id	sid	tid	token	lemma	pos
cord-256444-grw5s2pf	1	1	key	key	JJ
cord-256444-grw5s2pf	1	2	:	:	:
cord-256444-grw5s2pf	1	3	cord-256444-grw5s2pf	cord-256444-grw5s2pf	CD
cord-256444-grw5s2pf	1	4	authors	author	NNS
cord-256444-grw5s2pf	1	5	:	:	:
cord-256444-grw5s2pf	1	6	Lai	Lai	NNP
cord-256444-grw5s2pf	1	7	,	,	,
cord-256444-grw5s2pf	1	8	Michael	Michael	NNP
cord-256444-grw5s2pf	1	9	M.C.	M.C.	NNP
cord-256444-grw5s2pf	1	10	;	;	:
cord-256444-grw5s2pf	1	11	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	1	12	,	,	,
cord-256444-grw5s2pf	2	1	David	David	NNP
cord-256444-grw5s2pf	2	2	title	title	NN
cord-256444-grw5s2pf	2	3	:	:	:
cord-256444-grw5s2pf	3	1	The	the	DT
cord-256444-grw5s2pf	3	2	Molecular	Molecular	NNP
cord-256444-grw5s2pf	3	3	Biology	Biology	NNP
cord-256444-grw5s2pf	3	4	of	of	IN
cord-256444-grw5s2pf	3	5	Coronaviruses	Coronaviruses	NNP
cord-256444-grw5s2pf	3	6	date	date	NN
cord-256444-grw5s2pf	3	7	:	:	:
cord-256444-grw5s2pf	3	8	1997	1997	CD
cord-256444-grw5s2pf	3	9	-	-	SYM
cord-256444-grw5s2pf	3	10	12	12	CD
cord-256444-grw5s2pf	3	11	-	-	SYM
cord-256444-grw5s2pf	3	12	31	31	CD
cord-256444-grw5s2pf	3	13	journal	journal	NN
cord-256444-grw5s2pf	3	14	:	:	:
cord-256444-grw5s2pf	4	1	Advances	advance	NNS
cord-256444-grw5s2pf	4	2	in	in	IN
cord-256444-grw5s2pf	4	3	Virus	Virus	NNP
cord-256444-grw5s2pf	4	4	Research	Research	NNP
cord-256444-grw5s2pf	4	5	DOI	DOI	NNP
cord-256444-grw5s2pf	4	6	:	:	:
cord-256444-grw5s2pf	4	7	10.1016	10.1016	CD
cord-256444-grw5s2pf	4	8	/	/	SYM
cord-256444-grw5s2pf	4	9	s0065	s0065	NNP
cord-256444-grw5s2pf	4	10	-	-	HYPH
cord-256444-grw5s2pf	4	11	3527(08)60286	3527(08)60286	NNP
cord-256444-grw5s2pf	4	12	-	-	HYPH
cord-256444-grw5s2pf	4	13	9	9	CD
cord-256444-grw5s2pf	4	14	sha	sha	NN
cord-256444-grw5s2pf	4	15	:	:	:
cord-256444-grw5s2pf	5	1	fdf4ba813d856f611638edcf7d2233569bb13ef2	fdf4ba813d856f611638edcf7d2233569bb13ef2	NNP
cord-256444-grw5s2pf	5	2	doc_id	doc_id	NNP
cord-256444-grw5s2pf	5	3	:	:	:
cord-256444-grw5s2pf	5	4	256444	256444	CD
cord-256444-grw5s2pf	5	5	cord_uid	cord_uid	NNS
cord-256444-grw5s2pf	5	6	:	:	:
cord-256444-grw5s2pf	6	1	grw5s2pf	grw5s2pf	NNP
cord-256444-grw5s2pf	7	1	Publisher	Publisher	NNP
cord-256444-grw5s2pf	7	2	Summary	Summary	NNP
cord-256444-grw5s2pf	8	1	This	this	DT
cord-256444-grw5s2pf	8	2	chapter	chapter	NN
cord-256444-grw5s2pf	8	3	discusses	discuss	VBZ
cord-256444-grw5s2pf	8	4	the	the	DT
cord-256444-grw5s2pf	8	5	manipulation	manipulation	NN
cord-256444-grw5s2pf	8	6	of	of	IN
cord-256444-grw5s2pf	8	7	clones	clone	NNS
cord-256444-grw5s2pf	8	8	of	of	IN
cord-256444-grw5s2pf	8	9	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	8	10	and	and	CC
cord-256444-grw5s2pf	8	11	of	of	IN
cord-256444-grw5s2pf	8	12	complementary	complementary	JJ
cord-256444-grw5s2pf	8	13	DNAs	dna	NNS
cord-256444-grw5s2pf	8	14	(	(	-LRB-
cord-256444-grw5s2pf	8	15	cDNAs	cDNAs	NNPS
cord-256444-grw5s2pf	8	16	)	)	-RRB-
cord-256444-grw5s2pf	8	17	of	of	IN
cord-256444-grw5s2pf	8	18	defective	defective	JJ
cord-256444-grw5s2pf	8	19	-	-	HYPH
cord-256444-grw5s2pf	8	20	interfering	interfere	VBG
cord-256444-grw5s2pf	8	21	(	(	-LRB-
cord-256444-grw5s2pf	8	22	DI	DI	NNP
cord-256444-grw5s2pf	8	23	)	)	-RRB-
cord-256444-grw5s2pf	8	24	RNAs	rna	NNS
cord-256444-grw5s2pf	8	25	to	to	TO
cord-256444-grw5s2pf	8	26	study	study	VB
cord-256444-grw5s2pf	8	27	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	8	28	RNA	RNA	NNP
cord-256444-grw5s2pf	8	29	replication	replication	NN
cord-256444-grw5s2pf	8	30	,	,	,
cord-256444-grw5s2pf	8	31	transcription	transcription	NN
cord-256444-grw5s2pf	8	32	,	,	,
cord-256444-grw5s2pf	8	33	recombination	recombination	NN
cord-256444-grw5s2pf	8	34	,	,	,
cord-256444-grw5s2pf	8	35	processing	processing	NN
cord-256444-grw5s2pf	8	36	and	and	CC
cord-256444-grw5s2pf	8	37	transport	transport	NN
cord-256444-grw5s2pf	8	38	of	of	IN
cord-256444-grw5s2pf	8	39	proteins	protein	NNS
cord-256444-grw5s2pf	8	40	,	,	,
cord-256444-grw5s2pf	8	41	virion	virion	NN
cord-256444-grw5s2pf	8	42	assembly	assembly	NN
cord-256444-grw5s2pf	8	43	,	,	,
cord-256444-grw5s2pf	8	44	identification	identification	NN
cord-256444-grw5s2pf	8	45	of	of	IN
cord-256444-grw5s2pf	8	46	cell	cell	NN
cord-256444-grw5s2pf	8	47	receptors	receptor	NNS
cord-256444-grw5s2pf	8	48	for	for	IN
cord-256444-grw5s2pf	8	49	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	8	50	,	,	,
cord-256444-grw5s2pf	8	51	and	and	CC
cord-256444-grw5s2pf	8	52	processing	processing	NN
cord-256444-grw5s2pf	8	53	of	of	IN
cord-256444-grw5s2pf	8	54	the	the	DT
cord-256444-grw5s2pf	8	55	polymerase	polymerase	NN
cord-256444-grw5s2pf	8	56	.	.	.
cord-256444-grw5s2pf	9	1	The	the	DT
cord-256444-grw5s2pf	9	2	nature	nature	NN
cord-256444-grw5s2pf	9	3	of	of	IN
cord-256444-grw5s2pf	9	4	the	the	DT
cord-256444-grw5s2pf	9	5	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	9	6	genome	genome	NN
cord-256444-grw5s2pf	9	7	is	be	VBZ
cord-256444-grw5s2pf	9	8	nonsegmented	nonsegmente	VBN
cord-256444-grw5s2pf	9	9	,	,	,
cord-256444-grw5s2pf	9	10	single	single	RB
cord-256444-grw5s2pf	9	11	-	-	HYPH
cord-256444-grw5s2pf	9	12	stranded	stranded	JJ
cord-256444-grw5s2pf	9	13	,	,	,
cord-256444-grw5s2pf	9	14	and	and	CC
cord-256444-grw5s2pf	9	15	positive	positive	JJ
cord-256444-grw5s2pf	9	16	-	-	HYPH
cord-256444-grw5s2pf	9	17	sense	sense	NN
cord-256444-grw5s2pf	9	18	RNA	RNA	NNP
cord-256444-grw5s2pf	9	19	.	.	.
cord-256444-grw5s2pf	10	1	Its	-PRON-	PRP$
cord-256444-grw5s2pf	10	2	size	size	NN
cord-256444-grw5s2pf	10	3	ranges	range	VBZ
cord-256444-grw5s2pf	10	4	from	from	IN
cord-256444-grw5s2pf	10	5	27	27	CD
cord-256444-grw5s2pf	10	6	to	to	TO
cord-256444-grw5s2pf	10	7	32	32	CD
cord-256444-grw5s2pf	10	8	kb	kb	NNP
cord-256444-grw5s2pf	10	9	,	,	,
cord-256444-grw5s2pf	10	10	which	which	WDT
cord-256444-grw5s2pf	10	11	is	be	VBZ
cord-256444-grw5s2pf	10	12	significantly	significantly	RB
cord-256444-grw5s2pf	10	13	larger	large	JJR
cord-256444-grw5s2pf	10	14	when	when	WRB
cord-256444-grw5s2pf	10	15	compared	compare	VBN
cord-256444-grw5s2pf	10	16	with	with	IN
cord-256444-grw5s2pf	10	17	other	other	JJ
cord-256444-grw5s2pf	10	18	RNA	RNA	NNP
cord-256444-grw5s2pf	10	19	viruses	virus	NNS
cord-256444-grw5s2pf	10	20	.	.	.
cord-256444-grw5s2pf	11	1	The	the	DT
cord-256444-grw5s2pf	11	2	gene	gene	NN
cord-256444-grw5s2pf	11	3	encoding	encode	VBG
cord-256444-grw5s2pf	11	4	the	the	DT
cord-256444-grw5s2pf	11	5	large	large	JJ
cord-256444-grw5s2pf	11	6	surface	surface	NN
cord-256444-grw5s2pf	11	7	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	11	8	is	be	VBZ
cord-256444-grw5s2pf	11	9	up	up	IN
cord-256444-grw5s2pf	11	10	to	to	TO
cord-256444-grw5s2pf	11	11	4.4	4.4	CD
cord-256444-grw5s2pf	11	12	kb	kb	NNS
cord-256444-grw5s2pf	11	13	,	,	,
cord-256444-grw5s2pf	11	14	encoding	encode	VBG
cord-256444-grw5s2pf	11	15	an	an	DT
cord-256444-grw5s2pf	11	16	imposing	impose	VBG
cord-256444-grw5s2pf	11	17	trimeric	trimeric	NN
cord-256444-grw5s2pf	11	18	,	,	,
cord-256444-grw5s2pf	11	19	highly	highly	RB
cord-256444-grw5s2pf	11	20	glycosylated	glycosylated	JJ
cord-256444-grw5s2pf	11	21	protein	protein	NN
cord-256444-grw5s2pf	11	22	.	.	.
cord-256444-grw5s2pf	12	1	This	this	DT
cord-256444-grw5s2pf	12	2	soars	soar	VBZ
cord-256444-grw5s2pf	12	3	some	some	DT
cord-256444-grw5s2pf	12	4	20	20	CD
cord-256444-grw5s2pf	12	5	nm	nm	NN
cord-256444-grw5s2pf	12	6	above	above	IN
cord-256444-grw5s2pf	12	7	the	the	DT
cord-256444-grw5s2pf	12	8	virion	virion	NN
cord-256444-grw5s2pf	12	9	envelope	envelope	NN
cord-256444-grw5s2pf	12	10	,	,	,
cord-256444-grw5s2pf	12	11	giving	give	VBG
cord-256444-grw5s2pf	12	12	the	the	DT
cord-256444-grw5s2pf	12	13	virus	virus	NN
cord-256444-grw5s2pf	12	14	the	the	DT
cord-256444-grw5s2pf	12	15	appearance	appearance	NN
cord-256444-grw5s2pf	12	16	-	-	:
cord-256444-grw5s2pf	12	17	with	with	IN
cord-256444-grw5s2pf	12	18	a	a	DT
cord-256444-grw5s2pf	12	19	little	little	JJ
cord-256444-grw5s2pf	12	20	imagination	imagination	NN
cord-256444-grw5s2pf	12	21	-	-	:
cord-256444-grw5s2pf	12	22	of	of	IN
cord-256444-grw5s2pf	12	23	a	a	DT
cord-256444-grw5s2pf	12	24	crown	crown	NN
cord-256444-grw5s2pf	12	25	or	or	CC
cord-256444-grw5s2pf	12	26	coronet	coronet	NN
cord-256444-grw5s2pf	12	27	.	.	.
cord-256444-grw5s2pf	13	1	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	13	2	research	research	NN
cord-256444-grw5s2pf	13	3	has	have	VBZ
cord-256444-grw5s2pf	13	4	contributed	contribute	VBN
cord-256444-grw5s2pf	13	5	to	to	IN
cord-256444-grw5s2pf	13	6	the	the	DT
cord-256444-grw5s2pf	13	7	understanding	understanding	NN
cord-256444-grw5s2pf	13	8	of	of	IN
cord-256444-grw5s2pf	13	9	many	many	JJ
cord-256444-grw5s2pf	13	10	aspects	aspect	NNS
cord-256444-grw5s2pf	13	11	of	of	IN
cord-256444-grw5s2pf	13	12	molecular	molecular	JJ
cord-256444-grw5s2pf	13	13	biology	biology	NN
cord-256444-grw5s2pf	13	14	in	in	IN
cord-256444-grw5s2pf	13	15	general	general	JJ
cord-256444-grw5s2pf	13	16	,	,	,
cord-256444-grw5s2pf	13	17	such	such	JJ
cord-256444-grw5s2pf	13	18	as	as	IN
cord-256444-grw5s2pf	13	19	the	the	DT
cord-256444-grw5s2pf	13	20	mechanism	mechanism	NN
cord-256444-grw5s2pf	13	21	of	of	IN
cord-256444-grw5s2pf	13	22	RNA	RNA	NNP
cord-256444-grw5s2pf	13	23	synthesis	synthesis	NN
cord-256444-grw5s2pf	13	24	,	,	,
cord-256444-grw5s2pf	13	25	translational	translational	JJ
cord-256444-grw5s2pf	13	26	control	control	NN
cord-256444-grw5s2pf	13	27	,	,	,
cord-256444-grw5s2pf	13	28	and	and	CC
cord-256444-grw5s2pf	13	29	protein	protein	NN
cord-256444-grw5s2pf	13	30	transport	transport	NN
cord-256444-grw5s2pf	13	31	and	and	CC
cord-256444-grw5s2pf	13	32	processing	processing	NN
cord-256444-grw5s2pf	13	33	.	.	.
cord-256444-grw5s2pf	14	1	It	-PRON-	PRP
cord-256444-grw5s2pf	14	2	remains	remain	VBZ
cord-256444-grw5s2pf	14	3	a	a	DT
cord-256444-grw5s2pf	14	4	treasure	treasure	NN
cord-256444-grw5s2pf	14	5	capable	capable	JJ
cord-256444-grw5s2pf	14	6	of	of	IN
cord-256444-grw5s2pf	14	7	generating	generate	VBG
cord-256444-grw5s2pf	14	8	unexpected	unexpected	JJ
cord-256444-grw5s2pf	14	9	insights	insight	NNS
cord-256444-grw5s2pf	14	10	.	.	.
cord-256444-grw5s2pf	15	1	viruses	virus	NNS
cord-256444-grw5s2pf	15	2	.	.	.
cord-256444-grw5s2pf	16	1	The	the	DT
cord-256444-grw5s2pf	16	2	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	16	3	polymerase	polymerase	NN
cord-256444-grw5s2pf	16	4	gene	gene	NN
cord-256444-grw5s2pf	16	5	alone	alone	RB
cord-256444-grw5s2pf	16	6	(	(	-LRB-
cord-256444-grw5s2pf	16	7	20	20	CD
cord-256444-grw5s2pf	16	8	-	-	SYM
cord-256444-grw5s2pf	16	9	22	22	CD
cord-256444-grw5s2pf	16	10	kb	kb	NNP
cord-256444-grw5s2pf	16	11	)	)	-RRB-
cord-256444-grw5s2pf	16	12	is	be	VBZ
cord-256444-grw5s2pf	16	13	about	about	RB
cord-256444-grw5s2pf	16	14	the	the	DT
cord-256444-grw5s2pf	16	15	same	same	JJ
cord-256444-grw5s2pf	16	16	size	size	NN
cord-256444-grw5s2pf	16	17	as	as	IN
cord-256444-grw5s2pf	16	18	the	the	DT
cord-256444-grw5s2pf	16	19	whole	whole	NN
cord-256444-grw5s2pf	16	20	of	of	IN
cord-256444-grw5s2pf	16	21	the	the	DT
cord-256444-grw5s2pf	16	22	picornavirus	picornavirus	NNP
cord-256444-grw5s2pf	16	23	(-8	(-8	-LRB-
cord-256444-grw5s2pf	16	24	kb	kb	NNP
cord-256444-grw5s2pf	16	25	)	)	-RRB-
cord-256444-grw5s2pf	16	26	and	and	CC
cord-256444-grw5s2pf	16	27	vesicular	vesicular	JJ
cord-256444-grw5s2pf	16	28	stomatitis	stomatitis	NN
cord-256444-grw5s2pf	16	29	virus	virus	NN
cord-256444-grw5s2pf	16	30	(	(	-LRB-
cord-256444-grw5s2pf	16	31	-11	-11	IN
cord-256444-grw5s2pf	16	32	kb	kb	NNP
cord-256444-grw5s2pf	16	33	)	)	-RRB-
cord-256444-grw5s2pf	16	34	genomes	genome	NNS
cord-256444-grw5s2pf	16	35	added	add	VBN
cord-256444-grw5s2pf	16	36	together	together	RB
cord-256444-grw5s2pf	16	37	.	.	.
cord-256444-grw5s2pf	17	1	The	the	DT
cord-256444-grw5s2pf	17	2	gene	gene	NN
cord-256444-grw5s2pf	17	3	encoding	encode	VBG
cord-256444-grw5s2pf	17	4	the	the	DT
cord-256444-grw5s2pf	17	5	large	large	JJ
cord-256444-grw5s2pf	17	6	surface	surface	NN
cord-256444-grw5s2pf	17	7	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	17	8	is	be	VBZ
cord-256444-grw5s2pf	17	9	up	up	IN
cord-256444-grw5s2pf	17	10	to	to	TO
cord-256444-grw5s2pf	17	11	4.4	4.4	CD
cord-256444-grw5s2pf	17	12	kb	kb	NNS
cord-256444-grw5s2pf	17	13	,	,	,
cord-256444-grw5s2pf	17	14	encoding	encode	VBG
cord-256444-grw5s2pf	17	15	an	an	DT
cord-256444-grw5s2pf	17	16	imposing	impose	VBG
cord-256444-grw5s2pf	17	17	trimeric	trimeric	NN
cord-256444-grw5s2pf	17	18	,	,	,
cord-256444-grw5s2pf	17	19	highly	highly	RB
cord-256444-grw5s2pf	17	20	glycosylated	glycosylated	JJ
cord-256444-grw5s2pf	17	21	protein	protein	NN
cord-256444-grw5s2pf	17	22	.	.	.
cord-256444-grw5s2pf	18	1	This	this	DT
cord-256444-grw5s2pf	18	2	soars	soar	VBZ
cord-256444-grw5s2pf	18	3	some	some	DT
cord-256444-grw5s2pf	18	4	20	20	CD
cord-256444-grw5s2pf	18	5	nm	nm	NN
cord-256444-grw5s2pf	18	6	above	above	IN
cord-256444-grw5s2pf	18	7	the	the	DT
cord-256444-grw5s2pf	18	8	virion	virion	NN
cord-256444-grw5s2pf	18	9	envelope	envelope	NN
cord-256444-grw5s2pf	18	10	,	,	,
cord-256444-grw5s2pf	18	11	giving	give	VBG
cord-256444-grw5s2pf	18	12	the	the	DT
cord-256444-grw5s2pf	18	13	virus	virus	NN
cord-256444-grw5s2pf	18	14	the	the	DT
cord-256444-grw5s2pf	18	15	appearance	appearance	NN
cord-256444-grw5s2pf	18	16	-	-	:
cord-256444-grw5s2pf	18	17	with	with	IN
cord-256444-grw5s2pf	18	18	a	a	DT
cord-256444-grw5s2pf	18	19	little	little	JJ
cord-256444-grw5s2pf	18	20	imagination	imagination	NN
cord-256444-grw5s2pf	18	21	-	-	:
cord-256444-grw5s2pf	18	22	of	of	IN
cord-256444-grw5s2pf	18	23	a	a	DT
cord-256444-grw5s2pf	18	24	crown	crown	NN
cord-256444-grw5s2pf	18	25	or	or	CC
cord-256444-grw5s2pf	18	26	coronet	coronet	NN
cord-256444-grw5s2pf	18	27	(	(	-LRB-
cord-256444-grw5s2pf	18	28	Latin	latin	JJ
cord-256444-grw5s2pf	18	29	corona	corona	NN
cord-256444-grw5s2pf	18	30	,	,	,
cord-256444-grw5s2pf	18	31	hence	hence	RB
cord-256444-grw5s2pf	18	32	the	the	DT
cord-256444-grw5s2pf	18	33	name	name	NN
cord-256444-grw5s2pf	18	34	of	of	IN
cord-256444-grw5s2pf	18	35	the	the	DT
cord-256444-grw5s2pf	18	36	genus	genus	NN
cord-256444-grw5s2pf	18	37	)	)	-RRB-
cord-256444-grw5s2pf	18	38	.	.	.
cord-256444-grw5s2pf	19	1	Coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	19	2	are	be	VBP
cord-256444-grw5s2pf	19	3	responsible	responsible	JJ
cord-256444-grw5s2pf	19	4	for	for	IN
cord-256444-grw5s2pf	19	5	a	a	DT
cord-256444-grw5s2pf	19	6	number	number	NN
cord-256444-grw5s2pf	19	7	of	of	IN
cord-256444-grw5s2pf	19	8	economically	economically	RB
cord-256444-grw5s2pf	19	9	important	important	JJ
cord-256444-grw5s2pf	19	10	diseases	disease	NNS
cord-256444-grw5s2pf	19	11	.	.	.
cord-256444-grw5s2pf	20	1	Avian	avian	JJ
cord-256444-grw5s2pf	20	2	infectious	infectious	JJ
cord-256444-grw5s2pf	20	3	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	20	4	virus	virus	NN
cord-256444-grw5s2pf	20	5	(	(	-LRB-
cord-256444-grw5s2pf	20	6	IBV	IBV	NNP
cord-256444-grw5s2pf	20	7	)	)	-RRB-
cord-256444-grw5s2pf	20	8	was	be	VBD
cord-256444-grw5s2pf	20	9	the	the	DT
cord-256444-grw5s2pf	20	10	first	first	JJ
cord-256444-grw5s2pf	20	11	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	20	12	to	to	TO
cord-256444-grw5s2pf	20	13	be	be	VB
cord-256444-grw5s2pf	20	14	isolated	isolate	VBN
cord-256444-grw5s2pf	20	15	,	,	,
cord-256444-grw5s2pf	20	16	from	from	IN
cord-256444-grw5s2pf	20	17	the	the	DT
cord-256444-grw5s2pf	20	18	domestic	domestic	JJ
cord-256444-grw5s2pf	20	19	fowl	fowl	NN
cord-256444-grw5s2pf	20	20	,	,	,
cord-256444-grw5s2pf	20	21	and	and	CC
cord-256444-grw5s2pf	20	22	propagated	propagate	VBD
cord-256444-grw5s2pf	20	23	in	in	IN
cord-256444-grw5s2pf	20	24	the	the	DT
cord-256444-grw5s2pf	20	25	1930s	1930	NNS
cord-256444-grw5s2pf	20	26	.	.	.
cord-256444-grw5s2pf	21	1	In	in	IN
cord-256444-grw5s2pf	21	2	addition	addition	NN
cord-256444-grw5s2pf	21	3	to	to	IN
cord-256444-grw5s2pf	21	4	respiratory	respiratory	JJ
cord-256444-grw5s2pf	21	5	disease	disease	NN
cord-256444-grw5s2pf	21	6	,	,	,
cord-256444-grw5s2pf	21	7	which	which	WDT
cord-256444-grw5s2pf	21	8	can	can	MD
cord-256444-grw5s2pf	21	9	predispose	predispose	VB
cord-256444-grw5s2pf	21	10	chickens	chicken	NNS
cord-256444-grw5s2pf	21	11	to	to	TO
cord-256444-grw5s2pf	21	12	possibly	possibly	RB
cord-256444-grw5s2pf	21	13	lethal	lethal	JJ
cord-256444-grw5s2pf	21	14	secondary	secondary	JJ
cord-256444-grw5s2pf	21	15	bacterial	bacterial	JJ
cord-256444-grw5s2pf	21	16	infections	infection	NNS
cord-256444-grw5s2pf	21	17	,	,	,
cord-256444-grw5s2pf	21	18	some	some	DT
cord-256444-grw5s2pf	21	19	strains	strain	NNS
cord-256444-grw5s2pf	21	20	also	also	RB
cord-256444-grw5s2pf	21	21	cause	cause	VBP
cord-256444-grw5s2pf	21	22	nephritis	nephritis	NN
cord-256444-grw5s2pf	21	23	(	(	-LRB-
cord-256444-grw5s2pf	21	24	King	King	NNP
cord-256444-grw5s2pf	21	25	and	and	CC
cord-256444-grw5s2pf	21	26	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	21	27	,	,	,
cord-256444-grw5s2pf	21	28	1991	1991	CD
cord-256444-grw5s2pf	21	29	;	;	:
cord-256444-grw5s2pf	21	30	Cook	Cook	NNP
cord-256444-grw5s2pf	21	31	and	and	CC
cord-256444-grw5s2pf	21	32	Mockett	Mockett	NNP
cord-256444-grw5s2pf	21	33	,	,	,
cord-256444-grw5s2pf	21	34	1995	1995	CD
cord-256444-grw5s2pf	21	35	)	)	-RRB-
cord-256444-grw5s2pf	21	36	.	.	.
cord-256444-grw5s2pf	22	1	Porcine	porcine	JJ
cord-256444-grw5s2pf	22	2	transmissible	transmissible	JJ
cord-256444-grw5s2pf	22	3	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	22	4	virus	virus	NN
cord-256444-grw5s2pf	22	5	(	(	-LRB-
cord-256444-grw5s2pf	22	6	TGEV	TGEV	NNP
cord-256444-grw5s2pf	22	7	)	)	-RRB-
cord-256444-grw5s2pf	22	8	causes	cause	VBZ
cord-256444-grw5s2pf	22	9	devastating	devastate	VBG
cord-256444-grw5s2pf	22	10	disease	disease	NN
cord-256444-grw5s2pf	22	11	in	in	IN
cord-256444-grw5s2pf	22	12	newborn	newborn	JJ
cord-256444-grw5s2pf	22	13	pigs	pig	NNS
cord-256444-grw5s2pf	22	14	,	,	,
cord-256444-grw5s2pf	22	15	with	with	IN
cord-256444-grw5s2pf	22	16	mortality	mortality	NN
cord-256444-grw5s2pf	22	17	often	often	RB
cord-256444-grw5s2pf	22	18	approaching	approach	VBG
cord-256444-grw5s2pf	22	19	100	100	CD
cord-256444-grw5s2pf	22	20	%	%	NN
cord-256444-grw5s2pf	22	21	(	(	-LRB-
cord-256444-grw5s2pf	22	22	Enjuanes	Enjuanes	NNP
cord-256444-grw5s2pf	22	23	and	and	CC
cord-256444-grw5s2pf	22	24	van	van	NNP
cord-256444-grw5s2pf	22	25	der	der	NNP
cord-256444-grw5s2pf	22	26	Zeijst	Zeijst	NNP
cord-256444-grw5s2pf	22	27	,	,	,
cord-256444-grw5s2pf	22	28	1995	1995	CD
cord-256444-grw5s2pf	22	29	)	)	-RRB-
cord-256444-grw5s2pf	22	30	.	.	.
cord-256444-grw5s2pf	23	1	Intriguingly	intriguingly	RB
cord-256444-grw5s2pf	23	2	,	,	,
cord-256444-grw5s2pf	23	3	there	there	EX
cord-256444-grw5s2pf	23	4	are	be	VBP
cord-256444-grw5s2pf	23	5	also	also	RB
cord-256444-grw5s2pf	23	6	naturally	naturally	RB
cord-256444-grw5s2pf	23	7	occurring	occur	VBG
cord-256444-grw5s2pf	23	8	mutants	mutant	NNS
cord-256444-grw5s2pf	23	9	[	[	-LRB-
cord-256444-grw5s2pf	23	10	i.e.	i.e.	FW
cord-256444-grw5s2pf	23	11	,	,	,
cord-256444-grw5s2pf	23	12	porcine	porcine	JJ
cord-256444-grw5s2pf	23	13	respiratory	respiratory	JJ
cord-256444-grw5s2pf	23	14	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	23	15	(	(	-LRB-
cord-256444-grw5s2pf	23	16	PRCV	PRCV	NNP
cord-256444-grw5s2pf	23	17	)	)	-RRB-
cord-256444-grw5s2pf	23	18	]	]	-RRB-
cord-256444-grw5s2pf	23	19	of	of	IN
cord-256444-grw5s2pf	23	20	TGEV	TGEV	NNP
cord-256444-grw5s2pf	23	21	which	which	WDT
cord-256444-grw5s2pf	23	22	cause	cause	VBP
cord-256444-grw5s2pf	23	23	only	only	RB
cord-256444-grw5s2pf	23	24	mild	mild	JJ
cord-256444-grw5s2pf	23	25	respiratory	respiratory	JJ
cord-256444-grw5s2pf	23	26	disease	disease	NN
cord-256444-grw5s2pf	23	27	and	and	CC
cord-256444-grw5s2pf	23	28	no	no	DT
cord-256444-grw5s2pf	23	29	enteritis	enteritis	NN
cord-256444-grw5s2pf	23	30	.	.	.
cord-256444-grw5s2pf	24	1	Several	several	JJ
cord-256444-grw5s2pf	24	2	other	other	JJ
cord-256444-grw5s2pf	24	3	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	24	4	also	also	RB
cord-256444-grw5s2pf	24	5	cause	cause	VBP
cord-256444-grw5s2pf	24	6	enteritis	enteritis	NN
cord-256444-grw5s2pf	24	7	:	:	:
cord-256444-grw5s2pf	24	8	bovine	bovine	JJ
cord-256444-grw5s2pf	24	9	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	24	10	(	(	-LRB-
cord-256444-grw5s2pf	24	11	BCV	BCV	NNP
cord-256444-grw5s2pf	24	12	)	)	-RRB-
cord-256444-grw5s2pf	24	13	,	,	,
cord-256444-grw5s2pf	24	14	turkey	turkey	NN
cord-256444-grw5s2pf	24	15	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	24	16	(	(	-LRB-
cord-256444-grw5s2pf	24	17	TCV	TCV	NNP
cord-256444-grw5s2pf	24	18	;	;	:
cord-256444-grw5s2pf	24	19	bluecomb	bluecomb	NNP
cord-256444-grw5s2pf	24	20	virus	virus	NN
cord-256444-grw5s2pf	24	21	)	)	-RRB-
cord-256444-grw5s2pf	24	22	,	,	,
cord-256444-grw5s2pf	24	23	feline	feline	JJ
cord-256444-grw5s2pf	24	24	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	24	25	(	(	-LRB-
cord-256444-grw5s2pf	24	26	FCV	FCV	NNP
cord-256444-grw5s2pf	24	27	)	)	-RRB-
cord-256444-grw5s2pf	24	28	,	,	,
cord-256444-grw5s2pf	24	29	canine	canine	JJ
cord-256444-grw5s2pf	24	30	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	24	31	(	(	-LRB-
cord-256444-grw5s2pf	24	32	CCV	CCV	NNP
cord-256444-grw5s2pf	24	33	)	)	-RRB-
cord-256444-grw5s2pf	24	34	and	and	CC
cord-256444-grw5s2pf	24	35	porcine	porcine	JJ
cord-256444-grw5s2pf	24	36	epidemic	epidemic	NN
cord-256444-grw5s2pf	24	37	diarrhea	diarrhea	NN
cord-256444-grw5s2pf	24	38	virus	virus	NN
cord-256444-grw5s2pf	24	39	(	(	-LRB-
cord-256444-grw5s2pf	24	40	PEDV	PEDV	NNP
cord-256444-grw5s2pf	24	41	)	)	-RRB-
cord-256444-grw5s2pf	24	42	.	.	.
cord-256444-grw5s2pf	25	1	FCV	FCV	NNP
cord-256444-grw5s2pf	25	2	may	may	MD
cord-256444-grw5s2pf	25	3	also	also	RB
cord-256444-grw5s2pf	25	4	cause	cause	VB
cord-256444-grw5s2pf	25	5	feline	feline	JJ
cord-256444-grw5s2pf	25	6	infectious	infectious	JJ
cord-256444-grw5s2pf	25	7	peritonitis	peritonitis	NN
cord-256444-grw5s2pf	25	8	.	.	.
cord-256444-grw5s2pf	26	1	An	an	DT
cord-256444-grw5s2pf	26	2	FCV	FCV	NNP
cord-256444-grw5s2pf	26	3	has	have	VBZ
cord-256444-grw5s2pf	26	4	been	be	VBN
cord-256444-grw5s2pf	26	5	isolated	isolate	VBN
cord-256444-grw5s2pf	26	6	from	from	IN
cord-256444-grw5s2pf	26	7	a	a	DT
cord-256444-grw5s2pf	26	8	cheetah	cheetah	NN
cord-256444-grw5s2pf	26	9	and	and	CC
cord-256444-grw5s2pf	26	10	BCVs	bcv	NNS
cord-256444-grw5s2pf	26	11	from	from	IN
cord-256444-grw5s2pf	26	12	wild	wild	JJ
cord-256444-grw5s2pf	26	13	sambar	sambar	NN
cord-256444-grw5s2pf	26	14	deer	deer	NN
cord-256444-grw5s2pf	26	15	and	and	CC
cord-256444-grw5s2pf	26	16	waterbuck	waterbuck	NNP
cord-256444-grw5s2pf	26	17	(	(	-LRB-
cord-256444-grw5s2pf	26	18	Tsunemitsu	Tsunemitsu	NNP
cord-256444-grw5s2pf	26	19	et	et	FW
cord-256444-grw5s2pf	26	20	al	al	NNP
cord-256444-grw5s2pf	26	21	.	.	NNP
cord-256444-grw5s2pf	26	22	,	,	,
cord-256444-grw5s2pf	26	23	1995	1995	CD
cord-256444-grw5s2pf	26	24	)	)	-RRB-
cord-256444-grw5s2pf	26	25	.	.	.
cord-256444-grw5s2pf	27	1	These	these	DT
cord-256444-grw5s2pf	27	2	BCVs	bcv	NNS
cord-256444-grw5s2pf	27	3	caused	cause	VBD
cord-256444-grw5s2pf	27	4	enteritis	enteritis	NN
cord-256444-grw5s2pf	27	5	when	when	WRB
cord-256444-grw5s2pf	27	6	inoculated	inoculate	VBN
cord-256444-grw5s2pf	27	7	into	into	IN
cord-256444-grw5s2pf	27	8	domestic	domestic	JJ
cord-256444-grw5s2pf	27	9	calves	calf	NNS
cord-256444-grw5s2pf	27	10	.	.	.
cord-256444-grw5s2pf	28	1	Humans	human	NNS
cord-256444-grw5s2pf	28	2	are	be	VBP
cord-256444-grw5s2pf	28	3	known	know	VBN
cord-256444-grw5s2pf	28	4	to	to	TO
cord-256444-grw5s2pf	28	5	suffer	suffer	VB
cord-256444-grw5s2pf	28	6	from	from	IN
cord-256444-grw5s2pf	28	7	two	two	CD
cord-256444-grw5s2pf	28	8	very	very	RB
cord-256444-grw5s2pf	28	9	different	different	JJ
cord-256444-grw5s2pf	28	10	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	28	11	,	,	,
cord-256444-grw5s2pf	28	12	human	human	JJ
cord-256444-grw5s2pf	28	13	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	28	14	(	(	-LRB-
cord-256444-grw5s2pf	28	15	HCV	HCV	NNP
cord-256444-grw5s2pf	28	16	)	)	-RRB-
cord-256444-grw5s2pf	28	17	OC43	OC43	NNP
cord-256444-grw5s2pf	28	18	and	and	CC
cord-256444-grw5s2pf	28	19	HCV	HCV	NNP
cord-256444-grw5s2pf	28	20	2293	2293	CD
cord-256444-grw5s2pf	28	21	,	,	,
cord-256444-grw5s2pf	28	22	both	both	DT
cord-256444-grw5s2pf	28	23	of	of	IN
cord-256444-grw5s2pf	28	24	which	which	WDT
cord-256444-grw5s2pf	28	25	are	be	VBP
cord-256444-grw5s2pf	28	26	a	a	DT
cord-256444-grw5s2pf	28	27	cause	cause	NN
cord-256444-grw5s2pf	28	28	of	of	IN
cord-256444-grw5s2pf	28	29	the	the	DT
cord-256444-grw5s2pf	28	30	common	common	JJ
cord-256444-grw5s2pf	28	31	cold	cold	NN
cord-256444-grw5s2pf	28	32	.	.	.
cord-256444-grw5s2pf	29	1	There	there	EX
cord-256444-grw5s2pf	29	2	is	be	VBZ
cord-256444-grw5s2pf	29	3	evidence	evidence	NN
cord-256444-grw5s2pf	29	4	for	for	IN
cord-256444-grw5s2pf	29	5	the	the	DT
cord-256444-grw5s2pf	29	6	presence	presence	NN
cord-256444-grw5s2pf	29	7	of	of	IN
cord-256444-grw5s2pf	29	8	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	29	9	in	in	IN
cord-256444-grw5s2pf	29	10	tissues	tissue	NNS
cord-256444-grw5s2pf	29	11	taken	take	VBN
cord-256444-grw5s2pf	29	12	from	from	IN
cord-256444-grw5s2pf	29	13	multiple	multiple	JJ
cord-256444-grw5s2pf	29	14	sclerosis	sclerosis	NN
cord-256444-grw5s2pf	29	15	(	(	-LRB-
cord-256444-grw5s2pf	29	16	MS	MS	NNP
cord-256444-grw5s2pf	29	17	)	)	-RRB-
cord-256444-grw5s2pf	29	18	patients	patient	NNS
cord-256444-grw5s2pf	29	19	(	(	-LRB-
cord-256444-grw5s2pf	29	20	reviewed	review	VBN
cord-256444-grw5s2pf	29	21	by	by	IN
cord-256444-grw5s2pf	29	22	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	29	23	and	and	CC
cord-256444-grw5s2pf	29	24	Macnaughton	Macnaughton	NNP
cord-256444-grw5s2pf	29	25	,	,	,
cord-256444-grw5s2pf	29	26	1995	1995	CD
cord-256444-grw5s2pf	29	27	)	)	-RRB-
cord-256444-grw5s2pf	29	28	.	.	.
cord-256444-grw5s2pf	30	1	This	this	DT
cord-256444-grw5s2pf	30	2	inflammatory	inflammatory	JJ
cord-256444-grw5s2pf	30	3	,	,	,
cord-256444-grw5s2pf	30	4	demyelinating	demyelinate	VBG
cord-256444-grw5s2pf	30	5	neurological	neurological	JJ
cord-256444-grw5s2pf	30	6	disease	disease	NN
cord-256444-grw5s2pf	30	7	is	be	VBZ
cord-256444-grw5s2pf	30	8	associated	associate	VBN
cord-256444-grw5s2pf	30	9	with	with	IN
cord-256444-grw5s2pf	30	10	autoreactive	autoreactive	JJ
cord-256444-grw5s2pf	30	11	T	t	NN
cord-256444-grw5s2pf	30	12	lymphocytes	lymphocyte	NNS
cord-256444-grw5s2pf	30	13	sensitized	sensitize	VBN
cord-256444-grw5s2pf	30	14	to	to	IN
cord-256444-grw5s2pf	30	15	myelin	myelin	JJ
cord-256444-grw5s2pf	30	16	components	component	NNS
cord-256444-grw5s2pf	30	17	of	of	IN
cord-256444-grw5s2pf	30	18	the	the	DT
cord-256444-grw5s2pf	30	19	central	central	JJ
cord-256444-grw5s2pf	30	20	nervous	nervous	JJ
cord-256444-grw5s2pf	30	21	system	system	NN
cord-256444-grw5s2pf	30	22	.	.	.
cord-256444-grw5s2pf	31	1	Recently	recently	RB
cord-256444-grw5s2pf	31	2	,	,	,
cord-256444-grw5s2pf	31	3	Talbot	Talbot	NNP
cord-256444-grw5s2pf	31	4	and	and	CC
cord-256444-grw5s2pf	31	5	colleagues	colleague	NNS
cord-256444-grw5s2pf	31	6	(	(	-LRB-
cord-256444-grw5s2pf	31	7	1996	1996	CD
cord-256444-grw5s2pf	31	8	)	)	-RRB-
cord-256444-grw5s2pf	31	9	have	have	VBP
cord-256444-grw5s2pf	31	10	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	31	11	that	that	IN
cord-256444-grw5s2pf	31	12	many	many	JJ
cord-256444-grw5s2pf	31	13	CD4	CD4	NNP
cord-256444-grw5s2pf	31	14	'	'	POS
cord-256444-grw5s2pf	31	15	T	t	NN
cord-256444-grw5s2pf	31	16	-	-	HYPH
cord-256444-grw5s2pf	31	17	cell	cell	NN
cord-256444-grw5s2pf	31	18	lines	line	NNS
cord-256444-grw5s2pf	31	19	derived	derive	VBN
cord-256444-grw5s2pf	31	20	from	from	IN
cord-256444-grw5s2pf	31	21	MS	MS	NNP
cord-256444-grw5s2pf	31	22	patients	patient	NNS
cord-256444-grw5s2pf	31	23	showed	show	VBD
cord-256444-grw5s2pf	31	24	a	a	DT
cord-256444-grw5s2pf	31	25	human	human	JJ
cord-256444-grw5s2pf	31	26	leukocyte	leukocyte	NN
cord-256444-grw5s2pf	31	27	antigen-(HLA)-DR	antigen-(HLA)-DR	NNS
cord-256444-grw5s2pf	31	28	-	-	,
cord-256444-grw5s2pf	31	29	restricted	restrict	VBN
cord-256444-grw5s2pf	31	30	,	,	,
cord-256444-grw5s2pf	31	31	crossreactive	crossreactive	JJ
cord-256444-grw5s2pf	31	32	pattern	pattern	NN
cord-256444-grw5s2pf	31	33	of	of	IN
cord-256444-grw5s2pf	31	34	antigen	antigen	NN
cord-256444-grw5s2pf	31	35	activation	activation	NN
cord-256444-grw5s2pf	31	36	after	after	IN
cord-256444-grw5s2pf	31	37	in	in	IN
cord-256444-grw5s2pf	31	38	vitro	vitro	FW
cord-256444-grw5s2pf	31	39	selection	selection	NN
cord-256444-grw5s2pf	31	40	of	of	IN
cord-256444-grw5s2pf	31	41	either	either	CC
cord-256444-grw5s2pf	31	42	myelin	myelin	JJ
cord-256444-grw5s2pf	31	43	basic	basic	JJ
cord-256444-grw5s2pf	31	44	protein	protein	NN
cord-256444-grw5s2pf	31	45	or	or	CC
cord-256444-grw5s2pf	31	46	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	31	47	proteins	protein	NNS
cord-256444-grw5s2pf	31	48	,	,	,
cord-256444-grw5s2pf	31	49	suggesting	suggest	VBG
cord-256444-grw5s2pf	31	50	that	that	IN
cord-256444-grw5s2pf	31	51	molecular	molecular	JJ
cord-256444-grw5s2pf	31	52	mimicry	mimicry	NN
cord-256444-grw5s2pf	31	53	between	between	IN
cord-256444-grw5s2pf	31	54	HCV	HCV	NNP
cord-256444-grw5s2pf	31	55	and	and	CC
cord-256444-grw5s2pf	31	56	myelin	myelin	NN
cord-256444-grw5s2pf	31	57	may	may	MD
cord-256444-grw5s2pf	31	58	be	be	VB
cord-256444-grw5s2pf	31	59	a	a	DT
cord-256444-grw5s2pf	31	60	n	n	NNP
cord-256444-grw5s2pf	31	61	immunopathological	immunopathological	JJ
cord-256444-grw5s2pf	31	62	mechanism	mechanism	NN
cord-256444-grw5s2pf	31	63	in	in	IN
cord-256444-grw5s2pf	31	64	MS	MS	NNP
cord-256444-grw5s2pf	31	65	.	.	.
cord-256444-grw5s2pf	32	1	Other	other	JJ
cord-256444-grw5s2pf	32	2	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	32	3	[	[	-LRB-
cord-256444-grw5s2pf	32	4	some	some	DT
cord-256444-grw5s2pf	32	5	strains	strain	NNS
cord-256444-grw5s2pf	32	6	of	of	IN
cord-256444-grw5s2pf	32	7	murine	murine	JJ
cord-256444-grw5s2pf	32	8	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	32	9	virus	virus	NN
cord-256444-grw5s2pf	32	10	(	(	-LRB-
cord-256444-grw5s2pf	32	11	MHV	MHV	NNP
cord-256444-grw5s2pf	32	12	)	)	-RRB-
cord-256444-grw5s2pf	32	13	and	and	CC
cord-256444-grw5s2pf	32	14	porcine	porcine	JJ
cord-256444-grw5s2pf	32	15	hemagglutinating	hemagglutinate	VBG
cord-256444-grw5s2pf	32	16	encephalomyelitis	encephalomyelitis	NN
cord-256444-grw5s2pf	32	17	virus	virus	NN
cord-256444-grw5s2pf	32	18	(	(	-LRB-
cord-256444-grw5s2pf	32	19	HEV	HEV	NNP
cord-256444-grw5s2pf	32	20	)	)	-RRB-
cord-256444-grw5s2pf	32	21	]	]	-RRB-
cord-256444-grw5s2pf	32	22	are	be	VBP
cord-256444-grw5s2pf	32	23	well	well	RB
cord-256444-grw5s2pf	32	24	-	-	HYPH
cord-256444-grw5s2pf	32	25	known	know	VBN
cord-256444-grw5s2pf	32	26	causes	cause	NNS
cord-256444-grw5s2pf	32	27	of	of	IN
cord-256444-grw5s2pf	32	28	neurological	neurological	JJ
cord-256444-grw5s2pf	32	29	diseases	disease	NNS
cord-256444-grw5s2pf	32	30	,	,	,
cord-256444-grw5s2pf	32	31	and	and	CC
cord-256444-grw5s2pf	32	32	MHV	MHV	NNP
cord-256444-grw5s2pf	32	33	has	have	VBZ
cord-256444-grw5s2pf	32	34	been	be	VBN
cord-256444-grw5s2pf	32	35	studied	study	VBN
cord-256444-grw5s2pf	32	36	for	for	IN
cord-256444-grw5s2pf	32	37	many	many	JJ
cord-256444-grw5s2pf	32	38	years	year	NNS
cord-256444-grw5s2pf	32	39	in	in	IN
cord-256444-grw5s2pf	32	40	this	this	DT
cord-256444-grw5s2pf	32	41	context	context	NN
cord-256444-grw5s2pf	32	42	(	(	-LRB-
cord-256444-grw5s2pf	32	43	Dales	Dales	NNP
cord-256444-grw5s2pf	32	44	and	and	CC
cord-256444-grw5s2pf	32	45	Anderson	Anderson	NNP
cord-256444-grw5s2pf	32	46	,	,	,
cord-256444-grw5s2pf	32	47	19951	19951	CD
cord-256444-grw5s2pf	32	48	,	,	,
cord-256444-grw5s2pf	32	49	although	although	IN
cord-256444-grw5s2pf	32	50	many	many	JJ
cord-256444-grw5s2pf	32	51	MHV	MHV	NNP
cord-256444-grw5s2pf	32	52	strains	strain	NNS
cord-256444-grw5s2pf	32	53	cause	cause	VBP
cord-256444-grw5s2pf	32	54	primarily	primarily	RB
cord-256444-grw5s2pf	32	55	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	32	56	.	.	.
cord-256444-grw5s2pf	33	1	The	the	DT
cord-256444-grw5s2pf	33	2	1970s	1970	NNS
cord-256444-grw5s2pf	33	3	and	and	CC
cord-256444-grw5s2pf	33	4	early	early	JJ
cord-256444-grw5s2pf	33	5	1980s	1980	NNS
cord-256444-grw5s2pf	33	6	was	be	VBD
cord-256444-grw5s2pf	33	7	the	the	DT
cord-256444-grw5s2pf	33	8	period	period	NN
cord-256444-grw5s2pf	33	9	in	in	IN
cord-256444-grw5s2pf	33	10	which	which	WDT
cord-256444-grw5s2pf	33	11	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	33	12	virion	virion	NN
cord-256444-grw5s2pf	33	13	proteins	protein	NNS
cord-256444-grw5s2pf	33	14	and	and	CC
cord-256444-grw5s2pf	33	15	nested	nest	VBN
cord-256444-grw5s2pf	33	16	-	-	HYPH
cord-256444-grw5s2pf	33	17	set	set	VBN
cord-256444-grw5s2pf	33	18	arrangements	arrangement	NNS
cord-256444-grw5s2pf	33	19	of	of	IN
cord-256444-grw5s2pf	33	20	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	33	21	were	be	VBD
cord-256444-grw5s2pf	33	22	identified	identify	VBN
cord-256444-grw5s2pf	33	23	and	and	CC
cord-256444-grw5s2pf	33	24	the	the	DT
cord-256444-grw5s2pf	33	25	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	33	26	nature	nature	NN
cord-256444-grw5s2pf	33	27	of	of	IN
cord-256444-grw5s2pf	33	28	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	33	29	transcription	transcription	NN
cord-256444-grw5s2pf	33	30	was	be	VBD
cord-256444-grw5s2pf	33	31	initially	initially	RB
cord-256444-grw5s2pf	33	32	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	33	33	.	.	.
cord-256444-grw5s2pf	34	1	The	the	DT
cord-256444-grw5s2pf	34	2	first	first	JJ
cord-256444-grw5s2pf	34	3	published	publish	VBN
cord-256444-grw5s2pf	34	4	sequence	sequence	NN
cord-256444-grw5s2pf	34	5	of	of	IN
cord-256444-grw5s2pf	34	6	a	a	DT
cord-256444-grw5s2pf	34	7	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	34	8	gene	gene	NN
cord-256444-grw5s2pf	34	9	appeared	appear	VBD
cord-256444-grw5s2pf	34	10	in	in	IN
cord-256444-grw5s2pf	34	11	1983	1983	CD
cord-256444-grw5s2pf	34	12	,	,	,
cord-256444-grw5s2pf	34	13	starting	start	VBG
cord-256444-grw5s2pf	34	14	an	an	DT
cord-256444-grw5s2pf	34	15	era	era	NN
cord-256444-grw5s2pf	34	16	in	in	IN
cord-256444-grw5s2pf	34	17	which	which	WDT
cord-256444-grw5s2pf	34	18	the	the	DT
cord-256444-grw5s2pf	34	19	whole	whole	NN
cord-256444-grw5s2pf	34	20	of	of	IN
cord-256444-grw5s2pf	34	21	the	the	DT
cord-256444-grw5s2pf	34	22	genomes	genome	NNS
cord-256444-grw5s2pf	34	23	of	of	IN
cord-256444-grw5s2pf	34	24	four	four	CD
cord-256444-grw5s2pf	34	25	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	34	26	were	be	VBD
cord-256444-grw5s2pf	34	27	clonedin	clonedin	NNS
cord-256444-grw5s2pf	34	28	piecesand	piecesand	NNP
cord-256444-grw5s2pf	34	29	sequenced	sequence	VBN
cord-256444-grw5s2pf	34	30	.	.	.
cord-256444-grw5s2pf	35	1	This	this	DT
cord-256444-grw5s2pf	35	2	decade	decade	NN
cord-256444-grw5s2pf	35	3	has	have	VBZ
cord-256444-grw5s2pf	35	4	seen	see	VBN
cord-256444-grw5s2pf	35	5	the	the	DT
cord-256444-grw5s2pf	35	6	manipulation	manipulation	NN
cord-256444-grw5s2pf	35	7	of	of	IN
cord-256444-grw5s2pf	35	8	these	these	DT
cord-256444-grw5s2pf	35	9	clones	clone	NNS
cord-256444-grw5s2pf	35	10	,	,	,
cord-256444-grw5s2pf	35	11	and	and	CC
cord-256444-grw5s2pf	35	12	of	of	IN
cord-256444-grw5s2pf	35	13	complementary	complementary	JJ
cord-256444-grw5s2pf	35	14	DNAs	dna	NNS
cord-256444-grw5s2pf	35	15	(	(	-LRB-
cord-256444-grw5s2pf	35	16	cDNAs	cDNAs	NNPS
cord-256444-grw5s2pf	35	17	)	)	-RRB-
cord-256444-grw5s2pf	35	18	of	of	IN
cord-256444-grw5s2pf	35	19	defective	defective	JJ
cord-256444-grw5s2pf	35	20	-	-	HYPH
cord-256444-grw5s2pf	35	21	interfering	interfere	VBG
cord-256444-grw5s2pf	35	22	(	(	-LRB-
cord-256444-grw5s2pf	35	23	DI	DI	NNP
cord-256444-grw5s2pf	35	24	)	)	-RRB-
cord-256444-grw5s2pf	35	25	RNAs	rna	NNS
cord-256444-grw5s2pf	35	26	,	,	,
cord-256444-grw5s2pf	35	27	to	to	TO
cord-256444-grw5s2pf	35	28	study	study	VB
cord-256444-grw5s2pf	35	29	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	35	30	RNA	RNA	NNP
cord-256444-grw5s2pf	35	31	replication	replication	NN
cord-256444-grw5s2pf	35	32	,	,	,
cord-256444-grw5s2pf	35	33	transcription	transcription	NN
cord-256444-grw5s2pf	35	34	,	,	,
cord-256444-grw5s2pf	35	35	recombination	recombination	NN
cord-256444-grw5s2pf	35	36	,	,	,
cord-256444-grw5s2pf	35	37	processing	processing	NN
cord-256444-grw5s2pf	35	38	and	and	CC
cord-256444-grw5s2pf	35	39	transport	transport	NN
cord-256444-grw5s2pf	35	40	of	of	IN
cord-256444-grw5s2pf	35	41	proteins	protein	NNS
cord-256444-grw5s2pf	35	42	,	,	,
cord-256444-grw5s2pf	35	43	virion	virion	NN
cord-256444-grw5s2pf	35	44	assembly	assembly	NN
cord-256444-grw5s2pf	35	45	,	,	,
cord-256444-grw5s2pf	35	46	identification	identification	NN
cord-256444-grw5s2pf	35	47	of	of	IN
cord-256444-grw5s2pf	35	48	cell	cell	NN
cord-256444-grw5s2pf	35	49	receptors	receptor	NNS
cord-256444-grw5s2pf	35	50	for	for	IN
cord-256444-grw5s2pf	35	51	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	35	52	,	,	,
cord-256444-grw5s2pf	35	53	and	and	CC
cord-256444-grw5s2pf	35	54	processing	processing	NN
cord-256444-grw5s2pf	35	55	of	of	IN
cord-256444-grw5s2pf	35	56	the	the	DT
cord-256444-grw5s2pf	35	57	polymerase	polymerase	NN
cord-256444-grw5s2pf	35	58	.	.	.
