id sid tid token lemma pos cord-296469-h0ma163u 1 1 key key JJ cord-296469-h0ma163u 1 2 : : : cord-296469-h0ma163u 1 3 cord-296469-h0ma163u cord-296469-h0ma163u NNP cord-296469-h0ma163u 1 4 authors author NNS cord-296469-h0ma163u 1 5 : : : cord-296469-h0ma163u 1 6 Gellin Gellin NNP cord-296469-h0ma163u 1 7 , , , cord-296469-h0ma163u 1 8 Bruce Bruce NNP cord-296469-h0ma163u 1 9 G. G. NNP cord-296469-h0ma163u 1 10 ; ; : cord-296469-h0ma163u 1 11 Qadri Qadri NNP cord-296469-h0ma163u 1 12 , , , cord-296469-h0ma163u 1 13 Firdausi Firdausi NNP cord-296469-h0ma163u 1 14 title title NN cord-296469-h0ma163u 1 15 : : : cord-296469-h0ma163u 1 16 Preparing prepare VBG cord-296469-h0ma163u 1 17 for for IN cord-296469-h0ma163u 1 18 the the DT cord-296469-h0ma163u 1 19 unpredictable unpredictable JJ cord-296469-h0ma163u 1 20 : : : cord-296469-h0ma163u 1 21 The the DT cord-296469-h0ma163u 1 22 continuing continue VBG cord-296469-h0ma163u 1 23 need need NN cord-296469-h0ma163u 1 24 for for IN cord-296469-h0ma163u 1 25 pandemic pandemic NN cord-296469-h0ma163u 1 26 influenza influenza NN cord-296469-h0ma163u 1 27 preparedness preparedness NN cord-296469-h0ma163u 1 28 date date NN cord-296469-h0ma163u 1 29 : : : cord-296469-h0ma163u 1 30 2016 2016 CD cord-296469-h0ma163u 1 31 - - SYM cord-296469-h0ma163u 1 32 10 10 CD cord-296469-h0ma163u 1 33 - - SYM cord-296469-h0ma163u 1 34 26 26 CD cord-296469-h0ma163u 1 35 journal journal NN cord-296469-h0ma163u 1 36 : : : cord-296469-h0ma163u 2 1 Vaccine vaccine NN cord-296469-h0ma163u 2 2 DOI doi NN cord-296469-h0ma163u 2 3 : : : cord-296469-h0ma163u 2 4 10.1016 10.1016 CD cord-296469-h0ma163u 3 1 /j.vaccine.2016.09.023 /j.vaccine.2016.09.023 NFP cord-296469-h0ma163u 3 2 sha sha NNP cord-296469-h0ma163u 3 3 : : : cord-296469-h0ma163u 4 1 0a4cd3294e9e451b3fb72b290be6222cd0236523 0a4cd3294e9e451b3fb72b290be6222cd0236523 LS cord-296469-h0ma163u 4 2 doc_id doc_id NNP cord-296469-h0ma163u 5 1 : : : cord-296469-h0ma163u 5 2 296469 296469 CD cord-296469-h0ma163u 5 3 cord_uid cord_uid NNS cord-296469-h0ma163u 5 4 : : : cord-296469-h0ma163u 6 1 h0ma163u h0ma163u NNP cord-296469-h0ma163u 7 1 nan nan NNP cord-296469-h0ma163u 7 2 Preparing prepare VBG cord-296469-h0ma163u 7 3 for for IN cord-296469-h0ma163u 7 4 the the DT cord-296469-h0ma163u 7 5 unpredictable unpredictable JJ cord-296469-h0ma163u 7 6 : : : cord-296469-h0ma163u 7 7 The the DT cord-296469-h0ma163u 7 8 continuing continue VBG cord-296469-h0ma163u 7 9 need need NN cord-296469-h0ma163u 7 10 for for IN cord-296469-h0ma163u 7 11 pandemic pandemic NN cord-296469-h0ma163u 7 12 influenza influenza NN cord-296469-h0ma163u 7 13 preparedness preparedness NN cord-296469-h0ma163u 7 14 Ebola Ebola NNP cord-296469-h0ma163u 7 15 , , , cord-296469-h0ma163u 7 16 Zika Zika NNP cord-296469-h0ma163u 7 17 , , , cord-296469-h0ma163u 7 18 Middle Middle NNP cord-296469-h0ma163u 7 19 East East NNP cord-296469-h0ma163u 7 20 respiratory respiratory JJ cord-296469-h0ma163u 7 21 syndrome syndrome NN cord-296469-h0ma163u 7 22 ( ( -LRB- cord-296469-h0ma163u 7 23 MERS MERS NNP cord-296469-h0ma163u 7 24 ) ) -RRB- cord-296469-h0ma163u 7 25 , , , cord-296469-h0ma163u 7 26 Chikungunya Chikungunya NNP cord-296469-h0ma163u 7 27 , , , cord-296469-h0ma163u 7 28 Severe severe JJ cord-296469-h0ma163u 7 29 Acute acute JJ cord-296469-h0ma163u 7 30 Respiratory Respiratory NNP cord-296469-h0ma163u 7 31 Syndrome Syndrome NNP cord-296469-h0ma163u 7 32 ( ( -LRB- cord-296469-h0ma163u 7 33 SARS SARS NNP cord-296469-h0ma163u 7 34 ) ) -RRB- cord-296469-h0ma163u 7 35 . . . cord-296469-h0ma163u 8 1 The the DT cord-296469-h0ma163u 8 2 cadence cadence NN cord-296469-h0ma163u 8 3 of of IN cord-296469-h0ma163u 8 4 emerging emerge VBG cord-296469-h0ma163u 8 5 infectious infectious JJ cord-296469-h0ma163u 8 6 diseases disease NNS cord-296469-h0ma163u 8 7 that that WDT cord-296469-h0ma163u 8 8 travel travel VBP cord-296469-h0ma163u 8 9 , , , cord-296469-h0ma163u 8 10 transmit transmit VB cord-296469-h0ma163u 8 11 and and CC cord-296469-h0ma163u 8 12 stand stand VB cord-296469-h0ma163u 8 13 ready ready JJ cord-296469-h0ma163u 8 14 to to TO cord-296469-h0ma163u 8 15 spark spark VB cord-296469-h0ma163u 8 16 a a DT cord-296469-h0ma163u 8 17 public public JJ cord-296469-h0ma163u 8 18 health health NN cord-296469-h0ma163u 8 19 emergency emergency NN cord-296469-h0ma163u 8 20 of of IN cord-296469-h0ma163u 8 21 international international JJ cord-296469-h0ma163u 8 22 concern concern NN cord-296469-h0ma163u 8 23 seems seem VBZ cord-296469-h0ma163u 8 24 to to TO cord-296469-h0ma163u 8 25 be be VB cord-296469-h0ma163u 8 26 accelerating accelerate VBG cord-296469-h0ma163u 8 27 . . . cord-296469-h0ma163u 9 1 These these DT cord-296469-h0ma163u 9 2 infectious infectious JJ cord-296469-h0ma163u 9 3 diseases disease NNS cord-296469-h0ma163u 9 4 cause cause VBP cord-296469-h0ma163u 9 5 significant significant JJ cord-296469-h0ma163u 9 6 human human JJ cord-296469-h0ma163u 9 7 suffering suffering NN cord-296469-h0ma163u 9 8 , , , cord-296469-h0ma163u 9 9 can can MD cord-296469-h0ma163u 9 10 overwhelm overwhelm VB cord-296469-h0ma163u 9 11 unprepared unprepared JJ cord-296469-h0ma163u 9 12 health health NN cord-296469-h0ma163u 9 13 care care NN cord-296469-h0ma163u 9 14 systems system NNS cord-296469-h0ma163u 9 15 , , , cord-296469-h0ma163u 9 16 and and CC cord-296469-h0ma163u 9 17 significantly significantly RB cord-296469-h0ma163u 9 18 disrupt disrupt VBP cord-296469-h0ma163u 9 19 societies society NNS cord-296469-h0ma163u 9 20 and and CC cord-296469-h0ma163u 9 21 economies economy NNS cord-296469-h0ma163u 9 22 . . . cord-296469-h0ma163u 10 1 It -PRON- PRP cord-296469-h0ma163u 10 2 is be VBZ cord-296469-h0ma163u 10 3 estimated estimate VBN cord-296469-h0ma163u 10 4 that that IN cord-296469-h0ma163u 10 5 a a DT cord-296469-h0ma163u 10 6 severe severe JJ cord-296469-h0ma163u 10 7 pandemic pandemic NN cord-296469-h0ma163u 10 8 similar similar JJ cord-296469-h0ma163u 10 9 to to IN cord-296469-h0ma163u 10 10 the the DT cord-296469-h0ma163u 10 11 1918 1918 CD cord-296469-h0ma163u 10 12 ' ' POS cord-296469-h0ma163u 10 13 ' ' `` cord-296469-h0ma163u 10 14 Spanish spanish JJ cord-296469-h0ma163u 10 15 flu flu NN cord-296469-h0ma163u 10 16 " " '' cord-296469-h0ma163u 10 17 could could MD cord-296469-h0ma163u 10 18 nowadays nowadays RB cord-296469-h0ma163u 10 19 cost cost VB cord-296469-h0ma163u 10 20 as as RB cord-296469-h0ma163u 10 21 much much JJ cord-296469-h0ma163u 10 22 as as IN cord-296469-h0ma163u 10 23 5 5 CD cord-296469-h0ma163u 10 24 % % NN cord-296469-h0ma163u 10 25 of of IN cord-296469-h0ma163u 10 26 global global JJ cord-296469-h0ma163u 10 27 gross gross JJ cord-296469-h0ma163u 10 28 domestic domestic JJ cord-296469-h0ma163u 10 29 product product NN cord-296469-h0ma163u 10 30 ; ; : cord-296469-h0ma163u 10 31 the the DT cord-296469-h0ma163u 10 32 global global JJ cord-296469-h0ma163u 10 33 cost cost NN cord-296469-h0ma163u 10 34 of of IN cord-296469-h0ma163u 10 35 even even RB cord-296469-h0ma163u 10 36 a a DT cord-296469-h0ma163u 10 37 moderately moderately RB cord-296469-h0ma163u 10 38 severe severe JJ cord-296469-h0ma163u 10 39 pandemic pandemic NN cord-296469-h0ma163u 10 40 could could MD cord-296469-h0ma163u 10 41 be be VB cord-296469-h0ma163u 10 42 as as RB cord-296469-h0ma163u 10 43 much much JJ cord-296469-h0ma163u 10 44 as as IN cord-296469-h0ma163u 10 45 US$ us$ $ cord-296469-h0ma163u 10 46 570 570 CD cord-296469-h0ma163u 10 47 billion billion CD cord-296469-h0ma163u 10 48 , , , cord-296469-h0ma163u 10 49 or or CC cord-296469-h0ma163u 10 50 0.7 0.7 CD cord-296469-h0ma163u 10 51 % % NN cord-296469-h0ma163u 10 52 of of IN cord-296469-h0ma163u 10 53 global global JJ cord-296469-h0ma163u 10 54 income income NN cord-296469-h0ma163u 10 55 [ [ -LRB- cord-296469-h0ma163u 10 56 1 1 CD cord-296469-h0ma163u 10 57 ] ] -RRB- cord-296469-h0ma163u 10 58 . . . cord-296469-h0ma163u 11 1 Given give VBN cord-296469-h0ma163u 11 2 the the DT cord-296469-h0ma163u 11 3 health health NN cord-296469-h0ma163u 11 4 , , , cord-296469-h0ma163u 11 5 social social JJ cord-296469-h0ma163u 11 6 and and CC cord-296469-h0ma163u 11 7 economic economic JJ cord-296469-h0ma163u 11 8 impact impact NN cord-296469-h0ma163u 11 9 of of IN cord-296469-h0ma163u 11 10 infectious infectious JJ cord-296469-h0ma163u 11 11 diseases disease NNS cord-296469-h0ma163u 11 12 with with IN cord-296469-h0ma163u 11 13 pandemic pandemic NN cord-296469-h0ma163u 11 14 potential potential NN cord-296469-h0ma163u 11 15 , , , cord-296469-h0ma163u 11 16 there there EX cord-296469-h0ma163u 11 17 has have VBZ cord-296469-h0ma163u 11 18 been be VBN cord-296469-h0ma163u 11 19 much much JJ cord-296469-h0ma163u 11 20 attention attention NN cord-296469-h0ma163u 11 21 to to IN cord-296469-h0ma163u 11 22 these these DT cord-296469-h0ma163u 11 23 microbial microbial JJ cord-296469-h0ma163u 11 24 threats threat NNS cord-296469-h0ma163u 11 25 and and CC