN
cord-003614-63rzzos3	237	34	to	to	TO
cord-003614-63rzzos3	237	35	protect	protect	VB
cord-003614-63rzzos3	237	36	neighboring	neighboring	NN
cord-003614-63rzzos3	237	37	cells	cell	NNS
cord-003614-63rzzos3	237	38	from	from	IN
cord-003614-63rzzos3	237	39	infection	infection	NN
cord-003614-63rzzos3	237	40	[	[	-LRB-
cord-003614-63rzzos3	237	41	96	96	CD
cord-003614-63rzzos3	237	42	]	]	-RRB-
cord-003614-63rzzos3	237	43	.	.	.
cord-003614-63rzzos3	238	1	The	the	DT
cord-003614-63rzzos3	238	2	present	present	JJ
cord-003614-63rzzos3	238	3	study	study	NN
cord-003614-63rzzos3	238	4	revealed	reveal	VBD
cord-003614-63rzzos3	238	5	a	a	DT
cord-003614-63rzzos3	238	6	strong	strong	JJ
cord-003614-63rzzos3	238	7	increase	increase	NN
cord-003614-63rzzos3	238	8	in	in	IN
cord-003614-63rzzos3	238	9	OAS	OAS	NNP
cord-003614-63rzzos3	238	10	gene	gene	NN
cord-003614-63rzzos3	238	11	and	and	CC
cord-003614-63rzzos3	238	12	protein	protein	NN
cord-003614-63rzzos3	238	13	expression	expression	NN
cord-003614-63rzzos3	238	14	in	in	IN
cord-003614-63rzzos3	238	15	acute	acute	JJ
cord-003614-63rzzos3	238	16	,	,	,
cord-003614-63rzzos3	238	17	subacute	subacute	JJ
cord-003614-63rzzos3	238	18	and	and	CC
cord-003614-63rzzos3	238	19	chronic	chronic	JJ
cord-003614-63rzzos3	238	20	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	238	21	lesions	lesion	NNS
cord-003614-63rzzos3	238	22	,	,	,
cord-003614-63rzzos3	238	23	which	which	WDT
cord-003614-63rzzos3	238	24	most	most	RBS
cord-003614-63rzzos3	238	25	likely	likely	RB
cord-003614-63rzzos3	238	26	contributes	contribute	VBZ
cord-003614-63rzzos3	238	27	to	to	IN
cord-003614-63rzzos3	238	28	the	the	DT
cord-003614-63rzzos3	238	29	restriction	restriction	NN
cord-003614-63rzzos3	238	30	of	of	IN
cord-003614-63rzzos3	238	31	viral	viral	JJ
cord-003614-63rzzos3	238	32	replication	replication	NN
cord-003614-63rzzos3	238	33	.	.	.
cord-003614-63rzzos3	239	1	OAS	OAS	NNP
cord-003614-63rzzos3	239	2	proteins	protein	NNS
cord-003614-63rzzos3	239	3	were	be	VBD
cord-003614-63rzzos3	239	4	detected	detect	VBN
cord-003614-63rzzos3	239	5	in	in	IN
cord-003614-63rzzos3	239	6	neurons	neuron	NNS
cord-003614-63rzzos3	239	7	and	and	CC
cord-003614-63rzzos3	239	8	endothelial	endothelial	JJ
cord-003614-63rzzos3	239	9	cells	cell	NNS
cord-003614-63rzzos3	239	10	as	as	RB
cord-003614-63rzzos3	239	11	well	well	RB
cord-003614-63rzzos3	239	12	as	as	IN
cord-003614-63rzzos3	239	13	in	in	IN
cord-003614-63rzzos3	239	14	intralesional	intralesional	JJ
cord-003614-63rzzos3	239	15	glial	glial	JJ
cord-003614-63rzzos3	239	16	cells	cell	NNS
cord-003614-63rzzos3	239	17	and	and	CC
cord-003614-63rzzos3	239	18	perivascular	perivascular	JJ
cord-003614-63rzzos3	239	19	inflammatory	inflammatory	JJ
cord-003614-63rzzos3	239	20	cells	cell	NNS
cord-003614-63rzzos3	239	21	.	.	.
cord-003614-63rzzos3	240	1	Previous	previous	JJ
cord-003614-63rzzos3	240	2	studies	study	NNS
cord-003614-63rzzos3	240	3	demonstrated	demonstrate	VBD
cord-003614-63rzzos3	240	4	that	that	IN
cord-003614-63rzzos3	240	5	the	the	DT
cord-003614-63rzzos3	240	6	OAS	OAS	NNP
cord-003614-63rzzos3	240	7	-	-	HYPH
cord-003614-63rzzos3	240	8	RNase	RNase	NNP
cord-003614-63rzzos3	240	9	L	L	NNP
cord-003614-63rzzos3	240	10	pathway	pathway	NN
cord-003614-63rzzos3	240	11	is	be	VBZ
cord-003614-63rzzos3	240	12	particularly	particularly	RB
cord-003614-63rzzos3	240	13	important	important	JJ
cord-003614-63rzzos3	240	14	in	in	IN
cord-003614-63rzzos3	240	15	murine	murine	JJ
cord-003614-63rzzos3	240	16	macrophages	macrophage	NNS
cord-003614-63rzzos3	240	17	and	and	CC
cord-003614-63rzzos3	240	18	inhibits	inhibit	VBZ
cord-003614-63rzzos3	240	19	the	the	DT
cord-003614-63rzzos3	240	20	replication	replication	NN
cord-003614-63rzzos3	240	21	of	of	IN
cord-003614-63rzzos3	240	22	Picornaviridae	Picornaviridae	NNP
cord-003614-63rzzos3	240	23	including	include	VBG
cord-003614-63rzzos3	240	24	TMEV	TMEV	NNP
cord-003614-63rzzos3	241	1	[	[	-LRB-
cord-003614-63rzzos3	241	2	93	93	CD
cord-003614-63rzzos3	241	3	,	,	,
cord-003614-63rzzos3	241	4	[	[	-LRB-
cord-003614-63rzzos3	241	5	97	97	CD
cord-003614-63rzzos3	241	6	]	]	-RRB-
cord-003614-63rzzos3	241	7	[	[	-LRB-
cord-003614-63rzzos3	241	8	98	98	CD
cord-003614-63rzzos3	241	9	]	]	-RRB-
cord-003614-63rzzos3	242	1	[	[	-LRB-
cord-003614-63rzzos3	242	2	99	99	CD
cord-003614-63rzzos3	242	3	]	]	-RRB-
cord-003614-63rzzos3	242	4	[	[	-LRB-
cord-003614-63rzzos3	242	5	100	100	CD
cord-003614-63rzzos3	242	6	]	]	-RRB-
cord-003614-63rzzos3	242	7	[	[	-LRB-
cord-003614-63rzzos3	242	8	101	101	CD
cord-003614-63rzzos3	242	9	]	]	-RRB-
cord-003614-63rzzos3	242	10	.	.	.
cord-003614-63rzzos3	243	1	Interestingly	interestingly	RB
cord-003614-63rzzos3	243	2	,	,	,
cord-003614-63rzzos3	243	3	the	the	DT
cord-003614-63rzzos3	243	4	OAS	OAS	NNP
cord-003614-63rzzos3	243	5	activity	activity	NN
cord-003614-63rzzos3	243	6	in	in	IN
cord-003614-63rzzos3	243	7	canine	canine	JJ
cord-003614-63rzzos3	243	8	serum	serum	NN
cord-003614-63rzzos3	243	9	is	be	VBZ
cord-003614-63rzzos3	243	10	10-to	10-to	CD
cord-003614-63rzzos3	243	11	100-fold	100-fold	CD
cord-003614-63rzzos3	243	12	higher	high	JJR
cord-003614-63rzzos3	243	13	than	than	IN
cord-003614-63rzzos3	243	14	in	in	IN
cord-003614-63rzzos3	243	15	cats	cat	NNS
cord-003614-63rzzos3	243	16	,	,	,
cord-003614-63rzzos3	243	17	rabbits	rabbit	NNS
cord-003614-63rzzos3	243	18	and	and	CC
cord-003614-63rzzos3	243	19	guinea	guinea	NN
cord-003614-63rzzos3	243	20	pigs	pig	NNS
cord-003614-63rzzos3	243	21	,	,	,
cord-003614-63rzzos3	243	22	indicating	indicate	VBG
cord-003614-63rzzos3	243	23	a	a	DT
cord-003614-63rzzos3	243	24	prominent	prominent	JJ
cord-003614-63rzzos3	243	25	role	role	NN
cord-003614-63rzzos3	243	26	of	of	IN
cord-003614-63rzzos3	243	27	OAS	OAS	NNP
cord-003614-63rzzos3	243	28	proteins	protein	NNS
cord-003614-63rzzos3	243	29	in	in	IN
cord-003614-63rzzos3	243	30	the	the	DT
cord-003614-63rzzos3	243	31	canine	canine	JJ
cord-003614-63rzzos3	243	32	humoral	humoral	JJ
cord-003614-63rzzos3	243	33	immune	immune	JJ
cord-003614-63rzzos3	243	34	system	system	NN
cord-003614-63rzzos3	243	35	[	[	-LRB-
cord-003614-63rzzos3	243	36	46	46	CD
cord-003614-63rzzos3	243	37	]	]	-RRB-
cord-003614-63rzzos3	243	38	.	.	.
cord-003614-63rzzos3	244	1	However	however	RB
cord-003614-63rzzos3	244	2	,	,	,
cord-003614-63rzzos3	244	3	the	the	DT
cord-003614-63rzzos3	244	4	exact	exact	JJ
cord-003614-63rzzos3	244	5	role	role	NN
cord-003614-63rzzos3	244	6	of	of	IN
cord-003614-63rzzos3	244	7	RNase	RNase	NNP
cord-003614-63rzzos3	244	8	L	l	NN
cord-003614-63rzzos3	244	9	-	-	HYPH
cord-003614-63rzzos3	244	10	dependent	dependent	JJ
cord-003614-63rzzos3	244	11	and	and	CC
cord-003614-63rzzos3	244	12	independent	independent	JJ
cord-003614-63rzzos3	244	13	functions	function	NNS
cord-003614-63rzzos3	244	14	of	of	IN
cord-003614-63rzzos3	244	15	OAS	OAS	NNP
cord-003614-63rzzos3	244	16	proteins	protein	NNS
cord-003614-63rzzos3	244	17	in	in	IN
cord-003614-63rzzos3	244	18	the	the	DT
cord-003614-63rzzos3	244	19	pathogenesis	pathogenesis	NN
cord-003614-63rzzos3	244	20	of	of	IN
cord-003614-63rzzos3	244	21	CDV	CDV	NNP
cord-003614-63rzzos3	244	22	-	-	HYPH
cord-003614-63rzzos3	244	23	induced	induce	VBN
cord-003614-63rzzos3	244	24	leukoencephalitis	leukoencephalitis	NNP
cord-003614-63rzzos3	244	25	remains	remain	VBZ
cord-003614-63rzzos3	244	26	to	to	TO
cord-003614-63rzzos3	244	27	be	be	VB
cord-003614-63rzzos3	244	28	determined	determine	VBN
cord-003614-63rzzos3	244	29	.	.	.
cord-003614-63rzzos3	245	1	The	the	DT
cord-003614-63rzzos3	245	2	present	present	JJ
cord-003614-63rzzos3	245	3	study	study	NN
cord-003614-63rzzos3	245	4	showed	show	VBD
cord-003614-63rzzos3	245	5	a	a	DT
cord-003614-63rzzos3	245	6	significant	significant	JJ
cord-003614-63rzzos3	245	7	increase	increase	NN
cord-003614-63rzzos3	245	8	in	in	IN
cord-003614-63rzzos3	245	9	the	the	DT
cord-003614-63rzzos3	245	10	expression	expression	NN
cord-003614-63rzzos3	245	11	of	of	IN
cord-003614-63rzzos3	245	12	MX	MX	NNP
cord-003614-63rzzos3	245	13	proteins	protein	NNS
cord-003614-63rzzos3	245	14	during	during	IN
cord-003614-63rzzos3	245	15	all	all	DT
cord-003614-63rzzos3	245	16	stages	stage	NNS
cord-003614-63rzzos3	245	17	of	of	IN
cord-003614-63rzzos3	245	18	canine	canine	JJ
cord-003614-63rzzos3	245	19	distemper	distemper	NN
cord-003614-63rzzos3	245	20	leukoencephalitis	leukoencephalitis	NNP
cord-003614-63rzzos3	245	21	,	,	,
cord-003614-63rzzos3	245	22	which	which	WDT
cord-003614-63rzzos3	245	23	was	be	VBD
cord-003614-63rzzos3	245	24	even	even	RB
cord-003614-63rzzos3	245	25	found	find	VBN
cord-003614-63rzzos3	245	26	in	in	IN
cord-003614-63rzzos3	245	27	CDV	CDV	NNP
cord-003614-63rzzos3	245	28	-	-	HYPH
cord-003614-63rzzos3	245	29	infected	infect	VBN
cord-003614-63rzzos3	245	30	areas	area	NNS
cord-003614-63rzzos3	245	31	without	without	IN
cord-003614-63rzzos3	245	32	histological	histological	JJ
cord-003614-63rzzos3	245	33	lesions	lesion	NNS
cord-003614-63rzzos3	245	34	.	.	.
cord-003614-63rzzos3	246	1	The	the	DT
cord-003614-63rzzos3	246	2	presence	presence	NN
cord-003614-63rzzos3	246	3	of	of	IN
cord-003614-63rzzos3	246	4	MX	MX	NNP
cord-003614-63rzzos3	246	5	proteins	protein	NNS
cord-003614-63rzzos3	246	6	in	in	IN
cord-003614-63rzzos3	246	7	neurons	neuron	NNS
cord-003614-63rzzos3	246	8	and	and	CC
cord-003614-63rzzos3	246	9	endothelial	endothelial	JJ
cord-003614-63rzzos3	246	10	cells	cell	NNS
cord-003614-63rzzos3	246	11	of	of	IN
cord-003614-63rzzos3	246	12	the	the	DT
cord-003614-63rzzos3	246	13	normal	normal	JJ
cord-003614-63rzzos3	246	14	canine	canine	JJ
cord-003614-63rzzos3	246	15	brain	brain	NN
cord-003614-63rzzos3	246	16	demonstrates	demonstrate	VBZ
cord-003614-63rzzos3	246	17	a	a	DT
cord-003614-63rzzos3	246	18	low	low	JJ
cord-003614-63rzzos3	246	19	but	but	CC
cord-003614-63rzzos3	246	20	constitutive	constitutive	JJ
cord-003614-63rzzos3	246	21	expression	expression	NN
cord-003614-63rzzos3	246	22	of	of	IN
cord-003614-63rzzos3	246	23	this	this	DT
cord-003614-63rzzos3	246	24	antiviral	antiviral	JJ
cord-003614-63rzzos3	246	25	protein	protein	NN
cord-003614-63rzzos3	246	26	,	,	,
cord-003614-63rzzos3	246	27	whose	whose	WP$
cord-003614-63rzzos3	246	28	expression	expression	NN
cord-003614-63rzzos3	246	29	was	be	VBD
cord-003614-63rzzos3	246	30	described	describe	VBN
cord-003614-63rzzos3	246	31	to	to	TO
cord-003614-63rzzos3	246	32	be	be	VB
cord-003614-63rzzos3	246	33	strictly	strictly	RB
cord-003614-63rzzos3	246	34	dependent	dependent	JJ
cord-003614-63rzzos3	246	35	on	on	IN
cord-003614-63rzzos3	246	36	IFN	IFN	NNP
cord-003614-63rzzos3	246	37	-	-	HYPH
cord-003614-63rzzos3	246	38	I	I	NNP
cord-003614-63rzzos3	246	39	[	[	-LRB-
cord-003614-63rzzos3	246	40	102	102	CD
cord-003614-63rzzos3	246	41	]	]	-RRB-
cord-003614-63rzzos3	246	42	.	.	.
cord-003614-63rzzos3	247	1	Similarly	similarly	RB
cord-003614-63rzzos3	247	2	,	,	,
cord-003614-63rzzos3	247	3	Porter	Porter	NNP
cord-003614-63rzzos3	247	4	et	et	NNP
cord-003614-63rzzos3	247	5	al	al	NNP
cord-003614-63rzzos3	247	6	.	.	.
cord-003614-63rzzos3	248	1	(	(	-LRB-
cord-003614-63rzzos3	248	2	2006	2006	CD
cord-003614-63rzzos3	248	3	)	)	-RRB-
cord-003614-63rzzos3	248	4	found	find	VBD
cord-003614-63rzzos3	248	5	a	a	DT
cord-003614-63rzzos3	248	6	strong	strong	JJ
cord-003614-63rzzos3	248	7	MX	MX	NNP
cord-003614-63rzzos3	248	8	expression	expression	NN
cord-003614-63rzzos3	248	9	in	in	IN
cord-003614-63rzzos3	248	10	astrocytes	astrocyte	NNS
cord-003614-63rzzos3	248	11	,	,	,
cord-003614-63rzzos3	248	12	macrophages	macrophage	NNS
cord-003614-63rzzos3	248	13	/	/	SYM
cord-003614-63rzzos3	248	14	microglia	microglia	NNS
cord-003614-63rzzos3	248	15	and	and	CC
cord-003614-63rzzos3	248	16	neurons	neuron	NNS
cord-003614-63rzzos3	248	17	in	in	IN
cord-003614-63rzzos3	248	18	CDV	CDV	NNP
cord-003614-63rzzos3	248	19	-	-	HYPH
cord-003614-63rzzos3	248	20	infected	infect	VBN
cord-003614-63rzzos3	248	21	brain	brain	NN
cord-003614-63rzzos3	248	22	tissue	tissue	NN
cord-003614-63rzzos3	248	23	[	[	-LRB-
cord-003614-63rzzos3	248	24	44	44	CD
cord-003614-63rzzos3	248	25	]	]	-RRB-
cord-003614-63rzzos3	248	26	.	.	.
cord-003614-63rzzos3	249	1	Endothelial	endothelial	JJ
cord-003614-63rzzos3	249	2	cells	cell	NNS
cord-003614-63rzzos3	249	3	were	be	VBD
cord-003614-63rzzos3	249	4	also	also	RB
cord-003614-63rzzos3	249	5	described	describe	VBN
cord-003614-63rzzos3	249	6	to	to	TO
cord-003614-63rzzos3	249	7	be	be	VB
cord-003614-63rzzos3	249	8	immunopositive	immunopositive	JJ
cord-003614-63rzzos3	249	9	for	for	IN
cord-003614-63rzzos3	249	10	MX	MX	NNP
cord-003614-63rzzos3	249	11	by	by	IN
cord-003614-63rzzos3	249	12	Porter	Porter	NNP
cord-003614-63rzzos3	249	13	et	et	NNP
cord-003614-63rzzos3	249	14	al	al	NNP
cord-003614-63rzzos3	249	15	.	.	.
cord-003614-63rzzos3	250	1	(	(	-LRB-
cord-003614-63rzzos3	250	2	2006	2006	CD
cord-003614-63rzzos3	250	3	)	)	-RRB-
cord-003614-63rzzos3	250	4	,	,	,
cord-003614-63rzzos3	250	5	but	but	CC
cord-003614-63rzzos3	250	6	this	this	DT
cord-003614-63rzzos3	250	7	staining	staining	NN
cord-003614-63rzzos3	250	8	was	be	VBD
cord-003614-63rzzos3	250	9	interpreted	interpret	VBN
cord-003614-63rzzos3	250	10	as	as	IN
cord-003614-63rzzos3	250	11	non	non	JJ
cord-003614-63rzzos3	250	12	-	-	JJ
cord-003614-63rzzos3	250	13	specific	specific	JJ
cord-003614-63rzzos3	250	14	[	[	-LRB-
cord-003614-63rzzos3	250	15	44	44	CD
cord-003614-63rzzos3	250	16	]	]	-RRB-
cord-003614-63rzzos3	250	17	.	.	.
cord-003614-63rzzos3	251	1	However	however	RB
cord-003614-63rzzos3	251	2	,	,	,
cord-003614-63rzzos3	251	3	strong	strong	JJ
cord-003614-63rzzos3	251	4	expression	expression	NN
cord-003614-63rzzos3	251	5	of	of	IN
cord-003614-63rzzos3	251	6	MX	MX	NNP
cord-003614-63rzzos3	251	7	proteins	protein	NNS
cord-003614-63rzzos3	251	8	in	in	IN
cord-003614-63rzzos3	251	9	canine	canine	JJ
cord-003614-63rzzos3	251	10	distemper	distemper	NN
cord-003614-63rzzos3	251	11	lesions	lesion	NNS
cord-003614-63rzzos3	251	12	most	most	RBS
cord-003614-63rzzos3	251	13	likely	likely	RB
cord-003614-63rzzos3	251	14	impedes	impede	VBZ
cord-003614-63rzzos3	251	15	viral	viral	JJ
cord-003614-63rzzos3	251	16	replication	replication	NN
cord-003614-63rzzos3	251	17	and	and	CC
cord-003614-63rzzos3	251	18	,	,	,
cord-003614-63rzzos3	251	19	similar	similar	JJ
cord-003614-63rzzos3	251	20	to	to	IN
cord-003614-63rzzos3	251	21	increased	increase	VBN
cord-003614-63rzzos3	251	22	ISG15	isg15	NN
cord-003614-63rzzos3	251	23	,	,	,
cord-003614-63rzzos3	251	24	PKR	PKR	NNP
cord-003614-63rzzos3	251	25	and	and	CC
cord-003614-63rzzos3	251	26	OAS	OAS	NNP
cord-003614-63rzzos3	251	27	levels	level	NNS
cord-003614-63rzzos3	251	28	,	,	,
cord-003614-63rzzos3	251	29	contributes	contribute	VBZ
cord-003614-63rzzos3	251	30	to	to	IN
cord-003614-63rzzos3	251	31	the	the	DT
cord-003614-63rzzos3	251	32	typical	typical	JJ
cord-003614-63rzzos3	251	33	decrease	decrease	NN
cord-003614-63rzzos3	251	34	in	in	IN
cord-003614-63rzzos3	251	35	viral	viral	JJ
cord-003614-63rzzos3	251	36	antigen	antigen	NN
cord-003614-63rzzos3	251	37	observed	observe	VBN
cord-003614-63rzzos3	251	38	during	during	IN
cord-003614-63rzzos3	251	39	the	the	DT
cord-003614-63rzzos3	251	40	progression	progression	NN
cord-003614-63rzzos3	251	41	of	of	IN
cord-003614-63rzzos3	251	42	the	the	DT
cord-003614-63rzzos3	251	43	disease	disease	NN
cord-003614-63rzzos3	251	44	[	[	-LRB-
cord-003614-63rzzos3	251	45	2	2	CD
cord-003614-63rzzos3	251	46	,	,	,
cord-003614-63rzzos3	251	47	4	4	CD
cord-003614-63rzzos3	251	48	,	,	,
cord-003614-63rzzos3	251	49	103	103	CD
cord-003614-63rzzos3	251	50	]	]	-RRB-
cord-003614-63rzzos3	251	51	.	.	.
cord-003614-63rzzos3	252	1	Moreover	moreover	RB
cord-003614-63rzzos3	252	2	,	,	,
cord-003614-63rzzos3	252	3	the	the	DT
cord-003614-63rzzos3	252	4	low	low	JJ
cord-003614-63rzzos3	252	5	number	number	NN
cord-003614-63rzzos3	252	6	of	of	IN
cord-003614-63rzzos3	252	7	CDV	CDV	NNP
cord-003614-63rzzos3	252	8	-	-	HYPH
cord-003614-63rzzos3	252	9	infected	infect	VBN
cord-003614-63rzzos3	252	10	cells	cell	NNS
cord-003614-63rzzos3	252	11	expressing	express	VBG
cord-003614-63rzzos3	252	12	STAT1	stat1	NN
cord-003614-63rzzos3	252	13	,	,	,
cord-003614-63rzzos3	252	14	STAT2	STAT2	NNS
cord-003614-63rzzos3	252	15	and	and	CC
cord-003614-63rzzos3	252	16	MX	MX	NNP
cord-003614-63rzzos3	252	17	indicates	indicate	VBZ
cord-003614-63rzzos3	252	18	that	that	IN
cord-003614-63rzzos3	252	19	the	the	DT
cord-003614-63rzzos3	252	20	expression	expression	NN
cord-003614-63rzzos3	252	21	of	of	IN
cord-003614-63rzzos3	252	22	these	these	DT
cord-003614-63rzzos3	252	23	type	type	NN
cord-003614-63rzzos3	252	24	I	-PRON-	PRP
cord-003614-63rzzos3	252	25	IFN	IFN	NNP
cord-003614-63rzzos3	252	26	pathway	pathway	NN
cord-003614-63rzzos3	252	27	members	member	NNS
cord-003614-63rzzos3	252	28	is	be	VBZ
cord-003614-63rzzos3	252	29	not	not	RB
cord-003614-63rzzos3	252	30	directly	directly	RB
cord-003614-63rzzos3	252	31	induced	induce	VBN
cord-003614-63rzzos3	252	32	by	by	IN
cord-003614-63rzzos3	252	33	virus	virus	NN
cord-003614-63rzzos3	252	34	infection	infection	NN
cord-003614-63rzzos3	252	35	.	.	.
cord-003614-63rzzos3	253	1	The	the	DT
cord-003614-63rzzos3	253	2	strong	strong	JJ
cord-003614-63rzzos3	253	3	expression	expression	NN
cord-003614-63rzzos3	253	4	of	of	IN
cord-003614-63rzzos3	253	5	STAT1	stat1	NN
cord-003614-63rzzos3	253	6	,	,	,
cord-003614-63rzzos3	253	7	STAT2	STAT2	NNS
cord-003614-63rzzos3	253	8	and	and	CC
cord-003614-63rzzos3	253	9	downstream	downstream	JJ
cord-003614-63rzzos3	253	10	ISG	ISG	NNP
cord-003614-63rzzos3	253	11	proteins	protein	NNS
cord-003614-63rzzos3	253	12	in	in	IN
cord-003614-63rzzos3	253	13	oligodendrocytes	oligodendrocyte	NNS
cord-003614-63rzzos3	253	14	and	and	CC
cord-003614-63rzzos3	253	15	neurons	neuron	NNS
cord-003614-63rzzos3	253	16	is	be	VBZ
cord-003614-63rzzos3	253	17	probably	probably	RB
cord-003614-63rzzos3	253	18	related	related	JJ
cord-003614-63rzzos3	253	19	to	to	IN
cord-003614-63rzzos3	253	20	their	-PRON-	PRP$
cord-003614-63rzzos3	253	21	well	well	RB
cord-003614-63rzzos3	253	22	-	-	HYPH
cord-003614-63rzzos3	253	23	known	know	VBN
cord-003614-63rzzos3	253	24	restricted	restrict	VBN
cord-003614-63rzzos3	253	25	CDV	CDV	NNP
cord-003614-63rzzos3	253	26	infection	infection	NN
cord-003614-63rzzos3	253	27	,	,	,
cord-003614-63rzzos3	253	28	which	which	WDT
cord-003614-63rzzos3	253	29	is	be	VBZ
cord-003614-63rzzos3	253	30	characterized	characterize	VBN
cord-003614-63rzzos3	253	31	by	by	IN
cord-003614-63rzzos3	253	32	the	the	DT
cord-003614-63rzzos3	253	33	presence	presence	NN
cord-003614-63rzzos3	253	34	of	of	IN
cord-003614-63rzzos3	253	35	CDV	CDV	NNP
cord-003614-63rzzos3	253	36	nucleic	nucleic	JJ
cord-003614-63rzzos3	253	37	acid	acid	NN
cord-003614-63rzzos3	253	38	sequences	sequence	NNS
cord-003614-63rzzos3	253	39	and	and	CC
cord-003614-63rzzos3	253	40	lack	lack	NN
cord-003614-63rzzos3	253	41	of	of	IN
cord-003614-63rzzos3	253	42	viral	viral	JJ
cord-003614-63rzzos3	253	43	antigen	antigen	NN
cord-003614-63rzzos3	253	44	[	[	-LRB-
cord-003614-63rzzos3	253	45	4	4	CD
cord-003614-63rzzos3	253	46	]	]	-RRB-
cord-003614-63rzzos3	253	47	.	.	.
cord-003614-63rzzos3	254	1	In	in	IN
cord-003614-63rzzos3	254	2	contrast	contrast	NN
cord-003614-63rzzos3	254	3	,	,	,
cord-003614-63rzzos3	254	4	astrocytes	astrocyte	NNS
cord-003614-63rzzos3	254	5	did	do	VBD
cord-003614-63rzzos3	254	6	not	not	RB
cord-003614-63rzzos3	254	7	express	express	VB
cord-003614-63rzzos3	254	8	STAT2	STAT2	NNS
cord-003614-63rzzos3	254	9	proteins	protein	NNS
cord-003614-63rzzos3	254	10	,	,	,
cord-003614-63rzzos3	254	11	which	which	WDT
cord-003614-63rzzos3	254	12	favors	favor	VBZ
cord-003614-63rzzos3	254	13	viral	viral	JJ
cord-003614-63rzzos3	254	14	replication	replication	NN
cord-003614-63rzzos3	254	15	in	in	IN
cord-003614-63rzzos3	254	16	these	these	DT
cord-003614-63rzzos3	254	17	cells	cell	NNS
cord-003614-63rzzos3	254	18	due	due	JJ
cord-003614-63rzzos3	254	19	to	to	IN
cord-003614-63rzzos3	254	20	the	the	DT
cord-003614-63rzzos3	254	21	blocking	blocking	NN
cord-003614-63rzzos3	254	22	of	of	IN
cord-003614-63rzzos3	254	23	the	the	DT
cord-003614-63rzzos3	254	24	canonical	canonical	JJ
cord-003614-63rzzos3	254	25	JAK	JAK	NNP
cord-003614-63rzzos3	254	26	-	-	HYPH
cord-003614-63rzzos3	254	27	STAT	stat	NN
cord-003614-63rzzos3	254	28	pathway	pathway	NN
cord-003614-63rzzos3	254	29	.	.	.
cord-003614-63rzzos3	255	1	The	the	DT
cord-003614-63rzzos3	255	2	cell	cell	NN
cord-003614-63rzzos3	255	3	-	-	HYPH
cord-003614-63rzzos3	255	4	type	type	NN
cord-003614-63rzzos3	255	5	specific	specific	JJ
cord-003614-63rzzos3	255	6	differences	difference	NNS
cord-003614-63rzzos3	255	7	in	in	IN
cord-003614-63rzzos3	255	8	the	the	DT
cord-003614-63rzzos3	255	9	activation	activation	NN
cord-003614-63rzzos3	255	10	of	of	IN
cord-003614-63rzzos3	255	11	the	the	DT
cord-003614-63rzzos3	255	12	IFN	IFN	NNP
cord-003614-63rzzos3	255	13	-	-	HYPH
cord-003614-63rzzos3	255	14	I	I	NNP
cord-003614-63rzzos3	255	15	pathway	pathway	NN
cord-003614-63rzzos3	255	16	might	may	MD
cord-003614-63rzzos3	255	17	also	also	RB
cord-003614-63rzzos3	255	18	explain	explain	VB
cord-003614-63rzzos3	255	19	the	the	DT
cord-003614-63rzzos3	255	20	fact	fact	NN
cord-003614-63rzzos3	255	21	that	that	IN
cord-003614-63rzzos3	255	22	up	up	IN
cord-003614-63rzzos3	255	23	to	to	TO
cord-003614-63rzzos3	255	24	95	95	CD
cord-003614-63rzzos3	255	25	%	%	NN
cord-003614-63rzzos3	255	26	of	of	IN
cord-003614-63rzzos3	255	27	all	all	DT
cord-003614-63rzzos3	255	28	CDV	CDV	NNP
cord-003614-63rzzos3	255	29	-	-	HYPH
cord-003614-63rzzos3	255	30	infected	infect	VBN
cord-003614-63rzzos3	255	31	cells	cell	NNS
cord-003614-63rzzos3	255	32	within	within	IN
cord-003614-63rzzos3	255	33	acute	acute	JJ
cord-003614-63rzzos3	255	34	lesions	lesion	NNS
cord-003614-63rzzos3	255	35	are	be	VBP
cord-003614-63rzzos3	255	36	astrocytes	astrocyte	NNS
cord-003614-63rzzos3	255	37	[	[	-LRB-
cord-003614-63rzzos3	255	38	104	104	CD
cord-003614-63rzzos3	255	39	]	]	-RRB-
cord-003614-63rzzos3	255	40	,	,	,
cord-003614-63rzzos3	255	41	whereas	whereas	IN
cord-003614-63rzzos3	255	42	oligodendrocytes	oligodendrocyte	NNS
cord-003614-63rzzos3	255	43	hardly	hardly	RB
cord-003614-63rzzos3	255	44	express	express	VBP
cord-003614-63rzzos3	255	45	CDV	CDV	NNP
cord-003614-63rzzos3	255	46	protein	protein	NN
cord-003614-63rzzos3	255	47	[	[	-LRB-
cord-003614-63rzzos3	255	48	105	105	CD
cord-003614-63rzzos3	255	49	]	]	-RRB-
cord-003614-63rzzos3	255	50	.	.	.
cord-003614-63rzzos3	256	1	However	however	RB
cord-003614-63rzzos3	256	2	,	,	,
cord-003614-63rzzos3	256	3	the	the	DT
cord-003614-63rzzos3	256	4	restriction	restriction	NN
cord-003614-63rzzos3	256	5	of	of	IN
cord-003614-63rzzos3	256	6	virus	virus	NN
cord-003614-63rzzos3	256	7	replication	replication	NN
cord-003614-63rzzos3	256	8	in	in	IN
cord-003614-63rzzos3	256	9	neurons	neuron	NNS
cord-003614-63rzzos3	256	10	and	and	CC
cord-003614-63rzzos3	256	11	oligodendrocytes	oligodendrocyte	NNS
cord-003614-63rzzos3	256	12	does	do	VBZ
cord-003614-63rzzos3	256	13	not	not	RB
cord-003614-63rzzos3	256	14	prevent	prevent	VB
cord-003614-63rzzos3	256	15	axonal	axonal	JJ
cord-003614-63rzzos3	256	16	pathology	pathology	NN
cord-003614-63rzzos3	256	17	and	and	CC
cord-003614-63rzzos3	256	18	massive	massive	JJ
cord-003614-63rzzos3	256	19	down	down	JJ
cord-003614-63rzzos3	256	20	-	-	HYPH
cord-003614-63rzzos3	256	21	regulation	regulation	NN
cord-003614-63rzzos3	256	22	of	of	IN
cord-003614-63rzzos3	256	23	myelin	myelin	JJ
cord-003614-63rzzos3	256	24	gene	gene	NN
cord-003614-63rzzos3	256	25	expression	expression	NN
cord-003614-63rzzos3	256	26	(	(	-LRB-
cord-003614-63rzzos3	256	27	oligodendrocyte	oligodendrocyte	NNP
cord-003614-63rzzos3	256	28	dystrophy	dystrophy	NNP
cord-003614-63rzzos3	256	29	)	)	-RRB-
cord-003614-63rzzos3	256	30	[	[	-LRB-
cord-003614-63rzzos3	256	31	105	105	CD
cord-003614-63rzzos3	256	32	,	,	,
cord-003614-63rzzos3	256	33	106	106	CD
cord-003614-63rzzos3	256	34	]	]	-RRB-
cord-003614-63rzzos3	256	35	.	.	.
cord-003614-63rzzos3	257	1	Both	both	DT
cord-003614-63rzzos3	257	2	processes	process	NNS
cord-003614-63rzzos3	257	3	contribute	contribute	VBP
cord-003614-63rzzos3	257	4	to	to	IN
cord-003614-63rzzos3	257	5	the	the	DT
cord-003614-63rzzos3	257	6	initiation	initiation	NN
cord-003614-63rzzos3	257	7	of	of	IN
cord-003614-63rzzos3	257	8	the	the	DT
cord-003614-63rzzos3	257	9	demyelination	demyelination	NN
cord-003614-63rzzos3	257	10	process	process	NN
cord-003614-63rzzos3	257	11	,	,	,
cord-003614-63rzzos3	257	12	whereas	whereas	IN
cord-003614-63rzzos3	257	13	later	later	JJ
cord-003614-63rzzos3	257	14	stages	stage	NNS
cord-003614-63rzzos3	257	15	of	of	IN
cord-003614-63rzzos3	257	16	demyelination	demyelination	NN
cord-003614-63rzzos3	257	17	are	be	VBP
cord-003614-63rzzos3	257	18	mainly	mainly	RB
cord-003614-63rzzos3	257	19	mediated	mediate	VBN
cord-003614-63rzzos3	257	20	by	by	IN
cord-003614-63rzzos3	257	21	so	so	RB
cord-003614-63rzzos3	257	22	-	-	HYPH
cord-003614-63rzzos3	257	23	called	call	VBN
cord-003614-63rzzos3	257	24	bystander	bystander	NN
cord-003614-63rzzos3	257	25	mechanisms	mechanism	NNS
cord-003614-63rzzos3	257	26	[	[	-LRB-
cord-003614-63rzzos3	257	27	2	2	CD
cord-003614-63rzzos3	257	28	,	,	,
cord-003614-63rzzos3	257	29	4	4	CD
cord-003614-63rzzos3	257	30	,	,	,
cord-003614-63rzzos3	257	31	47	47	CD
cord-003614-63rzzos3	257	32	,	,	,
cord-003614-63rzzos3	257	33	107	107	CD
cord-003614-63rzzos3	257	34	]	]	-RRB-
cord-003614-63rzzos3	257	35	.	.	.