cord-256444-grw5s2pf	36	1	This	this	DT
cord-256444-grw5s2pf	36	2	review	review	NN
cord-256444-grw5s2pf	36	3	is	be	VBZ
cord-256444-grw5s2pf	36	4	largely	largely	RB
cord-256444-grw5s2pf	36	5	concerned	concerned	JJ
cord-256444-grw5s2pf	36	6	with	with	IN
cord-256444-grw5s2pf	36	7	these	these	DT
cord-256444-grw5s2pf	36	8	areas	area	NNS
cord-256444-grw5s2pf	36	9	.	.	.
cord-256444-grw5s2pf	37	1	Some	some	DT
cord-256444-grw5s2pf	37	2	topics	topic	NNS
cord-256444-grw5s2pf	37	3	are	be	VBP
cord-256444-grw5s2pf	37	4	notable	notable	JJ
cord-256444-grw5s2pf	37	5	by	by	IN
cord-256444-grw5s2pf	37	6	their	-PRON-	PRP$
cord-256444-grw5s2pf	37	7	absence	absence	NN
cord-256444-grw5s2pf	37	8	,	,	,
cord-256444-grw5s2pf	37	9	space	space	NN
cord-256444-grw5s2pf	37	10	not	not	RB
cord-256444-grw5s2pf	37	11	permitting	permit	VBG
cord-256444-grw5s2pf	37	12	their	-PRON-	PRP$
cord-256444-grw5s2pf	37	13	inclusion	inclusion	NN
cord-256444-grw5s2pf	37	14	.	.	.
cord-256444-grw5s2pf	38	1	For	for	IN
cord-256444-grw5s2pf	38	2	example	example	NN
cord-256444-grw5s2pf	38	3	,	,	,
cord-256444-grw5s2pf	38	4	the	the	DT
cord-256444-grw5s2pf	38	5	elucidation	elucidation	NN
cord-256444-grw5s2pf	38	6	of	of	IN
cord-256444-grw5s2pf	38	7	the	the	DT
cord-256444-grw5s2pf	38	8	molecular	molecular	JJ
cord-256444-grw5s2pf	38	9	basis	basis	NN
cord-256444-grw5s2pf	38	10	of	of	IN
cord-256444-grw5s2pf	38	11	the	the	DT
cord-256444-grw5s2pf	38	12	antigenic	antigenic	JJ
cord-256444-grw5s2pf	38	13	properties	property	NNS
cord-256444-grw5s2pf	38	14	of	of	IN
cord-256444-grw5s2pf	38	15	the	the	DT
cord-256444-grw5s2pf	38	16	large	large	JJ
cord-256444-grw5s2pf	38	17	surface	surface	NN
cord-256444-grw5s2pf	38	18	(	(	-LRB-
cord-256444-grw5s2pf	38	19	spike	spike	NN
cord-256444-grw5s2pf	38	20	)	)	-RRB-
cord-256444-grw5s2pf	38	21	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	38	22	and	and	CC
cord-256444-grw5s2pf	38	23	its	-PRON-	PRP$
cord-256444-grw5s2pf	38	24	role	role	NN
cord-256444-grw5s2pf	38	25	in	in	IN
cord-256444-grw5s2pf	38	26	tissue	tissue	NN
cord-256444-grw5s2pf	38	27	tropism	tropism	NN
cord-256444-grw5s2pf	38	28	has	have	VBZ
cord-256444-grw5s2pf	38	29	been	be	VBN
cord-256444-grw5s2pf	38	30	omitted	omit	VBN
cord-256444-grw5s2pf	38	31	.	.	.
cord-256444-grw5s2pf	39	1	For	for	IN
cord-256444-grw5s2pf	39	2	these	these	DT
cord-256444-grw5s2pf	39	3	topics	topic	NNS
cord-256444-grw5s2pf	39	4	and	and	CC
cord-256444-grw5s2pf	39	5	all	all	DT
cord-256444-grw5s2pf	39	6	others	other	NNS
cord-256444-grw5s2pf	39	7	both	both	DT
cord-256444-grw5s2pf	39	8	within	within	IN
cord-256444-grw5s2pf	39	9	and	and	CC
cord-256444-grw5s2pf	39	10	without	without	IN
cord-256444-grw5s2pf	39	11	the	the	DT
cord-256444-grw5s2pf	39	12	compass	compass	NN
cord-256444-grw5s2pf	39	13	of	of	IN
cord-256444-grw5s2pf	39	14	our	-PRON-	PRP$
cord-256444-grw5s2pf	39	15	review	review	NN
cord-256444-grw5s2pf	39	16	for	for	IN
cord-256444-grw5s2pf	39	17	which	which	WDT
cord-256444-grw5s2pf	39	18	a	a	DT
cord-256444-grw5s2pf	39	19	concurrently	concurrently	RB
cord-256444-grw5s2pf	39	20	comprehensive	comprehensive	JJ
cord-256444-grw5s2pf	39	21	and	and	CC
cord-256444-grw5s2pf	39	22	in	in	IN
cord-256444-grw5s2pf	39	23	-	-	HYPH
cord-256444-grw5s2pf	39	24	depth	depth	NN
cord-256444-grw5s2pf	39	25	treatise	treatise	NN
cord-256444-grw5s2pf	39	26	is	be	VBZ
cord-256444-grw5s2pf	39	27	desired	desire	VBN
cord-256444-grw5s2pf	39	28	,	,	,
cord-256444-grw5s2pf	39	29	the	the	DT
cord-256444-grw5s2pf	39	30	reader	reader	NN
cord-256444-grw5s2pf	39	31	is	be	VBZ
cord-256444-grw5s2pf	39	32	referred	refer	VBN
cord-256444-grw5s2pf	39	33	to	to	IN
cord-256444-grw5s2pf	39	34	the	the	DT
cord-256444-grw5s2pf	39	35	book	book	NN
cord-256444-grw5s2pf	39	36	edited	edit	VBN
cord-256444-grw5s2pf	39	37	by	by	IN
cord-256444-grw5s2pf	39	38	Siddell	Siddell	NNP
cord-256444-grw5s2pf	39	39	(	(	-LRB-
cord-256444-grw5s2pf	39	40	1995a	1995a	CD
cord-256444-grw5s2pf	39	41	)	)	-RRB-
cord-256444-grw5s2pf	39	42	.	.	.
cord-256444-grw5s2pf	40	1	Individual	individual	JJ
cord-256444-grw5s2pf	40	2	chapters	chapter	NNS
cord-256444-grw5s2pf	40	3	in	in	IN
cord-256444-grw5s2pf	40	4	that	that	DT
cord-256444-grw5s2pf	40	5	book	book	NN
cord-256444-grw5s2pf	40	6	will	will	MD
cord-256444-grw5s2pf	40	7	be	be	VB
cord-256444-grw5s2pf	40	8	referenced	reference	VBN
cord-256444-grw5s2pf	40	9	a	a	DT
cord-256444-grw5s2pf	40	10	t	t	NN
cord-256444-grw5s2pf	40	11	the	the	DT
cord-256444-grw5s2pf	40	12	appropriate	appropriate	JJ
cord-256444-grw5s2pf	40	13	places	place	NNS
cord-256444-grw5s2pf	40	14	in	in	IN
cord-256444-grw5s2pf	40	15	this	this	DT
cord-256444-grw5s2pf	40	16	review	review	NN
cord-256444-grw5s2pf	40	17	.	.	.
cord-256444-grw5s2pf	41	1	All	all	DT
cord-256444-grw5s2pf	41	2	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	41	3	belong	belong	VBP
cord-256444-grw5s2pf	41	4	to	to	IN
cord-256444-grw5s2pf	41	5	one	one	CD
cord-256444-grw5s2pf	41	6	genus	genus	NN
cord-256444-grw5s2pf	41	7	,	,	,
cord-256444-grw5s2pf	41	8	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	41	9	,	,	,
cord-256444-grw5s2pf	41	10	within	within	IN
cord-256444-grw5s2pf	41	11	the	the	DT
cord-256444-grw5s2pf	41	12	family	family	NN
cord-256444-grw5s2pf	41	13	Coronaviridae	Coronaviridae	NNP
cord-256444-grw5s2pf	41	14	.	.	.
cord-256444-grw5s2pf	42	1	Initially	initially	RB
cord-256444-grw5s2pf	42	2	,	,	,
cord-256444-grw5s2pf	42	3	serological	serological	JJ
cord-256444-grw5s2pf	42	4	analysis	analysis	NN
cord-256444-grw5s2pf	42	5	was	be	VBD
cord-256444-grw5s2pf	42	6	used	use	VBN
cord-256444-grw5s2pf	42	7	to	to	TO
cord-256444-grw5s2pf	42	8	differentiate	differentiate	VB
cord-256444-grw5s2pf	42	9	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	42	10	species	specie	NNS
cord-256444-grw5s2pf	42	11	and	and	CC
cord-256444-grw5s2pf	42	12	showed	show	VBD
cord-256444-grw5s2pf	42	13	that	that	IN
cord-256444-grw5s2pf	42	14	they	-PRON-	PRP
cord-256444-grw5s2pf	42	15	could	could	MD
cord-256444-grw5s2pf	42	16	be	be	VB
cord-256444-grw5s2pf	42	17	divided	divide	VBN
cord-256444-grw5s2pf	42	18	into	into	IN
cord-256444-grw5s2pf	42	19	four	four	CD
cord-256444-grw5s2pf	42	20	antigenic	antigenic	JJ
cord-256444-grw5s2pf	42	21	groups	group	NNS
cord-256444-grw5s2pf	42	22	(	(	-LRB-
cord-256444-grw5s2pf	42	23	Holmes	Holmes	NNP
cord-256444-grw5s2pf	42	24	,	,	,
cord-256444-grw5s2pf	42	25	1990	1990	CD
cord-256444-grw5s2pf	42	26	)	)	-RRB-
cord-256444-grw5s2pf	42	27	.	.	.
cord-256444-grw5s2pf	43	1	The	the	DT
cord-256444-grw5s2pf	43	2	species	specie	NNS
cord-256444-grw5s2pf	43	3	and	and	CC
cord-256444-grw5s2pf	43	4	group	group	NN
cord-256444-grw5s2pf	43	5	divisions	division	NNS
cord-256444-grw5s2pf	43	6	were	be	VBD
cord-256444-grw5s2pf	43	7	subsequently	subsequently	RB
cord-256444-grw5s2pf	43	8	refined	refine	VBN
cord-256444-grw5s2pf	43	9	by	by	IN
cord-256444-grw5s2pf	43	10	monoclonal	monoclonal	JJ
cord-256444-grw5s2pf	43	11	antibody	antibody	NN
cord-256444-grw5s2pf	43	12	analysis	analysis	NN
cord-256444-grw5s2pf	43	13	and	and	CC
cord-256444-grw5s2pf	43	14	nucleotide	nucleotide	JJ
cord-256444-grw5s2pf	43	15	sequencing	sequencing	NN
cord-256444-grw5s2pf	43	16	,	,	,
cord-256444-grw5s2pf	43	17	which	which	WDT
cord-256444-grw5s2pf	43	18	revealed	reveal	VBD
cord-256444-grw5s2pf	43	19	the	the	DT
cord-256444-grw5s2pf	43	20	close	close	JJ
cord-256444-grw5s2pf	43	21	relatedness	relatedness	NN
cord-256444-grw5s2pf	43	22	between	between	IN
cord-256444-grw5s2pf	43	23	TCV	TCV	NNP
cord-256444-grw5s2pf	43	24	and	and	CC
cord-256444-grw5s2pf	43	25	BCV	BCV	NNP
cord-256444-grw5s2pf	43	26	,	,	,
cord-256444-grw5s2pf	43	27	resulting	result	VBG
cord-256444-grw5s2pf	43	28	in	in	IN
cord-256444-grw5s2pf	43	29	the	the	DT
cord-256444-grw5s2pf	43	30	current	current	JJ
cord-256444-grw5s2pf	43	31	classification	classification	NN
cord-256444-grw5s2pf	43	32	of	of	IN
cord-256444-grw5s2pf	43	33	three	three	CD
cord-256444-grw5s2pf	43	34	antigenic	antigenic	JJ
cord-256444-grw5s2pf	43	35	groups	group	NNS
cord-256444-grw5s2pf	43	36	(	(	-LRB-
cord-256444-grw5s2pf	43	37	Table	table	NN
cord-256444-grw5s2pf	43	38	I	i	CD
cord-256444-grw5s2pf	43	39	)	)	-RRB-
cord-256444-grw5s2pf	43	40	.	.	.
cord-256444-grw5s2pf	44	1	The	the	DT
cord-256444-grw5s2pf	44	2	same	same	JJ
cord-256444-grw5s2pf	44	3	groupings	grouping	NNS
cord-256444-grw5s2pf	44	4	emerge	emerge	VBP
cord-256444-grw5s2pf	44	5	regardless	regardless	RB
cord-256444-grw5s2pf	44	6	of	of	IN
cord-256444-grw5s2pf	44	7	which	which	WDT
cord-256444-grw5s2pf	44	8	structural	structural	JJ
cord-256444-grw5s2pf	44	9	protein	protein	NN
cord-256444-grw5s2pf	44	10	sequences	sequence	NNS
cord-256444-grw5s2pf	44	11	are	be	VBP
cord-256444-grw5s2pf	44	12	compared	compare	VBN
cord-256444-grw5s2pf	44	13	(	(	-LRB-
cord-256444-grw5s2pf	44	14	Siddell	Siddell	NNP
cord-256444-grw5s2pf	44	15	,	,	,
cord-256444-grw5s2pf	44	16	1995b	1995b	CD
cord-256444-grw5s2pf	44	17	)	)	-RRB-
cord-256444-grw5s2pf	44	18	.	.	.
cord-256444-grw5s2pf	45	1	Within	within	IN
cord-256444-grw5s2pf	45	2	group	group	NN
cord-256444-grw5s2pf	45	3	1	1	CD
cord-256444-grw5s2pf	45	4	,	,	,
cord-256444-grw5s2pf	45	5	TGEV	TGEV	NNP
cord-256444-grw5s2pf	45	6	,	,	,
cord-256444-grw5s2pf	45	7	FCV	FCV	NNP
cord-256444-grw5s2pf	45	8	,	,	,
cord-256444-grw5s2pf	45	9	and	and	CC
cord-256444-grw5s2pf	45	10	CCV	CCV	NNP
cord-256444-grw5s2pf	45	11	are	be	VBP
cord-256444-grw5s2pf	45	12	particularly	particularly	RB
cord-256444-grw5s2pf	45	13	closely	closely	RB
cord-256444-grw5s2pf	45	14	related	related	JJ
cord-256444-grw5s2pf	45	15	,	,	,
cord-256444-grw5s2pf	45	16	all	all	PDT
cord-256444-grw5s2pf	45	17	the	the	DT
cord-256444-grw5s2pf	45	18	members	member	NNS
cord-256444-grw5s2pf	45	19	of	of	IN
cord-256444-grw5s2pf	45	20	group	group	NN
cord-256444-grw5s2pf	45	21	2	2	CD
cord-256444-grw5s2pf	45	22	being	be	VBG
cord-256444-grw5s2pf	45	23	tightly	tightly	RB
cord-256444-grw5s2pf	45	24	clustered	cluster	VBN
cord-256444-grw5s2pf	45	25	.	.	.
cord-256444-grw5s2pf	46	1	The	the	DT
cord-256444-grw5s2pf	46	2	sole	sole	JJ
cord-256444-grw5s2pf	46	3	member	member	NN
cord-256444-grw5s2pf	46	4	of	of	IN
cord-256444-grw5s2pf	46	5	group	group	NN
cord-256444-grw5s2pf	46	6	3	3	CD
cord-256444-grw5s2pf	46	7	,	,	,
cord-256444-grw5s2pf	46	8	IBV	IBV	NNP
cord-256444-grw5s2pf	46	9	,	,	,
cord-256444-grw5s2pf	46	10	not	not	RB
cord-256444-grw5s2pf	46	11	only	only	RB
cord-256444-grw5s2pf	46	12	differs	differ	VBZ
cord-256444-grw5s2pf	46	13	extensively	extensively	RB
cord-256444-grw5s2pf	46	14	from	from	IN
cord-256444-grw5s2pf	46	15	all	all	DT
cord-256444-grw5s2pf	46	16	other	other	JJ
cord-256444-grw5s2pf	46	17	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	46	18	but	but	CC
cord-256444-grw5s2pf	46	19	also	also	RB
cord-256444-grw5s2pf	46	20	exhibits	exhibit	VBZ
cord-256444-grw5s2pf	46	21	extensive	extensive	JJ
cord-256444-grw5s2pf	46	22	variation	variation	NN
cord-256444-grw5s2pf	46	23	within	within	IN
cord-256444-grw5s2pf	46	24	the	the	DT
cord-256444-grw5s2pf	46	25	species	specie	NNS
cord-256444-grw5s2pf	46	26	.	.	.
cord-256444-grw5s2pf	47	1	The	the	DT
cord-256444-grw5s2pf	47	2	Coronaviridae	Coronaviridae	NNP
cord-256444-grw5s2pf	47	3	had	have	VBD
cord-256444-grw5s2pf	47	4	remained	remain	VBN
cord-256444-grw5s2pf	47	5	a	a	DT
cord-256444-grw5s2pf	47	6	monogeneric	monogeneric	JJ
cord-256444-grw5s2pf	47	7	family	family	NN
cord-256444-grw5s2pf	47	8	for	for	IN
cord-256444-grw5s2pf	47	9	a	a	DT
cord-256444-grw5s2pf	47	10	quarter	quarter	NN
cord-256444-grw5s2pf	47	11	of	of	IN
cord-256444-grw5s2pf	47	12	a	a	DT
cord-256444-grw5s2pf	47	13	century	century	NN
cord-256444-grw5s2pf	47	14	,	,	,
cord-256444-grw5s2pf	47	15	until	until	IN
cord-256444-grw5s2pf	47	16	an	an	DT
cord-256444-grw5s2pf	47	17	accumulation	accumulation	NN
cord-256444-grw5s2pf	47	18	of	of	IN
cord-256444-grw5s2pf	47	19	observations	observation	NNS
cord-256444-grw5s2pf	47	20	which	which	WDT
cord-256444-grw5s2pf	47	21	showed	show	VBD
cord-256444-grw5s2pf	47	22	that	that	IN
cord-256444-grw5s2pf	47	23	many	many	JJ
cord-256444-grw5s2pf	47	24	of	of	IN
cord-256444-grw5s2pf	47	25	the	the	DT
cord-256444-grw5s2pf	47	26	features	feature	NNS
cord-256444-grw5s2pf	47	27	thought	think	VBN
cord-256444-grw5s2pf	47	28	to	to	TO
cord-256444-grw5s2pf	47	29	be	be	VB
cord-256444-grw5s2pf	47	30	characteristic	characteristic	JJ
cord-256444-grw5s2pf	47	31	of	of	IN
cord-256444-grw5s2pf	47	32	the	the	DT
cord-256444-grw5s2pf	47	33	Coronaviridae	Coronaviridae	NNP
cord-256444-grw5s2pf	47	34	applied	apply	VBD
cord-256444-grw5s2pf	47	35	equally	equally	RB
cord-256444-grw5s2pf	47	36	well	well	RB
cord-256444-grw5s2pf	47	37	to	to	IN
cord-256444-grw5s2pf	47	38	the	the	DT
cord-256444-grw5s2pf	47	39	genus	genus	NN
cord-256444-grw5s2pf	47	40	Torovirus	Torovirus	NNP
cord-256444-grw5s2pf	47	41	,	,	,
cord-256444-grw5s2pf	47	42	which	which	WDT
cord-256444-grw5s2pf	47	43	had	have	VBD
cord-256444-grw5s2pf	47	44	not	not	RB
cord-256444-grw5s2pf	47	45	been	be	VBN
cord-256444-grw5s2pf	47	46	officially	officially	RB
cord-256444-grw5s2pf	47	47	assigned	assign	VBN
cord-256444-grw5s2pf	47	48	to	to	IN
cord-256444-grw5s2pf	47	49	a	a	DT
cord-256444-grw5s2pf	47	50	family	family	NN
cord-256444-grw5s2pf	47	51	(	(	-LRB-
cord-256444-grw5s2pf	47	52	Figs	fig	NNS
cord-256444-grw5s2pf	47	53	.	.	.
cord-256444-grw5s2pf	48	1	1	1	CD
cord-256444-grw5s2pf	48	2	and	and	CC
cord-256444-grw5s2pf	48	3	2	2	CD
cord-256444-grw5s2pf	48	4	,	,	,
cord-256444-grw5s2pf	48	5	Table	table	NN
cord-256444-grw5s2pf	48	6	11	11	CD
cord-256444-grw5s2pf	48	7	)	)	-RRB-
cord-256444-grw5s2pf	48	8	.	.	.
cord-256444-grw5s2pf	49	1	Therefore	therefore	RB
cord-256444-grw5s2pf	49	2	,	,	,
cord-256444-grw5s2pf	49	3	in	in	IN
cord-256444-grw5s2pf	49	4	1993	1993	CD
cord-256444-grw5s2pf	49	5	,	,	,
cord-256444-grw5s2pf	49	6	the	the	DT
cord-256444-grw5s2pf	49	7	International	International	NNP
cord-256444-grw5s2pf	49	8	Committee	Committee	NNP
cord-256444-grw5s2pf	49	9	for	for	IN
cord-256444-grw5s2pf	49	10	the	the	DT
cord-256444-grw5s2pf	49	11	Taxonomy	Taxonomy	NNP
cord-256444-grw5s2pf	49	12	of	of	IN
cord-256444-grw5s2pf	49	13	Viruses	Viruses	NNPS
cord-256444-grw5s2pf	49	14	(	(	-LRB-
cord-256444-grw5s2pf	49	15	ICTV	ICTV	NNP
cord-256444-grw5s2pf	49	16	)	)	-RRB-
cord-256444-grw5s2pf	49	17	formally	formally	RB
cord-256444-grw5s2pf	49	18	expanded	expand	VBD
cord-256444-grw5s2pf	49	19	the	the	DT
cord-256444-grw5s2pf	49	20	Coronaviridae	Coronaviridae	NNP
cord-256444-grw5s2pf	49	21	to	to	TO
cord-256444-grw5s2pf	49	22	include	include	VB
cord-256444-grw5s2pf	49	23	Torovirus	Torovirus	NNP
cord-256444-grw5s2pf	49	24	.	.	.
cord-256444-grw5s2pf	50	1	The	the	DT
cord-256444-grw5s2pf	50	2	bringing	bring	VBG
cord-256444-grw5s2pf	50	3	together	together	RB
cord-256444-grw5s2pf	50	4	of	of	IN
cord-256444-grw5s2pf	50	5	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	50	6	and	and	CC
cord-256444-grw5s2pf	50	7	Torovirus	Torovirus	NNP
cord-256444-grw5s2pf	50	8	was	be	VBD
cord-256444-grw5s2pf	50	9	not	not	RB
cord-256444-grw5s2pf	50	10	the	the	DT
cord-256444-grw5s2pf	50	11	end	end	NN
cord-256444-grw5s2pf	50	12	of	of	IN
cord-256444-grw5s2pf	50	13	the	the	DT
cord-256444-grw5s2pf	50	14	taxonomic	taxonomic	JJ
cord-256444-grw5s2pf	50	15	story	story	NN
cord-256444-grw5s2pf	50	16	;	;	:
cord-256444-grw5s2pf	50	17	another	another	DT
cord-256444-grw5s2pf	50	18	family	family	NN
cord-256444-grw5s2pf	50	19	,	,	,
cord-256444-grw5s2pf	50	20	Arteriviridae	Arteriviridae	NNP
cord-256444-grw5s2pf	50	21	,	,	,
cord-256444-grw5s2pf	50	22	shared	share	VBD
cord-256444-grw5s2pf	50	23	important	important	JJ
cord-256444-grw5s2pf	50	24	characteristics	characteristic	NNS
cord-256444-grw5s2pf	50	25	in	in	IN
cord-256444-grw5s2pf	50	26	relation	relation	NN
cord-256444-grw5s2pf	50	27	to	to	IN
cord-256444-grw5s2pf	50	28	the	the	DT
cord-256444-grw5s2pf	50	29	genome	genome	NN
cord-256444-grw5s2pf	50	30	,	,	,
cord-256444-grw5s2pf	50	31	structure	structure	NN
cord-256444-grw5s2pf	50	32	,	,	,
cord-256444-grw5s2pf	50	33	and	and	CC
cord-256444-grw5s2pf	50	34	strategies	strategy	NNS
cord-256444-grw5s2pf	50	35	of	of	IN
cord-256444-grw5s2pf	50	36	transcription	transcription	NN
cord-256444-grw5s2pf	50	37	and	and	CC
cord-256444-grw5s2pf	50	38	translation	translation	NN
cord-256444-grw5s2pf	50	39	(	(	-LRB-
cord-256444-grw5s2pf	50	40	Table	table	NN
cord-256444-grw5s2pf	50	41	I1	i1	NN
cord-256444-grw5s2pf	50	42	)	)	-RRB-
cord-256444-grw5s2pf	51	1	(	(	-LRB-
cord-256444-grw5s2pf	51	2	Plagemann	Plagemann	NNP
cord-256444-grw5s2pf	51	3	and	and	CC
cord-256444-grw5s2pf	51	4	Moennig	Moennig	NNP
cord-256444-grw5s2pf	51	5	,	,	,
cord-256444-grw5s2pf	51	6	1992	1992	CD
cord-256444-grw5s2pf	51	7	;	;	:
cord-256444-grw5s2pf	51	8	Snijder	Snijder	NNP
cord-256444-grw5s2pf	51	9	and	and	CC
cord-256444-grw5s2pf	51	10	Spaan	Spaan	NNP
cord-256444-grw5s2pf	51	11	,	,	,
cord-256444-grw5s2pf	51	12	1995	1995	CD
cord-256444-grw5s2pf	51	13	)	)	-RRB-
cord-256444-grw5s2pf	51	14	.	.	.
cord-256444-grw5s2pf	52	1	However	however	RB
cord-256444-grw5s2pf	52	2	,	,	,
cord-256444-grw5s2pf	52	3	the	the	DT
cord-256444-grw5s2pf	52	4	distinct	distinct	JJ
cord-256444-grw5s2pf	52	5	morphology	morphology	NN
cord-256444-grw5s2pf	52	6	of	of	IN
cord-256444-grw5s2pf	52	7	the	the	DT
cord-256444-grw5s2pf	52	8	arteriviruses	arteriviruse	NNS
cord-256444-grw5s2pf	52	9	(	(	-LRB-
cord-256444-grw5s2pf	52	10	Fig	Fig	NNP
cord-256444-grw5s2pf	52	11	.	.	NNP
cord-256444-grw5s2pf	52	12	11	11	CD
cord-256444-grw5s2pf	52	13	,	,	,
cord-256444-grw5s2pf	52	14	and	and	CC
cord-256444-grw5s2pf	52	15	their	-PRON-	PRP$
cord-256444-grw5s2pf	52	16	underlying	underlying	JJ
cord-256444-grw5s2pf	52	17	differences	difference	NNS
cord-256444-grw5s2pf	52	18	from	from	IN
cord-256444-grw5s2pf	52	19	the	the	DT
cord-256444-grw5s2pf	52	20	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	52	21	in	in	IN
cord-256444-grw5s2pf	52	22	the	the	DT
cord-256444-grw5s2pf	52	23	size	size	NN
cord-256444-grw5s2pf	52	24	of	of	IN
cord-256444-grw5s2pf	52	25	the	the	DT
cord-256444-grw5s2pf	52	26	genome	genome	NN
cord-256444-grw5s2pf	52	27	(	(	-LRB-
cord-256444-grw5s2pf	52	28	Fig	Fig	NNP
cord-256444-grw5s2pf	52	29	.	.	NNP
cord-256444-grw5s2pf	52	30	2	2	CD
cord-256444-grw5s2pf	52	31	)	)	-RRB-
cord-256444-grw5s2pf	52	32	and	and	CC
cord-256444-grw5s2pf	52	33	structural	structural	JJ
cord-256444-grw5s2pf	52	34	proteins	protein	NNS
cord-256444-grw5s2pf	52	35	(	(	-LRB-
cord-256444-grw5s2pf	52	36	Table	Table	NNP
cord-256444-grw5s2pf	52	37	II	II	NNP
cord-256444-grw5s2pf	52	38	)	)	-RRB-
cord-256444-grw5s2pf	52	39	,	,	,
cord-256444-grw5s2pf	52	40	precluded	preclude	VBD
cord-256444-grw5s2pf	52	41	their	-PRON-	PRP$
cord-256444-grw5s2pf	52	42	inclusion	inclusion	NN
cord-256444-grw5s2pf	52	43	in	in	IN
cord-256444-grw5s2pf	52	44	the	the	DT
cord-256444-grw5s2pf	52	45	Coronaviridae	Coronaviridae	NNP
cord-256444-grw5s2pf	52	46	.	.	.
cord-256444-grw5s2pf	53	1	The	the	DT
cord-256444-grw5s2pf	53	2	common	common	JJ
cord-256444-grw5s2pf	53	3	features	feature	NNS
cord-256444-grw5s2pf	53	4	uniting	unite	VBG
cord-256444-grw5s2pf	53	5	the	the	DT
cord-256444-grw5s2pf	53	6	two	two	CD
cord-256444-grw5s2pf	53	7	families	family	NNS
cord-256444-grw5s2pf	53	8	(	(	-LRB-
cord-256444-grw5s2pf	53	9	Table	table	NN
cord-256444-grw5s2pf	53	10	11	11	CD
cord-256444-grw5s2pf	53	11	)	)	-RRB-
cord-256444-grw5s2pf	53	12	are	be	VBP
cord-256444-grw5s2pf	53	13	at	at	IN
cord-256444-grw5s2pf	53	14	the	the	DT
cord-256444-grw5s2pf	53	15	heart	heart	NN
cord-256444-grw5s2pf	53	16	of	of	IN
cord-256444-grw5s2pf	53	17	a	a	DT
cord-256444-grw5s2pf	53	18	proposal	proposal	NN
cord-256444-grw5s2pf	53	19	that	that	IN
cord-256444-grw5s2pf	53	20	an	an	DT
cord-256444-grw5s2pf	53	21	order	order	NN
cord-256444-grw5s2pf	53	22	be	be	VB
cord-256444-grw5s2pf	53	23	created	create	VBN
cord-256444-grw5s2pf	53	24	to	to	TO
cord-256444-grw5s2pf	53	25	contain	contain	VB
cord-256444-grw5s2pf	53	26	Coronaviridae	Coronaviridae	NNP
cord-256444-grw5s2pf	53	27	and	and	CC
cord-256444-grw5s2pf	53	28	Arteriviridae	Arteriviridae	NNP
cord-256444-grw5s2pf	53	29	to	to	TO
cord-256444-grw5s2pf	53	30	reflect	reflect	VB
cord-256444-grw5s2pf	53	31	their	-PRON-	PRP$
cord-256444-grw5s2pf	53	32	common	common	JJ
cord-256444-grw5s2pf	53	33	features	feature	NNS
cord-256444-grw5s2pf	53	34	and	and	CC
cord-256444-grw5s2pf	53	35	,	,	,
cord-256444-grw5s2pf	53	36	probably	probably	RB
cord-256444-grw5s2pf	53	37	,	,	,
cord-256444-grw5s2pf	53	38	their	-PRON-	PRP$
cord-256444-grw5s2pf	53	39	evolutionary	evolutionary	JJ
cord-256444-grw5s2pf	53	40	relationships	relationship	NNS
cord-256444-grw5s2pf	53	41	.	.	.
cord-256444-grw5s2pf	54	1	The	the	DT
cord-256444-grw5s2pf	54	2	name	name	NN
cord-256444-grw5s2pf	54	3	Nidovirales	Nidovirales	NNP
cord-256444-grw5s2pf	54	4	,	,	,
cord-256444-grw5s2pf	54	5	from	from	IN
cord-256444-grw5s2pf	54	6	the	the	DT
cord-256444-grw5s2pf	54	7	Latin	latin	JJ
cord-256444-grw5s2pf	54	8	nidus	nidus	NN
cord-256444-grw5s2pf	54	9	,	,	,
cord-256444-grw5s2pf	54	10	meaning	mean	VBG
cord-256444-grw5s2pf	54	11	nest	nest	NN
cord-256444-grw5s2pf	54	12	,	,	,
cord-256444-grw5s2pf	54	13	has	have	VBZ
cord-256444-grw5s2pf	54	14	been	be	VBN
cord-256444-grw5s2pf	54	15	designated	designate	VBN
cord-256444-grw5s2pf	54	16	for	for	IN
cord-256444-grw5s2pf	54	17	the	the	DT
cord-256444-grw5s2pf	54	18	order	order	NN
cord-256444-grw5s2pf	54	19	,	,	,
cord-256444-grw5s2pf	54	20	as	as	IN
cord-256444-grw5s2pf	54	21	all	all	DT
cord-256444-grw5s2pf	54	22	members	member	NNS
cord-256444-grw5s2pf	54	23	produce	produce	VBP
cord-256444-grw5s2pf	54	24	mRNAs	mrnas	CD
cord-256444-grw5s2pf	54	25	in	in	IN
cord-256444-grw5s2pf	54	26	an	an	DT
cord-256444-grw5s2pf	54	27	extensive	extensive	JJ
cord-256444-grw5s2pf	54	28	nested	nest	VBN
cord-256444-grw5s2pf	54	29	-	-	HYPH
cord-256444-grw5s2pf	54	30	set	set	NN
cord-256444-grw5s2pf	54	31	arrangement	arrangement	NN
cord-256444-grw5s2pf	54	32	.	.	.
cord-256444-grw5s2pf	55	1	The	the	DT
cord-256444-grw5s2pf	55	2	remainder	remainder	NN
cord-256444-grw5s2pf	55	3	of	of	IN
cord-256444-grw5s2pf	55	4	this	this	DT
cord-256444-grw5s2pf	55	5	review	review	NN
cord-256444-grw5s2pf	55	6	is	be	VBZ
cord-256444-grw5s2pf	55	7	restricted	restrict	VBN
cord-256444-grw5s2pf	55	8	largely	largely	RB
cord-256444-grw5s2pf	55	9	to	to	IN
cord-256444-grw5s2pf	55	10	the	the	DT
cord-256444-grw5s2pf	55	11	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	55	12	.	.	.
cord-256444-grw5s2pf	56	1	Coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	56	2	are	be	VBP
cord-256444-grw5s2pf	56	3	enveloped	envelop	VBN
cord-256444-grw5s2pf	56	4	,	,	,
cord-256444-grw5s2pf	56	5	more	more	JJR
cord-256444-grw5s2pf	56	6	or	or	CC
cord-256444-grw5s2pf	56	7	less	less	RBR
cord-256444-grw5s2pf	56	8	spherical	spherical	JJ
cord-256444-grw5s2pf	56	9	,	,	,
cord-256444-grw5s2pf	56	10	approximately	approximately	RB
cord-256444-grw5s2pf	56	11	120	120	CD
cord-256444-grw5s2pf	56	12	nm	nm	NN
cord-256444-grw5s2pf	56	13	in	in	IN
cord-256444-grw5s2pf	56	14	diameter	diameter	NN
cord-256444-grw5s2pf	56	15	,	,	,
cord-256444-grw5s2pf	56	16	with	with	IN
cord-256444-grw5s2pf	56	17	a	a	DT
cord-256444-grw5s2pf	56	18	prominent	prominent	JJ
cord-256444-grw5s2pf	56	19	fringe	fringe	NN
cord-256444-grw5s2pf	56	20	of	of	IN
cord-256444-grw5s2pf	56	21	20-nm	20-nm	CD
cord-256444-grw5s2pf	56	22	-	-	HYPH
cord-256444-grw5s2pf	56	23	long1	long1	VBN
cord-256444-grw5s2pf	56	24	petalshaped	petalshaped	NNP
cord-256444-grw5s2pf	56	25	surface	surface	NN
cord-256444-grw5s2pf	56	26	projections	projection	NNS
cord-256444-grw5s2pf	56	27	(	(	-LRB-
cord-256444-grw5s2pf	56	28	spikes	spike	NNS
cord-256444-grw5s2pf	56	29	)	)	-RRB-
cord-256444-grw5s2pf	56	30	composed	compose	VBN
cord-256444-grw5s2pf	56	31	of	of	IN
cord-256444-grw5s2pf	56	32	a	a	DT
cord-256444-grw5s2pf	56	33	heavily	heavily	RB
cord-256444-grw5s2pf	56	34	glycosylated	glycosylated	JJ
cord-256444-grw5s2pf	56	35	type	type	NN
cord-256444-grw5s2pf	56	36	I	-PRON-	PRP
cord-256444-grw5s2pf	56	37	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	56	38	,	,	,
cord-256444-grw5s2pf	56	39	spike	spike	NN
cord-256444-grw5s2pf	56	40	protein	protein	NN
cord-256444-grw5s2pf	56	41	(	(	-LRB-
cord-256444-grw5s2pf	56	42	S	s	NN
cord-256444-grw5s2pf	56	43	)	)	-RRB-
cord-256444-grw5s2pf	56	44	(	(	-LRB-
cord-256444-grw5s2pf	56	45	Fig	Fig	NNP
cord-256444-grw5s2pf	56	46	.	.	NNP
cord-256444-grw5s2pf	56	47	1	1	CD
cord-256444-grw5s2pf	56	48	)	)	-RRB-
cord-256444-grw5s2pf	56	49	.	.	.
cord-256444-grw5s2pf	57	1	A	a	DT
cord-256444-grw5s2pf	57	2	subset	subset	NN
cord-256444-grw5s2pf	57	3	of	of	IN
cord-256444-grw5s2pf	57	4	the	the	DT
cord-256444-grw5s2pf	57	5	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	57	6	(	(	-LRB-
cord-256444-grw5s2pf	57	7	Table	table	NN
cord-256444-grw5s2pf	57	8	I	-PRON-	PRP
cord-256444-grw5s2pf	57	9	)	)	-RRB-
cord-256444-grw5s2pf	57	10	has	have	VBZ
cord-256444-grw5s2pf	57	11	an	an	DT
cord-256444-grw5s2pf	57	12	additional	additional	JJ
cord-256444-grw5s2pf	57	13	layer	layer	NN
cord-256444-grw5s2pf	57	14	of	of	IN
cord-256444-grw5s2pf	57	15	short	short	JJ
cord-256444-grw5s2pf	57	16	spikes	spike	NNS
cord-256444-grw5s2pf	57	17	(	(	-LRB-
cord-256444-grw5s2pf	57	18	Caul	Caul	NNP
cord-256444-grw5s2pf	57	19	and	and	CC
cord-256444-grw5s2pf	57	20	Egglestone	Egglestone	NNP
cord-256444-grw5s2pf	57	21	,	,	,
cord-256444-grw5s2pf	57	22	1977	1977	CD
cord-256444-grw5s2pf	57	23	;	;	:
cord-256444-grw5s2pf	57	24	Dea	Dea	NNP
cord-256444-grw5s2pf	57	25	and	and	CC
cord-256444-grw5s2pf	57	26	Tijssen	Tijssen	NNP
cord-256444-grw5s2pf	57	27	,	,	,
cord-256444-grw5s2pf	57	28	1988	1988	CD
cord-256444-grw5s2pf	57	29	)	)	-RRB-
cord-256444-grw5s2pf	57	30	,	,	,
cord-256444-grw5s2pf	57	31	which	which	WDT
cord-256444-grw5s2pf	57	32	consist	consist	VBP
cord-256444-grw5s2pf	57	33	of	of	IN
cord-256444-grw5s2pf	57	34	hemagglutininesterase	hemagglutininesterase	NN
cord-256444-grw5s2pf	57	35	(	(	-LRB-
cord-256444-grw5s2pf	57	36	HE	HE	NNP
cord-256444-grw5s2pf	57	37	)	)	-RRB-
cord-256444-grw5s2pf	57	38	protein	protein	NN
cord-256444-grw5s2pf	57	39	,	,	,
cord-256444-grw5s2pf	57	40	also	also	RB
cord-256444-grw5s2pf	57	41	a	a	DT
cord-256444-grw5s2pf	57	42	type	type	NN
cord-256444-grw5s2pf	57	43	I	-PRON-	PRP
cord-256444-grw5s2pf	57	44	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	57	45	.	.	.
cord-256444-grw5s2pf	58	1	These	these	DT
cord-256444-grw5s2pf	58	2	small	small	JJ
cord-256444-grw5s2pf	58	3	spikes	spike	NNS
cord-256444-grw5s2pf	58	4	are	be	VBP
cord-256444-grw5s2pf	58	5	not	not	RB
cord-256444-grw5s2pf	58	6	essential	essential	JJ
cord-256444-grw5s2pf	58	7	for	for	IN
cord-256444-grw5s2pf	58	8	viral	viral	JJ
cord-256444-grw5s2pf	58	9	infectivity	infectivity	NN
cord-256444-grw5s2pf	58	10	.	.	.
cord-256444-grw5s2pf	59	1	Both	both	DT
cord-256444-grw5s2pf	59	2	the	the	DT
cord-256444-grw5s2pf	59	3	large	large	JJ
cord-256444-grw5s2pf	59	4	and	and	CC
cord-256444-grw5s2pf	59	5	small	small	JJ
cord-256444-grw5s2pf	59	6	spikes	spike	NNS
cord-256444-grw5s2pf	59	7	are	be	VBP
cord-256444-grw5s2pf	59	8	anchored	anchor	VBN
cord-256444-grw5s2pf	59	9	in	in	IN
cord-256444-grw5s2pf	59	10	the	the	DT
cord-256444-grw5s2pf	59	11	envelope	envelope	NN
cord-256444-grw5s2pf	59	12	,	,	,
cord-256444-grw5s2pf	59	13	which	which	WDT
cord-256444-grw5s2pf	59	14	is	be	VBZ
cord-256444-grw5s2pf	59	15	a	a	DT
cord-256444-grw5s2pf	59	16	lipid	lipid	NN
cord-256444-grw5s2pf	59	17	bilayer	bilayer	NN
cord-256444-grw5s2pf	59	18	formed	form	VBN
cord-256444-grw5s2pf	59	19	by	by	IN
cord-256444-grw5s2pf	59	20	virus	virus	NN
cord-256444-grw5s2pf	59	21	budding	bud	VBG
cord-256444-grw5s2pf	59	22	from	from	IN
cord-256444-grw5s2pf	59	23	intracellular	intracellular	JJ
cord-256444-grw5s2pf	59	24	membranes	membrane	NNS
cord-256444-grw5s2pf	59	25	.	.	.
cord-256444-grw5s2pf	60	1	The	the	DT
cord-256444-grw5s2pf	60	2	envelope	envelope	NN
cord-256444-grw5s2pf	60	3	is	be	VBZ
cord-256444-grw5s2pf	60	4	associated	associate	VBN
cord-256444-grw5s2pf	60	5	with	with	IN
cord-256444-grw5s2pf	60	6	,	,	,
cord-256444-grw5s2pf	60	7	in	in	IN
cord-256444-grw5s2pf	60	8	addition	addition	NN
cord-256444-grw5s2pf	60	9	to	to	IN
cord-256444-grw5s2pf	60	10	the	the	DT
cord-256444-grw5s2pf	60	11	S	S	NNP
cord-256444-grw5s2pf	60	12	and	and	CC
cord-256444-grw5s2pf	60	13	HE	HE	NNP
cord-256444-grw5s2pf	60	14	proteins	protein	VBZ
cord-256444-grw5s2pf	60	15	,	,	,
cord-256444-grw5s2pf	60	16	a	a	DT
cord-256444-grw5s2pf	60	17	smaller	small	JJR
cord-256444-grw5s2pf	60	18	type	type	NN
cord-256444-grw5s2pf	60	19	I11	I11	NNP
cord-256444-grw5s2pf	60	20	integral	integral	JJ
cord-256444-grw5s2pf	60	21	membrane	membrane	NN
cord-256444-grw5s2pf	60	22	protein	protein	NN
cord-256444-grw5s2pf	60	23	(	(	-LRB-
cord-256444-grw5s2pf	60	24	M	M	NNP
cord-256444-grw5s2pf	60	25	)	)	-RRB-
cord-256444-grw5s2pf	60	26	,	,	,
cord-256444-grw5s2pf	60	27	which	which	WDT
cord-256444-grw5s2pf	60	28	spans	span	VBZ
cord-256444-grw5s2pf	60	29	the	the	DT
cord-256444-grw5s2pf	60	30	envelope	envelope	NN
cord-256444-grw5s2pf	60	31	three	three	CD
cord-256444-grw5s2pf	60	32	times	time	NNS
cord-256444-grw5s2pf	60	33	.	.	.
cord-256444-grw5s2pf	61	1	An	an	DT
cord-256444-grw5s2pf	61	2	even	even	RB
cord-256444-grw5s2pf	61	3	smaller	small	JJR
cord-256444-grw5s2pf	61	4	protein	protein	NN
cord-256444-grw5s2pf	61	5	[	[	-LRB-
cord-256444-grw5s2pf	61	6	envelope	envelope	NN
cord-256444-grw5s2pf	61	7	(	(	-LRB-
cord-256444-grw5s2pf	61	8	E	e	NN
cord-256444-grw5s2pf	61	9	)	)	-RRB-
cord-256444-grw5s2pf	61	10	or	or	CC
cord-256444-grw5s2pf	61	11	small	small	JJ
cord-256444-grw5s2pf	61	12	membrane	membrane	NN
cord-256444-grw5s2pf	61	13	(	(	-LRB-
cord-256444-grw5s2pf	61	14	sM	sm	NN
cord-256444-grw5s2pf	61	15	)	)	-RRB-
cord-256444-grw5s2pf	61	16	protein	protein	NN
cord-256444-grw5s2pf	61	17	]	]	-RRB-
cord-256444-grw5s2pf	61	18	has	have	VBZ
cord-256444-grw5s2pf	61	19	recently	recently	RB
cord-256444-grw5s2pf	61	20	been	be	VBN
cord-256444-grw5s2pf	61	21	shown	show	VBN
cord-256444-grw5s2pf	61	22	to	to	TO
cord-256444-grw5s2pf	61	23	be	be	VB
cord-256444-grw5s2pf	61	24	an	an	DT
cord-256444-grw5s2pf	61	25	integral	integral	JJ
cord-256444-grw5s2pf	61	26	membrane	membrane	NN
cord-256444-grw5s2pf	61	27	protein	protein	NN
cord-256444-grw5s2pf	61	28	of	of	IN
cord-256444-grw5s2pf	61	29	the	the	DT
cord-256444-grw5s2pf	61	30	viral	viral	JJ
cord-256444-grw5s2pf	61	31	envelope	envelope	NN
cord-256444-grw5s2pf	61	32	.	.	.
cord-256444-grw5s2pf	62	1	Inside	inside	IN
cord-256444-grw5s2pf	62	2	the	the	DT
cord-256444-grw5s2pf	62	3	envelope	envelope	NN
cord-256444-grw5s2pf	62	4	is	be	VBZ
cord-256444-grw5s2pf	62	5	a	a	DT
cord-256444-grw5s2pf	62	6	ribonucleoprotein	ribonucleoprotein	NN
cord-256444-grw5s2pf	62	7	(	(	-LRB-
cord-256444-grw5s2pf	62	8	RNP	RNP	NNP
cord-256444-grw5s2pf	62	9	)	)	-RRB-
cord-256444-grw5s2pf	62	10	core	core	NN
cord-256444-grw5s2pf	62	11	,	,	,
cord-256444-grw5s2pf	62	12	which	which	WDT
cord-256444-grw5s2pf	62	13	comprises	comprise	VBZ
cord-256444-grw5s2pf	62	14	the	the	DT
cord-256444-grw5s2pf	62	15	RNA	RNA	NNP
cord-256444-grw5s2pf	62	16	genome	genome	NN
cord-256444-grw5s2pf	62	17	and	and	CC
cord-256444-grw5s2pf	62	18	a	a	DT
cord-256444-grw5s2pf	62	19	single	single	JJ
cord-256444-grw5s2pf	62	20	species	specie	NNS
cord-256444-grw5s2pf	62	21	of	of	IN
cord-256444-grw5s2pf	62	22	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	62	23	protein	protein	NN
cord-256444-grw5s2pf	62	24	N.	N.	NNP
cord-256444-grw5s2pf	62	25	Electron	Electron	NNP
cord-256444-grw5s2pf	62	26	microscopic	microscopic	JJ
cord-256444-grw5s2pf	62	27	observation	observation	NN
cord-256444-grw5s2pf	62	28	of	of	IN
cord-256444-grw5s2pf	62	29	viral	viral	JJ
cord-256444-grw5s2pf	62	30	RNP	RNP	NNP
cord-256444-grw5s2pf	62	31	showed	show	VBD
cord-256444-grw5s2pf	62	32	a	a	DT
cord-256444-grw5s2pf	62	33	long	long	JJ
cord-256444-grw5s2pf	62	34	helix	helix	NN
cord-256444-grw5s2pf	62	35	of	of	IN
cord-256444-grw5s2pf	62	36	14	14	CD
cord-256444-grw5s2pf	62	37	to	to	TO
cord-256444-grw5s2pf	62	38	16	16	CD
cord-256444-grw5s2pf	62	39	nm	nm	NN
cord-256444-grw5s2pf	63	1	(	(	-LRB-
cord-256444-grw5s2pf	63	2	Macnaughton	Macnaughton	NNP
cord-256444-grw5s2pf	63	3	et	et	FW
cord-256444-grw5s2pf	63	4	al	al	NNP
cord-256444-grw5s2pf	63	5	.	.	.
cord-256444-grw5s2pf	64	1	,	,	,
cord-256444-grw5s2pf	64	2	1978	1978	CD
cord-256444-grw5s2pf	64	3	;	;	:
cord-256444-grw5s2pf	64	4	Sturman	Sturman	NNP
cord-256444-grw5s2pf	64	5	and	and	CC
cord-256444-grw5s2pf	64	6	Holmes	Holmes	NNP
cord-256444-grw5s2pf	64	7	,	,	,
cord-256444-grw5s2pf	64	8	1983	1983	CD
cord-256444-grw5s2pf	64	9	)	)	-RRB-
cord-256444-grw5s2pf	64	10	.	.	.
cord-256444-grw5s2pf	65	1	A	a	DT
cord-256444-grw5s2pf	65	2	very	very	RB
cord-256444-grw5s2pf	65	3	recent	recent	JJ
cord-256444-grw5s2pf	65	4	study	study	NN
cord-256444-grw5s2pf	65	5	of	of	IN
cord-256444-grw5s2pf	65	6	intact	intact	JJ
cord-256444-grw5s2pf	65	7	and	and	CC
cord-256444-grw5s2pf	65	8	detergent	detergent	NN
cord-256444-grw5s2pf	65	9	-	-	HYPH
cord-256444-grw5s2pf	65	10	treated	treat	VBN
cord-256444-grw5s2pf	65	11	TGEV	TGEV	NNP
cord-256444-grw5s2pf	65	12	virions	virion	NNS
cord-256444-grw5s2pf	65	13	(	(	-LRB-
cord-256444-grw5s2pf	65	14	Risco	Risco	NNP
cord-256444-grw5s2pf	65	15	et	et	NNP
cord-256444-grw5s2pf	65	16	al	al	NNP
cord-256444-grw5s2pf	65	17	.	.	NNP
cord-256444-grw5s2pf	65	18	,	,	,
cord-256444-grw5s2pf	65	19	1996	1996	CD
cord-256444-grw5s2pf	65	20	)	)	-RRB-
cord-256444-grw5s2pf	65	21	by	by	IN
cord-256444-grw5s2pf	65	22	negative	negative	JJ
cord-256444-grw5s2pf	65	23	-	-	HYPH
cord-256444-grw5s2pf	65	24	staining	stain	VBG
cord-256444-grw5s2pf	65	25	,	,	,
cord-256444-grw5s2pf	65	26	ultrathin	ultrathin	JJ
cord-256444-grw5s2pf	65	27	sectioning	sectioning	NN
cord-256444-grw5s2pf	65	28	,	,	,
cord-256444-grw5s2pf	65	29	freezefracture	freezefracture	NN
cord-256444-grw5s2pf	65	30	,	,	,
cord-256444-grw5s2pf	65	31	immunogold	immunogold	JJ
cord-256444-grw5s2pf	65	32	mapping	mapping	NN
cord-256444-grw5s2pf	65	33	and	and	CC
cord-256444-grw5s2pf	65	34	cryoelectron	cryoelectron	NNP
cord-256444-grw5s2pf	65	35	microscopy	microscopy	NNP
cord-256444-grw5s2pf	65	36	showed	show	VBD
cord-256444-grw5s2pf	65	37	a	a	DT
cord-256444-grw5s2pf	65	38	surprising	surprising	JJ
cord-256444-grw5s2pf	65	39	new	new	JJ
cord-256444-grw5s2pf	65	40	feature	feature	NN
cord-256444-grw5s2pf	65	41	of	of	IN
cord-256444-grw5s2pf	65	42	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	65	43	particles	particle	NNS
cord-256444-grw5s2pf	65	44	,	,	,
cord-256444-grw5s2pf	65	45	namely	namely	RB
cord-256444-grw5s2pf	65	46	,	,	,
cord-256444-grw5s2pf	65	47	a	a	DT
cord-256444-grw5s2pf	65	48	spherical	spherical	JJ
cord-256444-grw5s2pf	65	49	,	,	,
cord-256444-grw5s2pf	65	50	probably	probably	RB
cord-256444-grw5s2pf	65	51	icosahedral	icosahedral	JJ
cord-256444-grw5s2pf	65	52	,	,	,
cord-256444-grw5s2pf	65	53	core	core	NN
cord-256444-grw5s2pf	65	54	inside	inside	IN
cord-256444-grw5s2pf	65	55	the	the	DT
cord-256444-grw5s2pf	65	56	virion	virion	NN
cord-256444-grw5s2pf	65	57	(	(	-LRB-
cord-256444-grw5s2pf	65	58	Fig	Fig	NNP
cord-256444-grw5s2pf	65	59	.	.	.
