id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-023055-ntbvmssh	nan	Immunogenicity	2004-02-19		.txt	text/plain	64563	3952	59	Antigen is internalized into acidic vesicles, proteolyzed, and peptides containing T ceU antigenic determinants are transported to the APC surface where they are recognized by the antigen-specific T cell in conjunction with Ia. Most Ia-"pressing cells are competent APC, however, only B cells have antigen-specilic receptors on their surface aUowing bound antigen to be processed and presented at 1/lW the antigen concentration required by nonspecific APC Little is known about B cell antigen processing function during differentiation, or if Ig-mediated APC function is altered at different maturational stages, thus allowing regulation of B cell-helper T cell interactions. These results indicate that the poor response of murine CTL to human class I antigens is not determined by selection in the thymus, but by species-specific constraints on the interaction of MHC antigens with T-cell recognition structures.	./cache/cord-023055-ntbvmssh.txt	./txt/cord-023055-ntbvmssh.txt