id	sid	tid	token	lemma	pos
cord-304485-vouu56rr	1	1	key	key	JJ
cord-304485-vouu56rr	1	2	:	:	:
cord-304485-vouu56rr	1	3	cord-304485-vouu56rr	cord-304485-vouu56rr	XX
cord-304485-vouu56rr	2	1	authors	author	NNS
cord-304485-vouu56rr	2	2	:	:	:
cord-304485-vouu56rr	2	3	Bengoechea	Bengoechea	NNP
cord-304485-vouu56rr	2	4	,	,	,
cord-304485-vouu56rr	2	5	Jose	Jose	NNP
cord-304485-vouu56rr	2	6	A	a	DT
cord-304485-vouu56rr	2	7	title	title	NN
cord-304485-vouu56rr	2	8	:	:	:
cord-304485-vouu56rr	2	9	Viruses	virus	NNS
cord-304485-vouu56rr	2	10	to	to	TO
cord-304485-vouu56rr	2	11	fight	fight	VB
cord-304485-vouu56rr	2	12	other	other	JJ
cord-304485-vouu56rr	2	13	viruses	virus	NNS
cord-304485-vouu56rr	2	14	:	:	:
cord-304485-vouu56rr	2	15	the	the	DT
cord-304485-vouu56rr	2	16	influenza	influenza	NN
cord-304485-vouu56rr	2	17	vaccine	vaccine	NN
cord-304485-vouu56rr	2	18	case	case	NN
cord-304485-vouu56rr	2	19	date	date	NN
cord-304485-vouu56rr	2	20	:	:	:
cord-304485-vouu56rr	2	21	2020	2020	CD
cord-304485-vouu56rr	2	22	-	-	HYPH
cord-304485-vouu56rr	2	23	04	04	CD
cord-304485-vouu56rr	2	24	-	-	SYM
cord-304485-vouu56rr	2	25	22	22	CD
cord-304485-vouu56rr	2	26	journal	journal	NN
cord-304485-vouu56rr	2	27	:	:	:
cord-304485-vouu56rr	2	28	EMBO	EMBO	NNP
cord-304485-vouu56rr	2	29	Mol	Mol	NNP
cord-304485-vouu56rr	2	30	Med	Med	NNP
cord-304485-vouu56rr	2	31	DOI	doi	NN
cord-304485-vouu56rr	2	32	:	:	:
cord-304485-vouu56rr	2	33	10.15252	10.15252	CD
cord-304485-vouu56rr	2	34	/	/	SYM
cord-304485-vouu56rr	2	35	emmm.202012059	emmm.202012059	NNP
cord-304485-vouu56rr	2	36	sha	sha	NNP
cord-304485-vouu56rr	2	37	:	:	:
cord-304485-vouu56rr	2	38	1f8d30466ceebe01d54f02c0f3fa49de023b1600	1f8d30466ceebe01d54f02c0f3fa49de023b1600	CD
cord-304485-vouu56rr	2	39	doc_id	doc_id	CD
cord-304485-vouu56rr	2	40	:	:	:
cord-304485-vouu56rr	2	41	304485	304485	CD
cord-304485-vouu56rr	2	42	cord_uid	cord_uid	NNS
cord-304485-vouu56rr	2	43	:	:	:
cord-304485-vouu56rr	2	44	vouu56rr	vouu56rr	NN
cord-304485-vouu56rr	3	1	Undoubtedly	undoubtedly	RB
cord-304485-vouu56rr	3	2	,	,	,
cord-304485-vouu56rr	3	3	vaccination	vaccination	NN
cord-304485-vouu56rr	3	4	is	be	VBZ
cord-304485-vouu56rr	3	5	one	one	CD
cord-304485-vouu56rr	3	6	of	of	IN
cord-304485-vouu56rr	3	7	the	the	DT
cord-304485-vouu56rr	3	8	health	health	NN
cord-304485-vouu56rr	3	9	interventions	intervention	NNS
cord-304485-vouu56rr	3	10	showing	show	VBG
cord-304485-vouu56rr	3	11	major	major	JJ
cord-304485-vouu56rr	3	12	impact	impact	NN
cord-304485-vouu56rr	3	13	on	on	IN
cord-304485-vouu56rr	3	14	humankind	humankind	NN
cord-304485-vouu56rr	3	15	.	.	.
cord-304485-vouu56rr	4	1	Vaccines	vaccine	NNS
cord-304485-vouu56rr	4	2	remain	remain	VBP
cord-304485-vouu56rr	4	3	one	one	CD
cord-304485-vouu56rr	4	4	of	of	IN
cord-304485-vouu56rr	4	5	the	the	DT
cord-304485-vouu56rr	4	6	most	most	RBS
cord-304485-vouu56rr	4	7	effective	effective	JJ
cord-304485-vouu56rr	4	8	and	and	CC
cord-304485-vouu56rr	4	9	safest	safe	JJS
cord-304485-vouu56rr	4	10	ways	way	NNS
cord-304485-vouu56rr	4	11	to	to	TO
cord-304485-vouu56rr	4	12	tackle	tackle	VB
cord-304485-vouu56rr	4	13	infections	infection	NNS
cord-304485-vouu56rr	4	14	.	.	.
cord-304485-vouu56rr	5	1	The	the	DT
cord-304485-vouu56rr	5	2	current	current	JJ
cord-304485-vouu56rr	5	3	coronavirus	coronavirus	NN
cord-304485-vouu56rr	5	4	pandemic	pandemic	NN
cord-304485-vouu56rr	5	5	is	be	VBZ
cord-304485-vouu56rr	5	6	not	not	RB
cord-304485-vouu56rr	5	7	an	an	DT
cord-304485-vouu56rr	5	8	exception	exception	NN
cord-304485-vouu56rr	5	9	,	,	,
cord-304485-vouu56rr	5	10	and	and	CC
cord-304485-vouu56rr	5	11	we	-PRON-	PRP
cord-304485-vouu56rr	5	12	all	all	DT
cord-304485-vouu56rr	5	13	hope	hope	VBP
cord-304485-vouu56rr	5	14	that	that	IN
cord-304485-vouu56rr	5	15	ongoing	ongoing	JJ
cord-304485-vouu56rr	5	16	international	international	JJ
cord-304485-vouu56rr	5	17	efforts	effort	NNS
cord-304485-vouu56rr	5	18	will	will	MD
cord-304485-vouu56rr	5	19	succeed	succeed	VB
cord-304485-vouu56rr	5	20	in	in	IN
cord-304485-vouu56rr	5	21	developing	develop	VBG
cord-304485-vouu56rr	5	22	a	a	DT
cord-304485-vouu56rr	5	23	vaccine	vaccine	NN
cord-304485-vouu56rr	5	24	soon	soon	RB
cord-304485-vouu56rr	5	25	.	.	.
cord-304485-vouu56rr	6	1	In	in	IN
cord-304485-vouu56rr	6	2	this	this	DT
cord-304485-vouu56rr	6	3	scenario	scenario	NN
cord-304485-vouu56rr	6	4	,	,	,
cord-304485-vouu56rr	6	5	the	the	DT
cord-304485-vouu56rr	6	6	present	present	JJ
cord-304485-vouu56rr	6	7	work	work	NN
cord-304485-vouu56rr	6	8	published	publish	VBN
cord-304485-vouu56rr	6	9	in	in	IN
cord-304485-vouu56rr	6	10	this	this	DT
cord-304485-vouu56rr	6	11	edition	edition	NN
cord-304485-vouu56rr	6	12	of	of	IN
cord-304485-vouu56rr	6	13	EMBO	EMBO	NNP
cord-304485-vouu56rr	6	14	Molecular	Molecular	NNP
cord-304485-vouu56rr	6	15	Medicine	Medicine	NNP
cord-304485-vouu56rr	6	16	by	by	IN
cord-304485-vouu56rr	6	17	Demminger	Demminger	NNP
cord-304485-vouu56rr	6	18	and	and	CC
cord-304485-vouu56rr	6	19	colleagues	colleague	NNS
cord-304485-vouu56rr	7	1	(	(	-LRB-
cord-304485-vouu56rr	7	2	Demminger	Demminger	NNP
cord-304485-vouu56rr	7	3	et	et	FW
cord-304485-vouu56rr	7	4	al	al	NNP
cord-304485-vouu56rr	7	5	,	,	,
cord-304485-vouu56rr	7	6	2020	2020	CD
cord-304485-vouu56rr	7	7	)	)	-RRB-
cord-304485-vouu56rr	7	8	is	be	VBZ
cord-304485-vouu56rr	7	9	timeliness	timeliness	NN
cord-304485-vouu56rr	7	10	to	to	TO
cord-304485-vouu56rr	7	11	exemplify	exemplify	VB
cord-304485-vouu56rr	7	12	the	the	DT
cord-304485-vouu56rr	7	13	steps	step	NNS
cord-304485-vouu56rr	7	14	needed	need	VBN
cord-304485-vouu56rr	7	15	to	to	TO
cord-304485-vouu56rr	7	16	develop	develop	VB
cord-304485-vouu56rr	7	17	effective	effective	JJ
cord-304485-vouu56rr	7	18	vaccines	vaccine	NNS
cord-304485-vouu56rr	7	19	.	.	.
cord-304485-vouu56rr	8	1	T	T	NNP
cord-304485-vouu56rr	9	1	his	-PRON-	PRP$
cord-304485-vouu56rr	9	2	study	study	NN
cord-304485-vouu56rr	9	3	focuses	focus	VBZ
cord-304485-vouu56rr	9	4	on	on	IN
cord-304485-vouu56rr	9	5	influenza	influenza	NN
cord-304485-vouu56rr	9	6	,	,	,
cord-304485-vouu56rr	9	7	a	a	DT
cord-304485-vouu56rr	9	8	seasonal	seasonal	JJ
cord-304485-vouu56rr	9	9	pandemic	pandemic	NN
cord-304485-vouu56rr	9	10	with	with	IN
cord-304485-vouu56rr	9	11	major	major	JJ
cord-304485-vouu56rr	9	12	annual	annual	JJ
cord-304485-vouu56rr	9	13	impact	impact	NN
cord-304485-vouu56rr	9	14	on	on	IN
cord-304485-vouu56rr	9	15	the	the	DT
cord-304485-vouu56rr	9	16	health	health	NN
cord-304485-vouu56rr	9	17	systems	system	NNS
cord-304485-vouu56rr	9	18	worldwide	worldwide	RB
cord-304485-vouu56rr	9	19	.	.	.
cord-304485-vouu56rr	10	1	This	this	DT
cord-304485-vouu56rr	10	2	infection	infection	NN
cord-304485-vouu56rr	10	3	is	be	VBZ
cord-304485-vouu56rr	10	4	associated	associate	VBN
cord-304485-vouu56rr	10	5	with	with	IN
cord-304485-vouu56rr	10	6	high	high	JJ
cord-304485-vouu56rr	10	7	mortality	mortality	NN
cord-304485-vouu56rr	10	8	and	and	CC
cord-304485-vouu56rr	10	9	morbidity	morbidity	NN
cord-304485-vouu56rr	10	10	in	in	IN
cord-304485-vouu56rr	10	11	very	very	RB
cord-304485-vouu56rr	10	12	young	young	JJ
cord-304485-vouu56rr	10	13	and	and	CC
cord-304485-vouu56rr	10	14	old	old	JJ
cord-304485-vouu56rr	10	15	individuals	individual	NNS
cord-304485-vouu56rr	10	16	.	.	.