cord-256444-grw5s2pf	65	60	3	3	CD
cord-256444-grw5s2pf	65	61	)	)	-RRB-
cord-256444-grw5s2pf	65	62	.	.	.
cord-256444-grw5s2pf	66	1	These	these	DT
cord-256444-grw5s2pf	66	2	internal	internal	JJ
cord-256444-grw5s2pf	66	3	cores	core	NNS
cord-256444-grw5s2pf	66	4	comprise	comprise	VBP
cord-256444-grw5s2pf	66	5	not	not	RB
cord-256444-grw5s2pf	66	6	only	only	RB
cord-256444-grw5s2pf	66	7	the	the	DT
cord-256444-grw5s2pf	66	8	N	N	NNP
cord-256444-grw5s2pf	66	9	protein	protein	NN
cord-256444-grw5s2pf	66	10	and	and	CC
cord-256444-grw5s2pf	66	11	RNA	RNA	NNP
cord-256444-grw5s2pf	66	12	but	but	CC
cord-256444-grw5s2pf	66	13	also	also	RB
cord-256444-grw5s2pf	66	14	the	the	DT
cord-256444-grw5s2pf	66	15	M	M	NNP
cord-256444-grw5s2pf	66	16	protein	protein	NN
cord-256444-grw5s2pf	66	17	,	,	.
cord-256444-grw5s2pf	67	1	M	M	NNP
cord-256444-grw5s2pf	67	2	being	be	VBG
cord-256444-grw5s2pf	67	3	the	the	DT
cord-256444-grw5s2pf	67	4	major	major	JJ
cord-256444-grw5s2pf	67	5	core	core	NN
cord-256444-grw5s2pf	67	6	shell	shell	NN
cord-256444-grw5s2pf	67	7	component	component	NN
cord-256444-grw5s2pf	67	8	.	.	.
cord-256444-grw5s2pf	68	1	Disruption	disruption	NN
cord-256444-grw5s2pf	68	2	of	of	IN
cord-256444-grw5s2pf	68	3	the	the	DT
cord-256444-grw5s2pf	68	4	cores	core	NNS
cord-256444-grw5s2pf	68	5	released	release	VBD
cord-256444-grw5s2pf	68	6	helical	helical	JJ
cord-256444-grw5s2pf	68	7	nucleocapsids	nucleocapsid	NNS
cord-256444-grw5s2pf	68	8	.	.	.
cord-256444-grw5s2pf	69	1	The	the	DT
cord-256444-grw5s2pf	69	2	presence	presence	NN
cord-256444-grw5s2pf	69	3	of	of	IN
cord-256444-grw5s2pf	69	4	an	an	DT
cord-256444-grw5s2pf	69	5	icosahedral	icosahedral	JJ
cord-256444-grw5s2pf	69	6	core	core	NN
cord-256444-grw5s2pf	69	7	in	in	IN
cord-256444-grw5s2pf	69	8	the	the	DT
cord-256444-grw5s2pf	69	9	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	69	10	virion	virion	NN
cord-256444-grw5s2pf	69	11	had	have	VBD
cord-256444-grw5s2pf	69	12	heretofore	heretofore	RB
cord-256444-grw5s2pf	69	13	been	be	VBN
cord-256444-grw5s2pf	69	14	unsuspected	unsuspected	JJ
cord-256444-grw5s2pf	69	15	.	.	.
cord-256444-grw5s2pf	70	1	This	this	DT
cord-256444-grw5s2pf	70	2	core	core	NN
cord-256444-grw5s2pf	70	3	structure	structure	NN
cord-256444-grw5s2pf	70	4	was	be	VBD
cord-256444-grw5s2pf	70	5	also	also	RB
cord-256444-grw5s2pf	70	6	detected	detect	VBN
cord-256444-grw5s2pf	70	7	with	with	IN
cord-256444-grw5s2pf	70	8	MHV	MHV	NNP
cord-256444-grw5s2pf	70	9	virion	virion	NN
cord-256444-grw5s2pf	70	10	(	(	-LRB-
cord-256444-grw5s2pf	70	11	Risco	Risco	NNP
cord-256444-grw5s2pf	70	12	et	et	NNP
cord-256444-grw5s2pf	70	13	al	al	NNP
cord-256444-grw5s2pf	70	14	.	.	NNP
cord-256444-grw5s2pf	70	15	,	,	,
cord-256444-grw5s2pf	70	16	1996	1996	CD
cord-256444-grw5s2pf	70	17	)	)	-RRB-
cord-256444-grw5s2pf	70	18	.	.	.
cord-256444-grw5s2pf	71	1	This	this	DT
cord-256444-grw5s2pf	71	2	surprising	surprising	JJ
cord-256444-grw5s2pf	71	3	new	new	JJ
cord-256444-grw5s2pf	71	4	finding	finding	NN
cord-256444-grw5s2pf	71	5	gives	give	VBZ
cord-256444-grw5s2pf	71	6	us	-PRON-	PRP
cord-256444-grw5s2pf	71	7	cause	cause	NN
cord-256444-grw5s2pf	71	8	to	to	TO
cord-256444-grw5s2pf	71	9	reconsider	reconsider	VB
cord-256444-grw5s2pf	71	10	our	-PRON-	PRP$
cord-256444-grw5s2pf	71	11	view	view	NN
cord-256444-grw5s2pf	71	12	of	of	IN
cord-256444-grw5s2pf	71	13	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	71	14	architecture	architecture	NN
cord-256444-grw5s2pf	71	15	.	.	.
cord-256444-grw5s2pf	72	1	Thus	thus	RB
cord-256444-grw5s2pf	72	2	,	,	,
cord-256444-grw5s2pf	72	3	the	the	DT
cord-256444-grw5s2pf	72	4	precise	precise	JJ
cord-256444-grw5s2pf	72	5	structure	structure	NN
cord-256444-grw5s2pf	72	6	of	of	IN
cord-256444-grw5s2pf	72	7	the	the	DT
cord-256444-grw5s2pf	72	8	core	core	NN
cord-256444-grw5s2pf	72	9	and	and	CC
cord-256444-grw5s2pf	72	10	RNP	RNP	NNP
cord-256444-grw5s2pf	72	11	inside	inside	IN
cord-256444-grw5s2pf	72	12	the	the	DT
cord-256444-grw5s2pf	72	13	virion	virion	NN
cord-256444-grw5s2pf	72	14	is	be	VBZ
cord-256444-grw5s2pf	72	15	not	not	RB
cord-256444-grw5s2pf	72	16	certain	certain	JJ
cord-256444-grw5s2pf	72	17	.	.	.
cord-256444-grw5s2pf	73	1	Toroviruses	toroviruse	NNS
cord-256444-grw5s2pf	73	2	and	and	CC
cord-256444-grw5s2pf	73	3	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	73	4	have	have	VBP
cord-256444-grw5s2pf	73	5	a	a	DT
cord-256444-grw5s2pf	73	6	similar	similar	JJ
cord-256444-grw5s2pf	73	7	morphology	morphology	NN
cord-256444-grw5s2pf	73	8	and	and	CC
cord-256444-grw5s2pf	73	9	virion	virion	NN
cord-256444-grw5s2pf	73	10	composition	composition	NN
cord-256444-grw5s2pf	73	11	(	(	-LRB-
cord-256444-grw5s2pf	73	12	Fig	Fig	NNP
cord-256444-grw5s2pf	73	13	.	.	NNP
cord-256444-grw5s2pf	73	14	1	1	CD
cord-256444-grw5s2pf	73	15	,	,	,
cord-256444-grw5s2pf	73	16	Table	table	NN
cord-256444-grw5s2pf	73	17	11	11	CD
cord-256444-grw5s2pf	73	18	)	)	-RRB-
cord-256444-grw5s2pf	73	19	but	but	CC
cord-256444-grw5s2pf	73	20	are	be	VBP
cord-256444-grw5s2pf	73	21	distinguishable	distinguishable	JJ
cord-256444-grw5s2pf	73	22	in	in	IN
cord-256444-grw5s2pf	73	23	a	a	DT
cord-256444-grw5s2pf	73	24	number	number	NN
cord-256444-grw5s2pf	73	25	of	of	IN
cord-256444-grw5s2pf	73	26	ways	way	NNS
cord-256444-grw5s2pf	73	27	(	(	-LRB-
cord-256444-grw5s2pf	73	28	Table	table	NN
cord-256444-grw5s2pf	73	29	11	11	CD
cord-256444-grw5s2pf	73	30	)	)	-RRB-
cord-256444-grw5s2pf	74	1	(	(	-LRB-
cord-256444-grw5s2pf	74	2	Weiss	Weiss	NNP
cord-256444-grw5s2pf	74	3	and	and	CC
cord-256444-grw5s2pf	74	4	Horzinek	Horzinek	NNP
cord-256444-grw5s2pf	74	5	,	,	,
cord-256444-grw5s2pf	74	6	1987	1987	CD
cord-256444-grw5s2pf	74	7	;	;	:
cord-256444-grw5s2pf	74	8	Horzinek	Horzinek	NNP
cord-256444-grw5s2pf	74	9	,	,	,
cord-256444-grw5s2pf	74	10	1993	1993	CD
cord-256444-grw5s2pf	74	11	,	,	,
cord-256444-grw5s2pf	74	12	1995	1995	CD
cord-256444-grw5s2pf	74	13	;	;	:
cord-256444-grw5s2pf	74	14	Koopmans	Koopmans	NNPS
cord-256444-grw5s2pf	74	15	and	and	CC
cord-256444-grw5s2pf	74	16	Horzinek	Horzinek	NNP
cord-256444-grw5s2pf	74	17	,	,	,
cord-256444-grw5s2pf	74	18	1994	1994	CD
cord-256444-grw5s2pf	74	19	)	)	-RRB-
cord-256444-grw5s2pf	74	20	,	,	,
cord-256444-grw5s2pf	74	21	necessitating	necessitate	VBG
cord-256444-grw5s2pf	74	22	their	-PRON-	PRP$
cord-256444-grw5s2pf	74	23	inclusion	inclusion	NN
cord-256444-grw5s2pf	74	24	in	in	IN
cord-256444-grw5s2pf	74	25	separate	separate	JJ
cord-256444-grw5s2pf	74	26	genera	genus	NNS
cord-256444-grw5s2pf	74	27	.	.	.
cord-256444-grw5s2pf	75	1	The	the	DT
cord-256444-grw5s2pf	75	2	morphology	morphology	NN
cord-256444-grw5s2pf	75	3	of	of	IN
cord-256444-grw5s2pf	75	4	the	the	DT
cord-256444-grw5s2pf	75	5	arteriviruses	arteriviruse	NNS
cord-256444-grw5s2pf	75	6	is	be	VBZ
cord-256444-grw5s2pf	75	7	substantially	substantially	RB
cord-256444-grw5s2pf	75	8	different	different	JJ
cord-256444-grw5s2pf	75	9	from	from	IN
cord-256444-grw5s2pf	75	10	that	that	DT
cord-256444-grw5s2pf	75	11	of	of	IN
cord-256444-grw5s2pf	75	12	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	75	13	and	and	CC
cord-256444-grw5s2pf	75	14	toroviruses	toroviruse	NNS
cord-256444-grw5s2pf	75	15	,	,	,
cord-256444-grw5s2pf	75	16	particularly	particularly	RB
cord-256444-grw5s2pf	75	17	in	in	IN
cord-256444-grw5s2pf	75	18	having	have	VBG
cord-256444-grw5s2pf	75	19	an	an	DT
cord-256444-grw5s2pf	75	20	icosahedral	icosahedral	JJ
cord-256444-grw5s2pf	75	21	RNP	RNP	NNP
cord-256444-grw5s2pf	75	22	core	core	NN
cord-256444-grw5s2pf	75	23	(	(	-LRB-
cord-256444-grw5s2pf	75	24	Fig	Fig	NNP
cord-256444-grw5s2pf	75	25	.	.	.
cord-256444-grw5s2pf	75	26	1	1	CD
cord-256444-grw5s2pf	75	27	)	)	-RRB-
cord-256444-grw5s2pf	75	28	;	;	:
cord-256444-grw5s2pf	75	29	hence	hence	RB
cord-256444-grw5s2pf	75	30	,	,	,
cord-256444-grw5s2pf	75	31	a	a	DT
cord-256444-grw5s2pf	75	32	separate	separate	JJ
cord-256444-grw5s2pf	75	33	family	family	NN
cord-256444-grw5s2pf	75	34	is	be	VBZ
cord-256444-grw5s2pf	75	35	maintained	maintain	VBN
cord-256444-grw5s2pf	75	36	for	for	IN
cord-256444-grw5s2pf	75	37	arteriviruses	arteriviruse	NNS
cord-256444-grw5s2pf	75	38	.	.	.
cord-256444-grw5s2pf	76	1	However	however	RB
cord-256444-grw5s2pf	76	2	,	,	,
cord-256444-grw5s2pf	76	3	the	the	DT
cord-256444-grw5s2pf	76	4	recent	recent	JJ
cord-256444-grw5s2pf	76	5	discovery	discovery	NN
cord-256444-grw5s2pf	76	6	of	of	IN
cord-256444-grw5s2pf	76	7	the	the	DT
cord-256444-grw5s2pf	76	8	icosahedral	icosahedral	JJ
cord-256444-grw5s2pf	76	9	core	core	NN
cord-256444-grw5s2pf	76	10	for	for	IN
cord-256444-grw5s2pf	76	11	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	77	1	(	(	-LRB-
cord-256444-grw5s2pf	77	2	Risco	Risco	NNP
cord-256444-grw5s2pf	77	3	et	et	NNP
cord-256444-grw5s2pf	77	4	al	al	NNP
cord-256444-grw5s2pf	77	5	.	.	NNP
cord-256444-grw5s2pf	77	6	,	,	,
cord-256444-grw5s2pf	77	7	1996	1996	CD
cord-256444-grw5s2pf	77	8	)	)	-RRB-
cord-256444-grw5s2pf	77	9	may	may	MD
cord-256444-grw5s2pf	77	10	have	have	VB
cord-256444-grw5s2pf	77	11	blurred	blur	VBN
cord-256444-grw5s2pf	77	12	this	this	DT
cord-256444-grw5s2pf	77	13	distinction	distinction	NN
cord-256444-grw5s2pf	77	14	.	.	.
cord-256444-grw5s2pf	78	1	The	the	DT
cord-256444-grw5s2pf	78	2	S	S	NNP
cord-256444-grw5s2pf	78	3	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	78	4	is	be	VBZ
cord-256444-grw5s2pf	78	5	the	the	DT
cord-256444-grw5s2pf	78	6	outermost	outermost	JJS
cord-256444-grw5s2pf	78	7	component	component	NN
cord-256444-grw5s2pf	78	8	of	of	IN
cord-256444-grw5s2pf	78	9	the	the	DT
cord-256444-grw5s2pf	78	10	virion	virion	NN
cord-256444-grw5s2pf	78	11	,	,	,
cord-256444-grw5s2pf	78	12	and	and	CC
cord-256444-grw5s2pf	78	13	is	be	VBZ
cord-256444-grw5s2pf	78	14	responsible	responsible	JJ
cord-256444-grw5s2pf	78	15	for	for	IN
cord-256444-grw5s2pf	78	16	the	the	DT
cord-256444-grw5s2pf	78	17	attachment	attachment	NN
cord-256444-grw5s2pf	78	18	of	of	IN
cord-256444-grw5s2pf	78	19	the	the	DT
cord-256444-grw5s2pf	78	20	virus	virus	NN
cord-256444-grw5s2pf	78	21	to	to	IN
cord-256444-grw5s2pf	78	22	cells	cell	NNS
cord-256444-grw5s2pf	78	23	(	(	-LRB-
cord-256444-grw5s2pf	78	24	Collins	Collins	NNP
cord-256444-grw5s2pf	78	25	et	et	NNP
cord-256444-grw5s2pf	78	26	al	al	NNP
cord-256444-grw5s2pf	78	27	.	.	NNP
cord-256444-grw5s2pf	78	28	,	,	,
cord-256444-grw5s2pf	78	29	1982	1982	CD
cord-256444-grw5s2pf	78	30	;	;	:
cord-256444-grw5s2pf	78	31	Godet	Godet	NNP
cord-256444-grw5s2pf	78	32	et	et	NNP
cord-256444-grw5s2pf	78	33	al	al	NNP
cord-256444-grw5s2pf	78	34	.	.	NNP
cord-256444-grw5s2pf	78	35	,	,	,
cord-256444-grw5s2pf	78	36	1994	1994	CD
cord-256444-grw5s2pf	78	37	;	;	:
cord-256444-grw5s2pf	78	38	Kubo	Kubo	NNP
cord-256444-grw5s2pf	78	39	et	et	NNP
cord-256444-grw5s2pf	78	40	al	al	NNP
cord-256444-grw5s2pf	78	41	.	.	NNP
cord-256444-grw5s2pf	78	42	,	,	,
cord-256444-grw5s2pf	78	43	1994	1994	CD
cord-256444-grw5s2pf	78	44	)	)	-RRB-
cord-256444-grw5s2pf	78	45	and	and	CC
cord-256444-grw5s2pf	78	46	for	for	IN
cord-256444-grw5s2pf	78	47	instigating	instigate	VBG
cord-256444-grw5s2pf	78	48	the	the	DT
cord-256444-grw5s2pf	78	49	fusion	fusion	NN
cord-256444-grw5s2pf	78	50	of	of	IN
cord-256444-grw5s2pf	78	51	the	the	DT
cord-256444-grw5s2pf	78	52	virus	virus	NN
cord-256444-grw5s2pf	78	53	envelope	envelope	NN
cord-256444-grw5s2pf	78	54	with	with	IN
cord-256444-grw5s2pf	78	55	cell	cell	NN
cord-256444-grw5s2pf	78	56	membranes	membrane	NNS
cord-256444-grw5s2pf	78	57	.	.	.
cord-256444-grw5s2pf	79	1	It	-PRON-	PRP
cord-256444-grw5s2pf	79	2	is	be	VBZ
cord-256444-grw5s2pf	79	3	the	the	DT
cord-256444-grw5s2pf	79	4	primary	primary	JJ
cord-256444-grw5s2pf	79	5	target	target	NN
cord-256444-grw5s2pf	79	6	for	for	IN
cord-256444-grw5s2pf	79	7	the	the	DT
cord-256444-grw5s2pf	79	8	host	host	NN
cord-256444-grw5s2pf	79	9	's	's	POS
cord-256444-grw5s2pf	79	10	immune	immune	JJ
cord-256444-grw5s2pf	79	11	responses	response	NNS
cord-256444-grw5s2pf	79	12	;	;	,
cord-256444-grw5s2pf	79	13	neutralizing	neutralize	VBG
cord-256444-grw5s2pf	79	14	antibodies	antibody	NNS
cord-256444-grw5s2pf	79	15	are	be	VBP
cord-256444-grw5s2pf	79	16	induced	induce	VBN
cord-256444-grw5s2pf	79	17	mainly	mainly	RB
cord-256444-grw5s2pf	79	18	by	by	IN
cord-256444-grw5s2pf	79	19	S	S	NNP
cord-256444-grw5s2pf	79	20	(	(	-LRB-
cord-256444-grw5s2pf	79	21	Collins	Collins	NNP
cord-256444-grw5s2pf	79	22	et	et	NNP
cord-256444-grw5s2pf	79	23	al	al	NNP
cord-256444-grw5s2pf	79	24	.	.	NNP
cord-256444-grw5s2pf	79	25	,	,	,
cord-256444-grw5s2pf	79	26	19821	19821	CD
cord-256444-grw5s2pf	79	27	,	,	,
cord-256444-grw5s2pf	79	28	and	and	CC
cord-256444-grw5s2pf	79	29	immunization	immunization	NN
cord-256444-grw5s2pf	79	30	in	in	IN
cord-256444-grw5s2pf	79	31	animals	animal	NNS
cord-256444-grw5s2pf	79	32	with	with	IN
cord-256444-grw5s2pf	79	33	S	s	NN
cord-256444-grw5s2pf	79	34	alone	alone	RB
cord-256444-grw5s2pf	79	35	can	can	MD
cord-256444-grw5s2pf	79	36	induce	induce	VB
cord-256444-grw5s2pf	79	37	protection	protection	NN
cord-256444-grw5s2pf	79	38	from	from	IN
cord-256444-grw5s2pf	79	39	some	some	DT
cord-256444-grw5s2pf	79	40	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	79	41	(	(	-LRB-
cord-256444-grw5s2pf	79	42	Ignjatovic	Ignjatovic	NNP
cord-256444-grw5s2pf	79	43	and	and	CC
cord-256444-grw5s2pf	79	44	Galli	Galli	NNP
cord-256444-grw5s2pf	79	45	,	,	,
cord-256444-grw5s2pf	79	46	1994	1994	CD
cord-256444-grw5s2pf	79	47	;	;	:
cord-256444-grw5s2pf	79	48	Torres	Torres	NNP
cord-256444-grw5s2pf	79	49	et	et	NNP
cord-256444-grw5s2pf	79	50	al	al	NNP
cord-256444-grw5s2pf	79	51	.	.	NNP
cord-256444-grw5s2pf	79	52	,	,	,
cord-256444-grw5s2pf	79	53	1995	1995	CD
cord-256444-grw5s2pf	79	54	)	)	-RRB-
cord-256444-grw5s2pf	79	55	.	.	.
cord-256444-grw5s2pf	80	1	Within	within	IN
cord-256444-grw5s2pf	80	2	a	a	DT
cord-256444-grw5s2pf	80	3	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	80	4	species	species	NN
cord-256444-grw5s2pf	80	5	,	,	,
cord-256444-grw5s2pf	80	6	sequence	sequence	NN
cord-256444-grw5s2pf	80	7	variation	variation	NN
cord-256444-grw5s2pf	80	8	is	be	VBZ
cord-256444-grw5s2pf	80	9	usually	usually	RB
cord-256444-grw5s2pf	80	10	exhibited	exhibit	VBN
cord-256444-grw5s2pf	80	11	more	more	JJR
cord-256444-grw5s2pf	80	12	by	by	IN
cord-256444-grw5s2pf	80	13	S	S	NNP
cord-256444-grw5s2pf	80	14	than	than	IN
cord-256444-grw5s2pf	80	15	by	by	IN
cord-256444-grw5s2pf	80	16	any	any	DT
cord-256444-grw5s2pf	80	17	other	other	JJ
cord-256444-grw5s2pf	80	18	structural	structural	JJ
cord-256444-grw5s2pf	80	19	proteins	protein	NNS
cord-256444-grw5s2pf	80	20	;	;	:
cord-256444-grw5s2pf	80	21	the	the	DT
cord-256444-grw5s2pf	80	22	variation	variation	NN
cord-256444-grw5s2pf	80	23	of	of	IN
cord-256444-grw5s2pf	80	24	the	the	DT
cord-256444-grw5s2pf	80	25	S	S	NNP
cord-256444-grw5s2pf	80	26	protein	protein	NN
cord-256444-grw5s2pf	80	27	sequence	sequence	NN
cord-256444-grw5s2pf	80	28	probably	probably	RB
cord-256444-grw5s2pf	80	29	confers	confer	VBZ
cord-256444-grw5s2pf	80	30	a	a	DT
cord-256444-grw5s2pf	80	31	selective	selective	JJ
cord-256444-grw5s2pf	80	32	advantage	advantage	NN
cord-256444-grw5s2pf	80	33	in	in	IN
cord-256444-grw5s2pf	80	34	immune	immune	JJ
cord-256444-grw5s2pf	80	35	animals	animal	NNS
cord-256444-grw5s2pf	80	36	.	.	.
cord-256444-grw5s2pf	81	1	These	these	DT
cord-256444-grw5s2pf	81	2	and	and	CC
cord-256444-grw5s2pf	81	3	other	other	JJ
cord-256444-grw5s2pf	81	4	aspects	aspect	NNS
cord-256444-grw5s2pf	81	5	have	have	VBP
cord-256444-grw5s2pf	81	6	recently	recently	RB
cord-256444-grw5s2pf	81	7	been	be	VBN
cord-256444-grw5s2pf	81	8	reviewed	review	VBN
cord-256444-grw5s2pf	81	9	in	in	IN
cord-256444-grw5s2pf	81	10	detail	detail	NN
cord-256444-grw5s2pf	81	11	.	.	.
cord-256444-grw5s2pf	82	1	The	the	DT
cord-256444-grw5s2pf	82	2	S	S	NNP
cord-256444-grw5s2pf	82	3	protein	protein	NN
cord-256444-grw5s2pf	82	4	is	be	VBZ
cord-256444-grw5s2pf	82	5	large	large	JJ
cord-256444-grw5s2pf	82	6	,	,	,
cord-256444-grw5s2pf	82	7	ranging	range	VBG
cord-256444-grw5s2pf	82	8	from	from	IN
cord-256444-grw5s2pf	82	9	some	some	DT
cord-256444-grw5s2pf	82	10	1160	1160	CD
cord-256444-grw5s2pf	82	11	(	(	-LRB-
cord-256444-grw5s2pf	82	12	IBV	IBV	NNP
cord-256444-grw5s2pf	82	13	)	)	-RRB-
cord-256444-grw5s2pf	82	14	to	to	IN
cord-256444-grw5s2pf	82	15	1452	1452	CD
cord-256444-grw5s2pf	82	16	amino	amino	NN
cord-256444-grw5s2pf	82	17	acids	acid	NNS
cord-256444-grw5s2pf	82	18	(	(	-LRB-
cord-256444-grw5s2pf	82	19	FCV	FCV	NNP
cord-256444-grw5s2pf	82	20	)	)	-RRB-
cord-256444-grw5s2pf	82	21	.	.	.
cord-256444-grw5s2pf	83	1	There	there	EX
cord-256444-grw5s2pf	83	2	are	be	VBP
cord-256444-grw5s2pf	83	3	many	many	JJ
cord-256444-grw5s2pf	83	4	potential	potential	JJ
cord-256444-grw5s2pf	83	5	N	n	CD
cord-256444-grw5s2pf	83	6	-	-	HYPH
cord-256444-grw5s2pf	83	7	linked	link	VBN
cord-256444-grw5s2pf	83	8	glycosylation	glycosylation	NN
cord-256444-grw5s2pf	83	9	sites	site	NNS
cord-256444-grw5s2pf	83	10	(	(	-LRB-
cord-256444-grw5s2pf	83	11	21	21	CD
cord-256444-grw5s2pf	83	12	to	to	IN
cord-256444-grw5s2pf	83	13	351	351	CD
cord-256444-grw5s2pf	83	14	,	,	,
cord-256444-grw5s2pf	83	15	most	most	JJS
cord-256444-grw5s2pf	83	16	of	of	IN
cord-256444-grw5s2pf	83	17	which	which	WDT
cord-256444-grw5s2pf	83	18	have	have	VBP
cord-256444-grw5s2pf	83	19	glycans	glycan	NNS
cord-256444-grw5s2pf	83	20	attached	attach	VBN
cord-256444-grw5s2pf	83	21	.	.	.
cord-256444-grw5s2pf	84	1	The	the	DT
cord-256444-grw5s2pf	84	2	S	S	NNP
cord-256444-grw5s2pf	84	3	preproprotein	preproprotein	NN
cord-256444-grw5s2pf	84	4	has	have	VBZ
cord-256444-grw5s2pf	84	5	a	a	DT
cord-256444-grw5s2pf	84	6	N	n	CD
cord-256444-grw5s2pf	84	7	-	-	HYPH
cord-256444-grw5s2pf	84	8	terminal	terminal	JJ
cord-256444-grw5s2pf	84	9	signal	signal	NN
cord-256444-grw5s2pf	84	10	sequence	sequence	NN
cord-256444-grw5s2pf	84	11	and	and	CC
cord-256444-grw5s2pf	84	12	a	a	DT
cord-256444-grw5s2pf	84	13	membrane	membrane	NN
cord-256444-grw5s2pf	84	14	-	-	HYPH
cord-256444-grw5s2pf	84	15	anchoring	anchor	VBG
cord-256444-grw5s2pf	84	16	sequence	sequence	NN
cord-256444-grw5s2pf	84	17	near	near	IN
cord-256444-grw5s2pf	84	18	the	the	DT
cord-256444-grw5s2pf	84	19	C	C	NNP
cord-256444-grw5s2pf	84	20	terminus	terminus	NN
cord-256444-grw5s2pf	84	21	(	(	-LRB-
cord-256444-grw5s2pf	84	22	Fig	Fig	NNP
cord-256444-grw5s2pf	84	23	.	.	.
cord-256444-grw5s2pf	84	24	4	4	CD
cord-256444-grw5s2pf	84	25	)	)	-RRB-
cord-256444-grw5s2pf	84	26	.	.	.
cord-256444-grw5s2pf	85	1	The	the	DT
cord-256444-grw5s2pf	85	2	S	S	NNP
cord-256444-grw5s2pf	85	3	protein	protein	NN
cord-256444-grw5s2pf	85	4	may	may	MD
cord-256444-grw5s2pf	85	5	be	be	VB
cord-256444-grw5s2pf	85	6	cleaved	cleave	VBN
cord-256444-grw5s2pf	85	7	into	into	IN
cord-256444-grw5s2pf	85	8	S1	S1	NNP
cord-256444-grw5s2pf	85	9	and	and	CC
cord-256444-grw5s2pf	85	10	S2	S2	NNP
cord-256444-grw5s2pf	85	11	subunits	subunit	NNS
cord-256444-grw5s2pf	85	12	;	;	:
cord-256444-grw5s2pf	85	13	the	the	DT
cord-256444-grw5s2pf	85	14	extent	extent	NN
cord-256444-grw5s2pf	85	15	of	of	IN
cord-256444-grw5s2pf	85	16	its	-PRON-	PRP$
cord-256444-grw5s2pf	85	17	cleavage	cleavage	NN
cord-256444-grw5s2pf	85	18	varies	vary	VBZ
cord-256444-grw5s2pf	85	19	greatly	greatly	RB
cord-256444-grw5s2pf	85	20	among	among	IN
cord-256444-grw5s2pf	85	21	the	the	DT
cord-256444-grw5s2pf	85	22	species	specie	NNS
cord-256444-grw5s2pf	85	23	(	(	-LRB-
cord-256444-grw5s2pf	85	24	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	85	25	,	,	,
cord-256444-grw5s2pf	85	26	1995	1995	CD
cord-256444-grw5s2pf	85	27	)	)	-RRB-
cord-256444-grw5s2pf	85	28	.	.	.
cord-256444-grw5s2pf	86	1	A	a	DT
cord-256444-grw5s2pf	86	2	high	high	JJ
cord-256444-grw5s2pf	86	3	proportion	proportion	NN
cord-256444-grw5s2pf	86	4	,	,	,
cord-256444-grw5s2pf	86	5	up	up	IN
cord-256444-grw5s2pf	86	6	to	to	IN
cord-256444-grw5s2pf	86	7	loo%	loo%	NNP
cord-256444-grw5s2pf	86	8	,	,	,
cord-256444-grw5s2pf	86	9	of	of	IN
cord-256444-grw5s2pf	86	10	the	the	DT
cord-256444-grw5s2pf	86	11	S	S	NNP
cord-256444-grw5s2pf	86	12	protein	protein	NN
cord-256444-grw5s2pf	86	13	is	be	VBZ
cord-256444-grw5s2pf	86	14	cleaved	cleave	VBN
cord-256444-grw5s2pf	86	15	in	in	IN
cord-256444-grw5s2pf	86	16	some	some	DT
cord-256444-grw5s2pf	86	17	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	86	18	(	(	-LRB-
cord-256444-grw5s2pf	86	19	IBV	IBV	NNP
cord-256444-grw5s2pf	86	20	,	,	,
cord-256444-grw5s2pf	86	21	MHV	MHV	NNP
cord-256444-grw5s2pf	86	22	,	,	,
cord-256444-grw5s2pf	86	23	BCV	BCV	NNP
cord-256444-grw5s2pf	86	24	,	,	,
cord-256444-grw5s2pf	86	25	TCV	TCV	NNP
cord-256444-grw5s2pf	86	26	,	,	,
cord-256444-grw5s2pf	86	27	PEDV	PEDV	NNP
cord-256444-grw5s2pf	86	28	)	)	-RRB-
cord-256444-grw5s2pf	86	29	(	(	-LRB-
cord-256444-grw5s2pf	86	30	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	86	31	,	,	,
cord-256444-grw5s2pf	86	32	1983a	1983a	CD
cord-256444-grw5s2pf	86	33	)	)	-RRB-
cord-256444-grw5s2pf	86	34	;	;	:
cord-256444-grw5s2pf	86	35	none	none	NN
cord-256444-grw5s2pf	86	36	is	be	VBZ
cord-256444-grw5s2pf	86	37	cleaved	cleave	VBN
cord-256444-grw5s2pf	86	38	in	in	IN
cord-256444-grw5s2pf	86	39	others	other	NNS
cord-256444-grw5s2pf	86	40	(	(	-LRB-
cord-256444-grw5s2pf	86	41	TGEV	TGEV	NNP
cord-256444-grw5s2pf	86	42	,	,	,
cord-256444-grw5s2pf	86	43	FCV	FCV	NNP
cord-256444-grw5s2pf	86	44	,	,	,
cord-256444-grw5s2pf	86	45	CCV	CCV	NNP
cord-256444-grw5s2pf	86	46	)	)	-RRB-
cord-256444-grw5s2pf	86	47	(	(	-LRB-
cord-256444-grw5s2pf	86	48	Garwes	Garwes	NNP
cord-256444-grw5s2pf	86	49	and	and	CC
cord-256444-grw5s2pf	86	50	Pocock	Pocock	NNP
cord-256444-grw5s2pf	86	51	,	,	,
cord-256444-grw5s2pf	86	52	1975	1975	CD
cord-256444-grw5s2pf	86	53	)	)	-RRB-
cord-256444-grw5s2pf	86	54	;	;	:
cord-256444-grw5s2pf	86	55	and	and	CC
cord-256444-grw5s2pf	86	56	very	very	RB
cord-256444-grw5s2pf	86	57	little	little	JJ
cord-256444-grw5s2pf	86	58	of	of	IN
cord-256444-grw5s2pf	86	59	the	the	DT
cord-256444-grw5s2pf	86	60	S	S	NNP
cord-256444-grw5s2pf	86	61	protein	protein	NN
cord-256444-grw5s2pf	86	62	of	of	IN
cord-256444-grw5s2pf	86	63	HCV-2293	HCV-2293	NNP
cord-256444-grw5s2pf	86	64	and	and	CC
cord-256444-grw5s2pf	86	65	HCV	HCV	NNP
cord-256444-grw5s2pf	86	66	-	-	HYPH
cord-256444-grw5s2pf	86	67	OC43	OC43	NNP
cord-256444-grw5s2pf	86	68	is	be	VBZ
cord-256444-grw5s2pf	86	69	cleaved	cleave	VBN
cord-256444-grw5s2pf	86	70	,	,	,
cord-256444-grw5s2pf	86	71	although	although	IN
cord-256444-grw5s2pf	86	72	the	the	DT
cord-256444-grw5s2pf	86	73	S	S	NNP
cord-256444-grw5s2pf	86	74	of	of	IN
cord-256444-grw5s2pf	86	75	OC43	OC43	NNP
cord-256444-grw5s2pf	86	76	is	be	VBZ
cord-256444-grw5s2pf	86	77	completely	completely	RB
cord-256444-grw5s2pf	86	78	FIG	FIG	NNP
cord-256444-grw5s2pf	86	79	1	1	CD
cord-256444-grw5s2pf	86	80	.	.	.
cord-256444-grw5s2pf	87	1	Models	model	NNS
cord-256444-grw5s2pf	87	2	of	of	IN
cord-256444-grw5s2pf	87	3	the	the	DT
cord-256444-grw5s2pf	87	4	virions	virion	NNS
cord-256444-grw5s2pf	87	5	of	of	IN
cord-256444-grw5s2pf	87	6	a	a	DT
cord-256444-grw5s2pf	87	7	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	87	8	,	,	,
cord-256444-grw5s2pf	87	9	a	a	DT
cord-256444-grw5s2pf	87	10	torovirus	torovirus	NN
cord-256444-grw5s2pf	87	11	,	,	,
cord-256444-grw5s2pf	87	12	and	and	CC
cord-256444-grw5s2pf	87	13	an	an	DT
cord-256444-grw5s2pf	87	14	arterivirus	arterivirus	NN
cord-256444-grw5s2pf	87	15	.	.	.
cord-256444-grw5s2pf	88	1	The	the	DT
cord-256444-grw5s2pf	88	2	HE	HE	NNP
cord-256444-grw5s2pf	88	3	protein	protein	NN
cord-256444-grw5s2pf	88	4	is	be	VBZ
cord-256444-grw5s2pf	88	5	present	present	JJ
cord-256444-grw5s2pf	88	6	only	only	RB
cord-256444-grw5s2pf	88	7	in	in	IN
cord-256444-grw5s2pf	88	8	antigenic	antigenic	JJ
cord-256444-grw5s2pf	88	9	group	group	NN
cord-256444-grw5s2pf	88	10	2	2	CD
cord-256444-grw5s2pf	88	11	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	88	12	(	(	-LRB-
cord-256444-grw5s2pf	88	13	see	see	VB
cord-256444-grw5s2pf	88	14	Table	table	NN
cord-256444-grw5s2pf	88	15	I	-PRON-	PRP
cord-256444-grw5s2pf	88	16	)	)	-RRB-
cord-256444-grw5s2pf	88	17	.	.	.
cord-256444-grw5s2pf	89	1	Reproduced	reproduce	VBN
cord-256444-grw5s2pf	89	2	with	with	IN
cord-256444-grw5s2pf	89	3	permission	permission	NN
cord-256444-grw5s2pf	89	4	from	from	IN
cord-256444-grw5s2pf	89	5	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	89	6	et	et	NNP
cord-256444-grw5s2pf	89	7	al	al	NNP
cord-256444-grw5s2pf	89	8	.	.	.
cord-256444-grw5s2pf	90	1	(	(	-LRB-
cord-256444-grw5s2pf	90	2	1994	1994	CD
cord-256444-grw5s2pf	90	3	)	)	-RRB-
cord-256444-grw5s2pf	90	4	.	.	.
cord-256444-grw5s2pf	91	1	Present	present	JJ
cord-256444-grw5s2pf	91	2	in	in	IN
cord-256444-grw5s2pf	91	3	only	only	RB
cord-256444-grw5s2pf	91	4	a	a	DT
cord-256444-grw5s2pf	91	5	subset	subset	NN
cord-256444-grw5s2pf	91	6	of	of	IN
cord-256444-grw5s2pf	91	7	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	91	8	(	(	-LRB-
cord-256444-grw5s2pf	91	9	Table	table	NN
cord-256444-grw5s2pf	91	10	I	i	CD
cord-256444-grw5s2pf	91	11	)	)	-RRB-
cord-256444-grw5s2pf	91	12	.	.	.
cord-256444-grw5s2pf	92	1	May	May	MD
cord-256444-grw5s2pf	92	2	have	have	VB
cord-256444-grw5s2pf	92	3	an	an	DT
cord-256444-grw5s2pf	92	4	isometric	isometric	JJ
cord-256444-grw5s2pf	92	5	core	core	NN
cord-256444-grw5s2pf	92	6	in	in	IN
cord-256444-grw5s2pf	92	7	addition	addition	NN
cord-256444-grw5s2pf	93	1	(	(	-LRB-
cord-256444-grw5s2pf	93	2	Risco	Risco	NNP
cord-256444-grw5s2pf	93	3	et	et	NNP
cord-256444-grw5s2pf	93	4	al	al	NNP
cord-256444-grw5s2pf	93	5	.	.	NNP
cord-256444-grw5s2pf	93	6	,	,	,
cord-256444-grw5s2pf	93	7	1996	1996	CD
cord-256444-grw5s2pf	93	8	)	)	-RRB-
cord-256444-grw5s2pf	93	9	.	.	.
cord-256444-grw5s2pf	94	1	No	no	DT
cord-256444-grw5s2pf	94	2	such	such	JJ
cord-256444-grw5s2pf	94	3	protein	protein	NN
cord-256444-grw5s2pf	94	4	described	describe	VBN
cord-256444-grw5s2pf	94	5	.	.	.
cord-256444-grw5s2pf	95	1	Table	table	NN
cord-256444-grw5s2pf	95	2	I	i	CD
cord-256444-grw5s2pf	95	3	)	)	-RRB-
cord-256444-grw5s2pf	95	4	and	and	CC
cord-256444-grw5s2pf	95	5	with	with	IN
cord-256444-grw5s2pf	95	6	respect	respect	NN
cord-256444-grw5s2pf	95	7	to	to	IN
cord-256444-grw5s2pf	95	8	the	the	DT
cord-256444-grw5s2pf	95	9	number	number	NN
cord-256444-grw5s2pf	95	10	and	and	CC
cord-256444-grw5s2pf	95	11	position	position	NN
cord-256444-grw5s2pf	95	12	of	of	IN
cord-256444-grw5s2pf	95	13	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	95	14	protein	protein	NN
cord-256444-grw5s2pf	95	15	genes	gene	NNS
cord-256444-grw5s2pf	95	16	.	.	.
cord-256444-grw5s2pf	96	1	The	the	DT
cord-256444-grw5s2pf	96	2	polymerase	polymerase	NN
cord-256444-grw5s2pf	96	3	genes	gene	NNS
cord-256444-grw5s2pf	96	4	encode	encode	VBP
cord-256444-grw5s2pf	96	5	two	two	CD
cord-256444-grw5s2pf	96	6	ORFs	orf	NNS
cord-256444-grw5s2pf	96	7	,	,	,
cord-256444-grw5s2pf	96	8	l	l	NNP
cord-256444-grw5s2pf	96	9	a	a	NNP
cord-256444-grw5s2pf	96	10	and	and	CC
cord-256444-grw5s2pf	96	11	lb	lb	NN
cord-256444-grw5s2pf	96	12	,	,	,
cord-256444-grw5s2pf	96	13	which	which	WDT
cord-256444-grw5s2pf	96	14	overlap	overlap	VBP
cord-256444-grw5s2pf	96	15	.	.	.
cord-256444-grw5s2pf	97	1	L	l	NN
cord-256444-grw5s2pf	97	2	,	,	,
cord-256444-grw5s2pf	97	3	leader	leader	NN
cord-256444-grw5s2pf	97	4	sequence	sequence	NN
cord-256444-grw5s2pf	97	5	;	;	:
cord-256444-grw5s2pf	97	6	HE	he	PRP
cord-256444-grw5s2pf	97	7	,	,	,
cord-256444-grw5s2pf	97	8	hemagglutinin	hemagglutinin	NN
cord-256444-grw5s2pf	97	9	-	-	HYPH
cord-256444-grw5s2pf	97	10	esterase	esterase	NN
cord-256444-grw5s2pf	97	11	;	;	:
cord-256444-grw5s2pf	97	12	S	s	NN
cord-256444-grw5s2pf	97	13	,	,	,
cord-256444-grw5s2pf	97	14	spike	spike	NN
cord-256444-grw5s2pf	97	15	;	;	:
cord-256444-grw5s2pf	97	16	E	e	NN
cord-256444-grw5s2pf	97	17	,	,	,
cord-256444-grw5s2pf	97	18	small	small	JJ
cord-256444-grw5s2pf	97	19	membrane	membrane	NN
cord-256444-grw5s2pf	97	20	protein	protein	NN
cord-256444-grw5s2pf	97	21	;	;	:
cord-256444-grw5s2pf	97	22	M	M	NNP
cord-256444-grw5s2pf	97	23	,	,	,
cord-256444-grw5s2pf	97	24	integral	integral	JJ
cord-256444-grw5s2pf	97	25	membrane	membrane	NN
cord-256444-grw5s2pf	97	26	protein	protein	NN
cord-256444-grw5s2pf	97	27	;	;	:
cord-256444-grw5s2pf	97	28	N	N	NNP
cord-256444-grw5s2pf	97	29	,	,	,
cord-256444-grw5s2pf	97	30	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	97	31	protein	protein	NN
cord-256444-grw5s2pf	97	32	;	;	.
cord-256444-grw5s2pf	98	1	An	an	DT
cord-256444-grw5s2pf	98	2	,	,	,
cord-256444-grw5s2pf	98	3	poly(A	poly(a	JJ
cord-256444-grw5s2pf	98	4	)	)	-RRB-
cord-256444-grw5s2pf	98	5	tail	tail	NN
cord-256444-grw5s2pf	98	6	;	;	:
cord-256444-grw5s2pf	98	7	G	g	NN
cord-256444-grw5s2pf	98	8	,	,	,
cord-256444-grw5s2pf	98	9	and	and	CC
cord-256444-grw5s2pf	98	10	GL	GL	NNP
cord-256444-grw5s2pf	98	11	,	,	,
cord-256444-grw5s2pf	98	12	small	small	JJ
cord-256444-grw5s2pf	98	13	and	and	CC
cord-256444-grw5s2pf	98	14	large	large	JJ
cord-256444-grw5s2pf	98	15	glycoproteins	glycoprotein	NNS
cord-256444-grw5s2pf	98	16	,	,	,
cord-256444-grw5s2pf	98	17	respectively	respectively	RB
cord-256444-grw5s2pf	98	18	.	.	.
cord-256444-grw5s2pf	99	1	Risco	Risco	NNP
cord-256444-grw5s2pf	99	2	et	et	NNP
cord-256444-grw5s2pf	99	3	al	al	NNP
cord-256444-grw5s2pf	99	4	.	.	.
cord-256444-grw5s2pf	100	1	(	(	-LRB-
cord-256444-grw5s2pf	100	2	1996	1996	CD
cord-256444-grw5s2pf	100	3	)	)	-RRB-
cord-256444-grw5s2pf	100	4	for	for	IN
cord-256444-grw5s2pf	100	5	TGEV	TGEV	NNP
cord-256444-grw5s2pf	100	6	.	.	.
cord-256444-grw5s2pf	101	1	This	this	DT
cord-256444-grw5s2pf	101	2	model	model	NN
cord-256444-grw5s2pf	101	3	illustrates	illustrate	VBZ
cord-256444-grw5s2pf	101	4	the	the	DT
cord-256444-grw5s2pf	101	5	observation	observation	NN
cord-256444-grw5s2pf	101	6	that	that	IN
cord-256444-grw5s2pf	101	7	internal	internal	JJ
cord-256444-grw5s2pf	101	8	cores	core	NNS
cord-256444-grw5s2pf	101	9	(	(	-LRB-
cord-256444-grw5s2pf	101	10	IC	IC	NNP
cord-256444-grw5s2pf	101	11	)	)	-RRB-
cord-256444-grw5s2pf	101	12	,	,	,
cord-256444-grw5s2pf	101	13	possibly	possibly	RB
cord-256444-grw5s2pf	101	14	icosahedral	icosahedral	JJ
cord-256444-grw5s2pf	101	15	,	,	,
cord-256444-grw5s2pf	101	16	were	be	VBD
cord-256444-grw5s2pf	101	17	observed	observe	VBN
cord-256444-grw5s2pf	101	18	inside	inside	IN
cord-256444-grw5s2pf	101	19	virions	virion	NNS
cord-256444-grw5s2pf	101	20	of	of	IN
cord-256444-grw5s2pf	101	21	TGEV	TGEV	NNS
cord-256444-grw5s2pf	101	22	.	.	.
cord-256444-grw5s2pf	102	1	The	the	DT
cord-256444-grw5s2pf	102	2	cores	core	NNS
cord-256444-grw5s2pf	102	3	comprise	comprise	VBP
cord-256444-grw5s2pf	102	4	the	the	DT
cord-256444-grw5s2pf	102	5	helical	helical	JJ
cord-256444-grw5s2pf	102	6	ribonucleoprotein	ribonucleoprotein	NN
cord-256444-grw5s2pf	102	7	(	(	-LRB-
cord-256444-grw5s2pf	102	8	NC	NC	NNP
cord-256444-grw5s2pf	102	9	)	)	-RRB-
cord-256444-grw5s2pf	102	10	(	(	-LRB-
cord-256444-grw5s2pf	102	11	genome	genome	NNP
cord-256444-grw5s2pf	102	12	RNA	RNA	NNP
cord-256444-grw5s2pf	102	13	+	+	CC
cord-256444-grw5s2pf	102	14	N	n	CD
cord-256444-grw5s2pf	102	15	protein	protein	NN
cord-256444-grw5s2pf	102	16	)	)	-RRB-
cord-256444-grw5s2pf	102	17	and	and	CC
cord-256444-grw5s2pf	102	18	the	the	DT
cord-256444-grw5s2pf	102	19	M	M	NNP
cord-256444-grw5s2pf	102	20	protein	protein	NN
cord-256444-grw5s2pf	102	21	.	.	.
cord-256444-grw5s2pf	103	1	Reproduced	reproduce	VBN
cord-256444-grw5s2pf	103	2	with	with	IN
cord-256444-grw5s2pf	103	3	permission	permission	NN
cord-256444-grw5s2pf	103	4	from	from	IN
cord-256444-grw5s2pf	103	5	Risco	Risco	NNP
cord-256444-grw5s2pf	103	6	et	et	NNP
cord-256444-grw5s2pf	103	7	al	al	NNP
cord-256444-grw5s2pf	103	8	.	.	.
cord-256444-grw5s2pf	104	1	(	(	-LRB-
cord-256444-grw5s2pf	104	2	1996	1996	CD
cord-256444-grw5s2pf	104	3	)	)	-RRB-
cord-256444-grw5s2pf	104	4	.	.	.
cord-256444-grw5s2pf	105	1	cleaved	cleave	VBN
cord-256444-grw5s2pf	105	2	if	if	IN
cord-256444-grw5s2pf	105	3	trypsin	trypsin	NN
cord-256444-grw5s2pf	105	4	is	be	VBZ
cord-256444-grw5s2pf	105	5	present	present	JJ
cord-256444-grw5s2pf	105	6	(	(	-LRB-
cord-256444-grw5s2pf	105	7	Hogue	Hogue	NNP
cord-256444-grw5s2pf	105	8	and	and	CC
cord-256444-grw5s2pf	105	9	Brian	Brian	NNP
cord-256444-grw5s2pf	105	10	,	,	,
cord-256444-grw5s2pf	105	11	1986	1986	CD
cord-256444-grw5s2pf	105	12	)	)	-RRB-
cord-256444-grw5s2pf	105	13	.	.	.
cord-256444-grw5s2pf	106	1	The	the	DT
cord-256444-grw5s2pf	106	2	extent	extent	NN
cord-256444-grw5s2pf	106	3	of	of	IN
cord-256444-grw5s2pf	106	4	S	s	NN
cord-256444-grw5s2pf	106	5	cleavage	cleavage	NN
cord-256444-grw5s2pf	106	6	depends	depend	VBZ
cord-256444-grw5s2pf	106	7	on	on	IN
cord-256444-grw5s2pf	106	8	the	the	DT
cord-256444-grw5s2pf	106	9	cell	cell	NN
cord-256444-grw5s2pf	106	10	type	type	NN
cord-256444-grw5s2pf	106	11	(	(	-LRB-
cord-256444-grw5s2pf	106	12	Frana	Frana	NNP
cord-256444-grw5s2pf	106	13	et	et	FW
cord-256444-grw5s2pf	106	14	al	al	NNP
cord-256444-grw5s2pf	106	15	.	.	NNP
cord-256444-grw5s2pf	106	16	,	,	,
cord-256444-grw5s2pf	106	17	1985	1985	CD
cord-256444-grw5s2pf	106	18	)	)	-RRB-
cord-256444-grw5s2pf	106	19	.	.	.
cord-256444-grw5s2pf	107	1	Cleavage	cleavage	NN
cord-256444-grw5s2pf	107	2	generates	generate	VBZ
cord-256444-grw5s2pf	107	3	two	two	CD
cord-256444-grw5s2pf	107	4	glycopolypeptides	glycopolypeptide	NNS
cord-256444-grw5s2pf	107	5	,	,	,
cord-256444-grw5s2pf	107	6	N	n	CD
cord-256444-grw5s2pf	107	7	-	-	HYPH
cord-256444-grw5s2pf	107	8	terminal	terminal	NN
cord-256444-grw5s2pf	107	9	S1	S1	NNP
cord-256444-grw5s2pf	107	10	and	and	CC
cord-256444-grw5s2pf	107	11	C	C	NNP
cord-256444-grw5s2pf	107	12	-	-	HYPH
cord-256444-grw5s2pf	107	13	terminal	terminal	NN
cord-256444-grw5s2pf	107	14	S2	s2	NN
cord-256444-grw5s2pf	107	15	,	,	,
cord-256444-grw5s2pf	107	16	the	the	DT
cord-256444-grw5s2pf	107	17	latter	latter	JJ
cord-256444-grw5s2pf	107	18	being	be	VBG
cord-256444-grw5s2pf	107	19	acylated	acylate	VBN
cord-256444-grw5s2pf	107	20	.	.	.
