id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-342372-2g9sq36w	Zhu, Frank H.	The Clinical Diagnosis and Management of Kawasaki Disease: a Review and Update	2016-09-28		.txt	text/plain	5962	315	41	The use of corticosteroids in patients with KD is currently reserved for children who have received ≥2 infusions of IVIG on the basis that effects of steroid therapy on coronary artery abnormalities were uncertain at the time of publication of KD treatment guidelines in 2004. In Japan, the study on the efficacy of IVIG and steroids in patients with severe presentation of KD (RAISE study), a multicenter, prospective, randomized, open-label, blinded-endpoints trial, showed combination treatment with IVIG and prednisolone had significant advantages over IVIG alone in the prevention of coronary artery abnormalities with rapid defervescence of fever and normalization of inflammatory markers [41•] . The earlier initiation of IVIG and corticosteroid therapy with subsequent increased steroid treatment duration was associated with significantly lower rates of coronary artery abnormalities in the RAISE study. Treatment with infliximab in patients with refractory Kawasaki disease was associated with shorter duration of fever and hospitalization when compared to second dose of IVIG in this randomized	./cache/cord-342372-2g9sq36w.txt	./txt/cord-342372-2g9sq36w.txt