cord-304485-vouu56rr	11	1	Stories	story	NNS
cord-304485-vouu56rr	11	2	in	in	IN
cord-304485-vouu56rr	11	3	the	the	DT
cord-304485-vouu56rr	11	4	recent	recent	JJ
cord-304485-vouu56rr	11	5	news	news	NN
cord-304485-vouu56rr	11	6	have	have	VBP
cord-304485-vouu56rr	11	7	highlighted	highlight	VBN
cord-304485-vouu56rr	11	8	the	the	DT
cord-304485-vouu56rr	11	9	unusual	unusual	JJ
cord-304485-vouu56rr	11	10	deadly	deadly	JJ
cord-304485-vouu56rr	11	11	influenza	influenza	NN
cord-304485-vouu56rr	11	12	pandemic	pandemic	NN
cord-304485-vouu56rr	11	13	lasting	last	VBG
cord-304485-vouu56rr	11	14	from	from	IN
cord-304485-vouu56rr	11	15	1918	1918	CD
cord-304485-vouu56rr	11	16	to	to	IN
cord-304485-vouu56rr	11	17	1920	1920	CD
cord-304485-vouu56rr	11	18	,	,	,
cord-304485-vouu56rr	11	19	the	the	DT
cord-304485-vouu56rr	11	20	so	so	RB
cord-304485-vouu56rr	11	21	-	-	HYPH
cord-304485-vouu56rr	11	22	called	call	VBN
cord-304485-vouu56rr	11	23	Spanish	spanish	JJ
cord-304485-vouu56rr	11	24	flu	flu	NN
cord-304485-vouu56rr	11	25	,	,	,
cord-304485-vouu56rr	11	26	highlighting	highlight	VBG
cord-304485-vouu56rr	11	27	the	the	DT
cord-304485-vouu56rr	11	28	devastating	devastating	JJ
cord-304485-vouu56rr	11	29	impact	impact	NN
cord-304485-vouu56rr	11	30	of	of	IN
cord-304485-vouu56rr	11	31	these	these	DT
cord-304485-vouu56rr	11	32	viral	viral	JJ
cord-304485-vouu56rr	11	33	infections	infection	NNS
cord-304485-vouu56rr	11	34	.	.	.
cord-304485-vouu56rr	12	1	The	the	DT
cord-304485-vouu56rr	12	2	current	current	JJ
cord-304485-vouu56rr	12	3	influenza	influenza	NN
cord-304485-vouu56rr	12	4	prophylaxis	prophylaxis	NN
cord-304485-vouu56rr	12	5	is	be	VBZ
cord-304485-vouu56rr	12	6	based	base	VBN
cord-304485-vouu56rr	12	7	on	on	IN
cord-304485-vouu56rr	12	8	immunization	immunization	NN
cord-304485-vouu56rr	12	9	with	with	IN
cord-304485-vouu56rr	12	10	trivalent	trivalent	JJ
cord-304485-vouu56rr	12	11	or	or	CC
cord-304485-vouu56rr	12	12	quadrivalent	quadrivalent	JJ
cord-304485-vouu56rr	12	13	influenza	influenza	NN
cord-304485-vouu56rr	12	14	vaccines	vaccine	NNS
cord-304485-vouu56rr	12	15	containing	contain	VBG
cord-304485-vouu56rr	12	16	antigens	antigen	NNS
cord-304485-vouu56rr	12	17	from	from	IN
cord-304485-vouu56rr	12	18	influenza	influenza	NN
cord-304485-vouu56rr	12	19	A	a	NN
cord-304485-vouu56rr	12	20	and	and	CC
cord-304485-vouu56rr	12	21	B	b	NN
cord-304485-vouu56rr	12	22	viruses	virus	NNS
cord-304485-vouu56rr	12	23	.	.	.
cord-304485-vouu56rr	13	1	However	however	RB
cord-304485-vouu56rr	13	2	,	,	,
cord-304485-vouu56rr	13	3	this	this	DT
cord-304485-vouu56rr	13	4	vaccine	vaccine	NN
cord-304485-vouu56rr	13	5	is	be	VBZ
cord-304485-vouu56rr	13	6	mostly	mostly	RB
cord-304485-vouu56rr	13	7	strain	strain	NN
cord-304485-vouu56rr	13	8	specific	specific	JJ
cord-304485-vouu56rr	13	9	and	and	CC
cord-304485-vouu56rr	13	10	the	the	DT
cord-304485-vouu56rr	13	11	process	process	NN
cord-304485-vouu56rr	13	12	to	to	TO
cord-304485-vouu56rr	13	13	produce	produce	VB
cord-304485-vouu56rr	13	14	it	-PRON-	PRP
cord-304485-vouu56rr	13	15	is	be	VBZ
cord-304485-vouu56rr	13	16	timeconsuming	timeconsuming	JJ
cord-304485-vouu56rr	13	17	.	.	.
cord-304485-vouu56rr	14	1	In	in	IN
cord-304485-vouu56rr	14	2	addition	addition	NN
cord-304485-vouu56rr	14	3	,	,	,
cord-304485-vouu56rr	14	4	evidence	evidence	NN
cord-304485-vouu56rr	14	5	indicates	indicate	VBZ
cord-304485-vouu56rr	14	6	it	-PRON-	PRP
cord-304485-vouu56rr	14	7	does	do	VBZ
cord-304485-vouu56rr	14	8	not	not	RB
cord-304485-vouu56rr	14	9	provide	provide	VB
cord-304485-vouu56rr	14	10	protection	protection	NN
cord-304485-vouu56rr	14	11	against	against	IN
cord-304485-vouu56rr	14	12	emerging	emerge	VBG
cord-304485-vouu56rr	14	13	zoonotic	zoonotic	JJ
cord-304485-vouu56rr	14	14	influenza	influenza	NN
cord-304485-vouu56rr	14	15	A	a	DT
cord-304485-vouu56rr	14	16	virus	virus	NN
cord-304485-vouu56rr	14	17	strains	strain	NNS
cord-304485-vouu56rr	14	18	.	.	.
cord-304485-vouu56rr	15	1	Overall	overall	RB
cord-304485-vouu56rr	15	2	,	,	,
cord-304485-vouu56rr	15	3	the	the	DT
cord-304485-vouu56rr	15	4	need	need	NN
cord-304485-vouu56rr	15	5	to	to	TO
cord-304485-vouu56rr	15	6	develop	develop	VB
cord-304485-vouu56rr	15	7	a	a	DT
cord-304485-vouu56rr	15	8	novel	novel	JJ
cord-304485-vouu56rr	15	9	vaccine	vaccine	NN
cord-304485-vouu56rr	15	10	conferring	confer	VBG
cord-304485-vouu56rr	15	11	protection	protection	NN
cord-304485-vouu56rr	15	12	as	as	RB
cord-304485-vouu56rr	15	13	broad	broad	JJ
cord-304485-vouu56rr	15	14	as	as	IN
cord-304485-vouu56rr	15	15	possible	possible	JJ
cord-304485-vouu56rr	15	16	is	be	VBZ
cord-304485-vouu56rr	15	17	widely	widely	RB
cord-304485-vouu56rr	15	18	acknowledged	acknowledge	VBN
cord-304485-vouu56rr	15	19	.	.	.
cord-304485-vouu56rr	16	1	One	one	CD
cord-304485-vouu56rr	16	2	observation	observation	NN
cord-304485-vouu56rr	16	3	key	key	NN
cord-304485-vouu56rr	16	4	for	for	IN
cord-304485-vouu56rr	16	5	this	this	DT
cord-304485-vouu56rr	16	6	work	work	NN
cord-304485-vouu56rr	16	7	is	be	VBZ
cord-304485-vouu56rr	16	8	the	the	DT
cord-304485-vouu56rr	16	9	discovery	discovery	NN
cord-304485-vouu56rr	16	10	of	of	IN
cord-304485-vouu56rr	16	11	protective	protective	JJ
cord-304485-vouu56rr	16	12	antibodies	antibody	NNS
cord-304485-vouu56rr	16	13	against	against	IN
cord-304485-vouu56rr	16	14	the	the	DT
cord-304485-vouu56rr	16	15	surface	surface	NN
cord-304485-vouu56rr	16	16	glycoprotein	glycoprotein	NN
cord-304485-vouu56rr	16	17	hemagglutinin	hemagglutinin	NN
cord-304485-vouu56rr	16	18	(	(	-LRB-
cord-304485-vouu56rr	16	19	HA	HA	NNP
cord-304485-vouu56rr	16	20	)	)	-RRB-
cord-304485-vouu56rr	16	21	acting	act	VBG
cord-304485-vouu56rr	16	22	via	via	IN
cord-304485-vouu56rr	16	23	interference	interference	NN
cord-304485-vouu56rr	16	24	with	with	IN
cord-304485-vouu56rr	16	25	viral	viral	JJ
cord-304485-vouu56rr	16	26	replication	replication	NN
cord-304485-vouu56rr	16	27	or	or	CC
cord-304485-vouu56rr	16	28	via	via	IN
cord-304485-vouu56rr	16	29	Fc	Fc	NNP
cord-304485-vouu56rr	16	30	-	-	HYPH
cord-304485-vouu56rr	16	31	receptor	receptor	NN
cord-304485-vouu56rr	16	32	-	-	HYPH
cord-304485-vouu56rr	16	33	mediated	mediate	VBN
cord-304485-vouu56rr	16	34	cellular	cellular	JJ
cord-304485-vouu56rr	16	35	cytoxicity	cytoxicity	NN
cord-304485-vouu56rr	16	36	(	(	-LRB-
cord-304485-vouu56rr	16	37	DiLillo	DiLillo	NNP
cord-304485-vouu56rr	16	38	et	et	NNP
cord-304485-vouu56rr	16	39	al	al	NNP
cord-304485-vouu56rr	16	40	,	,	,
cord-304485-vouu56rr	16	41	2016	2016	CD
cord-304485-vouu56rr	16	42	;	;	.
cord-304485-vouu56rr	17	1	Wu	Wu	NNP
cord-304485-vouu56rr	17	2	&	&	CC
cord-304485-vouu56rr	17	3	Wilson	Wilson	NNP
cord-304485-vouu56rr	17	4	,	,	,
cord-304485-vouu56rr	17	5	2017	2017	CD
cord-304485-vouu56rr	17	6	)	)	-RRB-
cord-304485-vouu56rr	17	7	.	.	.
cord-304485-vouu56rr	18	1	Demminger	Demminger	NNP
cord-304485-vouu56rr	18	2	and	and	CC
cord-304485-vouu56rr	18	3	colleagues	colleague	NNS
cord-304485-vouu56rr	18	4	decided	decide	VBD
cord-304485-vouu56rr	18	5	to	to	TO
cord-304485-vouu56rr	18	6	exploit	exploit	VB
cord-304485-vouu56rr	18	7	an	an	DT
cord-304485-vouu56rr	18	8	adeno	adeno	NN
cord-304485-vouu56rr	18	9	-	-	HYPH
cord-304485-vouu56rr	18	10	associated	associate	VBN
cord-304485-vouu56rr	18	11	virus	virus	NN
cord-304485-vouu56rr	18	12	(	(	-LRB-
cord-304485-vouu56rr	18	13	AAV	AAV	NNP
cord-304485-vouu56rr	18	14	)	)	-RRB-
cord-304485-vouu56rr	18	15	vector	vector	NN
cord-304485-vouu56rr	18	16	to	to	TO
cord-304485-vouu56rr	18	17	express	express	VB
cord-304485-vouu56rr	18	18	influenza	influenza	NN
cord-304485-vouu56rr	18	19	antigens	antigen	NNS
cord-304485-vouu56rr	18	20	to	to	TO
cord-304485-vouu56rr	18	21	elicit	elicit	VB
cord-304485-vouu56rr	18	22	protective	protective	JJ
cord-304485-vouu56rr	18	23	antibody	antibody	NN
cord-304485-vouu56rr	18	24	responses	response	NNS
cord-304485-vouu56rr	18	25	.	.	.
cord-304485-vouu56rr	19	1	The	the	DT
cord-304485-vouu56rr	19	2	selection	selection	NN
cord-304485-vouu56rr	19	3	of	of	IN
cord-304485-vouu56rr	19	4	AAV	AAV	NNP
cord-304485-vouu56rr	19	5	as	as	IN
cord-304485-vouu56rr	19	6	vector	vector	NN
cord-304485-vouu56rr	19	7	offers	offer	VBZ
cord-304485-vouu56rr	19	8	several	several	JJ
cord-304485-vouu56rr	19	9	advantages	advantage	NNS
cord-304485-vouu56rr	19	10	.	.	.