cord-256444-grw5s2pf	108	1	S1	s1	NN
cord-256444-grw5s2pf	108	2	is	be	VBZ
cord-256444-grw5s2pf	108	3	probably	probably	RB
cord-256444-grw5s2pf	108	4	linked	link	VBN
cord-256444-grw5s2pf	108	5	to	to	IN
cord-256444-grw5s2pf	108	6	the	the	DT
cord-256444-grw5s2pf	108	7	S2	s2	NN
cord-256444-grw5s2pf	108	8	subunits	subunit	NNS
cord-256444-grw5s2pf	108	9	by	by	IN
cord-256444-grw5s2pf	108	10	noncovalent	noncovalent	NNP
cord-256444-grw5s2pf	108	11	linkage	linkage	NN
cord-256444-grw5s2pf	108	12	:	:	:
cord-256444-grw5s2pf	108	13	trypsin	trypsin	NN
cord-256444-grw5s2pf	108	14	treatment	treatment	NN
cord-256444-grw5s2pf	108	15	of	of	IN
cord-256444-grw5s2pf	108	16	MHV	MHV	NNP
cord-256444-grw5s2pf	108	17	virions	virion	NNS
cord-256444-grw5s2pf	108	18	caused	cause	VBD
cord-256444-grw5s2pf	108	19	cleavage	cleavage	NN
cord-256444-grw5s2pf	108	20	of	of	IN
cord-256444-grw5s2pf	108	21	all	all	DT
cord-256444-grw5s2pf	108	22	S	s	NN
cord-256444-grw5s2pf	108	23	proteins	protein	NNS
cord-256444-grw5s2pf	108	24	without	without	IN
cord-256444-grw5s2pf	108	25	disrupting	disrupt	VBG
cord-256444-grw5s2pf	108	26	the	the	DT
cord-256444-grw5s2pf	108	27	spikes	spike	NNS
cord-256444-grw5s2pf	108	28	;	;	:
cord-256444-grw5s2pf	108	29	however	however	RB
cord-256444-grw5s2pf	108	30	,	,	,
cord-256444-grw5s2pf	108	31	S1	S1	NNP
cord-256444-grw5s2pf	108	32	can	can	MD
cord-256444-grw5s2pf	108	33	be	be	VB
cord-256444-grw5s2pf	108	34	released	release	VBN
cord-256444-grw5s2pf	108	35	from	from	IN
cord-256444-grw5s2pf	108	36	virion	virion	NN
cord-256444-grw5s2pf	108	37	by	by	IN
cord-256444-grw5s2pf	108	38	either	either	CC
cord-256444-grw5s2pf	108	39	urea	urea	NN
cord-256444-grw5s2pf	108	40	or	or	CC
cord-256444-grw5s2pf	108	41	mild	mild	JJ
cord-256444-grw5s2pf	108	42	alkali	alkali	JJ
cord-256444-grw5s2pf	108	43	treatment	treatment	NN
cord-256444-grw5s2pf	108	44	(	(	-LRB-
cord-256444-grw5s2pf	108	45	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	108	46	and	and	CC
cord-256444-grw5s2pf	108	47	Davis	Davis	NNP
cord-256444-grw5s2pf	108	48	,	,	,
cord-256444-grw5s2pf	108	49	1986	1986	CD
cord-256444-grw5s2pf	108	50	;	;	:
cord-256444-grw5s2pf	108	51	Weismiller	Weismiller	NNP
cord-256444-grw5s2pf	108	52	et	et	NNP
cord-256444-grw5s2pf	108	53	al	al	NNP
cord-256444-grw5s2pf	108	54	.	.	NNP
cord-256444-grw5s2pf	108	55	,	,	,
cord-256444-grw5s2pf	108	56	1990	1990	CD
cord-256444-grw5s2pf	108	57	)	)	-RRB-
cord-256444-grw5s2pf	108	58	.	.	.
cord-256444-grw5s2pf	109	1	Among	among	IN
cord-256444-grw5s2pf	109	2	the	the	DT
cord-256444-grw5s2pf	109	3	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	109	4	genus	genus	NN
cord-256444-grw5s2pf	109	5	as	as	IN
cord-256444-grw5s2pf	109	6	a	a	DT
cord-256444-grw5s2pf	109	7	whole	whole	NN
cord-256444-grw5s2pf	109	8	,	,	,
cord-256444-grw5s2pf	109	9	the	the	DT
cord-256444-grw5s2pf	109	10	S2	S2	NNP
cord-256444-grw5s2pf	109	11	polypeptide	polypeptide	NN
cord-256444-grw5s2pf	109	12	is	be	VBZ
cord-256444-grw5s2pf	109	13	much	much	RB
cord-256444-grw5s2pf	109	14	more	more	RBR
cord-256444-grw5s2pf	109	15	conserved	conserved	JJ
cord-256444-grw5s2pf	109	16	than	than	IN
cord-256444-grw5s2pf	109	17	S1	S1	NNP
cord-256444-grw5s2pf	109	18	.	.	.
cord-256444-grw5s2pf	110	1	Regions	region	NNS
cord-256444-grw5s2pf	110	2	of	of	IN
cord-256444-grw5s2pf	110	3	up	up	IN
cord-256444-grw5s2pf	110	4	to	to	TO
cord-256444-grw5s2pf	110	5	30	30	CD
cord-256444-grw5s2pf	110	6	%	%	NN
cord-256444-grw5s2pf	110	7	amino	amino	NN
cord-256444-grw5s2pf	110	8	acid	acid	NN
cord-256444-grw5s2pf	110	9	identity	identity	NN
cord-256444-grw5s2pf	110	10	(	(	-LRB-
cord-256444-grw5s2pf	110	11	particularly	particularly	RB
cord-256444-grw5s2pf	110	12	in	in	IN
cord-256444-grw5s2pf	110	13	the	the	DT
cord-256444-grw5s2pf	110	14	transmembrane	transmembrane	NN
cord-256444-grw5s2pf	110	15	domain	domain	NN
cord-256444-grw5s2pf	110	16	)	)	-RRB-
cord-256444-grw5s2pf	110	17	exist	exist	VBP
cord-256444-grw5s2pf	110	18	between	between	IN
cord-256444-grw5s2pf	110	19	the	the	DT
cord-256444-grw5s2pf	110	20	S2	s2	NN
cord-256444-grw5s2pf	110	21	polypeptides	polypeptide	NNS
cord-256444-grw5s2pf	110	22	of	of	IN
cord-256444-grw5s2pf	110	23	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	110	24	in	in	IN
cord-256444-grw5s2pf	110	25	the	the	DT
cord-256444-grw5s2pf	110	26	different	different	JJ
cord-256444-grw5s2pf	110	27	antigenic	antigenic	JJ
cord-256444-grw5s2pf	110	28	groups	group	NNS
cord-256444-grw5s2pf	110	29	,	,	,
cord-256444-grw5s2pf	110	30	whereas	whereas	RB
cord-256444-grw5s2pf	110	31	and	and	CC
cord-256444-grw5s2pf	110	32	(	(	-LRB-
cord-256444-grw5s2pf	110	33	b	b	NN
cord-256444-grw5s2pf	110	34	)	)	-RRB-
cord-256444-grw5s2pf	110	35	(	(	-LRB-
cord-256444-grw5s2pf	110	36	Schmidtet	Schmidtet	NNP
cord-256444-grw5s2pf	110	37	al	al	NNP
cord-256444-grw5s2pf	110	38	.	.	NNP
cord-256444-grw5s2pf	110	39	,	,	,
cord-256444-grw5s2pf	110	40	1987	1987	CD
cord-256444-grw5s2pf	110	41	)	)	-RRB-
cord-256444-grw5s2pf	110	42	.	.	.
cord-256444-grw5s2pf	111	1	The	the	DT
cord-256444-grw5s2pf	111	2	amino	amino	NN
cord-256444-grw5s2pf	111	3	acid	acid	NN
cord-256444-grw5s2pf	111	4	numbering	numbering	NN
cord-256444-grw5s2pf	111	5	has	have	VBZ
cord-256444-grw5s2pf	111	6	been	be	VBN
cord-256444-grw5s2pf	111	7	normalized	normalize	VBN
cord-256444-grw5s2pf	111	8	with	with	IN
cord-256444-grw5s2pf	111	9	respect	respect	NN
cord-256444-grw5s2pf	111	10	to	to	IN
cord-256444-grw5s2pf	111	11	that	that	DT
cord-256444-grw5s2pf	111	12	of	of	IN
cord-256444-grw5s2pf	111	13	the	the	DT
cord-256444-grw5s2pf	111	14	longest	long	RBS
cord-256444-grw5s2pf	111	15	known	know	VBN
cord-256444-grw5s2pf	111	16	MHV	MHV	NNP
cord-256444-grw5s2pf	111	17	S	S	NNP
cord-256444-grw5s2pf	111	18	protein	protein	NN
cord-256444-grw5s2pf	111	19	,	,	,
cord-256444-grw5s2pf	111	20	that	that	DT
cord-256444-grw5s2pf	111	21	of	of	IN
cord-256444-grw5s2pf	111	22	MHV4	MHV4	NNP
cord-256444-grw5s2pf	111	23	(	(	-LRB-
cord-256444-grw5s2pf	111	24	JHM	JHM	NNP
cord-256444-grw5s2pf	111	25	)	)	-RRB-
cord-256444-grw5s2pf	112	1	(	(	-LRB-
cord-256444-grw5s2pf	112	2	S	S	NNP
cord-256444-grw5s2pf	112	3	.	.	.
cord-256444-grw5s2pf	113	1	E.	E.	NNP
cord-256444-grw5s2pf	113	2	.	.	.
cord-256444-grw5s2pf	114	1	(	(	-LRB-
cord-256444-grw5s2pf	114	2	a	a	LS
cord-256444-grw5s2pf	114	3	)	)	-RRB-
cord-256444-grw5s2pf	115	1	The	the	DT
cord-256444-grw5s2pf	115	2	protein	protein	NN
cord-256444-grw5s2pf	115	3	has	have	VBZ
cord-256444-grw5s2pf	115	4	an	an	DT
cord-256444-grw5s2pf	115	5	amino	amino	NN
cord-256444-grw5s2pf	115	6	-	-	HYPH
cord-256444-grw5s2pf	115	7	terminal	terminal	NN
cord-256444-grw5s2pf	115	8	signal	signal	NN
cord-256444-grw5s2pf	115	9	peptide	peptide	NN
cord-256444-grw5s2pf	115	10	(	(	-LRB-
cord-256444-grw5s2pf	115	11	sp	sp	NNP
cord-256444-grw5s2pf	115	12	)	)	-RRB-
cord-256444-grw5s2pf	115	13	and	and	CC
cord-256444-grw5s2pf	115	14	a	a	DT
cord-256444-grw5s2pf	115	15	transmembrane	transmembrane	NN
cord-256444-grw5s2pf	115	16	(	(	-LRB-
cord-256444-grw5s2pf	115	17	TM	TM	NNP
cord-256444-grw5s2pf	115	18	)	)	-RRB-
cord-256444-grw5s2pf	115	19	sequence	sequence	NN
cord-256444-grw5s2pf	115	20	near	near	IN
cord-256444-grw5s2pf	115	21	the	the	DT
cord-256444-grw5s2pf	115	22	C	C	NNP
cord-256444-grw5s2pf	115	23	terminus	terminus	NN
cord-256444-grw5s2pf	115	24	.	.	.
cord-256444-grw5s2pf	116	1	The	the	DT
cord-256444-grw5s2pf	116	2	glycosylated	glycosylated	JJ
cord-256444-grw5s2pf	116	3	propolypeptide	propolypeptide	NN
cord-256444-grw5s2pf	116	4	is	be	VBZ
cord-256444-grw5s2pf	116	5	cleaved	cleave	VBN
cord-256444-grw5s2pf	116	6	a	a	DT
cord-256444-grw5s2pf	116	7	t	t	NN
cord-256444-grw5s2pf	116	8	a	a	DT
cord-256444-grw5s2pf	116	9	basic	basic	JJ
cord-256444-grw5s2pf	116	10	connecting	connect	VBG
cord-256444-grw5s2pf	116	11	peptide	peptide	NN
cord-256444-grw5s2pf	116	12	(	(	-LRB-
cord-256444-grw5s2pf	116	13	cp	cp	NN
cord-256444-grw5s2pf	116	14	)	)	-RRB-
cord-256444-grw5s2pf	116	15	to	to	TO
cord-256444-grw5s2pf	116	16	yield	yield	VB
cord-256444-grw5s2pf	116	17	glycopolypeptides	glycopolypeptide	NNS
cord-256444-grw5s2pf	116	18	S1	S1	NNP
cord-256444-grw5s2pf	116	19	and	and	CC
cord-256444-grw5s2pf	116	20	S2	S2	NNP
cord-256444-grw5s2pf	116	21	.	.	.
cord-256444-grw5s2pf	117	1	The	the	DT
cord-256444-grw5s2pf	117	2	locations	location	NNS
cord-256444-grw5s2pf	117	3	shown	show	VBN
cord-256444-grw5s2pf	117	4	are	be	VBP
cord-256444-grw5s2pf	117	5	those	those	DT
cord-256444-grw5s2pf	117	6	of	of	IN
cord-256444-grw5s2pf	117	7	three	three	CD
cord-256444-grw5s2pf	117	8	mutations	mutation	NNS
cord-256444-grw5s2pf	117	9	present	present	JJ
cord-256444-grw5s2pf	117	10	in	in	IN
cord-256444-grw5s2pf	117	11	mutants	mutant	NNS
cord-256444-grw5s2pf	117	12	of	of	IN
cord-256444-grw5s2pf	117	13	MHV4	MHV4	NNP
cord-256444-grw5s2pf	117	14	recovered	recover	VBD
cord-256444-grw5s2pf	117	15	from	from	IN
cord-256444-grw5s2pf	117	16	a	a	DT
cord-256444-grw5s2pf	117	17	persistently	persistently	RB
cord-256444-grw5s2pf	117	18	infected	infect	VBN
cord-256444-grw5s2pf	117	19	neural	neural	JJ
cord-256444-grw5s2pf	117	20	cell	cell	NN
cord-256444-grw5s2pf	117	21	line	line	NN
cord-256444-grw5s2pf	117	22	,	,	,
cord-256444-grw5s2pf	117	23	the	the	DT
cord-256444-grw5s2pf	117	24	mutants	mutant	NNS
cord-256444-grw5s2pf	117	25	requiring	require	VBG
cord-256444-grw5s2pf	117	26	a	a	DT
cord-256444-grw5s2pf	117	27	pH	ph	NN
cord-256444-grw5s2pf	117	28	of	of	IN
cord-256444-grw5s2pf	117	29	5.5	5.5	CD
cord-256444-grw5s2pf	117	30	-	-	SYM
cord-256444-grw5s2pf	117	31	6.0	6.0	CD
cord-256444-grw5s2pf	117	32	for	for	IN
cord-256444-grw5s2pf	117	33	membrane	membrane	NN
cord-256444-grw5s2pf	117	34	fusion	fusion	NN
cord-256444-grw5s2pf	118	1	(	(	-LRB-
cord-256444-grw5s2pf	118	2	Gallagher	Gallagher	NNP
cord-256444-grw5s2pf	118	3	et	et	NNP
cord-256444-grw5s2pf	118	4	al	al	NNP
cord-256444-grw5s2pf	118	5	.	.	NNP
cord-256444-grw5s2pf	118	6	,	,	,
cord-256444-grw5s2pf	118	7	1991	1991	CD
cord-256444-grw5s2pf	118	8	)	)	-RRB-
cord-256444-grw5s2pf	118	9	.	.	.
cord-256444-grw5s2pf	119	1	(	(	-LRB-
cord-256444-grw5s2pf	119	2	b	b	NN
cord-256444-grw5s2pf	119	3	)	)	-RRB-
cord-256444-grw5s2pf	119	4	S	s	NN
cord-256444-grw5s2pf	119	5	of	of	IN
cord-256444-grw5s2pf	119	6	another	another	DT
cord-256444-grw5s2pf	119	7	MHV	MHV	NNP
cord-256444-grw5s2pf	119	8	-	-	HYPH
cord-256444-grw5s2pf	119	9	JHM	JHM	NNP
cord-256444-grw5s2pf	120	1	(	(	-LRB-
cord-256444-grw5s2pf	120	2	Schmidt	Schmidt	NNP
cord-256444-grw5s2pf	120	3	et	et	NNP
cord-256444-grw5s2pf	120	4	al	al	NNP
cord-256444-grw5s2pf	120	5	.	.	NNP
cord-256444-grw5s2pf	120	6	,	,	,
cord-256444-grw5s2pf	120	7	1987	1987	CD
cord-256444-grw5s2pf	120	8	)	)	-RRB-
cord-256444-grw5s2pf	120	9	,	,	,
cord-256444-grw5s2pf	120	10	which	which	WDT
cord-256444-grw5s2pf	120	11	has	have	VBZ
cord-256444-grw5s2pf	120	12	a	a	DT
cord-256444-grw5s2pf	120	13	141-amino	141-amino	CD
cord-256444-grw5s2pf	120	14	acid	acid	NN
cord-256444-grw5s2pf	120	15	deletion	deletion	NN
cord-256444-grw5s2pf	120	16	with	with	IN
cord-256444-grw5s2pf	120	17	respect	respect	NN
cord-256444-grw5s2pf	120	18	to	to	IN
cord-256444-grw5s2pf	120	19	(	(	-LRB-
cord-256444-grw5s2pf	120	20	a	a	NN
cord-256444-grw5s2pf	120	21	)	)	-RRB-
cord-256444-grw5s2pf	120	22	.	.	.
cord-256444-grw5s2pf	121	1	Bacterial	bacterial	JJ
cord-256444-grw5s2pf	121	2	expression	expression	NN
cord-256444-grw5s2pf	121	3	products	product	NNS
cord-256444-grw5s2pf	121	4	containing	contain	VBG
cord-256444-grw5s2pf	121	5	residues	residue	NNS
cord-256444-grw5s2pf	121	6	33	33	CD
cord-256444-grw5s2pf	121	7	-	-	SYM
cord-256444-grw5s2pf	121	8	40	40	CD
cord-256444-grw5s2pf	121	9	and	and	CC
cord-256444-grw5s2pf	121	10	1264	1264	CD
cord-256444-grw5s2pf	121	11	-	-	HYPH
cord-256444-grw5s2pf	121	12	1276	1276	CD
cord-256444-grw5s2pf	121	13	bound	bind	VBN
cord-256444-grw5s2pf	121	14	MAb	MAb	NNS
cord-256444-grw5s2pf	121	15	11F	11f	CD
cord-256444-grw5s2pf	121	16	and	and	CC
cord-256444-grw5s2pf	121	17	10	10	CD
cord-256444-grw5s2pf	121	18	G	g	NN
cord-256444-grw5s2pf	121	19	,	,	,
cord-256444-grw5s2pf	121	20	respectively	respectively	RB
cord-256444-grw5s2pf	121	21	,	,	,
cord-256444-grw5s2pf	121	22	both	both	DT
cord-256444-grw5s2pf	121	23	of	of	IN
cord-256444-grw5s2pf	121	24	which	which	WDT
cord-256444-grw5s2pf	121	25	neutralize	neutralize	VBP
cord-256444-grw5s2pf	121	26	virus	virus	NN
cord-256444-grw5s2pf	121	27	infectivity	infectivity	NN
cord-256444-grw5s2pf	121	28	and	and	CC
cord-256444-grw5s2pf	121	29	inhibit	inhibit	VB
cord-256444-grw5s2pf	121	30	membrane	membrane	NN
cord-256444-grw5s2pf	121	31	fusion	fusion	NN
cord-256444-grw5s2pf	121	32	.	.	.
cord-256444-grw5s2pf	122	1	The	the	DT
cord-256444-grw5s2pf	122	2	arrow	arrow	NN
cord-256444-grw5s2pf	122	3	indicates	indicate	VBZ
cord-256444-grw5s2pf	122	4	the	the	DT
cord-256444-grw5s2pf	122	5	positions	position	NNS
cord-256444-grw5s2pf	122	6	of	of	IN
cord-256444-grw5s2pf	122	7	amino	amino	NN
cord-256444-grw5s2pf	122	8	acid	acid	NN
cord-256444-grw5s2pf	122	9	substitutions	substitution	NNS
cord-256444-grw5s2pf	122	10	in	in	IN
cord-256444-grw5s2pf	122	11	JHM	JHM	NNP
cord-256444-grw5s2pf	122	12	MAb	MAb	NNS
cord-256444-grw5s2pf	122	13	11F	11f	CD
cord-256444-grw5s2pf	122	14	-	-	HYPH
cord-256444-grw5s2pf	122	15	resistant	resistant	JJ
cord-256444-grw5s2pf	122	16	mutants	mutant	NNS
cord-256444-grw5s2pf	122	17	(	(	-LRB-
cord-256444-grw5s2pf	122	18	Grosse	Grosse	NNP
cord-256444-grw5s2pf	122	19	and	and	CC
cord-256444-grw5s2pf	122	20	Siddell	Siddell	NNP
cord-256444-grw5s2pf	122	21	,	,	,
cord-256444-grw5s2pf	122	22	1994	1994	CD
cord-256444-grw5s2pf	122	23	)	)	-RRB-
cord-256444-grw5s2pf	122	24	.	.	.
cord-256444-grw5s2pf	123	1	A	a	DT
cord-256444-grw5s2pf	123	2	peptide	peptide	NN
cord-256444-grw5s2pf	123	3	comprising	comprise	VBG
cord-256444-grw5s2pf	123	4	residues	residue	NNS
cord-256444-grw5s2pf	123	5	900	900	CD
cord-256444-grw5s2pf	123	6	-	-	HYPH
cord-256444-grw5s2pf	123	7	908	908	CD
cord-256444-grw5s2pf	123	8	bound	bind	VBD
cord-256444-grw5s2pf	123	9	another	another	DT
cord-256444-grw5s2pf	123	10	MAb	MAb	NNS
cord-256444-grw5s2pf	123	11	that	that	WDT
cord-256444-grw5s2pf	123	12	neutralized	neutralize	VBD
cord-256444-grw5s2pf	123	13	virus	virus	NN
cord-256444-grw5s2pf	123	14	and	and	CC
cord-256444-grw5s2pf	123	15	inhibited	inhibited	JJ
cord-256444-grw5s2pf	123	16	fusion	fusion	NN
cord-256444-grw5s2pf	124	1	(	(	-LRB-
cord-256444-grw5s2pf	124	2	Luytjes	Luytjes	NNP
cord-256444-grw5s2pf	124	3	et	et	NNP
cord-256444-grw5s2pf	124	4	al	al	NNP
cord-256444-grw5s2pf	124	5	.	.	NNP
cord-256444-grw5s2pf	124	6	,	,	,
cord-256444-grw5s2pf	124	7	1989	1989	CD
cord-256444-grw5s2pf	124	8	)	)	-RRB-
cord-256444-grw5s2pf	124	9	.	.	.
cord-256444-grw5s2pf	125	1	there	there	EX
cord-256444-grw5s2pf	125	2	is	be	VBZ
cord-256444-grw5s2pf	125	3	almost	almost	RB
cord-256444-grw5s2pf	125	4	no	no	DT
cord-256444-grw5s2pf	125	5	conservation	conservation	NN
cord-256444-grw5s2pf	125	6	of	of	IN
cord-256444-grw5s2pf	125	7	the	the	DT
cord-256444-grw5s2pf	125	8	S1	s1	NN
cord-256444-grw5s2pf	125	9	sequence	sequence	NN
cord-256444-grw5s2pf	125	10	.	.	.
cord-256444-grw5s2pf	126	1	Furthermore	furthermore	RB
cord-256444-grw5s2pf	126	2	,	,	,
cord-256444-grw5s2pf	126	3	comparison	comparison	NN
cord-256444-grw5s2pf	126	4	of	of	IN
cord-256444-grw5s2pf	126	5	S1	s1	NN
cord-256444-grw5s2pf	126	6	sequences	sequence	NNS
cord-256444-grw5s2pf	126	7	among	among	IN
cord-256444-grw5s2pf	126	8	strains	strain	NNS
cord-256444-grw5s2pf	126	9	of	of	IN
cord-256444-grw5s2pf	126	10	a	a	DT
cord-256444-grw5s2pf	126	11	given	give	VBN
cord-256444-grw5s2pf	126	12	species	species	NN
cord-256444-grw5s2pf	126	13	,	,	,
cord-256444-grw5s2pf	126	14	or	or	CC
cord-256444-grw5s2pf	126	15	between	between	IN
cord-256444-grw5s2pf	126	16	species	specie	NNS
cord-256444-grw5s2pf	126	17	of	of	IN
cord-256444-grw5s2pf	126	18	a	a	DT
cord-256444-grw5s2pf	126	19	given	give	VBN
cord-256444-grw5s2pf	126	20	group	group	NN
cord-256444-grw5s2pf	126	21	,	,	,
cord-256444-grw5s2pf	126	22	reveals	reveal	VBZ
cord-256444-grw5s2pf	126	23	hypervariable	hypervariable	JJ
cord-256444-grw5s2pf	126	24	regions	region	NNS
cord-256444-grw5s2pf	126	25	,	,	,
cord-256444-grw5s2pf	126	26	which	which	WDT
cord-256444-grw5s2pf	126	27	include	include	VBP
cord-256444-grw5s2pf	126	28	frequent	frequent	JJ
cord-256444-grw5s2pf	126	29	deletions	deletion	NNS
cord-256444-grw5s2pf	126	30	,	,	,
cord-256444-grw5s2pf	126	31	mutations	mutation	NNS
cord-256444-grw5s2pf	126	32	,	,	,
cord-256444-grw5s2pf	126	33	or	or	CC
cord-256444-grw5s2pf	126	34	recombination	recombination	NN
cord-256444-grw5s2pf	126	35	(	(	-LRB-
cord-256444-grw5s2pf	126	36	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	126	37	et	et	NNP
cord-256444-grw5s2pf	126	38	al	al	NNP
cord-256444-grw5s2pf	126	39	.	.	NNP
cord-256444-grw5s2pf	126	40	,	,	,
cord-256444-grw5s2pf	126	41	1988	1988	CD
cord-256444-grw5s2pf	126	42	;	;	:
cord-256444-grw5s2pf	126	43	S.	S.	NNP
cord-256444-grw5s2pf	126	44	E.	E.	NNP
cord-256444-grw5s2pf	126	45	Parker	Parker	NNP
cord-256444-grw5s2pf	126	46	et	et	NNP
cord-256444-grw5s2pf	126	47	al	al	NNP
cord-256444-grw5s2pf	126	48	.	.	NNP
cord-256444-grw5s2pf	126	49	,	,	,
cord-256444-grw5s2pf	126	50	1989	1989	CD
cord-256444-grw5s2pf	126	51	;	;	:
cord-256444-grw5s2pf	126	52	Banner	Banner	NNP
cord-256444-grw5s2pf	126	53	et	et	FW
cord-256444-grw5s2pf	126	54	al	al	NNP
cord-256444-grw5s2pf	126	55	.	.	NNP
cord-256444-grw5s2pf	126	56	,	,	,
cord-256444-grw5s2pf	126	57	1990	1990	CD
cord-256444-grw5s2pf	126	58	;	;	:
cord-256444-grw5s2pf	126	59	Gallagher	Gallagher	NNP
cord-256444-grw5s2pf	126	60	et	et	NNP
cord-256444-grw5s2pf	126	61	al	al	NNP
cord-256444-grw5s2pf	126	62	.	.	NNP
cord-256444-grw5s2pf	126	63	,	,	,
cord-256444-grw5s2pf	126	64	19901	19901	CD
cord-256444-grw5s2pf	126	65	,	,	,
cord-256444-grw5s2pf	126	66	suggesting	suggest	VBG
cord-256444-grw5s2pf	126	67	that	that	IN
cord-256444-grw5s2pf	126	68	this	this	DT
cord-256444-grw5s2pf	126	69	region	region	NN
cord-256444-grw5s2pf	126	70	is	be	VBZ
cord-256444-grw5s2pf	126	71	externally	externally	RB
cord-256444-grw5s2pf	126	72	exposed	expose	VBN
cord-256444-grw5s2pf	126	73	and	and	CC
cord-256444-grw5s2pf	126	74	not	not	RB
cord-256444-grw5s2pf	126	75	essential	essential	JJ
cord-256444-grw5s2pf	126	76	for	for	IN
cord-256444-grw5s2pf	126	77	the	the	DT
cord-256444-grw5s2pf	126	78	structure	structure	NN
cord-256444-grw5s2pf	126	79	.	.	.
cord-256444-grw5s2pf	127	1	The	the	DT
cord-256444-grw5s2pf	127	2	S2	s2	NN
cord-256444-grw5s2pf	127	3	polypeptide	polypeptide	NN
cord-256444-grw5s2pf	127	4	has	have	VBZ
cord-256444-grw5s2pf	127	5	two	two	CD
cord-256444-grw5s2pf	127	6	regions	region	NNS
cord-256444-grw5s2pf	127	7	with	with	IN
cord-256444-grw5s2pf	127	8	a	a	DT
cord-256444-grw5s2pf	127	9	seven	seven	CD
cord-256444-grw5s2pf	127	10	-	-	HYPH
cord-256444-grw5s2pf	127	11	residue	residue	NN
cord-256444-grw5s2pf	127	12	periodicity	periodicity	NN
cord-256444-grw5s2pf	127	13	,	,	,
cord-256444-grw5s2pf	127	14	forming	form	VBG
cord-256444-grw5s2pf	127	15	heptad	heptad	NN
cord-256444-grw5s2pf	127	16	repeats	repeat	NNS
cord-256444-grw5s2pf	127	17	(	(	-LRB-
cord-256444-grw5s2pf	127	18	Fig	Fig	NNP
cord-256444-grw5s2pf	127	19	.	.	.
cord-256444-grw5s2pf	127	20	4	4	LS
cord-256444-grw5s2pf	127	21	)	)	-RRB-
cord-256444-grw5s2pf	127	22	indicative	indicative	JJ
cord-256444-grw5s2pf	127	23	of	of	IN
cord-256444-grw5s2pf	127	24	a	a	DT
cord-256444-grw5s2pf	127	25	coiled	coil	VBN
cord-256444-grw5s2pf	127	26	-	-	HYPH
cord-256444-grw5s2pf	127	27	coil	coil	NN
cord-256444-grw5s2pf	127	28	structure	structure	NN
cord-256444-grw5s2pf	127	29	(	(	-LRB-
cord-256444-grw5s2pf	127	30	de	de	FW
cord-256444-grw5s2pf	127	31	Groot	Groot	NNP
cord-256444-grw5s2pf	127	32	et	et	FW
cord-256444-grw5s2pf	127	33	al	al	NNP
cord-256444-grw5s2pf	127	34	.	.	NNP
cord-256444-grw5s2pf	127	35	,	,	,
cord-256444-grw5s2pf	127	36	1987	1987	CD
cord-256444-grw5s2pf	127	37	)	)	-RRB-
cord-256444-grw5s2pf	127	38	.	.	.
cord-256444-grw5s2pf	128	1	Indeed	indeed	RB
cord-256444-grw5s2pf	128	2	,	,	,
cord-256444-grw5s2pf	128	3	current	current	JJ
cord-256444-grw5s2pf	128	4	evidence	evidence	NN
cord-256444-grw5s2pf	128	5	suggests	suggest	VBZ
cord-256444-grw5s2pf	128	6	that	that	IN
cord-256444-grw5s2pf	128	7	the	the	DT
cord-256444-grw5s2pf	128	8	mature	mature	NNP
cord-256444-grw5s2pf	128	9	S	S	NNP
cord-256444-grw5s2pf	128	10	protein	protein	NN
cord-256444-grw5s2pf	128	11	forms	form	VBZ
cord-256444-grw5s2pf	128	12	an	an	DT
cord-256444-grw5s2pf	128	13	oligomer	oligomer	NN
cord-256444-grw5s2pf	128	14	;	;	:
cord-256444-grw5s2pf	128	15	for	for	IN
cord-256444-grw5s2pf	128	16	TGEV	TGEV	NNP
cord-256444-grw5s2pf	128	17	,	,	,
cord-256444-grw5s2pf	128	18	it	-PRON-	PRP
cord-256444-grw5s2pf	128	19	is	be	VBZ
cord-256444-grw5s2pf	128	20	probably	probably	RB
cord-256444-grw5s2pf	128	21	a	a	DT
cord-256444-grw5s2pf	128	22	trimer	trimer	NN
cord-256444-grw5s2pf	128	23	(	(	-LRB-
cord-256444-grw5s2pf	128	24	Delmas	Delmas	NNP
cord-256444-grw5s2pf	128	25	and	and	CC
cord-256444-grw5s2pf	128	26	Laude	Laude	NNP
cord-256444-grw5s2pf	128	27	,	,	,
cord-256444-grw5s2pf	128	28	1990	1990	CD
cord-256444-grw5s2pf	128	29	)	)	-RRB-
cord-256444-grw5s2pf	128	30	.	.	.
cord-256444-grw5s2pf	129	1	However	however	RB
cord-256444-grw5s2pf	129	2	,	,	,
cord-256444-grw5s2pf	129	3	a	a	DT
cord-256444-grw5s2pf	129	4	dimer	dimer	NN
cord-256444-grw5s2pf	129	5	structure	structure	NN
cord-256444-grw5s2pf	129	6	has	have	VBZ
cord-256444-grw5s2pf	129	7	been	be	VBN
cord-256444-grw5s2pf	129	8	proposed	propose	VBN
cord-256444-grw5s2pf	129	9	for	for	IN
cord-256444-grw5s2pf	129	10	IBV	IBV	NNP
cord-256444-grw5s2pf	129	11	S	S	NNP
cord-256444-grw5s2pf	129	12	protein	protein	NN
cord-256444-grw5s2pf	129	13	(	(	-LRB-
cord-256444-grw5s2pf	129	14	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	129	15	,	,	,
cord-256444-grw5s2pf	129	16	1983~	1983~	CD
cord-256444-grw5s2pf	129	17	)	)	-RRB-
cord-256444-grw5s2pf	129	18	.	.	.
cord-256444-grw5s2pf	130	1	Therefore	therefore	RB
cord-256444-grw5s2pf	130	2	,	,	,
cord-256444-grw5s2pf	130	3	the	the	DT
cord-256444-grw5s2pf	130	4	oligomeric	oligomeric	NN
cord-256444-grw5s2pf	130	5	S	S	NNP
cord-256444-grw5s2pf	130	6	protein	protein	NN
cord-256444-grw5s2pf	130	7	is	be	VBZ
cord-256444-grw5s2pf	130	8	envisaged	envisage	VBN
cord-256444-grw5s2pf	130	9	as	as	IN
cord-256444-grw5s2pf	130	10	being	be	VBG
cord-256444-grw5s2pf	130	11	anchored	anchor	VBN
cord-256444-grw5s2pf	130	12	in	in	IN
cord-256444-grw5s2pf	130	13	the	the	DT
cord-256444-grw5s2pf	130	14	membrane	membrane	NN
cord-256444-grw5s2pf	130	15	by	by	IN
cord-256444-grw5s2pf	130	16	a	a	DT
cord-256444-grw5s2pf	130	17	n	n	NN
cord-256444-grw5s2pf	130	18	a	a	DT
cord-256444-grw5s2pf	130	19	-	-	HYPH
cord-256444-grw5s2pf	130	20	helical	helical	JJ
cord-256444-grw5s2pf	130	21	region	region	NN
cord-256444-grw5s2pf	130	22	near	near	IN
cord-256444-grw5s2pf	130	23	to	to	IN
cord-256444-grw5s2pf	130	24	the	the	DT
cord-256444-grw5s2pf	130	25	C	C	NNP
cord-256444-grw5s2pf	130	26	terminus	terminus	NN
cord-256444-grw5s2pf	130	27	of	of	IN
cord-256444-grw5s2pf	130	28	S2	S2	NNP
cord-256444-grw5s2pf	130	29	.	.	.
cord-256444-grw5s2pf	131	1	Just	just	RB
cord-256444-grw5s2pf	131	2	beyond	beyond	IN
cord-256444-grw5s2pf	131	3	the	the	DT
cord-256444-grw5s2pf	131	4	outer	outer	JJ
cord-256444-grw5s2pf	131	5	membrane	membrane	NN
cord-256444-grw5s2pf	131	6	surface	surface	NN
cord-256444-grw5s2pf	131	7	is	be	VBZ
cord-256444-grw5s2pf	131	8	the	the	DT
cord-256444-grw5s2pf	131	9	shorter	short	JJR
cord-256444-grw5s2pf	131	10	(	(	-LRB-
cord-256444-grw5s2pf	131	11	minor	minor	JJ
cord-256444-grw5s2pf	131	12	)	)	-RRB-
cord-256444-grw5s2pf	131	13	repeat	repeat	NN
cord-256444-grw5s2pf	131	14	structure	structure	NN
cord-256444-grw5s2pf	131	15	predicted	predict	VBD
cord-256444-grw5s2pf	131	16	to	to	TO
cord-256444-grw5s2pf	131	17	be	be	VB
cord-256444-grw5s2pf	131	18	an	an	DT
cord-256444-grw5s2pf	131	19	a	a	NN
cord-256444-grw5s2pf	131	20	!	!	.
cord-256444-grw5s2pf	132	1	helix	helix	NNP
cord-256444-grw5s2pf	132	2	of	of	IN
cord-256444-grw5s2pf	132	3	5	5	CD
cord-256444-grw5s2pf	132	4	-	-	SYM
cord-256444-grw5s2pf	132	5	7	7	CD
cord-256444-grw5s2pf	132	6	nm	nm	NN
cord-256444-grw5s2pf	132	7	.	.	.
cord-256444-grw5s2pf	133	1	The	the	DT
cord-256444-grw5s2pf	133	2	major	major	JJ
cord-256444-grw5s2pf	133	3	repeat	repeat	NN
cord-256444-grw5s2pf	133	4	indicates	indicate	VBZ
cord-256444-grw5s2pf	133	5	a	a	DT
cord-256444-grw5s2pf	133	6	helix	helix	NN
cord-256444-grw5s2pf	133	7	of	of	IN
cord-256444-grw5s2pf	133	8	10	10	CD
cord-256444-grw5s2pf	133	9	-	-	SYM
cord-256444-grw5s2pf	133	10	13	13	CD
cord-256444-grw5s2pf	133	11	nm	nm	NN
cord-256444-grw5s2pf	133	12	,	,	,
cord-256444-grw5s2pf	133	13	which	which	WDT
cord-256444-grw5s2pf	133	14	may	may	MD
cord-256444-grw5s2pf	133	15	form	form	VB
cord-256444-grw5s2pf	133	16	the	the	DT
cord-256444-grw5s2pf	133	17	narrow	narrow	JJ
cord-256444-grw5s2pf	133	18	stalk	stalk	NN
cord-256444-grw5s2pf	133	19	of	of	IN
cord-256444-grw5s2pf	133	20	the	the	DT
cord-256444-grw5s2pf	133	21	spikes	spike	NNS
cord-256444-grw5s2pf	133	22	(	(	-LRB-
cord-256444-grw5s2pf	133	23	de	de	FW
cord-256444-grw5s2pf	133	24	Groot	Groot	NNP
cord-256444-grw5s2pf	133	25	et	et	FW
cord-256444-grw5s2pf	133	26	al	al	NNP
cord-256444-grw5s2pf	133	27	.	.	NNP
cord-256444-grw5s2pf	133	28	,	,	,
cord-256444-grw5s2pf	133	29	1987	1987	CD
cord-256444-grw5s2pf	133	30	)	)	-RRB-
cord-256444-grw5s2pf	133	31	.	.	.
cord-256444-grw5s2pf	134	1	All	all	DT
cord-256444-grw5s2pf	134	2	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	134	3	S2	s2	NN
cord-256444-grw5s2pf	134	4	proteins	protein	NNS
cord-256444-grw5s2pf	134	5	have	have	VBP
cord-256444-grw5s2pf	134	6	a	a	DT
cord-256444-grw5s2pf	134	7	highly	highly	RB
cord-256444-grw5s2pf	134	8	conserved	conserve	VBN
cord-256444-grw5s2pf	134	9	eight	eight	CD
cord-256444-grw5s2pf	134	10	-	-	HYPH
cord-256444-grw5s2pf	134	11	residue	residue	NN
cord-256444-grw5s2pf	134	12	sequence	sequence	NN
cord-256444-grw5s2pf	134	13	KWPWW	KWPWW	NNP
cord-256444-grw5s2pf	134	14	/	/	SYM
cord-256444-grw5s2pf	134	15	YVWL	YVWL	NNP
cord-256444-grw5s2pf	134	16	,	,	,
cord-256444-grw5s2pf	134	17	the	the	DT
cord-256444-grw5s2pf	134	18	last	last	JJ
cord-256444-grw5s2pf	134	19	five	five	CD
cord-256444-grw5s2pf	134	20	residues	residue	NNS
cord-256444-grw5s2pf	134	21	of	of	IN
cord-256444-grw5s2pf	134	22	which	which	WDT
cord-256444-grw5s2pf	134	23	probably	probably	RB
cord-256444-grw5s2pf	134	24	form	form	VBP
cord-256444-grw5s2pf	134	25	the	the	DT
cord-256444-grw5s2pf	134	26	beginning	beginning	NN
cord-256444-grw5s2pf	134	27	of	of	IN
cord-256444-grw5s2pf	134	28	the	the	DT
cord-256444-grw5s2pf	134	29	membrane	membrane	NN
cord-256444-grw5s2pf	134	30	-	-	HYPH
cord-256444-grw5s2pf	134	31	spanning	span	VBG
cord-256444-grw5s2pf	134	32	domain	domain	NN
cord-256444-grw5s2pf	134	33	.	.	.
cord-256444-grw5s2pf	135	1	Terminating	terminate	VBG
cord-256444-grw5s2pf	135	2	10	10	CD
cord-256444-grw5s2pf	135	3	residues	residue	NNS
cord-256444-grw5s2pf	135	4	upstream	upstream	RB
cord-256444-grw5s2pf	135	5	of	of	IN
cord-256444-grw5s2pf	135	6	KWP	KWP	NNP
cord-256444-grw5s2pf	135	7	is	be	VBZ
cord-256444-grw5s2pf	135	8	a	a	DT
cord-256444-grw5s2pf	135	9	leucine	leucine	NN
cord-256444-grw5s2pf	135	10	-	-	HYPH
cord-256444-grw5s2pf	135	11	zipper	zipper	NN
cord-256444-grw5s2pf	135	12	motif	motif	NN
cord-256444-grw5s2pf	135	13	,	,	,
cord-256444-grw5s2pf	135	14	the	the	DT
cord-256444-grw5s2pf	135	15	length	length	NN
cord-256444-grw5s2pf	135	16	varying	vary	VBG
cord-256444-grw5s2pf	135	17	from	from	IN
cord-256444-grw5s2pf	135	18	three	three	CD
cord-256444-grw5s2pf	135	19	to	to	TO
cord-256444-grw5s2pf	135	20	five	five	CD
cord-256444-grw5s2pf	135	21	heptad	heptad	NN
cord-256444-grw5s2pf	135	22	repeats	repeat	VBZ
cord-256444-grw5s2pf	135	23	(	(	-LRB-
cord-256444-grw5s2pf	135	24	Britton	Britton	NNP
cord-256444-grw5s2pf	135	25	,	,	,
cord-256444-grw5s2pf	135	26	1991	1991	CD
cord-256444-grw5s2pf	135	27	)	)	-RRB-
cord-256444-grw5s2pf	135	28	.	.	.
cord-256444-grw5s2pf	136	1	The	the	DT
cord-256444-grw5s2pf	136	2	highly	highly	RB
cord-256444-grw5s2pf	136	3	conserved	conserved	JJ
cord-256444-grw5s2pf	136	4	sequences	sequence	NNS
cord-256444-grw5s2pf	136	5	of	of	IN
cord-256444-grw5s2pf	136	6	S2	S2	NNP
cord-256444-grw5s2pf	136	7	may	may	MD
cord-256444-grw5s2pf	136	8	play	play	VB
cord-256444-grw5s2pf	136	9	a	a	DT
cord-256444-grw5s2pf	136	10	role	role	NN
cord-256444-grw5s2pf	136	11	in	in	IN
cord-256444-grw5s2pf	136	12	forming	form	VBG
cord-256444-grw5s2pf	136	13	the	the	DT
cord-256444-grw5s2pf	136	14	stalk	stalk	NN
cord-256444-grw5s2pf	136	15	,	,	,
cord-256444-grw5s2pf	136	16	which	which	WDT
cord-256444-grw5s2pf	136	17	has	have	VBZ
cord-256444-grw5s2pf	136	18	a	a	DT
cord-256444-grw5s2pf	136	19	more	more	RBR
cord-256444-grw5s2pf	136	20	rigid	rigid	JJ
cord-256444-grw5s2pf	136	21	structure	structure	NN
cord-256444-grw5s2pf	136	22	.	.	.
cord-256444-grw5s2pf	137	1	In	in	IN
cord-256444-grw5s2pf	137	2	contrast	contrast	NN
cord-256444-grw5s2pf	137	3	,	,	,
cord-256444-grw5s2pf	137	4	the	the	DT
cord-256444-grw5s2pf	137	5	S1	s1	NN
cord-256444-grw5s2pf	137	6	domain	domain	NN
cord-256444-grw5s2pf	137	7	is	be	VBZ
cord-256444-grw5s2pf	137	8	predicted	predict	VBN
cord-256444-grw5s2pf	137	9	to	to	TO
cord-256444-grw5s2pf	137	10	form	form	VB
cord-256444-grw5s2pf	137	11	the	the	DT
cord-256444-grw5s2pf	137	12	globular	globular	JJ
cord-256444-grw5s2pf	137	13	portion	portion	NN
cord-256444-grw5s2pf	137	14	of	of	IN
cord-256444-grw5s2pf	137	15	the	the	DT
cord-256444-grw5s2pf	137	16	spikes	spike	NNS
cord-256444-grw5s2pf	137	17	,	,	,
cord-256444-grw5s2pf	137	18	consistent	consistent	JJ
cord-256444-grw5s2pf	137	19	with	with	IN
cord-256444-grw5s2pf	137	20	its	-PRON-	PRP$
cord-256444-grw5s2pf	137	21	highly	highly	RB
cord-256444-grw5s2pf	137	22	variable	variable	JJ
cord-256444-grw5s2pf	137	23	nature	nature	NN
cord-256444-grw5s2pf	137	24	.	.	.
cord-256444-grw5s2pf	138	1	The	the	DT
cord-256444-grw5s2pf	138	2	S	S	NNP
cord-256444-grw5s2pf	138	3	protein	protein	NN
cord-256444-grw5s2pf	138	4	has	have	VBZ
cord-256444-grw5s2pf	138	5	two	two	CD
cord-256444-grw5s2pf	138	6	important	important	JJ
cord-256444-grw5s2pf	138	7	biological	biological	JJ
cord-256444-grw5s2pf	138	8	activities	activity	NNS
cord-256444-grw5s2pf	138	9	for	for	IN
cord-256444-grw5s2pf	138	10	the	the	DT
cord-256444-grw5s2pf	138	11	virus	virus	NN
cord-256444-grw5s2pf	138	12	:	:	:
cord-256444-grw5s2pf	138	13	a.	a.	NN
cord-256444-grw5s2pf	138	14	Induction	Induction	NNP
cord-256444-grw5s2pf	138	15	of	of	IN
cord-256444-grw5s2pf	138	16	Membrane	Membrane	NNP
cord-256444-grw5s2pf	138	17	Fusion	Fusion	NNP
cord-256444-grw5s2pf	138	18	.	.	.
cord-256444-grw5s2pf	139	1	This	this	DT
cord-256444-grw5s2pf	139	2	activity	activity	NN
cord-256444-grw5s2pf	139	3	may	may	MD
cord-256444-grw5s2pf	139	4	be	be	VB
cord-256444-grw5s2pf	139	5	required	require	VBN
cord-256444-grw5s2pf	139	6	for	for	IN
cord-256444-grw5s2pf	139	7	viral	viral	JJ
cord-256444-grw5s2pf	139	8	entry	entry	NN
cord-256444-grw5s2pf	139	9	into	into	IN
cord-256444-grw5s2pf	139	10	cells	cell	NNS
cord-256444-grw5s2pf	139	11	or	or	CC
cord-256444-grw5s2pf	139	12	for	for	IN
cord-256444-grw5s2pf	139	13	cytopathic	cytopathic	JJ
cord-256444-grw5s2pf	139	14	effects	effect	NNS
cord-256444-grw5s2pf	139	15	.	.	.
cord-256444-grw5s2pf	140	1	Expression	expression	NN
cord-256444-grw5s2pf	140	2	of	of	IN
cord-256444-grw5s2pf	140	3	the	the	DT
cord-256444-grw5s2pf	140	4	recombinant	recombinant	JJ
cord-256444-grw5s2pf	140	5	S	S	NNP
cord-256444-grw5s2pf	140	6	gene	gene	NN
cord-256444-grw5s2pf	140	7	has	have	VBZ
cord-256444-grw5s2pf	140	8	provided	provide	VBN
cord-256444-grw5s2pf	140	9	unequivocal	unequivocal	JJ
cord-256444-grw5s2pf	140	10	evidence	evidence	NN
cord-256444-grw5s2pf	140	11	that	that	IN
cord-256444-grw5s2pf	140	12	the	the	DT
cord-256444-grw5s2pf	140	13	S	S	NNP
cord-256444-grw5s2pf	140	14	protein	protein	NN
cord-256444-grw5s2pf	140	15	alone	alone	RB
cord-256444-grw5s2pf	140	16	is	be	VBZ
cord-256444-grw5s2pf	140	17	sufficient	sufficient	JJ
cord-256444-grw5s2pf	140	18	to	to	TO
cord-256444-grw5s2pf	140	19	cause	cause	VB
cord-256444-grw5s2pf	140	20	membrane	membrane	NN
cord-256444-grw5s2pf	140	21	fusion	fusion	NN
cord-256444-grw5s2pf	140	22	,	,	,
cord-256444-grw5s2pf	140	23	as	as	IN
cord-256444-grw5s2pf	140	24	shown	show	VBN
cord-256444-grw5s2pf	140	25	by	by	IN
cord-256444-grw5s2pf	140	26	syncytium	syncytium	NN
cord-256444-grw5s2pf	140	27	formation	formation	NN
cord-256444-grw5s2pf	141	1	(	(	-LRB-
cord-256444-grw5s2pf	141	2	de	de	FW
cord-256444-grw5s2pf	141	3	Groot	Groot	NNP
cord-256444-grw5s2pf	141	4	et	et	FW
cord-256444-grw5s2pf	141	5	al	al	NNP
cord-256444-grw5s2pf	141	6	.	.	.
cord-256444-grw5s2pf	142	1	,	,	,
cord-256444-grw5s2pf	142	2	1989	1989	CD
cord-256444-grw5s2pf	142	3	;	;	:
cord-256444-grw5s2pf	142	4	Pfleiderer	Pfleiderer	NNP
cord-256444-grw5s2pf	142	5	et	et	NNP
cord-256444-grw5s2pf	142	6	al	al	NNP
cord-256444-grw5s2pf	142	7	.	.	NNP
cord-256444-grw5s2pf	142	8	,	,	,
cord-256444-grw5s2pf	142	9	1990	1990	CD
cord-256444-grw5s2pf	142	10	;	;	:
cord-256444-grw5s2pf	142	11	Yo0	Yo0	NNP
cord-256444-grw5s2pf	142	12	et	et	NNP
cord-256444-grw5s2pf	142	13	al	al	NNP
cord-256444-grw5s2pf	142	14	.	.	NNP
cord-256444-grw5s2pf	142	15	,	,	,
cord-256444-grw5s2pf	142	16	1991	1991	CD
cord-256444-grw5s2pf	143	1	;	;	:
cord-256444-grw5s2pf	143	2	Taguchi	Taguchi	NNP
cord-256444-grw5s2pf	143	3	,	,	,
cord-256444-grw5s2pf	143	4	1993	1993	CD
cord-256444-grw5s2pf	143	5	)	)	-RRB-
cord-256444-grw5s2pf	143	6	.	.	.
cord-256444-grw5s2pf	144	1	Several	several	JJ
cord-256444-grw5s2pf	144	2	regions	region	NNS
cord-256444-grw5s2pf	144	3	of	of	IN
cord-256444-grw5s2pf	144	4	the	the	DT
cord-256444-grw5s2pf	144	5	S	S	NNP
cord-256444-grw5s2pf	144	6	protein	protein	NN
cord-256444-grw5s2pf	144	7	,	,	,
cord-256444-grw5s2pf	144	8	widely	widely	RB
cord-256444-grw5s2pf	144	9	separated	separate	VBN
cord-256444-grw5s2pf	144	10	in	in	IN
cord-256444-grw5s2pf	144	11	a	a	DT
cord-256444-grw5s2pf	144	12	linear	linear	JJ
cord-256444-grw5s2pf	144	13	sense	sense	NN
cord-256444-grw5s2pf	144	14	,	,	,
cord-256444-grw5s2pf	144	15	have	have	VBP
cord-256444-grw5s2pf	144	16	been	be	VBN
cord-256444-grw5s2pf	144	17	implicated	implicate	VBN
cord-256444-grw5s2pf	144	18	in	in	IN
cord-256444-grw5s2pf	144	19	the	the	DT
cord-256444-grw5s2pf	144	20	membrane	membrane	NN
cord-256444-grw5s2pf	144	21	fusion	fusion	NN
cord-256444-grw5s2pf	144	22	process	process	NN
cord-256444-grw5s2pf	144	23	by	by	IN
cord-256444-grw5s2pf	144	24	the	the	DT
cord-256444-grw5s2pf	144	25	following	follow	VBG
cord-256444-grw5s2pf	144	26	observations	observation	NNS
cord-256444-grw5s2pf	144	27	:	:	:
cord-256444-grw5s2pf	144	28	(	(	-LRB-
cord-256444-grw5s2pf	144	29	1	1	LS
cord-256444-grw5s2pf	144	30	)	)	-RRB-
cord-256444-grw5s2pf	144	31	S2	s2	NN
cord-256444-grw5s2pf	144	32	of	of	IN
cord-256444-grw5s2pf	144	33	BCV	BCV	NNP
cord-256444-grw5s2pf	144	34	expressed	express	VBD
cord-256444-grw5s2pf	144	35	in	in	IN
cord-256444-grw5s2pf	144	36	insect	insect	NN
cord-256444-grw5s2pf	144	37	cells	cell	NNS
cord-256444-grw5s2pf	144	38	caused	cause	VBD
cord-256444-grw5s2pf	144	39	fusion	fusion	NN
cord-256444-grw5s2pf	144	40	(	(	-LRB-
cord-256444-grw5s2pf	144	41	Yo0	Yo0	NNP
cord-256444-grw5s2pf	144	42	et	et	FW
cord-256444-grw5s2pf	144	43	al	al	NNP
cord-256444-grw5s2pf	144	44	.	.	NNP
cord-256444-grw5s2pf	144	45	,	,	,
cord-256444-grw5s2pf	144	46	1991	1991	CD
cord-256444-grw5s2pf	144	47	)	)	-RRB-
cord-256444-grw5s2pf	144	48	.	.	.
cord-256444-grw5s2pf	145	1	(	(	-LRB-
cord-256444-grw5s2pf	145	2	2	2	LS
cord-256444-grw5s2pf	145	3	)	)	-RRB-
cord-256444-grw5s2pf	145	4	A	a	DT
cord-256444-grw5s2pf	145	5	monoclonal	monoclonal	JJ
cord-256444-grw5s2pf	145	6	antibody	antibody	NN
cord-256444-grw5s2pf	145	7	that	that	WDT
cord-256444-grw5s2pf	145	8	inhibited	inhibited	JJ
cord-256444-grw5s2pf	145	9	cell	cell	NN
cord-256444-grw5s2pf	145	10	fusion	fusion	NN
cord-256444-grw5s2pf	145	11	was	be	VBD
cord-256444-grw5s2pf	145	12	shown	show	VBN
cord-256444-grw5s2pf	145	13	to	to	TO
cord-256444-grw5s2pf	145	14	bind	bind	VB
cord-256444-grw5s2pf	145	15	to	to	IN
cord-256444-grw5s2pf	145	16	the	the	DT
cord-256444-grw5s2pf	145	17	S2	S2	NNP
cord-256444-grw5s2pf	145	18	domain	domain	NN
cord-256444-grw5s2pf	145	19	of	of	IN
cord-256444-grw5s2pf	145	20	MHV	MHV	NNP
cord-256444-grw5s2pf	145	21	(	(	-LRB-
cord-256444-grw5s2pf	145	22	Fig	Fig	NNP
cord-256444-grw5s2pf	145	23	.	.	.
