id sid tid token lemma pos cord-303046-unksl7p4 1 1 key key NN cord-303046-unksl7p4 1 2 : : : cord-303046-unksl7p4 1 3 cord-303046-unksl7p4 cord-303046-unksl7p4 NN cord-303046-unksl7p4 1 4 authors author NNS cord-303046-unksl7p4 1 5 : : : cord-303046-unksl7p4 1 6 Pawlotsky Pawlotsky NNP cord-303046-unksl7p4 1 7 , , , cord-303046-unksl7p4 1 8 Jean Jean NNP cord-303046-unksl7p4 1 9 - - HYPH cord-303046-unksl7p4 1 10 Michel Michel NNP cord-303046-unksl7p4 1 11 title title NN cord-303046-unksl7p4 1 12 : : : cord-303046-unksl7p4 1 13 COVID-19 covid-19 VB cord-303046-unksl7p4 1 14 and and CC cord-303046-unksl7p4 1 15 the the DT cord-303046-unksl7p4 1 16 liver liver NN cord-303046-unksl7p4 1 17 - - HYPH cord-303046-unksl7p4 1 18 related relate VBN cord-303046-unksl7p4 1 19 deaths death NNS cord-303046-unksl7p4 1 20 to to TO cord-303046-unksl7p4 1 21 come come VB cord-303046-unksl7p4 1 22 date date NN cord-303046-unksl7p4 1 23 : : : cord-303046-unksl7p4 1 24 2020 2020 CD cord-303046-unksl7p4 1 25 - - HYPH cord-303046-unksl7p4 1 26 06 06 CD cord-303046-unksl7p4 1 27 - - HYPH cord-303046-unksl7p4 1 28 11 11 CD cord-303046-unksl7p4 1 29 journal journal NN cord-303046-unksl7p4 1 30 : : : cord-303046-unksl7p4 2 1 Nat Nat NNP cord-303046-unksl7p4 2 2 Rev Rev NNP cord-303046-unksl7p4 2 3 Gastroenterol Gastroenterol NNP cord-303046-unksl7p4 3 1 Hepatol Hepatol NNP cord-303046-unksl7p4 3 2 DOI DOI NNP cord-303046-unksl7p4 3 3 : : : cord-303046-unksl7p4 3 4 10.1038 10.1038 CD cord-303046-unksl7p4 3 5 / / SYM cord-303046-unksl7p4 3 6 s41575 s41575 NN cord-303046-unksl7p4 3 7 - - HYPH cord-303046-unksl7p4 3 8 020 020 CD cord-303046-unksl7p4 4 1 -0328 -0328 NNP cord-303046-unksl7p4 4 2 - - CD cord-303046-unksl7p4 4 3 2 2 CD cord-303046-unksl7p4 5 1 sha sha NNP cord-303046-unksl7p4 5 2 : : : cord-303046-unksl7p4 5 3 ba423308a3ca2c5f2eeda5b790dab83af9e30381 ba423308a3ca2c5f2eeda5b790dab83af9e30381 NNP cord-303046-unksl7p4 5 4 doc_id doc_id CD cord-303046-unksl7p4 5 5 : : : cord-303046-unksl7p4 5 6 303046 303046 CD cord-303046-unksl7p4 5 7 cord_uid cord_uid NNS cord-303046-unksl7p4 5 8 : : : cord-303046-unksl7p4 6 1 unksl7p4 unksl7p4 NNP cord-303046-unksl7p4 6 2 Coronavirus Coronavirus NNP cord-303046-unksl7p4 6 3 disease disease NN cord-303046-unksl7p4 6 4 2019 2019 CD cord-303046-unksl7p4 6 5 ( ( -LRB- cord-303046-unksl7p4 6 6 COVID-19 COVID-19 NNP cord-303046-unksl7p4 6 7 ) ) -RRB- cord-303046-unksl7p4 6 8 itself -PRON- PRP cord-303046-unksl7p4 7 1 and/or and/or CC cord-303046-unksl7p4 8 1 the the DT cord-303046-unksl7p4 8 2 use use NN cord-303046-unksl7p4 8 3 of of IN cord-303046-unksl7p4 8 4 hepatotoxic hepatotoxic JJ cord-303046-unksl7p4 8 5 drugs drug NNS cord-303046-unksl7p4 8 6 might may MD cord-303046-unksl7p4 8 7 negatively negatively RB cord-303046-unksl7p4 8 8 affect affect VB cord-303046-unksl7p4 8 9 the the DT cord-303046-unksl7p4 8 10 course course NN cord-303046-unksl7p4 8 11 and and CC cord-303046-unksl7p4 8 12 management management NN cord-303046-unksl7p4 8 13 of of IN cord-303046-unksl7p4 8 14 patients patient NNS cord-303046-unksl7p4 8 15 with with IN cord-303046-unksl7p4 8 16 pre pre JJ cord-303046-unksl7p4 8 17 - - JJ cord-303046-unksl7p4 8 18 existing existing JJ cord-303046-unksl7p4 8 19 chronic chronic JJ cord-303046-unksl7p4 8 20 liver liver NN cord-303046-unksl7p4 8 21 diseases disease NNS cord-303046-unksl7p4 8 22 . . . cord-303046-unksl7p4 9 1 However however RB cord-303046-unksl7p4 9 2 , , , cord-303046-unksl7p4 9 3 the the DT cord-303046-unksl7p4 9 4 greatest great JJS cord-303046-unksl7p4 9 5 effect effect NN cord-303046-unksl7p4 9 6 of of IN cord-303046-unksl7p4 9 7 COVID-19 COVID-19 NNP cord-303046-unksl7p4 9 8 on on IN cord-303046-unksl7p4 9 9 liver liver NN cord-303046-unksl7p4 9 10 diseases disease NNS cord-303046-unksl7p4 9 11 will will MD cord-303046-unksl7p4 9 12 be be VB cord-303046-unksl7p4 9 13 indirect indirect JJ cord-303046-unksl7p4 9 14 and and CC cord-303046-unksl7p4 9 15 delayed delay VBN cord-303046-unksl7p4 9 16 , , , cord-303046-unksl7p4 9 17 resulting result VBG cord-303046-unksl7p4 9 18 from from IN cord-303046-unksl7p4 9 19 the the DT cord-303046-unksl7p4 9 20 impending impending JJ cord-303046-unksl7p4 9 21 global global JJ cord-303046-unksl7p4 9 22 economic economic JJ cord-303046-unksl7p4 9 23 crisis crisis NN cord-303046-unksl7p4 9 24 . . . cord-303046-unksl7p4 10 1 Coronavirus Coronavirus NNP cord-303046-unksl7p4 10 2 disease disease NN cord-303046-unksl7p4 10 3 2019 2019 CD cord-303046-unksl7p4 10 4 ( ( -LRB- cord-303046-unksl7p4 10 5 COVID-19 COVID-19 NNP cord-303046-unksl7p4 10 6 ) ) -RRB- cord-303046-unksl7p4 10 7 was be VBD cord-303046-unksl7p4 10 8 first first RB cord-303046-unksl7p4 10 9 reported report VBN cord-303046-unksl7p4 10 10 in in IN cord-303046-unksl7p4 10 11 December December NNP cord-303046-unksl7p4 10 12 2019 2019 CD cord-303046-unksl7p4 10 13 in in IN cord-303046-unksl7p4 10 14 Wuhan Wuhan NNP cord-303046-unksl7p4 10 15 , , , cord-303046-unksl7p4 10 16 China China NNP cord-303046-unksl7p4 10 17 and and CC cord-303046-unksl7p4 10 18 was be VBD cord-303046-unksl7p4 10 19 considered consider VBN cord-303046-unksl7p4 10 20 harmless harmless JJ cord-303046-unksl7p4 10 21 by by IN cord-303046-unksl7p4 10 22 many many JJ cord-303046-unksl7p4 10 23 observers observer NNS cord-303046-unksl7p4 10 24 . . . cord-303046-unksl7p4 11 1 As as IN cord-303046-unksl7p4 11 2 of of IN cord-303046-unksl7p4 11 3 May May NNP cord-303046-unksl7p4 11 4 30th 30th NN cord-303046-unksl7p4 11 5 2020 2020 CD cord-303046-unksl7p4 11 6 , , , cord-303046-unksl7p4 11 7 according accord VBG cord-303046-unksl7p4 11 8 to to IN cord-303046-unksl7p4 11 9 the the DT cord-303046-unksl7p4 11 10 COVID-19 COVID-19 NNP cord-303046-unksl7p4 11 11 Dashboard Dashboard NNP cord-303046-unksl7p4 11 12 by by IN cord-303046-unksl7p4 11 13 the the DT cord-303046-unksl7p4 11 14 Center Center NNP cord-303046-unksl7p4 11 15 for for IN cord-303046-unksl7p4 11 16 Systems Systems NNP cord-303046-unksl7p4 11 17 Science Science NNP cord-303046-unksl7p4 11 18 and and CC cord-303046-unksl7p4 11 19 Engineering Engineering NNP cord-303046-unksl7p4 11 20 at at IN cord-303046-unksl7p4 11 21 Johns Johns NNP cord-303046-unksl7p4 11 22 Hopkins Hopkins NNP cord-303046-unksl7p4 11 23 University University NNP cord-303046-unksl7p4 11 24 , , , cord-303046-unksl7p4 11 25 USA USA NNP cord-303046-unksl7p4 11 26 , , , cord-303046-unksl7p4 11 27 six six CD cord-303046-unksl7p4 11 28 million million CD cord-303046-unksl7p4 11 29 people people NNS cord-303046-unksl7p4 11 30 worldwide worldwide RB cord-303046-unksl7p4 11 31 have have VBP cord-303046-unksl7p4 11 32 been be VBN cord-303046-unksl7p4 11 33 diagnosed diagnose VBN cord-303046-unksl7p4 11 34 with with IN cord-303046-unksl7p4 11 35 COVID-19 COVID-19 NNP cord-303046-unksl7p4 11 36 and and CC cord-303046-unksl7p4 11 37 more more JJR cord-303046-unksl7p4 11 38 than than IN cord-303046-unksl7p4 11 39 365,000 365,000 CD cord-303046-unksl7p4 11 40 of of IN cord-303046-unksl7p4 11 41 them -PRON- PRP cord-303046-unksl7p4 11 42 have have VBP cord-303046-unksl7p4 11 43 died die VBN cord-303046-unksl7p4 11 44 from from IN cord-303046-unksl7p4 11 45 its -PRON- PRP$ cord-303046-unksl7p4 11 46 complications complication NNS cord-303046-unksl7p4 11 47 . . . cord-303046-unksl7p4 12 1 Meanwhile meanwhile RB cord-303046-unksl7p4 12 2 , , , cord-303046-unksl7p4 12 3 the the DT cord-303046-unksl7p4 12 4 world world NN cord-303046-unksl7p4 12 5 economy economy NN cord-303046-unksl7p4 12 6 is be VBZ cord-303046-unksl7p4 12 7 collapsing collapse VBG cord-303046-unksl7p4 12 8 . . . cord-303046-unksl7p4 13 1 COVID-19 COVID-19 NNP cord-303046-unksl7p4 13 2 , , , cord-303046-unksl7p4 13 3 which which WDT cord-303046-unksl7p4 13 4 is be VBZ cord-303046-unksl7p4 13 5 caused cause VBN cord-303046-unksl7p4 13 6 by by IN cord-303046-unksl7p4 13 7 severe severe JJ cord-303046-unksl7p4 13 8 acute acute JJ cord-303046-unksl7p4 13 9 respiratory respiratory JJ cord-303046-unksl7p4 13 10 syndrome syndrome NN cord-303046-unksl7p4 13 11 coronavirus coronavirus NN cord-303046-unksl7p4 13 12 2 2 CD cord-303046-unksl7p4 14 1 ( ( -LRB- cord-303046-unksl7p4 14 2 SARS SARS NNP cord-303046-unksl7p4 14 3 - - HYPH cord-303046-unksl7p4 14 4 CoV-2 CoV-2 NNP cord-303046-unksl7p4 14 5 ) ) -RRB- cord-303046-unksl7p4 14 6 , , , cord-303046-unksl7p4 14 7 was be VBD cord-303046-unksl7p4 14 8 initially initially RB cord-303046-unksl7p4 14 9 thought think VBN cord-303046-unksl7p4 14 10 to to TO cord-303046-unksl7p4 14 11 present present VB cord-303046-unksl7p4 14 12 essentially essentially RB cord-303046-unksl7p4 14 13 as as IN cord-303046-unksl7p4 14 14 an an DT cord-303046-unksl7p4 14 15 upper upper NN cord-303046-unksl7p4 14 16 and/or and/or CC cord-303046-unksl7p4 14 17 lower low JJR cord-303046-unksl7p4 14 18 respiratory respiratory JJ cord-303046-unksl7p4 14 19 tract tract NN cord-303046-unksl7p4 14 20 infection infection NN cord-303046-unksl7p4 14 21 . . . cord-303046-unksl7p4 15 1 We -PRON- PRP cord-303046-unksl7p4 15 2 now now RB cord-303046-unksl7p4 15 3 know know VBP cord-303046-unksl7p4 15 4 that that IN cord-303046-unksl7p4 15 5 SARS SARS NNP cord-303046-unksl7p4 15 6 - - HYPH cord-303046-unksl7p4 15 7 CoV-2 CoV-2 NNP cord-303046-unksl7p4 15 8 induces induce VBZ cord-303046-unksl7p4 15 9 a a DT cord-303046-unksl7p4 15 10 systemic systemic JJ cord-303046-unksl7p4 15 11 disease disease NN cord-303046-unksl7p4 15 12 attacking attack VBG cord-303046-unksl7p4 15 13 many many JJ cord-303046-unksl7p4 15 14 organs organ NNS cord-303046-unksl7p4 15 15 , , , cord-303046-unksl7p4 15 16 potentially potentially RB cord-303046-unksl7p4 15 17 causing cause VBG cord-303046-unksl7p4 15 18 major major JJ cord-303046-unksl7p4 15 19 damage damage NN cord-303046-unksl7p4 15 20 , , , cord-303046-unksl7p4 15 21 including include VBG cord-303046-unksl7p4 15 22 mortality mortality NN cord-303046-unksl7p4 15 23 , , , cord-303046-unksl7p4 15 24 and and CC cord-303046-unksl7p4 15 25 long long JJ cord-303046-unksl7p4 15 26 - - HYPH cord-303046-unksl7p4 15 27 term term NN cord-303046-unksl7p4 15 28 sequelae sequela NNS cord-303046-unksl7p4 15 29 . . . cord-303046-unksl7p4 16 1 Surprisingly surprisingly RB cord-303046-unksl7p4 16 2 , , , cord-303046-unksl7p4 16 3 the the DT cord-303046-unksl7p4 16 4 liver liver NN cord-303046-unksl7p4 16 5 seems seem VBZ cord-303046-unksl7p4 16 6 to to TO cord-303046-unksl7p4 16 7 be be VB cord-303046-unksl7p4 16 8 relatively relatively RB cord-303046-unksl7p4 16 9 spared spare VBN cord-303046-unksl7p4 16 10 by by IN cord-303046-unksl7p4 16 11 the the DT cord-303046-unksl7p4 16 12 virus virus NN cord-303046-unksl7p4 16 13 . . . cord-303046-unksl7p4 17 1 Indeed indeed RB cord-303046-unksl7p4 17 2 , , , cord-303046-unksl7p4 17 3 apart apart RB cord-303046-unksl7p4 17 4 from from IN cord-303046-unksl7p4 17 5 patients patient NNS cord-303046-unksl7p4 17 6 with with IN cord-303046-unksl7p4 17 7 the the DT cord-303046-unksl7p4 17 8 most most RBS cord-303046-unksl7p4 17 9 severe severe JJ cord-303046-unksl7p4 17 10 forms form NNS cord-303046-unksl7p4 17 11 of of IN cord-303046-unksl7p4 17 12 the the DT cord-303046-unksl7p4 17 13 disease disease NN cord-303046-unksl7p4 17 14 resulting result VBG cord-303046-unksl7p4 17 15 from from IN cord-303046-unksl7p4 17 16 so so RB cord-303046-unksl7p4 17 17 - - HYPH cord-303046-unksl7p4 17 18 