cord-304485-vouu56rr	20	1	AAV	AAV	NNP
cord-304485-vouu56rr	20	2	can	can	MD
cord-304485-vouu56rr	20	3	not	not	RB
cord-304485-vouu56rr	20	4	replicate	replicate	VB
cord-304485-vouu56rr	20	5	in	in	IN
cord-304485-vouu56rr	20	6	humans	human	NNS
cord-304485-vouu56rr	20	7	,	,	,
cord-304485-vouu56rr	20	8	and	and	CC
cord-304485-vouu56rr	20	9	data	data	NN
cord-304485-vouu56rr	20	10	indicates	indicate	VBZ
cord-304485-vouu56rr	20	11	they	-PRON-	PRP
cord-304485-vouu56rr	20	12	do	do	VBP
cord-304485-vouu56rr	20	13	not	not	RB
cord-304485-vouu56rr	20	14	induce	induce	VB
cord-304485-vouu56rr	20	15	any	any	DT
cord-304485-vouu56rr	20	16	pathophysiology	pathophysiology	NN
cord-304485-vouu56rr	20	17	.	.	.
cord-304485-vouu56rr	21	1	They	-PRON-	PRP
cord-304485-vouu56rr	21	2	are	be	VBP
cord-304485-vouu56rr	21	3	easy	easy	JJ
cord-304485-vouu56rr	21	4	to	to	TO
cord-304485-vouu56rr	21	5	produce	produce	VB
cord-304485-vouu56rr	21	6	under	under	IN
cord-304485-vouu56rr	21	7	Good	Good	NNP
cord-304485-vouu56rr	21	8	Manufacturing	Manufacturing	NNP
cord-304485-vouu56rr	21	9	Practice	Practice	NNP
cord-304485-vouu56rr	21	10	standards	standard	NNS
cord-304485-vouu56rr	21	11	and	and	CC
cord-304485-vouu56rr	21	12	can	can	MD
cord-304485-vouu56rr	21	13	be	be	VB
cord-304485-vouu56rr	21	14	re	re	VBN
cord-304485-vouu56rr	21	15	-	-	VBN
cord-304485-vouu56rr	21	16	administered	administer	VBN
cord-304485-vouu56rr	21	17	if	if	IN
cord-304485-vouu56rr	21	18	needed	need	VBN
cord-304485-vouu56rr	21	19	.	.	.
cord-304485-vouu56rr	22	1	Of	of	IN
cord-304485-vouu56rr	22	2	note	note	NN
cord-304485-vouu56rr	22	3	,	,	,
cord-304485-vouu56rr	22	4	AAV	AAV	NNP
cord-304485-vouu56rr	22	5	has	have	VBZ
cord-304485-vouu56rr	22	6	been	be	VBN
cord-304485-vouu56rr	22	7	already	already	RB
cord-304485-vouu56rr	22	8	tested	test	VBN
cord-304485-vouu56rr	22	9	to	to	TO
cord-304485-vouu56rr	22	10	express	express	VB
cord-304485-vouu56rr	22	11	influenza	influenza	NN
cord-304485-vouu56rr	22	12	antigens	antigen	NNS
cord-304485-vouu56rr	22	13	and	and	CC
cord-304485-vouu56rr	22	14	showed	show	VBD
cord-304485-vouu56rr	22	15	to	to	TO
cord-304485-vouu56rr	22	16	confer	confer	VB
cord-304485-vouu56rr	22	17	protection	protection	NN
cord-304485-vouu56rr	22	18	(	(	-LRB-
cord-304485-vouu56rr	22	19	Lin	Lin	NNP
cord-304485-vouu56rr	22	20	et	et	NNP
cord-304485-vouu56rr	22	21	al	al	NNP
cord-304485-vouu56rr	22	22	,	,	,
cord-304485-vouu56rr	22	23	2009	2009	CD
cord-304485-vouu56rr	22	24	;	;	:
cord-304485-vouu56rr	22	25	Sipo	Sipo	NNP
cord-304485-vouu56rr	22	26	et	et	FW
cord-304485-vouu56rr	22	27	al	al	NNP
cord-304485-vouu56rr	22	28	,	,	,
cord-304485-vouu56rr	22	29	2011	2011	CD
cord-304485-vouu56rr	22	30	;	;	:
cord-304485-vouu56rr	22	31	Xin	Xin	NNP
cord-304485-vouu56rr	22	32	et	et	NNP
cord-304485-vouu56rr	22	33	al	al	NNP
cord-304485-vouu56rr	22	34	,	,	,
cord-304485-vouu56rr	22	35	2001	2001	CD
cord-304485-vouu56rr	22	36	)	)	-RRB-
cord-304485-vouu56rr	22	37	.	.	.
cord-304485-vouu56rr	23	1	Demminger	Demminger	NNP
cord-304485-vouu56rr	23	2	and	and	CC
cord-304485-vouu56rr	23	3	colleagues	colleague	NNS
cord-304485-vouu56rr	23	4	developed	develop	VBD
cord-304485-vouu56rr	23	5	AAV	AAV	NNP
cord-304485-vouu56rr	23	6	vectors	vector	NNS
cord-304485-vouu56rr	23	7	expressing	express	VBG
cord-304485-vouu56rr	23	8	wild	wild	JJ
cord-304485-vouu56rr	23	9	-	-	HYPH
cord-304485-vouu56rr	23	10	type	type	NN
cord-304485-vouu56rr	23	11	HA	HA	NNP
cord-304485-vouu56rr	23	12	,	,	,
cord-304485-vouu56rr	23	13	the	the	DT
cord-304485-vouu56rr	23	14	surface	surface	NN
cord-304485-vouu56rr	23	15	exposed	expose	VBN
cord-304485-vouu56rr	23	16	neuraminidase	neuraminidase	NN
cord-304485-vouu56rr	23	17	(	(	-LRB-
cord-304485-vouu56rr	23	18	NA	NA	NNP
cord-304485-vouu56rr	23	19	)	)	-RRB-
cord-304485-vouu56rr	23	20	,	,	,
cord-304485-vouu56rr	23	21	or	or	CC
cord-304485-vouu56rr	23	22	chimeric	chimeric	JJ
cord-304485-vouu56rr	23	23	HA	HA	NNP
cord-304485-vouu56rr	23	24	(	(	-LRB-
cord-304485-vouu56rr	23	25	cHA	cha	NN
cord-304485-vouu56rr	23	26	)	)	-RRB-
cord-304485-vouu56rr	23	27	containing	contain	VBG
cord-304485-vouu56rr	23	28	head	head	NN
cord-304485-vouu56rr	23	29	regions	region	NNS
cord-304485-vouu56rr	23	30	from	from	IN
cord-304485-vouu56rr	23	31	influenza	influenza	NN
cord-304485-vouu56rr	23	32	A	a	DT
cord-304485-vouu56rr	23	33	virus	virus	NN
cord-304485-vouu56rr	23	34	subtypes	subtype	NNS
cord-304485-vouu56rr	23	35	,	,	,
cord-304485-vouu56rr	23	36	or	or	CC
cord-304485-vouu56rr	23	37	HA	HA	NNP
cord-304485-vouu56rr	23	38	headless	headless	JJ
cord-304485-vouu56rr	23	39	constructs	construct	NNS
cord-304485-vouu56rr	23	40	.	.	.
cord-304485-vouu56rr	24	1	Constructs	construct	NNS
cord-304485-vouu56rr	24	2	were	be	VBD
cord-304485-vouu56rr	24	3	based	base	VBN
cord-304485-vouu56rr	24	4	on	on	IN
cord-304485-vouu56rr	24	5	proteins	protein	NNS
cord-304485-vouu56rr	24	6	encoded	encode	VBN
cord-304485-vouu56rr	24	7	by	by	IN
cord-304485-vouu56rr	24	8	the	the	DT
cord-304485-vouu56rr	24	9	pandemic	pandemic	NN
cord-304485-vouu56rr	24	10	influenza	influenza	NN
cord-304485-vouu56rr	24	11	virus	virus	NN
cord-304485-vouu56rr	24	12	A	a	NN
cord-304485-vouu56rr	24	13	/	/	SYM
cord-304485-vouu56rr	24	14	California/7/2009	california/7/2009	NN
cord-304485-vouu56rr	24	15	(	(	-LRB-
cord-304485-vouu56rr	24	16	H1N1	H1N1	NNP
cord-304485-vouu56rr	24	17	)	)	-RRB-
cord-304485-vouu56rr	24	18	pdm	pdm	NNP
cord-304485-vouu56rr	24	19	(	(	-LRB-
cord-304485-vouu56rr	24	20	Cal/7/9	Cal/7/9	NNP
cord-304485-vouu56rr	24	21	)	)	-RRB-
cord-304485-vouu56rr	24	22	.	.	.
cord-304485-vouu56rr	25	1	Control	control	NN
cord-304485-vouu56rr	25	2	assays	assay	NNS
cord-304485-vouu56rr	25	3	confirmed	confirm	VBD
cord-304485-vouu56rr	25	4	the	the	DT
cord-304485-vouu56rr	25	5	robust	robust	JJ
cord-304485-vouu56rr	25	6	expression	expression	NN
cord-304485-vouu56rr	25	7	of	of	IN
cord-304485-vouu56rr	25	8	all	all	DT
cord-304485-vouu56rr	25	9	antigens	antigen	NNS
cord-304485-vouu56rr	25	10	.	.	.
cord-304485-vouu56rr	26	1	Next	next	RB
cord-304485-vouu56rr	26	2	,	,	,
cord-304485-vouu56rr	26	3	they	-PRON-	PRP
cord-304485-vouu56rr	26	4	assessed	assess	VBD
cord-304485-vouu56rr	26	5	the	the	DT
cord-304485-vouu56rr	26	6	immunogenicity	immunogenicity	NN
cord-304485-vouu56rr	26	7	in	in	IN
cord-304485-vouu56rr	26	8	mice	mouse	NNS
cord-304485-vouu56rr	26	9	challenged	challenge	VBN
cord-304485-vouu56rr	26	10	intranasally	intranasally	RB
cord-304485-vouu56rr	26	11	testing	test	VBG
cord-304485-vouu56rr	26	12	side	side	NN
cord-304485-vouu56rr	26	13	-	-	HYPH
cord-304485-vouu56rr	26	14	by	by	IN
cord-304485-vouu56rr	26	15	-	-	HYPH
cord-304485-vouu56rr	26	16	side	side	NN
cord-304485-vouu56rr	26	17	empty	empty	JJ
cord-304485-vouu56rr	26	18	AAV	AAV	NNP
cord-304485-vouu56rr	26	19	vector	vector	NN
cord-304485-vouu56rr	26	20	(	(	-LRB-
cord-304485-vouu56rr	26	21	expressing	express	VBG
cord-304485-vouu56rr	26	22	GFP	GFP	NNP
cord-304485-vouu56rr	26	23	)	)	-RRB-
cord-304485-vouu56rr	26	24	and	and	CC
cord-304485-vouu56rr	26	25	whole	whole	RB
cord-304485-vouu56rr	26	26	-	-	HYPH
cord-304485-vouu56rr	26	27	inactivated	inactivate	VBN
cord-304485-vouu56rr	26	28	virus	virus	NN
cord-304485-vouu56rr	26	29	(	(	-LRB-
cord-304485-vouu56rr	26	30	WIV	WIV	NNP
cord-304485-vouu56rr	26	31	)	)	-RRB-
cord-304485-vouu56rr	26	32	as	as	IN
cord-304485-vouu56rr	26	33	controls	control	NNS
cord-304485-vouu56rr	26	34	.	.	.
cord-304485-vouu56rr	27	1	As	as	IN
cord-304485-vouu56rr	27	2	expected	expect	VBN
cord-304485-vouu56rr	27	3	,	,	,
cord-304485-vouu56rr	27	4	all	all	DT
cord-304485-vouu56rr	27	5	AAV	AAV	NNP
cord-304485-vouu56rr	27	6	constructs	construct	NNS
cord-304485-vouu56rr	27	7	expressing	express	VBG
cord-304485-vouu56rr	27	8	influenza	influenza	NN
cord-304485-vouu56rr	27	9	antigens	antigen	NNS
cord-304485-vouu56rr	27	10	did	do	VBD
cord-304485-vouu56rr	27	11	elicit	elicit	VB
cord-304485-vouu56rr	27	12	reactive	reactive	JJ
cord-304485-vouu56rr	27	13	antibodies	antibody	NNS
cord-304485-vouu56rr	27	14	that	that	WDT
cord-304485-vouu56rr	27	15	correlated	correlate	VBD
cord-304485-vouu56rr	27	16	with	with	IN
cord-304485-vouu56rr	27	17	the	the	DT
cord-304485-vouu56rr	27	18	total	total	JJ
cord-304485-vouu56rr	27	19	serum	serum	NN
cord-304485-vouu56rr	27	20	IgG	igg	NN
cord-304485-vouu56rr	27	21	titers	titer	NNS
cord-304485-vouu56rr	27	22	.	.	.