cord-256444-grw5s2pf	145	24	4	4	CD
cord-256444-grw5s2pf	145	25	)	)	-RRB-
cord-256444-grw5s2pf	146	1	(	(	-LRB-
cord-256444-grw5s2pf	146	2	Luytjes	Luytjes	NNP
cord-256444-grw5s2pf	146	3	et	et	NNP
cord-256444-grw5s2pf	146	4	al	al	NNP
cord-256444-grw5s2pf	146	5	.	.	NNP
cord-256444-grw5s2pf	146	6	,	,	,
cord-256444-grw5s2pf	146	7	1989	1989	CD
cord-256444-grw5s2pf	146	8	)	)	-RRB-
cord-256444-grw5s2pf	146	9	.	.	.
cord-256444-grw5s2pf	147	1	(	(	-LRB-
cord-256444-grw5s2pf	147	2	3	3	LS
cord-256444-grw5s2pf	147	3	)	)	-RRB-
cord-256444-grw5s2pf	147	4	Changes	change	NNS
cord-256444-grw5s2pf	147	5	at	at	IN
cord-256444-grw5s2pf	147	6	three	three	CD
cord-256444-grw5s2pf	147	7	S2	s2	NN
cord-256444-grw5s2pf	147	8	residues	residue	NNS
cord-256444-grw5s2pf	147	9	(	(	-LRB-
cord-256444-grw5s2pf	147	10	1067	1067	CD
cord-256444-grw5s2pf	147	11	,	,	,
cord-256444-grw5s2pf	147	12	1094	1094	CD
cord-256444-grw5s2pf	147	13	,	,	,
cord-256444-grw5s2pf	147	14	and	and	CC
cord-256444-grw5s2pf	147	15	1114	1114	CD
cord-256444-grw5s2pf	147	16	in	in	IN
cord-256444-grw5s2pf	147	17	the	the	DT
cord-256444-grw5s2pf	147	18	MHV4	MHV4	NNP
cord-256444-grw5s2pf	147	19	S	S	NNP
cord-256444-grw5s2pf	147	20	protein	protein	NN
cord-256444-grw5s2pf	147	21	;	;	:
cord-256444-grw5s2pf	147	22	Fig	Fig	NNP
cord-256444-grw5s2pf	147	23	.	.	NNP
cord-256444-grw5s2pf	147	24	4	4	LS
cord-256444-grw5s2pf	147	25	)	)	-RRB-
cord-256444-grw5s2pf	147	26	were	be	VBD
cord-256444-grw5s2pf	147	27	associated	associate	VBN
cord-256444-grw5s2pf	147	28	with	with	IN
cord-256444-grw5s2pf	147	29	a	a	DT
cord-256444-grw5s2pf	147	30	change	change	NN
cord-256444-grw5s2pf	147	31	from	from	IN
cord-256444-grw5s2pf	147	32	a	a	DT
cord-256444-grw5s2pf	147	33	requirement	requirement	NN
cord-256444-grw5s2pf	147	34	for	for	IN
cord-256444-grw5s2pf	147	35	a	a	DT
cord-256444-grw5s2pf	147	36	neutral	neutral	JJ
cord-256444-grw5s2pf	147	37	pH	ph	NN
cord-256444-grw5s2pf	147	38	to	to	IN
cord-256444-grw5s2pf	147	39	an	an	DT
cord-256444-grw5s2pf	147	40	acidic	acidic	JJ
cord-256444-grw5s2pf	147	41	pH	ph	NN
cord-256444-grw5s2pf	147	42	for	for	IN
cord-256444-grw5s2pf	147	43	fusion	fusion	NN
cord-256444-grw5s2pf	147	44	(	(	-LRB-
cord-256444-grw5s2pf	147	45	Gallagher	Gallagher	NNP
cord-256444-grw5s2pf	147	46	et	et	NNP
cord-256444-grw5s2pf	147	47	al	al	NNP
cord-256444-grw5s2pf	147	48	.	.	NNP
cord-256444-grw5s2pf	147	49	,	,	,
cord-256444-grw5s2pf	147	50	1991	1991	CD
cord-256444-grw5s2pf	147	51	)	)	-RRB-
cord-256444-grw5s2pf	147	52	.	.	.
cord-256444-grw5s2pf	148	1	(	(	-LRB-
cord-256444-grw5s2pf	148	2	4	4	LS
cord-256444-grw5s2pf	148	3	)	)	-RRB-
cord-256444-grw5s2pf	149	1	Two	two	CD
cord-256444-grw5s2pf	149	2	bacterial	bacterial	JJ
cord-256444-grw5s2pf	149	3	expression	expression	NN
cord-256444-grw5s2pf	149	4	products	product	NNS
cord-256444-grw5s2pf	149	5	containing	contain	VBG
cord-256444-grw5s2pf	149	6	residues	residue	NNS
cord-256444-grw5s2pf	149	7	33	33	CD
cord-256444-grw5s2pf	149	8	-	-	HYPH
cord-256444-grw5s2pf	149	9	4061	4061	CD
cord-256444-grw5s2pf	149	10	)	)	-RRB-
cord-256444-grw5s2pf	149	11	and	and	CC
cord-256444-grw5s2pf	149	12	1264	1264	CD
cord-256444-grw5s2pf	149	13	-	-	HYPH
cord-256444-grw5s2pf	149	14	1276	1276	CD
cord-256444-grw5s2pf	149	15	6	6	CD
cord-256444-grw5s2pf	149	16	2	2	CD
cord-256444-grw5s2pf	149	17	)	)	-RRB-
cord-256444-grw5s2pf	150	1	ofthe	ofthe	DT
cord-256444-grw5s2pf	150	2	JHM	JHM	NNP
cord-256444-grw5s2pf	150	3	strain	strain	VB
cord-256444-grw5s2pf	150	4	ofMHVinducedmonoclonal	ofmhvinducedmonoclonal	JJ
cord-256444-grw5s2pf	150	5	antibodies	antibody	NNS
cord-256444-grw5s2pf	150	6	11F	11f	CD
cord-256444-grw5s2pf	150	7	and	and	CC
cord-256444-grw5s2pf	150	8	10	10	CD
cord-256444-grw5s2pf	150	9	G	g	NN
cord-256444-grw5s2pf	150	10	,	,	,
cord-256444-grw5s2pf	150	11	respectively	respectively	RB
cord-256444-grw5s2pf	150	12	,	,	,
cord-256444-grw5s2pf	150	13	both	both	DT
cord-256444-grw5s2pf	150	14	of	of	IN
cord-256444-grw5s2pf	150	15	which	which	WDT
cord-256444-grw5s2pf	150	16	inhibited	inhibited	JJ
cord-256444-grw5s2pf	150	17	fusion	fusion	NN
cord-256444-grw5s2pf	150	18	(	(	-LRB-
cord-256444-grw5s2pf	150	19	Fig	Fig	NNP
cord-256444-grw5s2pf	150	20	.	.	NNP
cord-256444-grw5s2pf	150	21	4	4	CD
cord-256444-grw5s2pf	150	22	)	)	-RRB-
cord-256444-grw5s2pf	150	23	.	.	.
cord-256444-grw5s2pf	151	1	(	(	-LRB-
cord-256444-grw5s2pf	151	2	5	5	LS
cord-256444-grw5s2pf	151	3	)	)	-RRB-
cord-256444-grw5s2pf	152	1	Chemical	chemical	JJ
cord-256444-grw5s2pf	152	2	modifications	modification	NNS
cord-256444-grw5s2pf	152	3	of	of	IN
cord-256444-grw5s2pf	152	4	the	the	DT
cord-256444-grw5s2pf	152	5	cysteine	cysteine	NN
cord-256444-grw5s2pf	152	6	residues	residue	NNS
cord-256444-grw5s2pf	152	7	,	,	,
cord-256444-grw5s2pf	152	8	specifically	specifically	RB
cord-256444-grw5s2pf	152	9	residue	residue	JJ
cord-256444-grw5s2pf	152	10	1163	1163	CD
cord-256444-grw5s2pf	152	11	in	in	IN
cord-256444-grw5s2pf	152	12	the	the	DT
cord-256444-grw5s2pf	152	13	ectodomain	ectodomain	NN
cord-256444-grw5s2pf	152	14	of	of	IN
cord-256444-grw5s2pf	152	15	S2	S2	NNP
cord-256444-grw5s2pf	152	16	,	,	,
cord-256444-grw5s2pf	152	17	reduced	reduce	VBD
cord-256444-grw5s2pf	152	18	the	the	DT
cord-256444-grw5s2pf	152	19	fusion	fusion	NN
cord-256444-grw5s2pf	152	20	activity	activity	NN
cord-256444-grw5s2pf	152	21	of	of	IN
cord-256444-grw5s2pf	152	22	the	the	DT
cord-256444-grw5s2pf	152	23	JHM	JHM	NNP
cord-256444-grw5s2pf	152	24	strain	strain	NN
cord-256444-grw5s2pf	152	25	of	of	IN
cord-256444-grw5s2pf	152	26	MHV	MHV	NNP
cord-256444-grw5s2pf	152	27	(	(	-LRB-
cord-256444-grw5s2pf	152	28	Gallagher	Gallagher	NNP
cord-256444-grw5s2pf	152	29	,	,	,
cord-256444-grw5s2pf	152	30	1996	1996	CD
cord-256444-grw5s2pf	152	31	)	)	-RRB-
cord-256444-grw5s2pf	152	32	.	.	.
cord-256444-grw5s2pf	153	1	This	this	DT
cord-256444-grw5s2pf	153	2	result	result	NN
cord-256444-grw5s2pf	153	3	also	also	RB
cord-256444-grw5s2pf	153	4	suggests	suggest	VBZ
cord-256444-grw5s2pf	153	5	strain	strain	NN
cord-256444-grw5s2pf	153	6	-	-	HYPH
cord-256444-grw5s2pf	153	7	specific	specific	JJ
cord-256444-grw5s2pf	153	8	differences	difference	NNS
cord-256444-grw5s2pf	153	9	in	in	IN
cord-256444-grw5s2pf	153	10	the	the	DT
cord-256444-grw5s2pf	153	11	conformation	conformation	NN
cord-256444-grw5s2pf	153	12	of	of	IN
cord-256444-grw5s2pf	153	13	the	the	DT
cord-256444-grw5s2pf	153	14	S	S	NNP
cord-256444-grw5s2pf	153	15	protein	protein	NN
cord-256444-grw5s2pf	153	16	,	,	,
cord-256444-grw5s2pf	153	17	since	since	IN
cord-256444-grw5s2pf	153	18	the	the	DT
cord-256444-grw5s2pf	153	19	fusion	fusion	NN
cord-256444-grw5s2pf	153	20	activity	activity	NN
cord-256444-grw5s2pf	153	21	of	of	IN
cord-256444-grw5s2pf	153	22	the	the	DT
cord-256444-grw5s2pf	153	23	A59	A59	NNP
cord-256444-grw5s2pf	153	24	strain	strain	NN
cord-256444-grw5s2pf	153	25	of	of	IN
cord-256444-grw5s2pf	153	26	MHV	MHV	NNP
cord-256444-grw5s2pf	153	27	was	be	VBD
cord-256444-grw5s2pf	153	28	not	not	RB
cord-256444-grw5s2pf	153	29	affected	affect	VBN
cord-256444-grw5s2pf	153	30	by	by	IN
cord-256444-grw5s2pf	153	31	this	this	DT
cord-256444-grw5s2pf	153	32	modification	modification	NN
cord-256444-grw5s2pf	153	33	.	.	.
cord-256444-grw5s2pf	154	1	(	(	-LRB-
cord-256444-grw5s2pf	154	2	6	6	CD
cord-256444-grw5s2pf	154	3	)	)	-RRB-
cord-256444-grw5s2pf	155	1	Some	some	DT
cord-256444-grw5s2pf	155	2	mutations	mutation	NNS
cord-256444-grw5s2pf	155	3	to	to	IN
cord-256444-grw5s2pf	155	4	cysteine	cysteine	NN
cord-256444-grw5s2pf	155	5	residues	residue	NNS
cord-256444-grw5s2pf	155	6	within	within	IN
cord-256444-grw5s2pf	155	7	the	the	DT
cord-256444-grw5s2pf	155	8	transmembrane	transmembrane	NN
cord-256444-grw5s2pf	155	9	domain	domain	NN
cord-256444-grw5s2pf	155	10	of	of	IN
cord-256444-grw5s2pf	155	11	S	S	NNP
cord-256444-grw5s2pf	155	12	adversely	adversely	RB
cord-256444-grw5s2pf	155	13	affected	affect	VBD
cord-256444-grw5s2pf	155	14	fusion	fusion	NN
cord-256444-grw5s2pf	155	15	,	,	,
cord-256444-grw5s2pf	155	16	suggesting	suggest	VBG
cord-256444-grw5s2pf	155	17	that	that	IN
cord-256444-grw5s2pf	155	18	the	the	DT
cord-256444-grw5s2pf	155	19	transmembrane	transmembrane	NN
cord-256444-grw5s2pf	155	20	domain	domain	NN
cord-256444-grw5s2pf	155	21	is	be	VBZ
cord-256444-grw5s2pf	155	22	involved	involve	VBN
cord-256444-grw5s2pf	155	23	in	in	IN
cord-256444-grw5s2pf	155	24	conformational	conformational	JJ
cord-256444-grw5s2pf	155	25	changes	change	NNS
cord-256444-grw5s2pf	155	26	that	that	WDT
cord-256444-grw5s2pf	155	27	are	be	VBP
cord-256444-grw5s2pf	155	28	associated	associate	VBN
cord-256444-grw5s2pf	155	29	with	with	IN
cord-256444-grw5s2pf	155	30	fusion	fusion	NN
cord-256444-grw5s2pf	155	31	activity	activity	NN
cord-256444-grw5s2pf	155	32	(	(	-LRB-
cord-256444-grw5s2pf	156	1	Bos	Bos	NNP
cord-256444-grw5s2pf	156	2	et	et	NNP
cord-256444-grw5s2pf	156	3	al	al	NNP
cord-256444-grw5s2pf	156	4	.	.	NNP
cord-256444-grw5s2pf	156	5	,	,	,
cord-256444-grw5s2pf	156	6	1995	1995	CD
cord-256444-grw5s2pf	156	7	)	)	-RRB-
cord-256444-grw5s2pf	156	8	.	.	.
cord-256444-grw5s2pf	157	1	These	these	DT
cord-256444-grw5s2pf	157	2	results	result	NNS
cord-256444-grw5s2pf	157	3	combined	combine	VBN
cord-256444-grw5s2pf	157	4	suggest	suggest	VBP
cord-256444-grw5s2pf	157	5	that	that	IN
cord-256444-grw5s2pf	157	6	the	the	DT
cord-256444-grw5s2pf	157	7	S2	S2	NNP
cord-256444-grw5s2pf	157	8	ectodomain	ectodomain	NNP
cord-256444-grw5s2pf	157	9	contains	contain	VBZ
cord-256444-grw5s2pf	157	10	the	the	DT
cord-256444-grw5s2pf	157	11	major	major	JJ
cord-256444-grw5s2pf	157	12	determinants	determinant	NNS
cord-256444-grw5s2pf	157	13	for	for	IN
cord-256444-grw5s2pf	157	14	membrane	membrane	NN
cord-256444-grw5s2pf	157	15	fusion	fusion	NN
cord-256444-grw5s2pf	157	16	;	;	:
cord-256444-grw5s2pf	157	17	however	however	RB
cord-256444-grw5s2pf	157	18	,	,	,
cord-256444-grw5s2pf	157	19	S2	S2	NNP
cord-256444-grw5s2pf	157	20	does	do	VBZ
cord-256444-grw5s2pf	157	21	not	not	RB
cord-256444-grw5s2pf	157	22	contain	contain	VB
cord-256444-grw5s2pf	157	23	hydrophobic	hydrophobic	JJ
cord-256444-grw5s2pf	157	24	domains	domain	NNS
cord-256444-grw5s2pf	157	25	typical	typical	JJ
cord-256444-grw5s2pf	157	26	of	of	IN
cord-256444-grw5s2pf	157	27	fusion	fusion	NN
cord-256444-grw5s2pf	157	28	proteins	protein	NNS
cord-256444-grw5s2pf	157	29	.	.	.
cord-256444-grw5s2pf	158	1	Thus	thus	RB
cord-256444-grw5s2pf	158	2	,	,	,
cord-256444-grw5s2pf	158	3	several	several	JJ
cord-256444-grw5s2pf	158	4	disparate	disparate	JJ
cord-256444-grw5s2pf	158	5	regions	region	NNS
cord-256444-grw5s2pf	158	6	,	,	,
cord-256444-grw5s2pf	158	7	including	include	VBG
cord-256444-grw5s2pf	158	8	some	some	DT
cord-256444-grw5s2pf	158	9	in	in	IN
cord-256444-grw5s2pf	158	10	the	the	DT
cord-256444-grw5s2pf	158	11	S1	s1	NN
cord-256444-grw5s2pf	158	12	,	,	,
cord-256444-grw5s2pf	158	13	may	may	MD
cord-256444-grw5s2pf	158	14	contribute	contribute	VB
cord-256444-grw5s2pf	158	15	to	to	IN
cord-256444-grw5s2pf	158	16	the	the	DT
cord-256444-grw5s2pf	158	17	fusion	fusion	NN
cord-256444-grw5s2pf	158	18	activity	activity	NN
cord-256444-grw5s2pf	158	19	,	,	,
cord-256444-grw5s2pf	158	20	probably	probably	RB
cord-256444-grw5s2pf	158	21	because	because	IN
cord-256444-grw5s2pf	158	22	some	some	DT
cord-256444-grw5s2pf	158	23	of	of	IN
cord-256444-grw5s2pf	158	24	these	these	DT
cord-256444-grw5s2pf	158	25	regions	region	NNS
cord-256444-grw5s2pf	158	26	are	be	VBP
cord-256444-grw5s2pf	158	27	juxtaposed	juxtapose	VBN
cord-256444-grw5s2pf	158	28	in	in	IN
cord-256444-grw5s2pf	158	29	the	the	DT
cord-256444-grw5s2pf	158	30	threedimensional	threedimensional	JJ
cord-256444-grw5s2pf	158	31	structure	structure	NN
cord-256444-grw5s2pf	158	32	or	or	CC
cord-256444-grw5s2pf	158	33	can	can	MD
cord-256444-grw5s2pf	158	34	affect	affect	VB
cord-256444-grw5s2pf	158	35	the	the	DT
cord-256444-grw5s2pf	158	36	overall	overall	JJ
cord-256444-grw5s2pf	158	37	conformation	conformation	NN
cord-256444-grw5s2pf	158	38	of	of	IN
cord-256444-grw5s2pf	158	39	the	the	DT
cord-256444-grw5s2pf	158	40	spikes	spike	NNS
cord-256444-grw5s2pf	158	41	.	.	.
cord-256444-grw5s2pf	159	1	Interestingly	interestingly	RB
cord-256444-grw5s2pf	159	2	,	,	,
cord-256444-grw5s2pf	159	3	monoclonal	monoclonal	JJ
cord-256444-grw5s2pf	159	4	antibody	antibody	NN
cord-256444-grw5s2pf	159	5	-	-	HYPH
cord-256444-grw5s2pf	159	6	resistant	resistant	JJ
cord-256444-grw5s2pf	159	7	mutants	mutant	NNS
cord-256444-grw5s2pf	159	8	of	of	IN
cord-256444-grw5s2pf	159	9	the	the	DT
cord-256444-grw5s2pf	159	10	JHM	JHM	NNP
cord-256444-grw5s2pf	159	11	strain	strain	VB
cord-256444-grw5s2pf	159	12	ofMHVselected	ofmhvselecte	VBN
cord-256444-grw5s2pf	159	13	with	with	IN
cord-256444-grw5s2pf	159	14	antibody	antibody	NN
cord-256444-grw5s2pf	159	15	11F	11f	CD
cord-256444-grw5s2pf	159	16	had	have	VBD
cord-256444-grw5s2pf	159	17	mutations	mutation	NNS
cord-256444-grw5s2pf	159	18	not	not	RB
cord-256444-grw5s2pf	159	19	a	a	DT
cord-256444-grw5s2pf	159	20	t	t	NN
cord-256444-grw5s2pf	160	1	the	the	DT
cord-256444-grw5s2pf	160	2	antibody	antibody	NN
cord-256444-grw5s2pf	160	3	-	-	HYPH
cord-256444-grw5s2pf	160	4	binding	bind	VBG
cord-256444-grw5s2pf	160	5	site	site	NN
cord-256444-grw5s2pf	160	6	(	(	-LRB-
cord-256444-grw5s2pf	160	7	residues	residue	NNS
cord-256444-grw5s2pf	160	8	33	33	CD
cord-256444-grw5s2pf	160	9	-	-	SYM
cord-256444-grw5s2pf	160	10	40	40	CD
cord-256444-grw5s2pf	160	11	of	of	IN
cord-256444-grw5s2pf	160	12	S	S	NNP
cord-256444-grw5s2pf	160	13	l	l	NNP
cord-256444-grw5s2pf	160	14	)	)	-RRB-
cord-256444-grw5s2pf	160	15	,	,	,
cord-256444-grw5s2pf	160	16	but	but	CC
cord-256444-grw5s2pf	160	17	at	at	IN
cord-256444-grw5s2pf	160	18	a	a	DT
cord-256444-grw5s2pf	160	19	distant	distant	JJ
cord-256444-grw5s2pf	160	20	site	site	NN
cord-256444-grw5s2pf	160	21	,	,	,
cord-256444-grw5s2pf	160	22	i.e.	i.e.	FW
cord-256444-grw5s2pf	160	23	,	,	,
cord-256444-grw5s2pf	160	24	residues	residue	NNS
cord-256444-grw5s2pf	160	25	1109	1109	CD
cord-256444-grw5s2pf	160	26	-	-	SYM
cord-256444-grw5s2pf	160	27	1116	1116	CD
cord-256444-grw5s2pf	160	28	in	in	IN
cord-256444-grw5s2pf	160	29	the	the	DT
cord-256444-grw5s2pf	160	30	S2	S2	NNP
cord-256444-grw5s2pf	160	31	domain	domain	NN
cord-256444-grw5s2pf	160	32	(	(	-LRB-
cord-256444-grw5s2pf	160	33	Grosse	Grosse	NNP
cord-256444-grw5s2pf	160	34	and	and	CC
cord-256444-grw5s2pf	160	35	Siddell	Siddell	NNP
cord-256444-grw5s2pf	160	36	,	,	,
cord-256444-grw5s2pf	160	37	1994	1994	CD
cord-256444-grw5s2pf	160	38	)	)	-RRB-
cord-256444-grw5s2pf	160	39	(	(	-LRB-
cord-256444-grw5s2pf	160	40	Fig	Fig	NNP
cord-256444-grw5s2pf	160	41	.	.	.
cord-256444-grw5s2pf	160	42	 	 	_SP
cord-256444-grw5s2pf	160	43	4	4	CD
cord-256444-grw5s2pf	160	44	)	)	-RRB-
cord-256444-grw5s2pf	160	45	,	,	,
cord-256444-grw5s2pf	160	46	suggesting	suggest	VBG
cord-256444-grw5s2pf	160	47	that	that	IN
cord-256444-grw5s2pf	160	48	S	S	NNP
cord-256444-grw5s2pf	160	49	is	be	VBZ
cord-256444-grw5s2pf	160	50	folded	fold	VBN
cord-256444-grw5s2pf	160	51	such	such	JJ
cord-256444-grw5s2pf	160	52	that	that	IN
cord-256444-grw5s2pf	160	53	regions	region	NNS
cord-256444-grw5s2pf	160	54	which	which	WDT
cord-256444-grw5s2pf	160	55	are	be	VBP
cord-256444-grw5s2pf	160	56	widely	widely	RB
cord-256444-grw5s2pf	160	57	separated	separate	VBN
cord-256444-grw5s2pf	160	58	in	in	IN
cord-256444-grw5s2pf	160	59	the	the	DT
cord-256444-grw5s2pf	160	60	linear	linear	JJ
cord-256444-grw5s2pf	160	61	sense	sense	NN
cord-256444-grw5s2pf	160	62	are	be	VBP
cord-256444-grw5s2pf	160	63	juxtaposed	juxtapose	VBN
cord-256444-grw5s2pf	160	64	to	to	TO
cord-256444-grw5s2pf	160	65	form	form	VB
cord-256444-grw5s2pf	160	66	functional	functional	JJ
cord-256444-grw5s2pf	160	67	domains	domain	NNS
cord-256444-grw5s2pf	160	68	.	.	.
cord-256444-grw5s2pf	161	1	Early	early	JJ
cord-256444-grw5s2pf	161	2	studies	study	NNS
cord-256444-grw5s2pf	161	3	of	of	IN
cord-256444-grw5s2pf	161	4	coronvirus	coronvirus	NNP
cord-256444-grw5s2pf	161	5	-	-	HYPH
cord-256444-grw5s2pf	161	6	induced	induce	VBN
cord-256444-grw5s2pf	161	7	cell	cell	NN
cord-256444-grw5s2pf	161	8	-	-	HYPH
cord-256444-grw5s2pf	161	9	cell	cell	NN
cord-256444-grw5s2pf	161	10	fusion	fusion	NN
cord-256444-grw5s2pf	161	11	suggested	suggest	VBD
cord-256444-grw5s2pf	161	12	that	that	IN
cord-256444-grw5s2pf	161	13	only	only	RB
cord-256444-grw5s2pf	161	14	cleaved	cleave	VBN
cord-256444-grw5s2pf	161	15	S	S	NNP
cord-256444-grw5s2pf	161	16	was	be	VBD
cord-256444-grw5s2pf	161	17	able	able	JJ
cord-256444-grw5s2pf	161	18	to	to	TO
cord-256444-grw5s2pf	161	19	promote	promote	VB
cord-256444-grw5s2pf	161	20	cell	cell	NN
cord-256444-grw5s2pf	161	21	fusion	fusion	NN
cord-256444-grw5s2pf	161	22	.	.	.
cord-256444-grw5s2pf	162	1	More	More	JJR
cord-256444-grw5s2pf	162	2	recent	recent	JJ
cord-256444-grw5s2pf	162	3	studies	study	NNS
cord-256444-grw5s2pf	162	4	in	in	IN
cord-256444-grw5s2pf	162	5	which	which	WDT
cord-256444-grw5s2pf	162	6	MHV	MHV	NNP
cord-256444-grw5s2pf	162	7	S	S	NNP
cord-256444-grw5s2pf	162	8	proteins	protein	NNS
cord-256444-grw5s2pf	162	9	with	with	IN
cord-256444-grw5s2pf	162	10	mutated	mutated	JJ
cord-256444-grw5s2pf	162	11	S	s	NN
cord-256444-grw5s2pf	162	12	1	1	CD
cord-256444-grw5s2pf	162	13	3	3	CD
cord-256444-grw5s2pf	162	14	2	2	CD
cord-256444-grw5s2pf	162	15	connecting	connect	VBG
cord-256444-grw5s2pf	162	16	peptides	peptide	NNS
cord-256444-grw5s2pf	162	17	were	be	VBD
cord-256444-grw5s2pf	162	18	expressed	express	VBN
cord-256444-grw5s2pf	162	19	have	have	VBP
cord-256444-grw5s2pf	162	20	shown	show	VBN
cord-256444-grw5s2pf	162	21	that	that	IN
cord-256444-grw5s2pf	162	22	cleavage	cleavage	NN
cord-256444-grw5s2pf	162	23	is	be	VBZ
cord-256444-grw5s2pf	162	24	not	not	RB
cord-256444-grw5s2pf	162	25	essential	essential	JJ
cord-256444-grw5s2pf	162	26	for	for	IN
cord-256444-grw5s2pf	162	27	fusogenic	fusogenic	JJ
cord-256444-grw5s2pf	162	28	activity	activity	NN
cord-256444-grw5s2pf	162	29	,	,	,
cord-256444-grw5s2pf	162	30	although	although	IN
cord-256444-grw5s2pf	162	31	cell	cell	NN
cord-256444-grw5s2pf	162	32	-	-	HYPH
cord-256444-grw5s2pf	162	33	cell	cell	NN
cord-256444-grw5s2pf	162	34	fusion	fusion	NN
cord-256444-grw5s2pf	162	35	is	be	VBZ
cord-256444-grw5s2pf	162	36	more	more	RBR
cord-256444-grw5s2pf	162	37	efficient	efficient	JJ
cord-256444-grw5s2pf	162	38	when	when	WRB
cord-256444-grw5s2pf	162	39	the	the	DT
cord-256444-grw5s2pf	162	40	S	S	NNP
cord-256444-grw5s2pf	162	41	protein	protein	NN
cord-256444-grw5s2pf	162	42	is	be	VBZ
cord-256444-grw5s2pf	162	43	cleaved	cleave	VBN
cord-256444-grw5s2pf	162	44	(	(	-LRB-
cord-256444-grw5s2pf	163	1	Stauber	Stauber	NNP
cord-256444-grw5s2pf	163	2	et	et	NNP
cord-256444-grw5s2pf	163	3	al	al	NNP
cord-256444-grw5s2pf	163	4	.	.	NNP
cord-256444-grw5s2pf	163	5	,	,	,
cord-256444-grw5s2pf	163	6	1993	1993	CD
cord-256444-grw5s2pf	163	7	;	;	:
cord-256444-grw5s2pf	163	8	Taguchi	Taguchi	NNP
cord-256444-grw5s2pf	163	9	,	,	,
cord-256444-grw5s2pf	163	10	1993	1993	CD
cord-256444-grw5s2pf	163	11	;	;	:
cord-256444-grw5s2pf	163	12	Bos	Bos	NNP
cord-256444-grw5s2pf	163	13	et	et	NNP
cord-256444-grw5s2pf	163	14	al	al	NNP
cord-256444-grw5s2pf	163	15	.	.	NNP
cord-256444-grw5s2pf	163	16	,	,	,
cord-256444-grw5s2pf	163	17	1995	1995	CD
cord-256444-grw5s2pf	163	18	)	)	-RRB-
cord-256444-grw5s2pf	163	19	.	.	.
cord-256444-grw5s2pf	164	1	Furthermore	furthermore	RB
cord-256444-grw5s2pf	164	2	,	,	,
cord-256444-grw5s2pf	164	3	naturally	naturally	RB
cord-256444-grw5s2pf	164	4	occurring	occur	VBG
cord-256444-grw5s2pf	164	5	mutants	mutant	NNS
cord-256444-grw5s2pf	164	6	of	of	IN
cord-256444-grw5s2pf	164	7	MHV	MHV	NNP
cord-256444-grw5s2pf	164	8	,	,	,
cord-256444-grw5s2pf	164	9	derived	derive	VBN
cord-256444-grw5s2pf	164	10	from	from	IN
cord-256444-grw5s2pf	164	11	persistently	persistently	RB
cord-256444-grw5s2pf	164	12	infected	infect	VBN
cord-256444-grw5s2pf	164	13	mouse	mouse	NN
cord-256444-grw5s2pf	164	14	cells	cell	NNS
cord-256444-grw5s2pf	164	15	,	,	,
cord-256444-grw5s2pf	164	16	which	which	WDT
cord-256444-grw5s2pf	164	17	are	be	VBP
cord-256444-grw5s2pf	164	18	defective	defective	JJ
cord-256444-grw5s2pf	164	19	in	in	IN
cord-256444-grw5s2pf	164	20	S	s	NN
cord-256444-grw5s2pf	164	21	cleavage	cleavage	NN
cord-256444-grw5s2pf	164	22	,	,	,
cord-256444-grw5s2pf	164	23	have	have	VBP
cord-256444-grw5s2pf	164	24	delayed	delay	VBN
cord-256444-grw5s2pf	164	25	fusion	fusion	NN
cord-256444-grw5s2pf	164	26	activity	activity	NN
cord-256444-grw5s2pf	164	27	(	(	-LRB-
cord-256444-grw5s2pf	164	28	Gombold	Gombold	NNP
cord-256444-grw5s2pf	164	29	et	et	NNP
cord-256444-grw5s2pf	164	30	al	al	NNP
cord-256444-grw5s2pf	164	31	.	.	NNP
cord-256444-grw5s2pf	164	32	,	,	,
cord-256444-grw5s2pf	164	33	1993	1993	CD
cord-256444-grw5s2pf	164	34	)	)	-RRB-
cord-256444-grw5s2pf	164	35	.	.	.
cord-256444-grw5s2pf	165	1	Expression	expression	NN
cord-256444-grw5s2pf	165	2	of	of	IN
cord-256444-grw5s2pf	165	3	the	the	DT
cord-256444-grw5s2pf	165	4	feline	feline	JJ
cord-256444-grw5s2pf	165	5	infectious	infectious	JJ
cord-256444-grw5s2pf	165	6	peritonitis	peritonitis	NN
cord-256444-grw5s2pf	165	7	virus	virus	NN
cord-256444-grw5s2pf	165	8	(	(	-LRB-
cord-256444-grw5s2pf	165	9	FIPV	FIPV	NNP
cord-256444-grw5s2pf	165	10	)	)	-RRB-
cord-256444-grw5s2pf	165	11	S	s	NN
cord-256444-grw5s2pf	165	12	protein	protein	NN
cord-256444-grw5s2pf	165	13	,	,	,
cord-256444-grw5s2pf	165	14	which	which	WDT
cord-256444-grw5s2pf	165	15	is	be	VBZ
cord-256444-grw5s2pf	165	16	not	not	RB
cord-256444-grw5s2pf	165	17	cleaved	cleave	VBN
cord-256444-grw5s2pf	165	18	a	a	DT
cord-256444-grw5s2pf	165	19	t	t	NN
cord-256444-grw5s2pf	165	20	all	all	DT
cord-256444-grw5s2pf	165	21	,	,	,
cord-256444-grw5s2pf	165	22	also	also	RB
cord-256444-grw5s2pf	165	23	resulted	result	VBD
cord-256444-grw5s2pf	165	24	in	in	IN
cord-256444-grw5s2pf	165	25	syncytia	syncytia	NN
cord-256444-grw5s2pf	165	26	formation	formation	NN
cord-256444-grw5s2pf	165	27	(	(	-LRB-
cord-256444-grw5s2pf	165	28	de	de	FW
cord-256444-grw5s2pf	165	29	Groot	Groot	NNP
cord-256444-grw5s2pf	165	30	et	et	FW
cord-256444-grw5s2pf	165	31	al	al	NNP
cord-256444-grw5s2pf	165	32	.	.	NNP
cord-256444-grw5s2pf	165	33	,	,	,
cord-256444-grw5s2pf	165	34	1989	1989	CD
cord-256444-grw5s2pf	165	35	)	)	-RRB-
cord-256444-grw5s2pf	165	36	.	.	.
cord-256444-grw5s2pf	166	1	These	these	DT
cord-256444-grw5s2pf	166	2	results	result	NNS
cord-256444-grw5s2pf	166	3	indicate	indicate	VBP
cord-256444-grw5s2pf	166	4	that	that	IN
cord-256444-grw5s2pf	166	5	S	s	NN
cord-256444-grw5s2pf	166	6	protein	protein	NN
cord-256444-grw5s2pf	166	7	cleavage	cleavage	NN
cord-256444-grw5s2pf	166	8	is	be	VBZ
cord-256444-grw5s2pf	166	9	not	not	RB
cord-256444-grw5s2pf	166	10	required	require	VBN
cord-256444-grw5s2pf	166	11	for	for	IN
cord-256444-grw5s2pf	166	12	but	but	CC
cord-256444-grw5s2pf	166	13	can	can	MD
cord-256444-grw5s2pf	166	14	enhance	enhance	VB
cord-256444-grw5s2pf	166	15	membrane	membrane	NN
cord-256444-grw5s2pf	166	16	fusion	fusion	NN
cord-256444-grw5s2pf	166	17	.	.	.
cord-256444-grw5s2pf	167	1	Whether	whether	IN
cord-256444-grw5s2pf	167	2	membrane	membrane	NN
cord-256444-grw5s2pf	167	3	fusion	fusion	NN
cord-256444-grw5s2pf	167	4	activity	activity	NN
cord-256444-grw5s2pf	167	5	,	,	,
cord-256444-grw5s2pf	167	6	as	as	IN
cord-256444-grw5s2pf	167	7	manifested	manifest	VBN
cord-256444-grw5s2pf	167	8	by	by	IN
cord-256444-grw5s2pf	167	9	syncytia	syncytia	NN
cord-256444-grw5s2pf	167	10	formation	formation	NN
cord-256444-grw5s2pf	167	11	,	,	,
cord-256444-grw5s2pf	167	12	is	be	VBZ
cord-256444-grw5s2pf	167	13	required	require	VBN
cord-256444-grw5s2pf	167	14	for	for	IN
cord-256444-grw5s2pf	167	15	viral	viral	JJ
cord-256444-grw5s2pf	167	16	infectivity	infectivity	NN
cord-256444-grw5s2pf	167	17	has	have	VBZ
cord-256444-grw5s2pf	167	18	not	not	RB
cord-256444-grw5s2pf	167	19	been	be	VBN
cord-256444-grw5s2pf	167	20	established	establish	VBN
cord-256444-grw5s2pf	167	21	.	.	.
cord-256444-grw5s2pf	168	1	There	there	EX
cord-256444-grw5s2pf	168	2	are	be	VBP
cord-256444-grw5s2pf	168	3	MHV	mhv	NN
cord-256444-grw5s2pf	168	4	strains	strain	NNS
cord-256444-grw5s2pf	168	5	(	(	-LRB-
cord-256444-grw5s2pf	168	6	e.g.	e.g.	RB
cord-256444-grw5s2pf	168	7	,	,	,
cord-256444-grw5s2pf	168	8	MHV-2	mhv-2	NN
cord-256444-grw5s2pf	168	9	)	)	-RRB-
cord-256444-grw5s2pf	168	10	that	that	WDT
cord-256444-grw5s2pf	168	11	do	do	VBP
cord-256444-grw5s2pf	168	12	not	not	RB
cord-256444-grw5s2pf	168	13	cause	cause	VB
cord-256444-grw5s2pf	168	14	syncytia	syncytia	NN
cord-256444-grw5s2pf	168	15	formation	formation	NN
cord-256444-grw5s2pf	168	16	in	in	IN
cord-256444-grw5s2pf	168	17	cultured	cultured	JJ
cord-256444-grw5s2pf	168	18	cells	cell	NNS
cord-256444-grw5s2pf	168	19	;	;	:
cord-256444-grw5s2pf	168	20	however	however	RB
cord-256444-grw5s2pf	168	21	,	,	,
cord-256444-grw5s2pf	168	22	these	these	DT
cord-256444-grw5s2pf	168	23	viruses	virus	NNS
cord-256444-grw5s2pf	168	24	may	may	MD
cord-256444-grw5s2pf	168	25	be	be	VB
cord-256444-grw5s2pf	168	26	able	able	JJ
cord-256444-grw5s2pf	168	27	to	to	TO
cord-256444-grw5s2pf	168	28	cause	cause	VB
cord-256444-grw5s2pf	168	29	virus	virus	NN
cord-256444-grw5s2pf	168	30	-	-	HYPH
cord-256444-grw5s2pf	168	31	cell	cell	NN
cord-256444-grw5s2pf	168	32	membrane	membrane	NN
cord-256444-grw5s2pf	168	33	fusion	fusion	NN
cord-256444-grw5s2pf	168	34	within	within	IN
cord-256444-grw5s2pf	168	35	the	the	DT
cord-256444-grw5s2pf	168	36	infected	infected	JJ
cord-256444-grw5s2pf	168	37	cells	cell	NNS
cord-256444-grw5s2pf	168	38	.	.	.
cord-256444-grw5s2pf	169	1	b.	b.	NNP
cord-256444-grw5s2pf	169	2	Receptor	Receptor	NNP
cord-256444-grw5s2pf	169	3	Binding	Binding	NNP
cord-256444-grw5s2pf	169	4	.	.	.
cord-256444-grw5s2pf	170	1	Monoclonal	monoclonal	JJ
cord-256444-grw5s2pf	170	2	antibodies	antibody	NNS
cord-256444-grw5s2pf	170	3	(	(	-LRB-
cord-256444-grw5s2pf	170	4	MAb	MAb	NNS
cord-256444-grw5s2pf	170	5	)	)	-RRB-
cord-256444-grw5s2pf	170	6	against	against	IN
cord-256444-grw5s2pf	170	7	the	the	DT
cord-256444-grw5s2pf	170	8	S	S	NNP
cord-256444-grw5s2pf	170	9	protein	protein	NN
cord-256444-grw5s2pf	170	10	of	of	IN
cord-256444-grw5s2pf	170	11	most	most	JJS
cord-256444-grw5s2pf	170	12	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	170	13	can	can	MD
cord-256444-grw5s2pf	170	14	neutralize	neutralize	VB
cord-256444-grw5s2pf	170	15	viral	viral	JJ
cord-256444-grw5s2pf	170	16	infectivity	infectivity	NN
cord-256444-grw5s2pf	170	17	;	;	:
cord-256444-grw5s2pf	170	18	thus	thus	RB
cord-256444-grw5s2pf	170	19	,	,	,
cord-256444-grw5s2pf	170	20	it	-PRON-	PRP
cord-256444-grw5s2pf	170	21	is	be	VBZ
cord-256444-grw5s2pf	170	22	assumed	assume	VBN
cord-256444-grw5s2pf	170	23	that	that	IN
cord-256444-grw5s2pf	170	24	the	the	DT
cord-256444-grw5s2pf	170	25	S	S	NNP
cord-256444-grw5s2pf	170	26	protein	protein	NN
cord-256444-grw5s2pf	170	27	mediates	mediate	VBZ
cord-256444-grw5s2pf	170	28	virus	virus	NN
cord-256444-grw5s2pf	170	29	binding	bind	VBG
cord-256444-grw5s2pf	170	30	to	to	IN
cord-256444-grw5s2pf	170	31	the	the	DT
cord-256444-grw5s2pf	170	32	receptors	receptor	NNS
cord-256444-grw5s2pf	170	33	on	on	IN
cord-256444-grw5s2pf	170	34	target	target	NN
cord-256444-grw5s2pf	170	35	cells	cell	NNS
cord-256444-grw5s2pf	170	36	.	.	.
cord-256444-grw5s2pf	171	1	Indeed	indeed	RB
cord-256444-grw5s2pf	171	2	,	,	,
cord-256444-grw5s2pf	171	3	the	the	DT
cord-256444-grw5s2pf	171	4	S	S	NNP
cord-256444-grw5s2pf	171	5	protein	protein	NN
cord-256444-grw5s2pf	171	6	or	or	CC
cord-256444-grw5s2pf	171	7	a	a	DT
cord-256444-grw5s2pf	171	8	portion	portion	NN
cord-256444-grw5s2pf	171	9	of	of	IN
cord-256444-grw5s2pf	171	10	it	-PRON-	PRP
cord-256444-grw5s2pf	171	11	can	can	MD
cord-256444-grw5s2pf	171	12	bind	bind	VB
cord-256444-grw5s2pf	171	13	to	to	IN
cord-256444-grw5s2pf	171	14	the	the	DT
cord-256444-grw5s2pf	171	15	viral	viral	JJ
cord-256444-grw5s2pf	171	16	receptor	receptor	NN
cord-256444-grw5s2pf	171	17	molecules	molecule	NNS
cord-256444-grw5s2pf	171	18	in	in	IN
cord-256444-grw5s2pf	171	19	uitro	uitro	NNP
cord-256444-grw5s2pf	171	20	.	.	.
cord-256444-grw5s2pf	172	1	This	this	DT
cord-256444-grw5s2pf	172	2	has	have	VBZ
cord-256444-grw5s2pf	172	3	been	be	VBN
cord-256444-grw5s2pf	172	4	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	172	5	for	for	IN
cord-256444-grw5s2pf	172	6	MHV	MHV	NNP
cord-256444-grw5s2pf	172	7	and	and	CC
cord-256444-grw5s2pf	172	8	TGEV	TGEV	NNP
cord-256444-grw5s2pf	172	9	S	S	NNP
cord-256444-grw5s2pf	172	10	proteins	protein	NNS
cord-256444-grw5s2pf	172	11	(	(	-LRB-
cord-256444-grw5s2pf	172	12	Godet	Godet	NNP
cord-256444-grw5s2pf	172	13	et	et	NNP
cord-256444-grw5s2pf	172	14	al	al	NNP
cord-256444-grw5s2pf	172	15	.	.	NNP
cord-256444-grw5s2pf	172	16	,	,	,
cord-256444-grw5s2pf	172	17	1994	1994	CD
cord-256444-grw5s2pf	172	18	;	;	:
cord-256444-grw5s2pf	172	19	Kubo	Kubo	NNP
cord-256444-grw5s2pf	172	20	et	et	NNP
cord-256444-grw5s2pf	172	21	al	al	NNP
cord-256444-grw5s2pf	172	22	.	.	NNP
cord-256444-grw5s2pf	172	23	,	,	,
cord-256444-grw5s2pf	172	24	1994	1994	CD
cord-256444-grw5s2pf	172	25	)	)	-RRB-
cord-256444-grw5s2pf	172	26	.	.	.
cord-256444-grw5s2pf	173	1	The	the	DT
cord-256444-grw5s2pf	173	2	binding	bind	VBG
cord-256444-grw5s2pf	173	3	domain	domain	NN
cord-256444-grw5s2pf	173	4	has	have	VBZ
cord-256444-grw5s2pf	173	5	been	be	VBN
cord-256444-grw5s2pf	173	6	mapped	map	VBN
cord-256444-grw5s2pf	173	7	to	to	IN
cord-256444-grw5s2pf	173	8	the	the	DT
cord-256444-grw5s2pf	173	9	N	N	NNP
cord-256444-grw5s2pf	173	10	-	-	HYPH
cord-256444-grw5s2pf	173	11	terminal	terminal	NN
cord-256444-grw5s2pf	173	12	330	330	CD
cord-256444-grw5s2pf	173	13	amino	amino	NN
cord-256444-grw5s2pf	173	14	acids	acid	NNS
cord-256444-grw5s2pf	173	15	of	of	IN
cord-256444-grw5s2pf	173	16	MHV	MHV	NNP
cord-256444-grw5s2pf	173	17	S1	S1	NNP
cord-256444-grw5s2pf	173	18	protein	protein	NN
cord-256444-grw5s2pf	173	19	.	.	.
cord-256444-grw5s2pf	174	1	Site	site	NN
cord-256444-grw5s2pf	174	2	-	-	HYPH
cord-256444-grw5s2pf	174	3	directed	direct	VBN
cord-256444-grw5s2pf	174	4	mutagenesis	mutagenesis	NN
cord-256444-grw5s2pf	174	5	of	of	IN
cord-256444-grw5s2pf	174	6	this	this	DT
cord-256444-grw5s2pf	174	7	region	region	NN
cord-256444-grw5s2pf	174	8	showed	show	VBD
cord-256444-grw5s2pf	174	9	that	that	IN
cord-256444-grw5s2pf	174	10	mutations	mutation	NNS
cord-256444-grw5s2pf	174	11	of	of	IN
cord-256444-grw5s2pf	174	12	the	the	DT
cord-256444-grw5s2pf	174	13	residues	residue	NNS
cord-256444-grw5s2pf	174	14	at	at	IN
cord-256444-grw5s2pf	174	15	position	position	NN
cord-256444-grw5s2pf	174	16	62	62	CD
cord-256444-grw5s2pf	174	17	and	and	CC
cord-256444-grw5s2pf	174	18	positions	position	VBZ
cord-256444-grw5s2pf	174	19	212	212	CD
cord-256444-grw5s2pf	174	20	,	,	,
cord-256444-grw5s2pf	174	21	214	214	CD
cord-256444-grw5s2pf	174	22	,	,	,
cord-256444-grw5s2pf	174	23	and	and	CC
cord-256444-grw5s2pf	174	24	216	216	CD
cord-256444-grw5s2pf	174	25	abolished	abolish	VBD
cord-256444-grw5s2pf	174	26	the	the	DT
cord-256444-grw5s2pf	174	27	binding	binding	NN
cord-256444-grw5s2pf	174	28	of	of	IN
cord-256444-grw5s2pf	174	29	the	the	DT
cord-256444-grw5s2pf	174	30	protein	protein	NN
cord-256444-grw5s2pf	174	31	to	to	IN
cord-256444-grw5s2pf	174	32	the	the	DT
cord-256444-grw5s2pf	174	33	receptor	receptor	NN
cord-256444-grw5s2pf	174	34	(	(	-LRB-
cord-256444-grw5s2pf	174	35	Suzuki	Suzuki	NNP
cord-256444-grw5s2pf	174	36	and	and	CC
cord-256444-grw5s2pf	174	37	Taguchi	Taguchi	NNP
cord-256444-grw5s2pf	174	38	,	,	,
cord-256444-grw5s2pf	174	39	19961	19961	CD
cord-256444-grw5s2pf	174	40	,	,	,
cord-256444-grw5s2pf	174	41	suggesting	suggest	VBG
cord-256444-grw5s2pf	174	42	that	that	IN
cord-256444-grw5s2pf	174	43	the	the	DT
cord-256444-grw5s2pf	174	44	receptor	receptor	NN
cord-256444-grw5s2pf	174	45	-	-	HYPH
cord-256444-grw5s2pf	174	46	binding	bind	VBG
cord-256444-grw5s2pf	174	47	site	site	NN
cord-256444-grw5s2pf	174	48	might	may	MD
cord-256444-grw5s2pf	174	49	comprise	comprise	VB
cord-256444-grw5s2pf	174	50	discontiguous	discontiguous	JJ
cord-256444-grw5s2pf	174	51	regions	region	NNS
cord-256444-grw5s2pf	174	52	in	in	IN
cord-256444-grw5s2pf	174	53	the	the	DT
cord-256444-grw5s2pf	174	54	linear	linear	JJ
cord-256444-grw5s2pf	174	55	sense	sense	NN
cord-256444-grw5s2pf	174	56	.	.	.
cord-256444-grw5s2pf	175	1	The	the	DT
cord-256444-grw5s2pf	175	2	S2	s2	NN
cord-256444-grw5s2pf	175	3	subunit	subunit	NN
cord-256444-grw5s2pf	175	4	is	be	VBZ
cord-256444-grw5s2pf	175	5	not	not	RB
cord-256444-grw5s2pf	175	6	involved	involve	VBN
cord-256444-grw5s2pf	175	7	in	in	IN
cord-256444-grw5s2pf	175	8	receptor	receptor	NN
cord-256444-grw5s2pf	175	9	binding	binding	NN
cord-256444-grw5s2pf	175	10	(	(	-LRB-
cord-256444-grw5s2pf	175	11	Taguchi	Taguchi	NNP
cord-256444-grw5s2pf	175	12	,	,	,
cord-256444-grw5s2pf	175	13	1995	1995	CD
cord-256444-grw5s2pf	175	14	)	)	-RRB-
cord-256444-grw5s2pf	175	15	.	.	.
cord-256444-grw5s2pf	176	1	The	the	DT
cord-256444-grw5s2pf	176	2	receptor	receptor	NN
cord-256444-grw5s2pf	176	3	-	-	HYPH
cord-256444-grw5s2pf	176	4	binding	bind	VBG
cord-256444-grw5s2pf	176	5	sites	site	NNS
cord-256444-grw5s2pf	176	6	of	of	IN
cord-256444-grw5s2pf	176	7	TGEV	TGEV	NNP
cord-256444-grw5s2pf	176	8	S	S	NNP
cord-256444-grw5s2pf	176	9	protein	protein	NN
cord-256444-grw5s2pf	176	10	have	have	VBP
cord-256444-grw5s2pf	176	11	been	be	VBN
cord-256444-grw5s2pf	176	12	mapped	map	VBN
cord-256444-grw5s2pf	176	13	to	to	IN
cord-256444-grw5s2pf	176	14	a	a	DT
cord-256444-grw5s2pf	176	15	223-residue	223-residue	CD
cord-256444-grw5s2pf	176	16	region	region	NN
cord-256444-grw5s2pf	176	17	(	(	-LRB-
cord-256444-grw5s2pf	176	18	aa	aa	NNP
cord-256444-grw5s2pf	176	19	506	506	CD
cord-256444-grw5s2pf	176	20	-	-	HYPH
cord-256444-grw5s2pf	176	21	729	729	CD
cord-256444-grw5s2pf	176	22	)	)	-RRB-
cord-256444-grw5s2pf	176	23	of	of	IN
cord-256444-grw5s2pf	176	24	the	the	DT
cord-256444-grw5s2pf	176	25	S1	s1	NN
cord-256444-grw5s2pf	176	26	(	(	-LRB-
cord-256444-grw5s2pf	176	27	Godet	Godet	NNP
cord-256444-grw5s2pf	176	28	et	et	NNP
cord-256444-grw5s2pf	176	29	al	al	NNP
cord-256444-grw5s2pf	176	30	.	.	NNP
cord-256444-grw5s2pf	176	31	,	,	,
cord-256444-grw5s2pf	176	32	19941	19941	CD
cord-256444-grw5s2pf	176	33	,	,	,
cord-256444-grw5s2pf	176	34	which	which	WDT
cord-256444-grw5s2pf	176	35	overlaps	overlap	VBZ
cord-256444-grw5s2pf	176	36	with	with	IN
cord-256444-grw5s2pf	176	37	a	a	DT
cord-256444-grw5s2pf	176	38	n	n	NN
cord-256444-grw5s2pf	176	39	epitope	epitope	NN
cord-256444-grw5s2pf	176	40	for	for	IN
cord-256444-grw5s2pf	176	41	a	a	DT
cord-256444-grw5s2pf	176	42	neutralizing	neutralize	VBG
cord-256444-grw5s2pf	176	43	MAb	MAb	NNS
cord-256444-grw5s2pf	176	44	.	.	.