cord-003614-63rzzos3	258	1	This	this	DT
cord-003614-63rzzos3	258	2	bystander	bystander	NN
cord-003614-63rzzos3	258	3	demyelination	demyelination	NN
cord-003614-63rzzos3	258	4	results	result	VBZ
cord-003614-63rzzos3	258	5	from	from	IN
cord-003614-63rzzos3	258	6	the	the	DT
cord-003614-63rzzos3	258	7	activation	activation	NN
cord-003614-63rzzos3	258	8	of	of	IN
cord-003614-63rzzos3	258	9	macrophages	macrophage	NNS
cord-003614-63rzzos3	258	10	/	/	SYM
cord-003614-63rzzos3	258	11	microglia	microglia	NNS
cord-003614-63rzzos3	258	12	,	,	,
cord-003614-63rzzos3	258	13	which	which	WDT
cord-003614-63rzzos3	258	14	is	be	VBZ
cord-003614-63rzzos3	258	15	characterized	characterize	VBN
cord-003614-63rzzos3	258	16	by	by	IN
cord-003614-63rzzos3	258	17	an	an	DT
cord-003614-63rzzos3	258	18	increased	increase	VBN
cord-003614-63rzzos3	258	19	phagocytic	phagocytic	JJ
cord-003614-63rzzos3	258	20	activity	activity	NN
cord-003614-63rzzos3	258	21	,	,	,
cord-003614-63rzzos3	258	22	oxygen	oxygen	NN
cord-003614-63rzzos3	258	23	radical	radical	JJ
cord-003614-63rzzos3	258	24	production	production	NN
cord-003614-63rzzos3	258	25	and	and	CC
cord-003614-63rzzos3	258	26	expression	expression	NN
cord-003614-63rzzos3	258	27	of	of	IN
cord-003614-63rzzos3	258	28	MHC	MHC	NNP
cord-003614-63rzzos3	258	29	class	class	NN
cord-003614-63rzzos3	258	30	II	II	NNP
cord-003614-63rzzos3	258	31	molecules	molecule	NNS
cord-003614-63rzzos3	258	32	and	and	CC
cord-003614-63rzzos3	258	33	the	the	DT
cord-003614-63rzzos3	258	34	release	release	NN
cord-003614-63rzzos3	258	35	of	of	IN
cord-003614-63rzzos3	258	36	myelin	myelin	JJ
cord-003614-63rzzos3	258	37	damaging	damaging	JJ
cord-003614-63rzzos3	258	38	enzymes	enzyme	NNS
cord-003614-63rzzos3	258	39	such	such	JJ
cord-003614-63rzzos3	258	40	as	as	IN
cord-003614-63rzzos3	258	41	matrix	matrix	NN
cord-003614-63rzzos3	258	42	-	-	HYPH
cord-003614-63rzzos3	258	43	metalloproteinases	metalloproteinase	NNS
cord-003614-63rzzos3	258	44	(	(	-LRB-
cord-003614-63rzzos3	258	45	MMPs	MMPs	NNP
cord-003614-63rzzos3	258	46	)	)	-RRB-
cord-003614-63rzzos3	258	47	[	[	-LRB-
cord-003614-63rzzos3	258	48	2	2	CD
cord-003614-63rzzos3	258	49	,	,	,
cord-003614-63rzzos3	258	50	4	4	CD
cord-003614-63rzzos3	258	51	,	,	,
cord-003614-63rzzos3	258	52	[	[	-LRB-
cord-003614-63rzzos3	258	53	108	108	CD
cord-003614-63rzzos3	258	54	]	]	-RRB-
cord-003614-63rzzos3	258	55	[	[	-LRB-
cord-003614-63rzzos3	258	56	109	109	CD
cord-003614-63rzzos3	258	57	]	]	-RRB-
cord-003614-63rzzos3	258	58	[	[	-LRB-
cord-003614-63rzzos3	258	59	110	110	CD
cord-003614-63rzzos3	258	60	]	]	-RRB-
cord-003614-63rzzos3	258	61	.	.	.
cord-003614-63rzzos3	259	1	The	the	DT
cord-003614-63rzzos3	259	2	progressive	progressive	JJ
cord-003614-63rzzos3	259	3	development	development	NN
cord-003614-63rzzos3	259	4	of	of	IN
cord-003614-63rzzos3	259	5	demyelination	demyelination	NN
cord-003614-63rzzos3	259	6	is	be	VBZ
cord-003614-63rzzos3	259	7	driven	drive	VBN
cord-003614-63rzzos3	259	8	by	by	IN
cord-003614-63rzzos3	259	9	a	a	DT
cord-003614-63rzzos3	259	10	strong	strong	JJ
cord-003614-63rzzos3	259	11	continuous	continuous	JJ
cord-003614-63rzzos3	259	12	expression	expression	NN
cord-003614-63rzzos3	259	13	of	of	IN
cord-003614-63rzzos3	259	14	IL1	IL1	NNP
cord-003614-63rzzos3	259	15	,	,	,
cord-003614-63rzzos3	259	16	IL6	IL6	NNP
cord-003614-63rzzos3	259	17	,	,	,
cord-003614-63rzzos3	259	18	IL8	IL8	NNP
cord-003614-63rzzos3	259	19	,	,	,
cord-003614-63rzzos3	259	20	IL12	IL12	NNP
cord-003614-63rzzos3	259	21	and	and	CC
cord-003614-63rzzos3	259	22	TNFα	TNFα	NNS
cord-003614-63rzzos3	259	23	promoting	promote	VBG
cord-003614-63rzzos3	259	24	innate	innate	JJ
cord-003614-63rzzos3	259	25	and	and	CC
cord-003614-63rzzos3	259	26	Th1-biased	th1-biased	JJ
cord-003614-63rzzos3	259	27	immune	immune	JJ
cord-003614-63rzzos3	259	28	responses	response	NNS
cord-003614-63rzzos3	259	29	[	[	-LRB-
cord-003614-63rzzos3	259	30	2	2	CD
cord-003614-63rzzos3	259	31	,	,	,
cord-003614-63rzzos3	259	32	4	4	CD
cord-003614-63rzzos3	259	33	,	,	,
cord-003614-63rzzos3	259	34	80	80	CD
cord-003614-63rzzos3	259	35	,	,	,
cord-003614-63rzzos3	259	36	[	[	-LRB-
cord-003614-63rzzos3	259	37	111	111	CD
cord-003614-63rzzos3	259	38	]	]	-RRB-
cord-003614-63rzzos3	259	39	[	[	-LRB-
cord-003614-63rzzos3	259	40	112	112	CD
cord-003614-63rzzos3	259	41	]	]	-RRB-
cord-003614-63rzzos3	259	42	[	[	-LRB-
cord-003614-63rzzos3	259	43	113	113	CD
cord-003614-63rzzos3	259	44	]	]	-RRB-
cord-003614-63rzzos3	259	45	.	.	.
cord-003614-63rzzos3	260	1	Interestingly	interestingly	RB
cord-003614-63rzzos3	260	2	,	,	,
cord-003614-63rzzos3	260	3	recent	recent	JJ
cord-003614-63rzzos3	260	4	studies	study	NNS
cord-003614-63rzzos3	260	5	demonstrated	demonstrate	VBD
cord-003614-63rzzos3	260	6	that	that	IN
cord-003614-63rzzos3	260	7	the	the	DT
cord-003614-63rzzos3	260	8	IFN	IFN	NNP
cord-003614-63rzzos3	260	9	-	-	HYPH
cord-003614-63rzzos3	260	10	I	I	NNP
cord-003614-63rzzos3	260	11	pathway	pathway	NN
cord-003614-63rzzos3	260	12	is	be	VBZ
cord-003614-63rzzos3	260	13	critically	critically	RB
cord-003614-63rzzos3	260	14	involved	involve	VBN
cord-003614-63rzzos3	260	15	in	in	IN
cord-003614-63rzzos3	260	16	the	the	DT
cord-003614-63rzzos3	260	17	differentiation	differentiation	NN
cord-003614-63rzzos3	260	18	and	and	CC
cord-003614-63rzzos3	260	19	activation	activation	NN
cord-003614-63rzzos3	260	20	of	of	IN
cord-003614-63rzzos3	260	21	immune	immune	JJ
cord-003614-63rzzos3	260	22	cells	cell	NNS
cord-003614-63rzzos3	260	23	as	as	RB
cord-003614-63rzzos3	260	24	well	well	RB
cord-003614-63rzzos3	260	25	as	as	IN
cord-003614-63rzzos3	260	26	the	the	DT
cord-003614-63rzzos3	260	27	expression	expression	NN
cord-003614-63rzzos3	260	28	of	of	IN
cord-003614-63rzzos3	260	29	MMPs	mmp	NNS
cord-003614-63rzzos3	260	30	and	and	CC
cord-003614-63rzzos3	260	31	pro	pro	JJ
cord-003614-63rzzos3	260	32	-	-	JJ
cord-003614-63rzzos3	260	33	inflammatory	inflammatory	JJ
cord-003614-63rzzos3	260	34	cytokines	cytokine	NNS
cord-003614-63rzzos3	260	35	[	[	-LRB-
cord-003614-63rzzos3	260	36	55	55	CD
cord-003614-63rzzos3	260	37	,	,	,
cord-003614-63rzzos3	260	38	[	[	-LRB-
cord-003614-63rzzos3	260	39	114	114	CD
cord-003614-63rzzos3	260	40	]	]	-RRB-
cord-003614-63rzzos3	260	41	[	[	-LRB-
cord-003614-63rzzos3	260	42	115	115	CD
cord-003614-63rzzos3	260	43	]	]	-RRB-
cord-003614-63rzzos3	260	44	[	[	-LRB-
cord-003614-63rzzos3	260	45	116	116	CD
cord-003614-63rzzos3	260	46	]	]	-RRB-
cord-003614-63rzzos3	260	47	[	[	-LRB-
cord-003614-63rzzos3	260	48	117	117	CD
cord-003614-63rzzos3	260	49	]	]	-RRB-
cord-003614-63rzzos3	260	50	[	[	-LRB-
cord-003614-63rzzos3	260	51	118	118	CD
cord-003614-63rzzos3	260	52	]	]	-RRB-
cord-003614-63rzzos3	260	53	[	[	-LRB-
cord-003614-63rzzos3	260	54	119	119	CD
cord-003614-63rzzos3	260	55	]	]	-RRB-
cord-003614-63rzzos3	260	56	[	[	-LRB-
cord-003614-63rzzos3	260	57	120	120	CD
cord-003614-63rzzos3	260	58	]	]	-RRB-
cord-003614-63rzzos3	260	59	.	.	.
cord-003614-63rzzos3	261	1	IFN	IFN	NNP
cord-003614-63rzzos3	261	2	-	-	HYPH
cord-003614-63rzzos3	261	3	I	-PRON-	PRP
cord-003614-63rzzos3	261	4	can	can	MD
cord-003614-63rzzos3	261	5	modulate	modulate	VB
cord-003614-63rzzos3	261	6	the	the	DT
cord-003614-63rzzos3	261	7	phenotype	phenotype	NN
cord-003614-63rzzos3	261	8	of	of	IN
cord-003614-63rzzos3	261	9	microglia	microglia	NNS
cord-003614-63rzzos3	261	10	,	,	,
cord-003614-63rzzos3	261	11	regulate	regulate	VBP
cord-003614-63rzzos3	261	12	phagocytosis	phagocytosis	NN
cord-003614-63rzzos3	261	13	and	and	CC
cord-003614-63rzzos3	261	14	affect	affect	VB
cord-003614-63rzzos3	261	15	blood	blood	NN
cord-003614-63rzzos3	261	16	-	-	HYPH
cord-003614-63rzzos3	261	17	brain	brain	NN
cord-003614-63rzzos3	261	18	barrier	barrier	NN
cord-003614-63rzzos3	261	19	integrity	integrity	NN
cord-003614-63rzzos3	261	20	[	[	-LRB-
cord-003614-63rzzos3	261	21	115	115	CD
cord-003614-63rzzos3	261	22	]	]	-RRB-
cord-003614-63rzzos3	261	23	.	.	.
cord-003614-63rzzos3	262	1	IRF1	IRF1	NNP
cord-003614-63rzzos3	262	2	is	be	VBZ
cord-003614-63rzzos3	262	3	required	require	VBN
cord-003614-63rzzos3	262	4	for	for	IN
cord-003614-63rzzos3	262	5	NK	NK	NNP
cord-003614-63rzzos3	262	6	cell	cell	NN
cord-003614-63rzzos3	262	7	development	development	NN
cord-003614-63rzzos3	262	8	and	and	CC
cord-003614-63rzzos3	262	9	differentiation	differentiation	NN
cord-003614-63rzzos3	262	10	of	of	IN
cord-003614-63rzzos3	262	11	CD8	CD8	NNP
cord-003614-63rzzos3	262	12	+	+	CC
cord-003614-63rzzos3	262	13	T	T	NNP
cord-003614-63rzzos3	262	14	cells	cell	NNS
cord-003614-63rzzos3	262	15	promotes	promote	VBZ
cord-003614-63rzzos3	262	16	the	the	DT
cord-003614-63rzzos3	262	17	differentiation	differentiation	NN
cord-003614-63rzzos3	262	18	of	of	IN
cord-003614-63rzzos3	262	19	Th1	th1	NN
cord-003614-63rzzos3	262	20	cells	cell	NNS
cord-003614-63rzzos3	262	21	via	via	IN
cord-003614-63rzzos3	262	22	transcriptional	transcriptional	JJ
cord-003614-63rzzos3	262	23	control	control	NN
cord-003614-63rzzos3	262	24	of	of	IN
cord-003614-63rzzos3	262	25	IL12p40	IL12p40	NNP
cord-003614-63rzzos3	262	26	,	,	,
cord-003614-63rzzos3	262	27	inhibits	inhibit	VBZ
cord-003614-63rzzos3	262	28	TNFα	TNFα	NNP
cord-003614-63rzzos3	262	29	-	-	HYPH
cord-003614-63rzzos3	262	30	induced	induce	VBN
cord-003614-63rzzos3	262	31	MMP9	MMP9	NNP
cord-003614-63rzzos3	262	32	expression	expression	NN
cord-003614-63rzzos3	262	33	and	and	CC
cord-003614-63rzzos3	262	34	contributes	contribute	VBZ
cord-003614-63rzzos3	262	35	to	to	IN
cord-003614-63rzzos3	262	36	the	the	DT
cord-003614-63rzzos3	262	37	activation	activation	NN
cord-003614-63rzzos3	262	38	of	of	IN
cord-003614-63rzzos3	262	39	the	the	DT
cord-003614-63rzzos3	262	40	NLRP3	NLRP3	NNP
cord-003614-63rzzos3	262	41	inflammasome	inflammasome	NNP
cord-003614-63rzzos3	262	42	[	[	-LRB-
cord-003614-63rzzos3	262	43	55	55	CD
cord-003614-63rzzos3	262	44	,	,	,
cord-003614-63rzzos3	262	45	114	114	CD
cord-003614-63rzzos3	262	46	,	,	,
cord-003614-63rzzos3	262	47	116	116	CD
cord-003614-63rzzos3	262	48	,	,	,
cord-003614-63rzzos3	262	49	117	117	CD
cord-003614-63rzzos3	262	50	]	]	-RRB-
cord-003614-63rzzos3	262	51	.	.	.
cord-003614-63rzzos3	263	1	IRF3	IRF3	NNP
cord-003614-63rzzos3	263	2	stimulates	stimulate	VBZ
cord-003614-63rzzos3	263	3	the	the	DT
cord-003614-63rzzos3	263	4	transcription	transcription	NN
cord-003614-63rzzos3	263	5	of	of	IN
cord-003614-63rzzos3	263	6	IL6	il6	NN
cord-003614-63rzzos3	263	7	,	,	,
cord-003614-63rzzos3	263	8	IL8	IL8	NNP
cord-003614-63rzzos3	263	9	and	and	CC
cord-003614-63rzzos3	263	10	MMPs	mmp	NNS
cord-003614-63rzzos3	263	11	through	through	IN
cord-003614-63rzzos3	263	12	interaction	interaction	NN
cord-003614-63rzzos3	263	13	with	with	IN
cord-003614-63rzzos3	263	14	c	c	NNP
cord-003614-63rzzos3	263	15	-	-	:
cord-003614-63rzzos3	263	16	Jun	Jun	NNP
cord-003614-63rzzos3	263	17	and	and	CC
cord-003614-63rzzos3	263	18	the	the	DT
cord-003614-63rzzos3	263	19	AP-1	AP-1	NNP
cord-003614-63rzzos3	263	20	promoter	promoter	NN
cord-003614-63rzzos3	263	21	site	site	NN
cord-003614-63rzzos3	263	22	[	[	-LRB-
cord-003614-63rzzos3	263	23	118	118	CD
cord-003614-63rzzos3	263	24	]	]	-RRB-
cord-003614-63rzzos3	263	25	[	[	-LRB-
cord-003614-63rzzos3	263	26	119	119	CD
cord-003614-63rzzos3	263	27	]	]	-RRB-
cord-003614-63rzzos3	263	28	[	[	-LRB-
cord-003614-63rzzos3	263	29	120	120	CD
cord-003614-63rzzos3	263	30	]	]	-RRB-
cord-003614-63rzzos3	263	31	.	.	.
cord-003614-63rzzos3	264	1	IRF7	IRF7	NNP
cord-003614-63rzzos3	264	2	regulates	regulate	VBZ
cord-003614-63rzzos3	264	3	the	the	DT
cord-003614-63rzzos3	264	4	expression	expression	NN
cord-003614-63rzzos3	264	5	of	of	IN
cord-003614-63rzzos3	264	6	IL6	il6	NN
cord-003614-63rzzos3	264	7	through	through	IN
cord-003614-63rzzos3	264	8	stabilization	stabilization	NN
cord-003614-63rzzos3	264	9	of	of	IN
cord-003614-63rzzos3	264	10	IL6	IL6	NNP
cord-003614-63rzzos3	264	11	mRNA	mRNA	NNP
cord-003614-63rzzos3	264	12	and	and	CC
cord-003614-63rzzos3	264	13	induces	induce	VBZ
cord-003614-63rzzos3	264	14	the	the	DT
cord-003614-63rzzos3	264	15	transcription	transcription	NN
cord-003614-63rzzos3	264	16	of	of	IN
cord-003614-63rzzos3	264	17	CXCL10	CXCL10	NNP
cord-003614-63rzzos3	264	18	,	,	,
cord-003614-63rzzos3	264	19	a	a	DT
cord-003614-63rzzos3	264	20	chemokine	chemokine	NN
cord-003614-63rzzos3	264	21	for	for	IN
cord-003614-63rzzos3	264	22	macrophages	macrophage	NNS
cord-003614-63rzzos3	264	23	,	,	,
cord-003614-63rzzos3	264	24	T	t	NN
cord-003614-63rzzos3	264	25	cells	cell	NNS
cord-003614-63rzzos3	264	26	and	and	CC
cord-003614-63rzzos3	264	27	NK	NK	NNP
cord-003614-63rzzos3	264	28	cells	cell	NNS
cord-003614-63rzzos3	264	29	[	[	-LRB-
cord-003614-63rzzos3	264	30	118	118	CD
cord-003614-63rzzos3	264	31	]	]	-RRB-
cord-003614-63rzzos3	264	32	.	.	.
cord-003614-63rzzos3	265	1	Moreover	moreover	RB
cord-003614-63rzzos3	265	2	,	,	,
cord-003614-63rzzos3	265	3	studies	study	NNS
cord-003614-63rzzos3	265	4	of	of	IN
cord-003614-63rzzos3	265	5	monogenic	monogenic	NNP
cord-003614-63rzzos3	265	6	autoinflammatory	autoinflammatory	NNP
cord-003614-63rzzos3	265	7	CNS	CNS	NNP
cord-003614-63rzzos3	265	8	diseases	disease	NNS
cord-003614-63rzzos3	265	9	demonstrated	demonstrate	VBD
cord-003614-63rzzos3	265	10	that	that	IN
cord-003614-63rzzos3	265	11	they	-PRON-	PRP
cord-003614-63rzzos3	265	12	can	can	MD
cord-003614-63rzzos3	265	13	be	be	VB
cord-003614-63rzzos3	265	14	caused	cause	VBN
cord-003614-63rzzos3	265	15	by	by	IN
cord-003614-63rzzos3	265	16	an	an	DT
cord-003614-63rzzos3	265	17	uncontrolled	uncontrolled	JJ
cord-003614-63rzzos3	265	18	up	up	NN
cord-003614-63rzzos3	265	19	-	-	HYPH
cord-003614-63rzzos3	265	20	regulation	regulation	NN
cord-003614-63rzzos3	265	21	of	of	IN
cord-003614-63rzzos3	265	22	IFN	IFN	NNP
cord-003614-63rzzos3	265	23	-	-	:
cord-003614-63rzzos3	265	24	I	I	NNP
cord-003614-63rzzos3	265	25	signaling	signal	VBG
cord-003614-63rzzos3	265	26	and	and	CC
cord-003614-63rzzos3	265	27	JAK	JAK	NNP
cord-003614-63rzzos3	265	28	inhibition	inhibition	NN
cord-003614-63rzzos3	265	29	may	may	MD
cord-003614-63rzzos3	265	30	be	be	VB
cord-003614-63rzzos3	265	31	a	a	DT
cord-003614-63rzzos3	265	32	successful	successful	JJ
cord-003614-63rzzos3	265	33	therapeutic	therapeutic	JJ
cord-003614-63rzzos3	265	34	strategy	strategy	NN
cord-003614-63rzzos3	265	35	in	in	IN
cord-003614-63rzzos3	265	36	patients	patient	NNS
cord-003614-63rzzos3	265	37	with	with	IN
cord-003614-63rzzos3	265	38	these	these	DT
cord-003614-63rzzos3	265	39	type	type	NN
cord-003614-63rzzos3	266	1	I	-PRON-	PRP
cord-003614-63rzzos3	266	2	interferonopathies	interferonopathie	VBZ
cord-003614-63rzzos3	266	3	[	[	-LRB-
cord-003614-63rzzos3	266	4	121	121	CD
cord-003614-63rzzos3	266	5	]	]	-RRB-
cord-003614-63rzzos3	266	6	[	[	-LRB-
cord-003614-63rzzos3	266	7	122	122	CD
cord-003614-63rzzos3	266	8	]	]	-RRB-
cord-003614-63rzzos3	267	1	[	[	-LRB-
cord-003614-63rzzos3	267	2	123	123	CD
cord-003614-63rzzos3	267	3	]	]	-RRB-
cord-003614-63rzzos3	267	4	.	.	.
cord-003614-63rzzos3	268	1	Consequently	consequently	RB
cord-003614-63rzzos3	268	2	,	,	,
cord-003614-63rzzos3	268	3	the	the	DT
cord-003614-63rzzos3	268	4	strong	strong	JJ
cord-003614-63rzzos3	268	5	activation	activation	NN
cord-003614-63rzzos3	268	6	of	of	IN
cord-003614-63rzzos3	268	7	the	the	DT
cord-003614-63rzzos3	268	8	IFN	IFN	NNP
cord-003614-63rzzos3	268	9	-	-	HYPH
cord-003614-63rzzos3	268	10	I	I	NNP
cord-003614-63rzzos3	268	11	signaling	signal	VBG
cord-003614-63rzzos3	268	12	pathway	pathway	NN
cord-003614-63rzzos3	268	13	in	in	IN
cord-003614-63rzzos3	268	14	infiltrating	infiltrate	VBG
cord-003614-63rzzos3	268	15	immune	immune	JJ
cord-003614-63rzzos3	268	16	and	and	CC
cord-003614-63rzzos3	268	17	resident	resident	JJ
cord-003614-63rzzos3	268	18	CNS	CNS	NNP
cord-003614-63rzzos3	268	19	cells	cell	NNS
cord-003614-63rzzos3	268	20	including	include	VBG
cord-003614-63rzzos3	268	21	activated	activate	VBN
cord-003614-63rzzos3	268	22	microglia	microglia	NNS
cord-003614-63rzzos3	268	23	/	/	SYM
cord-003614-63rzzos3	268	24	macrophages	macrophage	NNS
cord-003614-63rzzos3	268	25	most	most	RBS
cord-003614-63rzzos3	268	26	likely	likely	RB
cord-003614-63rzzos3	268	27	contributes	contribute	VBZ
cord-003614-63rzzos3	268	28	to	to	IN
cord-003614-63rzzos3	268	29	immunopathological	immunopathological	JJ
cord-003614-63rzzos3	268	30	mechanisms	mechanism	NNS
cord-003614-63rzzos3	268	31	aggravating	aggravate	VBG
cord-003614-63rzzos3	268	32	CDV	CDV	NNP
cord-003614-63rzzos3	268	33	-	-	HYPH
cord-003614-63rzzos3	268	34	triggered	trigger	VBN
cord-003614-63rzzos3	268	35	demyelination	demyelination	NN
cord-003614-63rzzos3	268	36	.	.	.
cord-003614-63rzzos3	269	1	This	this	DT
cord-003614-63rzzos3	269	2	study	study	NN
cord-003614-63rzzos3	269	3	was	be	VBD
cord-003614-63rzzos3	269	4	conducted	conduct	VBN
cord-003614-63rzzos3	269	5	in	in	IN
cord-003614-63rzzos3	269	6	accordance	accordance	NN
cord-003614-63rzzos3	269	7	with	with	IN
cord-003614-63rzzos3	269	8	the	the	DT
cord-003614-63rzzos3	269	9	German	German	NNP
cord-003614-63rzzos3	269	10	Animal	Animal	NNP
cord-003614-63rzzos3	269	11	Welfare	Welfare	NNP
cord-003614-63rzzos3	269	12	Act	Act	NNP
cord-003614-63rzzos3	269	13	.	.	.
cord-003614-63rzzos3	270	1	All	all	DT
cord-003614-63rzzos3	270	2	animals	animal	NNS
cord-003614-63rzzos3	270	3	used	use	VBN
cord-003614-63rzzos3	270	4	in	in	IN
cord-003614-63rzzos3	270	5	this	this	DT
cord-003614-63rzzos3	270	6	study	study	NN
cord-003614-63rzzos3	270	7	were	be	VBD
cord-003614-63rzzos3	270	8	dead	dead	JJ
cord-003614-63rzzos3	270	9	at	at	IN
cord-003614-63rzzos3	270	10	the	the	DT
cord-003614-63rzzos3	270	11	time	time	NN
cord-003614-63rzzos3	270	12	of	of	IN
cord-003614-63rzzos3	270	13	submission	submission	NN
cord-003614-63rzzos3	270	14	for	for	IN
cord-003614-63rzzos3	270	15	necropsy	necropsy	JJ
cord-003614-63rzzos3	270	16	in	in	IN
cord-003614-63rzzos3	270	17	order	order	NN
cord-003614-63rzzos3	270	18	to	to	TO
cord-003614-63rzzos3	270	19	investigate	investigate	VB
cord-003614-63rzzos3	270	20	the	the	DT
cord-003614-63rzzos3	270	21	causes	cause	NNS
cord-003614-63rzzos3	270	22	of	of	IN
cord-003614-63rzzos3	270	23	death	death	NN
cord-003614-63rzzos3	270	24	and	and	CC
cord-003614-63rzzos3	270	25	disease	disease	NN
cord-003614-63rzzos3	270	26	.	.	.
cord-003614-63rzzos3	271	1	Consequently	consequently	RB
cord-003614-63rzzos3	271	2	,	,	,
cord-003614-63rzzos3	271	3	the	the	DT
cord-003614-63rzzos3	271	4	authors	author	NNS
cord-003614-63rzzos3	271	5	confirm	confirm	VBP
cord-003614-63rzzos3	271	6	that	that	IN
cord-003614-63rzzos3	271	7	this	this	DT
cord-003614-63rzzos3	271	8	study	study	NN
cord-003614-63rzzos3	271	9	does	do	VBZ
cord-003614-63rzzos3	271	10	not	not	RB
cord-003614-63rzzos3	271	11	contain	contain	VB
cord-003614-63rzzos3	271	12	data	datum	NNS
cord-003614-63rzzos3	271	13	obtained	obtain	VBN
cord-003614-63rzzos3	271	14	from	from	IN
cord-003614-63rzzos3	271	15	animal	animal	NN
cord-003614-63rzzos3	271	16	experiments	experiment	NNS
cord-003614-63rzzos3	271	17	and	and	CC
cord-003614-63rzzos3	271	18	no	no	DT
cord-003614-63rzzos3	271	19	animals	animal	NNS
cord-003614-63rzzos3	271	20	were	be	VBD
cord-003614-63rzzos3	271	21	infected	infect	VBN
cord-003614-63rzzos3	271	22	or	or	CC
cord-003614-63rzzos3	271	23	sacrificed	sacrifice	VBN
cord-003614-63rzzos3	271	24	for	for	IN
cord-003614-63rzzos3	271	25	the	the	DT
cord-003614-63rzzos3	271	26	purpose	purpose	NN
cord-003614-63rzzos3	271	27	of	of	IN
cord-003614-63rzzos3	271	28	this	this	DT
cord-003614-63rzzos3	271	29	retrospective	retrospective	JJ
cord-003614-63rzzos3	271	30	pathological	pathological	JJ
cord-003614-63rzzos3	271	31	case	case	NN
cord-003614-63rzzos3	271	32	-	-	HYPH
cord-003614-63rzzos3	271	33	control	control	NN
cord-003614-63rzzos3	271	34	study	study	NN
cord-003614-63rzzos3	271	35	.	.	.
cord-003614-63rzzos3	272	1	Moreover	moreover	RB
cord-003614-63rzzos3	272	2	,	,	,
cord-003614-63rzzos3	272	3	all	all	DT
cord-003614-63rzzos3	272	4	dog	dog	NN
cord-003614-63rzzos3	272	5	owners	owner	NNS
cord-003614-63rzzos3	272	6	provided	provide	VBD
cord-003614-63rzzos3	272	7	written	write	VBN
cord-003614-63rzzos3	272	8	consent	consent	NN
cord-003614-63rzzos3	272	9	for	for	IN
cord-003614-63rzzos3	272	10	the	the	DT
cord-003614-63rzzos3	272	11	dogs	dog	NNS
cord-003614-63rzzos3	272	12	'	'	POS
cord-003614-63rzzos3	272	13	tissues	tissue	NNS
cord-003614-63rzzos3	272	14	to	to	TO
cord-003614-63rzzos3	272	15	be	be	VB
cord-003614-63rzzos3	272	16	collected	collect	VBN
cord-003614-63rzzos3	272	17	and	and	CC
cord-003614-63rzzos3	272	18	used	use	VBN
cord-003614-63rzzos3	272	19	for	for	IN
cord-003614-63rzzos3	272	20	research	research	NN
cord-003614-63rzzos3	272	21	purposes	purpose	NNS
cord-003614-63rzzos3	272	22	.	.	.
cord-003614-63rzzos3	273	1	Paraffin	paraffin	NN
cord-003614-63rzzos3	273	2	-	-	HYPH
cord-003614-63rzzos3	273	3	embedded	embed	VBN
cord-003614-63rzzos3	273	4	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	273	5	tissue	tissue	NN
cord-003614-63rzzos3	273	6	of	of	IN
cord-003614-63rzzos3	273	7	15	15	CD
cord-003614-63rzzos3	273	8	naturally	naturally	RB
cord-003614-63rzzos3	273	9	CDV	CDV	NNP
cord-003614-63rzzos3	273	10	-	-	HYPH
cord-003614-63rzzos3	273	11	infected	infect	VBN
cord-003614-63rzzos3	273	12	dogs	dog	NNS
cord-003614-63rzzos3	273	13	and	and	CC
cord-003614-63rzzos3	273	14	six	six	CD
cord-003614-63rzzos3	273	15	control	control	NN
cord-003614-63rzzos3	273	16	dogs	dog	NNS
cord-003614-63rzzos3	273	17	without	without	IN
cord-003614-63rzzos3	273	18	any	any	DT
cord-003614-63rzzos3	273	19	CNS	CNS	NNP
cord-003614-63rzzos3	273	20	lesion	lesion	NN
cord-003614-63rzzos3	273	21	was	be	VBD
cord-003614-63rzzos3	273	22	collected	collect	VBN
cord-003614-63rzzos3	273	23	from	from	IN
cord-003614-63rzzos3	273	24	the	the	DT
cord-003614-63rzzos3	273	25	archive	archive	NN
cord-003614-63rzzos3	273	26	of	of	IN
cord-003614-63rzzos3	273	27	the	the	DT
cord-003614-63rzzos3	273	28	Department	Department	NNP
cord-003614-63rzzos3	273	29	of	of	IN
cord-003614-63rzzos3	273	30	Pathology	Pathology	NNP
cord-003614-63rzzos3	273	31	of	of	IN
cord-003614-63rzzos3	273	32	the	the	DT
cord-003614-63rzzos3	273	33	Veterinary	Veterinary	NNP
cord-003614-63rzzos3	273	34	University	University	NNP
cord-003614-63rzzos3	273	35	of	of	IN
cord-003614-63rzzos3	273	36	Hannover	Hannover	NNP
cord-003614-63rzzos3	273	37	,	,	,
cord-003614-63rzzos3	273	38	Germany	Germany	NNP
cord-003614-63rzzos3	273	39	and	and	CC
cord-003614-63rzzos3	273	40	used	use	VBN
cord-003614-63rzzos3	273	41	for	for	IN
cord-003614-63rzzos3	273	42	histological	histological	JJ
cord-003614-63rzzos3	273	43	analysis	analysis	NN
cord-003614-63rzzos3	273	44	and	and	CC
cord-003614-63rzzos3	273	45	immunostainings	immunostaining	NNS
cord-003614-63rzzos3	273	46	.	.	.
cord-003614-63rzzos3	274	1	Anamnestic	anamnestic	JJ
cord-003614-63rzzos3	274	2	data	datum	NNS
cord-003614-63rzzos3	274	3	of	of	IN
cord-003614-63rzzos3	274	4	the	the	DT
cord-003614-63rzzos3	274	5	investigated	investigate	VBN
cord-003614-63rzzos3	274	6	dogs	dog	NNS
cord-003614-63rzzos3	274	7	are	be	VBP
cord-003614-63rzzos3	274	8	summarized	summarize	VBN
cord-003614-63rzzos3	274	9	in	in	IN
cord-003614-63rzzos3	274	10	Table	Table	NNP
cord-003614-63rzzos3	274	11	S2	S2	NNP
cord-003614-63rzzos3	274	12	.	.	.
cord-003614-63rzzos3	275	1	Serial	serial	JJ
cord-003614-63rzzos3	275	2	two	two	CD
cord-003614-63rzzos3	275	3	-	-	HYPH
cord-003614-63rzzos3	275	4	micrometer	micrometer	NN
cord-003614-63rzzos3	275	5	paraffin	paraffin	NN
cord-003614-63rzzos3	275	6	sections	section	NNS
cord-003614-63rzzos3	275	7	were	be	VBD
cord-003614-63rzzos3	275	8	stained	stain	VBN
cord-003614-63rzzos3	275	9	with	with	IN
cord-003614-63rzzos3	275	10	hematoxylin	hematoxylin	NNP
cord-003614-63rzzos3	275	11	and	and	CC
cord-003614-63rzzos3	275	12	eosin	eosin	NNP
cord-003614-63rzzos3	275	13	(	(	-LRB-
cord-003614-63rzzos3	275	14	HE	HE	NNP
cord-003614-63rzzos3	275	15	)	)	-RRB-
cord-003614-63rzzos3	275	16	or	or	CC
cord-003614-63rzzos3	275	17	Luxol	Luxol	NNP
cord-003614-63rzzos3	275	18	fast	fast	JJ
cord-003614-63rzzos3	275	19	blue	blue	JJ
cord-003614-63rzzos3	275	20	(	(	-LRB-
cord-003614-63rzzos3	275	21	LFB	LFB	NNP
cord-003614-63rzzos3	275	22	)	)	-RRB-
cord-003614-63rzzos3	275	23	or	or	CC
cord-003614-63rzzos3	275	24	used	use	VBN
cord-003614-63rzzos3	275	25	for	for	IN
cord-003614-63rzzos3	275	26	immunohistochemistry	immunohistochemistry	NN
cord-003614-63rzzos3	275	27	.	.	.
cord-003614-63rzzos3	276	1	The	the	DT
cord-003614-63rzzos3	276	2	lesions	lesion	NNS
cord-003614-63rzzos3	276	3	in	in	IN
cord-003614-63rzzos3	276	4	the	the	DT
cord-003614-63rzzos3	276	5	CDV	CDV	NNP
cord-003614-63rzzos3	276	6	-	-	HYPH
cord-003614-63rzzos3	276	7	infected	infect	VBN
cord-003614-63rzzos3	276	8	dogs	dog	NNS
cord-003614-63rzzos3	276	9	were	be	VBD
cord-003614-63rzzos3	276	10	categorized	categorize	VBN
cord-003614-63rzzos3	276	11	with	with	IN
cord-003614-63rzzos3	276	12	HE	HE	NNP
cord-003614-63rzzos3	276	13	-	-	:
cord-003614-63rzzos3	276	14	and	and	CC
cord-003614-63rzzos3	276	15	LFB	LFB	NNP
cord-003614-63rzzos3	276	16	-	-	HYPH
cord-003614-63rzzos3	276	17	staining	stain	VBG
cord-003614-63rzzos3	276	18	as	as	IN
cord-003614-63rzzos3	276	19	previously	previously	RB
cord-003614-63rzzos3	276	20	described	describe	VBN
cord-003614-63rzzos3	276	21	[	[	-LRB-
cord-003614-63rzzos3	276	22	47	47	CD
cord-003614-63rzzos3	276	23	,	,	,
cord-003614-63rzzos3	276	24	106	106	CD
cord-003614-63rzzos3	276	25	,	,	,
cord-003614-63rzzos3	276	26	124	124	CD
cord-003614-63rzzos3	276	27	]	]	-RRB-
cord-003614-63rzzos3	276	28	.	.	.
cord-003614-63rzzos3	277	1	Briefly	briefly	RB
cord-003614-63rzzos3	277	2	,	,	,
cord-003614-63rzzos3	277	3	randomly	randomly	RB
cord-003614-63rzzos3	277	4	selected	select	VBN
cord-003614-63rzzos3	277	5	areas	area	NNS
cord-003614-63rzzos3	277	6	in	in	IN
cord-003614-63rzzos3	277	7	the	the	DT
cord-003614-63rzzos3	277	8	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	277	9	white	white	JJ
cord-003614-63rzzos3	277	10	matter	matter	NN
cord-003614-63rzzos3	277	11	of	of	IN
cord-003614-63rzzos3	277	12	dogs	dog	NNS
cord-003614-63rzzos3	277	13	without	without	IN
cord-003614-63rzzos3	277	14	any	any	DT
cord-003614-63rzzos3	277	15	lesions	lesion	NNS
cord-003614-63rzzos3	277	16	were	be	VBD
cord-003614-63rzzos3	277	17	used	use	VBN
cord-003614-63rzzos3	277	18	as	as	IN
cord-003614-63rzzos3	277	19	controls	control	NNS
cord-003614-63rzzos3	277	20	(	(	-LRB-
cord-003614-63rzzos3	277	21	group	group	NN
cord-003614-63rzzos3	277	22	1	1	CD
cord-003614-63rzzos3	277	23	)	)	-RRB-
cord-003614-63rzzos3	277	24	.	.	.
cord-003614-63rzzos3	278	1	White	white	JJ
cord-003614-63rzzos3	278	2	matter	matter	NN
cord-003614-63rzzos3	278	3	lesions	lesion	NNS
cord-003614-63rzzos3	278	4	of	of	IN
cord-003614-63rzzos3	278	5	CDV	CDV	NNP
cord-003614-63rzzos3	278	6	-	-	HYPH
cord-003614-63rzzos3	278	7	infected	infect	VBN
cord-003614-63rzzos3	278	8	dogs	dog	NNS
cord-003614-63rzzos3	278	9	were	be	VBD
cord-003614-63rzzos3	278	10	divided	divide	VBN
cord-003614-63rzzos3	278	11	into	into	IN
cord-003614-63rzzos3	278	12	four	four	CD
cord-003614-63rzzos3	278	13	groups	group	NNS
cord-003614-63rzzos3	278	14	.	.	.