cord-304485-vouu56rr	28	1	Interestingly	interestingly	RB
cord-304485-vouu56rr	28	2	,	,	,
cord-304485-vouu56rr	28	3	AAV	AAV	NNP
cord-304485-vouu56rr	28	4	vectors	vector	NNS
cord-304485-vouu56rr	28	5	induced	induce	VBD
cord-304485-vouu56rr	28	6	antibodies	antibody	NNS
cord-304485-vouu56rr	28	7	against	against	IN
cord-304485-vouu56rr	28	8	a	a	DT
cord-304485-vouu56rr	28	9	panel	panel	NN
cord-304485-vouu56rr	28	10	of	of	IN
cord-304485-vouu56rr	28	11	different	different	JJ
cord-304485-vouu56rr	28	12	influenza	influenza	NN
cord-304485-vouu56rr	28	13	viruses	virus	NNS
cord-304485-vouu56rr	28	14	.	.	.
cord-304485-vouu56rr	29	1	Somewhat	somewhat	RB
cord-304485-vouu56rr	29	2	unexpectedly	unexpectedly	RB
cord-304485-vouu56rr	29	3	,	,	,
cord-304485-vouu56rr	29	4	WIV	WIV	NNP
cord-304485-vouu56rr	29	5	vaccination	vaccination	NN
cord-304485-vouu56rr	29	6	also	also	RB
cord-304485-vouu56rr	29	7	elicited	elicit	VBD
cord-304485-vouu56rr	29	8	broadly	broadly	RB
cord-304485-vouu56rr	29	9	reactive	reactive	JJ
cord-304485-vouu56rr	29	10	antibodies	antibody	NNS
cord-304485-vouu56rr	29	11	.	.	.
cord-304485-vouu56rr	30	1	Interestingly	interestingly	RB
cord-304485-vouu56rr	30	2	,	,	,
cord-304485-vouu56rr	30	3	neutralizing	neutralize	VBG
cord-304485-vouu56rr	30	4	antibodies	antibody	NNS
cord-304485-vouu56rr	30	5	were	be	VBD
cord-304485-vouu56rr	30	6	found	find	VBN
cord-304485-vouu56rr	30	7	only	only	RB
cord-304485-vouu56rr	30	8	in	in	IN
cord-304485-vouu56rr	30	9	the	the	DT
cord-304485-vouu56rr	30	10	sera	sera	NNP
cord-304485-vouu56rr	30	11	of	of	IN
cord-304485-vouu56rr	30	12	mice	mouse	NNS
cord-304485-vouu56rr	30	13	challenged	challenge	VBD
cord-304485-vouu56rr	30	14	with	with	IN
cord-304485-vouu56rr	30	15	AAV	AAV	NNP
cord-304485-vouu56rr	30	16	containing	contain	VBG
cord-304485-vouu56rr	30	17	HA	HA	NNP
cord-304485-vouu56rr	30	18	,	,	,
cord-304485-vouu56rr	30	19	or	or	CC
cord-304485-vouu56rr	30	20	cHA	cha	NN
cord-304485-vouu56rr	30	21	,	,	,
cord-304485-vouu56rr	30	22	and	and	CC
cord-304485-vouu56rr	30	23	these	these	DT
cord-304485-vouu56rr	30	24	antibodies	antibody	NNS
cord-304485-vouu56rr	30	25	were	be	VBD
cord-304485-vouu56rr	30	26	specific	specific	JJ
cord-304485-vouu56rr	30	27	for	for	IN
cord-304485-vouu56rr	30	28	the	the	DT
cord-304485-vouu56rr	30	29	virus	virus	NN
cord-304485-vouu56rr	30	30	used	use	VBN
cord-304485-vouu56rr	30	31	for	for	IN
cord-304485-vouu56rr	30	32	prime	prime	JJ
cord-304485-vouu56rr	30	33	immunization	immunization	NN
cord-304485-vouu56rr	30	34	.	.	.
cord-304485-vouu56rr	31	1	Of	of	IN
cord-304485-vouu56rr	31	2	significant	significant	JJ
cord-304485-vouu56rr	31	3	therapeutic	therapeutic	JJ
cord-304485-vouu56rr	31	4	relevance	relevance	NN
cord-304485-vouu56rr	31	5	,	,	,
cord-304485-vouu56rr	31	6	authors	author	NNS
cord-304485-vouu56rr	31	7	demonstrated	demonstrate	VBD
cord-304485-vouu56rr	31	8	that	that	IN
cord-304485-vouu56rr	31	9	AAV	AAV	NNP
cord-304485-vouu56rr	31	10	vector	vector	NN
cord-304485-vouu56rr	31	11	vaccination	vaccination	NN
cord-304485-vouu56rr	31	12	induced	induce	VBN
cord-304485-vouu56rr	31	13	strong	strong	JJ
cord-304485-vouu56rr	31	14	Fc	Fc	NNP
cord-304485-vouu56rr	31	15	-	-	HYPH
cord-304485-vouu56rr	31	16	activating	activate	VBG
cord-304485-vouu56rr	31	17	antibody	antibody	NN
cord-304485-vouu56rr	31	18	response	response	NN
cord-304485-vouu56rr	31	19	against	against	IN
cord-304485-vouu56rr	31	20	Cal/7/9	Cal/7/9	NNP
cord-304485-vouu56rr	31	21	but	but	CC
cord-304485-vouu56rr	31	22	also	also	RB
cord-304485-vouu56rr	31	23	against	against	IN
cord-304485-vouu56rr	31	24	the	the	DT
cord-304485-vouu56rr	31	25	mouse	mouse	NN
cord-304485-vouu56rr	31	26	-	-	HYPH
cord-304485-vouu56rr	31	27	adapted	adapt	VBN
cord-304485-vouu56rr	31	28	heterologous	heterologous	NNP
cord-304485-vouu56rr	31	29	influenza	influenza	NN
cord-304485-vouu56rr	31	30	virus	virus	NN
cord-304485-vouu56rr	31	31	PR8	PR8	NNP
cord-304485-vouu56rr	31	32	.	.	.
cord-304485-vouu56rr	32	1	These	these	DT
cord-304485-vouu56rr	32	2	positive	positive	JJ
cord-304485-vouu56rr	32	3	results	result	NNS
cord-304485-vouu56rr	32	4	encouraged	encourage	VBD
cord-304485-vouu56rr	32	5	authors	author	NNS
cord-304485-vouu56rr	32	6	to	to	TO
cord-304485-vouu56rr	32	7	test	test	VB
cord-304485-vouu56rr	32	8	whether	whether	IN
cord-304485-vouu56rr	32	9	AAV	AAV	NNP
cord-304485-vouu56rr	32	10	vectors	vector	NNS
cord-304485-vouu56rr	32	11	do	do	VBP
cord-304485-vouu56rr	32	12	protect	protect	VB
cord-304485-vouu56rr	32	13	mice	mouse	NNS
cord-304485-vouu56rr	32	14	from	from	IN
cord-304485-vouu56rr	32	15	homologous	homologous	JJ
cord-304485-vouu56rr	32	16	(	(	-LRB-
cord-304485-vouu56rr	32	17	Cal/7/9	Cal/7/9	NNP
cord-304485-vouu56rr	32	18	)	)	-RRB-
cord-304485-vouu56rr	32	19	and	and	CC
cord-304485-vouu56rr	32	20	heterologous	heterologous	NNP
cord-304485-vouu56rr	32	21	(	(	-LRB-
cord-304485-vouu56rr	32	22	PR8	PR8	NNP
cord-304485-vouu56rr	32	23	)	)	-RRB-
cord-304485-vouu56rr	32	24	challenges	challenge	NNS
cord-304485-vouu56rr	32	25	.	.	.
cord-304485-vouu56rr	33	1	Although	although	IN
cord-304485-vouu56rr	33	2	the	the	DT
cord-304485-vouu56rr	33	3	mouse	mouse	NN
cord-304485-vouu56rr	33	4	model	model	NN
cord-304485-vouu56rr	33	5	has	have	VBZ
cord-304485-vouu56rr	33	6	its	-PRON-	PRP$
cord-304485-vouu56rr	33	7	limitations	limitation	NNS
cord-304485-vouu56rr	33	8	in	in	IN
cord-304485-vouu56rr	33	9	terms	term	NNS
cord-304485-vouu56rr	33	10	of	of	IN
cord-304485-vouu56rr	33	11	translational	translational	JJ
cord-304485-vouu56rr	33	12	potential	potential	NN
cord-304485-vouu56rr	33	13	,	,	,
cord-304485-vouu56rr	33	14	it	-PRON-	PRP
cord-304485-vouu56rr	33	15	offers	offer	VBZ
cord-304485-vouu56rr	33	16	the	the	DT
cord-304485-vouu56rr	33	17	opportunity	opportunity	NN
cord-304485-vouu56rr	33	18	to	to	TO
cord-304485-vouu56rr	33	19	obtain	obtain	VB
cord-304485-vouu56rr	33	20	first	first	JJ
cord-304485-vouu56rr	33	21	proof	proof	NN
cord-304485-vouu56rr	33	22	-	-	HYPH
cord-304485-vouu56rr	33	23	of	of	IN
cord-304485-vouu56rr	33	24	-	-	HYPH
cord-304485-vouu56rr	33	25	concept	concept	NN
cord-304485-vouu56rr	33	26	information	information	NN
cord-304485-vouu56rr	33	27	.	.	.
cord-304485-vouu56rr	34	1	As	as	IN
cord-304485-vouu56rr	34	2	read	read	NN
cord-304485-vouu56rr	34	3	-	-	HYPH
cord-304485-vouu56rr	34	4	outs	out	NNS
cord-304485-vouu56rr	34	5	of	of	IN
cord-304485-vouu56rr	34	6	infection	infection	NN
cord-304485-vouu56rr	34	7	,	,	,
cord-304485-vouu56rr	34	8	Demminger	Demminger	NNP
cord-304485-vouu56rr	34	9	and	and	CC
cord-304485-vouu56rr	34	10	coworkers	coworker	NNS
cord-304485-vouu56rr	34	11	used	use	VBD
cord-304485-vouu56rr	34	12	weight	weight	NN
cord-304485-vouu56rr	34	13	loss	loss	NN
cord-304485-vouu56rr	34	14	and	and	CC
cord-304485-vouu56rr	34	15	survival	survival	NN
cord-304485-vouu56rr	34	16	of	of	IN
cord-304485-vouu56rr	34	17	mice	mouse	NNS
cord-304485-vouu56rr	34	18	over	over	IN
cord-304485-vouu56rr	34	19	a	a	DT
cord-304485-vouu56rr	34	20	14-day	14-day	CD
cord-304485-vouu56rr	34	21	period	period	NN
cord-304485-vouu56rr	34	22	.	.	.
cord-304485-vouu56rr	35	1	Mice	mouse	NNS
cord-304485-vouu56rr	35	2	vaccinated	vaccinate	VBN
cord-304485-vouu56rr	35	3	with	with	IN
cord-304485-vouu56rr	35	4	the	the	DT
cord-304485-vouu56rr	35	5	AAV	AAV	NNP
cord-304485-vouu56rr	35	6	construct	construct	VB
cord-304485-vouu56rr	35	7	were	be	VBD
cord-304485-vouu56rr	35	8	protected	protect	VBN
cord-304485-vouu56rr	35	9	,	,	,
cord-304485-vouu56rr	35	10	and	and	CC
cord-304485-vouu56rr	35	11	preliminary	preliminary	JJ
cord-304485-vouu56rr	35	12	data	datum	NNS
cord-304485-vouu56rr	35	13	suggest	suggest	VBP
cord-304485-vouu56rr	35	14	that	that	IN
cord-304485-vouu56rr	35	15	three	three	CD
cord-304485-vouu56rr	35	16	doses	dose	NNS
cord-304485-vouu56rr	35	17	of	of	IN
cord-304485-vouu56rr	35	18	the	the	DT
cord-304485-vouu56rr	35	19	vaccine	vaccine	NN
cord-304485-vouu56rr	35	20	were	be	VBD
cord-304485-vouu56rr	35	21	better	well	JJR
cord-304485-vouu56rr	35	22	than	than	IN
cord-304485-vouu56rr	35	23	two	two	CD
cord-304485-vouu56rr	35	24	doses	dose	NNS
cord-304485-vouu56rr	35	25	.	.	.
