id sid tid token lemma pos cord-327516-i25whxt2 1 1 key key JJ cord-327516-i25whxt2 2 1 : : : cord-327516-i25whxt2 2 2 cord-327516-i25whxt2 cord-327516-i25whxt2 NNP cord-327516-i25whxt2 2 3 authors author NNS cord-327516-i25whxt2 2 4 : : : cord-327516-i25whxt2 2 5 Horby Horby NNP cord-327516-i25whxt2 2 6 , , , cord-327516-i25whxt2 2 7 Peter Peter NNP cord-327516-i25whxt2 2 8 title title NN cord-327516-i25whxt2 2 9 : : : cord-327516-i25whxt2 3 1 Improving improve VBG cord-327516-i25whxt2 3 2 preparedness preparedness NN cord-327516-i25whxt2 3 3 for for IN cord-327516-i25whxt2 3 4 the the DT cord-327516-i25whxt2 3 5 next next JJ cord-327516-i25whxt2 3 6 flu flu NN cord-327516-i25whxt2 3 7 pandemic pandemic NN cord-327516-i25whxt2 3 8 date date NN cord-327516-i25whxt2 3 9 : : : cord-327516-i25whxt2 3 10 2018 2018 CD cord-327516-i25whxt2 3 11 - - HYPH cord-327516-i25whxt2 3 12 07 07 CD cord-327516-i25whxt2 3 13 - - HYPH cord-327516-i25whxt2 3 14 25 25 CD cord-327516-i25whxt2 3 15 journal journal NN cord-327516-i25whxt2 3 16 : : : cord-327516-i25whxt2 4 1 Nat Nat NNP cord-327516-i25whxt2 4 2 Microbiol Microbiol NNP cord-327516-i25whxt2 4 3 DOI DOI NNP cord-327516-i25whxt2 4 4 : : : cord-327516-i25whxt2 4 5 10.1038 10.1038 CD cord-327516-i25whxt2 4 6 / / SYM cord-327516-i25whxt2 4 7 s41564 s41564 NN cord-327516-i25whxt2 4 8 - - HYPH cord-327516-i25whxt2 4 9 018 018 CD cord-327516-i25whxt2 5 1 -0206 -0206 : cord-327516-i25whxt2 5 2 - - : cord-327516-i25whxt2 5 3 7 7 CD cord-327516-i25whxt2 5 4 sha sha NN cord-327516-i25whxt2 5 5 : : : cord-327516-i25whxt2 6 1 e51b87268ab1df469e395d9aaf5262a107030d55 e51b87268ab1df469e395d9aaf5262a107030d55 NNP cord-327516-i25whxt2 6 2 doc_id doc_id CD cord-327516-i25whxt2 6 3 : : : cord-327516-i25whxt2 6 4 327516 327516 CD cord-327516-i25whxt2 6 5 cord_uid cord_uid NNS cord-327516-i25whxt2 6 6 : : : cord-327516-i25whxt2 7 1 i25whxt2 i25whxt2 NNP cord-327516-i25whxt2 8 1 Pandemic pandemic NN cord-327516-i25whxt2 8 2 influenza influenza NN cord-327516-i25whxt2 8 3 remains remain VBZ cord-327516-i25whxt2 8 4 the the DT cord-327516-i25whxt2 8 5 single single JJ cord-327516-i25whxt2 8 6 greatest great JJS cord-327516-i25whxt2 8 7 threat threat NN cord-327516-i25whxt2 8 8 to to IN cord-327516-i25whxt2 8 9 global global JJ cord-327516-i25whxt2 8 10 heath heath NNP cord-327516-i25whxt2 8 11 security security NN cord-327516-i25whxt2 8 12 . . . cord-327516-i25whxt2 9 1 Efforts effort NNS cord-327516-i25whxt2 9 2 to to TO cord-327516-i25whxt2 9 3 increase increase VB cord-327516-i25whxt2 9 4 our -PRON- PRP$ cord-327516-i25whxt2 9 5 preparedness preparedness NN cord-327516-i25whxt2 9 6 , , , cord-327516-i25whxt2 9 7 by by IN cord-327516-i25whxt2 9 8 improving improve VBG cord-327516-i25whxt2 9 9 predictions prediction NNS cord-327516-i25whxt2 9 10 of of IN cord-327516-i25whxt2 9 11 viral viral JJ cord-327516-i25whxt2 9 12 emergence emergence NN cord-327516-i25whxt2 9 13 , , , cord-327516-i25whxt2 9 14 spread spread NN cord-327516-i25whxt2 9 15 and and CC cord-327516-i25whxt2 9 16 disease disease NN cord-327516-i25whxt2 9 17 severity severity NN cord-327516-i25whxt2 9 18 , , , cord-327516-i25whxt2 9 19 by by IN cord-327516-i25whxt2 9 20 targeting target VBG cord-327516-i25whxt2 9 21 reduced reduced JJ cord-327516-i25whxt2 9 22 transmission transmission NN cord-327516-i25whxt2 9 23 and and CC cord-327516-i25whxt2 9 24 improved improved JJ cord-327516-i25whxt2 9 25 vaccination vaccination NN cord-327516-i25whxt2 9 26 and and CC cord-327516-i25whxt2 9 27 by by IN cord-327516-i25whxt2 9 28 mitigating mitigate VBG cord-327516-i25whxt2 9 29 health health NN cord-327516-i25whxt2 9 30 impacts impact NNS cord-327516-i25whxt2 9 31 in in IN cord-327516-i25whxt2 9 32 low- low- NN cord-327516-i25whxt2 9 33 and and CC cord-327516-i25whxt2 9 34 middle middle JJ cord-327516-i25whxt2 9 35 - - HYPH cord-327516-i25whxt2 9 36 income income NN cord-327516-i25whxt2 9 37 countries country NNS cord-327516-i25whxt2 9 38 , , , cord-327516-i25whxt2 9 39 should should MD cord-327516-i25whxt2 9 40 receive receive VB cord-327516-i25whxt2 9 41 renewed renew VBN cord-327516-i25whxt2 9 42 urgency urgency NN cord-327516-i25whxt2 9 43 . . . cord-327516-i25whxt2 10 1 G G NNP cord-327516-i25whxt2 10 2 iven iven VBD cord-327516-i25whxt2 10 3 its -PRON- PRP$ cord-327516-i25whxt2 10 4 potential potential NN cord-327516-i25whxt2 10 5 to to TO cord-327516-i25whxt2 10 6 cause cause VB cord-327516-i25whxt2 10 7 an an DT cord-327516-i25whxt2 10 8 acute acute JJ cord-327516-i25whxt2 10 9 global global JJ cord-327516-i25whxt2 10 10 health health NN cord-327516-i25whxt2 10 11 crisis crisis NN cord-327516-i25whxt2 10 12 with with IN cord-327516-i25whxt2 10 13 many many JJ cord-327516-i25whxt2 10 14 millions million NNS cord-327516-i25whxt2 10 15 of of IN cord-327516-i25whxt2 10 16 deaths death NNS cord-327516-i25whxt2 10 17 , , , cord-327516-i25whxt2 10 18 pandemic pandemic NN cord-327516-i25whxt2 10 19 influenza influenza NN cord-327516-i25whxt2 10 20 can can MD cord-327516-i25whxt2 10 21 rightly rightly RB cord-327516-i25whxt2 10 22 be be VB cord-327516-i25whxt2 10 23 considered consider VBN cord-327516-i25whxt2 10 24 the the DT cord-327516-i25whxt2 10 25 greatest great JJS cord-327516-i25whxt2 10 26 single single JJ cord-327516-i25whxt2 10 27 threat threat NN cord-327516-i25whxt2 10 28 to to IN cord-327516-i25whxt2 10 29 global global JJ cord-327516-i25whxt2 10 30 health health NN cord-327516-i25whxt2 10 31 security security NN cord-327516-i25whxt2 10 32 . . . cord-327516-i25whxt2 11 1 Yet yet CC cord-327516-i25whxt2 11 2 despite despite IN cord-327516-i25whxt2 11 3 this this DT cord-327516-i25whxt2 11 4 threat threat NN cord-327516-i25whxt2 11 5 , , , cord-327516-i25whxt2 11 6 influenza influenza NN cord-327516-i25whxt2 11 7 has have VBZ cord-327516-i25whxt2 11 8 recently recently RB cord-327516-i25whxt2 11 9 been be VBN cord-327516-i25whxt2 11 10 eclipsed eclipse VBN cord-327516-i25whxt2 11 11 in in IN cord-327516-i25whxt2 11 12 the the DT cord-327516-i25whxt2 11 13 popular popular JJ cord-327516-i25whxt2 11 14 and and CC cord-327516-i25whxt2 11 15 scientific scientific JJ cord-327516-i25whxt2 11 16 consciousness consciousness NN cord-327516-i25whxt2 11 17 by by IN cord-327516-i25whxt2 11 18 less less JJR cord-327516-i25whxt2 11 19 common common JJ cord-327516-i25whxt2 11 20 infections infection NNS cord-327516-i25whxt2 11 21 , , , cord-327516-i25whxt2 11 22 such such JJ cord-327516-i25whxt2 11 23 as as IN cord-327516-i25whxt2 11 24 those those DT cord-327516-i25whxt2 11 25 caused cause VBN cord-327516-i25whxt2 11 26 by by IN cord-327516-i25whxt2 11 27 Ebola Ebola NNP cord-327516-i25whxt2 11 28 and and CC cord-327516-i25whxt2 11 29 Zika Zika NNP cord-327516-i25whxt2 11 30 viruses virus NNS cord-327516-i25whxt2 11 31 . . . cord-327516-i25whxt2 12 1 The the DT cord-327516-i25whxt2 12 2 centenary centenary NN cord-327516-i25whxt2 12 3 of of IN cord-327516-i25whxt2 12 4 the the DT cord-327516-i25whxt2 12 5 1918 1918 CD cord-327516-i25whxt2 12 6 influenza influenza NN cord-327516-i25whxt2 12 7 pandemic pandemic NN cord-327516-i25whxt2 12 8 , , , cord-327516-i25whxt2 12 9 which which WDT cord-327516-i25whxt2 12 10 is be VBZ cord-327516-i25whxt2 12 11 estimated estimate VBN cord-327516-i25whxt2 12 12 to to TO cord-327516-i25whxt2 12 13 have have VB cord-327516-i25whxt2 12 14 killed kill VBN cord-327516-i25whxt2 12 15 50 50 CD cord-327516-i25whxt2 12 16 million million CD cord-327516-i25whxt2 12 17 people people NNS cord-327516-i25whxt2 12 18 , , , cord-327516-i25whxt2 12 19 is be VBZ cord-327516-i25whxt2 12 20 an an DT cord-327516-i25whxt2 12 21 opportune opportune JJ cord-327516-i25whxt2 12 22 time time NN cord-327516-i25whxt2 12 23 to to TO cord-327516-i25whxt2 12 24 remind remind VB cord-327516-i25whxt2 12 25 ourselves -PRON- PRP cord-327516-i25whxt2 12 26 that that IN cord-327516-i25whxt2 12 27 the the DT cord-327516-i25whxt2 12 28 greatest great JJS cord-327516-i25whxt2 12 29 risks risk NNS cord-327516-i25whxt2 12 30 often often RB cord-327516-i25whxt2 12 31 lay lie VBD cord-327516-i25whxt2 12 32 in in IN cord-327516-i25whxt2 12 33 the the DT cord-327516-i25whxt2 12 34 mundane mundane JJ cord-327516-i25whxt2 12 35 . . . cord-327516-i25whxt2 13 1 Much much RB cord-327516-i25whxt2 13 2 like like IN cord-327516-i25whxt2 13 3 we -PRON- PRP cord-327516-i25whxt2 13 4 need need VBP cord-327516-i25whxt2 13 5 reminding remind VBG cord-327516-i25whxt2 13 6 that that IN cord-327516-i25whxt2 13 7 driving driving NN cord-327516-i25whxt2 13 8 is be VBZ cord-327516-i25whxt2 13 9 far far RB cord-327516-i25whxt2 13 10 more more RBR cord-327516-i25whxt2 13 11 dangerous dangerous JJ cord-327516-i25whxt2 13 12 than than IN cord-327516-i25whxt2 13 13 flying fly VBG cord-327516-i25whxt2 13 14 , , , cord-327516-i25whxt2 13 15 familiarity familiarity NN cord-327516-i25whxt2 13 16 can can MD cord-327516-i25whxt2 13 17 breed breed VB cord-327516-i25whxt2 13 18 contempt contempt NN cord-327516-i25whxt2 13 19 . . . cord-327516-i25whxt2 14 1 The the DT cord-327516-i25whxt2 14 2 appearance appearance NN cord-327516-i25whxt2 14 3 of of IN cord-327516-i25whxt2 14 4 a a DT cord-327516-i25whxt2 14 5 human human JJ cord-327516-i25whxt2 14 6 influenza influenza NN cord-327516-i25whxt2 14 7 pandemic pandemic NN cord-327516-i25whxt2 14 8 depends depend VBZ cord-327516-i25whxt2 14 9 on on IN cord-327516-i25whxt2 14 10 the the DT cord-327516-i25whxt2 14 11 emergence emergence NN cord-327516-i25whxt2 14 12 of of IN cord-327516-i25whxt2 14 13 a a DT cord-327516-i25whxt2 14 14 novel novel JJ cord-327516-i25whxt2 14 15 virus virus NN cord-327516-i25whxt2 14 16 that that WDT cord-327516-i25whxt2 14 17 can can MD cord-327516-i25whxt2 14 18 readily readily RB cord-327516-i25whxt2 14 19 infect infect VB cord-327516-i25whxt2 14 20 and and CC cord-327516-i25whxt2 14 21 transmit transmit VB cord-327516-i25whxt2 14 22 between between IN cord-327516-i25whxt2 14 23 people people NNS cord-327516-i25whxt2 14 24 . . . cord-327516-i25whxt2 15 1 The the DT cord-327516-i25whxt2 15 2 mostly mostly RB cord-327516-i25whxt2 15 3 likely likely JJ cord-327516-i25whxt2 15 4 source source NN cord-327516-i25whxt2 15 5 of of IN cord-327516-i25whxt2 15 6 a a DT cord-327516-i25whxt2 15 7 pandemic pandemic NN cord-327516-i25whxt2 15 8 virus virus NN cord-327516-i25whxt2 15 9 is be VBZ cord-327516-i25whxt2 15 10 the the DT cord-327516-i25whxt2 15 11 pool pool NN cord-327516-i25whxt2 15 12 of of IN cord-327516-i25whxt2 15 13 influenza influenza NN cord-327516-i25whxt2 15 14 viruses virus NNS cord-327516-i25whxt2 15 15 that that WDT cord-327516-i25whxt2 15 16 infect infect VBP cord-327516-i25whxt2 15 17 animals animal NNS cord-327516-i25whxt2 15 18 such such JJ cord-327516-i25whxt2 15 19 as as IN cord-327516-i25whxt2 15 20 wild wild JJ cord-327516-i25whxt2 15 21 birds bird NNS cord-327516-i25whxt2 15 22 ( ( -LRB- cord-327516-i25whxt2 15 23 the the DT cord-327516-i25whxt2 15 24 natural natural JJ cord-327516-i25whxt2 15 25 reservoir reservoir NN cord-327516-i25whxt2 15 26 of of IN cord-327516-i25whxt2 15 27 influenza influenza NN cord-327516-i25whxt2 15 28 A a DT cord-327516-i25whxt2 15 29 viruses virus NNS cord-327516-i25whxt2 15 30 ) ) -RRB- cord-327516-i25whxt2 15 31 , , , cord-327516-i25whxt2 15 32 domestic domestic JJ cord-327516-i25whxt2 15 33 poultry poultry NN cord-327516-i25whxt2 15 34 and and CC cord-327516-i25whxt2 15 35 pigs pig NNS cord-327516-i25whxt2 15 36 . . . cord-327516-i25whxt2 16 1 The the DT cord-327516-i25whxt2 16 2 scale scale NN cord-327516-i25whxt2 16 3 of of IN cord-327516-i25whxt2 16 4 pig pig NN cord-327516-i25whxt2 16 5 and and CC cord-327516-i25whxt2 16 6 poultry poultry NN cord-327516-i25whxt2 16 7 farming farming NN cord-327516-i25whxt2 16 8 has have VBZ cord-327516-i25whxt2 16 9 increased increase VBN cord-327516-i25whxt2 16 10 massively massively RB cord-327516-i25whxt2 16 11 over over IN cord-327516-i25whxt2 16 