cord-256444-grw5s2pf	177	1	This	this	DT
cord-256444-grw5s2pf	177	2	neutralizing	neutralize	VBG
cord-256444-grw5s2pf	177	3	MAb	MAb	NNS
cord-256444-grw5s2pf	177	4	was	be	VBD
cord-256444-grw5s2pf	177	5	able	able	JJ
cord-256444-grw5s2pf	177	6	to	to	TO
cord-256444-grw5s2pf	177	7	block	block	VB
cord-256444-grw5s2pf	177	8	the	the	DT
cord-256444-grw5s2pf	177	9	binding	binding	NN
cord-256444-grw5s2pf	177	10	of	of	IN
cord-256444-grw5s2pf	177	11	the	the	DT
cord-256444-grw5s2pf	177	12	223-residue	223-residue	CD
cord-256444-grw5s2pf	177	13	polypeptide	polypeptide	NN
cord-256444-grw5s2pf	177	14	to	to	IN
cord-256444-grw5s2pf	177	15	the	the	DT
cord-256444-grw5s2pf	177	16	receptor	receptor	NN
cord-256444-grw5s2pf	177	17	;	;	:
cord-256444-grw5s2pf	177	18	conversely	conversely	RB
cord-256444-grw5s2pf	177	19	,	,	,
cord-256444-grw5s2pf	177	20	the	the	DT
cord-256444-grw5s2pf	177	21	receptor	receptor	NN
cord-256444-grw5s2pf	177	22	did	do	VBD
cord-256444-grw5s2pf	177	23	not	not	RB
cord-256444-grw5s2pf	177	24	block	block	VB
cord-256444-grw5s2pf	177	25	the	the	DT
cord-256444-grw5s2pf	177	26	binding	binding	NN
cord-256444-grw5s2pf	177	27	of	of	IN
cord-256444-grw5s2pf	177	28	the	the	DT
cord-256444-grw5s2pf	177	29	MAb	MAb	NNS
cord-256444-grw5s2pf	177	30	to	to	IN
cord-256444-grw5s2pf	177	31	this	this	DT
cord-256444-grw5s2pf	177	32	polypeptide	polypeptide	NN
cord-256444-grw5s2pf	177	33	,	,	,
cord-256444-grw5s2pf	177	34	suggesting	suggest	VBG
cord-256444-grw5s2pf	177	35	that	that	IN
cord-256444-grw5s2pf	177	36	the	the	DT
cord-256444-grw5s2pf	177	37	receptor	receptor	NN
cord-256444-grw5s2pf	177	38	-	-	HYPH
cord-256444-grw5s2pf	177	39	binding	bind	VBG
cord-256444-grw5s2pf	177	40	determinants	determinant	NNS
cord-256444-grw5s2pf	177	41	and	and	CC
cord-256444-grw5s2pf	177	42	the	the	DT
cord-256444-grw5s2pf	177	43	neutralizing	neutralize	VBG
cord-256444-grw5s2pf	177	44	epitopes	epitope	NNS
cord-256444-grw5s2pf	177	45	are	be	VBP
cord-256444-grw5s2pf	177	46	distinct	distinct	JJ
cord-256444-grw5s2pf	177	47	and	and	CC
cord-256444-grw5s2pf	177	48	are	be	VBP
cord-256444-grw5s2pf	177	49	part	part	NN
cord-256444-grw5s2pf	177	50	of	of	IN
cord-256444-grw5s2pf	177	51	a	a	DT
cord-256444-grw5s2pf	177	52	domain	domain	NN
cord-256444-grw5s2pf	177	53	of	of	IN
cord-256444-grw5s2pf	177	54	S	S	NNP
cord-256444-grw5s2pf	177	55	whose	whose	WP$
cord-256444-grw5s2pf	177	56	configuration	configuration	NN
cord-256444-grw5s2pf	177	57	is	be	VBZ
cord-256444-grw5s2pf	177	58	independent	independent	JJ
cord-256444-grw5s2pf	177	59	of	of	IN
cord-256444-grw5s2pf	177	60	the	the	DT
cord-256444-grw5s2pf	177	61	remainder	remainder	NN
cord-256444-grw5s2pf	177	62	of	of	IN
cord-256444-grw5s2pf	177	63	the	the	DT
cord-256444-grw5s2pf	177	64	S	S	NNP
cord-256444-grw5s2pf	177	65	protein	protein	NN
cord-256444-grw5s2pf	177	66	.	.	.
cord-256444-grw5s2pf	178	1	S	s	NN
cord-256444-grw5s2pf	178	2	proteins	protein	NNS
cord-256444-grw5s2pf	178	3	of	of	IN
cord-256444-grw5s2pf	178	4	BCV	BCV	NNP
cord-256444-grw5s2pf	178	5	and	and	CC
cord-256444-grw5s2pf	179	1	HCV	HCV	NNP
cord-256444-grw5s2pf	179	2	-	-	HYPH
cord-256444-grw5s2pf	179	3	OC43	OC43	NNP
cord-256444-grw5s2pf	179	4	bind	bind	VB
cord-256444-grw5s2pf	179	5	to	to	IN
cord-256444-grw5s2pf	179	6	9-O	9-o	CD
cord-256444-grw5s2pf	179	7	-	-	HYPH
cord-256444-grw5s2pf	179	8	acetylneuraminic	acetylneuraminic	JJ
cord-256444-grw5s2pf	179	9	acid	acid	NN
cord-256444-grw5s2pf	180	1	(	(	-LRB-
cord-256444-grw5s2pf	180	2	Schultze	Schultze	NNP
cord-256444-grw5s2pf	180	3	et	et	NNP
cord-256444-grw5s2pf	180	4	al	al	NNP
cord-256444-grw5s2pf	180	5	.	.	NNP
cord-256444-grw5s2pf	180	6	,	,	,
cord-256444-grw5s2pf	180	7	1991a	1991a	CD
cord-256444-grw5s2pf	180	8	)	)	-RRB-
cord-256444-grw5s2pf	180	9	;	;	:
cord-256444-grw5s2pf	180	10	this	this	DT
cord-256444-grw5s2pf	180	11	binding	binding	NN
cord-256444-grw5s2pf	180	12	is	be	VBZ
cord-256444-grw5s2pf	180	13	required	require	VBN
cord-256444-grw5s2pf	180	14	for	for	IN
cord-256444-grw5s2pf	180	15	viral	viral	JJ
cord-256444-grw5s2pf	180	16	infection	infection	NN
cord-256444-grw5s2pf	180	17	.	.	.
cord-256444-grw5s2pf	181	1	The	the	DT
cord-256444-grw5s2pf	181	2	significance	significance	NN
cord-256444-grw5s2pf	181	3	of	of	IN
cord-256444-grw5s2pf	181	4	this	this	DT
cord-256444-grw5s2pf	181	5	binding	binding	NN
cord-256444-grw5s2pf	181	6	will	will	MD
cord-256444-grw5s2pf	181	7	be	be	VB
cord-256444-grw5s2pf	181	8	discussed	discuss	VBN
cord-256444-grw5s2pf	181	9	in	in	IN
cord-256444-grw5s2pf	181	10	Section	section	NN
cord-256444-grw5s2pf	181	11	V	v	NN
cord-256444-grw5s2pf	181	12	,	,	,
cord-256444-grw5s2pf	181	13	B	b	NN
cord-256444-grw5s2pf	181	14	on	on	IN
cord-256444-grw5s2pf	181	15	virus	virus	NN
cord-256444-grw5s2pf	181	16	attachment	attachment	NN
cord-256444-grw5s2pf	181	17	.	.	.
cord-256444-grw5s2pf	182	1	Intriguingly	intriguingly	RB
cord-256444-grw5s2pf	182	2	,	,	,
cord-256444-grw5s2pf	182	3	several	several	JJ
cord-256444-grw5s2pf	182	4	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	182	5	S	s	NN
cord-256444-grw5s2pf	182	6	proteins	protein	NNS
cord-256444-grw5s2pf	182	7	share	share	VBP
cord-256444-grw5s2pf	182	8	some	some	DT
cord-256444-grw5s2pf	182	9	sequence	sequence	NN
cord-256444-grw5s2pf	182	10	identity	identity	NN
cord-256444-grw5s2pf	182	11	with	with	IN
cord-256444-grw5s2pf	182	12	the	the	DT
cord-256444-grw5s2pf	182	13	receptor	receptor	NN
cord-256444-grw5s2pf	182	14	for	for	IN
cord-256444-grw5s2pf	182	15	the	the	DT
cord-256444-grw5s2pf	182	16	Fc	Fc	NNP
cord-256444-grw5s2pf	182	17	fragment	fragment	NN
cord-256444-grw5s2pf	182	18	of	of	IN
cord-256444-grw5s2pf	182	19	mammalian	mammalian	JJ
cord-256444-grw5s2pf	182	20	immunoglobulins	immunoglobulin	NNS
cord-256444-grw5s2pf	182	21	(	(	-LRB-
cord-256444-grw5s2pf	182	22	Fcy	Fcy	NNP
cord-256444-grw5s2pf	182	23	receptor	receptor	NN
cord-256444-grw5s2pf	182	24	)	)	-RRB-
cord-256444-grw5s2pf	182	25	.	.	.
cord-256444-grw5s2pf	183	1	Thus	thus	RB
cord-256444-grw5s2pf	183	2	,	,	,
cord-256444-grw5s2pf	183	3	MAb	MAb	NNS
cord-256444-grw5s2pf	183	4	to	to	IN
cord-256444-grw5s2pf	183	5	the	the	DT
cord-256444-grw5s2pf	183	6	Fcy	Fcy	NNP
cord-256444-grw5s2pf	183	7	receptor	receptor	NN
cord-256444-grw5s2pf	183	8	could	could	MD
cord-256444-grw5s2pf	183	9	immunoprecipitate	immunoprecipitate	VB
cord-256444-grw5s2pf	183	10	S	S	NNP
cord-256444-grw5s2pf	183	11	protein	protein	NN
cord-256444-grw5s2pf	183	12	from	from	IN
cord-256444-grw5s2pf	183	13	the	the	DT
cord-256444-grw5s2pf	183	14	MHV	MHV	NNP
cord-256444-grw5s2pf	183	15	-	-	HYPH
cord-256444-grw5s2pf	183	16	infected	infect	VBN
cord-256444-grw5s2pf	183	17	cells	cell	NNS
cord-256444-grw5s2pf	183	18	,	,	,
cord-256444-grw5s2pf	183	19	and	and	CC
cord-256444-grw5s2pf	183	20	S	S	NNP
cord-256444-grw5s2pf	183	21	could	could	MD
cord-256444-grw5s2pf	183	22	bind	bind	VB
cord-256444-grw5s2pf	183	23	to	to	IN
cord-256444-grw5s2pf	183	24	the	the	DT
cord-256444-grw5s2pf	183	25	Fc	Fc	NNP
cord-256444-grw5s2pf	183	26	fragment	fragment	NN
cord-256444-grw5s2pf	183	27	of	of	IN
cord-256444-grw5s2pf	183	28	immunoglobulin	immunoglobulin	NN
cord-256444-grw5s2pf	183	29	.	.	.
cord-256444-grw5s2pf	184	1	This	this	DT
cord-256444-grw5s2pf	184	2	molecular	molecular	JJ
cord-256444-grw5s2pf	184	3	mimicry	mimicry	NN
cord-256444-grw5s2pf	184	4	was	be	VBD
cord-256444-grw5s2pf	184	5	first	first	RB
cord-256444-grw5s2pf	184	6	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	184	7	for	for	IN
cord-256444-grw5s2pf	184	8	MHV	MHV	NNP
cord-256444-grw5s2pf	184	9	and	and	CC
cord-256444-grw5s2pf	184	10	,	,	,
cord-256444-grw5s2pf	184	11	more	more	RBR
cord-256444-grw5s2pf	184	12	recently	recently	RB
cord-256444-grw5s2pf	184	13	,	,	,
cord-256444-grw5s2pf	184	14	for	for	IN
cord-256444-grw5s2pf	184	15	BCV	BCV	NNP
cord-256444-grw5s2pf	184	16	and	and	CC
cord-256444-grw5s2pf	184	17	TGEV	TGEV	NNP
cord-256444-grw5s2pf	184	18	as	as	RB
cord-256444-grw5s2pf	184	19	well	well	RB
cord-256444-grw5s2pf	185	1	(	(	-LRB-
cord-256444-grw5s2pf	185	2	Oleszak	Oleszak	NNP
cord-256444-grw5s2pf	185	3	and	and	CC
cord-256444-grw5s2pf	185	4	Leibowitz	Leibowitz	NNP
cord-256444-grw5s2pf	185	5	,	,	,
cord-256444-grw5s2pf	185	6	1960	1960	CD
cord-256444-grw5s2pf	185	7	;	;	:
cord-256444-grw5s2pf	185	8	Oleszaket	Oleszaket	NNP
cord-256444-grw5s2pf	185	9	al	al	NNP
cord-256444-grw5s2pf	185	10	.	.	NNP
cord-256444-grw5s2pf	185	11	,	,	,
cord-256444-grw5s2pf	185	12	1992	1992	CD
cord-256444-grw5s2pf	185	13	Oleszaket	Oleszaket	NNP
cord-256444-grw5s2pf	185	14	al	al	NNP
cord-256444-grw5s2pf	185	15	.	.	NNP
cord-256444-grw5s2pf	185	16	,	,	,
cord-256444-grw5s2pf	185	17	,	,	,
cord-256444-grw5s2pf	185	18	1995	1995	CD
cord-256444-grw5s2pf	185	19	.	.	.
cord-256444-grw5s2pf	186	1	It	-PRON-	PRP
cord-256444-grw5s2pf	186	2	may	may	MD
cord-256444-grw5s2pf	186	3	play	play	VB
cord-256444-grw5s2pf	186	4	a	a	DT
cord-256444-grw5s2pf	186	5	role	role	NN
cord-256444-grw5s2pf	186	6	in	in	IN
cord-256444-grw5s2pf	186	7	modulating	modulate	VBG
cord-256444-grw5s2pf	186	8	viral	viral	JJ
cord-256444-grw5s2pf	186	9	pathogenicity	pathogenicity	NN
cord-256444-grw5s2pf	186	10	.	.	.
cord-256444-grw5s2pf	187	1	This	this	DT
cord-256444-grw5s2pf	187	2	potential	potential	JJ
cord-256444-grw5s2pf	187	3	function	function	NN
cord-256444-grw5s2pf	187	4	is	be	VBZ
cord-256444-grw5s2pf	187	5	significant	significant	JJ
cord-256444-grw5s2pf	187	6	because	because	IN
cord-256444-grw5s2pf	187	7	expression	expression	NN
cord-256444-grw5s2pf	187	8	of	of	IN
cord-256444-grw5s2pf	187	9	the	the	DT
cord-256444-grw5s2pf	187	10	S	S	NNP
cord-256444-grw5s2pf	187	11	protein	protein	NN
cord-256444-grw5s2pf	187	12	in	in	IN
cord-256444-grw5s2pf	187	13	the	the	DT
cord-256444-grw5s2pf	187	14	infected	infected	JJ
cord-256444-grw5s2pf	187	15	cells	cell	NNS
cord-256444-grw5s2pf	187	16	induces	induce	VBZ
cord-256444-grw5s2pf	187	17	not	not	RB
cord-256444-grw5s2pf	187	18	only	only	RB
cord-256444-grw5s2pf	187	19	humoral	humoral	JJ
cord-256444-grw5s2pf	187	20	antibodies	antibody	NNS
cord-256444-grw5s2pf	187	21	but	but	CC
cord-256444-grw5s2pf	187	22	cellular	cellular	JJ
cord-256444-grw5s2pf	187	23	immunity	immunity	NN
cord-256444-grw5s2pf	187	24	as	as	RB
cord-256444-grw5s2pf	187	25	well	well	RB
cord-256444-grw5s2pf	187	26	(	(	-LRB-
cord-256444-grw5s2pf	187	27	Welsh	Welsh	NNP
cord-256444-grw5s2pf	187	28	et	et	NNP
cord-256444-grw5s2pf	187	29	al	al	NNP
cord-256444-grw5s2pf	187	30	.	.	NNP
cord-256444-grw5s2pf	187	31	,	,	,
cord-256444-grw5s2pf	187	32	1986	1986	CD
cord-256444-grw5s2pf	187	33	)	)	-RRB-
cord-256444-grw5s2pf	187	34	;	;	:
cord-256444-grw5s2pf	187	35	the	the	DT
cord-256444-grw5s2pf	187	36	potential	potential	JJ
cord-256444-grw5s2pf	187	37	binding	binding	NN
cord-256444-grw5s2pf	187	38	of	of	IN
cord-256444-grw5s2pf	187	39	S	S	NNP
cord-256444-grw5s2pf	187	40	to	to	IN
cord-256444-grw5s2pf	187	41	the	the	DT
cord-256444-grw5s2pf	187	42	Fc	Fc	NNP
cord-256444-grw5s2pf	187	43	fragment	fragment	NN
cord-256444-grw5s2pf	187	44	of	of	IN
cord-256444-grw5s2pf	187	45	immunoglobulin	immunoglobulin	NN
cord-256444-grw5s2pf	187	46	may	may	MD
cord-256444-grw5s2pf	187	47	modulate	modulate	VB
cord-256444-grw5s2pf	187	48	these	these	DT
cord-256444-grw5s2pf	187	49	immune	immune	JJ
cord-256444-grw5s2pf	187	50	responses	response	NNS
cord-256444-grw5s2pf	187	51	.	.	.
cord-256444-grw5s2pf	188	1	The	the	DT
cord-256444-grw5s2pf	188	2	M	M	NNP
cord-256444-grw5s2pf	188	3	protein	protein	NN
cord-256444-grw5s2pf	188	4	is	be	VBZ
cord-256444-grw5s2pf	188	5	one	one	CD
cord-256444-grw5s2pf	188	6	of	of	IN
cord-256444-grw5s2pf	188	7	only	only	RB
cord-256444-grw5s2pf	188	8	two	two	CD
cord-256444-grw5s2pf	188	9	of	of	IN
cord-256444-grw5s2pf	188	10	the	the	DT
cord-256444-grw5s2pf	188	11	structural	structural	JJ
cord-256444-grw5s2pf	188	12	proteins	protein	NNS
cord-256444-grw5s2pf	188	13	[	[	-LRB-
cord-256444-grw5s2pf	188	14	the	the	DT
cord-256444-grw5s2pf	188	15	other	other	JJ
cord-256444-grw5s2pf	188	16	being	be	VBG
cord-256444-grw5s2pf	188	17	the	the	DT
cord-256444-grw5s2pf	188	18	E	e	NN
cord-256444-grw5s2pf	188	19	protein	protein	NN
cord-256444-grw5s2pf	188	20	(	(	-LRB-
cord-256444-grw5s2pf	188	21	see	see	VB
cord-256444-grw5s2pf	188	22	below	below	RB
cord-256444-grw5s2pf	188	23	)	)	-RRB-
cord-256444-grw5s2pf	188	24	]	]	-RRB-
cord-256444-grw5s2pf	188	25	that	that	WDT
cord-256444-grw5s2pf	188	26	are	be	VBP
cord-256444-grw5s2pf	188	27	essential	essential	JJ
cord-256444-grw5s2pf	188	28	for	for	IN
cord-256444-grw5s2pf	188	29	the	the	DT
cord-256444-grw5s2pf	188	30	production	production	NN
cord-256444-grw5s2pf	188	31	of	of	IN
cord-256444-grw5s2pf	188	32	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	188	33	-	-	HYPH
cord-256444-grw5s2pf	188	34	like	like	JJ
cord-256444-grw5s2pf	188	35	particles	particle	NNS
cord-256444-grw5s2pf	188	36	.	.	.
cord-256444-grw5s2pf	189	1	The	the	DT
cord-256444-grw5s2pf	189	2	sequence	sequence	NN
cord-256444-grw5s2pf	189	3	of	of	IN
cord-256444-grw5s2pf	189	4	the	the	DT
cord-256444-grw5s2pf	189	5	M	M	NNP
cord-256444-grw5s2pf	189	6	protein	protein	NN
cord-256444-grw5s2pf	189	7	reveals	reveal	VBZ
cord-256444-grw5s2pf	189	8	that	that	IN
cord-256444-grw5s2pf	189	9	the	the	DT
cord-256444-grw5s2pf	189	10	M	M	NNP
cord-256444-grw5s2pf	189	11	polypeptides	polypeptide	NNS
cord-256444-grw5s2pf	189	12	comprise	comprise	VBP
cord-256444-grw5s2pf	189	13	225	225	CD
cord-256444-grw5s2pf	189	14	-	-	SYM
cord-256444-grw5s2pf	189	15	230	230	CD
cord-256444-grw5s2pf	189	16	amino	amino	JJ
cord-256444-grw5s2pf	189	17	acids	acid	NNS
cord-256444-grw5s2pf	189	18	,	,	,
cord-256444-grw5s2pf	189	19	except	except	IN
cord-256444-grw5s2pf	189	20	for	for	IN
cord-256444-grw5s2pf	189	21	some	some	DT
cord-256444-grw5s2pf	189	22	members	member	NNS
cord-256444-grw5s2pf	189	23	of	of	IN
cord-256444-grw5s2pf	189	24	the	the	DT
cord-256444-grw5s2pf	189	25	TGEV	TGEV	NNP
cord-256444-grw5s2pf	189	26	group	group	NN
cord-256444-grw5s2pf	189	27	,	,	,
cord-256444-grw5s2pf	189	28	which	which	WDT
cord-256444-grw5s2pf	189	29	have	have	VBP
cord-256444-grw5s2pf	189	30	an	an	DT
cord-256444-grw5s2pf	189	31	additional	additional	JJ
cord-256444-grw5s2pf	189	32	30	30	CD
cord-256444-grw5s2pf	189	33	or	or	CC
cord-256444-grw5s2pf	189	34	so	so	RB
cord-256444-grw5s2pf	189	35	residues	residue	VBZ
cord-256444-grw5s2pf	189	36	a	a	DT
cord-256444-grw5s2pf	189	37	t	t	NN
cord-256444-grw5s2pf	189	38	the	the	DT
cord-256444-grw5s2pf	189	39	amino	amino	NN
cord-256444-grw5s2pf	189	40	terminus	terminus	NN
cord-256444-grw5s2pf	189	41	,	,	,
cord-256444-grw5s2pf	189	42	forming	form	VBG
cord-256444-grw5s2pf	189	43	a	a	DT
cord-256444-grw5s2pf	189	44	cleavable	cleavable	JJ
cord-256444-grw5s2pf	189	45	membrane	membrane	NN
cord-256444-grw5s2pf	189	46	insertion	insertion	NN
cord-256444-grw5s2pf	189	47	signal	signal	NN
cord-256444-grw5s2pf	189	48	.	.	.
cord-256444-grw5s2pf	190	1	The	the	DT
cord-256444-grw5s2pf	190	2	amino	amino	NN
cord-256444-grw5s2pf	190	3	-	-	HYPH
cord-256444-grw5s2pf	190	4	terminal	terminal	NN
cord-256444-grw5s2pf	190	5	20	20	CD
cord-256444-grw5s2pf	190	6	or	or	CC
cord-256444-grw5s2pf	190	7	so	so	RB
cord-256444-grw5s2pf	190	8	residues	residue	NNS
cord-256444-grw5s2pf	190	9	of	of	IN
cord-256444-grw5s2pf	190	10	the	the	DT
cord-256444-grw5s2pf	190	11	mature	mature	JJ
cord-256444-grw5s2pf	190	12	M	M	NNP
cord-256444-grw5s2pf	190	13	protein	protein	NN
cord-256444-grw5s2pf	190	14	of	of	IN
cord-256444-grw5s2pf	190	15	all	all	PDT
cord-256444-grw5s2pf	190	16	the	the	DT
cord-256444-grw5s2pf	190	17	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	190	18	are	be	VBP
cord-256444-grw5s2pf	190	19	hydrophilic	hydrophilic	JJ
cord-256444-grw5s2pf	190	20	,	,	,
cord-256444-grw5s2pf	190	21	exposed	expose	VBN
cord-256444-grw5s2pf	190	22	at	at	IN
cord-256444-grw5s2pf	190	23	the	the	DT
cord-256444-grw5s2pf	190	24	virion	virion	NN
cord-256444-grw5s2pf	190	25	surface	surface	NN
cord-256444-grw5s2pf	190	26	,	,	,
cord-256444-grw5s2pf	190	27	and	and	CC
cord-256444-grw5s2pf	190	28	have	have	VBP
cord-256444-grw5s2pf	190	29	a	a	DT
cord-256444-grw5s2pf	190	30	small	small	JJ
cord-256444-grw5s2pf	190	31	number	number	NN
cord-256444-grw5s2pf	190	32	of	of	IN
cord-256444-grw5s2pf	190	33	glycosylation	glycosylation	NN
cord-256444-grw5s2pf	190	34	sites	site	NNS
cord-256444-grw5s2pf	190	35	.	.	.
cord-256444-grw5s2pf	191	1	Glycans	glycan	NNS
cord-256444-grw5s2pf	191	2	are	be	VBP
cord-256444-grw5s2pf	191	3	of	of	IN
cord-256444-grw5s2pf	191	4	the	the	DT
cord-256444-grw5s2pf	191	5	N	n	NN
cord-256444-grw5s2pf	191	6	-	-	HYPH
cord-256444-grw5s2pf	191	7	linked	link	VBN
cord-256444-grw5s2pf	191	8	type	type	NN
cord-256444-grw5s2pf	191	9	for	for	IN
cord-256444-grw5s2pf	191	10	IBV	IBV	NNP
cord-256444-grw5s2pf	191	11	and	and	CC
cord-256444-grw5s2pf	191	12	the	the	DT
cord-256444-grw5s2pf	191	13	TGEV	TGEV	NNP
cord-256444-grw5s2pf	191	14	group	group	NN
cord-256444-grw5s2pf	191	15	and	and	CC
cord-256444-grw5s2pf	191	16	O	o	NN
cord-256444-grw5s2pf	191	17	-	-	HYPH
cord-256444-grw5s2pf	191	18	linked	link	VBN
cord-256444-grw5s2pf	191	19	for	for	IN
cord-256444-grw5s2pf	191	20	the	the	DT
cord-256444-grw5s2pf	191	21	MHV	MHV	NNP
cord-256444-grw5s2pf	191	22	group	group	NN
cord-256444-grw5s2pf	191	23	(	(	-LRB-
cord-256444-grw5s2pf	191	24	Rottier	Rottier	NNP
cord-256444-grw5s2pf	191	25	,	,	,
cord-256444-grw5s2pf	191	26	1995	1995	CD
cord-256444-grw5s2pf	191	27	)	)	-RRB-
cord-256444-grw5s2pf	191	28	.	.	.
cord-256444-grw5s2pf	192	1	The	the	DT
cord-256444-grw5s2pf	192	2	remainder	remainder	NN
cord-256444-grw5s2pf	192	3	of	of	IN
cord-256444-grw5s2pf	192	4	the	the	DT
cord-256444-grw5s2pf	192	5	N	n	CD
cord-256444-grw5s2pf	192	6	-	-	HYPH
cord-256444-grw5s2pf	192	7	terminal	terminal	JJ
cord-256444-grw5s2pf	192	8	half	half	NN
cord-256444-grw5s2pf	192	9	of	of	IN
cord-256444-grw5s2pf	192	10	the	the	DT
cord-256444-grw5s2pf	192	11	molecule	molecule	NN
cord-256444-grw5s2pf	192	12	forms	form	VBZ
cord-256444-grw5s2pf	192	13	three	three	CD
cord-256444-grw5s2pf	192	14	helical	helical	JJ
cord-256444-grw5s2pf	192	15	membrane	membrane	NN
cord-256444-grw5s2pf	192	16	-	-	HYPH
cord-256444-grw5s2pf	192	17	spanning	span	VBG
cord-256444-grw5s2pf	192	18	domains	domain	NNS
cord-256444-grw5s2pf	192	19	,	,	,
cord-256444-grw5s2pf	192	20	although	although	IN
cord-256444-grw5s2pf	192	21	a	a	DT
cord-256444-grw5s2pf	192	22	mutant	mutant	JJ
cord-256444-grw5s2pf	192	23	M	M	NNP
cord-256444-grw5s2pf	192	24	protein	protein	NN
cord-256444-grw5s2pf	192	25	which	which	WDT
cord-256444-grw5s2pf	192	26	lacked	lack	VBD
cord-256444-grw5s2pf	192	27	all	all	DT
cord-256444-grw5s2pf	192	28	three	three	CD
cord-256444-grw5s2pf	192	29	of	of	IN
cord-256444-grw5s2pf	192	30	the	the	DT
cord-256444-grw5s2pf	192	31	membrane	membrane	NN
cord-256444-grw5s2pf	192	32	-	-	HYPH
cord-256444-grw5s2pf	192	33	spanning	span	VBG
cord-256444-grw5s2pf	192	34	domains	domain	NNS
cord-256444-grw5s2pf	192	35	did	do	VBD
cord-256444-grw5s2pf	192	36	associate	associate	VB
cord-256444-grw5s2pf	192	37	with	with	IN
cord-256444-grw5s2pf	192	38	membranes	membrane	NNS
cord-256444-grw5s2pf	192	39	in	in	IN
cord-256444-grw5s2pf	192	40	uitro	uitro	NNP
cord-256444-grw5s2pf	193	1	(	(	-LRB-
cord-256444-grw5s2pf	193	2	Mayer	Mayer	NNP
cord-256444-grw5s2pf	193	3	et	et	NNP
cord-256444-grw5s2pf	193	4	al	al	NNP
cord-256444-grw5s2pf	193	5	.	.	NNP
cord-256444-grw5s2pf	193	6	,	,	,
cord-256444-grw5s2pf	193	7	1988	1988	CD
cord-256444-grw5s2pf	193	8	)	)	-RRB-
cord-256444-grw5s2pf	193	9	.	.	.
cord-256444-grw5s2pf	194	1	The	the	DT
cord-256444-grw5s2pf	194	2	structure	structure	NN
cord-256444-grw5s2pf	194	3	of	of	IN
cord-256444-grw5s2pf	194	4	the	the	DT
cord-256444-grw5s2pf	194	5	C	C	NNP
cord-256444-grw5s2pf	194	6	-	-	HYPH
cord-256444-grw5s2pf	194	7	terminal	terminal	NN
cord-256444-grw5s2pf	194	8	half	half	NN
cord-256444-grw5s2pf	194	9	is	be	VBZ
cord-256444-grw5s2pf	194	10	uncertain	uncertain	JJ
cord-256444-grw5s2pf	194	11	,	,	,
cord-256444-grw5s2pf	194	12	but	but	CC
cord-256444-grw5s2pf	194	13	it	-PRON-	PRP
cord-256444-grw5s2pf	194	14	is	be	VBZ
cord-256444-grw5s2pf	194	15	believed	believe	VBN
cord-256444-grw5s2pf	194	16	to	to	TO
cord-256444-grw5s2pf	194	17	be	be	VB
cord-256444-grw5s2pf	194	18	largely	largely	RB
cord-256444-grw5s2pf	194	19	situated	situate	VBN
cord-256444-grw5s2pf	194	20	on	on	IN
cord-256444-grw5s2pf	194	21	the	the	DT
cord-256444-grw5s2pf	194	22	inside	inside	NN
cord-256444-grw5s2pf	194	23	of	of	IN
cord-256444-grw5s2pf	194	24	the	the	DT
cord-256444-grw5s2pf	194	25	viral	viral	JJ
cord-256444-grw5s2pf	194	26	envelope	envelope	NN
cord-256444-grw5s2pf	194	27	,	,	,
cord-256444-grw5s2pf	194	28	based	base	VBN
cord-256444-grw5s2pf	194	29	on	on	IN
cord-256444-grw5s2pf	194	30	protease	protease	NN
cord-256444-grw5s2pf	194	31	susceptibility	susceptibility	NN
cord-256444-grw5s2pf	194	32	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	194	33	et	et	NNP
cord-256444-grw5s2pf	194	34	al	al	NNP
cord-256444-grw5s2pf	194	35	.	.	NNP
cord-256444-grw5s2pf	194	36	,	,	,
cord-256444-grw5s2pf	194	37	1986b	1986b	CD
cord-256444-grw5s2pf	194	38	)	)	-RRB-
cord-256444-grw5s2pf	194	39	and	and	CC
cord-256444-grw5s2pf	194	40	sequence	sequence	NN
cord-256444-grw5s2pf	194	41	-	-	HYPH
cord-256444-grw5s2pf	194	42	based	base	VBN
cord-256444-grw5s2pf	194	43	predictions	prediction	NNS
cord-256444-grw5s2pf	194	44	(	(	-LRB-
cord-256444-grw5s2pf	194	45	Armstronget	Armstronget	NNP
cord-256444-grw5s2pf	194	46	al	al	NNP
cord-256444-grw5s2pf	194	47	.	.	.
cord-256444-grw5s2pf	195	1	,	,	,
cord-256444-grw5s2pf	195	2	1984	1984	CD
cord-256444-grw5s2pf	195	3	;	;	:
cord-256444-grw5s2pf	195	4	Rottier	Rottier	NNP
cord-256444-grw5s2pf	195	5	et	et	NNP
cord-256444-grw5s2pf	195	6	al	al	NNP
cord-256444-grw5s2pf	195	7	.	.	NNP
cord-256444-grw5s2pf	195	8	,	,	,
cord-256444-grw5s2pf	195	9	1986	1986	CD
cord-256444-grw5s2pf	195	10	)	)	-RRB-
cord-256444-grw5s2pf	195	11	.	.	.
cord-256444-grw5s2pf	196	1	However	however	RB
cord-256444-grw5s2pf	196	2	,	,	,
cord-256444-grw5s2pf	196	3	some	some	DT
cord-256444-grw5s2pf	196	4	M	M	NNP
cord-256444-grw5s2pf	196	5	molecules	molecule	NNS
cord-256444-grw5s2pf	196	6	of	of	IN
cord-256444-grw5s2pf	196	7	TGEV	TGEV	NNP
cord-256444-grw5s2pf	196	8	virions	virion	NNS
cord-256444-grw5s2pf	196	9	have	have	VBP
cord-256444-grw5s2pf	196	10	the	the	DT
cord-256444-grw5s2pf	196	11	C	C	NNP
cord-256444-grw5s2pf	196	12	terminus	terminus	NN
cord-256444-grw5s2pf	196	13	exposed	expose	VBD
cord-256444-grw5s2pf	196	14	a	a	DT
cord-256444-grw5s2pf	196	15	t	t	NN
cord-256444-grw5s2pf	196	16	the	the	DT
cord-256444-grw5s2pf	196	17	virion	virion	NN
cord-256444-grw5s2pf	196	18	surface	surface	NN
cord-256444-grw5s2pf	197	1	(	(	-LRB-
cord-256444-grw5s2pf	197	2	Laviada	Laviada	NNP
cord-256444-grw5s2pf	197	3	et	et	NNP
cord-256444-grw5s2pf	197	4	al	al	NNP
cord-256444-grw5s2pf	197	5	.	.	NNP
cord-256444-grw5s2pf	197	6	,	,	,
cord-256444-grw5s2pf	197	7	1990	1990	CD
cord-256444-grw5s2pf	197	8	;	;	:
cord-256444-grw5s2pf	197	9	Risco	Risco	NNP
cord-256444-grw5s2pf	197	10	et	et	NNP
cord-256444-grw5s2pf	197	11	al	al	NNP
cord-256444-grw5s2pf	197	12	.	.	NNP
cord-256444-grw5s2pf	197	13	,	,	,
cord-256444-grw5s2pf	197	14	1995	1995	CD
cord-256444-grw5s2pf	197	15	)	)	-RRB-
cord-256444-grw5s2pf	197	16	.	.	.
cord-256444-grw5s2pf	198	1	Moreover	moreover	RB
cord-256444-grw5s2pf	198	2	,	,	,
cord-256444-grw5s2pf	198	3	MAb	MAb	NNS
cord-256444-grw5s2pf	198	4	specific	specific	JJ
cord-256444-grw5s2pf	198	5	for	for	IN
cord-256444-grw5s2pf	198	6	the	the	DT
cord-256444-grw5s2pf	198	7	C	C	NNP
cord-256444-grw5s2pf	198	8	-	-	HYPH
cord-256444-grw5s2pf	198	9	terminal46	terminal46	NNS
cord-256444-grw5s2pf	198	10	amino	amino	NNS
cord-256444-grw5s2pf	198	11	acids	acid	NNS
cord-256444-grw5s2pf	198	12	of	of	IN
cord-256444-grw5s2pf	198	13	M	M	NNP
cord-256444-grw5s2pf	198	14	neutralized	neutralize	VBD
cord-256444-grw5s2pf	198	15	TGEV	TGEV	NNP
cord-256444-grw5s2pf	198	16	virions	virion	NNS
cord-256444-grw5s2pf	198	17	in	in	IN
cord-256444-grw5s2pf	198	18	the	the	DT
cord-256444-grw5s2pf	198	19	presence	presence	NN
cord-256444-grw5s2pf	198	20	of	of	IN
cord-256444-grw5s2pf	198	21	complement	complement	NN
cord-256444-grw5s2pf	198	22	and	and	CC
cord-256444-grw5s2pf	198	23	caused	cause	VBD
cord-256444-grw5s2pf	198	24	antibody	antibody	NN
cord-256444-grw5s2pf	198	25	-	-	HYPH
cord-256444-grw5s2pf	198	26	mediated	mediate	VBN
cord-256444-grw5s2pf	198	27	,	,	,
cord-256444-grw5s2pf	198	28	complementdependent	complementdependent	JJ
cord-256444-grw5s2pf	198	29	cytolysis	cytolysis	NN
cord-256444-grw5s2pf	198	30	of	of	IN
cord-256444-grw5s2pf	198	31	TGEV	TGEV	NNP
cord-256444-grw5s2pf	198	32	-	-	HYPH
cord-256444-grw5s2pf	198	33	infected	infect	VBN
cord-256444-grw5s2pf	198	34	cells	cell	NNS
cord-256444-grw5s2pf	199	1	(	(	-LRB-
cord-256444-grw5s2pf	199	2	Risco	Risco	NNP
cord-256444-grw5s2pf	199	3	et	et	NNP
cord-256444-grw5s2pf	199	4	al	al	NNP
cord-256444-grw5s2pf	199	5	.	.	NNP
cord-256444-grw5s2pf	199	6	,	,	,
cord-256444-grw5s2pf	199	7	1995	1995	CD
cord-256444-grw5s2pf	199	8	)	)	-RRB-
cord-256444-grw5s2pf	199	9	.	.	.
cord-256444-grw5s2pf	200	1	Studies	study	NNS
cord-256444-grw5s2pf	200	2	with	with	IN
cord-256444-grw5s2pf	200	3	mutant	mutant	JJ
cord-256444-grw5s2pf	200	4	MHV	MHV	NNP
cord-256444-grw5s2pf	200	5	M	M	NNP
cord-256444-grw5s2pf	200	6	proteins	protein	NNS
cord-256444-grw5s2pf	200	7	expressed	express	VBN
cord-256444-grw5s2pf	200	8	from	from	IN
cord-256444-grw5s2pf	200	9	vaccinia	vaccinia	NN
cord-256444-grw5s2pf	200	10	virus	virus	NN
cord-256444-grw5s2pf	200	11	recombinants	recombinant	NNS
cord-256444-grw5s2pf	200	12	had	have	VBD
cord-256444-grw5s2pf	200	13	shown	show	VBN
cord-256444-grw5s2pf	200	14	that	that	IN
cord-256444-grw5s2pf	200	15	some	some	DT
cord-256444-grw5s2pf	200	16	had	have	VBD
cord-256444-grw5s2pf	200	17	the	the	DT
cord-256444-grw5s2pf	200	18	N	n	CD
cord-256444-grw5s2pf	200	19	terminus	terminus	NN
cord-256444-grw5s2pf	200	20	and	and	CC
cord-256444-grw5s2pf	200	21	others	other	NNS
cord-256444-grw5s2pf	200	22	the	the	DT
cord-256444-grw5s2pf	200	23	C	C	NNP
cord-256444-grw5s2pf	200	24	terminus	terminus	NN
cord-256444-grw5s2pf	201	1	a	a	DT
cord-256444-grw5s2pf	201	2	t	t	NN
cord-256444-grw5s2pf	201	3	the	the	DT
cord-256444-grw5s2pf	201	4	luminal	luminal	JJ
cord-256444-grw5s2pf	201	5	side	side	NN
cord-256444-grw5s2pf	201	6	of	of	IN
cord-256444-grw5s2pf	201	7	the	the	DT
cord-256444-grw5s2pf	201	8	endoplasmic	endoplasmic	NN
cord-256444-grw5s2pf	201	9	reticulum	reticulum	NN
cord-256444-grw5s2pf	201	10	,	,	,
cord-256444-grw5s2pf	201	11	equivalent	equivalent	JJ
cord-256444-grw5s2pf	201	12	to	to	IN
cord-256444-grw5s2pf	201	13	the	the	DT
cord-256444-grw5s2pf	201	14	outer	outer	JJ
cord-256444-grw5s2pf	201	15	surface	surface	NN
cord-256444-grw5s2pf	201	16	of	of	IN
cord-256444-grw5s2pf	201	17	virions	virion	NNS
cord-256444-grw5s2pf	201	18	(	(	-LRB-
cord-256444-grw5s2pf	201	19	Locker	Locker	NNP
cord-256444-grw5s2pf	201	20	et	et	FW
cord-256444-grw5s2pf	201	21	al	al	NNP
cord-256444-grw5s2pf	201	22	.	.	NNP
cord-256444-grw5s2pf	201	23	,	,	,
cord-256444-grw5s2pf	201	24	199213	199213	CD
cord-256444-grw5s2pf	201	25	)	)	-RRB-
cord-256444-grw5s2pf	201	26	.	.	.
cord-256444-grw5s2pf	202	1	Some	some	DT
cord-256444-grw5s2pf	202	2	molecules	molecule	NNS
cord-256444-grw5s2pf	202	3	of	of	IN
cord-256444-grw5s2pf	202	4	one	one	CD
cord-256444-grw5s2pf	202	5	mutant	mutant	JJ
cord-256444-grw5s2pf	202	6	M	M	NNP
cord-256444-grw5s2pf	202	7	protein	protein	NN
cord-256444-grw5s2pf	202	8	had	have	VBD
cord-256444-grw5s2pf	202	9	both	both	DT
cord-256444-grw5s2pf	202	10	termini	terminus	NNS
cord-256444-grw5s2pf	202	11	at	at	IN
cord-256444-grw5s2pf	202	12	the	the	DT
cord-256444-grw5s2pf	202	13	luminal	luminal	JJ
cord-256444-grw5s2pf	202	14	surface	surface	NN
cord-256444-grw5s2pf	202	15	,	,	,
cord-256444-grw5s2pf	202	16	and	and	CC
cord-256444-grw5s2pf	202	17	other	other	JJ
cord-256444-grw5s2pf	202	18	molecules	molecule	NNS
cord-256444-grw5s2pf	202	19	had	have	VBD
cord-256444-grw5s2pf	202	20	both	both	DT
cord-256444-grw5s2pf	202	21	termini	terminus	NNS
cord-256444-grw5s2pf	202	22	at	at	IN
cord-256444-grw5s2pf	202	23	the	the	DT
cord-256444-grw5s2pf	202	24	cytoplasmic	cytoplasmic	JJ
cord-256444-grw5s2pf	202	25	surface	surface	NN
cord-256444-grw5s2pf	202	26	(	(	-LRB-
cord-256444-grw5s2pf	202	27	Locker	locker	NN
cord-256444-grw5s2pf	202	28	et	et	FW
cord-256444-grw5s2pf	202	29	al	al	NNP
cord-256444-grw5s2pf	202	30	.	.	NNP
cord-256444-grw5s2pf	202	31	,	,	,
cord-256444-grw5s2pf	202	32	199213	199213	CD
cord-256444-grw5s2pf	202	33	,	,	,
cord-256444-grw5s2pf	202	34	1994	1994	CD
cord-256444-grw5s2pf	202	35	)	)	-RRB-
cord-256444-grw5s2pf	202	36	.	.	.
cord-256444-grw5s2pf	203	1	Thus	thus	RB
cord-256444-grw5s2pf	203	2	,	,	,
cord-256444-grw5s2pf	203	3	the	the	DT
cord-256444-grw5s2pf	203	4	precise	precise	JJ
cord-256444-grw5s2pf	203	5	topology	topology	NN
cord-256444-grw5s2pf	203	6	and	and	CC
cord-256444-grw5s2pf	203	7	the	the	DT
cord-256444-grw5s2pf	203	8	structural	structural	JJ
cord-256444-grw5s2pf	203	9	role	role	NN
cord-256444-grw5s2pf	203	10	of	of	IN
cord-256444-grw5s2pf	203	11	the	the	DT
cord-256444-grw5s2pf	203	12	M	M	NNP
cord-256444-grw5s2pf	203	13	protein	protein	NN
cord-256444-grw5s2pf	203	14	are	be	VBP
cord-256444-grw5s2pf	203	15	still	still	RB
cord-256444-grw5s2pf	203	16	not	not	RB
cord-256444-grw5s2pf	203	17	certain	certain	JJ
cord-256444-grw5s2pf	203	18	.	.	.
cord-256444-grw5s2pf	204	1	Recent	recent	JJ
cord-256444-grw5s2pf	204	2	studies	study	NNS
cord-256444-grw5s2pf	204	3	have	have	VBP
cord-256444-grw5s2pf	204	4	shown	show	VBN
cord-256444-grw5s2pf	204	5	that	that	IN
cord-256444-grw5s2pf	204	6	some	some	DT
cord-256444-grw5s2pf	204	7	M	M	NNP
cord-256444-grw5s2pf	204	8	proteins	protein	NNS
cord-256444-grw5s2pf	204	9	are	be	VBP
cord-256444-grw5s2pf	204	10	also	also	RB
cord-256444-grw5s2pf	204	11	associated	associate	VBN
cord-256444-grw5s2pf	204	12	with	with	IN
cord-256444-grw5s2pf	204	13	the	the	DT
cord-256444-grw5s2pf	204	14	RNP	RNP	NNP
cord-256444-grw5s2pf	204	15	core	core	NN
cord-256444-grw5s2pf	204	16	of	of	IN
cord-256444-grw5s2pf	204	17	TGEV	TGEV	NNP
cord-256444-grw5s2pf	204	18	and	and	CC
cord-256444-grw5s2pf	204	19	constitute	constitute	VBP
cord-256444-grw5s2pf	204	20	the	the	DT
cord-256444-grw5s2pf	204	21	outer	outer	JJ
cord-256444-grw5s2pf	204	22	shell	shell	NN
cord-256444-grw5s2pf	204	23	of	of	IN
cord-256444-grw5s2pf	204	24	the	the	DT
cord-256444-grw5s2pf	204	25	internal	internal	JJ
cord-256444-grw5s2pf	204	26	core	core	NN
cord-256444-grw5s2pf	205	1	(	(	-LRB-
cord-256444-grw5s2pf	205	2	Risco	Risco	NNP
cord-256444-grw5s2pf	205	3	et	et	NNP
cord-256444-grw5s2pf	205	4	al	al	NNP
cord-256444-grw5s2pf	205	5	.	.	NNP
cord-256444-grw5s2pf	205	6	,	,	,
cord-256444-grw5s2pf	205	7	1996	1996	CD
cord-256444-grw5s2pf	205	8	)	)	-RRB-
cord-256444-grw5s2pf	205	9	.	.	.
cord-256444-grw5s2pf	206	1	This	this	DT
cord-256444-grw5s2pf	206	2	core	core	NN
cord-256444-grw5s2pf	206	3	-	-	HYPH
cord-256444-grw5s2pf	206	4	associated	associated	JJ
cord-256444-grw5s2pf	206	5	M	M	NNP
cord-256444-grw5s2pf	206	6	can	can	MD
cord-256444-grw5s2pf	206	7	be	be	VB
cord-256444-grw5s2pf	206	8	clearly	clearly	RB
cord-256444-grw5s2pf	206	9	separated	separate	VBN
cord-256444-grw5s2pf	206	10	from	from	IN
cord-256444-grw5s2pf	206	11	the	the	DT
cord-256444-grw5s2pf	206	12	viral	viral	JJ
cord-256444-grw5s2pf	206	13	envelope	envelope	NN
cord-256444-grw5s2pf	206	14	.	.	.
cord-256444-grw5s2pf	207	1	Therefore	therefore	RB
cord-256444-grw5s2pf	207	2	,	,	,
cord-256444-grw5s2pf	207	3	M	M	NNP
cord-256444-grw5s2pf	207	4	may	may	MD
cord-256444-grw5s2pf	207	5	play	play	VB
cord-256444-grw5s2pf	207	6	a	a	DT
cord-256444-grw5s2pf	207	7	dual	dual	JJ
cord-256444-grw5s2pf	207	8	structural	structural	JJ
cord-256444-grw5s2pf	207	9	role	role	NN
cord-256444-grw5s2pf	207	10	in	in	IN
cord-256444-grw5s2pf	207	11	forming	form	VBG
cord-256444-grw5s2pf	207	12	both	both	CC
cord-256444-grw5s2pf	207	13	the	the	DT
cord-256444-grw5s2pf	207	14	envelope	envelope	NN
cord-256444-grw5s2pf	207	15	and	and	CC
cord-256444-grw5s2pf	207	16	the	the	DT
cord-256444-grw5s2pf	207	17	internal	internal	JJ
cord-256444-grw5s2pf	207	18	core	core	NN
cord-256444-grw5s2pf	207	19	of	of	IN
cord-256444-grw5s2pf	207	20	the	the	DT
cord-256444-grw5s2pf	207	21	virion	virion	NN
cord-256444-grw5s2pf	207	22	.	.	.
cord-256444-grw5s2pf	208	1	Several	several	JJ
cord-256444-grw5s2pf	208	2	properties	property	NNS
cord-256444-grw5s2pf	208	3	of	of	IN
cord-256444-grw5s2pf	208	4	the	the	DT
cord-256444-grw5s2pf	208	5	M	M	NNP
cord-256444-grw5s2pf	208	6	protein	protein	NN
cord-256444-grw5s2pf	208	7	suggest	suggest	VBP
cord-256444-grw5s2pf	208	8	that	that	IN
cord-256444-grw5s2pf	208	9	it	-PRON-	PRP
cord-256444-grw5s2pf	208	10	is	be	VBZ
cord-256444-grw5s2pf	208	11	involved	involve	VBN
cord-256444-grw5s2pf	208	12	in	in	IN
cord-256444-grw5s2pf	208	13	virus	virus	NN
cord-256444-grw5s2pf	208	14	particle	particle	NN
cord-256444-grw5s2pf	208	15	assembly	assembly	NN
cord-256444-grw5s2pf	208	16	:	:	:
cord-256444-grw5s2pf	208	17	(	(	-LRB-
cord-256444-grw5s2pf	208	18	1	1	LS
cord-256444-grw5s2pf	208	19	)	)	-RRB-
cord-256444-grw5s2pf	209	1	The	the	DT
cord-256444-grw5s2pf	209	2	M	M	NNP
cord-256444-grw5s2pf	209	3	protein	protein	NN
cord-256444-grw5s2pf	209	4	binds	bind	VBZ
cord-256444-grw5s2pf	209	5	to	to	IN
cord-256444-grw5s2pf	209	6	the	the	DT
cord-256444-grw5s2pf	209	7	purified	purify	VBN
cord-256444-grw5s2pf	209	8	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	209	9	in	in	IN
cord-256444-grw5s2pf	209	10	uitro	uitro	NNP
cord-256444-grw5s2pf	209	11	(	(	-LRB-
cord-256444-grw5s2pf	209	12	Sturman	Sturman	NNP
cord-256444-grw5s2pf	209	13	et	et	NNP
cord-256444-grw5s2pf	209	14	al	al	NNP
cord-256444-grw5s2pf	209	15	.	.	NNP
cord-256444-grw5s2pf	209	16	,	,	,
cord-256444-grw5s2pf	209	17	1980	1980	CD
cord-256444-grw5s2pf	209	18	)	)	-RRB-
cord-256444-grw5s2pf	209	19	.	.	.
cord-256444-grw5s2pf	210	1	(	(	-LRB-
cord-256444-grw5s2pf	210	2	2	2	LS
cord-256444-grw5s2pf	210	3	)	)	-RRB-
cord-256444-grw5s2pf	210	4	When	when	WRB
cord-256444-grw5s2pf	210	5	the	the	DT
cord-256444-grw5s2pf	210	6	M	M	NNP
cord-256444-grw5s2pf	210	7	protein	protein	NN
cord-256444-grw5s2pf	210	8	was	be	VBD
cord-256444-grw5s2pf	210	9	expressed	express	VBN
cord-256444-grw5s2pf	210	10	alone	alone	JJ
cord-256444-grw5s2pf	210	11	,	,	,
cord-256444-grw5s2pf	210	12	it	-PRON-	PRP
cord-256444-grw5s2pf	210	13	was	be	VBD
cord-256444-grw5s2pf	210	14	localized	localize	VBN
cord-256444-grw5s2pf	210	15	in	in	IN
cord-256444-grw5s2pf	210	16	the	the	DT
cord-256444-grw5s2pf	210	17	Golgi	Golgi	NNP
cord-256444-grw5s2pf	210	18	complex	complex	NN
cord-256444-grw5s2pf	210	19	,	,	,
cord-256444-grw5s2pf	210	20	near	near	IN
cord-256444-grw5s2pf	210	21	the	the	DT
cord-256444-grw5s2pf	210	22	location	location	NN
cord-256444-grw5s2pf	210	23	where	where	WRB
cord-256444-grw5s2pf	210	24	virus	virus	NN
cord-256444-grw5s2pf	210	25	particles	particle	NNS
cord-256444-grw5s2pf	210	26	bud	bud	NN
cord-256444-grw5s2pf	210	27	(	(	-LRB-
cord-256444-grw5s2pf	210	28	Tooze	Tooze	NNP
cord-256444-grw5s2pf	210	29	et	et	NNP
cord-256444-grw5s2pf	210	30	al	al	NNP
cord-256444-grw5s2pf	210	31	.	.	NNP
cord-256444-grw5s2pf	210	32	,	,	,
cord-256444-grw5s2pf	210	33	1984	1984	CD
cord-256444-grw5s2pf	210	34	;	;	:
cord-256444-grw5s2pf	210	35	Tooze	Tooze	NNP
cord-256444-grw5s2pf	210	36	and	and	CC
cord-256444-grw5s2pf	210	37	Tooze	Tooze	NNP
cord-256444-grw5s2pf	210	38	,	,	,
cord-256444-grw5s2pf	210	39	1985	1985	CD
cord-256444-grw5s2pf	210	40	)	)	-RRB-
cord-256444-grw5s2pf	210	41	.	.	.
