id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-001154-7k59ogn0	Memoli, Matthew J.	The Natural History of Influenza Infection in the Severely Immunocompromised vs Nonimmunocompromised Hosts	2013-11-01		.txt	text/plain	3912	200	31	Evaluation of viral shedding, nasal and serum cytokines, clinical illness, and clinical outcomes were performed to compare severely immunocompromised individuals to nonimmunocompromised individuals with influenza infection. Immunocompromised patients with influenza had more severe disease/complications, longer viral shedding, and more antiviral resistance while demonstrating less clinical symptoms and signs on clinical assessment. Careful examination of symptoms and signs of infection, virological measurements, immunological studies, and clinical parameters were performed to investigate the natural pathogenesis of influenza in this group of severely immunocompromised hosts. The comparison of these individuals with nonimmunocompromised individuals during influenza infection demonstrated that the immunocompromised patients are at risk of more severe or complicated disease, which may be difficult to prevent with current vaccines and treat with current antivirals.	./cache/cord-001154-7k59ogn0.txt	./txt/cord-001154-7k59ogn0.txt