12 the the DT cord-327516-i25whxt2 16 13 past past JJ cord-327516-i25whxt2 16 14 50 50 CD cord-327516-i25whxt2 16 15 years year NNS cord-327516-i25whxt2 16 16 , , , cord-327516-i25whxt2 16 17 with with IN cord-327516-i25whxt2 16 18 the the DT cord-327516-i25whxt2 16 19 estimated estimate VBN cord-327516-i25whxt2 16 20 global global JJ cord-327516-i25whxt2 16 21 number number NN cord-327516-i25whxt2 16 22 of of IN cord-327516-i25whxt2 16 23 pigs pig NNS cord-327516-i25whxt2 16 24 and and CC cord-327516-i25whxt2 16 25 chickens chicken NNS cord-327516-i25whxt2 16 26 having have VBG cord-327516-i25whxt2 16 27 increased increase VBN cord-327516-i25whxt2 16 28 roughly roughly RB cord-327516-i25whxt2 16 29 twofold twofold JJ cord-327516-i25whxt2 16 30 and and CC cord-327516-i25whxt2 16 31 fivefold fivefold JJ cord-327516-i25whxt2 16 32 , , , cord-327516-i25whxt2 16 33 respectively respectively RB cord-327516-i25whxt2 16 34 , , , cord-327516-i25whxt2 16 35 from from IN cord-327516-i25whxt2 16 36 the the DT cord-327516-i25whxt2 16 37 early early JJ cord-327516-i25whxt2 16 38 1960s 1960 NNS cord-327516-i25whxt2 16 39 until until IN cord-327516-i25whxt2 16 40 now now RB cord-327516-i25whxt2 16 41 ( ( -LRB- cord-327516-i25whxt2 16 42 from from IN cord-327516-i25whxt2 16 43 400 400 CD cord-327516-i25whxt2 16 44 million million CD cord-327516-i25whxt2 16 45 to to TO cord-327516-i25whxt2 16 46 around around IN cord-327516-i25whxt2 16 47 1 1 CD cord-327516-i25whxt2 16 48 billion billion CD cord-327516-i25whxt2 16 49 pigs pig NNS cord-327516-i25whxt2 16 50 ; ; : cord-327516-i25whxt2 16 51 and and CC cord-327516-i25whxt2 16 52 4 4 CD cord-327516-i25whxt2 16 53 billion billion CD cord-327516-i25whxt2 16 54 to to TO cord-327516-i25whxt2 16 55 20 20 CD cord-327516-i25whxt2 16 56 billion billion CD cord-327516-i25whxt2 16 57 chickens chicken NNS cord-327516-i25whxt2 16 58 ) ) -RRB- cord-327516-i25whxt2 16 59 1 1 CD cord-327516-i25whxt2 16 60 . . . cord-327516-i25whxt2 17 1 Swine swine NN cord-327516-i25whxt2 17 2 influenza influenza NN cord-327516-i25whxt2 17 3 is be VBZ cord-327516-i25whxt2 17 4 endemic endemic JJ cord-327516-i25whxt2 17 5 in in IN cord-327516-i25whxt2 17 6 pig pig NN cord-327516-i25whxt2 17 7 populations population NNS cord-327516-i25whxt2 17 8 , , , cord-327516-i25whxt2 17 9 with with IN cord-327516-i25whxt2 17 10 co co NN cord-327516-i25whxt2 17 11 - - NN cord-327516-i25whxt2 17 12 circulation circulation NN cord-327516-i25whxt2 17 13 of of IN cord-327516-i25whxt2 17 14 multiple multiple JJ cord-327516-i25whxt2 17 15 subtypes subtype NNS cord-327516-i25whxt2 17 16 and and CC cord-327516-i25whxt2 17 17 the the DT cord-327516-i25whxt2 17 18 intermittent intermittent JJ cord-327516-i25whxt2 17 19 introduction introduction NN cord-327516-i25whxt2 17 20 of of IN cord-327516-i25whxt2 17 21 new new JJ cord-327516-i25whxt2 17 22 strains strain NNS cord-327516-i25whxt2 17 23 from from IN cord-327516-i25whxt2 17 24 avian avian JJ cord-327516-i25whxt2 17 25 or or CC cord-327516-i25whxt2 17 26 human human JJ cord-327516-i25whxt2 17 27 sources source NNS cord-327516-i25whxt2 17 28 , , , cord-327516-i25whxt2 17 29 whilst whilst IN cord-327516-i25whxt2 17 30 poultry poultry NN cord-327516-i25whxt2 17 31 populations population NNS cord-327516-i25whxt2 17 32 are be VBP cord-327516-i25whxt2 17 33 affected affect VBN cord-327516-i25whxt2 17 34 by by IN cord-327516-i25whxt2 17 35 an an DT cord-327516-i25whxt2 17 36 increasing increase VBG cord-327516-i25whxt2 17 37 variety variety NN cord-327516-i25whxt2 17 38 of of IN cord-327516-i25whxt2 17 39 influenza influenza NN cord-327516-i25whxt2 17 40 viruses virus NNS cord-327516-i25whxt2 17 41 . . . cord-327516-i25whxt2 18 1 Human human JJ cord-327516-i25whxt2 18 2 infections infection NNS cord-327516-i25whxt2 18 3 with with IN cord-327516-i25whxt2 18 4 a a DT cord-327516-i25whxt2 18 5 diverse diverse JJ cord-327516-i25whxt2 18 6 range range NN cord-327516-i25whxt2 18 7 of of IN cord-327516-i25whxt2 18 8 zoonotic zoonotic JJ cord-327516-i25whxt2 18 9 influenza influenza NN cord-327516-i25whxt2 18 10 viruses virus NNS cord-327516-i25whxt2 18 11 are be VBP cord-327516-i25whxt2 18 12 now now RB cord-327516-i25whxt2 18 13 being be VBG cord-327516-i25whxt2 18 14 detected detect VBN cord-327516-i25whxt2 18 15 ( ( -LRB- cord-327516-i25whxt2 18 16 Fig fig NN cord-327516-i25whxt2 18 17 . . . cord-327516-i25whxt2 18 18 1 1 CD cord-327516-i25whxt2 18 19 ) ) -RRB- cord-327516-i25whxt2 18 20 , , , cord-327516-i25whxt2 18 21 some some DT cord-327516-i25whxt2 18 22 of of IN cord-327516-i25whxt2 18 23 which which WDT cord-327516-i25whxt2 18 24 are be VBP cord-327516-i25whxt2 18 25 associated associate VBN cord-327516-i25whxt2 18 26 with with IN cord-327516-i25whxt2 18 27 a a DT cord-327516-i25whxt2 18 28 high high JJ cord-327516-i25whxt2 18 29 case case NN cord-327516-i25whxt2 18 30 fatality fatality NN cord-327516-i25whxt2 18 31 rate rate NN cord-327516-i25whxt2 18 32 , , , cord-327516-i25whxt2 18 33 and and CC cord-327516-i25whxt2 18 34 some some DT cord-327516-i25whxt2 18 35 of of IN cord-327516-i25whxt2 18 36 which which WDT cord-327516-i25whxt2 18 37 have have VBP cord-327516-i25whxt2 18 38 mutations mutation NNS cord-327516-i25whxt2 18 39 that that WDT cord-327516-i25whxt2 18 40 confer confer VBP cord-327516-i25whxt2 18 41 resistance resistance NN cord-327516-i25whxt2 18 42 to to IN cord-327516-i25whxt2 18 43 the the DT cord-327516-i25whxt2 18 44 major major JJ cord-327516-i25whxt2 18 45 classes class NNS cord-327516-i25whxt2 18 46 of of IN cord-327516-i25whxt2 18 47 influenza influenza NN cord-327516-i25whxt2 18 48 antiviral antiviral JJ cord-327516-i25whxt2 18 49 drugs drug NNS cord-327516-i25whxt2 18 50 . . . cord-327516-i25whxt2 19 1 Although although IN cord-327516-i25whxt2 19 2 it -PRON- PRP cord-327516-i25whxt2 19 3 is be VBZ cord-327516-i25whxt2 19 4 hard hard JJ cord-327516-i25whxt2 19 5 to to TO cord-327516-i25whxt2 19 6 be be VB cord-327516-i25whxt2 19 7 sure sure JJ cord-327516-i25whxt2 19 8 as as IN cord-327516-i25whxt2 19 9 surveillance surveillance NN cord-327516-i25whxt2 19 10 and and CC cord-327516-i25whxt2 19 11 genetic genetic JJ cord-327516-i25whxt2 19 12 sequencing sequencing NN cord-327516-i25whxt2 19 13 capabilities capability NNS cord-327516-i25whxt2 19 14 have have VBP cord-327516-i25whxt2 19 15 been be VBN cord-327516-i25whxt2 19 16 increasing increase VBG cord-327516-i25whxt2 19 17 , , , cord-327516-i25whxt2 19 18 we -PRON- PRP cord-327516-i25whxt2 19 19 seem seem VBP cord-327516-i25whxt2 19 20 to to TO cord-327516-i25whxt2 19 21 be be VB cord-327516-i25whxt2 19 22 experiencing experience VBG cord-327516-i25whxt2 19 23 a a DT cord-327516-i25whxt2 19 24 notable notable JJ cord-327516-i25whxt2 19 25 increase increase NN cord-327516-i25whxt2 19 26 in in IN cord-327516-i25whxt2 19 27 the the DT cord-327516-i25whxt2 19 28 genetic genetic JJ cord-327516-i25whxt2 19 29 exchange exchange NN cord-327516-i25whxt2 19 30 and and CC cord-327516-i25whxt2 19 31 diversification diversification NN cord-327516-i25whxt2 19 32 of of IN cord-327516-i25whxt2 19 33 animal animal NN cord-327516-i25whxt2 19 34 influenza influenza NN cord-327516-i25whxt2 19 35 viruses virus NNS cord-327516-i25whxt2 19 36 2 2 CD cord-327516-i25whxt2 19 37 . . . cord-327516-i25whxt2 20 1 Determining determine VBG cord-327516-i25whxt2 20 2 which which WDT cord-327516-i25whxt2 20 3 of of IN cord-327516-i25whxt2 20 4 these these DT cord-327516-i25whxt2 20 5 viruses virus NNS cord-327516-i25whxt2 20 6 will will MD cord-327516-i25whxt2 20 7 cause cause VB cord-327516-i25whxt2 20 8 the the DT cord-327516-i25whxt2 20 9 next next JJ cord-327516-i25whxt2 20 10 pandemic pandemic NN cord-327516-i25whxt2 20 11 , , , cord-327516-i25whxt2 20 12 when when WRB cord-327516-i25whxt2 20 13 it -PRON- PRP cord-327516-i25whxt2 20 14 will will MD cord-327516-i25whxt2 20 15 happen happen VB cord-327516-i25whxt2 20 16 and and CC cord-327516-i25whxt2 20 17 how how WRB cord-327516-i25whxt2 20 18 bad bad JJ cord-327516-i25whxt2 20 19 it -PRON- PRP cord-327516-i25whxt2 20 20 will will MD cord-327516-i25whxt2 20 21 be be VB cord-327516-i25whxt2 20 22 remains remain VBZ cord-327516-i25whxt2 20 23 incredibly incredibly RB cord-327516-i25whxt2 20 24 challenging challenging JJ cord-327516-i25whxt2 20 25 . . . cord-327516-i25whxt2 21 1 However however RB cord-327516-i25whxt2 21 2 , , , cord-327516-i25whxt2 21 3 there there EX cord-327516-i25whxt2 21 4 are be VBP cord-327516-i25whxt2 21 5 warning warn VBG cord-327516-i25whxt2 21 6 signs sign NNS cord-327516-i25whxt2 21 7 to to TO cord-327516-i25whxt2 21 8 be be VB cord-327516-i25whxt2 21 9 heeded heed VBN cord-327516-i25whxt2 21 10 and and CC cord-327516-i25whxt2 21 11 areas area NNS cord-327516-i25whxt2 21 12 in in IN cord-327516-i25whxt2 21 13 which which WDT cord-327516-i25whxt2 21 14 our -PRON- PRP$ cord-327516-i25whxt2 21 15 preparedness preparedness NN cord-327516-i25whxt2 21 16 could could MD cord-327516-i25whxt2 21 17 be be VB cord-327516-i25whxt2 21 18 strengthened strengthen VBN cord-327516-i25whxt2 21 19 to to TO cord-327516-i25whxt2 21 20 make make VB cord-327516-i25whxt2 21 21 sure sure JJ cord-327516-i25whxt2 21 22 that that IN cord-327516-i25whxt2 21 23 we -PRON- PRP cord-327516-i25whxt2 21 24 are be VBP cord-327516-i25whxt2 21 25 best well RBS cord-327516-i25whxt2 21 26 placed place VBN cord-327516-i25whxt2 21 27 to to TO cord-327516-i25whxt2 21 28 identify identify VB cord-327516-i25whxt2 21 29 and and CC cord-327516-i25whxt2 21 30 swiftly swiftly RB cord-327516-i25whxt2 21 31 confront confront VB cord-327516-i25whxt2 21 32 the the DT cord-327516-i25whxt2 21 33 next next JJ cord-327516-i25whxt2 21 34 influenza influenza NN cord-327516-i25whxt2 21 35 pandemic pandemic NN cord-327516-i25whxt2 21 36 . . . cord-327516-i25whxt2 22 1 Influenza influenza NN cord-327516-i25whxt2 22 2 is be VBZ cord-327516-i25whxt2 22 3 probably probably RB cord-327516-i25whxt2 22 4 one one CD cord-327516-i25whxt2 22 5 of of IN cord-327516-i25whxt2 22 6 the the DT cord-327516-i25whxt2 22 7 most most RBS cord-327516-i25whxt2 22 8 studied study VBN cord-327516-i25whxt2 22 9 viruses virus NNS cord-327516-i25whxt2 22 10 , , , cord-327516-i25whxt2 22 11 yet yet CC cord-327516-i25whxt2 22 12 fundamental fundamental JJ cord-327516-i25whxt2 22 13 gaps gap NNS cord-327516-i25whxt2 22 14 exist exist VBP cord-327516-i25whxt2 22 15 in in IN cord-327516-i25whxt2 22 16 our -PRON- PRP$ cord-327516-i25whxt2 22 17 ability ability NN cord-327516-i25whxt2 22 18 to to TO cord-327516-i25whxt2 22 19 predict predict VB cord-327516-i25whxt2 22 20 the the DT cord-327516-i25whxt2 22 21 transmissibility transmissibility NN cord-327516-i25whxt2 22 22 and and CC cord-327516-i25whxt2 22 23 virulence virulence NN cord-327516-i25whxt2 22 24 of of IN cord-327516-i25whxt2 22 25 novel novel NN cord-327516-i25whxt2 22 26 influenza influenza NN cord-327516-i25whxt2 22 27 viruses virus NNS cord-327516-i25whxt2 22 28 . . . cord-327516-i25whxt2 23 1 The the DT cord-327516-i25whxt2 23 2 recent recent JJ cord-327516-i25whxt2 23 3 lifting lifting NN cord-327516-i25whxt2 23 4 by by IN cord-327516-i25whxt2 23 5 the the DT cord-327516-i25whxt2 23 6 US US NNP cord-327516-i25whxt2 23 7 National National NNP cord-327516-i25whxt2 23 8 Institutes Institutes NNPS cord-327516-i25whxt2 23 9 of of IN cord-327516-i25whxt2 23 10 Health Health NNP cord-327516-i25whxt2 23 11 of of IN cord-327516-i25whxt2 23 12 their -PRON- PRP$ cord-327516-i25whxt2 23 13 moratorium moratorium NN cord-327516-i25whxt2 23 14 3 3 CD cord-327516-i25whxt2 23 15 on on IN cord-327516-i25whxt2 23 16 funding funding NN cord-327516-i25whxt2 23 17 of of IN cord-327516-i25whxt2 23 18 so so RB cord-327516-i25whxt2 23 19 - - HYPH cord-327516-i25whxt2 23 20 called call VBN cord-327516-i25whxt2 23 21 ' ' `` cord-327516-i25whxt2 23 22 gain gain NN cord-327516-i25whxt2 23 23 - - HYPH cord-327516-i25whxt2 23 24 of of IN cord-327516-i25whxt2 