id author title date pages extension mime words sentences flesch summary cache txt cord-024141-9sdbhw2g Liu, Haiyan Lung and Mediastinum 2017-09-02 .txt text/plain 7361 650 44 • The 2015 World Health Organization (WHO) classification of tumors of the lung specifies that immunohistochemistry is required for lung cancer diagnosis, not only for small biopsies and fine needle aspiration (FNA) specimens but also for certain resected specimens such as solid adenocarcinoma (ADC), nonkeratinizing squamous cell carcinoma, large cell carcinoma, neuroendocrine tumors, and sarcomatoid carcinomas. • The role of cytopathologists has expanded to not only making a specific diagnosis, including histopathological subtyping of tumors, but also to thoughtfully utilizing the limited material for necessary genetic studies to help personalize treatment strategies for advanced lung cancer patients. Representative images of the FNA smears and cellblock material were shown in Fig. 6 .39a-d.The cytological features raise a differential diagnosis that includes neuroendocrine tumor, spindle cell tumors, including sarcomatoid carcinoma and metastatic melanoma of the spindle cell type. ./cache/cord-024141-9sdbhw2g.txt ./txt/cord-024141-9sdbhw2g.txt