id author title date pages extension mime words sentences flesch summary cache txt cord-323202-kcy8xoos Burns, Jane C. Temporal Clusters of Kawasaki Disease Cases Share Distinct Phenotypes That Suggest Response to Diverse Triggers 2020-09-22 .txt text/plain 3483 168 52 The observed and synthetic KD clusters were compared with respect to demographic and clinical characteristics and median values for standard laboratory data using univariate analysis and a multivariate, Rotated Empirical Orthogonal Function Analysis (REOFs). CONCLUSIONS: Cases of Kawasaki disease within a cluster were more similar with respect to demographic and clinical features, and levels of inflammation than would be expected by chance. In the univariate analysis, cluster-level averages of demographic and clinical characteristics were compared between the set of 47 true KD clusters and 100 sets of 47 synthetic clusters of equal size created either by randomly shuffling membership of cluster cases (referred to as shuffled clusters) or by randomly creating clusters from non-cluster cases of Kawasaki disease within the same season as the true cluster (referred to as control clusters). (Figure 2 ; available at www.jpeds.com) Striking differences were noted between individual true clusters and synthetic clusters for the following variables: age, ESR, and the presence of enlarged lymph nodes or strawberry tongue. ./cache/cord-323202-kcy8xoos.txt ./txt/cord-323202-kcy8xoos.txt