cord-003614-63rzzos3	279	1	Group	group	NN
cord-003614-63rzzos3	279	2	2	2	CD
cord-003614-63rzzos3	279	3	(	(	-LRB-
cord-003614-63rzzos3	279	4	"	"	``
cord-003614-63rzzos3	279	5	antigen	antigen	NN
cord-003614-63rzzos3	279	6	without	without	IN
cord-003614-63rzzos3	279	7	lesion	lesion	NN
cord-003614-63rzzos3	279	8	"	"	''
cord-003614-63rzzos3	279	9	)	)	-RRB-
cord-003614-63rzzos3	279	10	included	include	VBD
cord-003614-63rzzos3	279	11	areas	area	NNS
cord-003614-63rzzos3	279	12	with	with	IN
cord-003614-63rzzos3	279	13	antigen	antigen	NN
cord-003614-63rzzos3	279	14	expression	expression	NN
cord-003614-63rzzos3	279	15	but	but	CC
cord-003614-63rzzos3	279	16	with	with	IN
cord-003614-63rzzos3	279	17	no	no	DT
cord-003614-63rzzos3	279	18	lesions	lesion	NNS
cord-003614-63rzzos3	279	19	in	in	IN
cord-003614-63rzzos3	279	20	HE	HE	NNP
cord-003614-63rzzos3	279	21	-	-	:
cord-003614-63rzzos3	279	22	or	or	CC
cord-003614-63rzzos3	279	23	LFB	LFB	NNP
cord-003614-63rzzos3	279	24	-	-	HYPH
cord-003614-63rzzos3	279	25	stainings	staining	NNS
cord-003614-63rzzos3	279	26	.	.	.
cord-003614-63rzzos3	280	1	Group	group	NN
cord-003614-63rzzos3	280	2	3	3	CD
cord-003614-63rzzos3	280	3	lesions	lesion	NNS
cord-003614-63rzzos3	280	4	(	(	-LRB-
cord-003614-63rzzos3	280	5	"	"	``
cord-003614-63rzzos3	280	6	acute	acute	JJ
cord-003614-63rzzos3	280	7	"	"	''
cord-003614-63rzzos3	280	8	)	)	-RRB-
cord-003614-63rzzos3	280	9	were	be	VBD
cord-003614-63rzzos3	280	10	characterized	characterize	VBN
cord-003614-63rzzos3	280	11	by	by	IN
cord-003614-63rzzos3	280	12	vacuolation	vacuolation	NN
cord-003614-63rzzos3	280	13	in	in	IN
cord-003614-63rzzos3	280	14	the	the	DT
cord-003614-63rzzos3	280	15	HE	HE	NNP
cord-003614-63rzzos3	280	16	staining	staining	NN
cord-003614-63rzzos3	280	17	and	and	CC
cord-003614-63rzzos3	280	18	absence	absence	NN
cord-003614-63rzzos3	280	19	of	of	IN
cord-003614-63rzzos3	280	20	demyelination	demyelination	NN
cord-003614-63rzzos3	280	21	in	in	IN
cord-003614-63rzzos3	280	22	the	the	DT
cord-003614-63rzzos3	280	23	LFB	LFB	NNP
cord-003614-63rzzos3	280	24	-	-	HYPH
cord-003614-63rzzos3	280	25	staining	staining	NN
cord-003614-63rzzos3	280	26	.	.	.
cord-003614-63rzzos3	281	1	Group	group	NN
cord-003614-63rzzos3	281	2	4	4	CD
cord-003614-63rzzos3	281	3	(	(	-LRB-
cord-003614-63rzzos3	281	4	"	"	``
cord-003614-63rzzos3	281	5	subacute	subacute	JJ
cord-003614-63rzzos3	281	6	"	"	''
cord-003614-63rzzos3	281	7	)	)	-RRB-
cord-003614-63rzzos3	281	8	included	include	VBD
cord-003614-63rzzos3	281	9	lesions	lesion	NNS
cord-003614-63rzzos3	281	10	with	with	IN
cord-003614-63rzzos3	281	11	demyelination	demyelination	NN
cord-003614-63rzzos3	281	12	but	but	CC
cord-003614-63rzzos3	281	13	with	with	IN
cord-003614-63rzzos3	281	14	no	no	DT
cord-003614-63rzzos3	281	15	inflammatory	inflammatory	JJ
cord-003614-63rzzos3	281	16	infiltrates	infiltrate	VBZ
cord-003614-63rzzos3	281	17	in	in	IN
cord-003614-63rzzos3	281	18	the	the	DT
cord-003614-63rzzos3	281	19	HE	HE	NNP
cord-003614-63rzzos3	281	20	-	-	HYPH
cord-003614-63rzzos3	281	21	staining	stain	VBG
cord-003614-63rzzos3	281	22	.	.	.
cord-003614-63rzzos3	282	1	Group	group	NN
cord-003614-63rzzos3	282	2	5	5	CD
cord-003614-63rzzos3	282	3	(	(	-LRB-
cord-003614-63rzzos3	282	4	"	"	``
cord-003614-63rzzos3	282	5	chronic	chronic	JJ
cord-003614-63rzzos3	282	6	"	"	''
cord-003614-63rzzos3	282	7	)	)	-RRB-
cord-003614-63rzzos3	282	8	contained	contain	VBD
cord-003614-63rzzos3	282	9	demyelinated	demyelinate	VBN
cord-003614-63rzzos3	282	10	lesions	lesion	NNS
cord-003614-63rzzos3	282	11	with	with	IN
cord-003614-63rzzos3	282	12	variable	variable	JJ
cord-003614-63rzzos3	282	13	numbers	number	NNS
cord-003614-63rzzos3	282	14	of	of	IN
cord-003614-63rzzos3	282	15	inflammatory	inflammatory	JJ
cord-003614-63rzzos3	282	16	cells	cell	NNS
cord-003614-63rzzos3	282	17	in	in	IN
cord-003614-63rzzos3	282	18	the	the	DT
cord-003614-63rzzos3	282	19	perivascular	perivascular	JJ
cord-003614-63rzzos3	282	20	area	area	NN
cord-003614-63rzzos3	282	21	or	or	CC
cord-003614-63rzzos3	282	22	diffusely	diffusely	RB
cord-003614-63rzzos3	282	23	distributed	distribute	VBN
cord-003614-63rzzos3	282	24	ones	one	NNS
cord-003614-63rzzos3	282	25	in	in	IN
cord-003614-63rzzos3	282	26	the	the	DT
cord-003614-63rzzos3	282	27	parenchyma	parenchyma	NN
cord-003614-63rzzos3	282	28	.	.	.
cord-003614-63rzzos3	283	1	An	an	DT
cord-003614-63rzzos3	283	2	MIAME	MIAME	NNP
cord-003614-63rzzos3	283	3	-	-	HYPH
cord-003614-63rzzos3	283	4	compliant	compliant	JJ
cord-003614-63rzzos3	283	5	expression	expression	NN
cord-003614-63rzzos3	283	6	raw	raw	JJ
cord-003614-63rzzos3	283	7	data	datum	NNS
cord-003614-63rzzos3	283	8	set	set	VBN
cord-003614-63rzzos3	283	9	of	of	IN
cord-003614-63rzzos3	283	10	a	a	DT
cord-003614-63rzzos3	283	11	previously	previously	RB
cord-003614-63rzzos3	283	12	published	publish	VBN
cord-003614-63rzzos3	283	13	microarray	microarray	NN
cord-003614-63rzzos3	283	14	study	study	NN
cord-003614-63rzzos3	283	15	upon	upon	IN
cord-003614-63rzzos3	283	16	CDV	CDV	NNP
cord-003614-63rzzos3	283	17	-	-	HYPH
cord-003614-63rzzos3	283	18	induced	induce	VBN
cord-003614-63rzzos3	283	19	demyelinating	demyelinate	VBG
cord-003614-63rzzos3	283	20	leukoencephalitis	leukoencephalitis	NNP
cord-003614-63rzzos3	283	21	performed	perform	VBN
cord-003614-63rzzos3	283	22	on	on	IN
cord-003614-63rzzos3	283	23	GeneChip	GeneChip	NNP
cord-003614-63rzzos3	283	24	canine	canine	JJ
cord-003614-63rzzos3	283	25	genome	genome	NN
cord-003614-63rzzos3	283	26	2.0	2.0	CD
cord-003614-63rzzos3	283	27	arrays	array	NNS
cord-003614-63rzzos3	284	1	(	(	-LRB-
cord-003614-63rzzos3	284	2	Affymetrix	Affymetrix	NNP
cord-003614-63rzzos3	284	3	Inc.	Inc.	NNP
cord-003614-63rzzos3	284	4	,	,	,
cord-003614-63rzzos3	284	5	Santa	Santa	NNP
cord-003614-63rzzos3	284	6	Clara	Clara	NNP
cord-003614-63rzzos3	284	7	,	,	,
cord-003614-63rzzos3	284	8	USA	USA	NNP
cord-003614-63rzzos3	284	9	)	)	-RRB-
cord-003614-63rzzos3	284	10	was	be	VBD
cord-003614-63rzzos3	284	11	accessed	access	VBN
cord-003614-63rzzos3	284	12	via	via	IN
cord-003614-63rzzos3	284	13	the	the	DT
cord-003614-63rzzos3	284	14	ArrayExpress	ArrayExpress	NNP
cord-003614-63rzzos3	284	15	database	database	NN
cord-003614-63rzzos3	284	16	(	(	-LRB-
cord-003614-63rzzos3	284	17	accession	accession	NN
cord-003614-63rzzos3	284	18	number	number	NN
cord-003614-63rzzos3	284	19	:	:	:
cord-003614-63rzzos3	284	20	E	E	NNP
cord-003614-63rzzos3	284	21	-	-	HYPH
cord-003614-63rzzos3	284	22	MEXP-3917	MEXP-3917	NNS
cord-003614-63rzzos3	284	23	;	;	:
cord-003614-63rzzos3	284	24	http://www.ebi.ac.uk/arrayexpress	http://www.ebi.ac.uk/arrayexpress	ADD
cord-003614-63rzzos3	284	25	)	)	-RRB-
cord-003614-63rzzos3	285	1	[	[	-LRB-
cord-003614-63rzzos3	285	2	47	47	CD
cord-003614-63rzzos3	285	3	]	]	-RRB-
cord-003614-63rzzos3	285	4	.	.	.
cord-003614-63rzzos3	286	1	RNA	RNA	NNP
cord-003614-63rzzos3	286	2	used	use	VBN
cord-003614-63rzzos3	286	3	for	for	IN
cord-003614-63rzzos3	286	4	the	the	DT
cord-003614-63rzzos3	286	5	original	original	JJ
cord-003614-63rzzos3	286	6	microarray	microarray	NN
cord-003614-63rzzos3	286	7	study	study	NN
cord-003614-63rzzos3	286	8	was	be	VBD
cord-003614-63rzzos3	286	9	isolated	isolate	VBN
cord-003614-63rzzos3	286	10	from	from	IN
cord-003614-63rzzos3	286	11	frozen	frozen	JJ
cord-003614-63rzzos3	286	12	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	286	13	specimens	specimen	NNS
cord-003614-63rzzos3	286	14	of	of	IN
cord-003614-63rzzos3	286	15	12	12	CD
cord-003614-63rzzos3	286	16	control	control	NN
cord-003614-63rzzos3	286	17	dogs	dog	NNS
cord-003614-63rzzos3	286	18	and	and	CC
cord-003614-63rzzos3	286	19	14	14	CD
cord-003614-63rzzos3	286	20	CDV	CDV	NNP
cord-003614-63rzzos3	286	21	-	-	HYPH
cord-003614-63rzzos3	286	22	infected	infect	VBN
cord-003614-63rzzos3	286	23	dogs	dog	NNS
cord-003614-63rzzos3	286	24	,	,	,
cord-003614-63rzzos3	286	25	which	which	WDT
cord-003614-63rzzos3	286	26	were	be	VBD
cord-003614-63rzzos3	286	27	grouped	group	VBN
cord-003614-63rzzos3	286	28	using	use	VBG
cord-003614-63rzzos3	286	29	a	a	DT
cord-003614-63rzzos3	286	30	classification	classification	NN
cord-003614-63rzzos3	286	31	system	system	NN
cord-003614-63rzzos3	286	32	similar	similar	JJ
cord-003614-63rzzos3	286	33	to	to	IN
cord-003614-63rzzos3	286	34	the	the	DT
cord-003614-63rzzos3	286	35	present	present	JJ
cord-003614-63rzzos3	286	36	study	study	NN
cord-003614-63rzzos3	286	37	(	(	-LRB-
cord-003614-63rzzos3	286	38	control	control	NN
cord-003614-63rzzos3	286	39	;	;	:
cord-003614-63rzzos3	286	40	acute	acute	JJ
cord-003614-63rzzos3	286	41	;	;	:
cord-003614-63rzzos3	286	42	subacute	subacute	JJ
cord-003614-63rzzos3	286	43	;	;	:
cord-003614-63rzzos3	286	44	chronic	chronic	JJ
cord-003614-63rzzos3	286	45	)	)	-RRB-
cord-003614-63rzzos3	286	46	[	[	-LRB-
cord-003614-63rzzos3	286	47	47	47	CD
cord-003614-63rzzos3	286	48	]	]	-RRB-
cord-003614-63rzzos3	286	49	.	.	.
cord-003614-63rzzos3	287	1	Fold	fold	VB
cord-003614-63rzzos3	287	2	changes	change	NNS
cord-003614-63rzzos3	287	3	in	in	IN
cord-003614-63rzzos3	287	4	this	this	DT
cord-003614-63rzzos3	287	5	data	data	NN
cord-003614-63rzzos3	287	6	set	set	VBN
cord-003614-63rzzos3	287	7	were	be	VBD
cord-003614-63rzzos3	287	8	calculated	calculate	VBN
cord-003614-63rzzos3	287	9	as	as	IN
cord-003614-63rzzos3	287	10	the	the	DT
cord-003614-63rzzos3	287	11	ratio	ratio	NN
cord-003614-63rzzos3	287	12	of	of	IN
cord-003614-63rzzos3	287	13	the	the	DT
cord-003614-63rzzos3	287	14	inverse	inverse	NN
cord-003614-63rzzos3	287	15	-	-	HYPH
cord-003614-63rzzos3	287	16	transformed	transform	VBN
cord-003614-63rzzos3	287	17	arithmetic	arithmetic	JJ
cord-003614-63rzzos3	287	18	means	mean	NNS
cord-003614-63rzzos3	287	19	of	of	IN
cord-003614-63rzzos3	287	20	the	the	DT
cord-003614-63rzzos3	287	21	log2-transformed	log2-transformed	JJ
cord-003614-63rzzos3	287	22	expression	expression	NN
cord-003614-63rzzos3	287	23	values	value	NNS
cord-003614-63rzzos3	287	24	between	between	IN
cord-003614-63rzzos3	287	25	the	the	DT
cord-003614-63rzzos3	287	26	respective	respective	JJ
cord-003614-63rzzos3	287	27	groups	group	NNS
cord-003614-63rzzos3	287	28	.	.	.
cord-003614-63rzzos3	288	1	Downregulations	downregulation	NNS
cord-003614-63rzzos3	288	2	are	be	VBP
cord-003614-63rzzos3	288	3	given	give	VBN
cord-003614-63rzzos3	288	4	as	as	IN
cord-003614-63rzzos3	288	5	negative	negative	JJ
cord-003614-63rzzos3	288	6	reciprocal	reciprocal	JJ
cord-003614-63rzzos3	288	7	values	value	NNS
cord-003614-63rzzos3	288	8	[	[	-LRB-
cord-003614-63rzzos3	288	9	47	47	CD
cord-003614-63rzzos3	288	10	]	]	-RRB-
cord-003614-63rzzos3	288	11	.	.	.
cord-003614-63rzzos3	289	1	In	in	IN
cord-003614-63rzzos3	289	2	order	order	NN
cord-003614-63rzzos3	289	3	to	to	TO
cord-003614-63rzzos3	289	4	perform	perform	VB
cord-003614-63rzzos3	289	5	a	a	DT
cord-003614-63rzzos3	289	6	bottom	bottom	NN
cord-003614-63rzzos3	289	7	-	-	HYPH
cord-003614-63rzzos3	289	8	up	up	NN
cord-003614-63rzzos3	289	9	analysis	analysis	NN
cord-003614-63rzzos3	289	10	of	of	IN
cord-003614-63rzzos3	289	11	transcriptional	transcriptional	JJ
cord-003614-63rzzos3	289	12	changes	change	NNS
cord-003614-63rzzos3	289	13	in	in	IN
cord-003614-63rzzos3	289	14	CDV	CDV	NNP
cord-003614-63rzzos3	289	15	-	-	HYPH
cord-003614-63rzzos3	289	16	induced	induce	VBN
cord-003614-63rzzos3	289	17	lesions	lesion	NNS
cord-003614-63rzzos3	289	18	,	,	,
cord-003614-63rzzos3	289	19	110	110	CD
cord-003614-63rzzos3	289	20	candidate	candidate	NN
cord-003614-63rzzos3	289	21	genes	gene	NNS
cord-003614-63rzzos3	289	22	including	include	VBG
cord-003614-63rzzos3	289	23	12	12	CD
cord-003614-63rzzos3	289	24	pattern	pattern	NN
cord-003614-63rzzos3	289	25	recognition	recognition	NN
cord-003614-63rzzos3	289	26	receptors	receptor	NNS
cord-003614-63rzzos3	289	27	(	(	-LRB-
cord-003614-63rzzos3	289	28	PRRs	PRRs	NNP
cord-003614-63rzzos3	289	29	)	)	-RRB-
cord-003614-63rzzos3	289	30	,	,	,
cord-003614-63rzzos3	289	31	ten	ten	CD
cord-003614-63rzzos3	289	32	IFN	IFN	NNP
cord-003614-63rzzos3	289	33	regulatory	regulatory	JJ
cord-003614-63rzzos3	289	34	factors	factor	NNS
cord-003614-63rzzos3	289	35	,	,	,
cord-003614-63rzzos3	289	36	eight	eight	CD
cord-003614-63rzzos3	289	37	type	type	NN
cord-003614-63rzzos3	289	38	I	I	NNP
cord-003614-63rzzos3	289	39	/	/	SYM
cord-003614-63rzzos3	289	40	II	II	NNP
cord-003614-63rzzos3	289	41	IFNs	ifn	NNS
cord-003614-63rzzos3	289	42	,	,	,
cord-003614-63rzzos3	289	43	five	five	CD
cord-003614-63rzzos3	289	44	type	type	NN
cord-003614-63rzzos3	289	45	I	I	NNP
cord-003614-63rzzos3	289	46	/	/	SYM
cord-003614-63rzzos3	289	47	II	II	NNP
cord-003614-63rzzos3	289	48	/	/	SYM
cord-003614-63rzzos3	289	49	III	iii	CD
cord-003614-63rzzos3	289	50	receptors	receptor	NNS
cord-003614-63rzzos3	289	51	,	,	,
cord-003614-63rzzos3	289	52	17	17	CD
cord-003614-63rzzos3	289	53	signal	signal	NN
cord-003614-63rzzos3	289	54	transducers	transducer	NNS
cord-003614-63rzzos3	289	55	,	,	,
cord-003614-63rzzos3	289	56	46	46	CD
cord-003614-63rzzos3	289	57	IFN	IFN	NNP
cord-003614-63rzzos3	289	58	-	-	HYPH
cord-003614-63rzzos3	289	59	dependent	dependent	JJ
cord-003614-63rzzos3	289	60	antiviral	antiviral	JJ
cord-003614-63rzzos3	289	61	effectors	effector	NNS
cord-003614-63rzzos3	289	62	and	and	CC
cord-003614-63rzzos3	289	63	12	12	CD
cord-003614-63rzzos3	289	64	MHC	MHC	NNP
cord-003614-63rzzos3	289	65	class	class	NN
cord-003614-63rzzos3	289	66	I	i	NN
cord-003614-63rzzos3	289	67	/	/	SYM
cord-003614-63rzzos3	289	68	II	II	NNP
cord-003614-63rzzos3	289	69	genes	gene	NNS
cord-003614-63rzzos3	289	70	were	be	VBD
cord-003614-63rzzos3	289	71	manually	manually	RB
cord-003614-63rzzos3	289	72	extracted	extract	VBN
cord-003614-63rzzos3	289	73	from	from	IN
cord-003614-63rzzos3	289	74	peer	peer	NN
cord-003614-63rzzos3	289	75	-	-	HYPH
cord-003614-63rzzos3	289	76	reviewed	review	VBN
cord-003614-63rzzos3	289	77	published	publish	VBN
cord-003614-63rzzos3	289	78	literature	literature	NN
cord-003614-63rzzos3	289	79	(	(	-LRB-
cord-003614-63rzzos3	289	80	Table	Table	NNP
cord-003614-63rzzos3	289	81	S1	S1	NNP
cord-003614-63rzzos3	289	82	)	)	-RRB-
cord-003614-63rzzos3	289	83	[	[	-LRB-
cord-003614-63rzzos3	289	84	12	12	CD
cord-003614-63rzzos3	289	85	,	,	,
cord-003614-63rzzos3	289	86	30	30	CD
cord-003614-63rzzos3	289	87	,	,	,
cord-003614-63rzzos3	289	88	62	62	CD
cord-003614-63rzzos3	289	89	,	,	,
cord-003614-63rzzos3	289	90	125	125	CD
cord-003614-63rzzos3	289	91	,	,	,
cord-003614-63rzzos3	289	92	126	126	CD
cord-003614-63rzzos3	289	93	]	]	-RRB-
cord-003614-63rzzos3	289	94	.	.	.
cord-003614-63rzzos3	290	1	If	if	IN
cord-003614-63rzzos3	290	2	necessary	necessary	JJ
cord-003614-63rzzos3	290	3	,	,	,
cord-003614-63rzzos3	290	4	murine	murine	JJ
cord-003614-63rzzos3	290	5	and	and	CC
cord-003614-63rzzos3	290	6	human	human	JJ
cord-003614-63rzzos3	290	7	genes	gene	NNS
cord-003614-63rzzos3	290	8	were	be	VBD
cord-003614-63rzzos3	290	9	converted	convert	VBN
cord-003614-63rzzos3	290	10	into	into	IN
cord-003614-63rzzos3	290	11	orthologous	orthologous	JJ
cord-003614-63rzzos3	290	12	canine	canine	JJ
cord-003614-63rzzos3	290	13	gene	gene	NN
cord-003614-63rzzos3	290	14	symbols	symbol	NNS
cord-003614-63rzzos3	290	15	using	use	VBG
cord-003614-63rzzos3	290	16	the	the	DT
cord-003614-63rzzos3	290	17	MADGene	MADGene	NNP
cord-003614-63rzzos3	290	18	web	web	NN
cord-003614-63rzzos3	290	19	tool	tool	NN
cord-003614-63rzzos3	290	20	(	(	-LRB-
cord-003614-63rzzos3	290	21	http	http	NNP
cord-003614-63rzzos3	290	22	:	:	:
cord-003614-63rzzos3	290	23	//cardioserve.nantes.inserm.fr	//cardioserve.nantes.inserm.fr	NNP
cord-003614-63rzzos3	290	24	/	/	SYM
cord-003614-63rzzos3	290	25	madtools	madtool	NNS
cord-003614-63rzzos3	290	26	/	/	SYM
cord-003614-63rzzos3	290	27	madgene/	madgene/	CD
cord-003614-63rzzos3	290	28	)	)	-RRB-
cord-003614-63rzzos3	290	29	[	[	-LRB-
cord-003614-63rzzos3	290	30	127	127	CD
cord-003614-63rzzos3	290	31	]	]	-RRB-
cord-003614-63rzzos3	290	32	.	.	.
cord-003614-63rzzos3	291	1	The	the	DT
cord-003614-63rzzos3	291	2	expression	expression	NN
cord-003614-63rzzos3	291	3	values	value	NNS
cord-003614-63rzzos3	291	4	of	of	IN
cord-003614-63rzzos3	291	5	these	these	DT
cord-003614-63rzzos3	291	6	genes	gene	NNS
cord-003614-63rzzos3	291	7	were	be	VBD
cord-003614-63rzzos3	291	8	evaluated	evaluate	VBN
cord-003614-63rzzos3	291	9	for	for	IN
cord-003614-63rzzos3	291	10	significant	significant	JJ
cord-003614-63rzzos3	291	11	differences	difference	NNS
cord-003614-63rzzos3	291	12	between	between	IN
cord-003614-63rzzos3	291	13	the	the	DT
cord-003614-63rzzos3	291	14	respective	respective	JJ
cord-003614-63rzzos3	291	15	groups	group	NNS
cord-003614-63rzzos3	291	16	employing	employ	VBG
cord-003614-63rzzos3	291	17	independent	independent	JJ
cord-003614-63rzzos3	291	18	pairwise	pairwise	JJ
cord-003614-63rzzos3	291	19	Mann	Mann	NNP
cord-003614-63rzzos3	291	20	-	-	HYPH
cord-003614-63rzzos3	291	21	Whitney	Whitney	NNP
cord-003614-63rzzos3	291	22	U	U	NNP
cord-003614-63rzzos3	291	23	tests	test	NNS
cord-003614-63rzzos3	291	24	(	(	-LRB-
cord-003614-63rzzos3	291	25	see	see	VB
cord-003614-63rzzos3	291	26	statistical	statistical	JJ
cord-003614-63rzzos3	291	27	analysis	analysis	NN
cord-003614-63rzzos3	291	28	)	)	-RRB-
cord-003614-63rzzos3	291	29	.	.	.
cord-003614-63rzzos3	292	1	For	for	IN
cord-003614-63rzzos3	292	2	immunohistochemistry	immunohistochemistry	NN
cord-003614-63rzzos3	292	3	,	,	,
cord-003614-63rzzos3	292	4	sections	section	NNS
cord-003614-63rzzos3	292	5	were	be	VBD
cord-003614-63rzzos3	292	6	dewaxed	dewaxe	VBN
cord-003614-63rzzos3	292	7	,	,	,
cord-003614-63rzzos3	292	8	rehydrated	rehydrate	VBN
cord-003614-63rzzos3	292	9	and	and	CC
cord-003614-63rzzos3	292	10	incubated	incubate	VBN
cord-003614-63rzzos3	292	11	in	in	IN
cord-003614-63rzzos3	292	12	ethanol	ethanol	NN
cord-003614-63rzzos3	292	13	with	with	IN
cord-003614-63rzzos3	292	14	0.5	0.5	CD
cord-003614-63rzzos3	292	15	%	%	NN
cord-003614-63rzzos3	292	16	hydrogen	hydrogen	NN
cord-003614-63rzzos3	292	17	peroxide	peroxide	NN
cord-003614-63rzzos3	292	18	for	for	IN
cord-003614-63rzzos3	292	19	30	30	CD
cord-003614-63rzzos3	292	20	min	min	NN
cord-003614-63rzzos3	292	21	to	to	TO
cord-003614-63rzzos3	292	22	block	block	VB
cord-003614-63rzzos3	292	23	endogenous	endogenous	JJ
cord-003614-63rzzos3	292	24	peroxidase	peroxidase	NN
cord-003614-63rzzos3	292	25	.	.	.
cord-003614-63rzzos3	293	1	Except	except	IN
cord-003614-63rzzos3	293	2	for	for	IN
cord-003614-63rzzos3	293	3	STAT1	stat1	NN
cord-003614-63rzzos3	293	4	,	,	,
cord-003614-63rzzos3	293	5	sections	section	NNS
cord-003614-63rzzos3	293	6	were	be	VBD
cord-003614-63rzzos3	293	7	pretreated	pretreate	VBN
cord-003614-63rzzos3	293	8	by	by	IN
cord-003614-63rzzos3	293	9	boiling	boil	VBG
cord-003614-63rzzos3	293	10	them	-PRON-	PRP
cord-003614-63rzzos3	293	11	in	in	IN
cord-003614-63rzzos3	293	12	10	10	CD
cord-003614-63rzzos3	293	13	mM	mm	CD
cord-003614-63rzzos3	293	14	sodium	sodium	NN
cord-003614-63rzzos3	293	15	citrate	citrate	NN
cord-003614-63rzzos3	293	16	buffer	buffer	NN
cord-003614-63rzzos3	293	17	(	(	-LRB-
cord-003614-63rzzos3	293	18	pH	pH	NNP
cord-003614-63rzzos3	293	19	6	6	CD
cord-003614-63rzzos3	293	20	)	)	-RRB-
cord-003614-63rzzos3	293	21	for	for	IN
cord-003614-63rzzos3	293	22	20	20	CD
cord-003614-63rzzos3	293	23	min	min	NN
cord-003614-63rzzos3	293	24	in	in	IN
cord-003614-63rzzos3	293	25	a	a	DT
cord-003614-63rzzos3	293	26	microwave	microwave	NN
cord-003614-63rzzos3	293	27	oven	oven	NN
cord-003614-63rzzos3	293	28	(	(	-LRB-
cord-003614-63rzzos3	293	29	800	800	CD
cord-003614-63rzzos3	293	30	W	W	NNP
cord-003614-63rzzos3	293	31	)	)	-RRB-
cord-003614-63rzzos3	293	32	.	.	.
cord-003614-63rzzos3	294	1	Sections	section	NNS
cord-003614-63rzzos3	294	2	were	be	VBD
cord-003614-63rzzos3	294	3	blocked	block	VBN
cord-003614-63rzzos3	294	4	with	with	IN
cord-003614-63rzzos3	294	5	phosphate	phosphate	NN
cord-003614-63rzzos3	294	6	-	-	HYPH
cord-003614-63rzzos3	294	7	buffered	buffer	VBN
cord-003614-63rzzos3	294	8	saline	saline	NN
cord-003614-63rzzos3	294	9	(	(	-LRB-
cord-003614-63rzzos3	294	10	PBS	PBS	NNP
cord-003614-63rzzos3	294	11	)	)	-RRB-
cord-003614-63rzzos3	294	12	containing	contain	VBG
cord-003614-63rzzos3	294	13	20	20	CD
cord-003614-63rzzos3	294	14	%	%	NN
cord-003614-63rzzos3	294	15	goat	goat	NN
cord-003614-63rzzos3	294	16	serum	serum	NN
cord-003614-63rzzos3	294	17	for	for	IN
cord-003614-63rzzos3	294	18	30	30	CD
cord-003614-63rzzos3	294	19	min	min	NN
cord-003614-63rzzos3	294	20	at	at	IN
cord-003614-63rzzos3	294	21	room	room	NN
cord-003614-63rzzos3	294	22	temperature	temperature	NN
cord-003614-63rzzos3	294	23	and	and	CC
cord-003614-63rzzos3	294	24	incubated	incubate	VBN
cord-003614-63rzzos3	294	25	with	with	IN
cord-003614-63rzzos3	294	26	rabbit	rabbit	NN
cord-003614-63rzzos3	294	27	polyclonal	polyclonal	JJ
cord-003614-63rzzos3	294	28	anti	anti	JJ
cord-003614-63rzzos3	294	29	-	-	JJ
cord-003614-63rzzos3	294	30	phosphorylated	phosphorylated	JJ
cord-003614-63rzzos3	295	1	STAT1	STAT1	NNP
cord-003614-63rzzos3	295	2	(	(	-LRB-
cord-003614-63rzzos3	295	3	p84	p84	CD
cord-003614-63rzzos3	295	4	/	/	SYM
cord-003614-63rzzos3	295	5	p91	p91	NN
cord-003614-63rzzos3	295	6	,	,	,
cord-003614-63rzzos3	295	7	sc-346	sc-346	NN
cord-003614-63rzzos3	295	8	,	,	,
cord-003614-63rzzos3	295	9	Santa	Santa	NNP
cord-003614-63rzzos3	295	10	Cruz	Cruz	NNP
cord-003614-63rzzos3	295	11	Biotechnology	Biotechnology	NNP
cord-003614-63rzzos3	295	12	Inc.	Inc.	NNP
cord-003614-63rzzos3	295	13	,	,	,
cord-003614-63rzzos3	295	14	Santa	Santa	NNP
cord-003614-63rzzos3	295	15	Cruz	Cruz	NNP
cord-003614-63rzzos3	295	16	,	,	,
cord-003614-63rzzos3	295	17	CA	CA	NNP
cord-003614-63rzzos3	295	18	,	,	,
cord-003614-63rzzos3	295	19	USA	USA	NNP
cord-003614-63rzzos3	295	20	,	,	,
cord-003614-63rzzos3	295	21	1:400	1:400	CD
cord-003614-63rzzos3	295	22	)	)	-RRB-
cord-003614-63rzzos3	295	23	,	,	,
cord-003614-63rzzos3	295	24	anti	anti	NNP
cord-003614-63rzzos3	295	25	-	-	NNP
cord-003614-63rzzos3	295	26	OAS	OAS	NNP
cord-003614-63rzzos3	296	1	(	(	-LRB-
cord-003614-63rzzos3	296	2	sc-98424	sc-98424	NNP
cord-003614-63rzzos3	296	3	,	,	,
cord-003614-63rzzos3	296	4	Santa	Santa	NNP
cord-003614-63rzzos3	296	5	Cruz	Cruz	NNP
cord-003614-63rzzos3	296	6	,	,	,
cord-003614-63rzzos3	296	7	1:600	1:600	CD
cord-003614-63rzzos3	296	8	)	)	-RRB-
cord-003614-63rzzos3	296	9	and	and	CC
cord-003614-63rzzos3	296	10	anti	anti	JJ
cord-003614-63rzzos3	296	11	-	-	JJ
cord-003614-63rzzos3	296	12	ISG15	isg15	JJ
cord-003614-63rzzos3	297	1	(	(	-LRB-
cord-003614-63rzzos3	297	2	sc-50366	sc-50366	NNS
cord-003614-63rzzos3	297	3	,	,	,
cord-003614-63rzzos3	297	4	Santa	Santa	NNP
cord-003614-63rzzos3	297	5	Cruz	Cruz	NNP
cord-003614-63rzzos3	297	6	,	,	,
cord-003614-63rzzos3	297	7	1:600	1:600	CD
cord-003614-63rzzos3	297	8	)	)	-RRB-
cord-003614-63rzzos3	297	9	,	,	,
cord-003614-63rzzos3	297	10	rabbit	rabbit	NN
cord-003614-63rzzos3	297	11	monoclonal	monoclonal	JJ
cord-003614-63rzzos3	297	12	anti	anti	NNP
cord-003614-63rzzos3	297	13	-	-	NNP
cord-003614-63rzzos3	297	14	IRF3	IRF3	NNP
cord-003614-63rzzos3	298	1	(	(	-LRB-
cord-003614-63rzzos3	298	2	ab68481	ab68481	NNP
cord-003614-63rzzos3	298	3	,	,	,
cord-003614-63rzzos3	298	4	Abcam	Abcam	NNP
cord-003614-63rzzos3	298	5	Inc.	Inc.	NNP
cord-003614-63rzzos3	298	6	,	,	,
cord-003614-63rzzos3	298	7	Cambridge	Cambridge	NNP
cord-003614-63rzzos3	298	8	,	,	,
cord-003614-63rzzos3	298	9	MA	MA	NNP
cord-003614-63rzzos3	298	10	,	,	,
cord-003614-63rzzos3	298	11	USA	USA	NNP
cord-003614-63rzzos3	298	12	,	,	,
cord-003614-63rzzos3	298	13	1:2000	1:2000	CD
cord-003614-63rzzos3	298	14	)	)	-RRB-
cord-003614-63rzzos3	298	15	,	,	,
cord-003614-63rzzos3	298	16	anti	anti	JJ
cord-003614-63rzzos3	298	17	-	-	NNP
cord-003614-63rzzos3	298	18	IRF7	IRF7	NNP
cord-003614-63rzzos3	298	19	(	(	-LRB-
cord-003614-63rzzos3	298	20	ab109255	ab109255	NNP
cord-003614-63rzzos3	298	21	,	,	,
cord-003614-63rzzos3	298	22	Abcam	Abcam	NNP
cord-003614-63rzzos3	298	23	,	,	,
cord-003614-63rzzos3	298	24	1:8000	1:8000	CD
cord-003614-63rzzos3	298	25	)	)	-RRB-
cord-003614-63rzzos3	298	26	and	and	CC
cord-003614-63rzzos3	298	27	anti	anti	JJ
cord-003614-63rzzos3	298	28	-	-	JJ
cord-003614-63rzzos3	298	29	phosphorylated	phosphorylated	JJ
cord-003614-63rzzos3	298	30	PKR	PKR	NNP
cord-003614-63rzzos3	298	31	(	(	-LRB-
cord-003614-63rzzos3	298	32	phospho	phospho	NNP
cord-003614-63rzzos3	298	33	T446	T446	NNPS
cord-003614-63rzzos3	298	34	,	,	,
cord-003614-63rzzos3	298	35	ab32036	ab32036	NNP
cord-003614-63rzzos3	298	36	,	,	,
cord-003614-63rzzos3	298	37	Abcam	Abcam	NNP
cord-003614-63rzzos3	298	38	,	,	,
cord-003614-63rzzos3	298	39	1:600	1:600	CD
cord-003614-63rzzos3	298	40	)	)	-RRB-
cord-003614-63rzzos3	298	41	as	as	RB
cord-003614-63rzzos3	298	42	well	well	RB
cord-003614-63rzzos3	298	43	as	as	IN
cord-003614-63rzzos3	298	44	mouse	mouse	NN
cord-003614-63rzzos3	298	45	monoclonal	monoclonal	JJ
cord-003614-63rzzos3	298	46	anti	anti	JJ
cord-003614-63rzzos3	298	47	-	-	JJ
cord-003614-63rzzos3	298	48	CDV	cdv	JJ
cord-003614-63rzzos3	298	49	(	(	-LRB-
cord-003614-63rzzos3	298	50	D110	d110	XX
cord-003614-63rzzos3	298	51	;	;	:
cord-003614-63rzzos3	298	52	kindly	kindly	RB
cord-003614-63rzzos3	298	53	provided	provide	VBN
cord-003614-63rzzos3	298	54	by	by	IN
cord-003614-63rzzos3	298	55	Prof.	Prof.	NNP
cord-003614-63rzzos3	298	56	Dr.	Dr.	NNP
cord-003614-63rzzos3	298	57	A.	A.	NNP
cord-003614-63rzzos3	298	58	Zurbriggen	Zurbriggen	NNP
cord-003614-63rzzos3	298	59	,	,	,
cord-003614-63rzzos3	298	60	University	University	NNP
cord-003614-63rzzos3	298	61	of	of	IN
cord-003614-63rzzos3	298	62	Bern	Bern	NNP
cord-003614-63rzzos3	298	63	,	,	,
cord-003614-63rzzos3	298	64	Bern	Bern	NNP
cord-003614-63rzzos3	298	65	,	,	,
cord-003614-63rzzos3	298	66	Switzerland	Switzerland	NNP
cord-003614-63rzzos3	298	67	,	,	,
cord-003614-63rzzos3	298	68	1:100	1:100	CD
cord-003614-63rzzos3	298	69	)	)	-RRB-
cord-003614-63rzzos3	298	70	,	,	,
cord-003614-63rzzos3	299	1	anti	anti	NNS
cord-003614-63rzzos3	299	2	-	-	NNS
cord-003614-63rzzos3	299	3	STAT2	STAT2	NNS
cord-003614-63rzzos3	299	4	(	(	-LRB-
cord-003614-63rzzos3	299	5	sc-1668	sc-1668	NNP
cord-003614-63rzzos3	299	6	,	,	,
cord-003614-63rzzos3	299	7	Santa	Santa	NNP
cord-003614-63rzzos3	299	8	Cruz	Cruz	NNP
cord-003614-63rzzos3	299	9	,	,	,
cord-003614-63rzzos3	299	10	1:100	1:100	CD
cord-003614-63rzzos3	299	11	)	)	-RRB-
cord-003614-63rzzos3	299	12	and	and	CC
cord-003614-63rzzos3	299	13	anti	anti	NNP
cord-003614-63rzzos3	299	14	-	-	JJ
cord-003614-63rzzos3	299	15	MX	MX	NNP
cord-003614-63rzzos3	299	16	(	(	-LRB-
cord-003614-63rzzos3	299	17	M143	M143	NNP
cord-003614-63rzzos3	299	18	,	,	,
cord-003614-63rzzos3	299	19	kindly	kindly	RB
cord-003614-63rzzos3	299	20	provided	provide	VBN
cord-003614-63rzzos3	299	21	by	by	IN
cord-003614-63rzzos3	299	22	Prof.	Prof.	NNP
cord-003614-63rzzos3	299	23	Dr.	Dr.	NNP
cord-003614-63rzzos3	299	24	Haller	Haller	NNP
cord-003614-63rzzos3	299	25	and	and	CC
cord-003614-63rzzos3	299	26	PD	PD	NNP
cord-003614-63rzzos3	299	27	.	.	.
