id sid tid token lemma pos cord-293714-s6ezxi5r 1 1 key key JJ cord-293714-s6ezxi5r 2 1 : : : cord-293714-s6ezxi5r 2 2 cord-293714-s6ezxi5r cord-293714-s6ezxi5r NN cord-293714-s6ezxi5r 2 3 authors author NNS cord-293714-s6ezxi5r 2 4 : : : cord-293714-s6ezxi5r 2 5 Principi Principi NNP cord-293714-s6ezxi5r 2 6 , , , cord-293714-s6ezxi5r 2 7 Nicola Nicola NNP cord-293714-s6ezxi5r 2 8 ; ; : cord-293714-s6ezxi5r 2 9 Rigante Rigante NNP cord-293714-s6ezxi5r 2 10 , , , cord-293714-s6ezxi5r 2 11 Donato Donato NNP cord-293714-s6ezxi5r 2 12 ; ; : cord-293714-s6ezxi5r 2 13 Esposito Esposito NNP cord-293714-s6ezxi5r 2 14 , , , cord-293714-s6ezxi5r 2 15 Susanna Susanna NNP cord-293714-s6ezxi5r 2 16 title title NN cord-293714-s6ezxi5r 2 17 : : : cord-293714-s6ezxi5r 3 1 The the DT cord-293714-s6ezxi5r 3 2 role role NN cord-293714-s6ezxi5r 3 3 of of IN cord-293714-s6ezxi5r 3 4 infection infection NN cord-293714-s6ezxi5r 3 5 in in IN cord-293714-s6ezxi5r 3 6 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 3 7 syndrome syndrome NN cord-293714-s6ezxi5r 3 8 date date NN cord-293714-s6ezxi5r 3 9 : : : cord-293714-s6ezxi5r 3 10 2013 2013 CD cord-293714-s6ezxi5r 3 11 - - SYM cord-293714-s6ezxi5r 3 12 04 04 CD cord-293714-s6ezxi5r 3 13 - - SYM cord-293714-s6ezxi5r 3 14 18 18 CD cord-293714-s6ezxi5r 3 15 journal journal NN cord-293714-s6ezxi5r 3 16 : : : cord-293714-s6ezxi5r 3 17 J J NNP cord-293714-s6ezxi5r 3 18 Infect infect VB cord-293714-s6ezxi5r 3 19 DOI DOI NNP cord-293714-s6ezxi5r 3 20 : : : cord-293714-s6ezxi5r 4 1 10.1016 10.1016 CD cord-293714-s6ezxi5r 4 2 / / SYM cord-293714-s6ezxi5r 4 3 j.jinf.2013.04.004 j.jinf.2013.04.004 NNP cord-293714-s6ezxi5r 4 4 sha sha XX cord-293714-s6ezxi5r 4 5 : : : cord-293714-s6ezxi5r 5 1 6f3080ceb7c320fe00adf13d1eaf9f7695b7ec87 6f3080ceb7c320fe00adf13d1eaf9f7695b7ec87 CD cord-293714-s6ezxi5r 5 2 doc_id doc_id CD cord-293714-s6ezxi5r 5 3 : : : cord-293714-s6ezxi5r 6 1 293714 293714 CD cord-293714-s6ezxi5r 6 2 cord_uid cord_uid NNS cord-293714-s6ezxi5r 6 3 : : : cord-293714-s6ezxi5r 7 1 s6ezxi5r s6ezxi5r CD cord-293714-s6ezxi5r 7 2 OBJECTIVES objectives NN cord-293714-s6ezxi5r 7 3 : : : cord-293714-s6ezxi5r 8 1 To to TO cord-293714-s6ezxi5r 8 2 analyse analyse VB cord-293714-s6ezxi5r 8 3 the the DT cord-293714-s6ezxi5r 8 4 evidence evidence NN cord-293714-s6ezxi5r 8 5 suggesting suggest VBG cord-293714-s6ezxi5r 8 6 a a DT cord-293714-s6ezxi5r 8 7 possible possible JJ cord-293714-s6ezxi5r 8 8 infectious infectious JJ cord-293714-s6ezxi5r 8 9 origin origin NN cord-293714-s6ezxi5r 8 10 of of IN cord-293714-s6ezxi5r 8 11 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 8 12 syndrome syndrome NN cord-293714-s6ezxi5r 8 13 ( ( -LRB- cord-293714-s6ezxi5r 8 14 KS KS NNP cord-293714-s6ezxi5r 8 15 ) ) -RRB- cord-293714-s6ezxi5r 8 16 . . . cord-293714-s6ezxi5r 9 1 METHODS methods NN cord-293714-s6ezxi5r 9 2 : : : cord-293714-s6ezxi5r 10 1 PubMed PubMed NNP cord-293714-s6ezxi5r 10 2 was be VBD cord-293714-s6ezxi5r 10 3 searched search VBN cord-293714-s6ezxi5r 10 4 for for IN cord-293714-s6ezxi5r 10 5 all all DT cord-293714-s6ezxi5r 10 6 of of IN cord-293714-s6ezxi5r 10 7 the the DT cord-293714-s6ezxi5r 10 8 studies study NNS cord-293714-s6ezxi5r 10 9 published publish VBN cord-293714-s6ezxi5r 10 10 over over IN cord-293714-s6ezxi5r 10 11 the the DT cord-293714-s6ezxi5r 10 12 last last JJ cord-293714-s6ezxi5r 10 13 15 15 CD cord-293714-s6ezxi5r 10 14 years year NNS cord-293714-s6ezxi5r 10 15 using use VBG cord-293714-s6ezxi5r 10 16 the the DT cord-293714-s6ezxi5r 10 17 key key JJ cord-293714-s6ezxi5r 10 18 words word NNS cord-293714-s6ezxi5r 10 19 “ " `` cord-293714-s6ezxi5r 10 20 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 10 21 syndrome syndrome NN cord-293714-s6ezxi5r 10 22 ” " '' cord-293714-s6ezxi5r 10 23 or or CC cord-293714-s6ezxi5r 10 24 “ " `` cord-293714-s6ezxi5r 10 25 mucocutaneous mucocutaneous JJ cord-293714-s6ezxi5r 10 26 lymph lymph NNP cord-293714-s6ezxi5r 10 27 node node NNP cord-293714-s6ezxi5r 10 28 syndrome syndrome NN cord-293714-s6ezxi5r 10 29 ” " '' cord-293714-s6ezxi5r 10 30 and and CC cord-293714-s6ezxi5r 10 31 “ " `` cord-293714-s6ezxi5r 10 32 infectious infectious JJ cord-293714-s6ezxi5r 10 33 disease disease NN cord-293714-s6ezxi5r 10 34 ” " '' cord-293714-s6ezxi5r 10 35 or or CC cord-293714-s6ezxi5r 10 36 “ " `` cord-293714-s6ezxi5r 10 37 genetics genetic NNS cord-293714-s6ezxi5r 10 38 ” " '' cord-293714-s6ezxi5r 10 39 or or CC cord-293714-s6ezxi5r 10 40 “ " `` cord-293714-s6ezxi5r 10 41 vasculitis vasculitis NN cord-293714-s6ezxi5r 10 42 ” " '' cord-293714-s6ezxi5r 10 43 or or CC cord-293714-s6ezxi5r 10 44 “ " `` cord-293714-s6ezxi5r 10 45 pathogenesis pathogenesis NN cord-293714-s6ezxi5r 10 46 ” " '' cord-293714-s6ezxi5r 10 47 . . . cord-293714-s6ezxi5r 11 1 RESULTS result NNS cord-293714-s6ezxi5r 11 2 : : : cord-293714-s6ezxi5r 12 1 Various various JJ cord-293714-s6ezxi5r 12 2 levels level NNS cord-293714-s6ezxi5r 12 3 of of IN cord-293714-s6ezxi5r 12 4 evidence evidence NN cord-293714-s6ezxi5r 12 5 support support VBP cord-293714-s6ezxi5r 12 6 the the DT cord-293714-s6ezxi5r 12 7 hypothesis hypothesis NN cord-293714-s6ezxi5r 12 8 that that IN cord-293714-s6ezxi5r 12 9 KS KS NNP cord-293714-s6ezxi5r 12 10 is be VBZ cord-293714-s6ezxi5r 12 11 a a DT cord-293714-s6ezxi5r 12 12 complex complex JJ cord-293714-s6ezxi5r 12 13 disease disease NN cord-293714-s6ezxi5r 12 14 triggered trigger VBN cord-293714-s6ezxi5r 12 15 by by IN cord-293714-s6ezxi5r 12 16 an an DT cord-293714-s6ezxi5r 12 17 infection infection NN cord-293714-s6ezxi5r 12 18 due due IN cord-293714-s6ezxi5r 12 19 to to IN cord-293714-s6ezxi5r 12 20 one one CD cord-293714-s6ezxi5r 12 21 or or CC cord-293714-s6ezxi5r 12 22 more more JJR cord-293714-s6ezxi5r 12 23 pathogens pathogen NNS cord-293714-s6ezxi5r 12 24 . . . cord-293714-s6ezxi5r 13 1 Viruses virus NNS cord-293714-s6ezxi5r 13 2 or or CC cord-293714-s6ezxi5r 13 3 bacteria bacteria NNS cord-293714-s6ezxi5r 13 4 may may MD cord-293714-s6ezxi5r 13 5 be be VB cord-293714-s6ezxi5r 13 6 the the DT cord-293714-s6ezxi5r 13 7 primum primum NN cord-293714-s6ezxi5r 13 8 movens movens NNP cord-293714-s6ezxi5r 13 9 , , , cord-293714-s6ezxi5r 13 10 although although IN cord-293714-s6ezxi5r 13 11 no no DT cord-293714-s6ezxi5r 13 12 specific specific JJ cord-293714-s6ezxi5r 13 13 infectious infectious JJ cord-293714-s6ezxi5r 13 14 agent agent NN cord-293714-s6ezxi5r 13 15 can can MD cord-293714-s6ezxi5r 13 16 be be VB cord-293714-s6ezxi5r 13 17 considered consider VBN cord-293714-s6ezxi5r 13 18 definitely definitely RB cord-293714-s6ezxi5r 13 19 etiological etiological JJ cord-293714-s6ezxi5r 13 20 . . . cord-293714-s6ezxi5r 14 1 A a DT cord-293714-s6ezxi5r 14 2 number number NN cord-293714-s6ezxi5r 14 3 of of IN cord-293714-s6ezxi5r 14 4 genetic genetic JJ cord-293714-s6ezxi5r 14 5 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 14 6 have have VBP cord-293714-s6ezxi5r 14 7 been be VBN cord-293714-s6ezxi5r 14 8 identified identify VBN cord-293714-s6ezxi5r 14 9 in in IN cord-293714-s6ezxi5r 14 10 subjects subject NNS cord-293714-s6ezxi5r 14 11 with with IN cord-293714-s6ezxi5r 14 12 KS KS NNP cord-293714-s6ezxi5r 14 13 , , , cord-293714-s6ezxi5r 14 14 but but CC cord-293714-s6ezxi5r 14 15 none none NN cord-293714-s6ezxi5r 14 16 of of IN cord-293714-s6ezxi5r 14 17 them -PRON- PRP cord-293714-s6ezxi5r 14 18 can can MD cord-293714-s6ezxi5r 14 19 currently currently RB cord-293714-s6ezxi5r 14 20 be be VB cord-293714-s6ezxi5r 14 21 considered consider VBN cord-293714-s6ezxi5r 14 22 a a DT cord-293714-s6ezxi5r 14 23 real real JJ cord-293714-s6ezxi5r 14 24 marker marker NN cord-293714-s6ezxi5r 14 25 of of IN cord-293714-s6ezxi5r 14 26 susceptibility susceptibility NN cord-293714-s6ezxi5r 14 27 . . . cord-293714-s6ezxi5r 15 1 CONCLUSIONS conclusion NNS cord-293714-s6ezxi5r 15 2 : : : cord-293714-s6ezxi5r 16 1 Various various JJ cord-293714-s6ezxi5r 16 2 data datum NNS cord-293714-s6ezxi5r 16 3 suggest suggest VBP cord-293714-s6ezxi5r 16 4 that that IN cord-293714-s6ezxi5r 16 5 KS KS NNP cord-293714-s6ezxi5r 16 6 is be VBZ cord-293714-s6ezxi5r 16 7 intimately intimately RB cord-293714-s6ezxi5r 16 8 related relate VBN cord-293714-s6ezxi5r 16 9 to to IN cord-293714-s6ezxi5r 16 10 infectious infectious JJ cord-293714-s6ezxi5r 16 11 diseases disease NNS cord-293714-s6ezxi5r 16 12 and and CC cord-293714-s6ezxi5r 16 13 that that IN cord-293714-s6ezxi5r 16 14 its -PRON- PRP$ cord-293714-s6ezxi5r 16 15 clinical clinical JJ cord-293714-s6ezxi5r 16 16 expression expression NN cord-293714-s6ezxi5r 16 17 is be VBZ cord-293714-s6ezxi5r 16 18 influenced influence VBN cord-293714-s6ezxi5r 16 19 by by IN cord-293714-s6ezxi5r 16 20 predisposing predispose VBG cord-293714-s6ezxi5r 16 21 genetic genetic JJ cord-293714-s6ezxi5r 16 22 backgrounds background NNS cord-293714-s6ezxi5r 16 23 , , , cord-293714-s6ezxi5r 16 24 but but CC cord-293714-s6ezxi5r 16 25 our -PRON- PRP$ cord-293714-s6ezxi5r 16 26 knowledge knowledge NN cord-293714-s6ezxi5r 16 27 of of IN cord-293714-s6ezxi5r 16 28 the the DT cord-293714-s6ezxi5r 16 29 infectious infectious JJ cord-293714-s6ezxi5r 16 30 agent(s agent(s NNP cord-293714-s6ezxi5r 16 31 ) ) -RRB- cord-293714-s6ezxi5r 16 32 involved involve VBN cord-293714-s6ezxi5r 16 33 and and CC cord-293714-s6ezxi5r 16 34 the the DT cord-293714-s6ezxi5r 16 35 genetic genetic JJ cord-293714-s6ezxi5r 16 36 characteristics characteristic NNS cord-293714-s6ezxi5r 16 37 of of IN cord-293714-s6ezxi5r 16 38 susceptible susceptible JJ cord-293714-s6ezxi5r 16 39 children child NNS cord-293714-s6ezxi5r 16 40 remains remain VBZ cord-293714-s6ezxi5r 16 41 only only RB cord-293714-s6ezxi5r 16 42 partial partial JJ cord-293714-s6ezxi5r 16 43 . . . cord-293714-s6ezxi5r 17 1 Further further JJ cord-293714-s6ezxi5r 17 2 studies study NNS cord-293714-s6ezxi5r 17 3 are be VBP cord-293714-s6ezxi5r 17 4 needed need VBN cord-293714-s6ezxi5r 17 5 to to TO cord-293714-s6ezxi5r 17 6 address address VB cord-293714-s6ezxi5r 17 7 the the DT cord-293714-s6ezxi5r 17 8 many many JJ cord-293714-s6ezxi5r 17 9 still still RB cord-293714-s6ezxi5r 17 10 open open JJ cord-293714-s6ezxi5r 17 11 questions question NNS cord-293714-s6ezxi5r 17 12 concerning concern VBG cord-293714-s6ezxi5r 17 13 the the DT cord-293714-s6ezxi5r 17 14 disease disease NN cord-293714-s6ezxi5r 17 15 . . . cord-293714-s6ezxi5r 18 1 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 18 2 syndrome syndrome NN cord-293714-s6ezxi5r 18 3 ( ( -LRB- cord-293714-s6ezxi5r 18 4 KS KS NNP cord-293714-s6ezxi5r 18 5 ) ) -RRB- cord-293714-s6ezxi5r 18 6 , , , cord-293714-s6ezxi5r 18 7 originally originally RB cord-293714-s6ezxi5r 18 8 called call VBN cord-293714-s6ezxi5r 18 9 " " `` cord-293714-s6ezxi5r 18 10 mucocutaneous mucocutaneous JJ cord-293714-s6ezxi5r 18 11 lymph lymph NNP cord-293714-s6ezxi5r 18 12 node node NN cord-293714-s6ezxi5r 18 13 syndrome syndrome NN cord-293714-s6ezxi5r 18 14 " " '' cord-293714-s6ezxi5r 18 15 in in IN cord-293714-s6ezxi5r 18 16 1967 1967 CD cord-293714-s6ezxi5r 18 17 , , , cord-293714-s6ezxi5r 18 18 1 1 CD cord-293714-s6ezxi5r 18 19 is be VBZ cord-293714-s6ezxi5r 18 20 an an DT cord-293714-s6ezxi5r 18 21 acute acute JJ cord-293714-s6ezxi5r 18 22 multisystem multisystem JJ cord-293714-s6ezxi5r 18 23 vasculitis vasculitis NN cord-293714-s6ezxi5r 18 24 that that WDT cord-293714-s6ezxi5r 18 25 causes cause VBZ cord-293714-s6ezxi5r 18 26 generalised generalise VBN cord-293714-s6ezxi5r 18 27 inflammatory inflammatory JJ cord-293714-s6ezxi5r 18 28 cell cell NN cord-293714-s6ezxi5r 18 29 tissue tissue NN cord-293714-s6ezxi5r 18 30 injury injury NN cord-293714-s6ezxi5r 18 31 starting start VBG cord-293714-s6ezxi5r 18 32 in in IN cord-293714-s6ezxi5r 18 33 the the DT cord-293714-s6ezxi5r 18 34 vascular vascular JJ cord-293714-s6ezxi5r 18 35 endothelium endothelium NN cord-293714-s6ezxi5r 18 36 and and CC cord-293714-s6ezxi5r 18 37 is be VBZ cord-293714-s6ezxi5r 18 38 mainly mainly RB cord-293714-s6ezxi5r 18 39 encountered encounter VBN cord-293714-s6ezxi5r 18 40 in in IN cord-293714-s6ezxi5r 18 41 children child NNS cord-293714-s6ezxi5r 18 42 aged age VBN cord-293714-s6ezxi5r 18 43 less less JJR cord-293714-s6ezxi5r 18 44 than than IN cord-293714-s6ezxi5r 18 45 five five CD cord-293714-s6ezxi5r 18 46 years year NNS cord-293714-s6ezxi5r 18 47 regardless regardless RB cord-293714-s6ezxi5r 18 48 of of IN cord-293714-s6ezxi5r 18 49 their -PRON- PRP$ cord-293714-s6ezxi5r 18 50 ethnicity ethnicity NN cord-293714-s6ezxi5r 18 51 . . . cord-293714-s6ezxi5r 19 1 1 1 LS cord-293714-s6ezxi5r 20 1 The the DT cord-293714-s6ezxi5r 20 2 injuries injury NNS cord-293714-s6ezxi5r 20 3 are be VBP cord-293714-s6ezxi5r 20 4 particularly particularly RB cord-293714-s6ezxi5r 20 5 severe severe JJ cord-293714-s6ezxi5r 20 6 in in IN cord-293714-s6ezxi5r 20 7 the the DT cord-293714-s6ezxi5r 20 8 coronary coronary JJ cord-293714-s6ezxi5r 20 9 arteries artery NNS cord-293714-s6ezxi5r 20 10 , , , cord-293714-s6ezxi5r 20 11 which which WDT cord-293714-s6ezxi5r 20 12 are be VBP cord-293714-s6ezxi5r 20 13 frequently frequently RB cord-293714-s6ezxi5r 20 14 affected affect VBN cord-293714-s6ezxi5r 20 15 by by IN cord-293714-s6ezxi5r 20 16 dilatations dilatation NNS cord-293714-s6ezxi5r 20 17 , , , cord-293714-s6ezxi5r 20 18 aneurysms aneurysm NNS cord-293714-s6ezxi5r 20 19 or or CC cord-293714-s6ezxi5r 20 20 fistulae fistula NNS cord-293714-s6ezxi5r 20 21 , , , cord-293714-s6ezxi5r 20 22 especially especially RB cord-293714-s6ezxi5r 20 23 in in IN cord-293714-s6ezxi5r 20 24 patients patient NNS cord-293714-s6ezxi5r 20 25 who who WP cord-293714-s6ezxi5r 20 26 do do VBP cord-293714-s6ezxi5r 20 27 not not RB cord-293714-s6ezxi5r 20 28 receive receive VB cord-293714-s6ezxi5r 20 29 prompt prompt JJ cord-293714-s6ezxi5r 20 30 treatment treatment NN cord-293714-s6ezxi5r 20 31 with with IN cord-293714-s6ezxi5r 20 32 intravenous intravenous JJ cord-293714-s6ezxi5r 20 33 immunoglobulins immunoglobulin NNS cord-293714-s6ezxi5r 20 34 and and CC cord-293714-s6ezxi5r 20 35 anti anti JJ cord-293714-s6ezxi5r 20 36 - - JJ cord-293714-s6ezxi5r 20 37 inflammatory inflammatory JJ cord-293714-s6ezxi5r 20 38 doses dose NNS cord-293714-s6ezxi5r 20 39 of of IN cord-293714-s6ezxi5r 20 40 acetylsalicylic acetylsalicylic JJ cord-293714-s6ezxi5r 20 41 acid acid NN cord-293714-s6ezxi5r 20 42 . . . cord-293714-s6ezxi5r 21 1 2 2 LS cord-293714-s6ezxi5r 22 1 Now now RB cord-293714-s6ezxi5r 22 2 that that DT cord-293714-s6ezxi5r 22 3 rheumatic rheumatic JJ cord-293714-s6ezxi5r 22 4 fever fever NN cord-293714-s6ezxi5r 22 5 is be VBZ cord-293714-s6ezxi5r 22 6 largely largely RB cord-293714-s6ezxi5r 22 7 controlled control VBN cord-293714-s6ezxi5r 22 8 , , , cord-293714-s6ezxi5r 22 9 KS KS NNP cord-293714-s6ezxi5r 22 10 has have VBZ cord-293714-s6ezxi5r 22 11 become become VBN cord-293714-s6ezxi5r 22 12 the the DT cord-293714-s6ezxi5r 22 13 leading leading JJ cord-293714-s6ezxi5r 22 14 cause cause NN cord-293714-s6ezxi5r 22 15 of of IN cord-293714-s6ezxi5r 22 16 acquired acquire VBN cord-293714-s6ezxi5r 22 17 heart heart NN cord-293714-s6ezxi5r 22 18 disease disease NN cord-293714-s6ezxi5r 22 19 among among IN cord-293714-s6ezxi5r 22 20 children child NNS cord-293714-s6ezxi5r 22 21 in in IN cord-293714-s6ezxi5r 22 22 industrialised industrialised JJ cord-293714-s6ezxi5r 22 23 countries country NNS cord-293714-s6ezxi5r 22 24 . . . cord-293714-s6ezxi5r 23 1 3 3 LS cord-293714-s6ezxi5r 24 1 As as IN cord-293714-s6ezxi5r 24 2 no no DT cord-293714-s6ezxi5r 24 3 specific specific JJ cord-293714-s6ezxi5r 24 4 diagnostic diagnostic JJ cord-293714-s6ezxi5r 24 5 test test NN cord-293714-s6ezxi5r 24 6 is be VBZ cord-293714-s6ezxi5r 24 7 available available JJ cord-293714-s6ezxi5r 24 8 , , , cord-293714-s6ezxi5r 24 9 KS KS NNP cord-293714-s6ezxi5r 24 10 is be VBZ cord-293714-s6ezxi5r 24 11 identified identify VBN cord-293714-s6ezxi5r 24 12 on on IN cord-293714-s6ezxi5r 24 13 the the DT cord-293714-s6ezxi5r 24 14 basis basis NN cord-293714-s6ezxi5r 24 15 of of IN cord-293714-s6ezxi5r 24 16 a a DT cord-293714-s6ezxi5r 24 17 constellation constellation NN cord-293714-s6ezxi5r 24 18 of of IN cord-293714-s6ezxi5r 24 19 non non JJ cord-293714-s6ezxi5r 24 20 - - JJ cord-293714-s6ezxi5r 24 21 specific specific JJ cord-293714-s6ezxi5r 24 22 clinical clinical JJ cord-293714-s6ezxi5r 24 23 signs sign NNS cord-293714-s6ezxi5r 24 24 . . . cord-293714-s6ezxi5r 25 1 According accord VBG cord-293714-s6ezxi5r 25 2 to to IN cord-293714-s6ezxi5r 25 3 the the DT cord-293714-s6ezxi5r 25 4 American American NNP cord-293714-s6ezxi5r 25 5 Heart Heart NNP cord-293714-s6ezxi5r 25 6 Association Association NNP cord-293714-s6ezxi5r 25 7 guidelines guideline NNS cord-293714-s6ezxi5r 25 8 , , , cord-293714-s6ezxi5r 25 9 4 4 CD cord-293714-s6ezxi5r 25 10 which which WDT cord-293714-s6ezxi5r 25 11 are be VBP cord-293714-s6ezxi5r 25 12 shared share VBN cord-293714-s6ezxi5r 25 13 by by IN cord-293714-s6ezxi5r 25 14 most most JJS cord-293714-s6ezxi5r 25 15 scientific scientific JJ cord-293714-s6ezxi5r 25 16 communities community NNS cord-293714-s6ezxi5r 25 17 throughout throughout IN cord-293714-s6ezxi5r 25 18 the the DT cord-293714-s6ezxi5r 25 19 world world NN cord-293714-s6ezxi5r 25 20 , , , cord-293714-s6ezxi5r 25 21 a a DT cord-293714-s6ezxi5r 25 22 diagnosis diagnosis NN cord-293714-s6ezxi5r 25 23 requires require VBZ cord-293714-s6ezxi5r 25 24 prolonged prolong VBN cord-293714-s6ezxi5r 25 25 fever fever NN cord-293714-s6ezxi5r 25 26 lasting last VBG cord-293714-s6ezxi5r 25 27 more more JJR cord-293714-s6ezxi5r 25 28 than than IN cord-293714-s6ezxi5r 25 29 five five CD cord-293714-s6ezxi5r 25 30 days day NNS cord-293714-s6ezxi5r 25 31 and and CC cord-293714-s6ezxi5r 25 32 at at RB cord-293714-s6ezxi5r 25 33 least least RBS cord-293714-s6ezxi5r 25 34 four four CD cord-293714-s6ezxi5r 25 35 of of IN cord-293714-s6ezxi5r 25 36 the the DT cord-293714-s6ezxi5r 25 37 following follow VBG cord-293714-s6ezxi5r 25 38 signs sign NNS cord-293714-s6ezxi5r 25 39 : : : cord-293714-s6ezxi5r 25 40 1 1 LS cord-293714-s6ezxi5r 25 41 ) ) -RRB- cord-293714-s6ezxi5r 25 42 diffuse diffuse VB cord-293714-s6ezxi5r 25 43 oral oral JJ cord-293714-s6ezxi5r 25 44 cavity cavity NN cord-293714-s6ezxi5r 25 45 inflammation inflammation NN cord-293714-s6ezxi5r 25 46 ( ( -LRB- cord-293714-s6ezxi5r 25 47 including include VBG cord-293714-s6ezxi5r 25 48 pharyngeal pharyngeal JJ cord-293714-s6ezxi5r 25 49 infection infection NN cord-293714-s6ezxi5r 25 50 ) ) -RRB- cord-293714-s6ezxi5r 25 51 , , , cord-293714-s6ezxi5r 25 52 dry dry JJ cord-293714-s6ezxi5r 25 53 fissured fissure VBN cord-293714-s6ezxi5r 25 54 lips lip NNS cord-293714-s6ezxi5r 25 55 , , , cord-293714-s6ezxi5r 25 56 and and CC cord-293714-s6ezxi5r 25 57 a a DT cord-293714-s6ezxi5r 25 58 strawberry strawberry JJ cord-293714-s6ezxi5r 25 59 tongue tongue NN cord-293714-s6ezxi5r 25 60 ) ) -RRB- cord-293714-s6ezxi5r 25 61 ; ; : cord-293714-s6ezxi5r 25 62 2 2 LS cord-293714-s6ezxi5r 25 63 ) ) -RRB- cord-293714-s6ezxi5r 25 64 bilateral bilateral JJ cord-293714-s6ezxi5r 25 65 non non JJ cord-293714-s6ezxi5r 25 66 - - JJ cord-293714-s6ezxi5r 25 67 purulent purulent JJ cord-293714-s6ezxi5r 25 68 conjunctivitis conjunctivitis NN cord-293714-s6ezxi5r 25 69 ; ; : cord-293714-s6ezxi5r 25 70 3 3 LS cord-293714-s6ezxi5r 25 71 ) ) -RRB- cord-293714-s6ezxi5r 25 72 heterogeneous heterogeneous JJ cord-293714-s6ezxi5r 25 73 skin skin NN cord-293714-s6ezxi5r 25 74 rashes rash NNS cord-293714-s6ezxi5r 25 75 ; ; : cord-293714-s6ezxi5r 25 76 4 4 LS cord-293714-s6ezxi5r 25 77 ) ) -RRB- cord-293714-s6ezxi5r 25 78 angioedema angioedema NN cord-293714-s6ezxi5r 25 79 of of IN cord-293714-s6ezxi5r 25 80 the the DT cord-293714-s6ezxi5r 25 81 extremities extremity NNS cord-293714-s6ezxi5r 25 82 ( ( -LRB- cord-293714-s6ezxi5r 25 83 including include VBG cord-293714-s6ezxi5r 25 84 peripheral peripheral JJ cord-293714-s6ezxi5r 25 85 erythema erythema NN cord-293714-s6ezxi5r 25 86 , , , cord-293714-s6ezxi5r 25 87 oedema oedema NN cord-293714-s6ezxi5r 25 88 , , , cord-293714-s6ezxi5r 25 89 or or CC cord-293714-s6ezxi5r 25 90 induration induration NN cord-293714-s6ezxi5r 25 91 of of IN cord-293714-s6ezxi5r 25 92 the the DT cord-293714-s6ezxi5r 25 93 hands hand NNS cord-293714-s6ezxi5r 25 94 or or CC cord-293714-s6ezxi5r 25 95 feet foot NNS cord-293714-s6ezxi5r 25 96 ) ) -RRB- cord-293714-s6ezxi5r 25 97 ; ; : cord-293714-s6ezxi5r 25 98 and and CC cord-293714-s6ezxi5r 25 99 5 5 LS cord-293714-s6ezxi5r 25 100 ) ) -RRB- cord-293714-s6ezxi5r 25 101 non non JJ cord-293714-s6ezxi5r 25 102 - - JJ cord-293714-s6ezxi5r 25 103 purulent purulent JJ cord-293714-s6ezxi5r 25 104 cervical cervical JJ cord-293714-s6ezxi5r 25 105 lymphadenopathy lymphadenopathy NN cord-293714-s6ezxi5r 25 106 exceeding exceed VBG cord-293714-s6ezxi5r 25 107 ! ! . cord-293714-s6ezxi5r 26 1 1.5 1.5 CD cord-293714-s6ezxi5r 26 2 cm cm NNS cord-293714-s6ezxi5r 26 3 in in IN cord-293714-s6ezxi5r 26 4 diameter diameter NN cord-293714-s6ezxi5r 26 5 . . . cord-293714-s6ezxi5r 27 1 In in IN cord-293714-s6ezxi5r 27 2 what what WP cord-293714-s6ezxi5r 27 3 are be VBP cord-293714-s6ezxi5r 27 4 known know VBN cord-293714-s6ezxi5r 27 5 as as IN cord-293714-s6ezxi5r 27 6 " " `` cord-293714-s6ezxi5r 27 7 incomplete incomplete JJ cord-293714-s6ezxi5r 27 8 " " '' cord-293714-s6ezxi5r 27 9 cases case NNS cord-293714-s6ezxi5r 27 10 , , , cord-293714-s6ezxi5r 27 11 one one CD cord-293714-s6ezxi5r 27 12 or or CC cord-293714-s6ezxi5r 27 13 more more JJR cord-293714-s6ezxi5r 27 14 of of IN cord-293714-s6ezxi5r 27 15 these these DT cord-293714-s6ezxi5r 27 16 clinical clinical JJ cord-293714-s6ezxi5r 27 17 signs sign NNS cord-293714-s6ezxi5r 27 18 may may MD cord-293714-s6ezxi5r 27 19 be be VB cord-293714-s6ezxi5r 27 20 absent absent JJ cord-293714-s6ezxi5r 27 21 but but CC cord-293714-s6ezxi5r 27 22 a a DT cord-293714-s6ezxi5r 27 23 diagnosis diagnosis NN cord-293714-s6ezxi5r 27 24 can can MD cord-293714-s6ezxi5r 27 25 still still RB cord-293714-s6ezxi5r 27 26 be be VB cord-293714-s6ezxi5r 27 27 made make VBN cord-293714-s6ezxi5r 27 28 if if IN cord-293714-s6ezxi5r 27 29 there there EX cord-293714-s6ezxi5r 27 30 is be VBZ cord-293714-s6ezxi5r 27 31 echocardiographic echocardiographic JJ cord-293714-s6ezxi5r 27 32 evidence evidence NN cord-293714-s6ezxi5r 27 33 of of IN cord-293714-s6ezxi5r 27 34 coronary coronary JJ cord-293714-s6ezxi5r 27 35 artery artery NN cord-293714-s6ezxi5r 27 36 abnormalities abnormality NNS cord-293714-s6ezxi5r 27 37 . . . cord-293714-s6ezxi5r 28 1 Furthermore furthermore RB cord-293714-s6ezxi5r 28 2 , , , cord-293714-s6ezxi5r 28 3 a a DT cord-293714-s6ezxi5r 28 4 broad broad JJ cord-293714-s6ezxi5r 28 5 range range NN cord-293714-s6ezxi5r 28 6 of of IN cord-293714-s6ezxi5r 28 7 unusual unusual JJ cord-293714-s6ezxi5r 28 8 clinical clinical JJ cord-293714-s6ezxi5r 28 9 finding finding NN cord-293714-s6ezxi5r 28 10 have have VBP cord-293714-s6ezxi5r 28 11 been be VBN cord-293714-s6ezxi5r 28 12 reported report VBN cord-293714-s6ezxi5r 28 13 as as IN cord-293714-s6ezxi5r 28 14 defining define VBG cord-293714-s6ezxi5r 28 15 the the DT cord-293714-s6ezxi5r 28 16 " " `` cord-293714-s6ezxi5r 28 17 atypical atypical JJ cord-293714-s6ezxi5r 28 18 " " '' cord-293714-s6ezxi5r 28 19 variant variant NN cord-293714-s6ezxi5r 28 20 of of IN cord-293714-s6ezxi5r 28 21 KS KS NNP cord-293714-s6ezxi5r 28 22 , , , cord-293714-s6ezxi5r 28 23 including include VBG cord-293714-s6ezxi5r 28 24 aseptic aseptic JJ cord-293714-s6ezxi5r 28 25 meningitis meningitis NN cord-293714-s6ezxi5r 28 26 , , , cord-293714-s6ezxi5r 28 27 peripheral peripheral JJ cord-293714-s6ezxi5r 28 28 facial facial JJ cord-293714-s6ezxi5r 28 29 nerve nerve NN cord-293714-s6ezxi5r 28 30 palsy palsy NN cord-293714-s6ezxi5r 28 31 , , , cord-293714-s6ezxi5r 28 32 uveitis uveitis NN cord-293714-s6ezxi5r 28 33 , , , cord-293714-s6ezxi5r 28 34 gastrointestinal gastrointestinal JJ cord-293714-s6ezxi5r 28 35 complaints complaint NNS cord-293714-s6ezxi5r 28 36 , , , cord-293714-s6ezxi5r 28 37 acalculous acalculous JJ cord-293714-s6ezxi5r 28 38 gallbladder gallbladder NN cord-293714-s6ezxi5r 28 39 hydrops hydrop NNS cord-293714-s6ezxi5r 28 40 , , , cord-293714-s6ezxi5r 28 41 urethritis urethritis JJ cord-293714-s6ezxi5r 28 42 , , , cord-293714-s6ezxi5r 28 43 testicular testicular JJ cord-293714-s6ezxi5r 28 44 swelling swelling NN cord-293714-s6ezxi5r 28 45 , , , cord-293714-s6ezxi5r 28 46 pulmonary pulmonary JJ cord-293714-s6ezxi5r 28 47 nodules nodule NNS cord-293714-s6ezxi5r 28 48 , , , cord-293714-s6ezxi5r 28 49 liver liver NN cord-293714-s6ezxi5r 28 50 impairment impairment NN cord-293714-s6ezxi5r 28 51 with with IN cord-293714-s6ezxi5r 28 52 jaundice jaundice NN cord-293714-s6ezxi5r 28 53 , , , cord-293714-s6ezxi5r 28 54 and and CC cord-293714-s6ezxi5r 28 55 even even RB cord-293714-s6ezxi5r 28 56 hemophagocytic hemophagocytic JJ cord-293714-s6ezxi5r 28 57 syndrome syndrome NN cord-293714-s6ezxi5r 28 58 . . . cord-293714-s6ezxi5r 29 1 5 5 CD cord-293714-s6ezxi5r 29 2 Laboratory laboratory NN cord-293714-s6ezxi5r 29 3 investigations investigation NNS cord-293714-s6ezxi5r 29 4 ( ( -LRB- cord-293714-s6ezxi5r 29 5 listed list VBN cord-293714-s6ezxi5r 29 6 in in IN cord-293714-s6ezxi5r 29 7 Table Table NNP cord-293714-s6ezxi5r 29 8 1 1 CD cord-293714-s6ezxi5r 29 9 ) ) -RRB- cord-293714-s6ezxi5r 29 10 can can MD cord-293714-s6ezxi5r 29 11 only only RB cord-293714-s6ezxi5r 29 12 support support VB cord-293714-s6ezxi5r 29 13 the the DT cord-293714-s6ezxi5r 29 14 diagnosis diagnosis NN cord-293714-s6ezxi5r 29 15 of of IN cord-293714-s6ezxi5r 29 16 KS KS NNP cord-293714-s6ezxi5r 29 17 , , , cord-293714-s6ezxi5r 29 18 but but CC cord-293714-s6ezxi5r 29 19 they -PRON- PRP cord-293714-s6ezxi5r 29 20 still still RB cord-293714-s6ezxi5r 29 21 need need VBP cord-293714-s6ezxi5r 29 22 to to TO cord-293714-s6ezxi5r 29 23 be be VB cord-293714-s6ezxi5r 29 24 validated validate VBN cord-293714-s6ezxi5r 29 25 before before IN cord-293714-s6ezxi5r 29 26 they -PRON- PRP cord-293714-s6ezxi5r 29 27 can can MD cord-293714-s6ezxi5r 29 28 be be VB cord-293714-s6ezxi5r 29 29 used use VBN cord-293714-s6ezxi5r 29 30 in in IN cord-293714-s6ezxi5r 29 31 everyday everyday JJ cord-293714-s6ezxi5r 29 32 clinical clinical JJ cord-293714-s6ezxi5r 29 33 practice practice NN cord-293714-s6ezxi5r 29 34 . . . cord-293714-s6ezxi5r 30 1 However however RB cord-293714-s6ezxi5r 30 2 , , , cord-293714-s6ezxi5r 30 3 although although IN cord-293714-s6ezxi5r 30 4 the the DT cord-293714-s6ezxi5r 30 5 clinical clinical JJ cord-293714-s6ezxi5r 30 6 features feature NNS cord-293714-s6ezxi5r 30 7 of of IN cord-293714-s6ezxi5r 30 8 KS KS NNP cord-293714-s6ezxi5r 30 9 are be VBP cord-293714-s6ezxi5r 30 10 usually usually RB cord-293714-s6ezxi5r 30 11 recognisable recognisable JJ cord-293714-s6ezxi5r 30 12 , , , cord-293714-s6ezxi5r 30 13 its -PRON- PRP$ cord-293714-s6ezxi5r 30 14 underlying underlying JJ cord-293714-s6ezxi5r 30 15 immune immune JJ cord-293714-s6ezxi5r 30 16 mechanisms mechanism NNS cord-293714-s6ezxi5r 30 17 are be VBP cord-293714-s6ezxi5r 30 18 still still RB cord-293714-s6ezxi5r 30 19 being be VBG cord-293714-s6ezxi5r 30 20 investigated investigate VBN cord-293714-s6ezxi5r 30 21 . . . cord-293714-s6ezxi5r 31 1 Most Most JJS cord-293714-s6ezxi5r 31 2 experts expert NNS cord-293714-s6ezxi5r 31 3 consider consider VBP cord-293714-s6ezxi5r 31 4 it -PRON- PRP cord-293714-s6ezxi5r 31 5 to to TO cord-293714-s6ezxi5r 31 6 be be VB cord-293714-s6ezxi5r 31 7 the the DT cord-293714-s6ezxi5r 31 8 consequence consequence NN cord-293714-s6ezxi5r 31 9 of of IN cord-293714-s6ezxi5r 31 10 an an DT cord-293714-s6ezxi5r 31 11 abnormal abnormal JJ cord-293714-s6ezxi5r 31 12 immunological immunological JJ cord-293714-s6ezxi5r 31 13 response response NN cord-293714-s6ezxi5r 31 14 evoked evoke VBN cord-293714-s6ezxi5r 31 15 by by IN cord-293714-s6ezxi5r 31 16 one one CD cord-293714-s6ezxi5r 31 17 or or CC cord-293714-s6ezxi5r 31 18 more more RBR cord-293714-s6ezxi5r 31 19 widely widely RB cord-293714-s6ezxi5r 31 20 distributed distribute VBN cord-293714-s6ezxi5r 31 21 infectious infectious JJ cord-293714-s6ezxi5r 31 22 agents agent NNS cord-293714-s6ezxi5r 31 23 in in IN cord-293714-s6ezxi5r 31 24 genetically genetically RB cord-293714-s6ezxi5r 31 25 susceptible susceptible JJ cord-293714-s6ezxi5r 31 26 individuals individual NNS cord-293714-s6ezxi5r 31 27 , , , cord-293714-s6ezxi5r 31 28 but but CC cord-293714-s6ezxi5r 31 29 it -PRON- PRP cord-293714-s6ezxi5r 31 30 still still RB cord-293714-s6ezxi5r 31 31 remains remain VBZ cord-293714-s6ezxi5r 31 32 a a DT cord-293714-s6ezxi5r 31 33 medical medical JJ cord-293714-s6ezxi5r 31 34 enigma enigma NN cord-293714-s6ezxi5r 31 35 . . . cord-293714-s6ezxi5r 32 1 The the DT cord-293714-s6ezxi5r 32 2 main main JJ cord-293714-s6ezxi5r 32 3 aim aim NN cord-293714-s6ezxi5r 32 4 of of IN cord-293714-s6ezxi5r 32 5 this this DT cord-293714-s6ezxi5r 32 6 review review NN cord-293714-s6ezxi5r 32 7 is be VBZ cord-293714-s6ezxi5r 32 8 to to TO cord-293714-s6ezxi5r 32 9 analyse analyse VB cord-293714-s6ezxi5r 32 10 the the DT cord-293714-s6ezxi5r 32 11 available available JJ cord-293714-s6ezxi5r 32 12 evidence evidence NN cord-293714-s6ezxi5r 32 13 suggesting suggest VBG cord-293714-s6ezxi5r 32 14 that that IN cord-293714-s6ezxi5r 32 15 KS KS NNP cord-293714-s6ezxi5r 32 16 may may MD cord-293714-s6ezxi5r 32 17 have have VB cord-293714-s6ezxi5r 32 18 an an DT cord-293714-s6ezxi5r 32 19 infectious infectious JJ cord-293714-s6ezxi5r 32 20 origin origin NN cord-293714-s6ezxi5r 32 21 . . . cord-293714-s6ezxi5r 33 1 PubMed PubMed NNP cord-293714-s6ezxi5r 33 2 was be VBD cord-293714-s6ezxi5r 33 3 used use VBN cord-293714-s6ezxi5r 33 4 to to TO cord-293714-s6ezxi5r 33 5 search search VB cord-293714-s6ezxi5r 33 6 for for IN cord-293714-s6ezxi5r 33 7 all all DT cord-293714-s6ezxi5r 33 8 of of IN cord-293714-s6ezxi5r 33 9 the the DT cord-293714-s6ezxi5r 33 10 studies study NNS cord-293714-s6ezxi5r 33 11 published publish VBN cord-293714-s6ezxi5r 33 12 over over IN cord-293714-s6ezxi5r 33 13 the the DT cord-293714-s6ezxi5r 33 14 last last JJ cord-293714-s6ezxi5r 33 15 15 15 CD cord-293714-s6ezxi5r 33 16 years year NNS cord-293714-s6ezxi5r 33 17 using use VBG cord-293714-s6ezxi5r 33 18 the the DT cord-293714-s6ezxi5r 33 19 key key JJ cord-293714-s6ezxi5r 33 20 words word NNS cord-293714-s6ezxi5r 33 21 : : : cord-293714-s6ezxi5r 33 22 " " `` cord-293714-s6ezxi5r 33 23 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 33 24 syndrome syndrome NN cord-293714-s6ezxi5r 33 25 " " '' cord-293714-s6ezxi5r 33 26 or or CC cord-293714-s6ezxi5r 33 27 " " `` cord-293714-s6ezxi5r 33 28 mucocutaneous mucocutaneous JJ cord-293714-s6ezxi5r 33 29 lymph lymph NN cord-293714-s6ezxi5r 33 30 node node NN cord-293714-s6ezxi5r 33 31 syndrome syndrome NN cord-293714-s6ezxi5r 33 32 " " '' cord-293714-s6ezxi5r 33 33 and and CC cord-293714-s6ezxi5r 33 34 " " `` cord-293714-s6ezxi5r 33 35 infectious infectious JJ cord-293714-s6ezxi5r 33 36 disease disease NN cord-293714-s6ezxi5r 33 37 " " '' cord-293714-s6ezxi5r 33 38 or or CC cord-293714-s6ezxi5r 33 39 " " `` cord-293714-s6ezxi5r 33 40 genetics genetic NNS cord-293714-s6ezxi5r 33 41 " " '' cord-293714-s6ezxi5r 33 42 or or CC cord-293714-s6ezxi5r 33 43 " " `` cord-293714-s6ezxi5r 33 44 vasculitis vasculitis JJ cord-293714-s6ezxi5r 33 45 " " '' cord-293714-s6ezxi5r 33 46 or or CC cord-293714-s6ezxi5r 33 47 " " `` cord-293714-s6ezxi5r 33 48 pathogenesis pathogenesis NN cord-293714-s6ezxi5r 33 49 " " '' cord-293714-s6ezxi5r 33 50 . . . cord-293714-s6ezxi5r 34 1 More More JJR cord-293714-s6ezxi5r 34 2 than than IN cord-293714-s6ezxi5r 34 3 1300 1300 CD cord-293714-s6ezxi5r 34 4 articles article NNS cord-293714-s6ezxi5r 34 5 were be VBD cord-293714-s6ezxi5r 34 6 found find VBN cord-293714-s6ezxi5r 34 7 , , , cord-293714-s6ezxi5r 34 8 but but CC cord-293714-s6ezxi5r 34 9 only only RB cord-293714-s6ezxi5r 34 10 those those DT cord-293714-s6ezxi5r 34 11 published publish VBN cord-293714-s6ezxi5r 34 12 in in IN cord-293714-s6ezxi5r 34 13 English English NNP cord-293714-s6ezxi5r 34 14 or or CC cord-293714-s6ezxi5r 34 15 providing provide VBG cord-293714-s6ezxi5r 34 16 evidence evidence NN cord-293714-s6ezxi5r 34 17 - - HYPH cord-293714-s6ezxi5r 34 18 based base VBN cord-293714-s6ezxi5r 34 19 data datum NNS cord-293714-s6ezxi5r 34 20 were be VBD cord-293714-s6ezxi5r 34 21 included include VBN cord-293714-s6ezxi5r 34 22 in in IN cord-293714-s6ezxi5r 34 23 the the DT cord-293714-s6ezxi5r 34 24 evaluation evaluation NN cord-293714-s6ezxi5r 34 25 . . . cord-293714-s6ezxi5r 35 1 Various various JJ cord-293714-s6ezxi5r 35 2 levels level NNS cord-293714-s6ezxi5r 35 3 of of IN cord-293714-s6ezxi5r 35 4 evidence evidence NN cord-293714-s6ezxi5r 35 5 support support VBP cord-293714-s6ezxi5r 35 6 the the DT cord-293714-s6ezxi5r 35 7 hypothesis hypothesis NN cord-293714-s6ezxi5r 35 8 that that IN cord-293714-s6ezxi5r 35 9 KS KS NNP cord-293714-s6ezxi5r 35 10 is be VBZ cord-293714-s6ezxi5r 35 11 a a DT cord-293714-s6ezxi5r 35 12 complex complex JJ cord-293714-s6ezxi5r 35 13 disease disease NN cord-293714-s6ezxi5r 35 14 initiated initiate VBN cord-293714-s6ezxi5r 35 15 by by IN cord-293714-s6ezxi5r 35 16 an an DT cord-293714-s6ezxi5r 35 17 infection infection NN cord-293714-s6ezxi5r 35 18 due due IN cord-293714-s6ezxi5r 35 19 to to IN cord-293714-s6ezxi5r 35 20 one one CD cord-293714-s6ezxi5r 35 21 or or CC cord-293714-s6ezxi5r 35 22 more more JJR cord-293714-s6ezxi5r 35 23 pathogens pathogen NNS cord-293714-s6ezxi5r 35 24 ( ( -LRB- cord-293714-s6ezxi5r 35 25 Table table NN cord-293714-s6ezxi5r 35 26 2 2 CD cord-293714-s6ezxi5r 35 27 ) ) -RRB- cord-293714-s6ezxi5r 35 28 . . . cord-293714-s6ezxi5r 36 1 However however RB cord-293714-s6ezxi5r 36 2 , , , cord-293714-s6ezxi5r 36 3 no no DT cord-293714-s6ezxi5r 36 4 strict strict JJ cord-293714-s6ezxi5r 36 5 and and CC cord-293714-s6ezxi5r 36 6 unmistakable unmistakable JJ cord-293714-s6ezxi5r 36 7 correlation correlation NN cord-293714-s6ezxi5r 36 8 between between IN cord-293714-s6ezxi5r 36 9 specific specific JJ cord-293714-s6ezxi5r 36 10 infectious infectious JJ cord-293714-s6ezxi5r 36 11 agents agent NNS cord-293714-s6ezxi5r 36 12 and and CC cord-293714-s6ezxi5r 36 13 the the DT cord-293714-s6ezxi5r 36 14 development development NN cord-293714-s6ezxi5r 36 15 of of IN cord-293714-s6ezxi5r 36 16 the the DT cord-293714-s6ezxi5r 36 17 disease disease NN cord-293714-s6ezxi5r 36 18 has have VBZ cord-293714-s6ezxi5r 36 19 ever ever RB cord-293714-s6ezxi5r 36 20 been be VBN cord-293714-s6ezxi5r 36 21 identified identify VBN cord-293714-s6ezxi5r 36 22 . . . cord-293714-s6ezxi5r 37 1 A a DT cord-293714-s6ezxi5r 37 2 number number NN cord-293714-s6ezxi5r 37 3 of of IN cord-293714-s6ezxi5r 37 4 bacterial bacterial JJ cord-293714-s6ezxi5r 37 5 and and CC cord-293714-s6ezxi5r 37 6 viral viral JJ cord-293714-s6ezxi5r 37 7 infectious infectious JJ cord-293714-s6ezxi5r 37 8 agents agent NNS cord-293714-s6ezxi5r 37 9 have have VBP cord-293714-s6ezxi5r 37 10 been be VBN cord-293714-s6ezxi5r 37 11 sporadically sporadically RB cord-293714-s6ezxi5r 37 12 isolated isolate VBN cord-293714-s6ezxi5r 37 13 from from IN cord-293714-s6ezxi5r 37 14 KS KS NNP cord-293714-s6ezxi5r 37 15 patients patient NNS cord-293714-s6ezxi5r 37 16 . . . cord-293714-s6ezxi5r 38 1 The the DT cord-293714-s6ezxi5r 38 2 most most RBS cord-293714-s6ezxi5r 38 3 frequently frequently RB cord-293714-s6ezxi5r 38 4 implicated implicate VBN cord-293714-s6ezxi5r 38 5 bacteria bacteria NNS cord-293714-s6ezxi5r 38 6 are be VBP cord-293714-s6ezxi5r 38 7 Staphylococcus Staphylococcus NNP cord-293714-s6ezxi5r 38 8 aureus aureus NN cord-293714-s6ezxi5r 38 9 , , , cord-293714-s6ezxi5r 38 10 6 6 CD cord-293714-s6ezxi5r 38 11 Streptococcus streptococcus NN cord-293714-s6ezxi5r 38 12 pyogenes pyogene NNS cord-293714-s6ezxi5r 38 13 , , , cord-293714-s6ezxi5r 38 14 7 7 CD cord-293714-s6ezxi5r 38 15 and and CC cord-293714-s6ezxi5r 38 16 atypical atypical JJ cord-293714-s6ezxi5r 38 17 pathogens pathogen NNS cord-293714-s6ezxi5r 38 18 , , , cord-293714-s6ezxi5r 38 19 8e10 8e10 CD cord-293714-s6ezxi5r 38 20 and and CC cord-293714-s6ezxi5r 38 21 the the DT cord-293714-s6ezxi5r 38 22 viruses virus NNS cord-293714-s6ezxi5r 38 23 associated associate VBN cord-293714-s6ezxi5r 38 24 with with IN cord-293714-s6ezxi5r 38 25 KS KS NNP cord-293714-s6ezxi5r 38 26 over over IN cord-293714-s6ezxi5r 38 27 recent recent JJ cord-293714-s6ezxi5r 38 28 years year NNS cord-293714-s6ezxi5r 38 29 are be VBP cord-293714-s6ezxi5r 38 30 EpsteineBarr EpsteineBarr NNP cord-293714-s6ezxi5r 38 31 virus virus NN cord-293714-s6ezxi5r 38 32 , , , cord-293714-s6ezxi5r 38 33 11 11 CD cord-293714-s6ezxi5r 38 34 adenovirus adenovirus NN cord-293714-s6ezxi5r 38 35 , , , cord-293714-s6ezxi5r 38 36 12 12 CD cord-293714-s6ezxi5r 38 37 parvovirus parvovirus NN cord-293714-s6ezxi5r 38 38 B19 B19 NNP cord-293714-s6ezxi5r 38 39 , , , cord-293714-s6ezxi5r 38 40 13 13 CD cord-293714-s6ezxi5r 38 41 herpesvirus herpesvirus NN cord-293714-s6ezxi5r 38 42 6 6 CD cord-293714-s6ezxi5r 38 43 , , , cord-293714-s6ezxi5r 38 44 14 14 CD cord-293714-s6ezxi5r 38 45 parainfluenza parainfluenza NNP cord-293714-s6ezxi5r 38 46 type type NNP cord-293714-s6ezxi5r 38 47 3 3 CD cord-293714-s6ezxi5r 38 48 , , , cord-293714-s6ezxi5r 38 49 15 15 