id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-343842-2klytw6c	Takamura, Shiki	Persistence in Temporary Lung Niches: A Survival Strategy of Lung-Resident Memory CD8(+) T Cells	2017-07-01		.txt	text/plain	10329	427	44	This review will focus primarily on influenza and parainfluenza virus infections and discuss recent insights into the course of CD8 + T RM cell establishment in the lung interstitium/ parenchyma and airways, from initial priming, to tissue migration, local differentiation, and maintenance. This influx (3-5 days) is a part of acute response during respiratory virus infections (44) , and antigen-nonspecific memory CD8 + T cells recruited to the lung airways provide ''innate'' protection (64) . Nevertheless, the lack of CCR5 alone has essentially no impact on the active recruitment of expanded antigen-specific effector CD8 + T cells to the lung (5-10 days) (30, 66) , suggesting the redundancy of signals through various inflammatory chemokine receptors in this process. Cutting edge: antigen is not required for the activation and maintenance of virus-specific memory CD8 + T cells in the lung airways	./cache/cord-343842-2klytw6c.txt	./txt/cord-343842-2klytw6c.txt