cord-304485-vouu56rr	36	1	Although	although	IN
cord-304485-vouu56rr	36	2	these	these	DT
cord-304485-vouu56rr	36	3	findings	finding	NNS
cord-304485-vouu56rr	36	4	are	be	VBP
cord-304485-vouu56rr	36	5	sound	sound	JJ
cord-304485-vouu56rr	36	6	,	,	,
cord-304485-vouu56rr	36	7	it	-PRON-	PRP
cord-304485-vouu56rr	36	8	is	be	VBZ
cord-304485-vouu56rr	36	9	important	important	JJ
cord-304485-vouu56rr	36	10	to	to	TO
cord-304485-vouu56rr	36	11	note	note	VB
cord-304485-vouu56rr	36	12	that	that	DT
cord-304485-vouu56rr	36	13	determination	determination	NN
cord-304485-vouu56rr	36	14	of	of	IN
cord-304485-vouu56rr	36	15	viral	viral	JJ
cord-304485-vouu56rr	36	16	titers	titer	NNS
cord-304485-vouu56rr	36	17	in	in	IN
cord-304485-vouu56rr	36	18	the	the	DT
cord-304485-vouu56rr	36	19	tissues	tissue	NNS
cord-304485-vouu56rr	36	20	over	over	IN
cord-304485-vouu56rr	36	21	time	time	NN
cord-304485-vouu56rr	36	22	should	should	MD
cord-304485-vouu56rr	36	23	be	be	VB
cord-304485-vouu56rr	36	24	determined	determine	VBN
cord-304485-vouu56rr	36	25	to	to	TO
cord-304485-vouu56rr	36	26	solidify	solidify	VB
cord-304485-vouu56rr	36	27	the	the	DT
cord-304485-vouu56rr	36	28	read	read	NN
cord-304485-vouu56rr	36	29	-	-	HYPH
cord-304485-vouu56rr	36	30	outs	out	NNS
cord-304485-vouu56rr	36	31	based	base	VBN
cord-304485-vouu56rr	36	32	on	on	IN
cord-304485-vouu56rr	36	33	animal	animal	NN
cord-304485-vouu56rr	36	34	behavior	behavior	NN
cord-304485-vouu56rr	36	35	,	,	,
cord-304485-vouu56rr	36	36	clinical	clinical	JJ
cord-304485-vouu56rr	36	37	parameters	parameter	NNS
cord-304485-vouu56rr	36	38	,	,	,
cord-304485-vouu56rr	36	39	and/or	and/or	CC
cord-304485-vouu56rr	36	40	survival	survival	NN
cord-304485-vouu56rr	36	41	.	.	.
cord-304485-vouu56rr	37	1	Some	some	DT
cord-304485-vouu56rr	37	2	control	control	NN
cord-304485-vouu56rr	37	3	experiments	experiment	NNS
cord-304485-vouu56rr	37	4	revealed	reveal	VBD
cord-304485-vouu56rr	37	5	a	a	DT
cord-304485-vouu56rr	37	6	reduction	reduction	NN
cord-304485-vouu56rr	37	7	in	in	IN
cord-304485-vouu56rr	37	8	viral	viral	JJ
cord-304485-vouu56rr	37	9	titers	titer	NNS
cord-304485-vouu56rr	37	10	in	in	IN
cord-304485-vouu56rr	37	11	vaccinated	vaccinated	JJ
cord-304485-vouu56rr	37	12	animals	animal	NNS
cord-304485-vouu56rr	37	13	.	.	.
cord-304485-vouu56rr	38	1	In	in	IN
cord-304485-vouu56rr	38	2	a	a	DT
cord-304485-vouu56rr	38	3	remarkable	remarkable	JJ
cord-304485-vouu56rr	38	4	tour	tour	NN
cord-304485-vouu56rr	38	5	de	de	IN
cord-304485-vouu56rr	38	6	force	force	NN
cord-304485-vouu56rr	38	7	,	,	,
cord-304485-vouu56rr	38	8	authors	author	NNS
cord-304485-vouu56rr	38	9	went	go	VBD
cord-304485-vouu56rr	38	10	on	on	RP
cord-304485-vouu56rr	38	11	to	to	TO
cord-304485-vouu56rr	38	12	assess	assess	VB
cord-304485-vouu56rr	38	13	the	the	DT
cord-304485-vouu56rr	38	14	protective	protective	JJ
cord-304485-vouu56rr	38	15	efficacy	efficacy	NN
cord-304485-vouu56rr	38	16	of	of	IN
cord-304485-vouu56rr	38	17	the	the	DT
cord-304485-vouu56rr	38	18	AAV	AAV	NNP
cord-304485-vouu56rr	38	19	vectors	vector	NNS
cord-304485-vouu56rr	38	20	in	in	IN
cord-304485-vouu56rr	38	21	ferrets	ferret	NNS
cord-304485-vouu56rr	38	22	.	.	.
cord-304485-vouu56rr	39	1	This	this	DT
cord-304485-vouu56rr	39	2	animal	animal	NN
cord-304485-vouu56rr	39	3	model	model	NN
cord-304485-vouu56rr	39	4	reproduces	reproduce	VBZ
cord-304485-vouu56rr	39	5	very	very	RB
cord-304485-vouu56rr	39	6	closely	closely	RB
cord-304485-vouu56rr	39	7	the	the	DT
cord-304485-vouu56rr	39	8	course	course	NN
cord-304485-vouu56rr	39	9	of	of	IN
cord-304485-vouu56rr	39	10	human	human	JJ
cord-304485-vouu56rr	39	11	influenza	influenza	NN
cord-304485-vouu56rr	39	12	.	.	.
cord-304485-vouu56rr	40	1	In	in	IN
cord-304485-vouu56rr	40	2	these	these	DT
cord-304485-vouu56rr	40	3	experiments	experiment	NNS
cord-304485-vouu56rr	40	4	,	,	,
cord-304485-vouu56rr	40	5	authors	author	NNS
cord-304485-vouu56rr	40	6	also	also	RB
cord-304485-vouu56rr	40	7	introduce	introduce	VBP
cord-304485-vouu56rr	40	8	a	a	DT
cord-304485-vouu56rr	40	9	group	group	NN
cord-304485-vouu56rr	40	10	immunized	immunize	VBN
cord-304485-vouu56rr	40	11	with	with	IN
cord-304485-vouu56rr	40	12	a	a	DT
cord-304485-vouu56rr	40	13	commercial	commercial	JJ
cord-304485-vouu56rr	40	14	quadrivalent	quadrivalent	NN
cord-304485-vouu56rr	40	15	influenza	influenza	NN
cord-304485-vouu56rr	40	16	vaccine	vaccine	NN
cord-304485-vouu56rr	40	17	of	of	IN
cord-304485-vouu56rr	40	18	season	season	NN
cord-304485-vouu56rr	40	19	2017/18	2017/18	CD
cord-304485-vouu56rr	40	20	.	.	.
cord-304485-vouu56rr	41	1	Animals	animal	NNS
cord-304485-vouu56rr	41	2	were	be	VBD
cord-304485-vouu56rr	41	3	vaccinated	vaccinate	VBN
cord-304485-vouu56rr	41	4	intranasally	intranasally	RB
cord-304485-vouu56rr	41	5	three	three	CD
cord-304485-vouu56rr	41	6	times	time	NNS
cord-304485-vouu56rr	41	7	in	in	IN
cord-304485-vouu56rr	41	8	4week	4week	CD
cord-304485-vouu56rr	41	9	interval	interval	NN
cord-304485-vouu56rr	41	10	whereas	whereas	IN
cord-304485-vouu56rr	41	11	the	the	DT
cord-304485-vouu56rr	41	12	control	control	NN
cord-304485-vouu56rr	41	13	group	group	NN
cord-304485-vouu56rr	41	14	immunized	immunize	VBN
cord-304485-vouu56rr	41	15	with	with	IN
cord-304485-vouu56rr	41	16	the	the	DT
cord-304485-vouu56rr	41	17	commercial	commercial	JJ
cord-304485-vouu56rr	41	18	vaccine	vaccine	NN
cord-304485-vouu56rr	41	19	were	be	VBD
cord-304485-vouu56rr	41	20	given	give	VBN
cord-304485-vouu56rr	41	21	two	two	CD
cord-304485-vouu56rr	41	22	doses	dose	NNS
cord-304485-vouu56rr	41	23	by	by	IN
cord-304485-vouu56rr	41	24	the	the	DT
cord-304485-vouu56rr	41	25	intramuscular	intramuscular	JJ
cord-304485-vouu56rr	41	26	route	route	NN
cord-304485-vouu56rr	41	27	.	.	.
cord-304485-vouu56rr	42	1	It	-PRON-	PRP
cord-304485-vouu56rr	42	2	can	can	MD
cord-304485-vouu56rr	42	3	be	be	VB
cord-304485-vouu56rr	42	4	argued	argue	VBN
cord-304485-vouu56rr	42	5	that	that	IN
cord-304485-vouu56rr	42	6	the	the	DT
cord-304485-vouu56rr	42	7	different	different	JJ
cord-304485-vouu56rr	42	8	experimental	experimental	JJ
cord-304485-vouu56rr	42	9	regime	regime	NN
cord-304485-vouu56rr	42	10	of	of	IN
cord-304485-vouu56rr	42	11	the	the	DT
cord-304485-vouu56rr	42	12	groups	group	NNS
cord-304485-vouu56rr	42	13	is	be	VBZ
cord-304485-vouu56rr	42	14	not	not	RB
cord-304485-vouu56rr	42	15	suitable	suitable	JJ
cord-304485-vouu56rr	42	16	for	for	IN
cord-304485-vouu56rr	42	17	a	a	DT
cord-304485-vouu56rr	42	18	comparison	comparison	NN
cord-304485-vouu56rr	42	19	between	between	IN
cord-304485-vouu56rr	42	20	the	the	DT
cord-304485-vouu56rr	42	21	different	different	JJ
cord-304485-vouu56rr	42	22	vaccine	vaccine	NN
cord-304485-vouu56rr	42	23	formulations	formulation	NNS
cord-304485-vouu56rr	42	24	.	.	.
cord-304485-vouu56rr	43	1	However	however	RB
cord-304485-vouu56rr	43	2	,	,	,
cord-304485-vouu56rr	43	3	the	the	DT
cord-304485-vouu56rr	43	4	aim	aim	NN
cord-304485-vouu56rr	43	5	of	of	IN
cord-304485-vouu56rr	43	6	this	this	DT
cord-304485-vouu56rr	43	7	work	work	NN
cord-304485-vouu56rr	43	8	was	be	VBD
cord-304485-vouu56rr	43	9	to	to	TO
cord-304485-vouu56rr	43	10	demonstrate	demonstrate	VB
cord-304485-vouu56rr	43	11	whether	whether	IN
cord-304485-vouu56rr	43	12	the	the	DT
cord-304485-vouu56rr	43	13	AAV	AAV	NNP
cord-304485-vouu56rr	43	14	vectors	vector	NNS
cord-304485-vouu56rr	43	15	do	do	VBP
cord-304485-vouu56rr	43	16	confer	confer	VB
cord-304485-vouu56rr	43	17	protection	protection	NN
cord-304485-vouu56rr	43	18	and	and	CC
cord-304485-vouu56rr	43	19	not	not	RB
cord-304485-vouu56rr	43	20	whether	whether	IN
cord-304485-vouu56rr	43	21	they	-PRON-	PRP
cord-304485-vouu56rr	43	22	are	be	VBP
cord-304485-vouu56rr	43	23	better	well	JJR
cord-304485-vouu56rr	43	24	than	than	IN
cord-304485-vouu56rr	43	25	the	the	DT
cord-304485-vouu56rr	43	26	commercial	commercial	JJ
cord-304485-vouu56rr	43	27	vaccine	vaccine	NN
cord-304485-vouu56rr	43	28	.	.	.
