id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-010252-go8cmgpo	Masihi, K.Noel	Muramyl peptides confer hepatoprotection against murine viral hepatitis	2006-03-15		.txt	text/plain	2236	125	45	The hepatoprotection induced by synthetic muramyl peptides was investigated using a model of lethal murine mouse hepatitis MHV-3 virus infection. MDP and a nonpyrogenic analog, Murametide, inhibited the steep elevation of serum transaminases induced by MHV-3 irrespective of whether the immunomodulators were administered before or after the infection. In the present study, the effect of MDP and a nonpyrogenic analog, Murametide, on biochemical and other parameters was investigated using a model of lethal routine MHV-3 virus infection. In contrast, the MHV-3 infection induced increased GOT and GPT activities on day 3 and the enzyme levels were elevated even further on day 4, a time period when many of the animals were dying. Protective effect of muramyl dipeptide analogs in combination with trehalose dimycolate against aerogenic influenza and Mycobacterium tuberculosis infections in mice	./cache/cord-010252-go8cmgpo.txt	./txt/cord-010252-go8cmgpo.txt