called call VBN cord-303046-unksl7p4 17 19 cytokine cytokine NN cord-303046-unksl7p4 17 20 storm storm NN cord-303046-unksl7p4 17 21 , , , cord-303046-unksl7p4 17 22 who who WP cord-303046-unksl7p4 17 23 die die VBP cord-303046-unksl7p4 17 24 from from IN cord-303046-unksl7p4 17 25 multivisceral multivisceral JJ cord-303046-unksl7p4 17 26 deficiencies deficiency NNS cord-303046-unksl7p4 17 27 including include VBG cord-303046-unksl7p4 17 28 the the DT cord-303046-unksl7p4 17 29 liver liver NN cord-303046-unksl7p4 17 30 , , , cord-303046-unksl7p4 17 31 manifestations manifestation NNS cord-303046-unksl7p4 17 32 of of IN cord-303046-unksl7p4 17 33 the the DT cord-303046-unksl7p4 17 34 infection infection NN cord-303046-unksl7p4 17 35 in in IN cord-303046-unksl7p4 17 36 the the DT cord-303046-unksl7p4 17 37 liver liver NN cord-303046-unksl7p4 17 38 are be VBP cord-303046-unksl7p4 17 39 generally generally RB cord-303046-unksl7p4 17 40 mild mild JJ cord-303046-unksl7p4 17 41 and and CC cord-303046-unksl7p4 17 42 transient transient JJ cord-303046-unksl7p4 17 43 and and CC cord-303046-unksl7p4 17 44 have have VBP cord-303046-unksl7p4 17 45 no no DT cord-303046-unksl7p4 17 46 effect effect NN cord-303046-unksl7p4 17 47 on on IN cord-303046-unksl7p4 17 48 the the DT cord-303046-unksl7p4 17 49 course course NN cord-303046-unksl7p4 17 50 of of IN cord-303046-unksl7p4 17 51 COVID-19 COVID-19 NNP cord-303046-unksl7p4 17 52 disease disease NN cord-303046-unksl7p4 17 53 . . . cord-303046-unksl7p4 18 1 Studies study NNS cord-303046-unksl7p4 18 2 based base VBN cord-303046-unksl7p4 18 3 on on IN cord-303046-unksl7p4 18 4 single single JJ cord-303046-unksl7p4 18 5 - - HYPH cord-303046-unksl7p4 18 6 cell cell NN cord-303046-unksl7p4 18 7 RNA rna NN cord-303046-unksl7p4 18 8 sequencing sequencing NN cord-303046-unksl7p4 18 9 in in IN cord-303046-unksl7p4 18 10 healthy healthy JJ cord-303046-unksl7p4 18 11 liver liver NN cord-303046-unksl7p4 18 12 tissues tissue NNS cord-303046-unksl7p4 18 13 suggest suggest VBP cord-303046-unksl7p4 18 14 that that IN cord-303046-unksl7p4 18 15 the the DT cord-303046-unksl7p4 18 16 SARS SARS NNP cord-303046-unksl7p4 18 17 - - HYPH cord-303046-unksl7p4 18 18 CoV-2 CoV-2 NNP cord-303046-unksl7p4 18 19 cellular cellular JJ cord-303046-unksl7p4 18 20 receptor receptor NN cord-303046-unksl7p4 18 21 , , , cord-303046-unksl7p4 18 22 angiotensin angiotensin NN cord-303046-unksl7p4 18 23 - - HYPH cord-303046-unksl7p4 18 24 converting convert VBG cord-303046-unksl7p4 18 25 enzyme enzyme NN cord-303046-unksl7p4 18 26 2 2 CD cord-303046-unksl7p4 18 27 ( ( -LRB- cord-303046-unksl7p4 18 28 ACE2 ACE2 NNP cord-303046-unksl7p4 18 29 ) ) -RRB- cord-303046-unksl7p4 18 30 , , , cord-303046-unksl7p4 18 31 is be VBZ cord-303046-unksl7p4 18 32 present present JJ cord-303046-unksl7p4 18 33 mainly mainly RB cord-303046-unksl7p4 18 34 on on IN cord-303046-unksl7p4 18 35 cholangiocytes cholangiocyte NNS cord-303046-unksl7p4 18 36 , , , cord-303046-unksl7p4 18 37 whereas whereas IN cord-303046-unksl7p4 18 38 expression expression NN cord-303046-unksl7p4 18 39 is be VBZ cord-303046-unksl7p4 18 40 20-fold 20-fold JJ cord-303046-unksl7p4 18 41 lower low JJR cord-303046-unksl7p4 18 42 in in IN cord-303046-unksl7p4 18 43 hepatocytes hepatocyte NNS cord-303046-unksl7p4 18 44 and and CC cord-303046-unksl7p4 18 45 ACE2 ACE2 NNP cord-303046-unksl7p4 18 46 is be VBZ cord-303046-unksl7p4 18 47 not not RB cord-303046-unksl7p4 18 48 expressed express VBN cord-303046-unksl7p4 18 49 in in IN cord-303046-unksl7p4 18 50 Kupffer Kupffer NNP cord-303046-unksl7p4 18 51 cells cell NNS cord-303046-unksl7p4 18 52 or or CC cord-303046-unksl7p4 18 53 intrahepatic intrahepatic JJ cord-303046-unksl7p4 18 54 immune immune JJ cord-303046-unksl7p4 18 55 cells cell NNS cord-303046-unksl7p4 18 56 1,2 1,2 CD cord-303046-unksl7p4 18 57 . . . cord-303046-unksl7p4 19 1 The the DT cord-303046-unksl7p4 19 2 low low JJ cord-303046-unksl7p4 19 3 or or CC cord-303046-unksl7p4 19 4 lack lack NN cord-303046-unksl7p4 19 5 of of IN cord-303046-unksl7p4 19 6 expression expression NN cord-303046-unksl7p4 19 7 of of IN cord-303046-unksl7p4 19 8 ACE2 ACE2 NNP cord-303046-unksl7p4 19 9 in in IN cord-303046-unksl7p4 19 10 hepatocytes hepatocyte NNS cord-303046-unksl7p4 19 11 explains explain VBZ cord-303046-unksl7p4 19 12 that that IN cord-303046-unksl7p4 19 13 SARS SARS NNP cord-303046-unksl7p4 19 14 - - HYPH cord-303046-unksl7p4 19 15 CoV-2 CoV-2 NNP cord-303046-unksl7p4 19 16 does do VBZ cord-303046-unksl7p4 19 17 not not RB cord-303046-unksl7p4 19 18 actually actually RB cord-303046-unksl7p4 19 19 cause cause VB cord-303046-unksl7p4 19 20 viral viral JJ cord-303046-unksl7p4 19 21 hepatitis hepatitis NN cord-303046-unksl7p4 19 22 . . . cord-303046-unksl7p4 20 1 COVID-19 COVID-19 NNP cord-303046-unksl7p4 20 2 is be VBZ cord-303046-unksl7p4 20 3 gene gene NN cord-303046-unksl7p4 20 4 rally rally NN cord-303046-unksl7p4 20 5 associated associate VBN cord-303046-unksl7p4 20 6 with with IN cord-303046-unksl7p4 20 7 mild mild JJ cord-303046-unksl7p4 20 8 - - HYPH cord-303046-unksl7p4 20 9 to to IN cord-303046-unksl7p4 20 10 - - HYPH cord-303046-unksl7p4 20 11 moderate moderate JJ cord-303046-unksl7p4 20 12 elevations elevation NNS cord-303046-unksl7p4 20 13 of of IN cord-303046-unksl7p4 20 14 aspartate aspartate NN cord-303046-unksl7p4 20 15 aminotransferase aminotransferase NN cord-303046-unksl7p4 20 16 ( ( -LRB- cord-303046-unksl7p4 20 17 AST AST NNP cord-303046-unksl7p4 20 18 ) ) -RRB- cord-303046-unksl7p4 20 19 and and CC cord-303046-unksl7p4 20 20 , , , cord-303046-unksl7p4 20 21 to to IN cord-303046-unksl7p4 20 22 a a DT cord-303046-unksl7p4 20 23 lower low JJR cord-303046-unksl7p4 20 24 extent extent NN cord-303046-unksl7p4 20 25 , , , cord-303046-unksl7p4 20 26 alanine alanine JJ cord-303046-unksl7p4 20 27 aminotransferase aminotransferase NN cord-303046-unksl7p4 20 28 ( ( -LRB- cord-303046-unksl7p4 20 29 ALT ALT NNP cord-303046-unksl7p4 20 30 ) ) -RRB- cord-303046-unksl7p4 20 31 levels level NNS cord-303046-unksl7p4 20 32 , , , cord-303046-unksl7p4 20 33 which which WDT cord-303046-unksl7p4 20 34 are be VBP cord-303046-unksl7p4 20 35 more more RBR cord-303046-unksl7p4 20 36 frequent frequent JJ cord-303046-unksl7p4 20 37 in in IN cord-303046-unksl7p4 20 38 patients patient NNS cord-303046-unksl7p4 20 39 with with IN cord-303046-unksl7p4 20 40 severe severe JJ cord-303046-unksl7p4 20 41 disease disease NN cord-303046-unksl7p4 20 42 than than IN cord-303046-unksl7p4 20 43 in in IN cord-303046-unksl7p4 20 44 those those DT cord-303046-unksl7p4 20 45 with with IN cord-303046-unksl7p4 20 46 a a DT cord-303046-unksl7p4 20 47 benign benign JJ cord-303046-unksl7p4 20 48 outcome outcome NN cord-303046-unksl7p4 20 49 3 3 CD cord-303046-unksl7p4 20 50 . . . cord-303046-unksl7p4 21 1 Total total JJ cord-303046-unksl7p4 21 2 bilirubin bilirubin JJ cord-303046-unksl7p4 21 3 levels level NNS cord-303046-unksl7p4 21 4 can can MD cord-303046-unksl7p4 21 5 also also RB cord-303046-unksl7p4 21 6 be be VB cord-303046-unksl7p4 21 7 slightly slightly RB cord-303046-unksl7p4 21 8 elevated elevate VBN cord-303046-unksl7p4 21 9 , , , cord-303046-unksl7p4 21 10 whereas whereas IN cord-303046-unksl7p4 21 11 alkaline alkaline JJ cord-303046-unksl7p4 21 12 phosphatase phosphatase NN cord-303046-unksl7p4 21 13 and and CC cord-303046-unksl7p4 21 14 γ γ NN cord-303046-unksl7p4 21 15 - - HYPH cord-303046-unksl7p4 21 16 glutamyltransferase glutamyltransferase NN cord-303046-unksl7p4 21 17 elevations elevation NNS cord-303046-unksl7p4 21 18 have have VBP cord-303046-unksl7p4 21 19 been be VBN cord-303046-unksl7p4 21 20 rarely rarely RB cord-303046-unksl7p4 21 21 reported report VBN cord-303046-unksl7p4 21 22 3 3 CD cord-303046-unksl7p4 21 23 . . . cord-303046-unksl7p4 22 1 Nonspecific nonspecific JJ cord-303046-unksl7p4 22 2 histological histological JJ cord-303046-unksl7p4 22 3 changes change NNS cord-303046-unksl7p4 22 4 in in IN cord-303046-unksl7p4 22 5 the the DT cord-303046-unksl7p4 22 6 liver liver NN cord-303046-unksl7p4 22 7 have have VBP cord-303046-unksl7p4 22 8 been be VBN cord-303046-unksl7p4 22 9 described describe VBN cord-303046-unksl7p4 22 10 in in IN cord-303046-unksl7p4 22 11 small small JJ cord-303046-unksl7p4 22 12 autopsy autopsy JJ cord-303046-unksl7p4 22 13 series series NN cord-303046-unksl7p4 22 14 , , , cord-303046-unksl7p4 22 15 ranging range VBG cord-303046-unksl7p4 22 16 from from IN cord-303046-unksl7p4 22 17 moderate moderate JJ cord-303046-unksl7p4 22 18 microvesicular microvesicular JJ cord-303046-unksl7p4 22 19 steatosis steatosis NN cord-303046-unksl7p4 22 20 with with IN cord-303046-unksl7p4 22 21 mild mild JJ cord-303046-unksl7p4 22 22 , , , cord-303046-unksl7p4 22 23 mixed mixed JJ cord-303046-unksl7p4 22 24 lobular lobular NNP cord-303046-unksl7p4 22 25 and and CC cord-303046-unksl7p4 22 26 portal portal JJ cord-303046-unksl7p4 22 27 activity activity NN cord-303046-unksl7p4 22 28 to to IN cord-303046-unksl7p4 22 29 focal focal JJ cord-303046-unksl7p4 22 30 necrosis necrosis NN cord-303046-unksl7p4 22 31 , , , cord-303046-unksl7p4 22 32 with with IN cord-303046-unksl7p4 22 33 detection detection NN cord-303046-unksl7p4 22 34 of of IN cord-303046-unksl7p4 22 35 the the DT cord-303046-unksl7p4 22 36 virus virus NN cord-303046-unksl7p4 22 37 in in IN cord-303046-unksl7p4 22 38 the the DT cord-303046-unksl7p4 22 39 liver liver NN cord-303046-unksl7p4 22 40 in in IN cord-303046-unksl7p4 22 41 some some DT cord-303046-unksl7p4 22 42 cases case NNS cord-303046-unksl7p4 22 43 4 4 CD cord-303046-unksl7p4 22 44 . . . cord-303046-unksl7p4 23 1 Changes change NNS cord-303046-unksl7p4 23 2 in in IN cord-303046-unksl7p4 23 3 liver liver NN cord-303046-unksl7p4 23 4 biochemistry biochemistry NN cord-303046-unksl7p4 23 5 might may MD cord-303046-unksl7p4 23 6 result result VB cord-303046-unksl7p4 23 7 from from IN cord-303046-unksl7p4 23 8 the the DT cord-303046-unksl7p4 23 9 systemic systemic JJ cord-303046-unksl7p4 23 10 inflammatory inflammatory JJ cord-303046-unksl7p4 23 11 response response NN cord-303046-unksl7p4 23 12 , , , cord-303046-unksl7p4 23 13 pneumonia pneumonia NN cord-303046-unksl7p4 23 14 - - HYPH cord-303046-unksl7p4 23 15 induced induce VBN cord-303046-unksl7p4 23 16 hypoxaemia hypoxaemia NN cord-303046-unksl7p4 23 17 and/or and/or CC cord-303046-unksl7p4 23 18 drug drug NN cord-303046-unksl7p4 23 19 - - HYPH cord-303046-unksl7p4 23 20 induced induce VBN cord-303046-unksl7p4 23 21 hepatic hepatic JJ cord-303046-unksl7p4 23 22 injury injury NN cord-303046-unksl7p4 23 23 , , , cord-303046-unksl7p4 23 24 especially especially RB cord-303046-unksl7p4 23 25 in in IN cord-303046-unksl7p4 23 26 patients patient NNS cord-303046-unksl7p4 23 27 with with IN cord-303046-unksl7p4 23 28 severe severe JJ cord-303046-unksl7p4 23 29 forms form NNS cord-303046-unksl7p4 23 30 of of IN cord-303046-unksl7p4 23 31 COVID-19 covid-19 JJ cord-303046-unksl7p4 23 32 requiring require VBG cord-303046-unksl7p4 23 33 hospitalization hospitalization NN cord-303046-unksl7p4 23 34 . . . cord-303046-unksl7p4 24 1 The the DT cord-303046-unksl7p4 24 2 frequency frequency NN cord-303046-unksl7p4 24 3 of of IN cord-303046-unksl7p4 24 4 abnormal abnormal JJ cord-303046-unksl7p4 24 5 liver liver NN cord-303046-unksl7p4 24 6 tests test NNS cord-303046-unksl7p4 24 7 was be VBD cord-303046-unksl7p4 24 8 reported