cord-296469-h0ma163u 11 26 , , , cord-296469-h0ma163u 11 27 not not RB cord-296469-h0ma163u 11 28 surprisingly surprisingly RB cord-296469-h0ma163u 11 29 , , , cord-296469-h0ma163u 11 30 the the DT cord-296469-h0ma163u 11 31 first first JJ cord-296469-h0ma163u 11 32 question question NN cord-296469-h0ma163u 11 33 is be VBZ cord-296469-h0ma163u 11 34 always always RB cord-296469-h0ma163u 11 35 , , , cord-296469-h0ma163u 11 36 ' ' '' cord-296469-h0ma163u 11 37 ' ' '' cord-296469-h0ma163u 11 38 Is be VBZ cord-296469-h0ma163u 11 39 there there EX cord-296469-h0ma163u 11 40 a a DT cord-296469-h0ma163u 11 41 vaccine vaccine NN cord-296469-h0ma163u 11 42 ? ? . cord-296469-h0ma163u 12 1 " " '' cord-296469-h0ma163u 13 1 But but CC cord-296469-h0ma163u 13 2 too too RB cord-296469-h0ma163u 13 3 often often RB cord-296469-h0ma163u 13 4 we -PRON- PRP cord-296469-h0ma163u 13 5 find find VBP cord-296469-h0ma163u 13 6 that that IN cord-296469-h0ma163u 13 7 the the DT cord-296469-h0ma163u 13 8 vaccines vaccine NNS cord-296469-h0ma163u 13 9 we -PRON- PRP cord-296469-h0ma163u 13 10 need need VBP cord-296469-h0ma163u 13 11 most most JJS cord-296469-h0ma163u 13 12 are be VBP cord-296469-h0ma163u 13 13 not not RB cord-296469-h0ma163u 13 14 available available JJ cord-296469-h0ma163u 13 15 when when WRB cord-296469-h0ma163u 13 16 we -PRON- PRP cord-296469-h0ma163u 13 17 need need VBP cord-296469-h0ma163u 13 18 them -PRON- PRP cord-296469-h0ma163u 13 19 most most RBS cord-296469-h0ma163u 13 20 . . . cord-296469-h0ma163u 14 1 A a DT cord-296469-h0ma163u 14 2 number number NN cord-296469-h0ma163u 14 3 of of IN cord-296469-h0ma163u 14 4 efforts effort NNS cord-296469-h0ma163u 14 5 are be VBP cord-296469-h0ma163u 14 6 focused focus VBN cord-296469-h0ma163u 14 7 on on IN cord-296469-h0ma163u 14 8 better well RBR cord-296469-h0ma163u 14 9 anticipating anticipate VBG cord-296469-h0ma163u 14 10 the the DT cord-296469-h0ma163u 14 11 vaccines vaccine NNS cord-296469-h0ma163u 14 12 that that WDT cord-296469-h0ma163u 14 13 we -PRON- PRP cord-296469-h0ma163u 14 14 may may MD cord-296469-h0ma163u 14 15 need need VB cord-296469-h0ma163u 14 16 [ [ -LRB- cord-296469-h0ma163u 14 17 2 2 CD cord-296469-h0ma163u 14 18 ] ] -RRB- cord-296469-h0ma163u 14 19 [ [ -LRB- cord-296469-h0ma163u 14 20 3 3 CD cord-296469-h0ma163u 14 21 ] ] -RRB- cord-296469-h0ma163u 14 22 [ [ -LRB- cord-296469-h0ma163u 14 23 4 4 CD cord-296469-h0ma163u 14 24 ] ] -RRB- cord-296469-h0ma163u 14 25 [ [ -LRB- cord-296469-h0ma163u 14 26 5 5 CD cord-296469-h0ma163u 14 27 ] ] -RRB- cord-296469-h0ma163u 14 28 [ [ -LRB- cord-296469-h0ma163u 14 29 6 6 CD cord-296469-h0ma163u 14 30 ] ] -RRB- cord-296469-h0ma163u 14 31 and and CC cord-296469-h0ma163u 14 32 a a DT cord-296469-h0ma163u 14 33 global global JJ cord-296469-h0ma163u 14 34 emergency emergency NN cord-296469-h0ma163u 14 35 fund fund NN cord-296469-h0ma163u 14 36 has have VBZ cord-296469-h0ma163u 14 37 been be VBN cord-296469-h0ma163u 14 38 proposed propose VBN cord-296469-h0ma163u 14 39 to to TO cord-296469-h0ma163u 14 40 support support VB cord-296469-h0ma163u 14 41 accelerated accelerated JJ cord-296469-h0ma163u 14 42 vaccine vaccine NN cord-296469-h0ma163u 14 43 development development NN cord-296469-h0ma163u 14 44 [ [ -LRB- cord-296469-h0ma163u 14 45 7 7 CD cord-296469-h0ma163u 14 46 ] ] -RRB- cord-296469-h0ma163u 14 47 . . . cord-296469-h0ma163u 15 1 The the DT cord-296469-h0ma163u 15 2 current current JJ cord-296469-h0ma163u 15 3 headlines headline NNS cord-296469-h0ma163u 15 4 about about IN cord-296469-h0ma163u 15 5 Zika Zika NNP cord-296469-h0ma163u 15 6 virus virus NN cord-296469-h0ma163u 15 7 have have VBP cord-296469-h0ma163u 15 8 replaced replace VBN cord-296469-h0ma163u 15 9 last last JJ cord-296469-h0ma163u 15 10 year year NN cord-296469-h0ma163u 15 11 's 's POS cord-296469-h0ma163u 15 12 headlines headline NNS cord-296469-h0ma163u 15 13 about about IN cord-296469-h0ma163u 15 14 Ebola Ebola NNP cord-296469-h0ma163u 15 15 . . . cord-296469-h0ma163u 15 16 . . . cord-296469-h0ma163u 16 1 .and .and . cord-296469-h0ma163u 17 1 next next JJ cord-296469-h0ma163u 17 2 year year NN cord-296469-h0ma163u 17 3 's 's POS cord-296469-h0ma163u 17 4 headlines headline NNS cord-296469-h0ma163u 17 5 will will MD cord-296469-h0ma163u 17 6 undoubtedly undoubtedly RB cord-296469-h0ma163u 17 7 feature feature VB cord-296469-h0ma163u 17 8 something something NN cord-296469-h0ma163u 17 9 new new JJ cord-296469-h0ma163u 17 10 . . . cord-296469-h0ma163u 18 1 Imperfect imperfect JJ cord-296469-h0ma163u 18 2 crystal crystal NN cord-296469-h0ma163u 18 3 balls ball NNS cord-296469-h0ma163u 18 4 fail fail VBP cord-296469-h0ma163u 18 5 to to TO cord-296469-h0ma163u 18 6 guide guide VB cord-296469-h0ma163u 18 7 us -PRON- PRP cord-296469-h0ma163u 18 8 with with IN cord-296469-h0ma163u 18 9 certainty certainty NN cord-296469-h0ma163u 18 10 . . . cord-296469-h0ma163u 19 1 But but CC cord-296469-h0ma163u 19 2 looming loom VBG cord-296469-h0ma163u 19 3 in in IN cord-296469-h0ma163u 19 4 the the DT cord-296469-h0ma163u 19 5 background background NN cord-296469-h0ma163u 19 6 is be VBZ cord-296469-h0ma163u 19 7 the the DT cord-296469-h0ma163u 19 8 ever ever RB cord-296469-h0ma163u 19 9 present present JJ cord-296469-h0ma163u 19 10 threat threat NN cord-296469-h0ma163u 19 11 of of IN cord-296469-h0ma163u 19 12 influenza influenza NN cord-296469-h0ma163u 19 13 , , , cord-296469-h0ma163u 19 14 the the DT cord-296469-h0ma163u 19 15 only only JJ cord-296469-h0ma163u 19 16 microbe microbe NN cord-296469-h0ma163u 19 17 that that WDT cord-296469-h0ma163u 19 18 causes cause VBZ cord-296469-h0ma163u 19 19 regular regular JJ cord-296469-h0ma163u 19 20 widespread widespread JJ cord-296469-h0ma163u 19 21 epidemics epidemic NNS cord-296469-h0ma163u 19 22 around around IN cord-296469-h0ma163u 19 23 the the DT cord-296469-h0ma163u 19 24 world world NN cord-296469-h0ma163u 19 25 . . . cord-296469-h0ma163u 20 1 Not not RB cord-296469-h0ma163u 20 2 so so RB cord-296469-h0ma163u 20 3 exotic exotic JJ cord-296469-h0ma163u 20 4 and and CC cord-296469-h0ma163u 20 5 all all RB cord-296469-h0ma163u 20 6 too too RB cord-296469-h0ma163u 20 7 familiar familiar JJ cord-296469-h0ma163u 21 1 -casually -casually : cord-296469-h0ma163u 21 2 referred refer VBN cord-296469-h0ma163u 21 3 to to IN cord-296469-h0ma163u 21 4 as as IN cord-296469-h0ma163u 22 1 the the DT cord-296469-h0ma163u 22 2 ' ' `` cord-296469-h0ma163u 22 3 ' ' `` cord-296469-h0ma163u 22 4 flu flu NN cord-296469-h0ma163u 22 5 " " '' cord-296469-h0ma163u 22 6 -influenza -influenza NN cord-296469-h0ma163u 22 7 is be VBZ cord-296469-h0ma163u 22 8 the the DT cord-296469-h0ma163u 22 9 virologist virologist NN cord-296469-h0ma163u 22 10 's 's POS cord-296469-h0ma163u 22 11 Trojan Trojan NNP cord-296469-h0ma163u 22 12 horse horse NN cord-296469-h0ma163u 22 13 , , , cord-296469-h0ma163u 22 14 as as IN cord-296469-h0ma163u 22 15 it -PRON- PRP cord-296469-h0ma163u 22 16 readily readily RB cord-296469-h0ma163u 22 17 and and CC cord-296469-h0ma163u 22 18 rapidly rapidly RB cord-296469-h0ma163u 22 19 mutates mutate VBZ cord-296469-h0ma163u 22 20 ( ( -LRB- cord-296469-h0ma163u 22 21 drift drift NN cord-296469-h0ma163u 22 22 ) ) -RRB- cord-296469-h0ma163u 22 23 , , , cord-296469-h0ma163u 22 24 has have VBZ cord-296469-h0ma163u 22 25 the the DT cord-296469-h0ma163u 22 26 ability ability NN cord-296469-h0ma163u 22 27 to to TO cord-296469-h0ma163u 22 28 swap swap VB cord-296469-h0ma163u 22 29 genetic genetic JJ cord-296469-h0ma163u 22 30 elements element NNS cord-296469-h0ma163u 22 31 from from IN cord-296469-h0ma163u 22 32 influenza influenza NN cord-296469-h0ma163u 22 33 viruses virus NNS cord-296469-h0ma163u 22 34 with with IN cord-296469-h0ma163u 22 35 origins origin NNS cord-296469-h0ma163u 22 36 in in IN cord-296469-h0ma163u 22 37 other other JJ cord-296469-h0ma163u 22 38 species specie NNS cord-296469-h0ma163u 22 39 ( ( -LRB- cord-296469-h0ma163u 22 40 shift shift NN cord-296469-h0ma163u 22 41 ) ) -RRB- cord-296469-h0ma163u 22 42 and and CC cord-296469-h0ma163u 22 43 , , , cord-296469-h0ma163u 22 44 as as IN cord-296469-h0ma163u 22 45 an an DT cord-296469-h0ma163u 22 46 RNA RNA NNP cord-296469-h0ma163u 22 47 virus virus NN cord-296469-h0ma163u 22 48 lacks lack VBZ cord-296469-h0ma163u 22 49 repair repair NN cord-296469-h0ma163u 22 50 and and CC cord-296469-h0ma163u 22 51 self self NN cord-296469-h0ma163u 22 52 - - HYPH cord-296469-h0ma163u 22 53 correcting correct VBG cord-296469-h0ma163u 22 54 mechanisms mechanism NNS cord-296469-h0ma163u 22 55 that that WDT cord-296469-h0ma163u 22 56 are be VBP cord-296469-h0ma163u 22 57 the the DT cord-296469-h0ma163u 22 58 basis basis NN cord-296469-h0ma163u 22 59 of of IN cord-296469-h0ma163u 22 60 its -PRON- PRP$ cord-296469-h0ma163u 22 61 genetic genetic JJ cord-296469-h0ma163u 22 62 instability instability NN cord-296469-h0ma163u 22 63 and and CC cord-296469-h0ma163u 22 64 makes make