cord-304485-vouu56rr	44	1	In	in	IN
cord-304485-vouu56rr	44	2	a	a	DT
cord-304485-vouu56rr	44	3	3-day	3-day	JJ
cord-304485-vouu56rr	44	4	infection	infection	NN
cord-304485-vouu56rr	44	5	protocol	protocol	NN
cord-304485-vouu56rr	44	6	,	,	,
cord-304485-vouu56rr	44	7	ferrets	ferret	NNS
cord-304485-vouu56rr	44	8	vaccinated	vaccinate	VBN
cord-304485-vouu56rr	44	9	with	with	IN
cord-304485-vouu56rr	44	10	the	the	DT
cord-304485-vouu56rr	44	11	AAV	AAV	NNP
cord-304485-vouu56rr	44	12	vectors	vector	NNS
cord-304485-vouu56rr	44	13	showed	show	VBD
cord-304485-vouu56rr	44	14	clear	clear	JJ
cord-304485-vouu56rr	44	15	signs	sign	NNS
cord-304485-vouu56rr	44	16	of	of	IN
cord-304485-vouu56rr	44	17	recovery	recovery	NN
cord-304485-vouu56rr	44	18	assessing	assess	VBG
cord-304485-vouu56rr	44	19	serous	serous	JJ
cord-304485-vouu56rr	44	20	nasal	nasal	NN
cord-304485-vouu56rr	44	21	exudate	exudate	NN
cord-304485-vouu56rr	44	22	,	,	,
cord-304485-vouu56rr	44	23	congestion	congestion	NN
cord-304485-vouu56rr	44	24	,	,	,
cord-304485-vouu56rr	44	25	frequent	frequent	JJ
cord-304485-vouu56rr	44	26	sneezing	sneezing	NN
cord-304485-vouu56rr	44	27	,	,	,
cord-304485-vouu56rr	44	28	wheezing	wheeze	VBG
cord-304485-vouu56rr	44	29	,	,	,
cord-304485-vouu56rr	44	30	and	and	CC
cord-304485-vouu56rr	44	31	depression	depression	NN
cord-304485-vouu56rr	44	32	.	.	.
cord-304485-vouu56rr	45	1	Notably	notably	RB
cord-304485-vouu56rr	45	2	,	,	,
cord-304485-vouu56rr	45	3	only	only	RB
cord-304485-vouu56rr	45	4	in	in	IN
cord-304485-vouu56rr	45	5	those	those	DT
cord-304485-vouu56rr	45	6	ferrets	ferret	NNS
cord-304485-vouu56rr	45	7	vaccinated	vaccinate	VBN
cord-304485-vouu56rr	45	8	with	with	IN
cord-304485-vouu56rr	45	9	the	the	DT
cord-304485-vouu56rr	45	10	AAV	AAV	NNP
cord-304485-vouu56rr	45	11	-	-	HYPH
cord-304485-vouu56rr	45	12	HA	HA	NNP
cord-304485-vouu56rr	45	13	construct	construct	VB
cord-304485-vouu56rr	45	14	and	and	CC
cord-304485-vouu56rr	45	15	the	the	DT
cord-304485-vouu56rr	45	16	commercial	commercial	JJ
cord-304485-vouu56rr	45	17	vaccine	vaccine	NN
cord-304485-vouu56rr	45	18	was	be	VBD
cord-304485-vouu56rr	45	19	there	there	EX
cord-304485-vouu56rr	45	20	a	a	DT
cord-304485-vouu56rr	45	21	reduction	reduction	NN
cord-304485-vouu56rr	45	22	in	in	IN
cord-304485-vouu56rr	45	23	the	the	DT
cord-304485-vouu56rr	45	24	load	load	NN
cord-304485-vouu56rr	45	25	of	of	IN
cord-304485-vouu56rr	45	26	virus	virus	NN
cord-304485-vouu56rr	45	27	although	although	IN
cord-304485-vouu56rr	45	28	no	no	DT
cord-304485-vouu56rr	45	29	sterile	sterile	JJ
cord-304485-vouu56rr	45	30	immunity	immunity	NN
cord-304485-vouu56rr	45	31	was	be	VBD
cord-304485-vouu56rr	45	32	induced	induce	VBN
cord-304485-vouu56rr	45	33	.	.	.
cord-304485-vouu56rr	46	1	Virus	virus	NN
cord-304485-vouu56rr	46	2	clearance	clearance	NN
cord-304485-vouu56rr	46	3	was	be	VBD
cord-304485-vouu56rr	46	4	associated	associate	VBN
cord-304485-vouu56rr	46	5	with	with	IN
cord-304485-vouu56rr	46	6	a	a	DT
cord-304485-vouu56rr	46	7	significant	significant	JJ
cord-304485-vouu56rr	46	8	reduction	reduction	NN
cord-304485-vouu56rr	46	9	in	in	IN
cord-304485-vouu56rr	46	10	pathophysiology	pathophysiology	NN
cord-304485-vouu56rr	46	11	and	and	CC
cord-304485-vouu56rr	46	12	induction	induction	NN
cord-304485-vouu56rr	46	13	of	of	IN
cord-304485-vouu56rr	46	14	neutralizing	neutralize	VBG
cord-304485-vouu56rr	46	15	antibodies	antibody	NNS
cord-304485-vouu56rr	46	16	.	.	.
cord-304485-vouu56rr	47	1	This	this	DT
cord-304485-vouu56rr	47	2	elegant	elegant	JJ
cord-304485-vouu56rr	47	3	study	study	NN
cord-304485-vouu56rr	47	4	follows	follow	VBZ
cord-304485-vouu56rr	47	5	a	a	DT
cord-304485-vouu56rr	47	6	comprehensive	comprehensive	JJ
cord-304485-vouu56rr	47	7	design	design	NN
cord-304485-vouu56rr	47	8	from	from	IN
cord-304485-vouu56rr	47	9	in	in	IN
cord-304485-vouu56rr	47	10	vitro	vitro	FW
cord-304485-vouu56rr	47	11	characterization	characterization	NN
cord-304485-vouu56rr	47	12	of	of	IN
cord-304485-vouu56rr	47	13	the	the	DT
cord-304485-vouu56rr	47	14	AAV	AAV	NNP
cord-304485-vouu56rr	47	15	vectors	vector	NNS
cord-304485-vouu56rr	47	16	to	to	IN
cord-304485-vouu56rr	47	17	animal	animal	NN
cord-304485-vouu56rr	47	18	pre	pre	JJ
cord-304485-vouu56rr	47	19	-	-	JJ
cord-304485-vouu56rr	47	20	clinical	clinical	JJ
cord-304485-vouu56rr	47	21	studies	study	NNS
cord-304485-vouu56rr	47	22	probing	probe	VBG
cord-304485-vouu56rr	47	23	two	two	CD
cord-304485-vouu56rr	47	24	different	different	JJ
cord-304485-vouu56rr	47	25	research	research	NN
cord-304485-vouu56rr	47	26	models	model	NNS
cord-304485-vouu56rr	47	27	,	,	,
cord-304485-vouu56rr	47	28	one	one	CD
cord-304485-vouu56rr	47	29	of	of	IN
cord-304485-vouu56rr	47	30	them	-PRON-	PRP
cord-304485-vouu56rr	47	31	of	of	IN
cord-304485-vouu56rr	47	32	significant	significant	JJ
cord-304485-vouu56rr	47	33	translational	translational	JJ
cord-304485-vouu56rr	47	34	potential	potential	NN
cord-304485-vouu56rr	47	35	(	(	-LRB-
cord-304485-vouu56rr	47	36	Fig	Fig	NNP
cord-304485-vouu56rr	47	37	1	1	CD
cord-304485-vouu56rr	47	38	)	)	-RRB-
cord-304485-vouu56rr	47	39	.	.	.
cord-304485-vouu56rr	48	1	The	the	DT
cord-304485-vouu56rr	48	2	use	use	NN
cord-304485-vouu56rr	48	3	of	of	IN
cord-304485-vouu56rr	48	4	research	research	NN
cord-304485-vouu56rr	48	5	models	model	NNS
cord-304485-vouu56rr	48	6	approximating	approximate	VBG
cord-304485-vouu56rr	48	7	human	human	JJ
cord-304485-vouu56rr	48	8	disease	disease	NN
cord-304485-vouu56rr	48	9	,	,	,
cord-304485-vouu56rr	48	10	ferrets	ferret	NNS
cord-304485-vouu56rr	48	11	in	in	IN
cord-304485-vouu56rr	48	12	this	this	DT
cord-304485-vouu56rr	48	13	case	case	NN
cord-304485-vouu56rr	48	14	,	,	,
cord-304485-vouu56rr	48	15	should	should	MD
cord-304485-vouu56rr	48	16	be	be	VB
cord-304485-vouu56rr	48	17	a	a	DT
cord-304485-vouu56rr	48	18	golden	golden	JJ
cord-304485-vouu56rr	48	19	standard	standard	JJ
cord-304485-vouu56rr	48	20	approach	approach	NN
cord-304485-vouu56rr	48	21	in	in	IN
cord-304485-vouu56rr	48	22	any	any	DT
cord-304485-vouu56rr	48	23	work	work	NN
cord-304485-vouu56rr	48	24	focusing	focus	VBG
cord-304485-vouu56rr	48	25	on	on	IN
cord-304485-vouu56rr	48	26	vaccine	vaccine	NN
cord-304485-vouu56rr	48	27	development	development	NN
cord-304485-vouu56rr	48	28	.	.	.
cord-304485-vouu56rr	49	1	The	the	DT
cord-304485-vouu56rr	49	2	value	value	NN
cord-304485-vouu56rr	49	3	of	of	IN
cord-304485-vouu56rr	49	4	the	the	DT
cord-304485-vouu56rr	49	5	mouse	mouse	NN
cord-304485-vouu56rr	49	6	model	model	NN
cord-304485-vouu56rr	49	7	can	can	MD
cord-304485-vouu56rr	49	8	not	not	RB
cord-304485-vouu56rr	49	9	be	be	VB
cord-304485-vouu56rr	49	10	disregarded	disregard	VBN
cord-304485-vouu56rr	49	11	but	but	CC
cord-304485-vouu56rr	49	12	,	,	,
cord-304485-vouu56rr	49	13	certainly	certainly	RB
cord-304485-vouu56rr	49	14	,	,	,
cord-304485-vouu56rr	49	15	the	the	DT
cord-304485-vouu56rr	49	16	time	time	NN
cord-304485-vouu56rr	49	17	is	be	VBZ
cord-304485-vouu56rr	49	18	ripe	ripe	JJ
cord-304485-vouu56rr	49	19	to	to	TO
cord-304485-vouu56rr	49	20	probe	probe	VB
cord-304485-vouu56rr	49	21	models	model	NNS
cord-304485-vouu56rr	49	22	with	with	IN
cord-304485-vouu56rr	49	23	increasing	increase	VBG
cord-304485-vouu56rr	49	24	translational	translational	JJ
cord-304485-vouu56rr	49	25	value	value	NN
cord-304485-vouu56rr	49	26	.	.	.
cord-304485-vouu56rr	50	1	This	this	DT
cord-304485-vouu56rr	50	2	work	work	NN
cord-304485-vouu56rr	50	3	also	also	RB
cord-304485-vouu56rr	50	4	reinforces	reinforce	VBZ
cord-304485-vouu56rr	50	5	the	the	DT
cord-304485-vouu56rr	50	6	utility	utility	NN
cord-304485-vouu56rr	50	7	of	of	IN
cord-304485-vouu56rr	50	8	AAV	AAV	NNP
cord-304485-vouu56rr	50	9	vectors	vector	NNS
cord-304485-vouu56rr	50	10	as	as	IN
cord-304485-vouu56rr	50	11	platform	platform	NN
cord-304485-vouu56rr	50	12	to	to	TO
cord-304485-vouu56rr	50	13	develop	develop	VB
cord-304485-vouu56rr	50	14	vaccines	vaccine	NNS
cord-304485-vouu56rr	50	15	.	.	.