CD cord-293714-s6ezxi5r 38 50 measles measle NNS cord-293714-s6ezxi5r 38 51 , , , cord-293714-s6ezxi5r 38 52 16 16 CD cord-293714-s6ezxi5r 38 53 rotavirus rotavirus NN cord-293714-s6ezxi5r 38 54 , , , cord-293714-s6ezxi5r 38 55 17 17 CD cord-293714-s6ezxi5r 38 56 dengue dengue NN cord-293714-s6ezxi5r 38 57 virus virus NN cord-293714-s6ezxi5r 38 58 , , , cord-293714-s6ezxi5r 38 59 18 18 CD cord-293714-s6ezxi5r 38 60 and and CC cord-293714-s6ezxi5r 38 61 human human JJ cord-293714-s6ezxi5r 38 62 immunodeficiency immunodeficiency NN cord-293714-s6ezxi5r 38 63 virus virus NN cord-293714-s6ezxi5r 38 64 . . . cord-293714-s6ezxi5r 39 1 13 13 CD cord-293714-s6ezxi5r 39 2 Varicella Varicella NNP cord-293714-s6ezxi5r 39 3 , , , cord-293714-s6ezxi5r 39 4 19 19 CD cord-293714-s6ezxi5r 39 5 2009 2009 CD cord-293714-s6ezxi5r 40 1 H1N1 H1N1 NNP cord-293714-s6ezxi5r 40 2 pandemic pandemic NN cord-293714-s6ezxi5r 40 3 influenza influenza NN cord-293714-s6ezxi5r 40 4 20 20 CD cord-293714-s6ezxi5r 40 5 and and CC cord-293714-s6ezxi5r 40 6 Coxsackie Coxsackie NNP cord-293714-s6ezxi5r 40 7 B3 B3 NNP cord-293714-s6ezxi5r 40 8 virus virus NN cord-293714-s6ezxi5r 40 9 21 21 CD cord-293714-s6ezxi5r 40 10 have have VBP cord-293714-s6ezxi5r 40 11 also also RB cord-293714-s6ezxi5r 40 12 been be VBN cord-293714-s6ezxi5r 40 13 described describe VBN cord-293714-s6ezxi5r 40 14 in in IN cord-293714-s6ezxi5r 40 15 patients patient NNS cord-293714-s6ezxi5r 40 16 with with IN cord-293714-s6ezxi5r 40 17 KS KS NNP cord-293714-s6ezxi5r 40 18 , , , cord-293714-s6ezxi5r 40 19 but but CC cord-293714-s6ezxi5r 40 20 they -PRON- PRP cord-293714-s6ezxi5r 40 21 were be VBD cord-293714-s6ezxi5r 40 22 equally equally RB cord-293714-s6ezxi5r 40 23 found find VBN cord-293714-s6ezxi5r 40 24 in in IN cord-293714-s6ezxi5r 40 25 the the DT cord-293714-s6ezxi5r 40 26 blood blood NN cord-293714-s6ezxi5r 40 27 or or CC cord-293714-s6ezxi5r 40 28 body body NN cord-293714-s6ezxi5r 40 29 fluids fluid NNS cord-293714-s6ezxi5r 40 30 of of IN cord-293714-s6ezxi5r 40 31 both both DT cord-293714-s6ezxi5r 40 32 patients patient NNS cord-293714-s6ezxi5r 40 33 and and CC cord-293714-s6ezxi5r 40 34 healthy healthy JJ cord-293714-s6ezxi5r 40 35 subjects subject NNS cord-293714-s6ezxi5r 40 36 . . . cord-293714-s6ezxi5r 41 1 Moreover moreover RB cord-293714-s6ezxi5r 41 2 , , , cord-293714-s6ezxi5r 41 3 no no DT cord-293714-s6ezxi5r 41 4 relationship relationship NN cord-293714-s6ezxi5r 41 5 was be VBD cord-293714-s6ezxi5r 41 6 reported report VBN cord-293714-s6ezxi5r 41 7 between between IN cord-293714-s6ezxi5r 41 8 KS KS NNP cord-293714-s6ezxi5r 41 9 and and CC cord-293714-s6ezxi5r 41 10 the the DT cord-293714-s6ezxi5r 41 11 circulation circulation NN cord-293714-s6ezxi5r 41 12 of of IN cord-293714-s6ezxi5r 41 13 the the DT cord-293714-s6ezxi5r 41 14 commonest common JJS cord-293714-s6ezxi5r 41 15 respiratory respiratory JJ cord-293714-s6ezxi5r 41 16 viruses virus NNS cord-293714-s6ezxi5r 41 17 . . . cord-293714-s6ezxi5r 42 1 22 22 CD cord-293714-s6ezxi5r 43 1 The the DT cord-293714-s6ezxi5r 43 2 most most RBS cord-293714-s6ezxi5r 43 3 recent recent JJ cord-293714-s6ezxi5r 43 4 and and CC cord-293714-s6ezxi5r 43 5 numerous numerous JJ cord-293714-s6ezxi5r 43 6 studies study NNS cord-293714-s6ezxi5r 43 7 of of IN cord-293714-s6ezxi5r 43 8 KS KS NNP cord-293714-s6ezxi5r 43 9 - - HYPH cord-293714-s6ezxi5r 43 10 related relate VBN cord-293714-s6ezxi5r 43 11 viruses virus NNS cord-293714-s6ezxi5r 43 12 have have VBP cord-293714-s6ezxi5r 43 13 postulated postulate VBN cord-293714-s6ezxi5r 43 14 the the DT cord-293714-s6ezxi5r 43 15 etiological etiological JJ cord-293714-s6ezxi5r 43 16 role role NN cord-293714-s6ezxi5r 43 17 of of IN cord-293714-s6ezxi5r 43 18 human human JJ cord-293714-s6ezxi5r 43 19 coronavirus coronavirus NN cord-293714-s6ezxi5r 43 20 ( ( -LRB- cord-293714-s6ezxi5r 43 21 HCoV HCoV NNP cord-293714-s6ezxi5r 43 22 ) ) -RRB- cord-293714-s6ezxi5r 44 1 NL63 NL63 NNP cord-293714-s6ezxi5r 44 2 and and CC cord-293714-s6ezxi5r 44 3 bocavirus bocavirus NNP cord-293714-s6ezxi5r 44 4 , , , cord-293714-s6ezxi5r 45 1 23e25 23e25 CD cord-293714-s6ezxi5r 46 1 but but CC cord-293714-s6ezxi5r 46 2 this this DT cord-293714-s6ezxi5r 46 3 has have VBZ cord-293714-s6ezxi5r 46 4 not not RB cord-293714-s6ezxi5r 46 5 been be VBN cord-293714-s6ezxi5r 46 6 confirmed confirm VBN cord-293714-s6ezxi5r 46 7 by by IN cord-293714-s6ezxi5r 46 8 subsequent subsequent JJ cord-293714-s6ezxi5r 46 9 studies study NNS cord-293714-s6ezxi5r 46 10 . . . cord-293714-s6ezxi5r 47 1 In in IN cord-293714-s6ezxi5r 47 2 order order NN cord-293714-s6ezxi5r 47 3 to to TO cord-293714-s6ezxi5r 47 4 evaluate evaluate VB cord-293714-s6ezxi5r 47 5 the the DT cord-293714-s6ezxi5r 47 6 importance importance NN cord-293714-s6ezxi5r 47 7 of of IN cord-293714-s6ezxi5r 47 8 HCoV HCoV NNP cord-293714-s6ezxi5r 47 9 - - HYPH cord-293714-s6ezxi5r 47 10 NL63 NL63 NNP cord-293714-s6ezxi5r 47 11 in in IN cord-293714-s6ezxi5r 47 12 KS KS NNP cord-293714-s6ezxi5r 47 13 , , , cord-293714-s6ezxi5r 47 14 Shimizu Shimizu NNP cord-293714-s6ezxi5r 47 15 et et NNP cord-293714-s6ezxi5r 47 16 al al NNP cord-293714-s6ezxi5r 47 17 . . NNP cord-293714-s6ezxi5r 47 18 established establish VBD cord-293714-s6ezxi5r 47 19 a a DT cord-293714-s6ezxi5r 47 20 multi multi JJ cord-293714-s6ezxi5r 47 21 - - JJ cord-293714-s6ezxi5r 47 22 institutional institutional JJ cord-293714-s6ezxi5r 47 23 collaborative collaborative JJ cord-293714-s6ezxi5r 47 24 research research NN cord-293714-s6ezxi5r 47 25 project project NN cord-293714-s6ezxi5r 47 26 to to TO cord-293714-s6ezxi5r 47 27 test test VB cord-293714-s6ezxi5r 47 28 respiratory respiratory JJ cord-293714-s6ezxi5r 47 29 samples sample NNS cord-293714-s6ezxi5r 47 30 using use VBG cord-293714-s6ezxi5r 47 31 realtime realtime JJ cord-293714-s6ezxi5r 47 32 polymerase polymerase NN cord-293714-s6ezxi5r 47 33 chain chain NN cord-293714-s6ezxi5r 47 34 reaction reaction NN cord-293714-s6ezxi5r 47 35 ( ( -LRB- cord-293714-s6ezxi5r 47 36 RT RT NNP cord-293714-s6ezxi5r 47 37 - - HYPH cord-293714-s6ezxi5r 47 38 PCR PCR NNP cord-293714-s6ezxi5r 47 39 ) ) -RRB- cord-293714-s6ezxi5r 47 40 , , , cord-293714-s6ezxi5r 47 41 and and CC cord-293714-s6ezxi5r 47 42 found find VBD cord-293714-s6ezxi5r 47 43 that that IN cord-293714-s6ezxi5r 47 44 only only RB cord-293714-s6ezxi5r 47 45 one one CD cord-293714-s6ezxi5r 47 46 out out IN cord-293714-s6ezxi5r 47 47 of of IN cord-293714-s6ezxi5r 47 48 48 48 CD cord-293714-s6ezxi5r 47 49 KS KS NNP cord-293714-s6ezxi5r 47 50 patients patient NNS cord-293714-s6ezxi5r 47 51 ( ( -LRB- cord-293714-s6ezxi5r 47 52 2 2 CD cord-293714-s6ezxi5r 47 53 % % NN cord-293714-s6ezxi5r 47 54 ) ) -RRB- cord-293714-s6ezxi5r 47 55 was be VBD cord-293714-s6ezxi5r 47 56 positive positive JJ cord-293714-s6ezxi5r 47 57 26 26 CD cord-293714-s6ezxi5r 47 58 ; ; : cord-293714-s6ezxi5r 47 59 Dominguez Dominguez NNP cord-293714-s6ezxi5r 47 60 et et NNP cord-293714-s6ezxi5r 47 61 al al NNP cord-293714-s6ezxi5r 47 62 . . . cord-293714-s6ezxi5r 48 1 found find VBD cord-293714-s6ezxi5r 48 2 exactly exactly RB cord-293714-s6ezxi5r 48 3 the the DT cord-293714-s6ezxi5r 48 4 same same JJ cord-293714-s6ezxi5r 48 5 prevalence prevalence NN cord-293714-s6ezxi5r 48 6 in in IN cord-293714-s6ezxi5r 48 7 nasopharyngeal nasopharyngeal JJ cord-293714-s6ezxi5r 48 8 wash wash NN cord-293714-s6ezxi5r 48 9 samples sample NNS cord-293714-s6ezxi5r 48 10 from from IN cord-293714-s6ezxi5r 48 11 KS KS NNP cord-293714-s6ezxi5r 48 12 patients patient NNS cord-293714-s6ezxi5r 48 13 and and CC cord-293714-s6ezxi5r 48 14 healthy healthy JJ cord-293714-s6ezxi5r 48 15 controls control NNS cord-293714-s6ezxi5r 48 16 over over IN cord-293714-s6ezxi5r 48 17 a a DT cord-293714-s6ezxi5r 48 18 period period NN cord-293714-s6ezxi5r 48 19 of of IN cord-293714-s6ezxi5r 48 20 seven seven CD cord-293714-s6ezxi5r 48 21 months month NNS cord-293714-s6ezxi5r 48 22 27 27 CD cord-293714-s6ezxi5r 48 23 ; ; : cord-293714-s6ezxi5r 48 24 and and CC cord-293714-s6ezxi5r 48 25 Lehmann Lehmann NNP cord-293714-s6ezxi5r 48 26 et et NNP cord-293714-s6ezxi5r 48 27 al al NNP cord-293714-s6ezxi5r 48 28 . . . cord-293714-s6ezxi5r 49 1 measured measure VBD cord-293714-s6ezxi5r 49 2 the the DT cord-293714-s6ezxi5r 49 3 concentrations concentration NNS cord-293714-s6ezxi5r 49 4 of of IN cord-293714-s6ezxi5r 49 5 IgG IgG NNP cord-293714-s6ezxi5r 49 6 , , , cord-293714-s6ezxi5r 49 7 IgM IgM NNP cord-293714-s6ezxi5r 49 8 and and CC cord-293714-s6ezxi5r 49 9 IgA IgA NNP cord-293714-s6ezxi5r 49 10 antibodies antibody NNS cord-293714-s6ezxi5r 49 11 against against IN cord-293714-s6ezxi5r 49 12 HCoV hcov ADD cord-293714-s6ezxi5r 49 13 NL63 NL63 NNP cord-293714-s6ezxi5r 49 14 and and CC cord-293714-s6ezxi5r 49 15 OC43 OC43 NNP cord-293714-s6ezxi5r 49 16 in in IN cord-293714-s6ezxi5r 49 17 the the DT cord-293714-s6ezxi5r 49 18 blood blood NN cord-293714-s6ezxi5r 49 19 of of IN cord-293714-s6ezxi5r 49 20 children child NNS cord-293714-s6ezxi5r 49 21 showing show VBG cord-293714-s6ezxi5r 49 22 the the DT cord-293714-s6ezxi5r 49 23 signs sign NNS cord-293714-s6ezxi5r 49 24 and and CC cord-293714-s6ezxi5r 49 25 symptoms symptom NNS cord-293714-s6ezxi5r 49 26 of of IN cord-293714-s6ezxi5r 49 27 KS KS NNP cord-293714-s6ezxi5r 49 28 for for IN cord-293714-s6ezxi5r 49 29 3e10 3e10 CD cord-293714-s6ezxi5r 49 30 days day NNS cord-293714-s6ezxi5r 49 31 and and CC cord-293714-s6ezxi5r 49 32 healthy healthy JJ cord-293714-s6ezxi5r 49 33 controls control NNS cord-293714-s6ezxi5r 49 34 , , , cord-293714-s6ezxi5r 49 35 but but CC cord-293714-s6ezxi5r 49 36 did do VBD cord-293714-s6ezxi5r 49 37 not not RB cord-293714-s6ezxi5r 49 38 find find VB cord-293714-s6ezxi5r 49 39 any any DT cord-293714-s6ezxi5r 49 40 difference difference NN cord-293714-s6ezxi5r 49 41 between between IN cord-293714-s6ezxi5r 49 42 the the DT cord-293714-s6ezxi5r 49 43 two two CD cord-293714-s6ezxi5r 49 44 groups group NNS cord-293714-s6ezxi5r 49 45 . . . cord-293714-s6ezxi5r 50 1 28 28 CD cord-293714-s6ezxi5r 51 1 The the DT cord-293714-s6ezxi5r 51 2 data datum NNS cord-293714-s6ezxi5r 51 3 regarding regard VBG cord-293714-s6ezxi5r 51 4 bocavirus bocavirus NNP cord-293714-s6ezxi5r 51 5 ( ( -LRB- cord-293714-s6ezxi5r 51 6 a a DT cord-293714-s6ezxi5r 51 7 virus virus NN cord-293714-s6ezxi5r 51 8 that that WDT cord-293714-s6ezxi5r 51 9 has have VBZ cord-293714-s6ezxi5r 51 10 recently recently RB cord-293714-s6ezxi5r 51 11 emerged emerge VBN cord-293714-s6ezxi5r 51 12 as as IN cord-293714-s6ezxi5r 51 13 a a DT cord-293714-s6ezxi5r 51 14 possible possible JJ cord-293714-s6ezxi5r 51 15 cause cause NN cord-293714-s6ezxi5r 51 16 of of IN cord-293714-s6ezxi5r 51 17 respiratory respiratory JJ cord-293714-s6ezxi5r 51 18 infection infection NN cord-293714-s6ezxi5r 51 19 ) ) -RRB- cord-293714-s6ezxi5r 51 20 are be VBP cord-293714-s6ezxi5r 51 21 also also RB cord-293714-s6ezxi5r 51 22 unconvincing unconvincing JJ cord-293714-s6ezxi5r 51 23 29 29 CD cord-293714-s6ezxi5r 51 24 : : : cord-293714-s6ezxi5r 51 25 although although IN cord-293714-s6ezxi5r 51 26 it -PRON- PRP cord-293714-s6ezxi5r 51 27 was be VBD cord-293714-s6ezxi5r 51 28 identified identify VBN cord-293714-s6ezxi5r 51 29 in in IN cord-293714-s6ezxi5r 51 30 the the DT cord-293714-s6ezxi5r 51 31 serum serum NN cord-293714-s6ezxi5r 51 32 , , , cord-293714-s6ezxi5r 51 33 stool stool NN cord-293714-s6ezxi5r 51 34 and and CC cord-293714-s6ezxi5r 51 35 cerebrospinal cerebrospinal JJ cord-293714-s6ezxi5r 51 36 fluid fluid NN cord-293714-s6ezxi5r 51 37 of of IN cord-293714-s6ezxi5r 51 38 some some DT cord-293714-s6ezxi5r 51 39 children child NNS cord-293714-s6ezxi5r 51 40 with with IN cord-293714-s6ezxi5r 51 41 KS KS NNP cord-293714-s6ezxi5r 51 42 , , , cord-293714-s6ezxi5r 51 43 no no DT cord-293714-s6ezxi5r 51 44 definitive definitive JJ cord-293714-s6ezxi5r 51 45 conclusion conclusion NN cord-293714-s6ezxi5r 51 46 could could MD cord-293714-s6ezxi5r 51 47 be be VB cord-293714-s6ezxi5r 51 48 drawn draw VBN cord-293714-s6ezxi5r 51 49 concerning concern VBG cord-293714-s6ezxi5r 51 50 its -PRON- PRP$ cord-293714-s6ezxi5r 51 51 etiological etiological JJ cord-293714-s6ezxi5r 51 52 role role NN cord-293714-s6ezxi5r 51 53 . . . cord-293714-s6ezxi5r 52 1 The the DT cord-293714-s6ezxi5r 52 2 limited limited JJ cord-293714-s6ezxi5r 52 3 etiological etiological JJ cord-293714-s6ezxi5r 52 4 importance importance NN cord-293714-s6ezxi5r 52 5 of of IN cord-293714-s6ezxi5r 52 6 the the DT cord-293714-s6ezxi5r 52 7 pathogens pathogen NNS cord-293714-s6ezxi5r 52 8 so so RB cord-293714-s6ezxi5r 52 9 far far RB cord-293714-s6ezxi5r 52 10 identified identify VBN cord-293714-s6ezxi5r 52 11 seems seem VBZ cord-293714-s6ezxi5r 52 12 to to TO cord-293714-s6ezxi5r 52 13 be be VB cord-293714-s6ezxi5r 52 14 supported support VBN cord-293714-s6ezxi5r 52 15 by by IN cord-293714-s6ezxi5r 52 16 the the DT cord-293714-s6ezxi5r 52 17 studies study NNS cord-293714-s6ezxi5r 52 18 of of IN cord-293714-s6ezxi5r 52 19 Benseler Benseler NNP cord-293714-s6ezxi5r 52 20 et et NNP cord-293714-s6ezxi5r 52 21 al al NNP cord-293714-s6ezxi5r 52 22 . . . cord-293714-s6ezxi5r 53 1 30 30 CD cord-293714-s6ezxi5r 53 2 and and CC cord-293714-s6ezxi5r 53 3 Jordan Jordan NNP cord-293714-s6ezxi5r 53 4 - - HYPH cord-293714-s6ezxi5r 53 5 Villegas Villegas NNP cord-293714-s6ezxi5r 53 6 et et NNP cord-293714-s6ezxi5r 53 7 al al NNP cord-293714-s6ezxi5r 53 8 . . NNP cord-293714-s6ezxi5r 53 9 , , , cord-293714-s6ezxi5r 53 10 31 31 CD cord-293714-s6ezxi5r 53 11 who who WP cord-293714-s6ezxi5r 53 12 found find VBD cord-293714-s6ezxi5r 53 13 that that IN cord-293714-s6ezxi5r 53 14 that that IN cord-293714-s6ezxi5r 53 15 concomitant concomitant JJ cord-293714-s6ezxi5r 53 16 infections infection NNS cord-293714-s6ezxi5r 53 17 in in IN cord-293714-s6ezxi5r 53 18 children child NNS cord-293714-s6ezxi5r 53 19 with with IN cord-293714-s6ezxi5r 53 20 KS KS NNP cord-293714-s6ezxi5r 53 21 did do VBD cord-293714-s6ezxi5r 53 22 not not RB cord-293714-s6ezxi5r 53 23 alter alter VB cord-293714-s6ezxi5r 53 24 the the DT cord-293714-s6ezxi5r 53 25 response response NN cord-293714-s6ezxi5r 53 26 to to IN cord-293714-s6ezxi5r 53 27 treatment treatment NN cord-293714-s6ezxi5r 53 28 with with IN cord-293714-s6ezxi5r 53 29 intravenous intravenous JJ cord-293714-s6ezxi5r 53 30 immunoglobulins immunoglobulin NNS cord-293714-s6ezxi5r 53 31 , , , cord-293714-s6ezxi5r 53 32 and and CC cord-293714-s6ezxi5r 53 33 did do VBD cord-293714-s6ezxi5r 53 34 not not RB cord-293714-s6ezxi5r 53 35 influence influence VB cord-293714-s6ezxi5r 53 36 the the DT cord-293714-s6ezxi5r 53 37 risk risk NN cord-293714-s6ezxi5r 53 38 of of IN cord-293714-s6ezxi5r 53 39 coronary coronary JJ cord-293714-s6ezxi5r 53 40 artery artery NN cord-293714-s6ezxi5r 53 41 involvement involvement NN cord-293714-s6ezxi5r 53 42 or or CC cord-293714-s6ezxi5r 53 43 affect affect VB cord-293714-s6ezxi5r 53 44 overall overall JJ cord-293714-s6ezxi5r 53 45 cardiovascular cardiovascular JJ cord-293714-s6ezxi5r 53 46 outcomes outcome NNS cord-293714-s6ezxi5r 53 47 . . . cord-293714-s6ezxi5r 54 1 However however RB cord-293714-s6ezxi5r 54 2 , , , cord-293714-s6ezxi5r 54 3 the the DT cord-293714-s6ezxi5r 54 4 lack lack NN cord-293714-s6ezxi5r 54 5 of of IN cord-293714-s6ezxi5r 54 6 any any DT cord-293714-s6ezxi5r 54 7 clear clear JJ cord-293714-s6ezxi5r 54 8 relationship relationship NN cord-293714-s6ezxi5r 54 9 between between IN cord-293714-s6ezxi5r 54 10 one one CD cord-293714-s6ezxi5r 54 11 or or CC cord-293714-s6ezxi5r 54 12 more more JJR cord-293714-s6ezxi5r 54 13 pathogens pathogen NNS cord-293714-s6ezxi5r 54 14 and and CC cord-293714-s6ezxi5r 54 15 the the DT cord-293714-s6ezxi5r 54 16 development development NN cord-293714-s6ezxi5r 54 17 of of IN cord-293714-s6ezxi5r 54 18 KS KS NNP cord-293714-s6ezxi5r 54 19 does do VBZ cord-293714-s6ezxi5r 54 20 not not RB cord-293714-s6ezxi5r 54 21 exclude exclude VB cord-293714-s6ezxi5r 54 22 the the DT cord-293714-s6ezxi5r 54 23 possibility possibility NN cord-293714-s6ezxi5r 54 24 that that IN cord-293714-s6ezxi5r 54 25 a a DT cord-293714-s6ezxi5r 54 26 real real JJ cord-293714-s6ezxi5r 54 27 infectious infectious JJ cord-293714-s6ezxi5r 54 28 disease disease NN cord-293714-s6ezxi5r 54 29 may may MD cord-293714-s6ezxi5r 54 30 be be VB cord-293714-s6ezxi5r 54 31 involved involve VBN cord-293714-s6ezxi5r 54 32 , , , cord-293714-s6ezxi5r 54 33 and and CC cord-293714-s6ezxi5r 54 34 other other JJ cord-293714-s6ezxi5r 54 35 factors factor NNS cord-293714-s6ezxi5r 54 36 support support VBP cord-293714-s6ezxi5r 54 37 this this DT cord-293714-s6ezxi5r 54 38 hypothesis hypothesis NN cord-293714-s6ezxi5r 54 39 . . . cord-293714-s6ezxi5r 55 1 On on IN cord-293714-s6ezxi5r 55 2 the the DT cord-293714-s6ezxi5r 55 3 other other JJ cord-293714-s6ezxi5r 55 4 hand hand NN cord-293714-s6ezxi5r 55 5 , , , cord-293714-s6ezxi5r 55 6 the the DT cord-293714-s6ezxi5r 55 7 unsuccessful unsuccessful JJ cord-293714-s6ezxi5r 55 8 identification identification NN cord-293714-s6ezxi5r 55 9 of of IN cord-293714-s6ezxi5r 55 10 a a DT cord-293714-s6ezxi5r 55 11 specific specific JJ cord-293714-s6ezxi5r 55 12 pathogen pathogen NN cord-293714-s6ezxi5r 55 13 to to TO cord-293714-s6ezxi5r 55 14 which which WDT cord-293714-s6ezxi5r 55 15 KS KS NNP cord-293714-s6ezxi5r 55 16 could could MD cord-293714-s6ezxi5r 55 17 be be VB cord-293714-s6ezxi5r 55 18 ascribed ascribe VBN cord-293714-s6ezxi5r 55 19 has have VBZ cord-293714-s6ezxi5r 55 20 led lead VBN cord-293714-s6ezxi5r 55 21 some some DT cord-293714-s6ezxi5r 55 22 authors author NNS cord-293714-s6ezxi5r 55 23 to to TO cord-293714-s6ezxi5r 55 24 postulate postulate VB cord-293714-s6ezxi5r 55 25 that that IN cord-293714-s6ezxi5r 55 26 variants variant NNS cord-293714-s6ezxi5r 55 27 of of IN cord-293714-s6ezxi5r 55 28 normal normal JJ cord-293714-s6ezxi5r 55 29 flora flora NNS cord-293714-s6ezxi5r 55 30 in in IN cord-293714-s6ezxi5r 55 31 the the DT cord-293714-s6ezxi5r 55 32 gut gut NN cord-293714-s6ezxi5r 55 33 , , , cord-293714-s6ezxi5r 55 34 oral oral JJ cord-293714-s6ezxi5r 55 35 cavity cavity NN cord-293714-s6ezxi5r 55 36 or or CC cord-293714-s6ezxi5r 55 37 skin skin NN cord-293714-s6ezxi5r 55 38 of of IN cord-293714-s6ezxi5r 55 39 young young JJ cord-293714-s6ezxi5r 55 40 children child NNS cord-293714-s6ezxi5r 55 41 with with IN cord-293714-s6ezxi5r 55 42 a a DT cord-293714-s6ezxi5r 55 43 genetic genetic JJ cord-293714-s6ezxi5r 55 44 defect defect NN cord-293714-s6ezxi5r 55 45 of of IN cord-293714-s6ezxi5r 55 46 proper proper JJ cord-293714-s6ezxi5r 55 47 immune immune JJ cord-293714-s6ezxi5r 55 48 maturation maturation NN cord-293714-s6ezxi5r 55 49 do do VBP cord-293714-s6ezxi5r 55 50 not not RB cord-293714-s6ezxi5r 55 51 induce induce VB cord-293714-s6ezxi5r 55 52 immune immune JJ cord-293714-s6ezxi5r 55 53 tolerance tolerance NN cord-293714-s6ezxi5r 55 54 as as IN cord-293714-s6ezxi5r 55 55 self self NN cord-293714-s6ezxi5r 55 56 commensals commensal NNS cord-293714-s6ezxi5r 55 57 , , , cord-293714-s6ezxi5r 55 58 but but CC cord-293714-s6ezxi5r 55 59 rather rather RB cord-293714-s6ezxi5r 55 60 induce induce VB cord-293714-s6ezxi5r 55 61 an an DT cord-293714-s6ezxi5r 55 62 imbalance imbalance NN cord-293714-s6ezxi5r 55 63 of of IN cord-293714-s6ezxi5r 55 64 the the DT cord-293714-s6ezxi5r 55 65 immune immune JJ cord-293714-s6ezxi5r 55 66 system system NN cord-293714-s6ezxi5r 55 67 , , , cord-293714-s6ezxi5r 55 68 leading lead VBG cord-293714-s6ezxi5r 55 69 to to IN cord-293714-s6ezxi5r 55 70 a a DT cord-293714-s6ezxi5r 55 71 hyperimmune hyperimmune NNP cord-293714-s6ezxi5r 55 72 reaction reaction NN cord-293714-s6ezxi5r 55 73 and and CC cord-293714-s6ezxi5r 55 74 the the DT cord-293714-s6ezxi5r 55 75 manifesting manifest VBG cord-293714-s6ezxi5r 55 76 KS KS NNP cord-293714-s6ezxi5r 55 77 . . . cord-293714-s6ezxi5r 56 1 32 32 CD cord-293714-s6ezxi5r 56 2 Table Table NNP cord-293714-s6ezxi5r 56 3 1 1 CD cord-293714-s6ezxi5r 56 4 Laboratory Laboratory NNP cord-293714-s6ezxi5r 56 5 findings finding NNS cord-293714-s6ezxi5r 56 6 supporting support VBG cord-293714-s6ezxi5r 56 7 a a DT cord-293714-s6ezxi5r 56 8 diagnosis diagnosis NN cord-293714-s6ezxi5r 56 9 of of IN cord-293714-s6ezxi5r 56 10 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 56 11 syndrome syndrome NN cord-293714-s6ezxi5r 56 12 . . . cord-293714-s6ezxi5r 57 1 1 1 LS cord-293714-s6ezxi5r 57 2 . . . cord-293714-s6ezxi5r 58 1 C C NNP cord-293714-s6ezxi5r 58 2 - - HYPH cord-293714-s6ezxi5r 58 3 reactive reactive JJ cord-293714-s6ezxi5r 58 4 protein protein NN cord-293714-s6ezxi5r 58 5 ! ! . cord-293714-s6ezxi5r 59 1 3.0 3.0 CD cord-293714-s6ezxi5r 59 2 mg mg NNP cord-293714-s6ezxi5r 59 3 / / SYM cord-293714-s6ezxi5r 59 4 dL dl NN cord-293714-s6ezxi5r 59 5 2 2 CD cord-293714-s6ezxi5r 59 6 . . . cord-293714-s6ezxi5r 60 1 Erythrocyte Erythrocyte NNP cord-293714-s6ezxi5r 60 2 sedimentation sedimentation NN cord-293714-s6ezxi5r 60 3 rate rate NN cord-293714-s6ezxi5r 60 4 ! ! . cord-293714-s6ezxi5r 61 1 40 40 CD cord-293714-s6ezxi5r 61 2 mm mm NNP cord-293714-s6ezxi5r 61 3 / / SYM cord-293714-s6ezxi5r 61 4 h h NN cord-293714-s6ezxi5r 61 5 3 3 CD cord-293714-s6ezxi5r 61 6 . . . cord-293714-s6ezxi5r 62 1 Albumin albumin NN cord-293714-s6ezxi5r 62 2 3.0 3.0 CD cord-293714-s6ezxi5r 63 1 g g NNP cord-293714-s6ezxi5r 63 2 / / SYM cord-293714-s6ezxi5r 63 3 dL dl NN cord-293714-s6ezxi5r 63 4 4 4 CD cord-293714-s6ezxi5r 63 5 . . . cord-293714-s6ezxi5r 64 1 Age age NN cord-293714-s6ezxi5r 64 2 - - HYPH cord-293714-s6ezxi5r 64 3 relative relative JJ cord-293714-s6ezxi5r 64 4 anaemia anaemia NN cord-293714-s6ezxi5r 64 5 5 5 CD cord-293714-s6ezxi5r 64 6 . . . cord-293714-s6ezxi5r 65 1 High high JJ cord-293714-s6ezxi5r 65 2 alanine alanine JJ cord-293714-s6ezxi5r 65 3 aminotransferase aminotransferase NN cord-293714-s6ezxi5r 65 4 levels level NNS cord-293714-s6ezxi5r 65 5 6 6 CD cord-293714-s6ezxi5r 65 6 . . . cord-293714-s6ezxi5r 66 1 Platelet platelet NN cord-293714-s6ezxi5r 66 2 count count NN cord-293714-s6ezxi5r 66 3 ! ! . cord-293714-s6ezxi5r 67 1 450,000 450,000 CD cord-293714-s6ezxi5r 67 2 / / SYM cord-293714-s6ezxi5r 67 3 mm mm NNP cord-293714-s6ezxi5r 67 4 3 3 CD cord-293714-s6ezxi5r 67 5 in in IN cord-293714-s6ezxi5r 67 6 the the DT cord-293714-s6ezxi5r 67 7 subacute subacute JJ cord-293714-s6ezxi5r 67 8 phase phase NN cord-293714-s6ezxi5r 67 9 of of IN cord-293714-s6ezxi5r 67 10 the the DT cord-293714-s6ezxi5r 67 11 disease disease NN cord-293714-s6ezxi5r 67 12 7 7 CD cord-293714-s6ezxi5r 67 13 . . . cord-293714-s6ezxi5r 68 1 White white JJ cord-293714-s6ezxi5r 68 2 blood blood NN cord-293714-s6ezxi5r 68 3 cell cell NN cord-293714-s6ezxi5r 68 4 count count NN cord-293714-s6ezxi5r 68 5 ! ! . cord-293714-s6ezxi5r 69 1 15,000 15,000 CD cord-293714-s6ezxi5r 69 2 / / SYM cord-293714-s6ezxi5r 69 3 mm mm NNP cord-293714-s6ezxi5r 69 4 3 3 CD cord-293714-s6ezxi5r 69 5 8 8 CD cord-293714-s6ezxi5r 69 6 . . . cord-293714-s6ezxi5r 70 1 White white JJ cord-293714-s6ezxi5r 70 2 blood blood NN cord-293714-s6ezxi5r 70 3 cells cell NNS cord-293714-s6ezxi5r 70 4 / / SYM cord-293714-s6ezxi5r 70 5 high high JJ cord-293714-s6ezxi5r 70 6 - - HYPH cord-293714-s6ezxi5r 70 7 power power NN cord-293714-s6ezxi5r 70 8 field field NN cord-293714-s6ezxi5r 70 9 ! ! . cord-293714-s6ezxi5r 71 1 10 10 CD cord-293714-s6ezxi5r 71 2 in in IN cord-293714-s6ezxi5r 71 3 urinalysis urinalysis NN cord-293714-s6ezxi5r 71 4 Histopathological Histopathological NNP cord-293714-s6ezxi5r 71 5 data datum NNS cord-293714-s6ezxi5r 72 1 Some some DT cord-293714-s6ezxi5r 72 2 histological histological JJ cord-293714-s6ezxi5r 72 3 findings finding NNS cord-293714-s6ezxi5r 72 4 strongly strongly RB cord-293714-s6ezxi5r 72 5 suggest suggest VBP cord-293714-s6ezxi5r 72 6 that that IN cord-293714-s6ezxi5r 72 7 KS KS NNP cord-293714-s6ezxi5r 72 8 has have VBZ cord-293714-s6ezxi5r 72 9 an an DT cord-293714-s6ezxi5r 72 10 infectious infectious JJ cord-293714-s6ezxi5r 72 11 origin origin NN cord-293714-s6ezxi5r 72 12 , , , cord-293714-s6ezxi5r 72 13 although although IN cord-293714-s6ezxi5r 72 14 they -PRON- PRP cord-293714-s6ezxi5r 72 15 do do VBP cord-293714-s6ezxi5r 72 16 not not RB cord-293714-s6ezxi5r 72 17 identify identify VB cord-293714-s6ezxi5r 72 18 the the DT cord-293714-s6ezxi5r 72 19 responsible responsible JJ cord-293714-s6ezxi5r 72 20 pathogen pathogen NN cord-293714-s6ezxi5r 72 21 . . . cord-293714-s6ezxi5r 73 1 The the DT cord-293714-s6ezxi5r 73 2 most most RBS cord-293714-s6ezxi5r 73 3 important important JJ cord-293714-s6ezxi5r 73 4 is be VBZ cord-293714-s6ezxi5r 73 5 that that DT cord-293714-s6ezxi5r 73 6 persistent persistent JJ cord-293714-s6ezxi5r 73 7 intracytoplasmic intracytoplasmic JJ cord-293714-s6ezxi5r 73 8 inclusion inclusion NN cord-293714-s6ezxi5r 73 9 bodies body NNS cord-293714-s6ezxi5r 73 10 ( ( -LRB- cord-293714-s6ezxi5r 73 11 IIBs IIBs NNP cord-293714-s6ezxi5r 73 12 ) ) -RRB- cord-293714-s6ezxi5r 73 13 showing show VBG cord-293714-s6ezxi5r 73 14 amphophilic amphophilic JJ cord-293714-s6ezxi5r 73 15 staining stain VBG cord-293714-s6ezxi5r 73 16 by by IN cord-293714-s6ezxi5r 73 17 haematoxylin haematoxylin JJ cord-293714-s6ezxi5r 73 18 - - HYPH cord-293714-s6ezxi5r 73 19 eosin eosin NNS cord-293714-s6ezxi5r 73 20 and and CC cord-293714-s6ezxi5r 73 21 stain stain NN cord-293714-s6ezxi5r 73 22 for for IN cord-293714-s6ezxi5r 73 23 RNA RNA NNP cord-293714-s6ezxi5r 73 24 have have VBP cord-293714-s6ezxi5r 73 25 been be VBN cord-293714-s6ezxi5r 73 26 found find VBN cord-293714-s6ezxi5r 73 27 in in IN cord-293714-s6ezxi5r 73 28 most most JJS cord-293714-s6ezxi5r 73 29 of of IN cord-293714-s6ezxi5r 73 30 the the DT cord-293714-s6ezxi5r 73 31 tissues tissue NNS cord-293714-s6ezxi5r 73 32 of of IN cord-293714-s6ezxi5r 73 33 patients patient NNS cord-293714-s6ezxi5r 73 34 who who WP cord-293714-s6ezxi5r 73 35 have have VBP cord-293714-s6ezxi5r 73 36 died die VBN cord-293714-s6ezxi5r 73 37 because because IN cord-293714-s6ezxi5r 73 38 of of IN cord-293714-s6ezxi5r 73 39 KS KS NNP cord-293714-s6ezxi5r 73 40 . . . cord-293714-s6ezxi5r 74 1 33 33 CD cord-293714-s6ezxi5r 75 1 As as IN cord-293714-s6ezxi5r 75 2 transmission transmission NN cord-293714-s6ezxi5r 75 3 electron electron NN cord-293714-s6ezxi5r 75 4 microscopy microscopy NN cord-293714-s6ezxi5r 75 5 ( ( -LRB- cord-293714-s6ezxi5r 75 6 TEM TEM NNP cord-293714-s6ezxi5r 75 7 ) ) -RRB- cord-293714-s6ezxi5r 75 8 of of IN cord-293714-s6ezxi5r 75 9 bronchial bronchial JJ cord-293714-s6ezxi5r 75 10 epithelia epithelium NNS cord-293714-s6ezxi5r 75 11 has have VBZ cord-293714-s6ezxi5r 75 12 revealed reveal VBN cord-293714-s6ezxi5r 75 13 virus virus NN cord-293714-s6ezxi5r 75 14 - - HYPH cord-293714-s6ezxi5r 75 15 like like JJ cord-293714-s6ezxi5r 75 16 particles particle NNS cord-293714-s6ezxi5r 75 17 associated associate VBN cord-293714-s6ezxi5r 75 18 with with IN cord-293714-s6ezxi5r 75 19 the the DT cord-293714-s6ezxi5r 75 20 IIBs iibs NN cord-293714-s6ezxi5r 75 21 , , , cord-293714-s6ezxi5r 75 22 it -PRON- PRP cord-293714-s6ezxi5r 75 23 was be VBD cord-293714-s6ezxi5r 75 24 thought think VBN cord-293714-s6ezxi5r 75 25 that that IN cord-293714-s6ezxi5r 75 26 these these DT cord-293714-s6ezxi5r 75 27 may may MD cord-293714-s6ezxi5r 75 28 be be VB cord-293714-s6ezxi5r 75 29 a a DT cord-293714-s6ezxi5r 75 30 " " `` cord-293714-s6ezxi5r 75 31 footprint footprint NN cord-293714-s6ezxi5r 75 32 " " '' cord-293714-s6ezxi5r 75 33 of of IN cord-293714-s6ezxi5r 75 34 a a DT cord-293714-s6ezxi5r 75 35 viral viral JJ cord-293714-s6ezxi5r 75 36 infection infection NN cord-293714-s6ezxi5r 75 37 that that WDT cord-293714-s6ezxi5r 75 38 may may MD cord-293714-s6ezxi5r 75 39 persist persist VB cord-293714-s6ezxi5r 75 40 indefinitely indefinitely RB cord-293714-s6ezxi5r 75 41 : : : cord-293714-s6ezxi5r 75 42 Rowley Rowley NNP cord-293714-s6ezxi5r 75 43 et et NNP cord-293714-s6ezxi5r 75 44 al al NNP cord-293714-s6ezxi5r 75 45 . . NNP cord-293714-s6ezxi5r 75 46 speculated speculate VBD cord-293714-s6ezxi5r 75 47 that that IN cord-293714-s6ezxi5r 75 48 the the DT cord-293714-s6ezxi5r 75 49 infection infection NN cord-293714-s6ezxi5r 75 50 associated associate VBN cord-293714-s6ezxi5r 75 51 with with IN cord-293714-s6ezxi5r 75 52 the the DT cord-293714-s6ezxi5r 75 53 development development NN cord-293714-s6ezxi5r 75 54 of of IN cord-293714-s6ezxi5r 75 55 KS KS NNP cord-293714-s6ezxi5r 75 56 could could MD cord-293714-s6ezxi5r 75 57 be be VB cord-293714-s6ezxi5r 75 58 due due JJ cord-293714-s6ezxi5r 75 59 to to IN cord-293714-s6ezxi5r 75 60 a a DT cord-293714-s6ezxi5r 75 61 new new JJ cord-293714-s6ezxi5r 75 62 and and CC cord-293714-s6ezxi5r 75 63 ubiquitous ubiquitous JJ cord-293714-s6ezxi5r 75 64 RNA RNA NNP cord-293714-s6ezxi5r 75 65 virus virus NN cord-293714-s6ezxi5r 75 66 that that WDT cord-293714-s6ezxi5r 75 67 caused cause VBD cord-293714-s6ezxi5r 75 68 only only RB cord-293714-s6ezxi5r 75 69 asymptomatic asymptomatic JJ cord-293714-s6ezxi5r 75 70 infection infection NN cord-293714-s6ezxi5r 75 71 or or CC cord-293714-s6ezxi5r 75 72 very very RB cord-293714-s6ezxi5r 75 73 mild mild JJ cord-293714-s6ezxi5r 75 74 disease disease NN cord-293714-s6ezxi5r 75 75 in in IN cord-293714-s6ezxi5r 75 76 the the DT cord-293714-s6ezxi5r 75 77 general general JJ cord-293714-s6ezxi5r 75 78 population population NN cord-293714-s6ezxi5r 75 79 , , , cord-293714-s6ezxi5r 75 80 but but CC cord-293714-s6ezxi5r 75 81 KS KS NNP cord-293714-s6ezxi5r 75 82 in in IN cord-293714-s6ezxi5r 75 83 genetically genetically RB cord-293714-s6ezxi5r 75 84 selected select VBN cord-293714-s6ezxi5r 75 85 subjects subject NNS cord-293714-s6ezxi5r 75 86 . . . cord-293714-s6ezxi5r 76 1 34 34 CD cord-293714-s6ezxi5r 77 1 It -PRON- PRP cord-293714-s6ezxi5r 77 2 was be VBD cord-293714-s6ezxi5r 77 3 thought think VBN cord-293714-s6ezxi5r 77 4 that that IN cord-293714-s6ezxi5r 77 5 the the DT cord-293714-s6ezxi5r 77 6 first first JJ cord-293714-s6ezxi5r 77 7 site site NN cord-293714-s6ezxi5r 77 8 of of IN cord-293714-s6ezxi5r 77 9 infection infection NN cord-293714-s6ezxi5r 77 10 was be VBD cord-293714-s6ezxi5r 77 11 the the DT cord-293714-s6ezxi5r 77 12 respiratory respiratory JJ cord-293714-s6ezxi5r 77 13 tract tract NN cord-293714-s6ezxi5r 77 14 , , , cord-293714-s6ezxi5r 77 15 with with IN cord-293714-s6ezxi5r 77 16 further further JJ cord-293714-s6ezxi5r 77 17 dissemination dissemination NN cord-293714-s6ezxi5r 77 18 through through IN cord-293714-s6ezxi5r 77 19 macrophages macrophage NNS cord-293714-s6ezxi5r 77 20 to to IN cord-293714-s6ezxi5r 77 21 all all DT cord-293714-s6ezxi5r 77 22 body body NN cord-293714-s6ezxi5r 77 23 sites site NNS cord-293714-s6ezxi5r 77 24 , , , cord-293714-s6ezxi5r 77 25 including include VBG cord-293714-s6ezxi5r 77 26 the the DT cord-293714-s6ezxi5r 77 27 medium medium JJ cord-293714-s6ezxi5r 77 28 - - HYPH cord-293714-s6ezxi5r 77 29 sized sized JJ cord-293714-s6ezxi5r 77 30 arteries artery NNS cord-293714-s6ezxi5r 77 31 ( ( -LRB- cord-293714-s6ezxi5r 77 32 mainly mainly RB cord-293714-s6ezxi5r 77 33 the the DT cord-293714-s6ezxi5r 77 34 coronary coronary JJ cord-293714-s6ezxi5r 77 35 arteries artery NNS cord-293714-s6ezxi5r 77 36 ) ) -RRB- cord-293714-s6ezxi5r 77 37 that that WDT cord-293714-s6ezxi5r 77 38 are be VBP cord-293714-s6ezxi5r 77 39 the the DT cord-293714-s6ezxi5r 77 40 most most RBS cord-293714-s6ezxi5r 77 41 crucial crucial JJ cord-293714-s6ezxi5r 77 42 targets target NNS cord-293714-s6ezxi5r 77 43 in in IN cord-293714-s6ezxi5r 77 44 KS KS NNP cord-293714-s6ezxi5r 77 45 . . . cord-293714-s6ezxi5r 78 1 Further further JJ cord-293714-s6ezxi5r 78 2 findings finding NNS cord-293714-s6ezxi5r 78 3 that that WDT cord-293714-s6ezxi5r 78 4 strongly strongly RB cord-293714-s6ezxi5r 78 5 support support VBP cord-293714-s6ezxi5r 78 6 an an DT cord-293714-s6ezxi5r 78 7 infectious infectious JJ cord-293714-s6ezxi5r 78 8 origin origin NN cord-293714-s6ezxi5r 78 9 of of IN cord-293714-s6ezxi5r 78 10 KS KS NNP cord-293714-s6ezxi5r 78 11 are be VBP cord-293714-s6ezxi5r 78 12 those those DT cord-293714-s6ezxi5r 78 13 of of IN cord-293714-s6ezxi5r 78 14 Orenstein Orenstein NNP cord-293714-s6ezxi5r 78 15 et et NNP cord-293714-s6ezxi5r 78 16 al al NNP cord-293714-s6ezxi5r 78 17 . . NNP cord-293714-s6ezxi5r 78 18 , , , cord-293714-s6ezxi5r 78 19 who who WP cord-293714-s6ezxi5r 78 20 used use VBD cord-293714-s6ezxi5r 78 21 light light JJ cord-293714-s6ezxi5r 78 22 microscopy microscopy NNS cord-293714-s6ezxi5r 78 23 and and CC cord-293714-s6ezxi5r 78 24 TEM tem NN cord-293714-s6ezxi5r 78 25 to to TO cord-293714-s6ezxi5r 78 26 study study VB cord-293714-s6ezxi5r 78 27 tissue tissue NN cord-293714-s6ezxi5r 78 28 specimens specimen NNS cord-293714-s6ezxi5r 78 29 from from IN cord-293714-s6ezxi5r 78 30 32 32 CD cord-293714-s6ezxi5r 78 31 autopsies autopsy NNS cord-293714-s6ezxi5r 78 32 , , , cord-293714-s6ezxi5r 78 33 eight eight CD cord-293714-s6ezxi5r 78 34 heart heart NN cord-293714-s6ezxi5r 78 35 transplants transplant NNS cord-293714-s6ezxi5r 78 36 and and CC cord-293714-s6ezxi5r 78 37 an an DT cord-293714-s6ezxi5r 78 38 excised excise VBN cord-293714-s6ezxi5r 78 39 coronary coronary JJ cord-293714-s6ezxi5r 78 40 aneurysm aneurysm NN cord-293714-s6ezxi5r 78 41 of of IN cord-293714-s6ezxi5r 78 42 patients patient NNS cord-293714-s6ezxi5r 78 43 with with IN cord-293714-s6ezxi5r 78 44 KS KS NNP cord-293714-s6ezxi5r 78 45 and and CC cord-293714-s6ezxi5r 78 46 identified identify VBD cord-293714-s6ezxi5r 78 47 three three CD cord-293714-s6ezxi5r 78 48 different different JJ cord-293714-s6ezxi5r 78 49 vasculopathic vasculopathic JJ cord-293714-s6ezxi5r 78 50 processes process NNS cord-293714-s6ezxi5r 78 51 : : : cord-293714-s6ezxi5r 78 52 acute acute JJ cord-293714-s6ezxi5r 78 53 self self NN cord-293714-s6ezxi5r 78 54 - - HYPH cord-293714-s6ezxi5r 78 55 limited limit VBN cord-293714-s6ezxi5r 78 56 necrotising necrotise VBG cord-293714-s6ezxi5r 78 57 arteritis arteritis NN cord-293714-s6ezxi5r 78 58 ( ( -LRB- cord-293714-s6ezxi5r 78 59 NA NA NNP cord-293714-s6ezxi5r 78 60 ) ) -RRB- cord-293714-s6ezxi5r 78 61 , , , cord-293714-s6ezxi5r 78 62 subacute subacute JJ cord-293714-s6ezxi5r 78 63 / / SYM cord-293714-s6ezxi5r 78 64 chronic chronic JJ cord-293714-s6ezxi5r 78 65 vasculitis vasculitis NN cord-293714-s6ezxi5r 78 66 , , , cord-293714-s6ezxi5r 78 67 and and CC cord-293714-s6ezxi5r 78 68 luminal luminal JJ cord-293714-s6ezxi5r 78 69 myofibroplastic myofibroplastic JJ cord-293714-s6ezxi5r 78 70 proliferation proliferation NN cord-293714-s6ezxi5r 78 71 . . . cord-293714-s6ezxi5r 79 1 On on IN cord-293714-s6ezxi5r 79 2 the the DT cord-293714-s6ezxi5r 79 3 basis basis NN cord-293714-s6ezxi5r 79 4 of of IN cord-293714-s6ezxi5r 79 5 the the DT cord-293714-s6ezxi5r 79 6 changes change NNS cord-293714-s6ezxi5r 79 7 in in IN cord-293714-s6ezxi5r 79 8 coronary coronary JJ cord-293714-s6ezxi5r 79 9 and and CC cord-293714-s6ezxi5r 79 10 non non JJ cord-293714-s6ezxi5r 79 11 - - JJ cord-293714-s6ezxi5r 79 12 coronary coronary JJ cord-293714-s6ezxi5r 79 13 arteries artery NNS cord-293714-s6ezxi5r 79 14 during during IN cord-293714-s6ezxi5r 79 15 the the DT cord-293714-s6ezxi5r 79 16 different different JJ cord-293714-s6ezxi5r 79 17 phases phase NNS cord-293714-s6ezxi5r 79 18 of of IN cord-293714-s6ezxi5r 79 19 KS KS NNP cord-293714-s6ezxi5r 79 20 , , , cord-293714-s6ezxi5r 79 21 they -PRON- PRP cord-293714-s6ezxi5r 79 22 considered consider VBD cord-293714-s6ezxi5r 79 23 NA NA NNP cord-293714-s6ezxi5r 79 24 the the DT cord-293714-s6ezxi5r 79 25 only only JJ cord-293714-s6ezxi5r 79 26 self self NN cord-293714-s6ezxi5r 79 27 - - HYPH cord-293714-s6ezxi5r 79 28 limiting limit VBG cord-293714-s6ezxi5r 79 29 process process NN cord-293714-s6ezxi5r 79 30 of of IN cord-293714-s6ezxi5r 79 31 the the DT cord-293714-s6ezxi5r 79 32 three three CD cord-293714-s6ezxi5r 79 33 , , , cord-293714-s6ezxi5r 79 34 and and CC cord-293714-s6ezxi5r 79 35 that that IN cord-293714-s6ezxi5r 79 36 it -PRON- PRP cord-293714-s6ezxi5r 79 37 was be VBD cord-293714-s6ezxi5r 79 38 consistent consistent JJ cord-293714-s6ezxi5r 79 39 with with IN cord-293714-s6ezxi5r 79 40 an an DT cord-293714-s6ezxi5r 79 41 acute acute JJ cord-293714-s6ezxi5r 79 42 viral viral JJ cord-293714-s6ezxi5r 79 43 infection infection NN cord-293714-s6ezxi5r 79 44 . . . cord-293714-s6ezxi5r 80 1 35 35 CD cord-293714-s6ezxi5r 80 2 _SP cord-293714-s6ezxi5r 81 1 Many many JJ cord-293714-s6ezxi5r 81 2 epidemiological epidemiological JJ cord-293714-s6ezxi5r 81 3 findings finding NNS cord-293714-s6ezxi5r 81 4 regarding regard VBG cord-293714-s6ezxi5r 81 5 KS KS NNP cord-293714-s6ezxi5r 81 6 are be VBP cord-293714-s6ezxi5r 81 7 consistent consistent JJ cord-293714-s6ezxi5r 81 8 with with IN cord-293714-s6ezxi5r 81 9 an an DT cord-293714-s6ezxi5r 81 10 infectious infectious JJ cord-293714-s6ezxi5r 81 11 origin origin NN cord-293714-s6ezxi5r 81 12 , , , cord-293714-s6ezxi5r 81 13 as as IN cord-293714-s6ezxi5r 81 14 they -PRON- PRP cord-293714-s6ezxi5r 81 15 are be VBP cord-293714-s6ezxi5r 81 16 quite quite RB cord-293714-s6ezxi5r 81 17 similar similar JJ cord-293714-s6ezxi5r 81 18 to to IN cord-293714-s6ezxi5r 81 19 those those DT cord-293714-s6ezxi5r 81 20 of of IN cord-293714-s6ezxi5r 81 21 various various JJ cord-293714-s6ezxi5r 81 22 infectious infectious JJ cord-293714-s6ezxi5r 81 23 diseases