VBZ cord-296469-h0ma163u 22 65 it -PRON- PRP cord-296469-h0ma163u 22 66 both both CC cord-296469-h0ma163u 22 67 dangerous dangerous JJ cord-296469-h0ma163u 22 68 and and CC cord-296469-h0ma163u 22 69 unpredictable unpredictable JJ cord-296469-h0ma163u 22 70 . . . cord-296469-h0ma163u 23 1 A a DT cord-296469-h0ma163u 23 2 reassortment reassortment NN cord-296469-h0ma163u 23 3 leading lead VBG cord-296469-h0ma163u 23 4 to to IN cord-296469-h0ma163u 23 5 an an DT cord-296469-h0ma163u 23 6 extremely extremely RB cord-296469-h0ma163u 23 7 virulent virulent JJ cord-296469-h0ma163u 23 8 and and CC cord-296469-h0ma163u 23 9 readily readily RB cord-296469-h0ma163u 23 10 transmissible transmissible JJ cord-296469-h0ma163u 23 11 pandemic pandemic NN cord-296469-h0ma163u 23 12 virus virus NN cord-296469-h0ma163u 23 13 is be VBZ cord-296469-h0ma163u 23 14 inevitable inevitable JJ cord-296469-h0ma163u 23 15 . . . cord-296469-h0ma163u 24 1 Of of IN cord-296469-h0ma163u 24 2 the the DT cord-296469-h0ma163u 24 3 many many JJ cord-296469-h0ma163u 24 4 things thing NNS cord-296469-h0ma163u 24 5 that that WDT cord-296469-h0ma163u 24 6 need need VBP cord-296469-h0ma163u 24 7 to to TO cord-296469-h0ma163u 24 8 be be VB cord-296469-h0ma163u 24 9 in in IN cord-296469-h0ma163u 24 10 place place NN cord-296469-h0ma163u 24 11 to to TO cord-296469-h0ma163u 24 12 prepare prepare VB cord-296469-h0ma163u 24 13 for for IN cord-296469-h0ma163u 24 14 and and CC cord-296469-h0ma163u 24 15 respond respond VB cord-296469-h0ma163u 24 16 to to IN cord-296469-h0ma163u 24 17 the the DT cord-296469-h0ma163u 24 18 next next JJ cord-296469-h0ma163u 24 19 influenza influenza NN cord-296469-h0ma163u 24 20 pandemic pandemic NN cord-296469-h0ma163u 24 21 , , , cord-296469-h0ma163u 24 22 vaccines vaccine NNS cord-296469-h0ma163u 24 23 -together -together : cord-296469-h0ma163u 24 24 with with IN cord-296469-h0ma163u 24 25 the the DT cord-296469-h0ma163u 24 26 capacity capacity NN cord-296469-h0ma163u 24 27 to to TO cord-296469-h0ma163u 24 28 mount mount VB cord-296469-h0ma163u 24 29 a a DT cord-296469-h0ma163u 24 30 timely timely RB cord-296469-h0ma163u 24 31 global global JJ cord-296469-h0ma163u 24 32 vaccination vaccination NN cord-296469-h0ma163u 24 33 effort effort NN cord-296469-h0ma163u 24 34 -are -are : cord-296469-h0ma163u 24 35 paramount paramount NN cord-296469-h0ma163u 24 36 . . . cord-296469-h0ma163u 25 1 A a DT cord-296469-h0ma163u 25 2 pandemic pandemic NN cord-296469-h0ma163u 25 3 can can MD cord-296469-h0ma163u 25 4 only only RB cord-296469-h0ma163u 25 5 be be VB cord-296469-h0ma163u 25 6 brought bring VBN cord-296469-h0ma163u 25 7 under under IN cord-296469-h0ma163u 25 8 control control NN cord-296469-h0ma163u 25 9 through through IN cord-296469-h0ma163u 25 10 a a DT cord-296469-h0ma163u 25 11 shift shift NN cord-296469-h0ma163u 25 12 in in IN cord-296469-h0ma163u 25 13 the the DT cord-296469-h0ma163u 25 14 population population NN cord-296469-h0ma163u 25 15 from from IN cord-296469-h0ma163u 25 16 susceptibility susceptibility NN cord-296469-h0ma163u 25 17 to to IN cord-296469-h0ma163u 25 18 immunity immunity NN cord-296469-h0ma163u 25 19 . . . cord-296469-h0ma163u 26 1 But but CC cord-296469-h0ma163u 26 2 as as IN cord-296469-h0ma163u 26 3 we -PRON- PRP cord-296469-h0ma163u 26 4 learned learn VBD cord-296469-h0ma163u 26 5 in in IN cord-296469-h0ma163u 26 6 the the DT cord-296469-h0ma163u 26 7 2009 2009 CD cord-296469-h0ma163u 26 8 influenza influenza NN cord-296469-h0ma163u 26 9 pandemic pandemic NN cord-296469-h0ma163u 26 10 , , , cord-296469-h0ma163u 26 11 although although IN cord-296469-h0ma163u 26 12 our -PRON- PRP$ cord-296469-h0ma163u 26 13 response response NN cord-296469-h0ma163u 26 14 time time NN cord-296469-h0ma163u 26 15 has have VBZ cord-296469-h0ma163u 26 16 improved improve VBN cord-296469-h0ma163u 26 17 , , , cord-296469-h0ma163u 26 18 a a DT cord-296469-h0ma163u 26 19 significant significant JJ cord-296469-h0ma163u 26 20 shift shift NN cord-296469-h0ma163u 26 21 in in IN cord-296469-h0ma163u 26 22 approach approach NN cord-296469-h0ma163u 26 23 is be VBZ cord-296469-h0ma163u 26 24 needed need VBN cord-296469-h0ma163u 26 25 if if IN cord-296469-h0ma163u 26 26 an an DT cord-296469-h0ma163u 26 27 effective effective JJ cord-296469-h0ma163u 26 28 vaccine vaccine NN cord-296469-h0ma163u 26 29 is be VBZ cord-296469-h0ma163u 26 30 to to TO cord-296469-h0ma163u 26 31 be be VB cord-296469-h0ma163u 26 32 in in IN cord-296469-h0ma163u 26 33 place place NN cord-296469-h0ma163u 26 34 before before IN cord-296469-h0ma163u 26 35 the the DT cord-296469-h0ma163u 26 36 next next JJ cord-296469-h0ma163u 26 37 pandemic pandemic NN cord-296469-h0ma163u 26 38 emerges emerge VBZ cord-296469-h0ma163u 26 39 . . . cord-296469-h0ma163u 27 1 With with IN cord-296469-h0ma163u 27 2 that that DT cord-296469-h0ma163u 27 3 goal goal NN cord-296469-h0ma163u 27 4 in in IN cord-296469-h0ma163u 27 5 mind mind NN cord-296469-h0ma163u 27 6 , , , cord-296469-h0ma163u 27 7 the the DT cord-296469-h0ma163u 27 8 science science NN cord-296469-h0ma163u 27 9 of of IN cord-296469-h0ma163u 27 10 influenza influenza NN cord-296469-h0ma163u 27 11 and and CC cord-296469-h0ma163u 27 12 of of IN cord-296469-h0ma163u 27 13 vaccine vaccine NN cord-296469-h0ma163u 27 14 development development NN cord-296469-h0ma163u 27 15 needs need VBZ cord-296469-h0ma163u 27 16 to to TO cord-296469-h0ma163u 27 17 be be VB cord-296469-h0ma163u 27 18 looked look VBN cord-296469-h0ma163u 27 19 at at IN cord-296469-h0ma163u 27 20 with with IN cord-296469-h0ma163u 27 21 fresh fresh JJ cord-296469-h0ma163u 27 22 eyes eye NNS cord-296469-h0ma163u 27 23 [ [ -LRB- cord-296469-h0ma163u 27 24 8 8 CD cord-296469-h0ma163u 27 25 ] ] -RRB- cord-296469-h0ma163u 27 26 . . . cord-296469-h0ma163u 28 1 The the DT cord-296469-h0ma163u 28 2 Holy Holy NNP cord-296469-h0ma163u 28 3 Grail Grail NNP cord-296469-h0ma163u 28 4 is be VBZ cord-296469-h0ma163u 28 5 an an DT cord-296469-h0ma163u 28 6 influenza influenza NN cord-296469-h0ma163u 28 7 vaccine vaccine NN cord-296469-h0ma163u 28 8 that that WDT cord-296469-h0ma163u 28 9 provides provide VBZ cord-296469-h0ma163u 28 10 a a DT cord-296469-h0ma163u 28 11 broader broad JJR cord-296469-h0ma163u 28 12 and and CC cord-296469-h0ma163u 28 13 more more RBR cord-296469-h0ma163u 28 14 durable durable JJ cord-296469-h0ma163u 28 15 immune immune JJ cord-296469-h0ma163u 28 16 response response NN cord-296469-h0ma163u 28 17 than than IN cord-296469-h0ma163u 28 18 the the DT cord-296469-h0ma163u 28 19 natural natural JJ cord-296469-h0ma163u 28 20 infection infection NN cord-296469-h0ma163u 28 21 and and CC cord-296469-h0ma163u 28 22 that that WDT cord-296469-h0ma163u 28 23 can can MD cord-296469-h0ma163u 28 24 provide provide VB cord-296469-h0ma163u 28 25 population population NN cord-296469-h0ma163u 28 26 immunity immunity NN cord-296469-h0ma163u 28 27 to to IN cord-296469-h0ma163u 28 28 pandemic pandemic NN cord-296469-h0ma163u 28 29 influenza influenza NN cord-296469-h0ma163u 28 30 viruses virus NNS cord-296469-h0ma163u 28 31 before before IN cord-296469-h0ma163u 28 32 they -PRON- PRP cord-296469-h0ma163u 28 33 emerge emerge VBP cord-296469-h0ma163u 28 34 . . . cord-296469-h0ma163u 29 1 A a DT cord-296469-h0ma163u 29 2 number number NN cord-296469-h0ma163u 29 3 of of IN cord-296469-h0ma163u 29 4 efforts effort NNS cord-296469-h0ma163u 29 5 are be VBP cord-296469-h0ma163u 29 6 now now RB cord-296469-h0ma163u 29 7 focused focus VBN cord-296469-h0ma163u 29 8 on on IN cord-296469-h0ma163u 29 9 developing develop VBG cord-296469-h0ma163u 29 10 such such PDT cord-296469-h0ma163u 29 11 a a DT cord-296469-h0ma163u 29 12 ' ' `` cord-296469-h0ma163u 29 13 ' ' `` cord-296469-h0ma163u 29 14 universal universal JJ cord-296469-h0ma163u 29 15 " " '' cord-296469-h0ma163u 29 16 influenza influenza NN cord-296469-h0ma163u 29 17 vaccine vaccine NN cord-296469-h0ma163u 29 18 ; ; : cord-296469-h0ma163u 29 19 however however RB cord-296469-h0ma163u 29 20 , , , cord-296469-h0ma163u 29 21 the the DT cord-296469-h0ma163u 29 22 scientific scientific JJ cord-296469-h0ma163u 29 23 challenges challenge NNS cord-296469-h0ma163u 29 24 involved involve VBN cord-296469-h0ma163u 29 25 are be VBP cord-296469-h0ma163u 29 26 enormous enormous JJ cord-296469-h0ma163u 29 27 [ [ -LRB- cord-296469-h0ma163u 29 28 9 9 CD cord-296469-h0ma163u 29 29 , , , cord-296469-h0ma163u 29 30 10 10 CD cord-296469-h0ma163u 29 31 ] ] -RRB- cord-296469-h0ma163u 29 32 . . . cord-296469-h0ma163u 30 1 Until until IN cord-296469-h0ma163u 30 2 such such PDT cord-296469-h0ma163u 30 3 a a DT cord-296469-h0ma163u 30 4 universal universal JJ cord-296469-h0ma163u 30 5 influenza influenza NN cord-296469-h0ma163u 30 6 vaccine vaccine NN cord-296469-h0ma163u 30 7 becomes become VBZ cord-296469-h0ma163u 30 8 available available JJ cord-296469-h0ma163u 30 9 , , , cord-296469-h0ma163u 30 10 global global JJ cord-296469-h0ma163u 