id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-268729-n7slf5tx	Wissinger, E L	Manipulation of acute inflammatory lung disease	2008-05-07		.txt	text/plain	10085	562	36	Their role in limiting lung inflammation can be clearly seen in respiratory syncytial virus (RSV)infected mice where pDC depletion leads to increased viral replication and enhanced immunopathology in the lungs 70, 71 . TNF receptor-II and very late antigen--1 synergize to protect CD8 T cells in the influenza virus infected airways from apoptosis, 110 whereas engagement of Qa-1b by CD94 / NKG2A transmits a negative signal that limits immune pathology. 128 Therapeutic administration of antibodies that block macrophage inflammatory protein-2 during influenza infection reduces neutrophil recruitment by 49 % and improves lung pathology without altering viral clearance. Viruses induce local production of IFN-by T and non-T cells in the respiratory tract, and its neutralization not only reduces local lung cellularity and systemic humoral responses to influenza virus infection in mice, 207 but may also delay viral clearance. Plasmacytoid dendritic cells limit viral replication, pulmonary infl ammation, and airway hyperresponsiveness in respiratory syncytial virus infection	./cache/cord-268729-n7slf5tx.txt	./txt/cord-268729-n7slf5tx.txt