id author title date pages extension mime words sentences flesch summary cache txt cord-018318-vzzrsqsn Naidu, C. Sudeep Postoperative Liver Failure 2017-02-08 .txt text/plain 9063 524 42 They focussed on serum bilirubin (SB) and prothrombin time (PT) as important prognostic markers of postoperative liver functional status and proposed the '50-50' criteria for the defi nition of PLF, i.e. the combination of PT >50 % of baseline normal and SB >50 μmol/L on postoperative day (POD) 5 (the '50-50' criteria) was found to be strongly predictive of mortality. In a study, mortality was signifi cantly higher in patients who had resection of hepatocellular carcinoma (HCC) in cirrhosis associated with active hepatitis (8.7 versus 1.5 %; p < 0.05) [ 13 ] . PLF and postoperative renal dysfunction are independent predictors of 90-day mortality following liver resection but the predictive value for mortality is significantly higher when both systems fail simultaneously. The patient's liver status, hepatic reserve potential and functional aspect need to be investigated along with the metabolic and haematological derangements, which may lead to PLF. ./cache/cord-018318-vzzrsqsn.txt ./txt/cord-018318-vzzrsqsn.txt