cord-003614-63rzzos3	300	1	Dr.	Dr.	NNP
cord-003614-63rzzos3	300	2	Kochs	Kochs	NNP
cord-003614-63rzzos3	300	3	,	,	,
cord-003614-63rzzos3	300	4	University	University	NNP
cord-003614-63rzzos3	300	5	Medical	Medical	NNP
cord-003614-63rzzos3	300	6	Center	Center	NNP
cord-003614-63rzzos3	300	7	Freiburg	Freiburg	NNP
cord-003614-63rzzos3	300	8	,	,	,
cord-003614-63rzzos3	300	9	Freiburg	Freiburg	NNP
cord-003614-63rzzos3	300	10	,	,	,
cord-003614-63rzzos3	300	11	Germany	Germany	NNP
cord-003614-63rzzos3	300	12	,	,	,
cord-003614-63rzzos3	300	13	1:1000	1:1000	NN
cord-003614-63rzzos3	300	14	)	)	-RRB-
cord-003614-63rzzos3	300	15	antibodies	antibody	NNS
cord-003614-63rzzos3	300	16	overnight	overnight	RB
cord-003614-63rzzos3	300	17	at	at	IN
cord-003614-63rzzos3	300	18	4	4	CD
cord-003614-63rzzos3	300	19	•	•	NNP
cord-003614-63rzzos3	300	20	C.	C.	NNP
cord-003614-63rzzos3	300	21	Sections	Sections	NNP
cord-003614-63rzzos3	300	22	incubated	incubate	VBN
cord-003614-63rzzos3	300	23	with	with	IN
cord-003614-63rzzos3	300	24	normal	normal	JJ
cord-003614-63rzzos3	300	25	rabbit	rabbit	NN
cord-003614-63rzzos3	300	26	serum	serum	NN
cord-003614-63rzzos3	300	27	(	(	-LRB-
cord-003614-63rzzos3	300	28	R4505	R4505	NNP
cord-003614-63rzzos3	300	29	,	,	,
cord-003614-63rzzos3	300	30	Sigma	Sigma	NNP
cord-003614-63rzzos3	300	31	-	-	HYPH
cord-003614-63rzzos3	300	32	Aldrich	Aldrich	NNP
cord-003614-63rzzos3	300	33	Chemie	Chemie	NNP
cord-003614-63rzzos3	300	34	GmbH	GmbH	NNP
cord-003614-63rzzos3	300	35	,	,	,
cord-003614-63rzzos3	300	36	Munich	Munich	NNP
cord-003614-63rzzos3	300	37	,	,	,
cord-003614-63rzzos3	300	38	Germany	Germany	NNP
cord-003614-63rzzos3	300	39	)	)	-RRB-
cord-003614-63rzzos3	300	40	or	or	CC
cord-003614-63rzzos3	300	41	IgG	igg	NN
cord-003614-63rzzos3	300	42	-	-	HYPH
cord-003614-63rzzos3	300	43	containing	contain	VBG
cord-003614-63rzzos3	300	44	ascites	ascite	NNS
cord-003614-63rzzos3	300	45	of	of	IN
cord-003614-63rzzos3	300	46	Balb	Balb	NNP
cord-003614-63rzzos3	300	47	/	/	SYM
cord-003614-63rzzos3	300	48	C	C	NNP
cord-003614-63rzzos3	300	49	mice	mouse	NNS
cord-003614-63rzzos3	300	50	instead	instead	RB
cord-003614-63rzzos3	300	51	of	of	IN
cord-003614-63rzzos3	300	52	primary	primary	JJ
cord-003614-63rzzos3	300	53	antibodies	antibody	NNS
cord-003614-63rzzos3	300	54	served	serve	VBN
cord-003614-63rzzos3	300	55	as	as	IN
cord-003614-63rzzos3	300	56	negative	negative	JJ
cord-003614-63rzzos3	300	57	controls	control	NNS
cord-003614-63rzzos3	300	58	.	.	.
cord-003614-63rzzos3	301	1	Biotinylated	Biotinylated	NNP
cord-003614-63rzzos3	301	2	goat	goat	NN
cord-003614-63rzzos3	301	3	-	-	HYPH
cord-003614-63rzzos3	301	4	anti	anti	JJ
cord-003614-63rzzos3	301	5	-	-	JJ
cord-003614-63rzzos3	301	6	rabbit	rabbit	JJ
cord-003614-63rzzos3	301	7	IgG	igg	NN
cord-003614-63rzzos3	301	8	(	(	-LRB-
cord-003614-63rzzos3	301	9	BA-1000	BA-1000	NNP
cord-003614-63rzzos3	301	10	)	)	-RRB-
cord-003614-63rzzos3	301	11	or	or	CC
cord-003614-63rzzos3	301	12	goat	goat	NN
cord-003614-63rzzos3	301	13	-	-	HYPH
cord-003614-63rzzos3	301	14	anti	anti	JJ
cord-003614-63rzzos3	301	15	-	-	JJ
cord-003614-63rzzos3	301	16	mouse	mouse	JJ
cord-003614-63rzzos3	301	17	IgG	igg	NN
cord-003614-63rzzos3	301	18	(	(	-LRB-
cord-003614-63rzzos3	301	19	BA-9200	BA-9200	NNP
cord-003614-63rzzos3	301	20	)	)	-RRB-
cord-003614-63rzzos3	301	21	,	,	,
cord-003614-63rzzos3	301	22	diluted	dilute	VBN
cord-003614-63rzzos3	301	23	1:200	1:200	CD
cord-003614-63rzzos3	301	24	(	(	-LRB-
cord-003614-63rzzos3	301	25	Vector	Vector	NNP
cord-003614-63rzzos3	301	26	Laboratories	Laboratories	NNPS
cord-003614-63rzzos3	301	27	Inc.	Inc.	NNP
cord-003614-63rzzos3	301	28	,	,	,
cord-003614-63rzzos3	301	29	Burlingame	Burlingame	NNP
cord-003614-63rzzos3	301	30	,	,	,
cord-003614-63rzzos3	301	31	CA	CA	NNP
cord-003614-63rzzos3	301	32	,	,	,
cord-003614-63rzzos3	301	33	USA	USA	NNP
cord-003614-63rzzos3	301	34	)	)	-RRB-
cord-003614-63rzzos3	301	35	,	,	,
cord-003614-63rzzos3	301	36	were	be	VBD
cord-003614-63rzzos3	301	37	used	use	VBN
cord-003614-63rzzos3	301	38	as	as	IN
cord-003614-63rzzos3	301	39	secondary	secondary	JJ
cord-003614-63rzzos3	301	40	antibodies	antibody	NNS
cord-003614-63rzzos3	301	41	.	.	.
cord-003614-63rzzos3	302	1	Immunolabeling	Immunolabeling	NNP
cord-003614-63rzzos3	302	2	was	be	VBD
cord-003614-63rzzos3	302	3	visualized	visualize	VBN
cord-003614-63rzzos3	302	4	by	by	IN
cord-003614-63rzzos3	302	5	using	use	VBG
cord-003614-63rzzos3	302	6	the	the	DT
cord-003614-63rzzos3	302	7	avidin	avidin	NN
cord-003614-63rzzos3	302	8	-	-	HYPH
cord-003614-63rzzos3	302	9	biotin	biotin	NN
cord-003614-63rzzos3	302	10	-	-	HYPH
cord-003614-63rzzos3	302	11	peroxidase	peroxidase	NN
cord-003614-63rzzos3	302	12	complex	complex	JJ
cord-003614-63rzzos3	302	13	method	method	NN
cord-003614-63rzzos3	302	14	(	(	-LRB-
cord-003614-63rzzos3	302	15	PK6100	pk6100	NN
cord-003614-63rzzos3	302	16	,	,	,
cord-003614-63rzzos3	302	17	Vector	Vector	NNP
cord-003614-63rzzos3	302	18	Laboratories	Laboratories	NNPS
cord-003614-63rzzos3	302	19	)	)	-RRB-
cord-003614-63rzzos3	302	20	and	and	CC
cord-003614-63rzzos3	302	21	the	the	DT
cord-003614-63rzzos3	302	22	chromogen	chromogen	NNP
cord-003614-63rzzos3	302	23	3,3	3,3	CD
cord-003614-63rzzos3	302	24	-diaminobenzidine	-diaminobenzidine	JJ
cord-003614-63rzzos3	302	25	-	-	HYPH
cord-003614-63rzzos3	302	26	tetrahydrochloride	tetrahydrochloride	NN
cord-003614-63rzzos3	302	27	with	with	IN
cord-003614-63rzzos3	302	28	0.05	0.05	CD
cord-003614-63rzzos3	302	29	%	%	NN
cord-003614-63rzzos3	302	30	hydrogen	hydrogen	NN
cord-003614-63rzzos3	302	31	peroxide	peroxide	NN
cord-003614-63rzzos3	302	32	.	.	.
cord-003614-63rzzos3	303	1	Finally	finally	RB
cord-003614-63rzzos3	303	2	,	,	,
cord-003614-63rzzos3	303	3	sections	section	NNS
cord-003614-63rzzos3	303	4	were	be	VBD
cord-003614-63rzzos3	303	5	slightly	slightly	RB
cord-003614-63rzzos3	303	6	counterstained	counterstaine	VBN
cord-003614-63rzzos3	303	7	with	with	IN
cord-003614-63rzzos3	303	8	Mayer	Mayer	NNP
cord-003614-63rzzos3	303	9	's	's	POS
cord-003614-63rzzos3	303	10	hematoxylin	hematoxylin	NN
cord-003614-63rzzos3	303	11	.	.	.
cord-003614-63rzzos3	304	1	Every	every	DT
cord-003614-63rzzos3	304	2	immunohistochemically	immunohistochemically	RB
cord-003614-63rzzos3	304	3	stained	stain	VBN
cord-003614-63rzzos3	304	4	slide	slide	NN
cord-003614-63rzzos3	304	5	was	be	VBD
cord-003614-63rzzos3	304	6	photographed	photograph	VBN
cord-003614-63rzzos3	304	7	with	with	IN
cord-003614-63rzzos3	304	8	a	a	DT
cord-003614-63rzzos3	304	9	digital	digital	JJ
cord-003614-63rzzos3	304	10	microscope	microscope	NN
cord-003614-63rzzos3	304	11	(	(	-LRB-
cord-003614-63rzzos3	304	12	HS	HS	NNP
cord-003614-63rzzos3	304	13	All	all	RB
cord-003614-63rzzos3	304	14	-	-	HYPH
cord-003614-63rzzos3	304	15	in	in	IN
cord-003614-63rzzos3	304	16	-	-	HYPH
cord-003614-63rzzos3	304	17	one	one	CD
cord-003614-63rzzos3	304	18	Fluorescence	fluorescence	NN
cord-003614-63rzzos3	304	19	Microscope	microscope	NN
cord-003614-63rzzos3	304	20	BZ-9000	BZ-9000	NNP
cord-003614-63rzzos3	304	21	Generation	Generation	NNP
cord-003614-63rzzos3	304	22	II	II	NNP
cord-003614-63rzzos3	304	23	,	,	,
cord-003614-63rzzos3	304	24	BIOREVO	BIOREVO	NNP
cord-003614-63rzzos3	304	25	,	,	,
cord-003614-63rzzos3	304	26	KEYENCE	KEYENCE	NNP
cord-003614-63rzzos3	304	27	Deutschland	Deutschland	NNP
cord-003614-63rzzos3	304	28	GmbH	GmbH	NNP
cord-003614-63rzzos3	304	29	,	,	,
cord-003614-63rzzos3	304	30	Neu	Neu	NNP
cord-003614-63rzzos3	304	31	-	-	HYPH
cord-003614-63rzzos3	304	32	Isenburg	Isenburg	NNP
cord-003614-63rzzos3	304	33	,	,	,
cord-003614-63rzzos3	304	34	Germany	Germany	NNP
cord-003614-63rzzos3	304	35	)	)	-RRB-
cord-003614-63rzzos3	304	36	and	and	CC
cord-003614-63rzzos3	304	37	afterwards	afterwards	RB
cord-003614-63rzzos3	304	38	analyzed	analyze	VBD
cord-003614-63rzzos3	304	39	using	use	VBG
cord-003614-63rzzos3	304	40	analysis	analysis	NN
cord-003614-63rzzos3	304	41	software	software	NN
cord-003614-63rzzos3	304	42	(	(	-LRB-
cord-003614-63rzzos3	304	43	analySIS	analySIS	NNP
cord-003614-63rzzos3	304	44	3.1	3.1	CD
cord-003614-63rzzos3	304	45	software	software	NN
cord-003614-63rzzos3	304	46	package	package	NN
cord-003614-63rzzos3	304	47	,	,	,
cord-003614-63rzzos3	304	48	Soft	Soft	NNP
cord-003614-63rzzos3	304	49	Imaging	Imaging	NNP
cord-003614-63rzzos3	304	50	System	System	NNP
cord-003614-63rzzos3	304	51	GmbH	GmbH	NNP
cord-003614-63rzzos3	304	52	,	,	,
cord-003614-63rzzos3	304	53	Münster	Münster	NNP
cord-003614-63rzzos3	304	54	,	,	,
cord-003614-63rzzos3	304	55	Germany	Germany	NNP
cord-003614-63rzzos3	304	56	)	)	-RRB-
cord-003614-63rzzos3	304	57	.	.	.
cord-003614-63rzzos3	305	1	Percentage	percentage	NN
cord-003614-63rzzos3	305	2	of	of	IN
cord-003614-63rzzos3	305	3	immunopositive	immunopositive	JJ
cord-003614-63rzzos3	305	4	areas	area	NNS
cord-003614-63rzzos3	305	5	are	be	VBP
cord-003614-63rzzos3	305	6	shown	show	VBN
cord-003614-63rzzos3	305	7	as	as	IN
cord-003614-63rzzos3	305	8	Box	Box	NNP
cord-003614-63rzzos3	305	9	-	-	HYPH
cord-003614-63rzzos3	305	10	and	and	CC
cord-003614-63rzzos3	305	11	-	-	HYPH
cord-003614-63rzzos3	305	12	Whisker	whisker	NN
cord-003614-63rzzos3	305	13	plots	plot	NNS
cord-003614-63rzzos3	305	14	with	with	IN
cord-003614-63rzzos3	305	15	median	median	NN
cord-003614-63rzzos3	305	16	,	,	,
cord-003614-63rzzos3	305	17	minimum	minimum	NN
cord-003614-63rzzos3	305	18	and	and	CC
cord-003614-63rzzos3	305	19	maximum	maximum	NN
cord-003614-63rzzos3	305	20	in	in	IN
cord-003614-63rzzos3	305	21	a	a	DT
cord-003614-63rzzos3	305	22	logarithmic	logarithmic	JJ
cord-003614-63rzzos3	305	23	scale	scale	NN
cord-003614-63rzzos3	305	24	.	.	.
cord-003614-63rzzos3	306	1	To	to	TO
cord-003614-63rzzos3	306	2	determine	determine	VB
cord-003614-63rzzos3	306	3	the	the	DT
cord-003614-63rzzos3	306	4	cellular	cellular	JJ
cord-003614-63rzzos3	306	5	origin	origin	NN
cord-003614-63rzzos3	306	6	of	of	IN
cord-003614-63rzzos3	306	7	selected	select	VBN
cord-003614-63rzzos3	306	8	members	member	NNS
cord-003614-63rzzos3	306	9	of	of	IN
cord-003614-63rzzos3	306	10	the	the	DT
cord-003614-63rzzos3	306	11	JAK	JAK	NNP
cord-003614-63rzzos3	306	12	-	-	HYPH
cord-003614-63rzzos3	306	13	STAT	STAT	NNP
cord-003614-63rzzos3	306	14	signaling	signal	VBG
cord-003614-63rzzos3	306	15	pathway	pathway	NN
cord-003614-63rzzos3	306	16	(	(	-LRB-
cord-003614-63rzzos3	306	17	STAT1	stat1	XX
cord-003614-63rzzos3	306	18	,	,	,
cord-003614-63rzzos3	306	19	STAT2	STAT2	NNS
cord-003614-63rzzos3	306	20	)	)	-RRB-
cord-003614-63rzzos3	306	21	and	and	CC
cord-003614-63rzzos3	306	22	downstream	downstream	JJ
cord-003614-63rzzos3	306	23	ISGs	ISGs	NNPS
cord-003614-63rzzos3	306	24	(	(	-LRB-
cord-003614-63rzzos3	306	25	MX	MX	NNP
cord-003614-63rzzos3	306	26	and	and	CC
cord-003614-63rzzos3	306	27	PKR	PKR	NNP
cord-003614-63rzzos3	306	28	)	)	-RRB-
cord-003614-63rzzos3	306	29	,	,	,
cord-003614-63rzzos3	306	30	immunofluorescence	immunofluorescence	NN
cord-003614-63rzzos3	306	31	double	double	JJ
cord-003614-63rzzos3	306	32	-	-	HYPH
cord-003614-63rzzos3	306	33	labeling	labeling	NN
cord-003614-63rzzos3	306	34	was	be	VBD
cord-003614-63rzzos3	306	35	performed	perform	VBN
cord-003614-63rzzos3	306	36	using	use	VBG
cord-003614-63rzzos3	306	37	markers	marker	NNS
cord-003614-63rzzos3	306	38	for	for	IN
cord-003614-63rzzos3	306	39	oligodendrocytes	oligodendrocyte	NNS
cord-003614-63rzzos3	306	40	(	(	-LRB-
cord-003614-63rzzos3	306	41	NogoA	NogoA	NNP
cord-003614-63rzzos3	306	42	)	)	-RRB-
cord-003614-63rzzos3	306	43	,	,	,
cord-003614-63rzzos3	306	44	astrocytes	astrocyte	NNS
cord-003614-63rzzos3	306	45	(	(	-LRB-
cord-003614-63rzzos3	306	46	GFAP	GFAP	NNP
cord-003614-63rzzos3	306	47	)	)	-RRB-
cord-003614-63rzzos3	306	48	and	and	CC
cord-003614-63rzzos3	306	49	microglia	microglia	NNS
cord-003614-63rzzos3	306	50	/	/	SYM
cord-003614-63rzzos3	306	51	macrophages	macrophage	NNS
cord-003614-63rzzos3	306	52	(	(	-LRB-
cord-003614-63rzzos3	306	53	IBA1	IBA1	NNP
cord-003614-63rzzos3	306	54	)	)	-RRB-
cord-003614-63rzzos3	306	55	.	.	.
cord-003614-63rzzos3	307	1	Moreover	moreover	RB
cord-003614-63rzzos3	307	2	,	,	,
cord-003614-63rzzos3	307	3	double	double	JJ
cord-003614-63rzzos3	307	4	-	-	HYPH
cord-003614-63rzzos3	307	5	staining	staining	NN
cord-003614-63rzzos3	307	6	was	be	VBD
cord-003614-63rzzos3	307	7	used	use	VBN
cord-003614-63rzzos3	307	8	to	to	TO
cord-003614-63rzzos3	307	9	investigate	investigate	VB
cord-003614-63rzzos3	307	10	the	the	DT
cord-003614-63rzzos3	307	11	infection	infection	NN
cord-003614-63rzzos3	307	12	status	status	NN
cord-003614-63rzzos3	307	13	of	of	IN
cord-003614-63rzzos3	307	14	cells	cell	NNS
cord-003614-63rzzos3	307	15	expressing	express	VBG
cord-003614-63rzzos3	307	16	STAT1	stat1	NN
cord-003614-63rzzos3	307	17	,	,	,
cord-003614-63rzzos3	307	18	STAT2	STAT2	NNS
cord-003614-63rzzos3	307	19	and	and	CC
cord-003614-63rzzos3	307	20	MX	MX	NNP
cord-003614-63rzzos3	307	21	.	.	.
cord-003614-63rzzos3	308	1	Immunofluorescence	Immunofluorescence	NNP
cord-003614-63rzzos3	308	2	was	be	VBD
cord-003614-63rzzos3	308	3	performed	perform	VBN
cord-003614-63rzzos3	308	4	on	on	IN
cord-003614-63rzzos3	308	5	selected	select	VBN
cord-003614-63rzzos3	308	6	sections	section	NNS
cord-003614-63rzzos3	308	7	of	of	IN
cord-003614-63rzzos3	308	8	subacute	subacute	JJ
cord-003614-63rzzos3	308	9	and	and	CC
cord-003614-63rzzos3	308	10	chronic	chronic	JJ
cord-003614-63rzzos3	308	11	lesions	lesion	NNS
cord-003614-63rzzos3	308	12	due	due	JJ
cord-003614-63rzzos3	308	13	to	to	IN
cord-003614-63rzzos3	308	14	the	the	DT
cord-003614-63rzzos3	308	15	strong	strong	JJ
cord-003614-63rzzos3	308	16	expression	expression	NN
cord-003614-63rzzos3	308	17	of	of	IN
cord-003614-63rzzos3	308	18	the	the	DT
cord-003614-63rzzos3	308	19	investigated	investigate	VBN
cord-003614-63rzzos3	308	20	markers	marker	NNS
cord-003614-63rzzos3	308	21	in	in	IN
cord-003614-63rzzos3	308	22	the	the	DT
cord-003614-63rzzos3	308	23	microarray	microarray	NN
cord-003614-63rzzos3	308	24	analysis	analysis	NN
cord-003614-63rzzos3	308	25	and	and	CC
cord-003614-63rzzos3	308	26	immunohistochemical	immunohistochemical	JJ
cord-003614-63rzzos3	308	27	evaluation	evaluation	NN
cord-003614-63rzzos3	308	28	.	.	.
cord-003614-63rzzos3	309	1	Dewaxing	Dewaxing	NNP
cord-003614-63rzzos3	309	2	,	,	,
cord-003614-63rzzos3	309	3	rehydration	rehydration	NN
cord-003614-63rzzos3	309	4	,	,	,
cord-003614-63rzzos3	309	5	pretreatment	pretreatment	NN
cord-003614-63rzzos3	309	6	and	and	CC
cord-003614-63rzzos3	309	7	blocking	blocking	NN
cord-003614-63rzzos3	309	8	of	of	IN
cord-003614-63rzzos3	309	9	non	non	JJ
cord-003614-63rzzos3	309	10	-	-	JJ
cord-003614-63rzzos3	309	11	specific	specific	JJ
cord-003614-63rzzos3	309	12	binding	binding	NN
cord-003614-63rzzos3	309	13	with	with	IN
cord-003614-63rzzos3	309	14	20	20	CD
cord-003614-63rzzos3	309	15	%	%	NN
cord-003614-63rzzos3	309	16	goat	goat	NN
cord-003614-63rzzos3	309	17	serum	serum	NN
cord-003614-63rzzos3	309	18	or	or	CC
cord-003614-63rzzos3	309	19	20	20	CD
cord-003614-63rzzos3	309	20	%	%	NN
cord-003614-63rzzos3	309	21	horse	horse	NN
cord-003614-63rzzos3	309	22	serum	serum	NN
cord-003614-63rzzos3	309	23	was	be	VBD
cord-003614-63rzzos3	309	24	performed	perform	VBN
cord-003614-63rzzos3	309	25	as	as	IN
cord-003614-63rzzos3	309	26	described	describe	VBN
cord-003614-63rzzos3	309	27	for	for	IN
cord-003614-63rzzos3	309	28	immunohistochemistry	immunohistochemistry	NN
cord-003614-63rzzos3	309	29	without	without	IN
cord-003614-63rzzos3	309	30	blocking	block	VBG
cord-003614-63rzzos3	309	31	the	the	DT
cord-003614-63rzzos3	309	32	endogenous	endogenous	JJ
cord-003614-63rzzos3	309	33	peroxidase	peroxidase	NN
cord-003614-63rzzos3	309	34	.	.	.
cord-003614-63rzzos3	310	1	Sections	section	NNS
cord-003614-63rzzos3	310	2	were	be	VBD
cord-003614-63rzzos3	310	3	co	co	VBN
cord-003614-63rzzos3	310	4	-	-	VBN
cord-003614-63rzzos3	310	5	incubated	incubate	VBN
cord-003614-63rzzos3	310	6	with	with	IN
cord-003614-63rzzos3	310	7	antibodies	antibody	NNS
cord-003614-63rzzos3	310	8	directed	direct	VBN
cord-003614-63rzzos3	310	9	against	against	IN
cord-003614-63rzzos3	310	10	phosphorylated	phosphorylated	JJ
cord-003614-63rzzos3	310	11	STAT1	stat1	NN
cord-003614-63rzzos3	310	12	(	(	-LRB-
cord-003614-63rzzos3	310	13	sc-346	sc-346	NN
cord-003614-63rzzos3	310	14	;	;	:
cord-003614-63rzzos3	310	15	1:100	1:100	CD
cord-003614-63rzzos3	310	16	)	)	-RRB-
cord-003614-63rzzos3	310	17	,	,	.
cord-003614-63rzzos3	311	1	STAT2	STAT2	NNS
cord-003614-63rzzos3	312	1	(	(	-LRB-
cord-003614-63rzzos3	313	1	sc-1668	sc-1668	LS
cord-003614-63rzzos3	313	2	;	;	:
cord-003614-63rzzos3	313	3	1:50	1:50	CD
cord-003614-63rzzos3	313	4	)	)	-RRB-
cord-003614-63rzzos3	313	5	,	,	,
cord-003614-63rzzos3	313	6	MX	MX	NNP
cord-003614-63rzzos3	313	7	(	(	-LRB-
cord-003614-63rzzos3	313	8	M143	M143	NNP
cord-003614-63rzzos3	313	9	;	;	:
cord-003614-63rzzos3	313	10	1:100	1:100	CD
cord-003614-63rzzos3	313	11	)	)	-RRB-
cord-003614-63rzzos3	313	12	or	or	CC
cord-003614-63rzzos3	313	13	phosphorylated	phosphorylate	VBN
cord-003614-63rzzos3	313	14	PKR	PKR	NNP
cord-003614-63rzzos3	313	15	(	(	-LRB-
cord-003614-63rzzos3	313	16	ab32036	ab32036	JJ
cord-003614-63rzzos3	313	17	;	;	:
cord-003614-63rzzos3	313	18	1:50	1:50	CD
cord-003614-63rzzos3	313	19	)	)	-RRB-
cord-003614-63rzzos3	313	20	and	and	CC
cord-003614-63rzzos3	313	21	antibodies	antibody	NNS
cord-003614-63rzzos3	313	22	directed	direct	VBN
cord-003614-63rzzos3	313	23	against	against	IN
cord-003614-63rzzos3	313	24	GFAP	GFAP	NNP
cord-003614-63rzzos3	313	25	(	(	-LRB-
cord-003614-63rzzos3	313	26	goat	goat	NN
cord-003614-63rzzos3	313	27	polyclonal	polyclonal	JJ
cord-003614-63rzzos3	313	28	,	,	,
cord-003614-63rzzos3	313	29	ab53554	ab53554	NNP
cord-003614-63rzzos3	313	30	,	,	,
cord-003614-63rzzos3	313	31	Abcam	Abcam	NNP
cord-003614-63rzzos3	313	32	,	,	,
cord-003614-63rzzos3	313	33	1:200	1:200	CD
cord-003614-63rzzos3	313	34	or	or	CC
cord-003614-63rzzos3	313	35	rabbit	rabbit	NN
cord-003614-63rzzos3	313	36	polyclonal	polyclonal	NN
cord-003614-63rzzos3	313	37	,	,	,
cord-003614-63rzzos3	313	38	Dakocytomation	Dakocytomation	NNP
cord-003614-63rzzos3	313	39	GmbH	GmbH	NNP
cord-003614-63rzzos3	313	40	,	,	,
cord-003614-63rzzos3	313	41	Hamburg	Hamburg	NNP
cord-003614-63rzzos3	313	42	,	,	,
cord-003614-63rzzos3	313	43	Germany	Germany	NNP
cord-003614-63rzzos3	313	44	,	,	,
cord-003614-63rzzos3	313	45	1:1000	1:1000	CD
cord-003614-63rzzos3	313	46	)	)	-RRB-
cord-003614-63rzzos3	313	47	,	,	,
cord-003614-63rzzos3	313	48	NogoA	NogoA	NNP
cord-003614-63rzzos3	313	49	(	(	-LRB-
cord-003614-63rzzos3	313	50	C-4	C-4	NNP
cord-003614-63rzzos3	313	51	,	,	,
cord-003614-63rzzos3	313	52	mouse	mouse	NN
cord-003614-63rzzos3	313	53	monoclonal	monoclonal	JJ
cord-003614-63rzzos3	313	54	,	,	,
cord-003614-63rzzos3	313	55	sc-271878	sc-271878	NNP
cord-003614-63rzzos3	313	56	,	,	,
cord-003614-63rzzos3	313	57	Santa	Santa	NNP
cord-003614-63rzzos3	313	58	Cruz	Cruz	NNP
cord-003614-63rzzos3	313	59	,	,	,
cord-003614-63rzzos3	313	60	1:200	1:200	CD
cord-003614-63rzzos3	313	61	or	or	CC
cord-003614-63rzzos3	313	62	rabbit	rabbit	NN
cord-003614-63rzzos3	313	63	polyclonal	polyclonal	NN
cord-003614-63rzzos3	313	64	,	,	.
cord-003614-63rzzos3	314	1	Millipore	Millipore	NNP
cord-003614-63rzzos3	314	2	/	/	SYM
cord-003614-63rzzos3	314	3	Chemicon	Chemicon	NNP
cord-003614-63rzzos3	314	4	,	,	,
cord-003614-63rzzos3	314	5	Catalog	Catalog	NNP
cord-003614-63rzzos3	314	6	-	-	HYPH
cord-003614-63rzzos3	314	7	No	no	NN
cord-003614-63rzzos3	314	8	.	.	.
cord-003614-63rzzos3	315	1	AB5664P	AB5664P	NNP
cord-003614-63rzzos3	315	2	,	,	,
cord-003614-63rzzos3	315	3	1:500	1:500	CD
cord-003614-63rzzos3	315	4	)	)	-RRB-
cord-003614-63rzzos3	315	5	,	,	,
cord-003614-63rzzos3	315	6	IBA1	IBA1	NNP
cord-003614-63rzzos3	315	7	(	(	-LRB-
cord-003614-63rzzos3	315	8	mouse	mouse	NN
cord-003614-63rzzos3	315	9	monoclonal	monoclonal	JJ
cord-003614-63rzzos3	315	10	,	,	,
cord-003614-63rzzos3	315	11	ab15690	ab15690	NNP
cord-003614-63rzzos3	315	12	,	,	,
cord-003614-63rzzos3	315	13	Abcam	Abcam	NNP
cord-003614-63rzzos3	315	14	,	,	,
cord-003614-63rzzos3	315	15	1:300	1:300	CD
cord-003614-63rzzos3	315	16	or	or	CC
cord-003614-63rzzos3	315	17	rabbit	rabbit	NN
cord-003614-63rzzos3	315	18	polyclonal	polyclonal	NN
cord-003614-63rzzos3	315	19	,	,	,
cord-003614-63rzzos3	315	20	ThermoFisher	ThermoFisher	NNP
cord-003614-63rzzos3	315	21	Scientific	Scientific	NNP
cord-003614-63rzzos3	315	22	,	,	,
cord-003614-63rzzos3	315	23	Schwerte	Schwerte	NNP
cord-003614-63rzzos3	315	24	,	,	,
cord-003614-63rzzos3	315	25	Germany	Germany	NNP
cord-003614-63rzzos3	315	26	,	,	,
cord-003614-63rzzos3	315	27	Catalog	Catalog	NNP
cord-003614-63rzzos3	315	28	-	-	HYPH
cord-003614-63rzzos3	315	29	No	no	NN
cord-003614-63rzzos3	315	30	.	.	.
cord-003614-63rzzos3	316	1	PA5	PA5	NNP
cord-003614-63rzzos3	316	2	-	-	HYPH
cord-003614-63rzzos3	316	3	27436	27436	CD
cord-003614-63rzzos3	316	4	,	,	,
cord-003614-63rzzos3	316	5	1:500	1:500	CD
cord-003614-63rzzos3	316	6	)	)	-RRB-
cord-003614-63rzzos3	316	7	or	or	CC
cord-003614-63rzzos3	316	8	CDV	CDV	NNP
cord-003614-63rzzos3	316	9	(	(	-LRB-
cord-003614-63rzzos3	316	10	D110	d110	XX
cord-003614-63rzzos3	316	11	,	,	,
cord-003614-63rzzos3	316	12	mouse	mouse	NN
cord-003614-63rzzos3	316	13	monoclonal	monoclonal	JJ
cord-003614-63rzzos3	316	14	,	,	,
cord-003614-63rzzos3	316	15	1:100	1:100	CD
cord-003614-63rzzos3	316	16	or	or	CC
cord-003614-63rzzos3	316	17	#	#	$
cord-003614-63rzzos3	316	18	25	25	CD
cord-003614-63rzzos3	316	19	,	,	,
cord-003614-63rzzos3	316	20	kindly	kindly	RB
cord-003614-63rzzos3	316	21	provided	provide	VBN
cord-003614-63rzzos3	316	22	by	by	IN
cord-003614-63rzzos3	316	23	C.	C.	NNP
cord-003614-63rzzos3	316	24	Örvell	Örvell	NNP
cord-003614-63rzzos3	316	25	,	,	,
cord-003614-63rzzos3	316	26	Karolinska	Karolinska	NNP
cord-003614-63rzzos3	316	27	University	University	NNP
cord-003614-63rzzos3	316	28	Hospital	Hospital	NNP
cord-003614-63rzzos3	316	29	,	,	,
cord-003614-63rzzos3	316	30	Stockholm	Stockholm	NNP
cord-003614-63rzzos3	316	31	,	,	,
cord-003614-63rzzos3	316	32	Sweden	Sweden	NNP
cord-003614-63rzzos3	316	33	,	,	,
cord-003614-63rzzos3	316	34	rabbit	rabbit	NN
cord-003614-63rzzos3	316	35	polyclonal	polyclonal	NN
cord-003614-63rzzos3	316	36	,	,	,
cord-003614-63rzzos3	316	37	1:2000	1:2000	CD
cord-003614-63rzzos3	316	38	)	)	-RRB-
cord-003614-63rzzos3	317	1	overnight	overnight	RB
cord-003614-63rzzos3	317	2	at	at	IN
cord-003614-63rzzos3	317	3	4	4	CD
cord-003614-63rzzos3	317	4	•	•	NN
cord-003614-63rzzos3	318	1	C.	C.	NNP
cord-003614-63rzzos3	318	2	Negative	negative	JJ
cord-003614-63rzzos3	318	3	controls	control	NNS
cord-003614-63rzzos3	318	4	were	be	VBD
cord-003614-63rzzos3	318	5	included	include	VBN
cord-003614-63rzzos3	318	6	in	in	IN
cord-003614-63rzzos3	318	7	accordance	accordance	NN
cord-003614-63rzzos3	318	8	with	with	IN
cord-003614-63rzzos3	318	9	the	the	DT
cord-003614-63rzzos3	318	10	immunohistochemical	immunohistochemical	JJ
cord-003614-63rzzos3	318	11	investigation	investigation	NN
cord-003614-63rzzos3	318	12	.	.	.
