id author title date pages extension mime words sentences flesch summary cache txt cord-022544-7jn4ns6x Lawrence, Robert M. Host-Resistance Factors and Immunologic Significance of Human Milk 2010-12-27 .txt text/plain 22268 1177 45 The immunologically active components of breast milk make up an important aspect of the host defenses of the mammary gland in the mother; at the same time, they complement, supplement, and stimulate the ongoing development of the infant' s immune system. A number of other long-term studies demonstrated greater protection from infection with increased exclusivity of breastfeeding and durations of at least 3 months.* A couple papers demonstrated a "dose" effect relative to decreased occurrence of late onset sepsis in very low-birth-weight infants 73 and premature infants 245 associated with the infants receiving at least 50 mL/kg per day of mother' s milk compared with receiving other nutrition. Evidence shows that neutrophils found in human milk demonstrate signs of activation, including increased expression of CD11b (an adherence glycoprotein), decreased expression of L-selectin, spontaneous production of granulocyte-macrophage colony-stimulating factor (GM-CSF), and the ability to transform into CD1 + dendritic cells (DCs). ./cache/cord-022544-7jn4ns6x.txt ./txt/cord-022544-7jn4ns6x.txt