30 11 influenza influenza NN cord-296469-h0ma163u 30 12 vaccine vaccine NN cord-296469-h0ma163u 30 13 production production NN cord-296469-h0ma163u 30 14 capacity capacity NN cord-296469-h0ma163u 30 15 needs need VBZ cord-296469-h0ma163u 30 16 to to TO cord-296469-h0ma163u 30 17 be be VB cord-296469-h0ma163u 30 18 ready ready JJ cord-296469-h0ma163u 30 19 to to TO cord-296469-h0ma163u 30 20 respond respond VB cord-296469-h0ma163u 30 21 when when WRB cord-296469-h0ma163u 30 22 the the DT cord-296469-h0ma163u 30 23 next next JJ cord-296469-h0ma163u 30 24 pandemic pandemic NN cord-296469-h0ma163u 30 25 emerges emerge VBZ cord-296469-h0ma163u 30 26 . . . cord-296469-h0ma163u 31 1 Vaccines vaccine NNS cord-296469-h0ma163u 31 2 obviously obviously RB cord-296469-h0ma163u 31 3 need need VBP cord-296469-h0ma163u 31 4 to to TO cord-296469-h0ma163u 31 5 be be VB cord-296469-h0ma163u 31 6 safe safe JJ cord-296469-h0ma163u 31 7 and and CC cord-296469-h0ma163u 31 8 effective effective JJ cord-296469-h0ma163u 31 9 , , , cord-296469-h0ma163u 31 10 but but CC cord-296469-h0ma163u 31 11 they -PRON- PRP cord-296469-h0ma163u 31 12 must must MD cord-296469-h0ma163u 31 13 also also RB cord-296469-h0ma163u 31 14 be be VB cord-296469-h0ma163u 31 15 available available JJ cord-296469-h0ma163u 31 16 and and CC cord-296469-h0ma163u 31 17 affordable affordable JJ cord-296469-h0ma163u 31 18 . . . cord-296469-h0ma163u 32 1 While while IN cord-296469-h0ma163u 32 2 vaccine vaccine NN cord-296469-h0ma163u 32 3 supply supply NN cord-296469-h0ma163u 32 4 is be VBZ cord-296469-h0ma163u 32 5 clearly clearly RB cord-296469-h0ma163u 32 6 essential essential JJ cord-296469-h0ma163u 32 7 for for IN cord-296469-h0ma163u 32 8 a a DT cord-296469-h0ma163u 32 9 large large JJ cord-296469-h0ma163u 32 10 - - HYPH cord-296469-h0ma163u 32 11 scale scale NN cord-296469-h0ma163u 32 12 vaccination vaccination NN cord-296469-h0ma163u 32 13 programme programme NN cord-296469-h0ma163u 32 14 , , , cord-296469-h0ma163u 32 15 the the DT cord-296469-h0ma163u 32 16 logistics logistic NNS cord-296469-h0ma163u 32 17 and and CC cord-296469-h0ma163u 32 18 supporting support VBG cord-296469-h0ma163u 32 19 policies policy NNS cord-296469-h0ma163u 32 20 needed need VBN cord-296469-h0ma163u 32 21 to to TO cord-296469-h0ma163u 32 22 conduct conduct VB cord-296469-h0ma163u 32 23 effective effective JJ cord-296469-h0ma163u 32 24 and and CC cord-296469-h0ma163u 32 25 efficient efficient JJ cord-296469-h0ma163u 32 26 vaccination vaccination NN cord-296469-h0ma163u 32 27 campaigns campaign NNS cord-296469-h0ma163u 32 28 in in IN cord-296469-h0ma163u 32 29 a a DT cord-296469-h0ma163u 32 30 range range NN cord-296469-h0ma163u 32 31 of of IN cord-296469-h0ma163u 32 32 community community NN cord-296469-h0ma163u 32 33 settings setting NNS cord-296469-h0ma163u 32 34 also also RB cord-296469-h0ma163u 32 35 need need VBP cord-296469-h0ma163u 32 36 to to TO cord-296469-h0ma163u 32 37 be be VB cord-296469-h0ma163u 32 38 addressed address VBN cord-296469-h0ma163u 32 39 and and CC cord-296469-h0ma163u 32 40 the the DT cord-296469-h0ma163u 32 41 needs need NNS cord-296469-h0ma163u 32 42 of of IN cord-296469-h0ma163u 32 43 high high JJ cord-296469-h0ma163u 32 44 - - HYPH cord-296469-h0ma163u 32 45 risk risk NN cord-296469-h0ma163u 32 46 and and CC cord-296469-h0ma163u 32 47 vulnerable vulnerable JJ cord-296469-h0ma163u 32 48 populations population NNS cord-296469-h0ma163u 32 49 and and CC cord-296469-h0ma163u 32 50 of of IN cord-296469-h0ma163u 32 51 low low JJ cord-296469-h0ma163u 32 52 - - HYPH cord-296469-h0ma163u 32 53 and and CC cord-296469-h0ma163u 32 54 middle middle JJ cord-296469-h0ma163u 32 55 - - HYPH cord-296469-h0ma163u 32 56 income income NN cord-296469-h0ma163u 32 57 countries country NNS cord-296469-h0ma163u 32 58 accommodated accommodate VBN cord-296469-h0ma163u 32 59 . . . cord-296469-h0ma163u 33 1 Ultimately ultimately RB cord-296469-h0ma163u 33 2 , , , cord-296469-h0ma163u 33 3 the the DT cord-296469-h0ma163u 33 4 success success NN cord-296469-h0ma163u 33 5 of of IN cord-296469-h0ma163u 33 6 a a DT cord-296469-h0ma163u 33 7 vaccination vaccination NN cord-296469-h0ma163u 33 8 programme programme NN cord-296469-h0ma163u 33 9 will will MD cord-296469-h0ma163u 33 10 hinge hinge VB cord-296469-h0ma163u 33 11 not not RB cord-296469-h0ma163u 33 12 only only RB cord-296469-h0ma163u 33 13 on on IN cord-296469-h0ma163u 33 14 the the DT cord-296469-h0ma163u 33 15 technical technical JJ cord-296469-h0ma163u 33 16 aspects aspect NNS cord-296469-h0ma163u 33 17 of of IN cord-296469-h0ma163u 33 18 its -PRON- PRP$ cord-296469-h0ma163u 33 19 implementation implementation NN cord-296469-h0ma163u 33 20 , , , cord-296469-h0ma163u 33 21 but but CC cord-296469-h0ma163u 33 22 on on IN cord-296469-h0ma163u 33 23 the the DT cord-296469-h0ma163u 33 24 demand demand NN cord-296469-h0ma163u 33 25 for for IN cord-296469-h0ma163u 33 26 it -PRON- PRP cord-296469-h0ma163u 33 27 among among IN cord-296469-h0ma163u 33 28 the the DT cord-296469-h0ma163u 33 29 population population NN cord-296469-h0ma163u 33 30 ; ; : cord-296469-h0ma163u 33 31 this this DT cord-296469-h0ma163u 33 32 underscores underscore VBZ cord-296469-h0ma163u 33 33 the the DT cord-296469-h0ma163u 33 34 need need NN cord-296469-h0ma163u 33 35 to to TO cord-296469-h0ma163u 33 36 understand understand VB cord-296469-h0ma163u 33 37 the the DT cord-296469-h0ma163u 33 38 factors factor NNS cord-296469-h0ma163u 33 39 that that WDT cord-296469-h0ma163u 33 40 promote promote VBP cord-296469-h0ma163u 33 41 vaccine vaccine NN cord-296469-h0ma163u 33 42 acceptance acceptance NN cord-296469-h0ma163u 33 43 [ [ -LRB- cord-296469-h0ma163u 33 44 11 11 CD cord-296469-h0ma163u 33 45 , , , cord-296469-h0ma163u 33 46 12 12 CD cord-296469-h0ma163u 33 47 ] ] -RRB- cord-296469-h0ma163u 33 48 . . . cord-296469-h0ma163u 34 1 Within within IN cord-296469-h0ma163u 34 2 this this DT cord-296469-h0ma163u 34 3 broad broad JJ cord-296469-h0ma163u 34 4 framework framework NN cord-296469-h0ma163u 34 5 , , , cord-296469-h0ma163u 34 6 and and CC cord-296469-h0ma163u 34 7 with with IN cord-296469-h0ma163u 34 8 a a DT cord-296469-h0ma163u 34 9 focus focus NN cord-296469-h0ma163u 34 10 on on IN cord-296469-h0ma163u 34 11 the the DT cord-296469-h0ma163u 34 12 role role NN cord-296469-h0ma163u 34 13 of of IN cord-296469-h0ma163u 34 14 vaccines vaccine NNS cord-296469-h0ma163u 34 15 in in IN cord-296469-h0ma163u 34 16 mitigating mitigate VBG cord-296469-h0ma163u 34 17 the the DT cord-296469-h0ma163u 34 18 impact impact NN cord-296469-h0ma163u 34 19 of of IN cord-296469-h0ma163u 34 20 both both DT cord-296469-h0ma163u 34 21 seasonal seasonal JJ cord-296469-h0ma163u 34 22 and and CC cord-296469-h0ma163u 34 23 pandemic pandemic NN cord-296469-h0ma163u 34 24 influenza influenza NN cord-296469-h0ma163u 34 25 , , , cord-296469-h0ma163u 34 26 WHO who WP cord-296469-h0ma163u 34 27 established establish VBD cord-296469-h0ma163u 34 28 in in IN cord-296469-h0ma163u 34 29 2006 2006 CD cord-296469-h0ma163u 34 30 the the DT cord-296469-h0ma163u 34 31 Global Global NNP cord-296469-h0ma163u 34 32 Action Action NNP cord-296469-h0ma163u 34 33 Plan Plan NNP cord-296469-h0ma163u 34 34 for for IN cord-296469-h0ma163u 34 35 Influenza Influenza NNP cord-296469-h0ma163u 34 36 Vaccines Vaccines NNPS cord-296469-h0ma163u 34 37 ( ( -LRB- cord-296469-h0ma163u 34 38 GAP GAP NNP cord-296469-h0ma163u 34 39 ) ) -RRB- cord-296469-h0ma163u 34 40 as as IN cord-296469-h0ma163u 34 41 ' ' `` cord-296469-h0ma163u 34 42 ' ' '' cord-296469-h0ma163u 34 43 a a DT cord-296469-h0ma163u 34 44 comprehensive comprehensive JJ cord-296469-h0ma163u 34 45 strategy strategy NN cord-296469-h0ma163u 34 46 to to TO cord-296469-h0ma163u 34 47 reduce reduce VB cord-296469-h0ma163u 34 48 the the DT cord-296469-h0ma163u 34 49 present present JJ cord-296469-h0ma163u 34 50 global global JJ cord-296469-h0ma163u 34 51 shortage shortage NN cord-296469-h0ma163u 34 52 of of IN cord-296469-h0ma163u 34 53 influenza influenza NN cord-296469-h0ma163u 34 54 vaccines vaccine NNS cord-296469-h0ma163u 34 55 for for IN cord-296469-h0ma163u 34 56 seasonal seasonal JJ cord-296469-h0ma163u 34 57 epidemics epidemic NNS cord-296469-h0ma163u 34 58 and and CC cord-296469-h0ma163u 34 59 pandemic pandemic NN cord-296469-h0ma163u 34 60 influenza influenza NN cord-296469-h0ma163u 34 61 in in IN cord-296469-h0ma163u 34 62 all all DT cord-296469-h0ma163u 34 63 countries country NNS cord-296469-h0ma163u 34 64 of of IN cord-296469-h0ma163u 34 65 the the DT cord-296469-h0ma163u 34 66 world world NN cord-296469-h0ma163u 34 67 " " '' cord-296469-h0ma163u 34 68 [ [ -LRB- cord-296469-h0ma163u 34 69 13 13 CD cord-296469-h0ma163u 34 70 ] ] -RRB- cord-296469-h0ma163u 34 71 . . . cord-296469-h0ma163u 35 1 The the DT cord-296469-h0ma163u 35 2 papers paper NNS cord-296469-h0ma163u 35 3 in in IN cord-296469-h0ma163u 35 4 this this DT cord-296469-h0ma163u 35 5 