id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-334592-54dofkxh	Levine, Beth	Autophagy in immunity and inflammation	2011-01-20		.txt	text/plain	10249	418	29	Moreover, p62 is required for starvation and IFN-γ-induced targeting of Fau (and perhaps other ubiquitylated protein complexes) to mycobacteria-containing phagosomes, resulting in the generation of antimycobacterial Fau-derived peptides 42 .The role of p62 in innate immunity is probably evolutionarily ancient, as the Drosophila p62 orthologue REF(2)P was originally identified in a screen for modifiers of sigma virus replication 43 . The mechanisms by which autophagy genes mediate in vivo resistance to infection are not fully understood, but are likely to involve a combination of xenophagy, other autophagy-protein-dependent effects on microbial replication or survival, activation of innate and adaptive immune responses, and/or alterations in pathogen-induced cell death (Fig. 3 ).	./cache/cord-334592-54dofkxh.txt	./txt/cord-334592-54dofkxh.txt