disease NNS cord-293714-s6ezxi5r 81 24 . . . cord-293714-s6ezxi5r 82 1 First first RB cord-293714-s6ezxi5r 82 2 of of IN cord-293714-s6ezxi5r 82 3 all all DT cord-293714-s6ezxi5r 82 4 , , , cord-293714-s6ezxi5r 82 5 there there EX cord-293714-s6ezxi5r 82 6 is be VBZ cord-293714-s6ezxi5r 82 7 the the DT cord-293714-s6ezxi5r 82 8 occurrence occurrence NN cord-293714-s6ezxi5r 82 9 of of IN cord-293714-s6ezxi5r 82 10 epidemics epidemic NNS cord-293714-s6ezxi5r 82 11 because because IN cord-293714-s6ezxi5r 82 12 , , , cord-293714-s6ezxi5r 82 13 although although IN cord-293714-s6ezxi5r 82 14 cases case NNS cord-293714-s6ezxi5r 82 15 of of IN cord-293714-s6ezxi5r 82 16 KS KS NNP cord-293714-s6ezxi5r 82 17 are be VBP cord-293714-s6ezxi5r 82 18 diagnosed diagnose VBN cord-293714-s6ezxi5r 82 19 , , , cord-293714-s6ezxi5r 82 20 there there EX cord-293714-s6ezxi5r 82 21 are be VBP cord-293714-s6ezxi5r 82 22 also also RB cord-293714-s6ezxi5r 82 23 sometimes sometimes RB cord-293714-s6ezxi5r 82 24 widespread widespread JJ cord-293714-s6ezxi5r 82 25 epidemics epidemic NNS cord-293714-s6ezxi5r 82 26 . . . cord-293714-s6ezxi5r 83 1 In in IN cord-293714-s6ezxi5r 83 2 Japan Japan NNP cord-293714-s6ezxi5r 83 3 , , , cord-293714-s6ezxi5r 83 4 where where WRB cord-293714-s6ezxi5r 83 5 nationwide nationwide JJ cord-293714-s6ezxi5r 83 6 epidemiological epidemiological JJ cord-293714-s6ezxi5r 83 7 surveys survey NNS cord-293714-s6ezxi5r 83 8 of of IN cord-293714-s6ezxi5r 83 9 KS KS NNP cord-293714-s6ezxi5r 83 10 have have VBP cord-293714-s6ezxi5r 83 11 been be VBN cord-293714-s6ezxi5r 83 12 carried carry VBN cord-293714-s6ezxi5r 83 13 out out RP cord-293714-s6ezxi5r 83 14 almost almost RB cord-293714-s6ezxi5r 83 15 every every DT cord-293714-s6ezxi5r 83 16 two two CD cord-293714-s6ezxi5r 83 17 years year NNS cord-293714-s6ezxi5r 83 18 since since IN cord-293714-s6ezxi5r 83 19 1970 1970 CD cord-293714-s6ezxi5r 83 20 , , , cord-293714-s6ezxi5r 83 21 36 36 CD cord-293714-s6ezxi5r 83 22 three three CD cord-293714-s6ezxi5r 83 23 large large JJ cord-293714-s6ezxi5r 83 24 - - HYPH cord-293714-s6ezxi5r 83 25 scale scale NN cord-293714-s6ezxi5r 83 26 epidemics epidemic NNS cord-293714-s6ezxi5r 83 27 were be VBD cord-293714-s6ezxi5r 83 28 recorded record VBN cord-293714-s6ezxi5r 83 29 in in IN cord-293714-s6ezxi5r 83 30 1979 1979 CD cord-293714-s6ezxi5r 83 31 , , , cord-293714-s6ezxi5r 83 32 1982 1982 CD cord-293714-s6ezxi5r 83 33 , , , cord-293714-s6ezxi5r 83 34 and and CC cord-293714-s6ezxi5r 83 35 1986 1986 CD cord-293714-s6ezxi5r 83 36 , , , cord-293714-s6ezxi5r 83 37 with with IN cord-293714-s6ezxi5r 83 38 incidence incidence NN cord-293714-s6ezxi5r 83 39 rates rate NNS cord-293714-s6ezxi5r 83 40 that that WDT cord-293714-s6ezxi5r 83 41 were be VBD cord-293714-s6ezxi5r 83 42 several several JJ cord-293714-s6ezxi5r 83 43 times time NNS cord-293714-s6ezxi5r 83 44 higher high JJR cord-293714-s6ezxi5r 83 45 than than IN cord-293714-s6ezxi5r 83 46 those those DT cord-293714-s6ezxi5r 83 47 reported report VBN cord-293714-s6ezxi5r 83 48 in in IN cord-293714-s6ezxi5r 83 49 the the DT cord-293714-s6ezxi5r 83 50 previous previous JJ cord-293714-s6ezxi5r 83 51 and and CC cord-293714-s6ezxi5r 83 52 following follow VBG cord-293714-s6ezxi5r 83 53 year year NN cord-293714-s6ezxi5r 83 54 . . . cord-293714-s6ezxi5r 84 1 Secondly secondly RB cord-293714-s6ezxi5r 84 2 , , , cord-293714-s6ezxi5r 84 3 as as IN cord-293714-s6ezxi5r 84 4 in in IN cord-293714-s6ezxi5r 84 5 the the DT cord-293714-s6ezxi5r 84 6 case case NN cord-293714-s6ezxi5r 84 7 of of IN cord-293714-s6ezxi5r 84 8 a a DT cord-293714-s6ezxi5r 84 9 number number NN cord-293714-s6ezxi5r 84 10 of of IN cord-293714-s6ezxi5r 84 11 infectious infectious JJ cord-293714-s6ezxi5r 84 12 diseases disease NNS cord-293714-s6ezxi5r 84 13 , , , cord-293714-s6ezxi5r 84 14 37 37 CD cord-293714-s6ezxi5r 84 15 , , , cord-293714-s6ezxi5r 84 16 38 38 CD cord-293714-s6ezxi5r 84 17 KS KS NNP cord-293714-s6ezxi5r 84 18 is be VBZ cord-293714-s6ezxi5r 84 19 more more RBR cord-293714-s6ezxi5r 84 20 frequent frequent JJ cord-293714-s6ezxi5r 84 21 in in IN cord-293714-s6ezxi5r 84 22 boys boy NNS cord-293714-s6ezxi5r 84 23 , , , cord-293714-s6ezxi5r 84 24 and and CC cord-293714-s6ezxi5r 84 25 the the DT cord-293714-s6ezxi5r 84 26 male male NN cord-293714-s6ezxi5r 84 27 to to IN cord-293714-s6ezxi5r 84 28 female female JJ cord-293714-s6ezxi5r 84 29 ratio ratio NN cord-293714-s6ezxi5r 84 30 is be VBZ cord-293714-s6ezxi5r 84 31 about about IN cord-293714-s6ezxi5r 84 32 1.6 1.6 CD cord-293714-s6ezxi5r 84 33 . . . cord-293714-s6ezxi5r 85 1 39 39 CD cord-293714-s6ezxi5r 85 2 Thirdly thirdly RB cord-293714-s6ezxi5r 85 3 ( ( -LRB- cord-293714-s6ezxi5r 85 4 once once RB cord-293714-s6ezxi5r 85 5 again again RB cord-293714-s6ezxi5r 85 6 as as IN cord-293714-s6ezxi5r 85 7 in in IN cord-293714-s6ezxi5r 85 8 the the DT cord-293714-s6ezxi5r 85 9 case case NN cord-293714-s6ezxi5r 85 10 of of IN cord-293714-s6ezxi5r 85 11 many many JJ cord-293714-s6ezxi5r 85 12 infectious infectious JJ cord-293714-s6ezxi5r 85 13 diseases disease NNS cord-293714-s6ezxi5r 85 14 ) ) -RRB- cord-293714-s6ezxi5r 85 15 , , , cord-293714-s6ezxi5r 85 16 the the DT cord-293714-s6ezxi5r 85 17 incidence incidence NN cord-293714-s6ezxi5r 85 18 of of IN cord-293714-s6ezxi5r 85 19 KS KS NNP cord-293714-s6ezxi5r 85 20 seems seem VBZ cord-293714-s6ezxi5r 85 21 to to TO cord-293714-s6ezxi5r 85 22 be be VB cord-293714-s6ezxi5r 85 23 closely closely RB cord-293714-s6ezxi5r 85 24 related relate VBN cord-293714-s6ezxi5r 85 25 to to IN cord-293714-s6ezxi5r 85 26 weather weather NN cord-293714-s6ezxi5r 85 27 conditions condition NNS cord-293714-s6ezxi5r 85 28 , , , cord-293714-s6ezxi5r 85 29 although although IN cord-293714-s6ezxi5r 85 30 the the DT cord-293714-s6ezxi5r 85 31 predominant predominant JJ cord-293714-s6ezxi5r 85 32 season season NN cord-293714-s6ezxi5r 85 33 varies vary VBZ cord-293714-s6ezxi5r 85 34 from from IN cord-293714-s6ezxi5r 85 35 country country NN cord-293714-s6ezxi5r 85 36 to to IN cord-293714-s6ezxi5r 85 37 country country NN cord-293714-s6ezxi5r 85 38 : : : cord-293714-s6ezxi5r 85 39 winter winter NN cord-293714-s6ezxi5r 85 40 and and CC cord-293714-s6ezxi5r 85 41 spring spring NN cord-293714-s6ezxi5r 85 42 in in IN cord-293714-s6ezxi5r 85 43 the the DT cord-293714-s6ezxi5r 85 44 United United NNP cord-293714-s6ezxi5r 85 45 Kingdom Kingdom NNP cord-293714-s6ezxi5r 85 46 , , , cord-293714-s6ezxi5r 85 47 Australia Australia NNP cord-293714-s6ezxi5r 85 48 and and CC cord-293714-s6ezxi5r 85 49 the the DT cord-293714-s6ezxi5r 85 50 USA USA NNP cord-293714-s6ezxi5r 85 51 , , , cord-293714-s6ezxi5r 85 52 and and CC cord-293714-s6ezxi5r 85 53 spring spring NN cord-293714-s6ezxi5r 85 54 and and CC cord-293714-s6ezxi5r 85 55 summer summer NN cord-293714-s6ezxi5r 85 56 in in IN cord-293714-s6ezxi5r 85 57 China China NNP cord-293714-s6ezxi5r 85 58 . . . cord-293714-s6ezxi5r 86 1 40e43 40e43 CD cord-293714-s6ezxi5r 86 2 Pitzer Pitzer NNP cord-293714-s6ezxi5r 86 3 et et NNP cord-293714-s6ezxi5r 86 4 al al NNP cord-293714-s6ezxi5r 86 5 . . . cord-293714-s6ezxi5r 87 1 , , , cord-293714-s6ezxi5r 87 2 examined examine VBD cord-293714-s6ezxi5r 87 3 seasonal seasonal JJ cord-293714-s6ezxi5r 87 4 changes change NNS cord-293714-s6ezxi5r 87 5 in in IN cord-293714-s6ezxi5r 87 6 the the DT cord-293714-s6ezxi5r 87 7 age age NN cord-293714-s6ezxi5r 87 8 and and CC cord-293714-s6ezxi5r 87 9 incidence incidence NN cord-293714-s6ezxi5r 87 10 of of IN cord-293714-s6ezxi5r 87 11 KS KS NNP cord-293714-s6ezxi5r 87 12 hospitalisations hospitalisation NNS cord-293714-s6ezxi5r 87 13 in in IN cord-293714-s6ezxi5r 87 14 the the DT cord-293714-s6ezxi5r 87 15 USA USA NNP cord-293714-s6ezxi5r 87 16 , , , cord-293714-s6ezxi5r 87 17 and and CC cord-293714-s6ezxi5r 87 18 found find VBD cord-293714-s6ezxi5r 87 19 that that IN cord-293714-s6ezxi5r 87 20 periods period NNS cord-293714-s6ezxi5r 87 21 of of IN cord-293714-s6ezxi5r 87 22 high high JJ cord-293714-s6ezxi5r 87 23 incidence incidence NN cord-293714-s6ezxi5r 87 24 corresponded correspond VBD cord-293714-s6ezxi5r 87 25 to to IN cord-293714-s6ezxi5r 87 26 a a DT cord-293714-s6ezxi5r 87 27 low low JJ cord-293714-s6ezxi5r 87 28 average average JJ cord-293714-s6ezxi5r 87 29 age age NN cord-293714-s6ezxi5r 87 30 , , , cord-293714-s6ezxi5r 87 31 and and CC cord-293714-s6ezxi5r 87 32 vice vice NN cord-293714-s6ezxi5r 87 33 versa versa RB cord-293714-s6ezxi5r 87 34 . . . cord-293714-s6ezxi5r 88 1 40 40 CD cord-293714-s6ezxi5r 88 2 Comparison comparison NN cord-293714-s6ezxi5r 88 3 of of IN cord-293714-s6ezxi5r 88 4 the the DT cord-293714-s6ezxi5r 88 5 observed observed JJ cord-293714-s6ezxi5r 88 6 pattern pattern NN cord-293714-s6ezxi5r 88 7 with with IN cord-293714-s6ezxi5r 88 8 those those DT cord-293714-s6ezxi5r 88 9 predicted predict VBN cord-293714-s6ezxi5r 88 10 by by IN cord-293714-s6ezxi5r 88 11 a a DT cord-293714-s6ezxi5r 88 12 suite suite NN cord-293714-s6ezxi5r 88 13 of of IN cord-293714-s6ezxi5r 88 14 models model NNS cord-293714-s6ezxi5r 88 15 based base VBN cord-293714-s6ezxi5r 88 16 on on IN cord-293714-s6ezxi5r 88 17 different different JJ cord-293714-s6ezxi5r 88 18 etiological etiological JJ cord-293714-s6ezxi5r 88 19 hypotheses hypothesis NNS cord-293714-s6ezxi5r 88 20 , , , cord-293714-s6ezxi5r 88 21 the the DT cord-293714-s6ezxi5r 88 22 ageincidence ageincidence NN cord-293714-s6ezxi5r 88 23 pattern pattern NN cord-293714-s6ezxi5r 88 24 of of IN cord-293714-s6ezxi5r 88 25 KS KS NNP cord-293714-s6ezxi5r 88 26 suggested suggest VBD cord-293714-s6ezxi5r 88 27 the the DT cord-293714-s6ezxi5r 88 28 involvement involvement NN cord-293714-s6ezxi5r 88 29 of of IN cord-293714-s6ezxi5r 88 30 an an DT cord-293714-s6ezxi5r 88 31 imperfectly imperfectly RB cord-293714-s6ezxi5r 88 32 immunising immunise VBG cord-293714-s6ezxi5r 88 33 infection infection NN cord-293714-s6ezxi5r 88 34 and/or and/or CC cord-293714-s6ezxi5r 88 35 a a DT cord-293714-s6ezxi5r 88 36 persistently persistently RB cord-293714-s6ezxi5r 88 37 infectious infectious JJ cord-293714-s6ezxi5r 88 38 agent agent NN cord-293714-s6ezxi5r 88 39 . . . cord-293714-s6ezxi5r 89 1 The the DT cord-293714-s6ezxi5r 89 2 possible possible JJ cord-293714-s6ezxi5r 89 3 relationship relationship NN cord-293714-s6ezxi5r 89 4 between between IN cord-293714-s6ezxi5r 89 5 seasonal seasonal JJ cord-293714-s6ezxi5r 89 6 variations variation NNS cord-293714-s6ezxi5r 89 7 in in IN cord-293714-s6ezxi5r 89 8 the the DT cord-293714-s6ezxi5r 89 9 incidence incidence NN cord-293714-s6ezxi5r 89 10 of of IN cord-293714-s6ezxi5r 89 11 KS KS NNP cord-293714-s6ezxi5r 89 12 and and CC cord-293714-s6ezxi5r 89 13 an an DT cord-293714-s6ezxi5r 89 14 infectious infectious JJ cord-293714-s6ezxi5r 89 15 aetiology aetiology NN cord-293714-s6ezxi5r 89 16 is be VBZ cord-293714-s6ezxi5r 89 17 also also RB cord-293714-s6ezxi5r 89 18 supported support VBN cord-293714-s6ezxi5r 89 19 by by IN cord-293714-s6ezxi5r 89 20 data datum NNS cord-293714-s6ezxi5r 89 21 showing show VBG cord-293714-s6ezxi5r 89 22 that that IN cord-293714-s6ezxi5r 89 23 its -PRON- PRP$ cord-293714-s6ezxi5r 89 24 incidence incidence NN cord-293714-s6ezxi5r 89 25 in in IN cord-293714-s6ezxi5r 89 26 the the DT cord-293714-s6ezxi5r 89 27 USA USA NNP cord-293714-s6ezxi5r 89 28 inversely inversely RB cord-293714-s6ezxi5r 89 29 correlates correlate VBZ cord-293714-s6ezxi5r 89 30 with with IN cord-293714-s6ezxi5r 89 31 average average JJ cord-293714-s6ezxi5r 89 32 monthly monthly JJ cord-293714-s6ezxi5r 89 33 temperature temperature NN cord-293714-s6ezxi5r 89 34 ( ( -LRB- cord-293714-s6ezxi5r 89 35 r r NN cord-293714-s6ezxi5r 89 36 Z Z NNP cord-293714-s6ezxi5r 89 37 À0.47 À0.47 NNP cord-293714-s6ezxi5r 89 38 ; ; : cord-293714-s6ezxi5r 89 39 p p NN cord-293714-s6ezxi5r 89 40 < < XX cord-293714-s6ezxi5r 89 41 0.001 0.001 CD cord-293714-s6ezxi5r 89 42 ) ) -RRB- cord-293714-s6ezxi5r 89 43 and and CC cord-293714-s6ezxi5r 89 44 positively positively RB cord-293714-s6ezxi5r 89 45 correlates correlate VBZ cord-293714-s6ezxi5r 89 46 with with IN cord-293714-s6ezxi5r 89 47 The the DT cord-293714-s6ezxi5r 89 48 role role NN cord-293714-s6ezxi5r 89 49 of of IN cord-293714-s6ezxi5r 89 50 infection infection NN cord-293714-s6ezxi5r 89 51 in in IN cord-293714-s6ezxi5r 89 52 KS KS NNP cord-293714-s6ezxi5r 90 1 average average JJ cord-293714-s6ezxi5r 90 2 monthly monthly JJ cord-293714-s6ezxi5r 90 3 precipitation precipitation NN cord-293714-s6ezxi5r 90 4 ( ( -LRB- cord-293714-s6ezxi5r 90 5 r r NN cord-293714-s6ezxi5r 90 6 Z Z NNP cord-293714-s6ezxi5r 90 7 À0.52 À0.52 NNP cord-293714-s6ezxi5r 90 8 ; ; : cord-293714-s6ezxi5r 90 9 p p NN cord-293714-s6ezxi5r 90 10 < < XX cord-293714-s6ezxi5r 90 11 0.001 0.001 CD cord-293714-s6ezxi5r 90 12 ) ) -RRB- cord-293714-s6ezxi5r 90 13 . . . cord-293714-s6ezxi5r 91 1 41 41 CD cord-293714-s6ezxi5r 92 1 Moreover moreover RB cord-293714-s6ezxi5r 92 2 , , , cord-293714-s6ezxi5r 92 3 analyses analysis NNS cord-293714-s6ezxi5r 92 4 of of IN cord-293714-s6ezxi5r 92 5 the the DT cord-293714-s6ezxi5r 92 6 three three CD cord-293714-s6ezxi5r 92 7 major major JJ cord-293714-s6ezxi5r 92 8 KS KS NNP cord-293714-s6ezxi5r 92 9 epidemics epidemic NNS cord-293714-s6ezxi5r 92 10 in in IN cord-293714-s6ezxi5r 92 11 Japan Japan NNP cord-293714-s6ezxi5r 92 12 , , , cord-293714-s6ezxi5r 92 13 major major JJ cord-293714-s6ezxi5r 92 14 non non JJ cord-293714-s6ezxi5r 92 15 - - JJ cord-293714-s6ezxi5r 92 16 epidemic epidemic JJ cord-293714-s6ezxi5r 92 17 inter inter JJ cord-293714-s6ezxi5r 92 18 - - JJ cord-293714-s6ezxi5r 92 19 annual annual JJ cord-293714-s6ezxi5r 92 20 fluctuations fluctuation NNS cord-293714-s6ezxi5r 92 21 of of IN cord-293714-s6ezxi5r 92 22 KS KS NNP cord-293714-s6ezxi5r 92 23 cases case NNS cord-293714-s6ezxi5r 92 24 in in IN cord-293714-s6ezxi5r 92 25 Japan Japan NNP cord-293714-s6ezxi5r 92 26 and and CC cord-293714-s6ezxi5r 92 27 San San NNP cord-293714-s6ezxi5r 92 28 Diego Diego NNP cord-293714-s6ezxi5r 92 29 , , , cord-293714-s6ezxi5r 92 30 and and CC cord-293714-s6ezxi5r 92 31 seasonal seasonal JJ cord-293714-s6ezxi5r 92 32 variations variation NNS cord-293714-s6ezxi5r 92 33 in in IN cord-293714-s6ezxi5r 92 34 the the DT cord-293714-s6ezxi5r 92 35 incidence incidence NN cord-293714-s6ezxi5r 92 36 of of IN cord-293714-s6ezxi5r 92 37 KS KS NNP cord-293714-s6ezxi5r 92 38 in in IN cord-293714-s6ezxi5r 92 39 Japan Japan NNP cord-293714-s6ezxi5r 92 40 , , , cord-293714-s6ezxi5r 92 41 Hawaii Hawaii NNP cord-293714-s6ezxi5r 92 42 and and CC cord-293714-s6ezxi5r 92 43 San San NNP cord-293714-s6ezxi5r 92 44 Diego Diego NNP cord-293714-s6ezxi5r 92 45 have have VBP cord-293714-s6ezxi5r 92 46 revealed reveal VBN cord-293714-s6ezxi5r 92 47 a a DT cord-293714-s6ezxi5r 92 48 consistent consistent JJ cord-293714-s6ezxi5r 92 49 pattern pattern NN cord-293714-s6ezxi5r 92 50 linking link VBG cord-293714-s6ezxi5r 92 51 KS KS NNP cord-293714-s6ezxi5r 92 52 cases case NNS cord-293714-s6ezxi5r 92 53 to to IN cord-293714-s6ezxi5r 92 54 large large JJ cord-293714-s6ezxi5r 92 55 - - HYPH cord-293714-s6ezxi5r 92 56 scale scale NN cord-293714-s6ezxi5r 92 57 wind wind NN cord-293714-s6ezxi5r 92 58 currents current NNS cord-293714-s6ezxi5r 92 59 originating originate VBG cord-293714-s6ezxi5r 92 60 in in IN cord-293714-s6ezxi5r 92 61 central central JJ cord-293714-s6ezxi5r 92 62 Asia Asia NNP cord-293714-s6ezxi5r 92 63 and and CC cord-293714-s6ezxi5r 92 64 crossing cross VBG cord-293714-s6ezxi5r 92 65 the the DT cord-293714-s6ezxi5r 92 66 North North NNP cord-293714-s6ezxi5r 92 67 Pacific Pacific NNP cord-293714-s6ezxi5r 92 68 . . . cord-293714-s6ezxi5r 93 1 42 42 CD cord-293714-s6ezxi5r 94 1 This this DT cord-293714-s6ezxi5r 94 2 seems seem VBZ cord-293714-s6ezxi5r 94 3 to to TO cord-293714-s6ezxi5r 94 4 indicate indicate VB cord-293714-s6ezxi5r 94 5 that that IN cord-293714-s6ezxi5r 94 6 the the DT cord-293714-s6ezxi5r 94 7 environmental environmental JJ cord-293714-s6ezxi5r 94 8 trigger trigger NN cord-293714-s6ezxi5r 94 9 of of IN cord-293714-s6ezxi5r 94 10 KS KS NNP cord-293714-s6ezxi5r 94 11 may may MD cord-293714-s6ezxi5r 94 12 be be VB cord-293714-s6ezxi5r 94 13 wind wind NN cord-293714-s6ezxi5r 94 14 - - HYPH cord-293714-s6ezxi5r 94 15 borne bear VBN cord-293714-s6ezxi5r 94 16 , , , cord-293714-s6ezxi5r 94 17 and and CC cord-293714-s6ezxi5r 94 18 this this DT cord-293714-s6ezxi5r 94 19 has have VBZ cord-293714-s6ezxi5r 94 20 led lead VBN cord-293714-s6ezxi5r 94 21 some some DT cord-293714-s6ezxi5r 94 22 experts expert NNS cord-293714-s6ezxi5r 94 23 to to TO cord-293714-s6ezxi5r 94 24 suggest suggest VB cord-293714-s6ezxi5r 94 25 that that IN cord-293714-s6ezxi5r 94 26 efforts effort NNS cord-293714-s6ezxi5r 94 27 to to TO cord-293714-s6ezxi5r 94 28 isolate isolate VB cord-293714-s6ezxi5r 94 29 the the DT cord-293714-s6ezxi5r 94 30 causative causative JJ cord-293714-s6ezxi5r 94 31 agent agent NN cord-293714-s6ezxi5r 94 32 should should MD cord-293714-s6ezxi5r 94 33 concentrate concentrate VB cord-293714-s6ezxi5r 94 34 on on IN cord-293714-s6ezxi5r 94 35 the the DT cord-293714-s6ezxi5r 94 36 microbiology microbiology NN cord-293714-s6ezxi5r 94 37 of of IN cord-293714-s6ezxi5r 94 38 aerosols aerosol NNS cord-293714-s6ezxi5r 94 39 . . . cord-293714-s6ezxi5r 95 1 43 43 CD cord-293714-s6ezxi5r 95 2 Finally finally RB cord-293714-s6ezxi5r 95 3 , , , cord-293714-s6ezxi5r 95 4 children child NNS cord-293714-s6ezxi5r 95 5 in in IN cord-293714-s6ezxi5r 95 6 the the DT cord-293714-s6ezxi5r 95 7 first first JJ cord-293714-s6ezxi5r 95 8 months month NNS cord-293714-s6ezxi5r 95 9 of of IN cord-293714-s6ezxi5r 95 10 life life NN cord-293714-s6ezxi5r 95 11 only only RB cord-293714-s6ezxi5r 95 12 exceptionally exceptionally RB cord-293714-s6ezxi5r 95 13 develop develop VBP cord-293714-s6ezxi5r 95 14 KS KS NNP cord-293714-s6ezxi5r 95 15 , , , cord-293714-s6ezxi5r 95 16 which which WDT cord-293714-s6ezxi5r 95 17 supports support VBZ cord-293714-s6ezxi5r 95 18 the the DT cord-293714-s6ezxi5r 95 19 hypothesis hypothesis NN cord-293714-s6ezxi5r 95 20 that that IN cord-293714-s6ezxi5r 95 21 most most JJS cord-293714-s6ezxi5r 95 22 infants infant NNS cord-293714-s6ezxi5r 95 23 are be VBP cord-293714-s6ezxi5r 95 24 protected protect VBN cord-293714-s6ezxi5r 95 25 by by IN cord-293714-s6ezxi5r 95 26 passively passively RB cord-293714-s6ezxi5r 95 27 acquired acquire VBN cord-293714-s6ezxi5r 95 28 specific specific JJ cord-293714-s6ezxi5r 95 29 maternal maternal JJ cord-293714-s6ezxi5r 95 30 antibodies antibody NNS cord-293714-s6ezxi5r 95 31 against against IN cord-293714-s6ezxi5r 95 32 the the DT cord-293714-s6ezxi5r 95 33 possible possible JJ cord-293714-s6ezxi5r 95 34 causative causative JJ cord-293714-s6ezxi5r 95 35 agent(s agent(s NNP cord-293714-s6ezxi5r 95 36 ) ) -RRB- cord-293714-s6ezxi5r 95 37 . . . cord-293714-s6ezxi5r 96 1 On on IN cord-293714-s6ezxi5r 96 2 the the DT cord-293714-s6ezxi5r 96 3 other other JJ cord-293714-s6ezxi5r 96 4 hand hand NN cord-293714-s6ezxi5r 96 5 , , , cord-293714-s6ezxi5r 96 6 the the DT cord-293714-s6ezxi5r 96 7 very very RB cord-293714-s6ezxi5r 96 8 low low JJ cord-293714-s6ezxi5r 96 9 incidence incidence NN cord-293714-s6ezxi5r 96 10 of of IN cord-293714-s6ezxi5r 96 11 KS KS NNP cord-293714-s6ezxi5r 96 12 beyond beyond IN cord-293714-s6ezxi5r 96 13 the the DT cord-293714-s6ezxi5r 96 14 fifth fifth JJ cord-293714-s6ezxi5r 96 15 year year NN cord-293714-s6ezxi5r 96 16 suggests suggest VBZ cord-293714-s6ezxi5r 96 17 that that IN cord-293714-s6ezxi5r 96 18 most most JJS cord-293714-s6ezxi5r 96 19 children child NNS cord-293714-s6ezxi5r 96 20 are be VBP cord-293714-s6ezxi5r 96 21 infected infect VBN cord-293714-s6ezxi5r 96 22 uneventfully uneventfully RB cord-293714-s6ezxi5r 96 23 by by IN cord-293714-s6ezxi5r 96 24 one one CD cord-293714-s6ezxi5r 96 25 or or CC cord-293714-s6ezxi5r 96 26 more more JJR cord-293714-s6ezxi5r 96 27 of of IN cord-293714-s6ezxi5r 96 28 the the DT cord-293714-s6ezxi5r 96 29 infectious infectious JJ cord-293714-s6ezxi5r 96 30 agents agent NNS cord-293714-s6ezxi5r 96 31 associated associate VBN cord-293714-s6ezxi5r 96 32 with with IN cord-293714-s6ezxi5r 96 33 KS KS NNP cord-293714-s6ezxi5r 96 34 in in IN cord-293714-s6ezxi5r 96 35 early early JJ cord-293714-s6ezxi5r 96 36 life life NN cord-293714-s6ezxi5r 96 37 and and CC cord-293714-s6ezxi5r 96 38 can can MD cord-293714-s6ezxi5r 96 39 then then RB cord-293714-s6ezxi5r 96 40 mount mount VB cord-293714-s6ezxi5r 96 41 a a DT cord-293714-s6ezxi5r 96 42 long long RB cord-293714-s6ezxi5r 96 43 - - HYPH cord-293714-s6ezxi5r 96 44 lasting last VBG cord-293714-s6ezxi5r 96 45 , , , cord-293714-s6ezxi5r 96 46 strong strong JJ cord-293714-s6ezxi5r 96 47 and and CC cord-293714-s6ezxi5r 96 48 protective protective JJ cord-293714-s6ezxi5r 96 49 immune immune JJ cord-293714-s6ezxi5r 96 50 response response NN cord-293714-s6ezxi5r 96 51 . . . cord-293714-s6ezxi5r 97 1 Recurrences recurrence NNS cord-293714-s6ezxi5r 97 2 of of IN cord-293714-s6ezxi5r 97 3 KS KS NNP cord-293714-s6ezxi5r 97 4 have have VBP cord-293714-s6ezxi5r 97 5 been be VBN cord-293714-s6ezxi5r 97 6 reported report VBN cord-293714-s6ezxi5r 97 7 in in IN cord-293714-s6ezxi5r 97 8 only only RB cord-293714-s6ezxi5r 97 9 1e3 1e3 CD cord-293714-s6ezxi5r 97 10 % % NN cord-293714-s6ezxi5r 97 11 of of IN cord-293714-s6ezxi5r 97 12 children child NNS cord-293714-s6ezxi5r 97 13 , , , cord-293714-s6ezxi5r 97 14 and and CC cord-293714-s6ezxi5r 97 15 are be VBP cord-293714-s6ezxi5r 97 16 best well RBS cord-293714-s6ezxi5r 97 17 documented document VBN cord-293714-s6ezxi5r 97 18 in in IN cord-293714-s6ezxi5r 97 19 Japan Japan NNP cord-293714-s6ezxi5r 97 20 . . . cord-293714-s6ezxi5r 98 1 44 44 CD cord-293714-s6ezxi5r 98 2 _SP cord-293714-s6ezxi5r 99 1 The the DT cord-293714-s6ezxi5r 99 2 clinical clinical JJ cord-293714-s6ezxi5r 99 3 findings finding NNS cord-293714-s6ezxi5r 99 4 of of IN cord-293714-s6ezxi5r 99 5 fever fever NN cord-293714-s6ezxi5r 99 6 , , , cord-293714-s6ezxi5r 99 7 an an DT cord-293714-s6ezxi5r 99 8 erythematous erythematous JJ cord-293714-s6ezxi5r 99 9 pharynx pharynx NN cord-293714-s6ezxi5r 99 10 , , , cord-293714-s6ezxi5r 99 11 conjunctival conjunctival NN cord-293714-s6ezxi5r 99 12 injection injection NN cord-293714-s6ezxi5r 99 13 , , , cord-293714-s6ezxi5r 99 14 rash rash JJ cord-293714-s6ezxi5r 99 15 , , , cord-293714-s6ezxi5r 99 16 oedema oedema NN cord-293714-s6ezxi5r 99 17 of of IN cord-293714-s6ezxi5r 99 18 the the DT cord-293714-s6ezxi5r 99 19 extremities extremity NNS cord-293714-s6ezxi5r 99 20 and and CC cord-293714-s6ezxi5r 99 21 cervical cervical JJ cord-293714-s6ezxi5r 99 22 adenitis adenitis NN cord-293714-s6ezxi5r 99 23 in in IN cord-293714-s6ezxi5r 99 24 patients patient NNS cord-293714-s6ezxi5r 99 25 with with IN cord-293714-s6ezxi5r 99 26 KS KS NNP cord-293714-s6ezxi5r 99 27 , , , cord-293714-s6ezxi5r 99 28 and and CC cord-293714-s6ezxi5r 99 29 the the DT cord-293714-s6ezxi5r 99 30 clear clear JJ cord-293714-s6ezxi5r 99 31 tendency tendency NN cord-293714-s6ezxi5r 99 32 of of IN cord-293714-s6ezxi5r 99 33 these these DT cord-293714-s6ezxi5r 99 34 signs sign NNS cord-293714-s6ezxi5r 99 35 to to TO cord-293714-s6ezxi5r 99 36 resolve resolve VB cord-293714-s6ezxi5r 99 37 spontaneously spontaneously RB cord-293714-s6ezxi5r 99 38 even even RB cord-293714-s6ezxi5r 99 39 without without IN cord-293714-s6ezxi5r 99 40 treatment treatment NN cord-293714-s6ezxi5r 99 41 also also RB cord-293714-s6ezxi5r 99 42 support support VBP cord-293714-s6ezxi5r 99 43 an an DT cord-293714-s6ezxi5r 99 44 infectious infectious JJ cord-293714-s6ezxi5r 99 45 aetiology aetiology NN cord-293714-s6ezxi5r 99 46 . . . cord-293714-s6ezxi5r 100 1 A a DT cord-293714-s6ezxi5r 100 2 number number NN cord-293714-s6ezxi5r 100 3 of of IN cord-293714-s6ezxi5r 100 4 viral viral JJ cord-293714-s6ezxi5r 100 5 diseases disease NNS cord-293714-s6ezxi5r 100 6 have have VBP cord-293714-s6ezxi5r 100 7 a a DT cord-293714-s6ezxi5r 100 8 similar similar JJ cord-293714-s6ezxi5r 100 9 clinical clinical JJ cord-293714-s6ezxi5r 100 10 picture picture NN cord-293714-s6ezxi5r 100 11 . . . cord-293714-s6ezxi5r 101 1 Moreover moreover RB cord-293714-s6ezxi5r 101 2 , , , cord-293714-s6ezxi5r 101 3 some some DT cord-293714-s6ezxi5r 101 4 of of IN cord-293714-s6ezxi5r 101 5 the the DT cord-293714-s6ezxi5r 101 6 clinical clinical JJ cord-293714-s6ezxi5r 101 7 features feature NNS cord-293714-s6ezxi5r 101 8 of of IN cord-293714-s6ezxi5r 101 9 KS KS NNP cord-293714-s6ezxi5r 101 10 , , , cord-293714-s6ezxi5r 101 11 such such JJ cord-293714-s6ezxi5r 101 12 as as IN cord-293714-s6ezxi5r 101 13 mucous mucous JJ cord-293714-s6ezxi5r 101 14 membrane membrane NN cord-293714-s6ezxi5r 101 15 erythema erythema NN cord-293714-s6ezxi5r 101 16 and and CC cord-293714-s6ezxi5r 101 17 desquamation desquamation NN cord-293714-s6ezxi5r 101 18 of of IN cord-293714-s6ezxi5r 101 19 the the DT cord-293714-s6ezxi5r 101 20 fingers finger NNS cord-293714-s6ezxi5r 101 21 and and CC cord-293714-s6ezxi5r 101 22 toes toe NNS cord-293714-s6ezxi5r 101 23 ( ( -LRB- cord-293714-s6ezxi5r 101 24 usually usually RB cord-293714-s6ezxi5r 101 25 beginning begin VBG cord-293714-s6ezxi5r 101 26 within within IN cord-293714-s6ezxi5r 101 27 2e3 2e3 CD cord-293714-s6ezxi5r 101 28 weeks week NNS cord-293714-s6ezxi5r 101 29 of of IN cord-293714-s6ezxi5r 101 30 the the DT cord-293714-s6ezxi5r 101 31 onset onset NN cord-293714-s6ezxi5r 101 32 of of IN cord-293714-s6ezxi5r 101 33 fever fever NN cord-293714-s6ezxi5r 101 34 ) ) -RRB- cord-293714-s6ezxi5r 101 35 , , , cord-293714-s6ezxi5r 101 36 overlap overlap VBP cord-293714-s6ezxi5r 101 37 those those DT cord-293714-s6ezxi5r 101 38 associated associate VBN cord-293714-s6ezxi5r 101 39 with with IN cord-293714-s6ezxi5r 101 40 some some DT cord-293714-s6ezxi5r 101 41 bacterial bacterial JJ cord-293714-s6ezxi5r 101 42 diseases disease NNS cord-293714-s6ezxi5r 101 43 that that WDT cord-293714-s6ezxi5r 101 44 are be VBP cord-293714-s6ezxi5r 101 45 considered consider VBN cord-293714-s6ezxi5r 101 46 to to TO cord-293714-s6ezxi5r 101 47 be be VB cord-293714-s6ezxi5r 101 48 a a DT cord-293714-s6ezxi5r 101 49 consequence consequence NN cord-293714-s6ezxi5r 101 50 of of IN cord-293714-s6ezxi5r 101 51 the the DT cord-293714-s6ezxi5r 101 52 superantigen superantigen NN cord-293714-s6ezxi5r 101 53 ( ( -LRB- cord-293714-s6ezxi5r 101 54 SA)-mediated sa)-mediated CD cord-293714-s6ezxi5r 101 55 activation activation NN cord-293714-s6ezxi5r 101 56 of of IN cord-293714-s6ezxi5r 101 57 T T NNP cord-293714-s6ezxi5r 101 58 cells cell NNS cord-293714-s6ezxi5r 101 59 leading lead VBG cord-293714-s6ezxi5r 101 60 to to IN cord-293714-s6ezxi5r 101 61 the the DT cord-293714-s6ezxi5r 101 62 overproduction overproduction NN cord-293714-s6ezxi5r 101 63 of of IN cord-293714-s6ezxi5r 101 64 cytokines cytokine NNS cord-293714-s6ezxi5r 101 65 , , , cord-293714-s6ezxi5r 101 66 systemic systemic JJ cord-293714-s6ezxi5r 101 67 inflammation inflammation NN cord-293714-s6ezxi5r 101 68 and and CC cord-293714-s6ezxi5r 101 69 shock shock NN cord-293714-s6ezxi5r 101 70 . . . cord-293714-s6ezxi5r 102 1 45e47 45e47 CD cord-293714-s6ezxi5r 103 1 The the DT cord-293714-s6ezxi5r 103 2 best good JJS cord-293714-s6ezxi5r 103 3 examples example NNS cord-293714-s6ezxi5r 103 4 in in IN cord-293714-s6ezxi5r 103 5 this this DT cord-293714-s6ezxi5r 103 6 regard regard NN cord-293714-s6ezxi5r 103 7 are be VBP cord-293714-s6ezxi5r 103 8 toxic toxic JJ cord-293714-s6ezxi5r 103 9 shock shock NN cord-293714-s6ezxi5r 103 10 syndrome syndrome NN cord-293714-s6ezxi5r 103 11 ( ( -LRB- cord-293714-s6ezxi5r 103 12 TSS TSS NNP cord-293714-s6ezxi5r 103 13 ) ) -RRB- cord-293714-s6ezxi5r 103 14 and and CC cord-293714-s6ezxi5r 103 15 scarlet scarlet JJ cord-293714-s6ezxi5r 103 16 fever fever NN cord-293714-s6ezxi5r 103 17 due due IN cord-293714-s6ezxi5r 103 18 to to IN cord-293714-s6ezxi5r 103 19 S. S. NNP cord-293714-s6ezxi5r 103 20 aureus aureus NN cord-293714-s6ezxi5r 103 21 , , , cord-293714-s6ezxi5r 103 22 and and CC cord-293714-s6ezxi5r 103 23 streptococcal streptococcal JJ cord-293714-s6ezxi5r 103 24 toxic toxic JJ cord-293714-s6ezxi5r 103 25 shock shock NN cord-293714-s6ezxi5r 103 26 syndrome syndrome NN cord-293714-s6ezxi5r 103 27 ( ( -LRB- cord-293714-s6ezxi5r 103 28 STSS STSS NNP cord-293714-s6ezxi5r 103 29 ) ) -RRB- cord-293714-s6ezxi5r 103 30 due due IN cord-293714-s6ezxi5r 103 31 to to IN cord-293714-s6ezxi5r 103 32 Streptococcus streptococcus NN cord-293714-s6ezxi5r 103 33 pneumoniae pneumoniae NN cord-293714-s6ezxi5r 103 34 . . . cord-293714-s6ezxi5r 104 1 The the DT cord-293714-s6ezxi5r 104 2 similarity similarity NN cord-293714-s6ezxi5r 104 3 between between IN cord-293714-s6ezxi5r 104 4 these these DT cord-293714-s6ezxi5r 104 5 conditions condition NNS cord-293714-s6ezxi5r 104 6 and and CC cord-293714-s6ezxi5r 104 7 KS KS NNP cord-293714-s6ezxi5r 104 8 has have VBZ cord-293714-s6ezxi5r 104 9 led lead VBN cord-293714-s6ezxi5r 104 10 to to IN cord-293714-s6ezxi5r 104 11 the the DT cord-293714-s6ezxi5r 104 12 conclusion conclusion NN cord-293714-s6ezxi5r 104 13 that that IN cord-293714-s6ezxi5r 104 14 , , , cord-293714-s6ezxi5r 104 15 at at IN cord-293714-s6ezxi5r 104 16 least least JJS cord-293714-s6ezxi5r 104 17 in in IN cord-293714-s6ezxi5r 104 18 some some DT cord-293714-s6ezxi5r 104 19 cases case NNS cord-293714-s6ezxi5r 104 20 , , , cord-293714-s6ezxi5r 104 21 KS KS NNP cord-293714-s6ezxi5r 104 22 may may MD cord-293714-s6ezxi5r 104 23 follow follow VB cord-293714-s6ezxi5r 104 24 an an DT cord-293714-s6ezxi5r 104 25 infection infection NN cord-293714-s6ezxi5r 104 26 due due IN cord-293714-s6ezxi5r 104 27 to to IN cord-293714-s6ezxi5r 104 28 an an DT cord-293714-s6ezxi5r 104 29 SAproducing saproduce VBG cord-293714-s6ezxi5r 104 30 pathogen pathogen NN cord-293714-s6ezxi5r 104 31 . . . cord-293714-s6ezxi5r 105 1 A a DT cord-293714-s6ezxi5r 105 2 number number NN cord-293714-s6ezxi5r 105 3 of of IN cord-293714-s6ezxi5r 105 4 SAs SAs NNP cord-293714-s6ezxi5r 105 5 have have VBP cord-293714-s6ezxi5r 105 6 been be VBN cord-293714-s6ezxi5r 105 7 identified identify VBN cord-293714-s6ezxi5r 105 8 : : : cord-293714-s6ezxi5r 105 9 the the DT cord-293714-s6ezxi5r 105 10 most most RBS cord-293714-s6ezxi5r 105 11 widespread widespread JJ cord-293714-s6ezxi5r 105 12 bacterial bacterial JJ cord-293714-s6ezxi5r 105 13 pathogens pathogen NNS cord-293714-s6ezxi5r 105 14 are be VBP cord-293714-s6ezxi5r 105 15 S. S. NNP cord-293714-s6ezxi5r 105 16 aureus aureus NN cord-293714-s6ezxi5r 105 17 and and CC cord-293714-s6ezxi5r 105 18 S. S. NNP cord-293714-s6ezxi5r 105 19 pneumoniae pneumoniae NN cord-293714-s6ezxi5r 105 20 , , , cord-293714-s6ezxi5r 105 21 but but CC cord-293714-s6ezxi5r 105 22 Yersinia Yersinia NNP cord-293714-s6ezxi5r 105 23 pseudotuberculosis pseudotuberculosis NN cord-293714-s6ezxi5r 105 24 , , , cord-293714-s6ezxi5r 105 25 Mycoplasma Mycoplasma NNP cord-293714-s6ezxi5r 105 26 pneumoniae pneumoniae NNS cord-293714-s6ezxi5r 105 27 and and CC cord-293714-s6ezxi5r 105 28 Mycobacterium Mycobacterium NNP cord-293714-s6ezxi5r 105 29 tuberculosis tuberculosis NN cord-293714-s6ezxi5r 105 30 have have VBP cord-293714-s6ezxi5r 105 31 also also RB cord-293714-s6ezxi5r 105 32 been be VBN cord-293714-s6ezxi5r 105 33 associated associate VBN cord-293714-s6ezxi5r 105 34 with with IN cord-293714-s6ezxi5r 105 35 SA SA NNP cord-293714-s6ezxi5r 105 36 formation formation NN cord-293714-s6ezxi5r 105 37 45 45 CD cord-293714-s6ezxi5r 105 38 ; ; : cord-293714-s6ezxi5r 105 39 among among IN cord-293714-s6ezxi5r 105 40 viruses virus NNS cord-293714-s6ezxi5r 105 41 , , , cord-293714-s6ezxi5r 105 42 SAs sa NNS cord-293714-s6ezxi5r 105 43 have have VBP cord-293714-s6ezxi5r 105 44 been be VBN cord-293714-s6ezxi5r 105 45 found find VBN cord-293714-s6ezxi5r 105 46 in in IN cord-293714-s6ezxi5r 105 47 Epstein Epstein NNP cord-293714-s6ezxi5r 105 48 Barr Barr NNP cord-293714-s6ezxi5r 105 49 virus virus NN cord-293714-s6ezxi5r 105 50 , , , cord-293714-s6ezxi5r 105 51 rabies rabies NN cord-293714-s6ezxi5r 105 52 virus virus NN cord-293714-s6ezxi5r 105 53 and and CC cord-293714-s6ezxi5r 105 54 mouse mouse NN cord-293714-s6ezxi5r 105 55 leukaemia leukaemia NN cord-293714-s6ezxi5r 105 56 virus virus NN cord-293714-s6ezxi5r 105 57 . . . cord-293714-s6ezxi5r 106 1 46 46 CD cord-293714-s6ezxi5r 106 2 SAs sa NNS cord-293714-s6ezxi5r 106 3 are be VBP cord-293714-s6ezxi5r 106 4 a a DT cord-293714-s6ezxi5r 106 5 family family NN cord-293714-s6ezxi5r 106 6 of of IN cord-293714-s6ezxi5r 106 7 potent potent JJ cord-293714-s6ezxi5r 106 8 immunostimulatory immunostimulatory NNP cord-293714-s6ezxi5r 106 9 proteins protein NNS cord-293714-s6ezxi5r 106 10 whose whose WP$ cord-293714-s6ezxi5r 106 11 particular particular JJ cord-293714-s6ezxi5r 106 12 structures structure NNS cord-293714-s6ezxi5r 106 13 and and CC cord-293714-s6ezxi5r 106 14 sequences sequence NNS cord-293714-s6ezxi5r 106 15 lead lead VBP cord-293714-s6ezxi5r 106 16 to to IN cord-293714-s6ezxi5r 106 17 a a DT cord-293714-s6ezxi5r 106 18 shared share VBN cord-293714-s6ezxi5r 106 19 ability ability NN cord-293714-s6ezxi5r 106 20 to to IN cord-293714-s6ezxi5r 106 21 by by IN cord-293714-s6ezxi5r 106 22 - - HYPH cord-293714-s6ezxi5r 106 23 pass pass VB cord-293714-s6ezxi5r 106 24 the the DT cord-293714-s6ezxi5r 106 25 mechanism mechanism NN cord-293714-s6ezxi5r 106 26 of of IN cord-293714-s6ezxi5r 106 27 conventional conventional JJ cord-293714-s6ezxi5r 106 28 major major JJ cord-293714-s6ezxi5r 106 29 histocompatibility histocompatibility NN cord-293714-s6ezxi5r 106 30 complex complex NN cord-293714-s6ezxi5r 106 31 ( ( -LRB- cord-293714-s6ezxi5r 106 32 MHC)-restricted mhc)-restricted JJ cord-293714-s6ezxi5r 106 33 antigen antigen NN cord-293714-s6ezxi5r 106 34 processing processing NN cord-293714-s6ezxi5r 106 35 . . . cord-293714-s6ezxi5r 107 1 When when WRB cord-293714-s6ezxi5r 107 2 an an DT cord-293714-s6ezxi5r 107 3 SA SA NNP cord-293714-s6ezxi5r 107 4 is be VBZ cord-293714-s6ezxi5r 107 5 involved involve VBN cord-293714-s6ezxi5r 107 6 , , , cord-293714-s6ezxi5r 107 7 T t NN cord-293714-s6ezxi5r 107 8 cell cell NN cord-293714-s6ezxi5r 107 9 responses response NNS cord-293714-s6ezxi5r 107 10 are be VBP cord-293714-s6ezxi5r 107 11 quantitatively quantitatively RB cord-293714-s6ezxi5r 107 12 and and CC cord-293714-s6ezxi5r 107 13 qualitatively qualitatively RB cord-293714-s6ezxi5r 107 14 different different JJ cord-293714-s6ezxi5r 107 15 from from IN cord-293714-s6ezxi5r 107 16 conventional conventional JJ cord-293714-s6ezxi5r 107 17 T T NNP cord-293714-s6ezxi5r 107 18 cell cell NN cord-293714-s6ezxi5r 107 19 activation activation NN cord-293714-s6ezxi5r 107 20 by by IN cord-293714-s6ezxi5r 107 21 normal normal JJ cord-293714-s6ezxi5r 107 22 antigens antigen NNS cord-293714-s6ezxi5r 107 23 . . . cord-293714-s6ezxi5r 108 1 In in IN cord-293714-s6ezxi5r 108 2 particular particular JJ cord-293714-s6ezxi5r 108 3 , , , cord-293714-s6ezxi5r 108 4 SAs sa NNS cord-293714-s6ezxi5r 108 5 activate activate VBP cord-293714-s6ezxi5r 108 6 T T NNP cord-293714-s6ezxi5r 108 7 cells cell NNS cord-293714-s6ezxi5r 108 8 in in IN cord-293714-s6ezxi5r 108 9 a a DT cord-293714-s6ezxi5r 108 10 manner manner NN cord-293714-s6ezxi5r 108 11 that that WDT cord-293714-s6ezxi5r 108 12 depends depend VBZ cord-293714-s6ezxi5r 108 13 on on IN cord-293714-s6ezxi5r 108 14 the the DT cord-293714-s6ezxi5r 108 15 T T NNP cord-293714-s6ezxi5r 108 16 cell cell NN cord-293714-s6ezxi5r 108 17 receptor receptor NN cord-293714-s6ezxi5r 108 18 variable variable NN cord-293714-s6ezxi5r 108 19 domain domain NN cord-293714-s6ezxi5r 108 20 ( ( -LRB- cord-293714-s6ezxi5r 108 21 Vb Vb NNP cord-293714-s6ezxi5r 108 22 ) ) -RRB- cord-293714-s6ezxi5r 108 23 , , , cord-293714-s6ezxi5r 108 24 and and CC cord-293714-s6ezxi5r 108 25 so so RB cord-293714-s6ezxi5r 108 26 a a DT cord-293714-s6ezxi5r 108 27 large large JJ cord-293714-s6ezxi5r 108 28 number number NN cord-293714-s6ezxi5r 108 29 of of IN cord-293714-s6ezxi5r 108 30 T t NN cord-293714-s6ezxi5r 108 31 cells cell NNS cord-293714-s6ezxi5r 108 32 can can MD cord-293714-s6ezxi5r 108 33 be be VB cord-293714-s6ezxi5r 108 34 simultaneously simultaneously RB cord-293714-s6ezxi5r 108 35 activated activate VBN cord-293714-s6ezxi5r 108 36 . . . cord-293714-s6ezxi5r 109 1 85 85 CD cord-293714-s6ezxi5r 110 1 The the DT cord-293714-s6ezxi5r 110 2 activation activation NN cord-293714-s6ezxi5r 110 3 is be VBZ cord-293714-s6ezxi5r 110 4 extremely extremely RB cord-293714-s6ezxi5r 110 5 potent potent JJ cord-293714-s6ezxi5r 110 6 and and CC cord-293714-s6ezxi5r 110 7 a a DT cord-293714-s6ezxi5r 110 8 number number NN cord-293714-s6ezxi5r 110 9 of of IN cord-293714-s6ezxi5r 110 10 studies study NNS cord-293714-s6ezxi5r 110 11 have have VBP cord-293714-s6ezxi5r 110 12 found find VBN cord-293714-s6ezxi5r 110 13 that that IN cord-293714-s6ezxi5r 110 14 KS KS NNP cord-293714-s6ezxi5r 110 15 is be VBZ cord-293714-s6ezxi5r 110 16 characterised characterise VBN cord-293714-s6ezxi5r 110 17 by by IN cord-293714-s6ezxi5r 110 18 the the DT cord-293714-s6ezxi5r 110 19 marked marked JJ cord-293714-s6ezxi5r 110 20 activation activation NN cord-293714-s6ezxi5r 110 21 of of IN cord-293714-s6ezxi5r 110 22 T T NNP cord-293714-s6ezxi5r 110 23 cells cell NNS cord-293714-s6ezxi5r 110 24 and and CC cord-293714-s6ezxi5r 110 25 