report VBN cord-303046-unksl7p4 24 9 to to TO cord-303046-unksl7p4 24 10 increase increase VB cord-303046-unksl7p4 24 11 during during IN cord-303046-unksl7p4 24 12 hospitalization hospitalization NN cord-303046-unksl7p4 24 13 , , , cord-303046-unksl7p4 24 14 possibly possibly RB cord-303046-unksl7p4 24 15 owing owe VBG cord-303046-unksl7p4 24 16 to to IN cord-303046-unksl7p4 24 17 the the DT cord-303046-unksl7p4 24 18 administration administration NN cord-303046-unksl7p4 24 19 of of IN cord-303046-unksl7p4 24 20 hepatotoxic hepatotoxic JJ cord-303046-unksl7p4 24 21 drugs drug NNS cord-303046-unksl7p4 24 22 , , , cord-303046-unksl7p4 24 23 including include VBG cord-303046-unksl7p4 24 24 antibiotics antibiotic NNS cord-303046-unksl7p4 24 25 , , , cord-303046-unksl7p4 24 26 nonsteroidal nonsteroidal JJ cord-303046-unksl7p4 24 27 anti anti JJ cord-303046-unksl7p4 24 28 - - JJ cord-303046-unksl7p4 24 29 inflammatory inflammatory JJ cord-303046-unksl7p4 24 30 drugs drug NNS cord-303046-unksl7p4 24 31 , , , cord-303046-unksl7p4 24 32 herbal herbal JJ cord-303046-unksl7p4 24 33 products product NNS cord-303046-unksl7p4 24 34 and and CC cord-303046-unksl7p4 24 35 antiviral antiviral JJ cord-303046-unksl7p4 24 36 agents agent NNS cord-303046-unksl7p4 24 37 , , , cord-303046-unksl7p4 24 38 such such JJ cord-303046-unksl7p4 24 39 as as IN cord-303046-unksl7p4 24 40 ribavirin ribavirin NN cord-303046-unksl7p4 24 41 , , , cord-303046-unksl7p4 24 42 interferons interferon NNS cord-303046-unksl7p4 24 43 , , , cord-303046-unksl7p4 24 44 or or CC cord-303046-unksl7p4 24 45 the the DT cord-303046-unksl7p4 24 46 fixed fix VBN cord-303046-unksl7p4 24 47 - - HYPH cord-303046-unksl7p4 24 48 dose dose NN cord-303046-unksl7p4 24 49 combination combination NN cord-303046-unksl7p4 24 50 of of IN cord-303046-unksl7p4 24 51 lopinavir lopinavir NNS cord-303046-unksl7p4 24 52 and and CC cord-303046-unksl7p4 24 53 ritonavir ritonavir NNP cord-303046-unksl7p4 24 54 5 5 CD cord-303046-unksl7p4 24 55 . . . cord-303046-unksl7p4 25 1 Elevations elevation NNS cord-303046-unksl7p4 25 2 in in IN cord-303046-unksl7p4 25 3 aminotransferase aminotransferase NN cord-303046-unksl7p4 25 4 levels level NNS cord-303046-unksl7p4 25 5 have have VBP cord-303046-unksl7p4 25 6 also also RB cord-303046-unksl7p4 25 7 been be VBN cord-303046-unksl7p4 25 8 occasionally occasionally RB cord-303046-unksl7p4 25 9 reported report VBN cord-303046-unksl7p4 25 10 with with IN cord-303046-unksl7p4 25 11 other other JJ cord-303046-unksl7p4 25 12 drugs drug NNS cord-303046-unksl7p4 25 13 used use VBN cord-303046-unksl7p4 25 14 in in IN cord-303046-unksl7p4 25 15 clinical clinical JJ cord-303046-unksl7p4 25 16 trials trial NNS cord-303046-unksl7p4 25 17 in in IN cord-303046-unksl7p4 25 18 patients patient NNS cord-303046-unksl7p4 25 19 with with IN cord-303046-unksl7p4 25 20 COVID-19 COVID-19 NNP cord-303046-unksl7p4 25 21 , , , cord-303046-unksl7p4 25 22 including include VBG cord-303046-unksl7p4 25 23 chloroquine chloroquine NN cord-303046-unksl7p4 25 24 and and CC cord-303046-unksl7p4 25 25 hydroxychloroquine hydroxychloroquine NN cord-303046-unksl7p4 25 26 , , , cord-303046-unksl7p4 25 27 azithromycin azithromycin NNP cord-303046-unksl7p4 25 28 , , , cord-303046-unksl7p4 25 29 remdesivir remdesivir NNP cord-303046-unksl7p4 25 30 , , , cord-303046-unksl7p4 25 31 favipiravir favipiravir NNP cord-303046-unksl7p4 25 32 , , , cord-303046-unksl7p4 25 33 camostat camostat NNP cord-303046-unksl7p4 25 34 or or CC cord-303046-unksl7p4 25 35 tocilizumab tocilizumab NN cord-303046-unksl7p4 25 36 . . . cord-303046-unksl7p4 26 1 However however RB cord-303046-unksl7p4 26 2 , , , cord-303046-unksl7p4 26 3 liver liver NN cord-303046-unksl7p4 26 4 test test NN cord-303046-unksl7p4 26 5 abnormalities abnormality NNS cord-303046-unksl7p4 26 6 disappear disappear VBP cord-303046-unksl7p4 26 7 when when WRB cord-303046-unksl7p4 26 8 the the DT cord-303046-unksl7p4 26 9 infection infection NN cord-303046-unksl7p4 26 10 recovers recover VBZ cord-303046-unksl7p4 26 11 and/or and/or CC cord-303046-unksl7p4 26 12 when when WRB cord-303046-unksl7p4 26 13 hepatotoxic hepatotoxic JJ cord-303046-unksl7p4 26 14 drugs drug NNS cord-303046-unksl7p4 26 15 are be VBP cord-303046-unksl7p4 26 16 removed remove VBN cord-303046-unksl7p4 26 17 . . . cord-303046-unksl7p4 27 1 Patients patient NNS cord-303046-unksl7p4 27 2 with with IN cord-303046-unksl7p4 27 3 chronic chronic JJ cord-303046-unksl7p4 27 4 liver liver NN cord-303046-unksl7p4 27 5 disease disease NN cord-303046-unksl7p4 27 6 do do VBP cord-303046-unksl7p4 27 7 not not RB cord-303046-unksl7p4 27 8 seem seem VB cord-303046-unksl7p4 27 9 to to TO cord-303046-unksl7p4 27 10 be be VB cord-303046-unksl7p4 27 11 at at IN cord-303046-unksl7p4 27 12 greater great JJR cord-303046-unksl7p4 27 13 risk risk NN cord-303046-unksl7p4 27 14 of of IN cord-303046-unksl7p4 27 15 acquiring acquire VBG cord-303046-unksl7p4 27 16 the the DT cord-303046-unksl7p4 27 17 infection infection NN cord-303046-unksl7p4 27 18 than than IN cord-303046-unksl7p4 27 19 other other JJ cord-303046-unksl7p4 27 20 indivi indivi JJ cord-303046-unksl7p4 27 21 duals dual NNS cord-303046-unksl7p4 27 22 in in IN cord-303046-unksl7p4 27 23 the the DT cord-303046-unksl7p4 27 24 general general JJ cord-303046-unksl7p4 27 25 population population NN cord-303046-unksl7p4 27 26 , , , cord-303046-unksl7p4 27 27 but but CC cord-303046-unksl7p4 27 28 the the DT cord-303046-unksl7p4 27 29 potential potential JJ cord-303046-unksl7p4 27 30 onset onset NN cord-303046-unksl7p4 27 31 of of IN cord-303046-unksl7p4 27 32 COVID-19 covid-19 NN cord-303046-unksl7p4 27 33 in in IN cord-303046-unksl7p4 27 34 these these DT cord-303046-unksl7p4 27 35 patients patient NNS cord-303046-unksl7p4 27 36 raises raise VBZ cord-303046-unksl7p4 27 37 two two CD cord-303046-unksl7p4 27 38 questions question NNS cord-303046-unksl7p4 27 39 : : : cord-303046-unksl7p4 27 40 will will MD cord-303046-unksl7p4 27 41 patients patient NNS cord-303046-unksl7p4 27 42 with with IN cord-303046-unksl7p4 27 43 chronic chronic JJ cord-303046-unksl7p4 27 44 liver liver NN cord-303046-unksl7p4 27 45 disease disease NN cord-303046-unksl7p4 27 46 develop develop VBP cord-303046-unksl7p4 27 47 a a DT cord-303046-unksl7p4 27 48 more more RBR cord-303046-unksl7p4 27 49 severe severe JJ cord-303046-unksl7p4 27 50 form form NN cord-303046-unksl7p4 27 51 of of IN cord-303046-unksl7p4 27 52 COVID-19 covid-19 NN cord-303046-unksl7p4 27 53 ; ; : cord-303046-unksl7p4 27 54 and and CC cord-303046-unksl7p4 27 55 will will MD cord-303046-unksl7p4 27 56 COVID-19 covid-19 VB cord-303046-unksl7p4 27 57 aggravate aggravate VB cord-303046-unksl7p4 27 58 the the DT cord-303046-unksl7p4 27 59 course course NN cord-303046-unksl7p4 27 60 of of IN cord-303046-unksl7p4 27 61 their -PRON- PRP$ cord-303046-unksl7p4 27 62 liver liver NN cord-303046-unksl7p4 27 63 disease disease NN cord-303046-unksl7p4 27 64 and and CC cord-303046-unksl7p4 27 65 induce induce VB cord-303046-unksl7p4 27 66 liver liver NN cord-303046-unksl7p4 27 67 - - HYPH cord-303046-unksl7p4 27 68 related relate VBN cord-303046-unksl7p4 27 69 mortality mortality NN cord-303046-unksl7p4 27 70 ? ? . cord-303046-unksl7p4 28 1 One one CD cord-303046-unksl7p4 28 2 study study NN cord-303046-unksl7p4 28 3 has have VBZ cord-303046-unksl7p4 28 4 suggested suggest VBN cord-303046-unksl7p4 28 5 that that IN cord-303046-unksl7p4 28 6 65 65 CD cord-303046-unksl7p4 28 7 patients patient NNS cord-303046-unksl7p4 28 8 with with IN cord-303046-unksl7p4 28 9 non non JJ cord-303046-unksl7p4 28 10 - - JJ cord-303046-unksl7p4 28 11 alcoholic alcoholic JJ cord-303046-unksl7p4 28 12 fatty fatty JJ cord-303046-unksl7p4 28 13 liver liver NN cord-303046-unksl7p4 28 14 disease disease NN cord-303046-unksl7p4 28 15 ( ( -LRB- cord-303046-unksl7p4 28 16 NAFLD NAFLD NNP cord-303046-unksl7p4 28 17 ) ) -RRB- cord-303046-unksl7p4 28 18 related relate VBN cord-303046-unksl7p4 28 19 to to IN cord-303046-unksl7p4 28 20 the the DT cord-303046-unksl7p4 28 21 metabolic metabolic JJ cord-303046-unksl7p4 28 22 syndrome syndrome NN cord-303046-unksl7p4 28 23 were be VBD cord-303046-unksl7p4 28 24 four four CD cord-303046-unksl7p4 28 25 times time NNS cord-303046-unksl7p4 28 26 more more RBR cord-303046-unksl7p4 28 27 likely likely JJ cord-303046-unksl7p4 28 28 to to TO cord-303046-unksl7p4 28 29 develop develop VB cord-303046-unksl7p4 28 30 severe severe JJ cord-303046-unksl7p4 28 31 manifestations manifestation NNS cord-303046-unksl7p4 28 32 of of IN cord-303046-unksl7p4 28 33 COVID-19 covid-19 CD cord-303046-unksl7p4 28 34 than than IN cord-303046-unksl7p4 28 35 65 65 CD cord-303046-unksl7p4 28 36 patients patient NNS cord-303046-unksl7p4 28 37 without without IN cord-303046-unksl7p4 28 38 NAFLD NAFLD NNP cord-303046-unksl7p4 28 39 , , , cord-303046-unksl7p4 28 40 regardless regardless RB cord-303046-unksl7p4 28 41 of of IN cord-303046-unksl7p4 28 42 the the DT cord-303046-unksl7p4 28 43 presence presence NN cord-303046-unksl7p4 28 44 of of IN cord-303046-unksl7p4 28 45 diabetes diabetes NN cord-303046-unksl7p4 28 46 5 5 CD cord-303046-unksl7p4 28 47 . . . cord-303046-unksl7p4 29 1 However however RB cord-303046-unksl7p4 29 2 , , , cord-303046-unksl7p4 29 3 it -PRON- PRP cord-303046-unksl7p4 29 4 is be VBZ cord-303046-unksl7p4 29 5 unclear unclear JJ cord-303046-unksl7p4 29 6 whether whether IN cord-303046-unksl7p4 29 7 NAFLD NAFLD NNP cord-303046-unksl7p4 29 8 itself -PRON- PRP cord-303046-unksl7p4 29 9 plays play VBZ cord-303046-unksl7p4 29 10 a a DT cord-303046-unksl7p4 29 11 part part NN cord-303046-unksl7p4 29 12 , , , cord-303046-unksl7p4 29 13 rather rather RB cord-303046-unksl7p4 29 14 than than IN cord-303046-unksl7p4 29 15 the the DT cord-303046-unksl7p4 29 16 associated associate VBN cord-303046-unksl7p4 29 17 metabolic metabolic JJ cord-303046-unksl7p4 29 18 comorbidities comorbiditie NNS cord-303046-unksl7p4 29 19 that that WDT cord-303046-unksl7p4 29 20 include include VBP cord-303046-unksl7p4 29 21 obesity obesity NN cord-303046-unksl7p4 29 22 , , , cord-303046-unksl7p4 29 23 diabetes diabetes NN cord-303046-unksl7p4 29 24 and and CC cord-303046-unksl7p4 29 25 hypertension hypertension NN cord-303046-unksl7p4 29 26 , , , cord-303046-unksl7p4 29 27 which which WDT cord-303046-unksl7p4 29 28 are be VBP cord-303046-unksl7p4 29 29 well well RB cord-303046-unksl7p4 29 30 - - HYPH cord-303046-unksl7p4 29 31 known know VBN cord-303046-unksl7p4 29 32 risk risk NN cord-303046-unksl7p4 29 33 factors factor NNS cord-303046-unksl7p4 29 34 for for IN cord-303046-unksl7p4 29 35 developing develop VBG cord-303046-unksl7p4 29 36 severe severe JJ cord-303046-unksl7p4 29 37 COVID-19 covid-19 NN cord-303046-unksl7p4 29 38 . . . cord-303046-unksl7p4 30 1 Patients patient NNS cord-303046-unksl7p4 30 2 with with IN cord-303046-unksl7p4 30 3 cirrhosis cirrhosis NN cord-303046-unksl7p4 30 4 seem seem VBP cord-303046-unksl7p4 30 5 to to TO cord-303046-unksl7p4 30 6 be be VB cord-303046-unksl7p4 30 7 at at IN cord-303046-unksl7p4 30 8 greater great JJR cord-303046-unksl7p4 30 9 risk risk NN cord-303046-unksl7p4 30 10 than than IN cord-303046-unksl7p4 30 11 other other JJ cord-303046-unksl7p4 30 12 individuals individual NNS cord-303046-unksl7p4 30 13 for for IN cord-303046-unksl7p4 30 14 severe severe JJ cord-303046-unksl7p4 30 15 COVID-19 covid-19 NN