cord-256444-grw5s2pf	211	1	However	however	RB
cord-256444-grw5s2pf	211	2	,	,	,
cord-256444-grw5s2pf	211	3	recent	recent	JJ
cord-256444-grw5s2pf	211	4	studies	study	NNS
cord-256444-grw5s2pf	211	5	showed	show	VBD
cord-256444-grw5s2pf	211	6	that	that	IN
cord-256444-grw5s2pf	211	7	the	the	DT
cord-256444-grw5s2pf	211	8	site	site	NN
cord-256444-grw5s2pf	211	9	of	of	IN
cord-256444-grw5s2pf	211	10	M	M	NNP
cord-256444-grw5s2pf	211	11	protein	protein	NN
cord-256444-grw5s2pf	211	12	retention	retention	NN
cord-256444-grw5s2pf	211	13	in	in	IN
cord-256444-grw5s2pf	211	14	the	the	DT
cord-256444-grw5s2pf	211	15	Golgi	Golgi	NNP
cord-256444-grw5s2pf	211	16	was	be	VBD
cord-256444-grw5s2pf	211	17	slightly	slightly	RB
cord-256444-grw5s2pf	211	18	different	different	JJ
cord-256444-grw5s2pf	211	19	from	from	IN
cord-256444-grw5s2pf	211	20	that	that	DT
cord-256444-grw5s2pf	211	21	for	for	IN
cord-256444-grw5s2pf	211	22	viral	viral	JJ
cord-256444-grw5s2pf	211	23	particle	particle	NN
cord-256444-grw5s2pf	211	24	budding	bud	VBG
cord-256444-grw5s2pf	211	25	(	(	-LRB-
cord-256444-grw5s2pf	211	26	Klumperman	Klumperman	NNP
cord-256444-grw5s2pf	211	27	et	et	FW
cord-256444-grw5s2pf	211	28	al	al	NNP
cord-256444-grw5s2pf	211	29	.	.	NNP
cord-256444-grw5s2pf	211	30	,	,	,
cord-256444-grw5s2pf	211	31	19941	19941	CD
cord-256444-grw5s2pf	211	32	,	,	,
cord-256444-grw5s2pf	211	33	suggesting	suggest	VBG
cord-256444-grw5s2pf	211	34	that	that	IN
cord-256444-grw5s2pf	211	35	additional	additional	JJ
cord-256444-grw5s2pf	211	36	factors	factor	NNS
cord-256444-grw5s2pf	211	37	are	be	VBP
cord-256444-grw5s2pf	211	38	involved	involve	VBN
cord-256444-grw5s2pf	211	39	in	in	IN
cord-256444-grw5s2pf	211	40	virus	virus	NN
cord-256444-grw5s2pf	211	41	particle	particle	NN
cord-256444-grw5s2pf	211	42	assembly	assembly	NN
cord-256444-grw5s2pf	211	43	.	.	.
cord-256444-grw5s2pf	212	1	This	this	DT
cord-256444-grw5s2pf	212	2	will	will	MD
cord-256444-grw5s2pf	212	3	be	be	VB
cord-256444-grw5s2pf	212	4	discussed	discuss	VBN
cord-256444-grw5s2pf	212	5	in	in	IN
cord-256444-grw5s2pf	212	6	Section	section	NN
cord-256444-grw5s2pf	212	7	V	v	NN
cord-256444-grw5s2pf	212	8	,	,	,
cord-256444-grw5s2pf	212	9	H	H	NNP
cord-256444-grw5s2pf	212	10	on	on	IN
cord-256444-grw5s2pf	212	11	virus	virus	NN
cord-256444-grw5s2pf	212	12	assembly	assembly	NN
cord-256444-grw5s2pf	212	13	.	.	.
cord-256444-grw5s2pf	213	1	The	the	DT
cord-256444-grw5s2pf	213	2	M	M	NNP
cord-256444-grw5s2pf	213	3	protein	protein	NN
cord-256444-grw5s2pf	213	4	of	of	IN
cord-256444-grw5s2pf	213	5	TGEV	TGEV	NNP
cord-256444-grw5s2pf	213	6	has	have	VBZ
cord-256444-grw5s2pf	213	7	a	a	DT
cord-256444-grw5s2pf	213	8	n	n	RB
cord-256444-grw5s2pf	213	9	additional	additional	JJ
cord-256444-grw5s2pf	213	10	biological	biological	JJ
cord-256444-grw5s2pf	213	11	activity	activity	NN
cord-256444-grw5s2pf	213	12	:	:	:
cord-256444-grw5s2pf	213	13	induction	induction	NN
cord-256444-grw5s2pf	213	14	of	of	IN
cord-256444-grw5s2pf	213	15	a	a	DT
cord-256444-grw5s2pf	213	16	-	-	HYPH
cord-256444-grw5s2pf	213	17	interferon	interferon	NN
cord-256444-grw5s2pf	213	18	(	(	-LRB-
cord-256444-grw5s2pf	213	19	Charley	Charley	NNP
cord-256444-grw5s2pf	213	20	and	and	CC
cord-256444-grw5s2pf	213	21	Laude	Laude	NNP
cord-256444-grw5s2pf	213	22	,	,	,
cord-256444-grw5s2pf	213	23	1988	1988	CD
cord-256444-grw5s2pf	213	24	;	;	:
cord-256444-grw5s2pf	213	25	Laude	Laude	NNP
cord-256444-grw5s2pf	213	26	et	et	NNP
cord-256444-grw5s2pf	213	27	al	al	NNP
cord-256444-grw5s2pf	213	28	.	.	NNP
cord-256444-grw5s2pf	213	29	,	,	,
cord-256444-grw5s2pf	213	30	1992	1992	CD
cord-256444-grw5s2pf	213	31	)	)	-RRB-
cord-256444-grw5s2pf	213	32	.	.	.
cord-256444-grw5s2pf	214	1	Thus	thus	RB
cord-256444-grw5s2pf	214	2	,	,	,
cord-256444-grw5s2pf	214	3	it	-PRON-	PRP
cord-256444-grw5s2pf	214	4	may	may	MD
cord-256444-grw5s2pf	214	5	play	play	VB
cord-256444-grw5s2pf	214	6	a	a	DT
cord-256444-grw5s2pf	214	7	role	role	NN
cord-256444-grw5s2pf	214	8	in	in	IN
cord-256444-grw5s2pf	214	9	viral	viral	JJ
cord-256444-grw5s2pf	214	10	pathogenesis	pathogenesis	NN
cord-256444-grw5s2pf	214	11	.	.	.
cord-256444-grw5s2pf	215	1	Monoclonal	monoclonal	JJ
cord-256444-grw5s2pf	215	2	antibodies	antibody	NNS
cord-256444-grw5s2pf	215	3	against	against	IN
cord-256444-grw5s2pf	215	4	the	the	DT
cord-256444-grw5s2pf	215	5	M	M	NNP
cord-256444-grw5s2pf	215	6	protein	protein	NN
cord-256444-grw5s2pf	215	7	do	do	VBP
cord-256444-grw5s2pf	215	8	not	not	RB
cord-256444-grw5s2pf	215	9	neutralize	neutralize	VB
cord-256444-grw5s2pf	215	10	viral	viral	JJ
cord-256444-grw5s2pf	215	11	infectivity	infectivity	NN
cord-256444-grw5s2pf	215	12	,	,	,
cord-256444-grw5s2pf	215	13	suggesting	suggest	VBG
cord-256444-grw5s2pf	215	14	that	that	IN
cord-256444-grw5s2pf	215	15	M	M	NNP
cord-256444-grw5s2pf	215	16	is	be	VBZ
cord-256444-grw5s2pf	215	17	not	not	RB
cord-256444-grw5s2pf	215	18	involved	involve	VBN
cord-256444-grw5s2pf	215	19	in	in	IN
cord-256444-grw5s2pf	215	20	receptor	receptor	NN
cord-256444-grw5s2pf	215	21	binding	binding	NN
cord-256444-grw5s2pf	215	22	.	.	.
cord-256444-grw5s2pf	216	1	However	however	RB
cord-256444-grw5s2pf	216	2	,	,	,
cord-256444-grw5s2pf	216	3	some	some	DT
cord-256444-grw5s2pf	216	4	of	of	IN
cord-256444-grw5s2pf	216	5	these	these	DT
cord-256444-grw5s2pf	216	6	antibodies	antibody	NNS
cord-256444-grw5s2pf	216	7	can	can	MD
cord-256444-grw5s2pf	216	8	neutralize	neutralize	VB
cord-256444-grw5s2pf	216	9	viral	viral	JJ
cord-256444-grw5s2pf	216	10	infectivity	infectivity	NN
cord-256444-grw5s2pf	216	11	in	in	IN
cord-256444-grw5s2pf	216	12	the	the	DT
cord-256444-grw5s2pf	216	13	presence	presence	NN
cord-256444-grw5s2pf	216	14	of	of	IN
cord-256444-grw5s2pf	216	15	complement	complement	NN
cord-256444-grw5s2pf	216	16	(	(	-LRB-
cord-256444-grw5s2pf	216	17	Collins	Collins	NNP
cord-256444-grw5s2pf	216	18	et	et	NNP
cord-256444-grw5s2pf	216	19	al	al	NNP
cord-256444-grw5s2pf	216	20	.	.	NNP
cord-256444-grw5s2pf	216	21	,	,	,
cord-256444-grw5s2pf	216	22	1982	1982	CD
cord-256444-grw5s2pf	216	23	;	;	:
cord-256444-grw5s2pf	216	24	Laviada	Laviada	NNP
cord-256444-grw5s2pf	216	25	et	et	NNP
cord-256444-grw5s2pf	216	26	al	al	NNP
cord-256444-grw5s2pf	216	27	.	.	NNP
cord-256444-grw5s2pf	216	28	,	,	,
cord-256444-grw5s2pf	216	29	1990	1990	CD
cord-256444-grw5s2pf	216	30	)	)	-RRB-
cord-256444-grw5s2pf	216	31	,	,	,
cord-256444-grw5s2pf	216	32	indicating	indicate	VBG
cord-256444-grw5s2pf	216	33	that	that	IN
cord-256444-grw5s2pf	216	34	part	part	NN
cord-256444-grw5s2pf	216	35	of	of	IN
cord-256444-grw5s2pf	216	36	the	the	DT
cord-256444-grw5s2pf	216	37	M	M	NNP
cord-256444-grw5s2pf	216	38	protein	protein	NN
cord-256444-grw5s2pf	216	39	is	be	VBZ
cord-256444-grw5s2pf	216	40	exposed	expose	VBN
cord-256444-grw5s2pf	216	41	on	on	IN
cord-256444-grw5s2pf	216	42	the	the	DT
cord-256444-grw5s2pf	216	43	virion	virion	NN
cord-256444-grw5s2pf	216	44	surface	surface	NN
cord-256444-grw5s2pf	216	45	.	.	.
cord-256444-grw5s2pf	217	1	The	the	DT
cord-256444-grw5s2pf	217	2	HE	HE	NNP
cord-256444-grw5s2pf	217	3	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	217	4	-	-	:
cord-256444-grw5s2pf	217	5	or	or	CC
cord-256444-grw5s2pf	217	6	perhaps	perhaps	RB
cord-256444-grw5s2pf	217	7	one	one	PRP
cord-256444-grw5s2pf	217	8	should	should	MD
cord-256444-grw5s2pf	217	9	say	say	VB
cord-256444-grw5s2pf	217	10	the	the	DT
cord-256444-grw5s2pf	217	11	HE	HE	NNP
cord-256444-grw5s2pf	217	12	gene	gene	NN
cord-256444-grw5s2pf	217	13	-	-	HYPH
cord-256444-grw5s2pf	217	14	of	of	IN
cord-256444-grw5s2pf	217	15	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	217	16	is	be	VBZ
cord-256444-grw5s2pf	217	17	something	something	NN
cord-256444-grw5s2pf	217	18	of	of	IN
cord-256444-grw5s2pf	217	19	a	a	DT
cord-256444-grw5s2pf	217	20	n	n	CD
cord-256444-grw5s2pf	217	21	enigma	enigma	NN
cord-256444-grw5s2pf	217	22	.	.	.
cord-256444-grw5s2pf	218	1	Only	only	RB
cord-256444-grw5s2pf	218	2	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	218	3	belonging	belong	VBG
cord-256444-grw5s2pf	218	4	to	to	IN
cord-256444-grw5s2pf	218	5	the	the	DT
cord-256444-grw5s2pf	218	6	MHV	MHV	NNP
cord-256444-grw5s2pf	218	7	group	group	NN
cord-256444-grw5s2pf	218	8	possess	possess	VBP
cord-256444-grw5s2pf	218	9	the	the	DT
cord-256444-grw5s2pf	218	10	HE	HE	NNP
cord-256444-grw5s2pf	218	11	gene	gene	NN
cord-256444-grw5s2pf	218	12	(	(	-LRB-
cord-256444-grw5s2pf	218	13	Table	table	NN
cord-256444-grw5s2pf	218	14	I	i	CD
cord-256444-grw5s2pf	218	15	)	)	-RRB-
cord-256444-grw5s2pf	218	16	.	.	.
cord-256444-grw5s2pf	219	1	Even	even	RB
cord-256444-grw5s2pf	219	2	there	there	RB
cord-256444-grw5s2pf	219	3	,	,	,
cord-256444-grw5s2pf	219	4	not	not	RB
cord-256444-grw5s2pf	219	5	all	all	DT
cord-256444-grw5s2pf	219	6	virus	virus	NN
cord-256444-grw5s2pf	219	7	strains	strain	VBZ
cord-256444-grw5s2pf	219	8	within	within	IN
cord-256444-grw5s2pf	219	9	a	a	DT
cord-256444-grw5s2pf	219	10	species	species	NN
cord-256444-grw5s2pf	219	11	express	express	VBP
cord-256444-grw5s2pf	219	12	the	the	DT
cord-256444-grw5s2pf	219	13	HE	HE	NNP
cord-256444-grw5s2pf	219	14	protein	protein	NN
cord-256444-grw5s2pf	219	15	(	(	-LRB-
cord-256444-grw5s2pf	219	16	Luytjes	Luytjes	NNP
cord-256444-grw5s2pf	219	17	et	et	NNP
cord-256444-grw5s2pf	219	18	al	al	NNP
cord-256444-grw5s2pf	219	19	.	.	NNP
cord-256444-grw5s2pf	219	20	,	,	,
cord-256444-grw5s2pf	219	21	1988	1988	CD
cord-256444-grw5s2pf	219	22	;	;	:
cord-256444-grw5s2pf	219	23	.	.	.
cord-256444-grw5s2pf	220	1	As	as	IN
cord-256444-grw5s2pf	220	2	with	with	IN
cord-256444-grw5s2pf	220	3	many	many	JJ
cord-256444-grw5s2pf	220	4	of	of	IN
cord-256444-grw5s2pf	220	5	the	the	DT
cord-256444-grw5s2pf	220	6	so	so	RB
cord-256444-grw5s2pf	220	7	-	-	HYPH
cord-256444-grw5s2pf	220	8	called	call	VBN
cord-256444-grw5s2pf	220	9	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	220	10	protein	protein	NN
cord-256444-grw5s2pf	220	11	genes	gene	NNS
cord-256444-grw5s2pf	220	12	of	of	IN
cord-256444-grw5s2pf	220	13	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	220	14	,	,	,
cord-256444-grw5s2pf	220	15	the	the	DT
cord-256444-grw5s2pf	220	16	product	product	NN
cord-256444-grw5s2pf	220	17	of	of	IN
cord-256444-grw5s2pf	220	18	the	the	DT
cord-256444-grw5s2pf	220	19	HE	HE	NNP
cord-256444-grw5s2pf	220	20	gene	gene	NN
cord-256444-grw5s2pf	220	21	is	be	VBZ
cord-256444-grw5s2pf	220	22	not	not	RB
cord-256444-grw5s2pf	220	23	essential	essential	JJ
cord-256444-grw5s2pf	220	24	for	for	IN
cord-256444-grw5s2pf	220	25	viral	viral	JJ
cord-256444-grw5s2pf	220	26	replication	replication	NN
cord-256444-grw5s2pf	220	27	,	,	,
cord-256444-grw5s2pf	220	28	certainly	certainly	RB
cord-256444-grw5s2pf	220	29	not	not	RB
cord-256444-grw5s2pf	220	30	in	in	IN
cord-256444-grw5s2pf	220	31	the	the	DT
cord-256444-grw5s2pf	220	32	cell	cell	NN
cord-256444-grw5s2pf	220	33	types	type	NNS
cord-256444-grw5s2pf	220	34	used	use	VBN
cord-256444-grw5s2pf	220	35	in	in	IN
cord-256444-grw5s2pf	220	36	the	the	DT
cord-256444-grw5s2pf	220	37	laboratory	laboratory	NN
cord-256444-grw5s2pf	220	38	.	.	.
cord-256444-grw5s2pf	221	1	The	the	DT
cord-256444-grw5s2pf	221	2	HE	HE	NNP
cord-256444-grw5s2pf	221	3	protein	protein	NN
cord-256444-grw5s2pf	221	4	was	be	VBD
cord-256444-grw5s2pf	221	5	first	first	RB
cord-256444-grw5s2pf	221	6	detected	detect	VBN
cord-256444-grw5s2pf	221	7	in	in	IN
cord-256444-grw5s2pf	221	8	BCV	BCV	NNP
cord-256444-grw5s2pf	221	9	(	(	-LRB-
cord-256444-grw5s2pf	221	10	King	King	NNP
cord-256444-grw5s2pf	221	11	et	et	NNP
cord-256444-grw5s2pf	221	12	al	al	NNP
cord-256444-grw5s2pf	221	13	.	.	NNP
cord-256444-grw5s2pf	221	14	,	,	,
cord-256444-grw5s2pf	221	15	1985	1985	CD
cord-256444-grw5s2pf	221	16	)	)	-RRB-
cord-256444-grw5s2pf	221	17	and	and	CC
cord-256444-grw5s2pf	221	18	some	some	DT
cord-256444-grw5s2pf	221	19	MHV	MHV	NNP
cord-256444-grw5s2pf	221	20	strains	strain	NNS
cord-256444-grw5s2pf	221	21	;	;	:
cord-256444-grw5s2pf	221	22	however	however	RB
cord-256444-grw5s2pf	221	23	,	,	,
cord-256444-grw5s2pf	221	24	acceptance	acceptance	NN
cord-256444-grw5s2pf	221	25	of	of	IN
cord-256444-grw5s2pf	221	26	it	-PRON-	PRP
cord-256444-grw5s2pf	221	27	as	as	IN
cord-256444-grw5s2pf	221	28	a	a	DT
cord-256444-grw5s2pf	221	29	legitimate	legitimate	JJ
cord-256444-grw5s2pf	221	30	virus	virus	NN
cord-256444-grw5s2pf	221	31	-	-	HYPH
cord-256444-grw5s2pf	221	32	encoded	encode	VBN
cord-256444-grw5s2pf	221	33	protein	protein	NN
cord-256444-grw5s2pf	221	34	was	be	VBD
cord-256444-grw5s2pf	221	35	delayed	delay	VBN
cord-256444-grw5s2pf	221	36	because	because	IN
cord-256444-grw5s2pf	221	37	in	in	IN
cord-256444-grw5s2pf	221	38	one	one	CD
cord-256444-grw5s2pf	221	39	of	of	IN
cord-256444-grw5s2pf	221	40	the	the	DT
cord-256444-grw5s2pf	221	41	MHV	MHV	NNP
cord-256444-grw5s2pf	221	42	strains	strain	NNS
cord-256444-grw5s2pf	221	43	studied	study	VBD
cord-256444-grw5s2pf	221	44	most	most	RBS
cord-256444-grw5s2pf	221	45	thoroughly	thoroughly	RB
cord-256444-grw5s2pf	221	46	,	,	,
cord-256444-grw5s2pf	221	47	A59	A59	NNP
cord-256444-grw5s2pf	221	48	,	,	,
cord-256444-grw5s2pf	221	49	virions	virion	NNS
cord-256444-grw5s2pf	221	50	lacked	lack	VBD
cord-256444-grw5s2pf	221	51	HE	he	PRP
cord-256444-grw5s2pf	221	52	.	.	.
cord-256444-grw5s2pf	222	1	The	the	DT
cord-256444-grw5s2pf	222	2	HE	HE	NNP
cord-256444-grw5s2pf	222	3	gene	gene	NN
cord-256444-grw5s2pf	222	4	of	of	IN
cord-256444-grw5s2pf	222	5	A59	A59	NNP
cord-256444-grw5s2pf	222	6	was	be	VBD
cord-256444-grw5s2pf	222	7	later	later	RB
cord-256444-grw5s2pf	222	8	shown	show	VBN
cord-256444-grw5s2pf	222	9	to	to	TO
cord-256444-grw5s2pf	222	10	lack	lack	VB
cord-256444-grw5s2pf	222	11	the	the	DT
cord-256444-grw5s2pf	222	12	initiation	initiation	NN
cord-256444-grw5s2pf	222	13	codon	codon	NN
cord-256444-grw5s2pf	222	14	of	of	IN
cord-256444-grw5s2pf	222	15	the	the	DT
cord-256444-grw5s2pf	222	16	HE	HE	NNP
cord-256444-grw5s2pf	222	17	open	open	JJ
cord-256444-grw5s2pf	222	18	reading	reading	NN
cord-256444-grw5s2pf	222	19	frame	frame	NN
cord-256444-grw5s2pf	222	20	(	(	-LRB-
cord-256444-grw5s2pf	222	21	ORF	ORF	NNP
cord-256444-grw5s2pf	222	22	)	)	-RRB-
cord-256444-grw5s2pf	222	23	;	;	:
cord-256444-grw5s2pf	222	24	thus	thus	RB
cord-256444-grw5s2pf	222	25	,	,	,
cord-256444-grw5s2pf	222	26	the	the	DT
cord-256444-grw5s2pf	222	27	HE	HE	NNP
cord-256444-grw5s2pf	222	28	gene	gene	NN
cord-256444-grw5s2pf	222	29	is	be	VBZ
cord-256444-grw5s2pf	222	30	a	a	DT
cord-256444-grw5s2pf	222	31	pseudogene	pseudogene	NN
cord-256444-grw5s2pf	222	32	in	in	IN
cord-256444-grw5s2pf	222	33	this	this	DT
cord-256444-grw5s2pf	222	34	(	(	-LRB-
cord-256444-grw5s2pf	222	35	Luytjes	Luytjes	NNP
cord-256444-grw5s2pf	222	36	et	et	NNP
cord-256444-grw5s2pf	222	37	aZ.	az.	NN
cord-256444-grw5s2pf	222	38	,	,	,
cord-256444-grw5s2pf	222	39	1988	1988	CD
cord-256444-grw5s2pf	222	40	)	)	-RRB-
cord-256444-grw5s2pf	222	41	and	and	CC
cord-256444-grw5s2pf	222	42	several	several	JJ
cord-256444-grw5s2pf	222	43	other	other	JJ
cord-256444-grw5s2pf	222	44	MHV	MHV	NNP
cord-256444-grw5s2pf	222	45	strains	strain	NNS
cord-256444-grw5s2pf	222	46	.	.	.
cord-256444-grw5s2pf	223	1	A	a	DT
cord-256444-grw5s2pf	223	2	complete	complete	JJ
cord-256444-grw5s2pf	223	3	,	,	,
cord-256444-grw5s2pf	223	4	functional	functional	JJ
cord-256444-grw5s2pf	223	5	HE	HE	NNP
cord-256444-grw5s2pf	223	6	gene	gene	NN
cord-256444-grw5s2pf	223	7	was	be	VBD
cord-256444-grw5s2pf	223	8	subsequently	subsequently	RB
cord-256444-grw5s2pf	223	9	identified	identify	VBN
cord-256444-grw5s2pf	223	10	in	in	IN
cord-256444-grw5s2pf	223	11	the	the	DT
cord-256444-grw5s2pf	223	12	JHM	JHM	NNP
cord-256444-grw5s2pf	223	13	strain	strain	NN
cord-256444-grw5s2pf	223	14	and	and	CC
cord-256444-grw5s2pf	223	15	several	several	JJ
cord-256444-grw5s2pf	223	16	others	other	NNS
cord-256444-grw5s2pf	223	17	.	.	.
cord-256444-grw5s2pf	224	1	The	the	DT
cord-256444-grw5s2pf	224	2	HE	HE	NNP
cord-256444-grw5s2pf	224	3	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	224	4	,	,	,
cord-256444-grw5s2pf	224	5	of	of	IN
cord-256444-grw5s2pf	224	6	approximately	approximately	RB
cord-256444-grw5s2pf	224	7	65	65	CD
cord-256444-grw5s2pf	224	8	kDa	kDa	NNS
cord-256444-grw5s2pf	224	9	(	(	-LRB-
cord-256444-grw5s2pf	224	10	424	424	CD
cord-256444-grw5s2pf	224	11	amino	amino	JJ
cord-256444-grw5s2pf	224	12	acids	acid	NNS
cord-256444-grw5s2pf	224	13	in	in	IN
cord-256444-grw5s2pf	224	14	BCV	BCV	NNP
cord-256444-grw5s2pf	224	15	)	)	-RRB-
cord-256444-grw5s2pf	224	16	,	,	,
cord-256444-grw5s2pf	224	17	has	have	VBZ
cord-256444-grw5s2pf	224	18	been	be	VBN
cord-256444-grw5s2pf	224	19	detected	detect	VBN
cord-256444-grw5s2pf	224	20	in	in	IN
cord-256444-grw5s2pf	224	21	virions	virion	NNS
cord-256444-grw5s2pf	224	22	of	of	IN
cord-256444-grw5s2pf	224	23	HEV	hev	NN
cord-256444-grw5s2pf	224	24	,	,	,
cord-256444-grw5s2pf	224	25	MHV	MHV	NNP
cord-256444-grw5s2pf	224	26	,	,	,
cord-256444-grw5s2pf	224	27	HCV	HCV	NNP
cord-256444-grw5s2pf	224	28	-	-	HYPH
cord-256444-grw5s2pf	224	29	OC43	OC43	NNP
cord-256444-grw5s2pf	224	30	,	,	,
cord-256444-grw5s2pf	224	31	BCV	BCV	NNP
cord-256444-grw5s2pf	224	32	,	,	,
cord-256444-grw5s2pf	224	33	and	and	CC
cord-256444-grw5s2pf	224	34	TCV	TCV	NNP
cord-256444-grw5s2pf	224	35	.	.	.
cord-256444-grw5s2pf	225	1	When	when	WRB
cord-256444-grw5s2pf	225	2	analyzed	analyze	VBN
cord-256444-grw5s2pf	225	3	under	under	IN
cord-256444-grw5s2pf	225	4	nonreducing	nonreducing	NN
cord-256444-grw5s2pf	225	5	conditions	condition	NNS
cord-256444-grw5s2pf	225	6	,	,	,
cord-256444-grw5s2pf	225	7	the	the	DT
cord-256444-grw5s2pf	225	8	HE	HE	NNP
cord-256444-grw5s2pf	225	9	protein	protein	NN
cord-256444-grw5s2pf	225	10	migrates	migrate	VBZ
cord-256444-grw5s2pf	225	11	as	as	IN
cord-256444-grw5s2pf	225	12	a	a	DT
cord-256444-grw5s2pf	225	13	dimer	dimer	NN
cord-256444-grw5s2pf	225	14	of	of	IN
cord-256444-grw5s2pf	225	15	approximately	approximately	RB
cord-256444-grw5s2pf	225	16	140	140	CD
cord-256444-grw5s2pf	225	17	kDa	kDa	NNS
cord-256444-grw5s2pf	225	18	(	(	-LRB-
cord-256444-grw5s2pf	225	19	King	King	NNP
cord-256444-grw5s2pf	225	20	et	et	NNP
cord-256444-grw5s2pf	225	21	al	al	NNP
cord-256444-grw5s2pf	225	22	.	.	NNP
cord-256444-grw5s2pf	225	23	,	,	,
cord-256444-grw5s2pf	225	24	1985	1985	CD
cord-256444-grw5s2pf	225	25	)	)	-RRB-
cord-256444-grw5s2pf	225	26	.	.	.
cord-256444-grw5s2pf	226	1	The	the	DT
cord-256444-grw5s2pf	226	2	mature	mature	JJ
cord-256444-grw5s2pf	226	3	protein	protein	NN
cord-256444-grw5s2pf	226	4	is	be	VBZ
cord-256444-grw5s2pf	226	5	believed	believe	VBN
cord-256444-grw5s2pf	226	6	to	to	TO
cord-256444-grw5s2pf	226	7	exist	exist	VB
cord-256444-grw5s2pf	226	8	in	in	IN
cord-256444-grw5s2pf	226	9	the	the	DT
cord-256444-grw5s2pf	226	10	virion	virion	NN
cord-256444-grw5s2pf	226	11	as	as	IN
cord-256444-grw5s2pf	226	12	a	a	DT
cord-256444-grw5s2pf	226	13	dimer	dimer	NN
cord-256444-grw5s2pf	226	14	,	,	,
cord-256444-grw5s2pf	226	15	anchored	anchor	VBN
cord-256444-grw5s2pf	226	16	by	by	IN
cord-256444-grw5s2pf	226	17	the	the	DT
cord-256444-grw5s2pf	226	18	C	C	NNP
cord-256444-grw5s2pf	226	19	terminus	terminus	NN
cord-256444-grw5s2pf	226	20	,	,	,
cord-256444-grw5s2pf	226	21	forming	form	VBG
cord-256444-grw5s2pf	226	22	a	a	DT
cord-256444-grw5s2pf	226	23	fringe	fringe	NN
cord-256444-grw5s2pf	226	24	of	of	IN
cord-256444-grw5s2pf	226	25	short	short	JJ
cord-256444-grw5s2pf	226	26	spikes	spike	NNS
cord-256444-grw5s2pf	226	27	visualized	visualize	VBN
cord-256444-grw5s2pf	226	28	by	by	IN
cord-256444-grw5s2pf	226	29	electron	electron	NN
cord-256444-grw5s2pf	226	30	microscopy	microscopy	NNS
cord-256444-grw5s2pf	226	31	(	(	-LRB-
cord-256444-grw5s2pf	226	32	Caul	Caul	NNP
cord-256444-grw5s2pf	226	33	and	and	CC
cord-256444-grw5s2pf	226	34	Egglestone	Egglestone	NNP
cord-256444-grw5s2pf	226	35	,	,	,
cord-256444-grw5s2pf	226	36	1977	1977	CD
cord-256444-grw5s2pf	226	37	;	;	:
cord-256444-grw5s2pf	226	38	Dea	Dea	NNP
cord-256444-grw5s2pf	226	39	and	and	CC
cord-256444-grw5s2pf	226	40	Tijssen	Tijssen	NNP
cord-256444-grw5s2pf	226	41	,	,	,
cord-256444-grw5s2pf	226	42	1988	1988	CD
cord-256444-grw5s2pf	226	43	)	)	-RRB-
cord-256444-grw5s2pf	226	44	.	.	.
cord-256444-grw5s2pf	227	1	It	-PRON-	PRP
cord-256444-grw5s2pf	227	2	is	be	VBZ
cord-256444-grw5s2pf	227	3	not	not	RB
cord-256444-grw5s2pf	227	4	known	know	VBN
cord-256444-grw5s2pf	227	5	whether	whether	IN
cord-256444-grw5s2pf	227	6	each	each	DT
cord-256444-grw5s2pf	227	7	spike	spike	NN
cord-256444-grw5s2pf	227	8	consists	consist	VBZ
cord-256444-grw5s2pf	227	9	of	of	IN
cord-256444-grw5s2pf	227	10	more	more	JJR
cord-256444-grw5s2pf	227	11	than	than	IN
cord-256444-grw5s2pf	227	12	one	one	CD
cord-256444-grw5s2pf	227	13	HE	HE	NNP
cord-256444-grw5s2pf	227	14	dimer	dimer	NN
cord-256444-grw5s2pf	227	15	.	.	.
cord-256444-grw5s2pf	228	1	Those	those	DT
cord-256444-grw5s2pf	228	2	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	228	3	which	which	WDT
cord-256444-grw5s2pf	228	4	contain	contain	VBP
cord-256444-grw5s2pf	228	5	HE	he	PRP
cord-256444-grw5s2pf	228	6	in	in	IN
cord-256444-grw5s2pf	228	7	their	-PRON-	PRP$
cord-256444-grw5s2pf	228	8	virions	virion	NNS
cord-256444-grw5s2pf	228	9	cause	cause	VBP
cord-256444-grw5s2pf	228	10	hemagglutination	hemagglutination	NN
cord-256444-grw5s2pf	228	11	much	much	RB
cord-256444-grw5s2pf	228	12	more	more	RBR
cord-256444-grw5s2pf	228	13	efficiently	efficiently	RB
cord-256444-grw5s2pf	228	14	than	than	IN
cord-256444-grw5s2pf	228	15	those	those	DT
cord-256444-grw5s2pf	228	16	that	that	WDT
cord-256444-grw5s2pf	228	17	do	do	VBP
cord-256444-grw5s2pf	228	18	not	not	RB
cord-256444-grw5s2pf	228	19	.	.	.
cord-256444-grw5s2pf	229	1	Similar	similar	JJ
cord-256444-grw5s2pf	229	2	to	to	IN
cord-256444-grw5s2pf	229	3	the	the	DT
cord-256444-grw5s2pf	229	4	S	S	NNP
cord-256444-grw5s2pf	229	5	protein	protein	NN
cord-256444-grw5s2pf	229	6	,	,	,
cord-256444-grw5s2pf	229	7	HE	he	PRP
cord-256444-grw5s2pf	229	8	alone	alone	RB
cord-256444-grw5s2pf	229	9	can	can	MD
cord-256444-grw5s2pf	229	10	mediate	mediate	VB
cord-256444-grw5s2pf	229	11	hemagglutination	hemagglutination	NN
cord-256444-grw5s2pf	229	12	and	and	CC
cord-256444-grw5s2pf	229	13	hemadsorption	hemadsorption	NN
cord-256444-grw5s2pf	230	1	(	(	-LRB-
cord-256444-grw5s2pf	230	2	King	King	NNP
cord-256444-grw5s2pf	230	3	et	et	NNP
cord-256444-grw5s2pf	230	4	al	al	NNP
cord-256444-grw5s2pf	230	5	.	.	NNP
cord-256444-grw5s2pf	230	6	,	,	,
cord-256444-grw5s2pf	230	7	1985	1985	CD
cord-256444-grw5s2pf	230	8	;	;	:
cord-256444-grw5s2pf	230	9	Hogue	Hogue	NNP
cord-256444-grw5s2pf	230	10	and	and	CC
cord-256444-grw5s2pf	230	11	Brian	Brian	NNP
cord-256444-grw5s2pf	230	12	,	,	,
cord-256444-grw5s2pf	230	13	1986	1986	CD
cord-256444-grw5s2pf	230	14	;	;	:
cord-256444-grw5s2pf	230	15	Vlasak	Vlasak	NNP
cord-256444-grw5s2pf	230	16	et	et	NNP
cord-256444-grw5s2pf	230	17	al	al	NNP
cord-256444-grw5s2pf	230	18	.	.	NNP
cord-256444-grw5s2pf	230	19	,	,	,
cord-256444-grw5s2pf	230	20	1988b	1988b	CD
cord-256444-grw5s2pf	230	21	;	;	:
cord-256444-grw5s2pf	231	1	Deregt	Deregt	NNP
cord-256444-grw5s2pf	231	2	et	et	FW
cord-256444-grw5s2pf	231	3	al	al	NNP
cord-256444-grw5s2pf	231	4	.	.	.
cord-256444-grw5s2pf	232	1	,	,	,
cord-256444-grw5s2pf	232	2	1989	1989	CD
cord-256444-grw5s2pf	232	3	;	;	:
cord-256444-grw5s2pf	232	4	Pfleiderer	Pfleiderer	NNP
cord-256444-grw5s2pf	232	5	et	et	NNP
cord-256444-grw5s2pf	232	6	al	al	NNP
cord-256444-grw5s2pf	232	7	.	.	NNP
cord-256444-grw5s2pf	232	8	,	,	,
cord-256444-grw5s2pf	232	9	1991	1991	CD
cord-256444-grw5s2pf	233	1	;	;	:
cord-256444-grw5s2pf	233	2	Schultze	Schultze	NNP
cord-256444-grw5s2pf	233	3	et	et	NNP
cord-256444-grw5s2pf	233	4	al	al	NNP
cord-256444-grw5s2pf	233	5	.	.	NNP
cord-256444-grw5s2pf	233	6	,	,	,
cord-256444-grw5s2pf	233	7	1991a	1991a	CD
cord-256444-grw5s2pf	233	8	)	)	-RRB-
cord-256444-grw5s2pf	233	9	;	;	:
cord-256444-grw5s2pf	233	10	however	however	RB
cord-256444-grw5s2pf	233	11	,	,	,
cord-256444-grw5s2pf	233	12	HE	he	PRP
cord-256444-grw5s2pf	233	13	seems	seem	VBZ
cord-256444-grw5s2pf	233	14	to	to	TO
cord-256444-grw5s2pf	233	15	have	have	VB
cord-256444-grw5s2pf	233	16	weaker	weak	JJR
cord-256444-grw5s2pf	233	17	activity	activity	NN
cord-256444-grw5s2pf	233	18	than	than	IN
cord-256444-grw5s2pf	233	19	S	S	NNP
cord-256444-grw5s2pf	233	20	(	(	-LRB-
cord-256444-grw5s2pf	233	21	Schultze	Schultze	NNP
cord-256444-grw5s2pf	233	22	et	et	NNP
cord-256444-grw5s2pf	233	23	al	al	NNP
cord-256444-grw5s2pf	233	24	.	.	NNP
cord-256444-grw5s2pf	233	25	,	,	,
cord-256444-grw5s2pf	233	26	1991a	1991a	CD
cord-256444-grw5s2pf	233	27	)	)	-RRB-
cord-256444-grw5s2pf	233	28	.	.	.
cord-256444-grw5s2pf	234	1	HE	he	PRP
cord-256444-grw5s2pf	234	2	binds	bind	VBZ
cord-256444-grw5s2pf	234	3	to	to	IN
cord-256444-grw5s2pf	234	4	9-O	9-o	CD
cord-256444-grw5s2pf	234	5	-	-	HYPH
cord-256444-grw5s2pf	234	6	acetylated	acetylated	JJ
cord-256444-grw5s2pf	234	7	neuraminic	neuraminic	JJ
cord-256444-grw5s2pf	234	8	acid	acid	NN
cord-256444-grw5s2pf	234	9	(	(	-LRB-
cord-256444-grw5s2pf	234	10	Vlasak	Vlasak	NNP
cord-256444-grw5s2pf	234	11	et	et	NNP
cord-256444-grw5s2pf	234	12	al	al	NNP
cord-256444-grw5s2pf	234	13	.	.	NNP
cord-256444-grw5s2pf	234	14	,	,	,
cord-256444-grw5s2pf	234	15	198813	198813	CD
cord-256444-grw5s2pf	234	16	;	;	:
cord-256444-grw5s2pf	235	1	Schultze	Schultze	NNP
cord-256444-grw5s2pf	235	2	et	et	NNP
cord-256444-grw5s2pf	235	3	al	al	NNP
cord-256444-grw5s2pf	235	4	.	.	NNP
cord-256444-grw5s2pf	235	5	,	,	,
cord-256444-grw5s2pf	235	6	1991a	1991a	CD
cord-256444-grw5s2pf	235	7	)	)	-RRB-
cord-256444-grw5s2pf	235	8	,	,	,
cord-256444-grw5s2pf	235	9	which	which	WDT
cord-256444-grw5s2pf	235	10	is	be	VBZ
cord-256444-grw5s2pf	235	11	also	also	RB
cord-256444-grw5s2pf	235	12	a	a	DT
cord-256444-grw5s2pf	235	13	target	target	NN
cord-256444-grw5s2pf	235	14	for	for	IN
cord-256444-grw5s2pf	235	15	S	s	NN
cord-256444-grw5s2pf	235	16	binding	binding	NN
cord-256444-grw5s2pf	235	17	.	.	.
cord-256444-grw5s2pf	236	1	Some	some	DT
cord-256444-grw5s2pf	236	2	HE	HE	NNP
cord-256444-grw5s2pf	236	3	-	-	HYPH
cord-256444-grw5s2pf	236	4	specific	specific	JJ
cord-256444-grw5s2pf	236	5	MAb	MAb	NNS
cord-256444-grw5s2pf	236	6	can	can	MD
cord-256444-grw5s2pf	236	7	neutralize	neutralize	VB
cord-256444-grw5s2pf	236	8	BCV	BCV	NNP
cord-256444-grw5s2pf	236	9	infectivity	infectivity	NN
cord-256444-grw5s2pf	236	10	(	(	-LRB-
cord-256444-grw5s2pf	236	11	Deregt	Deregt	NNP
cord-256444-grw5s2pf	236	12	and	and	CC
cord-256444-grw5s2pf	236	13	Babiuk	Babiuk	NNP
cord-256444-grw5s2pf	236	14	,	,	,
cord-256444-grw5s2pf	236	15	1987	1987	CD
cord-256444-grw5s2pf	236	16	;	;	:
cord-256444-grw5s2pf	236	17	Deregt	Deregt	NNP
cord-256444-grw5s2pf	236	18	et	et	NNP
cord-256444-grw5s2pf	236	19	al	al	NNP
cord-256444-grw5s2pf	236	20	.	.	NNP
cord-256444-grw5s2pf	236	21	,	,	,
cord-256444-grw5s2pf	236	22	1989	1989	CD
cord-256444-grw5s2pf	236	23	)	)	-RRB-
cord-256444-grw5s2pf	236	24	.	.	.
cord-256444-grw5s2pf	237	1	Thus	thus	RB
cord-256444-grw5s2pf	237	2	,	,	,
cord-256444-grw5s2pf	237	3	HE	HE	NNP
cord-256444-grw5s2pf	237	4	protein	protein	NN
cord-256444-grw5s2pf	237	5	of	of	IN
cord-256444-grw5s2pf	237	6	BCV	BCV	NNP
cord-256444-grw5s2pf	237	7	may	may	MD
cord-256444-grw5s2pf	237	8	participate	participate	VB
cord-256444-grw5s2pf	237	9	in	in	IN
cord-256444-grw5s2pf	237	10	virus	virus	NN
cord-256444-grw5s2pf	237	11	binding	bind	VBG
cord-256444-grw5s2pf	237	12	to	to	IN
cord-256444-grw5s2pf	237	13	the	the	DT
cord-256444-grw5s2pf	237	14	receptor	receptor	NN
cord-256444-grw5s2pf	237	15	.	.	.
cord-256444-grw5s2pf	238	1	The	the	DT
cord-256444-grw5s2pf	238	2	relative	relative	JJ
cord-256444-grw5s2pf	238	3	importance	importance	NN
cord-256444-grw5s2pf	238	4	of	of	IN
cord-256444-grw5s2pf	238	5	HE	HE	NNP
cord-256444-grw5s2pf	238	6	and	and	CC
cord-256444-grw5s2pf	238	7	S	S	NNP
cord-256444-grw5s2pf	238	8	in	in	IN
cord-256444-grw5s2pf	238	9	hemagglutination	hemagglutination	NN
cord-256444-grw5s2pf	238	10	and	and	CC
cord-256444-grw5s2pf	238	11	tissue	tissue	NN
cord-256444-grw5s2pf	238	12	tropism	tropism	NN
cord-256444-grw5s2pf	238	13	of	of	IN
cord-256444-grw5s2pf	238	14	BCV	BCV	NNP
cord-256444-grw5s2pf	238	15	is	be	VBZ
cord-256444-grw5s2pf	238	16	not	not	RB
cord-256444-grw5s2pf	238	17	known	know	VBN
cord-256444-grw5s2pf	238	18	.	.	.
cord-256444-grw5s2pf	239	1	As	as	IN
cord-256444-grw5s2pf	239	2	its	-PRON-	PRP$
cord-256444-grw5s2pf	239	3	name	name	NN
cord-256444-grw5s2pf	239	4	implies	imply	VBZ
cord-256444-grw5s2pf	239	5	,	,	,
cord-256444-grw5s2pf	239	6	the	the	DT
cord-256444-grw5s2pf	239	7	HE	HE	NNP
cord-256444-grw5s2pf	239	8	protein	protein	NN
cord-256444-grw5s2pf	239	9	also	also	RB
cord-256444-grw5s2pf	239	10	has	have	VBZ
cord-256444-grw5s2pf	239	11	esterase	esterase	NN
cord-256444-grw5s2pf	239	12	activity	activity	NN
cord-256444-grw5s2pf	239	13	;	;	:
cord-256444-grw5s2pf	239	14	specifically	specifically	RB
cord-256444-grw5s2pf	239	15	,	,	,
cord-256444-grw5s2pf	239	16	it	-PRON-	PRP
cord-256444-grw5s2pf	239	17	is	be	VBZ
cord-256444-grw5s2pf	239	18	a	a	DT
cord-256444-grw5s2pf	239	19	neuraminate	neuraminate	NN
cord-256444-grw5s2pf	239	20	-	-	HYPH
cord-256444-grw5s2pf	239	21	O	o	NN
cord-256444-grw5s2pf	239	22	-	-	HYPH
cord-256444-grw5s2pf	239	23	acetylesterase	acetylesterase	NN
cord-256444-grw5s2pf	239	24	.	.	.
cord-256444-grw5s2pf	240	1	It	-PRON-	PRP
cord-256444-grw5s2pf	240	2	hydrolyzes	hydrolyze	VBZ
cord-256444-grw5s2pf	240	3	the	the	DT
cord-256444-grw5s2pf	240	4	9	9	CD
cord-256444-grw5s2pf	240	5	-	-	HYPH
cord-256444-grw5s2pf	240	6	0acetylated	0acetylated	CD
cord-256444-grw5s2pf	240	7	sialic	sialic	JJ
cord-256444-grw5s2pf	240	8	acid	acid	NN
cord-256444-grw5s2pf	240	9	on	on	IN
cord-256444-grw5s2pf	240	10	erythrocytes	erythrocyte	NNS
cord-256444-grw5s2pf	240	11	,	,	,
cord-256444-grw5s2pf	240	12	thereby	thereby	RB
cord-256444-grw5s2pf	240	13	reversing	reverse	VBG
cord-256444-grw5s2pf	240	14	hemagglutination	hemagglutination	NN
cord-256444-grw5s2pf	240	15	induced	induce	VBN
cord-256444-grw5s2pf	240	16	by	by	IN
cord-256444-grw5s2pf	240	17	the	the	DT
cord-256444-grw5s2pf	240	18	HE	HE	NNP
cord-256444-grw5s2pf	240	19	or	or	CC
cord-256444-grw5s2pf	240	20	S	S	NNP
cord-256444-grw5s2pf	240	21	protein	protein	NN
cord-256444-grw5s2pf	240	22	;	;	:
cord-256444-grw5s2pf	240	23	thus	thus	RB
cord-256444-grw5s2pf	240	24	,	,	,
cord-256444-grw5s2pf	240	25	HE	he	PRP
cord-256444-grw5s2pf	240	26	is	be	VBZ
cord-256444-grw5s2pf	240	27	considered	consider	VBN
cord-256444-grw5s2pf	240	28	a	a	DT
cord-256444-grw5s2pf	240	29	receptordestroying	receptordestroye	VBG
cord-256444-grw5s2pf	240	30	enzyme	enzyme	NN
cord-256444-grw5s2pf	240	31	(	(	-LRB-
cord-256444-grw5s2pf	240	32	Vlasaket	Vlasaket	NNP
cord-256444-grw5s2pf	240	33	aZ.	az.	NN
cord-256444-grw5s2pf	240	34	,	,	,
cord-256444-grw5s2pf	240	35	1988a	1988a	CD
cord-256444-grw5s2pf	240	36	,	,	,
cord-256444-grw5s2pf	240	37	b	b	LS
cord-256444-grw5s2pf	240	38	;	;	:
cord-256444-grw5s2pf	240	39	Yokomori	Yokomori	NNP
cord-256444-grw5s2pf	240	40	et	et	NNP
cord-256444-grw5s2pf	240	41	aZ.	az.	NN
cord-256444-grw5s2pf	240	42	,	,	,
cord-256444-grw5s2pf	240	43	1989	1989	CD
cord-256444-grw5s2pf	240	44	;	;	:
cord-256444-grw5s2pf	240	45	.	.	.
cord-256444-grw5s2pf	241	1	The	the	DT
cord-256444-grw5s2pf	241	2	putative	putative	JJ
cord-256444-grw5s2pf	241	3	esterase	esterase	NN
cord-256444-grw5s2pf	241	4	active	active	JJ
cord-256444-grw5s2pf	241	5	site	site	NN
cord-256444-grw5s2pf	241	6	is	be	VBZ
cord-256444-grw5s2pf	241	7	FGDS	FGDS	NNP
cord-256444-grw5s2pf	241	8	,	,	,
cord-256444-grw5s2pf	241	9	encoded	encode	VBN
cord-256444-grw5s2pf	241	10	by	by	IN
cord-256444-grw5s2pf	241	11	amino	amino	JJ
cord-256444-grw5s2pf	241	12	acids	acid	NNS
cord-256444-grw5s2pf	241	13	19	19	CD
cord-256444-grw5s2pf	241	14	-	-	SYM
cord-256444-grw5s2pf	241	15	22	22	CD
cord-256444-grw5s2pf	241	16	of	of	IN
cord-256444-grw5s2pf	241	17	the	the	DT
cord-256444-grw5s2pf	241	18	mature	mature	JJ
cord-256444-grw5s2pf	241	19	HE	HE	NNP
cord-256444-grw5s2pf	241	20	polypeptide	polypeptide	NN
cord-256444-grw5s2pf	241	21	of	of	IN
cord-256444-grw5s2pf	241	22	BCV	BCV	NNP
cord-256444-grw5s2pf	241	23	(	(	-LRB-
cord-256444-grw5s2pf	241	24	M.	M.	NNP
cord-256444-grw5s2pf	241	25	D.	D.	NNP
cord-256444-grw5s2pf	241	26	Parker	Parker	NNP
cord-256444-grw5s2pf	241	27	et	et	NNP
cord-256444-grw5s2pf	241	28	al	al	NNP
cord-256444-grw5s2pf	241	29	.	.	NNP
cord-256444-grw5s2pf	241	30	,	,	,
cord-256444-grw5s2pf	241	31	1989	1989	CD
cord-256444-grw5s2pf	241	32	;	;	:
cord-256444-grw5s2pf	241	33	Kienzle	Kienzle	NNP
cord-256444-grw5s2pf	241	34	et	et	NNP
cord-256444-grw5s2pf	241	35	al	al	NNP
cord-256444-grw5s2pf	241	36	.	.	NNP
cord-256444-grw5s2pf	241	37	,	,	,
cord-256444-grw5s2pf	241	38	1990	1990	CD
cord-256444-grw5s2pf	241	39	)	)	-RRB-
cord-256444-grw5s2pf	241	40	.	.	.
cord-256444-grw5s2pf	242	1	In	in	IN
cord-256444-grw5s2pf	242	2	these	these	DT
cord-256444-grw5s2pf	242	3	respects	respect	NNS
cord-256444-grw5s2pf	242	4	,	,	,
cord-256444-grw5s2pf	242	5	it	-PRON-	PRP
cord-256444-grw5s2pf	242	6	resembles	resemble	VBZ
cord-256444-grw5s2pf	242	7	the	the	DT
cord-256444-grw5s2pf	242	8	hemagglutinin	hemagglutinin	NN
cord-256444-grw5s2pf	242	9	-	-	HYPH
cord-256444-grw5s2pf	242	10	esterase	esterase	NN
cord-256444-grw5s2pf	242	11	-	-	HYPH
cord-256444-grw5s2pf	242	12	fusion	fusion	NN
cord-256444-grw5s2pf	242	13	(	(	-LRB-
cord-256444-grw5s2pf	242	14	HEF	HEF	NNP
cord-256444-grw5s2pf	242	15	)	)	-RRB-
cord-256444-grw5s2pf	242	16	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	242	17	of	of	IN
cord-256444-grw5s2pf	242	18	influenza	influenza	NN
cord-256444-grw5s2pf	242	19	C	C	NNP
cord-256444-grw5s2pf	242	20	viruses	virus	NNS
cord-256444-grw5s2pf	242	21	,	,	,
cord-256444-grw5s2pf	242	22	which	which	WDT
cord-256444-grw5s2pf	242	23	also	also	RB
cord-256444-grw5s2pf	242	24	has	have	VBZ
cord-256444-grw5s2pf	242	25	hemagglutinating	hemagglutinating	NN
cord-256444-grw5s2pf	242	26	and	and	CC
cord-256444-grw5s2pf	242	27	9-O	9-o	CD
cord-256444-grw5s2pf	242	28	-	-	HYPH
cord-256444-grw5s2pf	242	29	acetylated	acetylated	JJ
cord-256444-grw5s2pf	243	1	sialic	sialic	JJ
cord-256444-grw5s2pf	243	2	acidhydrolyzing	acidhydrolyze	VBG
cord-256444-grw5s2pf	243	3	esterase	esterase	NN
cord-256444-grw5s2pf	243	4	activities	activity	NNS
cord-256444-grw5s2pf	243	5	.	.	.
cord-256444-grw5s2pf	244	1	Moreover	moreover	RB
cord-256444-grw5s2pf	244	2	,	,	,
cord-256444-grw5s2pf	244	3	the	the	DT
cord-256444-grw5s2pf	244	4	HE	HE	NNP
cord-256444-grw5s2pf	244	5	protein	protein	NN
cord-256444-grw5s2pf	244	6	of	of	IN
cord-256444-grw5s2pf	244	7	coronavi	coronavi	NN
cord-256444-grw5s2pf	244	8	-	-	HYPH
cord-256444-grw5s2pf	244	9	ruses	ruse	NNS
cord-256444-grw5s2pf	244	10	shares	share	NNS
cord-256444-grw5s2pf	244	11	some	some	DT
cord-256444-grw5s2pf	244	12	29	29	CD
cord-256444-grw5s2pf	244	13	%	%	NN
cord-256444-grw5s2pf	244	14	amino	amino	NN
cord-256444-grw5s2pf	244	15	acid	acid	NN
cord-256444-grw5s2pf	244	16	identity	identity	NN
cord-256444-grw5s2pf	244	17	with	with	IN
cord-256444-grw5s2pf	244	18	the	the	DT
cord-256444-grw5s2pf	244	19	HEF	HEF	NNP
cord-256444-grw5s2pf	244	20	of	of	IN
cord-256444-grw5s2pf	244	21	influenza	influenza	NN
cord-256444-grw5s2pf	244	22	C	C	NNP
cord-256444-grw5s2pf	244	23	virus	virus	NN
cord-256444-grw5s2pf	244	24	,	,	,
cord-256444-grw5s2pf	244	25	including	include	VBG
cord-256444-grw5s2pf	244	26	conservation	conservation	NN
cord-256444-grw5s2pf	244	27	of	of	IN
cord-256444-grw5s2pf	244	28	the	the	DT
cord-256444-grw5s2pf	244	29	position	position	NN
cord-256444-grw5s2pf	244	30	of	of	IN
cord-256444-grw5s2pf	244	31	the	the	DT
cord-256444-grw5s2pf	244	32	putative	putative	JJ
cord-256444-grw5s2pf	244	33	esteraseactive	esteraseactive	NN
cord-256444-grw5s2pf	244	34	site	site	NN
cord-256444-grw5s2pf	244	35	FGDS	FGDS	NNP
cord-256444-grw5s2pf	244	36	and	and	CC
cord-256444-grw5s2pf	244	37	many	many	JJ
cord-256444-grw5s2pf	244	38	cysteine	cysteine	NN
cord-256444-grw5s2pf	244	39	residues	residue	NNS
cord-256444-grw5s2pf	244	40	(	(	-LRB-
cord-256444-grw5s2pf	244	41	Luytjes	Luytjes	NNP
cord-256444-grw5s2pf	244	42	et	et	NNP
cord-256444-grw5s2pf	244	43	al	al	NNP
cord-256444-grw5s2pf	244	44	.	.	NNP
cord-256444-grw5s2pf	244	45	,	,	,
cord-256444-grw5s2pf	244	46	1988	1988	CD
cord-256444-grw5s2pf	244	47	;	;	:
cord-256444-grw5s2pf	244	48	 	 	_SP
cord-256444-grw5s2pf	244	49	S.	S.	NNP
cord-256444-grw5s2pf	244	50	E.	E.	NNP
cord-256444-grw5s2pf	244	51	Parkeret	Parkeret	NNP
cord-256444-grw5s2pf	244	52	al	al	NNP
cord-256444-grw5s2pf	244	53	.	.	NNP
cord-256444-grw5s2pf	244	54	,	,	,
cord-256444-grw5s2pf	244	55	1989	1989	CD
cord-256444-grw5s2pf	244	56	;	;	:
cord-256444-grw5s2pf	244	57	Kienzle	Kienzle	NNP
cord-256444-grw5s2pf	244	58	et	et	NNP
cord-256444-grw5s2pf	244	59	al	al	NNP
cord-256444-grw5s2pf	244	60	.	.	NNP
cord-256444-grw5s2pf	244	61	,	,	,
cord-256444-grw5s2pf	244	62	1990	1990	CD
cord-256444-grw5s2pf	244	63	;	;	:
cord-256444-grw5s2pf	244	64	Zhanget	Zhanget	NNP
cord-256444-grw5s2pf	244	65	al	al	NNP
cord-256444-grw5s2pf	244	66	.	.	NNP
cord-256444-grw5s2pf	244	67	,	,	,
cord-256444-grw5s2pf	244	68	1991	1991	CD
cord-256444-grw5s2pf	244	69	)	)	-RRB-
cord-256444-grw5s2pf	244	70	.	.	.
