id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-149069-gpnaldjk	Gomes, M. Gabriela M.	A pragmatic approach to account for individual risks to optimise health policy	2020-09-02		.txt	text/plain	2400	113	33	As the virus spreads in the human population, individuals at higher risk are predominantly infected as indicated at endemic equilibrium (Figure 1 A, B , C, density plots on the right, coloured red) and after 100 years of control (Figure 1 D, E, F). The control strategy applied to endemic equilibrium in the figure is the 90-90-90 treatment as prevention target advocated by the Joint United Nations Programme on HIV/AIDS 4 whereby 90% of infected individuals should be detected, with 90% of these receiving antiretroviral therapy, and 90% of these should achieve viral suppression (becoming effectively non-infectious). Selection on individual variation in disease susceptibility thus offers an explanation for vaccine efficacy trends that is entirely based on population level heterogeneity, in contrast with waning vaccine-induced immunity, an individual-level effect 20 .	./cache/cord-149069-gpnaldjk.txt	./txt/cord-149069-gpnaldjk.txt