Special Special NNP cord-296469-h0ma163u 35 6 Issue Issue NNP cord-296469-h0ma163u 35 7 of of IN cord-296469-h0ma163u 35 8 Vaccine Vaccine NNP cord-296469-h0ma163u 35 9 , , , cord-296469-h0ma163u 35 10 provide provide VB cord-296469-h0ma163u 35 11 a a DT cord-296469-h0ma163u 35 12 foretaste foretaste NN cord-296469-h0ma163u 35 13 of of IN cord-296469-h0ma163u 35 14 the the DT cord-296469-h0ma163u 35 15 in in IN cord-296469-h0ma163u 35 16 - - HYPH cord-296469-h0ma163u 35 17 depth depth NN cord-296469-h0ma163u 35 18 review review NN cord-296469-h0ma163u 35 19 to to TO cord-296469-h0ma163u 35 20 come come VB cord-296469-h0ma163u 35 21 in in IN cord-296469-h0ma163u 35 22 November November NNP cord-296469-h0ma163u 35 23 2016 2016 CD cord-296469-h0ma163u 35 24 , , , cord-296469-h0ma163u 35 25 when when WRB cord-296469-h0ma163u 35 26 WHO who WP cord-296469-h0ma163u 35 27 will will MD cord-296469-h0ma163u 35 28 host host VB cord-296469-h0ma163u 35 29 the the DT cord-296469-h0ma163u 35 30 third third JJ cord-296469-h0ma163u 35 31 and and CC cord-296469-h0ma163u 35 32 final final JJ cord-296469-h0ma163u 35 33 consultation consultation NN cord-296469-h0ma163u 35 34 on on IN cord-296469-h0ma163u 35 35 GAP GAP NNP cord-296469-h0ma163u 35 36 as as IN cord-296469-h0ma163u 35 37 the the DT cord-296469-h0ma163u 35 38 programme programme NN cord-296469-h0ma163u 35 39 , , , cord-296469-h0ma163u 35 40 as as IN cord-296469-h0ma163u 35 41 it -PRON- PRP cord-296469-h0ma163u 35 42 exists exist VBZ cord-296469-h0ma163u 35 43 today today NN cord-296469-h0ma163u 35 44 , , , cord-296469-h0ma163u 35 45 comes come VBZ cord-296469-h0ma163u 35 46 to to TO cord-296469-h0ma163u 35 47 close close VB cord-296469-h0ma163u 35 48 . . . cord-296469-h0ma163u 36 1 The the DT cord-296469-h0ma163u 36 2 background background NN cord-296469-h0ma163u 36 3 papers paper NNS cord-296469-h0ma163u 36 4 prepared prepare VBN cord-296469-h0ma163u 36 5 for for IN cord-296469-h0ma163u 36 6 this this DT cord-296469-h0ma163u 36 7 consultation consultation NN cord-296469-h0ma163u 36 8 are be VBP cord-296469-h0ma163u 36 9 available available JJ cord-296469-h0ma163u 36 10 on on IN cord-296469-h0ma163u 36 11 the the DT cord-296469-h0ma163u 36 12 WHO WHO NNP cord-296469-h0ma163u 36 13 website website NN cord-296469-h0ma163u 36 14 ( ( -LRB- cord-296469-h0ma163u 36 15 http:// http:// NNP cord-296469-h0ma163u 36 16 www.who.int/influenza_vaccines_plan/news/gap3_Nov16/en/ www.who.int/influenza_vaccines_plan/news/gap3_Nov16/en/ NNP cord-296469-h0ma163u 36 17 ) ) -RRB- cord-296469-h0ma163u 36 18 . . . cord-296469-h0ma163u 37 1 While while IN cord-296469-h0ma163u 37 2 this this DT cord-296469-h0ma163u 37 3 event event NN cord-296469-h0ma163u 37 4 is be VBZ cord-296469-h0ma163u 37 5 advertised advertise VBN cord-296469-h0ma163u 37 6 as as IN cord-296469-h0ma163u 37 7 a a DT cord-296469-h0ma163u 37 8 programme programme NN cord-296469-h0ma163u 37 9 review review NN cord-296469-h0ma163u 37 10 , , , cord-296469-h0ma163u 37 11 in in IN cord-296469-h0ma163u 37 12 reality reality NN cord-296469-h0ma163u 37 13 as as IN cord-296469-h0ma163u 37 14 an an DT cord-296469-h0ma163u 37 15 examination examination NN cord-296469-h0ma163u 37 16 of of IN cord-296469-h0ma163u 37 17 the the DT cord-296469-h0ma163u 37 18 progress progress NN cord-296469-h0ma163u 37 19 achieved achieve VBN cord-296469-h0ma163u 37 20 during during IN cord-296469-h0ma163u 37 21 the the DT cord-296469-h0ma163u 37 22 decade decade NN cord-296469-h0ma163u 37 23 , , , cord-296469-h0ma163u 37 24 it -PRON- PRP cord-296469-h0ma163u 37 25 should should MD cord-296469-h0ma163u 37 26 also also RB cord-296469-h0ma163u 37 27 serve serve VB cord-296469-h0ma163u 37 28 to to TO cord-296469-h0ma163u 37 29 direct direct VB cord-296469-h0ma163u 37 30 the the DT cord-296469-h0ma163u 37 31 global global JJ cord-296469-h0ma163u 37 32 community community NN cord-296469-h0ma163u 37 33 on on IN cord-296469-h0ma163u 37 34 the the DT cord-296469-h0ma163u 37 35 path path NN cord-296469-h0ma163u 37 36 forward forward RB cord-296469-h0ma163u 37 37 for for IN cord-296469-h0ma163u 37 38 the the DT cord-296469-h0ma163u 37 39 work work NN cord-296469-h0ma163u 37 40 that that WDT cord-296469-h0ma163u 37 41 remains remain VBZ cord-296469-h0ma163u 37 42 to to TO cord-296469-h0ma163u 37 43 achieve achieve VB cord-296469-h0ma163u 37 44 global global JJ cord-296469-h0ma163u 37 45 pandemic pandemic NN cord-296469-h0ma163u 37 46 influenza influenza NN cord-296469-h0ma163u 37 47 vaccine vaccine NN cord-296469-h0ma163u 37 48 and and CC cord-296469-h0ma163u 37 49 vaccination vaccination NN cord-296469-h0ma163u 37 50 preparedness preparedness NN cord-296469-h0ma163u 37 51 . . . cord-296469-h0ma163u 38 1 This this DT cord-296469-h0ma163u 38 2 review review NN cord-296469-h0ma163u 38 3 , , , cord-296469-h0ma163u 38 4 combined combine VBN cord-296469-h0ma163u 38 5 with with IN cord-296469-h0ma163u 38 6 the the DT cord-296469-h0ma163u 38 7 current current JJ cord-296469-h0ma163u 38 8 rethinking rethinking NN cord-296469-h0ma163u 38 9 of of IN cord-296469-h0ma163u 38 10 global global JJ cord-296469-h0ma163u 38 11 preparedness preparedness NN cord-296469-h0ma163u 38 12 for for IN cord-296469-h0ma163u 38 13 emerging emerge VBG cord-296469-h0ma163u 38 14 threats threat NNS cord-296469-h0ma163u 38 15 , , , cord-296469-h0ma163u 38 16 the the DT cord-296469-h0ma163u 38 17 review review NN cord-296469-h0ma163u 38 18 of of IN cord-296469-h0ma163u 38 19 the the DT cord-296469-h0ma163u 38 20 Pandemic Pandemic NNP cord-296469-h0ma163u 38 21 Influenza Influenza NNP cord-296469-h0ma163u 38 22 Preparedness Preparedness NNP cord-296469-h0ma163u 38 23 ( ( -LRB- cord-296469-h0ma163u 38 24 PIP PIP NNP cord-296469-h0ma163u 38 25 ) ) -RRB- cord-296469-h0ma163u 38 26 Framework Framework NNP cord-296469-h0ma163u 38 27 [ [ -LRB- cord-296469-h0ma163u 38 28 14 14 CD cord-296469-h0ma163u 38 29 ] ] -RRB- cord-296469-h0ma163u 38 30 , , , cord-296469-h0ma163u 38 31 and and CC cord-296469-h0ma163u 38 32 WHO who WP cord-296469-h0ma163u 38 33 's be VBZ cord-296469-h0ma163u 38 34 restructuring restructuring NN cord-296469-h0ma163u 38 35 of of IN cord-296469-h0ma163u 38 36 its -PRON- PRP$ cord-296469-h0ma163u 38 37 approach approach NN cord-296469-h0ma163u 38 38 to to IN cord-296469-h0ma163u 38 39 global global JJ cord-296469-h0ma163u 38 40 health health NN cord-296469-h0ma163u 38 41 emergencies emergency NNS cord-296469-h0ma163u 39 1 The the DT cord-296469-h0ma163u 39 2 Global Global NNP cord-296469-h0ma163u 39 3 Action Action NNP cord-296469-h0ma163u 39 4 Plan Plan NNP cord-296469-h0ma163u 39 5 for for IN cord-296469-h0ma163u 39 6 Influenza Influenza NNP cord-296469-h0ma163u 39 7 Vaccines Vaccines NNPS cord-296469-h0ma163u 39 8 was be VBD cord-296469-h0ma163u 39 9 structured structure VBN cord-296469-h0ma163u 39 10 around around IN cord-296469-h0ma163u 39 11 three three CD cord-296469-h0ma163u 39 12 broad broad JJ cord-296469-h0ma163u 39 13 objectives objective NNS cord-296469-h0ma163u 39 14 that that WDT cord-296469-h0ma163u 39 15 underpin underpin VBP cord-296469-h0ma163u 39 16 pandemic pandemic NN cord-296469-h0ma163u 39 17 influenza influenza NN cord-296469-h0ma163u 39 18 vaccine vaccine NN cord-296469-h0ma163u 39 19 and and CC cord-296469-h0ma163u 39 20 vaccination vaccination NN cord-296469-h0ma163u 39 21 preparedness preparedness NN cord-296469-h0ma163u 39 22 : : : cord-296469-h0ma163u 39 23 -evidence -evidence NN cord-296469-h0ma163u 39 24 - - HYPH cord-296469-h0ma163u 39 25 based base VBN cord-296469-h0ma163u 39 26 increase increase NN cord-296469-h0ma163u 39 27 in in IN cord-296469-h0ma163u 39 28 seasonal seasonal JJ cord-296469-h0ma163u 39 29 influenza influenza NN cord-296469-h0ma163u 39 30 vaccine vaccine NN cord-296469-h0ma163u 39 31 use use NN cord-296469-h0ma163u 39 32 ; ; : cord-296469-h0ma163u 39 33 -increase -increase HYPH cord-296469-h0ma163u 39 34 in in RP cord-296469-h0ma163u 39 35 influenza influenza JJ cord-296469-h0ma163u 39 36 vaccine vaccine NN cord-296469-h0ma163u 39 37 production production NN cord-296469-h0ma163u 39 38 capacity capacity NN cord-296469-h0ma163u 39 39 and and CC cord-296469-h0ma163u 39 40 regulatory regulatory JJ cord-296469-h0ma163u 39 41 capacity capacity NN cord-296469-h0ma163u 39 42 ; ; : cord-296469-h0ma163u 39 43 -research -research : cord-296469-h0ma163u 39 44 and and CC cord-296469-h0ma163u 39 45 development development NN cord-296469-h0ma163u 39 46 for for IN cord-296469-h0ma163u 39 47 improved improve VBN cord-296469-h0ma163u 39 48 influenza influenza NN cord-296469-h0ma163u 39 49 vaccines vaccine NNS cord-296469-h0ma163u 39 50 . . . cord-296469-h0ma163u 40 1 The the DT cord-296469-h0ma163u 40 2 articles article NNS cord-296469-h0ma163u 40 3 contained contain VBN cord-296469-h0ma163u 40 4 in in IN cord-296469-h0ma163u 40 5 this this DT cord-296469-h0ma163u 40 6 issue issue NN cord-296469-h0ma163u 40 7 not not RB cord-296469-h0ma163u 