cord-303046-unksl7p4 30 16 and and CC cord-303046-unksl7p4 30 17 the the DT cord-303046-unksl7p4 30 18 occurrence occurrence NN cord-303046-unksl7p4 30 19 of of IN cord-303046-unksl7p4 30 20 complications complication NNS cord-303046-unksl7p4 30 21 , , , cord-303046-unksl7p4 30 22 including include VBG cord-303046-unksl7p4 30 23 mortality mortality NN cord-303046-unksl7p4 30 24 , , , cord-303046-unksl7p4 31 1 regardless regardless RB cord-303046-unksl7p4 31 2 of of IN cord-303046-unksl7p4 31 3 the the DT cord-303046-unksl7p4 31 4 aetiology aetiology NN cord-303046-unksl7p4 31 5 COVID-19 COVID-19 NNP cord-303046-unksl7p4 31 6 and and CC cord-303046-unksl7p4 31 7 the the DT cord-303046-unksl7p4 31 8 liver liver NN cord-303046-unksl7p4 31 9 - - HYPH cord-303046-unksl7p4 31 10 related relate VBN cord-303046-unksl7p4 31 11 deaths death NNS cord-303046-unksl7p4 31 12 to to TO cord-303046-unksl7p4 31 13 come come VB cord-303046-unksl7p4 31 14 www.nature.com/nrgastro www.nature.com/nrgastro NNP cord-303046-unksl7p4 31 15 of of IN cord-303046-unksl7p4 31 16 liver liver NN cord-303046-unksl7p4 31 17 disease disease NN cord-303046-unksl7p4 31 18 6 6 CD cord-303046-unksl7p4 31 19 , , , cord-303046-unksl7p4 31 20 7 7 CD cord-303046-unksl7p4 31 21 . . . cord-303046-unksl7p4 32 1 The the DT cord-303046-unksl7p4 32 2 risk risk NN cord-303046-unksl7p4 32 3 could could MD cord-303046-unksl7p4 32 4 also also RB cord-303046-unksl7p4 32 5 be be VB cord-303046-unksl7p4 32 6 increased increase VBN cord-303046-unksl7p4 32 7 in in IN cord-303046-unksl7p4 32 8 indivi indivi JJ cord-303046-unksl7p4 32 9 duals dual NNS cord-303046-unksl7p4 32 10 with with IN cord-303046-unksl7p4 32 11 decomp decomp NN cord-303046-unksl7p4 32 12 ensated ensated NNP cord-303046-unksl7p4 32 13 cirrhosis cirrhosis NNP cord-303046-unksl7p4 32 14 , , , cord-303046-unksl7p4 32 15 but but CC cord-303046-unksl7p4 32 16 few few JJ cord-303046-unksl7p4 32 17 cases case NNS cord-303046-unksl7p4 32 18 have have VBP cord-303046-unksl7p4 32 19 been be VBN cord-303046-unksl7p4 32 20 reported report VBN cord-303046-unksl7p4 32 21 . . . cord-303046-unksl7p4 33 1 Data datum NNS cord-303046-unksl7p4 33 2 from from IN cord-303046-unksl7p4 33 3 registries registry NNS cord-303046-unksl7p4 33 4 from from IN cord-303046-unksl7p4 33 5 a a DT cord-303046-unksl7p4 33 6 large large JJ cord-303046-unksl7p4 33 7 , , , cord-303046-unksl7p4 33 8 multicentre multicentre NNP cord-303046-unksl7p4 33 9 international international JJ cord-303046-unksl7p4 33 10 cohort cohort NN cord-303046-unksl7p4 33 11 of of IN cord-303046-unksl7p4 33 12 patients patient NNS cord-303046-unksl7p4 33 13 with with IN cord-303046-unksl7p4 33 14 chronic chronic JJ cord-303046-unksl7p4 33 15 liver liver NN cord-303046-unksl7p4 33 16 disease disease NN cord-303046-unksl7p4 33 17 suggest suggest VBP cord-303046-unksl7p4 33 18 that that IN cord-303046-unksl7p4 33 19 patients patient NNS cord-303046-unksl7p4 33 20 with with IN cord-303046-unksl7p4 33 21 compensated compensate VBN cord-303046-unksl7p4 33 22 cirrhosis cirrhosis NN cord-303046-unksl7p4 33 23 are be VBP cord-303046-unksl7p4 33 24 at at IN cord-303046-unksl7p4 33 25 increased increase VBN cord-303046-unksl7p4 33 26 risk risk NN cord-303046-unksl7p4 33 27 of of IN cord-303046-unksl7p4 33 28 decompensation decompensation NN cord-303046-unksl7p4 33 29 and and CC cord-303046-unksl7p4 33 30 death death NN cord-303046-unksl7p4 33 31 during during IN cord-303046-unksl7p4 33 32 the the DT cord-303046-unksl7p4 33 33 course course NN cord-303046-unksl7p4 33 34 of of IN cord-303046-unksl7p4 33 35 COVID-19 COVID-19 NNP cord-303046-unksl7p4 33 36 , , , cord-303046-unksl7p4 33 37 even even RB cord-303046-unksl7p4 33 38 in in IN cord-303046-unksl7p4 33 39 the the DT cord-303046-unksl7p4 33 40 absence absence NN cord-303046-unksl7p4 33 41 of of IN cord-303046-unksl7p4 33 42 respiratory respiratory JJ cord-303046-unksl7p4 33 43 symptoms symptom NNS cord-303046-unksl7p4 33 44 8 8 CD cord-303046-unksl7p4 33 45 . . . cord-303046-unksl7p4 34 1 The the DT cord-303046-unksl7p4 34 2 contribution contribution NN cord-303046-unksl7p4 34 3 of of IN cord-303046-unksl7p4 34 4 thromboembolic thromboembolic JJ cord-303046-unksl7p4 34 5 disorders disorder NNS cord-303046-unksl7p4 34 6 to to IN cord-303046-unksl7p4 34 7 liver liver NN cord-303046-unksl7p4 34 8 injury injury NN cord-303046-unksl7p4 34 9 in in IN cord-303046-unksl7p4 34 10 patients patient NNS cord-303046-unksl7p4 34 11 with with IN cord-303046-unksl7p4 34 12 the the DT cord-303046-unksl7p4 34 13 most most RBS cord-303046-unksl7p4 34 14 severe severe JJ cord-303046-unksl7p4 34 15 forms form NNS cord-303046-unksl7p4 34 16 of of IN cord-303046-unksl7p4 34 17 COVID-19 COVID-19 NNP cord-303046-unksl7p4 34 18 has have VBZ cord-303046-unksl7p4 34 19 been be VBN cord-303046-unksl7p4 34 20 suggested suggest VBN cord-303046-unksl7p4 34 21 4 4 CD cord-303046-unksl7p4 34 22 . . . cord-303046-unksl7p4 35 1 Such such JJ cord-303046-unksl7p4 35 2 thromboembolic thromboembolic JJ cord-303046-unksl7p4 35 3 events event NNS cord-303046-unksl7p4 35 4 might may MD cord-303046-unksl7p4 35 5 expose expose VB cord-303046-unksl7p4 35 6 patients patient NNS cord-303046-unksl7p4 35 7 with with IN cord-303046-unksl7p4 35 8 pre pre JJ cord-303046-unksl7p4 35 9 - - JJ cord-303046-unksl7p4 35 10 existing existing JJ cord-303046-unksl7p4 35 11 chronic chronic JJ cord-303046-unksl7p4 35 12 liver liver NN cord-303046-unksl7p4 35 13 disease disease NN cord-303046-unksl7p4 35 14 to to IN cord-303046-unksl7p4 35 15 serious serious JJ cord-303046-unksl7p4 35 16 hepatic hepatic JJ cord-303046-unksl7p4 35 17 complications complication NNS cord-303046-unksl7p4 35 18 . . . cord-303046-unksl7p4 36 1 As as IN cord-303046-unksl7p4 36 2 a a DT cord-303046-unksl7p4 36 3 result result NN cord-303046-unksl7p4 36 4 of of IN cord-303046-unksl7p4 36 5 lockdowns lockdown NNS cord-303046-unksl7p4 36 6 and and CC cord-303046-unksl7p4 36 7 suspension suspension NN cord-303046-unksl7p4 36 8 of of IN cord-303046-unksl7p4 36 9 usual usual JJ cord-303046-unksl7p4 36 10 clinical clinical JJ cord-303046-unksl7p4 36 11 care care NN cord-303046-unksl7p4 36 12 activities activity NNS cord-303046-unksl7p4 36 13 for for IN cord-303046-unksl7p4 36 14 the the DT cord-303046-unksl7p4 36 15 benefit benefit NN cord-303046-unksl7p4 36 16 of of IN cord-303046-unksl7p4 36 17 patients patient NNS cord-303046-unksl7p4 36 18 with with IN cord-303046-unksl7p4 36 19 COVID-19 COVID-19 NNP cord-303046-unksl7p4 36 20 , , , cord-303046-unksl7p4 36 21 the the DT cord-303046-unksl7p4 36 22 SARS SARS NNP cord-303046-unksl7p4 36 23 - - HYPH cord-303046-unksl7p4 36 24 CoV-2 CoV-2 NNP cord-303046-unksl7p4 36 25 pandemic pandemic NN cord-303046-unksl7p4 36 26 is be VBZ cord-303046-unksl7p4 36 27 having have VBG cord-303046-unksl7p4 36 28 a a DT cord-303046-unksl7p4 36 29 major major JJ cord-303046-unksl7p4 36 30 effect effect NN cord-303046-unksl7p4 36 31 on on IN cord-303046-unksl7p4 36 32 the the DT cord-303046-unksl7p4 36 33 management management NN cord-303046-unksl7p4 36 34 of of IN cord-303046-unksl7p4 36 35 patients patient NNS cord-303046-unksl7p4 36 36 with with IN cord-303046-unksl7p4 36 37 chronic chronic JJ cord-303046-unksl7p4 36 38 liver liver NN cord-303046-unksl7p4 36 39 diseases disease NNS cord-303046-unksl7p4 36 40 , , , cord-303046-unksl7p4 37 1 in in IN cord-303046-unksl7p4 37 2 particular particular JJ cord-303046-unksl7p4 37 3 those those DT cord-303046-unksl7p4 37 4 with with IN cord-303046-unksl7p4 37 5 cirrhosis cirrhosis NN cord-303046-unksl7p4 37 6 , , , cord-303046-unksl7p4 37 7 hepatocellular hepatocellular JJ cord-303046-unksl7p4 37 8 carcinoma carcinoma NN cord-303046-unksl7p4 37 9 and and CC cord-303046-unksl7p4 37 10 in in IN cord-303046-unksl7p4 37 11 liver liver NN cord-303046-unksl7p4 37 12 transplantation transplantation NN cord-303046-unksl7p4 37 13 programmes programme NNS cord-303046-unksl7p4 37 14 . . . cord-303046-unksl7p4 38 1 The the DT cord-303046-unksl7p4 38 2 feared fear VBN cord-303046-unksl7p4 38 3 risk risk NN cord-303046-unksl7p4 38 4 of of IN cord-303046-unksl7p4 38 5 acquiring acquire VBG cord-303046-unksl7p4 38 6 COVID-19 COVID-19 NNP cord-303046-unksl7p4 38 7 at at IN cord-303046-unksl7p4 38 8 the the DT cord-303046-unksl7p4 38 9 hospital hospital NN cord-303046-unksl7p4 38 10 also also RB cord-303046-unksl7p4 38 11 prevented prevent VBD cord-303046-unksl7p4 38 12 many many JJ cord-303046-unksl7p4 38 13 patients patient NNS cord-303046-unksl7p4 38 14 from from IN cord-303046-unksl7p4 38 15 being be VBG cord-303046-unksl7p4 38 16 appropriately appropriately RB cord-303046-unksl7p4 38 17 managed manage VBN cord-303046-unksl7p4 38 18 by by IN cord-303046-unksl7p4 38 19 hepatology hepatology NN cord-303046-unksl7p4 38 20 teams team NNS cord-303046-unksl7p4 38 21 . . . cord-303046-unksl7p4 39 1 The the DT cord-303046-unksl7p4 39 2 effect effect NN cord-303046-unksl7p4 39 3 of of IN cord-303046-unksl7p4 39 4 the the DT cord-303046-unksl7p4 39 5 pandemic pandemic NN cord-303046-unksl7p4 39 6 on on IN cord-303046-unksl7p4 39 7 care care NN cord-303046-unksl7p4 39 8 of of IN cord-303046-unksl7p4 39 9 patients patient NNS cord-303046-unksl7p4 39 10 with with IN cord-303046-unksl7p4 39 11 cirrhosis cirrhosis NN cord-303046-unksl7p4 39 12 was be VBD cord-303046-unksl7p4 39 13 anti anti JJ cord-303046-unksl7p4 39 14 cipated cipate VBN cord-303046-unksl7p4 39 15 to to TO cord-303046-unksl7p4 39 16 follow follow VB cord-303046-unksl7p4 39 17 three three CD cord-303046-unksl7p4 39 18 waves wave NNS cord-303046-unksl7p4 39 19 : : : cord-303046-unksl7p4 39 20 first first RB cord-303046-unksl7p4 39 21 , , , cord-303046-unksl7p4 39 22 an an DT cord-303046-unksl7p4 39 23 intense intense JJ cord-303046-unksl7p4 39 24 period period NN cord-303046-unksl7p4 39 25 with with IN cord-303046-unksl7p4 39 26 prioritized prioritize VBN cord-303046-unksl7p4 39 27 high high JJ cord-303046-unksl7p4 39 28 - - HYPH cord-303046-unksl7p4 39 29 acuity acuity NN cord-303046-unksl7p4 39 30 care care NN cord-303046-unksl7p4 39 31 with with IN cord-303046-unksl7p4 39 32 delayed delay VBN cord-303046-unksl7p4 39 33 elective elective JJ cord-303046-unksl7p4 39 34 procedures procedure NNS cord-303046-unksl7p4 39 35 and and CC cord-303046-unksl7p4 39 36 routine routine JJ cord-303046-unksl7p4 39 37 care care NN cord-303046-unksl7p4 39 38 during during IN cord-303046-unksl7p4 39 39 physical physical JJ cord-303046-unksl7p4 39 40 distancing distancing NN cord-303046-unksl7p4 39 41 ; ; : cord-303046-unksl7p4 39 42 then then RB cord-303046-unksl7p4 39 43 a a DT cord-303046-unksl7p4 39 44 challenging challenging JJ cord-303046-unksl7p4 39 45 ' ' '' cord-303046-unksl7p4 39 46 return return NN cord-303046-unksl7p4 39 47 to to IN cord-303046-unksl7p4 39 48 normal normal JJ cord-303046-unksl7p4 39 49 ' ' '' cord-303046-unksl7p4 39 50 following follow VBG cord-303046-unksl7p4 39 51 the the DT cord-303046-unksl7p4 39 52 end end NN cord-303046-unksl7p4 39 53 of of IN cord-303046-unksl7p4 39 54 physical physical JJ cord-303046-unksl7p4 39 55 distancing distancing NN cord-303046-unksl7p4 39 56 , , , cord-303046-unksl7p4 39 57 with with IN cord-303046-unksl7p4 39 58 increased increase VBN cord-303046-unksl7p4 39 59 emergent emergent JJ cord-303046-unksl7p4 39 60 decompensations decompensation NNS cord-303046-unksl7p4 39 61 , , , cord-303046-unksl7p4 39 62 morbidity morbidity NN cord-303046-unksl7p4 39 63 and and CC cord-303046-unksl7p4 39 64 systems system NNS cord-303046-unksl7p4 39 65 of of IN cord-303046-unksl7p4 39 66 care care NN cord-303046-unksl7p4 39 67 overwhelmed overwhelmed JJ cord-303046-unksl7p4 39 68 by by IN cord-303046-unksl7p4 39 69 the the DT cord-303046-unksl7p4 39 70 backlog backlog NN cord-303046-unksl7p4 39 71 of of IN cord-303046-unksl7p4 39 72 deferred deferred JJ cord-303046-unksl7p4 39 73 care care NN cord-303046-unksl7p4 39 74 ; ; : cord-303046-unksl7p4 39 75 and and CC cord-303046-unksl7p4 39 76 finally finally RB cord-303046-unksl7p4 39 77 , , , cord-303046-unksl7p4 39 78 a a DT cord-303046-unksl7p4 39 79 protracted protracted JJ cord-303046-unksl7p4 39 80 period period NN cord-303046-unksl7p4 39 81 of of IN cord-303046-unksl7p4 39 82 suboptimal suboptimal JJ cord-303046-unksl7p4 39 83 outcomes outcome NNS cord-303046-unksl7p4 39 84 characterized characterize VBN cord-303046-unksl7p4 39 85 by by IN cord-303046-unksl7p4 39 86 missed miss VBN cord-303046-unksl7p4 39 87 diagnoses diagnosis NNS cord-303046-unksl7p4 39 88 , , , cord-303046-unksl7p4 39 89 progressive progressive JJ cord-303046-unksl7p4 39 90 disease disease NN cord-303046-unksl7p4 39 91 and and CC cord-303046-unksl7p4 39 92 loss loss NN cord-303046-unksl7p4 39 93 to to TO cord-303046-unksl7p4 39 94 follow follow VB cord-303046-unksl7p4 39 95 - - HYPH cord-303046-unksl7p4 39 96 up up NN cord-303046-unksl7p4 39 97 9 9 CD cord-303046-unksl7p4 39 98 . . . cord-303046-unksl7p4 40 1 The the DT cord-303046-unksl7p4 40 2 COVID-19 COVID-19 NNP cord-303046-unksl7p4 40 3 pandemic pandemic NN cord-303046-unksl7p4 40 4 will will MD cord-303046-unksl7p4 40 5 also also RB cord-303046-unksl7p4 40 6 negatively negatively RB cord-303046-unksl7p4 40 7 affect affect VB cord-303046-unksl7p4 40 8 the the DT cord-303046-unksl7p4 40 9 care care NN cord-303046-unksl7p4 40 10 and and CC cord-303046-unksl7p4 40 11 management management NN cord-303046-unksl7p4 40 12 of of IN cord-303046-unksl7p4 40 13 patients patient NNS cord-303046-unksl7p4 40 14 with with IN cord-303046-unksl7p4 40 15 hepatocellular hepatocellular JJ cord-303046-unksl7p4 40 16 carcinoma carcinoma NN cord-303046-unksl7p4 40 17 , , , cord-303046-unksl7p4 40 18 generating generate VBG cord-303046-unksl7p4 40 19 delayed delay VBN cord-303046-unksl7p4 40 20 diagnosis diagnosis NN cord-303046-unksl7p4 40 21 , , , cord-303046-unksl7p4 40 22 deferred defer VBN cord-303046-unksl7p4 40 23 treatment treatment NN cord-303046-unksl7p4 40 24 ( ( -LRB- cord-303046-unksl7p4 40 25 including include VBG cord-303046-unksl7p4 40 26 medical medical JJ cord-303046-unksl7p4 40 27 and and CC cord-303046-unksl7p4 40 28 surgical surgical JJ cord-303046-unksl7p4 40 29 , , , cord-303046-unksl7p4 40 30 such such JJ cord-303046-unksl7p4 40 31 as as IN cord-303046-unksl7p4 40 32 access access NN cord-303046-unksl7p4 40 33 to to IN cord-303046-unksl7p4 40 34 liver liver NN cord-303046-unksl7p4 40 35 transplantation transplantation NN cord-303046-unksl7p4 40 36 ) ) -RRB- cord-303046-unksl7p4 40 37 , , , cord-303046-unksl7p4 40 38 loss loss NN cord-303046-unksl7p4 40 39 to to TO cord-303046-unksl7p4 40 40 follow follow VB cord-303046-unksl7p4 40 41 - - HYPH cord-303046-unksl7p4 40 42 up up NN cord-303046-unksl7p4 40 43 and and CC cord-303046-unksl7p4 40 44 , , , cord-303046-unksl7p4 40 45 ultimately ultimately RB cord-303046-unksl7p4 40 46 , , , cord-303046-unksl7p4 40 47 increased increase VBN cord-303046-unksl7p4 40 48 mortality mortality NN cord-303046-unksl7p4 40 49 . . . cord-303046-unksl7p4 41 1 Liver liver NN cord-303046-unksl7p4 41 2 transplantation transplantation NN cord-303046-unksl7p4 41 3 has have VBZ cord-303046-unksl7p4 41 4 been be VBN cord-303046-unksl7p4 41 5 challenging challenge VBG cord-303046-unksl7p4 41 6 during during IN cord-303046-unksl7p4 41 7 the the DT cord-303046-unksl7p4 41 8 COVID-19 COVID-19 NNP cord-303046-unksl7p4 41 9 pandemic pandemic NN cord-303046-unksl7p4 41 10 , , , cord-303046-unksl7p4 41 11 as as IN cord-303046-unksl7p4 41 12 many many JJ cord-303046-unksl7p4 41 13 centres centre NNS cord-303046-unksl7p4 41 14 had have VBD cord-303046-unksl7p4 41 15 to to TO cord-303046-unksl7p4 41 16 virtually virtually RB cord-303046-unksl7p4 41 17 stop stop VB cord-303046-unksl7p4 41 18 or or CC cord-303046-unksl7p4 41 19 drastically drastically RB cord-303046-unksl7p4 41 20 reduce reduce VB cord-303046-unksl7p4 41 21 their -PRON- PRP$ cord-303046-unksl7p4 41 22 transplantation transplantation NN cord-303046-unksl7p4 41 23 programmes programme NNS cord-303046-unksl7p4 41 24 owing owe VBG cord-303046-unksl7p4 41 25 to to IN cord-303046-unksl7p4 41 26 a a DT cord-303046-unksl7p4 41 27 dramatic dramatic JJ cord-303046-unksl7p4 41 28 reduction reduction NN cord-303046-unksl7p4 41 29 in in IN cord-303046-unksl7p4 41 30 the the DT cord-303046-unksl7p4 41 31 number number NN cord-303046-unksl7p4 41 32 of of IN cord-303046-unksl7p4 41 33 donors donor NNS cord-303046-unksl7p4 41 34 and and CC cord-303046-unksl7p4 41 35 the the DT cord-303046-unksl7p4 41 36 switch switch NN cord-303046-unksl7p4 41 37 of of IN cord-303046-unksl7p4 41 38 many many JJ cord-303046-unksl7p4 41 39 care care NN cord-303046-unksl7p4 41 40 facilities facility NNS cord-303046-unksl7p4 41 41 into into IN cord-303046-unksl7p4 41 42 COVID-19 covid-19 JJ cord-303046-unksl7p4 41 43 units unit NNS cord-303046-unksl7p4 41 44 . . . cord-303046-unksl7p4 42 1 SARS SARS NNP cord-303046-unksl7p4 42 2 - - HYPH cord-303046-unksl7p4 42 3 CoV-2 CoV-2 NNP cord-303046-unksl7p4 42 4 testing testing NN cord-303046-unksl7p4 42 5 in in IN cord-303046-unksl7p4 42 6 donors donor NNS cord-303046-unksl7p4 42 7 and and CC cord-303046-unksl7p4 42 8 recipients recipient NNS cord-303046-unksl7p4 42 9 has have VBZ cord-303046-unksl7p4 42 10 been be VBN cord-303046-unksl7p4 42 11 implemented implement VBN cord-303046-unksl7p4 42 12 in in IN cord-303046-unksl7p4 42 13 many many JJ cord-303046-unksl7p4 42 14 places place NNS cord-303046-unksl7p4 42 15 , , , cord-303046-unksl7p4 42 16 but but CC cord-303046-unksl7p4 42 17 the the DT cord-303046-unksl7p4 42 18 effect effect NN cord-303046-unksl7p4 42 19 of of IN cord-303046-unksl7p4 42 20 COVID-19 COVID-19 NNP cord-303046-unksl7p4 42 21 on on IN cord-303046-unksl7p4 42 22 the the DT cord-303046-unksl7p4 42 23 outcome outcome NN cord-303046-unksl7p4 42 24 of of IN cord-303046-unksl7p4 42 25 liver liver NN cord-303046-unksl7p4 42 26 transplantation transplantation NN cord-303046-unksl7p4 42 27 is be VBZ cord-303046-unksl7p4 42 28 unknown unknown JJ cord-303046-unksl7p4 42 29 . . . cord-303046-unksl7p4 43 1 The the DT cord-303046-unksl7p4 43 2 role role NN cord-303046-unksl7p4 43 3 of of IN cord-303046-unksl7p4 43 4 post post JJ cord-303046-unksl7p4 43 5 - - JJ cord-303046-unksl7p4 43 6 transplantation transplantation JJ cord-303046-unksl7p4 43 7 immune immune JJ cord-303046-unksl7p4 43 8 suppression suppression NN cord-303046-unksl7p4 43 9 on on IN cord-303046-unksl7p4 43 10 the the DT cord-303046-unksl7p4 43 11 course course NN cord-303046-unksl7p4 43 12 of of IN cord-303046-unksl7p4 43 13 COVID-19 COVID-19 NNP cord-303046-unksl7p4 43 14 is be VBZ cord-303046-unksl7p4 43 15 also also RB cord-303046-unksl7p4 43 16 largely largely RB cord-303046-unksl7p4 43 17 unknown unknown JJ cord-303046-unksl7p4 43 18 owing owe VBG cord-303046-unksl7p4 43 19 to to IN cord-303046-unksl7p4 43 20 the the DT cord-303046-unksl7p4 43 21 scarcity scarcity NN cord-303046-unksl7p4 43 22 of of IN cord-303046-unksl7p4 43 23 data datum NNS cord-303046-unksl7p4 43 24 . . . cord-303046-unksl7p4 44 1 Overall overall RB cord-303046-unksl7p4 44 2 , , , cord-303046-unksl7p4 44 3 information information NN cord-303046-unksl7p4 44 4 is be VBZ cord-303046-unksl7p4 44 5 still still RB cord-303046-unksl7p4 44 6 limited limited JJ cord-303046-unksl7p4 44 7 , , , cord-303046-unksl7p4 44 8 but but CC cord-303046-unksl7p4 44 9 it -PRON- PRP cord-303046-unksl7p4 44 10 is be VBZ cord-303046-unksl7p4 44 11 likely likely JJ cord-303046-unksl7p4 44 12 that that IN cord-303046-unksl7p4 44 13 COVID-19 COVID-19 NNP cord-303046-unksl7p4 44 14 will will MD cord-303046-unksl7p4 44 15 result result VB cord-303046-unksl7p4 44 16 in in IN cord-303046-unksl7p4 44 17 a a DT cord-303046-unksl7p4 44 18 substantial substantial JJ cord-303046-unksl7p4 44 19 , , , cord-303046-unksl7p4 44 20 delayed delayed JJ cord-303046-unksl7p4 44 21 increase increase NN cord-303046-unksl7p4 44 22 in in IN cord-303046-unksl7p4 44 23 liver liver NN cord-303046-unksl7p4 44 24 - - HYPH cord-303046-unksl7p4 44 25 related relate VBN cord-303046-unksl7p4 44 26 mortality mortality NN cord-303046-unksl7p4 44 27 that that WDT cord-303046-unksl7p4 44 28 will will MD cord-303046-unksl7p4 44 29 become become VB cord-303046-unksl7p4 44 30 visible visible JJ cord-303046-unksl7p4 44 31 in in IN cord-303046-unksl7p4 44 32 the the DT cord-303046-unksl7p4 44 33 coming come VBG cord-303046-unksl7p4 44 34 months month NNS cord-303046-unksl7p4 44 35 and and CC cord-303046-unksl7p4 44 36 will will MD cord-303046-unksl7p4 44 37 substantially substantially RB cord-303046-unksl7p4 44 38 contribute contribute VB cord-303046-unksl7p4 44 39 to to IN cord-303046-unksl7p4 44 40 the the DT cord-303046-unksl7p4 44 41 overall overall JJ cord-303046-unksl7p4 44 42 pandemic pandemic NN cord-303046-unksl7p4 44 43 - - HYPH cord-303046-unksl7p4 44 44 related relate VBN cord-303046-unksl7p4 44 45 mortality mortality NN cord-303046-unksl7p4 44 46 . . . cord-303046-unksl7p4 45 1 The the DT cord-303046-unksl7p4 45 2 COVID-19 COVID-19 NNP cord-303046-unksl7p4 45 3 pandemic pandemic NN cord-303046-unksl7p4 45 4 will will MD cord-303046-unksl7p4 45 5 also also RB cord-303046-unksl7p4 45 6 negatively negatively RB cord-303046-unksl7p4 45 7 affect affect VB cord-303046-unksl7p4 45 8 viral viral JJ cord-303046-unksl7p4 45 9 hepatitis hepatitis NN cord-303046-unksl7p4 45 10 elimination elimination NN cord-303046-unksl7p4 45 11 programmes programme NNS cord-303046-unksl7p4 45 12 . . . cord-303046-unksl7p4 46 1 The the DT cord-303046-unksl7p4 46 2 World World NNP cord-303046-unksl7p4 46 3 Health Health NNP cord-303046-unksl7p4 46 4 Organization Organization NNP cord-303046-unksl7p4 46 5 has have VBZ cord-303046-unksl7p4 46 6 set set VBN cord-303046-unksl7p4 46 7 the the DT cord-303046-unksl7p4 46 8 goal goal NN cord-303046-unksl7p4 46 9 of of IN cord-303046-unksl7p4 46 10 eliminating eliminate VBG cord-303046-unksl7p4 46 11 viral viral JJ cord-303046-unksl7p4 46 12 hepatitis hepatitis NN cord-303046-unksl7p4 46 13 B B NNP cord-303046-unksl7p4 46 14 and and CC cord-303046-unksl7p4 46 15 C C NNP cord-303046-unksl7p4 46 16 as as IN cord-303046-unksl7p4 46 17 major major JJ cord-303046-unksl7p4 46 18 public public JJ cord-303046-unksl7p4 46 19 health health NN cord-303046-unksl7p4 46 20 threats threat NNS cord-303046-unksl7p4 46 21 by by IN cord-303046-unksl7p4 46 22 2030 2030 CD cord-303046-unksl7p4 46 23 . . . cord-303046-unksl7p4 47 1 This this DT cord-303046-unksl7p4 47 2 aim aim NN cord-303046-unksl7p4 47 3 includes include VBZ cord-303046-unksl7p4 47 4 reducing reduce VBG cord-303046-unksl7p4 47 5 their -PRON- PRP$ cord-303046-unksl7p4 47 6 incidence incidence NN cord-303046-unksl7p4 47 7 , , , cord-303046-unksl7p4 47 8 prevalence prevalence NN cord-303046-unksl7p4 47 9 , , , cord-303046-unksl7p4 47 10 morbidity morbidity NN cord-303046-unksl7p4 47 11 and and CC cord-303046-unksl7p4 47 12 mortality mortality NN cord-303046-unksl7p4 47 13 by by IN cord-303046-unksl7p4 47 14 means mean NNS cord-303046-unksl7p4 47 15 of of IN cord-303046-unksl7p4 47 16 prevention prevention NN cord-303046-unksl7p4 47 17 measures measure NNS cord-303046-unksl7p4 47 18 , , , cord-303046-unksl7p4 47 19 including include VBG cord-303046-unksl7p4 47 20 hepatitis hepatitis NNP cord-303046-unksl7p4 47 21 B B NNP cord-303046-unksl7p4 47 22 vaccination vaccination NN cord-303046-unksl7p4 47 23 , , , cord-303046-unksl7p4 47 24 extensive extensive JJ cord-303046-unksl7p4 47 25 screening screening NN cord-303046-unksl7p4 47 26 and and CC cord-303046-unksl7p4 47 27 improved improved JJ cord-303046-unksl7p4 47 28 access access NN cord-303046-unksl7p4 47 29 to to IN cord-303046-unksl7p4 47 30 care care NN cord-303046-unksl7p4 47 31 and and CC cord-303046-unksl7p4 47 32 antiviral antiviral JJ cord-303046-unksl7p4 47 33 treatments treatment NNS cord-303046-unksl7p4 47 34 . . . cord-303046-unksl7p4 48 1 During during IN cord-303046-unksl7p4 48 2 the the DT cord-303046-unksl7p4 48 3 COVID-19 COVID-19 NNP cord-303046-unksl7p4 48 4 crisis crisis NN cord-303046-unksl7p4 48 5 , , , cord-303046-unksl7p4 48 6 attention attention NN cord-303046-unksl7p4 48 7 has have VBZ cord-303046-unksl7p4 48 8 been be VBN cord-303046-unksl7p4 48 9 diverted divert VBN cord-303046-unksl7p4 48 10 from from IN cord-303046-unksl7p4 48 11 chronic chronic JJ cord-303046-unksl7p4 48 12 viral viral JJ cord-303046-unksl7p4 48 13 hepa hepa NNP cord-303046-unksl7p4 48 14 titis titis NNP cord-303046-unksl7p4 48 15 , , , cord-303046-unksl7p4 48 16 despite despite IN cord-303046-unksl7p4 48 17 the the DT cord-303046-unksl7p4 48 18 fact fact NN cord-303046-unksl7p4 48 19 that that IN cord-303046-unksl7p4 48 20 global global JJ cord-303046-unksl7p4 48 21 mortality mortality NN cord-303046-unksl7p4 48 22 attributed attribute VBN cord-303046-unksl7p4 48 23 to to IN cord-303046-unksl7p4 48 24 viral viral JJ cord-303046-unksl7p4 48 25 hepatitis hepatitis NN cord-303046-unksl7p4 48 26 , , , cord-303046-unksl7p4 48 27 which which WDT cord-303046-unksl7p4 48 28 has have VBZ cord-303046-unksl7p4 48 29 been be VBN cord-303046-unksl7p4 48 30 estimated estimate VBN cord-303046-unksl7p4 48 31 by by IN cord-303046-unksl7p4 48 32 the the DT cord-303046-unksl7p4 48 33 WHO WHO NNP cord-303046-unksl7p4 48 34 Global Global NNP cord-303046-unksl7p4 48 35 Hepatitis Hepatitis NNP cord-303046-unksl7p4 48 36 Report Report NNP cord-303046-unksl7p4 48 37 2017 2017 CD cord-303046-unksl7p4 48 38 to to TO cord-303046-unksl7p4 48 39 be be VB cord-303046-unksl7p4 48 40 approximately approximately RB cord-303046-unksl7p4 48 41 1.5 1.5 CD cord-303046-unksl7p4 48 42 million million CD cord-303046-unksl7p4 48 43 per per IN cord-303046-unksl7p4 48 44 year year NN cord-303046-unksl7p4 48 45 , , , cord-303046-unksl7p4 48 46 currently currently RB cord-303046-unksl7p4 48 47 remains remain VBZ cord-303046-unksl7p4 48 48 higher high JJR cord-303046-unksl7p4 48 49 than than IN cord-303046-unksl7p4 48 50 that that DT cord-303046-unksl7p4 48 51 from from IN cord-303046-unksl7p4 48 52 COVID-19 COVID-19 NNP cord-303046-unksl7p4 48 53 , , , cord-303046-unksl7p4 48 54 while while IN cord-303046-unksl7p4 48 55 resources resource NNS cord-303046-unksl7p4 48 56 for for IN cord-303046-unksl7p4 48 57 public public JJ cord-303046-unksl7p4 48 58 health health NN cord-303046-unksl7p4 48 59 interventions intervention NNS cord-303046-unksl7p4 48 60 are be VBP cord-303046-unksl7p4 48 61 already already RB cord-303046-unksl7p4 48 62 shrinking shrink VBG cord-303046-unksl7p4 48 63 . . . cord-303046-unksl7p4 49 1 Lockdown lockdown NN cord-303046-unksl7p4 49 2 , , , cord-303046-unksl7p4 49 3 quarantine quarantine NN cord-303046-unksl7p4 49 4 and and CC cord-303046-unksl7p4 49 5 social social JJ cord-303046-unksl7p4 49 6 distancing distancing NN cord-303046-unksl7p4 49 7 , , , cord-303046-unksl7p4 49 8 closing close VBG cord-303046-unksl7p4 49 9 of of IN cord-303046-unksl7p4 49 10 harm harm NN cord-303046-unksl7p4 49 11 reduction reduction NN cord-303046-unksl7p4 49 12 and and CC cord-303046-unksl7p4 49 13 treatment treatment NN cord-303046-unksl7p4 49 14 facilities facility NNS cord-303046-unksl7p4 49 15 , , , cord-303046-unksl7p4 49 16 including include VBG cord-303046-unksl7p4 49 17 primary primary JJ cord-303046-unksl7p4 49 18 care care NN cord-303046-unksl7p4 49 19 settings setting NNS cord-303046-unksl7p4 49 20 and and CC cord-303046-unksl7p4 49 21 general general JJ cord-303046-unksl7p4 49 22 practitioners practitioner NNS cord-303046-unksl7p4 49 23 , , , cord-303046-unksl7p4 49 24 will will MD cord-303046-unksl7p4 49 25 probably probably RB cord-303046-unksl7p4 49 26 hamper hamper VB cord-303046-unksl7p4 49 27 the the DT cord-303046-unksl7p4 49 28 major major JJ cord-303046-unksl7p4 49 29 efforts effort NNS cord-303046-unksl7p4 49 30 made make VBN cord-303046-unksl7p4 49 31 to to TO cord-303046-unksl7p4 49 32 achieve achieve VB cord-303046-unksl7p4 49 33 the the DT cord-303046-unksl7p4 49 34 viral viral JJ cord-303046-unksl7p4 49 35 hepatitis hepatitis NN cord-303046-unksl7p4 49 36 elimination elimination NN cord-303046-unksl7p4 49 37 goals goal NNS cord-303046-unksl7p4 49 38 in in IN cord-303046-unksl7p4 49 39 many many JJ cord-303046-unksl7p4 49 40 areas area NNS cord-303046-unksl7p4 49 41 , , , cord-303046-unksl7p4 49 42 further further RB cord-303046-unksl7p4 49 43 increasing increase VBG cord-303046-unksl7p4 49 44 indirect indirect JJ cord-303046-unksl7p4 49 45 COVID-19-linked COVID-19-linked NNP cord-303046-unksl7p4 49 46 mortality mortality NN cord-303046-unksl7p4 49 47 10 10 CD cord-303046-unksl7p4 49 48 . . . cord-303046-unksl7p4 50 1 The the DT cord-303046-unksl7p4 50 2 greatest great JJS cord-303046-unksl7p4 50 3 effect effect NN cord-303046-unksl7p4 50 4 of of IN cord-303046-unksl7p4 50 5 COVID-19 COVID-19 NNP cord-303046-unksl7p4 50 6 on on IN cord-303046-unksl7p4 50 7 liver liver NN cord-303046-unksl7p4 50 8 - - HYPH cord-303046-unksl7p4 50 9 related relate VBN cord-303046-unksl7p4 50 10 morbidity morbidity NN cord-303046-unksl7p4 50 11 and and CC cord-303046-unksl7p4 50 12 mortality mortality NN cord-303046-unksl7p4 50 13 remains remain VBZ cord-303046-unksl7p4 50 14 to to TO cord-303046-unksl7p4 50 15 come come VB cord-303046-unksl7p4 50 16 , , , cord-303046-unksl7p4 50 17 as as IN cord-303046-unksl7p4 50 18 a a DT cord-303046-unksl7p4 50 19 result result NN cord-303046-unksl7p4 50 20 of of IN cord-303046-unksl7p4 50 21 the the DT cord-303046-unksl7p4 50 22 global global JJ cord-303046-unksl7p4 50 23 economic economic JJ cord-303046-unksl7p4 50 24 crisis crisis NN cord-303046-unksl7p4 50 25 that that WDT cord-303046-unksl7p4 50 26 has have VBZ cord-303046-unksl7p4 50 27 already already RB cord-303046-unksl7p4 50 28 begun begin VBN cord-303046-unksl7p4 50 29 . . . cord-303046-unksl7p4 51 1 Bankruptcies bankruptcy NNS cord-303046-unksl7p4 51 2 , , , cord-303046-unksl7p4 51 3 job job NN cord-303046-unksl7p4 51 4 losses loss NNS cord-303046-unksl7p4 51 5 , , , cord-303046-unksl7p4 51 6 money money NN cord-303046-unksl7p4 51 7 and and CC cord-303046-unksl7p4 51 8 food food NN cord-303046-unksl7p4 51 9 shortage shortage NN cord-303046-unksl7p4 51 10 , , , cord-303046-unksl7p4 51 11 social social JJ cord-303046-unksl7p4 51 12 isolation isolation NN cord-303046-unksl7p4 51 13 and and CC cord-303046-unksl7p4 51 14 family family NN cord-303046-unksl7p4 51 15 issues issue NNS cord-303046-unksl7p4 51 16 will will MD cord-303046-unksl7p4 51 17 lead lead VB cord-303046-unksl7p4 51 18 to to IN cord-303046-unksl7p4 51 19 increases increase NNS cord-303046-unksl7p4 51 20 in in IN cord-303046-unksl7p4 51 21 alcohol alcohol NN cord-303046-unksl7p4 51 22 and and CC cord-303046-unksl7p4 51 23 drug drug NN cord-303046-unksl7p4 51 24 use use NN cord-303046-unksl7p4 51 25 , , , cord-303046-unksl7p4 51 26 whereas whereas IN cord-303046-unksl7p4 51 27 access access NN cord-303046-unksl7p4 51 28 to to IN cord-303046-unksl7p4 51 29 care care NN cord-303046-unksl7p4 51 30 will will MD cord-303046-unksl7p4 51 31 suffer suffer VB cord-303046-unksl7p4 51 32 from from IN cord-303046-unksl7p4 51 33 the the DT cord-303046-unksl7p4 51 34 collapse collapse NN cord-303046-unksl7p4 51 35 of of IN cord-303046-unksl7p4 51 36 health health NN cord-303046-unksl7p4 51 37 - - HYPH cord-303046-unksl7p4 51 38 care care NN cord-303046-unksl7p4 51 39 structures structure NNS cord-303046-unksl7p4 51 40 and and CC cord-303046-unksl7p4 51 41 organizations organization NNS cord-303046-unksl7p4 51 42 , , , cord-303046-unksl7p4 51 43 and and CC cord-303046-unksl7p4 51 44 from from IN cord-303046-unksl7p4 51 45 government government NN cord-303046-unksl7p4 51 46 policies policy NNS cord-303046-unksl7p4 51 47 diverting divert VBG cord-303046-unksl7p4 51 48 resources resource NNS cord-303046-unksl7p4 51 49 elsewhere elsewhere RB cord-303046-unksl7p4 51 50 . . . cord-303046-unksl7p4 52 1 This this DT cord-303046-unksl7p4 52 2 situation situation NN cord-303046-unksl7p4 52 3 could could MD cord-303046-unksl7p4 52 4 translate translate VB cord-303046-unksl7p4 52 5 into into IN cord-303046-unksl7p4 52 6 a a DT cord-303046-unksl7p4 52 7 substantial substantial JJ cord-303046-unksl7p4 52 8 increase increase NN cord-303046-unksl7p4 52 9 in in IN cord-303046-unksl7p4 52 10 blood blood NN cord-303046-unksl7p4 52 11 - - HYPH cord-303046-unksl7p4 52 12 borne bear VBN cord-303046-unksl7p4 52 13 virus virus NN cord-303046-unksl7p4 52 14 transmissions transmission NNS cord-303046-unksl7p4 52 15 ( ( -LRB- cord-303046-unksl7p4 52 16 in in IN cord-303046-unksl7p4 52 17 addition addition NN cord-303046-unksl7p4 52 18 to to IN cord-303046-unksl7p4 52 19 the the DT cord-303046-unksl7p4 52 20 current current JJ cord-303046-unksl7p4 52 21 opioid opioid JJ cord-303046-unksl7p4 52 22 epidemic epidemic NN cord-303046-unksl7p4 52 23 in in IN cord-303046-unksl7p4 52 24 North North NNP cord-303046-unksl7p4 52 25 America America NNP cord-303046-unksl7p4 52 26 , , , cord-303046-unksl7p4 52 27 which which WDT cord-303046-unksl7p4 52 28 is be VBZ cord-303046-unksl7p4 52 29 already already RB cord-303046-unksl7p4 52 30 rapidly rapidly RB cord-303046-unksl7p4 52 31 increasing increase VBG cord-303046-unksl7p4 52 32 the the DT cord-303046-unksl7p4 52 33 incidence incidence NN cord-303046-unksl7p4 52 34 of of IN cord-303046-unksl7p4 52 35 new new JJ cord-303046-unksl7p4 52 36 hepatitis hepatitis NN cord-303046-unksl7p4 52 37 C C NNP cord-303046-unksl7p4 52 38 cases case NNS cord-303046-unksl7p4 52 39 ) ) -RRB- cord-303046-unksl7p4 52 40 , , , cord-303046-unksl7p4 52 41 as as RB cord-303046-unksl7p4 52 42 well well RB cord-303046-unksl7p4 52 43 as as IN cord-303046-unksl7p4 52 44 in in IN cord-303046-unksl7p4 52 45 alcoholic alcoholic JJ cord-303046-unksl7p4 52 46 liver liver NN cord-303046-unksl7p4 52 47 disorders disorder NNS cord-303046-unksl7p4 52 48 and and CC cord-303046-unksl7p4 52 49 decompensations decompensation NNS cord-303046-unksl7p4 52 50 , , , cord-303046-unksl7p4 52 51 resulting result VBG cord-303046-unksl7p4 52 52 in in IN cord-303046-unksl7p4 52 53 many many JJ cord-303046-unksl7p4 52 54 more more JJR cord-303046-unksl7p4 52 55 patients patient NNS cord-303046-unksl7p4 