cord-003614-63rzzos3	319	1	Subsequently	subsequently	RB
cord-003614-63rzzos3	319	2	,	,	,
cord-003614-63rzzos3	319	3	sections	section	NNS
cord-003614-63rzzos3	319	4	were	be	VBD
cord-003614-63rzzos3	319	5	incubated	incubate	VBN
cord-003614-63rzzos3	319	6	with	with	IN
cord-003614-63rzzos3	319	7	Cy2-and	cy2-and	NN
cord-003614-63rzzos3	319	8	Cy3-conjugated	cy3-conjugated	JJ
cord-003614-63rzzos3	319	9	secondary	secondary	JJ
cord-003614-63rzzos3	319	10	antibodies	antibody	NNS
cord-003614-63rzzos3	319	11	(	(	-LRB-
cord-003614-63rzzos3	319	12	goat	goat	NNP
cord-003614-63rzzos3	319	13	anti	anti	JJ
cord-003614-63rzzos3	319	14	-	-	JJ
cord-003614-63rzzos3	319	15	rabbit	rabbit	JJ
cord-003614-63rzzos3	319	16	,	,	,
cord-003614-63rzzos3	319	17	111	111	CD
cord-003614-63rzzos3	319	18	-	-	SYM
cord-003614-63rzzos3	319	19	165	165	CD
cord-003614-63rzzos3	319	20	-	-	SYM
cord-003614-63rzzos3	319	21	144	144	CD
cord-003614-63rzzos3	319	22	;	;	:
cord-003614-63rzzos3	319	23	goat	goat	NN
cord-003614-63rzzos3	319	24	anti	anti	JJ
cord-003614-63rzzos3	319	25	-	-	JJ
cord-003614-63rzzos3	319	26	mouse	mouse	NN
cord-003614-63rzzos3	319	27	,	,	,
cord-003614-63rzzos3	319	28	115	115	CD
cord-003614-63rzzos3	319	29	-	-	HYPH
cord-003614-63rzzos3	319	30	545	545	CD
cord-003614-63rzzos3	319	31	-	-	HYPH
cord-003614-63rzzos3	319	32	003	003	CD
cord-003614-63rzzos3	319	33	or	or	CC
cord-003614-63rzzos3	319	34	115	115	CD
cord-003614-63rzzos3	319	35	-	-	SYM
cord-003614-63rzzos3	319	36	165	165	CD
cord-003614-63rzzos3	319	37	-	-	SYM
cord-003614-63rzzos3	319	38	166	166	CD
cord-003614-63rzzos3	319	39	;	;	:
cord-003614-63rzzos3	319	40	donkey	donkey	NN
cord-003614-63rzzos3	319	41	anti	anti	JJ
cord-003614-63rzzos3	319	42	-	-	JJ
cord-003614-63rzzos3	319	43	goat	goat	JJ
cord-003614-63rzzos3	319	44	,	,	,
cord-003614-63rzzos3	319	45	705	705	CD
cord-003614-63rzzos3	319	46	-	-	HYPH
cord-003614-63rzzos3	319	47	165	165	CD
cord-003614-63rzzos3	319	48	-	-	SYM
cord-003614-63rzzos3	319	49	147	147	CD
cord-003614-63rzzos3	319	50	;	;	:
cord-003614-63rzzos3	319	51	Jackson	Jackson	NNP
cord-003614-63rzzos3	319	52	ImmunoResearch	ImmunoResearch	NNP
cord-003614-63rzzos3	319	53	Europe	Europe	NNP
cord-003614-63rzzos3	319	54	Ltd.	Ltd.	NNP
cord-003614-63rzzos3	319	55	,	,	,
cord-003614-63rzzos3	319	56	Cambridge	Cambridge	NNP
cord-003614-63rzzos3	319	57	,	,	,
cord-003614-63rzzos3	319	58	UK	UK	NNP
cord-003614-63rzzos3	319	59	;	;	:
cord-003614-63rzzos3	319	60	goat	goat	NNP
cord-003614-63rzzos3	319	61	anti	anti	JJ
cord-003614-63rzzos3	319	62	-	-	JJ
cord-003614-63rzzos3	319	63	rabbit	rabbit	JJ
cord-003614-63rzzos3	319	64	,	,	,
cord-003614-63rzzos3	319	65	A-11034	a-11034	CD
cord-003614-63rzzos3	319	66	;	;	:
cord-003614-63rzzos3	319	67	Invitrogen	Invitrogen	NNP
cord-003614-63rzzos3	319	68	/	/	SYM
cord-003614-63rzzos3	319	69	Thermo	Thermo	NNP
cord-003614-63rzzos3	319	70	Fisher	Fisher	NNP
cord-003614-63rzzos3	319	71	;	;	:
cord-003614-63rzzos3	319	72	donkey	donkey	JJ
cord-003614-63rzzos3	319	73	anti	anti	JJ
cord-003614-63rzzos3	319	74	-	-	JJ
cord-003614-63rzzos3	319	75	rabbit	rabbit	JJ
cord-003614-63rzzos3	319	76	,	,	,
cord-003614-63rzzos3	319	77	ab150073	ab150073	FW
cord-003614-63rzzos3	319	78	;	;	:
cord-003614-63rzzos3	319	79	Abcam	Abcam	NNP
cord-003614-63rzzos3	319	80	;	;	:
cord-003614-63rzzos3	319	81	1:200	1:200	LS
cord-003614-63rzzos3	319	82	)	)	-RRB-
cord-003614-63rzzos3	319	83	for	for	IN
cord-003614-63rzzos3	319	84	45	45	CD
cord-003614-63rzzos3	319	85	min	min	NN
cord-003614-63rzzos3	319	86	at	at	IN
cord-003614-63rzzos3	319	87	room	room	NN
cord-003614-63rzzos3	319	88	temperature	temperature	NN
cord-003614-63rzzos3	319	89	in	in	IN
cord-003614-63rzzos3	319	90	the	the	DT
cord-003614-63rzzos3	319	91	dark	dark	NN
cord-003614-63rzzos3	319	92	.	.	.
cord-003614-63rzzos3	320	1	Nuclei	nucleus	NNS
cord-003614-63rzzos3	320	2	were	be	VBD
cord-003614-63rzzos3	320	3	visualized	visualize	VBN
cord-003614-63rzzos3	320	4	by	by	IN
cord-003614-63rzzos3	320	5	0.01	0.01	CD
cord-003614-63rzzos3	320	6	%	%	NN
cord-003614-63rzzos3	320	7	bisbenzimide	bisbenzimide	NN
cord-003614-63rzzos3	320	8	(	(	-LRB-
cord-003614-63rzzos3	320	9	H33258	H33258	NNP
cord-003614-63rzzos3	320	10	,	,	,
cord-003614-63rzzos3	320	11	Sigma	Sigma	NNP
cord-003614-63rzzos3	320	12	-	-	HYPH
cord-003614-63rzzos3	320	13	Aldrich	Aldrich	NNP
cord-003614-63rzzos3	320	14	)	)	-RRB-
cord-003614-63rzzos3	320	15	and	and	CC
cord-003614-63rzzos3	320	16	sections	section	NNS
cord-003614-63rzzos3	320	17	were	be	VBD
cord-003614-63rzzos3	320	18	mounted	mount	VBN
cord-003614-63rzzos3	320	19	with	with	IN
cord-003614-63rzzos3	320	20	mounting	mount	VBG
cord-003614-63rzzos3	320	21	medium	medium	NN
cord-003614-63rzzos3	320	22	(	(	-LRB-
cord-003614-63rzzos3	320	23	Shandon	Shandon	NNP
cord-003614-63rzzos3	320	24	Immu	Immu	NNP
cord-003614-63rzzos3	320	25	-	-	HYPH
cord-003614-63rzzos3	320	26	Mount	Mount	NNP
cord-003614-63rzzos3	320	27	,	,	,
cord-003614-63rzzos3	320	28	ThermoFisher	ThermoFisher	NNP
cord-003614-63rzzos3	320	29	Scientific	Scientific	NNP
cord-003614-63rzzos3	320	30	,	,	,
cord-003614-63rzzos3	320	31	Catalog	catalog	NN
cord-003614-63rzzos3	320	32	-	-	HYPH
cord-003614-63rzzos3	320	33	No	no	NN
cord-003614-63rzzos3	320	34	.	.	NN
cord-003614-63rzzos3	320	35	9990402	9990402	CD
cord-003614-63rzzos3	320	36	,	,	,
cord-003614-63rzzos3	320	37	USA	USA	NNP
cord-003614-63rzzos3	320	38	)	)	-RRB-
cord-003614-63rzzos3	320	39	.	.	.
cord-003614-63rzzos3	321	1	Sections	section	NNS
cord-003614-63rzzos3	321	2	were	be	VBD
cord-003614-63rzzos3	321	3	photographed	photograph	VBN
cord-003614-63rzzos3	321	4	with	with	IN
cord-003614-63rzzos3	321	5	a	a	DT
cord-003614-63rzzos3	321	6	digital	digital	JJ
cord-003614-63rzzos3	321	7	microscope	microscope	NN
cord-003614-63rzzos3	321	8	(	(	-LRB-
cord-003614-63rzzos3	321	9	HS	HS	NNP
cord-003614-63rzzos3	321	10	All	all	RB
cord-003614-63rzzos3	321	11	-	-	HYPH
cord-003614-63rzzos3	321	12	in	in	IN
cord-003614-63rzzos3	321	13	-	-	HYPH
cord-003614-63rzzos3	321	14	one	one	CD
cord-003614-63rzzos3	321	15	Fluorescence	fluorescence	NN
cord-003614-63rzzos3	321	16	Microscope	microscope	NN
cord-003614-63rzzos3	321	17	BZ-9000	BZ-9000	NNP
cord-003614-63rzzos3	321	18	Generation	Generation	NNP
cord-003614-63rzzos3	321	19	II	II	NNP
cord-003614-63rzzos3	321	20	,	,	,
cord-003614-63rzzos3	321	21	BIOREVO	BIOREVO	NNP
cord-003614-63rzzos3	321	22	,	,	,
cord-003614-63rzzos3	321	23	KEYENCE	KEYENCE	NNP
cord-003614-63rzzos3	321	24	Deutschland	Deutschland	NNP
cord-003614-63rzzos3	321	25	GmbH	GmbH	NNP
cord-003614-63rzzos3	321	26	,	,	,
cord-003614-63rzzos3	321	27	Neu	Neu	NNP
cord-003614-63rzzos3	321	28	-	-	HYPH
cord-003614-63rzzos3	321	29	Isenburg	Isenburg	NNP
cord-003614-63rzzos3	321	30	,	,	,
cord-003614-63rzzos3	321	31	Germany	Germany	NNP
cord-003614-63rzzos3	321	32	)	)	-RRB-
cord-003614-63rzzos3	321	33	.	.	.
cord-003614-63rzzos3	322	1	Microarray	Microarray	NNP
cord-003614-63rzzos3	322	2	data	datum	NNS
cord-003614-63rzzos3	322	3	were	be	VBD
cord-003614-63rzzos3	322	4	analyzed	analyze	VBN
cord-003614-63rzzos3	322	5	with	with	IN
cord-003614-63rzzos3	322	6	non	non	JJ
cord-003614-63rzzos3	322	7	-	-	JJ
cord-003614-63rzzos3	322	8	parametric	parametric	JJ
cord-003614-63rzzos3	322	9	Mann	Mann	NNP
cord-003614-63rzzos3	322	10	-	-	HYPH
cord-003614-63rzzos3	322	11	Whitney	Whitney	NNP
cord-003614-63rzzos3	322	12	U	U	NNP
cord-003614-63rzzos3	322	13	tests	test	VBZ
cord-003614-63rzzos3	322	14	(	(	-LRB-
cord-003614-63rzzos3	322	15	Prism	Prism	NNP
cord-003614-63rzzos3	322	16	6	6	CD
cord-003614-63rzzos3	322	17	,	,	,
cord-003614-63rzzos3	322	18	GraphPad	GraphPad	NNP
cord-003614-63rzzos3	322	19	Software	Software	NNP
cord-003614-63rzzos3	322	20	Ltd.	Ltd.	NNP
cord-003614-63rzzos3	322	21	,	,	,
cord-003614-63rzzos3	322	22	La	La	NNP
cord-003614-63rzzos3	322	23	Jolla	Jolla	NNP
cord-003614-63rzzos3	322	24	,	,	,
cord-003614-63rzzos3	322	25	CA	CA	NNP
cord-003614-63rzzos3	322	26	,	,	,
cord-003614-63rzzos3	322	27	USA	USA	NNP
cord-003614-63rzzos3	322	28	)	)	-RRB-
cord-003614-63rzzos3	322	29	,	,	,
cord-003614-63rzzos3	322	30	comparing	compare	VBG
cord-003614-63rzzos3	322	31	each	each	DT
cord-003614-63rzzos3	322	32	group	group	NN
cord-003614-63rzzos3	322	33	of	of	IN
cord-003614-63rzzos3	322	34	CDV	CDV	NNP
cord-003614-63rzzos3	322	35	-	-	HYPH
cord-003614-63rzzos3	322	36	infected	infect	VBN
cord-003614-63rzzos3	322	37	dogs	dog	NNS
cord-003614-63rzzos3	322	38	with	with	IN
cord-003614-63rzzos3	322	39	controls	control	NNS
cord-003614-63rzzos3	322	40	.	.	.
cord-003614-63rzzos3	323	1	Immunohistochemically	Immunohistochemically	NNP
cord-003614-63rzzos3	323	2	data	datum	NNS
cord-003614-63rzzos3	323	3	were	be	VBD
cord-003614-63rzzos3	323	4	analyzed	analyze	VBN
cord-003614-63rzzos3	323	5	using	use	VBG
cord-003614-63rzzos3	323	6	Kruskal	Kruskal	NNP
cord-003614-63rzzos3	323	7	-	-	HYPH
cord-003614-63rzzos3	323	8	Wallis	Wallis	NNP
cord-003614-63rzzos3	323	9	tests	test	VBZ
cord-003614-63rzzos3	323	10	and	and	CC
cord-003614-63rzzos3	323	11	Dunn	Dunn	NNP
cord-003614-63rzzos3	323	12	's	's	POS
cord-003614-63rzzos3	323	13	multiple	multiple	JJ
cord-003614-63rzzos3	323	14	comparison	comparison	NN
cord-003614-63rzzos3	323	15	tests	test	NNS
cord-003614-63rzzos3	323	16	comparing	compare	VBG
cord-003614-63rzzos3	323	17	groups	group	NNS
cord-003614-63rzzos3	323	18	2	2	CD
cord-003614-63rzzos3	323	19	-	-	SYM
cord-003614-63rzzos3	323	20	5	5	CD
cord-003614-63rzzos3	323	21	(	(	-LRB-
cord-003614-63rzzos3	323	22	CDV	CDV	NNP
cord-003614-63rzzos3	323	23	-	-	HYPH
cord-003614-63rzzos3	323	24	infected	infect	VBN
cord-003614-63rzzos3	323	25	)	)	-RRB-
cord-003614-63rzzos3	323	26	with	with	IN
cord-003614-63rzzos3	323	27	group	group	NN
cord-003614-63rzzos3	323	28	1	1	CD
cord-003614-63rzzos3	323	29	(	(	-LRB-
cord-003614-63rzzos3	323	30	control	control	NN
cord-003614-63rzzos3	323	31	)	)	-RRB-
cord-003614-63rzzos3	323	32	.	.	.
cord-003614-63rzzos3	324	1	Spearman	Spearman	NNP
cord-003614-63rzzos3	324	2	's	's	POS
cord-003614-63rzzos3	324	3	rank	rank	NN
cord-003614-63rzzos3	324	4	coefficients	coefficient	NNS
cord-003614-63rzzos3	324	5	were	be	VBD
cord-003614-63rzzos3	324	6	calculated	calculate	VBN
cord-003614-63rzzos3	324	7	to	to	TO
cord-003614-63rzzos3	324	8	evaluate	evaluate	VB
cord-003614-63rzzos3	324	9	the	the	DT
cord-003614-63rzzos3	324	10	correlation	correlation	NN
cord-003614-63rzzos3	324	11	of	of	IN
cord-003614-63rzzos3	324	12	CDV	CDV	NNP
cord-003614-63rzzos3	324	13	antigen	antigen	NN
cord-003614-63rzzos3	324	14	and	and	CC
cord-003614-63rzzos3	324	15	ISG	ISG	NNP
cord-003614-63rzzos3	324	16	protein	protein	NN
cord-003614-63rzzos3	324	17	expression	expression	NN
cord-003614-63rzzos3	324	18	.	.	.
cord-003614-63rzzos3	325	1	Statistical	statistical	JJ
cord-003614-63rzzos3	325	2	significance	significance	NN
cord-003614-63rzzos3	325	3	was	be	VBD
cord-003614-63rzzos3	325	4	designated	designate	VBN
cord-003614-63rzzos3	325	5	as	as	IN
cord-003614-63rzzos3	325	6	p	p	NN
cord-003614-63rzzos3	325	7	<	<	XX
cord-003614-63rzzos3	325	8	0.05	0.05	CD
cord-003614-63rzzos3	325	9	.	.	.
cord-003614-63rzzos3	326	1	The	the	DT
cord-003614-63rzzos3	326	2	IFN	IFN	NNP
cord-003614-63rzzos3	326	3	-	-	HYPH
cord-003614-63rzzos3	326	4	I	-PRON-	PRP
cord-003614-63rzzos3	326	5	pathway	pathway	NN
cord-003614-63rzzos3	326	6	is	be	VBZ
cord-003614-63rzzos3	326	7	activated	activate	VBN
cord-003614-63rzzos3	326	8	in	in	IN
cord-003614-63rzzos3	326	9	the	the	DT
cord-003614-63rzzos3	326	10	early	early	JJ
cord-003614-63rzzos3	326	11	stages	stage	NNS
cord-003614-63rzzos3	326	12	of	of	IN
cord-003614-63rzzos3	326	13	CDV	CDV	NNP
cord-003614-63rzzos3	326	14	-	-	HYPH
cord-003614-63rzzos3	326	15	induced	induce	VBN
cord-003614-63rzzos3	326	16	leukoencephalitis	leukoencephalitis	NNP
cord-003614-63rzzos3	326	17	,	,	,
cord-003614-63rzzos3	326	18	leading	lead	VBG
cord-003614-63rzzos3	326	19	to	to	IN
cord-003614-63rzzos3	326	20	the	the	DT
cord-003614-63rzzos3	326	21	expression	expression	NN
cord-003614-63rzzos3	326	22	of	of	IN
cord-003614-63rzzos3	326	23	various	various	JJ
cord-003614-63rzzos3	326	24	ISGs	isg	NNS
cord-003614-63rzzos3	326	25	,	,	,
cord-003614-63rzzos3	326	26	which	which	WDT
cord-003614-63rzzos3	326	27	restrict	restrict	VBP
cord-003614-63rzzos3	326	28	viral	viral	JJ
cord-003614-63rzzos3	326	29	replication	replication	NN
cord-003614-63rzzos3	326	30	particularly	particularly	RB
cord-003614-63rzzos3	326	31	,	,	,
cord-003614-63rzzos3	326	32	in	in	IN
cord-003614-63rzzos3	326	33	neurons	neuron	NNS
cord-003614-63rzzos3	326	34	and	and	CC
cord-003614-63rzzos3	326	35	oligodendrocytes	oligodendrocyte	NNS
cord-003614-63rzzos3	326	36	.	.	.
cord-003614-63rzzos3	327	1	In	in	IN
cord-003614-63rzzos3	327	2	contrast	contrast	NN
cord-003614-63rzzos3	327	3	,	,	,
cord-003614-63rzzos3	327	4	the	the	DT
cord-003614-63rzzos3	327	5	lack	lack	NN
cord-003614-63rzzos3	327	6	of	of	IN
cord-003614-63rzzos3	327	7	STAT2	STAT2	NNS
cord-003614-63rzzos3	327	8	expression	expression	NN
cord-003614-63rzzos3	327	9	in	in	IN
cord-003614-63rzzos3	327	10	astrocytes	astrocyte	NNS
cord-003614-63rzzos3	327	11	and	and	CC
cord-003614-63rzzos3	327	12	subsequent	subsequent	JJ
cord-003614-63rzzos3	327	13	suppression	suppression	NN
cord-003614-63rzzos3	327	14	of	of	IN
cord-003614-63rzzos3	327	15	canonical	canonical	JJ
cord-003614-63rzzos3	327	16	JAK	JAK	NNP
cord-003614-63rzzos3	327	17	-	-	HYPH
cord-003614-63rzzos3	327	18	STAT	STAT	NNP
cord-003614-63rzzos3	327	19	signaling	signaling	NN
cord-003614-63rzzos3	327	20	might	may	MD
cord-003614-63rzzos3	327	21	explain	explain	VB
cord-003614-63rzzos3	327	22	their	-PRON-	PRP$
cord-003614-63rzzos3	327	23	high	high	JJ
cord-003614-63rzzos3	327	24	infection	infection	NN
cord-003614-63rzzos3	327	25	rate	rate	NN
cord-003614-63rzzos3	327	26	in	in	IN
cord-003614-63rzzos3	327	27	cerebellar	cerebellar	JJ
cord-003614-63rzzos3	327	28	lesions	lesion	NNS
cord-003614-63rzzos3	327	29	.	.	.
cord-003614-63rzzos3	328	1	The	the	DT
cord-003614-63rzzos3	328	2	up	up	JJ
cord-003614-63rzzos3	328	3	-	-	HYPH
cord-003614-63rzzos3	328	4	regulation	regulation	NN
cord-003614-63rzzos3	328	5	of	of	IN
cord-003614-63rzzos3	328	6	ISGs	ISGs	NNPS
cord-003614-63rzzos3	328	7	seems	seem	VBZ
cord-003614-63rzzos3	328	8	to	to	TO
cord-003614-63rzzos3	328	9	be	be	VB
cord-003614-63rzzos3	328	10	partly	partly	RB
cord-003614-63rzzos3	328	11	mediated	mediate	VBN
cord-003614-63rzzos3	328	12	by	by	IN
cord-003614-63rzzos3	328	13	IRF1-and	IRF1-and	NNP
cord-003614-63rzzos3	328	14	IRF7-dependent	IRF7-dependent	NNP
cord-003614-63rzzos3	328	15	pathways	pathway	NNS
cord-003614-63rzzos3	328	16	counteracting	counteract	VBG
cord-003614-63rzzos3	328	17	the	the	DT
cord-003614-63rzzos3	328	18	inhibition	inhibition	NN
cord-003614-63rzzos3	328	19	of	of	IN
cord-003614-63rzzos3	328	20	the	the	DT
cord-003614-63rzzos3	328	21	IFN	IFN	NNP
cord-003614-63rzzos3	328	22	-	-	HYPH
cord-003614-63rzzos3	328	23	I	-PRON-	PRP
cord-003614-63rzzos3	328	24	response	response	NN
cord-003614-63rzzos3	328	25	by	by	IN
cord-003614-63rzzos3	328	26	CDV	CDV	NNP
cord-003614-63rzzos3	328	27	.	.	.
cord-003614-63rzzos3	329	1	However	however	RB
cord-003614-63rzzos3	329	2	,	,	,
cord-003614-63rzzos3	329	3	the	the	DT
cord-003614-63rzzos3	329	4	strong	strong	JJ
cord-003614-63rzzos3	329	5	activation	activation	NN
cord-003614-63rzzos3	329	6	of	of	IN
cord-003614-63rzzos3	329	7	the	the	DT
cord-003614-63rzzos3	329	8	IFN	IFN	NNP
cord-003614-63rzzos3	329	9	-	-	HYPH
cord-003614-63rzzos3	329	10	I	I	NNP
cord-003614-63rzzos3	329	11	signaling	signal	VBG
cord-003614-63rzzos3	329	12	cascade	cascade	NN
cord-003614-63rzzos3	329	13	,	,	,
cord-003614-63rzzos3	329	14	especially	especially	RB
cord-003614-63rzzos3	329	15	in	in	IN
cord-003614-63rzzos3	329	16	activated	activate	VBN
cord-003614-63rzzos3	329	17	microglia	microglia	NNS
cord-003614-63rzzos3	329	18	/	/	SYM
cord-003614-63rzzos3	329	19	macrophages	macrophage	NNS
cord-003614-63rzzos3	329	20	,	,	,
cord-003614-63rzzos3	329	21	probably	probably	RB
cord-003614-63rzzos3	329	22	contributes	contribute	VBZ
cord-003614-63rzzos3	329	23	to	to	IN
cord-003614-63rzzos3	329	24	immune	immune	JJ
cord-003614-63rzzos3	329	25	-	-	HYPH
cord-003614-63rzzos3	329	26	mediated	mediate	VBN
cord-003614-63rzzos3	329	27	mechanisms	mechanism	NNS
cord-003614-63rzzos3	329	28	of	of	IN
cord-003614-63rzzos3	329	29	demyelination	demyelination	NN
cord-003614-63rzzos3	329	30	in	in	IN
cord-003614-63rzzos3	329	31	later	later	JJ
cord-003614-63rzzos3	329	32	stages	stage	NNS
cord-003614-63rzzos3	329	33	of	of	IN
cord-003614-63rzzos3	329	34	the	the	DT
cord-003614-63rzzos3	329	35	disease	disease	NN
cord-003614-63rzzos3	329	36	.	.	.
cord-003614-63rzzos3	330	1	These	these	DT
cord-003614-63rzzos3	330	2	results	result	NNS
cord-003614-63rzzos3	330	3	encourage	encourage	VBP
cord-003614-63rzzos3	330	4	further	further	JJ
cord-003614-63rzzos3	330	5	research	research	NN
cord-003614-63rzzos3	330	6	to	to	TO
cord-003614-63rzzos3	330	7	elucidate	elucidate	VB
cord-003614-63rzzos3	330	8	the	the	DT
cord-003614-63rzzos3	330	9	regulation	regulation	NN
cord-003614-63rzzos3	330	10	of	of	IN
cord-003614-63rzzos3	330	11	IFN	IFN	NNP
cord-003614-63rzzos3	330	12	-	-	:
cord-003614-63rzzos3	330	13	I	I	NNP
cord-003614-63rzzos3	330	14	signaling	signal	VBG
cord-003614-63rzzos3	330	15	and	and	CC
cord-003614-63rzzos3	330	16	its	-PRON-	PRP$
cord-003614-63rzzos3	330	17	contribution	contribution	NN
cord-003614-63rzzos3	330	18	to	to	IN
cord-003614-63rzzos3	330	19	demyelinating	demyelinate	VBG
cord-003614-63rzzos3	330	20	CNS	CNS	NNP
cord-003614-63rzzos3	330	21	diseases	disease	NNS
cord-003614-63rzzos3	330	22	in	in	IN
cord-003614-63rzzos3	330	23	dogs	dog	NNS
cord-003614-63rzzos3	330	24	and	and	CC
cord-003614-63rzzos3	330	25	humans	human	NNS
cord-003614-63rzzos3	330	26	in	in	IN
cord-003614-63rzzos3	330	27	order	order	NN
cord-003614-63rzzos3	330	28	to	to	TO
cord-003614-63rzzos3	330	29	develop	develop	VB
cord-003614-63rzzos3	330	30	novel	novel	JJ
cord-003614-63rzzos3	330	31	treatment	treatment	NN
cord-003614-63rzzos3	330	32	strategies	strategy	NNS
cord-003614-63rzzos3	330	33	targeting	target	VBG
cord-003614-63rzzos3	330	34	specific	specific	JJ
cord-003614-63rzzos3	330	35	IFN	IFN	NNP
cord-003614-63rzzos3	330	36	-	-	HYPH
cord-003614-63rzzos3	330	37	I	I	NNP
cord-003614-63rzzos3	330	38	pathway	pathway	NN
cord-003614-63rzzos3	330	39	members	member	NNS
cord-003614-63rzzos3	330	40	.	.	.
cord-003614-63rzzos3	331	1	The	the	DT
cord-003614-63rzzos3	331	2	authors	author	NNS
cord-003614-63rzzos3	331	3	declare	declare	VBP
cord-003614-63rzzos3	331	4	no	no	DT
cord-003614-63rzzos3	331	5	potential	potential	JJ
cord-003614-63rzzos3	331	6	conflicts	conflict	NNS
cord-003614-63rzzos3	331	7	of	of	IN
cord-003614-63rzzos3	331	8	interest	interest	NN
cord-003614-63rzzos3	331	9	with	with	IN
cord-003614-63rzzos3	331	10	respect	respect	NN
cord-003614-63rzzos3	331	11	to	to	IN
cord-003614-63rzzos3	331	12	the	the	DT
cord-003614-63rzzos3	331	13	research	research	NN
cord-003614-63rzzos3	331	14	,	,	,
cord-003614-63rzzos3	331	15	authorship	authorship	NN
cord-003614-63rzzos3	331	16	,	,	,
cord-003614-63rzzos3	331	17	and/or	and/or	CC
cord-003614-63rzzos3	331	18	publication	publication	NN
cord-003614-63rzzos3	331	19	of	of	IN
cord-003614-63rzzos3	331	20	this	this	DT
cord-003614-63rzzos3	331	21	article	article	NN
cord-003614-63rzzos3	331	22	.	.	.
cord-003614-63rzzos3	332	1	Matrix	matrix	NN
cord-003614-63rzzos3	332	2	genes	gene	NNS
cord-003614-63rzzos3	332	3	of	of	IN
cord-003614-63rzzos3	332	4	measles	measle	NNS
cord-003614-63rzzos3	332	5	virus	virus	NN
cord-003614-63rzzos3	332	6	and	and	CC
cord-003614-63rzzos3	332	7	canine	canine	JJ
cord-003614-63rzzos3	332	8	distemper	distemper	NN
cord-003614-63rzzos3	332	9	virus	virus	NN
cord-003614-63rzzos3	332	10	:	:	:
cord-003614-63rzzos3	332	11	Cloning	cloning	NN
cord-003614-63rzzos3	332	12	,	,	,
cord-003614-63rzzos3	332	13	nucleotide	nucleotide	JJ
cord-003614-63rzzos3	332	14	sequences	sequence	NNS
cord-003614-63rzzos3	332	15	,	,	,
cord-003614-63rzzos3	332	16	and	and	CC
cord-003614-63rzzos3	332	17	deduced	deduce	VBD
cord-003614-63rzzos3	332	18	amino	amino	NN
cord-003614-63rzzos3	332	19	acid	acid	NN
cord-003614-63rzzos3	332	20	sequences	sequence	NNS
cord-003614-63rzzos3	332	21	New	new	JJ
cord-003614-63rzzos3	332	22	aspects	aspect	NNS
cord-003614-63rzzos3	332	23	of	of	IN
cord-003614-63rzzos3	332	24	the	the	DT
cord-003614-63rzzos3	332	25	pathogenesis	pathogenesis	NN
cord-003614-63rzzos3	332	26	of	of	IN
cord-003614-63rzzos3	332	27	canine	canine	JJ
cord-003614-63rzzos3	332	28	distemper	distemper	NN
cord-003614-63rzzos3	332	29	leukoencephalitis	leukoencephalitis	NN
cord-003614-63rzzos3	332	30	Demyelination	Demyelination	NNP
cord-003614-63rzzos3	332	31	in	in	IN
cord-003614-63rzzos3	332	32	canine	canine	JJ
cord-003614-63rzzos3	332	33	distemper	distemper	NN
cord-003614-63rzzos3	332	34	virus	virus	NN
cord-003614-63rzzos3	332	35	infection	infection	NN
cord-003614-63rzzos3	332	36	:	:	:
cord-003614-63rzzos3	332	37	A	a	DT
cord-003614-63rzzos3	332	38	review	review	NN
cord-003614-63rzzos3	332	39	Pathogenesis	pathogenesis	NN
cord-003614-63rzzos3	332	40	and	and	CC
cord-003614-63rzzos3	332	41	immunopathology	immunopathology	NN
cord-003614-63rzzos3	332	42	of	of	IN
cord-003614-63rzzos3	332	43	systemic	systemic	JJ
cord-003614-63rzzos3	332	44	and	and	CC
cord-003614-63rzzos3	332	45	nervous	nervous	JJ
cord-003614-63rzzos3	332	46	canine	canine	JJ
cord-003614-63rzzos3	332	47	distemper	distemper	NN
cord-003614-63rzzos3	332	48	Virale	Virale	NNP
cord-003614-63rzzos3	332	49	Infektionen	Infektionen	NNP
cord-003614-63rzzos3	332	50	von	von	NNP
cord-003614-63rzzos3	332	51	Welpen	Welpen	NNP
cord-003614-63rzzos3	332	52	und	und	IN
cord-003614-63rzzos3	332	53	Junghunden	Junghunden	NNP
cord-003614-63rzzos3	332	54	unter	unter	NNP
cord-003614-63rzzos3	333	1	Berücksichtigung	Berücksichtigung	NNP
cord-003614-63rzzos3	333	2	der	der	NNP
cord-003614-63rzzos3	333	3	Staupevirusinfektion	Staupevirusinfektion	NNP
cord-003614-63rzzos3	333	4	Abundant	abundant	JJ
cord-003614-63rzzos3	333	5	expression	expression	NN
cord-003614-63rzzos3	333	6	of	of	IN
cord-003614-63rzzos3	333	7	viral	viral	JJ
cord-003614-63rzzos3	333	8	nucleoprotein	nucleoprotein	NNP
cord-003614-63rzzos3	333	9	mRNA	mRNA	NNP
cord-003614-63rzzos3	333	10	and	and	CC
cord-003614-63rzzos3	333	11	restricted	restricted	JJ
cord-003614-63rzzos3	333	12	translation	translation	NN
cord-003614-63rzzos3	333	13	of	of	IN
cord-003614-63rzzos3	333	14	the	the	DT
cord-003614-63rzzos3	333	15	corresponding	corresponding	JJ
cord-003614-63rzzos3	333	16	viral	viral	JJ
cord-003614-63rzzos3	333	17	protein	protein	NN
cord-003614-63rzzos3	333	18	in	in	IN
cord-003614-63rzzos3	333	19	inclusion	inclusion	NN
cord-003614-63rzzos3	333	20	body	body	NN
cord-003614-63rzzos3	333	21	polioencephalitis	polioencephalitis	NN
cord-003614-63rzzos3	333	22	of	of	IN
cord-003614-63rzzos3	333	23	canine	canine	JJ
cord-003614-63rzzos3	333	24	distemper	distemper	NN
cord-003614-63rzzos3	333	25	Restricted	restrict	VBN
cord-003614-63rzzos3	333	26	virus	virus	NN
cord-003614-63rzzos3	333	27	protein	protein	NN
cord-003614-63rzzos3	333	28	translation	translation	NN
cord-003614-63rzzos3	333	29	in	in	IN
cord-003614-63rzzos3	333	30	canine	canine	JJ
cord-003614-63rzzos3	333	31	distemper	distemper	NN
cord-003614-63rzzos3	333	32	virus	virus	NN
cord-003614-63rzzos3	333	33	inclusion	inclusion	NN
cord-003614-63rzzos3	333	34	body	body	NN
cord-003614-63rzzos3	333	35	polioencephalitis	polioencephalitis	NN
cord-003614-63rzzos3	333	36	Demyelination	Demyelination	NNP
cord-003614-63rzzos3	333	37	in	in	IN
cord-003614-63rzzos3	333	38	experimental	experimental	JJ
cord-003614-63rzzos3	333	39	canine	canine	JJ
cord-003614-63rzzos3	333	40	distemper	distemper	NN
cord-003614-63rzzos3	333	41	virus	virus	NN
cord-003614-63rzzos3	333	42	infection	infection	NN
cord-003614-63rzzos3	333	43	:	:	:
cord-003614-63rzzos3	334	1	Immunological	immunological	JJ
cord-003614-63rzzos3	334	2	,	,	,
cord-003614-63rzzos3	334	3	pathologic	pathologic	JJ
cord-003614-63rzzos3	334	4	,	,	,
cord-003614-63rzzos3	334	5	and	and	CC
cord-003614-63rzzos3	334	6	immunohistological	immunohistological	NNP
cord-003614-63rzzos3	334	7	studies	study	NNS
cord-003614-63rzzos3	335	1	The	the	DT
cord-003614-63rzzos3	335	2	Pathogenesis	Pathogenesis	NNP
cord-003614-63rzzos3	335	3	of	of	IN
cord-003614-63rzzos3	335	4	Canine	Canine	NNP
cord-003614-63rzzos3	335	5	Distemper	Distemper	NNP
cord-003614-63rzzos3	335	6	Virus	virus	NN
cord-003614-63rzzos3	335	7	Induced	induce	VBN
cord-003614-63rzzos3	335	8	Demyelination	Demyelination	NNP
cord-003614-63rzzos3	335	9	Aspects	aspect	NNS
cord-003614-63rzzos3	335	10	of	of	IN
cord-003614-63rzzos3	335	11	canine	canine	JJ
cord-003614-63rzzos3	335	12	distemper	distemper	NN
cord-003614-63rzzos3	335	13	virus	virus	NN
cord-003614-63rzzos3	335	14	and	and	CC
cord-003614-63rzzos3	335	15	measles	measles	NN
cord-003614-63rzzos3	335	16	virus	virus	NN
cord-003614-63rzzos3	335	17	encephalomyelitis	encephalomyelitis	NN
cord-003614-63rzzos3	335	18	Class	Class	NNP
cord-003614-63rzzos3	335	19	II	II	NNP
cord-003614-63rzzos3	335	20	cytokine	cytokine	NN
cord-003614-63rzzos3	335	21	receptors	receptor	NNS
cord-003614-63rzzos3	335	22	and	and	CC
cord-003614-63rzzos3	335	23	their	-PRON-	PRP$
cord-003614-63rzzos3	335	24	ligands	ligand	NNS
cord-003614-63rzzos3	335	25	:	:	:
cord-003614-63rzzos3	335	26	Key	key	JJ
cord-003614-63rzzos3	335	27	antiviral	antiviral	JJ
cord-003614-63rzzos3	335	28	and	and	CC
cord-003614-63rzzos3	335	29	inflammatory	inflammatory	JJ
cord-003614-63rzzos3	335	30	modulators	modulator	NNS
cord-003614-63rzzos3	336	1	Interferon	interferon	NN
cord-003614-63rzzos3	336	2	-	-	HYPH
cord-003614-63rzzos3	336	3	stimulated	stimulate	VBN
cord-003614-63rzzos3	336	4	genes	gene	NNS
cord-003614-63rzzos3	336	5	and	and	CC
cord-003614-63rzzos3	336	6	their	-PRON-	PRP$
cord-003614-63rzzos3	336	7	antiviral	antiviral	JJ
cord-003614-63rzzos3	336	8	effector	effector	NN
cord-003614-63rzzos3	336	9	functions	function	NNS
cord-003614-63rzzos3	336	10	Role	role	NN
cord-003614-63rzzos3	336	11	of	of	IN
cord-003614-63rzzos3	336	12	early	early	JJ
cord-003614-63rzzos3	336	13	cytokines	cytokine	NNS
cord-003614-63rzzos3	336	14	,	,	,
cord-003614-63rzzos3	336	15	including	include	VBG
cord-003614-63rzzos3	336	16	alpha	alpha	NN
cord-003614-63rzzos3	336	17	and	and	CC
cord-003614-63rzzos3	336	18	beta	beta	NN
cord-003614-63rzzos3	336	19	interferons	interferon	NNS
cord-003614-63rzzos3	336	20	(	(	-LRB-
cord-003614-63rzzos3	336	21	IFN	IFN	NNP
cord-003614-63rzzos3	336	22	-	-	HYPH
cord-003614-63rzzos3	336	23	alpha	alpha	NN
cord-003614-63rzzos3	336	24	/	/	SYM
cord-003614-63rzzos3	336	25	beta	beta	NN
cord-003614-63rzzos3	336	26	)	)	-RRB-
cord-003614-63rzzos3	336	27	,	,	,
cord-003614-63rzzos3	336	28	in	in	IN
cord-003614-63rzzos3	336	29	innate	innate	JJ
cord-003614-63rzzos3	336	30	and	and	CC
cord-003614-63rzzos3	336	31	adaptive	adaptive	JJ
cord-003614-63rzzos3	336	32	immune	immune	JJ
cord-003614-63rzzos3	336	33	responses	response	NNS
cord-003614-63rzzos3	336	34	to	to	IN
cord-003614-63rzzos3	336	35	viral	viral	JJ
cord-003614-63rzzos3	336	36	infections	infection	NNS
cord-003614-63rzzos3	336	37	Gerhauser	Gerhauser	NNP
cord-003614-63rzzos3	336	38	,	,	,
cord-003614-63rzzos3	337	1	I.	I.	NNP
cord-003614-63rzzos3	337	2	Type	type	NN
cord-003614-63rzzos3	338	1	I	-PRON-	PRP
cord-003614-63rzzos3	338	2	interferons	interferon	NNS
cord-003614-63rzzos3	338	3	in	in	IN
cord-003614-63rzzos3	338	4	the	the	DT
cord-003614-63rzzos3	338	5	pathogenesis	pathogenesis	NN
cord-003614-63rzzos3	338	6	and	and	CC
cord-003614-63rzzos3	338	7	treatment	treatment	NN
cord-003614-63rzzos3	338	8	of	of	IN
cord-003614-63rzzos3	338	9	canine	canine	JJ
cord-003614-63rzzos3	338	10	diseases	disease	NNS
cord-003614-63rzzos3	339	1	Interferon	interferon	NN
cord-003614-63rzzos3	339	2	-	-	HYPH
cord-003614-63rzzos3	339	3	γ	γ	NN
cord-003614-63rzzos3	339	4	:	:	:
cord-003614-63rzzos3	340	1	Gene	Gene	NNP
cord-003614-63rzzos3	340	2	and	and	CC
cord-003614-63rzzos3	340	3	Protein	Protein	NNP
cord-003614-63rzzos3	340	4	Structure	Structure	NNP
cord-003614-63rzzos3	340	5	,	,	,
cord-003614-63rzzos3	340	6	Transcription	Transcription	NNP
cord-003614-63rzzos3	340	7	Regulation	Regulation	NNP
cord-003614-63rzzos3	340	8	,	,	,
cord-003614-63rzzos3	340	9	and	and	CC
cord-003614-63rzzos3	340	10	Actions	action	NNS
cord-003614-63rzzos3	341	1	Interferon	interferon	NN
cord-003614-63rzzos3	341	2	-	-	HYPH
cord-003614-63rzzos3	341	3	lambda	lambda	NN
cord-003614-63rzzos3	341	4	:	:	:
cord-003614-63rzzos3	341	5	A	a	DT
cord-003614-63rzzos3	341	6	new	new	JJ
cord-003614-63rzzos3	341	7	addition	addition	NN
cord-003614-63rzzos3	341	8	to	to	IN
cord-003614-63rzzos3	341	9	an	an	DT
cord-003614-63rzzos3	341	10	old	old	JJ
cord-003614-63rzzos3	341	11	family	family	NN
cord-003614-63rzzos3	341	12	Functional	functional	JJ
cord-003614-63rzzos3	341	13	characterization	characterization	NN
cord-003614-63rzzos3	341	14	of	of	IN
cord-003614-63rzzos3	341	15	canine	canine	JJ
cord-003614-63rzzos3	341	16	interferon	interferon	NN
cord-003614-63rzzos3	341	17	-	-	HYPH
cord-003614-63rzzos3	341	18	lambda	lambda	NNP
cord-003614-63rzzos3	341	19	Antiviral	Antiviral	NNP
cord-003614-63rzzos3	341	20	and	and	CC
cord-003614-63rzzos3	341	21	antiproliferative	antiproliferative	JJ
cord-003614-63rzzos3	341	22	effects	effect	NNS
cord-003614-63rzzos3	341	23	of	of	IN
cord-003614-63rzzos3	341	24	canine	canine	JJ
cord-003614-63rzzos3	341	25	interferon	interferon	NN
cord-003614-63rzzos3	341	26	-	-	HYPH
cord-003614-63rzzos3	341	27	lambda1	lambda1	NN
cord-003614-63rzzos3	341	28	IFN	IFN	NNP
cord-003614-63rzzos3	341	29	-	-	HYPH
cord-003614-63rzzos3	341	30	lambdas	lambda	NNS
cord-003614-63rzzos3	341	31	mediate	mediate	VBP
cord-003614-63rzzos3	341	32	antiviral	antiviral	JJ
cord-003614-63rzzos3	341	33	protection	protection	NN
cord-003614-63rzzos3	341	34	through	through	IN
cord-003614-63rzzos3	341	35	a	a	DT
cord-003614-63rzzos3	341	36	distinct	distinct	JJ
cord-003614-63rzzos3	341	37	class	class	NN
cord-003614-63rzzos3	341	38	II	ii	NN
cord-003614-63rzzos3	341	39	cytokine	cytokine	NN
cord-003614-63rzzos3	341	40	receptor	receptor	NN
cord-003614-63rzzos3	341	41	complex	complex	JJ
cord-003614-63rzzos3	341	42	Integrative	integrative	JJ
cord-003614-63rzzos3	341	43	genomic	genomic	JJ
cord-003614-63rzzos3	341	44	analyses	analysis	NNS
cord-003614-63rzzos3	341	45	on	on	IN
cord-003614-63rzzos3	341	46	interferon	interferon	NN
cord-003614-63rzzos3	341	47	-	-	HYPH
cord-003614-63rzzos3	341	48	lambdas	lambda	NNS
cord-003614-63rzzos3	341	49	and	and	CC
cord-003614-63rzzos3	341	50	their	-PRON-	PRP$
cord-003614-63rzzos3	341	51	roles	role	NNS
cord-003614-63rzzos3	341	52	in	in	IN
cord-003614-63rzzos3	341	53	cancer	cancer	NN
cord-003614-63rzzos3	341	54	prediction	prediction	NN
cord-003614-63rzzos3	341	55	Independent	Independent	NNP
cord-003614-63rzzos3	341	56	Comparison	Comparison	NNP
cord-003614-63rzzos3	341	57	of	of	IN
cord-003614-63rzzos3	341	58	Interferon	Interferon	NNP
cord-003614-63rzzos3	341	59	Trial	Trial	NNP
cord-003614-63rzzos3	341	60	Study	Study	NNP
cord-003614-63rzzos3	341	61	,	,	,
cord-003614-63rzzos3	341	62	G.	G.	NNP
cord-003614-63rzzos3	341	63	Every	Every	NNP
cord-003614-63rzzos3	341	64	-	-	HYPH
cord-003614-63rzzos3	341	65	other	other	JJ
cord-003614-63rzzos3	341	66	-	-	HYPH
cord-003614-63rzzos3	341	67	day	day	NN
cord-003614-63rzzos3	342	1	interferon	interferon	NN
cord-003614-63rzzos3	342	2	beta-1b	beta-1b	VBZ
cord-003614-63rzzos3	342	3	versus	versus	IN
cord-003614-63rzzos3	342	4	once	once	RB
cord-003614-63rzzos3	342	5	-	-	HYPH
cord-003614-63rzzos3	342	6	weekly	weekly	NN
cord-003614-63rzzos3	342	7	interferon	interferon	NN
cord-003614-63rzzos3	342	8	beta-1a	beta-1a	NNP
cord-003614-63rzzos3	342	9	for	for	IN
cord-003614-63rzzos3	342	10	multiple	multiple	JJ
cord-003614-63rzzos3	342	11	sclerosis	sclerosis	NN
cord-003614-63rzzos3	342	12	:	:	:
cord-003614-63rzzos3	342	13	Results	result	NNS
cord-003614-63rzzos3	342	14	of	of	IN
cord-003614-63rzzos3	342	15	a	a	DT
cord-003614-63rzzos3	342	16	2-year	2-year	CD
cord-003614-63rzzos3	342	17	prospective	prospective	JJ
cord-003614-63rzzos3	342	18	randomised	randomised	JJ
cord-003614-63rzzos3	342	19	multicentre	multicentre	NNP
cord-003614-63rzzos3	342	20	study	study	NN
cord-003614-63rzzos3	342	21	(	(	-LRB-
cord-003614-63rzzos3	342	22	INCOMIN	INCOMIN	NNP
cord-003614-63rzzos3	342	23	)	)	-RRB-
cord-003614-63rzzos3	342	24	Pathology	Pathology	NNP
cord-003614-63rzzos3	342	25	in	in	IN
cord-003614-63rzzos3	342	26	practice	practice	NN
cord-003614-63rzzos3	342	27	.	.	.