23 25 - - HYPH cord-327516-i25whxt2 23 26 function function NN cord-327516-i25whxt2 23 27 ' ' '' cord-327516-i25whxt2 23 28 experiments experiment NNS cord-327516-i25whxt2 23 29 ( ( -LRB- cord-327516-i25whxt2 23 30 laboratory laboratory NN cord-327516-i25whxt2 23 31 experiments experiment NNS cord-327516-i25whxt2 23 32 where where WRB cord-327516-i25whxt2 23 33 viruses virus NNS cord-327516-i25whxt2 23 34 are be VBP cord-327516-i25whxt2 23 35 genetically genetically RB cord-327516-i25whxt2 23 36 altered alter VBN cord-327516-i25whxt2 23 37 to to TO cord-327516-i25whxt2 23 38 assess assess VB cord-327516-i25whxt2 23 39 the the DT cord-327516-i25whxt2 23 40 effect effect NN cord-327516-i25whxt2 23 41 on on IN cord-327516-i25whxt2 23 42 properties property NNS cord-327516-i25whxt2 23 43 such such JJ cord-327516-i25whxt2 23 44 as as IN cord-327516-i25whxt2 23 45 transmissibility transmissibility NN cord-327516-i25whxt2 23 46 and and CC cord-327516-i25whxt2 23 47 virulence virulence NN cord-327516-i25whxt2 23 48 ) ) -RRB- cord-327516-i25whxt2 23 49 is be VBZ cord-327516-i25whxt2 23 50 good good JJ cord-327516-i25whxt2 23 51 news news NN cord-327516-i25whxt2 23 52 , , , cord-327516-i25whxt2 23 53 as as IN cord-327516-i25whxt2 23 54 it -PRON- PRP cord-327516-i25whxt2 23 55 allows allow VBZ cord-327516-i25whxt2 23 56 us -PRON- PRP cord-327516-i25whxt2 23 57 to to TO cord-327516-i25whxt2 23 58 explore explore VB cord-327516-i25whxt2 23 59 the the DT cord-327516-i25whxt2 23 60 limits limit NNS cord-327516-i25whxt2 23 61 of of IN cord-327516-i25whxt2 23 62 evolution evolution NN cord-327516-i25whxt2 23 63 and and CC cord-327516-i25whxt2 23 64 the the DT cord-327516-i25whxt2 23 65 genotypic genotypic JJ cord-327516-i25whxt2 23 66 predictors predictor NNS cord-327516-i25whxt2 23 67 of of IN cord-327516-i25whxt2 23 68 phenotype phenotype NN cord-327516-i25whxt2 23 69 4 4 CD cord-327516-i25whxt2 23 70 . . . cord-327516-i25whxt2 24 1 However however RB cord-327516-i25whxt2 24 2 , , , cord-327516-i25whxt2 24 3 there there EX cord-327516-i25whxt2 24 4 are be VBP cord-327516-i25whxt2 24 5 limits limit NNS cord-327516-i25whxt2 24 6 to to IN cord-327516-i25whxt2 24 7 the the DT cord-327516-i25whxt2 24 8 predictive predictive JJ cord-327516-i25whxt2 24 9 value value NN cord-327516-i25whxt2 24 10 of of IN cord-327516-i25whxt2 24 11 laboratory laboratory NN cord-327516-i25whxt2 24 12 experiments experiment NNS cord-327516-i25whxt2 24 13 and and CC cord-327516-i25whxt2 24 14 animal animal NN cord-327516-i25whxt2 24 15 models model NNS cord-327516-i25whxt2 24 16 , , , cord-327516-i25whxt2 24 17 and and CC cord-327516-i25whxt2 24 18 when when WRB cord-327516-i25whxt2 24 19 a a DT cord-327516-i25whxt2 24 20 new new JJ cord-327516-i25whxt2 24 21 pandemic pandemic NN cord-327516-i25whxt2 24 22 virus virus NN cord-327516-i25whxt2 24 23 does do VBZ cord-327516-i25whxt2 24 24 emerge emerge VB cord-327516-i25whxt2 24 25 , , , cord-327516-i25whxt2 24 26 which which WDT cord-327516-i25whxt2 24 27 inevitably inevitably RB cord-327516-i25whxt2 24 28 it -PRON- PRP cord-327516-i25whxt2 24 29 will will MD cord-327516-i25whxt2 24 30 , , , cord-327516-i25whxt2 24 31 the the DT cord-327516-i25whxt2 24 32 most most RBS cord-327516-i25whxt2 24 33 important important JJ cord-327516-i25whxt2 24 34 measure measure NN cord-327516-i25whxt2 24 35 will will MD cord-327516-i25whxt2 24 36 be be VB cord-327516-i25whxt2 24 37 the the DT cord-327516-i25whxt2 24 38 disease disease NN cord-327516-i25whxt2 24 39 severity severity NN cord-327516-i25whxt2 24 40 per per IN cord-327516-i25whxt2 24 41 infected infected JJ cord-327516-i25whxt2 24 42 person person NN cord-327516-i25whxt2 24 43 . . . cord-327516-i25whxt2 25 1 This this DT cord-327516-i25whxt2 25 2 information information NN cord-327516-i25whxt2 25 3 is be VBZ cord-327516-i25whxt2 25 4 crucial crucial JJ cord-327516-i25whxt2 25 5 for for IN cord-327516-i25whxt2 25 6 understanding understand VBG cord-327516-i25whxt2 25 7 the the DT cord-327516-i25whxt2 25 8 potential potential JJ cord-327516-i25whxt2 25 9 impact impact NN cord-327516-i25whxt2 25 10 of of IN cord-327516-i25whxt2 25 11 the the DT cord-327516-i25whxt2 25 12 pandemic pandemic NN cord-327516-i25whxt2 25 13 and and CC cord-327516-i25whxt2 25 14 appropriately appropriately RB cord-327516-i25whxt2 25 15 calibrating calibrate VBG cord-327516-i25whxt2 25 16 the the DT cord-327516-i25whxt2 25 17 political political JJ cord-327516-i25whxt2 25 18 and and CC cord-327516-i25whxt2 25 19 public public JJ cord-327516-i25whxt2 25 20 health health NN cord-327516-i25whxt2 25 21 response response NN cord-327516-i25whxt2 25 22 . . . cord-327516-i25whxt2 26 1 Estimating estimate VBG cord-327516-i25whxt2 26 2 the the DT cord-327516-i25whxt2 26 3 severity severity NN cord-327516-i25whxt2 26 4 per per IN cord-327516-i25whxt2 26 5 infected infected JJ cord-327516-i25whxt2 26 6 person person NN cord-327516-i25whxt2 26 7 requires require VBZ cord-327516-i25whxt2 26 8 robust robust JJ cord-327516-i25whxt2 26 9 and and CC cord-327516-i25whxt2 26 10 real real JJ cord-327516-i25whxt2 26 11 - - HYPH cord-327516-i25whxt2 26 12 time time NN cord-327516-i25whxt2 26 13 data datum NNS cord-327516-i25whxt2 26 14 on on IN cord-327516-i25whxt2 26 15 the the DT cord-327516-i25whxt2 26 16 number number NN cord-327516-i25whxt2 26 17 of of IN cord-327516-i25whxt2 26 18 people people NNS cord-327516-i25whxt2 26 19 infected infect VBN cord-327516-i25whxt2 26 20 and and CC cord-327516-i25whxt2 26 21 the the DT cord-327516-i25whxt2 26 22 proportion proportion NN cord-327516-i25whxt2 26 23 within within IN cord-327516-i25whxt2 26 24 this this DT cord-327516-i25whxt2 26 25 group group NN cord-327516-i25whxt2 26 26 that that WDT cord-327516-i25whxt2 26 27 develop develop VBP cord-327516-i25whxt2 26 28 severe severe JJ cord-327516-i25whxt2 26 29 disease disease NN cord-327516-i25whxt2 26 30 5 5 CD cord-327516-i25whxt2 26 31 . . . cord-327516-i25whxt2 27 1 Such such JJ cord-327516-i25whxt2 27 2 data datum NNS cord-327516-i25whxt2 27 3 are be VBP cord-327516-i25whxt2 27 4 surprisingly surprisingly RB cord-327516-i25whxt2 27 5 hard hard JJ cord-327516-i25whxt2 27 6 to to TO cord-327516-i25whxt2 27 7 gather gather VB cord-327516-i25whxt2 27 8 and and CC cord-327516-i25whxt2 27 9 interpret interpret VB cord-327516-i25whxt2 27 10 because because IN cord-327516-i25whxt2 27 11 care care NN cord-327516-i25whxt2 27 12 - - HYPH cord-327516-i25whxt2 27 13 seeking seeking NN cord-327516-i25whxt2 27 14 and and CC cord-327516-i25whxt2 27 15 care care NN cord-327516-i25whxt2 27 16 - - HYPH cord-327516-i25whxt2 27 17 giving give VBG cord-327516-i25whxt2 27 18 behaviour behaviour NN cord-327516-i25whxt2 27 19 can can MD cord-327516-i25whxt2 27 20 change change VB cord-327516-i25whxt2 27 21 as as IN cord-327516-i25whxt2 27 22 awareness awareness NN cord-327516-i25whxt2 27 23 of of IN cord-327516-i25whxt2 27 24 a a DT cord-327516-i25whxt2 27 25 pandemic pandemic NN cord-327516-i25whxt2 27 26 and and CC cord-327516-i25whxt2 27 27 pressures pressure NNS cord-327516-i25whxt2 27 28 on on IN cord-327516-i25whxt2 27 29 healthcare healthcare NN cord-327516-i25whxt2 27 30 change change NN cord-327516-i25whxt2 27 31 . . . cord-327516-i25whxt2 28 1 This this DT cord-327516-i25whxt2 28 2 is be VBZ cord-327516-i25whxt2 28 3 an an DT cord-327516-i25whxt2 28 4 area area NN cord-327516-i25whxt2 28 5 that that WDT cord-327516-i25whxt2 28 6 requires require VBZ cord-327516-i25whxt2 28 7 investment investment NN cord-327516-i25whxt2 28 8 in in IN cord-327516-i25whxt2 28 9 methodologies methodology NNS cord-327516-i25whxt2 28 10 and and CC cord-327516-i25whxt2 28 11 tools tool NNS cord-327516-i25whxt2 28 12 for for IN cord-327516-i25whxt2 28 13 gathering gather VBG cord-327516-i25whxt2 28 14 the the DT cord-327516-i25whxt2 28 15 necessary necessary JJ cord-327516-i25whxt2 28 16 input input NN cord-327516-i25whxt2 28 17 data datum NNS cord-327516-i25whxt2 28 18 , , , cord-327516-i25whxt2 28 19 including include VBG cord-327516-i25whxt2 28 20 potential potential JJ cord-327516-i25whxt2 28 21 modifying modify VBG cord-327516-i25whxt2 28 22 factors factor NNS cord-327516-i25whxt2 28 23 such such JJ cord-327516-i25whxt2 28 24 as as IN cord-327516-i25whxt2 28 25 care care NN cord-327516-i25whxt2 28 26 - - HYPH cord-327516-i25whxt2 28 27 seeking seek VBG cord-327516-i25whxt2 28 28 behaviour behaviour NN cord-327516-i25whxt2 28 29 , , , cord-327516-i25whxt2 28 30 and and CC cord-327516-i25whxt2 28 31 feeding feed VBG cord-327516-i25whxt2 28 32 that that DT cord-327516-i25whxt2 28 33 data datum NNS cord-327516-i25whxt2 28 34 into into IN cord-327516-i25whxt2 28 35 analytic analytic JJ cord-327516-i25whxt2 28 36 frameworks framework NNS cord-327516-i25whxt2 28 37 for for IN cord-327516-i25whxt2 28 38 estimating estimate VBG cord-327516-i25whxt2 28 39 the the DT cord-327516-i25whxt2 28 40 severity severity NN cord-327516-i25whxt2 28 41 per per IN cord-327516-i25whxt2 28 42 infected infected JJ cord-327516-i25whxt2 28 43 person person NN cord-327516-i25whxt2 28 44 . . . cord-327516-i25whxt2 29 1 Mathematical mathematical JJ cord-327516-i25whxt2 29 2 models model NNS cord-327516-i25whxt2 29 3 of of IN cord-327516-i25whxt2 29 4 disease disease NN cord-327516-i25whxt2 29 5 transmission transmission NN cord-327516-i25whxt2 29 6 have have VBP cord-327516-i25whxt2 29 7 become become VBN cord-327516-i25whxt2 29 8 a a DT cord-327516-i25whxt2 29 9 routine routine JJ cord-327516-i25whxt2 29 10 tool tool NN cord-327516-i25whxt2 29 11 for for IN cord-327516-i25whxt2 29 12 evaluating evaluate VBG cord-327516-i25whxt2 29 13 and and CC cord-327516-i25whxt2 29 14 predicting predict VBG cord-327516-i25whxt2 29 15 the the DT cord-327516-i25whxt2 29 16 behaviour behaviour NN cord-327516-i25whxt2 29 17 of of IN cord-327516-i25whxt2 29 18 epidemics epidemic NNS cord-327516-i25whxt2 29 19 . . . cord-327516-i25whxt2 30 1 These these DT cord-327516-i25whxt2 30 2 models model NNS cord-327516-i25whxt2 30 3 are be VBP cord-327516-i25whxt2 30 4 attractive attractive JJ cord-327516-i25whxt2 30 5 to to IN cord-327516-i25whxt2 30 6 public public JJ cord-327516-i25whxt2 30 7 health health NN cord-327516-i25whxt2 30 8 officials official NNS cord-327516-i25whxt2 30 9 as as IN cord-327516-i25whxt2 30 10 they -PRON- PRP cord-327516-i25whxt2 30 11 provide provide VBP cord-327516-i25whxt2 30 12 a a DT cord-327516-i25whxt2 30 13 quantitative quantitative JJ cord-327516-i25whxt2 30 14 answer answer NN cord-327516-i25whxt2 30 15 to to IN cord-327516-i25whxt2 30 16 many many JJ cord-327516-i25whxt2 30 17 questions question NNS cord-327516-i25whxt2 30 18 , , , cord-327516-i25whxt2 30 19 but but CC cord-327516-i25whxt2 30 20 most most RBS cord-327516-i25whxt2 30 21 importantly importantly RB cord-327516-i25whxt2 30 22 to to IN cord-327516-i25whxt2 30 23 : : : cord-327516-i25whxt2 30 24 " " `` cord-327516-i25whxt2 30 25 how how WRB cord-327516-i25whxt2 30 26 bad bad JJ cord-327516-i25whxt2 30 27 is be VBZ cord-327516-i25whxt2 30 28 this this DT cord-327516-i25whxt2 30 29 and and CC cord-327516-i25whxt2 30 30 how how WRB cord-327516-i25whxt2 30 31 bad bad JJ cord-327516-i25whxt2 30 32 might may MD cord-327516-i25whxt2 30 33 it -PRON- PRP cord-327516-i25whxt2 30 34 get get VB cord-327516-i25whxt2 30 35 ? ? . cord-327516-i25whxt2 31 1 " " '' cord-327516-i25whxt2 32 1 A a DT cord-327516-i25whxt2 32 2 promising promising JJ cord-327516-i25whxt2 32 3 approach approach NN cord-327516-i25whxt2 32 4 to to IN cord-327516-i25whxt2 32 5 even even RB cord-327516-i25whxt2 32 6 faster fast RBR cord-327516-i25whxt2 32 7 and and CC cord-327516-i25whxt2 32 8 more more RBR cord-327516-i25whxt2 32 9 reliable reliable JJ cord-327516-i25whxt2 32 10 characterization characterization NN cord-327516-i25whxt2 32 11 of of IN cord-327516-i25whxt2 32 12 outbreaks outbreak NNS cord-327516-i25whxt2 32 13 is be VBZ cord-327516-i25whxt2 32 14 ' ' `` cord-327516-i25whxt2 32 15 modeldriven modeldriven FW cord-327516-i25whxt2 32 16 data data NNP cord-327516-i25whxt2 32 17 collection collection NNP cord-327516-i25whxt2 32 18 ' ' '' cord-327516-i25whxt2 32 19 , , , cord-327516-i25whxt2 32 20 which which WDT cord-327516-i25whxt2 32 21 tells tell VBZ cord-327516-i25whxt2 32 22 us -PRON- PRP cord-327516-i25whxt2 32 23 " " `` cord-327516-i25whxt2 32 24 how how WRB cord-327516-i25whxt2 32 25 much much JJ cord-327516-i25whxt2 32 26 data datum NNS cord-327516-i25whxt2 32 27 to to TO cord-327516-i25whxt2 32 28 collect collect VB cord-327516-i25whxt2 32 29 and and CC cord-327516-i25whxt2 32 30 when when WRB cord-327516-i25whxt2 32 31 to to TO cord-327516-i25whxt2 32 32 collect collect VB cord-327516-i25whxt2 32 33 it -PRON- PRP cord-327516-i25whxt2 32 34 " " `` cord-327516-i25whxt2 32 35 in in IN cord-327516-i25whxt2 32 36 order order NN cord-327516-i25whxt2 32 37 to to TO cord-327516-i25whxt2 32 38 improve improve VB cord-327516-i25whxt2 32 39 the the DT cord-327516-i25whxt2 32 40 predictive predictive JJ cord-327516-i25whxt2 32 41 power power NN cord-327516-i25whxt2 32 42 of of IN cord-327516-i25whxt2 32 43 the the DT cord-327516-i25whxt2 32 44 models model NNS cord-327516-i25whxt2 32 45 and and CC cord-327516-i25whxt2 32 46 to to TO cord-327516-i25whxt2 32 47 maximize maximize VB cord-327516-i25whxt2 32 48 the the DT cord-327516-i25whxt2 32 49 efficiency efficiency NN cord-327516-i25whxt2 32 50 of of IN cord-327516-i25whxt2 32 51 data datum NNS cord-327516-i25whxt2 32 52 collection collection NN cord-327516-i25whxt2 32 53 6 6 CD cord-327516-i25whxt2 32 54 . . . cord-327516-i25whxt2 33 1 This this DT cord-327516-i25whxt2 33 2 concept concept NN cord-327516-i25whxt2 33 3 should should MD cord-327516-i25whxt2 33 4 be be VB cord-327516-i25whxt2 33 5 tested test VBN cord-327516-i25whxt2 33 6 by by IN cord-327516-i25whxt2 33 7 developing develop VBG cord-327516-i25whxt2 33 8 and and CC cord-327516-i25whxt2 33 9 piloting pilot VBG cord-327516-i25whxt2 33 10 modeldriven modeldriven NNP cord-327516-i25whxt2 33 11 data data NNP cord-327516-i25whxt2 33 12 collection collection NN cord-327516-i25whxt2 33 13 systems system NNS cord-327516-i25whxt2 33 14 for for IN cord-327516-i25whxt2 33 15 seasonal seasonal JJ cord-327516-i25whxt2 33 16 or or CC cord-327516-i25whxt2 33 17 zoonotic zoonotic JJ cord-327516-i25whxt2 33 18 influenza influenza NN cord-327516-i25whxt2 33 19 , , , cord-327516-i25whxt2 33 20 to to TO cord-327516-i25whxt2 33 21 see see VB cord-327516-i25whxt2 33 22 what what WP cord-327516-i25whxt2 33 23 and and CC cord-327516-i25whxt2 33 24 how how WRB cord-327516-i25whxt2 33 25 much much JJ cord-327516-i25whxt2 33 26 data datum NNS cord-327516-i25whxt2 33 27 are be VBP cord-327516-i25whxt2 33 28 needed need VBN cord-327516-i25whxt2 33 29 to to TO cord-327516-i25whxt2 33 30 provide provide VB cord-327516-i25whxt2 33 31 estimates estimate NNS cord-327516-i25whxt2 33 32 of of IN cord-327516-i25whxt2 33 33 the the DT cord-327516-i25whxt2 33 34 severity severity NN cord-327516-i25whxt2 33 35 per per IN cord-327516-i25whxt2 33 36 infected infected JJ cord-327516-i25whxt2 33 37 person person NN cord-327516-i25whxt2 33 38 that that WDT cord-327516-i25whxt2 33 39 are be VBP cord-327516-i25whxt2 33 40 sufficiently sufficiently RB cord-327516-i25whxt2 33 41 reliable reliable JJ cord-327516-i25whxt2 33 42 to to TO cord-327516-i25whxt2 33 43 be be VB cord-327516-i25whxt2 33 44 actionable actionable JJ cord-327516-i25whxt2 33 45 . . . cord-327516-i25whxt2 34 1 The the DT cord-327516-i25whxt2 34 2 world world NN cord-327516-i25whxt2 34 3 population population NN cord-327516-i25whxt2 34 4 is be VBZ cord-327516-i25whxt2 34 5 around around IN cord-327516-i25whxt2 34 6 four four CD cord-327516-i25whxt2 34 7 times time NNS cord-327516-i25whxt2 34 8 the the DT cord-327516-i25whxt2 34 9 size size NN cord-327516-i25whxt2 34 10 it -PRON- PRP cord-327516-i25whxt2 34 11 was be VBD cord-327516-i25whxt2 34 12 in in IN cord-327516-i25whxt2 34 13 1918 1918 CD cord-327516-i25whxt2 34 14 , , , cord-327516-i25whxt2 34 15 and and CC cord-327516-i25whxt2 34 16 the the DT cord-327516-i25whxt2 34 17 mobility mobility NN cord-327516-i25whxt2 34 18 of of IN cord-327516-i25whxt2 34 19 this this DT cord-327516-i25whxt2 34 20 population population NN cord-327516-i25whxt2 34 21 is be VBZ cord-327516-i25whxt2 34 22 massively massively RB cord-327516-i25whxt2 34 23 increased increase VBN cord-327516-i25whxt2 34 24 4 4 CD cord-327516-i25whxt2 34 25 . . . cord-327516-i25whxt2 35 1 If if IN cord-327516-i25whxt2 35 2 a a DT cord-327516-i25whxt2 35 3 potential potential JJ cord-327516-i25whxt2 35 4 pandemic pandemic NN cord-327516-i25whxt2 35 5 influenza influenza NN cord-327516-i25whxt2 35 6 virus virus NN cord-327516-i25whxt2 35 7 acquires acquire VBZ cord-327516-i25whxt2 35 8 the the DT cord-327516-i25whxt2 35 9 ability ability NN cord-327516-i25whxt2 35 10 to to TO cord-327516-i25whxt2 35 11 readily readily RB cord-327516-i25whxt2 35 12 transmit transmit VB cord-327516-i25whxt2 35 13 between between IN cord-327516-i25whxt2 35 14 humans human NNS cord-327516-i25whxt2 35 15 , , , cord-327516-i25whxt2 35 16 it -PRON- PRP cord-327516-i25whxt2 35 17 will will MD cord-327516-i25whxt2 35 18 spread spread VB cord-327516-i25whxt2 35 19 with with IN cord-327516-i25whxt2 35 20 alarming alarming JJ cord-327516-i25whxt2 35 21 speed speed NN cord-327516-i25whxt2 35 22 and and CC cord-327516-i25whxt2 35 23 essentially essentially RB cord-327516-i25whxt2 35 24 become become VB cord-327516-i25whxt2 35 25 unstoppable unstoppable JJ cord-327516-i25whxt2 35 26 . . . cord-327516-i25whxt2 36 1 Aeroplane aeroplane NN cord-327516-i25whxt2 36 2 transportation transportation NN cord-327516-i25whxt2 36 3 is be VBZ cord-327516-i25whxt2 36 4 the the DT cord-327516-i25whxt2 36 5 greatest great JJS cord-327516-i25whxt2 36 6 facilitator facilitator NN cord-327516-i25whxt2 36 7 of of IN cord-327516-i25whxt2 36 8 rapid rapid JJ cord-327516-i25whxt2 36 9 global global JJ cord-327516-i25whxt2 36 10 spread spread NN cord-327516-i25whxt2 36 11 7 7 CD cord-327516-i25whxt2 36 12 , , , cord-327516-i25whxt2 36 13 yet yet CC cord-327516-i25whxt2 36 14 airport airport NN cord-327516-i25whxt2 36 15 screening screening NN cord-327516-i25whxt2 36 16 has have VBZ cord-327516-i25whxt2 36 17 limited limit VBN cord-327516-i25whxt2 36 18 ability ability NN cord-327516-i25whxt2 36 19 to to TO cord-327516-i25whxt2 36 20 prevent prevent VB cord-327516-i25whxt2 36 21 importation importation NN cord-327516-i25whxt2 36 22 and and CC cord-327516-i25whxt2 36 23 at at IN cord-327516-i25whxt2 36 24 best good JJS cord-327516-i25whxt2 36 25 can can MD cord-327516-i25whxt2 36 26 lead lead VB cord-327516-i25whxt2 36 27 to to IN cord-327516-i25whxt2 36 28 a a DT cord-327516-i25whxt2 36 29 short short JJ cord-327516-i25whxt2 36 30 delay delay NN cord-327516-i25whxt2 36 31 ( ( -LRB- cord-327516-i25whxt2 36 32 less less JJR cord-327516-i25whxt2 36 33 than than IN cord-327516-i25whxt2 36 34 two two CD cord-327516-i25whxt2 36 35 weeks week NNS cord-327516-i25whxt2 36 36 ) ) -RRB- cord-327516-i25whxt2 36 37 in in IN cord-327516-i25whxt2 36 38 the the DT cord-327516-i25whxt2 36 39 onset onset NN cord-327516-i25whxt2 36 40 of of IN cord-327516-i25whxt2 36 41 local local JJ cord-327516-i25whxt2 36 42 transmission transmission NN cord-327516-i25whxt2 36 43 8 8 CD cord-327516-i25whxt2 36 44 , , , cord-327516-i25whxt2 36 45 9 9 CD cord-327516-i25whxt2 36 46 . . . cord-327516-i25whxt2 37 1 At at IN cord-327516-i25whxt2 37 2 a a DT cord-327516-i25whxt2 37 3 national national JJ cord-327516-i25whxt2 37 4 level level NN cord-327516-i25whxt2 37 5 , , , cord-327516-i25whxt2 37 6 measures measure NNS cord-327516-i25whxt2 37 7 to to TO cord-327516-i25whxt2 37 8 limit limit VB cord-327516-i25whxt2 37 9 local local JJ cord-327516-i25whxt2 37 10 transmission transmission NN cord-327516-i25whxt2 37 11 , , , cord-327516-i25whxt2 37 12 such such JJ cord-327516-i25whxt2 37 13 as as IN cord-327516-i25whxt2 37 14 school school NN cord-327516-i25whxt2 37 15 closure closure NN cord-327516-i25whxt2 37 16 , , , cord-327516-i25whxt2 37 17 can can MD cord-327516-i25whxt2 37 18 have have VB cord-327516-i25whxt2 37 19 some some DT cord-327516-i25whxt2 37 20 effect effect NN cord-327516-i25whxt2 37 21 in in IN cord-327516-i25whxt2 37 22 reducing reduce VBG cord-327516-i25whxt2 37 23 community community NN cord-327516-i25whxt2 37 24 transmission transmission NN cord-327516-i25whxt2 37 25 and and CC cord-327516-i25whxt2 37 26 can can MD cord-327516-i25whxt2 37 27 mitigate mitigate VB cord-327516-i25whxt2 37 28 pressures pressure NNS cord-327516-i25whxt2 37 29 on on IN cord-327516-i25whxt2 37 30 the the DT cord-327516-i25whxt2 37 31 healthcare healthcare NN cord-327516-i25whxt2 37 32 system system NN cord-327516-i25whxt2 37 33 by by IN cord-327516-i25whxt2 37 34 reducing reduce VBG cord-327516-i25whxt2 37 35 peak peak NN cord-327516-i25whxt2 37 36 incidence incidence NN cord-327516-i25whxt2 37 37 . . . cord-327516-i25whxt2 38 1 The the DT cord-327516-i25whxt2 38 2 effect effect NN cord-327516-i25whxt2 38 3 is be VBZ cord-327516-i25whxt2 38 4 , , , cord-327516-i25whxt2 38 5 however however RB cord-327516-i25whxt2 38 6 , , , cord-327516-i25whxt2 38 7 dependent dependent JJ cord-327516-i25whxt2 38 8 on on IN cord-327516-i25whxt2 38 9 timing timing NN cord-327516-i25whxt2 38 10 and and CC cord-327516-i25whxt2 38 11 coordination coordination NN cord-327516-i25whxt2 38 12 and and CC cord-327516-i25whxt2 38 13 therefore therefore RB cord-327516-i25whxt2 38 14 requires require VBZ cord-327516-i25whxt2 38 15 access access NN cord-327516-i25whxt2 38 16 to to IN cord-327516-i25whxt2 38 17 real real JJ cord-327516-i25whxt2 38 18 - - HYPH cord-327516-i25whxt2 38 19 time time NN cord-327516-i25whxt2 38 20 surveillance surveillance NN cord-327516-i25whxt2 38 21 data datum NNS cord-327516-i25whxt2 38 22 , , , cord-327516-i25whxt2 38 23 such such JJ cord-327516-i25whxt2 38 24 as as IN cord-327516-i25whxt2 38 25 absenteeism absenteeism NN cord-327516-i25whxt2 38 26 10 10 CD cord-327516-i25whxt2 38 27 , , , cord-327516-i25whxt2 38 28 11 11 CD cord-327516-i25whxt2 38 29 . . . cord-327516-i25whxt2 39 1 The the DT cord-327516-i25whxt2 39 2 simultaneous simultaneous JJ cord-327516-i25whxt2 39 3 use use NN cord-327516-i25whxt2 39 4 of of IN cord-327516-i25whxt2 39 5 face face NN cord-327516-i25whxt2 39 6 comment comment NN cord-327516-i25whxt2 39 7 masks mask NNS cord-327516-i25whxt2 39 8 and and CC cord-327516-i25whxt2 39 9 hand hand NN cord-327516-i25whxt2 39 10 hygiene hygiene NN cord-327516-i25whxt2 39 11 together together RB cord-327516-i25whxt2 39 12 , , , cord-327516-i25whxt2 39 13 targeting target VBG cord-327516-i25whxt2 39 14 both both CC cord-327516-i25whxt2 39 15 aerosol aerosol NN cord-327516-i25whxt2 39 16 and and CC cord-327516-i25whxt2 39 17 contact contact NN cord-327516-i25whxt2 39 18 transmission transmission NN cord-327516-i25whxt2 39 19 , , , cord-327516-i25whxt2 39 20 can can MD cord-327516-i25whxt2 39 21 reduce reduce VB cord-327516-i25whxt2 39 22 spread spread VBN cord-327516-i25whxt2 39 23 under under IN cord-327516-i25whxt2 39 24 laboratory laboratory NN cord-327516-i25whxt2 39 25 conditions condition NNS cord-327516-i25whxt2 39 26 , , , cord-327516-i25whxt2 39 27 although although IN cord-327516-i25whxt2 39 28 the the DT cord-327516-i25whxt2 39 29 effectiveness effectiveness NN cord-327516-i25whxt2 39 30 of of IN cord-327516-i25whxt2 39 31 these these DT cord-327516-i25whxt2 39 32 measures measure NNS cord-327516-i25whxt2 39 33 as as IN cord-327516-i25whxt2 39 34 a a DT cord-327516-i25whxt2 39 35 community community NN cord-327516-i25whxt2 39 36 - - HYPH cord-327516-i25whxt2 39 37 wide wide JJ cord-327516-i25whxt2 39 38 intervention intervention NN cord-327516-i25whxt2 39 39 is be VBZ cord-327516-i25whxt2 39 40 unproven unproven JJ cord-327516-i25whxt2 