id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-033914-a9e3rncp	Kauffman-Ortega, E.	In memoriam Ludwig van Beethoven. Clinical history and possible diagnoses of the genius of musical composition in silence()	2020-10-17		.txt	text/plain	1721	93	48	His paternal grandmother, Josepha, and his father, Johann van Beethoven, suffered from alcohol use disorder, which led to his father's death when Ludwig was 21 years old. 1 Numerous pathologies in the differential diagnosis have been proposed for Beethoven's sensorineural hearing loss, and the most sustainable are: 1) lead poisoning, based on the presence of residuals of lead 100 times higher than normal in his hair and bones, according to an analysis performed in the United States in the mid 1990s, 4 2) Cogan's syndrome, characterized by bilateral sensorineural hearing loss and interstitial keratitis secondary to vasculitis, albeit there is no evidence of vestibular dysfunction in Beethoven's texts; that syndrome can be associated with idiopathic inflammatory bowel disease and reactive arthritis, 5 and 3) Paget's disease is supported by the frontal bone prominence, tinnitus, and headache. Alcohol consumption appears to be the most probable cause of Beethoven's cirrhosis of the liver, despite the macronodular appearance described in the autopsy.	./cache/cord-033914-a9e3rncp.txt	./txt/cord-033914-a9e3rncp.txt