cord-304485-vouu56rr	51	1	AAV	AAV	NNP
cord-304485-vouu56rr	51	2	vectors	vector	NNS
cord-304485-vouu56rr	51	3	are	be	VBP
cord-304485-vouu56rr	51	4	already	already	RB
cord-304485-vouu56rr	51	5	approved	approve	VBN
cord-304485-vouu56rr	51	6	by	by	IN
cord-304485-vouu56rr	51	7	the	the	DT
cord-304485-vouu56rr	51	8	EMA	EMA	NNP
cord-304485-vouu56rr	51	9	and	and	CC
cord-304485-vouu56rr	51	10	FDA	FDA	NNP
cord-304485-vouu56rr	51	11	for	for	IN
cord-304485-vouu56rr	51	12	its	-PRON-	PRP$
cord-304485-vouu56rr	51	13	use	use	NN
cord-304485-vouu56rr	51	14	in	in	IN
cord-304485-vouu56rr	51	15	humans	human	NNS
cord-304485-vouu56rr	51	16	and	and	CC
cord-304485-vouu56rr	51	17	have	have	VBP
cord-304485-vouu56rr	51	18	been	be	VBN
cord-304485-vouu56rr	51	19	tested	test	VBN
cord-304485-vouu56rr	51	20	in	in	IN
cord-304485-vouu56rr	51	21	pre	pre	JJ
cord-304485-vouu56rr	51	22	-	-	JJ
cord-304485-vouu56rr	51	23	clinical	clinical	JJ
cord-304485-vouu56rr	51	24	immunization	immunization	NN
cord-304485-vouu56rr	51	25	studies	study	NNS
cord-304485-vouu56rr	51	26	against	against	IN
cord-304485-vouu56rr	51	27	infectious	infectious	JJ
cord-304485-vouu56rr	51	28	diseases	disease	NNS
cord-304485-vouu56rr	51	29	.	.	.
cord-304485-vouu56rr	52	1	Demminger	Demminger	NNP
cord-304485-vouu56rr	52	2	and	and	CC
cord-304485-vouu56rr	52	3	colleagues	colleague	NNS
cord-304485-vouu56rr	52	4	demonstrate	demonstrate	VBP
cord-304485-vouu56rr	52	5	that	that	IN
cord-304485-vouu56rr	52	6	they	-PRON-	PRP
cord-304485-vouu56rr	52	7	should	should	MD
cord-304485-vouu56rr	52	8	be	be	VB
cord-304485-vouu56rr	52	9	considered	consider	VBN
cord-304485-vouu56rr	52	10	as	as	IN
cord-304485-vouu56rr	52	11	a	a	DT
cord-304485-vouu56rr	52	12	valid	valid	JJ
cord-304485-vouu56rr	52	13	platform	platform	NN
cord-304485-vouu56rr	52	14	for	for	IN
cord-304485-vouu56rr	52	15	a	a	DT
cord-304485-vouu56rr	52	16	broadly	broadly	RB
cord-304485-vouu56rr	52	17	protective	protective	JJ
cord-304485-vouu56rr	52	18	influenza	influenza	NN
cord-304485-vouu56rr	52	19	vaccine	vaccine	NN
cord-304485-vouu56rr	52	20	.	.	.
cord-304485-vouu56rr	53	1	I	-PRON-	PRP
cord-304485-vouu56rr	53	2	anticipate	anticipate	VBP
cord-304485-vouu56rr	53	3	that	that	IN
cord-304485-vouu56rr	53	4	this	this	DT
cord-304485-vouu56rr	53	5	comprehensive	comprehensive	JJ
cord-304485-vouu56rr	53	6	work	work	NN
cord-304485-vouu56rr	53	7	will	will	MD
cord-304485-vouu56rr	53	8	lead	lead	VB
cord-304485-vouu56rr	53	9	to	to	IN
cord-304485-vouu56rr	53	10	significant	significant	JJ
cord-304485-vouu56rr	53	11	advances	advance	NNS
cord-304485-vouu56rr	53	12	in	in	IN
cord-304485-vouu56rr	53	13	our	-PRON-	PRP$
cord-304485-vouu56rr	53	14	quest	quest	NN
cord-304485-vouu56rr	53	15	to	to	TO
cord-304485-vouu56rr	53	16	develop	develop	VB
cord-304485-vouu56rr	53	17	effective	effective	JJ
cord-304485-vouu56rr	53	18	influenza	influenza	NN
cord-304485-vouu56rr	53	19	vaccines	vaccine	NNS
cord-304485-vouu56rr	53	20	and	and	CC
cord-304485-vouu56rr	53	21	may	may	MD
cord-304485-vouu56rr	53	22	result	result	VB
cord-304485-vouu56rr	53	23	in	in	IN
cord-304485-vouu56rr	53	24	similar	similar	JJ
cord-304485-vouu56rr	53	25	research	research	NN
cord-304485-vouu56rr	53	26	to	to	TO
cord-304485-vouu56rr	53	27	tackle	tackle	VB
cord-304485-vouu56rr	53	28	other	other	JJ
cord-304485-vouu56rr	53	29	infections	infection	NNS
cord-304485-vouu56rr	53	30	.	.	.
cord-304485-vouu56rr	54	1	I	-PRON-	PRP
cord-304485-vouu56rr	54	2	will	will	MD
cord-304485-vouu56rr	54	3	encourage	encourage	VB
cord-304485-vouu56rr	54	4	the	the	DT
cord-304485-vouu56rr	54	5	vaccinology	vaccinology	NN
cord-304485-vouu56rr	54	6	field	field	NN
cord-304485-vouu56rr	54	7	to	to	TO
cord-304485-vouu56rr	54	8	consider	consider	VB
cord-304485-vouu56rr	54	9	and	and	CC
cord-304485-vouu56rr	54	10	set	set	VB
cord-304485-vouu56rr	54	11	clear	clear	JJ
cord-304485-vouu56rr	54	12	parameters	parameter	NNS
cord-304485-vouu56rr	54	13	that	that	WDT
cord-304485-vouu56rr	54	14	should	should	MD
cord-304485-vouu56rr	54	15	be	be	VB
cord-304485-vouu56rr	54	16	determined	determine	VBN
cord-304485-vouu56rr	54	17	in	in	IN
cord-304485-vouu56rr	54	18	any	any	DT
cord-304485-vouu56rr	54	19	research	research	NN
cord-304485-vouu56rr	54	20	like	like	IN
cord-304485-vouu56rr	54	21	the	the	DT
cord-304485-vouu56rr	54	22	one	one	NN
cord-304485-vouu56rr	54	23	presented	present	VBN
cord-304485-vouu56rr	54	24	in	in	IN
cord-304485-vouu56rr	54	25	this	this	DT
cord-304485-vouu56rr	54	26	issue	issue	NN
cord-304485-vouu56rr	54	27	of	of	IN
cord-304485-vouu56rr	54	28	EMBO	EMBO	NNP
cord-304485-vouu56rr	54	29	Molecular	Molecular	NNP
cord-304485-vouu56rr	54	30	Medicine	Medicine	NNP
cord-304485-vouu56rr	54	31	(	(	-LRB-
cord-304485-vouu56rr	54	32	Demminger	Demminger	NNP
cord-304485-vouu56rr	54	33	et	et	FW
cord-304485-vouu56rr	54	34	al	al	NNP
cord-304485-vouu56rr	54	35	,	,	,
cord-304485-vouu56rr	54	36	2020	2020	CD
cord-304485-vouu56rr	54	37	)	)	-RRB-
cord-304485-vouu56rr	54	38	.	.	.
cord-304485-vouu56rr	55	1	From	from	IN
cord-304485-vouu56rr	55	2	clear	clear	JJ
cord-304485-vouu56rr	55	3	guidelines	guideline	NNS
cord-304485-vouu56rr	55	4	on	on	IN
cord-304485-vouu56rr	55	5	power	power	NN
cord-304485-vouu56rr	55	6	calculation	calculation	NN
cord-304485-vouu56rr	55	7	for	for	IN
cord-304485-vouu56rr	55	8	the	the	DT
cord-304485-vouu56rr	55	9	in	in	IN
cord-304485-vouu56rr	55	10	vivo	vivo	NN
cord-304485-vouu56rr	55	11	work	work	NN
cord-304485-vouu56rr	55	12	to	to	IN
cord-304485-vouu56rr	55	13	the	the	DT
cord-304485-vouu56rr	55	14	biological	biological	JJ
cord-304485-vouu56rr	55	15	read	read	NN
cord-304485-vouu56rr	55	16	-	-	HYPH
cord-304485-vouu56rr	55	17	outs	out	NNS
cord-304485-vouu56rr	55	18	that	that	WDT
cord-304485-vouu56rr	55	19	should	should	MD
cord-304485-vouu56rr	55	20	be	be	VB
cord-304485-vouu56rr	55	21	analyzed	analyze	VBN
cord-304485-vouu56rr	55	22	.	.	.
cord-304485-vouu56rr	56	1	Among	among	IN
cord-304485-vouu56rr	56	2	others	other	NNS
cord-304485-vouu56rr	56	3	,	,	,
cord-304485-vouu56rr	56	4	I	-PRON-	PRP
cord-304485-vouu56rr	56	5	will	will	MD
cord-304485-vouu56rr	56	6	urge	urge	VB
cord-304485-vouu56rr	56	7	colleagues	colleague	NNS
cord-304485-vouu56rr	56	8	to	to	TO
cord-304485-vouu56rr	56	9	consider	consider	VB
cord-304485-vouu56rr	56	10	essential	essential	JJ
cord-304485-vouu56rr	56	11	a	a	DT
cord-304485-vouu56rr	56	12	comprehensive	comprehensive	JJ
cord-304485-vouu56rr	56	13	immune	immune	JJ
cord-304485-vouu56rr	56	14	profiling	profiling	NN
cord-304485-vouu56rr	56	15	at	at	IN
cord-304485-vouu56rr	56	16	the	the	DT
cord-304485-vouu56rr	56	17	relevant	relevant	JJ
cord-304485-vouu56rr	56	18	mucosae	mucosae	NN
cord-304485-vouu56rr	56	19	coupled	couple	VBN
cord-304485-vouu56rr	56	20	with	with	IN
cord-304485-vouu56rr	56	21	the	the	DT
cord-304485-vouu56rr	56	22	quantification	quantification	NN
cord-304485-vouu56rr	56	23	of	of	IN
cord-304485-vouu56rr	56	24	cytokines	cytokine	NNS
cord-304485-vouu56rr	56	25	and	and	CC
cord-304485-vouu56rr	56	26	chemokines	chemokine	NNS
cord-304485-vouu56rr	56	27	.	.	.
cord-304485-vouu56rr	57	1	Technology	technology	NN
cord-304485-vouu56rr	57	2	such	such	JJ
cord-304485-vouu56rr	57	3	as	as	IN
cord-304485-vouu56rr	57	4	mass	mass	NN
cord-304485-vouu56rr	57	5	cytometry	cytometry	NN
cord-304485-vouu56rr	57	6	could	could	MD
cord-304485-vouu56rr	57	7	improve	improve	VB
cord-304485-vouu56rr	57	8	significantly	significantly	RB
cord-304485-vouu56rr	57	9	the	the	DT
cord-304485-vouu56rr	57	10	breath	breath	NN
cord-304485-vouu56rr	57	11	of	of	IN
cord-304485-vouu56rr	57	12	data	datum	NNS
cord-304485-vouu56rr	57	13	obtained	obtain	VBN
cord-304485-vouu56rr	57	14	while	while	NN
cord-304485-vouu56rr	57	15	,	,	,
cord-304485-vouu56rr	57	16	perhaps	perhaps	RB
cord-304485-vouu56rr	57	17	,	,	,
cord-304485-vouu56rr	57	18	uncovering	uncover	VBG
cord-304485-vouu56rr	57	19	new	new	JJ
cord-304485-vouu56rr	57	20	biology	biology	NN
cord-304485-vouu56rr	57	21	in	in	IN
cord-304485-vouu56rr	57	22	terms	term	NNS
cord-304485-vouu56rr	57	23	of	of	IN
cord-304485-vouu56rr	57	24	immune	immune	JJ
cord-304485-vouu56rr	57	25	populations	population	NNS
cord-304485-vouu56rr	57	26	relevant	relevant	JJ
cord-304485-vouu56rr	57	27	for	for	IN
cord-304485-vouu56rr	57	28	vaccine	vaccine	NN
cord-304485-vouu56rr	57	29	development	development	NN
cord-304485-vouu56rr	57	30	.	.	.