39 41 12 12 CD cord-327516-i25whxt2 39 42 . . . cord-327516-i25whxt2 40 1 Whilst whilst IN cord-327516-i25whxt2 40 2 neuraminidase neuraminidase NN cord-327516-i25whxt2 40 3 inhibitors inhibitor NNS cord-327516-i25whxt2 40 4 ( ( -LRB- cord-327516-i25whxt2 40 5 NAIs nai NNS cord-327516-i25whxt2 40 6 ) ) -RRB- cord-327516-i25whxt2 40 7 have have VBP cord-327516-i25whxt2 40 8 been be VBN cord-327516-i25whxt2 40 9 demonstrated demonstrate VBN cord-327516-i25whxt2 40 10 to to TO cord-327516-i25whxt2 40 11 be be VB cord-327516-i25whxt2 40 12 effective effective JJ cord-327516-i25whxt2 40 13 in in IN cord-327516-i25whxt2 40 14 reducing reduce VBG cord-327516-i25whxt2 40 15 symptomatic symptomatic JJ cord-327516-i25whxt2 40 16 influenza influenza NN cord-327516-i25whxt2 40 17 and and CC cord-327516-i25whxt2 40 18 intra intra JJ cord-327516-i25whxt2 40 19 - - JJ cord-327516-i25whxt2 40 20 household household JJ cord-327516-i25whxt2 40 21 transmission transmission NN cord-327516-i25whxt2 40 22 when when WRB cord-327516-i25whxt2 40 23 used use VBN cord-327516-i25whxt2 40 24 prophylactically prophylactically RB cord-327516-i25whxt2 40 25 , , , cord-327516-i25whxt2 40 26 there there EX cord-327516-i25whxt2 40 27 are be VBP cord-327516-i25whxt2 40 28 no no DT cord-327516-i25whxt2 40 29 data datum NNS cord-327516-i25whxt2 40 30 on on IN cord-327516-i25whxt2 40 31 the the DT cord-327516-i25whxt2 40 32 effectiveness effectiveness NN cord-327516-i25whxt2 40 33 or or CC cord-327516-i25whxt2 40 34 cost cost NN cord-327516-i25whxt2 40 35 effectiveness effectiveness NN cord-327516-i25whxt2 40 36 of of IN cord-327516-i25whxt2 40 37 NAI NAI NNP cord-327516-i25whxt2 40 38 use use NN cord-327516-i25whxt2 40 39 in in IN cord-327516-i25whxt2 40 40 reducing reduce VBG cord-327516-i25whxt2 40 41 community community NN cord-327516-i25whxt2 40 42 - - HYPH cord-327516-i25whxt2 40 43 wide wide JJ cord-327516-i25whxt2 40 44 transmission transmission NN cord-327516-i25whxt2 40 45 13 13 CD cord-327516-i25whxt2 40 46 . . . cord-327516-i25whxt2 41 1 Therefore therefore RB cord-327516-i25whxt2 41 2 , , , cord-327516-i25whxt2 41 3 the the DT cord-327516-i25whxt2 41 4 stockpiling stockpiling NN cord-327516-i25whxt2 41 5 of of IN cord-327516-i25whxt2 41 6 NAIs nai NNS cord-327516-i25whxt2 41 7 by by IN cord-327516-i25whxt2 41 8 individual individual JJ cord-327516-i25whxt2 41 9 countries country NNS cord-327516-i25whxt2 41 10 could could MD cord-327516-i25whxt2 41 11 permit permit VB cord-327516-i25whxt2 41 12 prophylactic prophylactic JJ cord-327516-i25whxt2 41 13 use use NN cord-327516-i25whxt2 41 14 that that WDT cord-327516-i25whxt2 41 15 may may MD cord-327516-i25whxt2 41 16 reduce reduce VB cord-327516-i25whxt2 41 17 the the DT cord-327516-i25whxt2 41 18 local local JJ cord-327516-i25whxt2 41 19 impact impact NN cord-327516-i25whxt2 41 20 of of IN cord-327516-i25whxt2 41 21 a a DT cord-327516-i25whxt2 41 22 pandemic pandemic NN cord-327516-i25whxt2 41 23 , , , cord-327516-i25whxt2 41 24 but but CC cord-327516-i25whxt2 41 25 at at IN cord-327516-i25whxt2 41 26 the the DT cord-327516-i25whxt2 41 27 global global JJ cord-327516-i25whxt2 41 28 level level NN cord-327516-i25whxt2 41 29 NAIs nai NNS cord-327516-i25whxt2 41 30 are be VBP cord-327516-i25whxt2 41 31 not not RB cord-327516-i25whxt2 41 32 likely likely JJ cord-327516-i25whxt2 41 33 to to TO cord-327516-i25whxt2 41 34 have have VB cord-327516-i25whxt2 41 35 a a DT cord-327516-i25whxt2 41 36 significant significant JJ cord-327516-i25whxt2 41 37 role role NN cord-327516-i25whxt2 41 38 in in IN cord-327516-i25whxt2 41 39 reducing reduce VBG cord-327516-i25whxt2 41 40 pandemic pandemic NN cord-327516-i25whxt2 41 41 influenza influenza NN cord-327516-i25whxt2 41 42 transmission transmission NN cord-327516-i25whxt2 41 43 . . . cord-327516-i25whxt2 42 1 Around around IN cord-327516-i25whxt2 42 2 half half NN cord-327516-i25whxt2 42 3 of of IN cord-327516-i25whxt2 42 4 the the DT cord-327516-i25whxt2 42 5 world world NN cord-327516-i25whxt2 42 6 's 's POS cord-327516-i25whxt2 42 7 population population NN cord-327516-i25whxt2 42 8 lacks lack VBZ cord-327516-i25whxt2 42 9 full full JJ cord-327516-i25whxt2 42 10 access access NN cord-327516-i25whxt2 42 11 to to IN cord-327516-i25whxt2 42 12 essential essential JJ cord-327516-i25whxt2 42 13 health health NN cord-327516-i25whxt2 42 14 services service NNS cord-327516-i25whxt2 42 15 14 14 CD cord-327516-i25whxt2 42 16 . . . cord-327516-i25whxt2 43 1 It -PRON- PRP cord-327516-i25whxt2 43 2 is be VBZ cord-327516-i25whxt2 43 3 therefore therefore RB cord-327516-i25whxt2 43 4 not not RB cord-327516-i25whxt2 43 5 surprising surprising JJ cord-327516-i25whxt2 43 6 that that IN cord-327516-i25whxt2 43 7 the the DT cord-327516-i25whxt2 43 8 burden burden NN cord-327516-i25whxt2 43 9 of of IN cord-327516-i25whxt2 43 10 influenza influenza NN cord-327516-i25whxt2 43 11 is be VBZ cord-327516-i25whxt2 43 12 greater great JJR cord-327516-i25whxt2 43 13 in in IN cord-327516-i25whxt2 43 14 low low JJ cord-327516-i25whxt2 43 15 - - : cord-327516-i25whxt2 43 16 and and CC cord-327516-i25whxt2 43 17 middleincome middleincome NNP cord-327516-i25whxt2 43 18 countries country NNS cord-327516-i25whxt2 43 19 ( ( -LRB- cord-327516-i25whxt2 43 20 LMICs lmic NNS cord-327516-i25whxt2 43 21 ) ) -RRB- cord-327516-i25whxt2 43 22 than than IN cord-327516-i25whxt2 43 23 in in IN cord-327516-i25whxt2 43 24 highincome highincome NNP cord-327516-i25whxt2 43 25 countries country NNS cord-327516-i25whxt2 43 26 . . . cord-327516-i25whxt2 44 1 In in IN cord-327516-i25whxt2 44 2 the the DT cord-327516-i25whxt2 44 3 2009 2009 CD cord-327516-i25whxt2 44 4 pandemic pandemic NN cord-327516-i25whxt2 44 5 , , , cord-327516-i25whxt2 44 6 the the DT cord-327516-i25whxt2 44 7 estimated estimate VBN cord-327516-i25whxt2 44 8 death death NN cord-327516-i25whxt2 44 9 rate rate NN cord-327516-i25whxt2 44 10 in in IN cord-327516-i25whxt2 44 11 Africa Africa NNP cord-327516-i25whxt2 44 12 was be VBD cord-327516-i25whxt2 44 13 2 2 CD cord-327516-i25whxt2 44 14 - - SYM cord-327516-i25whxt2 44 15 4 4 CD cord-327516-i25whxt2 44 16 times time NNS cord-327516-i25whxt2 44 17 that that DT cord-327516-i25whxt2 44 18 of of IN cord-327516-i25whxt2 44 19 other other JJ cord-327516-i25whxt2 44 20 regions region NNS cord-327516-i25whxt2 44 21 15 15 CD cord-327516-i25whxt2 44 22 , , , cord-327516-i25whxt2 44 23 whilst whilst IN cord-327516-i25whxt2 44 24 mortality mortality NN cord-327516-i25whxt2 44 25 rates rate NNS cord-327516-i25whxt2 44 26 for for IN cord-327516-i25whxt2 44 27 influenza influenza NN cord-327516-i25whxt2 44 28 - - HYPH cord-327516-i25whxt2 44 29 associated associate VBN cord-327516-i25whxt2 44 30 acute acute JJ cord-327516-i25whxt2 44 31 lower low JJR cord-327516-i25whxt2 44 32 respiratory respiratory JJ cord-327516-i25whxt2 44 33 tract tract NN cord-327516-i25whxt2 44 34 infection infection NN cord-327516-i25whxt2 44 35 in in IN cord-327516-i25whxt2 44 36 children child NNS cord-327516-i25whxt2 44 37 younger young JJR cord-327516-i25whxt2 44 38 than than IN cord-327516-i25whxt2 44 39 5 5 CD cord-327516-i25whxt2 44 40 years year NNS cord-327516-i25whxt2 44 41 are be VBP cord-327516-i25whxt2 44 42 three three CD cord-327516-i25whxt2 44 43 times time NNS cord-327516-i25whxt2 44 44 higher high JJR cord-327516-i25whxt2 44 45 in in IN cord-327516-i25whxt2 44 46 low low JJ cord-327516-i25whxt2 44 47 - - HYPH cord-327516-i25whxt2 44 48 income income NN cord-327516-i25whxt2 44 49 countries country NNS cord-327516-i25whxt2 44 50 than than IN cord-327516-i25whxt2 44 51 in in IN cord-327516-i25whxt2 44 52 high high JJ cord-327516-i25whxt2 44 53 - - HYPH cord-327516-i25whxt2 44 54 income income NN cord-327516-i25whxt2 44 55 countries country NNS cord-327516-i25whxt2 44 56 16 16 CD cord-327516-i25whxt2 44 57 . . . cord-327516-i25whxt2 45 1 The the DT cord-327516-i25whxt2 45 2 influenzaassociated influenzaassociated JJ cord-327516-i25whxt2 45 3 death death NN cord-327516-i25whxt2 45 4 rate rate NN cord-327516-i25whxt2 45 5 in in IN cord-327516-i25whxt2 45 6 the the DT cord-327516-i25whxt2 45 7 elderly elderly JJ cord-327516-i25whxt2 45 8 is be VBZ cord-327516-i25whxt2 45 9 also also RB cord-327516-i25whxt2 45 10 likely likely JJ cord-327516-i25whxt2 45 11 to to TO cord-327516-i25whxt2 45 12 be be VB cord-327516-i25whxt2 45 13 substantially substantially RB cord-327516-i25whxt2 45 14 increased increase VBN cord-327516-i25whxt2 45 15 in in IN cord-327516-i25whxt2 45 16 LMICs lmic NNS cord-327516-i25whxt2 45 17 compared compare VBN cord-327516-i25whxt2 45 18 to to IN cord-327516-i25whxt2 45 19 higher high JJR cord-327516-i25whxt2 45 20 - - HYPH cord-327516-i25whxt2 45 21 income income NN cord-327516-i25whxt2 45 22 countries country NNS cord-327516-i25whxt2 45 23 17 17 CD cord-327516-i25whxt2 45 24 . . . cord-327516-i25whxt2 46 1 This this DT cord-327516-i25whxt2 46 2 burden burden NN cord-327516-i25whxt2 46 3 of of IN cord-327516-i25whxt2 46 4 influenza influenza NN cord-327516-i25whxt2 46 5 in in IN cord-327516-i25whxt2 46 6 LMICs lmic NNS cord-327516-i25whxt2 46 7 is be VBZ cord-327516-i25whxt2 46 8 often often RB cord-327516-i25whxt2 46 9 unrecognized unrecognized JJ cord-327516-i25whxt2 46 10 , , , cord-327516-i25whxt2 46 11 particularly particularly RB cord-327516-i25whxt2 46 12 in in IN cord-327516-i25whxt2 46 13 rural rural JJ cord-327516-i25whxt2 46 14 areas area NNS cord-327516-i25whxt2 46 15 18 18 CD cord-327516-i25whxt2 46 16 , , , cord-327516-i25whxt2 46 17 19 19 CD cord-327516-i25whxt2 46 18 . . . cord-327516-i25whxt2 47 1 Any any DT cord-327516-i25whxt2 47 2 assessment assessment NN cord-327516-i25whxt2 47 3 of of IN cord-327516-i25whxt2 47 4 our -PRON- PRP$ cord-327516-i25whxt2 47 5 ability ability NN cord-327516-i25whxt2 47 6 to to TO cord-327516-i25whxt2 47 7 mitigate mitigate VB cord-327516-i25whxt2 47 8 the the DT cord-327516-i25whxt2 47 9 health health NN cord-327516-i25whxt2 47 10 impact impact NN cord-327516-i25whxt2 47 11 of of IN cord-327516-i25whxt2 47 12 the the DT cord-327516-i25whxt2 47 13 next next JJ cord-327516-i25whxt2 47 14 influenza influenza NN cord-327516-i25whxt2 47 15 pandemic pandemic NN cord-327516-i25whxt2 47 16 must must MD cord-327516-i25whxt2 47 17 consider consider VB cord-327516-i25whxt2 47 18 what what WP cord-327516-i25whxt2 47 19 will will MD cord-327516-i25whxt2 47 20 be be VB cord-327516-i25whxt2 47 21 available available JJ cord-327516-i25whxt2 47 22 for for IN cord-327516-i25whxt2 47 23 the the DT cord-327516-i25whxt2 47 24 large large JJ cord-327516-i25whxt2 47 25 and and CC cord-327516-i25whxt2 47 26 vulnerable vulnerable JJ cord-327516-i25whxt2 47 27 populations population NNS cord-327516-i25whxt2 47 28 living live VBG cord-327516-i25whxt2 47 29 in in IN cord-327516-i25whxt2 47 30 LMICs lmic NNS cord-327516-i25whxt2 47 31 . . . cord-327516-i25whxt2 48 1 The the DT cord-327516-i25whxt2 48 2 therapeutic therapeutic JJ cord-327516-i25whxt2 48 3 efficacy efficacy NN cord-327516-i25whxt2 48 4 of of IN cord-327516-i25whxt2 48 5 NAIs nai NNS cord-327516-i25whxt2 48 6 is be VBZ cord-327516-i25whxt2 48 7 a a DT cord-327516-i25whxt2 48 8 matter matter NN cord-327516-i25whxt2 48 9 of of IN cord-327516-i25whxt2 48 10 some some DT cord-327516-i25whxt2 48 11 debate debate NN cord-327516-i25whxt2 48 12 , , , cord-327516-i25whxt2 48 13 but but CC cord-327516-i25whxt2 48 14 can can MD cord-327516-i25whxt2 48 15 probably probably RB cord-327516-i25whxt2 48 16 be be VB cord-327516-i25whxt2 48 17 summarized summarize VBN cord-327516-i25whxt2 48 18 as as IN cord-327516-i25whxt2 48 19 a a DT cord-327516-i25whxt2 48 20 proven prove VBN cord-327516-i25whxt2 48 21 but but CC cord-327516-i25whxt2 48 22 modest modest JJ cord-327516-i25whxt2 48 23 effect effect NN cord-327516-i25whxt2 48 24 on on IN cord-327516-i25whxt2 48 25 the the DT cord-327516-i25whxt2 48 26 duration duration NN cord-327516-i25whxt2 48 27 of