52 56 with with IN cord-303046-unksl7p4 52 57 cirrhosis cirrhosis NN cord-303046-unksl7p4 52 58 , , , cord-303046-unksl7p4 52 59 hepatocellular hepatocellular JJ cord-303046-unksl7p4 52 60 carcinoma carcinoma NN cord-303046-unksl7p4 52 61 , , , cord-303046-unksl7p4 52 62 liver liver NN cord-303046-unksl7p4 52 63 transplantation transplantation NN cord-303046-unksl7p4 52 64 and and CC cord-303046-unksl7p4 52 65 liver liver NN cord-303046-unksl7p4 52 66 - - HYPH cord-303046-unksl7p4 52 67 related relate VBN cord-303046-unksl7p4 52 68 death death NN cord-303046-unksl7p4 52 69 . . . cord-303046-unksl7p4 53 1 These these DT cord-303046-unksl7p4 53 2 unforeseen unforeseen JJ cord-303046-unksl7p4 53 3 effects effect NNS cord-303046-unksl7p4 53 4 of of IN cord-303046-unksl7p4 53 5 the the DT cord-303046-unksl7p4 53 6 COVID-19 COVID-19 NNP cord-303046-unksl7p4 53 7 pandemic pandemic NN cord-303046-unksl7p4 53 8 will will MD cord-303046-unksl7p4 53 9 take take VB cord-303046-unksl7p4 53 10 years year NNS cord-303046-unksl7p4 53 11 to to TO cord-303046-unksl7p4 53 12 become become VB cord-303046-unksl7p4 53 13 visible visible JJ cord-303046-unksl7p4 53 14 , , , cord-303046-unksl7p4 53 15 but but CC cord-303046-unksl7p4 53 16 they -PRON- PRP cord-303046-unksl7p4 53 17 are be VBP cord-303046-unksl7p4 53 18 inevitable inevitable JJ cord-303046-unksl7p4 53 19 . . . cord-303046-unksl7p4 54 1 In in IN cord-303046-unksl7p4 54 2 summary summary NN cord-303046-unksl7p4 54 3 ( ( -LRB- cord-303046-unksl7p4 54 4 Box Box NNP cord-303046-unksl7p4 54 5 1 1 CD cord-303046-unksl7p4 54 6 ) ) -RRB- cord-303046-unksl7p4 54 7 , , , cord-303046-unksl7p4 54 8 SARS SARS NNP cord-303046-unksl7p4 54 9 - - HYPH cord-303046-unksl7p4 54 10 CoV-2 CoV-2 NNP cord-303046-unksl7p4 54 11 infection infection NN cord-303046-unksl7p4 54 12 appears appear VBZ cord-303046-unksl7p4 54 13 to to TO cord-303046-unksl7p4 54 14 relatively relatively RB cord-303046-unksl7p4 54 15 spare spare VB cord-303046-unksl7p4 54 16 the the DT cord-303046-unksl7p4 54 17 liver liver NN cord-303046-unksl7p4 54 18 , , , cord-303046-unksl7p4 54 19 with with IN cord-303046-unksl7p4 54 20 negligible negligible JJ cord-303046-unksl7p4 54 21 liver liver NN cord-303046-unksl7p4 54 22 - - HYPH cord-303046-unksl7p4 54 23 related relate VBN cord-303046-unksl7p4 54 24 mortality mortality NN cord-303046-unksl7p4 54 25 during during IN cord-303046-unksl7p4 54 26 the the DT cord-303046-unksl7p4 54 27 course course NN cord-303046-unksl7p4 54 28 of of IN cord-303046-unksl7p4 54 29 COVID-19 COVID-19 NNP cord-303046-unksl7p4 54 30 ( ( -LRB- cord-303046-unksl7p4 54 31 with with IN cord-303046-unksl7p4 54 32 the the DT cord-303046-unksl7p4 54 33 exceptions exception NNS cord-303046-unksl7p4 54 34 of of IN cord-303046-unksl7p4 54 35 liver liver NN cord-303046-unksl7p4 54 36 failure failure NN cord-303046-unksl7p4 54 37 in in IN cord-303046-unksl7p4 54 38 patients patient NNS cord-303046-unksl7p4 54 39 with with IN cord-303046-unksl7p4 54 40 very very RB cord-303046-unksl7p4 54 41 severe severe JJ cord-303046-unksl7p4 54 42 COVID-19 covid-19 JJ cord-303046-unksl7p4 54 43 infection infection NN cord-303046-unksl7p4 54 44 leading lead VBG cord-303046-unksl7p4 54 45 to to IN cord-303046-unksl7p4 54 46 multivisceral multivisceral JJ cord-303046-unksl7p4 54 47 deficiencies deficiency NNS cord-303046-unksl7p4 54 48 and and CC cord-303046-unksl7p4 54 49 of of IN cord-303046-unksl7p4 54 50 patients patient NNS cord-303046-unksl7p4 54 51 with with IN cord-303046-unksl7p4 54 52 decompensated decompensated JJ cord-303046-unksl7p4 54 53 cirrhosis cirrhosis NN cord-303046-unksl7p4 54 54 ) ) -RRB- cord-303046-unksl7p4 54 55 . . . cord-303046-unksl7p4 55 1 Nevertheless nevertheless RB cord-303046-unksl7p4 55 2 , , , cord-303046-unksl7p4 55 3 the the DT cord-303046-unksl7p4 55 4 effect effect NN cord-303046-unksl7p4 55 5 of of IN cord-303046-unksl7p4 55 6 the the DT cord-303046-unksl7p4 55 7 COVID-19 covid-19 JJ cord-303046-unksl7p4 55 8 pandemic pandemic NN cord-303046-unksl7p4 55 9 on on IN cord-303046-unksl7p4 55 10 liver liver NN cord-303046-unksl7p4 55 11 - - HYPH cord-303046-unksl7p4 55 12 related relate VBN cord-303046-unksl7p4 55 13 mortality mortality NN cord-303046-unksl7p4 55 14 could could MD cord-303046-unksl7p4 55 15 be be VB cord-303046-unksl7p4 55 16 enormous enormous JJ cord-303046-unksl7p4 55 17 , , , cord-303046-unksl7p4 55 18 though though IN cord-303046-unksl7p4 55 19 hidden hide VBN cord-303046-unksl7p4 55 20 , , , cord-303046-unksl7p4 55 21 delayed delay VBN cord-303046-unksl7p4 55 22 and and CC cord-303046-unksl7p4 55 23 not not RB cord-303046-unksl7p4 55 24 ascribed ascribe VBN cord-303046-unksl7p4 55 25 . . . cord-303046-unksl7p4 56 1 Similar similar JJ cord-303046-unksl7p4 56 2 conclusions conclusion NNS cord-303046-unksl7p4 56 3 apply apply VBP cord-303046-unksl7p4 56 4 to to IN cord-303046-unksl7p4 56 5 many many JJ cord-303046-unksl7p4 56 6 other other JJ cord-303046-unksl7p4 56 7 medical medical JJ cord-303046-unksl7p4 56 8 specialties specialty NNS cord-303046-unksl7p4 56 9 and and CC cord-303046-unksl7p4 56 10 should should MD cord-303046-unksl7p4 56 11 be be VB cord-303046-unksl7p4 56 12 considered consider VBN cord-303046-unksl7p4 56 13 when when WRB cord-303046-unksl7p4 56 14 drawing draw VBG cord-303046-unksl7p4 56 15 up up RP cord-303046-unksl7p4 56 16 a a DT cord-303046-unksl7p4 56 17 final final JJ cord-303046-unksl7p4 56 18 assessment assessment NN cord-303046-unksl7p4 56 19 of of IN cord-303046-unksl7p4 56 20 the the DT cord-303046-unksl7p4 56 21 COVID-19 COVID-19 NNP cord-303046-unksl7p4 56 22 pandemic pandemic NN cord-303046-unksl7p4 56 23 , , , cord-303046-unksl7p4 56 24 the the DT cord-303046-unksl7p4 56 25 policies policy NNS cord-303046-unksl7p4 56 26 put put VBN cord-303046-unksl7p4 56 27 in in IN cord-303046-unksl7p4 56 28 place place NN cord-303046-unksl7p4 56 29 to to TO cord-303046-unksl7p4 56 30 combat combat VB cord-303046-unksl7p4 56 31 it -PRON- PRP cord-303046-unksl7p4 56 32 and and CC cord-303046-unksl7p4 56 33 the the DT cord-303046-unksl7p4 56 34 lessons lesson NNS cord-303046-unksl7p4 56 35 to to TO cord-303046-unksl7p4 56 36 be be VB cord-303046-unksl7p4 56 37 learnt learn VBN cord-303046-unksl7p4 56 38 for for IN cord-303046-unksl7p4 56 39 the the DT cord-303046-unksl7p4 56 40 next next JJ cord-303046-unksl7p4 56 41 pandemic pandemic NN cord-303046-unksl7p4 56 42 . . . cord-303046-unksl7p4 57 1 Coronavirus Coronavirus NNP cord-303046-unksl7p4 57 2 disease disease NN cord-303046-unksl7p4 57 3 2019 2019 CD cord-303046-unksl7p4 57 4 ( ( -LRB- cord-303046-unksl7p4 57 5 COviD-19 COviD-19 NNP cord-303046-unksl7p4 57 6 ) ) -RRB- cord-303046-unksl7p4 57 7 has have VBZ cord-303046-unksl7p4 57 8 a a DT cord-303046-unksl7p4 57 9 modest modest JJ cord-303046-unksl7p4 57 10 effect effect NN cord-303046-unksl7p4 57 11 on on IN cord-303046-unksl7p4 57 12 the the DT cord-303046-unksl7p4 57 13 liver liver NN cord-303046-unksl7p4 57 14 , , , cord-303046-unksl7p4 57 15 and and CC cord-303046-unksl7p4 57 16 liver liver NN cord-303046-unksl7p4 57 17 - - HYPH cord-303046-unksl7p4 57 18 related relate VBN cord-303046-unksl7p4 57 19 mortality mortality NN cord-303046-unksl7p4 57 20 is be VBZ cord-303046-unksl7p4 57 21 unusual unusual JJ cord-303046-unksl7p4 57 22 during during IN cord-303046-unksl7p4 57 23 the the DT cord-303046-unksl7p4 57 24 course course NN cord-303046-unksl7p4 57 25 of of IN cord-303046-unksl7p4 57 26 the the DT cord-303046-unksl7p4 57 27 disease disease NN cord-303046-unksl7p4 57 28 , , , cord-303046-unksl7p4 57 29 except except IN cord-303046-unksl7p4 57 30 in in IN cord-303046-unksl7p4 57 31 patients patient NNS cord-303046-unksl7p4 57 32 with with IN cord-303046-unksl7p4 57 33 severe severe JJ cord-303046-unksl7p4 57 34 pulmonary pulmonary JJ cord-303046-unksl7p4 57 35 disease disease NN cord-303046-unksl7p4 57 36 who who WP cord-303046-unksl7p4 57 37 die die VBP cord-303046-unksl7p4 57 38 from from IN cord-303046-unksl7p4 57 39 multivisceral multivisceral JJ cord-303046-unksl7p4 57 40 deficiencies deficiency NNS cord-303046-unksl7p4 57 41 including include VBG cord-303046-unksl7p4 57 42 the the DT cord-303046-unksl7p4 57 43 liver liver NN cord-303046-unksl7p4 57 44 or or CC cord-303046-unksl7p4 57 45 in in IN cord-303046-unksl7p4 57 46 patients patient NNS cord-303046-unksl7p4 57 47 with with IN cord-303046-unksl7p4 57 48 pre pre JJ cord-303046-unksl7p4 57 49 - - JJ cord-303046-unksl7p4 57 50 existing existing JJ cord-303046-unksl7p4 57 51 advanced advanced JJ cord-303046-unksl7p4 57 52 liver liver NN cord-303046-unksl7p4 57 53 disease disease NN cord-303046-unksl7p4 57 54 . . . cord-303046-unksl7p4 58 1 Most most RBS cord-303046-unksl7p4 58 2 COviD-19-induced covid-19-induce VBN cord-303046-unksl7p4 58 3 liver liver NN cord-303046-unksl7p4 58 4 - - HYPH cord-303046-unksl7p4 58 5 mortality mortality NN cord-303046-unksl7p4 58 6 will will MD cord-303046-unksl7p4 58 7 be be VB cord-303046-unksl7p4 58 8 delayed delay VBN cord-303046-unksl7p4 58 9 , , , cord-303046-unksl7p4 58 10 resulting result VBG cord-303046-unksl7p4 58 11 from from IN cord-303046-unksl7p4 58 12 deferred deferred JJ cord-303046-unksl7p4 58 13 care care NN cord-303046-unksl7p4 58 14 for for IN cord-303046-unksl7p4 58 15 liver liver NN cord-303046-unksl7p4 58 16 diseases disease NNS cord-303046-unksl7p4 58 17 , , , cord-303046-unksl7p4 58 18 reduced reduce VBN cord-303046-unksl7p4 58 19 funding funding NN cord-303046-unksl7p4 58 20 for for IN cord-303046-unksl7p4 58 21 public public JJ cord-303046-unksl7p4 58 22 health health NN cord-303046-unksl7p4 58 23 interventions intervention NNS cord-303046-unksl7p4 58 24 and and CC cord-303046-unksl7p4 58 25 the the DT cord-303046-unksl7p4 58 26 global global JJ cord-303046-unksl7p4 58 27 economic economic JJ cord-303046-unksl7p4 58 28 crisis crisis NN cord-303046-unksl7p4 58 29 , , , cord-303046-unksl7p4 58 30 which which WDT cord-303046-unksl7p4 58 31 will will MD cord-303046-unksl7p4 58 32 lead lead VB cord-303046-unksl7p4 58 33 to to IN cord-303046-unksl7p4 58 34 increases increase NNS cord-303046-unksl7p4 58 35 in in IN cord-303046-unksl7p4 58 36 alcohol alcohol NN cord-303046-unksl7p4 58 37 and and CC cord-303046-unksl7p4 58 38 drug drug NN cord-303046-unksl7p4 58 39 use use NN cord-303046-unksl7p4 58 40 and and CC cord-303046-unksl7p4 58 41 in in IN cord-303046-unksl7p4 58 42 blood blood NN cord-303046-unksl7p4 58 43 - - HYPH cord-303046-unksl7p4 58 44 borne bear VBN cord-303046-unksl7p4 58 45 virus virus NN cord-303046-unksl7p4 58 46 transmissions transmission NNS cord-303046-unksl7p4 58 47 , , , cord-303046-unksl7p4 58 48 while while IN cord-303046-unksl7p4 58 49 access access NN cord-303046-unksl7p4 58 50 to to IN cord-303046-unksl7p4 58 51 care care NN cord-303046-unksl7p4 58 52 and and CC cord-303046-unksl7p4 58 53 funding funding NN cord-303046-unksl7p4 58 54 are be VBP cord-303046-unksl7p4 58 55 reduced reduce VBN cord-303046-unksl7p4 58 56 . . . cord-303046-unksl7p4 59 1 Prevention prevention NN cord-303046-unksl7p4 59 2 of of IN cord-303046-unksl7p4 59 3 liver liver NN cord-303046-unksl7p4 59 4 - - HYPH cord-303046-unksl7p4 59 5 related relate VBN cord-303046-unksl7p4 59 6 mortality mortality NN cord-303046-unksl7p4 59 7 following follow VBG cord-303046-unksl7p4 59 8 the the DT cord-303046-unksl7p4 59 9 COviD-19 COviD-19 NNP