cord-304485-vouu56rr	58	1	After	after	IN
cord-304485-vouu56rr	58	2	developing	develop	VBG
cord-304485-vouu56rr	58	3	AAV	AAV	NNP
cord-304485-vouu56rr	58	4	vectors	vector	NNS
cord-304485-vouu56rr	58	5	expressing	express	VBG
cord-304485-vouu56rr	58	6	influenza	influenza	NN
cord-304485-vouu56rr	58	7	surface	surface	NN
cord-304485-vouu56rr	58	8	exposed	expose	VBN
cord-304485-vouu56rr	58	9	antigens	antigen	NNS
cord-304485-vouu56rr	58	10	,	,	,
cord-304485-vouu56rr	58	11	authors	author	NNS
cord-304485-vouu56rr	58	12	followed	follow	VBD
cord-304485-vouu56rr	58	13	an	an	DT
cord-304485-vouu56rr	58	14	elegant	elegant	JJ
cord-304485-vouu56rr	58	15	pipeline	pipeline	NN
cord-304485-vouu56rr	58	16	probing	probe	VBG
cord-304485-vouu56rr	58	17	their	-PRON-	PRP$
cord-304485-vouu56rr	58	18	vectors	vector	NNS
cord-304485-vouu56rr	58	19	first	first	RB
cord-304485-vouu56rr	58	20	in	in	IN
cord-304485-vouu56rr	58	21	mice	mouse	NNS
cord-304485-vouu56rr	58	22	and	and	CC
cord-304485-vouu56rr	58	23	subsequently	subsequently	RB
cord-304485-vouu56rr	58	24	in	in	IN
cord-304485-vouu56rr	58	25	ferrets	ferret	NNS
cord-304485-vouu56rr	58	26	,	,	,
cord-304485-vouu56rr	58	27	research	research	NN
cord-304485-vouu56rr	58	28	model	model	NN
cord-304485-vouu56rr	58	29	that	that	WDT
cord-304485-vouu56rr	58	30	accurately	accurately	RB
cord-304485-vouu56rr	58	31	recapitulates	recapitulate	VBZ
cord-304485-vouu56rr	58	32	human	human	JJ
cord-304485-vouu56rr	58	33	influenza	influenza	NN
cord-304485-vouu56rr	58	34	infections	infection	NNS
cord-304485-vouu56rr	58	35	.	.	.
cord-304485-vouu56rr	59	1	Vaccines	vaccine	NNS
cord-304485-vouu56rr	59	2	were	be	VBD
cord-304485-vouu56rr	59	3	administered	administer	VBN
cord-304485-vouu56rr	59	4	via	via	IN
cord-304485-vouu56rr	59	5	the	the	DT
cord-304485-vouu56rr	59	6	intranasal	intranasal	NN
cord-304485-vouu56rr	59	7	route	route	NN
cord-304485-vouu56rr	59	8	,	,	,
cord-304485-vouu56rr	59	9	key	key	JJ
cord-304485-vouu56rr	59	10	to	to	TO
cord-304485-vouu56rr	59	11	develop	develop	VB
cord-304485-vouu56rr	59	12	protective	protective	JJ
cord-304485-vouu56rr	59	13	antibodies	antibody	NNS
cord-304485-vouu56rr	59	14	.	.	.
cord-304485-vouu56rr	60	1	Adeno	Adeno	NNP
cord-304485-vouu56rr	60	2	-	-	HYPH
cord-304485-vouu56rr	60	3	associated	associate	VBN
cord-304485-vouu56rr	60	4	virus	virus	NN
cord-304485-vouu56rr	60	5	-	-	HYPH
cord-304485-vouu56rr	60	6	vectored	vectore	VBN
cord-304485-vouu56rr	60	7	influenza	influenza	NN
cord-304485-vouu56rr	60	8	vaccine	vaccine	NN
cord-304485-vouu56rr	60	9	elicits	elicit	VBZ
cord-304485-vouu56rr	61	1	neutralizing	neutralize	VBG
cord-304485-vouu56rr	61	2	and	and	CC
cord-304485-vouu56rr	61	3	Fcgamma	Fcgamma	NNP
cord-304485-vouu56rr	61	4	receptor	receptor	NN
cord-304485-vouu56rr	61	5	-	-	HYPH
cord-304485-vouu56rr	61	6	activating	activate	VBG
cord-304485-vouu56rr	61	7	antibodies	antibody	NNS
cord-304485-vouu56rr	61	8	Broadly	broadly	RB
cord-304485-vouu56rr	61	9	neutralizing	neutralize	VBG
cord-304485-vouu56rr	61	10	anti	anti	JJ
cord-304485-vouu56rr	61	11	-	-	JJ
cord-304485-vouu56rr	61	12	influenza	influenza	JJ
cord-304485-vouu56rr	61	13	antibodies	antibody	NNS
cord-304485-vouu56rr	61	14	require	require	VBP
cord-304485-vouu56rr	61	15	Fc	Fc	NNP
cord-304485-vouu56rr	61	16	receptor	receptor	NN
cord-304485-vouu56rr	61	17	engagement	engagement	NN
cord-304485-vouu56rr	61	18	for	for	IN
cord-304485-vouu56rr	61	19	in	in	IN
cord-304485-vouu56rr	61	20	vivo	vivo	NN
cord-304485-vouu56rr	61	21	protection	protection	NN
cord-304485-vouu56rr	62	1	A	a	DT
cord-304485-vouu56rr	62	2	new	new	JJ
cord-304485-vouu56rr	62	3	genetic	genetic	JJ
cord-304485-vouu56rr	62	4	vaccine	vaccine	NN
cord-304485-vouu56rr	62	5	platform	platform	NN
cord-304485-vouu56rr	62	6	based	base	VBN
cord-304485-vouu56rr	62	7	on	on	IN
cord-304485-vouu56rr	62	8	an	an	DT
cord-304485-vouu56rr	62	9	adeno	adeno	NN
cord-304485-vouu56rr	62	10	-	-	HYPH
cord-304485-vouu56rr	62	11	associated	associate	VBN
cord-304485-vouu56rr	62	12	virus	virus	NN
cord-304485-vouu56rr	62	13	isolated	isolate	VBN
cord-304485-vouu56rr	62	14	from	from	IN
cord-304485-vouu56rr	62	15	a	a	DT
cord-304485-vouu56rr	62	16	rhesus	rhesus	NN
cord-304485-vouu56rr	62	17	macaque	macaque	NN
cord-304485-vouu56rr	62	18	Vaccine	Vaccine	NNP
cord-304485-vouu56rr	62	19	protection	protection	NN
cord-304485-vouu56rr	62	20	against	against	IN
cord-304485-vouu56rr	62	21	lethal	lethal	JJ
cord-304485-vouu56rr	62	22	homologous	homologous	JJ
cord-304485-vouu56rr	62	23	and	and	CC
cord-304485-vouu56rr	62	24	heterologous	heterologous	JJ
cord-304485-vouu56rr	62	25	challenge	challenge	NN
cord-304485-vouu56rr	62	26	using	use	VBG
cord-304485-vouu56rr	62	27	recombinant	recombinant	JJ
cord-304485-vouu56rr	62	28	AAV	AAV	NNP
cord-304485-vouu56rr	62	29	vectors	vector	NNS
cord-304485-vouu56rr	62	30	expressing	express	VBG
cord-304485-vouu56rr	62	31	codon	codon	NN
cord-304485-vouu56rr	62	32	-	-	HYPH
cord-304485-vouu56rr	62	33	optimized	optimize	VBN
cord-304485-vouu56rr	62	34	genes	gene	NNS
cord-304485-vouu56rr	62	35	from	from	IN
cord-304485-vouu56rr	62	36	pandemic	pandemic	NN
cord-304485-vouu56rr	62	37	swine	swine	NNP
cord-304485-vouu56rr	62	38	origin	origin	NNP
cord-304485-vouu56rr	62	39	influenza	influenza	NN
cord-304485-vouu56rr	62	40	virus	virus	NN
cord-304485-vouu56rr	62	41	(	(	-LRB-
cord-304485-vouu56rr	62	42	SOIV	SOIV	NNP
cord-304485-vouu56rr	62	43	)	)	-RRB-
cord-304485-vouu56rr	63	1	A	a	DT
cord-304485-vouu56rr	63	2	perspective	perspective	NN
cord-304485-vouu56rr	63	3	on	on	IN
cord-304485-vouu56rr	63	4	the	the	DT
cord-304485-vouu56rr	63	5	structural	structural	JJ
cord-304485-vouu56rr	63	6	and	and	CC
cord-304485-vouu56rr	63	7	functional	functional	JJ
cord-304485-vouu56rr	63	8	constraints	constraint	NNS
cord-304485-vouu56rr	63	9	for	for	IN
cord-304485-vouu56rr	63	10	immune	immune	JJ
cord-304485-vouu56rr	63	11	evasion	evasion	NN
cord-304485-vouu56rr	63	12	:	:	:
cord-304485-vouu56rr	63	13	insights	insight	NNS
cord-304485-vouu56rr	63	14	from	from	IN
cord-304485-vouu56rr	63	15	influenza	influenza	NN
cord-304485-vouu56rr	63	16	virus	virus	NN
cord-304485-vouu56rr	64	1	A	a	DT
cord-304485-vouu56rr	64	2	novel	novel	NN
cord-304485-vouu56rr	64	3	recombinant	recombinant	JJ
cord-304485-vouu56rr	64	4	adeno	adeno	NN
cord-304485-vouu56rr	64	5	-	-	HYPH
cord-304485-vouu56rr	64	6	associated	associate	VBN
cord-304485-vouu56rr	64	7	virus	virus	NN
cord-304485-vouu56rr	64	8	vaccine	vaccine	NN
cord-304485-vouu56rr	64	9	induces	induce	VBZ
cord-304485-vouu56rr	64	10	a	a	DT
cord-304485-vouu56rr	64	11	longterm	longterm	JJ
cord-304485-vouu56rr	64	12	humoral	humoral	JJ
cord-304485-vouu56rr	64	13	immune	immune	JJ
cord-304485-vouu56rr	64	14	response	response	NN
cord-304485-vouu56rr	64	15	to	to	IN
cord-304485-vouu56rr	64	16	human	human	JJ
cord-304485-vouu56rr	64	17	immunodeficiency	immunodeficiency	NN
cord-304485-vouu56rr	64	18	virus	virus	NN
cord-304485-vouu56rr	64	19	AAV	AAV	NNP
cord-304485-vouu56rr	64	20	vector	vector	NN
cord-304485-vouu56rr	64	21	expressing	express	VBG
cord-304485-vouu56rr	64	22	influenza	influenza	NN
cord-304485-vouu56rr	64	23	surface	surface	NN
cord-304485-vouu56rr	64	24	exposed	expose	VBN
cord-304485-vouu56rr	64	25	antigens	antigen	NNS
cord-304485-vouu56rr	64	26	Testing	testing	NN
cord-304485-vouu56rr	64	27	in	in	IN
cord-304485-vouu56rr	64	28	ferrets	ferret	NNS
cord-304485-vouu56rr	64	29	(	(	-LRB-
cord-304485-vouu56rr	64	30	model	model	NN
cord-304485-vouu56rr	64	31	for	for	IN
cord-304485-vouu56rr	64	32	human	human	JJ
cord-304485-vouu56rr	64	33	influenza	influenza	NN
cord-304485-vouu56rr	64	34	infections	infection	NNS
cord-304485-vouu56rr	64	35	)	)	-RRB-
cord-304485-vouu56rr	64	36	2	2	CD
cord-304485-vouu56rr	64	37	.	.	.