40 8 only only RB cord-296469-h0ma163u 40 9 relate relate VBP cord-296469-h0ma163u 40 10 to to IN cord-296469-h0ma163u 40 11 the the DT cord-296469-h0ma163u 40 12 GAP gap NN cord-296469-h0ma163u 40 13 objectives objective NNS cord-296469-h0ma163u 40 14 but but CC cord-296469-h0ma163u 40 15 also also RB cord-296469-h0ma163u 40 16 reflect reflect VBP cord-296469-h0ma163u 40 17 the the DT cord-296469-h0ma163u 40 18 principles principle NNS cord-296469-h0ma163u 40 19 and and CC cord-296469-h0ma163u 40 20 goals goal NNS cord-296469-h0ma163u 40 21 of of IN cord-296469-h0ma163u 40 22 PIP PIP NNP cord-296469-h0ma163u 40 23 and and CC cord-296469-h0ma163u 40 24 highlight highlight VB cord-296469-h0ma163u 40 25 the the DT cord-296469-h0ma163u 40 26 synergy synergy NN cord-296469-h0ma163u 40 27 of of IN cord-296469-h0ma163u 40 28 these these DT cord-296469-h0ma163u 40 29 two two CD cord-296469-h0ma163u 40 30 efforts effort NNS cord-296469-h0ma163u 40 31 . . . cord-296469-h0ma163u 41 1 PIP PIP NNP cord-296469-h0ma163u 41 2 's 's POS cord-296469-h0ma163u 41 3 pandemic pandemic NN cord-296469-h0ma163u 41 4 preparedness preparedness NN cord-296469-h0ma163u 41 5 goal goal NN cord-296469-h0ma163u 41 6 of of IN cord-296469-h0ma163u 41 7 increasing increase VBG cord-296469-h0ma163u 41 8 the the DT cord-296469-h0ma163u 41 9 access access NN cord-296469-h0ma163u 41 10 to to IN cord-296469-h0ma163u 41 11 vaccines vaccine NNS cord-296469-h0ma163u 41 12 and and CC cord-296469-h0ma163u 41 13 other other JJ cord-296469-h0ma163u 41 14 pandemicrelated pandemicrelated JJ cord-296469-h0ma163u 41 15 supplies supply NNS cord-296469-h0ma163u 41 16 by by IN cord-296469-h0ma163u 41 17 developing develop VBG cord-296469-h0ma163u 41 18 countries country NNS cord-296469-h0ma163u 41 19 ( ( -LRB- cord-296469-h0ma163u 41 20 and and CC cord-296469-h0ma163u 41 21 the the DT cord-296469-h0ma163u 41 22 critical critical JJ cord-296469-h0ma163u 41 23 importance importance NN cord-296469-h0ma163u 41 24 of of IN cord-296469-h0ma163u 41 25 improving improve VBG cord-296469-h0ma163u 41 26 the the DT cord-296469-h0ma163u 41 27 sharing sharing NN cord-296469-h0ma163u 41 28 of of IN cord-296469-h0ma163u 41 29 influenza influenza NN cord-296469-h0ma163u 41 30 viruses virus NNS cord-296469-h0ma163u 41 31 with with IN cord-296469-h0ma163u 41 32 human human JJ cord-296469-h0ma163u 41 33 pandemic pandemic NN cord-296469-h0ma163u 41 34 potential potential NN cord-296469-h0ma163u 41 35 toward toward IN cord-296469-h0ma163u 41 36 that that DT cord-296469-h0ma163u 41 37 end end NN cord-296469-h0ma163u 41 38 ) ) -RRB- cord-296469-h0ma163u 41 39 , , , cord-296469-h0ma163u 41 40 will will MD cord-296469-h0ma163u 41 41 ultimately ultimately RB cord-296469-h0ma163u 41 42 depend depend VB cord-296469-h0ma163u 41 43 on on IN cord-296469-h0ma163u 41 44 influenza influenza JJ cord-296469-h0ma163u 41 45 vaccine vaccine NN cord-296469-h0ma163u 41 46 production production NN cord-296469-h0ma163u 41 47 capacity capacity NN cord-296469-h0ma163u 41 48 in in IN cord-296469-h0ma163u 41 49 place place NN cord-296469-h0ma163u 41 50 when when WRB cord-296469-h0ma163u 41 51 the the DT cord-296469-h0ma163u 41 52 next next JJ cord-296469-h0ma163u 41 53 pandemic pandemic NN cord-296469-h0ma163u 41 54 occurs occur VBZ cord-296469-h0ma163u 41 55 . . . cord-296469-h0ma163u 42 1 These these DT cord-296469-h0ma163u 42 2 articles article NNS cord-296469-h0ma163u 42 3 present present VBP cord-296469-h0ma163u 42 4 a a DT cord-296469-h0ma163u 42 5 variety variety NN cord-296469-h0ma163u 42 6 of of IN cord-296469-h0ma163u 42 7 perspectives perspective NNS cord-296469-h0ma163u 42 8 on on IN cord-296469-h0ma163u 42 9 the the DT cord-296469-h0ma163u 42 10 system system NN cord-296469-h0ma163u 42 11 that that WDT cord-296469-h0ma163u 42 12 will will MD cord-296469-h0ma163u 42 13 develop develop VB cord-296469-h0ma163u 42 14 , , , cord-296469-h0ma163u 42 15 produce produce VB cord-296469-h0ma163u 42 16 , , , cord-296469-h0ma163u 42 17 regulate regulate VB cord-296469-h0ma163u 42 18 , , , cord-296469-h0ma163u 42 19 distribute distribute VB cord-296469-h0ma163u 42 20 and and CC cord-296469-h0ma163u 42 21 evaluate evaluate VB cord-296469-h0ma163u 42 22 pandemic pandemic JJ cord-296469-h0ma163u 42 23 vaccines vaccine NNS cord-296469-h0ma163u 42 24 and and CC cord-296469-h0ma163u 42 25 mass mass JJ cord-296469-h0ma163u 42 26 vaccination vaccination NN cord-296469-h0ma163u 42 27 programmes programme NNS cord-296469-h0ma163u 42 28 . . . cord-296469-h0ma163u 43 1 They -PRON- PRP cord-296469-h0ma163u 43 2 have have VBP cord-296469-h0ma163u 43 3 been be VBN cord-296469-h0ma163u 43 4 selected select VBN cord-296469-h0ma163u 43 5 to to TO cord-296469-h0ma163u 43 6 represent represent VB cord-296469-h0ma163u 43 7 some some DT cord-296469-h0ma163u 43 8 of of IN cord-296469-h0ma163u 43 9 the the DT cord-296469-h0ma163u 43 10 many many JJ cord-296469-h0ma163u 43 11 elements element NNS cord-296469-h0ma163u 43 12 of of IN cord-296469-h0ma163u 43 13 the the DT cord-296469-h0ma163u 43 14 system system NN cord-296469-h0ma163u 43 15 that that WDT cord-296469-h0ma163u 43 16 will will MD cord-296469-h0ma163u 43 17 be be VB cord-296469-h0ma163u 43 18 necessary necessary JJ cord-296469-h0ma163u 43 19 for for IN cord-296469-h0ma163u 43 20 a a DT cord-296469-h0ma163u 43 21 pandemic pandemic NN cord-296469-h0ma163u 43 22 vaccine vaccine NN cord-296469-h0ma163u 43 23 response response NN cord-296469-h0ma163u 43 24 -including -include VBG cord-296469-h0ma163u 43 25 clinical clinical JJ cord-296469-h0ma163u 43 26 trials trial NNS cord-296469-h0ma163u 43 27 of of IN cord-296469-h0ma163u 43 28 new new JJ cord-296469-h0ma163u 43 29 vaccines vaccine NNS cord-296469-h0ma163u 43 30 , , , cord-296469-h0ma163u 43 31 new new JJ cord-296469-h0ma163u 43 32 vaccine vaccine NN cord-296469-h0ma163u 43 33 production production NN cord-296469-h0ma163u 43 34 platforms platform NNS cord-296469-h0ma163u 43 35 , , , cord-296469-h0ma163u 43 36 national national JJ cord-296469-h0ma163u 43 37 regulatory regulatory JJ cord-296469-h0ma163u 43 38 systems system NNS cord-296469-h0ma163u 43 39 , , , cord-296469-h0ma163u 43 40 implementation implementation NN cord-296469-h0ma163u 43 41 of of IN cord-296469-h0ma163u 43 42 policy policy NN cord-296469-h0ma163u 43 43 recommendations recommendation NNS cord-296469-h0ma163u 43 44 for for IN cord-296469-h0ma163u 43 45 vaccine vaccine NN cord-296469-h0ma163u 43 46 use use NN cord-296469-h0ma163u 43 47 , , , cord-296469-h0ma163u 43 48 and and CC cord-296469-h0ma163u 43 49 assessment assessment NN cord-296469-h0ma163u 43 50 of of IN cord-296469-h0ma163u 43 51 the the DT cord-296469-h0ma163u 43 52 sustainability sustainability NN cord-296469-h0ma163u 43 53 of of IN cord-296469-h0ma163u 43 54 the the DT cord-296469-h0ma163u 43 55 global global JJ cord-296469-h0ma163u 43 56 influenza influenza NN cord-296469-h0ma163u 43 57 vaccine vaccine NN cord-296469-h0ma163u 43 58 manufacturing manufacturing NN cord-296469-h0ma163u 43 59 capacity capacity NN cord-296469-h0ma163u 43 60 that that WDT cord-296469-h0ma163u 43 61 GAP GAP NNP cord-296469-h0ma163u 43 62 has have VBZ cord-296469-h0ma163u 43 63 supported support VBN cord-296469-h0ma163u 43 64 . . . cord-296469-h0ma163u 44 1 Progress progress NN cord-296469-h0ma163u 44 2 has have VBZ cord-296469-h0ma163u 44 3 already already RB cord-296469-h0ma163u 44 4 been be VBN cord-296469-h0ma163u 44 5 significant significant JJ cord-296469-h0ma163u 44 6 and and CC cord-296469-h0ma163u 44 7 measurable measurable JJ cord-296469-h0ma163u 44 8 . . . cord-296469-h0ma163u 45 1 One one CD cord-296469-h0ma163u 45 2 clear clear JJ cord-296469-h0ma163u 45 3 example example NN cord-296469-h0ma163u 45 4 is be VBZ cord-296469-h0ma163u 45 5 that that IN cord-296469-h0ma163u 45 6 global global JJ cord-296469-h0ma163u 45 7 production production NN cord-296469-h0ma163u 45 8 of of IN cord-296469-h0ma163u 45 9 seasonal seasonal JJ cord-296469-h0ma163u 45 10 influenza influenza NN cord-296469-h0ma163u 45 11 vaccine vaccine NN cord-296469-h0ma163u 45 12 increased increase VBD cord-296469-h0ma163u 45 13 from from IN cord-296469-h0ma163u 45 14 less less JJR cord-296469-h0ma163u 45 15 than than IN cord-296469-h0ma163u 45 16 500 500 CD cord-296469-h0ma163u 45 17 million million CD cord-296469-h0ma163u 45 18 doses dose NNS cord-296469-h0ma163u 45 19 in in IN cord-296469-h0ma163u 45 20 2006 2006 CD cord-296469-h0ma163u 45 21 to to IN cord-296469-h0ma163u 45 22 nearly nearly RB cord-296469-h0ma163u 45 23 1.5 1.5 CD cord-296469-h0ma163u 45 24 billion billion CD cord-296469-h0ma163u 45 25 doses dose NNS cord-296469-h0ma163u 45 26 in in IN cord-296469-h0ma163u 45 27 2015 2015 CD cord-296469-h0ma163u 45 28 [ [ -LRB- cord-296469-h0ma163u 45 29 16 16 CD cord-296469-h0ma163u 45 30 , , , cord-296469-h0ma163u 45 31 17 17 CD cord-296469-h0ma163u 45 32 ] ] -RRB- cord-296469-h0ma163u 45 33 . . . cord-296469-h0ma163u 