of IN cord-327516-i25whxt2 48 28 symptoms symptom NNS cord-327516-i25whxt2 48 29 in in IN cord-327516-i25whxt2 48 30 patients patient NNS cord-327516-i25whxt2 48 31 with with IN cord-327516-i25whxt2 48 32 mild mild JJ cord-327516-i25whxt2 48 33 influenza influenza NN cord-327516-i25whxt2 48 34 , , , cord-327516-i25whxt2 48 35 and and CC cord-327516-i25whxt2 48 36 a a DT cord-327516-i25whxt2 48 37 probable probable JJ cord-327516-i25whxt2 48 38 but but CC cord-327516-i25whxt2 48 39 unproven unproven JJ cord-327516-i25whxt2 48 40 small small JJ cord-327516-i25whxt2 48 41 reduction reduction NN cord-327516-i25whxt2 48 42 in in IN cord-327516-i25whxt2 48 43 severe severe JJ cord-327516-i25whxt2 48 44 outcomes outcome NNS cord-327516-i25whxt2 48 45 such such JJ cord-327516-i25whxt2 48 46 as as IN cord-327516-i25whxt2 48 47 pneumonia pneumonia NN cord-327516-i25whxt2 48 48 and and CC cord-327516-i25whxt2 48 49 death death NN cord-327516-i25whxt2 48 50 . . . cord-327516-i25whxt2 49 1 Given give VBN cord-327516-i25whxt2 49 2 the the DT cord-327516-i25whxt2 49 3 weak weak JJ cord-327516-i25whxt2 49 4 evidence evidence NN cord-327516-i25whxt2 49 5 of of IN cord-327516-i25whxt2 49 6 an an DT cord-327516-i25whxt2 49 7 impact impact NN cord-327516-i25whxt2 49 8 on on IN cord-327516-i25whxt2 49 9 severe severe JJ cord-327516-i25whxt2 49 10 outcomes outcome NNS cord-327516-i25whxt2 49 11 , , , cord-327516-i25whxt2 49 12 the the DT cord-327516-i25whxt2 49 13 NAI NAI NNP cord-327516-i25whxt2 49 14 oseltamivir oseltamivir NN cord-327516-i25whxt2 49 15 has have VBZ cord-327516-i25whxt2 49 16 recently recently RB cord-327516-i25whxt2 49 17 been be VBN cord-327516-i25whxt2 49 18 ' ' `` cord-327516-i25whxt2 49 19 downgraded downgrade VBN cord-327516-i25whxt2 49 20 ' ' '' cord-327516-i25whxt2 49 21 to to IN cord-327516-i25whxt2 49 22 the the DT cord-327516-i25whxt2 49 23 complementary complementary JJ cord-327516-i25whxt2 49 24 part part NN cord-327516-i25whxt2 49 25 of of IN cord-327516-i25whxt2 49 26 the the DT cord-327516-i25whxt2 49 27 WHO WHO NNP cord-327516-i25whxt2 49 28 Essential Essential NNP cord-327516-i25whxt2 49 29 Medicines Medicines NNP cord-327516-i25whxt2 49 30 List List NNP cord-327516-i25whxt2 49 31 , , , cord-327516-i25whxt2 49 32 only only RB cord-327516-i25whxt2 49 33 to to TO cord-327516-i25whxt2 49 34 be be VB cord-327516-i25whxt2 49 35 used use VBN cord-327516-i25whxt2 49 36 for for IN cord-327516-i25whxt2 49 37 critically critically RB cord-327516-i25whxt2 49 38 ill ill JJ cord-327516-i25whxt2 49 39 patients patient NNS cord-327516-i25whxt2 49 40 hospitalized hospitalize VBN cord-327516-i25whxt2 49 41 with with IN cord-327516-i25whxt2 49 42 influenza influenza NN cord-327516-i25whxt2 49 43 20 20 CD cord-327516-i25whxt2 49 44 . . . cord-327516-i25whxt2 50 1 It -PRON- PRP cord-327516-i25whxt2 50 2 is be VBZ cord-327516-i25whxt2 50 3 , , , cord-327516-i25whxt2 50 4 therefore therefore RB cord-327516-i25whxt2 50 5 , , , cord-327516-i25whxt2 50 6 hard hard JJ cord-327516-i25whxt2 50 7 to to TO cord-327516-i25whxt2 50 8 see see VB cord-327516-i25whxt2 50 9 NAIs nai NNS cord-327516-i25whxt2 50 10 having have VBG cord-327516-i25whxt2 50 11 a a DT cord-327516-i25whxt2 50 12 significant significant JJ cord-327516-i25whxt2 50 13 global global JJ cord-327516-i25whxt2 50 14 impact impact NN cord-327516-i25whxt2 50 15 on on IN cord-327516-i25whxt2 50 16 the the DT cord-327516-i25whxt2 50 17 rate rate NN cord-327516-i25whxt2 50 18 of of IN cord-327516-i25whxt2 50 19 hospitalization hospitalization NN cord-327516-i25whxt2 50 20 or or CC cord-327516-i25whxt2 50 21 death death NN cord-327516-i25whxt2 50 22 in in IN cord-327516-i25whxt2 50 23 any any DT cord-327516-i25whxt2 50 24 future future JJ cord-327516-i25whxt2 50 25 pandemic pandemic NN cord-327516-i25whxt2 50 26 . . . cord-327516-i25whxt2 51 1 In in IN cord-327516-i25whxt2 51 2 addition addition NN cord-327516-i25whxt2 51 3 to to IN cord-327516-i25whxt2 51 4 the the DT cord-327516-i25whxt2 51 5 weak weak JJ cord-327516-i25whxt2 51 6 evidence evidence NN cord-327516-i25whxt2 51 7 of of IN cord-327516-i25whxt2 51 8 an an DT cord-327516-i25whxt2 51 9 impact impact NN cord-327516-i25whxt2 51 10 on on IN cord-327516-i25whxt2 51 11 severe severe JJ cord-327516-i25whxt2 51 12 outcomes outcome NNS cord-327516-i25whxt2 51 13 , , , cord-327516-i25whxt2 51 14 the the DT cord-327516-i25whxt2 51 15 existence existence NN cord-327516-i25whxt2 51 16 of of IN cord-327516-i25whxt2 51 17 viral viral JJ cord-327516-i25whxt2 51 18 genetic genetic JJ cord-327516-i25whxt2 51 19 variants variant NNS cord-327516-i25whxt2 51 20 that that WDT cord-327516-i25whxt2 51 21 confer confer VBP cord-327516-i25whxt2 51 22 considerable considerable JJ cord-327516-i25whxt2 51 23 resistance resistance NN cord-327516-i25whxt2 51 24 to to IN cord-327516-i25whxt2 51 25 NAIs nai NNS cord-327516-i25whxt2 51 26 make make VBP cord-327516-i25whxt2 51 27 it -PRON- PRP cord-327516-i25whxt2 51 28 clear clear JJ cord-327516-i25whxt2 51 29 that that IN cord-327516-i25whxt2 51 30 new new JJ cord-327516-i25whxt2 51 31 antivirals antiviral NNS cord-327516-i25whxt2 51 32 for for IN cord-327516-i25whxt2 51 33 influenza influenza NN cord-327516-i25whxt2 51 34 are be VBP cord-327516-i25whxt2 51 35 needed need VBN cord-327516-i25whxt2 51 36 . . . cord-327516-i25whxt2 52 1 There there EX cord-327516-i25whxt2 52 2 are be VBP cord-327516-i25whxt2 52 3 candidates candidate NNS cord-327516-i25whxt2 52 4 in in IN cord-327516-i25whxt2 52 5 clinical clinical JJ cord-327516-i25whxt2 52 6 development development NN cord-327516-i25whxt2 52 7 but but CC cord-327516-i25whxt2 52 8 progress progress NN cord-327516-i25whxt2 52 9 is be VBZ cord-327516-i25whxt2 52 10 slow slow JJ cord-327516-i25whxt2 52 11 , , , cord-327516-i25whxt2 52 12 and and CC cord-327516-i25whxt2 52 13 companies company NNS cord-327516-i25whxt2 52 14 have have VBP cord-327516-i25whxt2 52 15 favoured favour VBN cord-327516-i25whxt2 52 16 evaluating evaluate VBG cord-327516-i25whxt2 52 17 new new JJ cord-327516-i25whxt2 52 18 candidate candidate NN cord-327516-i25whxt2 52 19 drugs drug NNS cord-327516-i25whxt2 52 20 in in IN cord-327516-i25whxt2 52 21 patients patient NNS cord-327516-i25whxt2 52 22 with with IN cord-327516-i25whxt2 52 23 uncomplicated uncomplicated JJ cord-327516-i25whxt2 52 24 influenza influenza NN cord-327516-i25whxt2 52 25 , , , cord-327516-i25whxt2 52 26 since since IN cord-327516-i25whxt2 52 27 this this DT cord-327516-i25whxt2 52 28 is be VBZ cord-327516-i25whxt2 52 29 the the DT cord-327516-i25whxt2 52 30 bigger big JJR cord-327516-i25whxt2 52 31 market market NN cord-327516-i25whxt2 52 32 . . . cord-327516-i25whxt2 53 1 What what WP cord-327516-i25whxt2 53 2 is be VBZ cord-327516-i25whxt2 53 3 needed need VBN cord-327516-i25whxt2 53 4 is be VBZ cord-327516-i25whxt2 53 5 a a DT cord-327516-i25whxt2 53 6 large large JJ cord-327516-i25whxt2 53 7 influenza influenza NN cord-327516-i25whxt2 53 8 clinical clinical JJ cord-327516-i25whxt2 53 9 trials trial NNS cord-327516-i25whxt2 53 10 network network NN cord-327516-i25whxt2 53 11 that that WDT cord-327516-i25whxt2 53 12 can can MD cord-327516-i25whxt2 53 13 evaluate evaluate VB cord-327516-i25whxt2 53 14 multiple multiple JJ cord-327516-i25whxt2 53 15 candidates candidate NNS cord-327516-i25whxt2 53 16 and and CC cord-327516-i25whxt2 53 17 combination combination NN cord-327516-i25whxt2 53 18 therapies therapy NNS cord-327516-i25whxt2 53 19 ( ( -LRB- cord-327516-i25whxt2 53 20 including include VBG cord-327516-i25whxt2 53 21 antiviral antiviral JJ cord-327516-i25whxt2 53 22 combinations combination NNS cord-327516-i25whxt2 53 23 and and CC cord-327516-i25whxt2 53 24 host host NN cord-327516-i25whxt2 53 25 - - HYPH cord-327516-i25whxt2 53 26 directed direct VBN cord-327516-i25whxt2 53 27 therapies therapy NNS cord-327516-i25whxt2 53 28 ) ) -RRB- cord-327516-i25whxt2 53 29 in in IN cord-327516-i25whxt2 53 30 an an DT cord-327516-i25whxt2 53 31 adaptive adaptive JJ cord-327516-i25whxt2 53 32 platform platform NN cord-327516-i25whxt2 53 33 trial trial NN cord-327516-i25whxt2 53 34 , , , cord-327516-i25whxt2 53 35 as as IN cord-327516-i25whxt2 53 36 has have VBZ cord-327516-i25whxt2 53 37 been be VBN cord-327516-i25whxt2 53 38 achieved achieve VBN cord-327516-i25whxt2 53 39 for for IN cord-327516-i25whxt2 53 40 cancer cancer NN cord-327516-i25whxt2 53 41 , , , cord-327516-i25whxt2 53 42 for for IN cord-327516-i25whxt2 53 43 example example NN cord-327516-i25whxt2 53 44 with with IN cord-327516-i25whxt2 53 45 the the DT cord-327516-i25whxt2 53 46 I I NNP cord-327516-i25whxt2 53 47 - - HYPH cord-327516-i25whxt2 53 48 SPY2 SPY2 NNP cord-327516-i25whxt2 53 49 platform platform NN cord-327516-i25whxt2 53 50 trial trial NN cord-327516-i25whxt2 53 51 21 21 CD cord-327516-i25whxt2 53 52 . . . cord-327516-i25whxt2 54 1 However however RB cord-327516-i25whxt2 54 2 , , , cord-327516-i25whxt2 54 3 at at IN cord-327516-i25whxt2 54 4 this this DT cord-327516-i25whxt2 54 5 time time NN cord-327516-i25whxt2 54 6 , , , cord-327516-i25whxt2 54 7 interventions intervention NNS cord-327516-i25whxt2 54 8 other other JJ cord-327516-i25whxt2 54 9 than than IN cord-327516-i25whxt2 54 10 antivirals antiviral NNS cord-327516-i25whxt2 54 11 can can MD cord-327516-i25whxt2 54 12 probably probably RB cord-327516-i25whxt2 54 13 offer offer VB cord-327516-i25whxt2 54 14 more more JJR cord-327516-i25whxt2 54 15 health health NN cord-327516-i25whxt2 54 16 benefit benefit NN cord-327516-i25whxt2 54 17 globally globally RB cord-327516-i25whxt2 54 18 . . . cord-327516-i25whxt2 55 1 The the DT cord-327516-i25whxt2 55 2 two two CD cord-327516-i25whxt2 55 3 simple simple JJ cord-327516-i25whxt2 55 4 interventions intervention NNS cord-327516-i25whxt2 55 5 that that WDT cord-327516-i25whxt2 55 6 can can MD cord-327516-i25whxt2 55 7 save save VB cord-327516-i25whxt2 55 8 lives life NNS cord-327516-i25whxt2 55 9 are be VBP cord-327516-i25whxt2 55 10 antibiotics antibiotic NNS cord-327516-i25whxt2 55 11 and and CC cord-327516-i25whxt2 55 12 oxygen oxygen NN cord-327516-i25whxt2 55 13 . . . cord-327516-i25whxt2 56 1 Secondary secondary JJ cord-327516-i25whxt2 56 2 bacterial bacterial JJ cord-327516-i25whxt2 56 3 infections infection NNS cord-327516-i25whxt2 56 4 , , , cord-327516-i25whxt2 56 5 largely largely RB cord-327516-i25whxt2 56 6 due due JJ cord-327516-i25whxt2 56 7 to to IN cord-327516-i25whxt2 56 8 Streptococcus streptococcus NN cord-327516-i25whxt2 56 9 pneumoniae pneumoniae NN cord-327516-i25whxt2 56 10 , , , cord-327516-i25whxt2 56 11 are be VBP cord-327516-i25whxt2 56 12 thought think VBN cord-327516-i25whxt2 56 13 to to TO cord-327516-i25whxt2 56 14 have have VB cord-327516-i25whxt2 56 15 made make VBN cord-327516-i25whxt2 56 16 a a DT cord-327516-i25whxt2 56 17 substantial substantial JJ cord-327516-i25whxt2 56 18 contribution contribution NN cord-327516-i25whxt2 56 19 to to IN cord-327516-i25whxt2 56 20 influenzaassociated influenzaassociated JJ cord-327516-i25whxt2 56 21 pneumonia pneumonia NN cord-327516-i25whxt2 56 22 and and CC cord-327516-i25whxt2 56 23 death death NN cord-327516-i25whxt2 56 24 in in IN cord-327516-i25whxt2 56 25 1918 1918 CD cord-327516-i25whxt2 57 1 ( ( -LRB- cord-327516-i25whxt2 57 2 ref ref NN cord-327516-i25whxt2 57 3 . . . cord-327516-i25whxt2 57 4 22 22 CD cord-327516-i25whxt2 57 5 ) ) -RRB- cord-327516-i25whxt2 57 6 . . . cord-327516-i25whxt2 58 1 Despite despite IN cord-327516-i25whxt2 58 2 the the DT cord-327516-i25whxt2 58 3 widespread widespread JJ cord-327516-i25whxt2 58 4 availability availability NN cord-327516-i25whxt2 58 5 of of IN cord-327516-i25whxt2 58 6 antibiotics antibiotic NNS cord-327516-i25whxt2 58 7 , , , cord-327516-i25whxt2 58 8 only only RB cord-327516-i25whxt2 58 9 around around IN cord-327516-i25whxt2 58 10 half half NN cord-327516-i25whxt2 58 11 of of IN cord-327516-i25whxt2 58 12 children child NNS