id author title date pages extension mime words sentences flesch summary cache txt cord-025168-be7zube4 Saleh, Mahshid Perspective of placenta derived mesenchymal stem cells in acute liver failure 2020-05-24 .txt text/plain 6533 361 41 Adipose tissue-derived mesenchymal stem cells (AD-MSCs) are isolated from adipose tissue by liposuction, are capable of differentiation to hepatocytelike cells in the presence of HGF, FGF-1, and FGF-4 factors and participate in the regeneration of hepatocytes and vasculogenesis [61] . Several studies have shown that MSCs secrete tropic factors and can be effective in reducing inflammation, fibrosis and apoptosis of liver cells as well as repairing damaged tissue by stimulating angiogenesis [74] . It can be argued that the beneficial effects of MSCs in liver diseases (including ALF) are not limited to hepatocyte repair, but rather the tropical factors released by Fig. 1 Mesenchymal stem cells and its effects on acute liver failure them modulate the deleterious effects of the immune response [142] . Bone marrow-derived mesenchymal stem cells inhibits hepatocyte apoptosis after acute liver injury In vivo hepatic differentiation potential of human umbilical cord-derived mesenchymal stem cells: therapeutic effect on liver fibrosis/cirrhosis ./cache/cord-025168-be7zube4.txt ./txt/cord-025168-be7zube4.txt