46 1 Yet yet RB cord-296469-h0ma163u 46 2 , , , cord-296469-h0ma163u 46 3 there there EX cord-296469-h0ma163u 46 4 is be VBZ cord-296469-h0ma163u 46 5 a a DT cord-296469-h0ma163u 46 6 pressing press VBG cord-296469-h0ma163u 46 7 need need NN cord-296469-h0ma163u 46 8 for for IN cord-296469-h0ma163u 46 9 additional additional JJ cord-296469-h0ma163u 46 10 burden burden NN cord-296469-h0ma163u 46 11 of of IN cord-296469-h0ma163u 46 12 influenza influenza NN cord-296469-h0ma163u 46 13 illness illness NN cord-296469-h0ma163u 46 14 studies study NNS cord-296469-h0ma163u 46 15 to to TO cord-296469-h0ma163u 46 16 provide provide VB cord-296469-h0ma163u 46 17 the the DT cord-296469-h0ma163u 46 18 essential essential JJ cord-296469-h0ma163u 46 19 data datum NNS cord-296469-h0ma163u 46 20 that that WDT cord-296469-h0ma163u 46 21 will will MD cord-296469-h0ma163u 46 22 be be VB cord-296469-h0ma163u 46 23 looked look VBN cord-296469-h0ma163u 46 24 to to IN cord-296469-h0ma163u 46 25 by by IN cord-296469-h0ma163u 46 26 policymakers policymaker NNS cord-296469-h0ma163u 46 27 to to TO cord-296469-h0ma163u 46 28 assess assess VB cord-296469-h0ma163u 46 29 the the DT cord-296469-h0ma163u 46 30 role role NN cord-296469-h0ma163u 46 31 of of IN cord-296469-h0ma163u 46 32 vaccines vaccine NNS cord-296469-h0ma163u 46 33 in in IN cord-296469-h0ma163u 46 34 national national JJ cord-296469-h0ma163u 46 35 influenza influenza NN cord-296469-h0ma163u 46 36 control control NN cord-296469-h0ma163u 46 37 strategies strategy NNS cord-296469-h0ma163u 46 38 . . . cord-296469-h0ma163u 47 1 It -PRON- PRP cord-296469-h0ma163u 47 2 is be VBZ cord-296469-h0ma163u 47 3 the the DT cord-296469-h0ma163u 47 4 implementation implementation NN cord-296469-h0ma163u 47 5 of of IN cord-296469-h0ma163u 47 6 these these DT cord-296469-h0ma163u 47 7 policies policy NNS cord-296469-h0ma163u 47 8 that that WDT cord-296469-h0ma163u 47 9 will will MD cord-296469-h0ma163u 47 10 determine determine VB cord-296469-h0ma163u 47 11 demand demand NN cord-296469-h0ma163u 47 12 . . . cord-296469-h0ma163u 48 1 Without without IN cord-296469-h0ma163u 48 2 a a DT cord-296469-h0ma163u 48 3 concomitant concomitant JJ cord-296469-h0ma163u 48 4 increase increase NN cord-296469-h0ma163u 48 5 in in IN cord-296469-h0ma163u 48 6 global global JJ cord-296469-h0ma163u 48 7 demand demand NN cord-296469-h0ma163u 48 8 for for IN cord-296469-h0ma163u 48 9 seasonal seasonal JJ cord-296469-h0ma163u 48 10 influenza influenza NN cord-296469-h0ma163u 48 11 vaccine vaccine NN cord-296469-h0ma163u 48 12 , , , cord-296469-h0ma163u 48 13 the the DT cord-296469-h0ma163u 48 14 capacity capacity NN cord-296469-h0ma163u 48 15 that that WDT cord-296469-h0ma163u 48 16 will will MD cord-296469-h0ma163u 48 17 produce produce VB cord-296469-h0ma163u 48 18 the the DT cord-296469-h0ma163u 48 19 world world NN cord-296469-h0ma163u 48 20 's 's POS cord-296469-h0ma163u 48 21 pandemic pandemic NN cord-296469-h0ma163u 48 22 vaccines vaccine NNS cord-296469-h0ma163u 48 23 that that WDT cord-296469-h0ma163u 48 24 GAP GAP NNP cord-296469-h0ma163u 48 25 has have VBZ cord-296469-h0ma163u 48 26 stimulated stimulate VBN cord-296469-h0ma163u 48 27 can can MD cord-296469-h0ma163u 48 28 not not RB cord-296469-h0ma163u 48 29 be be VB cord-296469-h0ma163u 48 30 sustained sustain VBN cord-296469-h0ma163u 48 31 [ [ -LRB- cord-296469-h0ma163u 48 32 18 18 CD cord-296469-h0ma163u 48 33 ] ] -RRB- cord-296469-h0ma163u 48 34 . . . cord-296469-h0ma163u 49 1 At at IN cord-296469-h0ma163u 49 2 the the DT cord-296469-h0ma163u 49 3 end end NN cord-296469-h0ma163u 49 4 of of IN cord-296469-h0ma163u 49 5 the the DT cord-296469-h0ma163u 49 6 day day NN cord-296469-h0ma163u 49 7 there there EX cord-296469-h0ma163u 49 8 is be VBZ cord-296469-h0ma163u 49 9 the the DT cord-296469-h0ma163u 49 10 expectation expectation NN cord-296469-h0ma163u 49 11 that that IN cord-296469-h0ma163u 49 12 the the DT cord-296469-h0ma163u 49 13 efforts effort NNS cord-296469-h0ma163u 49 14 and and CC cord-296469-h0ma163u 49 15 investments investment NNS cord-296469-h0ma163u 49 16 made make VBN cord-296469-h0ma163u 49 17 to to TO cord-296469-h0ma163u 49 18 prepare prepare VB cord-296469-h0ma163u 49 19 for for IN cord-296469-h0ma163u 49 20 a a DT cord-296469-h0ma163u 49 21 pandemic pandemic NN cord-296469-h0ma163u 49 22 will will MD cord-296469-h0ma163u 49 23 result result VB cord-296469-h0ma163u 49 24 in in IN cord-296469-h0ma163u 49 25 the the DT cord-296469-h0ma163u 49 26 timely timely JJ cord-296469-h0ma163u 49 27 and and CC cord-296469-h0ma163u 49 28 equitable equitable JJ cord-296469-h0ma163u 49 29 availability availability NN cord-296469-h0ma163u 49 30 of of IN cord-296469-h0ma163u 49 31 a a DT cord-296469-h0ma163u 49 32 vaccine vaccine NN cord-296469-h0ma163u 49 33 that that WDT cord-296469-h0ma163u 49 34 is be VBZ cord-296469-h0ma163u 49 35 safe safe JJ cord-296469-h0ma163u 49 36 and and CC cord-296469-h0ma163u 49 37 effective effective JJ cord-296469-h0ma163u 49 38 , , , cord-296469-h0ma163u 49 39 and and CC cord-296469-h0ma163u 49 40 that that DT cord-296469-h0ma163u 49 41 can can MD cord-296469-h0ma163u 49 42 be be VB cord-296469-h0ma163u 49 43 used use VBN cord-296469-h0ma163u 49 44 in in IN cord-296469-h0ma163u 49 45 vaccination vaccination NN cord-296469-h0ma163u 49 46 campaigns campaign NNS cord-296469-h0ma163u 49 47 before before IN cord-296469-h0ma163u 49 48 the the DT cord-296469-h0ma163u 49 49 majority majority NN cord-296469-h0ma163u 49 50 of of IN cord-296469-h0ma163u 49 51 the the DT cord-296469-h0ma163u 49 52 global global JJ cord-296469-h0ma163u 49 53 population population NN cord-296469-h0ma163u 49 54 is be VBZ cord-296469-h0ma163u 49 55 exposed expose VBN cord-296469-h0ma163u 49 56 to to IN cord-296469-h0ma163u 49 57 the the DT cord-296469-h0ma163u 49 58 virus virus NN cord-296469-h0ma163u 49 59 . . . cord-296469-h0ma163u 50 1 However however RB cord-296469-h0ma163u 50 2 , , , cord-296469-h0ma163u 50 3 a a DT cord-296469-h0ma163u 50 4 continuing continue VBG cord-296469-h0ma163u 50 5 dedicated dedicated JJ cord-296469-h0ma163u 50 6 effort effort NN cord-296469-h0ma163u 50 7 is be VBZ cord-296469-h0ma163u 50 8 needed need VBN cord-296469-h0ma163u 50 9 to to TO cord-296469-h0ma163u 50 10 ensure ensure VB cord-296469-h0ma163u 50 11 that that IN cord-296469-h0ma163u 50 12 all all PDT cord-296469-h0ma163u 50 13 the the DT cord-296469-h0ma163u 50 14 elements element NNS cord-296469-h0ma163u 50 15 of of IN cord-296469-h0ma163u 50 16 the the DT cord-296469-h0ma163u 50 17 system system NN cord-296469-h0ma163u 50 18 that that WDT cord-296469-h0ma163u 50 19 will will MD cord-296469-h0ma163u 50 20 allow allow VB cord-296469-h0ma163u 50 21 this this DT cord-296469-h0ma163u 50 22 to to TO cord-296469-h0ma163u 50 23 happen happen VB cord-296469-h0ma163u 50 24 are be VBP cord-296469-h0ma163u 50 25 in in IN cord-296469-h0ma163u 50 26 place place NN cord-296469-h0ma163u 50 27 before before IN cord-296469-h0ma163u 50 28 we -PRON- PRP cord-296469-h0ma163u 50 29 need need VBP cord-296469-h0ma163u 50 30 them -PRON- PRP cord-296469-h0ma163u 50 31 . . . cord-296469-h0ma163u 51 1 Because because IN cord-296469-h0ma163u 51 2 we -PRON- PRP cord-296469-h0ma163u 51 3 do do VBP cord-296469-h0ma163u 51 4 n't not RB cord-296469-h0ma163u 51 5 know know VB cord-296469-h0ma163u 51 6 when when WRB cord-296469-h0ma163u 51 7 that that DT cord-296469-h0ma163u 51 8 day day NN cord-296469-h0ma163u 51 9 is be VBZ cord-296469-h0ma163u 51 10 , , , cord-296469-h0ma163u 51 11 the the DT cord-296469-h0ma163u 51 12 global global JJ cord-296469-h0ma163u 51 13 community community NN cord-296469-h0ma163u 51 14 must must MD cord-296469-h0ma163u 51 15 continue continue VB cord-296469-h0ma163u 51 16 with with IN cord-296469-h0ma163u 51 17 speed speed NN cord-296469-h0ma163u 51 18 and and CC cord-296469-h0ma163u 51 19 focus focus NN cord-296469-h0ma163u 51 20 . . . cord-296469-h0ma163u 52 1 And and CC cord-296469-h0ma163u 52 2 , , , cord-296469-h0ma163u 52 3 as as IN cord-296469-h0ma163u 52 4 WHO who WP cord-296469-h0ma163u 52 5 develops develop VBZ cord-296469-h0ma163u 52 6 a a DT cord-296469-h0ma163u 52 7 new new JJ cord-296469-h0ma163u 52 8 structure structure NN cord-296469-h0ma163u 52 9 to to TO cord-296469-h0ma163u 52 10 respond respond VB cord-296469-h0ma163u 52 11 for for IN cord-296469-h0ma163u 52 12 the the DT cord-296469-h0ma163u 52 13 call call NN cord-296469-h0ma163u 52 14 to to TO cord-296469-h0ma163u 52 15 be be VB cord-296469-h0ma163u 52 16 prepared prepare VBN cord-296469-h0ma163u 52 17 for for IN cord-296469-h0ma163u 52 18 all all DT cord-296469-h0ma163u 52 19 hazards hazard NNS cord-296469-h0ma163u 52 20 , , , cord-296469-h0ma163u 52 21 in in IN cord-296469-h0ma163u 52 22 its -PRON- PRP$ cord-296469-h0ma163u 52 23 complex complex JJ cord-296469-h0ma163u 52 24 organizational organizational JJ cord-296469-h0ma163u 52 25 chart chart NN cord-296469-h0ma163u 