cord-003614-63rzzos3	343	1	Canine	canine	JJ
cord-003614-63rzzos3	343	2	distemper	distemper	NN
cord-003614-63rzzos3	343	3	virus	virus	NN
cord-003614-63rzzos3	343	4	disease	disease	NN
cord-003614-63rzzos3	343	5	in	in	IN
cord-003614-63rzzos3	343	6	a	a	DT
cord-003614-63rzzos3	343	7	dog	dog	NN
cord-003614-63rzzos3	343	8	Pattern	pattern	NN
cord-003614-63rzzos3	343	9	recognition	recognition	NN
cord-003614-63rzzos3	343	10	receptors	receptor	NNS
cord-003614-63rzzos3	343	11	and	and	CC
cord-003614-63rzzos3	343	12	inflammation	inflammation	NN
cord-003614-63rzzos3	343	13	Pattern	pattern	NN
cord-003614-63rzzos3	343	14	recognition	recognition	NN
cord-003614-63rzzos3	343	15	receptors	receptor	NNS
cord-003614-63rzzos3	343	16	and	and	CC
cord-003614-63rzzos3	343	17	the	the	DT
cord-003614-63rzzos3	343	18	innate	innate	JJ
cord-003614-63rzzos3	343	19	immune	immune	JJ
cord-003614-63rzzos3	343	20	response	response	NN
cord-003614-63rzzos3	343	21	to	to	IN
cord-003614-63rzzos3	343	22	viral	viral	JJ
cord-003614-63rzzos3	343	23	infection	infection	NN
cord-003614-63rzzos3	344	1	Innate	innate	JJ
cord-003614-63rzzos3	344	2	immune	immune	JJ
cord-003614-63rzzos3	344	3	recognition	recognition	NN
cord-003614-63rzzos3	344	4	:	:	:
cord-003614-63rzzos3	344	5	Mechanisms	mechanism	NNS
cord-003614-63rzzos3	344	6	and	and	CC
cord-003614-63rzzos3	344	7	pathways	pathway	NNS
cord-003614-63rzzos3	345	1	Innate	innate	JJ
cord-003614-63rzzos3	345	2	immunity	immunity	NN
cord-003614-63rzzos3	345	3	:	:	:
cord-003614-63rzzos3	345	4	The	the	DT
cord-003614-63rzzos3	345	5	virtues	virtue	NNS
cord-003614-63rzzos3	345	6	of	of	IN
cord-003614-63rzzos3	345	7	a	a	DT
cord-003614-63rzzos3	345	8	nonclonal	nonclonal	JJ
cord-003614-63rzzos3	345	9	system	system	NN
cord-003614-63rzzos3	345	10	of	of	IN
cord-003614-63rzzos3	345	11	recognition	recognition	NN
cord-003614-63rzzos3	345	12	Mechanisms	Mechanisms	NNPS
cord-003614-63rzzos3	345	13	and	and	CC
cord-003614-63rzzos3	345	14	pathways	pathway	NNS
cord-003614-63rzzos3	345	15	of	of	IN
cord-003614-63rzzos3	345	16	innate	innate	JJ
cord-003614-63rzzos3	345	17	immune	immune	JJ
cord-003614-63rzzos3	345	18	activation	activation	NN
cord-003614-63rzzos3	345	19	and	and	CC
cord-003614-63rzzos3	345	20	regulation	regulation	NN
cord-003614-63rzzos3	345	21	in	in	IN
cord-003614-63rzzos3	345	22	health	health	NN
cord-003614-63rzzos3	345	23	and	and	CC
cord-003614-63rzzos3	345	24	cancer	cancer	NN
cord-003614-63rzzos3	345	25	Toll	Toll	NNP
cord-003614-63rzzos3	345	26	-	-	HYPH
cord-003614-63rzzos3	345	27	like	like	JJ
cord-003614-63rzzos3	345	28	receptor	receptor	NN
cord-003614-63rzzos3	345	29	signalling	signal	VBG
cord-003614-63rzzos3	345	30	RIG	rig	NN
cord-003614-63rzzos3	345	31	-	-	:
cord-003614-63rzzos3	345	32	I	-PRON-	PRP
cord-003614-63rzzos3	345	33	like	like	VBP
cord-003614-63rzzos3	345	34	receptors	receptor	NNS
cord-003614-63rzzos3	345	35	and	and	CC
cord-003614-63rzzos3	345	36	their	-PRON-	PRP$
cord-003614-63rzzos3	345	37	signaling	signal	VBG
cord-003614-63rzzos3	345	38	crosstalk	crosstalk	NN
cord-003614-63rzzos3	345	39	in	in	IN
cord-003614-63rzzos3	345	40	the	the	DT
cord-003614-63rzzos3	345	41	regulation	regulation	NN
cord-003614-63rzzos3	345	42	of	of	IN
cord-003614-63rzzos3	345	43	antiviral	antiviral	JJ
cord-003614-63rzzos3	345	44	immunity	immunity	NN
cord-003614-63rzzos3	345	45	Interferon	interferon	NN
cord-003614-63rzzos3	345	46	-	-	HYPH
cord-003614-63rzzos3	345	47	inducible	inducible	JJ
cord-003614-63rzzos3	345	48	antiviral	antiviral	JJ
cord-003614-63rzzos3	345	49	effectors	effector	NNS
cord-003614-63rzzos3	345	50	Intrinsic	intrinsic	JJ
cord-003614-63rzzos3	345	51	cellular	cellular	JJ
cord-003614-63rzzos3	345	52	defenses	defense	NNS
cord-003614-63rzzos3	345	53	against	against	IN
cord-003614-63rzzos3	345	54	virus	virus	NN
cord-003614-63rzzos3	345	55	infection	infection	NN
cord-003614-63rzzos3	345	56	by	by	IN
cord-003614-63rzzos3	345	57	antiviral	antiviral	JJ
cord-003614-63rzzos3	345	58	type	type	NN
cord-003614-63rzzos3	346	1	I	-PRON-	PRP
cord-003614-63rzzos3	346	2	interferon	interferon	RB
cord-003614-63rzzos3	347	1	The	the	DT
cord-003614-63rzzos3	347	2	JAK	JAK	NNP
cord-003614-63rzzos3	347	3	-	-	HYPH
cord-003614-63rzzos3	347	4	STAT	stat	NN
cord-003614-63rzzos3	347	5	pathway	pathway	NN
cord-003614-63rzzos3	347	6	at	at	IN
cord-003614-63rzzos3	347	7	twenty	twenty	CD
cord-003614-63rzzos3	348	1	The	the	DT
cord-003614-63rzzos3	348	2	molecular	molecular	JJ
cord-003614-63rzzos3	348	3	details	detail	NNS
cord-003614-63rzzos3	348	4	of	of	IN
cord-003614-63rzzos3	348	5	cytokine	cytokine	NN
cord-003614-63rzzos3	348	6	signaling	signaling	NN
cord-003614-63rzzos3	348	7	via	via	IN
cord-003614-63rzzos3	348	8	the	the	DT
cord-003614-63rzzos3	348	9	JAK	JAK	NNP
cord-003614-63rzzos3	348	10	/	/	SYM
cord-003614-63rzzos3	348	11	STAT	STAT	NNP
cord-003614-63rzzos3	348	12	pathway	pathway	NN
cord-003614-63rzzos3	349	1	The	the	DT
cord-003614-63rzzos3	349	2	interferon	interferon	NN
cord-003614-63rzzos3	349	3	receptors	receptor	NNS
cord-003614-63rzzos3	350	1	Interplay	interplay	NN
cord-003614-63rzzos3	350	2	between	between	IN
cord-003614-63rzzos3	350	3	Janus	Janus	NNP
cord-003614-63rzzos3	350	4	Kinase	Kinase	NNP
cord-003614-63rzzos3	350	5	/	/	SYM
cord-003614-63rzzos3	350	6	Signal	Signal	NNP
cord-003614-63rzzos3	350	7	Transducer	Transducer	NNP
cord-003614-63rzzos3	350	8	and	and	CC
cord-003614-63rzzos3	350	9	Activator	Activator	NNP
cord-003614-63rzzos3	350	10	of	of	IN
cord-003614-63rzzos3	350	11	Transcription	Transcription	NNP
cord-003614-63rzzos3	350	12	Signaling	Signaling	NNP
cord-003614-63rzzos3	350	13	Activated	activate	VBN
cord-003614-63rzzos3	350	14	by	by	IN
cord-003614-63rzzos3	350	15	Type	type	NN
cord-003614-63rzzos3	350	16	I	-PRON-	PRP
cord-003614-63rzzos3	350	17	Interferons	Interferons	NNPS
cord-003614-63rzzos3	350	18	and	and	CC
cord-003614-63rzzos3	350	19	Viral	Viral	NNP
cord-003614-63rzzos3	350	20	Antagonism	Antagonism	NNP
cord-003614-63rzzos3	351	1	Interferon	interferon	NN
cord-003614-63rzzos3	351	2	-	-	HYPH
cord-003614-63rzzos3	351	3	induced	induce	VBN
cord-003614-63rzzos3	351	4	nuclear	nuclear	JJ
cord-003614-63rzzos3	351	5	factors	factor	NNS
cord-003614-63rzzos3	351	6	that	that	WDT
cord-003614-63rzzos3	351	7	bind	bind	VBP
cord-003614-63rzzos3	351	8	a	a	DT
cord-003614-63rzzos3	351	9	shared	share	VBN
cord-003614-63rzzos3	351	10	promoter	promoter	NN
cord-003614-63rzzos3	351	11	element	element	NN
cord-003614-63rzzos3	351	12	correlate	correlate	VBP
cord-003614-63rzzos3	351	13	with	with	IN
cord-003614-63rzzos3	351	14	positive	positive	JJ
cord-003614-63rzzos3	351	15	and	and	CC
cord-003614-63rzzos3	351	16	negative	negative	JJ
cord-003614-63rzzos3	351	17	transcriptional	transcriptional	JJ
cord-003614-63rzzos3	351	18	control	control	NN
cord-003614-63rzzos3	351	19	Transcriptional	Transcriptional	NNP
cord-003614-63rzzos3	351	20	responses	response	NNS
cord-003614-63rzzos3	351	21	to	to	IN
cord-003614-63rzzos3	351	22	polypeptide	polypeptide	NN
cord-003614-63rzzos3	351	23	ligands	ligand	NNS
cord-003614-63rzzos3	351	24	:	:	:
cord-003614-63rzzos3	352	1	The	the	DT
cord-003614-63rzzos3	352	2	JAK	JAK	NNP
cord-003614-63rzzos3	352	3	-	-	HYPH
cord-003614-63rzzos3	352	4	STAT	stat	NN
cord-003614-63rzzos3	352	5	pathway	pathway	NN
cord-003614-63rzzos3	352	6	Identification	identification	NN
cord-003614-63rzzos3	352	7	of	of	IN
cord-003614-63rzzos3	352	8	new	new	JJ
cord-003614-63rzzos3	352	9	type	type	NN
cord-003614-63rzzos3	353	1	I	-PRON-	PRP
cord-003614-63rzzos3	353	2	interferon	interferon	NN
cord-003614-63rzzos3	353	3	-	-	HYPH
cord-003614-63rzzos3	353	4	stimulated	stimulate	VBN
cord-003614-63rzzos3	353	5	genes	gene	NNS
cord-003614-63rzzos3	353	6	and	and	CC
cord-003614-63rzzos3	353	7	investigation	investigation	NN
cord-003614-63rzzos3	353	8	of	of	IN
cord-003614-63rzzos3	353	9	their	-PRON-	PRP$
cord-003614-63rzzos3	353	10	involvement	involvement	NN
cord-003614-63rzzos3	353	11	in	in	IN
cord-003614-63rzzos3	353	12	IFN	IFN	NNP
cord-003614-63rzzos3	353	13	-	-	HYPH
cord-003614-63rzzos3	353	14	beta	beta	NN
cord-003614-63rzzos3	353	15	activation	activation	NN
cord-003614-63rzzos3	353	16	Interferon	Interferon	NNP
cord-003614-63rzzos3	353	17	regulated	regulate	VBD
cord-003614-63rzzos3	353	18	gene	gene	NN
cord-003614-63rzzos3	353	19	(	(	-LRB-
cord-003614-63rzzos3	353	20	IRG	IRG	NNP
cord-003614-63rzzos3	353	21	)	)	-RRB-
cord-003614-63rzzos3	353	22	expression	expression	NN
cord-003614-63rzzos3	353	23	-	-	HYPH
cord-003614-63rzzos3	353	24	signature	signature	NN
cord-003614-63rzzos3	353	25	in	in	IN
cord-003614-63rzzos3	353	26	a	a	DT
cord-003614-63rzzos3	353	27	mouse	mouse	NN
cord-003614-63rzzos3	353	28	model	model	NN
cord-003614-63rzzos3	353	29	of	of	IN
cord-003614-63rzzos3	353	30	chikungunya	chikungunya	NN
cord-003614-63rzzos3	353	31	virus	virus	NN
cord-003614-63rzzos3	353	32	neurovirulence	neurovirulence	NNP
cord-003614-63rzzos3	353	33	Canonical	canonical	JJ
cord-003614-63rzzos3	353	34	and	and	CC
cord-003614-63rzzos3	353	35	Non	non	JJ
cord-003614-63rzzos3	353	36	-	-	JJ
cord-003614-63rzzos3	353	37	Canonical	canonical	JJ
cord-003614-63rzzos3	353	38	Aspects	aspect	NNS
cord-003614-63rzzos3	353	39	of	of	IN
cord-003614-63rzzos3	353	40	JAK	JAK	NNP
cord-003614-63rzzos3	353	41	-	-	HYPH
cord-003614-63rzzos3	353	42	STAT	STAT	NNP
cord-003614-63rzzos3	353	43	Signaling	signaling	NN
cord-003614-63rzzos3	353	44	:	:	:
cord-003614-63rzzos3	354	1	Lessons	lesson	NNS
cord-003614-63rzzos3	354	2	from	from	IN
cord-003614-63rzzos3	354	3	Interferons	Interferons	NNPS
cord-003614-63rzzos3	354	4	for	for	IN
cord-003614-63rzzos3	354	5	Cytokine	cytokine	NN
cord-003614-63rzzos3	354	6	Responses	response	NNS
cord-003614-63rzzos3	354	7	STAT2	STAT2	NNS
cord-003614-63rzzos3	354	8	mediates	mediate	VBZ
cord-003614-63rzzos3	354	9	innate	innate	JJ
cord-003614-63rzzos3	354	10	immunity	immunity	NN
cord-003614-63rzzos3	354	11	to	to	IN
cord-003614-63rzzos3	354	12	Dengue	dengue	NN
cord-003614-63rzzos3	354	13	virus	virus	NN
cord-003614-63rzzos3	354	14	in	in	IN
cord-003614-63rzzos3	354	15	the	the	DT
cord-003614-63rzzos3	354	16	absence	absence	NN
cord-003614-63rzzos3	354	17	of	of	IN
cord-003614-63rzzos3	354	18	STAT1	stat1	NN
cord-003614-63rzzos3	354	19	via	via	IN
cord-003614-63rzzos3	354	20	the	the	DT
cord-003614-63rzzos3	354	21	type	type	NN
cord-003614-63rzzos3	355	1	I	-PRON-	PRP
cord-003614-63rzzos3	355	2	interferon	interferon	VBD
cord-003614-63rzzos3	355	3	receptor	receptor	NN
cord-003614-63rzzos3	356	1	In	in	IN
cord-003614-63rzzos3	356	2	vitro	vitro	FW
cord-003614-63rzzos3	356	3	and	and	CC
cord-003614-63rzzos3	356	4	in	in	IN
cord-003614-63rzzos3	356	5	vivo	vivo	NN
cord-003614-63rzzos3	356	6	properties	property	NNS
cord-003614-63rzzos3	356	7	of	of	IN
cord-003614-63rzzos3	356	8	the	the	DT
cord-003614-63rzzos3	356	9	virus	virus	NN
cord-003614-63rzzos3	356	10	causing	cause	VBG
cord-003614-63rzzos3	356	11	natural	natural	JJ
cord-003614-63rzzos3	356	12	canine	canine	JJ
cord-003614-63rzzos3	356	13	distemper	distemper	NN
cord-003614-63rzzos3	356	14	encephalitis	encephalitis	NN
cord-003614-63rzzos3	356	15	Interferon	Interferon	NNP
cord-003614-63rzzos3	356	16	in	in	IN
cord-003614-63rzzos3	356	17	cerebrospinal	cerebrospinal	JJ
cord-003614-63rzzos3	356	18	fluid	fluid	NN
cord-003614-63rzzos3	356	19	.	.	.
cord-003614-63rzzos3	357	1	A	a	DT
cord-003614-63rzzos3	357	2	marker	marker	NN
cord-003614-63rzzos3	357	3	for	for	IN
cord-003614-63rzzos3	357	4	viral	viral	JJ
cord-003614-63rzzos3	357	5	persistence	persistence	NN
cord-003614-63rzzos3	357	6	of	of	IN
cord-003614-63rzzos3	357	7	canine	canine	JJ
cord-003614-63rzzos3	357	8	distemper	distemper	NN
cord-003614-63rzzos3	357	9	encephalomyelitis	encephalomyelitis	NN
cord-003614-63rzzos3	357	10	Immunohistochemical	Immunohistochemical	NNP
cord-003614-63rzzos3	357	11	evaluation	evaluation	NN
cord-003614-63rzzos3	357	12	of	of	IN
cord-003614-63rzzos3	357	13	mx	mx	NNP
cord-003614-63rzzos3	357	14	protein	protein	NN
cord-003614-63rzzos3	357	15	expression	expression	NN
cord-003614-63rzzos3	357	16	in	in	IN
cord-003614-63rzzos3	357	17	canine	canine	JJ
cord-003614-63rzzos3	357	18	encephalitides	encephalitis	NNS
cord-003614-63rzzos3	358	1	Morbillivirus	Morbillivirus	NNP
cord-003614-63rzzos3	358	2	control	control	NN
cord-003614-63rzzos3	358	3	of	of	IN
cord-003614-63rzzos3	358	4	the	the	DT
cord-003614-63rzzos3	358	5	interferon	interferon	NN
cord-003614-63rzzos3	358	6	response	response	NN
cord-003614-63rzzos3	358	7	:	:	:
cord-003614-63rzzos3	358	8	Relevance	relevance	NN
cord-003614-63rzzos3	358	9	of	of	IN
cord-003614-63rzzos3	358	10	STAT2	STAT2	NNS
cord-003614-63rzzos3	358	11	and	and	CC
cord-003614-63rzzos3	358	12	mda5	mda5	NNS
cord-003614-63rzzos3	358	13	but	but	CC
cord-003614-63rzzos3	358	14	not	not	RB
cord-003614-63rzzos3	358	15	STAT1	stat1	VB
cord-003614-63rzzos3	358	16	for	for	IN
cord-003614-63rzzos3	358	17	canine	canine	JJ
cord-003614-63rzzos3	358	18	distemper	distemper	NN
cord-003614-63rzzos3	358	19	virus	virus	NN
cord-003614-63rzzos3	358	20	virulence	virulence	NN
cord-003614-63rzzos3	358	21	in	in	IN
cord-003614-63rzzos3	358	22	ferrets	ferret	NNS
cord-003614-63rzzos3	358	23	High	high	JJ
cord-003614-63rzzos3	358	24	level	level	NN
cord-003614-63rzzos3	358	25	activity	activity	NN
cord-003614-63rzzos3	358	26	of	of	IN
cord-003614-63rzzos3	358	27	2	2	CD
cord-003614-63rzzos3	358	28	'	'	''
cord-003614-63rzzos3	358	29	,	,	.
cord-003614-63rzzos3	359	1	5'-oligoadenylate	5'-oligoadenylate	CD
cord-003614-63rzzos3	359	2	synthetase	synthetase	NNP
cord-003614-63rzzos3	359	3	in	in	IN
cord-003614-63rzzos3	359	4	dog	dog	NN
cord-003614-63rzzos3	359	5	serum	serum	NN
cord-003614-63rzzos3	359	6	Transcriptional	Transcriptional	NNP
cord-003614-63rzzos3	359	7	changes	change	NNS
cord-003614-63rzzos3	359	8	in	in	IN
cord-003614-63rzzos3	359	9	canine	canine	JJ
cord-003614-63rzzos3	359	10	distemper	distemper	NN
cord-003614-63rzzos3	359	11	virus	virus	NN
cord-003614-63rzzos3	359	12	-	-	HYPH
cord-003614-63rzzos3	359	13	induced	induce	VBN
cord-003614-63rzzos3	359	14	demyelinating	demyelinate	VBG
cord-003614-63rzzos3	359	15	leukoencephalitis	leukoencephalitis	NNP
cord-003614-63rzzos3	359	16	favor	favor	VBP
cord-003614-63rzzos3	359	17	a	a	DT
cord-003614-63rzzos3	359	18	biphasic	biphasic	JJ
cord-003614-63rzzos3	359	19	mode	mode	NN
cord-003614-63rzzos3	359	20	of	of	IN
cord-003614-63rzzos3	359	21	demyelination	demyelination	NN
cord-003614-63rzzos3	359	22	Fluorescence	Fluorescence	NNP
cord-003614-63rzzos3	359	23	-	-	HYPH
cord-003614-63rzzos3	359	24	Activated	activate	VBN
cord-003614-63rzzos3	359	25	Cell	cell	NN
cord-003614-63rzzos3	359	26	Sorting	sorting	NN
cord-003614-63rzzos3	359	27	-	-	HYPH
cord-003614-63rzzos3	359	28	Based	base	VBN
cord-003614-63rzzos3	359	29	Analysis	Analysis	NNP
cord-003614-63rzzos3	360	1	Reveals	reveal	VBZ
cord-003614-63rzzos3	360	2	an	an	DT
cord-003614-63rzzos3	360	3	Asymmetric	Asymmetric	NNP
cord-003614-63rzzos3	360	4	Induction	Induction	NNP
cord-003614-63rzzos3	360	5	of	of	IN
cord-003614-63rzzos3	360	6	Interferon	Interferon	NNP
cord-003614-63rzzos3	360	7	-	-	HYPH
cord-003614-63rzzos3	360	8	Stimulated	stimulate	VBN
cord-003614-63rzzos3	360	9	Genes	Genes	NNPS
cord-003614-63rzzos3	360	10	in	in	IN
cord-003614-63rzzos3	360	11	Response	response	NN
cord-003614-63rzzos3	360	12	to	to	IN
cord-003614-63rzzos3	360	13	Seasonal	Seasonal	NNP
cord-003614-63rzzos3	360	14	Influenza	Influenza	NNP
cord-003614-63rzzos3	360	15	A	A	NNP
cord-003614-63rzzos3	361	1	Virus	Virus	NNP
cord-003614-63rzzos3	361	2	Myxovirus	Myxovirus	NNP
cord-003614-63rzzos3	361	3	resistance	resistance	NN
cord-003614-63rzzos3	361	4	protein	protein	NN
cord-003614-63rzzos3	361	5	A	A	NNP
cord-003614-63rzzos3	361	6	inhibits	inhibit	VBZ
cord-003614-63rzzos3	361	7	hepatitis	hepatitis	NN
cord-003614-63rzzos3	361	8	C	c	NN
cord-003614-63rzzos3	361	9	virus	virus	NN
cord-003614-63rzzos3	361	10	replication	replication	NN
cord-003614-63rzzos3	361	11	through	through	IN
cord-003614-63rzzos3	361	12	JAK	JAK	NNP
cord-003614-63rzzos3	361	13	-	-	HYPH
cord-003614-63rzzos3	361	14	STAT	STAT	NNP
cord-003614-63rzzos3	361	15	pathway	pathway	NN
cord-003614-63rzzos3	361	16	activation	activation	NN
cord-003614-63rzzos3	361	17	Differential	Differential	NNP
cord-003614-63rzzos3	361	18	Expression	expression	NN
cord-003614-63rzzos3	361	19	of	of	IN
cord-003614-63rzzos3	361	20	Genes	Genes	NNP
cord-003614-63rzzos3	361	21	Related	relate	VBN
cord-003614-63rzzos3	361	22	to	to	IN
cord-003614-63rzzos3	361	23	Innate	Innate	NNP
cord-003614-63rzzos3	361	24	Immune	Immune	NNP
cord-003614-63rzzos3	361	25	Responses	response	NNS
cord-003614-63rzzos3	361	26	in	in	IN
cord-003614-63rzzos3	361	27	Ex	Ex	NNP
cord-003614-63rzzos3	361	28	Vivo	Vivo	NNP
cord-003614-63rzzos3	361	29	Spinal	Spinal	NNP
cord-003614-63rzzos3	361	30	Cord	Cord	NNP
cord-003614-63rzzos3	361	31	and	and	CC
cord-003614-63rzzos3	361	32	Cerebellar	Cerebellar	NNP
cord-003614-63rzzos3	361	33	Slice	slice	NN
cord-003614-63rzzos3	361	34	Cultures	culture	NNS
cord-003614-63rzzos3	361	35	Infected	infect	VBN
cord-003614-63rzzos3	361	36	with	with	IN
cord-003614-63rzzos3	361	37	West	West	NNP
cord-003614-63rzzos3	361	38	Nile	Nile	NNP
cord-003614-63rzzos3	361	39	Virus	Virus	NNP
cord-003614-63rzzos3	362	1	Interferon	interferon	NN
cord-003614-63rzzos3	362	2	-	-	HYPH
cord-003614-63rzzos3	362	3	stimulated	stimulate	VBN
cord-003614-63rzzos3	362	4	gene	gene	NN
cord-003614-63rzzos3	362	5	15	15	CD
cord-003614-63rzzos3	363	1	(	(	-LRB-
cord-003614-63rzzos3	363	2	ISG15	ISG15	NNP
cord-003614-63rzzos3	363	3	)	)	-RRB-
cord-003614-63rzzos3	363	4	conjugates	conjugate	VBZ
cord-003614-63rzzos3	363	5	proteins	protein	NNS
cord-003614-63rzzos3	363	6	in	in	IN
cord-003614-63rzzos3	363	7	dermatomyositis	dermatomyositis	NN
cord-003614-63rzzos3	363	8	muscle	muscle	NN
cord-003614-63rzzos3	363	9	with	with	IN
cord-003614-63rzzos3	364	1	perifascicular	perifascicular	JJ
cord-003614-63rzzos3	364	2	atrophy	atrophy	NN
cord-003614-63rzzos3	364	3	Hepatitis	Hepatitis	NNP
cord-003614-63rzzos3	364	4	C	C	NNP
cord-003614-63rzzos3	364	5	virus	virus	NN
cord-003614-63rzzos3	364	6	induces	induce	VBZ
cord-003614-63rzzos3	364	7	interferon	interferon	NN
cord-003614-63rzzos3	364	8	-	-	HYPH
cord-003614-63rzzos3	364	9	lambda	lambda	NN
cord-003614-63rzzos3	364	10	and	and	CC
cord-003614-63rzzos3	364	11	interferon	interferon	NN
cord-003614-63rzzos3	364	12	-	-	HYPH
cord-003614-63rzzos3	364	13	stimulated	stimulate	VBN
cord-003614-63rzzos3	364	14	genes	gene	NNS
cord-003614-63rzzos3	364	15	in	in	IN
cord-003614-63rzzos3	364	16	primary	primary	JJ
cord-003614-63rzzos3	364	17	liver	liver	NN
cord-003614-63rzzos3	364	18	cultures	culture	NNS
cord-003614-63rzzos3	364	19	Type	type	NN
cord-003614-63rzzos3	364	20	I	-PRON-	PRP
cord-003614-63rzzos3	364	21	interferon	interferon	NN
cord-003614-63rzzos3	364	22	[	[	-LRB-
cord-003614-63rzzos3	364	23	corrected	correct	VBD
cord-003614-63rzzos3	364	24	]	]	-RRB-
cord-003614-63rzzos3	364	25	gene	gene	NN
cord-003614-63rzzos3	364	26	induction	induction	NN
cord-003614-63rzzos3	364	27	by	by	IN
cord-003614-63rzzos3	364	28	the	the	DT
cord-003614-63rzzos3	364	29	interferon	interferon	NN
cord-003614-63rzzos3	364	30	regulatory	regulatory	JJ
cord-003614-63rzzos3	364	31	factor	factor	NN
cord-003614-63rzzos3	364	32	family	family	NN
cord-003614-63rzzos3	364	33	of	of	IN
cord-003614-63rzzos3	364	34	transcription	transcription	NN
cord-003614-63rzzos3	364	35	factors	factor	NNS
cord-003614-63rzzos3	365	1	Interferon	interferon	NN
cord-003614-63rzzos3	365	2	regulatory	regulatory	JJ
cord-003614-63rzzos3	365	3	factor	factor	NN
cord-003614-63rzzos3	365	4	3	3	CD
cord-003614-63rzzos3	365	5	in	in	IN
cord-003614-63rzzos3	365	6	adaptive	adaptive	JJ
cord-003614-63rzzos3	365	7	immune	immune	JJ
cord-003614-63rzzos3	365	8	responses	response	NNS
cord-003614-63rzzos3	365	9	IRF	IRF	NNP
cord-003614-63rzzos3	365	10	family	family	NN
cord-003614-63rzzos3	365	11	of	of	IN
cord-003614-63rzzos3	365	12	transcription	transcription	NN
cord-003614-63rzzos3	365	13	factors	factor	NNS
cord-003614-63rzzos3	365	14	as	as	IN
cord-003614-63rzzos3	365	15	regulators	regulator	NNS
cord-003614-63rzzos3	365	16	of	of	IN
cord-003614-63rzzos3	365	17	host	host	NN
cord-003614-63rzzos3	365	18	defense	defense	NN
cord-003614-63rzzos3	366	1	The	the	DT
cord-003614-63rzzos3	366	2	IRF	IRF	NNP
cord-003614-63rzzos3	366	3	family	family	NN
cord-003614-63rzzos3	366	4	transcription	transcription	NN
cord-003614-63rzzos3	366	5	factors	factor	NNS
cord-003614-63rzzos3	366	6	at	at	IN
cord-003614-63rzzos3	366	7	the	the	DT
cord-003614-63rzzos3	366	8	interface	interface	NN
cord-003614-63rzzos3	366	9	of	of	IN
cord-003614-63rzzos3	366	10	innate	innate	JJ
cord-003614-63rzzos3	366	11	and	and	CC
cord-003614-63rzzos3	366	12	adaptive	adaptive	JJ
cord-003614-63rzzos3	366	13	immune	immune	JJ
cord-003614-63rzzos3	366	14	responses	response	NNS
cord-003614-63rzzos3	367	1	OASL1	OASL1	NNP
cord-003614-63rzzos3	367	2	inhibits	inhibit	VBZ
cord-003614-63rzzos3	367	3	translation	translation	NN
cord-003614-63rzzos3	367	4	of	of	IN
cord-003614-63rzzos3	367	5	the	the	DT
cord-003614-63rzzos3	367	6	type	type	NN
cord-003614-63rzzos3	368	1	I	-PRON-	PRP
cord-003614-63rzzos3	368	2	interferon	interferon	NN
cord-003614-63rzzos3	368	3	-	-	HYPH
cord-003614-63rzzos3	368	4	regulating	regulate	VBG
cord-003614-63rzzos3	368	5	transcription	transcription	NN
cord-003614-63rzzos3	368	6	factor	factor	NN
cord-003614-63rzzos3	369	1	IRF7	IRF7	NNP
cord-003614-63rzzos3	369	2	Negative	negative	JJ
cord-003614-63rzzos3	369	3	regulation	regulation	NN
cord-003614-63rzzos3	369	4	of	of	IN
cord-003614-63rzzos3	369	5	type	type	NN
cord-003614-63rzzos3	370	1	I	-PRON-	PRP
cord-003614-63rzzos3	370	2	IFN	IFN	NNP
cord-003614-63rzzos3	370	3	expression	expression	NN
cord-003614-63rzzos3	370	4	by	by	IN
cord-003614-63rzzos3	370	5	OASL1	OASL1	NNP
cord-003614-63rzzos3	370	6	permits	permit	VBZ
cord-003614-63rzzos3	370	7	chronic	chronic	JJ
cord-003614-63rzzos3	370	8	viral	viral	JJ
cord-003614-63rzzos3	370	9	infection	infection	NN
cord-003614-63rzzos3	370	10	and	and	CC
cord-003614-63rzzos3	370	11	CD8(+	cd8(+	CD
cord-003614-63rzzos3	370	12	)	)	-RRB-
cord-003614-63rzzos3	370	13	T	t	NN
cord-003614-63rzzos3	370	14	-	-	HYPH
cord-003614-63rzzos3	370	15	cell	cell	NN
cord-003614-63rzzos3	370	16	exhaustion	exhaustion	NN