monocytes monocyte NNS cord-293714-s6ezxi5r 110 26 / / SYM cord-293714-s6ezxi5r 110 27 macrophages macrophage NNS cord-293714-s6ezxi5r 110 28 , , , cord-293714-s6ezxi5r 110 29 and and CC cord-293714-s6ezxi5r 110 30 increased increase VBN cord-293714-s6ezxi5r 110 31 production production NN cord-293714-s6ezxi5r 110 32 of of IN cord-293714-s6ezxi5r 110 33 IL-1b IL-1b NNP cord-293714-s6ezxi5r 110 34 , , , cord-293714-s6ezxi5r 110 35 TNF TNF NNP cord-293714-s6ezxi5r 110 36 - - : cord-293714-s6ezxi5r 110 37 a a NNP cord-293714-s6ezxi5r 110 38 and and CC cord-293714-s6ezxi5r 110 39 IL-6 IL-6 NNP cord-293714-s6ezxi5r 110 40 , , , cord-293714-s6ezxi5r 110 41 which which WDT cord-293714-s6ezxi5r 110 42 are be VBP cord-293714-s6ezxi5r 110 43 the the DT cord-293714-s6ezxi5r 110 44 same same JJ cord-293714-s6ezxi5r 110 45 immunological immunological JJ cord-293714-s6ezxi5r 110 46 findings finding NNS cord-293714-s6ezxi5r 110 47 as as IN cord-293714-s6ezxi5r 110 48 those those DT cord-293714-s6ezxi5r 110 49 of of IN cord-293714-s6ezxi5r 110 50 TSS TSS NNP cord-293714-s6ezxi5r 110 51 . . . cord-293714-s6ezxi5r 111 1 47 47 CD cord-293714-s6ezxi5r 112 1 Although although IN cord-293714-s6ezxi5r 112 2 some some DT cord-293714-s6ezxi5r 112 3 attempts attempt NNS cord-293714-s6ezxi5r 112 4 to to TO cord-293714-s6ezxi5r 112 5 demonstrate demonstrate VB cord-293714-s6ezxi5r 112 6 the the DT cord-293714-s6ezxi5r 112 7 presence presence NN cord-293714-s6ezxi5r 112 8 of of IN cord-293714-s6ezxi5r 112 9 SA sa NN cord-293714-s6ezxi5r 112 10 - - HYPH cord-293714-s6ezxi5r 112 11 producing produce VBG cord-293714-s6ezxi5r 112 12 pathogens pathogen NNS cord-293714-s6ezxi5r 112 13 in in IN cord-293714-s6ezxi5r 112 14 children child NNS cord-293714-s6ezxi5r 112 15 with with IN cord-293714-s6ezxi5r 112 16 KS KS NNP cord-293714-s6ezxi5r 112 17 have have VBP cord-293714-s6ezxi5r 112 18 led lead VBN cord-293714-s6ezxi5r 112 19 to to IN cord-293714-s6ezxi5r 112 20 negative negative JJ cord-293714-s6ezxi5r 112 21 results result NNS cord-293714-s6ezxi5r 112 22 , , , cord-293714-s6ezxi5r 112 23 48e51 48e51 CD cord-293714-s6ezxi5r 112 24 others other NNS cord-293714-s6ezxi5r 112 25 have have VBP cord-293714-s6ezxi5r 112 26 provided provide VBN cord-293714-s6ezxi5r 112 27 data datum NNS cord-293714-s6ezxi5r 112 28 suggesting suggest VBG cord-293714-s6ezxi5r 112 29 the the DT cord-293714-s6ezxi5r 112 30 direct direct JJ cord-293714-s6ezxi5r 112 31 involvement involvement NN cord-293714-s6ezxi5r 112 32 of of IN cord-293714-s6ezxi5r 112 33 SAs SAs NNP cord-293714-s6ezxi5r 112 34 . . . cord-293714-s6ezxi5r 113 1 Leung Leung NNP cord-293714-s6ezxi5r 113 2 et et NNP cord-293714-s6ezxi5r 113 3 al al NNP cord-293714-s6ezxi5r 113 4 . . . cord-293714-s6ezxi5r 114 1 blindly blindly RB cord-293714-s6ezxi5r 114 2 studied study VBD cord-293714-s6ezxi5r 114 3 bacterial bacterial JJ cord-293714-s6ezxi5r 114 4 SAs sa NNS cord-293714-s6ezxi5r 114 5 potentially potentially RB cord-293714-s6ezxi5r 114 6 involved involve VBN cord-293714-s6ezxi5r 114 7 in in IN cord-293714-s6ezxi5r 114 8 the the DT cord-293714-s6ezxi5r 114 9 pathogenesis pathogenesis NN cord-293714-s6ezxi5r 114 10 of of IN cord-293714-s6ezxi5r 114 11 KS KS NNP cord-293714-s6ezxi5r 114 12 in in IN cord-293714-s6ezxi5r 114 13 cultures culture NNS cord-293714-s6ezxi5r 114 14 of of IN cord-293714-s6ezxi5r 114 15 patients patient NNS cord-293714-s6ezxi5r 114 16 in in IN cord-293714-s6ezxi5r 114 17 the the DT cord-293714-s6ezxi5r 114 18 acute acute JJ cord-293714-s6ezxi5r 114 19 phase phase NN cord-293714-s6ezxi5r 114 20 and and CC cord-293714-s6ezxi5r 114 21 controls control NNS cord-293714-s6ezxi5r 114 22 , , , cord-293714-s6ezxi5r 114 23 52 52 CD cord-293714-s6ezxi5r 114 24 and and CC cord-293714-s6ezxi5r 114 25 found find VBD cord-293714-s6ezxi5r 114 26 SA sa NN cord-293714-s6ezxi5r 114 27 - - HYPH cord-293714-s6ezxi5r 114 28 producing produce VBG cord-293714-s6ezxi5r 114 29 bacteria bacteria NNS cord-293714-s6ezxi5r 114 30 in in IN cord-293714-s6ezxi5r 114 31 13 13 CD cord-293714-s6ezxi5r 114 32 of of IN cord-293714-s6ezxi5r 114 33 the the DT cord-293714-s6ezxi5r 114 34 16 16 CD cord-293714-s6ezxi5r 114 35 patients patient NNS cord-293714-s6ezxi5r 114 36 but but CC cord-293714-s6ezxi5r 114 37 in in IN cord-293714-s6ezxi5r 114 38 only only RB cord-293714-s6ezxi5r 114 39 one one CD cord-293714-s6ezxi5r 114 40 of of IN cord-293714-s6ezxi5r 114 41 the the DT cord-293714-s6ezxi5r 114 42 15 15 CD cord-293714-s6ezxi5r 114 43 controls control NNS cord-293714-s6ezxi5r 114 44 ( ( -LRB- cord-293714-s6ezxi5r 114 45 p p NN cord-293714-s6ezxi5r 114 46 < < XX cord-293714-s6ezxi5r 114 47 0.0001 0.0001 CD cord-293714-s6ezxi5r 114 48 ) ) -RRB- cord-293714-s6ezxi5r 114 49 . . . cord-293714-s6ezxi5r 115 1 Eleven eleven CD cord-293714-s6ezxi5r 115 2 of of IN cord-293714-s6ezxi5r 115 3 the the DT cord-293714-s6ezxi5r 115 4 13 13 CD cord-293714-s6ezxi5r 115 5 toxin toxin NN cord-293714-s6ezxi5r 115 6 - - HYPH cord-293714-s6ezxi5r 115 7 positive positive JJ cord-293714-s6ezxi5r 115 8 cultures culture NNS cord-293714-s6ezxi5r 115 9 from from IN cord-293714-s6ezxi5r 115 10 the the DT cord-293714-s6ezxi5r 115 11 patients patient NNS cord-293714-s6ezxi5r 115 12 with with IN cord-293714-s6ezxi5r 115 13 KS KS NNP cord-293714-s6ezxi5r 115 14 contained contain VBD cord-293714-s6ezxi5r 115 15 toxic toxic JJ cord-293714-s6ezxi5r 115 16 shock shock NN cord-293714-s6ezxi5r 115 17 syndrome syndrome NN cord-293714-s6ezxi5r 115 18 toxin toxin NN cord-293714-s6ezxi5r 115 19 ( ( -LRB- cord-293714-s6ezxi5r 115 20 TSST)-1 tsst)-1 DT cord-293714-s6ezxi5r 115 21 secreting secrete VBG cord-293714-s6ezxi5r 115 22 S. S. NNP cord-293714-s6ezxi5r 115 23 aureus aureus NN cord-293714-s6ezxi5r 115 24 , , , cord-293714-s6ezxi5r 115 25 and and CC cord-293714-s6ezxi5r 115 26 the the DT cord-293714-s6ezxi5r 115 27 remaining remain VBG cord-293714-s6ezxi5r 115 28 two two CD cord-293714-s6ezxi5r 115 29 contained contain VBN cord-293714-s6ezxi5r 115 30 streptococci streptococcus NNS cord-293714-s6ezxi5r 115 31 producing produce VBG cord-293714-s6ezxi5r 115 32 streptococcal streptococcal JJ cord-293714-s6ezxi5r 115 33 pyrogenic pyrogenic JJ cord-293714-s6ezxi5r 115 34 exotoxin exotoxin NN cord-293714-s6ezxi5r 115 35 B B NNP cord-293714-s6ezxi5r 115 36 ( ( -LRB- cord-293714-s6ezxi5r 115 37 SPEB SPEB NNP cord-293714-s6ezxi5r 115 38 ) ) -RRB- cord-293714-s6ezxi5r 115 39 and and CC cord-293714-s6ezxi5r 115 40 streptococcal streptococcal JJ cord-293714-s6ezxi5r 115 41 pyrogenic pyrogenic JJ cord-293714-s6ezxi5r 115 42 exotoxin exotoxin NN cord-293714-s6ezxi5r 115 43 C C NNP cord-293714-s6ezxi5r 115 44 ( ( -LRB- cord-293714-s6ezxi5r 115 45 SPEC SPEC NNP cord-293714-s6ezxi5r 115 46 ) ) -RRB- cord-293714-s6ezxi5r 115 47 . . . cord-293714-s6ezxi5r 116 1 Twelve twelve CD cord-293714-s6ezxi5r 116 2 of of IN cord-293714-s6ezxi5r 116 3 the the DT cord-293714-s6ezxi5r 116 4 culture culture NN cord-293714-s6ezxi5r 116 5 - - HYPH cord-293714-s6ezxi5r 116 6 positive positive JJ cord-293714-s6ezxi5r 116 7 patients patient NNS cord-293714-s6ezxi5r 116 8 had have VBD cord-293714-s6ezxi5r 116 9 toxin toxin NN cord-293714-s6ezxi5r 116 10 - - HYPH cord-293714-s6ezxi5r 116 11 producing produce VBG cord-293714-s6ezxi5r 116 12 S. S. NNP cord-293714-s6ezxi5r 116 13 aureus aureus NN cord-293714-s6ezxi5r 116 14 isolated isolate VBN cord-293714-s6ezxi5r 116 15 from from IN cord-293714-s6ezxi5r 116 16 pharyngeal pharyngeal JJ cord-293714-s6ezxi5r 116 17 or or CC cord-293714-s6ezxi5r 116 18 rectal rectal JJ cord-293714-s6ezxi5r 116 19 cultures culture NNS cord-293714-s6ezxi5r 116 20 , , , cord-293714-s6ezxi5r 116 21 thus thus RB cord-293714-s6ezxi5r 116 22 suggesting suggest VBG cord-293714-s6ezxi5r 116 23 the the DT cord-293714-s6ezxi5r 116 24 gastrointestinal gastrointestinal JJ cord-293714-s6ezxi5r 116 25 tract tract NN cord-293714-s6ezxi5r 116 26 as as IN cord-293714-s6ezxi5r 116 27 the the DT cord-293714-s6ezxi5r 116 28 primary primary JJ cord-293714-s6ezxi5r 116 29 entry entry NN cord-293714-s6ezxi5r 116 30 site site NN cord-293714-s6ezxi5r 116 31 . . . cord-293714-s6ezxi5r 117 1 Similar similar JJ cord-293714-s6ezxi5r 117 2 findings finding NNS cord-293714-s6ezxi5r 117 3 of of IN cord-293714-s6ezxi5r 117 4 TSST-1-producing tsst-1-produce VBG cord-293714-s6ezxi5r 117 5 S. S. NNP cord-293714-s6ezxi5r 117 6 aureus aureus NN cord-293714-s6ezxi5r 117 7 and and CC cord-293714-s6ezxi5r 117 8 SPEC spec NN cord-293714-s6ezxi5r 117 9 - - HYPH cord-293714-s6ezxi5r 117 10 producing produce VBG cord-293714-s6ezxi5r 117 11 streptococci streptococcus NNS cord-293714-s6ezxi5r 117 12 in in IN cord-293714-s6ezxi5r 117 13 children child NNS cord-293714-s6ezxi5r 117 14 with with IN cord-293714-s6ezxi5r 117 15 acute acute JJ cord-293714-s6ezxi5r 117 16 KS KS NNP cord-293714-s6ezxi5r 117 17 have have VBP cord-293714-s6ezxi5r 117 18 been be VBN cord-293714-s6ezxi5r 117 19 recently recently RB cord-293714-s6ezxi5r 117 20 published publish VBN cord-293714-s6ezxi5r 117 21 . . . cord-293714-s6ezxi5r 118 1 47 47 CD cord-293714-s6ezxi5r 119 1 The the DT cord-293714-s6ezxi5r 119 2 SA SA NNP cord-293714-s6ezxi5r 119 3 theory theory NN cord-293714-s6ezxi5r 119 4 may may MD cord-293714-s6ezxi5r 119 5 be be VB cord-293714-s6ezxi5r 119 6 supported support VBN cord-293714-s6ezxi5r 119 7 by by IN cord-293714-s6ezxi5r 119 8 anecdotal anecdotal JJ cord-293714-s6ezxi5r 119 9 reports report NNS cord-293714-s6ezxi5r 119 10 of of IN cord-293714-s6ezxi5r 119 11 KS KS NNP cord-293714-s6ezxi5r 119 12 patients patient NNS cord-293714-s6ezxi5r 119 13 with with IN cord-293714-s6ezxi5r 119 14 guttate guttate JJ cord-293714-s6ezxi5r 119 15 psoriasis psoriasis NN cord-293714-s6ezxi5r 119 16 because because IN cord-293714-s6ezxi5r 119 17 it -PRON- PRP cord-293714-s6ezxi5r 119 18 has have VBZ cord-293714-s6ezxi5r 119 19 been be VBN cord-293714-s6ezxi5r 119 20 suggested suggest VBN cord-293714-s6ezxi5r 119 21 that that IN cord-293714-s6ezxi5r 119 22 this this DT cord-293714-s6ezxi5r 119 23 form form NN cord-293714-s6ezxi5r 119 24 of of IN cord-293714-s6ezxi5r 119 25 psoriasis psoriasis NN cord-293714-s6ezxi5r 119 26 is be VBZ cord-293714-s6ezxi5r 119 27 due due JJ cord-293714-s6ezxi5r 119 28 to to IN cord-293714-s6ezxi5r 119 29 toxinmediated toxinmediate VBN cord-293714-s6ezxi5r 119 30 T T NNP cord-293714-s6ezxi5r 119 31 cell cell NN cord-293714-s6ezxi5r 119 32 activation activation NN cord-293714-s6ezxi5r 119 33 . . . cord-293714-s6ezxi5r 120 1 53 53 CD cord-293714-s6ezxi5r 121 1 Furthermore furthermore RB cord-293714-s6ezxi5r 121 2 , , , cord-293714-s6ezxi5r 121 3 a a DT cord-293714-s6ezxi5r 121 4 number number NN cord-293714-s6ezxi5r 121 5 of of IN cord-293714-s6ezxi5r 121 6 studies study NNS cord-293714-s6ezxi5r 121 7 analysing analyse VBG cord-293714-s6ezxi5r 121 8 the the DT cord-293714-s6ezxi5r 121 9 T T NNP cord-293714-s6ezxi5r 121 10 lymphocyte lymphocyte NN cord-293714-s6ezxi5r 121 11 receptor receptor NN cord-293714-s6ezxi5r 121 12 repertoire repertoire NN cord-293714-s6ezxi5r 121 13 and and CC cord-293714-s6ezxi5r 121 14 the the DT cord-293714-s6ezxi5r 121 15 titres titre NNS cord-293714-s6ezxi5r 121 16 of of IN cord-293714-s6ezxi5r 121 17 antibodies antibody NNS cord-293714-s6ezxi5r 121 18 against against IN cord-293714-s6ezxi5r 121 19 selected select VBN cord-293714-s6ezxi5r 121 20 SAs SAs NNP cord-293714-s6ezxi5r 121 21 have have VBP cord-293714-s6ezxi5r 121 22 indirectly indirectly RB cord-293714-s6ezxi5r 121 23 demonstrated demonstrate VBN cord-293714-s6ezxi5r 121 24 that that IN cord-293714-s6ezxi5r 121 25 these these DT cord-293714-s6ezxi5r 121 26 proteins protein NNS cord-293714-s6ezxi5r 121 27 may may MD cord-293714-s6ezxi5r 121 28 be be VB cord-293714-s6ezxi5r 121 29 related relate VBN cord-293714-s6ezxi5r 121 30 to to IN cord-293714-s6ezxi5r 121 31 the the DT cord-293714-s6ezxi5r 121 32 development development NN cord-293714-s6ezxi5r 121 33 of of IN cord-293714-s6ezxi5r 121 34 KS KS NNP cord-293714-s6ezxi5r 121 35 . . . cord-293714-s6ezxi5r 122 1 52,54e56 52,54e56 CD cord-293714-s6ezxi5r 123 1 In in IN cord-293714-s6ezxi5r 123 2 addition addition NN cord-293714-s6ezxi5r 123 3 , , , cord-293714-s6ezxi5r 123 4 Suenaga Suenaga NNP cord-293714-s6ezxi5r 123 5 et et NNP cord-293714-s6ezxi5r 123 6 al al NNP cord-293714-s6ezxi5r 123 7 . . . cord-293714-s6ezxi5r 124 1 examined examine VBD cord-293714-s6ezxi5r 124 2 five five CD cord-293714-s6ezxi5r 124 3 SA SA NNP cord-293714-s6ezxi5r 124 4 genes gene NNS cord-293714-s6ezxi5r 124 5 in in IN cord-293714-s6ezxi5r 124 6 the the DT cord-293714-s6ezxi5r 124 7 stools stool NNS cord-293714-s6ezxi5r 124 8 of of IN cord-293714-s6ezxi5r 124 9 KS KS NNP cord-293714-s6ezxi5r 124 10 patients patient NNS cord-293714-s6ezxi5r 124 11 , , , cord-293714-s6ezxi5r 124 12 febrile febrile JJ cord-293714-s6ezxi5r 124 13 controls control NNS cord-293714-s6ezxi5r 124 14 and and CC cord-293714-s6ezxi5r 124 15 healthy healthy JJ cord-293714-s6ezxi5r 124 16 children child NNS cord-293714-s6ezxi5r 124 17 , , , cord-293714-s6ezxi5r 124 18 57 57 CD cord-293714-s6ezxi5r 124 19 and and CC cord-293714-s6ezxi5r 124 20 found find VBD cord-293714-s6ezxi5r 124 21 at at IN cord-293714-s6ezxi5r 124 22 least least RBS cord-293714-s6ezxi5r 124 23 one one CD cord-293714-s6ezxi5r 124 24 of of IN cord-293714-s6ezxi5r 124 25 the the DT cord-293714-s6ezxi5r 124 26 genes gene NNS cord-293714-s6ezxi5r 124 27 in in IN cord-293714-s6ezxi5r 124 28 42 42 CD cord-293714-s6ezxi5r 124 29 specimens specimen NNS cord-293714-s6ezxi5r 124 30 from from IN cord-293714-s6ezxi5r 124 31 the the DT cord-293714-s6ezxi5r 124 32 patients patient NNS cord-293714-s6ezxi5r 124 33 with with IN cord-293714-s6ezxi5r 124 34 KS KS NNP cord-293714-s6ezxi5r 124 35 ( ( -LRB- cord-293714-s6ezxi5r 124 36 70 70 CD cord-293714-s6ezxi5r 124 37 % % NN cord-293714-s6ezxi5r 124 38 ) ) -RRB- cord-293714-s6ezxi5r 124 39 , , , cord-293714-s6ezxi5r 124 40 in in IN cord-293714-s6ezxi5r 124 41 14 14 CD cord-293714-s6ezxi5r 124 42 from from IN cord-293714-s6ezxi5r 124 43 the the DT cord-293714-s6ezxi5r 124 44 febrile febrile JJ cord-293714-s6ezxi5r 124 45 group group NN cord-293714-s6ezxi5r 124 46 ( ( -LRB- cord-293714-s6ezxi5r 124 47 38.9 38.9 CD cord-293714-s6ezxi5r 124 48 % % NN cord-293714-s6ezxi5r 124 49 ) ) -RRB- cord-293714-s6ezxi5r 124 50 , , , cord-293714-s6ezxi5r 124 51 and and CC cord-293714-s6ezxi5r 124 52 in in IN cord-293714-s6ezxi5r 124 53 seven seven CD cord-293714-s6ezxi5r 124 54 from from IN cord-293714-s6ezxi5r 124 55 the the DT cord-293714-s6ezxi5r 124 56 healthy healthy JJ cord-293714-s6ezxi5r 124 57 group group NN cord-293714-s6ezxi5r 124 58 ( ( -LRB- cord-293714-s6ezxi5r 124 59 26.9 26.9 CD cord-293714-s6ezxi5r 124 60 % % NN cord-293714-s6ezxi5r 124 61 ) ) -RRB- cord-293714-s6ezxi5r 124 62 . . . cord-293714-s6ezxi5r 125 1 The the DT cord-293714-s6ezxi5r 125 2 detection detection NN cord-293714-s6ezxi5r 125 3 rate rate NN cord-293714-s6ezxi5r 125 4 between between IN cord-293714-s6ezxi5r 125 5 subjects subject NNS cord-293714-s6ezxi5r 125 6 with with IN cord-293714-s6ezxi5r 125 7 and and CC cord-293714-s6ezxi5r 125 8 without without IN cord-293714-s6ezxi5r 125 9 KS KS NNP cord-293714-s6ezxi5r 125 10 was be VBD cord-293714-s6ezxi5r 125 11 of of IN cord-293714-s6ezxi5r 125 12 at at RB cord-293714-s6ezxi5r 125 13 least least RBS cord-293714-s6ezxi5r 125 14 one one CD cord-293714-s6ezxi5r 125 15 of of IN cord-293714-s6ezxi5r 125 16 the the DT cord-293714-s6ezxi5r 125 17 5 5 CD cord-293714-s6ezxi5r 125 18 SA SA NNP cord-293714-s6ezxi5r 125 19 genes gene NNS cord-293714-s6ezxi5r 125 20 ( ( -LRB- cord-293714-s6ezxi5r 125 21 p p NN cord-293714-s6ezxi5r 125 22 < < XX cord-293714-s6ezxi5r 125 23 0.001 0.001 CD cord-293714-s6ezxi5r 125 24 ) ) -RRB- cord-293714-s6ezxi5r 125 25 , , , cord-293714-s6ezxi5r 125 26 and and CC cord-293714-s6ezxi5r 125 27 more more JJR cord-293714-s6ezxi5r 125 28 than than IN cord-293714-s6ezxi5r 125 29 two two CD cord-293714-s6ezxi5r 125 30 SA SA NNP cord-293714-s6ezxi5r 125 31 genes gene NNS cord-293714-s6ezxi5r 125 32 were be VBD cord-293714-s6ezxi5r 125 33 significantly significantly RB cord-293714-s6ezxi5r 125 34 different different JJ cord-293714-s6ezxi5r 125 35 ( ( -LRB- cord-293714-s6ezxi5r 125 36 p p NN cord-293714-s6ezxi5r 125 37 Z z NN cord-293714-s6ezxi5r 125 38 0.002 0.002 CD cord-293714-s6ezxi5r 125 39 ) ) -RRB- cord-293714-s6ezxi5r 125 40 , , , cord-293714-s6ezxi5r 125 41 thus thus RB cord-293714-s6ezxi5r 125 42 suggesting suggest VBG cord-293714-s6ezxi5r 125 43 the the DT cord-293714-s6ezxi5r 125 44 direct direct JJ cord-293714-s6ezxi5r 125 45 involvement involvement NN cord-293714-s6ezxi5r 125 46 of of IN cord-293714-s6ezxi5r 125 47 SAs SAs NNP cord-293714-s6ezxi5r 125 48 in in IN cord-293714-s6ezxi5r 125 49 the the DT cord-293714-s6ezxi5r 125 50 development development NN cord-293714-s6ezxi5r 125 51 of of IN cord-293714-s6ezxi5r 125 52 KS KS NNP cord-293714-s6ezxi5r 125 53 . . . cord-293714-s6ezxi5r 126 1 Despite despite IN cord-293714-s6ezxi5r 126 2 the the DT cord-293714-s6ezxi5r 126 3 direct direct JJ cord-293714-s6ezxi5r 126 4 and and CC cord-293714-s6ezxi5r 126 5 indirect indirect JJ cord-293714-s6ezxi5r 126 6 evidence evidence NN cord-293714-s6ezxi5r 126 7 supporting support VBG cord-293714-s6ezxi5r 126 8 the the DT cord-293714-s6ezxi5r 126 9 hypothesis hypothesis NN cord-293714-s6ezxi5r 126 10 that that IN cord-293714-s6ezxi5r 126 11 KS KS NNP cord-293714-s6ezxi5r 126 12 is be VBZ cord-293714-s6ezxi5r 126 13 an an DT cord-293714-s6ezxi5r 126 14 infectious infectious JJ cord-293714-s6ezxi5r 126 15 disease disease NN cord-293714-s6ezxi5r 126 16 , , , cord-293714-s6ezxi5r 126 17 only only RB cord-293714-s6ezxi5r 126 18 " " `` cord-293714-s6ezxi5r 126 19 susceptible susceptible JJ cord-293714-s6ezxi5r 126 20 " " '' cord-293714-s6ezxi5r 126 21 subjects subject NNS cord-293714-s6ezxi5r 126 22 seem seem VBP cord-293714-s6ezxi5r 126 23 to to TO cord-293714-s6ezxi5r 126 24 develop develop VB cord-293714-s6ezxi5r 126 25 it -PRON- PRP cord-293714-s6ezxi5r 126 26 and and CC cord-293714-s6ezxi5r 126 27 genetics genetic NNS cord-293714-s6ezxi5r 126 28 seem seem VBP cord-293714-s6ezxi5r 126 29 to to TO cord-293714-s6ezxi5r 126 30 play play VB cord-293714-s6ezxi5r 126 31 a a DT cord-293714-s6ezxi5r 126 32 role role NN cord-293714-s6ezxi5r 126 33 in in IN cord-293714-s6ezxi5r 126 34 selecting select VBG cord-293714-s6ezxi5r 126 35 the the DT cord-293714-s6ezxi5r 126 36 patients patient NNS cord-293714-s6ezxi5r 126 37 . . . cord-293714-s6ezxi5r 127 1 KS KS NNP cord-293714-s6ezxi5r 127 2 occurs occur VBZ cord-293714-s6ezxi5r 127 3 throughout throughout IN cord-293714-s6ezxi5r 127 4 the the DT cord-293714-s6ezxi5r 127 5 world world NN cord-293714-s6ezxi5r 127 6 , , , cord-293714-s6ezxi5r 127 7 but but CC cord-293714-s6ezxi5r 127 8 is be VBZ cord-293714-s6ezxi5r 127 9 significantly significantly RB cord-293714-s6ezxi5r 127 10 more more RBR cord-293714-s6ezxi5r 127 11 common common JJ cord-293714-s6ezxi5r 127 12 in in IN cord-293714-s6ezxi5r 127 13 some some DT cord-293714-s6ezxi5r 127 14 Asian asian JJ cord-293714-s6ezxi5r 127 15 countries country NNS cord-293714-s6ezxi5r 127 16 , , , cord-293714-s6ezxi5r 127 17 such such JJ cord-293714-s6ezxi5r 127 18 as as IN cord-293714-s6ezxi5r 127 19 Japan Japan NNP cord-293714-s6ezxi5r 127 20 , , , cord-293714-s6ezxi5r 127 21 Korea Korea NNP cord-293714-s6ezxi5r 127 22 and and CC cord-293714-s6ezxi5r 127 23 Taiwan Taiwan NNP cord-293714-s6ezxi5r 127 24 . . . cord-293714-s6ezxi5r 128 1 It -PRON- PRP cord-293714-s6ezxi5r 128 2 has have VBZ cord-293714-s6ezxi5r 128 3 been be VBN cord-293714-s6ezxi5r 128 4 reported report VBN cord-293714-s6ezxi5r 128 5 that that IN cord-293714-s6ezxi5r 128 6 the the DT cord-293714-s6ezxi5r 128 7 annual annual JJ cord-293714-s6ezxi5r 128 8 incidence incidence NN cord-293714-s6ezxi5r 128 9 of of IN cord-293714-s6ezxi5r 128 10 KS KS NNP cord-293714-s6ezxi5r 128 11 in in IN cord-293714-s6ezxi5r 128 12 Japan Japan NNP cord-293714-s6ezxi5r 128 13 in in IN cord-293714-s6ezxi5r 128 14 2009 2009 CD cord-293714-s6ezxi5r 128 15 and and CC cord-293714-s6ezxi5r 128 16 2010 2010 CD cord-293714-s6ezxi5r 128 17 was be VBD cord-293714-s6ezxi5r 128 18 respectively respectively RB cord-293714-s6ezxi5r 128 19 206.2 206.2 CD cord-293714-s6ezxi5r 128 20 and and CC cord-293714-s6ezxi5r 128 21 239.6 239.6 CD cord-293714-s6ezxi5r 128 22 per per IN cord-293714-s6ezxi5r 128 23 100,000 100,000 CD cord-293714-s6ezxi5r 128 24 children child NNS cord-293714-s6ezxi5r 128 25 aged age VBN cord-293714-s6ezxi5r 128 26 0e4 0e4 CD cord-293714-s6ezxi5r 128 27 years year NNS cord-293714-s6ezxi5r 128 28 58 58 CD cord-293714-s6ezxi5r 128 29 ; ; : cord-293714-s6ezxi5r 128 30 on on IN cord-293714-s6ezxi5r 128 31 the the DT cord-293714-s6ezxi5r 128 32 contrary contrary NN cord-293714-s6ezxi5r 128 33 , , , cord-293714-s6ezxi5r 128 34 a a DT cord-293714-s6ezxi5r 128 35 recent recent JJ cord-293714-s6ezxi5r 128 36 analysis analysis NN cord-293714-s6ezxi5r 128 37 found find VBD cord-293714-s6ezxi5r 128 38 that that IN cord-293714-s6ezxi5r 128 39 the the DT cord-293714-s6ezxi5r 128 40 2009 2009 CD cord-293714-s6ezxi5r 128 41 KS KS NNP cord-293714-s6ezxi5r 128 42 - - HYPH cord-293714-s6ezxi5r 128 43 related relate VBN cord-293714-s6ezxi5r 128 44 hospitalisation hospitalisation NN cord-293714-s6ezxi5r 128 45 rate rate NN cord-293714-s6ezxi5r 128 46 in in IN cord-293714-s6ezxi5r 128 47 the the DT cord-293714-s6ezxi5r 128 48 USA USA NNP cord-293714-s6ezxi5r 128 49 was be VBD cord-293714-s6ezxi5r 128 50 19 19 CD cord-293714-s6ezxi5r 128 51 per per IN cord-293714-s6ezxi5r 128 52 100,000 100,000 CD cord-293714-s6ezxi5r 128 53 children child NNS cord-293714-s6ezxi5r 128 54 aged age VBN cord-293714-s6ezxi5r 128 55 < < XX cord-293714-s6ezxi5r 128 56 5 5 CD cord-293714-s6ezxi5r 128 57 years year NNS cord-293714-s6ezxi5r 128 58 , , , cord-293714-s6ezxi5r 128 59 59 59 CD cord-293714-s6ezxi5r 128 60 and and CC cord-293714-s6ezxi5r 128 61 even even RB cord-293714-s6ezxi5r 128 62 lower low JJR cord-293714-s6ezxi5r 128 63 incidence incidence NN cord-293714-s6ezxi5r 128 64 rates rate NNS cord-293714-s6ezxi5r 128 65 have have VBP cord-293714-s6ezxi5r 128 66 been be VBN cord-293714-s6ezxi5r 128 67 calculated calculate VBN cord-293714-s6ezxi5r 128 68 for for IN cord-293714-s6ezxi5r 128 69 a a DT cord-293714-s6ezxi5r 128 70 number number NN cord-293714-s6ezxi5r 128 71 of of IN cord-293714-s6ezxi5r 128 72 European european JJ cord-293714-s6ezxi5r 128 73 countries country NNS cord-293714-s6ezxi5r 128 74 . . . cord-293714-s6ezxi5r 129 1 60e63 60e63 NNP cord-293714-s6ezxi5r 129 2 Theoretically theoretically RB cord-293714-s6ezxi5r 129 3 , , , cord-293714-s6ezxi5r 129 4 various various JJ cord-293714-s6ezxi5r 129 5 factors factor NNS cord-293714-s6ezxi5r 129 6 could could MD cord-293714-s6ezxi5r 129 7 explain explain VB cord-293714-s6ezxi5r 129 8 this this DT cord-293714-s6ezxi5r 129 9 large large JJ cord-293714-s6ezxi5r 129 10 difference difference NN cord-293714-s6ezxi5r 129 11 . . . cord-293714-s6ezxi5r 130 1 The the DT cord-293714-s6ezxi5r 130 2 incidence incidence NN cord-293714-s6ezxi5r 130 3 of of IN cord-293714-s6ezxi5r 130 4 KS KS NNP cord-293714-s6ezxi5r 130 5 is be VBZ cord-293714-s6ezxi5r 130 6 rapidly rapidly RB cord-293714-s6ezxi5r 130 7 increasing increase VBG cord-293714-s6ezxi5r 130 8 throughout throughout IN cord-293714-s6ezxi5r 130 9 the the DT cord-293714-s6ezxi5r 130 10 world world NN cord-293714-s6ezxi5r 130 11 , , , cord-293714-s6ezxi5r 130 12 and and CC cord-293714-s6ezxi5r 130 13 so so RB cord-293714-s6ezxi5r 130 14 surveys survey NNS cord-293714-s6ezxi5r 130 15 carried carry VBN cord-293714-s6ezxi5r 130 16 out out RP cord-293714-s6ezxi5r 130 17 at at IN cord-293714-s6ezxi5r 130 18 different different JJ cord-293714-s6ezxi5r 130 19 times time NNS cord-293714-s6ezxi5r 130 20 may may MD cord-293714-s6ezxi5r 130 21 lead lead VB cord-293714-s6ezxi5r 130 22 to to IN cord-293714-s6ezxi5r 130 23 different different JJ cord-293714-s6ezxi5r 130 24 results result NNS cord-293714-s6ezxi5r 130 25 . . . cord-293714-s6ezxi5r 131 1 Moreover moreover RB cord-293714-s6ezxi5r 131 2 , , , cord-293714-s6ezxi5r 131 3 although although IN cord-293714-s6ezxi5r 131 4 KS KS NNP cord-293714-s6ezxi5r 131 5 is be VBZ cord-293714-s6ezxi5r 131 6 significantly significantly RB cord-293714-s6ezxi5r 131 7 more more RBR cord-293714-s6ezxi5r 131 8 frequent frequent JJ cord-293714-s6ezxi5r 131 9 in in IN cord-293714-s6ezxi5r 131 10 younger young JJR cord-293714-s6ezxi5r 131 11 children child NNS cord-293714-s6ezxi5r 131 12 than than IN cord-293714-s6ezxi5r 131 13 in in IN cord-293714-s6ezxi5r 131 14 older old JJR cord-293714-s6ezxi5r 131 15 children child NNS cord-293714-s6ezxi5r 131 16 , , , cord-293714-s6ezxi5r 131 17 adolescents adolescent NNS cord-293714-s6ezxi5r 131 18 or or CC cord-293714-s6ezxi5r 131 19 adults adult NNS cord-293714-s6ezxi5r 131 20 , , , cord-293714-s6ezxi5r 131 21 its -PRON- PRP$ cord-293714-s6ezxi5r 131 22 frequency frequency NN cord-293714-s6ezxi5r 131 23 in in IN cord-293714-s6ezxi5r 131 24 younger young JJR cord-293714-s6ezxi5r 131 25 patients patient NNS cord-293714-s6ezxi5r 131 26 also also RB cord-293714-s6ezxi5r 131 27 varies vary VBZ cord-293714-s6ezxi5r 131 28 . . . cord-293714-s6ezxi5r 132 1 A a DT cord-293714-s6ezxi5r 132 2 comparison comparison NN cord-293714-s6ezxi5r 132 3 of of IN cord-293714-s6ezxi5r 132 4 the the DT cord-293714-s6ezxi5r 132 5 incidence incidence NN cord-293714-s6ezxi5r 132 6 of of IN cord-293714-s6ezxi5r 132 7 KS KS NNP cord-293714-s6ezxi5r 132 8 in in IN cord-293714-s6ezxi5r 132 9 Northern northern JJ cord-293714-s6ezxi5r 132 10 European European NNP cord-293714-s6ezxi5r 132 11 and and CC cord-293714-s6ezxi5r 132 12 Japan Japan NNP cord-293714-s6ezxi5r 132 13 found find VBD cord-293714-s6ezxi5r 132 14 that that IN cord-293714-s6ezxi5r 132 15 86.4 86.4 CD cord-293714-s6ezxi5r 132 16 % % NN cord-293714-s6ezxi5r 132 17 of of IN cord-293714-s6ezxi5r 132 18 the the DT cord-293714-s6ezxi5r 132 19 Japanese japanese JJ cord-293714-s6ezxi5r 132 20 patients patient NNS cord-293714-s6ezxi5r 132 21 were be VBD cord-293714-s6ezxi5r 132 22 aged age VBN cord-293714-s6ezxi5r 132 23 < < XX cord-293714-s6ezxi5r 132 24 5 5 CD cord-293714-s6ezxi5r 132 25 years year NNS cord-293714-s6ezxi5r 132 26 , , , cord-293714-s6ezxi5r 132 27 but but CC cord-293714-s6ezxi5r 132 28 67.8 67.8 CD cord-293714-s6ezxi5r 132 29 % % NN cord-293714-s6ezxi5r 132 30 of of IN cord-293714-s6ezxi5r 132 31 the the DT cord-293714-s6ezxi5r 132 32 cases case NNS cord-293714-s6ezxi5r 132 33 diagnosed diagnose VBN cord-293714-s6ezxi5r 132 34 in in IN cord-293714-s6ezxi5r 132 35 Norway Norway NNP cord-293714-s6ezxi5r 132 36 , , , cord-293714-s6ezxi5r 132 37 Finland Finland NNP cord-293714-s6ezxi5r 132 38 , , , cord-293714-s6ezxi5r 132 39 Sweden Sweden NNP cord-293714-s6ezxi5r 132 40 and and CC cord-293714-s6ezxi5r 132 41 Denmark Denmark NNP cord-293714-s6ezxi5r 132 42 ( ( -LRB- cord-293714-s6ezxi5r 132 43 p p NN cord-293714-s6ezxi5r 132 44 < < XX cord-293714-s6ezxi5r 132 45 0.001 0.001 CD cord-293714-s6ezxi5r 132 46 ) ) -RRB- cord-293714-s6ezxi5r 132 47 . . . cord-293714-s6ezxi5r 133 1 63 63 CD cord-293714-s6ezxi5r 134 1 The the DT cord-293714-s6ezxi5r 134 2 incidence incidence NN cord-293714-s6ezxi5r 134 3 of of IN cord-293714-s6ezxi5r 134 4 KS KS NNP cord-293714-s6ezxi5r 134 5 in in IN cord-293714-s6ezxi5r 134 6 different different JJ cord-293714-s6ezxi5r 134 7 regions region NNS cord-293714-s6ezxi5r 134 8 may may MD cord-293714-s6ezxi5r 134 9 be be VB cord-293714-s6ezxi5r 134 10 affected affect VBN cord-293714-s6ezxi5r 134 11 by by IN cord-293714-s6ezxi5r 134 12 differences difference NNS cord-293714-s6ezxi5r 134 13 in in IN cord-293714-s6ezxi5r 134 14 surveillance surveillance NN cord-293714-s6ezxi5r 134 15 methods method NNS cord-293714-s6ezxi5r 134 16 , , , cord-293714-s6ezxi5r 134 17 clinical clinical JJ cord-293714-s6ezxi5r 134 18 diagnostic diagnostic JJ cord-293714-s6ezxi5r 134 19 and and CC cord-293714-s6ezxi5r 134 20 treatment treatment NN cord-293714-s6ezxi5r 134 21 practices practice NNS cord-293714-s6ezxi5r 134 22 , , , cord-293714-s6ezxi5r 134 23 physician physician NN cord-293714-s6ezxi5r 134 24 awareness awareness NN cord-293714-s6ezxi5r 134 25 of of IN cord-293714-s6ezxi5r 134 26 KS KS NNP cord-293714-s6ezxi5r 134 27 , , , cord-293714-s6ezxi5r 134 28 and and CC cord-293714-s6ezxi5r 134 29 the the DT cord-293714-s6ezxi5r 134 30 occurrences occurrence NNS cord-293714-s6ezxi5r 134 31 of of IN cord-293714-s6ezxi5r 134 32 KS KS NNP cord-293714-s6ezxi5r 134 33 clusters cluster NNS cord-293714-s6ezxi5r 134 34 or or CC cord-293714-s6ezxi5r 134 35 outbreaks outbreak NNS cord-293714-s6ezxi5r 134 36 . . . cord-293714-s6ezxi5r 135 1 However however RB cord-293714-s6ezxi5r 135 2 , , , cord-293714-s6ezxi5r 135 3 a a DT cord-293714-s6ezxi5r 135 4 global global JJ cord-293714-s6ezxi5r 135 5 evaluation evaluation NN cord-293714-s6ezxi5r 135 6 of of IN cord-293714-s6ezxi5r 135 7 all all PDT cord-293714-s6ezxi5r 135 8 these these DT cord-293714-s6ezxi5r 135 9 factors factor NNS cord-293714-s6ezxi5r 135 10 suggests suggest VBZ cord-293714-s6ezxi5r 135 11 that that IN cord-293714-s6ezxi5r 135 12 they -PRON- PRP cord-293714-s6ezxi5r 135 13 are be VBP cord-293714-s6ezxi5r 135 14 unlikely unlikely JJ cord-293714-s6ezxi5r 135 15 to to TO cord-293714-s6ezxi5r 135 16 be be VB cord-293714-s6ezxi5r 135 17 the the DT cord-293714-s6ezxi5r 135 18 only only JJ cord-293714-s6ezxi5r 135 19 reason reason NN cord-293714-s6ezxi5r 135 20 for for IN cord-293714-s6ezxi5r 135 21 such such PDT cord-293714-s6ezxi5r 135 22 a a DT cord-293714-s6ezxi5r 135 23 striking striking JJ cord-293714-s6ezxi5r 135 24 difference difference NN cord-293714-s6ezxi5r 135 25 . . . cord-293714-s6ezxi5r 136 1 Furthermore furthermore RB cord-293714-s6ezxi5r 136 2 , , , cord-293714-s6ezxi5r 136 3 American american JJ cord-293714-s6ezxi5r 136 4 studies study NNS cord-293714-s6ezxi5r 136 5 have have VBP cord-293714-s6ezxi5r 136 6 clearly clearly RB cord-293714-s6ezxi5r 136 7 shown show VBN cord-293714-s6ezxi5r 136 8 ethnicity ethnicity NN cord-293714-s6ezxi5r 136 9 - - HYPH cord-293714-s6ezxi5r 136 10 related relate VBN cord-293714-s6ezxi5r 136 11 variations variation NNS cord-293714-s6ezxi5r 136 12 in in IN cord-293714-s6ezxi5r 136 13 the the DT cord-293714-s6ezxi5r 136 14 incidence incidence NN cord-293714-s6ezxi5r 136 15 of of IN cord-293714-s6ezxi5r 136 16 KS KS NNP cord-293714-s6ezxi5r 136 17 : : : cord-293714-s6ezxi5r 136 18 in in IN cord-293714-s6ezxi5r 136 19 comparison comparison NN cord-293714-s6ezxi5r 136 20 with with IN cord-293714-s6ezxi5r 136 21 white white JJ cord-293714-s6ezxi5r 136 22 subjects subject NNS cord-293714-s6ezxi5r 136 23 , , , cord-293714-s6ezxi5r 136 24 the the DT cord-293714-s6ezxi5r 136 25 incidence incidence NN cord-293714-s6ezxi5r 136 26 is be VBZ cord-293714-s6ezxi5r 136 27 twice twice RB cord-293714-s6ezxi5r 136 28 as as RB cord-293714-s6ezxi5r 136 29 high high JJ cord-293714-s6ezxi5r 136 30 among among IN cord-293714-s6ezxi5r 136 31 Asians Asians NNPS cord-293714-s6ezxi5r 136 32 and and CC cord-293714-s6ezxi5r 136 33 Pacific Pacific NNP cord-293714-s6ezxi5r 136 34 Islanders Islanders NNPS cord-293714-s6ezxi5r 136 35 , , , cord-293714-s6ezxi5r 136 36 and and CC cord-293714-s6ezxi5r 136 37 about about IN cord-293714-s6ezxi5r 136 38 1.5 1.5 CD cord-293714-s6ezxi5r 136 39 times time NNS cord-293714-s6ezxi5r 136 40 higher high JJR cord-293714-s6ezxi5r 136 41 among among IN cord-293714-s6ezxi5r 136 42 black black JJ cord-293714-s6ezxi5r 136 43 subjects subject NNS cord-293714-s6ezxi5r 136 44 . . . cord-293714-s6ezxi5r 137 1 64 64 CD cord-293714-s6ezxi5r 138 1 Similarly similarly RB cord-293714-s6ezxi5r 138 2 , , , cord-293714-s6ezxi5r 138 3 its -PRON- PRP$ cord-293714-s6ezxi5r 138 4 incidence incidence NN cord-293714-s6ezxi5r 138 5 in in IN cord-293714-s6ezxi5r 138 6 Hawaii Hawaii NNP cord-293714-s6ezxi5r 138 7 ( ( -LRB- cord-293714-s6ezxi5r 138 8 the the DT cord-293714-s6ezxi5r 138 9 state state NN cord-293714-s6ezxi5r 138 10 with with IN cord-293714-s6ezxi5r 138 11 the the DT cord-293714-s6ezxi5r 138 12 highest high JJS cord-293714-s6ezxi5r 138 13 proportion proportion NN cord-293714-s6ezxi5r 138 14 of of IN cord-293714-s6ezxi5r 138 15 Asians Asians NNPS cord-293714-s6ezxi5r 138 16 and and CC cord-293714-s6ezxi5r 138 17 Pacific Pacific NNP cord-293714-s6ezxi5r 138 18 Islanders Islanders NNPS cord-293714-s6ezxi5r 138 19 ) ) -RRB- cord-293714-s6ezxi5r 138 20 is be VBZ cord-293714-s6ezxi5r 138 21 2.5 2.5 CD cord-293714-s6ezxi5r 138 22 times time NNS cord-293714-s6ezxi5r 138 23 higher high JJR cord-293714-s6ezxi5r 138 24 than than IN cord-293714-s6ezxi5r 138 25 that that DT cord-293714-s6ezxi5r 138 26 reported report VBD cord-293714-s6ezxi5r 138 27 for for IN cord-293714-s6ezxi5r 138 28 the the DT cord-293714-s6ezxi5r 138 29 continental continental JJ cord-293714-s6ezxi5r 138 30 USA USA NNP cord-293714-s6ezxi5r 138 31 . . . cord-293714-s6ezxi5r 139 1 65 65 CD cord-293714-s6ezxi5r 140 1 It -PRON- PRP cord-293714-s6ezxi5r 140 2 has have VBZ cord-293714-s6ezxi5r 140 3 also also RB cord-293714-s6ezxi5r 140 4 been be VBN cord-293714-s6ezxi5r 140 5 reported report VBN cord-293714-s6ezxi5r 140 6 that that IN cord-293714-s6ezxi5r 140 7 the the DT cord-293714-s6ezxi5r 140 8 incidence incidence NN cord-293714-s6ezxi5r 140 9 of of IN cord-293714-s6ezxi5r 140 10 KS KS NNP cord-293714-s6ezxi5r 140 11 is be VBZ cord-293714-s6ezxi5r 140 12 6e10 6e10 CD cord-293714-s6ezxi5r 140 13 times time NNS cord-293714-s6ezxi5r 140 14 higher high JJR cord-293714-s6ezxi5r 140 15 among among IN cord-293714-s6ezxi5r 140 16 the the DT cord-293714-s6ezxi5r 140 17 siblings sibling NNS cord-293714-s6ezxi5r 140 18 of of IN cord-293714-s6ezxi5r 140 19 KS KS NNP cord-293714-s6ezxi5r 140 20 patients patient NNS cord-293714-s6ezxi5r 140 21 than than IN cord-293714-s6ezxi5r 140 22 in in IN cord-293714-s6ezxi5r 140 23 the the DT cord-293714-s6ezxi5r 140 24 general general JJ cord-293714-s6ezxi5r 140 25 population population NN cord-293714-s6ezxi5r 140 26 , , , cord-293714-s6ezxi5r 140 27 66 66 CD cord-293714-s6ezxi5r 140 28 and and CC cord-293714-s6ezxi5r 140 29 that that IN cord-293714-s6ezxi5r 140 30 children child NNS cord-293714-s6ezxi5r 140 31 with with IN cord-293714-s6ezxi5r 140 32 KS KS NNP cord-293714-s6ezxi5r 140 33 are be VBP cord-293714-s6ezxi5r 140 34 more more RBR cord-293714-s6ezxi5r 140 35 likely likely JJ cord-293714-s6ezxi5r 140 36 to to TO cord-293714-s6ezxi5r 140 37 have have VB cord-293714-s6ezxi5r 140 38 parents parent NNS cord-293714-s6ezxi5r 140 39 who who WP cord-293714-s6ezxi5r 140 40 have have VBP cord-293714-s6ezxi5r 140 41 had have VBN cord-293714-s6ezxi5r 140 42 the the DT cord-293714-s6ezxi5r 140 43 disease disease NN cord-293714-s6ezxi5r 140 44 . . . cord-293714-s6ezxi5r 141 1 67 67 CD cord-293714-s6ezxi5r 142 1 It -PRON- PRP cord-293714-s6ezxi5r 142 2 has have VBZ cord-293714-s6ezxi5r 142 3 been be VBN cord-293714-s6ezxi5r 142 4 calculated calculate VBN cord-293714-s6ezxi5r 142 5 that that IN cord-293714-s6ezxi5r 142 6 the the DT cord-293714-s6ezxi5r 142 7 inheritability inheritability NN cord-293714-s6ezxi5r 142 8 of of IN cord-293714-s6ezxi5r 142 9 KS KS NNP cord-293714-s6ezxi5r 142 10 ( ( -LRB- cord-293714-s6ezxi5r 142 11 i.e. i.e. FW cord-293714-s6ezxi5r 142 12 the the DT cord-293714-s6ezxi5r 142 13 ratio ratio NN cord-293714-s6ezxi5r 142 14 of of IN cord-293714-s6ezxi5r 142 15 the the DT cord-293714-s6ezxi5r 142 16 incidence incidence NN cord-293714-s6ezxi5r 142 17 of of IN cord-293714-s6ezxi5r 142 18 KS KS NNP cord-293714-s6ezxi5r 142 19 between between IN cord-293714-s6ezxi5r 142 20 siblings sibling NNS cord-293714-s6ezxi5r 142 21 and and CC cord-293714-s6ezxi5r 142 22 the the DT cord-293714-s6ezxi5r 142 23 general general JJ cord-293714-s6ezxi5r 142 24 population population NN cord-293714-s6ezxi5r 142 25 ) ) -RRB- cord-293714-s6ezxi5r 142 26 is be VBZ cord-293714-s6ezxi5r 142 27 only only RB cord-293714-s6ezxi5r 142 28 slightly slightly RB cord-293714-s6ezxi5r 142 29 less less JJR cord-293714-s6ezxi5r 142 30 than than IN cord-293714-s6ezxi5r 142 31 that that DT cord-293714-s6ezxi5r 142 32 of of IN cord-293714-s6ezxi5r 142 33 type type NN cord-293714-s6ezxi5r 142 34 1 1 CD cord-293714-s6ezxi5r 142 35 diabetes diabetes NN cord-293714-s6ezxi5r 142 36 and and CC cord-293714-s6ezxi5r 142 37 about about RB cord-293714-s6ezxi5r 142 38 four four CD cord-293714-s6ezxi5r 142 39 times time NNS cord-293714-s6ezxi5r 142 40 more more JJR cord-293714-s6ezxi5r 142 41 than than IN cord-293714-s6ezxi5r 142 42 that that DT cord-293714-s6ezxi5r 142 43 of of IN cord-293714-s6ezxi5r 142 44 allergic allergic JJ cord-293714-s6ezxi5r 142 45 asthma asthma NN cord-293714-s6ezxi5r 142 46 . . . cord-293714-s6ezxi5r 143 1 68 68 CD cord-293714-s6ezxi5r 144 1 All all DT cord-293714-s6ezxi5r 144 2 of of IN cord-293714-s6ezxi5r 144 3 the the DT cord-293714-s6ezxi5r 144 4 above above JJ cord-293714-s6ezxi5r 144 5 findings finding NNS cord-293714-s6ezxi5r 144 6 strongly strongly RB cord-293714-s6ezxi5r 144 7 suggest suggest VBP cord-293714-s6ezxi5r 144 8 that that IN cord-293714-s6ezxi5r 144 9 genetic genetic JJ cord-293714-s6ezxi5r 144 10 factors factor NNS cord-293714-s6ezxi5r 144 11 play play VBP cord-293714-s6ezxi5r 144 12 a a DT cord-293714-s6ezxi5r 144 13 substantial substantial JJ cord-293714-s6ezxi5r 144 14 role role NN cord-293714-s6ezxi5r 144 15 in in IN cord-293714-s6ezxi5r 144 16 the the DT cord-293714-s6ezxi5r 144 17 occurrence occurrence NN cord-293714-s6ezxi5r 144 18 of of IN cord-293714-s6ezxi5r 144 19 KS KS NNP cord-293714-s6ezxi5r 144 20 , , , cord-293714-s6ezxi5r 144 21 but but CC cord-293714-s6ezxi5r 144 22 studies study NNS cord-293714-s6ezxi5r 144 23 of of IN cord-293714-s6ezxi5r 144 24 the the DT cord-293714-s6ezxi5r 144 25 genetic genetic JJ cord-293714-s6ezxi5r 144 26 characteristics characteristic NNS cord-293714-s6ezxi5r 144 27 of of IN cord-293714-s6ezxi5r 144 28 KS KS NNP cord-293714-s6ezxi5r 144 29 patients patient NNS cord-293714-s6ezxi5r 144 30 have have VBP cord-293714-s6ezxi5r 144 31 not not RB cord-293714-s6ezxi5r 144 32 definitively definitively RB cord-293714-s6ezxi5r 144 33 identified identify VBN cord-293714-s6ezxi5r 144 34 which which WDT cord-293714-s6ezxi5r 144 35 genetic genetic JJ cord-293714-s6ezxi5r 144 36 marker(s marker(s NNP cord-293714-s6ezxi5r 144 37 ) ) -RRB- cord-293714-s6ezxi5r 144 38 may may MD cord-293714-s6ezxi5r 144 39 favour favour VB cord-293714-s6ezxi5r 144 40 or or CC cord-293714-s6ezxi5r 144 41 protect protect VB cord-293714-s6ezxi5r 144 42 humans human NNS cord-293714-s6ezxi5r 144 43 from from IN cord-293714-s6ezxi5r 144 44 developing develop VBG cord-293714-s6ezxi5r 144 45 of of IN cord-293714-s6ezxi5r 144 46 KS KS NNP cord-293714-s6ezxi5r 144 47 , , , cord-293714-s6ezxi5r 144 48 or or CC cord-293714-s6ezxi5r 144 49 regulate regulate VB cord-293714-s6ezxi5r 144 50 its -PRON- PRP$ cord-293714-s6ezxi5r 144 51 clinical clinical JJ cord-293714-s6ezxi5r 144 52 severity severity NN cord-293714-s6ezxi5r 144 53 . . . cord-293714-s6ezxi5r 145 1 Several several JJ cord-293714-s6ezxi5r 145 2 candidate candidate NN cord-293714-s6ezxi5r 145 3 genes gene NNS cord-293714-s6ezxi5r 145 4 , , , cord-293714-s6ezxi5r 145 5 mainly mainly RB cord-293714-s6ezxi5r 145 6 chosen choose VBN cord-293714-s6ezxi5r 145 7 among among IN cord-293714-s6ezxi5r 145 8 those those DT cord-293714-s6ezxi5r 145 9 related relate VBN cord-293714-s6ezxi5r 145 10 to to IN cord-293714-s6ezxi5r 145 11 innate innate JJ cord-293714-s6ezxi5r 145 12 and and CC cord-293714-s6ezxi5r 145 13 acquired acquire VBN cord-293714-s6ezxi5r 145 14 immunity immunity NN cord-293714-s6ezxi5r 145 15 , , , cord-293714-s6ezxi5r 145 16 cardiovascular cardiovascular JJ cord-293714-s6ezxi5r 145 17 function function NN cord-293714-s6ezxi5r 145 18 , , , cord-293714-s6ezxi5r 145 19 and and CC cord-293714-s6ezxi5r 145 20 vascular vascular JJ cord-293714-s6ezxi5r 145 21 remodelling remodelling NN cord-293714-s6ezxi5r 145 22 , , , cord-293714-s6ezxi5r 145 23 have have VBP cord-293714-s6ezxi5r 145 24 been be VBN cord-293714-s6ezxi5r 145 25 tested test VBN cord-293714-s6ezxi5r 145 26 in in IN cord-293714-s6ezxi5r 145 27 patients patient NNS cord-293714-s6ezxi5r 145 28 with with IN cord-293714-s6ezxi5r 145 29 KS KS NNP cord-293714-s6ezxi5r 145 30 ( ( -LRB- cord-293714-s6ezxi5r 145 31 Table Table NNP cord-293714-s6ezxi5r 145 32 3 3 CD cord-293714-s6ezxi5r 145 33 ) ) -RRB- cord-293714-s6ezxi5r 145 34 . . . cord-293714-s6ezxi5r 146 1 69e117 69e117 NNP cord-293714-s6ezxi5r 147 1 Results result NNS cord-293714-s6ezxi5r 147 2 were be VBD cord-293714-s6ezxi5r 147 3 frequently frequently RB cord-293714-s6ezxi5r 147 4 negative negative JJ cord-293714-s6ezxi5r 147 5 or or CC cord-293714-s6ezxi5r 147 6 conflicting conflicting JJ cord-293714-s6ezxi5r 147 7 , , , cord-293714-s6ezxi5r 147 8 particularly particularly RB cord-293714-s6ezxi5r 147 9 when when WRB cord-293714-s6ezxi5r 147 10 the the DT cord-293714-s6ezxi5r 147 11 studies study NNS cord-293714-s6ezxi5r 147 12 enrolled enrol VBD cord-293714-s6ezxi5r 147 13 a a DT cord-293714-s6ezxi5r 147 14 limited limited JJ cord-293714-s6ezxi5r 147 15 number number NN cord-293714-s6ezxi5r 147 16 of of IN cord-293714-s6ezxi5r 147 17 patients patient NNS cord-293714-s6ezxi5r 147 18 and and CC cord-293714-s6ezxi5r 147 19 were be VBD cord-293714-s6ezxi5r 147 20 carried carry VBN cord-293714-s6ezxi5r 147 21 out out RP cord-293714-s6ezxi5r 147 22 in in IN cord-293714-s6ezxi5r 147 23 populations population NNS cord-293714-s6ezxi5r 147 24 with with IN cord-293714-s6ezxi5r 147 25 significant significant JJ cord-293714-s6ezxi5r 147 26 racial racial JJ cord-293714-s6ezxi5r 147 27 differences difference NNS cord-293714-s6ezxi5r 147 28 that that WDT cord-293714-s6ezxi5r 147 29 impact impact VBP cord-293714-s6ezxi5r 147 30 the the DT cord-293714-s6ezxi5r 147 31 allele allele NN cord-293714-s6ezxi5r 147 32 frequency frequency NN cord-293714-s6ezxi5r 147 33 of of IN cord-293714-s6ezxi5r 147 34 some some DT cord-293714-s6ezxi5r 147 35 of of IN cord-293714-s6ezxi5r 147 36 the the DT cord-293714-s6ezxi5r 147 37 single single JJ cord-293714-s6ezxi5r 147 38 nucleotide nucleotide JJ cord-293714-s6ezxi5r 147 39 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 147 40 ( ( -LRB- cord-293714-s6ezxi5r 147 41 SNPs SNPs NNP cord-293714-s6ezxi5r 147 42 ) ) -RRB- cord-293714-s6ezxi5r 147 43 analysed analyse VBD cord-293714-s6ezxi5r 147 44 in in IN cord-293714-s6ezxi5r 147 45 the the DT cord-293714-s6ezxi5r 147 46 studies study NNS cord-293714-s6ezxi5r 147 47 . . . cord-293714-s6ezxi5r 148 1 Good good JJ cord-293714-s6ezxi5r 148 2 example example NN cord-293714-s6ezxi5r 148 3 at at IN cord-293714-s6ezxi5r 148 4 this this DT cord-293714-s6ezxi5r 148 5 regard regard NN cord-293714-s6ezxi5r 148 6 are be VBP cord-293714-s6ezxi5r 148 7 the the DT cord-293714-s6ezxi5r 148 8 data datum NNS cord-293714-s6ezxi5r 148 9 collected collect VBN cord-293714-s6ezxi5r 148 10 on on IN cord-293714-s6ezxi5r 148 11 the the DT cord-293714-s6ezxi5r 148 12 role role NN cord-293714-s6ezxi5r 148 13 of of IN cord-293714-s6ezxi5r 148 14 matrix matrix NN cord-293714-s6ezxi5r 148 15 metalloproteinases metalloproteinase NNS cord-293714-s6ezxi5r 148 16 ( ( -LRB- cord-293714-s6ezxi5r 148 17 MMPs MMPs NNP cord-293714-s6ezxi5r 148 18 ) ) -RRB- cord-293714-s6ezxi5r 148 19 , , , cord-293714-s6ezxi5r 148 20 Fc Fc NNP cord-293714-s6ezxi5r 148 21 gamma gamma NN cord-293714-s6ezxi5r 148 22 receptors receptor NNS cord-293714-s6ezxi5r 148 23 ( ( -LRB- cord-293714-s6ezxi5r 148 24 FCGR FCGR NNP cord-293714-s6ezxi5r 148 25 ) ) -RRB- cord-293714-s6ezxi5r 148 26 and and CC cord-293714-s6ezxi5r 148 27 of of IN cord-293714-s6ezxi5r 148 28 CD40 CD40 NNP cord-293714-s6ezxi5r 148 29 ligand ligand NN cord-293714-s6ezxi5r 148 30 SNPs snp NNS cord-293714-s6ezxi5r 148 31 in in IN cord-293714-s6ezxi5r 148 32 conditioning conditioning NN cord-293714-s6ezxi5r 148 33 susceptibility susceptibility NN cord-293714-s6ezxi5r 148 34 , , , cord-293714-s6ezxi5r 148 35 evolution evolution NN cord-293714-s6ezxi5r 148 36 and and CC cord-293714-s6ezxi5r 148 37 outcome outcome NN cord-293714-s6ezxi5r 148 38 of of IN cord-293714-s6ezxi5r 148 39 KS KS NNP cord-293714-s6ezxi5r 148 40 . . . cord-293714-s6ezxi5r 149 1 MMPs mmp NNS cord-293714-s6ezxi5r 149 2 play play VBP cord-293714-s6ezxi5r 149 3 an an DT cord-293714-s6ezxi5r 149 4 important important JJ cord-293714-s6ezxi5r 149 5 role role NN cord-293714-s6ezxi5r 149 6 in in IN cord-293714-s6ezxi5r 149 7 processes process NNS cord-293714-s6ezxi5r 149 8 that that WDT cord-293714-s6ezxi5r 149 9 degrade degrade VBP cord-293714-s6ezxi5r 149 10 extracellular extracellular JJ cord-293714-s6ezxi5r 149 11 matrices matrix NNS cord-293714-s6ezxi5r 149 12 . . . cord-293714-s6ezxi5r 150 1 Their -PRON- PRP$ cord-293714-s6ezxi5r 150 2 activity activity NN cord-293714-s6ezxi5r 150 3 is be VBZ cord-293714-s6ezxi5r 150 4 controlled control VBN cord-293714-s6ezxi5r 150 5 by by IN cord-293714-s6ezxi5r 150 6 specific specific JJ cord-293714-s6ezxi5r 150 7 inhibitors inhibitor NNS cord-293714-s6ezxi5r 150 8 ( ( -LRB- cord-293714-s6ezxi5r 150 9 TIMPs TIMPs NNP cord-293714-s6ezxi5r 150 10 ) ) -RRB- cord-293714-s6ezxi5r 150 11 and and CC cord-293714-s6ezxi5r 150 12 imbalances imbalance NNS cord-293714-s6ezxi5r 150 13 between between IN cord-293714-s6ezxi5r 150 14 MMPs mmp NNS cord-293714-s6ezxi5r 150 15 and and CC cord-293714-s6ezxi5r 150 16 TIMPs timp NNS cord-293714-s6ezxi5r 150 17 are be VBP cord-293714-s6ezxi5r 150 18 associated associate VBN cord-293714-s6ezxi5r 150 19 with with IN cord-293714-s6ezxi5r 150 20 several several JJ cord-293714-s6ezxi5r 150 21 pathological pathological JJ cord-293714-s6ezxi5r 150 22 conditions condition NNS cord-293714-s6ezxi5r 150 23 , , , cord-293714-s6ezxi5r 150 24 including include VBG cord-293714-s6ezxi5r 150 25 vascular vascular JJ cord-293714-s6ezxi5r 150 26 aneurysm aneurysm NN cord-293714-s6ezxi5r 150 27 . . . cord-293714-s6ezxi5r 151 1 Association Association NNP cord-293714-s6ezxi5r 151 2 of of IN cord-293714-s6ezxi5r 151 3 increased increase VBD cord-293714-s6ezxi5r 152 1 MMP9 MMP9 NNP cord-293714-s6ezxi5r 152 2 / / SYM cord-293714-s6ezxi5r 152 3 TIMP2 TIMP2 NNS cord-293714-s6ezxi5r 152 4 and and CC cord-293714-s6ezxi5r 153 1 MMP3/ MMP3/ NNP cord-293714-s6ezxi5r 154 1 TIMP1 TIMP1 NNP cord-293714-s6ezxi5r 154 2 ratios ratio NNS cord-293714-s6ezxi5r 154 3 with with IN cord-293714-s6ezxi5r 154 4 risk risk NN cord-293714-s6ezxi5r 154 5 of of IN cord-293714-s6ezxi5r 154 6 coronary coronary JJ cord-293714-s6ezxi5r 154 7 artery artery NN cord-293714-s6ezxi5r 154 8 lesions lesion NNS cord-293714-s6ezxi5r 154 9 was be VBD cord-293714-s6ezxi5r 154 10 found find VBN cord-293714-s6ezxi5r 154 11 in in IN cord-293714-s6ezxi5r 154 12 Japanese japanese JJ cord-293714-s6ezxi5r 154 13 children child NNS cord-293714-s6ezxi5r 154 14 . . . cord-293714-s6ezxi5r 155 1 95 95 CD cord-293714-s6ezxi5r 156 1 On on IN cord-293714-s6ezxi5r 156 2 the the DT cord-293714-s6ezxi5r 156 3 contrary contrary NN cord-293714-s6ezxi5r 156 4 , , , cord-293714-s6ezxi5r 156 5 no no DT cord-293714-s6ezxi5r 156 6 association association NN cord-293714-s6ezxi5r 156 7 was be VBD cord-293714-s6ezxi5r 156 8 found find VBN cord-293714-s6ezxi5r 156 9 between between IN cord-293714-s6ezxi5r 156 10 SNP SNP NNP cord-293714-s6ezxi5r 156 11 of of IN cord-293714-s6ezxi5r 156 12 MMP-3 MMP-3 NNP cord-293714-s6ezxi5r 156 13 in in IN cord-293714-s6ezxi5r 156 14 the the DT cord-293714-s6ezxi5r 156 15 Korean korean JJ cord-293714-s6ezxi5r 156 16 population population NN cord-293714-s6ezxi5r 156 17 . . . cord-293714-s6ezxi5r 157 1 96 96 CD cord-293714-s6ezxi5r 158 1 Debated debate VBN cord-293714-s6ezxi5r 158 2 is be VBZ cord-293714-s6ezxi5r 158 3 also also RB cord-293714-s6ezxi5r 158 4 the the DT cord-293714-s6ezxi5r 158 5 role role NN cord-293714-s6ezxi5r 158 6 of of IN cord-293714-s6ezxi5r 158 7 CD40L cd40l NN cord-293714-s6ezxi5r 158 8 , , , cord-293714-s6ezxi5r 158 9 a a DT cord-293714-s6ezxi5r 158 10 transmembrane transmembrane NN cord-293714-s6ezxi5r 158 11 protein protein NN cord-293714-s6ezxi5r 158 12 that that WDT cord-293714-s6ezxi5r 158 13 engages engage VBZ cord-293714-s6ezxi5r 158 14 with with IN cord-293714-s6ezxi5r 158 15 CD40 CD40 NNP cord-293714-s6ezxi5r 158 16 and and CC cord-293714-s6ezxi5r 158 17 transduces transduce NNS cord-293714-s6ezxi5r 158 18 signals signal NNS cord-293714-s6ezxi5r 158 19 related relate VBN cord-293714-s6ezxi5r 158 20 to to IN cord-293714-s6ezxi5r 158 21 cell cell NN cord-293714-s6ezxi5r 158 22 activation activation NN cord-293714-s6ezxi5r 158 23 and and CC cord-293714-s6ezxi5r 158 24 development development NN cord-293714-s6ezxi5r 158 25 because because IN cord-293714-s6ezxi5r 158 26 a a DT cord-293714-s6ezxi5r 158 27 strict strict JJ cord-293714-s6ezxi5r 158 28 association association NN cord-293714-s6ezxi5r 158 29 between between IN cord-293714-s6ezxi5r 158 30 SNPs SNPs NNPS cord-293714-s6ezxi5r 158 31 and and CC cord-293714-s6ezxi5r 158 32 development development NN cord-293714-s6ezxi5r 158 33 and and CC cord-293714-s6ezxi5r 158 34 severity severity NN cord-293714-s6ezxi5r 158 35 of of IN cord-293714-s6ezxi5r 158 36 KS KS NNP cord-293714-s6ezxi5r 158 37 was be VBD cord-293714-s6ezxi5r 158 38 demonstrated demonstrate VBN cord-293714-s6ezxi5r 158 39 in in IN cord-293714-s6ezxi5r 158 40 the the DT cord-293714-s6ezxi5r 158 41 Japanese japanese JJ cord-293714-s6ezxi5r 158 42 patients patient NNS cord-293714-s6ezxi5r 158 43 77 77 CD cord-293714-s6ezxi5r 158 44 but but CC cord-293714-s6ezxi5r 158 45 not not RB cord-293714-s6ezxi5r 158 46 in in IN cord-293714-s6ezxi5r 158 47 the the DT cord-293714-s6ezxi5r 158 48 Taiwanese taiwanese JJ cord-293714-s6ezxi5r 158 49 population population NN cord-293714-s6ezxi5r 158 50 . . . cord-293714-s6ezxi5r 159 1 78 78 CD cord-293714-s6ezxi5r 160 1 However however RB cord-293714-s6ezxi5r 160 2 , , , cord-293714-s6ezxi5r 160 3 in in IN cord-293714-s6ezxi5r 160 4 some some DT cord-293714-s6ezxi5r 160 5 studies study NNS cord-293714-s6ezxi5r 160 6 more more RBR cord-293714-s6ezxi5r 160 7 convincing convincing JJ cord-293714-s6ezxi5r 160 8 results result NNS cord-293714-s6ezxi5r 160 9 were be VBD cord-293714-s6ezxi5r 160 10 found find VBN cord-293714-s6ezxi5r 160 11 particularly particularly RB cord-293714-s6ezxi5r 160 12 when when WRB cord-293714-s6ezxi5r 160 13 they -PRON- PRP cord-293714-s6ezxi5r 160 14 could could MD cord-293714-s6ezxi5r 160 15 evidence evidence VB cord-293714-s6ezxi5r 160 16 that that IN cord-293714-s6ezxi5r 160 17 the the DT cord-293714-s6ezxi5r 160 18 same same JJ cord-293714-s6ezxi5r 160 19 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 160 20 were be VBD cord-293714-s6ezxi5r 160 21 present present JJ cord-293714-s6ezxi5r 160 22 in in IN cord-293714-s6ezxi5r 160 23 populations population NNS cord-293714-s6ezxi5r 160 24 with with IN cord-293714-s6ezxi5r 160 25 different different JJ cord-293714-s6ezxi5r 160 26 racial racial JJ cord-293714-s6ezxi5r 160 27 characteristics characteristic NNS cord-293714-s6ezxi5r 160 28 . . . cord-293714-s6ezxi5r 161 1 Onouchi Onouchi NNP cord-293714-s6ezxi5r 161 2 et et NNP cord-293714-s6ezxi5r 161 3 al al NNP cord-293714-s6ezxi5r 161 4 . . NNP cord-293714-s6ezxi5r 161 5 reported report VBD cord-293714-s6ezxi5r 161 6 that that IN cord-293714-s6ezxi5r 161 7 multiple multiple JJ cord-293714-s6ezxi5r 161 8 variants variant NNS cord-293714-s6ezxi5r 161 9 in in IN cord-293714-s6ezxi5r 161 10 the the DT cord-293714-s6ezxi5r 161 11 caspase-3 caspase-3 NNP cord-293714-s6ezxi5r 161 12 gene gene NN cord-293714-s6ezxi5r 161 13 ( ( -LRB- cord-293714-s6ezxi5r 161 14 CASP3 CASP3 NNP cord-293714-s6ezxi5r 161 15 ) ) -RRB- cord-293714-s6ezxi5r 161 16 that that WDT cord-293714-s6ezxi5r 161 17 were be VBD cord-293714-s6ezxi5r 161 18 in in IN cord-293714-s6ezxi5r 161 19 linkage linkage NN cord-293714-s6ezxi5r 161 20 disequilibrium disequilibrium NN cord-293714-s6ezxi5r 161 21 conferred confer VBD cord-293714-s6ezxi5r 161 22 susceptibility susceptibility NN cord-293714-s6ezxi5r 161 23 to to IN cord-293714-s6ezxi5r 161 24 KS KS NNP cord-293714-s6ezxi5r 161 25 in in IN cord-293714-s6ezxi5r 161 26 both both CC cord-293714-s6ezxi5r 161 27 Japanese japanese JJ cord-293714-s6ezxi5r 161 28 and and CC cord-293714-s6ezxi5r 161 29 US US NNP cord-293714-s6ezxi5r 161 30 subjects subject NNS cord-293714-s6ezxi5r 161 31 of of IN cord-293714-s6ezxi5r 161 32 European european JJ cord-293714-s6ezxi5r 161 33 ancestry ancestry NN cord-293714-s6ezxi5r 161 34 . . . cord-293714-s6ezxi5r 162 1 73 73 CD cord-293714-s6ezxi5r 163 1 These these DT cord-293714-s6ezxi5r 163 2 authors author NNS cord-293714-s6ezxi5r 163 3 found find VBD cord-293714-s6ezxi5r 163 4 that that IN cord-293714-s6ezxi5r 163 5 a a DT cord-293714-s6ezxi5r 163 6 G g NN cord-293714-s6ezxi5r 163 7 to to IN cord-293714-s6ezxi5r 163 8 A a DT cord-293714-s6ezxi5r 163 9 substitution substitution NN cord-293714-s6ezxi5r 163 10 of of IN cord-293714-s6ezxi5r 163 11 one one CD cord-293714-s6ezxi5r 163 12 commonly commonly RB cord-293714-s6ezxi5r 163 13 associated associate VBD cord-293714-s6ezxi5r 163 14 SNP SNP NNP cord-293714-s6ezxi5r 163 15 located locate VBN cord-293714-s6ezxi5r 163 16 in in IN cord-293714-s6ezxi5r 163 17 the the DT cord-293714-s6ezxi5r 163 18 5 5 CD cord-293714-s6ezxi5r 163 19 0 0 CD cord-293714-s6ezxi5r 163 20 untranslated untranslated JJ cord-293714-s6ezxi5r 163 21 region region NN cord-293714-s6ezxi5r 163 22 of of IN cord-293714-s6ezxi5r 163 23 CASP3 CASP3 NNP cord-293714-s6ezxi5r 164 1 ( ( -LRB- cord-293714-s6ezxi5r 164 2 rs72689236 rs72689236 NN cord-293714-s6ezxi5r 164 3 ; ; : cord-293714-s6ezxi5r 164 4 p p NN cord-293714-s6ezxi5r 164 5 Z z NN cord-293714-s6ezxi5r 164 6 4.2 4.2 CD cord-293714-s6ezxi5r 164 7 Â â CD cord-293714-s6ezxi5r 164 8 10 10 CD cord-293714-s6ezxi5r 164 9 À8 à8 CD cord-293714-s6ezxi5r 164 10 in in IN cord-293714-s6ezxi5r 164 11 the the DT cord-293714-s6ezxi5r 164 12 Japanese japanese JJ cord-293714-s6ezxi5r 164 13 and and CC cord-293714-s6ezxi5r 164 14 p p NN cord-293714-s6ezxi5r 164 15 Z z NN cord-293714-s6ezxi5r 164 16 3.7 3.7 CD cord-293714-s6ezxi5r 164 17 Â â CD cord-293714-s6ezxi5r 164 18 10 10 CD cord-293714-s6ezxi5r 164 19 À3 à3 CD cord-293714-s6ezxi5r 164 20 in in IN cord-293714-s6ezxi5r 164 21 the the DT cord-293714-s6ezxi5r 164 22 European European NNP cord-293714-s6ezxi5r 164 23 Americans Americans NNPS cord-293714-s6ezxi5r 164 24 ) ) -RRB- cord-293714-s6ezxi5r 164 25 abolished abolish VBD cord-293714-s6ezxi5r 164 26 binding binding NN cord-293714-s6ezxi5r 164 27 of of IN cord-293714-s6ezxi5r 164 28 nuclear nuclear JJ cord-293714-s6ezxi5r 164 29 factor factor NN cord-293714-s6ezxi5r 164 30 of of IN cord-293714-s6ezxi5r 164 31 activated activate VBN cord-293714-s6ezxi5r 164 32 T T NNP cord-293714-s6ezxi5r 164 33 cells cell NNS cord-293714-s6ezxi5r 164 34 to to IN cord-293714-s6ezxi5r 164 35 the the DT cord-293714-s6ezxi5r 164 36 DNA dna NN cord-293714-s6ezxi5r 164 37 sequence sequence NN cord-293714-s6ezxi5r 164 38 surrounding surround VBG cord-293714-s6ezxi5r 164 39 the the DT cord-293714-s6ezxi5r 164 40 SNP SNP NNP cord-293714-s6ezxi5r 164 41 suggesting suggest VBG cord-293714-s6ezxi5r 164 42 that that IN cord-293714-s6ezxi5r 164 43 altered alter VBD cord-293714-s6ezxi5r 164 44 CASP3 CASP3 NNP cord-293714-s6ezxi5r 164 45 expression expression NN cord-293714-s6ezxi5r 164 46 in in IN cord-293714-s6ezxi5r 164 47 immune immune JJ cord-293714-s6ezxi5r 164 48 effecter effecter NN cord-293714-s6ezxi5r 164 49 cells cell NNS cord-293714-s6ezxi5r 164 50 influences influence VBZ cord-293714-s6ezxi5r 164 51 susceptibility susceptibility NN cord-293714-s6ezxi5r 164 52 to to IN cord-293714-s6ezxi5r 164 53 KS KS NNP cord-293714-s6ezxi5r 164 54 . . . cord-293714-s6ezxi5r 165 1 Interesting interesting JJ cord-293714-s6ezxi5r 165 2 results result NNS cord-293714-s6ezxi5r 165 3 were be VBD cord-293714-s6ezxi5r 165 4 also also RB cord-293714-s6ezxi5r 165 5 reported report VBN cord-293714-s6ezxi5r 165 6 by by IN cord-293714-s6ezxi5r 165 7 Shimizu Shimizu NNP cord-293714-s6ezxi5r 165 8 et et NNP cord-293714-s6ezxi5r 165 9 al al NNP cord-293714-s6ezxi5r 165 10 . . . cord-293714-s6ezxi5r 166 1 that that DT cord-293714-s6ezxi5r 166 2 investigated investigate VBD cord-293714-s6ezxi5r 166 3 genetic genetic JJ cord-293714-s6ezxi5r 166 4 variation variation NN cord-293714-s6ezxi5r 166 5 in in IN cord-293714-s6ezxi5r 166 6 15 15 CD cord-293714-s6ezxi5r 166 7 genes gene NNS cord-293714-s6ezxi5r 166 8 belonging belong VBG cord-293714-s6ezxi5r 166 9 to to IN cord-293714-s6ezxi5r 166 10 the the DT cord-293714-s6ezxi5r 166 11 TGF TGF NNP cord-293714-s6ezxi5r 166 12 - - HYPH cord-293714-s6ezxi5r 166 13 B B NNP cord-293714-s6ezxi5r 166 14 pathway pathway NN cord-293714-s6ezxi5r 166 15 in in IN cord-293714-s6ezxi5r 166 16 a a DT cord-293714-s6ezxi5r 166 17 total total NN cord-293714-s6ezxi5r 166 18 of of IN cord-293714-s6ezxi5r 166 19 771 771 CD cord-293714-s6ezxi5r 166 20 KD KD NNP cord-293714-s6ezxi5r 166 21 subjects subject NNS cord-293714-s6ezxi5r 166 22 of of IN cord-293714-s6ezxi5r 166 23 mainly mainly JJ cord-293714-s6ezxi5r 166 24 European european JJ cord-293714-s6ezxi5r 166 25 descent descent NN cord-293714-s6ezxi5r 166 26 from from IN cord-293714-s6ezxi5r 166 27 the the DT cord-293714-s6ezxi5r 166 28 United United NNP cord-293714-s6ezxi5r 166 29 States States NNP cord-293714-s6ezxi5r 166 30 , , , cord-293714-s6ezxi5r 166 31 the the DT cord-293714-s6ezxi5r 166 32 United United NNP cord-293714-s6ezxi5r 166 33 Kingdom Kingdom NNP cord-293714-s6ezxi5r 166 34 , , , cord-293714-s6ezxi5r 166 35 Australia Australia NNP cord-293714-s6ezxi5r 166 36 , , , cord-293714-s6ezxi5r 166 37 and and CC cord-293714-s6ezxi5r 166 38 the the DT cord-293714-s6ezxi5r 166 39 Netherlands Netherlands NNP cord-293714-s6ezxi5r 166 40 . . . cord-293714-s6ezxi5r 167 1 101 101 CD cord-293714-s6ezxi5r 167 2 Genetic genetic JJ cord-293714-s6ezxi5r 167 3 variants variant NNS cord-293714-s6ezxi5r 167 4 in in IN cord-293714-s6ezxi5r 167 5 TGFB2 TGFB2 NNS cord-293714-s6ezxi5r 167 6 , , , cord-293714-s6ezxi5r 167 7 TGFBR2 TGFBR2 NNP cord-293714-s6ezxi5r 167 8 , , , cord-293714-s6ezxi5r 167 9 and and CC cord-293714-s6ezxi5r 167 10 SMAD3 SMAD3 NNP cord-293714-s6ezxi5r 167 11 and and CC cord-293714-s6ezxi5r 167 12 their -PRON- PRP$ cord-293714-s6ezxi5r 167 13 haplotypes haplotype NNS cord-293714-s6ezxi5r 167 14 were be VBD cord-293714-s6ezxi5r 167 15 consistently consistently RB cord-293714-s6ezxi5r 167 16 and and CC cord-293714-s6ezxi5r 167 17 reproducibly reproducibly RB cord-293714-s6ezxi5r 167 18 associated associate VBN cord-293714-s6ezxi5r 167 19 with with IN cord-293714-s6ezxi5r 167 20 KS KS NNP cord-293714-s6ezxi5r 167 21 susceptibility susceptibility NN cord-293714-s6ezxi5r 167 22 , , , cord-293714-s6ezxi5r 167 23 coronary coronary JJ cord-293714-s6ezxi5r 167 24 artery artery NN cord-293714-s6ezxi5r 167 25 aneurysm aneurysm NN cord-293714-s6ezxi5r 167 26 formation formation NN cord-293714-s6ezxi5r 167 27 , , , cord-293714-s6ezxi5r 167 28 aortic aortic JJ cord-293714-s6ezxi5r 167 29 root root NN cord-293714-s6ezxi5r 167 30 dilatation dilatation NN cord-293714-s6ezxi5r 167 31 , , , cord-293714-s6ezxi5r 167 32 and and CC cord-293714-s6ezxi5r 167 33 intravenous intravenous JJ cord-293714-s6ezxi5r 167 34 immunoglobulin immunoglobulin NN cord-293714-s6ezxi5r 167 35 treatment treatment NN cord-293714-s6ezxi5r 167 36 response response NN cord-293714-s6ezxi5r 167 37 in in IN cord-293714-s6ezxi5r 167 38 different different JJ cord-293714-s6ezxi5r 167 39 cohorts cohort NNS cord-293714-s6ezxi5r 167 40 . . . cord-293714-s6ezxi5r 168 1 A a DT cord-293714-s6ezxi5r 168 2 SMAD3 smad3 NN cord-293714-s6ezxi5r 168 3 haplotype haplotype NN cord-293714-s6ezxi5r 168 4 associated associate VBN cord-293714-s6ezxi5r 168 5 with with IN cord-293714-s6ezxi5r 168 6 KS KS NNP cord-293714-s6ezxi5r 168 7 susceptibility susceptibility NN cord-293714-s6ezxi5r 168 8 replicated replicate VBN cord-293714-s6ezxi5r 168 9 in in IN cord-293714-s6ezxi5r 168 10 2 2 CD cord-293714-s6ezxi5r 168 11 independent independent JJ cord-293714-s6ezxi5r 168 12 cohorts cohort NNS cord-293714-s6ezxi5r 168 13 and and CC cord-293714-s6ezxi5r 168 14 an an DT cord-293714-s6ezxi5r 168 15 intronic intronic JJ cord-293714-s6ezxi5r 168 16 single single JJ cord-293714-s6ezxi5r 168 17 nucleotide nucleotide JJ cord-293714-s6ezxi5r 168 18 polymorphism polymorphism NN cord-293714-s6ezxi5r 168 19 in in IN cord-293714-s6ezxi5r 168 20 a a DT cord-293714-s6ezxi5r 168 21 separate separate JJ cord-293714-s6ezxi5r 168 22 haplotype haplotype NN cord-293714-s6ezxi5r 168 23 block block NN cord-293714-s6ezxi5r 168 24 was be VBD cord-293714-s6ezxi5r 168 25 also also RB cord-293714-s6ezxi5r 168 26 strongly strongly RB cord-293714-s6ezxi5r 168 27 associated associate VBN cord-293714-s6ezxi5r 168 28 ( ( -LRB- cord-293714-s6ezxi5r 168 29 A a NN cord-293714-s6ezxi5r 168 30 / / SYM cord-293714-s6ezxi5r 168 31 G g NN cord-293714-s6ezxi5r 168 32 , , , cord-293714-s6ezxi5r 168 33 rs4776338 rs4776338 JJ cord-293714-s6ezxi5r 168 34 ; ; : cord-293714-s6ezxi5r 168 35 p p NN cord-293714-s6ezxi5r 168 36 Z z NN cord-293714-s6ezxi5r 168 37 0.000022 0.000022 CD cord-293714-s6ezxi5r 168 38 ; ; : cord-293714-s6ezxi5r 168 39 OR or CC cord-293714-s6ezxi5r 168 40 , , , cord-293714-s6ezxi5r 168 41 1.50 1.50 CD cord-293714-s6ezxi5r 168 42 ; ; : cord-293714-s6ezxi5r 168 43 95 95 CD cord-293714-s6ezxi5r 168 44 % % NN cord-293714-s6ezxi5r 168 45 CI CI NNP cord-293714-s6ezxi5r 168 46 , , , cord-293714-s6ezxi5r 168 47 1.25e1.81 1.25e1.81 CD cord-293714-s6ezxi5r 168 48 ) ) -RRB- cord-293714-s6ezxi5r 168 49 . . . cord-293714-s6ezxi5r 169 1 Pathway pathway NN cord-293714-s6ezxi5r 169 2 analysis analysis NN cord-293714-s6ezxi5r 169 3 using use VBG cord-293714-s6ezxi5r 169 4 all all DT cord-293714-s6ezxi5r 169 5 15 15 CD cord-293714-s6ezxi5r 169 6 genes gene NNS cord-293714-s6ezxi5r 169 7 further further RB cord-293714-s6ezxi5r 169 8 confirmed confirm VBD cord-293714-s6ezxi5r 169 9 the the DT cord-293714-s6ezxi5r 169 10 importance importance NN cord-293714-s6ezxi5r 169 11 of of IN cord-293714-s6ezxi5r 169 12 the the DT cord-293714-s6ezxi5r 169 13 TGF TGF NNP cord-293714-s6ezxi5r 169 14 - - HYPH cord-293714-s6ezxi5r 169 15 b b NN cord-293714-s6ezxi5r 169 16 pathway pathway NN cord-293714-s6ezxi5r 169 17 in in IN cord-293714-s6ezxi5r 169 18 KS KS NNP cord-293714-s6ezxi5r 169 19 pathogenesis pathogenesis NN cord-293714-s6ezxi5r 169 20 . . . cord-293714-s6ezxi5r 170 1 Because because IN cord-293714-s6ezxi5r 170 2 similar similar JJ cord-293714-s6ezxi5r 170 3 data datum NNS cord-293714-s6ezxi5r 170 4 regarding regard VBG cord-293714-s6ezxi5r 170 5 susceptibility susceptibility NN cord-293714-s6ezxi5r 170 6 were be VBD cord-293714-s6ezxi5r 170 7 reported report VBN cord-293714-s6ezxi5r 170 8 by by IN cord-293714-s6ezxi5r 170 9 Kuo Kuo NNP cord-293714-s6ezxi5r 170 10 et et NNP cord-293714-s6ezxi5r 170 11 al al NNP cord-293714-s6ezxi5r 170 12 . . . cord-293714-s6ezxi5r 171 1 102 102 CD cord-293714-s6ezxi5r 172 1 it -PRON- PRP cord-293714-s6ezxi5r 172 2 was be VBD cord-293714-s6ezxi5r 172 3 concluded conclude VBN cord-293714-s6ezxi5r 172 4 that that IN cord-293714-s6ezxi5r 172 5 genetic genetic JJ cord-293714-s6ezxi5r 172 6 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 172 7 in in IN cord-293714-s6ezxi5r 172 8 TGFB TGFB NNP cord-293714-s6ezxi5r 172 9 signalling signal VBG cord-293714-s6ezxi5r 172 10 pathway pathway NN cord-293714-s6ezxi5r 172 11 are be VBP cord-293714-s6ezxi5r 172 12 strictly strictly RB cord-293714-s6ezxi5r 172 13 associated associate VBN cord-293714-s6ezxi5r 172 14 with with IN cord-293714-s6ezxi5r 172 15 the the DT cord-293714-s6ezxi5r 172 16 risk risk NN cord-293714-s6ezxi5r 172 17 of of IN cord-293714-s6ezxi5r 172 18 development development NN cord-293714-s6ezxi5r 172 19 of of IN cord-293714-s6ezxi5r 172 20 KS KS NNP cord-293714-s6ezxi5r 172 21 . . . cord-293714-s6ezxi5r 173 1 However however RB cord-293714-s6ezxi5r 173 2 , , , cord-293714-s6ezxi5r 173 3 more more RBR cord-293714-s6ezxi5r 173 4 reliable reliable JJ cord-293714-s6ezxi5r 173 5 results result NNS cord-293714-s6ezxi5r 173 6 have have VBP cord-293714-s6ezxi5r 173 7 been be VBN cord-293714-s6ezxi5r 173 8 obtained obtain VBN cord-293714-s6ezxi5r 173 9 using use VBG cord-293714-s6ezxi5r 173 10 genome genome NN cord-293714-s6ezxi5r 173 11 - - HYPH cord-293714-s6ezxi5r 173 12 wide wide JJ cord-293714-s6ezxi5r 173 13 association association NN cord-293714-s6ezxi5r 173 14 studies study NNS cord-293714-s6ezxi5r 173 15 ( ( -LRB- cord-293714-s6ezxi5r 173 16 GWAS GWAS NNP cord-293714-s6ezxi5r 173 17 ) ) -RRB- cord-293714-s6ezxi5r 173 18 because because IN cord-293714-s6ezxi5r 173 19 genome genome NN cord-293714-s6ezxi5r 173 20 scanning scanning NN cord-293714-s6ezxi5r 173 21 without without IN cord-293714-s6ezxi5r 173 22 a a DT cord-293714-s6ezxi5r 173 23 defined define VBN cord-293714-s6ezxi5r 173 24 hypothesis hypothesis NN cord-293714-s6ezxi5r 173 25 has have VBZ cord-293714-s6ezxi5r 173 26 the the DT cord-293714-s6ezxi5r 173 27 advantage advantage NN cord-293714-s6ezxi5r 173 28 of of IN cord-293714-s6ezxi5r 173 29 identifying identify VBG cord-293714-s6ezxi5r 173 30 disease disease NN cord-293714-s6ezxi5r 173 31 genes gene NNS cord-293714-s6ezxi5r 173 32 even even RB cord-293714-s6ezxi5r 173 33 if if IN cord-293714-s6ezxi5r 173 34 the the DT cord-293714-s6ezxi5r 173 35 functions function NNS cord-293714-s6ezxi5r 173 36 of of IN cord-293714-s6ezxi5r 173 37 these these DT cord-293714-s6ezxi5r 173 38 genes gene NNS cord-293714-s6ezxi5r 173 39 are be VBP cord-293714-s6ezxi5r 173 40 not not RB cord-293714-s6ezxi5r 173 41 associated associate VBN cord-293714-s6ezxi5r 173 42 with with IN cord-293714-s6ezxi5r 173 43 previous previous JJ cord-293714-s6ezxi5r 173 44 knowledge knowledge NN cord-293714-s6ezxi5r 173 45 about about IN cord-293714-s6ezxi5r 173 46 the the DT cord-293714-s6ezxi5r 173 47 disease disease NN cord-293714-s6ezxi5r 173 48 's 's POS cord-293714-s6ezxi5r 173 49 pathophysiology pathophysiology NN cord-293714-s6ezxi5r 173 50 . . . cord-293714-s6ezxi5r 174 1 Even even RB cord-293714-s6ezxi5r 174 2 in in IN cord-293714-s6ezxi5r 174 3 this this DT cord-293714-s6ezxi5r 174 4 case case NN cord-293714-s6ezxi5r 174 5 , , , cord-293714-s6ezxi5r 174 6 the the DT cord-293714-s6ezxi5r 174 7 most most RBS cord-293714-s6ezxi5r 174 8 important important JJ cord-293714-s6ezxi5r 174 9 results result NNS cord-293714-s6ezxi5r 174 10 were be VBD cord-293714-s6ezxi5r 174 11 those those DT cord-293714-s6ezxi5r 174 12 repeatedly repeatedly RB cord-293714-s6ezxi5r 174 13 reported report VBN cord-293714-s6ezxi5r 174 14 in in IN cord-293714-s6ezxi5r 174 15 different different JJ cord-293714-s6ezxi5r 174 16 populations population NNS cord-293714-s6ezxi5r 174 17 . . . cord-293714-s6ezxi5r 175 1 By by IN cord-293714-s6ezxi5r 175 2 linkage linkage NN cord-293714-s6ezxi5r 175 3 disequilibrium disequilibrium NN cord-293714-s6ezxi5r 175 4 mapping mapping NN cord-293714-s6ezxi5r 175 5 performed perform VBN cord-293714-s6ezxi5r 175 6 on on IN cord-293714-s6ezxi5r 175 7 the the DT cord-293714-s6ezxi5r 175 8 region region NN cord-293714-s6ezxi5r 175 9 of of IN cord-293714-s6ezxi5r 175 10 chromosome chromosome NN cord-293714-s6ezxi5r 175 11 19q13.2 19q13.2 CD cord-293714-s6ezxi5r 175 12 , , , cord-293714-s6ezxi5r 175 13 it -PRON- PRP cord-293714-s6ezxi5r 175 14 was be VBD cord-293714-s6ezxi5r 175 15 found find VBN cord-293714-s6ezxi5r 175 16 that that IN cord-293714-s6ezxi5r 175 17 an an DT cord-293714-s6ezxi5r 175 18 SNP SNP NNP cord-293714-s6ezxi5r 175 19 within within IN cord-293714-s6ezxi5r 175 20 the the DT cord-293714-s6ezxi5r 175 21 inositol inositol NN cord-293714-s6ezxi5r 175 22 1 1 CD cord-293714-s6ezxi5r 175 23 , , , cord-293714-s6ezxi5r 175 24 4 4 CD cord-293714-s6ezxi5r 175 25 , , , cord-293714-s6ezxi5r 175 26 5-trisphosphonate 5-trisphosphonate CD cord-293714-s6ezxi5r 175 27 3-kinase 3-kinase CD cord-293714-s6ezxi5r 175 28 C C NNP cord-293714-s6ezxi5r 175 29 ( ( -LRB- cord-293714-s6ezxi5r 175 30 ITPKC ITPKC NNP cord-293714-s6ezxi5r 175 31 ) ) -RRB- cord-293714-s6ezxi5r 175 32 gene gene NN cord-293714-s6ezxi5r 175 33 , , , cord-293714-s6ezxi5r 175 34 a a DT cord-293714-s6ezxi5r 175 35 gene gene NN cord-293714-s6ezxi5r 175 36 that that WDT cord-293714-s6ezxi5r 175 37 regulates regulate VBZ cord-293714-s6ezxi5r 175 38 the the DT cord-293714-s6ezxi5r 175 39 signal signal NN cord-293714-s6ezxi5r 175 40 transduction transduction NN cord-293714-s6ezxi5r 175 41 in in IN cord-293714-s6ezxi5r 175 42 T T NNP cord-293714-s6ezxi5r 175 43 lymphocytes lymphocyte NNS cord-293714-s6ezxi5r 175 44 and and CC cord-293714-s6ezxi5r 175 45 the the DT cord-293714-s6ezxi5r 175 46 degree degree NN cord-293714-s6ezxi5r 175 47 of of IN cord-293714-s6ezxi5r 175 48 inflammatory inflammatory JJ cord-293714-s6ezxi5r 175 49 response response NN cord-293714-s6ezxi5r 175 50 , , , cord-293714-s6ezxi5r 175 51 was be VBD cord-293714-s6ezxi5r 175 52 associated associate VBN cord-293714-s6ezxi5r 175 53 with with IN cord-293714-s6ezxi5r 175 54 increased increase VBN cord-293714-s6ezxi5r 175 55 susceptibility susceptibility NN cord-293714-s6ezxi5r 175 56 to to IN cord-293714-s6ezxi5r 175 57 KS KS NNP cord-293714-s6ezxi5r 175 58 and and CC cord-293714-s6ezxi5r 175 59 with with IN cord-293714-s6ezxi5r 175 60 the the DT cord-293714-s6ezxi5r 175 61 development development NN cord-293714-s6ezxi5r 175 62 of of IN cord-293714-s6ezxi5r 175 63 coronary coronary JJ cord-293714-s6ezxi5r 175 64 artery artery NN cord-293714-s6ezxi5r 175 65 in in IN cord-293714-s6ezxi5r 175 66 both both CC cord-293714-s6ezxi5r 175 67 a a DT cord-293714-s6ezxi5r 175 68 Japanese Japanese NNP cord-293714-s6ezxi5r 175 69 and and CC cord-293714-s6ezxi5r 175 70 a a DT cord-293714-s6ezxi5r 175 71 USA USA NNP cord-293714-s6ezxi5r 175 72 population population NN cord-293714-s6ezxi5r 175 73 . . . cord-293714-s6ezxi5r 176 1 111 111 CD cord-293714-s6ezxi5r 177 1 Further further JJ cord-293714-s6ezxi5r 177 2 data datum NNS cord-293714-s6ezxi5r 177 3 confirming confirm VBG cord-293714-s6ezxi5r 177 4 the the DT cord-293714-s6ezxi5r 177 5 relationships relationship NNS cord-293714-s6ezxi5r 177 6 between between IN cord-293714-s6ezxi5r 177 7 genetics genetic NNS cord-293714-s6ezxi5r 177 8 and and CC cord-293714-s6ezxi5r 177 9 KS KS NNP cord-293714-s6ezxi5r 177 10 were be VBD cord-293714-s6ezxi5r 177 11 collected collect VBN cord-293714-s6ezxi5r 177 12 by by IN cord-293714-s6ezxi5r 177 13 Burgner Burgner NNP cord-293714-s6ezxi5r 177 14 et et NNP cord-293714-s6ezxi5r 177 15 al al NNP cord-293714-s6ezxi5r 177 16 .. .. . cord-293714-s6ezxi5r 178 1 112 112 CD cord-293714-s6ezxi5r 179 1 These these DT cord-293714-s6ezxi5r 179 2 authors author NNS cord-293714-s6ezxi5r 179 3 conducted conduct VBD cord-293714-s6ezxi5r 179 4 a a DT cord-293714-s6ezxi5r 179 5 GWAS GWAS NNP cord-293714-s6ezxi5r 179 6 with with IN cord-293714-s6ezxi5r 179 7 Dutch dutch JJ cord-293714-s6ezxi5r 179 8 KS KS NNP cord-293714-s6ezxi5r 179 9 cases case NNS cord-293714-s6ezxi5r 179 10 and and CC cord-293714-s6ezxi5r 179 11 controls control NNS cord-293714-s6ezxi5r 179 12 and and CC cord-293714-s6ezxi5r 179 13 followed follow VBD cord-293714-s6ezxi5r 179 14 up up RP cord-293714-s6ezxi5r 179 15 associations association NNS cord-293714-s6ezxi5r 179 16 signals signal NNS cord-293714-s6ezxi5r 179 17 with with IN cord-293714-s6ezxi5r 179 18 a a DT cord-293714-s6ezxi5r 179 19 family family NN cord-293714-s6ezxi5r 179 20 - - HYPH cord-293714-s6ezxi5r 179 21 based base VBN cord-293714-s6ezxi5r 179 22 association association NN cord-293714-s6ezxi5r 179 23 study study NN cord-293714-s6ezxi5r 179 24 of of IN cord-293714-s6ezxi5r 179 25 KS KS NNP cord-293714-s6ezxi5r 179 26 families family NNS cord-293714-s6ezxi5r 179 27 from from IN cord-293714-s6ezxi5r 179 28 Australia Australia NNP cord-293714-s6ezxi5r 179 29 , , , cord-293714-s6ezxi5r 179 30 USA USA NNP cord-293714-s6ezxi5r 179 31 , , , cord-293714-s6ezxi5r 179 32 and and CC cord-293714-s6ezxi5r 179 33 UK UK NNP cord-293714-s6ezxi5r 179 34 . . . cord-293714-s6ezxi5r 180 1 They -PRON- PRP cord-293714-s6ezxi5r 180 2 reported report VBD cord-293714-s6ezxi5r 180 3 that that IN cord-293714-s6ezxi5r 180 4 SNPs snp NNS cord-293714-s6ezxi5r 180 5 in in IN cord-293714-s6ezxi5r 180 6 intron intron NNP cord-293714-s6ezxi5r 180 7 3 3 CD cord-293714-s6ezxi5r 180 8 of of IN cord-293714-s6ezxi5r 180 9 N n CD cord-293714-s6ezxi5r 180 10 - - HYPH cord-293714-s6ezxi5r 180 11 acetylated acetylate VBN cord-293714-s6ezxi5r 180 12 a a DT cord-293714-s6ezxi5r 180 13 - - HYPH cord-293714-s6ezxi5r 180 14 acidic acidic JJ cord-293714-s6ezxi5r 180 15 dipeptidase dipeptidase NN cord-293714-s6ezxi5r 180 16 - - HYPH cord-293714-s6ezxi5r 180 17 like like JJ cord-293714-s6ezxi5r 180 18 2 2 CD cord-293714-s6ezxi5r 180 19 ( ( -LRB- cord-293714-s6ezxi5r 180 20 NAALADL2 NAALADL2 NNP cord-293714-s6ezxi5r 180 21 ) ) -RRB- cord-293714-s6ezxi5r 180 22 , , , cord-293714-s6ezxi5r 180 23 a a DT cord-293714-s6ezxi5r 180 24 protein protein NN cord-293714-s6ezxi5r 180 25 possibly possibly RB cord-293714-s6ezxi5r 180 26 involved involve VBN cord-293714-s6ezxi5r 180 27 in in IN cord-293714-s6ezxi5r 180 28 immune immune JJ cord-293714-s6ezxi5r 180 29 homeostasis homeostasis NN cord-293714-s6ezxi5r 180 30 , , , cord-293714-s6ezxi5r 180 31 were be VBD cord-293714-s6ezxi5r 180 32 associated associate VBN cord-293714-s6ezxi5r 180 33 with with IN cord-293714-s6ezxi5r 180 34 KS KS NNP cord-293714-s6ezxi5r 180 35 ( ( -LRB- cord-293714-s6ezxi5r 180 36 p p NN cord-293714-s6ezxi5r 180 37 Z z NN cord-293714-s6ezxi5r 180 38 1.13 1.13 CD cord-293714-s6ezxi5r 180 39 Â â CD cord-293714-s6ezxi5r 180 40 10 10 CD cord-293714-s6ezxi5r 180 41 À6 à6 CD cord-293714-s6ezxi5r 180 42 ) ) -RRB- cord-293714-s6ezxi5r 180 43 and and CC cord-293714-s6ezxi5r 180 44 that that IN cord-293714-s6ezxi5r 180 45 mRNA mRNA NNP cord-293714-s6ezxi5r 180 46 expression expression NN cord-293714-s6ezxi5r 180 47 of of IN cord-293714-s6ezxi5r 180 48 the the DT cord-293714-s6ezxi5r 180 49 same same JJ cord-293714-s6ezxi5r 180 50 protein protein NN cord-293714-s6ezxi5r 180 51 in in IN cord-293714-s6ezxi5r 180 52 erythrocytes erythrocyte NNS cord-293714-s6ezxi5r 180 53 was be VBD cord-293714-s6ezxi5r 180 54 significantly significantly RB cord-293714-s6ezxi5r 180 55 lower low JJR cord-293714-s6ezxi5r 180 56 in in IN cord-293714-s6ezxi5r 180 57 the the DT cord-293714-s6ezxi5r 180 58 acute acute JJ cord-293714-s6ezxi5r 180 59 phase phase NN cord-293714-s6ezxi5r 180 60 of of IN cord-293714-s6ezxi5r 180 61 KS KS NNP cord-293714-s6ezxi5r 180 62 than