cord-327516-i25whxt2 58 13 with with IN cord-327516-i25whxt2 58 14 pneumonia pneumonia NN cord-327516-i25whxt2 58 15 in in IN cord-327516-i25whxt2 58 16 LMICs lmic NNS cord-327516-i25whxt2 58 17 receive receive VBP cord-327516-i25whxt2 58 18 care care NN cord-327516-i25whxt2 58 19 from from IN cord-327516-i25whxt2 58 20 a a DT cord-327516-i25whxt2 58 21 healthcare healthcare NN cord-327516-i25whxt2 58 22 provider provider NN cord-327516-i25whxt2 58 23 who who WP cord-327516-i25whxt2 58 24 can can MD cord-327516-i25whxt2 58 25 give give VB cord-327516-i25whxt2 58 26 appropriate appropriate JJ cord-327516-i25whxt2 58 27 antibiotics antibiotic NNS cord-327516-i25whxt2 58 28 23 23 CD cord-327516-i25whxt2 58 29 . . . cord-327516-i25whxt2 59 1 Although although IN cord-327516-i25whxt2 59 2 oxygen oxygen NN cord-327516-i25whxt2 59 3 therapy therapy NN cord-327516-i25whxt2 59 4 is be VBZ cord-327516-i25whxt2 59 5 considered consider VBN cord-327516-i25whxt2 59 6 an an DT cord-327516-i25whxt2 59 7 essential essential JJ cord-327516-i25whxt2 59 8 medicine medicine NN cord-327516-i25whxt2 59 9 , , , cord-327516-i25whxt2 59 10 reliable reliable JJ cord-327516-i25whxt2 59 11 access access NN cord-327516-i25whxt2 59 12 to to IN cord-327516-i25whxt2 59 13 oxygen oxygen NN cord-327516-i25whxt2 59 14 is be VBZ cord-327516-i25whxt2 59 15 absent absent JJ cord-327516-i25whxt2 59 16 in in IN cord-327516-i25whxt2 59 17 much much JJ cord-327516-i25whxt2 59 18 of of IN cord-327516-i25whxt2 59 19 the the DT cord-327516-i25whxt2 59 20 world world NN cord-327516-i25whxt2 59 21 due due JJ cord-327516-i25whxt2 59 22 to to IN cord-327516-i25whxt2 59 23 technical technical JJ cord-327516-i25whxt2 59 24 and and CC cord-327516-i25whxt2 59 25 cost cost VB cord-327516-i25whxt2 59 26 challenges challenge NNS cord-327516-i25whxt2 59 27 24 24 CD cord-327516-i25whxt2 59 28 . . . cord-327516-i25whxt2 60 1 The the DT cord-327516-i25whxt2 60 2 other other JJ cord-327516-i25whxt2 60 3 intervention intervention NN cord-327516-i25whxt2 60 4 likely likely JJ cord-327516-i25whxt2 60 5 to to TO cord-327516-i25whxt2 60 6 have have VB cord-327516-i25whxt2 60 7 a a DT cord-327516-i25whxt2 60 8 major major JJ cord-327516-i25whxt2 60 9 impact impact NN cord-327516-i25whxt2 60 10 is be VBZ cord-327516-i25whxt2 60 11 pneumococcal pneumococcal JJ cord-327516-i25whxt2 60 12 conjugate conjugate JJ cord-327516-i25whxt2 60 13 vaccines vaccine NNS cord-327516-i25whxt2 60 14 ( ( -LRB- cord-327516-i25whxt2 60 15 PCVs pcv NNS cord-327516-i25whxt2 60 16 ) ) -RRB- cord-327516-i25whxt2 60 17 . . . cord-327516-i25whxt2 61 1 These these DT cord-327516-i25whxt2 61 2 vaccines vaccine NNS cord-327516-i25whxt2 61 3 have have VBP cord-327516-i25whxt2 61 4 been be VBN cord-327516-i25whxt2 61 5 shown show VBN cord-327516-i25whxt2 61 6 to to TO cord-327516-i25whxt2 61 7 reduce reduce VB cord-327516-i25whxt2 61 8 the the DT cord-327516-i25whxt2 61 9 risk risk NN cord-327516-i25whxt2 61 10 of of IN cord-327516-i25whxt2 61 11 influenza influenza NN cord-327516-i25whxt2 61 12 - - HYPH cord-327516-i25whxt2 61 13 associated associate VBN cord-327516-i25whxt2 61 14 pneumococcal pneumococcal JJ cord-327516-i25whxt2 61 15 disease disease NN cord-327516-i25whxt2 61 16 25 25 CD cord-327516-i25whxt2 61 17 , , , cord-327516-i25whxt2 61 18 and and CC cord-327516-i25whxt2 61 19 an an DT cord-327516-i25whxt2 61 20 analysis analysis NN cord-327516-i25whxt2 61 21 in in IN cord-327516-i25whxt2 61 22 China China NNP cord-327516-i25whxt2 61 23 suggests suggest VBZ cord-327516-i25whxt2 61 24 that that IN cord-327516-i25whxt2 61 25 routine routine JJ cord-327516-i25whxt2 61 26 PCV PCV NNP cord-327516-i25whxt2 61 27 immunization immunization NN cord-327516-i25whxt2 61 28 prior prior RB cord-327516-i25whxt2 61 29 to to IN cord-327516-i25whxt2 61 30 a a DT cord-327516-i25whxt2 61 31 pandemic pandemic NN cord-327516-i25whxt2 61 32 would would MD cord-327516-i25whxt2 61 33 have have VB cord-327516-i25whxt2 61 34 a a DT cord-327516-i25whxt2 61 35 major major JJ cord-327516-i25whxt2 61 36 impact impact NN cord-327516-i25whxt2 61 37 on on IN cord-327516-i25whxt2 61 38 mortality mortality NN cord-327516-i25whxt2 61 39 and and CC cord-327516-i25whxt2 61 40 would would MD cord-327516-i25whxt2 61 41 be be VB cord-327516-i25whxt2 61 42 cost cost VBN cord-327516-i25whxt2 61 43 saving save VBG cord-327516-i25whxt2 61 44 26 26 CD cord-327516-i25whxt2 61 45 . . . cord-327516-i25whxt2 62 1 Globally globally RB cord-327516-i25whxt2 62 2 , , , cord-327516-i25whxt2 62 3 only only RB cord-327516-i25whxt2 62 4 37 37 CD cord-327516-i25whxt2 62 5 % % NN cord-327516-i25whxt2 62 6 of of IN cord-327516-i25whxt2 62 7 children child NNS cord-327516-i25whxt2 62 8 received receive VBD cord-327516-i25whxt2 62 9 three three CD cord-327516-i25whxt2 62 10 doses dose NNS cord-327516-i25whxt2 62 11 of of IN cord-327516-i25whxt2 62 12 PCV PCV NNP cord-327516-i25whxt2 62 13 in in IN cord-327516-i25whxt2 62 14 2015 2015 CD cord-327516-i25whxt2 62 15 , , , cord-327516-i25whxt2 62 16 although although IN cord-327516-i25whxt2 62 17 coverage coverage NN cord-327516-i25whxt2 62 18 is be VBZ cord-327516-i25whxt2 62 19 actually actually RB cord-327516-i25whxt2 62 20 higher high JJR cord-327516-i25whxt2 62 21 in in IN cord-327516-i25whxt2 62 22 low low JJ cord-327516-i25whxt2 62 23 - - HYPH cord-327516-i25whxt2 62 24 income income NN cord-327516-i25whxt2 62 25 than than IN cord-327516-i25whxt2 62 26 highincome highincome NN cord-327516-i25whxt2 62 27 countries country NNS cord-327516-i25whxt2 62 28 due due JJ cord-327516-i25whxt2 62 29 to to TO cord-327516-i25whxt2 62 30 support support NN cord-327516-i25whxt2 62 31 from from IN cord-327516-i25whxt2 62 32 agencies agency NNS cord-327516-i25whxt2 62 33 such such JJ cord-327516-i25whxt2 62 34 as as IN cord-327516-i25whxt2 62 35 Gavi Gavi NNP cord-327516-i25whxt2 62 36 , , , cord-327516-i25whxt2 62 37 the the DT cord-327516-i25whxt2 62 38 Vaccine Vaccine NNP cord-327516-i25whxt2 62 39 Alliance Alliance NNP cord-327516-i25whxt2 62 40 27 27 CD cord-327516-i25whxt2 62 41 . . . cord-327516-i25whxt2 63 1 Effective effective JJ cord-327516-i25whxt2 63 2 , , , cord-327516-i25whxt2 63 3 safe safe JJ cord-327516-i25whxt2 63 4 and and CC cord-327516-i25whxt2 63 5 affordable affordable JJ cord-327516-i25whxt2 63 6 interventions intervention NNS cord-327516-i25whxt2 63 7 , , , cord-327516-i25whxt2 63 8 such such JJ cord-327516-i25whxt2 63 9 as as IN cord-327516-i25whxt2 63 10 antibiotics antibiotic NNS cord-327516-i25whxt2 63 11 , , , cord-327516-i25whxt2 63 12 oxygen oxygen NN cord-327516-i25whxt2 63 13 and and CC cord-327516-i25whxt2 63 14 PCVs pcv NNS cord-327516-i25whxt2 63 15 , , , cord-327516-i25whxt2 63 16 will will MD cord-327516-i25whxt2 63 17 save save VB cord-327516-i25whxt2 63 18 lives life NNS cord-327516-i25whxt2 63 19 during during IN cord-327516-i25whxt2 63 20 an an DT cord-327516-i25whxt2 63 21 influenza influenza NN cord-327516-i25whxt2 63 22 pandemic pandemic NN cord-327516-i25whxt2 63 23 and and CC cord-327516-i25whxt2 63 24 are be VBP cord-327516-i25whxt2 63 25 available available JJ cord-327516-i25whxt2 63 26 now now RB cord-327516-i25whxt2 63 27 . . . cord-327516-i25whxt2 64 1 Such such JJ cord-327516-i25whxt2 64 2 interventions intervention NNS cord-327516-i25whxt2 64 3 should should MD cord-327516-i25whxt2 64 4 be be VB cord-327516-i25whxt2 64 5 made make VBN cord-327516-i25whxt2 64 6 available available JJ cord-327516-i25whxt2 64 7 to to IN cord-327516-i25whxt2 64 8 all all DT cord-327516-i25whxt2 64 9 . . . cord-327516-i25whxt2 65 1 Whilst whilst IN cord-327516-i25whxt2 65 2 current current JJ cord-327516-i25whxt2 65 3 influenza influenza NN cord-327516-i25whxt2 65 4 vaccines vaccine NNS cord-327516-i25whxt2 65 5 meet meet VBP cord-327516-i25whxt2 65 6 an an DT cord-327516-i25whxt2 65 7 important important JJ cord-327516-i25whxt2 65 8 need need NN cord-327516-i25whxt2 65 9 and and CC cord-327516-i25whxt2 65 10 their -PRON- PRP$ cord-327516-i25whxt2 65 11 wider wide JJR cord-327516-i25whxt2 65 12 use use NN cord-327516-i25whxt2 65 13 should should MD cord-327516-i25whxt2 65 14 be be VB cord-327516-i25whxt2 65 15 promoted promote VBN cord-327516-i25whxt2 65 16 , , , cord-327516-i25whxt2 65 17 traditional traditional JJ cord-327516-i25whxt2 65 18 influenza influenza NN cord-327516-i25whxt2 65 19 immunization immunization NN cord-327516-i25whxt2 65 20 approaches approach NNS cord-327516-i25whxt2 65 21 and and CC cord-327516-i25whxt2 65 22 the the DT cord-327516-i25whxt2 65 23 predominant predominant JJ cord-327516-i25whxt2 65 24 egg egg NN cord-327516-i25whxt2 65 25 - - HYPH cord-327516-i25whxt2 65 26 based base VBN cord-327516-i25whxt2 65 27 production production NN cord-327516-i25whxt2 65 28 methods method NNS cord-327516-i25whxt2 65 29 seriously seriously RB cord-327516-i25whxt2 65 30 limit limit VBP cord-327516-i25whxt2 65 31 their -PRON- PRP$ cord-327516-i25whxt2 65 32 value value NN cord-327516-i25whxt2 65 33 as as IN cord-327516-i25whxt2 65 34 a a DT cord-327516-i25whxt2 65 35 tool tool NN cord-327516-i25whxt2 65 36 in in IN cord-327516-i25whxt2 65 37 pandemic pandemic JJ cord-327516-i25whxt2 65 38 preparedness preparedness NN cord-327516-i25whxt2 65 39 . . . cord-327516-i25whxt2 66 1 There there EX cord-327516-i25whxt2 66 2 has have VBZ cord-327516-i25whxt2 66 3 certainly certainly RB cord-327516-i25whxt2 66 4 been be VBN cord-327516-i25whxt2 66 5 progress progress NN cord-327516-i25whxt2 66 6 in in IN cord-327516-i25whxt2 66 7 the the DT cord-327516-i25whxt2 66 8 speed speed NN cord-327516-i25whxt2 66 9 of of IN cord-327516-i25whxt2 66 10 development development NN cord-327516-i25whxt2 66 11 and and CC cord-327516-i25whxt2 66 12 breadth breadth NN cord-327516-i25whxt2 66 13 of of IN cord-327516-i25whxt2 66 14 candidate candidate NN cord-327516-i25whxt2 66 15 vaccine vaccine NN cord-327516-i25whxt2 66 16 viruses virus NNS cord-327516-i25whxt2 66 17 , , , cord-327516-i25whxt2 66 18 and and CC cord-327516-i25whxt2 66 19 in in IN cord-327516-i25whxt2 66 20 the the DT cord-327516-i25whxt2 66 21 diversification diversification NN cord-327516-i25whxt2 66 22 and and CC cord-327516-i25whxt2 66 23 expansion expansion NN cord-327516-i25whxt2 66 24 of of IN cord-327516-i25whxt2 66 25 production production NN cord-327516-i25whxt2 66 26 capacity capacity NN cord-327516-i25whxt2 66 27 -global -global JJ cord-327516-i25whxt2 66 28 pandemic pandemic NN cord-327516-i25whxt2 66 29 influenza influenza NN cord-327516-i25whxt2 66 30 vaccine vaccine NN cord-327516-i25whxt2 66 31 production production NN cord-327516-i25whxt2 66 32 capacity capacity NN cord-327516-i25whxt2 66 33 is be VBZ cord-327516-i25whxt2 66 34 at at IN cord-327516-i25whxt2 66 35 its -PRON- PRP$ cord-327516-i25whxt2 66 36 highest high JJS cord-327516-i25whxt2 66 37 level level NN cord-327516-i25whxt2 66 38 ever ever RB cord-327516-i25whxt2 66 39 , , , cord-327516-i25whxt2 66 40 and and CC cord-327516-i25whxt2 66 41 may may MD cord-327516-i25whxt2 66 42 be be VB cord-327516-i25whxt2 66 43 sufficient sufficient JJ cord-327516-i25whxt2 66 44 to to TO cord-327516-i25whxt2 66 45 immunize immunize VB cord-327516-i25whxt2 66 46 43 43 CD cord-327516-i25whxt2 66 47 % % NN cord-327516-i25whxt2 66 48 of of IN cord-327516-i25whxt2 66 49 the the DT cord-327516-i25whxt2 66 50 current current JJ cord-327516-i25whxt2 66 51 global global JJ cord-327516-i25whxt2 66 52 population population NN cord-327516-i25whxt2 66 53 with with IN cord-327516-i25whxt2 66 54 two two CD cord-327516-i25whxt2 66 55 doses dose NNS cord-327516-i25whxt2 66 56 , , , cord-327516-i25whxt2 66 57 or or CC cord-327516-i25whxt2 66 58 86 86 CD cord-327516-i25whxt2 66 59 % % NN cord-327516-i25whxt2 66 60 with with IN cord-327516-i25whxt2 66 61 one one CD cord-327516-i25whxt2 66 62 dose dose NN cord-327516-i25whxt2 66 63 28 28 CD cord-327516-i25whxt2 66 64 . . . cord-327516-i25whxt2 67 1 Nevertheless nevertheless RB cord-327516-i25whxt2 