cord-003614-63rzzos3	370	17	Master	Master	NNP
cord-003614-63rzzos3	370	18	regulators	regulator	NNS
cord-003614-63rzzos3	370	19	of	of	IN
cord-003614-63rzzos3	370	20	signalling	signal	VBG
cord-003614-63rzzos3	370	21	by	by	IN
cord-003614-63rzzos3	370	22	Toll	toll	NN
cord-003614-63rzzos3	370	23	-	-	HYPH
cord-003614-63rzzos3	370	24	like	like	JJ
cord-003614-63rzzos3	370	25	receptors	receptor	NNS
cord-003614-63rzzos3	370	26	and	and	CC
cord-003614-63rzzos3	370	27	cytosolic	cytosolic	JJ
cord-003614-63rzzos3	370	28	pattern	pattern	NN
cord-003614-63rzzos3	370	29	-	-	HYPH
cord-003614-63rzzos3	370	30	recognition	recognition	NN
cord-003614-63rzzos3	370	31	receptors	receptor	NNS
cord-003614-63rzzos3	371	1	Structural	structural	JJ
cord-003614-63rzzos3	371	2	insights	insight	NNS
cord-003614-63rzzos3	371	3	into	into	IN
cord-003614-63rzzos3	371	4	interferon	interferon	NN
cord-003614-63rzzos3	371	5	regulatory	regulatory	JJ
cord-003614-63rzzos3	371	6	factor	factor	NN
cord-003614-63rzzos3	371	7	activation	activation	NN
cord-003614-63rzzos3	371	8	Differential	differential	JJ
cord-003614-63rzzos3	371	9	viral	viral	JJ
cord-003614-63rzzos3	371	10	induction	induction	NN
cord-003614-63rzzos3	371	11	of	of	IN
cord-003614-63rzzos3	371	12	distinct	distinct	JJ
cord-003614-63rzzos3	371	13	interferon	interferon	NN
cord-003614-63rzzos3	371	14	-	-	HYPH
cord-003614-63rzzos3	371	15	alpha	alpha	NN
cord-003614-63rzzos3	371	16	genes	gene	NNS
cord-003614-63rzzos3	371	17	by	by	IN
cord-003614-63rzzos3	371	18	positive	positive	JJ
cord-003614-63rzzos3	371	19	feedback	feedback	NN
cord-003614-63rzzos3	371	20	through	through	IN
cord-003614-63rzzos3	371	21	interferon	interferon	NN
cord-003614-63rzzos3	371	22	regulatory	regulatory	JJ
cord-003614-63rzzos3	371	23	factor-7	factor-7	NNS
cord-003614-63rzzos3	372	1	Interferon	interferon	NN
cord-003614-63rzzos3	372	2	-	-	HYPH
cord-003614-63rzzos3	372	3	stimulated	stimulate	VBN
cord-003614-63rzzos3	372	4	genes	gene	NNS
cord-003614-63rzzos3	372	5	-	-	:
cord-003614-63rzzos3	372	6	essential	essential	JJ
cord-003614-63rzzos3	372	7	antiviral	antiviral	JJ
cord-003614-63rzzos3	372	8	effectors	effector	NNS
cord-003614-63rzzos3	372	9	implicated	implicate	VBN
cord-003614-63rzzos3	372	10	in	in	IN
cord-003614-63rzzos3	372	11	resistance	resistance	NN
cord-003614-63rzzos3	372	12	to	to	IN
cord-003614-63rzzos3	372	13	Theiler	Theiler	NNP
cord-003614-63rzzos3	372	14	's	's	POS
cord-003614-63rzzos3	372	15	virus	virus	NN
cord-003614-63rzzos3	372	16	-	-	HYPH
cord-003614-63rzzos3	372	17	induced	induce	VBN
cord-003614-63rzzos3	372	18	demyelinating	demyelinate	VBG
cord-003614-63rzzos3	372	19	disease	disease	NN
cord-003614-63rzzos3	372	20	Constitutive	constitutive	JJ
cord-003614-63rzzos3	372	21	expression	expression	NN
cord-003614-63rzzos3	372	22	of	of	IN
cord-003614-63rzzos3	372	23	an	an	DT
cord-003614-63rzzos3	372	24	ISGF2	ISGF2	NNP
cord-003614-63rzzos3	372	25	/	/	SYM
cord-003614-63rzzos3	372	26	IRF1	IRF1	NNP
cord-003614-63rzzos3	372	27	transgene	transgene	NN
cord-003614-63rzzos3	372	28	leads	lead	VBZ
cord-003614-63rzzos3	372	29	to	to	IN
cord-003614-63rzzos3	372	30	interferon	interferon	NN
cord-003614-63rzzos3	372	31	-	-	HYPH
cord-003614-63rzzos3	372	32	independent	independent	JJ
cord-003614-63rzzos3	372	33	activation	activation	NN
cord-003614-63rzzos3	372	34	of	of	IN
cord-003614-63rzzos3	372	35	interferon	interferon	NN
cord-003614-63rzzos3	372	36	-	-	HYPH
cord-003614-63rzzos3	372	37	inducible	inducible	JJ
cord-003614-63rzzos3	372	38	genes	gene	NNS
cord-003614-63rzzos3	372	39	and	and	CC
cord-003614-63rzzos3	372	40	resistance	resistance	NN
cord-003614-63rzzos3	372	41	to	to	IN
cord-003614-63rzzos3	372	42	virus	virus	NN
cord-003614-63rzzos3	372	43	infection	infection	NN
cord-003614-63rzzos3	372	44	IRF1	IRF1	NNP
cord-003614-63rzzos3	372	45	up	up	RB
cord-003614-63rzzos3	372	46	-	-	HYPH
cord-003614-63rzzos3	372	47	regulates	regulate	VBZ
cord-003614-63rzzos3	372	48	isg15	isg15	NNS
cord-003614-63rzzos3	372	49	gene	gene	NN
cord-003614-63rzzos3	372	50	expression	expression	NN
cord-003614-63rzzos3	372	51	in	in	IN
cord-003614-63rzzos3	372	52	dsRNA	dsrna	JJ
cord-003614-63rzzos3	372	53	stimulation	stimulation	NN
cord-003614-63rzzos3	372	54	or	or	CC
cord-003614-63rzzos3	372	55	CSFV	CSFV	NNP
cord-003614-63rzzos3	372	56	infection	infection	NN
cord-003614-63rzzos3	372	57	by	by	IN
cord-003614-63rzzos3	372	58	targeting	target	VBG
cord-003614-63rzzos3	372	59	nucleotides-487	nucleotides-487	NN
cord-003614-63rzzos3	372	60	to	to	TO
cord-003614-63rzzos3	372	61	-325	-325	VB
cord-003614-63rzzos3	372	62	in	in	IN
cord-003614-63rzzos3	372	63	the	the	DT
cord-003614-63rzzos3	372	64	5	5	CD
cord-003614-63rzzos3	372	65	'	'	POS
cord-003614-63rzzos3	372	66	flanking	flanking	NN
cord-003614-63rzzos3	372	67	region	region	NN
cord-003614-63rzzos3	373	1	The	the	DT
cord-003614-63rzzos3	373	2	canine	canine	JJ
cord-003614-63rzzos3	373	3	MHC	MHC	NNP
cord-003614-63rzzos3	373	4	class	class	NN
cord-003614-63rzzos3	373	5	Ia	Ia	NNP
cord-003614-63rzzos3	373	6	allele	allele	NN
cord-003614-63rzzos3	374	1	DLA-88	DLA-88	NNP
cord-003614-63rzzos3	374	2	*	*	NFP
cord-003614-63rzzos3	374	3	508:01	508:01	CD
cord-003614-63rzzos3	374	4	presents	present	VBZ
cord-003614-63rzzos3	374	5	diverse	diverse	JJ
cord-003614-63rzzos3	374	6	self	self	NN
cord-003614-63rzzos3	374	7	-	-	HYPH
cord-003614-63rzzos3	374	8	and	and	CC
cord-003614-63rzzos3	374	9	canine	canine	JJ
cord-003614-63rzzos3	374	10	distemper	distemper	NN
cord-003614-63rzzos3	374	11	virus	virus	NN
cord-003614-63rzzos3	374	12	-	-	HYPH
cord-003614-63rzzos3	374	13	origin	origin	NN
cord-003614-63rzzos3	374	14	peptides	peptide	NNS
cord-003614-63rzzos3	374	15	of	of	IN
cord-003614-63rzzos3	374	16	varying	vary	VBG
cord-003614-63rzzos3	374	17	length	length	NN
cord-003614-63rzzos3	374	18	that	that	WDT
cord-003614-63rzzos3	374	19	have	have	VBP
cord-003614-63rzzos3	374	20	a	a	DT
cord-003614-63rzzos3	374	21	conserved	conserve	VBN
cord-003614-63rzzos3	374	22	binding	binding	NN
cord-003614-63rzzos3	374	23	motif	motif	NN
cord-003614-63rzzos3	374	24	Polymorphism	polymorphism	NN
cord-003614-63rzzos3	374	25	analysis	analysis	NN
cord-003614-63rzzos3	374	26	of	of	IN
cord-003614-63rzzos3	374	27	four	four	CD
cord-003614-63rzzos3	374	28	canine	canine	JJ
cord-003614-63rzzos3	374	29	MHC	MHC	NNP
cord-003614-63rzzos3	374	30	class	class	NN
cord-003614-63rzzos3	375	1	I	-PRON-	PRP
cord-003614-63rzzos3	375	2	genes	gene	NNS
cord-003614-63rzzos3	376	1	Transcription	transcription	NN
cord-003614-63rzzos3	376	2	factor	factor	NN
cord-003614-63rzzos3	376	3	redundancy	redundancy	NN
cord-003614-63rzzos3	376	4	ensures	ensure	VBZ
cord-003614-63rzzos3	376	5	induction	induction	NN
cord-003614-63rzzos3	376	6	of	of	IN
cord-003614-63rzzos3	376	7	the	the	DT
cord-003614-63rzzos3	376	8	antiviral	antiviral	JJ
cord-003614-63rzzos3	376	9	state	state	NN
cord-003614-63rzzos3	376	10	Viral	Viral	NNP
cord-003614-63rzzos3	376	11	Evasion	Evasion	NNP
cord-003614-63rzzos3	376	12	Strategies	Strategies	NNPS
cord-003614-63rzzos3	376	13	in	in	IN
cord-003614-63rzzos3	376	14	Type	type	NN
cord-003614-63rzzos3	377	1	I	-PRON-	PRP
cord-003614-63rzzos3	377	2	IFN	IFN	NNP
cord-003614-63rzzos3	377	3	Signaling	Signaling	NNP
cord-003614-63rzzos3	377	4	-	-	HYPH
cord-003614-63rzzos3	377	5	A	A	NNP
cord-003614-63rzzos3	377	6	Summary	Summary	NNP
cord-003614-63rzzos3	377	7	of	of	IN
cord-003614-63rzzos3	377	8	Recent	recent	JJ
cord-003614-63rzzos3	377	9	Developments	development	NNS
cord-003614-63rzzos3	378	1	ISGylation	ISGylation	NNP
cord-003614-63rzzos3	378	2	-	-	HYPH
cord-003614-63rzzos3	378	3	A	a	DT
cord-003614-63rzzos3	378	4	key	key	NN
cord-003614-63rzzos3	378	5	to	to	TO
cord-003614-63rzzos3	378	6	lock	lock	VB
cord-003614-63rzzos3	378	7	the	the	DT
cord-003614-63rzzos3	378	8	cell	cell	NN
cord-003614-63rzzos3	378	9	gates	gate	NNS
cord-003614-63rzzos3	378	10	for	for	IN
cord-003614-63rzzos3	378	11	preventing	prevent	VBG
cord-003614-63rzzos3	378	12	the	the	DT
cord-003614-63rzzos3	378	13	spread	spread	NN
cord-003614-63rzzos3	378	14	of	of	IN
cord-003614-63rzzos3	378	15	threats	threat	NNS
cord-003614-63rzzos3	378	16	Beyond	beyond	IN
cord-003614-63rzzos3	378	17	ISGlylation	isglylation	NN
cord-003614-63rzzos3	378	18	:	:	:
cord-003614-63rzzos3	378	19	Functions	function	NNS
cord-003614-63rzzos3	378	20	of	of	IN
cord-003614-63rzzos3	378	21	Free	Free	NNP
cord-003614-63rzzos3	378	22	Intracellular	Intracellular	NNP
cord-003614-63rzzos3	378	23	and	and	CC
cord-003614-63rzzos3	378	24	Extracellular	Extracellular	NNP
cord-003614-63rzzos3	378	25	ISG15	isg15	NN
cord-003614-63rzzos3	379	1	ISG15	isg15	NN
cord-003614-63rzzos3	379	2	:	:	:
cord-003614-63rzzos3	380	1	In	in	IN
cord-003614-63rzzos3	380	2	Sickness	Sickness	NNP
cord-003614-63rzzos3	380	3	and	and	CC
cord-003614-63rzzos3	380	4	in	in	IN
cord-003614-63rzzos3	380	5	Health	Health	NNP
cord-003614-63rzzos3	380	6	Negative	negative	JJ
cord-003614-63rzzos3	380	7	feedback	feedback	NN
cord-003614-63rzzos3	380	8	regulation	regulation	NN
cord-003614-63rzzos3	380	9	of	of	IN
cord-003614-63rzzos3	380	10	RIG	rig	NN
cord-003614-63rzzos3	380	11	-	-	HYPH
cord-003614-63rzzos3	380	12	I	i	NN
cord-003614-63rzzos3	380	13	-	-	HYPH
cord-003614-63rzzos3	380	14	mediated	mediate	VBN
cord-003614-63rzzos3	380	15	antiviral	antiviral	JJ
cord-003614-63rzzos3	380	16	signaling	signal	VBG
cord-003614-63rzzos3	380	17	by	by	IN
cord-003614-63rzzos3	380	18	interferon	interferon	NN
cord-003614-63rzzos3	380	19	-	-	HYPH
cord-003614-63rzzos3	380	20	induced	induce	VBN
cord-003614-63rzzos3	380	21	ISG15	isg15	NN
cord-003614-63rzzos3	380	22	conjugation	conjugation	NN
cord-003614-63rzzos3	380	23	Positive	positive	JJ
cord-003614-63rzzos3	380	24	regulation	regulation	NN
cord-003614-63rzzos3	380	25	of	of	IN
cord-003614-63rzzos3	380	26	interferon	interferon	NN
cord-003614-63rzzos3	380	27	regulatory	regulatory	JJ
cord-003614-63rzzos3	380	28	factor	factor	NN
cord-003614-63rzzos3	380	29	3	3	CD
cord-003614-63rzzos3	380	30	activation	activation	NN
cord-003614-63rzzos3	380	31	by	by	IN
cord-003614-63rzzos3	380	32	Herc5	Herc5	NNP
cord-003614-63rzzos3	381	1	via	via	IN
cord-003614-63rzzos3	381	2	ISG15	ISG15	NNP
cord-003614-63rzzos3	382	1	modification	modification	NN
cord-003614-63rzzos3	382	2	ISG15	ISG15	NNP
cord-003614-63rzzos3	382	3	deficiency	deficiency	NN
cord-003614-63rzzos3	382	4	and	and	CC
cord-003614-63rzzos3	382	5	increased	increase	VBN
cord-003614-63rzzos3	382	6	viral	viral	JJ
cord-003614-63rzzos3	382	7	resistance	resistance	NN
cord-003614-63rzzos3	382	8	in	in	IN
cord-003614-63rzzos3	382	9	humans	human	NNS
cord-003614-63rzzos3	382	10	but	but	CC
cord-003614-63rzzos3	382	11	not	not	RB
cord-003614-63rzzos3	382	12	mice	mouse	NNS
cord-003614-63rzzos3	382	13	Mycobacterial	Mycobacterial	NNP
cord-003614-63rzzos3	382	14	disease	disease	NN
cord-003614-63rzzos3	382	15	and	and	CC
cord-003614-63rzzos3	382	16	impaired	impair	VBD
cord-003614-63rzzos3	382	17	IFN	IFN	NNP
cord-003614-63rzzos3	382	18	-	-	HYPH
cord-003614-63rzzos3	382	19	gamma	gamma	NN
cord-003614-63rzzos3	382	20	immunity	immunity	NN
cord-003614-63rzzos3	382	21	in	in	IN
cord-003614-63rzzos3	382	22	humans	human	NNS
cord-003614-63rzzos3	382	23	with	with	IN
cord-003614-63rzzos3	382	24	inherited	inherit	VBN
cord-003614-63rzzos3	382	25	ISG15	ISG15	NNP
cord-003614-63rzzos3	382	26	deficiency	deficiency	NN
cord-003614-63rzzos3	383	1	A	a	DT
cord-003614-63rzzos3	383	2	human	human	JJ
cord-003614-63rzzos3	383	3	15-kDa	15-kda	CD
cord-003614-63rzzos3	384	1	IFN	IFN	NNP
cord-003614-63rzzos3	384	2	-	-	HYPH
cord-003614-63rzzos3	384	3	induced	induce	VBN
cord-003614-63rzzos3	384	4	protein	protein	NN
cord-003614-63rzzos3	384	5	induces	induce	VBZ
cord-003614-63rzzos3	384	6	the	the	DT
cord-003614-63rzzos3	384	7	secretion	secretion	NN
cord-003614-63rzzos3	384	8	of	of	IN
cord-003614-63rzzos3	384	9	IFN	IFN	NNP
cord-003614-63rzzos3	384	10	-	-	HYPH
cord-003614-63rzzos3	384	11	gamma	gamma	NNP
cord-003614-63rzzos3	384	12	Identification	identification	NN
cord-003614-63rzzos3	384	13	and	and	CC
cord-003614-63rzzos3	384	14	function	function	VB
cord-003614-63rzzos3	384	15	analysis	analysis	NN
cord-003614-63rzzos3	384	16	of	of	IN
cord-003614-63rzzos3	384	17	canine	canine	JJ
cord-003614-63rzzos3	384	18	stimulator	stimulator	NN
cord-003614-63rzzos3	384	19	of	of	IN
cord-003614-63rzzos3	384	20	interferon	interferon	NN
cord-003614-63rzzos3	384	21	gene	gene	NN
cord-003614-63rzzos3	384	22	(	(	-LRB-
cord-003614-63rzzos3	384	23	STING	sting	NN
cord-003614-63rzzos3	384	24	)	)	-RRB-
cord-003614-63rzzos3	384	25	Increase	increase	NN
cord-003614-63rzzos3	384	26	of	of	IN
cord-003614-63rzzos3	384	27	pro	pro	JJ
cord-003614-63rzzos3	384	28	-	-	JJ
cord-003614-63rzzos3	384	29	inflammatory	inflammatory	JJ
cord-003614-63rzzos3	384	30	cytokine	cytokine	NN
cord-003614-63rzzos3	384	31	expression	expression	NN
cord-003614-63rzzos3	384	32	in	in	IN
cord-003614-63rzzos3	384	33	non	non	JJ
cord-003614-63rzzos3	384	34	-	-	JJ
cord-003614-63rzzos3	384	35	demyelinating	demyelinating	JJ
cord-003614-63rzzos3	384	36	early	early	JJ
cord-003614-63rzzos3	384	37	cerebral	cerebral	JJ
cord-003614-63rzzos3	384	38	lesions	lesion	NNS
cord-003614-63rzzos3	384	39	in	in	IN
cord-003614-63rzzos3	384	40	nervous	nervous	JJ
cord-003614-63rzzos3	384	41	canine	canine	JJ
cord-003614-63rzzos3	384	42	distemper	distemper	NN
cord-003614-63rzzos3	384	43	Dominating	dominate	VBG
cord-003614-63rzzos3	384	44	interleukin-10	interleukin-10	FW
cord-003614-63rzzos3	384	45	mRNA	mrna	NN
cord-003614-63rzzos3	384	46	expression	expression	NN
cord-003614-63rzzos3	384	47	induction	induction	NN
cord-003614-63rzzos3	384	48	in	in	IN
cord-003614-63rzzos3	384	49	cerebrospinal	cerebrospinal	JJ
cord-003614-63rzzos3	384	50	fluid	fluid	JJ
cord-003614-63rzzos3	384	51	cells	cell	NNS
cord-003614-63rzzos3	384	52	of	of	IN
cord-003614-63rzzos3	384	53	dogs	dog	NNS
cord-003614-63rzzos3	384	54	with	with	IN
cord-003614-63rzzos3	384	55	natural	natural	JJ
cord-003614-63rzzos3	384	56	canine	canine	JJ
cord-003614-63rzzos3	384	57	distemper	distemper	NN
cord-003614-63rzzos3	384	58	virus	virus	NN
cord-003614-63rzzos3	384	59	induced	induce	VBN
cord-003614-63rzzos3	384	60	demyelinating	demyelinate	VBG
cord-003614-63rzzos3	384	61	and	and	CC
cord-003614-63rzzos3	384	62	non	non	JJ
cord-003614-63rzzos3	384	63	-	-	JJ
cord-003614-63rzzos3	384	64	demyelinating	demyelinating	JJ
cord-003614-63rzzos3	384	65	CNS	CNS	NNP
cord-003614-63rzzos3	384	66	lesions	lesion	NNS
cord-003614-63rzzos3	384	67	Increased	increase	VBD
cord-003614-63rzzos3	384	68	expression	expression	NN
cord-003614-63rzzos3	384	69	of	of	IN
cord-003614-63rzzos3	384	70	pro	pro	JJ
cord-003614-63rzzos3	384	71	-	-	JJ
cord-003614-63rzzos3	384	72	inflammatory	inflammatory	JJ
cord-003614-63rzzos3	384	73	cytokines	cytokine	NNS
cord-003614-63rzzos3	384	74	and	and	CC
cord-003614-63rzzos3	384	75	lack	lack	NN
cord-003614-63rzzos3	384	76	of	of	IN
cord-003614-63rzzos3	384	77	up	up	NN
cord-003614-63rzzos3	384	78	-	-	HYPH
cord-003614-63rzzos3	384	79	regulation	regulation	NN
cord-003614-63rzzos3	384	80	of	of	IN
cord-003614-63rzzos3	384	81	anti	anti	JJ
cord-003614-63rzzos3	384	82	-	-	JJ
cord-003614-63rzzos3	384	83	inflammatory	inflammatory	JJ
cord-003614-63rzzos3	384	84	cytokines	cytokine	NNS
cord-003614-63rzzos3	384	85	in	in	IN
cord-003614-63rzzos3	384	86	early	early	JJ
cord-003614-63rzzos3	384	87	distemper	distemper	NN
cord-003614-63rzzos3	384	88	CNS	CNS	NNP
cord-003614-63rzzos3	384	89	lesions	lesion	NNS
cord-003614-63rzzos3	384	90	Protein	Protein	NNP
cord-003614-63rzzos3	384	91	kinase	kinase	VBZ
cord-003614-63rzzos3	384	92	PKR	PKR	NNP
cord-003614-63rzzos3	384	93	and	and	CC
cord-003614-63rzzos3	384	94	RNA	RNA	NNP
cord-003614-63rzzos3	385	1	adenosine	adenosine	NN
cord-003614-63rzzos3	385	2	deaminase	deaminase	NNP
cord-003614-63rzzos3	386	1	ADAR1	ADAR1	NNP
cord-003614-63rzzos3	386	2	:	:	:
cord-003614-63rzzos3	387	1	New	new	JJ
cord-003614-63rzzos3	387	2	roles	role	NNS
cord-003614-63rzzos3	387	3	for	for	IN
cord-003614-63rzzos3	387	4	old	old	JJ
cord-003614-63rzzos3	387	5	players	player	NNS
cord-003614-63rzzos3	387	6	as	as	IN
cord-003614-63rzzos3	387	7	modulators	modulator	NNS
cord-003614-63rzzos3	387	8	of	of	IN
cord-003614-63rzzos3	387	9	the	the	DT
cord-003614-63rzzos3	387	10	interferon	interferon	NN
cord-003614-63rzzos3	387	11	response	response	NN
cord-003614-63rzzos3	388	1	The	the	DT
cord-003614-63rzzos3	388	2	impact	impact	NN
cord-003614-63rzzos3	388	3	of	of	IN
cord-003614-63rzzos3	388	4	PKR	PKR	NNP
cord-003614-63rzzos3	388	5	activation	activation	NN
cord-003614-63rzzos3	388	6	:	:	:
cord-003614-63rzzos3	388	7	From	from	IN
cord-003614-63rzzos3	388	8	neurodegeneration	neurodegeneration	NN
cord-003614-63rzzos3	388	9	to	to	IN
cord-003614-63rzzos3	388	10	cancer	cancer	NN
cord-003614-63rzzos3	388	11	Activation	activation	NN
cord-003614-63rzzos3	388	12	of	of	IN
cord-003614-63rzzos3	388	13	double	double	RB
cord-003614-63rzzos3	388	14	-	-	HYPH
cord-003614-63rzzos3	388	15	stranded	strand	VBN
cord-003614-63rzzos3	388	16	RNA	RNA	NNP
cord-003614-63rzzos3	388	17	-	-	HYPH
cord-003614-63rzzos3	388	18	activated	activate	VBN
cord-003614-63rzzos3	388	19	protein	protein	NN
cord-003614-63rzzos3	388	20	kinase	kinase	NN
cord-003614-63rzzos3	388	21	(	(	-LRB-
cord-003614-63rzzos3	388	22	PKR	PKR	NNP
cord-003614-63rzzos3	388	23	)	)	-RRB-
cord-003614-63rzzos3	388	24	by	by	IN
cord-003614-63rzzos3	388	25	interferon	interferon	NN
cord-003614-63rzzos3	388	26	-	-	HYPH
cord-003614-63rzzos3	388	27	stimulated	stimulate	VBN
cord-003614-63rzzos3	388	28	gene	gene	NN
cord-003614-63rzzos3	388	29	15	15	CD
cord-003614-63rzzos3	389	1	(	(	-LRB-
cord-003614-63rzzos3	389	2	ISG15	isg15	NN
cord-003614-63rzzos3	389	3	)	)	-RRB-
cord-003614-63rzzos3	389	4	modification	modification	NN
cord-003614-63rzzos3	389	5	down	down	RB
cord-003614-63rzzos3	389	6	-	-	HYPH
cord-003614-63rzzos3	389	7	regulates	regulate	VBZ
cord-003614-63rzzos3	389	8	protein	protein	NN
cord-003614-63rzzos3	389	9	translation	translation	NN
cord-003614-63rzzos3	390	1	The	the	DT
cord-003614-63rzzos3	390	2	double	double	RB
cord-003614-63rzzos3	390	3	-	-	HYPH
cord-003614-63rzzos3	390	4	stranded	strand	VBN
cord-003614-63rzzos3	390	5	RNA	rna	NN
cord-003614-63rzzos3	390	6	-	-	HYPH
cord-003614-63rzzos3	390	7	dependent	dependent	JJ
cord-003614-63rzzos3	390	8	protein	protein	NN
cord-003614-63rzzos3	390	9	kinase	kinase	VBZ
cord-003614-63rzzos3	390	10	PKR	PKR	NNP
cord-003614-63rzzos3	390	11	:	:	:
cord-003614-63rzzos3	391	1	Structure	structure	NN
cord-003614-63rzzos3	391	2	and	and	CC
cord-003614-63rzzos3	391	3	function	function	VB
cord-003614-63rzzos3	391	4	A	a	DT
cord-003614-63rzzos3	391	5	double	double	RB
cord-003614-63rzzos3	391	6	-	-	HYPH
cord-003614-63rzzos3	391	7	stranded	strand	VBN
cord-003614-63rzzos3	391	8	RNA	RNA	NNP
cord-003614-63rzzos3	391	9	-	-	HYPH
cord-003614-63rzzos3	391	10	activated	activate	VBN
cord-003614-63rzzos3	391	11	protein	protein	NN
cord-003614-63rzzos3	391	12	kinase	kinase	NN
cord-003614-63rzzos3	391	13	-	-	HYPH
cord-003614-63rzzos3	391	14	dependent	dependent	JJ
cord-003614-63rzzos3	391	15	pathway	pathway	NN
cord-003614-63rzzos3	391	16	mediating	mediate	VBG
cord-003614-63rzzos3	391	17	stress	stress	NN
cord-003614-63rzzos3	391	18	-	-	HYPH
cord-003614-63rzzos3	391	19	induced	induce	VBN
cord-003614-63rzzos3	391	20	apoptosis	apoptosis	NN
cord-003614-63rzzos3	391	21	Essential	essential	JJ
cord-003614-63rzzos3	391	22	role	role	NN
cord-003614-63rzzos3	391	23	for	for	IN
cord-003614-63rzzos3	391	24	the	the	DT
cord-003614-63rzzos3	391	25	dsRNA	dsrna	JJ
cord-003614-63rzzos3	391	26	-	-	HYPH
cord-003614-63rzzos3	391	27	dependent	dependent	JJ
cord-003614-63rzzos3	391	28	protein	protein	NN
cord-003614-63rzzos3	391	29	kinase	kinase	VBZ
cord-003614-63rzzos3	391	30	PKR	PKR	NNP
cord-003614-63rzzos3	391	31	in	in	IN
cord-003614-63rzzos3	391	32	innate	innate	JJ
cord-003614-63rzzos3	391	33	immunity	immunity	NN
cord-003614-63rzzos3	391	34	to	to	IN
cord-003614-63rzzos3	391	35	viral	viral	JJ
cord-003614-63rzzos3	391	36	infection	infection	NN
cord-003614-63rzzos3	392	1	Immunohistochemical	immunohistochemical	JJ
cord-003614-63rzzos3	392	2	localization	localization	NN
cord-003614-63rzzos3	392	3	of	of	IN
cord-003614-63rzzos3	392	4	phosphorylated	phosphorylated	JJ
cord-003614-63rzzos3	392	5	protein	protein	NN
cord-003614-63rzzos3	392	6	kinase	kinase	NN
cord-003614-63rzzos3	392	7	R	r	NN
cord-003614-63rzzos3	392	8	and	and	CC
cord-003614-63rzzos3	392	9	phosphorylated	phosphorylate	VBD
cord-003614-63rzzos3	392	10	eukaryotic	eukaryotic	JJ
cord-003614-63rzzos3	392	11	initiation	initiation	NN
cord-003614-63rzzos3	392	12	factor-2	factor-2	JJ
cord-003614-63rzzos3	392	13	alpha	alpha	NN
cord-003614-63rzzos3	392	14	in	in	IN
cord-003614-63rzzos3	392	15	the	the	DT
cord-003614-63rzzos3	392	16	central	central	JJ
cord-003614-63rzzos3	392	17	nervous	nervous	JJ
cord-003614-63rzzos3	392	18	system	system	NN
cord-003614-63rzzos3	392	19	of	of	IN
cord-003614-63rzzos3	392	20	SJL	SJL	NNP
cord-003614-63rzzos3	392	21	mice	mouse	NNS
cord-003614-63rzzos3	392	22	with	with	IN
cord-003614-63rzzos3	392	23	experimental	experimental	JJ
cord-003614-63rzzos3	392	24	allergic	allergic	JJ
cord-003614-63rzzos3	392	25	encephalomyelitis	encephalomyelitis	NN
cord-003614-63rzzos3	392	26	On	on	IN
cord-003614-63rzzos3	392	27	the	the	DT
cord-003614-63rzzos3	392	28	discovery	discovery	NN
cord-003614-63rzzos3	392	29	of	of	IN
cord-003614-63rzzos3	392	30	interferon	interferon	NN
cord-003614-63rzzos3	392	31	-	-	HYPH
cord-003614-63rzzos3	392	32	inducible	inducible	JJ
cord-003614-63rzzos3	392	33	,	,	,
cord-003614-63rzzos3	392	34	double	double	RB
cord-003614-63rzzos3	392	35	-	-	HYPH
cord-003614-63rzzos3	392	36	stranded	strand	VBN
cord-003614-63rzzos3	392	37	RNA	RNA	NNP
cord-003614-63rzzos3	392	38	activated	activate	VBN
cord-003614-63rzzos3	392	39	enzymes	enzyme	NNS
cord-003614-63rzzos3	392	40	:	:	:
cord-003614-63rzzos3	393	1	The	the	DT
cord-003614-63rzzos3	393	2	2'-5'oligoadenylate	2'-5'oligoadenylate	CD
cord-003614-63rzzos3	393	3	synthetases	synthetase	NNS
cord-003614-63rzzos3	393	4	and	and	CC
cord-003614-63rzzos3	393	5	the	the	DT
cord-003614-63rzzos3	393	6	protein	protein	NN
cord-003614-63rzzos3	393	7	kinase	kinase	VBZ
cord-003614-63rzzos3	393	8	PKR	PKR	NNP
cord-003614-63rzzos3	393	9	.	.	.