than IN cord-293714-s6ezxi5r 180 63 in in IN cord-293714-s6ezxi5r 180 64 the the DT cord-293714-s6ezxi5r 180 65 convalescence convalescence NN cord-293714-s6ezxi5r 180 66 period period NN cord-293714-s6ezxi5r 180 67 . . . cord-293714-s6ezxi5r 181 1 107 107 CD cord-293714-s6ezxi5r 182 1 The the DT cord-293714-s6ezxi5r 182 2 presence presence NN cord-293714-s6ezxi5r 182 3 of of IN cord-293714-s6ezxi5r 182 4 a a DT cord-293714-s6ezxi5r 182 5 predisposing predisposing JJ cord-293714-s6ezxi5r 182 6 genetic genetic JJ cord-293714-s6ezxi5r 182 7 system system NN cord-293714-s6ezxi5r 182 8 favouring favour VBG cord-293714-s6ezxi5r 182 9 the the DT cord-293714-s6ezxi5r 182 10 development development NN cord-293714-s6ezxi5r 182 11 of of IN cord-293714-s6ezxi5r 182 12 KS KS NNP cord-293714-s6ezxi5r 182 13 and and CC cord-293714-s6ezxi5r 182 14 regulating regulate VBG cord-293714-s6ezxi5r 182 15 its -PRON- PRP$ cord-293714-s6ezxi5r 182 16 severity severity NN cord-293714-s6ezxi5r 182 17 was be VBD cord-293714-s6ezxi5r 182 18 confirmed confirm VBN cord-293714-s6ezxi5r 182 19 by by IN cord-293714-s6ezxi5r 182 20 the the DT cord-293714-s6ezxi5r 182 21 study study NN cord-293714-s6ezxi5r 182 22 of of IN cord-293714-s6ezxi5r 182 23 Kim Kim NNP cord-293714-s6ezxi5r 182 24 et et NNP cord-293714-s6ezxi5r 182 25 al al NNP cord-293714-s6ezxi5r 182 26 . . NNP cord-293714-s6ezxi5r 182 27 , , , cord-293714-s6ezxi5r 182 28 113 113 CD cord-293714-s6ezxi5r 182 29 _SP cord-293714-s6ezxi5r 182 30 Korean korean JJ cord-293714-s6ezxi5r 182 31 KS KS NNP cord-293714-s6ezxi5r 182 32 patients patient NNS cord-293714-s6ezxi5r 182 33 and and CC cord-293714-s6ezxi5r 182 34 600 600 CD cord-293714-s6ezxi5r 182 35 healthy healthy JJ cord-293714-s6ezxi5r 182 36 controls control NNS cord-293714-s6ezxi5r 182 37 , , , cord-293714-s6ezxi5r 182 38 and and CC cord-293714-s6ezxi5r 182 39 found find VBD cord-293714-s6ezxi5r 182 40 that that IN cord-293714-s6ezxi5r 182 41 18 18 CD cord-293714-s6ezxi5r 182 42 genomic genomic JJ cord-293714-s6ezxi5r 182 43 regions region NNS cord-293714-s6ezxi5r 182 44 with with IN cord-293714-s6ezxi5r 182 45 one one CD cord-293714-s6ezxi5r 182 46 or or CC cord-293714-s6ezxi5r 182 47 more more JJR cord-293714-s6ezxi5r 182 48 sequence sequence NN cord-293714-s6ezxi5r 182 49 variants variant NNS cord-293714-s6ezxi5r 182 50 were be VBD cord-293714-s6ezxi5r 182 51 associated associate VBN cord-293714-s6ezxi5r 182 52 with with IN cord-293714-s6ezxi5r 182 53 KS KS NNP cord-293714-s6ezxi5r 182 54 , , , cord-293714-s6ezxi5r 182 55 and and CC cord-293714-s6ezxi5r 182 56 26 26 CD cord-293714-s6ezxi5r 182 57 were be VBD cord-293714-s6ezxi5r 182 58 associated associate VBN cord-293714-s6ezxi5r 182 59 with with IN cord-293714-s6ezxi5r 182 60 coronary coronary JJ cord-293714-s6ezxi5r 182 61 artery artery NN cord-293714-s6ezxi5r 182 62 lesions lesion NNS cord-293714-s6ezxi5r 182 63 ( ( -LRB- cord-293714-s6ezxi5r 182 64 CALs CALs NNPS cord-293714-s6ezxi5r 182 65 ) ) -RRB- cord-293714-s6ezxi5r 182 66 ( ( -LRB- cord-293714-s6ezxi5r 182 67 p p NN cord-293714-s6ezxi5r 182 68 < < XX cord-293714-s6ezxi5r 182 69 1 1 CD cord-293714-s6ezxi5r 182 70 Â â CD cord-293714-s6ezxi5r 182 71 10 10 CD cord-293714-s6ezxi5r 182 72 À5 À5 NNP cord-293714-s6ezxi5r 182 73 ) ) -RRB- cord-293714-s6ezxi5r 182 74 . . . cord-293714-s6ezxi5r 183 1 An an DT cord-293714-s6ezxi5r 183 2 SNP SNP NNP cord-293714-s6ezxi5r 183 3 within within IN cord-293714-s6ezxi5r 183 4 the the DT cord-293714-s6ezxi5r 183 5 disabled disabled JJ cord-293714-s6ezxi5r 183 6 homologue homologue NN cord-293714-s6ezxi5r 183 7 1 1 CD cord-293714-s6ezxi5r 183 8 ( ( -LRB- cord-293714-s6ezxi5r 183 9 DAB1 DAB1 NNP cord-293714-s6ezxi5r 183 10 ) ) -RRB- cord-293714-s6ezxi5r 183 11 gene gene NN cord-293714-s6ezxi5r 183 12 locus locus NN cord-293714-s6ezxi5r 183 13 in in IN cord-293714-s6ezxi5r 183 14 chromosome chromosome NN cord-293714-s6ezxi5r 183 15 1 1 CD cord-293714-s6ezxi5r 183 16 ( ( -LRB- cord-293714-s6ezxi5r 183 17 rs527409 rs527409 NNP cord-293714-s6ezxi5r 183 18 ) ) -RRB- cord-293714-s6ezxi5r 183 19 was be VBD cord-293714-s6ezxi5r 183 20 replicated replicate VBN cord-293714-s6ezxi5r 183 21 in in IN cord-293714-s6ezxi5r 183 22 266 266 CD cord-293714-s6ezxi5r 183 23 children child NNS cord-293714-s6ezxi5r 183 24 with with IN cord-293714-s6ezxi5r 183 25 KS KS NNP cord-293714-s6ezxi5r 183 26 and and CC cord-293714-s6ezxi5r 183 27 600 600 CD cord-293714-s6ezxi5r 183 28 114 114 CD cord-293714-s6ezxi5r 184 1 The the DT cord-293714-s6ezxi5r 184 2 most most RBS cord-293714-s6ezxi5r 184 3 strongly strongly RB cord-293714-s6ezxi5r 184 4 associated associate VBN cord-293714-s6ezxi5r 184 5 SNPs snp NNS cord-293714-s6ezxi5r 184 6 detected detect VBD cord-293714-s6ezxi5r 184 7 in in IN cord-293714-s6ezxi5r 184 8 the the DT cord-293714-s6ezxi5r 184 9 joint joint JJ cord-293714-s6ezxi5r 184 10 analysis analysis NN cord-293714-s6ezxi5r 184 11 corresponded correspond VBD cord-293714-s6ezxi5r 184 12 to to IN cord-293714-s6ezxi5r 184 13 three three CD cord-293714-s6ezxi5r 184 14 novel novel JJ cord-293714-s6ezxi5r 184 15 loci locus NNS cord-293714-s6ezxi5r 184 16 . . . cord-293714-s6ezxi5r 185 1 Among among IN cord-293714-s6ezxi5r 185 2 KD KD NNP cord-293714-s6ezxi5r 185 3 - - HYPH cord-293714-s6ezxi5r 185 4 associated associate VBN cord-293714-s6ezxi5r 185 5 SNPs SNPs NNPS cord-293714-s6ezxi5r 185 6 , , , cord-293714-s6ezxi5r 185 7 three three CD cord-293714-s6ezxi5r 185 8 were be VBD cord-293714-s6ezxi5r 185 9 close close JJ cord-293714-s6ezxi5r 185 10 to to IN cord-293714-s6ezxi5r 185 11 the the DT cord-293714-s6ezxi5r 185 12 COPB2 copb2 NN cord-293714-s6ezxi5r 186 1 ( ( -LRB- cord-293714-s6ezxi5r 186 2 coatomer coatomer NNP cord-293714-s6ezxi5r 186 3 protein protein NN cord-293714-s6ezxi5r 186 4 complex complex JJ cord-293714-s6ezxi5r 186 5 beta-2 beta-2 NN cord-293714-s6ezxi5r 186 6 subunit subunit NN cord-293714-s6ezxi5r 186 7 ) ) -RRB- cord-293714-s6ezxi5r 186 8 gene gene NN cord-293714-s6ezxi5r 186 9 : : : cord-293714-s6ezxi5r 186 10 rs1873668 rs1873668 . cord-293714-s6ezxi5r 187 1 ( ( -LRB- cord-293714-s6ezxi5r 187 2 p p NN cord-293714-s6ezxi5r 187 3 Z z NN cord-293714-s6ezxi5r 187 4 9.52 9.52 CD cord-293714-s6ezxi5r 187 5 Â â CD cord-293714-s6ezxi5r 187 6 10 10 CD cord-293714-s6ezxi5r 187 7 À5 À5 NNP cord-293714-s6ezxi5r 187 8 ) ) -RRB- cord-293714-s6ezxi5r 187 9 , , , cord-293714-s6ezxi5r 187 10 rs4243399 rs4243399 NNP cord-293714-s6ezxi5r 187 11 ( ( -LRB- cord-293714-s6ezxi5r 187 12 p p NN cord-293714-s6ezxi5r 187 13 Z z NN cord-293714-s6ezxi5r 187 14 9.93 9.93 CD cord-293714-s6ezxi5r 187 15 Â â CD cord-293714-s6ezxi5r 187 16 10 10 CD cord-293714-s6ezxi5r 187 17 À5 À5 NNP cord-293714-s6ezxi5r 187 18 ) ) -RRB- cord-293714-s6ezxi5r 187 19 , , , cord-293714-s6ezxi5r 187 20 and and CC cord-293714-s6ezxi5r 187 21 rs16849083 rs16849083 NNP cord-293714-s6ezxi5r 187 22 ( ( -LRB- cord-293714-s6ezxi5r 187 23 p p NN cord-293714-s6ezxi5r 187 24 Z z NN cord-293714-s6ezxi5r 187 25 9.93 9.93 CD cord-293714-s6ezxi5r 187 26 Â â CD cord-293714-s6ezxi5r 187 27 10 10 CD cord-293714-s6ezxi5r 187 28 À5 À5 NNP cord-293714-s6ezxi5r 187 29 ) ) -RRB- cord-293714-s6ezxi5r 187 30 . . . cord-293714-s6ezxi5r 188 1 Moreover moreover RB cord-293714-s6ezxi5r 188 2 , , , cord-293714-s6ezxi5r 188 3 an an DT cord-293714-s6ezxi5r 188 4 SNP SNP NNP cord-293714-s6ezxi5r 188 5 in in IN cord-293714-s6ezxi5r 188 6 the the DT cord-293714-s6ezxi5r 188 7 intronic intronic JJ cord-293714-s6ezxi5r 188 8 region region NN cord-293714-s6ezxi5r 188 9 of of IN cord-293714-s6ezxi5r 188 10 the the DT cord-293714-s6ezxi5r 188 11 ERAP1 erap1 NN cord-293714-s6ezxi5r 189 1 ( ( -LRB- cord-293714-s6ezxi5r 189 2 endoplasmic endoplasmic NN cord-293714-s6ezxi5r 189 3 reticulum reticulum NN cord-293714-s6ezxi5r 189 4 amino amino NN cord-293714-s6ezxi5r 189 5 peptidase peptidase NN cord-293714-s6ezxi5r 189 6 1 1 CD cord-293714-s6ezxi5r 189 7 ) ) -RRB- cord-293714-s6ezxi5r 189 8 gene gene NN cord-293714-s6ezxi5r 189 9 ( ( -LRB- cord-293714-s6ezxi5r 189 10 rs149481 rs149481 NN cord-293714-s6ezxi5r 189 11 , , , cord-293714-s6ezxi5r 189 12 p p NN cord-293714-s6ezxi5r 189 13 Z z NN cord-293714-s6ezxi5r 189 14 4.61 4.61 CD cord-293714-s6ezxi5r 189 15 Â â CD cord-293714-s6ezxi5r 189 16 10 10 CD cord-293714-s6ezxi5r 189 17 À5 À5 NNP cord-293714-s6ezxi5r 189 18 ) ) -RRB- cord-293714-s6ezxi5r 189 19 and and CC cord-293714-s6ezxi5r 189 20 six six CD cord-293714-s6ezxi5r 189 21 SNPs snp NNS cord-293714-s6ezxi5r 189 22 ( ( -LRB- cord-293714-s6ezxi5r 189 23 rs17113284 rs17113284 NNP cord-293714-s6ezxi5r 189 24 , , , cord-293714-s6ezxi5r 189 25 rs8005468 rs8005468 NNP cord-293714-s6ezxi5r 189 26 , , , cord-293714-s6ezxi5r 189 27 rs10129255 rs10129255 NNP cord-293714-s6ezxi5r 189 28 , , , cord-293714-s6ezxi5r 189 29 rs2007467 rs2007467 NNP cord-293714-s6ezxi5r 189 30 , , , cord-293714-s6ezxi5r 189 31 rs10150241 rs10150241 NNP cord-293714-s6ezxi5r 189 32 , , , cord-293714-s6ezxi5r 189 33 and and CC cord-293714-s6ezxi5r 189 34 rs12590667 rs12590667 NNP cord-293714-s6ezxi5r 189 35 ) ) -RRB- cord-293714-s6ezxi5r 189 36 clustered cluster VBD cord-293714-s6ezxi5r 189 37 in in IN cord-293714-s6ezxi5r 189 38 an an DT cord-293714-s6ezxi5r 189 39 area area NN cord-293714-s6ezxi5r 189 40 containing contain VBG cord-293714-s6ezxi5r 189 41 immunoglobulin immunoglobulin JJ cord-293714-s6ezxi5r 189 42 heavy heavy JJ cord-293714-s6ezxi5r 189 43 chain chain NN cord-293714-s6ezxi5r 189 44 variable variable JJ cord-293714-s6ezxi5r 189 45 regions region NNS cord-293714-s6ezxi5r 189 46 genes gene NNS cord-293714-s6ezxi5r 189 47 , , , cord-293714-s6ezxi5r 189 48 with with IN cord-293714-s6ezxi5r 189 49 p p NN cord-293714-s6ezxi5r 189 50 - - HYPH cord-293714-s6ezxi5r 189 51 values value NNS cord-293714-s6ezxi5r 189 52 between between IN cord-293714-s6ezxi5r 189 53 2.08 2.08 CD cord-293714-s6ezxi5r 189 54 Â â CD cord-293714-s6ezxi5r 189 55 10 10 CD cord-293714-s6ezxi5r 189 56 À5 À5 NNP cord-293714-s6ezxi5r 189 57 and and CC cord-293714-s6ezxi5r 189 58 8.93 8.93 CD cord-293714-s6ezxi5r 189 59 Â â CD cord-293714-s6ezxi5r 189 60 10 10 CD cord-293714-s6ezxi5r 189 61 À6 à6 NN cord-293714-s6ezxi5r 189 62 , , , cord-293714-s6ezxi5r 189 63 were be VBD cord-293714-s6ezxi5r 189 64 also also RB cord-293714-s6ezxi5r 189 65 identified identify VBN cord-293714-s6ezxi5r 189 66 . . . cord-293714-s6ezxi5r 190 1 Because because IN cord-293714-s6ezxi5r 190 2 these these DT cord-293714-s6ezxi5r 190 3 KD KD NNP cord-293714-s6ezxi5r 190 4 candidates candidate NNS cord-293714-s6ezxi5r 190 5 have have VBP cord-293714-s6ezxi5r 190 6 been be VBN cord-293714-s6ezxi5r 190 7 implicated implicate VBN cord-293714-s6ezxi5r 190 8 in in IN cord-293714-s6ezxi5r 190 9 T T NNP cord-293714-s6ezxi5r 190 10 cell cell NN cord-293714-s6ezxi5r 190 11 receptor receptor NN cord-293714-s6ezxi5r 190 12 signalling signalling NN cord-293714-s6ezxi5r 190 13 , , , cord-293714-s6ezxi5r 190 14 regulation regulation NN cord-293714-s6ezxi5r 190 15 of of IN cord-293714-s6ezxi5r 190 16 proinflammatory proinflammatory JJ cord-293714-s6ezxi5r 190 17 cytokines cytokine NNS cord-293714-s6ezxi5r 190 18 , , , cord-293714-s6ezxi5r 190 19 as as RB cord-293714-s6ezxi5r 190 20 well well RB cord-293714-s6ezxi5r 190 21 as as IN cord-293714-s6ezxi5r 190 22 antibody antibody NN cord-293714-s6ezxi5r 190 23 - - HYPH cord-293714-s6ezxi5r 190 24 mediated mediate VBN cord-293714-s6ezxi5r 190 25 immune immune JJ cord-293714-s6ezxi5r 190 26 responses response NNS cord-293714-s6ezxi5r 190 27 , , , cord-293714-s6ezxi5r 190 28 these these DT cord-293714-s6ezxi5r 190 29 findings finding NNS cord-293714-s6ezxi5r 190 30 strongly strongly RB cord-293714-s6ezxi5r 190 31 supported support VBD cord-293714-s6ezxi5r 190 32 the the DT cord-293714-s6ezxi5r 190 33 relationships relationship NNS cord-293714-s6ezxi5r 190 34 among among IN cord-293714-s6ezxi5r 190 35 genetics genetic NNS cord-293714-s6ezxi5r 190 36 , , , cord-293714-s6ezxi5r 190 37 alterations alteration NNS cord-293714-s6ezxi5r 190 38 in in IN cord-293714-s6ezxi5r 190 39 immune immune JJ cord-293714-s6ezxi5r 190 40 response response NN cord-293714-s6ezxi5r 190 41 and and CC cord-293714-s6ezxi5r 190 42 development development NN cord-293714-s6ezxi5r 190 43 of of IN cord-293714-s6ezxi5r 190 44 KS KS NNP cord-293714-s6ezxi5r 190 45 . . . cord-293714-s6ezxi5r 191 1 Association Association NNP cord-293714-s6ezxi5r 191 2 of of IN cord-293714-s6ezxi5r 191 3 SNPs SNPs NNPS cord-293714-s6ezxi5r 191 4 within within IN cord-293714-s6ezxi5r 191 5 the the DT cord-293714-s6ezxi5r 191 6 FCGR FCGR NNP cord-293714-s6ezxi5r 191 7 gene gene NN cord-293714-s6ezxi5r 191 8 cluster cluster NN cord-293714-s6ezxi5r 191 9 on on IN cord-293714-s6ezxi5r 191 10 chromosome chromosome NN cord-293714-s6ezxi5r 191 11 1 1 CD cord-293714-s6ezxi5r 191 12 with with IN cord-293714-s6ezxi5r 191 13 KS KS NNP cord-293714-s6ezxi5r 191 14 was be VBD cord-293714-s6ezxi5r 191 15 identified identify VBN cord-293714-s6ezxi5r 191 16 by by IN cord-293714-s6ezxi5r 191 17 Khor Khor NNP cord-293714-s6ezxi5r 191 18 et et NNP cord-293714-s6ezxi5r 191 19 al al NNP cord-293714-s6ezxi5r 191 20 . . . cord-293714-s6ezxi5r 192 1 in in IN cord-293714-s6ezxi5r 192 2 European european JJ cord-293714-s6ezxi5r 192 3 and and CC cord-293714-s6ezxi5r 192 4 Asian asian JJ cord-293714-s6ezxi5r 192 5 populations population NNS cord-293714-s6ezxi5r 192 6 . . . cord-293714-s6ezxi5r 193 1 115 115 CD cord-293714-s6ezxi5r 194 1 In in IN cord-293714-s6ezxi5r 194 2 a a DT cord-293714-s6ezxi5r 194 3 large large JJ cord-293714-s6ezxi5r 194 4 study study NN cord-293714-s6ezxi5r 194 5 sample sample NN cord-293714-s6ezxi5r 194 6 ( ( -LRB- cord-293714-s6ezxi5r 194 7 2173 2173 CD cord-293714-s6ezxi5r 194 8 individuals individual NNS cord-293714-s6ezxi5r 194 9 with with IN cord-293714-s6ezxi5r 194 10 KS KS NNP cord-293714-s6ezxi5r 194 11 and and CC cord-293714-s6ezxi5r 194 12 9383 9383 CD cord-293714-s6ezxi5r 194 13 controls control NNS cord-293714-s6ezxi5r 194 14 ) ) -RRB- cord-293714-s6ezxi5r 194 15 including include VBG cord-293714-s6ezxi5r 194 16 European european JJ cord-293714-s6ezxi5r 194 17 and and CC cord-293714-s6ezxi5r 194 18 Asian asian JJ cord-293714-s6ezxi5r 194 19 populations population NNS cord-293714-s6ezxi5r 194 20 , , , cord-293714-s6ezxi5r 194 21 these these DT cord-293714-s6ezxi5r 194 22 authors author NNS cord-293714-s6ezxi5r 194 23 found find VBD cord-293714-s6ezxi5r 194 24 that that IN cord-293714-s6ezxi5r 194 25 two two CD cord-293714-s6ezxi5r 194 26 loci locus NNS cord-293714-s6ezxi5r 194 27 exceeded exceed VBD cord-293714-s6ezxi5r 194 28 the the DT cord-293714-s6ezxi5r 194 29 formal formal JJ cord-293714-s6ezxi5r 194 30 threshold threshold NN cord-293714-s6ezxi5r 194 31 for for IN cord-293714-s6ezxi5r 194 32 genome genome NN cord-293714-s6ezxi5r 194 33 - - HYPH cord-293714-s6ezxi5r 194 34 wide wide JJ cord-293714-s6ezxi5r 194 35 significance significance NN cord-293714-s6ezxi5r 194 36 . . . cord-293714-s6ezxi5r 195 1 The the DT cord-293714-s6ezxi5r 195 2 first first JJ cord-293714-s6ezxi5r 195 3 was be VBD cord-293714-s6ezxi5r 195 4 a a DT cord-293714-s6ezxi5r 195 5 functional functional JJ cord-293714-s6ezxi5r 195 6 polymorphism polymorphism NN cord-293714-s6ezxi5r 195 7 in in IN cord-293714-s6ezxi5r 195 8 the the DT cord-293714-s6ezxi5r 195 9 IgG IgG NNP cord-293714-s6ezxi5r 195 10 receptor receptor NN cord-293714-s6ezxi5r 195 11 gene gene NN cord-293714-s6ezxi5r 195 12 FCGR2A FCGR2A NNP cord-293714-s6ezxi5r 195 13 encoding encode VBG cord-293714-s6ezxi5r 195 14 an an DT cord-293714-s6ezxi5r 195 15 H131R H131R NNP cord-293714-s6ezxi5r 195 16 substitution substitution NN cord-293714-s6ezxi5r 195 17 ( ( -LRB- cord-293714-s6ezxi5r 195 18 rs1801274 rs1801274 NN cord-293714-s6ezxi5r 195 19 ; ; : cord-293714-s6ezxi5r 195 20 p p NN cord-293714-s6ezxi5r 195 21 Z z NN cord-293714-s6ezxi5r 195 22 7.35 7.35 CD cord-293714-s6ezxi5r 195 23 Â â CD cord-293714-s6ezxi5r 195 24 10 10 CD cord-293714-s6ezxi5r 195 25 À11 À11 NNPS cord-293714-s6ezxi5r 195 26 , , , cord-293714-s6ezxi5r 195 27 OR or CC cord-293714-s6ezxi5r 195 28 Z z NN cord-293714-s6ezxi5r 195 29 1.32 1.32 CD cord-293714-s6ezxi5r 195 30 ) ) -RRB- cord-293714-s6ezxi5r 195 31 , , , cord-293714-s6ezxi5r 195 32 with with IN cord-293714-s6ezxi5r 195 33 the the DT cord-293714-s6ezxi5r 195 34 A a DT cord-293714-s6ezxi5r 195 35 allele allele NN cord-293714-s6ezxi5r 195 36 ( ( -LRB- cord-293714-s6ezxi5r 195 37 coding code VBG cord-293714-s6ezxi5r 195 38 for for IN cord-293714-s6ezxi5r 195 39 histidine histidine NN cord-293714-s6ezxi5r 195 40 ) ) -RRB- cord-293714-s6ezxi5r 195 41 leading lead VBG cord-293714-s6ezxi5r 195 42 to to IN cord-293714-s6ezxi5r 195 43 a a DT cord-293714-s6ezxi5r 195 44 high high JJ cord-293714-s6ezxi5r 195 45 risk risk NN cord-293714-s6ezxi5r 195 46 of of IN cord-293714-s6ezxi5r 195 47 disease disease NN cord-293714-s6ezxi5r 195 48 . . . cord-293714-s6ezxi5r 196 1 The the DT cord-293714-s6ezxi5r 196 2 second second JJ cord-293714-s6ezxi5r 196 3 was be VBD cord-293714-s6ezxi5r 196 4 at at IN cord-293714-s6ezxi5r 196 5 19q13 19q13 CD cord-293714-s6ezxi5r 197 1 ( ( -LRB- cord-293714-s6ezxi5r 197 2 p p NN cord-293714-s6ezxi5r 197 3 Z z NN cord-293714-s6ezxi5r 197 4 2.51 2.51 CD cord-293714-s6ezxi5r 197 5 Â â CD cord-293714-s6ezxi5r 197 6 10 10 CD cord-293714-s6ezxi5r 197 7 À9 à9 CD cord-293714-s6ezxi5r 197 8 , , , cord-293714-s6ezxi5r 197 9 OR or CC cord-293714-s6ezxi5r 197 10 Z z NN cord-293714-s6ezxi5r 197 11 1.42 1.42 CD cord-293714-s6ezxi5r 197 12 for for IN cord-293714-s6ezxi5r 197 13 the the DT cord-293714-s6ezxi5r 197 14 rs2233152 rs2233152 . cord-293714-s6ezxi5r 197 15 SNP SNP NNP cord-293714-s6ezxi5r 197 16 near near IN cord-293714-s6ezxi5r 197 17 MIA MIA NNP cord-293714-s6ezxi5r 197 18 and and CC cord-293714-s6ezxi5r 197 19 RAB4B RAB4B NNP cord-293714-s6ezxi5r 197 20 ; ; : cord-293714-s6ezxi5r 197 21 p p NN cord-293714-s6ezxi5r 197 22 Z z NN cord-293714-s6ezxi5r 197 23 1.68 1.68 CD cord-293714-s6ezxi5r 197 24 Â â CD cord-293714-s6ezxi5r 197 25 10 10 CD cord-293714-s6ezxi5r 197 26 À12 À12 NNP cord-293714-s6ezxi5r 197 27 , , , cord-293714-s6ezxi5r 197 28 OR or CC cord-293714-s6ezxi5r 197 29 Z z NN cord-293714-s6ezxi5r 197 30 1.52 1.52 CD cord-293714-s6ezxi5r 197 31 for for IN cord-293714-s6ezxi5r 197 32 rs28493229 rs28493229 NNP cord-293714-s6ezxi5r 197 33 in in IN cord-293714-s6ezxi5r 197 34 ITPKC ITPKC NNP cord-293714-s6ezxi5r 197 35 ) ) -RRB- cord-293714-s6ezxi5r 197 36 , , , cord-293714-s6ezxi5r 197 37 thus thus RB cord-293714-s6ezxi5r 197 38 confirming confirm VBG cord-293714-s6ezxi5r 197 39 the the DT cord-293714-s6ezxi5r 197 40 data datum NNS cord-293714-s6ezxi5r 197 41 previously previously RB cord-293714-s6ezxi5r 197 42 with with IN cord-293714-s6ezxi5r 197 43 previous previous JJ cord-293714-s6ezxi5r 197 44 studies study NNS cord-293714-s6ezxi5r 197 45 . . . cord-293714-s6ezxi5r 198 1 79 79 CD cord-293714-s6ezxi5r 199 1 The the DT cord-293714-s6ezxi5r 199 2 involvement involvement NN cord-293714-s6ezxi5r 199 3 of of IN cord-293714-s6ezxi5r 199 4 the the DT cord-293714-s6ezxi5r 199 5 FCGR2A fcgr2a JJ cord-293714-s6ezxi5r 199 6 locus locus NN cord-293714-s6ezxi5r 199 7 may may MD cord-293714-s6ezxi5r 199 8 have have VB cord-293714-s6ezxi5r 199 9 implications implication NNS cord-293714-s6ezxi5r 199 10 for for IN cord-293714-s6ezxi5r 199 11 understanding understand VBG cord-293714-s6ezxi5r 199 12 immune immune JJ cord-293714-s6ezxi5r 199 13 activation activation NN cord-293714-s6ezxi5r 199 14 in in IN cord-293714-s6ezxi5r 199 15 KS KS NNP cord-293714-s6ezxi5r 199 16 pathogenesis pathogenesis NN cord-293714-s6ezxi5r 199 17 and and CC cord-293714-s6ezxi5r 199 18 the the DT cord-293714-s6ezxi5r 199 19 mechanism mechanism NN cord-293714-s6ezxi5r 199 20 of of IN cord-293714-s6ezxi5r 199 21 response response NN cord-293714-s6ezxi5r 199 22 to to IN cord-293714-s6ezxi5r 199 23 intravenous intravenous JJ cord-293714-s6ezxi5r 199 24 immunoglobulin immunoglobulin NN cord-293714-s6ezxi5r 199 25 , , , cord-293714-s6ezxi5r 199 26 the the DT cord-293714-s6ezxi5r 199 27 only only JJ cord-293714-s6ezxi5r 199 28 proven prove VBN cord-293714-s6ezxi5r 199 29 therapy therapy NN cord-293714-s6ezxi5r 199 30 for for IN cord-293714-s6ezxi5r 199 31 this this DT cord-293714-s6ezxi5r 199 32 disease disease NN cord-293714-s6ezxi5r 199 33 . . . cord-293714-s6ezxi5r 200 1 More more RBR cord-293714-s6ezxi5r 200 2 recently recently RB cord-293714-s6ezxi5r 200 3 , , , cord-293714-s6ezxi5r 200 4 Japanese japanese JJ cord-293714-s6ezxi5r 200 5 and and CC cord-293714-s6ezxi5r 200 6 Taiwanese taiwanese JJ cord-293714-s6ezxi5r 200 7 groups group NNS cord-293714-s6ezxi5r 200 8 independently independently RB cord-293714-s6ezxi5r 200 9 reported report VBD cord-293714-s6ezxi5r 200 10 a a DT cord-293714-s6ezxi5r 200 11 significant significant JJ cord-293714-s6ezxi5r 200 12 association association NN cord-293714-s6ezxi5r 200 13 between between IN cord-293714-s6ezxi5r 200 14 KS KS NNP cord-293714-s6ezxi5r 200 15 and and CC cord-293714-s6ezxi5r 200 16 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 200 17 in in IN cord-293714-s6ezxi5r 200 18 the the DT cord-293714-s6ezxi5r 200 19 intergenic intergenic JJ cord-293714-s6ezxi5r 200 20 region region NN cord-293714-s6ezxi5r 200 21 on on IN cord-293714-s6ezxi5r 200 22 chromosome chromosome NN cord-293714-s6ezxi5r 200 23 8p23-p22 8p23-p22 CD cord-293714-s6ezxi5r 200 24 between between IN cord-293714-s6ezxi5r 200 25 B b NN cord-293714-s6ezxi5r 200 26 lymphoid lymphoid NN cord-293714-s6ezxi5r 200 27 kinase kinase NN cord-293714-s6ezxi5r 200 28 ( ( -LRB- cord-293714-s6ezxi5r 200 29 BLK BLK NNP cord-293714-s6ezxi5r 200 30 ) ) -RRB- cord-293714-s6ezxi5r 200 31 , , , cord-293714-s6ezxi5r 200 32 a a DT cord-293714-s6ezxi5r 200 33 tyrosine tyrosine NN cord-293714-s6ezxi5r 200 34 kinase kinase NN cord-293714-s6ezxi5r 200 35 involved involve VBN cord-293714-s6ezxi5r 200 36 in in IN cord-293714-s6ezxi5r 200 37 B b NN cord-293714-s6ezxi5r 200 38 - - HYPH cord-293714-s6ezxi5r 200 39 cell cell NN cord-293714-s6ezxi5r 200 40 receptor receptor NN cord-293714-s6ezxi5r 200 41 signal signal NN cord-293714-s6ezxi5r 200 42 transduction transduction NN cord-293714-s6ezxi5r 200 43 and and CC cord-293714-s6ezxi5r 200 44 FAM167A FAM167A NNP cord-293714-s6ezxi5r 200 45 , , , cord-293714-s6ezxi5r 200 46 a a DT cord-293714-s6ezxi5r 200 47 functionally functionally RB cord-293714-s6ezxi5r 200 48 uncharacterized uncharacterized JJ cord-293714-s6ezxi5r 200 49 gene gene NN cord-293714-s6ezxi5r 200 50 . . . cord-293714-s6ezxi5r 201 1 116 116 CD cord-293714-s6ezxi5r 201 2 , , , cord-293714-s6ezxi5r 201 3 117 117 CD cord-293714-s6ezxi5r 201 4 Onouchi Onouchi NNP cord-293714-s6ezxi5r 201 5 et et NNP cord-293714-s6ezxi5r 201 6 al al NNP cord-293714-s6ezxi5r 201 7 . . . cord-293714-s6ezxi5r 202 1 undertook undertake VBD cord-293714-s6ezxi5r 202 2 a a DT cord-293714-s6ezxi5r 202 3 GWAS GWAS NNP cord-293714-s6ezxi5r 202 4 involving involve VBG cord-293714-s6ezxi5r 202 5 428 428 CD cord-293714-s6ezxi5r 202 6 Japanese japanese JJ cord-293714-s6ezxi5r 202 7 individuals individual NNS cord-293714-s6ezxi5r 202 8 with with IN cord-293714-s6ezxi5r 202 9 KS KS NNP cord-293714-s6ezxi5r 202 10 and and CC cord-293714-s6ezxi5r 203 1 3379 3379 CD cord-293714-s6ezxi5r 203 2 Japanese japanese JJ cord-293714-s6ezxi5r 203 3 controls control NNS cord-293714-s6ezxi5r 203 4 genotyped genotype VBN cord-293714-s6ezxi5r 203 5 at at IN cord-293714-s6ezxi5r 203 6 473,803 473,803 CD cord-293714-s6ezxi5r 203 7 SNPs snp NNS cord-293714-s6ezxi5r 203 8 . . . cord-293714-s6ezxi5r 204 1 116 116 CD cord-293714-s6ezxi5r 205 1 They -PRON- PRP cord-293714-s6ezxi5r 205 2 validated validate VBD cord-293714-s6ezxi5r 205 3 the the DT cord-293714-s6ezxi5r 205 4 results result NNS cord-293714-s6ezxi5r 205 5 in in IN cord-293714-s6ezxi5r 205 6 two two CD cord-293714-s6ezxi5r 205 7 independent independent JJ cord-293714-s6ezxi5r 205 8 replication replication NN cord-293714-s6ezxi5r 205 9 panels panel NNS cord-293714-s6ezxi5r 205 10 of of IN cord-293714-s6ezxi5r 205 11 754 754 CD cord-293714-s6ezxi5r 205 12 cases case NNS cord-293714-s6ezxi5r 205 13 and and CC cord-293714-s6ezxi5r 205 14 947 947 CD cord-293714-s6ezxi5r 205 15 controls control NNS cord-293714-s6ezxi5r 205 16 , , , cord-293714-s6ezxi5r 205 17 and and CC cord-293714-s6ezxi5r 205 18 observed observe VBD cord-293714-s6ezxi5r 205 19 significant significant JJ cord-293714-s6ezxi5r 205 20 associations association NNS cord-293714-s6ezxi5r 205 21 in in IN cord-293714-s6ezxi5r 205 22 the the DT cord-293714-s6ezxi5r 205 23 FAM167A FAM167A NNP cord-293714-s6ezxi5r 205 24 - - HYPH cord-293714-s6ezxi5r 205 25 BLK blk NN cord-293714-s6ezxi5r 205 26 region region NN cord-293714-s6ezxi5r 205 27 ( ( -LRB- cord-293714-s6ezxi5r 205 28 rs2254546 rs2254546 NN cord-293714-s6ezxi5r 205 29 , , , cord-293714-s6ezxi5r 205 30 p p NN cord-293714-s6ezxi5r 205 31 Z z NN cord-293714-s6ezxi5r 205 32 8.2 8.2 CD cord-293714-s6ezxi5r 205 33 Â â CD cord-293714-s6ezxi5r 205 34 10 10 CD cord-293714-s6ezxi5r 205 35 À21 À21 NNP cord-293714-s6ezxi5r 205 36 ) ) -RRB- cord-293714-s6ezxi5r 205 37 . . . cord-293714-s6ezxi5r 206 1 Similar similar JJ cord-293714-s6ezxi5r 206 2 results result NNS cord-293714-s6ezxi5r 206 3 were be VBD cord-293714-s6ezxi5r 206 4 obtained obtain VBN cord-293714-s6ezxi5r 206 5 by by IN cord-293714-s6ezxi5r 206 6 Lee Lee NNP cord-293714-s6ezxi5r 206 7 et et NNP cord-293714-s6ezxi5r 206 8 al al NNP cord-293714-s6ezxi5r 206 9 . . . cord-293714-s6ezxi5r 207 1 in in IN cord-293714-s6ezxi5r 207 2 622 622 CD cord-293714-s6ezxi5r 207 3 individuals individual NNS cord-293714-s6ezxi5r 207 4 with with IN cord-293714-s6ezxi5r 207 5 KS KS NNP cord-293714-s6ezxi5r 207 6 and and CC cord-293714-s6ezxi5r 207 7 1107 1107 CD cord-293714-s6ezxi5r 207 8 controls control NNS cord-293714-s6ezxi5r 207 9 in in IN cord-293714-s6ezxi5r 207 10 a a DT cord-293714-s6ezxi5r 207 11 Han Han NNP cord-293714-s6ezxi5r 207 12 Chinese chinese JJ cord-293714-s6ezxi5r 207 13 population population NN cord-293714-s6ezxi5r 207 14 residing reside VBG cord-293714-s6ezxi5r 207 15 in in IN cord-293714-s6ezxi5r 207 16 Taiwan Taiwan NNP cord-293714-s6ezxi5r 207 17 , , , cord-293714-s6ezxi5r 207 18 with with IN cord-293714-s6ezxi5r 207 19 replication replication NN cord-293714-s6ezxi5r 207 20 in in IN cord-293714-s6ezxi5r 207 21 an an DT cord-293714-s6ezxi5r 207 22 independent independent JJ cord-293714-s6ezxi5r 207 23 Han Han NNP cord-293714-s6ezxi5r 207 24 Chinese chinese JJ cord-293714-s6ezxi5r 207 25 sample sample NN cord-293714-s6ezxi5r 207 26 of of IN cord-293714-s6ezxi5r 207 27 261 261 CD cord-293714-s6ezxi5r 207 28 cases case NNS cord-293714-s6ezxi5r 207 29 and and CC cord-293714-s6ezxi5r 207 30 550 550 CD cord-293714-s6ezxi5r 207 31 controls control NNS cord-293714-s6ezxi5r 207 32 . . . cord-293714-s6ezxi5r 208 1 117 117 CD cord-293714-s6ezxi5r 209 1 They -PRON- PRP cord-293714-s6ezxi5r 209 2 found find VBD cord-293714-s6ezxi5r 209 3 that that IN cord-293714-s6ezxi5r 209 4 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 209 5 at at IN cord-293714-s6ezxi5r 209 6 BLK blk NN cord-293714-s6ezxi5r 209 7 gene gene NN cord-293714-s6ezxi5r 209 8 together together RB cord-293714-s6ezxi5r 209 9 with with IN cord-293714-s6ezxi5r 209 10 genetic genetic JJ cord-293714-s6ezxi5r 209 11 abnormalities abnormality NNS cord-293714-s6ezxi5r 209 12 at at IN cord-293714-s6ezxi5r 209 13 CD40 CD40 NNP cord-293714-s6ezxi5r 209 14 , , , cord-293714-s6ezxi5r 209 15 were be VBD cord-293714-s6ezxi5r 209 16 associated associate VBN cord-293714-s6ezxi5r 209 17 with with IN cord-293714-s6ezxi5r 209 18 KS KS NNP cord-293714-s6ezxi5r 209 19 at at IN cord-293714-s6ezxi5r 209 20 genomewide genomewide NNP cord-293714-s6ezxi5r 209 21 significance significance NN cord-293714-s6ezxi5r 210 1 ( ( -LRB- cord-293714-s6ezxi5r 210 2 p p NN cord-293714-s6ezxi5r 210 3 < < XX cord-293714-s6ezxi5r 210 4 5.5 5.5 CD cord-293714-s6ezxi5r 210 5 Â â CD cord-293714-s6ezxi5r 210 6 10 10 CD cord-293714-s6ezxi5r 210 7 À8 à8 CD cord-293714-s6ezxi5r 210 8 ) ) -RRB- cord-293714-s6ezxi5r 210 9 confirming confirm VBG cord-293714-s6ezxi5r 210 10 the the DT cord-293714-s6ezxi5r 210 11 role role NN cord-293714-s6ezxi5r 210 12 of of IN cord-293714-s6ezxi5r 210 13 immune immune JJ cord-293714-s6ezxi5r 210 14 activation activation NN cord-293714-s6ezxi5r 210 15 and and CC cord-293714-s6ezxi5r 210 16 inflammation inflammation NN cord-293714-s6ezxi5r 210 17 in in IN cord-293714-s6ezxi5r 210 18 the the DT cord-293714-s6ezxi5r 210 19 pathogenesis pathogenesis NN cord-293714-s6ezxi5r 210 20 of of IN cord-293714-s6ezxi5r 210 21 the the DT cord-293714-s6ezxi5r 210 22 syndrome syndrome NN cord-293714-s6ezxi5r 210 23 . . . cord-293714-s6ezxi5r 211 1 However however RB cord-293714-s6ezxi5r 211 2 , , , cord-293714-s6ezxi5r 211 3 despite despite IN cord-293714-s6ezxi5r 211 4 these these DT cord-293714-s6ezxi5r 211 5 findings finding NNS cord-293714-s6ezxi5r 211 6 , , , cord-293714-s6ezxi5r 211 7 the the DT cord-293714-s6ezxi5r 211 8 correlations correlation NNS cord-293714-s6ezxi5r 211 9 between between IN cord-293714-s6ezxi5r 211 10 genetic genetic JJ cord-293714-s6ezxi5r 211 11 markers marker NNS cord-293714-s6ezxi5r 211 12 the the DT cord-293714-s6ezxi5r 211 13 risk risk NN cord-293714-s6ezxi5r 211 14 of of IN cord-293714-s6ezxi5r 211 15 developing develop VBG cord-293714-s6ezxi5r 211 16 and and CC cord-293714-s6ezxi5r 211 17 severity severity NN cord-293714-s6ezxi5r 211 18 of of IN cord-293714-s6ezxi5r 211 19 KS KS NNP cord-293714-s6ezxi5r 211 20 are be VBP cord-293714-s6ezxi5r 211 21 far far RB cord-293714-s6ezxi5r 211 22 from from IN cord-293714-s6ezxi5r 211 23 clear clear JJ cord-293714-s6ezxi5r 211 24 . . . cord-293714-s6ezxi5r 212 1 At at IN cord-293714-s6ezxi5r 212 2 the the DT cord-293714-s6ezxi5r 212 3 moment moment NN cord-293714-s6ezxi5r 212 4 the the DT cord-293714-s6ezxi5r 212 5 most most RBS cord-293714-s6ezxi5r 212 6 convincing convincing JJ cord-293714-s6ezxi5r 212 7 evidences evidence NNS cord-293714-s6ezxi5r 212 8 of of IN cord-293714-s6ezxi5r 212 9 a a DT cord-293714-s6ezxi5r 212 10 strict strict JJ cord-293714-s6ezxi5r 212 11 correlation correlation NN cord-293714-s6ezxi5r 212 12 between between IN cord-293714-s6ezxi5r 212 13 genetic genetic JJ cord-293714-s6ezxi5r 212 14 abnormalities abnormality NNS cord-293714-s6ezxi5r 212 15 and and CC cord-293714-s6ezxi5r 212 16 KS KS NNP cord-293714-s6ezxi5r 212 17 regards regard VBZ cord-293714-s6ezxi5r 212 18 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 212 19 of of IN cord-293714-s6ezxi5r 212 20 ITPKC ITPKC NNP cord-293714-s6ezxi5r 212 21 , , , cord-293714-s6ezxi5r 212 22 FCGR FCGR NNP cord-293714-s6ezxi5r 212 23 , , , cord-293714-s6ezxi5r 212 24 CASP3 CASP3 NNP cord-293714-s6ezxi5r 212 25 and and CC cord-293714-s6ezxi5r 212 26 TGFB TGFB NNP cord-293714-s6ezxi5r 212 27 genes gene NNS cord-293714-s6ezxi5r 212 28 . . . cord-293714-s6ezxi5r 213 1 Although although IN cord-293714-s6ezxi5r 213 2 various various JJ cord-293714-s6ezxi5r 213 3 data datum NNS cord-293714-s6ezxi5r 213 4 suggest suggest VBP cord-293714-s6ezxi5r 213 5 that that IN cord-293714-s6ezxi5r 213 6 KS KS NNP cord-293714-s6ezxi5r 213 7 is be VBZ cord-293714-s6ezxi5r 213 8 an an DT cord-293714-s6ezxi5r 213 9 infectionrelated infectionrelated JJ cord-293714-s6ezxi5r 213 10 clinical clinical JJ cord-293714-s6ezxi5r 213 11 syndrome syndrome NN cord-293714-s6ezxi5r 213 12 that that WDT cord-293714-s6ezxi5r 213 13 can can MD cord-293714-s6ezxi5r 213 14 only only RB cord-293714-s6ezxi5r 213 15 develop develop VB cord-293714-s6ezxi5r 213 16 in in IN cord-293714-s6ezxi5r 213 17 children child NNS cord-293714-s6ezxi5r 213 18 with with IN cord-293714-s6ezxi5r 213 19 predisposing predispose VBG cord-293714-s6ezxi5r 213 20 genetic genetic JJ cord-293714-s6ezxi5r 213 21 backgrounds background NNS cord-293714-s6ezxi5r 213 22 , , , cord-293714-s6ezxi5r 213 23 our -PRON- PRP$ cord-293714-s6ezxi5r 213 24 knowledge knowledge NN cord-293714-s6ezxi5r 213 25 of of IN cord-293714-s6ezxi5r 213 26 the the DT cord-293714-s6ezxi5r 213 27 infectious infectious JJ cord-293714-s6ezxi5r 213 28 agent(s agent(s NNP cord-293714-s6ezxi5r 213 29 ) ) -RRB- cord-293714-s6ezxi5r 213 30 involved involve VBN cord-293714-s6ezxi5r 213 31 and and CC cord-293714-s6ezxi5r 213 32 the the DT cord-293714-s6ezxi5r 213 33 genetic genetic JJ cord-293714-s6ezxi5r 213 34 characteristics characteristic NNS cord-293714-s6ezxi5r 213 35 of of IN cord-293714-s6ezxi5r 213 36 susceptible susceptible JJ cord-293714-s6ezxi5r 213 37 children child NNS cord-293714-s6ezxi5r 213 38 is be VBZ cord-293714-s6ezxi5r 213 39 still still RB cord-293714-s6ezxi5r 213 40 unsatisfactory unsatisfactory JJ cord-293714-s6ezxi5r 213 41 . . . cord-293714-s6ezxi5r 214 1 Either either CC cord-293714-s6ezxi5r 214 2 viruses virus NNS cord-293714-s6ezxi5r 214 3 or or CC cord-293714-s6ezxi5r 214 4 bacteria bacteria NNS cord-293714-s6ezxi5r 214 5 could could MD cord-293714-s6ezxi5r 214 6 act act VB cord-293714-s6ezxi5r 214 7 as as IN cord-293714-s6ezxi5r 214 8 disease disease NN cord-293714-s6ezxi5r 214 9 , , , cord-293714-s6ezxi5r 214 10 but but CC cord-293714-s6ezxi5r 214 11 no no DT cord-293714-s6ezxi5r 214 12 specific specific JJ cord-293714-s6ezxi5r 214 13 infectious infectious JJ cord-293714-s6ezxi5r 214 14 agent agent NN cord-293714-s6ezxi5r 214 15 can can MD cord-293714-s6ezxi5r 214 16 be be VB cord-293714-s6ezxi5r 214 17 considered consider VBN cord-293714-s6ezxi5r 214 18 the the DT cord-293714-s6ezxi5r 214 19 definite definite JJ cord-293714-s6ezxi5r 214 20 cause cause NN cord-293714-s6ezxi5r 214 21 of of IN cord-293714-s6ezxi5r 214 22 KS KS NNP cord-293714-s6ezxi5r 214 23 , , , cord-293714-s6ezxi5r 214 24 and and CC cord-293714-s6ezxi5r 214 25 so so RB cord-293714-s6ezxi5r 214 26 no no DT cord-293714-s6ezxi5r 214 27 specific specific JJ cord-293714-s6ezxi5r 214 28 anti anti JJ cord-293714-s6ezxi5r 214 29 - - JJ cord-293714-s6ezxi5r 214 30 infective infective JJ cord-293714-s6ezxi5r 214 31 therapy therapy NN cord-293714-s6ezxi5r 214 32 can can MD cord-293714-s6ezxi5r 214 33 be be VB cord-293714-s6ezxi5r 214 34 developed develop VBN cord-293714-s6ezxi5r 214 35 . . . cord-293714-s6ezxi5r 215 1 Moreover moreover RB cord-293714-s6ezxi5r 215 2 , , , cord-293714-s6ezxi5r 215 3 although although IN cord-293714-s6ezxi5r 215 4 potential potential JJ cord-293714-s6ezxi5r 215 5 genetic genetic JJ cord-293714-s6ezxi5r 215 6 determinants determinant NNS cord-293714-s6ezxi5r 215 7 have have VBP cord-293714-s6ezxi5r 215 8 been be VBN cord-293714-s6ezxi5r 215 9 hypothesised hypothesise VBN cord-293714-s6ezxi5r 215 10 in in IN cord-293714-s6ezxi5r 215 11 subjects subject NNS cord-293714-s6ezxi5r 215 12 with with IN cord-293714-s6ezxi5r 215 13 KS KS NNP cord-293714-s6ezxi5r 215 14 , , , cord-293714-s6ezxi5r 215 15 none none NN cord-293714-s6ezxi5r 215 16 of of IN cord-293714-s6ezxi5r 215 17 them -PRON- PRP cord-293714-s6ezxi5r 215 18 can can MD cord-293714-s6ezxi5r 215 19 yet yet RB cord-293714-s6ezxi5r 215 20 be be VB cord-293714-s6ezxi5r 215 21 considered consider VBN cord-293714-s6ezxi5r 215 22 real real JJ cord-293714-s6ezxi5r 215 23 markers marker NNS cord-293714-s6ezxi5r 215 24 of of IN cord-293714-s6ezxi5r 215 25 disease disease NN cord-293714-s6ezxi5r 215 26 susceptibility susceptibility NN cord-293714-s6ezxi5r 215 27 . . . cord-293714-s6ezxi5r 216 1 Consequently consequently RB cord-293714-s6ezxi5r 216 2 , , , cord-293714-s6ezxi5r 216 3 the the DT cord-293714-s6ezxi5r 216 4 pathogenesis pathogenesis NN cord-293714-s6ezxi5r 216 5 of of IN cord-293714-s6ezxi5r 216 6 KS KS NNP cord-293714-s6ezxi5r 216 7 is be VBZ cord-293714-s6ezxi5r 216 8 only only RB cord-293714-s6ezxi5r 216 9 partially partially RB cord-293714-s6ezxi5r 216 10 known know VBN cord-293714-s6ezxi5r 216 11 and and CC cord-293714-s6ezxi5r 216 12 measures measure NNS cord-293714-s6ezxi5r 216 13 to to TO cord-293714-s6ezxi5r 216 14 prevent prevent VB cord-293714-s6ezxi5r 216 15 it -PRON- PRP cord-293714-s6ezxi5r 216 16 remain remain VBP cord-293714-s6ezxi5r 216 17 elusive elusive JJ cord-293714-s6ezxi5r 216 18 . . . cord-293714-s6ezxi5r 217 1 Further further JJ cord-293714-s6ezxi5r 217 2 studies study NNS cord-293714-s6ezxi5r 217 3 are be VBP cord-293714-s6ezxi5r 217 4 needed need VBN cord-293714-s6ezxi5r 217 5 to to TO cord-293714-s6ezxi5r 217 6 address address VB cord-293714-s6ezxi5r 217 7 the the DT cord-293714-s6ezxi5r 217 8 many many JJ cord-293714-s6ezxi5r 217 9 still still RB cord-293714-s6ezxi5r 217 10 open open JJ cord-293714-s6ezxi5r 217 11 questions question NNS cord-293714-s6ezxi5r 217 12 concerning concern VBG cord-293714-s6ezxi5r 217 13 this this DT cord-293714-s6ezxi5r 217 14 still still RB cord-293714-s6ezxi5r 217 15 enigmatic enigmatic JJ cord-293714-s6ezxi5r 217 16 disease disease NN cord-293714-s6ezxi5r 217 17 . . . cord-293714-s6ezxi5r 218 1 A a DT cord-293714-s6ezxi5r 218 2 new new JJ cord-293714-s6ezxi5r 218 3 infantile infantile JJ cord-293714-s6ezxi5r 218 4 acute acute JJ cord-293714-s6ezxi5r 218 5 febrile febrile JJ cord-293714-s6ezxi5r 218 6 mucocutaneous mucocutaneous JJ cord-293714-s6ezxi5r 218 7 lymph lymph NN cord-293714-s6ezxi5r 218 8 node node NN cord-293714-s6ezxi5r 218 9 syndrome syndrome NN cord-293714-s6ezxi5r 218 10 ( ( -LRB- cord-293714-s6ezxi5r 218 11 MLNS MLNS NNP cord-293714-s6ezxi5r 218 12 ) ) -RRB- cord-293714-s6ezxi5r 