id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-290226-rtoasm2l	Scassellati, Catia	Ozone: a natural bioactive molecule with antioxidant property as potential new strategy in aging and in neurodegenerative disorders	2020-08-15		.txt	text/plain	15536	1112	42	In addition, Nrf2 regulates also the constitutive and inducible expression of antioxidants including, but not limited to, Superoxide Dismutases (SOD), Glutathione Peroxidase (GSH-Px), Glutathione-S-Transferase (GST), Catalase (CAT), NADPH quinone oxidoreductase 1 (NQO1), phase II enzymes of drug metabolism and HSPs (Galie et al., 2018 , Bocci, V., Valacchi, 2015 , Pedruzzi et al., 2012 (Figure 1) . We observed that OzoneOP exerts a protective effect on ischemia-reperfusion injury (IRI) in rat models of cochlear, hepatic, intestinal, renal, cardiac, lung and skeletal ischemia through an oxidative preconditioning mechanism that prevents the increase of the endogenous pro-oxidant and stimulates antioxidant mechanisms (Table 2 ). Modulation of age-related changes in oxidative stress markers and energy status in the rat heart and hippocampus: a significant role for ozone therapy	./cache/cord-290226-rtoasm2l.txt	./txt/cord-290226-rtoasm2l.txt