cord-303046-unksl7p4 59 10 epidemic epidemic NN cord-303046-unksl7p4 59 11 will will MD cord-303046-unksl7p4 59 12 require require VB cord-303046-unksl7p4 59 13 rapid rapid JJ cord-303046-unksl7p4 59 14 resumption resumption NN cord-303046-unksl7p4 59 15 of of IN cord-303046-unksl7p4 59 16 care care NN cord-303046-unksl7p4 59 17 activities activity NNS cord-303046-unksl7p4 59 18 , , , cord-303046-unksl7p4 59 19 in in IN cord-303046-unksl7p4 59 20 particular particular JJ cord-303046-unksl7p4 59 21 for for IN cord-303046-unksl7p4 59 22 patients patient NNS cord-303046-unksl7p4 59 23 with with IN cord-303046-unksl7p4 59 24 advanced advanced JJ cord-303046-unksl7p4 59 25 cirrhosis cirrhosis NN cord-303046-unksl7p4 59 26 or or CC cord-303046-unksl7p4 59 27 hepatocellular hepatocellular JJ cord-303046-unksl7p4 59 28 carcinoma carcinoma NN cord-303046-unksl7p4 59 29 and and CC cord-303046-unksl7p4 59 30 for for IN cord-303046-unksl7p4 59 31 those those DT cord-303046-unksl7p4 59 32 requiring require VBG cord-303046-unksl7p4 59 33 liver liver NN cord-303046-unksl7p4 59 34 transplantation transplantation NN cord-303046-unksl7p4 59 35 , , , cord-303046-unksl7p4 59 36 a a DT cord-303046-unksl7p4 59 37 massive massive JJ cord-303046-unksl7p4 59 38 investment investment NN cord-303046-unksl7p4 59 39 in in IN cord-303046-unksl7p4 59 40 viral viral JJ cord-303046-unksl7p4 59 41 hepatitis hepatitis NN cord-303046-unksl7p4 59 42 elimination elimination NN cord-303046-unksl7p4 59 43 efforts effort NNS cord-303046-unksl7p4 59 44 and and CC cord-303046-unksl7p4 59 45 courageous courageous JJ cord-303046-unksl7p4 59 46 economic economic JJ cord-303046-unksl7p4 59 47 and and CC cord-303046-unksl7p4 59 48 social social JJ cord-303046-unksl7p4 59 49 measures measure NNS cord-303046-unksl7p4 59 50 to to TO cord-303046-unksl7p4 59 51 mitigate mitigate VB cord-303046-unksl7p4 59 52 the the DT cord-303046-unksl7p4 59 53 health health NN cord-303046-unksl7p4 59 54 consequences consequence NNS cord-303046-unksl7p4 59 55 of of IN cord-303046-unksl7p4 59 56 the the DT cord-303046-unksl7p4 59 57 coming come VBG cord-303046-unksl7p4 59 58 economic economic JJ cord-303046-unksl7p4 59 59 crisis crisis NN cord-303046-unksl7p4 59 60 . . . cord-303046-unksl7p4 60 1 Single single JJ cord-303046-unksl7p4 60 2 cell cell NN cord-303046-unksl7p4 60 3 RNA rna NN cord-303046-unksl7p4 60 4 sequencing sequencing NN cord-303046-unksl7p4 60 5 of of IN cord-303046-unksl7p4 60 6 13 13 CD cord-303046-unksl7p4 60 7 human human JJ cord-303046-unksl7p4 60 8 tissues tissue NNS cord-303046-unksl7p4 60 9 identify identify VB cord-303046-unksl7p4 60 10 cell cell NN cord-303046-unksl7p4 60 11 types type NNS cord-303046-unksl7p4 60 12 and and CC cord-303046-unksl7p4 60 13 receptors receptor NNS cord-303046-unksl7p4 60 14 of of IN cord-303046-unksl7p4 60 15 human human JJ cord-303046-unksl7p4 60 16 coronaviruses coronaviruse NNS cord-303046-unksl7p4 60 17 Specific Specific NNP cord-303046-unksl7p4 60 18 ACE2 ACE2 NNP cord-303046-unksl7p4 60 19 expression expression NN cord-303046-unksl7p4 60 20 in in IN cord-303046-unksl7p4 60 21 cholangiocytes cholangiocyte NNS cord-303046-unksl7p4 60 22 may may MD cord-303046-unksl7p4 60 23 cause cause VB cord-303046-unksl7p4 60 24 liver liver NN cord-303046-unksl7p4 60 25 damage damage NN cord-303046-unksl7p4 60 26 after after IN cord-303046-unksl7p4 60 27 2019-nCoV 2019-ncov CD cord-303046-unksl7p4 60 28 infection infection NN cord-303046-unksl7p4 60 29 COVID-19 covid-19 NN cord-303046-unksl7p4 60 30 : : : cord-303046-unksl7p4 60 31 abnormal abnormal JJ cord-303046-unksl7p4 60 32 liver liver NN cord-303046-unksl7p4 60 33 function function NN cord-303046-unksl7p4 60 34 tests test VBZ cord-303046-unksl7p4 60 35 Autopsy autopsy JJ cord-303046-unksl7p4 60 36 findings finding NNS cord-303046-unksl7p4 60 37 and and CC cord-303046-unksl7p4 60 38 venous venous JJ cord-303046-unksl7p4 60 39 thromboembolism thromboembolism NN cord-303046-unksl7p4 60 40 in in IN cord-303046-unksl7p4 60 41 patients patient NNS cord-303046-unksl7p4 60 42 with with IN cord-303046-unksl7p4 60 43 COVID-19 COVID-19 NNP cord-303046-unksl7p4 60 44 Metabolic Metabolic NNP cord-303046-unksl7p4 60 45 associated associate VBD cord-303046-unksl7p4 60 46 fatty fatty JJ cord-303046-unksl7p4 60 47 liver liver NN cord-303046-unksl7p4 60 48 disease disease NN cord-303046-unksl7p4 60 49 increases increase VBZ cord-303046-unksl7p4 61 1 COVID-19 covid-19 JJ cord-303046-unksl7p4 61 2 disease disease NN cord-303046-unksl7p4 61 3 severity severity NN cord-303046-unksl7p4 61 4 in in IN cord-303046-unksl7p4 61 5 non non JJ cord-303046-unksl7p4 61 6 - - JJ cord-303046-unksl7p4 61 7 diabetic diabetic JJ cord-303046-unksl7p4 61 8 patients patient NNS cord-303046-unksl7p4 61 9 Clinical clinical JJ cord-303046-unksl7p4 61 10 characteristics characteristic NNS cord-303046-unksl7p4 61 11 and and CC cord-303046-unksl7p4 61 12 outcomes outcome NNS cord-303046-unksl7p4 61 13 of of IN cord-303046-unksl7p4 61 14 COVID-19 covid-19 CD cord-303046-unksl7p4 61 15 among among IN cord-303046-unksl7p4 61 16 patients patient NNS cord-303046-unksl7p4 61 17 with with IN cord-303046-unksl7p4 61 18 pre pre JJ cord-303046-unksl7p4 61 19 - - JJ cord-303046-unksl7p4 61 20 existing existing JJ cord-303046-unksl7p4 61 21 liver liver NN cord-303046-unksl7p4 61 22 disease disease NN cord-303046-unksl7p4 61 23 in in IN cord-303046-unksl7p4 61 24 United United NNP cord-303046-unksl7p4 61 25 States States NNP cord-303046-unksl7p4 61 26 : : : cord-303046-unksl7p4 61 27 a a DT cord-303046-unksl7p4 61 28 multi multi JJ cord-303046-unksl7p4 61 29 - - JJ cord-303046-unksl7p4 61 30 center center JJ cord-303046-unksl7p4 61 31 research research NN cord-303046-unksl7p4 61 32 network network NN cord-303046-unksl7p4 61 33 study study NN cord-303046-unksl7p4 61 34 Prognosis Prognosis NNP cord-303046-unksl7p4 61 35 of of IN cord-303046-unksl7p4 61 36 COVID-19 COVID-19 NNP cord-303046-unksl7p4 61 37 in in IN cord-303046-unksl7p4 61 38 patients patient NNS cord-303046-unksl7p4 61 39 with with IN cord-303046-unksl7p4 61 40 liver liver NN cord-303046-unksl7p4 61 41 and and CC cord-303046-unksl7p4 61 42 kidney kidney NN cord-303046-unksl7p4 61 43 diseases disease NNS cord-303046-unksl7p4 61 44 : : : cord-303046-unksl7p4 61 45 an an DT cord-303046-unksl7p4 61 46 early early JJ cord-303046-unksl7p4 61 47 systematic systematic JJ cord-303046-unksl7p4 61 48 review review NN cord-303046-unksl7p4 61 49 and and CC cord-303046-unksl7p4 61 50 meta meta NNP cord-303046-unksl7p4 61 51 - - HYPH cord-303046-unksl7p4 61 52 analysis analysis NN cord-303046-unksl7p4 61 53 High high JJ cord-303046-unksl7p4 61 54 mortality mortality NN cord-303046-unksl7p4 61 55 rates rate NNS cord-303046-unksl7p4 61 56 for for IN cord-303046-unksl7p4 61 57 SARS SARS NNP cord-303046-unksl7p4 61 58 - - HYPH cord-303046-unksl7p4 61 59 CoV-2 CoV-2 NNP cord-303046-unksl7p4 61 60 infection infection NN cord-303046-unksl7p4 61 61 in in IN cord-303046-unksl7p4 61 62 patients patient NNS cord-303046-unksl7p4 61 63 with with IN cord-303046-unksl7p4 61 64 pre pre JJ cord-303046-unksl7p4 61 65 - - JJ cord-303046-unksl7p4 61 66 existing existing JJ cord-303046-unksl7p4 61 67 chronic chronic JJ cord-303046-unksl7p4 61 68 liver liver NN cord-303046-unksl7p4 61 69 disease disease NN cord-303046-unksl7p4 61 70 and and CC cord-303046-unksl7p4 61 71 cirrhosis cirrhosis NN cord-303046-unksl7p4 61 72 : : : cord-303046-unksl7p4 62 1 preliminary preliminary JJ cord-303046-unksl7p4 62 2 results result NNS cord-303046-unksl7p4 62 3 from from IN cord-303046-unksl7p4 62 4 an an DT cord-303046-unksl7p4 62 5 international international JJ cord-303046-unksl7p4 62 6 registry registry NN cord-303046-unksl7p4 62 7 The the DT cord-303046-unksl7p4 62 8 COVID-19 COVID-19 NNP cord-303046-unksl7p4 62 9 pandemic pandemic NN cord-303046-unksl7p4 62 10 will will MD cord-303046-unksl7p4 62 11 have have VB cord-303046-unksl7p4 62 12 a a DT cord-303046-unksl7p4 62 13 long long RB cord-303046-unksl7p4 62 14 - - HYPH cord-303046-unksl7p4 62 15 lasting last VBG cord-303046-unksl7p4 62 16 impact impact NN cord-303046-unksl7p4 62 17 on on IN cord-303046-unksl7p4 62 18 the the DT cord-303046-unksl7p4 62 19 quality quality NN cord-303046-unksl7p4 62 20 of of IN cord-303046-unksl7p4 62 21 cirrhosis cirrhosis NN cord-303046-unksl7p4 63 1 care care NN cord-303046-unksl7p4 64 1 COVID-19 covid-19 JJ cord-303046-unksl7p4 64 2 and and CC cord-303046-unksl7p4 64 3 viral viral JJ cord-303046-unksl7p4 64 4 hepatitis hepatitis NN cord-303046-unksl7p4 64 5 elimination elimination NN cord-303046-unksl7p4 64 6 programs program NNS cord-303046-unksl7p4 64 7 : : : cord-303046-unksl7p4 64 8 are be VBP cord-303046-unksl7p4 64 9 we -PRON- PRP cord-303046-unksl7p4 64 10 stepping step VBG cord-303046-unksl7p4 64 11 backward backward RB cord-303046-unksl7p4 64 12 ? ? . cord-303046-unksl7p4 65 1 Liver liver NN cord-303046-unksl7p4 65 2 Int int NN cord-303046-unksl7p4 66 1 The the DT cord-303046-unksl7p4 66 2 author author NN cord-303046-unksl7p4 66 3 has have VBZ cord-303046-unksl7p4 66 4 served serve VBN cord-303046-unksl7p4 66 5 as as IN cord-303046-unksl7p4 66 6 an an DT cord-303046-unksl7p4 66 7 advisor advisor NN cord-303046-unksl7p4 66 8 for for IN cord-303046-unksl7p4 66 9 Abbvie Abbvie NNP cord-303046-unksl7p4 66 10 , , , cord-303046-unksl7p4 66 11 Gilead Gilead NNP cord-303046-unksl7p4 66 12 , , , cord-303046-unksl7p4 66 13 GlaxoSmithKline GlaxoSmithKline NNP cord-303046-unksl7p4 66 14 , , , cord-303046-unksl7p4 66 15 Merck Merck NNP cord-303046-unksl7p4 66 16 , , , cord-303046-unksl7p4 66 17 Regulus Regulus NNP cord-303046-unksl7p4 66 18 and and CC cord-303046-unksl7p4 66 19 Siemens Siemens NNP cord-303046-unksl7p4 66 20 Healthcare Healthcare NNP cord-303046-unksl7p4 66 21 . . . cord-303046-unksl7p4 67 1 CoVID-19 CoVID-19 NNP cord-303046-unksl7p4 68 1 Dashboard dashboard NN cord-303046-unksl7p4 68 2 by by IN cord-303046-unksl7p4 68 3 the the DT cord-303046-unksl7p4 68 4 Center Center NNP cord-303046-unksl7p4 68 5 for for IN cord-303046-unksl7p4 68 6 Systems Systems NNP cord-303046-unksl7p4 68 7 Science Science NNP cord-303046-unksl7p4 68 8 and and CC cord-303046-unksl7p4 68 9 engineering engineering NN cord-303046-unksl7p4 68 10 at at IN cord-303046-unksl7p4 68 11 Johns Johns NNP cord-303046-unksl7p4 68 12 Hopkins Hopkins NNP cord-303046-unksl7p4 68 13 University University NNP cord-303046-unksl7p4 68 14 , , , cord-303046-unksl7p4 68 15 Baltimore Baltimore NNP cord-303046-unksl7p4 68 16 , , , cord-303046-unksl7p4 68 17 maryland maryland NNP cord-303046-unksl7p4 68 18 : : : cord-303046-unksl7p4 69 1 https://systems.jhu.edu/ https://systems.jhu.edu/ NNP cord-303046-unksl7p4 69 2 WHo who WP cord-303046-unksl7p4 69 3 Global Global NNP cord-303046-unksl7p4 69 4 Hepatitis Hepatitis NNP cord-303046-unksl7p4 69 5 Report Report NNP cord-303046-unksl7p4 69 6 2017 2017 CD cord-303046-unksl7p4 69 7 : : : cord-303046-unksl7p4 70 1 https://www.who.int/hepatitis/ https://www.who.int/hepatitis/ NNP cord-303046-unksl7p4 70 2 publications publication NNS cord-303046-unksl7p4 70 3 / / SYM cord-303046-unksl7p4 70 4 global global JJ cord-303046-unksl7p4 70 5 - - HYPH cord-303046-unksl7p4 70 6 hepatitis hepatitis NN cord-303046-unksl7p4 70 7 - - HYPH cord-303046-unksl7p4 70 8 report2017 report2017 NNP cord-303046-unksl7p4 70 9 / / SYM cord-303046-unksl7p4 70 10 en/ en/ XX