id author title date pages extension mime words sentences flesch summary cache txt cord-329066-9xo5zztv Yuan, Kai FGL2 is positively correlated with enhanced antitumor responses mediated by T cells in lung adenocarcinoma 2020-03-13 .txt text/plain 5139 293 47 A high expression level of FGL2 was correlated with better prognostic outcomes of lung adenocarcinoma patients, including overall survival and progression-free survival. Thus, we propose that high FGL2 expression, which is positively associated with enhanced antitumor activities mediated by T cells, is a beneficial marker for lung adenocarcinoma treatment outcomes. We used the TIMER database to explore the correlation between immune cell infiltration and FGL2 expression in lung adenocarcinoma. GO analysis indicated that FGL2-correlated genes were enriched in the immune response, the adaptive immune response, the positive regulation of T cell proliferation, the positive regulation of interferon-gamma production, the positive regulation of tumor necrosis factor production, T cell activation, the interferon-gamma-mediated signaling pathway, T cell costimulation, T cell differentiation, the T cell receptor signaling pathway, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, etc (Fig. 4A) . ./cache/cord-329066-9xo5zztv.txt ./txt/cord-329066-9xo5zztv.txt