218 13 prevailing prevail VBG cord-293714-s6ezxi5r 218 14 in in IN cord-293714-s6ezxi5r 218 15 Japan Japan NNP cord-293714-s6ezxi5r 218 16 Current Current NNP cord-293714-s6ezxi5r 218 17 recommendations recommendation NNS cord-293714-s6ezxi5r 218 18 for for IN cord-293714-s6ezxi5r 218 19 the the DT cord-293714-s6ezxi5r 218 20 pharmacological pharmacological JJ cord-293714-s6ezxi5r 218 21 therapy therapy NN cord-293714-s6ezxi5r 218 22 in in IN cord-293714-s6ezxi5r 218 23 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 218 24 syndrome syndrome NN cord-293714-s6ezxi5r 218 25 and and CC cord-293714-s6ezxi5r 218 26 management management NN cord-293714-s6ezxi5r 218 27 of of IN cord-293714-s6ezxi5r 218 28 its -PRON- PRP$ cord-293714-s6ezxi5r 218 29 cardiovascular cardiovascular JJ cord-293714-s6ezxi5r 218 30 complications complication NNS cord-293714-s6ezxi5r 218 31 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 218 32 syndrome syndrome NN cord-293714-s6ezxi5r 218 33 : : : cord-293714-s6ezxi5r 218 34 an an DT cord-293714-s6ezxi5r 218 35 intriguing intriguing JJ cord-293714-s6ezxi5r 218 36 disease disease NN cord-293714-s6ezxi5r 218 37 with with IN cord-293714-s6ezxi5r 218 38 numerous numerous JJ cord-293714-s6ezxi5r 218 39 unsolved unsolved JJ cord-293714-s6ezxi5r 218 40 dilemmas dilemma NNS cord-293714-s6ezxi5r 218 41 Diagnosis diagnosis NN cord-293714-s6ezxi5r 218 42 , , , cord-293714-s6ezxi5r 218 43 treatment treatment NN cord-293714-s6ezxi5r 218 44 , , , cord-293714-s6ezxi5r 218 45 and and CC cord-293714-s6ezxi5r 218 46 long long JJ cord-293714-s6ezxi5r 218 47 - - HYPH cord-293714-s6ezxi5r 218 48 term term NN cord-293714-s6ezxi5r 218 49 management management NN cord-293714-s6ezxi5r 218 50 of of IN cord-293714-s6ezxi5r 218 51 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 218 52 disease disease NN cord-293714-s6ezxi5r 218 53 : : : cord-293714-s6ezxi5r 218 54 a a DT cord-293714-s6ezxi5r 218 55 statement statement NN cord-293714-s6ezxi5r 218 56 for for IN cord-293714-s6ezxi5r 218 57 health health NN cord-293714-s6ezxi5r 218 58 professionals professional NNS cord-293714-s6ezxi5r 218 59 from from IN cord-293714-s6ezxi5r 218 60 the the DT cord-293714-s6ezxi5r 218 61 Committee Committee NNP cord-293714-s6ezxi5r 218 62 on on IN cord-293714-s6ezxi5r 218 63 Rheumatic Rheumatic NNP cord-293714-s6ezxi5r 218 64 Fever Fever NNP cord-293714-s6ezxi5r 218 65 , , , cord-293714-s6ezxi5r 218 66 Endocarditis Endocarditis NNP cord-293714-s6ezxi5r 218 67 , , , cord-293714-s6ezxi5r 218 68 and and CC cord-293714-s6ezxi5r 218 69 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 218 70 Disease Disease NNP cord-293714-s6ezxi5r 218 71 , , , cord-293714-s6ezxi5r 218 72 Council Council NNP cord-293714-s6ezxi5r 218 73 on on IN cord-293714-s6ezxi5r 218 74 Cardiovascular Cardiovascular NNP cord-293714-s6ezxi5r 218 75 Disease Disease NNP cord-293714-s6ezxi5r 218 76 in in IN cord-293714-s6ezxi5r 218 77 the the DT cord-293714-s6ezxi5r 218 78 Young Young NNP cord-293714-s6ezxi5r 218 79 Discrimination Discrimination NNP cord-293714-s6ezxi5r 218 80 between between IN cord-293714-s6ezxi5r 218 81 incomplete incomplete JJ cord-293714-s6ezxi5r 218 82 and and CC cord-293714-s6ezxi5r 218 83 atypical atypical JJ cord-293714-s6ezxi5r 218 84 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 218 85 syndrome syndrome NN cord-293714-s6ezxi5r 218 86 versus versus IN cord-293714-s6ezxi5r 218 87 other other JJ cord-293714-s6ezxi5r 218 88 febrile febrile JJ cord-293714-s6ezxi5r 218 89 diseases disease NNS cord-293714-s6ezxi5r 218 90 in in IN cord-293714-s6ezxi5r 218 91 childhood childhood NN cord-293714-s6ezxi5r 218 92 : : : cord-293714-s6ezxi5r 218 93 results result NNS cord-293714-s6ezxi5r 218 94 from from IN cord-293714-s6ezxi5r 218 95 an an DT cord-293714-s6ezxi5r 218 96 international international JJ cord-293714-s6ezxi5r 218 97 registry registry NN cord-293714-s6ezxi5r 218 98 - - HYPH cord-293714-s6ezxi5r 218 99 based base VBN cord-293714-s6ezxi5r 218 100 study study NN cord-293714-s6ezxi5r 218 101 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 218 102 syndrome syndrome NN cord-293714-s6ezxi5r 218 103 - - HYPH cord-293714-s6ezxi5r 218 104 like like JJ cord-293714-s6ezxi5r 218 105 illness illness NN cord-293714-s6ezxi5r 218 106 associated associate VBN cord-293714-s6ezxi5r 218 107 with with IN cord-293714-s6ezxi5r 218 108 infection infection NN cord-293714-s6ezxi5r 218 109 caused cause VBN cord-293714-s6ezxi5r 218 110 by by IN cord-293714-s6ezxi5r 218 111 enterotoxin enterotoxin NNP cord-293714-s6ezxi5r 218 112 B B NNP cord-293714-s6ezxi5r 218 113 - - HYPH cord-293714-s6ezxi5r 218 114 secreting secrete VBG cord-293714-s6ezxi5r 218 115 Staphylococcus Staphylococcus NNP cord-293714-s6ezxi5r 218 116 aureus aureus NN cord-293714-s6ezxi5r 218 117 Development Development NNP cord-293714-s6ezxi5r 218 118 of of IN cord-293714-s6ezxi5r 218 119 serum serum NNP cord-293714-s6ezxi5r 218 120 IgM IgM NNP cord-293714-s6ezxi5r 218 121 antibodies antibody NNS cord-293714-s6ezxi5r 218 122 against against IN cord-293714-s6ezxi5r 218 123 superantigens superantigen NNS cord-293714-s6ezxi5r 218 124 of of IN cord-293714-s6ezxi5r 218 125 Staphylococcus Staphylococcus NNP cord-293714-s6ezxi5r 218 126 aureus aureus NN cord-293714-s6ezxi5r 218 127 and and CC cord-293714-s6ezxi5r 218 128 Streptococcus streptococcus NN cord-293714-s6ezxi5r 218 129 pyogenes pyogene NNS cord-293714-s6ezxi5r 218 130 in in IN cord-293714-s6ezxi5r 218 131 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 218 132 disease disease NN cord-293714-s6ezxi5r 218 133 Lack Lack NNP cord-293714-s6ezxi5r 218 134 of of IN cord-293714-s6ezxi5r 218 135 association association NN cord-293714-s6ezxi5r 218 136 between between IN cord-293714-s6ezxi5r 218 137 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 218 138 syndrome syndrome NN cord-293714-s6ezxi5r 218 139 and and CC cord-293714-s6ezxi5r 218 140 infection infection NN cord-293714-s6ezxi5r 218 141 with with IN cord-293714-s6ezxi5r 218 142 parvovirus parvovirus NN cord-293714-s6ezxi5r 218 143 B19 B19 NNP cord-293714-s6ezxi5r 218 144 , , , cord-293714-s6ezxi5r 218 145 human human JJ cord-293714-s6ezxi5r 218 146 herpesvirus herpesvirus NN cord-293714-s6ezxi5r 218 147 8 8 CD cord-293714-s6ezxi5r 218 148 , , , cord-293714-s6ezxi5r 218 149 TT TT NNP cord-293714-s6ezxi5r 218 150 virus virus NN cord-293714-s6ezxi5r 218 151 , , , cord-293714-s6ezxi5r 218 152 GB GB NNP cord-293714-s6ezxi5r 218 153 virus virus NN cord-293714-s6ezxi5r 218 154 C c NN cord-293714-s6ezxi5r 218 155 / / SYM cord-293714-s6ezxi5r 218 156 hepatitis hepatitis NN cord-293714-s6ezxi5r 218 157 G g NN cord-293714-s6ezxi5r 218 158 virus virus NN cord-293714-s6ezxi5r 218 159 or or CC cord-293714-s6ezxi5r 218 160 Chlamydia Chlamydia NNP cord-293714-s6ezxi5r 218 161 pneumoniae pneumoniae NN cord-293714-s6ezxi5r 219 1 Emerging emerge VBG cord-293714-s6ezxi5r 219 2 from from IN cord-293714-s6ezxi5r 219 3 obscurity obscurity NN cord-293714-s6ezxi5r 219 4 : : : cord-293714-s6ezxi5r 220 1 understanding understand VBG cord-293714-s6ezxi5r 220 2 pulmonary pulmonary JJ cord-293714-s6ezxi5r 220 3 and and CC cord-293714-s6ezxi5r 220 4 extrapulmonary extrapulmonary JJ cord-293714-s6ezxi5r 220 5 syndromes syndrome NNS cord-293714-s6ezxi5r 220 6 , , , cord-293714-s6ezxi5r 220 7 pathogenesis pathogenesis NN cord-293714-s6ezxi5r 220 8 and and CC cord-293714-s6ezxi5r 220 9 epidemiology epidemiology NN cord-293714-s6ezxi5r 220 10 of of IN cord-293714-s6ezxi5r 220 11 human human JJ cord-293714-s6ezxi5r 220 12 Mycoplasma Mycoplasma NNP cord-293714-s6ezxi5r 220 13 pneumonia pneumonia NN cord-293714-s6ezxi5r 220 14 infections infection NNS cord-293714-s6ezxi5r 220 15 Respiratory respiratory JJ cord-293714-s6ezxi5r 220 16 tract tract NN cord-293714-s6ezxi5r 220 17 infections infection NNS cord-293714-s6ezxi5r 220 18 by by IN cord-293714-s6ezxi5r 220 19 Mycoplasma mycoplasma NN cord-293714-s6ezxi5r 220 20 pneumoniae pneumoniae NNS cord-293714-s6ezxi5r 220 21 in in IN cord-293714-s6ezxi5r 220 22 children child NNS cord-293714-s6ezxi5r 220 23 : : : cord-293714-s6ezxi5r 220 24 a a DT cord-293714-s6ezxi5r 220 25 review review NN cord-293714-s6ezxi5r 220 26 of of IN cord-293714-s6ezxi5r 220 27 diagnostic diagnostic JJ cord-293714-s6ezxi5r 220 28 and and CC cord-293714-s6ezxi5r 220 29 therapeutic therapeutic JJ cord-293714-s6ezxi5r 220 30 measures measure NNS cord-293714-s6ezxi5r 220 31 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 220 32 disease disease NN cord-293714-s6ezxi5r 220 33 with with IN cord-293714-s6ezxi5r 220 34 a a DT cord-293714-s6ezxi5r 220 35 concomitant concomitant JJ cord-293714-s6ezxi5r 220 36 primary primary JJ cord-293714-s6ezxi5r 220 37 Epstein Epstein NNP cord-293714-s6ezxi5r 220 38 - - HYPH cord-293714-s6ezxi5r 220 39 Barr Barr NNP cord-293714-s6ezxi5r 220 40 virus virus NN cord-293714-s6ezxi5r 220 41 infection infection NN cord-293714-s6ezxi5r 220 42 Adenovirus Adenovirus NNP cord-293714-s6ezxi5r 220 43 type type NN cord-293714-s6ezxi5r 220 44 2 2 CD cord-293714-s6ezxi5r 220 45 isolated isolate VBN cord-293714-s6ezxi5r 220 46 from from IN cord-293714-s6ezxi5r 220 47 a a DT cord-293714-s6ezxi5r 220 48 patient patient NN cord-293714-s6ezxi5r 220 49 with with IN cord-293714-s6ezxi5r 220 50 fatal fatal JJ cord-293714-s6ezxi5r 220 51 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 220 52 disease disease NN cord-293714-s6ezxi5r 220 53 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 220 54 disease disease NN cord-293714-s6ezxi5r 220 55 and and CC cord-293714-s6ezxi5r 220 56 parvovirus parvovirus NN cord-293714-s6ezxi5r 220 57 B19 B19 NNP cord-293714-s6ezxi5r 220 58 infection infection NN cord-293714-s6ezxi5r 220 59 in in IN cord-293714-s6ezxi5r 220 60 an an DT cord-293714-s6ezxi5r 220 61 adult adult NN cord-293714-s6ezxi5r 220 62 HIV-1-infected hiv-1-infecte VBN cord-293714-s6ezxi5r 220 63 patient patient NN cord-293714-s6ezxi5r 220 64 Isolation isolation NN cord-293714-s6ezxi5r 220 65 of of IN cord-293714-s6ezxi5r 220 66 human human JJ cord-293714-s6ezxi5r 220 67 herpesvirus-6 herpesvirus-6 NNP cord-293714-s6ezxi5r 220 68 from from IN cord-293714-s6ezxi5r 220 69 an an DT cord-293714-s6ezxi5r 220 70 infant infant NN cord-293714-s6ezxi5r 220 71 with with IN cord-293714-s6ezxi5r 220 72 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 220 73 disease disease NN cord-293714-s6ezxi5r 220 74 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 220 75 disease disease NN cord-293714-s6ezxi5r 220 76 associated associate VBN cord-293714-s6ezxi5r 220 77 with with IN cord-293714-s6ezxi5r 220 78 Klebsiella Klebsiella NNP cord-293714-s6ezxi5r 220 79 pneumoniae pneumoniae NN cord-293714-s6ezxi5r 220 80 bacteremia bacteremia NN cord-293714-s6ezxi5r 220 81 and and CC cord-293714-s6ezxi5r 220 82 parainfluenza parainfluenza NNP cord-293714-s6ezxi5r 220 83 type type NNP cord-293714-s6ezxi5r 220 84 3 3 CD cord-293714-s6ezxi5r 220 85 virus virus NN cord-293714-s6ezxi5r 220 86 infection infection NN cord-293714-s6ezxi5r 220 87 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 220 88 disease disease NN cord-293714-s6ezxi5r 220 89 associated associate VBN cord-293714-s6ezxi5r 220 90 with with IN cord-293714-s6ezxi5r 220 91 measles measle NNS cord-293714-s6ezxi5r 220 92 virus virus NN cord-293714-s6ezxi5r 220 93 infection infection NN cord-293714-s6ezxi5r 220 94 in in IN cord-293714-s6ezxi5r 220 95 a a DT cord-293714-s6ezxi5r 220 96 monozygotic monozygotic NNP cord-293714-s6ezxi5r 220 97 twin twin NNP cord-293714-s6ezxi5r 220 98 Association Association NNP cord-293714-s6ezxi5r 220 99 of of IN cord-293714-s6ezxi5r 220 100 rotavirus rotavirus JJ cord-293714-s6ezxi5r 220 101 infection infection NN cord-293714-s6ezxi5r 220 102 with with IN cord-293714-s6ezxi5r 220 103 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 220 104 syndrome syndrome NN cord-293714-s6ezxi5r 220 105 Concomitant concomitant JJ cord-293714-s6ezxi5r 220 106 dengue dengue NN cord-293714-s6ezxi5r 220 107 hemorrhagic hemorrhagic JJ cord-293714-s6ezxi5r 220 108 fever fever NN cord-293714-s6ezxi5r 220 109 with with IN cord-293714-s6ezxi5r 220 110 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 220 111 disease disease NN cord-293714-s6ezxi5r 220 112 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 220 113 disease disease NN cord-293714-s6ezxi5r 220 114 associated associate VBN cord-293714-s6ezxi5r 220 115 with with IN cord-293714-s6ezxi5r 220 116 chickenpox chickenpox NN cord-293714-s6ezxi5r 220 117 : : : cord-293714-s6ezxi5r 220 118 report report VB cord-293714-s6ezxi5r 220 119 of of IN cord-293714-s6ezxi5r 220 120 two two CD cord-293714-s6ezxi5r 220 121 sibling sibling NN cord-293714-s6ezxi5r 220 122 cases case NNS cord-293714-s6ezxi5r 220 123 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 220 124 disease disease NN cord-293714-s6ezxi5r 220 125 coincident coincident JJ cord-293714-s6ezxi5r 220 126 with with IN cord-293714-s6ezxi5r 220 127 influenza influenza NN cord-293714-s6ezxi5r 220 128 A a DT cord-293714-s6ezxi5r 220 129 H1N1/09 h1n1/09 JJ cord-293714-s6ezxi5r 220 130 infection infection NN cord-293714-s6ezxi5r 220 131 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 220 132 syndrome syndrome NN cord-293714-s6ezxi5r 220 133 and and CC cord-293714-s6ezxi5r 220 134 concurrent concurrent JJ cord-293714-s6ezxi5r 220 135 Coxsackie Coxsackie NNP cord-293714-s6ezxi5r 220 136 - - HYPH cord-293714-s6ezxi5r 220 137 virus virus NN cord-293714-s6ezxi5r 220 138 B3 b3 NN cord-293714-s6ezxi5r 220 139 infection infection NN cord-293714-s6ezxi5r 220 140 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 220 141 disease disease NN cord-293714-s6ezxi5r 220 142 in in IN cord-293714-s6ezxi5r 220 143 England England NNP cord-293714-s6ezxi5r 220 144 : : : cord-293714-s6ezxi5r 220 145 ethnicity ethnicity NN cord-293714-s6ezxi5r 220 146 , , , cord-293714-s6ezxi5r 220 147 deprivation deprivation NN cord-293714-s6ezxi5r 220 148 , , , cord-293714-s6ezxi5r 220 149 and and CC cord-293714-s6ezxi5r 220 150 respiratory respiratory JJ cord-293714-s6ezxi5r 220 151 pathogens pathogen NNS cord-293714-s6ezxi5r 220 152 Association Association NNP cord-293714-s6ezxi5r 220 153 between between IN cord-293714-s6ezxi5r 220 154 a a DT cord-293714-s6ezxi5r 220 155 novel novel JJ cord-293714-s6ezxi5r 220 156 human human JJ cord-293714-s6ezxi5r 220 157 coronavirus coronavirus NN cord-293714-s6ezxi5r 220 158 and and CC cord-293714-s6ezxi5r 220 159 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 220 160 disease disease NN cord-293714-s6ezxi5r 220 161 Detection Detection NNP cord-293714-s6ezxi5r 220 162 of of IN cord-293714-s6ezxi5r 220 163 human human JJ cord-293714-s6ezxi5r 220 164 bocavirus bocavirus NN cord-293714-s6ezxi5r 220 165 in in IN cord-293714-s6ezxi5r 220 166 children child NNS cord-293714-s6ezxi5r 220 167 with with IN cord-293714-s6ezxi5r 220 168 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 220 169 disease disease NN cord-293714-s6ezxi5r 220 170 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 220 171 disease disease NN cord-293714-s6ezxi5r 220 172 and and CC cord-293714-s6ezxi5r 220 173 human human JJ cord-293714-s6ezxi5r 220 174 bocavirus bocavirus NNP cord-293714-s6ezxi5r 220 175 e e NNP cord-293714-s6ezxi5r 220 176 potential potential NNP cord-293714-s6ezxi5r 220 177 association association NNP cord-293714-s6ezxi5r 220 178 ? ? . cord-293714-s6ezxi5r 221 1 Human human JJ cord-293714-s6ezxi5r 221 2 coronavirus coronavirus NN cord-293714-s6ezxi5r 222 1 -NL63 -NL63 : cord-293714-s6ezxi5r 222 2 infection infection NN cord-293714-s6ezxi5r 222 3 is be VBZ cord-293714-s6ezxi5r 222 4 not not RB cord-293714-s6ezxi5r 222 5 associated associate VBN cord-293714-s6ezxi5r 222 6 with with IN cord-293714-s6ezxi5r 222 7 acute acute JJ cord-293714-s6ezxi5r 222 8 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 222 9 disease disease NN cord-293714-s6ezxi5r 222 10 Blinded blind VBN cord-293714-s6ezxi5r 222 11 case case NN cord-293714-s6ezxi5r 222 12 - - HYPH cord-293714-s6ezxi5r 222 13 control control NN cord-293714-s6ezxi5r 222 14 study study NN cord-293714-s6ezxi5r 222 15 of of IN cord-293714-s6ezxi5r 222 16 the the DT cord-293714-s6ezxi5r 222 17 relationship relationship NN cord-293714-s6ezxi5r 222 18 between between IN cord-293714-s6ezxi5r 222 19 human human JJ cord-293714-s6ezxi5r 222 20 coronavirus coronavirus NN cord-293714-s6ezxi5r 223 1 NL63 NL63 NNP cord-293714-s6ezxi5r 223 2 and and CC cord-293714-s6ezxi5r 223 3 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 223 4 syndrome syndrome NN cord-293714-s6ezxi5r 223 5 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 223 6 disease disease NN cord-293714-s6ezxi5r 223 7 lacks lack VBZ cord-293714-s6ezxi5r 223 8 association association NN cord-293714-s6ezxi5r 223 9 with with IN cord-293714-s6ezxi5r 223 10 human human JJ cord-293714-s6ezxi5r 223 11 coronavirus coronavirus NN cord-293714-s6ezxi5r 223 12 NL63 NL63 NNP cord-293714-s6ezxi5r 223 13 and and CC cord-293714-s6ezxi5r 223 14 human human JJ cord-293714-s6ezxi5r 223 15 bocavirus bocavirus NNP cord-293714-s6ezxi5r 223 16 Impact Impact NNP cord-293714-s6ezxi5r 223 17 of of IN cord-293714-s6ezxi5r 223 18 human human JJ cord-293714-s6ezxi5r 223 19 bocavirus bocavirus NN cord-293714-s6ezxi5r 223 20 on on IN cord-293714-s6ezxi5r 223 21 children child NNS cord-293714-s6ezxi5r 223 22 and and CC cord-293714-s6ezxi5r 223 23 their -PRON- PRP$ cord-293714-s6ezxi5r 223 24 families family NNS cord-293714-s6ezxi5r 223 25 Infections infection NNS cord-293714-s6ezxi5r 223 26 and and CC cord-293714-s6ezxi5r 223 27 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 223 28 disease disease NN cord-293714-s6ezxi5r 223 29 : : : cord-293714-s6ezxi5r 223 30 implications implication NNS cord-293714-s6ezxi5r 223 31 for for IN cord-293714-s6ezxi5r 223 32 coronary coronary JJ cord-293714-s6ezxi5r 223 33 artery artery NN cord-293714-s6ezxi5r 223 34 outcome outcome NN cord-293714-s6ezxi5r 223 35 Concomitant concomitant JJ cord-293714-s6ezxi5r 223 36 respiratory respiratory JJ cord-293714-s6ezxi5r 223 37 viral viral JJ cord-293714-s6ezxi5r 223 38 infections infection NNS cord-293714-s6ezxi5r 223 39 in in IN cord-293714-s6ezxi5r 223 40 children child NNS cord-293714-s6ezxi5r 223 41 with with IN cord-293714-s6ezxi5r 223 42 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 223 43 disease disease NN cord-293714-s6ezxi5r 223 44 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 223 45 disease disease NN cord-293714-s6ezxi5r 223 46 may may MD cord-293714-s6ezxi5r 223 47 be be VB cord-293714-s6ezxi5r 223 48 a a DT cord-293714-s6ezxi5r 223 49 hyperimmune hyperimmune JJ cord-293714-s6ezxi5r 223 50 reaction reaction NN cord-293714-s6ezxi5r 223 51 of of IN cord-293714-s6ezxi5r 223 52 genetically genetically RB cord-293714-s6ezxi5r 223 53 susceptible susceptible JJ cord-293714-s6ezxi5r 223 54 children child NNS cord-293714-s6ezxi5r 223 55 to to IN cord-293714-s6ezxi5r 223 56 variants variant NNS cord-293714-s6ezxi5r 223 57 of of IN cord-293714-s6ezxi5r 223 58 normal normal JJ cord-293714-s6ezxi5r 223 59 environmental environmental JJ cord-293714-s6ezxi5r 223 60 flora flora NNS cord-293714-s6ezxi5r 223 61 RNA rna NN cord-293714-s6ezxi5r 223 62 - - HYPH cord-293714-s6ezxi5r 223 63 containing contain VBG cord-293714-s6ezxi5r 223 64 cytoplasmic cytoplasmic JJ cord-293714-s6ezxi5r 223 65 inclusion inclusion NN cord-293714-s6ezxi5r 223 66 bodies body NNS cord-293714-s6ezxi5r 223 67 in in IN cord-293714-s6ezxi5r 223 68 ciliated ciliated JJ cord-293714-s6ezxi5r 223 69 bronchial bronchial JJ cord-293714-s6ezxi5r 223 70 epithelium epithelium NN cord-293714-s6ezxi5r 223 71 months month NNS cord-293714-s6ezxi5r 223 72 to to IN cord-293714-s6ezxi5r 223 73 years year NNS cord-293714-s6ezxi5r 223 74 after after IN cord-293714-s6ezxi5r 223 75 acute acute JJ cord-293714-s6ezxi5r 223 76 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 223 77 disease disease NN cord-293714-s6ezxi5r 223 78 Ultrastructural Ultrastructural NNP cord-293714-s6ezxi5r 223 79 , , , cord-293714-s6ezxi5r 223 80 immunofluorescence immunofluorescence NN cord-293714-s6ezxi5r 223 81 , , , cord-293714-s6ezxi5r 223 82 and and CC cord-293714-s6ezxi5r 223 83 RNA RNA NNP cord-293714-s6ezxi5r 223 84 evidence evidence NN cord-293714-s6ezxi5r 223 85 support support VBP cord-293714-s6ezxi5r 223 86 the the DT cord-293714-s6ezxi5r 223 87 hypothesis hypothesis NN cord-293714-s6ezxi5r 223 88 of of IN cord-293714-s6ezxi5r 223 89 a a DT cord-293714-s6ezxi5r 223 90 " " `` cord-293714-s6ezxi5r 223 91 new new JJ cord-293714-s6ezxi5r 223 92 " " '' cord-293714-s6ezxi5r 223 93 virus virus NN cord-293714-s6ezxi5r 223 94 associated associate VBN cord-293714-s6ezxi5r 223 95 with with IN cord-293714-s6ezxi5r 223 96 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 223 97 disease disease NN cord-293714-s6ezxi5r 223 98 Three three CD cord-293714-s6ezxi5r 223 99 linked link VBD cord-293714-s6ezxi5r 223 100 vasculopathic vasculopathic JJ cord-293714-s6ezxi5r 223 101 processes process NNS cord-293714-s6ezxi5r 223 102 characterize characterize VBP cord-293714-s6ezxi5r 223 103 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 223 104 disease disease NN cord-293714-s6ezxi5r 223 105 : : : cord-293714-s6ezxi5r 223 106 a a DT cord-293714-s6ezxi5r 223 107 light light NN cord-293714-s6ezxi5r 223 108 and and CC cord-293714-s6ezxi5r 223 109 transmission transmission NN cord-293714-s6ezxi5r 223 110 electron electron NN cord-293714-s6ezxi5r 223 111 microscopic microscopic JJ cord-293714-s6ezxi5r 223 112 study study NN cord-293714-s6ezxi5r 223 113 Epidemiology epidemiology NN cord-293714-s6ezxi5r 223 114 of of IN cord-293714-s6ezxi5r 223 115 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 223 116 disease disease NN cord-293714-s6ezxi5r 223 117 e e NNP cord-293714-s6ezxi5r 223 118 a a DT cord-293714-s6ezxi5r 223 119 30-year 30-year JJ cord-293714-s6ezxi5r 223 120 achievement achievement NN cord-293714-s6ezxi5r 223 121 . . . cord-293714-s6ezxi5r 224 1 Tokyo Tokyo NNP cord-293714-s6ezxi5r 224 2 : : : cord-293714-s6ezxi5r 224 3 Shindan Shindan NNP cord-293714-s6ezxi5r 224 4 - - HYPH cord-293714-s6ezxi5r 224 5 to to IN cord-293714-s6ezxi5r 224 6 - - HYPH cord-293714-s6ezxi5r 224 7 Chiryosha Chiryosha NNP cord-293714-s6ezxi5r 224 8 The the DT cord-293714-s6ezxi5r 224 9 male male JJ cord-293714-s6ezxi5r 224 10 predominance predominance NN cord-293714-s6ezxi5r 224 11 in in IN cord-293714-s6ezxi5r 224 12 the the DT cord-293714-s6ezxi5r 224 13 incidence incidence NN cord-293714-s6ezxi5r 224 14 of of IN cord-293714-s6ezxi5r 224 15 infectious infectious JJ cord-293714-s6ezxi5r 224 16 diseases disease NNS cord-293714-s6ezxi5r 224 17 in in IN cord-293714-s6ezxi5r 224 18 children child NNS cord-293714-s6ezxi5r 224 19 : : : cord-293714-s6ezxi5r 224 20 a a DT cord-293714-s6ezxi5r 224 21 postulated postulate VBN cord-293714-s6ezxi5r 224 22 explanation explanation NN cord-293714-s6ezxi5r 224 23 for for IN cord-293714-s6ezxi5r 224 24 disparities disparity NNS cord-293714-s6ezxi5r 224 25 in in IN cord-293714-s6ezxi5r 224 26 the the DT cord-293714-s6ezxi5r 224 27 literature literature NN cord-293714-s6ezxi5r 224 28 Genetic genetic JJ cord-293714-s6ezxi5r 224 29 susceptibility susceptibility NN cord-293714-s6ezxi5r 224 30 to to IN cord-293714-s6ezxi5r 224 31 infectious infectious JJ cord-293714-s6ezxi5r 224 32 diseases disease NNS cord-293714-s6ezxi5r 224 33 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 224 34 disease disease NN cord-293714-s6ezxi5r 224 35 : : : cord-293714-s6ezxi5r 224 36 a a DT cord-293714-s6ezxi5r 224 37 brief brief JJ cord-293714-s6ezxi5r 224 38 history history NN cord-293714-s6ezxi5r 224 39 Modelling model VBG cord-293714-s6ezxi5r 224 40 seasonal seasonal JJ cord-293714-s6ezxi5r 224 41 variations variation NNS cord-293714-s6ezxi5r 224 42 in in IN cord-293714-s6ezxi5r 224 43 the the DT cord-293714-s6ezxi5r 224 44 age age NN cord-293714-s6ezxi5r 224 45 and and CC cord-293714-s6ezxi5r 224 46 incidence incidence NN cord-293714-s6ezxi5r 224 47 of of IN cord-293714-s6ezxi5r 224 48 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 224 49 disease disease NN cord-293714-s6ezxi5r 224 50 to to TO cord-293714-s6ezxi5r 224 51 explore explore VB cord-293714-s6ezxi5r 224 52 possible possible JJ cord-293714-s6ezxi5r 224 53 infectious infectious JJ cord-293714-s6ezxi5r 224 54 aetiologies aetiology NNS cord-293714-s6ezxi5r 224 55 Relationship relationship NN cord-293714-s6ezxi5r 224 56 of of IN cord-293714-s6ezxi5r 224 57 climate climate NN cord-293714-s6ezxi5r 224 58 , , , cord-293714-s6ezxi5r 224 59 ethnicity ethnicity NN cord-293714-s6ezxi5r 224 60 and and CC cord-293714-s6ezxi5r 224 61 socioeconomic socioeconomic JJ cord-293714-s6ezxi5r 224 62 status status NN cord-293714-s6ezxi5r 224 63 to to IN cord-293714-s6ezxi5r 224 64 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 224 65 disease disease NN cord-293714-s6ezxi5r 224 66 in in IN cord-293714-s6ezxi5r 224 67 San San NNP cord-293714-s6ezxi5r 224 68 Diego Diego NNP cord-293714-s6ezxi5r 224 69 County County NNP cord-293714-s6ezxi5r 224 70 Association Association NNP cord-293714-s6ezxi5r 224 71 of of IN cord-293714-s6ezxi5r 224 72 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 224 73 disease disease NN cord-293714-s6ezxi5r 224 74 with with IN cord-293714-s6ezxi5r 224 75 tropospheric tropospheric JJ cord-293714-s6ezxi5r 224 76 wind wind NN cord-293714-s6ezxi5r 224 77 patterns pattern NNS cord-293714-s6ezxi5r 224 78 Infectious infectious JJ cord-293714-s6ezxi5r 224 79 disease disease NN cord-293714-s6ezxi5r 224 80 : : : cord-293714-s6ezxi5r 224 81 blowing blow VBG cord-293714-s6ezxi5r 224 82 in in IN cord-293714-s6ezxi5r 224 83 the the DT cord-293714-s6ezxi5r 224 84 wind wind NN cord-293714-s6ezxi5r 224 85 Cardiac Cardiac NNP cord-293714-s6ezxi5r 224 86 sequelae sequela NNS cord-293714-s6ezxi5r 224 87 of of IN cord-293714-s6ezxi5r 224 88 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 224 89 disease disease NN cord-293714-s6ezxi5r 224 90 among among IN cord-293714-s6ezxi5r 224 91 recurrent recurrent JJ cord-293714-s6ezxi5r 224 92 cases case NNS cord-293714-s6ezxi5r 225 1 Superantigen Superantigen NNP cord-293714-s6ezxi5r 225 2 : : : cord-293714-s6ezxi5r 225 3 structureefunction structureefunction NN cord-293714-s6ezxi5r 225 4 relationships relationship NNS cord-293714-s6ezxi5r 225 5 Superantigen Superantigen NNP cord-293714-s6ezxi5r 225 6 - - HYPH cord-293714-s6ezxi5r 225 7 induced induce VBN cord-293714-s6ezxi5r 225 8 regulatory regulatory JJ cord-293714-s6ezxi5r 225 9 T t NN cord-293714-s6ezxi5r 225 10 cells cell NNS cord-293714-s6ezxi5r 225 11 in in IN cord-293714-s6ezxi5r 225 12 vivo vivo NN cord-293714-s6ezxi5r 226 1 The the DT cord-293714-s6ezxi5r 226 2 role role NN cord-293714-s6ezxi5r 226 3 of of IN cord-293714-s6ezxi5r 226 4 superantigens superantigen NNS cord-293714-s6ezxi5r 226 5 of of IN cord-293714-s6ezxi5r 226 6 group group NN cord-293714-s6ezxi5r 226 7 A a DT cord-293714-s6ezxi5r 226 8 Streptococcus Streptococcus NNP cord-293714-s6ezxi5r 226 9 and and CC cord-293714-s6ezxi5r 226 10 Staphylococcus Staphylococcus NNP cord-293714-s6ezxi5r 226 11 aureus aureus NN cord-293714-s6ezxi5r 226 12 in in IN cord-293714-s6ezxi5r 226 13 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 226 14 disease disease NN cord-293714-s6ezxi5r 226 15 TCR TCR NNP cord-293714-s6ezxi5r 226 16 Vb Vb NNP cord-293714-s6ezxi5r 226 17 family family NN cord-293714-s6ezxi5r 226 18 repertoire repertoire NN cord-293714-s6ezxi5r 226 19 and and CC cord-293714-s6ezxi5r 226 20 T T NNP cord-293714-s6ezxi5r 226 21 cell cell NN cord-293714-s6ezxi5r 226 22 activation activation NN cord-293714-s6ezxi5r 226 23 markers marker NNS cord-293714-s6ezxi5r 226 24 in in IN cord-293714-s6ezxi5r 226 25 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 226 26 disease disease NN cord-293714-s6ezxi5r 226 27 Characterization characterization NN cord-293714-s6ezxi5r 226 28 of of IN cord-293714-s6ezxi5r 226 29 CD4þ CD4þ NNP cord-293714-s6ezxi5r 226 30 T T NNP cord-293714-s6ezxi5r 226 31 helper helper NN cord-293714-s6ezxi5r 226 32 cells cell NNS cord-293714-s6ezxi5r 226 33 in in IN cord-293714-s6ezxi5r 226 34 patients patient NNS cord-293714-s6ezxi5r 226 35 with with IN cord-293714-s6ezxi5r 226 36 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 226 37 disease disease NN cord-293714-s6ezxi5r 226 38 ( ( -LRB- cord-293714-s6ezxi5r 226 39 KD KD NNP cord-293714-s6ezxi5r 226 40 ) ) -RRB- cord-293714-s6ezxi5r 226 41 : : : cord-293714-s6ezxi5r 226 42 preferential preferential JJ cord-293714-s6ezxi5r 226 43 production production NN cord-293714-s6ezxi5r 226 44 of of IN cord-293714-s6ezxi5r 226 45 tumor tumor NN cord-293714-s6ezxi5r 226 46 necrosis necrosis NN cord-293714-s6ezxi5r 226 47 factoralpha factoralpha NNP cord-293714-s6ezxi5r 226 48 ( ( -LRB- cord-293714-s6ezxi5r 226 49 TNF TNF NNP cord-293714-s6ezxi5r 226 50 - - HYPH cord-293714-s6ezxi5r 226 51 a a LS cord-293714-s6ezxi5r 226 52 ) ) -RRB- cord-293714-s6ezxi5r 226 53 by by IN cord-293714-s6ezxi5r 226 54 Vb2 Vb2 NNP cord-293714-s6ezxi5r 226 55 _ _ NNP cord-293714-s6ezxi5r 227 1 or or CC cord-293714-s6ezxi5r 227 2 Vb8 vb8 NN cord-293714-s6ezxi5r 227 3 _ _ NN cord-293714-s6ezxi5r 227 4 CD4þ CD4þ NNP cord-293714-s6ezxi5r 227 5 T T NNP cord-293714-s6ezxi5r 227 6 helper helper NN cord-293714-s6ezxi5r 227 7 cells cell NNS cord-293714-s6ezxi5r 228 1 The the DT cord-293714-s6ezxi5r 228 2 absence absence NN cord-293714-s6ezxi5r 228 3 of of IN cord-293714-s6ezxi5r 228 4 evidence evidence NN cord-293714-s6ezxi5r 228 5 of of IN cord-293714-s6ezxi5r 228 6 staphylococcal staphylococcal JJ cord-293714-s6ezxi5r 228 7 toxin toxin NN cord-293714-s6ezxi5r 228 8 involvement involvement NN cord-293714-s6ezxi5r 228 9 in in IN cord-293714-s6ezxi5r 228 10 the the DT cord-293714-s6ezxi5r 228 11 pathogenesis pathogenesis NN cord-293714-s6ezxi5r 228 12 of of IN cord-293714-s6ezxi5r 228 13 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 14 disease disease NN cord-293714-s6ezxi5r 228 15 Serologic Serologic NNP cord-293714-s6ezxi5r 228 16 evidence evidence NN cord-293714-s6ezxi5r 228 17 that that IN cord-293714-s6ezxi5r 228 18 streptococcal streptococcal JJ cord-293714-s6ezxi5r 228 19 superantigens superantigen NNS cord-293714-s6ezxi5r 228 20 are be VBP cord-293714-s6ezxi5r 228 21 not not RB cord-293714-s6ezxi5r 228 22 involved involve VBN cord-293714-s6ezxi5r 228 23 in in IN cord-293714-s6ezxi5r 228 24 the the DT cord-293714-s6ezxi5r 228 25 pathogenesis pathogenesis NN cord-293714-s6ezxi5r 228 26 of of IN cord-293714-s6ezxi5r 228 27 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 28 disease disease NN cord-293714-s6ezxi5r 228 29 Prevalence prevalence NN cord-293714-s6ezxi5r 228 30 of of IN cord-293714-s6ezxi5r 228 31 superantigen superantigen NN cord-293714-s6ezxi5r 228 32 - - HYPH cord-293714-s6ezxi5r 228 33 secreting secrete VBG cord-293714-s6ezxi5r 228 34 bacteria bacteria NNS cord-293714-s6ezxi5r 228 35 in in IN cord-293714-s6ezxi5r 228 36 patients patient NNS cord-293714-s6ezxi5r 228 37 with with IN cord-293714-s6ezxi5r 228 38 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 39 disease disease NN cord-293714-s6ezxi5r 228 40 Association Association NNP cord-293714-s6ezxi5r 228 41 of of IN cord-293714-s6ezxi5r 228 42 psoriasis psoriasis NN cord-293714-s6ezxi5r 228 43 - - HYPH cord-293714-s6ezxi5r 228 44 like like JJ cord-293714-s6ezxi5r 228 45 eruption eruption NN cord-293714-s6ezxi5r 228 46 and and CC cord-293714-s6ezxi5r 228 47 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 48 disease disease NN cord-293714-s6ezxi5r 228 49 Analysis Analysis NNP cord-293714-s6ezxi5r 228 50 of of IN cord-293714-s6ezxi5r 228 51 T T NNP cord-293714-s6ezxi5r 228 52 - - HYPH cord-293714-s6ezxi5r 228 53 cell cell NN cord-293714-s6ezxi5r 228 54 receptor receptor NN cord-293714-s6ezxi5r 228 55 V v NN cord-293714-s6ezxi5r 228 56 - - HYPH cord-293714-s6ezxi5r 228 57 beta beta NN cord-293714-s6ezxi5r 228 58 2 2 CD cord-293714-s6ezxi5r 228 59 in in IN cord-293714-s6ezxi5r 228 60 peripheral peripheral JJ cord-293714-s6ezxi5r 228 61 blood blood NN cord-293714-s6ezxi5r 228 62 lymphocytes lymphocyte NNS cord-293714-s6ezxi5r 228 63 as as IN cord-293714-s6ezxi5r 228 64 a a DT cord-293714-s6ezxi5r 228 65 diagnostic diagnostic JJ cord-293714-s6ezxi5r 228 66 marker marker NN cord-293714-s6ezxi5r 228 67 for for IN cord-293714-s6ezxi5r 228 68 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 69 disease disease NN cord-293714-s6ezxi5r 228 70 Selective selective JJ cord-293714-s6ezxi5r 228 71 increase increase NN cord-293714-s6ezxi5r 228 72 of of IN cord-293714-s6ezxi5r 228 73 V v NN cord-293714-s6ezxi5r 228 74 beta beta NN cord-293714-s6ezxi5r 228 75 2 2 CD cord-293714-s6ezxi5r 228 76 þ þ NN cord-293714-s6ezxi5r 228 77 T t NN cord-293714-s6ezxi5r 228 78 cells cell NNS cord-293714-s6ezxi5r 228 79 in in IN cord-293714-s6ezxi5r 228 80 the the DT cord-293714-s6ezxi5r 228 81 small small JJ cord-293714-s6ezxi5r 228 82 intestinal intestinal JJ cord-293714-s6ezxi5r 228 83 mucosa mucosa NN cord-293714-s6ezxi5r 228 84 in in IN cord-293714-s6ezxi5r 228 85 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 86 disease disease NN cord-293714-s6ezxi5r 228 87 T T NNP cord-293714-s6ezxi5r 228 88 cell cell NN cord-293714-s6ezxi5r 228 89 activation activation NN cord-293714-s6ezxi5r 228 90 profiles profile NNS cord-293714-s6ezxi5r 228 91 in in IN cord-293714-s6ezxi5r 228 92 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 93 syndrome syndrome NN cord-293714-s6ezxi5r 228 94 Detection Detection NNP cord-293714-s6ezxi5r 228 95 of of IN cord-293714-s6ezxi5r 228 96 multiple multiple JJ cord-293714-s6ezxi5r 228 97 superantigen superantigen NN cord-293714-s6ezxi5r 228 98 genes gene NNS cord-293714-s6ezxi5r 228 99 in in IN cord-293714-s6ezxi5r 228 100 stools stool NNS cord-293714-s6ezxi5r 228 101 of of IN cord-293714-s6ezxi5r 228 102 patients patient NNS cord-293714-s6ezxi5r 228 103 with with IN cord-293714-s6ezxi5r 228 104 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 105 disease disease NN cord-293714-s6ezxi5r 228 106 Epidemiologic epidemiologic JJ cord-293714-s6ezxi5r 228 107 features feature NNS cord-293714-s6ezxi5r 228 108 of of IN cord-293714-s6ezxi5r 228 109 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 110 disease disease NN cord-293714-s6ezxi5r 228 111 in in IN cord-293714-s6ezxi5r 228 112 Japan Japan NNP cord-293714-s6ezxi5r 228 113 : : : cord-293714-s6ezxi5r 228 114 results result NNS cord-293714-s6ezxi5r 228 115 of of IN cord-293714-s6ezxi5r 228 116 the the DT cord-293714-s6ezxi5r 228 117 2009e2010 2009e2010 JJ cord-293714-s6ezxi5r 228 118 nationwide nationwide JJ cord-293714-s6ezxi5r 228 119 survey survey NN cord-293714-s6ezxi5r 228 120 Epidemiology Epidemiology NNP cord-293714-s6ezxi5r 228 121 of of IN cord-293714-s6ezxi5r 228 122 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 123 disease disease NN cord-293714-s6ezxi5r 228 124 in in IN cord-293714-s6ezxi5r 228 125 Asia Asia NNP cord-293714-s6ezxi5r 228 126 , , , cord-293714-s6ezxi5r 228 127 Europe Europe NNP cord-293714-s6ezxi5r 228 128 , , , cord-293714-s6ezxi5r 228 129 and and CC cord-293714-s6ezxi5r 228 130 the the DT cord-293714-s6ezxi5r 228 131 United United NNP cord-293714-s6ezxi5r 228 132 States States NNP cord-293714-s6ezxi5r 228 133 Rising rise VBG cord-293714-s6ezxi5r 228 134 incidence incidence NN cord-293714-s6ezxi5r 228 135 of of IN cord-293714-s6ezxi5r 228 136 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 137 disease disease NN cord-293714-s6ezxi5r 228 138 in in IN cord-293714-s6ezxi5r 228 139 England England NNP cord-293714-s6ezxi5r 228 140 : : : cord-293714-s6ezxi5r 228 141 analysis analysis NN cord-293714-s6ezxi5r 228 142 of of IN cord-293714-s6ezxi5r 228 143 hospital hospital NN cord-293714-s6ezxi5r 228 144 admission admission NN cord-293714-s6ezxi5r 228 145 data datum NNS cord-293714-s6ezxi5r 228 146 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 147 syndrome syndrome NN cord-293714-s6ezxi5r 228 148 hospitalizations hospitalization NNS cord-293714-s6ezxi5r 228 149 in in IN cord-293714-s6ezxi5r 228 150 Ireland Ireland NNP cord-293714-s6ezxi5r 228 151 Increased increase VBN cord-293714-s6ezxi5r 228 152 detection detection NN cord-293714-s6ezxi5r 228 153 rate rate NN cord-293714-s6ezxi5r 228 154 of of IN cord-293714-s6ezxi5r 228 155 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 156 disease disease NN cord-293714-s6ezxi5r 228 157 using use VBG cord-293714-s6ezxi5r 228 158 new new JJ cord-293714-s6ezxi5r 228 159 diagnostic diagnostic JJ cord-293714-s6ezxi5r 228 160 algorithm algorithm NN cord-293714-s6ezxi5r 228 161 , , , cord-293714-s6ezxi5r 228 162 including include VBG cord-293714-s6ezxi5r 228 163 early early JJ cord-293714-s6ezxi5r 228 164 use use NN cord-293714-s6ezxi5r 228 165 of of IN cord-293714-s6ezxi5r 228 166 echocardiography echocardiography NN cord-293714-s6ezxi5r 228 167 Incidence incidence NN cord-293714-s6ezxi5r 228 168 of of IN cord-293714-s6ezxi5r 228 169 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 170 disease disease NN cord-293714-s6ezxi5r 228 171 in in IN cord-293714-s6ezxi5r 228 172 northern northern JJ cord-293714-s6ezxi5r 228 173 European european JJ cord-293714-s6ezxi5r 228 174 countries country NNS cord-293714-s6ezxi5r 228 175 Hospitalizations Hospitalizations NNPS cord-293714-s6ezxi5r 228 176 