cord-003614-63rzzos3	394	1	Cytokine	Cytokine	NNP
cord-003614-63rzzos3	394	2	Growth	Growth	NNP
cord-003614-63rzzos3	394	3	Factor	Factor	NNP
cord-003614-63rzzos3	394	4	Rev	Rev	NNP
cord-003614-63rzzos3	394	5	Continuous	continuous	JJ
cord-003614-63rzzos3	394	6	production	production	NN
cord-003614-63rzzos3	394	7	of	of	IN
cord-003614-63rzzos3	394	8	interferon	interferon	NN
cord-003614-63rzzos3	394	9	in	in	IN
cord-003614-63rzzos3	394	10	normal	normal	JJ
cord-003614-63rzzos3	394	11	mice	mouse	NNS
cord-003614-63rzzos3	394	12	:	:	:
cord-003614-63rzzos3	394	13	Effect	effect	NN
cord-003614-63rzzos3	394	14	of	of	IN
cord-003614-63rzzos3	394	15	anti	anti	JJ
cord-003614-63rzzos3	394	16	-	-	JJ
cord-003614-63rzzos3	394	17	interferon	interferon	JJ
cord-003614-63rzzos3	394	18	globulin	globulin	NN
cord-003614-63rzzos3	394	19	,	,	,
cord-003614-63rzzos3	394	20	sex	sex	NN
cord-003614-63rzzos3	394	21	,	,	,
cord-003614-63rzzos3	394	22	age	age	NN
cord-003614-63rzzos3	394	23	,	,	,
cord-003614-63rzzos3	394	24	strain	strain	NN
cord-003614-63rzzos3	394	25	and	and	CC
cord-003614-63rzzos3	394	26	environment	environment	NN
cord-003614-63rzzos3	394	27	on	on	IN
cord-003614-63rzzos3	394	28	the	the	DT
cord-003614-63rzzos3	394	29	levels	level	NNS
cord-003614-63rzzos3	394	30	of	of	IN
cord-003614-63rzzos3	394	31	2	2	CD
cord-003614-63rzzos3	394	32	-	-	HYPH
cord-003614-63rzzos3	394	33	5A	5a	NN
cord-003614-63rzzos3	394	34	synthetase	synthetase	NN
cord-003614-63rzzos3	394	35	and	and	CC
cord-003614-63rzzos3	394	36	p67	p67	NN
cord-003614-63rzzos3	394	37	K	K	NNP
cord-003614-63rzzos3	394	38	kinase	kinase	NNP
cord-003614-63rzzos3	394	39	Expression	expression	NN
cord-003614-63rzzos3	394	40	of	of	IN
cord-003614-63rzzos3	394	41	interferon	interferon	NN
cord-003614-63rzzos3	394	42	-	-	HYPH
cord-003614-63rzzos3	394	43	induced	induce	VBN
cord-003614-63rzzos3	394	44	genes	gene	NNS
cord-003614-63rzzos3	394	45	in	in	IN
cord-003614-63rzzos3	394	46	different	different	JJ
cord-003614-63rzzos3	394	47	tissues	tissue	NNS
cord-003614-63rzzos3	394	48	of	of	IN
cord-003614-63rzzos3	394	49	mice	mouse	NNS
cord-003614-63rzzos3	394	50	Fascination	fascination	NN
cord-003614-63rzzos3	394	51	with	with	IN
cord-003614-63rzzos3	394	52	2	2	CD
cord-003614-63rzzos3	394	53	-	-	HYPH
cord-003614-63rzzos3	394	54	5A	5a	NN
cord-003614-63rzzos3	394	55	-	-	HYPH
cord-003614-63rzzos3	394	56	dependent	dependent	JJ
cord-003614-63rzzos3	394	57	RNase	rnase	NN
cord-003614-63rzzos3	394	58	:	:	:
cord-003614-63rzzos3	394	59	A	a	DT
cord-003614-63rzzos3	394	60	unique	unique	JJ
cord-003614-63rzzos3	394	61	enzyme	enzyme	NN
cord-003614-63rzzos3	394	62	that	that	WDT
cord-003614-63rzzos3	394	63	functions	function	NNS
cord-003614-63rzzos3	394	64	in	in	IN
cord-003614-63rzzos3	394	65	interferon	interferon	NN
cord-003614-63rzzos3	394	66	action	action	NN
cord-003614-63rzzos3	394	67	Activation	Activation	NNP
cord-003614-63rzzos3	394	68	of	of	IN
cord-003614-63rzzos3	394	69	p38	p38	CD
cord-003614-63rzzos3	394	70	mitogen	mitogen	NNP
cord-003614-63rzzos3	394	71	-	-	HYPH
cord-003614-63rzzos3	394	72	activated	activate	VBN
cord-003614-63rzzos3	394	73	protein	protein	NN
cord-003614-63rzzos3	394	74	kinase	kinase	NN
cord-003614-63rzzos3	394	75	and	and	CC
cord-003614-63rzzos3	395	1	c	c	LS
cord-003614-63rzzos3	395	2	-	-	:
cord-003614-63rzzos3	395	3	Jun	Jun	NNP
cord-003614-63rzzos3	395	4	NH(2)-terminal	NH(2)-terminal	NNP
cord-003614-63rzzos3	395	5	kinase	kinase	NN
cord-003614-63rzzos3	395	6	by	by	IN
cord-003614-63rzzos3	395	7	double	double	RB
cord-003614-63rzzos3	395	8	-	-	HYPH
cord-003614-63rzzos3	395	9	stranded	strand	VBN
cord-003614-63rzzos3	395	10	RNA	RNA	NNP
cord-003614-63rzzos3	395	11	and	and	CC
cord-003614-63rzzos3	395	12	encephalomyocarditis	encephalomyocarditis	NNP
cord-003614-63rzzos3	395	13	virus	virus	NN
cord-003614-63rzzos3	395	14	:	:	:
cord-003614-63rzzos3	395	15	Involvement	involvement	NN
cord-003614-63rzzos3	395	16	of	of	IN
cord-003614-63rzzos3	395	17	RNase	RNase	NNP
cord-003614-63rzzos3	395	18	L	L	NNP
cord-003614-63rzzos3	395	19	,	,	,
cord-003614-63rzzos3	395	20	protein	protein	NN
cord-003614-63rzzos3	395	21	kinase	kinase	NN
cord-003614-63rzzos3	395	22	R	r	NN
cord-003614-63rzzos3	395	23	,	,	,
cord-003614-63rzzos3	395	24	and	and	CC
cord-003614-63rzzos3	395	25	alternative	alternative	JJ
cord-003614-63rzzos3	395	26	pathways	pathway	NNS
cord-003614-63rzzos3	396	1	Inhibition	inhibition	NN
cord-003614-63rzzos3	396	2	of	of	IN
cord-003614-63rzzos3	396	3	the	the	DT
cord-003614-63rzzos3	396	4	OAS	OAS	NNP
cord-003614-63rzzos3	396	5	/	/	SYM
cord-003614-63rzzos3	396	6	RNase	RNase	NNP
cord-003614-63rzzos3	396	7	L	l	NN
cord-003614-63rzzos3	396	8	pathway	pathway	NN
cord-003614-63rzzos3	396	9	by	by	IN
cord-003614-63rzzos3	396	10	viruses	virus	NNS
cord-003614-63rzzos3	396	11	Small	small	JJ
cord-003614-63rzzos3	396	12	self	self	NN
cord-003614-63rzzos3	396	13	-	-	HYPH
cord-003614-63rzzos3	396	14	RNA	rna	NN
cord-003614-63rzzos3	396	15	generated	generate	VBN
cord-003614-63rzzos3	396	16	by	by	IN
cord-003614-63rzzos3	396	17	RNase	RNase	NNP
cord-003614-63rzzos3	396	18	L	L	NNP
cord-003614-63rzzos3	396	19	amplifies	amplify	VBZ
cord-003614-63rzzos3	396	20	antiviral	antiviral	JJ
cord-003614-63rzzos3	396	21	innate	innate	JJ
cord-003614-63rzzos3	396	22	immunity	immunity	NN
cord-003614-63rzzos3	396	23	The	the	DT
cord-003614-63rzzos3	396	24	2	2	CD
cord-003614-63rzzos3	396	25	-	-	HYPH
cord-003614-63rzzos3	396	26	5A	5a	CD
cord-003614-63rzzos3	396	27	system	system	NN
cord-003614-63rzzos3	396	28	in	in	IN
cord-003614-63rzzos3	396	29	viral	viral	JJ
cord-003614-63rzzos3	396	30	infection	infection	NN
cord-003614-63rzzos3	396	31	and	and	CC
cord-003614-63rzzos3	396	32	apoptosis	apoptosis	NN
cord-003614-63rzzos3	397	1	Extracellular	Extracellular	NNP
cord-003614-63rzzos3	397	2	2'-5	2'-5	CD
cord-003614-63rzzos3	397	3	'	'	''
cord-003614-63rzzos3	398	1	oligoadenylate	oligoadenylate	NNP
cord-003614-63rzzos3	398	2	synthetase	synthetase	NNP
cord-003614-63rzzos3	398	3	stimulates	stimulate	VBZ
cord-003614-63rzzos3	398	4	RNase	RNase	NNP
cord-003614-63rzzos3	398	5	L	l	NN
cord-003614-63rzzos3	398	6	-	-	HYPH
cord-003614-63rzzos3	398	7	independent	independent	JJ
cord-003614-63rzzos3	398	8	antiviral	antiviral	JJ
cord-003614-63rzzos3	398	9	activity	activity	NN
cord-003614-63rzzos3	398	10	:	:	:
cord-003614-63rzzos3	398	11	A	a	DT
cord-003614-63rzzos3	398	12	novel	novel	JJ
cord-003614-63rzzos3	398	13	mechanism	mechanism	NN
cord-003614-63rzzos3	398	14	of	of	IN
cord-003614-63rzzos3	398	15	virus	virus	NN
cord-003614-63rzzos3	398	16	-	-	HYPH
cord-003614-63rzzos3	398	17	induced	induce	VBN
cord-003614-63rzzos3	398	18	innate	innate	JJ
cord-003614-63rzzos3	398	19	immunity	immunity	NN
cord-003614-63rzzos3	398	20	Evasion	evasion	NN
cord-003614-63rzzos3	398	21	of	of	IN
cord-003614-63rzzos3	398	22	antiviral	antiviral	JJ
cord-003614-63rzzos3	398	23	innate	innate	JJ
cord-003614-63rzzos3	398	24	immunity	immunity	NN
cord-003614-63rzzos3	398	25	by	by	IN
cord-003614-63rzzos3	398	26	Theiler	Theiler	NNP
cord-003614-63rzzos3	398	27	's	's	POS
cord-003614-63rzzos3	398	28	virus	virus	NN
cord-003614-63rzzos3	398	29	L	l	NN
cord-003614-63rzzos3	398	30	*	*	NFP
cord-003614-63rzzos3	398	31	protein	protein	NN
cord-003614-63rzzos3	398	32	through	through	IN
cord-003614-63rzzos3	398	33	direct	direct	JJ
cord-003614-63rzzos3	398	34	inhibition	inhibition	NN
cord-003614-63rzzos3	398	35	of	of	IN
cord-003614-63rzzos3	398	36	RNase	RNase	NNP
cord-003614-63rzzos3	398	37	L	L	NNP
cord-003614-63rzzos3	398	38	Cell	cell	NN
cord-003614-63rzzos3	398	39	-	-	HYPH
cord-003614-63rzzos3	398	40	type	type	NN
cord-003614-63rzzos3	398	41	-	-	HYPH
cord-003614-63rzzos3	398	42	specific	specific	JJ
cord-003614-63rzzos3	398	43	activation	activation	NN
cord-003614-63rzzos3	398	44	of	of	IN
cord-003614-63rzzos3	398	45	the	the	DT
cord-003614-63rzzos3	398	46	oligoadenylate	oligoadenylate	NNP
cord-003614-63rzzos3	398	47	synthetase	synthetase	NN
cord-003614-63rzzos3	398	48	-	-	HYPH
cord-003614-63rzzos3	398	49	RNase	RNase	NNP
cord-003614-63rzzos3	398	50	L	l	NN
cord-003614-63rzzos3	398	51	pathway	pathway	NN
cord-003614-63rzzos3	398	52	by	by	IN
cord-003614-63rzzos3	398	53	a	a	DT
cord-003614-63rzzos3	398	54	murine	murine	JJ
cord-003614-63rzzos3	398	55	coronavirus	coronavirus	NN
cord-003614-63rzzos3	399	1	A	a	DT
cord-003614-63rzzos3	399	2	full	full	JJ
cord-003614-63rzzos3	399	3	-	-	HYPH
cord-003614-63rzzos3	399	4	length	length	NN
cord-003614-63rzzos3	399	5	murine	murine	JJ
cord-003614-63rzzos3	399	6	2	2	CD
cord-003614-63rzzos3	399	7	-	-	HYPH
cord-003614-63rzzos3	399	8	5A	5a	CD
cord-003614-63rzzos3	399	9	synthetase	synthetase	NN
cord-003614-63rzzos3	399	10	cDNA	cdna	NN
cord-003614-63rzzos3	399	11	transfected	transfecte	VBN
cord-003614-63rzzos3	399	12	in	in	IN
cord-003614-63rzzos3	399	13	NIH-3T3	NIH-3T3	NNP
cord-003614-63rzzos3	399	14	cells	cell	NNS
cord-003614-63rzzos3	399	15	impairs	impair	VBZ
cord-003614-63rzzos3	399	16	EMCV	EMCV	NNP
cord-003614-63rzzos3	399	17	but	but	CC
cord-003614-63rzzos3	399	18	not	not	RB
cord-003614-63rzzos3	399	19	VSV	VSV	NNP
cord-003614-63rzzos3	399	20	replication	replication	NN
cord-003614-63rzzos3	399	21	Constitutive	constitutive	JJ
cord-003614-63rzzos3	399	22	expression	expression	NN
cord-003614-63rzzos3	399	23	of	of	IN
cord-003614-63rzzos3	399	24	(	(	-LRB-
cord-003614-63rzzos3	399	25	2'-5	2'-5	CD
cord-003614-63rzzos3	399	26	'	'	''
cord-003614-63rzzos3	399	27	)	)	-RRB-
cord-003614-63rzzos3	400	1	oligo	oligo	NNP
cord-003614-63rzzos3	401	1	A	a	DT
cord-003614-63rzzos3	401	2	synthetase	synthetase	NN
cord-003614-63rzzos3	401	3	confers	confer	VBZ
cord-003614-63rzzos3	401	4	resistance	resistance	NN
cord-003614-63rzzos3	401	5	to	to	IN
cord-003614-63rzzos3	401	6	picornavirus	picornavirus	NNP
cord-003614-63rzzos3	401	7	infection	infection	NN
cord-003614-63rzzos3	401	8	Constitutive	constitutive	JJ
cord-003614-63rzzos3	401	9	expression	expression	NN
cord-003614-63rzzos3	401	10	of	of	IN
cord-003614-63rzzos3	401	11	a	a	DT
cord-003614-63rzzos3	401	12	2',5'-oligoadenylate	2',5'-oligoadenylate	CD
cord-003614-63rzzos3	401	13	synthetase	synthetase	NN
cord-003614-63rzzos3	401	14	cDNA	cdna	NN
cord-003614-63rzzos3	401	15	results	result	NNS
cord-003614-63rzzos3	401	16	in	in	IN
cord-003614-63rzzos3	401	17	increased	increase	VBN
cord-003614-63rzzos3	401	18	antiviral	antiviral	JJ
cord-003614-63rzzos3	401	19	activity	activity	NN
cord-003614-63rzzos3	401	20	and	and	CC
cord-003614-63rzzos3	401	21	growth	growth	NN
cord-003614-63rzzos3	401	22	suppression	suppression	NN
cord-003614-63rzzos3	401	23	Interferon	Interferon	NNP
cord-003614-63rzzos3	401	24	-	-	HYPH
cord-003614-63rzzos3	401	25	induced	induce	VBN
cord-003614-63rzzos3	401	26	Mx	Mx	NNP
cord-003614-63rzzos3	401	27	proteins	protein	NNS
cord-003614-63rzzos3	401	28	in	in	IN
cord-003614-63rzzos3	401	29	antiviral	antiviral	JJ
cord-003614-63rzzos3	401	30	host	host	NN
cord-003614-63rzzos3	401	31	defense	defense	NN
cord-003614-63rzzos3	401	32	Restricted	restricted	JJ
cord-003614-63rzzos3	401	33	expression	expression	NN
cord-003614-63rzzos3	401	34	of	of	IN
cord-003614-63rzzos3	401	35	viral	viral	JJ
cord-003614-63rzzos3	401	36	surface	surface	NN
cord-003614-63rzzos3	401	37	proteins	protein	NNS
cord-003614-63rzzos3	401	38	in	in	IN
cord-003614-63rzzos3	401	39	canine	canine	JJ
cord-003614-63rzzos3	401	40	distemper	distemper	NN
cord-003614-63rzzos3	401	41	encephalitis	encephalitis	NN
cord-003614-63rzzos3	401	42	Astrocytic	astrocytic	JJ
cord-003614-63rzzos3	401	43	infection	infection	NN
cord-003614-63rzzos3	401	44	in	in	IN
cord-003614-63rzzos3	401	45	canine	canine	JJ
cord-003614-63rzzos3	401	46	distemper	distemper	NN
cord-003614-63rzzos3	401	47	virus	virus	NN
cord-003614-63rzzos3	401	48	-	-	HYPH
cord-003614-63rzzos3	401	49	induced	induce	VBN
cord-003614-63rzzos3	401	50	demyelination	demyelination	NN
cord-003614-63rzzos3	401	51	Oligodendroglial	Oligodendroglial	NNP
cord-003614-63rzzos3	401	52	pathology	pathology	NN
cord-003614-63rzzos3	401	53	in	in	IN
cord-003614-63rzzos3	401	54	canine	canine	JJ
cord-003614-63rzzos3	401	55	distemper	distemper	NN
cord-003614-63rzzos3	402	1	Axonal	axonal	JJ
cord-003614-63rzzos3	402	2	pathology	pathology	NN
cord-003614-63rzzos3	402	3	and	and	CC
cord-003614-63rzzos3	402	4	loss	loss	NN
cord-003614-63rzzos3	402	5	precede	precede	VBP
cord-003614-63rzzos3	402	6	demyelination	demyelination	NN
cord-003614-63rzzos3	402	7	and	and	CC
cord-003614-63rzzos3	402	8	accompany	accompany	VBP
cord-003614-63rzzos3	402	9	chronic	chronic	JJ
cord-003614-63rzzos3	402	10	lesions	lesion	NNS
cord-003614-63rzzos3	402	11	in	in	IN
cord-003614-63rzzos3	402	12	a	a	DT
cord-003614-63rzzos3	402	13	spontaneously	spontaneously	RB
cord-003614-63rzzos3	402	14	occurring	occur	VBG
cord-003614-63rzzos3	402	15	animal	animal	NN
cord-003614-63rzzos3	402	16	model	model	NN
cord-003614-63rzzos3	402	17	of	of	IN
cord-003614-63rzzos3	402	18	multiple	multiple	JJ
cord-003614-63rzzos3	402	19	sclerosis	sclerosis	NN
cord-003614-63rzzos3	403	1	The	the	DT
cord-003614-63rzzos3	403	2	neurobiology	neurobiology	NN
cord-003614-63rzzos3	403	3	of	of	IN
cord-003614-63rzzos3	403	4	canine	canine	JJ
cord-003614-63rzzos3	403	5	distemper	distemper	NN
cord-003614-63rzzos3	403	6	virus	virus	NN
cord-003614-63rzzos3	403	7	infection	infection	NN
cord-003614-63rzzos3	403	8	Up	up	IN
cord-003614-63rzzos3	403	9	-	-	HYPH
cord-003614-63rzzos3	403	10	regulation	regulation	NN
cord-003614-63rzzos3	403	11	of	of	IN
cord-003614-63rzzos3	403	12	mRNA	mrna	NN
cord-003614-63rzzos3	403	13	for	for	IN
cord-003614-63rzzos3	403	14	matrix	matrix	NN
cord-003614-63rzzos3	403	15	metalloproteinases-9	metalloproteinases-9	NNP
cord-003614-63rzzos3	403	16	and	and	CC
cord-003614-63rzzos3	403	17	-14	-14	NN
cord-003614-63rzzos3	403	18	in	in	IN
cord-003614-63rzzos3	403	19	advanced	advanced	JJ
cord-003614-63rzzos3	403	20	lesions	lesion	NNS
cord-003614-63rzzos3	403	21	of	of	IN
cord-003614-63rzzos3	403	22	demyelinating	demyelinate	VBG
cord-003614-63rzzos3	403	23	canine	canine	JJ
cord-003614-63rzzos3	403	24	distemper	distemper	NN
cord-003614-63rzzos3	403	25	leukoencephalitis	leukoencephalitis	NNP
cord-003614-63rzzos3	403	26	Phase	phase	NN
cord-003614-63rzzos3	403	27	-	-	HYPH
cord-003614-63rzzos3	403	28	dependent	dependent	JJ
cord-003614-63rzzos3	403	29	expression	expression	NN
cord-003614-63rzzos3	403	30	of	of	IN
cord-003614-63rzzos3	403	31	matrix	matrix	NN
cord-003614-63rzzos3	403	32	metalloproteinases	metalloproteinase	NNS
cord-003614-63rzzos3	403	33	and	and	CC
cord-003614-63rzzos3	403	34	their	-PRON-	PRP$
cord-003614-63rzzos3	403	35	inhibitors	inhibitor	NNS
cord-003614-63rzzos3	403	36	in	in	IN
cord-003614-63rzzos3	403	37	demyelinating	demyelinate	VBG
cord-003614-63rzzos3	403	38	canine	canine	JJ
cord-003614-63rzzos3	403	39	distemper	distemper	NN
cord-003614-63rzzos3	403	40	encephalitis	encephalitis	NN
cord-003614-63rzzos3	403	41	Repertoire	repertoire	NN
cord-003614-63rzzos3	403	42	of	of	IN
cord-003614-63rzzos3	403	43	microglial	microglial	JJ
cord-003614-63rzzos3	403	44	and	and	CC
cord-003614-63rzzos3	403	45	macrophage	macrophage	NN
cord-003614-63rzzos3	403	46	responses	response	NNS
cord-003614-63rzzos3	403	47	after	after	IN
cord-003614-63rzzos3	403	48	spinal	spinal	JJ
cord-003614-63rzzos3	403	49	cord	cord	NN
cord-003614-63rzzos3	403	50	injury	injury	NN
cord-003614-63rzzos3	403	51	Interleukin-1beta	interleukin-1beta	NN
cord-003614-63rzzos3	403	52	,	,	,
cord-003614-63rzzos3	403	53	-6	-6	NNP
cord-003614-63rzzos3	403	54	,	,	,
cord-003614-63rzzos3	403	55	-12	-12	NN
cord-003614-63rzzos3	403	56	and	and	CC
cord-003614-63rzzos3	403	57	tumor	tumor	NN
cord-003614-63rzzos3	403	58	necrosis	necrosis	NN
cord-003614-63rzzos3	403	59	factor	factor	NN
cord-003614-63rzzos3	403	60	-	-	HYPH
cord-003614-63rzzos3	403	61	alpha	alpha	NN
cord-003614-63rzzos3	403	62	expression	expression	NN
cord-003614-63rzzos3	403	63	in	in	IN
cord-003614-63rzzos3	403	64	brains	brain	NNS
cord-003614-63rzzos3	403	65	of	of	IN
cord-003614-63rzzos3	403	66	dogs	dog	NNS
cord-003614-63rzzos3	403	67	with	with	IN
cord-003614-63rzzos3	403	68	canine	canine	JJ
cord-003614-63rzzos3	403	69	distemper	distemper	NN
cord-003614-63rzzos3	403	70	virus	virus	NN
cord-003614-63rzzos3	403	71	infection	infection	NN
cord-003614-63rzzos3	403	72	Early	early	RB
cord-003614-63rzzos3	403	73	T	T	NNP
cord-003614-63rzzos3	403	74	cell	cell	NN
cord-003614-63rzzos3	403	75	response	response	NN
cord-003614-63rzzos3	403	76	in	in	IN
cord-003614-63rzzos3	403	77	the	the	DT
cord-003614-63rzzos3	403	78	central	central	JJ
cord-003614-63rzzos3	403	79	nervous	nervous	JJ
cord-003614-63rzzos3	403	80	system	system	NN
cord-003614-63rzzos3	403	81	in	in	IN
cord-003614-63rzzos3	403	82	canine	canine	JJ
cord-003614-63rzzos3	403	83	distemper	distemper	NN
cord-003614-63rzzos3	403	84	virus	virus	NN
cord-003614-63rzzos3	403	85	infection	infection	NN
cord-003614-63rzzos3	403	86	Identification	identification	NN
cord-003614-63rzzos3	403	87	of	of	IN
cord-003614-63rzzos3	403	88	CD4	CD4	NNP
cord-003614-63rzzos3	403	89	+	+	CC
cord-003614-63rzzos3	403	90	and	and	CC
cord-003614-63rzzos3	403	91	CD8	CD8	NNP
cord-003614-63rzzos3	403	92	+	+	CC
cord-003614-63rzzos3	403	93	T	T	NNP
cord-003614-63rzzos3	403	94	cell	cell	NN
cord-003614-63rzzos3	403	95	subsets	subset	NNS
cord-003614-63rzzos3	403	96	and	and	CC
cord-003614-63rzzos3	403	97	B	b	NN
cord-003614-63rzzos3	403	98	cells	cell	NNS
cord-003614-63rzzos3	403	99	in	in	IN
cord-003614-63rzzos3	403	100	the	the	DT
cord-003614-63rzzos3	403	101	brain	brain	NN
cord-003614-63rzzos3	403	102	of	of	IN
cord-003614-63rzzos3	403	103	dogs	dog	NNS
cord-003614-63rzzos3	403	104	with	with	IN
cord-003614-63rzzos3	403	105	spontaneous	spontaneous	JJ
cord-003614-63rzzos3	403	106	acute	acute	NN
cord-003614-63rzzos3	403	107	,	,	,
cord-003614-63rzzos3	403	108	subacute-	subacute-	JJ
cord-003614-63rzzos3	403	109	,	,	,
cord-003614-63rzzos3	403	110	and	and	CC
cord-003614-63rzzos3	404	1	chronic	chronic	JJ
cord-003614-63rzzos3	404	2	-	-	HYPH
cord-003614-63rzzos3	404	3	demyelinating	demyelinate	VBG
cord-003614-63rzzos3	404	4	distemper	distemper	NN
cord-003614-63rzzos3	404	5	encephalitis	encephalitis	NN
cord-003614-63rzzos3	404	6	IRF1	IRF1	NNP
cord-003614-63rzzos3	404	7	Is	be	VBZ
cord-003614-63rzzos3	404	8	a	a	DT
cord-003614-63rzzos3	404	9	Transcriptional	Transcriptional	NNP
cord-003614-63rzzos3	404	10	Regulator	Regulator	NNP
cord-003614-63rzzos3	404	11	of	of	IN
cord-003614-63rzzos3	404	12	ZBP1	ZBP1	NNP
cord-003614-63rzzos3	404	13	Promoting	Promoting	NNP
cord-003614-63rzzos3	404	14	NLRP3	NLRP3	NNP
cord-003614-63rzzos3	404	15	Inflammasome	Inflammasome	NNP
cord-003614-63rzzos3	404	16	Activation	Activation	NNP
cord-003614-63rzzos3	404	17	and	and	CC
cord-003614-63rzzos3	404	18	Cell	Cell	NNP
cord-003614-63rzzos3	404	19	Death	death	NN
cord-003614-63rzzos3	404	20	during	during	IN
cord-003614-63rzzos3	404	21	Influenza	Influenza	NNP
cord-003614-63rzzos3	404	22	Virus	Virus	NNP
cord-003614-63rzzos3	404	23	Infection	Infection	NNP
cord-003614-63rzzos3	404	24	Microglial	Microglial	NNP
cord-003614-63rzzos3	405	1	Interferon	Interferon	NNP
cord-003614-63rzzos3	405	2	Signaling	Signaling	NNP
cord-003614-63rzzos3	405	3	and	and	CC
cord-003614-63rzzos3	405	4	White	White	NNP
cord-003614-63rzzos3	405	5	Matter	Matter	NNP
cord-003614-63rzzos3	406	1	Interferons	interferon	NNS
cord-003614-63rzzos3	406	2	inhibit	inhibit	VBP
cord-003614-63rzzos3	406	3	tumor	tumor	NN
cord-003614-63rzzos3	406	4	necrosis	necrosis	NN
cord-003614-63rzzos3	406	5	factor	factor	NN
cord-003614-63rzzos3	406	6	-	-	HYPH
cord-003614-63rzzos3	406	7	alpha	alpha	NN
cord-003614-63rzzos3	406	8	-	-	HYPH
cord-003614-63rzzos3	406	9	mediated	mediate	VBN
cord-003614-63rzzos3	406	10	matrix	matrix	NN
cord-003614-63rzzos3	406	11	metalloproteinase-9	metalloproteinase-9	NNP
cord-003614-63rzzos3	406	12	activation	activation	NN
cord-003614-63rzzos3	406	13	via	via	IN
cord-003614-63rzzos3	406	14	interferon	interferon	NN
cord-003614-63rzzos3	406	15	regulatory	regulatory	JJ
cord-003614-63rzzos3	406	16	factor-1	factor-1	NNP
cord-003614-63rzzos3	406	17	binding	bind	VBG
cord-003614-63rzzos3	406	18	competition	competition	NN
cord-003614-63rzzos3	406	19	with	with	IN
cord-003614-63rzzos3	406	20	NF	nf	NN
cord-003614-63rzzos3	406	21	-	-	HYPH
cord-003614-63rzzos3	406	22	kappa	kappa	NN
cord-003614-63rzzos3	406	23	B	B	NNP
cord-003614-63rzzos3	406	24	Regulation	regulation	NN
cord-003614-63rzzos3	406	25	of	of	IN
cord-003614-63rzzos3	406	26	immunity	immunity	NN
cord-003614-63rzzos3	406	27	and	and	CC
cord-003614-63rzzos3	406	28	oncogenesis	oncogenesis	NN
cord-003614-63rzzos3	406	29	by	by	IN
cord-003614-63rzzos3	406	30	the	the	DT
cord-003614-63rzzos3	406	31	IRF	IRF	NNP
cord-003614-63rzzos3	406	32	transcription	transcription	NN
cord-003614-63rzzos3	406	33	factor	factor	NN
cord-003614-63rzzos3	406	34	family	family	NN
cord-003614-63rzzos3	406	35	Targeting	target	VBG
cord-003614-63rzzos3	406	36	interferon	interferon	NN
cord-003614-63rzzos3	406	37	regulatory	regulatory	JJ
cord-003614-63rzzos3	406	38	factors	factor	NNS
cord-003614-63rzzos3	406	39	to	to	TO
cord-003614-63rzzos3	406	40	inhibit	inhibit	VB
cord-003614-63rzzos3	406	41	activation	activation	NN
cord-003614-63rzzos3	406	42	of	of	IN
cord-003614-63rzzos3	406	43	the	the	DT
cord-003614-63rzzos3	406	44	type	type	NN
cord-003614-63rzzos3	407	1	I	-PRON-	PRP
cord-003614-63rzzos3	407	2	IFN	IFN	NNP
cord-003614-63rzzos3	407	3	response	response	NN
cord-003614-63rzzos3	407	4	:	:	:
cord-003614-63rzzos3	407	5	Implications	implication	NNS
cord-003614-63rzzos3	407	6	for	for	IN
cord-003614-63rzzos3	407	7	treatment	treatment	NN
cord-003614-63rzzos3	407	8	of	of	IN
cord-003614-63rzzos3	407	9	autoimmune	autoimmune	JJ
cord-003614-63rzzos3	407	10	disorders	disorder	NNS
cord-003614-63rzzos3	408	1	Synoviocyte	Synoviocyte	NNP
cord-003614-63rzzos3	408	2	innate	innate	VBP
cord-003614-63rzzos3	408	3	immune	immune	JJ
cord-003614-63rzzos3	408	4	responses	response	NNS
cord-003614-63rzzos3	408	5	:	:	:
cord-003614-63rzzos3	408	6	II	II	NNP
cord-003614-63rzzos3	408	7	.	.	.
cord-003614-63rzzos3	409	1	Pivotal	pivotal	JJ
cord-003614-63rzzos3	409	2	role	role	NN
cord-003614-63rzzos3	409	3	of	of	IN
cord-003614-63rzzos3	409	4	IFN	IFN	NNP
cord-003614-63rzzos3	409	5	regulatory	regulatory	JJ
cord-003614-63rzzos3	409	6	factor	factor	NN
cord-003614-63rzzos3	409	7	3	3	CD
cord-003614-63rzzos3	409	8	Poly(I	Poly(I	NNS
cord-003614-63rzzos3	409	9	:	:	:
cord-003614-63rzzos3	409	10	C	C	NNP
cord-003614-63rzzos3	409	11	)	)	-RRB-
cord-003614-63rzzos3	409	12	induces	induce	VBZ
cord-003614-63rzzos3	409	13	expressions	expression	NNS
cord-003614-63rzzos3	409	14	of	of	IN
cord-003614-63rzzos3	409	15	MMP-1	MMP-1	NNP
cord-003614-63rzzos3	409	16	,	,	,
cord-003614-63rzzos3	409	17	-2	-2	NNP
cord-003614-63rzzos3	409	18	,	,	,
cord-003614-63rzzos3	409	19	and	and	CC
cord-003614-63rzzos3	409	20	-3	-3	NNP
cord-003614-63rzzos3	409	21	through	through	IN
cord-003614-63rzzos3	409	22	various	various	JJ
cord-003614-63rzzos3	409	23	signaling	signal	VBG
cord-003614-63rzzos3	409	24	pathways	pathway	NNS
cord-003614-63rzzos3	409	25	including	include	VBG
cord-003614-63rzzos3	409	26	IRF3	IRF3	NNP
cord-003614-63rzzos3	409	27	in	in	IN
cord-003614-63rzzos3	409	28	human	human	JJ
cord-003614-63rzzos3	409	29	skin	skin	NN
cord-003614-63rzzos3	409	30	fibroblasts	fibroblast	NNS
cord-003614-63rzzos3	410	1	Therapeutic	therapeutic	JJ
cord-003614-63rzzos3	410	2	Approaches	approach	NNS
cord-003614-63rzzos3	410	3	to	to	TO
cord-003614-63rzzos3	410	4	Type	type	NN
cord-003614-63rzzos3	411	1	I	-PRON-	PRP
cord-003614-63rzzos3	412	1	Interferonopathies	Interferonopathies	NNP
cord-003614-63rzzos3	413	1	The	the	DT
cord-003614-63rzzos3	414	1	Type	type	NN
cord-003614-63rzzos3	414	2	I	-PRON-	PRP
cord-003614-63rzzos3	414	3	Interferonopathies	Interferonopathies	NNP
cord-003614-63rzzos3	414	4	Type	type	NN
cord-003614-63rzzos3	415	1	I	-PRON-	PRP
cord-003614-63rzzos3	415	2	interferon	interferon	NN
cord-003614-63rzzos3	415	3	-	-	HYPH
cord-003614-63rzzos3	415	4	mediated	mediate	VBN
cord-003614-63rzzos3	415	5	monogenic	monogenic	NNP
cord-003614-63rzzos3	415	6	autoinflammation	autoinflammation	NN
cord-003614-63rzzos3	415	7	:	:	:
cord-003614-63rzzos3	416	1	The	the	DT
cord-003614-63rzzos3	416	2	type	type	NN
cord-003614-63rzzos3	416	3	I	-PRON-	PRP
cord-003614-63rzzos3	416	4	interferonopathies	interferonopathie	VBD
cord-003614-63rzzos3	416	5	,	,	,
cord-003614-63rzzos3	416	6	a	a	DT
cord-003614-63rzzos3	416	7	conceptual	conceptual	JJ
cord-003614-63rzzos3	416	8	overview	overview	NN
cord-003614-63rzzos3	416	9	Up	up	IN
cord-003614-63rzzos3	416	10	-	-	HYPH
cord-003614-63rzzos3	416	11	regulation	regulation	NN
cord-003614-63rzzos3	416	12	of	of	IN
cord-003614-63rzzos3	416	13	major	major	JJ
cord-003614-63rzzos3	416	14	histocompatibility	histocompatibility	NN
cord-003614-63rzzos3	416	15	complex	complex	JJ
cord-003614-63rzzos3	416	16	class	class	NN
cord-003614-63rzzos3	416	17	II	II	NNP
cord-003614-63rzzos3	416	18	antigen	antigen	NN
cord-003614-63rzzos3	416	19	expression	expression	NN
cord-003614-63rzzos3	416	20	in	in	IN
cord-003614-63rzzos3	416	21	the	the	DT
cord-003614-63rzzos3	416	22	central	central	JJ
cord-003614-63rzzos3	416	23	nervous	nervous	JJ
cord-003614-63rzzos3	416	24	system	system	NN
cord-003614-63rzzos3	416	25	of	of	IN
cord-003614-63rzzos3	416	26	dogs	dog	NNS
cord-003614-63rzzos3	416	27	with	with	IN
cord-003614-63rzzos3	416	28	spontaneous	spontaneous	JJ
cord-003614-63rzzos3	416	29	canine	canine	JJ
cord-003614-63rzzos3	416	30	distemper	distemper	NN
cord-003614-63rzzos3	416	31	virus	virus	NN
cord-003614-63rzzos3	416	32	encephalitis	encephalitis	RB
cord-003614-63rzzos3	417	1	The	the	DT
cord-003614-63rzzos3	417	2	yin	yin	NNP
cord-003614-63rzzos3	417	3	and	and	CC
cord-003614-63rzzos3	417	4	yang	yang	NNP
cord-003614-63rzzos3	417	5	of	of	IN
cord-003614-63rzzos3	417	6	viruses	virus	NNS
cord-003614-63rzzos3	417	7	and	and	CC
cord-003614-63rzzos3	417	8	interferons	interferon	NNS
cord-003614-63rzzos3	418	1	Interferon	interferon	NN
cord-003614-63rzzos3	418	2	-	-	HYPH
cord-003614-63rzzos3	418	3	stimulated	stimulate	VBN
cord-003614-63rzzos3	418	4	genes	gene	NNS
cord-003614-63rzzos3	418	5	:	:	:
cord-003614-63rzzos3	418	6	Roles	role	NNS
cord-003614-63rzzos3	418	7	in	in	IN
cord-003614-63rzzos3	418	8	viral	viral	JJ
cord-003614-63rzzos3	418	9	pathogenesis	pathogenesis	NN
cord-003614-63rzzos3	418	10	MADGene	madgene	NN
cord-003614-63rzzos3	418	11	:	:	:
cord-003614-63rzzos3	418	12	Retrieval	Retrieval	NNP
cord-003614-63rzzos3	418	13	and	and	CC
cord-003614-63rzzos3	418	14	processing	processing	NN
cord-003614-63rzzos3	418	15	of	of	IN
cord-003614-63rzzos3	418	16	gene	gene	NN
cord-003614-63rzzos3	418	17	identifier	identifier	NN
cord-003614-63rzzos3	418	18	lists	list	NNS
cord-003614-63rzzos3	418	19	for	for	IN
cord-003614-63rzzos3	418	20	the	the	DT
cord-003614-63rzzos3	418	21	analysis	analysis	NN
cord-003614-63rzzos3	418	22	of	of	IN
cord-003614-63rzzos3	418	23	heterogeneous	heterogeneous	JJ
cord-003614-63rzzos3	418	24	microarray	microarray	NN
cord-003614-63rzzos3	418	25	datasets	dataset	NNS
cord-003614-63rzzos3	418	26	The	the	DT
cord-003614-63rzzos3	418	27	authors	author	NNS
cord-003614-63rzzos3	418	28	wish	wish	VBP
cord-003614-63rzzos3	418	29	to	to	TO
cord-003614-63rzzos3	418	30	thank	thank	VB
cord-003614-63rzzos3	418	31	Bettina	Bettina	NNP
cord-003614-63rzzos3	418	32	Buck	Buck	NNP
cord-003614-63rzzos3	418	33	,	,	,
cord-003614-63rzzos3	418	34	Caroline	Caroline	NNP
cord-003614-63rzzos3	418	35	Schütz	Schütz	NNP
cord-003614-63rzzos3	418	36	,	,	,
cord-003614-63rzzos3	418	37	Kerstin	Kerstin	NNP
cord-003614-63rzzos3	418	38	Schöne	Schöne	NNP
cord-003614-63rzzos3	418	39	and	and	CC
cord-003614-63rzzos3	418	40	Petra	Petra	NNP
cord-003614-63rzzos3	418	41	Grünig	Grünig	NNP
cord-003614-63rzzos3	418	42	for	for	IN
cord-003614-63rzzos3	418	43	their	-PRON-	PRP$
cord-003614-63rzzos3	418	44	excellent	excellent	JJ
cord-003614-63rzzos3	418	45	technical	technical	JJ
cord-003614-63rzzos3	418	46	assistance	assistance	NN
cord-003614-63rzzos3	418	47	.	.	.
cord-003614-63rzzos3	419	1	Furthermore	furthermore	RB
cord-003614-63rzzos3	419	2	,	,	,
cord-003614-63rzzos3	419	3	we	-PRON-	PRP
cord-003614-63rzzos3	419	4	would	would	MD
cord-003614-63rzzos3	419	5	like	like	VB
cord-003614-63rzzos3	419	6	to	to	TO
cord-003614-63rzzos3	419	7	thank	thank	VB
cord-003614-63rzzos3	419	8	A.	A.	NNP
cord-003614-63rzzos3	419	9	Zurbriggen	Zurbriggen	NNP
cord-003614-63rzzos3	419	10	(	(	-LRB-
cord-003614-63rzzos3	419	11	University	University	NNP
cord-003614-63rzzos3	419	12	of	of	IN
cord-003614-63rzzos3	419	13	Bern	Bern	NNP
cord-003614-63rzzos3	419	14	,	,	,
cord-003614-63rzzos3	419	15	Switzerland	Switzerland	NNP
cord-003614-63rzzos3	419	16	)	)	-RRB-
cord-003614-63rzzos3	419	17	and	and	CC
cord-003614-63rzzos3	419	18	C.	C.	NNP
cord-003614-63rzzos3	419	19	Örvell	Örvell	NNP
cord-003614-63rzzos3	419	20	(	(	-LRB-
cord-003614-63rzzos3	419	21	Karolinska	Karolinska	NNP
cord-003614-63rzzos3	419	22	University	University	NNP
cord-003614-63rzzos3	419	23	Hospital	Hospital	NNP
cord-003614-63rzzos3	419	24	,	,	,
cord-003614-63rzzos3	419	25	Stockholm	Stockholm	NNP
cord-003614-63rzzos3	419	26	,	,	,
cord-003614-63rzzos3	419	27	Sweden	Sweden	NNP
cord-003614-63rzzos3	419	28	)	)	-RRB-
cord-003614-63rzzos3	419	29	for	for	IN
cord-003614-63rzzos3	419	30	providing	provide	VBG
cord-003614-63rzzos3	419	31	the	the	DT
cord-003614-63rzzos3	419	32	antibodies	antibody	NNS
cord-003614-63rzzos3	419	33	against	against	IN
cord-003614-63rzzos3	419	34	CDV	CDV	NNP
cord-003614-63rzzos3	419	35	and	and	CC
cord-003614-63rzzos3	419	36	O.	O.	NNP
cord-003614-63rzzos3	419	37	Haller	Haller	NNP
cord-003614-63rzzos3	419	38	and	and	CC
cord-003614-63rzzos3	419	39	G.	G.	NNP
cord-003614-63rzzos3	419	40	Kochs	Kochs	NNP
cord-003614-63rzzos3	420	1	(	(	-LRB-
cord-003614-63rzzos3	420	2	University	University	NNP
cord-003614-63rzzos3	420	3	Medical	Medical	NNP
cord-003614-63rzzos3	420	4	Center	Center	NNP
cord-003614-63rzzos3	420	5	Freiburg	Freiburg	NNP
cord-003614-63rzzos3	420	6	,	,	,
cord-003614-63rzzos3	420	7	Germany	Germany	NNP
cord-003614-63rzzos3	420	8	)	)	-RRB-
cord-003614-63rzzos3	420	9	for	for	IN
cord-003614-63rzzos3	420	10	providing	provide	VBG
cord-003614-63rzzos3	420	11	the	the	DT
cord-003614-63rzzos3	420	12	antibody	antibody	NN
cord-003614-63rzzos3	420	13	against	against	IN
cord-003614-63rzzos3	420	14	MX	MX	NNP
cord-003614-63rzzos3	420	15	.	.	.