67 2 , , , cord-327516-i25whxt2 67 3 the the DT cord-327516-i25whxt2 67 4 time time NN cord-327516-i25whxt2 67 5 frame frame NN cord-327516-i25whxt2 67 6 to to TO cord-327516-i25whxt2 67 7 produce produce VB cord-327516-i25whxt2 67 8 and and CC cord-327516-i25whxt2 67 9 evaluate evaluate VB cord-327516-i25whxt2 67 10 new new JJ cord-327516-i25whxt2 67 11 vaccines vaccine NNS cord-327516-i25whxt2 67 12 against against IN cord-327516-i25whxt2 67 13 novel novel JJ cord-327516-i25whxt2 67 14 antigenic antigenic JJ cord-327516-i25whxt2 67 15 variants variant NNS cord-327516-i25whxt2 67 16 and and CC cord-327516-i25whxt2 67 17 to to TO cord-327516-i25whxt2 67 18 switch switch VB cord-327516-i25whxt2 67 19 vaccine vaccine NN cord-327516-i25whxt2 67 20 production production NN cord-327516-i25whxt2 67 21 is be VBZ cord-327516-i25whxt2 67 22 still still RB cord-327516-i25whxt2 67 23 too too RB cord-327516-i25whxt2 67 24 slow slow JJ cord-327516-i25whxt2 67 25 to to TO cord-327516-i25whxt2 67 26 have have VB cord-327516-i25whxt2 67 27 a a DT cord-327516-i25whxt2 67 28 substantial substantial JJ cord-327516-i25whxt2 67 29 impact impact NN cord-327516-i25whxt2 67 30 on on IN cord-327516-i25whxt2 67 31 the the DT cord-327516-i25whxt2 67 32 first first JJ cord-327516-i25whxt2 67 33 wave wave NN cord-327516-i25whxt2 67 34 of of IN cord-327516-i25whxt2 67 35 a a DT cord-327516-i25whxt2 67 36 pandemic pandemic NN cord-327516-i25whxt2 67 37 . . . cord-327516-i25whxt2 68 1 Only only JJ cord-327516-i25whxt2 68 2 time time NN cord-327516-i25whxt2 68 3 will will MD cord-327516-i25whxt2 68 4 tell tell VB cord-327516-i25whxt2 68 5 if if IN cord-327516-i25whxt2 68 6 the the DT cord-327516-i25whxt2 68 7 notional notional JJ cord-327516-i25whxt2 68 8 pandemic pandemic NN cord-327516-i25whxt2 68 9 vaccine vaccine NN cord-327516-i25whxt2 68 10 production production NN cord-327516-i25whxt2 68 11 capacity capacity NN cord-327516-i25whxt2 68 12 will will MD cord-327516-i25whxt2 68 13 ever ever RB cord-327516-i25whxt2 68 14 be be VB cord-327516-i25whxt2 68 15 realized realize VBN cord-327516-i25whxt2 68 16 , , , cord-327516-i25whxt2 68 17 and and CC cord-327516-i25whxt2 68 18 a a DT cord-327516-i25whxt2 68 19 pandemic pandemic JJ cord-327516-i25whxt2 68 20 vaccine vaccine NN cord-327516-i25whxt2 68 21 will will MD cord-327516-i25whxt2 68 22 find find VB cord-327516-i25whxt2 68 23 its -PRON- PRP$ cord-327516-i25whxt2 68 24 way way NN cord-327516-i25whxt2 68 25 into into IN cord-327516-i25whxt2 68 26 people people NNS cord-327516-i25whxt2 68 27 's 's POS cord-327516-i25whxt2 68 28 arms arm NNS cord-327516-i25whxt2 68 29 in in IN cord-327516-i25whxt2 68 30 time time NN cord-327516-i25whxt2 68 31 . . . cord-327516-i25whxt2 69 1 Substantial substantial JJ cord-327516-i25whxt2 69 2 efforts effort NNS cord-327516-i25whxt2 69 3 are be VBP cord-327516-i25whxt2 69 4 ongoing ongoing JJ cord-327516-i25whxt2 69 5 to to TO cord-327516-i25whxt2 69 6 optimize optimize VB cord-327516-i25whxt2 69 7 the the DT cord-327516-i25whxt2 69 8 use use NN cord-327516-i25whxt2 69 9 of of IN cord-327516-i25whxt2 69 10 existing exist VBG cord-327516-i25whxt2 69 11 vaccine vaccine NN cord-327516-i25whxt2 69 12 technologies technology NNS cord-327516-i25whxt2 69 13 and and CC cord-327516-i25whxt2 69 14 to to TO cord-327516-i25whxt2 69 15 develop develop VB cord-327516-i25whxt2 69 16 novel novel JJ cord-327516-i25whxt2 69 17 approaches approach NNS cord-327516-i25whxt2 69 18 , , , cord-327516-i25whxt2 69 19 including include VBG cord-327516-i25whxt2 69 20 , , , cord-327516-i25whxt2 69 21 most most RBS cord-327516-i25whxt2 69 22 importantly importantly RB cord-327516-i25whxt2 69 23 , , , cord-327516-i25whxt2 69 24 work work VBP cord-327516-i25whxt2 69 25 to to TO cord-327516-i25whxt2 69 26 realize realize VB cord-327516-i25whxt2 69 27 the the DT cord-327516-i25whxt2 69 28 aspiration aspiration NN cord-327516-i25whxt2 69 29 of of IN cord-327516-i25whxt2 69 30 a a DT cord-327516-i25whxt2 69 31 broadly broadly RB cord-327516-i25whxt2 69 32 protective protective JJ cord-327516-i25whxt2 69 33 , , , cord-327516-i25whxt2 69 34 universal universal JJ cord-327516-i25whxt2 69 35 influenza influenza NN cord-327516-i25whxt2 69 36 vaccine vaccine NN cord-327516-i25whxt2 69 37 . . . cord-327516-i25whxt2 70 1 These these DT cord-327516-i25whxt2 70 2 efforts effort NNS cord-327516-i25whxt2 70 3 are be VBP cord-327516-i25whxt2 70 4 of of IN cord-327516-i25whxt2 70 5 major major JJ cord-327516-i25whxt2 70 6 global global JJ cord-327516-i25whxt2 70 7 importance importance NN cord-327516-i25whxt2 70 8 and and CC cord-327516-i25whxt2 70 9 must must MD cord-327516-i25whxt2 70 10 continue continue VB cord-327516-i25whxt2 70 11 to to TO cord-327516-i25whxt2 70 12 be be VB cord-327516-i25whxt2 70 13 supported support VBN cord-327516-i25whxt2 70 14 . . . cord-327516-i25whxt2 71 1 If if IN cord-327516-i25whxt2 71 2 we -PRON- PRP cord-327516-i25whxt2 71 3 do do VBP cord-327516-i25whxt2 71 4 not not RB cord-327516-i25whxt2 71 5 keep keep VB cord-327516-i25whxt2 71 6 our -PRON- PRP$ cord-327516-i25whxt2 71 7 eye eye NN cord-327516-i25whxt2 71 8 on on IN cord-327516-i25whxt2 71 9 the the DT cord-327516-i25whxt2 71 10 ball ball NN cord-327516-i25whxt2 71 11 and and CC cord-327516-i25whxt2 71 12 continue continue VB cord-327516-i25whxt2 71 13 to to TO cord-327516-i25whxt2 71 14 aggressively aggressively RB cord-327516-i25whxt2 71 15 pursue pursue VB cord-327516-i25whxt2 71 16 improvements improvement NNS cord-327516-i25whxt2 71 17 in in IN cord-327516-i25whxt2 71 18 pandemic pandemic NN cord-327516-i25whxt2 71 19 influenza influenza NN cord-327516-i25whxt2 71 20 comment comment NN cord-327516-i25whxt2 71 21 preparedness preparedness NN cord-327516-i25whxt2 71 22 across across IN cord-327516-i25whxt2 71 23 the the DT cord-327516-i25whxt2 71 24 whole whole JJ cord-327516-i25whxt2 71 25 range range NN cord-327516-i25whxt2 71 26 of of IN cord-327516-i25whxt2 71 27 disciplines discipline NNS cord-327516-i25whxt2 71 28 , , , cord-327516-i25whxt2 71 29 including include VBG cord-327516-i25whxt2 71 30 basic basic JJ cord-327516-i25whxt2 71 31 science science NN cord-327516-i25whxt2 71 32 , , , cord-327516-i25whxt2 71 33 vaccinology vaccinology NN cord-327516-i25whxt2 71 34 , , , cord-327516-i25whxt2 71 35 clinical clinical JJ cord-327516-i25whxt2 71 36 evaluation evaluation NN cord-327516-i25whxt2 71 37 and and CC cord-327516-i25whxt2 71 38 therapeutics therapeutic NNS cord-327516-i25whxt2 71 39 , , , cord-327516-i25whxt2 71 40 public public JJ cord-327516-i25whxt2 71 41 health health NN cord-327516-i25whxt2 71 42 and and CC cord-327516-i25whxt2 71 43 health health NN cord-327516-i25whxt2 71 44 service service NN cord-327516-i25whxt2 71 45 delivery delivery NN cord-327516-i25whxt2 71 46 , , , cord-327516-i25whxt2 71 47 we -PRON- PRP cord-327516-i25whxt2 71 48 will will MD cord-327516-i25whxt2 71 49 be be VB cord-327516-i25whxt2 71 50 culpable culpable JJ cord-327516-i25whxt2 71 51 of of IN cord-327516-i25whxt2 71 52 neglecting neglect VBG cord-327516-i25whxt2 71 53 the the DT cord-327516-i25whxt2 71 54 obvious obvious JJ cord-327516-i25whxt2 71 55 risks risk NNS cord-327516-i25whxt2 71 56 in in IN cord-327516-i25whxt2 71 57 favour favour NN cord-327516-i25whxt2 71 58 of of IN cord-327516-i25whxt2 71 59 the the DT cord-327516-i25whxt2 71 60 more more RBR cord-327516-i25whxt2 71 61 exotic exotic JJ cord-327516-i25whxt2 71 62 and and CC cord-327516-i25whxt2 71 63 dramatic dramatic JJ cord-327516-i25whxt2 71 64 . . . cord-327516-i25whxt2 72 1 Whilst whilst IN cord-327516-i25whxt2 72 2 the the DT cord-327516-i25whxt2 72 3 recently recently RB cord-327516-i25whxt2 72 4 updated update VBN cord-327516-i25whxt2 72 5 World World NNP cord-327516-i25whxt2 72 6 Health Health NNP cord-327516-i25whxt2 72 7 Organization Organization NNP cord-327516-i25whxt2 72 8 public public JJ cord-327516-i25whxt2 72 9 health health NN cord-327516-i25whxt2 72 10 research research NN cord-327516-i25whxt2 72 11 agenda agenda NN cord-327516-i25whxt2 72 12 for for IN cord-327516-i25whxt2 72 13 influenza influenza NN cord-327516-i25whxt2 72 14 has have VBZ cord-327516-i25whxt2 72 15 some some DT cord-327516-i25whxt2 72 16 value value NN cord-327516-i25whxt2 72 17 , , , cord-327516-i25whxt2 72 18 it -PRON- PRP cord-327516-i25whxt2 72 19 does do VBZ cord-327516-i25whxt2 72 20 not not RB cord-327516-i25whxt2 72 21 constitute constitute VB cord-327516-i25whxt2 72 22 a a DT cord-327516-i25whxt2 72 23 strategic strategic JJ cord-327516-i25whxt2 72 24 plan plan NN cord-327516-i25whxt2 72 25 of of IN cord-327516-i25whxt2 72 26 action action NN cord-327516-i25whxt2 72 27 . . . cord-327516-i25whxt2 73 1 As as IN cord-327516-i25whxt2 73 2 we -PRON- PRP cord-327516-i25whxt2 73 3 have have VBP cord-327516-i25whxt2 73 4 seen see VBN cord-327516-i25whxt2 73 5 being be VBG cord-327516-i25whxt2 73 6 recently recently RB cord-327516-i25whxt2 73 7 developed develop VBN cord-327516-i25whxt2 73 8 for for IN cord-327516-i25whxt2 73 9 other other JJ cord-327516-i25whxt2 73 10 high high JJ cord-327516-i25whxt2 73 11 - - HYPH cord-327516-i25whxt2 73 12 threat threat NN cord-327516-i25whxt2 73 13 pathogens pathogen NNS cord-327516-i25whxt2 73 14 , , , cord-327516-i25whxt2 73 15 such such JJ cord-327516-i25whxt2 73 16 as as IN cord-327516-i25whxt2 73 17 the the DT cord-327516-i25whxt2 73 18 viral viral JJ cord-327516-i25whxt2 73 19 haemorrhagic haemorrhagic JJ cord-327516-i25whxt2 73 20 fevers fever NNS cord-327516-i25whxt2 73 21 and and CC cord-327516-i25whxt2 73 22 Middle Middle NNP cord-327516-i25whxt2 73 23 East East NNP cord-327516-i25whxt2 73 24 respiratory respiratory JJ cord-327516-i25whxt2 73 25 syndrome syndrome NN cord-327516-i25whxt2 73 26 coronavirus coronavirus NN cord-327516-i25whxt2 73 27 , , , cord-327516-i25whxt2 73 28 what what WP cord-327516-i25whxt2 73 29 is be VBZ cord-327516-i25whxt2 73 30 needed need VBN cord-327516-i25whxt2 73 31 is be VBZ cord-327516-i25whxt2 73 32 a a DT cord-327516-i25whxt2 73 33 blueprint blueprint NN cord-327516-i25whxt2 73 34 for for IN cord-327516-i25whxt2 73 35 action action NN cord-327516-i25whxt2 73 36 against against IN cord-327516-i25whxt2 73 37 pandemic pandemic NN cord-327516-i25whxt2 73 38 influenza influenza NN cord-327516-i25whxt2 73 39 that that WDT cord-327516-i25whxt2 73 40 is be VBZ cord-327516-i25whxt2 73 41 comprehensive comprehensive JJ cord-327516-i25whxt2 73 42 , , , cord-327516-i25whxt2 73 43 detailed detailed JJ cord-327516-i25whxt2 73 44 , , , cord-327516-i25whxt2 73 45 endorsed endorse VBN cord-327516-i25whxt2 73 46 , , , cord-327516-i25whxt2 73 47 funded fund VBN cord-327516-i25whxt2 73 48 and and CC cord-327516-i25whxt2 73 49 monitored monitor VBN cord-327516-i25whxt2 73 50 . . . cord-327516-i25whxt2 74 1 ❐ ❐ UH cord-327516-i25whxt2 74 2 Peter Peter NNP cord-327516-i25whxt2 74 3 Horby Horby NNP cord-327516-i25whxt2 75 1 1,2 1,2 LS cord-327516-i25whxt2 76 1 Notice notice NN cord-327516-i25whxt2 76 2 announcing announce VBG cord-327516-i25whxt2 76 3 the the DT cord-327516-i25whxt2 76 4 removal removal NN cord-327516-i25whxt2 76 5 of of IN cord-327516-i25whxt2 76 6 the the DT cord-327516-i25whxt2 76 7 funding funding NN cord-327516-i25whxt2 76 8 pause pause NN cord-327516-i25whxt2 76 9 for for IN cord-327516-i25whxt2 76 10 gain gain NN cord-327516-i25whxt2 76 11 - - HYPH cord-327516-i25whxt2 76 12 offunction offunction NN cord-327516-i25whxt2 76 13 research research NN cord-327516-i25whxt2 76 14 projects project NNS cord-327516-i25whxt2 77 1 Vaccine Vaccine NNP cord-327516-i25whxt2 77 2 Trialist Trialist NNP cord-327516-i25whxt2 77 3 Group Group NNP cord-327516-i25whxt2 78 1 The the DT cord-327516-i25whxt2 78 2 author author NN cord-327516-i25whxt2 78 3 declares declare VBZ cord-327516-i25whxt2 78 4 no no DT cord-327516-i25whxt2 78 5 competing compete VBG cord-327516-i25whxt2 78 6 interests interest NNS cord-327516-i25whxt2 78 7 . . .