for for IN cord-293714-s6ezxi5r 228 177 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 178 syndrome syndrome NN cord-293714-s6ezxi5r 228 179 among among IN cord-293714-s6ezxi5r 228 180 children child NNS cord-293714-s6ezxi5r 228 181 in in IN cord-293714-s6ezxi5r 228 182 the the DT cord-293714-s6ezxi5r 228 183 United United NNP cord-293714-s6ezxi5r 228 184 States States NNP cord-293714-s6ezxi5r 228 185 Racial Racial NNP cord-293714-s6ezxi5r 228 186 / / SYM cord-293714-s6ezxi5r 228 187 ethnic ethnic JJ cord-293714-s6ezxi5r 228 188 differences difference NNS cord-293714-s6ezxi5r 228 189 in in IN cord-293714-s6ezxi5r 228 190 the the DT cord-293714-s6ezxi5r 228 191 incidence incidence NN cord-293714-s6ezxi5r 228 192 of of IN cord-293714-s6ezxi5r 228 193 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 194 syndrome syndrome NN cord-293714-s6ezxi5r 228 195 among among IN cord-293714-s6ezxi5r 228 196 children child NNS cord-293714-s6ezxi5r 228 197 in in IN cord-293714-s6ezxi5r 228 198 Hawaii Hawaii NNP cord-293714-s6ezxi5r 228 199 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 200 disease disease NN cord-293714-s6ezxi5r 228 201 in in IN cord-293714-s6ezxi5r 228 202 families family NNS cord-293714-s6ezxi5r 228 203 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 228 204 disease disease NN cord-293714-s6ezxi5r 228 205 in in IN cord-293714-s6ezxi5r 228 206 parents parent NNS cord-293714-s6ezxi5r 228 207 and and CC cord-293714-s6ezxi5r 228 208 children child NNS cord-293714-s6ezxi5r 229 1 The the DT cord-293714-s6ezxi5r 229 2 value value NN cord-293714-s6ezxi5r 229 3 of of IN cord-293714-s6ezxi5r 229 4 isolated isolate VBN cord-293714-s6ezxi5r 229 5 populations population NNS cord-293714-s6ezxi5r 229 6 in in IN cord-293714-s6ezxi5r 229 7 genetic genetic JJ cord-293714-s6ezxi5r 229 8 studies study NNS cord-293714-s6ezxi5r 229 9 of of IN cord-293714-s6ezxi5r 229 10 allergic allergic JJ cord-293714-s6ezxi5r 229 11 disease disease NN cord-293714-s6ezxi5r 229 12 High high JJ cord-293714-s6ezxi5r 229 13 incidence incidence NN cord-293714-s6ezxi5r 229 14 of of IN cord-293714-s6ezxi5r 229 15 angiotensin angiotensin NN cord-293714-s6ezxi5r 229 16 I -PRON- PRP cord-293714-s6ezxi5r 229 17 converting convert VBG cord-293714-s6ezxi5r 229 18 enzyme enzyme NN cord-293714-s6ezxi5r 229 19 genotype genotype NN cord-293714-s6ezxi5r 229 20 II II NNP cord-293714-s6ezxi5r 229 21 in in IN cord-293714-s6ezxi5r 229 22 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 229 23 disease disease NN cord-293714-s6ezxi5r 229 24 patients patient NNS cord-293714-s6ezxi5r 229 25 with with IN cord-293714-s6ezxi5r 229 26 coronary coronary JJ cord-293714-s6ezxi5r 229 27 aneurysm aneurysm NN cord-293714-s6ezxi5r 229 28 Polymorphism polymorphism NN cord-293714-s6ezxi5r 229 29 of of IN cord-293714-s6ezxi5r 229 30 angiotensin-1converting angiotensin-1converte VBG cord-293714-s6ezxi5r 229 31 enzyme enzyme NN cord-293714-s6ezxi5r 229 32 gene gene NN cord-293714-s6ezxi5r 229 33 and and CC cord-293714-s6ezxi5r 229 34 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 229 35 disease disease NN cord-293714-s6ezxi5r 229 36 Insertion insertion NN cord-293714-s6ezxi5r 229 37 / / SYM cord-293714-s6ezxi5r 229 38 deletion deletion NN cord-293714-s6ezxi5r 229 39 polymorphism polymorphism NN cord-293714-s6ezxi5r 229 40 of of IN cord-293714-s6ezxi5r 229 41 angiotensin angiotensin NN cord-293714-s6ezxi5r 229 42 converting convert VBG cord-293714-s6ezxi5r 229 43 enzyme enzyme NN cord-293714-s6ezxi5r 229 44 gene gene NN cord-293714-s6ezxi5r 229 45 in in IN cord-293714-s6ezxi5r 229 46 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 229 47 disease disease NN cord-293714-s6ezxi5r 229 48 Possible possible JJ cord-293714-s6ezxi5r 229 49 synergic synergic JJ cord-293714-s6ezxi5r 229 50 effect effect NN cord-293714-s6ezxi5r 229 51 of of IN cord-293714-s6ezxi5r 229 52 angiotensin angiotensin NN cord-293714-s6ezxi5r 230 1 -I -i DT cord-293714-s6ezxi5r 230 2 converting convert VBG cord-293714-s6ezxi5r 230 3 enzyme enzyme NN cord-293714-s6ezxi5r 230 4 gene gene NN cord-293714-s6ezxi5r 230 5 insertion insertion NN cord-293714-s6ezxi5r 230 6 / / SYM cord-293714-s6ezxi5r 230 7 deletion deletion NN cord-293714-s6ezxi5r 230 8 polymorphism polymorphism NN cord-293714-s6ezxi5r 230 9 and and CC cord-293714-s6ezxi5r 230 10 angiotensin angiotensin NN cord-293714-s6ezxi5r 230 11 - - HYPH cord-293714-s6ezxi5r 230 12 II II NNP cord-293714-s6ezxi5r 230 13 type-1 type-1 NNP cord-293714-s6ezxi5r 230 14 receptor receptor NN cord-293714-s6ezxi5r 230 15 1166A 1166A NNP cord-293714-s6ezxi5r 230 16 / / SYM cord-293714-s6ezxi5r 230 17 C c NN cord-293714-s6ezxi5r 230 18 gene gene NN cord-293714-s6ezxi5r 230 19 polymorphism polymorphism NN cord-293714-s6ezxi5r 230 20 on on IN cord-293714-s6ezxi5r 230 21 ischemic ischemic JJ cord-293714-s6ezxi5r 230 22 heart heart NN cord-293714-s6ezxi5r 230 23 disease disease NN cord-293714-s6ezxi5r 230 24 in in IN cord-293714-s6ezxi5r 230 25 patients patient NNS cord-293714-s6ezxi5r 230 26 with with IN cord-293714-s6ezxi5r 230 27 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 230 28 disease disease NN cord-293714-s6ezxi5r 230 29 Common common JJ cord-293714-s6ezxi5r 230 30 variants variant NNS cord-293714-s6ezxi5r 230 31 in in IN cord-293714-s6ezxi5r 230 32 CASP3 CASP3 NNP cord-293714-s6ezxi5r 230 33 confer confer VB cord-293714-s6ezxi5r 230 34 susceptibility susceptibility NN cord-293714-s6ezxi5r 230 35 to to IN cord-293714-s6ezxi5r 230 36 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 230 37 disease disease NN cord-293714-s6ezxi5r 230 38 Genetic genetic JJ cord-293714-s6ezxi5r 230 39 variations variation NNS cord-293714-s6ezxi5r 230 40 in in IN cord-293714-s6ezxi5r 230 41 the the DT cord-293714-s6ezxi5r 230 42 receptor receptor NN cord-293714-s6ezxi5r 230 43 - - HYPH cord-293714-s6ezxi5r 230 44 ligand ligand NN cord-293714-s6ezxi5r 230 45 pair pair NN cord-293714-s6ezxi5r 230 46 CCR5 CCR5 NNP cord-293714-s6ezxi5r 230 47 and and CC cord-293714-s6ezxi5r 230 48 CCL3L1 CCL3L1 NNP cord-293714-s6ezxi5r 230 49 are be VBP cord-293714-s6ezxi5r 230 50 important important JJ cord-293714-s6ezxi5r 230 51 determinants determinant NNS cord-293714-s6ezxi5r 230 52 of of IN cord-293714-s6ezxi5r 230 53 susceptibility susceptibility NN cord-293714-s6ezxi5r 230 54 to to IN cord-293714-s6ezxi5r 230 55 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 230 56 disease disease NN cord-293714-s6ezxi5r 231 1 The the DT cord-293714-s6ezxi5r 231 2 CCR5 CCR5 NNP cord-293714-s6ezxi5r 231 3 ( ( -LRB- cord-293714-s6ezxi5r 231 4 -2135C -2135c CD cord-293714-s6ezxi5r 231 5 / / SYM cord-293714-s6ezxi5r 231 6 T t NN cord-293714-s6ezxi5r 231 7 ) ) -RRB- cord-293714-s6ezxi5r 231 8 polymorphism polymorphism NN cord-293714-s6ezxi5r 231 9 may may MD cord-293714-s6ezxi5r 231 10 be be VB cord-293714-s6ezxi5r 231 11 associated associate VBN cord-293714-s6ezxi5r 231 12 with with IN cord-293714-s6ezxi5r 231 13 the the DT cord-293714-s6ezxi5r 231 14 development development NN cord-293714-s6ezxi5r 231 15 of of IN cord-293714-s6ezxi5r 231 16 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 231 17 disease disease NN cord-293714-s6ezxi5r 231 18 in in IN cord-293714-s6ezxi5r 231 19 Korean korean JJ cord-293714-s6ezxi5r 231 20 Children Children NNP cord-293714-s6ezxi5r 231 21 Polymorphisms Polymorphisms NNPS cord-293714-s6ezxi5r 231 22 in in IN cord-293714-s6ezxi5r 231 23 chemokine chemokine NN cord-293714-s6ezxi5r 231 24 receptor receptor NN cord-293714-s6ezxi5r 231 25 genes gene NNS cord-293714-s6ezxi5r 231 26 and and CC cord-293714-s6ezxi5r 231 27 susceptibility susceptibility NN cord-293714-s6ezxi5r 231 28 to to IN cord-293714-s6ezxi5r 231 29 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 231 30 disease disease NN cord-293714-s6ezxi5r 231 31 Genetic genetic JJ cord-293714-s6ezxi5r 231 32 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 231 33 in in IN cord-293714-s6ezxi5r 231 34 the the DT cord-293714-s6ezxi5r 231 35 CD40 CD40 NNP cord-293714-s6ezxi5r 231 36 ligand ligand NN cord-293714-s6ezxi5r 231 37 gene gene NN cord-293714-s6ezxi5r 231 38 and and CC cord-293714-s6ezxi5r 231 39 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 231 40 disease disease NN cord-293714-s6ezxi5r 231 41 Inflammatory inflammatory JJ cord-293714-s6ezxi5r 231 42 gene gene NN cord-293714-s6ezxi5r 231 43 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 231 44 and and CC cord-293714-s6ezxi5r 231 45 susceptibility susceptibility NN cord-293714-s6ezxi5r 231 46 to to IN cord-293714-s6ezxi5r 231 47 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 231 48 disease disease NN cord-293714-s6ezxi5r 231 49 and and CC cord-293714-s6ezxi5r 231 50 its -PRON- PRP$ cord-293714-s6ezxi5r 231 51 arterial arterial JJ cord-293714-s6ezxi5r 231 52 sequelae sequela NNS cord-293714-s6ezxi5r 231 53 Polymorphism polymorphism NN cord-293714-s6ezxi5r 231 54 of of IN cord-293714-s6ezxi5r 231 55 Fc Fc NNP cord-293714-s6ezxi5r 231 56 gamma gamma NN cord-293714-s6ezxi5r 231 57 RIIa RIIa NNS cord-293714-s6ezxi5r 231 58 may may MD cord-293714-s6ezxi5r 231 59 affect affect VB cord-293714-s6ezxi5r 231 60 the the DT cord-293714-s6ezxi5r 231 61 efficacy efficacy NN cord-293714-s6ezxi5r 231 62 of of IN cord-293714-s6ezxi5r 231 63 gamma gamma NN cord-293714-s6ezxi5r 231 64 - - HYPH cord-293714-s6ezxi5r 231 65 globulin globulin NN cord-293714-s6ezxi5r 231 66 therapy therapy NN cord-293714-s6ezxi5r 231 67 in in IN cord-293714-s6ezxi5r 231 68 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 231 69 disease disease NN cord-293714-s6ezxi5r 232 1 The the DT cord-293714-s6ezxi5r 232 2 involvement involvement NN cord-293714-s6ezxi5r 232 3 of of IN cord-293714-s6ezxi5r 232 4 Fc Fc NNP cord-293714-s6ezxi5r 232 5 gamma gamma NN cord-293714-s6ezxi5r 232 6 receptor receptor NN cord-293714-s6ezxi5r 232 7 gene gene NN cord-293714-s6ezxi5r 232 8 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 232 9 in in IN cord-293714-s6ezxi5r 232 10 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 232 11 disease disease NN cord-293714-s6ezxi5r 232 12 Association Association NNP cord-293714-s6ezxi5r 232 13 of of IN cord-293714-s6ezxi5r 232 14 IL-1Ra IL-1Ra NNP cord-293714-s6ezxi5r 232 15 gene gene NN cord-293714-s6ezxi5r 232 16 polymorphism polymorphism NN cord-293714-s6ezxi5r 232 17 , , , cord-293714-s6ezxi5r 232 18 but but CC cord-293714-s6ezxi5r 232 19 no no DT cord-293714-s6ezxi5r 232 20 association association NN cord-293714-s6ezxi5r 232 21 of of IN cord-293714-s6ezxi5r 232 22 IL-1beta IL-1beta NNP cord-293714-s6ezxi5r 232 23 and and CC cord-293714-s6ezxi5r 232 24 IL-4 IL-4 NNP cord-293714-s6ezxi5r 232 25 gene gene NN cord-293714-s6ezxi5r 232 26 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 232 27 , , , cord-293714-s6ezxi5r 232 28 with with IN cord-293714-s6ezxi5r 232 29 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 232 30 disease disease NN cord-293714-s6ezxi5r 233 1 The the DT cord-293714-s6ezxi5r 233 2 -590 -590 NN cord-293714-s6ezxi5r 233 3 C C NNP cord-293714-s6ezxi5r 233 4 / / SYM cord-293714-s6ezxi5r 233 5 T T NNP cord-293714-s6ezxi5r 233 6 and and CC cord-293714-s6ezxi5r 233 7 8375 8375 CD cord-293714-s6ezxi5r 234 1 A a LS cord-293714-s6ezxi5r 234 2 / / SYM cord-293714-s6ezxi5r 234 3 G g NN cord-293714-s6ezxi5r 234 4 interleukin-4 interleukin-4 NN cord-293714-s6ezxi5r 234 5 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 234 6 are be VBP cord-293714-s6ezxi5r 234 7 not not RB cord-293714-s6ezxi5r 234 8 associated associate VBN cord-293714-s6ezxi5r 234 9 with with IN cord-293714-s6ezxi5r 234 10 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 234 11 disease disease NN cord-293714-s6ezxi5r 234 12 in in IN cord-293714-s6ezxi5r 234 13 Taiwanese taiwanese JJ cord-293714-s6ezxi5r 234 14 children child NNS cord-293714-s6ezxi5r 235 1 Interleukin interleukin NN cord-293714-s6ezxi5r 235 2 6 6 CD cord-293714-s6ezxi5r 235 3 gene gene NN cord-293714-s6ezxi5r 235 4 promoter promoter NN cord-293714-s6ezxi5r 235 5 polymorphism polymorphism NN cord-293714-s6ezxi5r 235 6 is be VBZ cord-293714-s6ezxi5r 235 7 not not RB cord-293714-s6ezxi5r 235 8 associated associate VBN cord-293714-s6ezxi5r 235 9 with with IN cord-293714-s6ezxi5r 235 10 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 235 11 disease disease NN cord-293714-s6ezxi5r 236 1 The the DT cord-293714-s6ezxi5r 236 2 IL-10 IL-10 NNP cord-293714-s6ezxi5r 236 3 ( ( -LRB- cord-293714-s6ezxi5r 236 4 -627 -627 NNP cord-293714-s6ezxi5r 236 5 A A NNP cord-293714-s6ezxi5r 236 6 / / SYM cord-293714-s6ezxi5r 236 7 C C NNP cord-293714-s6ezxi5r 236 8 ) ) -RRB- cord-293714-s6ezxi5r 236 9 promoter promoter NN cord-293714-s6ezxi5r 236 10 polymorphism polymorphism NN cord-293714-s6ezxi5r 236 11 may may MD cord-293714-s6ezxi5r 236 12 be be VB cord-293714-s6ezxi5r 236 13 associated associate VBN cord-293714-s6ezxi5r 236 14 with with IN cord-293714-s6ezxi5r 236 15 coronary coronary JJ cord-293714-s6ezxi5r 236 16 aneurysms aneurysm NNS cord-293714-s6ezxi5r 236 17 and and CC cord-293714-s6ezxi5r 236 18 low low JJ cord-293714-s6ezxi5r 236 19 serum serum NN cord-293714-s6ezxi5r 236 20 albumin albumin NN cord-293714-s6ezxi5r 236 21 in in IN cord-293714-s6ezxi5r 236 22 Korean korean JJ cord-293714-s6ezxi5r 236 23 children child NNS cord-293714-s6ezxi5r 236 24 with with IN cord-293714-s6ezxi5r 236 25 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 236 26 disease disease NN cord-293714-s6ezxi5r 236 27 Influence influence NN cord-293714-s6ezxi5r 236 28 of of IN cord-293714-s6ezxi5r 236 29 interleukin interleukin NN cord-293714-s6ezxi5r 236 30 18 18 CD cord-293714-s6ezxi5r 236 31 promoter promoter NN cord-293714-s6ezxi5r 236 32 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 236 33 in in IN cord-293714-s6ezxi5r 236 34 susceptibility susceptibility NN cord-293714-s6ezxi5r 236 35 to to IN cord-293714-s6ezxi5r 236 36 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 236 37 disease disease NN cord-293714-s6ezxi5r 236 38 in in IN cord-293714-s6ezxi5r 236 39 Taiwan Taiwan NNP cord-293714-s6ezxi5r 236 40 Inducible Inducible NNP cord-293714-s6ezxi5r 236 41 and and CC cord-293714-s6ezxi5r 236 42 endothelial endothelial JJ cord-293714-s6ezxi5r 236 43 constitutive constitutive JJ cord-293714-s6ezxi5r 236 44 nitric nitric NN cord-293714-s6ezxi5r 236 45 oxide oxide NN cord-293714-s6ezxi5r 236 46 synthase synthase NN cord-293714-s6ezxi5r 236 47 gene gene NN cord-293714-s6ezxi5r 236 48 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 236 49 in in IN cord-293714-s6ezxi5r 236 50 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 236 51 disease disease NN cord-293714-s6ezxi5r 236 52 Increased increase VBN cord-293714-s6ezxi5r 236 53 frequency frequency NN cord-293714-s6ezxi5r 236 54 of of IN cord-293714-s6ezxi5r 236 55 alleles allele NNS cord-293714-s6ezxi5r 236 56 associated associate VBN cord-293714-s6ezxi5r 236 57 with with IN cord-293714-s6ezxi5r 236 58 elevated elevated JJ cord-293714-s6ezxi5r 236 59 tumor tumor NN cord-293714-s6ezxi5r 236 60 necrosis necrosis NN cord-293714-s6ezxi5r 236 61 factor factor NN cord-293714-s6ezxi5r 236 62 - - HYPH cord-293714-s6ezxi5r 236 63 alpha alpha NN cord-293714-s6ezxi5r 236 64 levels level NNS cord-293714-s6ezxi5r 236 65 in in IN cord-293714-s6ezxi5r 236 66 children child NNS cord-293714-s6ezxi5r 236 67 with with IN cord-293714-s6ezxi5r 236 68 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 236 69 disease disease NN cord-293714-s6ezxi5r 236 70 Association Association NNP cord-293714-s6ezxi5r 236 71 of of IN cord-293714-s6ezxi5r 236 72 mannose mannose NN cord-293714-s6ezxi5r 236 73 - - HYPH cord-293714-s6ezxi5r 236 74 binding bind VBG cord-293714-s6ezxi5r 236 75 lectin lectin NN cord-293714-s6ezxi5r 236 76 genotype genotype NN cord-293714-s6ezxi5r 236 77 with with IN cord-293714-s6ezxi5r 236 78 cardiovascular cardiovascular JJ cord-293714-s6ezxi5r 236 79 abnormalities abnormality NNS cord-293714-s6ezxi5r 236 80 in in IN cord-293714-s6ezxi5r 236 81 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 236 82 disease disease NN cord-293714-s6ezxi5r 236 83 Polymorphisms Polymorphisms NNPS cord-293714-s6ezxi5r 236 84 in in IN cord-293714-s6ezxi5r 236 85 the the DT cord-293714-s6ezxi5r 236 86 mannose mannose NN cord-293714-s6ezxi5r 236 87 - - HYPH cord-293714-s6ezxi5r 236 88 binding bind VBG cord-293714-s6ezxi5r 236 89 lectin lectin NN cord-293714-s6ezxi5r 236 90 gene gene NN cord-293714-s6ezxi5r 236 91 as as IN cord-293714-s6ezxi5r 236 92 determinants determinant NNS cord-293714-s6ezxi5r 236 93 of of IN cord-293714-s6ezxi5r 236 94 age age NN cord-293714-s6ezxi5r 236 95 - - HYPH cord-293714-s6ezxi5r 236 96 defined define VBN cord-293714-s6ezxi5r 236 97 risk risk NN cord-293714-s6ezxi5r 236 98 of of IN cord-293714-s6ezxi5r 236 99 coronary coronary JJ cord-293714-s6ezxi5r 236 100 artery artery NN cord-293714-s6ezxi5r 236 101 lesions lesion NNS cord-293714-s6ezxi5r 236 102 in in IN cord-293714-s6ezxi5r 236 103 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 236 104 disease disease NN cord-293714-s6ezxi5r 236 105 Modulating modulate VBG cord-293714-s6ezxi5r 236 106 effects effect NNS cord-293714-s6ezxi5r 236 107 of of IN cord-293714-s6ezxi5r 236 108 mannose mannose NN cord-293714-s6ezxi5r 236 109 binding bind VBG cord-293714-s6ezxi5r 236 110 lectin lectin NN cord-293714-s6ezxi5r 236 111 genotype genotype NN cord-293714-s6ezxi5r 236 112 on on IN cord-293714-s6ezxi5r 236 113 arterial arterial JJ cord-293714-s6ezxi5r 236 114 stiffness stiffness NN cord-293714-s6ezxi5r 236 115 in in IN cord-293714-s6ezxi5r 236 116 children child NNS cord-293714-s6ezxi5r 236 117 after after IN cord-293714-s6ezxi5r 236 118 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 236 119 disease disease NN cord-293714-s6ezxi5r 236 120 Monocyte Monocyte NNP cord-293714-s6ezxi5r 236 121 chemoattractant chemoattractant NN cord-293714-s6ezxi5r 236 122 protein protein NN cord-293714-s6ezxi5r 236 123 1 1 CD cord-293714-s6ezxi5r 236 124 gene gene NN cord-293714-s6ezxi5r 236 125 regulatory regulatory JJ cord-293714-s6ezxi5r 236 126 region region NN cord-293714-s6ezxi5r 236 127 polymorphism polymorphism NN cord-293714-s6ezxi5r 236 128 and and CC cord-293714-s6ezxi5r 236 129 serum serum NN cord-293714-s6ezxi5r 236 130 levels level NNS cord-293714-s6ezxi5r 236 131 of of IN cord-293714-s6ezxi5r 236 132 monocyte monocyte NNP cord-293714-s6ezxi5r 236 133 chemoattractant chemoattractant NNP cord-293714-s6ezxi5r 236 134 protein protein NN cord-293714-s6ezxi5r 236 135 1 1 CD cord-293714-s6ezxi5r 236 136 in in IN cord-293714-s6ezxi5r 236 137 Japanese japanese JJ cord-293714-s6ezxi5r 236 138 patients patient NNS cord-293714-s6ezxi5r 236 139 with with IN cord-293714-s6ezxi5r 236 140 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 236 141 disease disease NN cord-293714-s6ezxi5r 236 142 Polymorphism polymorphism NN cord-293714-s6ezxi5r 236 143 of of IN cord-293714-s6ezxi5r 236 144 transmembrane transmembrane NNP cord-293714-s6ezxi5r 236 145 region region NN cord-293714-s6ezxi5r 236 146 of of IN cord-293714-s6ezxi5r 236 147 MICA MICA NNP cord-293714-s6ezxi5r 236 148 gene gene NN cord-293714-s6ezxi5r 236 149 and and CC cord-293714-s6ezxi5r 236 150 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 236 151 disease disease NN cord-293714-s6ezxi5r 237 1 Circulating circulate VBG cord-293714-s6ezxi5r 237 2 matrix matrix NN cord-293714-s6ezxi5r 237 3 metalloproteinases metalloproteinase NNS cord-293714-s6ezxi5r 237 4 and and CC cord-293714-s6ezxi5r 237 5 their -PRON- PRP$ cord-293714-s6ezxi5r 237 6 inhibitors inhibitor NNS cord-293714-s6ezxi5r 237 7 in in IN cord-293714-s6ezxi5r 237 8 patients patient NNS cord-293714-s6ezxi5r 237 9 with with IN cord-293714-s6ezxi5r 237 10 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 237 11 disease disease NN cord-293714-s6ezxi5r 237 12 Polymorphism polymorphism NN cord-293714-s6ezxi5r 237 13 of of IN cord-293714-s6ezxi5r 237 14 matrix matrix NNP cord-293714-s6ezxi5r 237 15 metalloproteinase-3 metalloproteinase-3 NNP cord-293714-s6ezxi5r 237 16 promoter promoter NN cord-293714-s6ezxi5r 237 17 gene gene NN cord-293714-s6ezxi5r 237 18 as as IN cord-293714-s6ezxi5r 237 19 a a DT cord-293714-s6ezxi5r 237 20 risk risk NN cord-293714-s6ezxi5r 237 21 factor factor NN cord-293714-s6ezxi5r 237 22 for for IN cord-293714-s6ezxi5r 237 23 coronary coronary JJ cord-293714-s6ezxi5r 237 24 artery artery NN cord-293714-s6ezxi5r 237 25 lesions lesion NNS cord-293714-s6ezxi5r 237 26 in in IN cord-293714-s6ezxi5r 237 27 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 237 28 disease disease NN cord-293714-s6ezxi5r 237 29 Genetic genetic JJ cord-293714-s6ezxi5r 237 30 analysis analysis NN cord-293714-s6ezxi5r 237 31 of of IN cord-293714-s6ezxi5r 237 32 MMP MMP NNP cord-293714-s6ezxi5r 237 33 gene gene NN cord-293714-s6ezxi5r 237 34 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 237 35 in in IN cord-293714-s6ezxi5r 237 36 patients patient NNS cord-293714-s6ezxi5r 237 37 with with IN cord-293714-s6ezxi5r 237 38 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 237 39 disease disease NN cord-293714-s6ezxi5r 237 40 Association Association NNP cord-293714-s6ezxi5r 237 41 of of IN cord-293714-s6ezxi5r 237 42 the the DT cord-293714-s6ezxi5r 237 43 matrix matrix NN cord-293714-s6ezxi5r 237 44 metalloproteinase-3 metalloproteinase-3 NNP cord-293714-s6ezxi5r 238 1 ( ( -LRB- cord-293714-s6ezxi5r 238 2 -439C -439c NN cord-293714-s6ezxi5r 238 3 / / SYM cord-293714-s6ezxi5r 238 4 G g NN cord-293714-s6ezxi5r 238 5 ) ) -RRB- cord-293714-s6ezxi5r 238 6 promoter promoter NN cord-293714-s6ezxi5r 238 7 polymorphism polymorphism NN cord-293714-s6ezxi5r 238 8 with with IN cord-293714-s6ezxi5r 238 9 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 238 10 disease disease NN cord-293714-s6ezxi5r 238 11 in in IN cord-293714-s6ezxi5r 238 12 Korean korean JJ cord-293714-s6ezxi5r 238 13 children child NNS cord-293714-s6ezxi5r 238 14 Methylenetetrahydrofolate Methylenetetrahydrofolate NNP cord-293714-s6ezxi5r 238 15 reductase reductase NN cord-293714-s6ezxi5r 238 16 polymorphism polymorphism NN cord-293714-s6ezxi5r 238 17 in in IN cord-293714-s6ezxi5r 238 18 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 238 19 disease disease NN cord-293714-s6ezxi5r 239 1 A a DT cord-293714-s6ezxi5r 239 2 polymorphism polymorphism NN cord-293714-s6ezxi5r 239 3 in in IN cord-293714-s6ezxi5r 239 4 plasma plasma NN cord-293714-s6ezxi5r 239 5 platelet platelet NN cord-293714-s6ezxi5r 239 6 - - HYPH cord-293714-s6ezxi5r 239 7 activating activate VBG cord-293714-s6ezxi5r 239 8 factor factor NN cord-293714-s6ezxi5r 240 1 acetylhydrolase acetylhydrolase NNP cord-293714-s6ezxi5r 240 2 is be VBZ cord-293714-s6ezxi5r 240 3 involved involve VBN cord-293714-s6ezxi5r 240 4 in in IN cord-293714-s6ezxi5r 240 5 resistance resistance NN cord-293714-s6ezxi5r 240 6 to to IN cord-293714-s6ezxi5r 240 7 immunoglobulin immunoglobulin NN cord-293714-s6ezxi5r 240 8 treatment treatment NN cord-293714-s6ezxi5r 240 9 in in IN cord-293714-s6ezxi5r 240 10 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 240 11 disease disease NN cord-293714-s6ezxi5r 240 12 Polymorphism polymorphism NN cord-293714-s6ezxi5r 240 13 of of IN cord-293714-s6ezxi5r 240 14 SLC11A1 SLC11A1 NNP cord-293714-s6ezxi5r 241 1 ( ( -LRB- cord-293714-s6ezxi5r 241 2 formerly formerly RB cord-293714-s6ezxi5r 241 3 NRAMP1 nramp1 DT cord-293714-s6ezxi5r 241 4 ) ) -RRB- cord-293714-s6ezxi5r 242 1 gene gene NN cord-293714-s6ezxi5r 242 2 confers confer VBZ cord-293714-s6ezxi5r 242 3 susceptibility susceptibility NN cord-293714-s6ezxi5r 242 4 to to IN cord-293714-s6ezxi5r 242 5 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 242 6 disease disease NN cord-293714-s6ezxi5r 242 7 Transforming transform VBG cord-293714-s6ezxi5r 242 8 growth growth NN cord-293714-s6ezxi5r 242 9 factor factor NN cord-293714-s6ezxi5r 242 10 - - HYPH cord-293714-s6ezxi5r 242 11 beta beta NN cord-293714-s6ezxi5r 242 12 signaling signal VBG cord-293714-s6ezxi5r 242 13 pathway pathway NN cord-293714-s6ezxi5r 242 14 in in IN cord-293714-s6ezxi5r 242 15 patients patient NNS cord-293714-s6ezxi5r 242 16 with with IN cord-293714-s6ezxi5r 242 17 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 242 18 disease disease NN cord-293714-s6ezxi5r 242 19 Polymorphisms Polymorphisms NNP cord-293714-s6ezxi5r 242 20 of of IN cord-293714-s6ezxi5r 242 21 transforming transform VBG cord-293714-s6ezxi5r 242 22 growth growth NN cord-293714-s6ezxi5r 242 23 factor factor NN cord-293714-s6ezxi5r 242 24 - - HYPH cord-293714-s6ezxi5r 242 25 b b NN cord-293714-s6ezxi5r 242 26 signaling signal VBG cord-293714-s6ezxi5r 242 27 pathway pathway NN cord-293714-s6ezxi5r 242 28 and and CC cord-293714-s6ezxi5r 242 29 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 242 30 disease disease NN cord-293714-s6ezxi5r 242 31 in in IN cord-293714-s6ezxi5r 242 32 the the DT cord-293714-s6ezxi5r 242 33 Taiwanese taiwanese JJ cord-293714-s6ezxi5r 242 34 population population NN cord-293714-s6ezxi5r 242 35 Tissue tissue NN cord-293714-s6ezxi5r 242 36 inhibitor inhibitor NN cord-293714-s6ezxi5r 242 37 of of IN cord-293714-s6ezxi5r 242 38 metalloproteinase metalloproteinase NN cord-293714-s6ezxi5r 242 39 2 2 CD cord-293714-s6ezxi5r 242 40 and and CC cord-293714-s6ezxi5r 242 41 coronary coronary JJ cord-293714-s6ezxi5r 242 42 artery artery NN cord-293714-s6ezxi5r 242 43 lesions lesion NNS cord-293714-s6ezxi5r 242 44 in in IN cord-293714-s6ezxi5r 242 45 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 242 46 disease disease NN cord-293714-s6ezxi5r 242 47 Analysis Analysis NNP cord-293714-s6ezxi5r 242 48 of of IN cord-293714-s6ezxi5r 242 49 tumor tumor NN cord-293714-s6ezxi5r 242 50 necrosis necrosis NN cord-293714-s6ezxi5r 242 51 factor factor NN cord-293714-s6ezxi5r 242 52 - - HYPH cord-293714-s6ezxi5r 242 53 alpha alpha NN cord-293714-s6ezxi5r 242 54 production production NN cord-293714-s6ezxi5r 242 55 and and CC cord-293714-s6ezxi5r 242 56 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 242 57 of of IN cord-293714-s6ezxi5r 242 58 the the DT cord-293714-s6ezxi5r 242 59 tumor tumor NN cord-293714-s6ezxi5r 242 60 necrosis necrosis NN cord-293714-s6ezxi5r 242 61 factor factor NN cord-293714-s6ezxi5r 242 62 - - HYPH cord-293714-s6ezxi5r 242 63 alpha alpha NN cord-293714-s6ezxi5r 242 64 gene gene NN cord-293714-s6ezxi5r 242 65 in in IN cord-293714-s6ezxi5r 242 66 individuals individual NNS cord-293714-s6ezxi5r 242 67 with with IN cord-293714-s6ezxi5r 242 68 a a DT cord-293714-s6ezxi5r 242 69 history history NN cord-293714-s6ezxi5r 242 70 of of IN cord-293714-s6ezxi5r 242 71 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 242 72 disease disease NN cord-293714-s6ezxi5r 242 73 Association Association NNP cord-293714-s6ezxi5r 242 74 between between IN cord-293714-s6ezxi5r 242 75 levels level NNS cord-293714-s6ezxi5r 242 76 of of IN cord-293714-s6ezxi5r 242 77 TNF tnf NN cord-293714-s6ezxi5r 242 78 - - HYPH cord-293714-s6ezxi5r 242 79 alpha alpha NNP cord-293714-s6ezxi5r 242 80 and and CC cord-293714-s6ezxi5r 242 81 TNF tnf NN cord-293714-s6ezxi5r 242 82 - - HYPH cord-293714-s6ezxi5r 242 83 alpha alpha NN cord-293714-s6ezxi5r 242 84 promoter promoter NN cord-293714-s6ezxi5r 242 85 -308 -308 NN cord-293714-s6ezxi5r 243 1 A/ A/ NNP cord-293714-s6ezxi5r 244 1 A a DT cord-293714-s6ezxi5r 244 2 polymorphism polymorphism NN cord-293714-s6ezxi5r 244 3 in in IN cord-293714-s6ezxi5r 244 4 children child NNS cord-293714-s6ezxi5r 244 5 with with IN cord-293714-s6ezxi5r 244 6 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 244 7 disease disease NN cord-293714-s6ezxi5r 244 8 Tumor tumor NN cord-293714-s6ezxi5r 244 9 necrosis necrosis NN cord-293714-s6ezxi5r 244 10 factor factor NN cord-293714-s6ezxi5r 244 11 - - HYPH cord-293714-s6ezxi5r 244 12 alpha alpha NN cord-293714-s6ezxi5r 244 13 levels level NNS cord-293714-s6ezxi5r 244 14 and and CC cord-293714-s6ezxi5r 244 15 promoter promoter NN cord-293714-s6ezxi5r 244 16 polymorphism polymorphism NN cord-293714-s6ezxi5r 244 17 in in IN cord-293714-s6ezxi5r 244 18 patients patient NNS cord-293714-s6ezxi5r 244 19 with with IN cord-293714-s6ezxi5r 244 20 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 244 21 disease disease NN cord-293714-s6ezxi5r 244 22 in in IN cord-293714-s6ezxi5r 244 23 Korea Korea NNP cord-293714-s6ezxi5r 244 24 Association Association NNP cord-293714-s6ezxi5r 244 25 of of IN cord-293714-s6ezxi5r 244 26 vascular vascular JJ cord-293714-s6ezxi5r 244 27 endothelial endothelial JJ cord-293714-s6ezxi5r 244 28 growth growth NN cord-293714-s6ezxi5r 244 29 factor factor NN cord-293714-s6ezxi5r 244 30 ( ( -LRB- cord-293714-s6ezxi5r 244 31 VEGF VEGF NNP cord-293714-s6ezxi5r 244 32 ) ) -RRB- cord-293714-s6ezxi5r 244 33 and and CC cord-293714-s6ezxi5r 245 1 VEGF VEGF NNP cord-293714-s6ezxi5r 245 2 receptor receptor NN cord-293714-s6ezxi5r 245 3 gene gene NN cord-293714-s6ezxi5r 245 4 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 245 5 with with IN cord-293714-s6ezxi5r 245 6 coronary coronary JJ cord-293714-s6ezxi5r 245 7 artery artery NN cord-293714-s6ezxi5r 245 8 lesions lesion NNS cord-293714-s6ezxi5r 245 9 of of IN cord-293714-s6ezxi5r 245 10 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 245 11 disease disease NN cord-293714-s6ezxi5r 246 1 Vascular vascular JJ cord-293714-s6ezxi5r 246 2 endothelial endothelial JJ cord-293714-s6ezxi5r 246 3 growth growth NN cord-293714-s6ezxi5r 246 4 factor factor NN cord-293714-s6ezxi5r 246 5 gene gene NN cord-293714-s6ezxi5r 246 6 haplotypes haplotype NNS cord-293714-s6ezxi5r 246 7 in in IN cord-293714-s6ezxi5r 246 8 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 246 9 disease disease NN cord-293714-s6ezxi5r 246 10 Association Association NNP cord-293714-s6ezxi5r 246 11 of of IN cord-293714-s6ezxi5r 246 12 vascular vascular JJ cord-293714-s6ezxi5r 246 13 endothelial endothelial JJ cord-293714-s6ezxi5r 246 14 growth growth NN cord-293714-s6ezxi5r 246 15 factor factor NN cord-293714-s6ezxi5r 247 1 C-634 C-634 NNP cord-293714-s6ezxi5r 247 2 g g NN cord-293714-s6ezxi5r 247 3 polymorphism polymorphism NN cord-293714-s6ezxi5r 247 4 in in IN cord-293714-s6ezxi5r 247 5 Taiwanese taiwanese JJ cord-293714-s6ezxi5r 247 6 children child NNS cord-293714-s6ezxi5r 247 7 with with IN cord-293714-s6ezxi5r 247 8 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 247 9 disease disease NN cord-293714-s6ezxi5r 247 10 Lack Lack NNP cord-293714-s6ezxi5r 247 11 of of IN cord-293714-s6ezxi5r 247 12 association association NN cord-293714-s6ezxi5r 247 13 of of IN cord-293714-s6ezxi5r 247 14 the the DT cord-293714-s6ezxi5r 247 15 vascular vascular JJ cord-293714-s6ezxi5r 247 16 endothelial endothelial JJ cord-293714-s6ezxi5r 247 17 growth growth NN cord-293714-s6ezxi5r 247 18 factor factor NN cord-293714-s6ezxi5r 247 19 gene gene NN cord-293714-s6ezxi5r 247 20 polymorphisms polymorphism NNS cord-293714-s6ezxi5r 247 21 with with IN cord-293714-s6ezxi5r 247 22 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 247 23 disease disease NN cord-293714-s6ezxi5r 247 24 in in IN cord-293714-s6ezxi5r 247 25 Taiwanese taiwanese JJ cord-293714-s6ezxi5r 247 26 children child NNS cord-293714-s6ezxi5r 247 27 ITPKC ITPKC NNP cord-293714-s6ezxi5r 247 28 functional functional JJ cord-293714-s6ezxi5r 247 29 polymorphism polymorphism NN cord-293714-s6ezxi5r 247 30 associated associate VBN cord-293714-s6ezxi5r 247 31 with with IN cord-293714-s6ezxi5r 247 32 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 247 33 disease disease NN cord-293714-s6ezxi5r 247 34 susceptibility susceptibility NN cord-293714-s6ezxi5r 247 35 and and CC cord-293714-s6ezxi5r 247 36 formation formation NN cord-293714-s6ezxi5r 247 37 of of IN cord-293714-s6ezxi5r 247 38 coronary coronary JJ cord-293714-s6ezxi5r 247 39 artery artery NN cord-293714-s6ezxi5r 248 1 aneurysms aneurysm NNS cord-293714-s6ezxi5r 249 1 A a DT cord-293714-s6ezxi5r 249 2 genome genome NN cord-293714-s6ezxi5r 249 3 - - HYPH cord-293714-s6ezxi5r 249 4 wide wide JJ cord-293714-s6ezxi5r 249 5 association association NN cord-293714-s6ezxi5r 249 6 study study NN cord-293714-s6ezxi5r 249 7 identifies identify VBZ cord-293714-s6ezxi5r 249 8 novel novel JJ cord-293714-s6ezxi5r 249 9 and and CC cord-293714-s6ezxi5r 249 10 functionally functionally RB cord-293714-s6ezxi5r 249 11 related related JJ cord-293714-s6ezxi5r 249 12 susceptibility susceptibility NN cord-293714-s6ezxi5r 249 13 loci locus NNS cord-293714-s6ezxi5r 249 14 for for IN cord-293714-s6ezxi5r 249 15 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 249 16 disease disease NN cord-293714-s6ezxi5r 250 1 A a DT cord-293714-s6ezxi5r 250 2 genome genome NN cord-293714-s6ezxi5r 250 3 - - HYPH cord-293714-s6ezxi5r 250 4 wide wide JJ cord-293714-s6ezxi5r 250 5 association association NN cord-293714-s6ezxi5r 250 6 analysis analysis NN cord-293714-s6ezxi5r 250 7 reveals reveal VBZ cord-293714-s6ezxi5r 250 8 1p31 1p31 CD cord-293714-s6ezxi5r 250 9 and and CC cord-293714-s6ezxi5r 250 10 2p13.3 2p13.3 CD cord-293714-s6ezxi5r 250 11 as as IN cord-293714-s6ezxi5r 250 12 susceptibility susceptibility NN cord-293714-s6ezxi5r 250 13 loci locus NNS cord-293714-s6ezxi5r 250 14 for for IN cord-293714-s6ezxi5r 250 15 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 250 16 disease disease NN cord-293714-s6ezxi5r 250 17 Identification identification NN cord-293714-s6ezxi5r 250 18 of of IN cord-293714-s6ezxi5r 250 19 novel novel JJ cord-293714-s6ezxi5r 250 20 susceptibility susceptibility NN cord-293714-s6ezxi5r 250 21 loci locus NNS cord-293714-s6ezxi5r 250 22 for for IN cord-293714-s6ezxi5r 250 23 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 250 24 disease disease NN cord-293714-s6ezxi5r 250 25 in in IN cord-293714-s6ezxi5r 250 26 a a DT cord-293714-s6ezxi5r 250 27 Han Han NNP cord-293714-s6ezxi5r 250 28 Chinese chinese JJ cord-293714-s6ezxi5r 250 29 population population NN cord-293714-s6ezxi5r 250 30 by by IN cord-293714-s6ezxi5r 250 31 a a DT cord-293714-s6ezxi5r 250 32 genome genome NN cord-293714-s6ezxi5r 250 33 - - HYPH cord-293714-s6ezxi5r 250 34 wide wide JJ cord-293714-s6ezxi5r 250 35 association association NN cord-293714-s6ezxi5r 250 36 study study NN cord-293714-s6ezxi5r 250 37 Genome Genome NNP cord-293714-s6ezxi5r 250 38 - - HYPH cord-293714-s6ezxi5r 250 39 wide wide JJ cord-293714-s6ezxi5r 250 40 association association NN cord-293714-s6ezxi5r 250 41 study study NN cord-293714-s6ezxi5r 250 42 identifies identify VBZ cord-293714-s6ezxi5r 250 43 FCGR2A fcgr2a NN cord-293714-s6ezxi5r 250 44 as as IN cord-293714-s6ezxi5r 250 45 a a DT cord-293714-s6ezxi5r 250 46 susceptibility susceptibility NN cord-293714-s6ezxi5r 250 47 locus locus NN cord-293714-s6ezxi5r 250 48 for for IN cord-293714-s6ezxi5r 250 49 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 250 50 disease disease NN cord-293714-s6ezxi5r 251 1 A a DT cord-293714-s6ezxi5r 251 2 genome genome NN cord-293714-s6ezxi5r 251 3 - - HYPH cord-293714-s6ezxi5r 251 4 wide wide JJ cord-293714-s6ezxi5r 251 5 association association NN cord-293714-s6ezxi5r 251 6 study study NN cord-293714-s6ezxi5r 251 7 identifies identify VBZ cord-293714-s6ezxi5r 251 8 three three CD cord-293714-s6ezxi5r 251 9 new new JJ cord-293714-s6ezxi5r 251 10 risk risk NN cord-293714-s6ezxi5r 251 11 loci locus NNS cord-293714-s6ezxi5r 251 12 for for IN cord-293714-s6ezxi5r 251 13 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 251 14 disease disease NN cord-293714-s6ezxi5r 251 15 Two two CD cord-293714-s6ezxi5r 251 16 new new JJ cord-293714-s6ezxi5r 251 17 susceptibility susceptibility NN cord-293714-s6ezxi5r 251 18 loci locus NNS cord-293714-s6ezxi5r 251 19 for for IN cord-293714-s6ezxi5r 251 20 Kawasaki Kawasaki NNP cord-293714-s6ezxi5r 251 21 disease disease NN cord-293714-s6ezxi5r 251 22 identified identify VBN cord-293714-s6ezxi5r 251 23 through through IN cord-293714-s6ezxi5r 251 24 genome genome NN cord-293714-s6ezxi5r 251 25 - - HYPH cord-293714-s6ezxi5r 251 26 wide wide JJ cord-293714-s6ezxi5r 251 27 association association NN cord-293714-s6ezxi5r 251 28 analysis analysis NN cord-293714-s6ezxi5r 251 29 This this DT cord-293714-s6ezxi5r 251 30 review review NN cord-293714-s6ezxi5r 251 31 was be VBD cord-293714-s6ezxi5r 251 32 supported support VBN cord-293714-s6ezxi5r 251 33 by by IN cord-293714-s6ezxi5r 251 34 a a DT cord-293714-s6ezxi5r 251 35 grant grant NN cord-293714-s6ezxi5r 251 36 from from IN cord-293714-s6ezxi5r 251 37 the the DT cord-293714-s6ezxi5r 251 38 Italian italian JJ cord-293714-s6ezxi5r 251 39 Ministry Ministry NNP cord-293714-s6ezxi5r 251 40 of of IN cord-293714-s6ezxi5r 251 41 Health Health NNP cord-293714-s6ezxi5r 251 42 ( ( -LRB- cord-293714-s6ezxi5r 251 43 Bando Bando NNP cord-293714-s6ezxi5r 251 44 Giovani Giovani NNP cord-293714-s6ezxi5r 251 45 Ricercatori Ricercatori NNP cord-293714-s6ezxi5r 251 46 2007 2007 CD cord-293714-s6ezxi5r 251 47 ) ) -RRB- cord-293714-s6ezxi5r 251 48 . . . cord-293714-s6ezxi5r 252 1 The the DT cord-293714-s6ezxi5r 252 2 authors author NNS cord-293714-s6ezxi5r 252 3 have have VBP cord-293714-s6ezxi5r 252 4 no no DT cord-293714-s6ezxi5r 252 5 potential potential JJ cord-293714-s6ezxi5r 252 6 conflict conflict NN cord-293714-s6ezxi5r 252 7 of of IN cord-293714-s6ezxi5r 252 8 interest interest NN cord-293714-s6ezxi5r 252 9 to to TO cord-293714-s6ezxi5r 252 10 declare declare VB cord-293714-s6ezxi5r 252 11 . . .