id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-336416-vas0b6dt	Wege, H.	NEUROVIRULENCE AND PERSISTENCY OF MOUSE HEPATITIS VIRUSES IN RATS 1 1 Supported by the Deutsche Forschungsgemeinschaft and Hertie-Stiftung	1980-12-31		.txt	text/plain	1343	84	46	ABSTRACT The murine coronavirus JHM induces in weanling rats different types of central nervous diseases ranging from an acute panencephalitis to a late demyelinating encephalomyelitis. Of particular interest are the central nervous system (CNS) diseases associated with this virus group, especially the mouse hepatitis virus strain JHM reveals a distinct neurovirulence for mice and rats (1, 2, 3, 4) . In the present communication the neurovirulence of four murine coronavirus strains (MHV 1, MHV 2, MHV 3 and MHV A59) for rats is compared to the JHM virus. The occurrence and rate of the different types of CNS disease induced by JHM virus is associated with the properties of the virus preparation used as inoculum as summarized in table 2. Reisolated mutants from diseased animals with LDE did not always maintain their temperature sensitivity but were different from revertants by the type of neurovirulence.	./cache/cord-336416-vas0b6dt.txt	./txt/cord-336416-vas0b6dt.txt