52 26 pandemic pandemic NN cord-296469-h0ma163u 52 27 influenza influenza NN cord-296469-h0ma163u 52 28 preparedness preparedness NN cord-296469-h0ma163u 52 29 must must MD cord-296469-h0ma163u 52 30 remain remain VB cord-296469-h0ma163u 52 31 front front JJ cord-296469-h0ma163u 52 32 and and CC cord-296469-h0ma163u 52 33 center center NN cord-296469-h0ma163u 52 34 . . . cord-296469-h0ma163u 53 1 The the DT cord-296469-h0ma163u 53 2 inclusive inclusive JJ cord-296469-h0ma163u 53 3 cost cost NN cord-296469-h0ma163u 53 4 of of IN cord-296469-h0ma163u 53 5 pandemic pandemic NN cord-296469-h0ma163u 53 6 influenza influenza NN cord-296469-h0ma163u 53 7 risk risk NN cord-296469-h0ma163u 53 8 ( ( -LRB- cord-296469-h0ma163u 53 9 working work VBG cord-296469-h0ma163u 53 10 paper paper NN cord-296469-h0ma163u 53 11 22137 22137 CD cord-296469-h0ma163u 53 12 ) ) -RRB- cord-296469-h0ma163u 54 1 An an DT cord-296469-h0ma163u 54 2 R&D r&d NN cord-296469-h0ma163u 54 3 blueprint blueprint NN cord-296469-h0ma163u 54 4 for for IN cord-296469-h0ma163u 54 5 action action NN cord-296469-h0ma163u 54 6 to to TO cord-296469-h0ma163u 54 7 prevent prevent VB cord-296469-h0ma163u 54 8 epidemics epidemic NNS cord-296469-h0ma163u 54 9 . . . cord-296469-h0ma163u 55 1 Accelerating accelerate VBG cord-296469-h0ma163u 55 2 R&D r&d NN cord-296469-h0ma163u 55 3 and and CC cord-296469-h0ma163u 55 4 saving save VBG cord-296469-h0ma163u 55 5 lives life NNS cord-296469-h0ma163u 55 6 . . . cord-296469-h0ma163u 56 1 Geneva Geneva NNP cord-296469-h0ma163u 56 2 : : : cord-296469-h0ma163u 57 1 World World NNP cord-296469-h0ma163u 57 2 Health Health NNP cord-296469-h0ma163u 57 3 Organization Organization NNP cord-296469-h0ma163u 57 4 Report Report NNP cord-296469-h0ma163u 57 5 from from IN cord-296469-h0ma163u 57 6 the the DT cord-296469-h0ma163u 57 7 World World NNP cord-296469-h0ma163u 57 8 Health Health NNP cord-296469-h0ma163u 57 9 Organization Organization NNP cord-296469-h0ma163u 57 10 's 's POS cord-296469-h0ma163u 57 11 Product Product NNP cord-296469-h0ma163u 57 12 Development Development NNP cord-296469-h0ma163u 57 13 for for IN cord-296469-h0ma163u 57 14 Vaccines Vaccines NNP cord-296469-h0ma163u 57 15 Advisory Advisory NNP cord-296469-h0ma163u 57 16 Committee Committee NNP cord-296469-h0ma163u 57 17 ( ( -LRB- cord-296469-h0ma163u 57 18 PDVAC PDVAC NNP cord-296469-h0ma163u 57 19 ) ) -RRB- cord-296469-h0ma163u 57 20 meeting meet VBG cord-296469-h0ma163u 57 21 Antibiotic antibiotic JJ cord-296469-h0ma163u 57 22 resistance resistance NN cord-296469-h0ma163u 57 23 threats threat NNS cord-296469-h0ma163u 57 24 in in IN cord-296469-h0ma163u 57 25 the the DT cord-296469-h0ma163u 57 26 United United NNP cord-296469-h0ma163u 57 27 States States NNP cord-296469-h0ma163u 58 1 The the DT cord-296469-h0ma163u 58 2 Coalition Coalition NNP cord-296469-h0ma163u 58 3 for for IN cord-296469-h0ma163u 58 4 Epidemic Epidemic NNP cord-296469-h0ma163u 58 5 Preparedness Preparedness NNP cord-296469-h0ma163u 58 6 Innovations Innovations NNPS cord-296469-h0ma163u 58 7 ( ( -LRB- cord-296469-h0ma163u 58 8 CEPI CEPI NNP cord-296469-h0ma163u 58 9 ) ) -RRB- cord-296469-h0ma163u 59 1 Establishing establish VBG cord-296469-h0ma163u 59 2 a a DT cord-296469-h0ma163u 59 3 global global JJ cord-296469-h0ma163u 59 4 vaccine vaccine NN cord-296469-h0ma163u 59 5 - - HYPH cord-296469-h0ma163u 59 6 development development NN cord-296469-h0ma163u 59 7 fund fund NN cord-296469-h0ma163u 59 8 ( ( -LRB- cord-296469-h0ma163u 59 9 perspective perspective NN cord-296469-h0ma163u 59 10 ) ) -RRB- cord-296469-h0ma163u 60 1 The the DT cord-296469-h0ma163u 60 2 compelling compelling JJ cord-296469-h0ma163u 60 3 need need NN cord-296469-h0ma163u 60 4 for for IN cord-296469-h0ma163u 60 5 game game NN cord-296469-h0ma163u 60 6 - - HYPH cord-296469-h0ma163u 60 7 changing change VBG cord-296469-h0ma163u 60 8 influenza influenza NN cord-296469-h0ma163u 60 9 vaccines vaccine NNS cord-296469-h0ma163u 60 10 edu edu NN cord-296469-h0ma163u 60 11 / / SYM cord-296469-h0ma163u 60 12 compelling compelling JJ cord-296469-h0ma163u 60 13 - - HYPH cord-296469-h0ma163u 60 14 need need NN cord-296469-h0ma163u 60 15 - - HYPH cord-296469-h0ma163u 60 16 game game NN cord-296469-h0ma163u 60 17 - - HYPH cord-296469-h0ma163u 60 18 changing change VBG cord-296469-h0ma163u 60 19 - - HYPH cord-296469-h0ma163u 60 20 influenza influenza NN cord-296469-h0ma163u 60 21 - - HYPH cord-296469-h0ma163u 60 22 vaccines vaccine NNS cord-296469-h0ma163u 61 1 > > XX cord-296469-h0ma163u 61 2 Advances advance NNS cord-296469-h0ma163u 61 3 in in IN cord-296469-h0ma163u 61 4 the the DT cord-296469-h0ma163u 61 5 development development NN cord-296469-h0ma163u 61 6 of of IN cord-296469-h0ma163u 61 7 influenza influenza NN cord-296469-h0ma163u 61 8 virus virus NN cord-296469-h0ma163u 61 9 vaccines vaccine NNS cord-296469-h0ma163u 61 10 Induction Induction NNP cord-296469-h0ma163u 61 11 of of IN cord-296469-h0ma163u 61 12 unnatural unnatural JJ cord-296469-h0ma163u 61 13 immunity immunity NN cord-296469-h0ma163u 61 14 : : : cord-296469-h0ma163u 61 15 prospects prospect NNS cord-296469-h0ma163u 61 16 for for IN cord-296469-h0ma163u 61 17 a a DT cord-296469-h0ma163u 61 18 broadly broadly RB cord-296469-h0ma163u 61 19 protective protective JJ cord-296469-h0ma163u 61 20 universal universal JJ cord-296469-h0ma163u 61 21 influenza influenza NN cord-296469-h0ma163u 61 22 vaccine vaccine NN cord-296469-h0ma163u 61 23 ( ( -LRB- cord-296469-h0ma163u 61 24 commentary commentary NN cord-296469-h0ma163u 61 25 ) ) -RRB- cord-296469-h0ma163u 62 1 Global Global NNP cord-296469-h0ma163u 62 2 Vaccine Vaccine NNP cord-296469-h0ma163u 62 3 Action Action NNP cord-296469-h0ma163u 62 4 Plan Plan NNP cord-296469-h0ma163u 62 5 2011 2011 CD cord-296469-h0ma163u 62 6 - - SYM cord-296469-h0ma163u 62 7 2020 2020 CD cord-296469-h0ma163u 62 8 . . . cord-296469-h0ma163u 63 1 Geneva Geneva NNP cord-296469-h0ma163u 63 2 : : : cord-296469-h0ma163u 64 1 World World NNP cord-296469-h0ma163u 64 2 Health Health NNP cord-296469-h0ma163u 64 3 Organization Organization NNP cord-296469-h0ma163u 64 4 SAGE SAGE NNP cord-296469-h0ma163u 64 5 Working Working NNP cord-296469-h0ma163u 64 6 Group Group NNP cord-296469-h0ma163u 64 7 on on IN cord-296469-h0ma163u 64 8 Vaccine Vaccine NNP cord-296469-h0ma163u 64 9 Hesitancy Hesitancy NNP cord-296469-h0ma163u 64 10 . . . cord-296469-h0ma163u 65 1 How how WRB cord-296469-h0ma163u 65 2 to to TO cord-296469-h0ma163u 65 3 deal deal VB cord-296469-h0ma163u 65 4 with with IN cord-296469-h0ma163u 65 5 vaccine vaccine NN cord-296469-h0ma163u 65 6 hesitancy hesitancy NN cord-296469-h0ma163u 65 7 ? ? . cord-296469-h0ma163u 66 1 Global Global NNP cord-296469-h0ma163u 66 2 Action Action NNP cord-296469-h0ma163u 66 3 Plan Plan NNP cord-296469-h0ma163u 66 4 for for IN cord-296469-h0ma163u 66 5 Influenza Influenza NNP cord-296469-h0ma163u 66 6 Vaccines Vaccines NNPS cord-296469-h0ma163u 66 7 . . . cord-296469-h0ma163u 67 1 Geneva Geneva NNP cord-296469-h0ma163u 67 2 : : : cord-296469-h0ma163u 68 1 World World NNP cord-296469-h0ma163u 68 2 Health Health NNP cord-296469-h0ma163u 68 3 Organization Organization NNP cord-296469-h0ma163u 68 4 Pandemic Pandemic NNP cord-296469-h0ma163u 68 5 Influenza Influenza NNP cord-296469-h0ma163u 68 6 Preparedness Preparedness NNP cord-296469-h0ma163u 68 7 ( ( -LRB- cord-296469-h0ma163u 68 8 PIP PIP NNP cord-296469-h0ma163u 68 9 ) ) -RRB- cord-296469-h0ma163u 68 10 Framework Framework NNP cord-296469-h0ma163u 68 11 . . . cord-296469-h0ma163u 69 1 Geneva Geneva NNP cord-296469-h0ma163u 69 2 : : : cord-296469-h0ma163u 70 1 World World NNP cord-296469-h0ma163u 70 2 Health Health NNP cord-296469-h0ma163u 70 3 Organization Organization NNP cord-296469-h0ma163u 70 4 Melbourne Melbourne NNP cord-296469-h0ma163u 70 5 : : : cord-296469-h0ma163u 70 6 Peter Peter NNP cord-296469-h0ma163u 70 7 Doherty Doherty NNP cord-296469-h0ma163u 70 8 Institute Institute NNP cord-296469-h0ma163u 70 9 for for IN cord-296469-h0ma163u 70 10 Infection Infection NNP cord-296469-h0ma163u 70 11 and and CC cord-296469-h0ma163u 70 12 Immunity Immunity NNP cord-296469-h0ma163u 70 13 Global Global NNP cord-296469-h0ma163u 70 14 Action Action NNP cord-296469-h0ma163u 70 15 Plan Plan NNP cord-296469-h0ma163u 70 16 for for IN cord-296469-h0ma163u 71 1 Influenza Influenza NNP cord-296469-h0ma163u 71 2 Vaccines Vaccines NNPS cord-296469-h0ma163u 71 3 A a DT cord-296469-h0ma163u 71 4 literature literature NN cord-296469-h0ma163u 71 5 review review NN cord-296469-h0ma163u 71 6 to to TO cord-296469-h0ma163u 71 7 identify identify VB cord-296469-h0ma163u 71 8 factors factor NNS cord-296469-h0ma163u 71 9 that that WDT cord-296469-h0ma163u 71 10 determine determine VBP cord-296469-h0ma163u 71 11 policies policy NNS cord-296469-h0ma163u 71 12 for for IN cord-296469-h0ma163u 71 13 influenza influenza NN cord-296469-h0ma163u 71 14 vaccination vaccination NN