cord-256444-grw5s2pf	245	1	Unlike	unlike	IN
cord-256444-grw5s2pf	245	2	the	the	DT
cord-256444-grw5s2pf	245	3	HEF	HEF	NNP
cord-256444-grw5s2pf	245	4	protein	protein	NN
cord-256444-grw5s2pf	245	5	of	of	IN
cord-256444-grw5s2pf	245	6	influenza	influenza	NN
cord-256444-grw5s2pf	245	7	C	C	NNP
cord-256444-grw5s2pf	245	8	virus	virus	NN
cord-256444-grw5s2pf	245	9	,	,	,
cord-256444-grw5s2pf	245	10	which	which	WDT
cord-256444-grw5s2pf	245	11	is	be	VBZ
cord-256444-grw5s2pf	245	12	cleaved	cleave	VBN
cord-256444-grw5s2pf	245	13	into	into	IN
cord-256444-grw5s2pf	245	14	two	two	CD
cord-256444-grw5s2pf	245	15	subunits	subunit	NNS
cord-256444-grw5s2pf	245	16	(	(	-LRB-
cord-256444-grw5s2pf	245	17	Nakada	Nakada	NNP
cord-256444-grw5s2pf	245	18	et	et	NNP
cord-256444-grw5s2pf	245	19	al	al	NNP
cord-256444-grw5s2pf	245	20	.	.	NNP
cord-256444-grw5s2pf	245	21	,	,	,
cord-256444-grw5s2pf	245	22	19841	19841	CD
cord-256444-grw5s2pf	245	23	,	,	,
cord-256444-grw5s2pf	245	24	the	the	DT
cord-256444-grw5s2pf	245	25	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	245	26	HE	HE	NNP
cord-256444-grw5s2pf	245	27	protein	protein	NN
cord-256444-grw5s2pf	245	28	is	be	VBZ
cord-256444-grw5s2pf	245	29	not	not	RB
cord-256444-grw5s2pf	245	30	cleaved	cleave	VBN
cord-256444-grw5s2pf	245	31	and	and	CC
cord-256444-grw5s2pf	245	32	lacks	lack	VBZ
cord-256444-grw5s2pf	245	33	most	most	JJS
cord-256444-grw5s2pf	245	34	of	of	IN
cord-256444-grw5s2pf	245	35	the	the	DT
cord-256444-grw5s2pf	245	36	C	C	NNP
cord-256444-grw5s2pf	245	37	-	-	HYPH
cord-256444-grw5s2pf	245	38	terminal	terminal	NN
cord-256444-grw5s2pf	245	39	subunit	subunit	NN
cord-256444-grw5s2pf	245	40	of	of	IN
cord-256444-grw5s2pf	245	41	the	the	DT
cord-256444-grw5s2pf	245	42	HEF	HEF	NNP
cord-256444-grw5s2pf	245	43	of	of	IN
cord-256444-grw5s2pf	245	44	influenza	influenza	NN
cord-256444-grw5s2pf	245	45	C	C	NNP
cord-256444-grw5s2pf	245	46	virus	virus	NN
cord-256444-grw5s2pf	245	47	.	.	.
cord-256444-grw5s2pf	246	1	Because	because	IN
cord-256444-grw5s2pf	246	2	of	of	IN
cord-256444-grw5s2pf	246	3	the	the	DT
cord-256444-grw5s2pf	246	4	close	close	JJ
cord-256444-grw5s2pf	246	5	relatedness	relatedness	NN
cord-256444-grw5s2pf	246	6	between	between	IN
cord-256444-grw5s2pf	246	7	the	the	DT
cord-256444-grw5s2pf	246	8	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	246	9	HE	he	PRP
cord-256444-grw5s2pf	246	10	protein	protein	NN
cord-256444-grw5s2pf	246	11	and	and	CC
cord-256444-grw5s2pf	246	12	the	the	DT
cord-256444-grw5s2pf	246	13	influenza	influenza	NN
cord-256444-grw5s2pf	246	14	C	C	NNP
cord-256444-grw5s2pf	246	15	virus	virus	NN
cord-256444-grw5s2pf	246	16	HEF	HEF	NNP
cord-256444-grw5s2pf	246	17	protein	protein	NN
cord-256444-grw5s2pf	246	18	,	,	,
cord-256444-grw5s2pf	246	19	and	and	CC
cord-256444-grw5s2pf	246	20	because	because	IN
cord-256444-grw5s2pf	246	21	the	the	DT
cord-256444-grw5s2pf	246	22	HE	HE	NNP
cord-256444-grw5s2pf	246	23	gene	gene	NN
cord-256444-grw5s2pf	246	24	is	be	VBZ
cord-256444-grw5s2pf	246	25	present	present	JJ
cord-256444-grw5s2pf	246	26	in	in	IN
cord-256444-grw5s2pf	246	27	only	only	RB
cord-256444-grw5s2pf	246	28	one	one	CD
cord-256444-grw5s2pf	246	29	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	246	30	group	group	NN
cord-256444-grw5s2pf	246	31	,	,	,
cord-256444-grw5s2pf	246	32	it	-PRON-	PRP
cord-256444-grw5s2pf	246	33	was	be	VBD
cord-256444-grw5s2pf	246	34	proposed	propose	VBN
cord-256444-grw5s2pf	246	35	that	that	IN
cord-256444-grw5s2pf	246	36	the	the	DT
cord-256444-grw5s2pf	246	37	HE	HE	NNP
cord-256444-grw5s2pf	246	38	gene	gene	NN
cord-256444-grw5s2pf	246	39	was	be	VBD
cord-256444-grw5s2pf	246	40	acquired	acquire	VBN
cord-256444-grw5s2pf	246	41	by	by	IN
cord-256444-grw5s2pf	246	42	a	a	DT
cord-256444-grw5s2pf	246	43	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	246	44	as	as	IN
cord-256444-grw5s2pf	246	45	a	a	DT
cord-256444-grw5s2pf	246	46	result	result	NN
cord-256444-grw5s2pf	246	47	of	of	IN
cord-256444-grw5s2pf	246	48	recombination	recombination	NN
cord-256444-grw5s2pf	246	49	between	between	IN
cord-256444-grw5s2pf	246	50	an	an	DT
cord-256444-grw5s2pf	246	51	ancestral	ancestral	JJ
cord-256444-grw5s2pf	246	52	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	246	53	and	and	CC
cord-256444-grw5s2pf	246	54	influenza	influenza	NN
cord-256444-grw5s2pf	246	55	C	c	NN
cord-256444-grw5s2pf	246	56	virus	virus	NN
cord-256444-grw5s2pf	246	57	(	(	-LRB-
cord-256444-grw5s2pf	246	58	Luytjes	Luytjes	NNP
cord-256444-grw5s2pf	246	59	et	et	NNP
cord-256444-grw5s2pf	246	60	al	al	NNP
cord-256444-grw5s2pf	246	61	.	.	NNP
cord-256444-grw5s2pf	246	62	,	,	,
cord-256444-grw5s2pf	246	63	1988	1988	CD
cord-256444-grw5s2pf	246	64	)	)	-RRB-
cord-256444-grw5s2pf	246	65	.	.	.
cord-256444-grw5s2pf	247	1	Interestingly	interestingly	RB
cord-256444-grw5s2pf	247	2	,	,	,
cord-256444-grw5s2pf	247	3	the	the	DT
cord-256444-grw5s2pf	247	4	torovirus	torovirus	NNP
cord-256444-grw5s2pf	247	5	Berne	Berne	NNP
cord-256444-grw5s2pf	247	6	virus	virus	NN
cord-256444-grw5s2pf	247	7	also	also	RB
cord-256444-grw5s2pf	247	8	has	have	VBZ
cord-256444-grw5s2pf	247	9	an	an	DT
cord-256444-grw5s2pf	247	10	HE	HE	NNP
cord-256444-grw5s2pf	247	11	pseudogene	pseudogene	NN
cord-256444-grw5s2pf	247	12	(	(	-LRB-
cord-256444-grw5s2pf	247	13	gene	gene	NN
cord-256444-grw5s2pf	247	14	4	4	CD
cord-256444-grw5s2pf	247	15	;	;	:
cord-256444-grw5s2pf	247	16	Fig	Fig	NNP
cord-256444-grw5s2pf	247	17	.	.	NNP
cord-256444-grw5s2pf	247	18	2	2	CD
cord-256444-grw5s2pf	247	19	)	)	-RRB-
cord-256444-grw5s2pf	248	1	(	(	-LRB-
cord-256444-grw5s2pf	248	2	Snijder	Snijder	NNP
cord-256444-grw5s2pf	248	3	and	and	CC
cord-256444-grw5s2pf	248	4	Horzinek	Horzinek	NNPS
cord-256444-grw5s2pf	248	5	,	,	,
cord-256444-grw5s2pf	248	6	1995	1995	CD
cord-256444-grw5s2pf	248	7	)	)	-RRB-
cord-256444-grw5s2pf	248	8	,	,	,
cord-256444-grw5s2pf	248	9	the	the	DT
cord-256444-grw5s2pf	248	10	amino	amino	NN
cord-256444-grw5s2pf	248	11	acid	acid	NN
cord-256444-grw5s2pf	248	12	sequence	sequence	NN
cord-256444-grw5s2pf	248	13	of	of	IN
cord-256444-grw5s2pf	248	14	which	which	WDT
cord-256444-grw5s2pf	248	15	has	have	VBZ
cord-256444-grw5s2pf	248	16	approximately	approximately	RB
cord-256444-grw5s2pf	248	17	30	30	CD
cord-256444-grw5s2pf	248	18	%	%	NN
cord-256444-grw5s2pf	248	19	identity	identity	NN
cord-256444-grw5s2pf	248	20	with	with	IN
cord-256444-grw5s2pf	248	21	the	the	DT
cord-256444-grw5s2pf	248	22	C	C	NNP
cord-256444-grw5s2pf	248	23	-	-	HYPH
cord-256444-grw5s2pf	248	24	terminal	terminal	NN
cord-256444-grw5s2pf	248	25	part	part	NN
cord-256444-grw5s2pf	248	26	of	of	IN
cord-256444-grw5s2pf	248	27	the	the	DT
cord-256444-grw5s2pf	248	28	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	248	29	HE	he	PRP
cord-256444-grw5s2pf	248	30	.	.	.
cord-256444-grw5s2pf	249	1	The	the	DT
cord-256444-grw5s2pf	249	2	functional	functional	JJ
cord-256444-grw5s2pf	249	3	significance	significance	NN
cord-256444-grw5s2pf	249	4	of	of	IN
cord-256444-grw5s2pf	249	5	HE	he	PRP
cord-256444-grw5s2pf	249	6	for	for	IN
cord-256444-grw5s2pf	249	7	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	249	8	is	be	VBZ
cord-256444-grw5s2pf	249	9	not	not	RB
cord-256444-grw5s2pf	249	10	known	know	VBN
cord-256444-grw5s2pf	249	11	.	.	.
cord-256444-grw5s2pf	250	1	Among	among	IN
cord-256444-grw5s2pf	250	2	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	250	3	,	,	,
cord-256444-grw5s2pf	250	4	only	only	RB
cord-256444-grw5s2pf	250	5	BCV	BCV	NNP
cord-256444-grw5s2pf	250	6	requires	require	VBZ
cord-256444-grw5s2pf	250	7	HE	he	PRP
cord-256444-grw5s2pf	250	8	for	for	IN
cord-256444-grw5s2pf	250	9	infectivity	infectivity	NN
cord-256444-grw5s2pf	250	10	;	;	:
cord-256444-grw5s2pf	250	11	however	however	RB
cord-256444-grw5s2pf	250	12	,	,	,
cord-256444-grw5s2pf	250	13	the	the	DT
cord-256444-grw5s2pf	250	14	presence	presence	NN
cord-256444-grw5s2pf	250	15	of	of	IN
cord-256444-grw5s2pf	250	16	HE	he	PRP
cord-256444-grw5s2pf	250	17	may	may	MD
cord-256444-grw5s2pf	250	18	affect	affect	VB
cord-256444-grw5s2pf	250	19	the	the	DT
cord-256444-grw5s2pf	250	20	pathogenicity	pathogenicity	NN
cord-256444-grw5s2pf	250	21	of	of	IN
cord-256444-grw5s2pf	250	22	some	some	DT
cord-256444-grw5s2pf	250	23	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	250	24	,	,	,
cord-256444-grw5s2pf	250	25	as	as	IN
cord-256444-grw5s2pf	250	26	evidenced	evidence	VBN
cord-256444-grw5s2pf	250	27	by	by	IN
cord-256444-grw5s2pf	250	28	the	the	DT
cord-256444-grw5s2pf	250	29	findings	finding	NNS
cord-256444-grw5s2pf	250	30	that	that	WDT
cord-256444-grw5s2pf	250	31	passive	passive	JJ
cord-256444-grw5s2pf	250	32	administration	administration	NN
cord-256444-grw5s2pf	250	33	of	of	IN
cord-256444-grw5s2pf	250	34	HE	HE	NNP
cord-256444-grw5s2pf	250	35	-	-	HYPH
cord-256444-grw5s2pf	250	36	specific	specific	JJ
cord-256444-grw5s2pf	250	37	MAb	MAb	NNS
cord-256444-grw5s2pf	250	38	in	in	IN
cord-256444-grw5s2pf	250	39	mice	mouse	NNS
cord-256444-grw5s2pf	250	40	altered	alter	VBD
cord-256444-grw5s2pf	250	41	MHV	MHV	NNP
cord-256444-grw5s2pf	250	42	pathogenicity	pathogenicity	NN
cord-256444-grw5s2pf	250	43	and	and	CC
cord-256444-grw5s2pf	250	44	that	that	IN
cord-256444-grw5s2pf	250	45	MHVs	MHVs	NNP
cord-256444-grw5s2pf	250	46	with	with	IN
cord-256444-grw5s2pf	250	47	an	an	DT
cord-256444-grw5s2pf	250	48	HE	he	PRP
cord-256444-grw5s2pf	250	49	have	have	VB
cord-256444-grw5s2pf	250	50	different	different	JJ
cord-256444-grw5s2pf	250	51	neuropathogenicity	neuropathogenicity	NN
cord-256444-grw5s2pf	250	52	from	from	IN
cord-256444-grw5s2pf	250	53	those	those	DT
cord-256444-grw5s2pf	250	54	without	without	IN
cord-256444-grw5s2pf	250	55	HE	he	PRP
cord-256444-grw5s2pf	250	56	.	.	.
cord-256444-grw5s2pf	251	1	Conceivably	conceivably	RB
cord-256444-grw5s2pf	251	2	,	,	,
cord-256444-grw5s2pf	251	3	the	the	DT
cord-256444-grw5s2pf	251	4	presence	presence	NN
cord-256444-grw5s2pf	251	5	of	of	IN
cord-256444-grw5s2pf	251	6	HE	he	PRP
cord-256444-grw5s2pf	251	7	in	in	IN
cord-256444-grw5s2pf	251	8	an	an	DT
cord-256444-grw5s2pf	251	9	MHV	MHV	NNP
cord-256444-grw5s2pf	251	10	may	may	MD
cord-256444-grw5s2pf	251	11	allow	allow	VB
cord-256444-grw5s2pf	251	12	the	the	DT
cord-256444-grw5s2pf	251	13	virus	virus	NN
cord-256444-grw5s2pf	251	14	to	to	TO
cord-256444-grw5s2pf	251	15	utilize	utilize	VB
cord-256444-grw5s2pf	251	16	an	an	DT
cord-256444-grw5s2pf	251	17	alternative	alternative	JJ
cord-256444-grw5s2pf	251	18	receptor	receptor	NN
cord-256444-grw5s2pf	251	19	independently	independently	RB
cord-256444-grw5s2pf	251	20	of	of	IN
cord-256444-grw5s2pf	251	21	the	the	DT
cord-256444-grw5s2pf	251	22	S	S	NNP
cord-256444-grw5s2pf	251	23	protein	protein	NN
cord-256444-grw5s2pf	251	24	.	.	.
cord-256444-grw5s2pf	252	1	However	however	RB
cord-256444-grw5s2pf	252	2	,	,	,
cord-256444-grw5s2pf	252	3	this	this	DT
cord-256444-grw5s2pf	252	4	is	be	VBZ
cord-256444-grw5s2pf	252	5	not	not	RB
cord-256444-grw5s2pf	252	6	the	the	DT
cord-256444-grw5s2pf	252	7	case	case	NN
cord-256444-grw5s2pf	252	8	,	,	,
cord-256444-grw5s2pf	252	9	as	as	IN
cord-256444-grw5s2pf	252	10	evidenced	evidence	VBN
cord-256444-grw5s2pf	252	11	by	by	IN
cord-256444-grw5s2pf	252	12	the	the	DT
cord-256444-grw5s2pf	252	13	finding	finding	NN
cord-256444-grw5s2pf	252	14	that	that	IN
cord-256444-grw5s2pf	252	15	an	an	DT
cord-256444-grw5s2pf	252	16	MAb	MAb	NNS
cord-256444-grw5s2pf	252	17	specific	specific	JJ
cord-256444-grw5s2pf	252	18	for	for	IN
cord-256444-grw5s2pf	252	19	the	the	DT
cord-256444-grw5s2pf	252	20	murine	murine	JJ
cord-256444-grw5s2pf	252	21	biliary	biliary	JJ
cord-256444-grw5s2pf	252	22	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	252	23	molecule	molecule	NN
cord-256444-grw5s2pf	252	24	,	,	,
cord-256444-grw5s2pf	252	25	which	which	WDT
cord-256444-grw5s2pf	252	26	is	be	VBZ
cord-256444-grw5s2pf	252	27	the	the	DT
cord-256444-grw5s2pf	252	28	major	major	JJ
cord-256444-grw5s2pf	252	29	MHV	MHV	NNP
cord-256444-grw5s2pf	252	30	receptor	receptor	NN
cord-256444-grw5s2pf	252	31	recognized	recognize	VBN
cord-256444-grw5s2pf	252	32	by	by	IN
cord-256444-grw5s2pf	252	33	S	S	NNP
cord-256444-grw5s2pf	252	34	,	,	,
cord-256444-grw5s2pf	252	35	inhibited	inhibit	VBD
cord-256444-grw5s2pf	252	36	the	the	DT
cord-256444-grw5s2pf	252	37	infectivity	infectivity	NN
cord-256444-grw5s2pf	252	38	of	of	IN
cord-256444-grw5s2pf	252	39	an	an	DT
cord-256444-grw5s2pf	252	40	HE	HE	NNP
cord-256444-grw5s2pf	252	41	-	-	HYPH
cord-256444-grw5s2pf	252	42	containing	contain	VBG
cord-256444-grw5s2pf	252	43	MHV	MHV	NNP
cord-256444-grw5s2pf	252	44	(	(	-LRB-
cord-256444-grw5s2pf	252	45	Gagneten	Gagneten	NNP
cord-256444-grw5s2pf	252	46	et	et	FW
cord-256444-grw5s2pf	252	47	al	al	NNP
cord-256444-grw5s2pf	252	48	.	.	NNP
cord-256444-grw5s2pf	252	49	,	,	,
cord-256444-grw5s2pf	252	50	1995	1995	CD
cord-256444-grw5s2pf	252	51	)	)	-RRB-
cord-256444-grw5s2pf	252	52	.	.	.
cord-256444-grw5s2pf	253	1	Thus	thus	RB
cord-256444-grw5s2pf	253	2	,	,	,
cord-256444-grw5s2pf	253	3	the	the	DT
cord-256444-grw5s2pf	253	4	HE	HE	NNP
cord-256444-grw5s2pf	253	5	protein	protein	NN
cord-256444-grw5s2pf	253	6	does	do	VBZ
cord-256444-grw5s2pf	253	7	not	not	RB
cord-256444-grw5s2pf	253	8	enable	enable	VB
cord-256444-grw5s2pf	253	9	a	a	DT
cord-256444-grw5s2pf	253	10	virus	virus	NN
cord-256444-grw5s2pf	253	11	to	to	TO
cord-256444-grw5s2pf	253	12	bypass	bypass	VB
cord-256444-grw5s2pf	253	13	the	the	DT
cord-256444-grw5s2pf	253	14	primary	primary	JJ
cord-256444-grw5s2pf	253	15	MHV	MHV	NNP
cord-256444-grw5s2pf	253	16	receptor	receptor	NN
cord-256444-grw5s2pf	253	17	and	and	CC
cord-256444-grw5s2pf	253	18	may	may	MD
cord-256444-grw5s2pf	253	19	provide	provide	VB
cord-256444-grw5s2pf	253	20	only	only	RB
cord-256444-grw5s2pf	253	21	an	an	DT
cord-256444-grw5s2pf	253	22	auxiliary	auxiliary	JJ
cord-256444-grw5s2pf	253	23	function	function	NN
cord-256444-grw5s2pf	253	24	for	for	IN
cord-256444-grw5s2pf	253	25	virus	virus	NN
cord-256444-grw5s2pf	253	26	binding	bind	VBG
cord-256444-grw5s2pf	253	27	to	to	TO
cord-256444-grw5s2pf	253	28	target	target	VB
cord-256444-grw5s2pf	253	29	cells	cell	NNS
cord-256444-grw5s2pf	253	30	.	.	.
cord-256444-grw5s2pf	254	1	Until	until	IN
cord-256444-grw5s2pf	254	2	recently	recently	RB
cord-256444-grw5s2pf	254	3	it	-PRON-	PRP
cord-256444-grw5s2pf	254	4	was	be	VBD
cord-256444-grw5s2pf	254	5	thought	think	VBN
cord-256444-grw5s2pf	254	6	that	that	IN
cord-256444-grw5s2pf	254	7	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	254	8	possessed	possess	VBD
cord-256444-grw5s2pf	254	9	three	three	CD
cord-256444-grw5s2pf	254	10	(	(	-LRB-
cord-256444-grw5s2pf	254	11	S	S	NNP
cord-256444-grw5s2pf	254	12	,	,	,
cord-256444-grw5s2pf	254	13	N	N	NNP
cord-256444-grw5s2pf	254	14	,	,	,
cord-256444-grw5s2pf	254	15	M	M	NNP
cord-256444-grw5s2pf	254	16	)	)	-RRB-
cord-256444-grw5s2pf	254	17	or	or	CC
cord-256444-grw5s2pf	254	18	four	four	CD
cord-256444-grw5s2pf	254	19	(	(	-LRB-
cord-256444-grw5s2pf	254	20	including	include	VBG
cord-256444-grw5s2pf	254	21	HE	HE	NNP
cord-256444-grw5s2pf	254	22	)	)	-RRB-
cord-256444-grw5s2pf	254	23	structural	structural	JJ
cord-256444-grw5s2pf	254	24	proteins	protein	NNS
cord-256444-grw5s2pf	254	25	.	.	.
cord-256444-grw5s2pf	255	1	It	-PRON-	PRP
cord-256444-grw5s2pf	255	2	is	be	VBZ
cord-256444-grw5s2pf	255	3	now	now	RB
cord-256444-grw5s2pf	255	4	clear	clear	JJ
cord-256444-grw5s2pf	255	5	that	that	IN
cord-256444-grw5s2pf	255	6	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	255	7	,	,	,
cord-256444-grw5s2pf	255	8	but	but	CC
cord-256444-grw5s2pf	255	9	not	not	RB
cord-256444-grw5s2pf	255	10	toroviruses	toroviruses	NNP
cord-256444-grw5s2pf	255	11	,	,	,
cord-256444-grw5s2pf	255	12	possess	possess	VBP
cord-256444-grw5s2pf	255	13	an	an	DT
cord-256444-grw5s2pf	255	14	additional	additional	JJ
cord-256444-grw5s2pf	255	15	virion	virion	NN
cord-256444-grw5s2pf	255	16	protein	protein	NN
cord-256444-grw5s2pf	255	17	,	,	,
cord-256444-grw5s2pf	255	18	the	the	DT
cord-256444-grw5s2pf	255	19	E	e	NN
cord-256444-grw5s2pf	255	20	protein	protein	NN
cord-256444-grw5s2pf	255	21	.	.	.
cord-256444-grw5s2pf	256	1	It	-PRON-	PRP
cord-256444-grw5s2pf	256	2	plays	play	VBZ
cord-256444-grw5s2pf	256	3	an	an	DT
cord-256444-grw5s2pf	256	4	essential	essential	JJ
cord-256444-grw5s2pf	256	5	role	role	NN
cord-256444-grw5s2pf	256	6	in	in	IN
cord-256444-grw5s2pf	256	7	virion	virion	NN
cord-256444-grw5s2pf	256	8	assembly	assembly	NN
cord-256444-grw5s2pf	256	9	.	.	.
cord-256444-grw5s2pf	257	1	It	-PRON-	PRP
cord-256444-grw5s2pf	257	2	has	have	VBZ
cord-256444-grw5s2pf	257	3	been	be	VBN
cord-256444-grw5s2pf	257	4	shown	show	VBN
cord-256444-grw5s2pf	257	5	that	that	IN
cord-256444-grw5s2pf	257	6	the	the	DT
cord-256444-grw5s2pf	257	7	E	E	NNP
cord-256444-grw5s2pf	257	8	and	and	CC
cord-256444-grw5s2pf	257	9	M	M	NNP
cord-256444-grw5s2pf	257	10	proteins	protein	NNS
cord-256444-grw5s2pf	257	11	are	be	VBP
cord-256444-grw5s2pf	257	12	the	the	DT
cord-256444-grw5s2pf	257	13	only	only	JJ
cord-256444-grw5s2pf	257	14	two	two	CD
cord-256444-grw5s2pf	257	15	viral	viral	JJ
cord-256444-grw5s2pf	257	16	proteins	protein	NNS
cord-256444-grw5s2pf	257	17	absolutely	absolutely	RB
cord-256444-grw5s2pf	257	18	required	require	VBN
cord-256444-grw5s2pf	257	19	for	for	IN
cord-256444-grw5s2pf	257	20	virion	virion	NN
cord-256444-grw5s2pf	257	21	assembly	assembly	NN
cord-256444-grw5s2pf	257	22	(	(	-LRB-
cord-256444-grw5s2pf	257	23	Bos	Bos	NNP
cord-256444-grw5s2pf	257	24	et	et	NNP
cord-256444-grw5s2pf	257	25	al	al	NNP
cord-256444-grw5s2pf	257	26	.	.	NNP
cord-256444-grw5s2pf	257	27	,	,	,
cord-256444-grw5s2pf	257	28	1996	1996	CD
cord-256444-grw5s2pf	257	29	;	;	:
cord-256444-grw5s2pf	257	30	Vennema	Vennema	NNP
cord-256444-grw5s2pf	257	31	et	et	FW
cord-256444-grw5s2pf	257	32	al	al	NNP
cord-256444-grw5s2pf	257	33	.	.	NNP
cord-256444-grw5s2pf	257	34	,	,	,
cord-256444-grw5s2pf	257	35	1996	1996	CD
cord-256444-grw5s2pf	257	36	)	)	-RRB-
cord-256444-grw5s2pf	257	37	.	.	.
cord-256444-grw5s2pf	258	1	This	this	DT
cord-256444-grw5s2pf	258	2	protein	protein	NN
cord-256444-grw5s2pf	258	3	has	have	VBZ
cord-256444-grw5s2pf	258	4	been	be	VBN
cord-256444-grw5s2pf	258	5	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	258	6	for	for	IN
cord-256444-grw5s2pf	258	7	IBV	IBV	NNP
cord-256444-grw5s2pf	258	8	(	(	-LRB-
cord-256444-grw5s2pf	258	9	Smith	Smith	NNP
cord-256444-grw5s2pf	258	10	et	et	NNP
cord-256444-grw5s2pf	258	11	al	al	NNP
cord-256444-grw5s2pf	258	12	.	.	NNP
cord-256444-grw5s2pf	258	13	,	,	,
cord-256444-grw5s2pf	258	14	1990	1990	CD
cord-256444-grw5s2pf	258	15	;	;	:
cord-256444-grw5s2pf	258	16	Liu	Liu	NNP
cord-256444-grw5s2pf	258	17	et	et	NNP
cord-256444-grw5s2pf	258	18	al	al	NNP
cord-256444-grw5s2pf	258	19	.	.	.
cord-256444-grw5s2pf	259	1	,	,	,
cord-256444-grw5s2pf	259	2	19911	19911	CD
cord-256444-grw5s2pf	259	3	,	,	,
cord-256444-grw5s2pf	259	4	TGEV	TGEV	NNP
cord-256444-grw5s2pf	259	5	(	(	-LRB-
cord-256444-grw5s2pf	259	6	Godet	Godet	NNP
cord-256444-grw5s2pf	259	7	et	et	NNP
cord-256444-grw5s2pf	259	8	al	al	NNP
cord-256444-grw5s2pf	259	9	.	.	NNP
cord-256444-grw5s2pf	259	10	,	,	,
cord-256444-grw5s2pf	259	11	1992	1992	CD
cord-256444-grw5s2pf	259	12	)	)	-RRB-
cord-256444-grw5s2pf	259	13	and	and	CC
cord-256444-grw5s2pf	259	14	MHV	MHV	NNP
cord-256444-grw5s2pf	259	15	(	(	-LRB-
cord-256444-grw5s2pf	259	16	Yu	Yu	NNP
cord-256444-grw5s2pf	259	17	et	et	FW
cord-256444-grw5s2pf	259	18	al	al	NNP
cord-256444-grw5s2pf	259	19	.	.	NNP
cord-256444-grw5s2pf	259	20	,	,	,
cord-256444-grw5s2pf	259	21	1994	1994	CD
cord-256444-grw5s2pf	259	22	)	)	-RRB-
cord-256444-grw5s2pf	259	23	.	.	.
cord-256444-grw5s2pf	260	1	When	when	WRB
cord-256444-grw5s2pf	260	2	the	the	DT
cord-256444-grw5s2pf	260	3	deduced	deduce	VBN
cord-256444-grw5s2pf	260	4	E	e	NN
cord-256444-grw5s2pf	260	5	proteins	protein	NNS
cord-256444-grw5s2pf	260	6	of	of	IN
cord-256444-grw5s2pf	260	7	the	the	DT
cord-256444-grw5s2pf	260	8	other	other	JJ
cord-256444-grw5s2pf	260	9	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	260	10	are	be	VBP
cord-256444-grw5s2pf	260	11	taken	take	VBN
cord-256444-grw5s2pf	260	12	into	into	IN
cord-256444-grw5s2pf	260	13	account	account	NN
cord-256444-grw5s2pf	260	14	,	,	,
cord-256444-grw5s2pf	260	15	it	-PRON-	PRP
cord-256444-grw5s2pf	260	16	transpires	transpire	VBZ
cord-256444-grw5s2pf	260	17	that	that	IN
cord-256444-grw5s2pf	260	18	the	the	DT
cord-256444-grw5s2pf	260	19	E	e	NN
cord-256444-grw5s2pf	260	20	proteins	protein	NNS
cord-256444-grw5s2pf	260	21	vary	vary	VBP
cord-256444-grw5s2pf	260	22	from	from	IN
cord-256444-grw5s2pf	260	23	84	84	CD
cord-256444-grw5s2pf	260	24	t	t	NN
cord-256444-grw5s2pf	260	25	o	o	NN
cord-256444-grw5s2pf	260	26	109	109	CD
cord-256444-grw5s2pf	260	27	amino	amino	JJ
cord-256444-grw5s2pf	260	28	acids	acid	NNS
cord-256444-grw5s2pf	260	29	,	,	,
cord-256444-grw5s2pf	260	30	corresponding	correspond	VBG
cord-256444-grw5s2pf	260	31	to	to	IN
cord-256444-grw5s2pf	260	32	molecular	molecular	JJ
cord-256444-grw5s2pf	260	33	weights	weight	NNS
cord-256444-grw5s2pf	260	34	of	of	IN
cord-256444-grw5s2pf	260	35	9100	9100	CD
cord-256444-grw5s2pf	260	36	to	to	IN
cord-256444-grw5s2pf	260	37	12,400	12,400	CD
cord-256444-grw5s2pf	261	1	(	(	-LRB-
cord-256444-grw5s2pf	261	2	Siddell	Siddell	NNP
cord-256444-grw5s2pf	261	3	,	,	,
cord-256444-grw5s2pf	261	4	1995~	1995~	CD
cord-256444-grw5s2pf	261	5	)	)	-RRB-
cord-256444-grw5s2pf	261	6	.	.	.
cord-256444-grw5s2pf	262	1	Siddell	Siddell	NNP
cord-256444-grw5s2pf	262	2	has	have	VBZ
cord-256444-grw5s2pf	262	3	highlighted	highlight	VBN
cord-256444-grw5s2pf	262	4	a	a	DT
cord-256444-grw5s2pf	262	5	number	number	NN
cord-256444-grw5s2pf	262	6	of	of	IN
cord-256444-grw5s2pf	262	7	features	feature	NNS
cord-256444-grw5s2pf	262	8	common	common	JJ
cord-256444-grw5s2pf	262	9	to	to	IN
cord-256444-grw5s2pf	262	10	all	all	PDT
cord-256444-grw5s2pf	262	11	the	the	DT
cord-256444-grw5s2pf	262	12	E	e	NN
cord-256444-grw5s2pf	262	13	proteins	protein	NNS
cord-256444-grw5s2pf	262	14	,	,	,
cord-256444-grw5s2pf	262	15	namely	namely	RB
cord-256444-grw5s2pf	262	16	,	,	,
cord-256444-grw5s2pf	262	17	a	a	DT
cord-256444-grw5s2pf	262	18	hydrophobic	hydrophobic	JJ
cord-256444-grw5s2pf	262	19	region	region	NN
cord-256444-grw5s2pf	262	20	of	of	IN
cord-256444-grw5s2pf	262	21	some	some	DT
cord-256444-grw5s2pf	262	22	two	two	CD
cord-256444-grw5s2pf	262	23	dozen	dozen	NN
cord-256444-grw5s2pf	262	24	residues	residue	NNS
cord-256444-grw5s2pf	262	25	,	,	,
cord-256444-grw5s2pf	262	26	starting	start	VBG
cord-256444-grw5s2pf	262	27	near	near	IN
cord-256444-grw5s2pf	262	28	the	the	DT
cord-256444-grw5s2pf	262	29	N	n	CD
cord-256444-grw5s2pf	262	30	terminus	terminus	NN
cord-256444-grw5s2pf	262	31	;	;	:
cord-256444-grw5s2pf	262	32	a	a	DT
cord-256444-grw5s2pf	262	33	cysteine	cysteine	NN
cord-256444-grw5s2pf	262	34	-	-	HYPH
cord-256444-grw5s2pf	262	35	rich	rich	JJ
cord-256444-grw5s2pf	262	36	region	region	NN
cord-256444-grw5s2pf	262	37	immediately	immediately	RB
cord-256444-grw5s2pf	262	38	downstream	downstream	RB
cord-256444-grw5s2pf	262	39	from	from	IN
cord-256444-grw5s2pf	262	40	this	this	DT
cord-256444-grw5s2pf	262	41	;	;	:
cord-256444-grw5s2pf	262	42	a	a	DT
cord-256444-grw5s2pf	262	43	conserved	conserve	VBN
cord-256444-grw5s2pf	262	44	proline	proline	NN
cord-256444-grw5s2pf	262	45	residue	residue	NN
cord-256444-grw5s2pf	262	46	in	in	IN
cord-256444-grw5s2pf	262	47	the	the	DT
cord-256444-grw5s2pf	262	48	middle	middle	NN
cord-256444-grw5s2pf	262	49	of	of	IN
cord-256444-grw5s2pf	262	50	the	the	DT
cord-256444-grw5s2pf	262	51	molecule	molecule	NN
cord-256444-grw5s2pf	262	52	,	,	,
cord-256444-grw5s2pf	262	53	and	and	CC
cord-256444-grw5s2pf	262	54	otherwise	otherwise	RB
cord-256444-grw5s2pf	262	55	very	very	RB
cord-256444-grw5s2pf	262	56	low	low	JJ
cord-256444-grw5s2pf	262	57	amino	amino	NN
cord-256444-grw5s2pf	262	58	acid	acid	NN
cord-256444-grw5s2pf	262	59	identity	identity	NN
cord-256444-grw5s2pf	262	60	in	in	IN
cord-256444-grw5s2pf	262	61	the	the	DT
cord-256444-grw5s2pf	262	62	genus	genus	NN
cord-256444-grw5s2pf	262	63	as	as	IN
cord-256444-grw5s2pf	262	64	a	a	DT
cord-256444-grw5s2pf	262	65	whole	whole	NN
cord-256444-grw5s2pf	262	66	;	;	:
cord-256444-grw5s2pf	262	67	and	and	CC
cord-256444-grw5s2pf	262	68	an	an	DT
cord-256444-grw5s2pf	262	69	abundance	abundance	NN
cord-256444-grw5s2pf	262	70	of	of	IN
cord-256444-grw5s2pf	262	71	charged	charge	VBN
cord-256444-grw5s2pf	262	72	residues	residue	NNS
cord-256444-grw5s2pf	262	73	in	in	IN
cord-256444-grw5s2pf	262	74	the	the	DT
cord-256444-grw5s2pf	262	75	Cterminal	Cterminal	NNP
cord-256444-grw5s2pf	262	76	half	half	NN
cord-256444-grw5s2pf	262	77	of	of	IN
cord-256444-grw5s2pf	262	78	the	the	DT
cord-256444-grw5s2pf	262	79	protein	protein	NN
cord-256444-grw5s2pf	262	80	(	(	-LRB-
cord-256444-grw5s2pf	262	81	Siddell	Siddell	NNP
cord-256444-grw5s2pf	262	82	,	,	,
cord-256444-grw5s2pf	262	83	1995~	1995~	CD
cord-256444-grw5s2pf	262	84	)	)	-RRB-
cord-256444-grw5s2pf	262	85	.	.	.
cord-256444-grw5s2pf	263	1	It	-PRON-	PRP
cord-256444-grw5s2pf	263	2	is	be	VBZ
cord-256444-grw5s2pf	263	3	now	now	RB
cord-256444-grw5s2pf	263	4	well	well	RB
cord-256444-grw5s2pf	263	5	established	establish	VBN
cord-256444-grw5s2pf	263	6	that	that	IN
cord-256444-grw5s2pf	263	7	this	this	DT
cord-256444-grw5s2pf	263	8	protein	protein	NN
cord-256444-grw5s2pf	263	9	is	be	VBZ
cord-256444-grw5s2pf	263	10	associated	associate	VBN
cord-256444-grw5s2pf	263	11	with	with	IN
cord-256444-grw5s2pf	263	12	highly	highly	RB
cord-256444-grw5s2pf	263	13	purified	purify	VBN
cord-256444-grw5s2pf	263	14	virion	virion	NN
cord-256444-grw5s2pf	263	15	preparations	preparation	NNS
cord-256444-grw5s2pf	263	16	(	(	-LRB-
cord-256444-grw5s2pf	264	1	Liu	Liu	NNP
cord-256444-grw5s2pf	264	2	et	et	NNP
cord-256444-grw5s2pf	264	3	al	al	NNP
cord-256444-grw5s2pf	264	4	.	.	.
cord-256444-grw5s2pf	265	1	,	,	,
cord-256444-grw5s2pf	265	2	1991	1991	CD
cord-256444-grw5s2pf	265	3	;	;	:
cord-256444-grw5s2pf	265	4	Godet	Godet	NNP
cord-256444-grw5s2pf	265	5	et	et	NNP
cord-256444-grw5s2pf	265	6	al	al	NNP
cord-256444-grw5s2pf	265	7	.	.	.
cord-256444-grw5s2pf	266	1	,	,	,
cord-256444-grw5s2pf	266	2	1992	1992	CD
cord-256444-grw5s2pf	266	3	;	;	:
cord-256444-grw5s2pf	266	4	Yu	Yu	NNP
cord-256444-grw5s2pf	266	5	et	et	NNP
cord-256444-grw5s2pf	266	6	al	al	NNP
cord-256444-grw5s2pf	266	7	.	.	NNP
cord-256444-grw5s2pf	266	8	,	,	,
cord-256444-grw5s2pf	266	9	1994	1994	CD
cord-256444-grw5s2pf	266	10	)	)	-RRB-
cord-256444-grw5s2pf	266	11	.	.	.
cord-256444-grw5s2pf	267	1	Liu	Liu	NNP
cord-256444-grw5s2pf	267	2	and	and	CC
cord-256444-grw5s2pf	267	3	Inglis	Inglis	NNP
cord-256444-grw5s2pf	267	4	calculated	calculate	VBD
cord-256444-grw5s2pf	267	5	the	the	DT
cord-256444-grw5s2pf	267	6	ratio	ratio	NN
cord-256444-grw5s2pf	267	7	of	of	IN
cord-256444-grw5s2pf	267	8	S	s	NN
cord-256444-grw5s2pf	267	9	:	:	:
cord-256444-grw5s2pf	268	1	N	n	NN
cord-256444-grw5s2pf	268	2	:	:	:
cord-256444-grw5s2pf	268	3	M	m	NN
cord-256444-grw5s2pf	268	4	:	:	:
cord-256444-grw5s2pf	268	5	E	e	NN
cord-256444-grw5s2pf	268	6	proteins	protein	NNS
cord-256444-grw5s2pf	268	7	in	in	IN
cord-256444-grw5s2pf	268	8	virions	virion	NNS
cord-256444-grw5s2pf	268	9	of	of	IN
cord-256444-grw5s2pf	268	10	IBV	IBV	NNP
cord-256444-grw5s2pf	268	11	-	-	HYPH
cord-256444-grw5s2pf	268	12	Beaudette	Beaudette	NNP
cord-256444-grw5s2pf	268	13	strain	strain	NN
cord-256444-grw5s2pf	268	14	to	to	TO
cord-256444-grw5s2pf	268	15	be	be	VB
cord-256444-grw5s2pf	268	16	1:11:10:2	1:11:10:2	CD
cord-256444-grw5s2pf	268	17	,	,	,
cord-256444-grw5s2pf	268	18	indicating	indicate	VBG
cord-256444-grw5s2pf	268	19	an	an	DT
cord-256444-grw5s2pf	268	20	amount	amount	NN
cord-256444-grw5s2pf	268	21	of	of	IN
cord-256444-grw5s2pf	268	22	E	e	NN
cord-256444-grw5s2pf	268	23	protein	protein	NN
cord-256444-grw5s2pf	268	24	similar	similar	JJ
cord-256444-grw5s2pf	268	25	to	to	IN
cord-256444-grw5s2pf	268	26	that	that	DT
cord-256444-grw5s2pf	268	27	of	of	IN
cord-256444-grw5s2pf	268	28	S	s	NN
cord-256444-grw5s2pf	268	29	protein	protein	NN
cord-256444-grw5s2pf	268	30	(	(	-LRB-
cord-256444-grw5s2pf	268	31	Liu	Liu	NNP
cord-256444-grw5s2pf	268	32	et	et	NNP
cord-256444-grw5s2pf	268	33	al	al	NNP
cord-256444-grw5s2pf	268	34	.	.	NNP
cord-256444-grw5s2pf	268	35	,	,	,
cord-256444-grw5s2pf	268	36	1991	1991	CD
cord-256444-grw5s2pf	268	37	)	)	-RRB-
cord-256444-grw5s2pf	268	38	.	.	.
cord-256444-grw5s2pf	269	1	In	in	IN
cord-256444-grw5s2pf	269	2	contrast	contrast	NN
cord-256444-grw5s2pf	269	3	,	,	,
cord-256444-grw5s2pf	269	4	Godet	Godet	NNP
cord-256444-grw5s2pf	269	5	et	et	NNP
cord-256444-grw5s2pf	269	6	al	al	NNP
cord-256444-grw5s2pf	269	7	.	.	NNP
cord-256444-grw5s2pf	269	8	estimated	estimate	VBD
cord-256444-grw5s2pf	269	9	that	that	IN
cord-256444-grw5s2pf	269	10	the	the	DT
cord-256444-grw5s2pf	269	11	S	S	NNP
cord-256444-grw5s2pf	269	12	:	:	:
cord-256444-grw5s2pf	270	1	M	m	NN
cord-256444-grw5s2pf	270	2	:	:	:
cord-256444-grw5s2pf	270	3	E	e	NN
cord-256444-grw5s2pf	270	4	protein	protein	NN
cord-256444-grw5s2pf	270	5	ratio	ratio	NN
cord-256444-grw5s2pf	270	6	in	in	IN
cord-256444-grw5s2pf	270	7	virions	virion	NNS
cord-256444-grw5s2pf	270	8	of	of	IN
cord-256444-grw5s2pf	270	9	TGEV	TGEV	NNS
cord-256444-grw5s2pf	271	1	was	be	VBD
cord-256444-grw5s2pf	271	2	20:300:1	20:300:1	CD
cord-256444-grw5s2pf	272	1	(	(	-LRB-
cord-256444-grw5s2pf	272	2	Godet	Godet	NNP
cord-256444-grw5s2pf	272	3	et	et	NNP
cord-256444-grw5s2pf	272	4	al	al	NNP
cord-256444-grw5s2pf	272	5	.	.	NNP
cord-256444-grw5s2pf	272	6	,	,	,
cord-256444-grw5s2pf	272	7	19921	19921	CD
cord-256444-grw5s2pf	272	8	,	,	,
cord-256444-grw5s2pf	272	9	and	and	CC
cord-256444-grw5s2pf	272	10	Vennema	Vennema	NNP
cord-256444-grw5s2pf	272	11	et	et	FW
cord-256444-grw5s2pf	272	12	al	al	NNP
cord-256444-grw5s2pf	272	13	.	.	.
cord-256444-grw5s2pf	273	1	(	(	-LRB-
cord-256444-grw5s2pf	273	2	1996	1996	CD
cord-256444-grw5s2pf	273	3	)	)	-RRB-
cord-256444-grw5s2pf	273	4	have	have	VBP
cord-256444-grw5s2pf	273	5	suggested	suggest	VBN
cord-256444-grw5s2pf	273	6	an	an	DT
cord-256444-grw5s2pf	273	7	M	m	NN
cord-256444-grw5s2pf	273	8	:	:	:
cord-256444-grw5s2pf	273	9	E	e	NN
cord-256444-grw5s2pf	273	10	ratio	ratio	NN
cord-256444-grw5s2pf	273	11	of	of	IN
cord-256444-grw5s2pf	273	12	approximately	approximately	RB
cord-256444-grw5s2pf	273	13	1OO	1oo	CD
cord-256444-grw5s2pf	273	14	:	:	:
cord-256444-grw5s2pf	274	1	l	l	NNP
cord-256444-grw5s2pf	274	2	for	for	IN
cord-256444-grw5s2pf	274	3	virions	virion	NNS
cord-256444-grw5s2pf	274	4	of	of	IN
cord-256444-grw5s2pf	274	5	MHV	MHV	NNP
cord-256444-grw5s2pf	274	6	.	.	.
cord-256444-grw5s2pf	275	1	It	-PRON-	PRP
cord-256444-grw5s2pf	275	2	is	be	VBZ
cord-256444-grw5s2pf	275	3	not	not	RB
cord-256444-grw5s2pf	275	4	clear	clear	JJ
cord-256444-grw5s2pf	275	5	why	why	WRB
cord-256444-grw5s2pf	275	6	there	there	EX
cord-256444-grw5s2pf	275	7	is	be	VBZ
cord-256444-grw5s2pf	275	8	such	such	PDT
cord-256444-grw5s2pf	275	9	a	a	DT
cord-256444-grw5s2pf	275	10	wide	wide	JJ
cord-256444-grw5s2pf	275	11	range	range	NN
cord-256444-grw5s2pf	275	12	of	of	IN
cord-256444-grw5s2pf	275	13	variations	variation	NNS
cord-256444-grw5s2pf	275	14	.	.	.
cord-256444-grw5s2pf	276	1	The	the	DT
cord-256444-grw5s2pf	276	2	E	e	NN
cord-256444-grw5s2pf	276	3	protein	protein	NN
cord-256444-grw5s2pf	276	4	in	in	IN
cord-256444-grw5s2pf	276	5	the	the	DT
cord-256444-grw5s2pf	276	6	cells	cell	NNS
cord-256444-grw5s2pf	276	7	is	be	VBZ
cord-256444-grw5s2pf	276	8	localized	localize	VBN
cord-256444-grw5s2pf	276	9	in	in	IN
cord-256444-grw5s2pf	276	10	the	the	DT
cord-256444-grw5s2pf	276	11	perinuclear	perinuclear	NNP
cord-256444-grw5s2pf	276	12	region	region	NN
cord-256444-grw5s2pf	276	13	,	,	,
cord-256444-grw5s2pf	276	14	with	with	IN
cord-256444-grw5s2pf	276	15	some	some	DT
cord-256444-grw5s2pf	276	16	migrating	migrate	VBG
cord-256444-grw5s2pf	276	17	to	to	IN
cord-256444-grw5s2pf	276	18	the	the	DT
cord-256444-grw5s2pf	276	19	cell	cell	NN
cord-256444-grw5s2pf	276	20	surface	surface	NN
cord-256444-grw5s2pf	276	21	(	(	-LRB-
cord-256444-grw5s2pf	276	22	Godet	Godet	NNP
cord-256444-grw5s2pf	276	23	et	et	NNP
cord-256444-grw5s2pf	276	24	al	al	NNP
cord-256444-grw5s2pf	276	25	.	.	NNP
cord-256444-grw5s2pf	276	26	,	,	,
cord-256444-grw5s2pf	276	27	1992	1992	CD
cord-256444-grw5s2pf	276	28	;	;	:
cord-256444-grw5s2pf	276	29	Yu	Yu	NNP
cord-256444-grw5s2pf	276	30	et	et	NNP
cord-256444-grw5s2pf	276	31	aZ.	az.	FW
cord-256444-grw5s2pf	276	32	,	,	,
cord-256444-grw5s2pf	276	33	1994	1994	CD
cord-256444-grw5s2pf	276	34	)	)	-RRB-
cord-256444-grw5s2pf	276	35	.	.	.
cord-256444-grw5s2pf	277	1	Experimental	experimental	JJ
cord-256444-grw5s2pf	277	2	evidence	evidence	NN
cord-256444-grw5s2pf	277	3	suggests	suggest	VBZ
cord-256444-grw5s2pf	277	4	that	that	IN
cord-256444-grw5s2pf	277	5	the	the	DT
cord-256444-grw5s2pf	277	6	E	e	NN
cord-256444-grw5s2pf	277	7	protein	protein	NN
cord-256444-grw5s2pf	277	8	is	be	VBZ
cord-256444-grw5s2pf	277	9	anchored	anchor	VBN
cord-256444-grw5s2pf	277	10	in	in	IN
cord-256444-grw5s2pf	277	11	the	the	DT
cord-256444-grw5s2pf	277	12	membrane	membrane	NN
cord-256444-grw5s2pf	277	13	by	by	IN
cord-256444-grw5s2pf	277	14	sequence	sequence	NN
cord-256444-grw5s2pf	277	15	in	in	IN
cord-256444-grw5s2pf	277	16	the	the	DT
cord-256444-grw5s2pf	277	17	N	n	CD
cord-256444-grw5s2pf	277	18	-	-	HYPH
cord-256444-grw5s2pf	277	19	terminal	terminal	JJ
cord-256444-grw5s2pf	277	20	half	half	NN
cord-256444-grw5s2pf	277	21	of	of	IN
cord-256444-grw5s2pf	277	22	the	the	DT
cord-256444-grw5s2pf	277	23	molecule	molecule	NN
cord-256444-grw5s2pf	277	24	.	.	.
cord-256444-grw5s2pf	278	1	Thus	thus	RB
cord-256444-grw5s2pf	278	2	antibodies	antibody	NNS
cord-256444-grw5s2pf	278	3	specific	specific	JJ
cord-256444-grw5s2pf	278	4	for	for	IN
cord-256444-grw5s2pf	278	5	epitopes	epitope	NNS
cord-256444-grw5s2pf	278	6	in	in	IN
cord-256444-grw5s2pf	278	7	the	the	DT
cord-256444-grw5s2pf	278	8	C	C	NNP
cord-256444-grw5s2pf	278	9	-	-	HYPH
cord-256444-grw5s2pf	278	10	terminal	terminal	NN
cord-256444-grw5s2pf	278	11	half	half	NN
cord-256444-grw5s2pf	278	12	of	of	IN
cord-256444-grw5s2pf	278	13	the	the	DT
cord-256444-grw5s2pf	278	14	TGEV	TGEV	NNP
cord-256444-grw5s2pf	278	15	E	e	NN
cord-256444-grw5s2pf	278	16	protein	protein	NN
cord-256444-grw5s2pf	278	17	produced	produce	VBD
cord-256444-grw5s2pf	278	18	cell	cell	NN
cord-256444-grw5s2pf	278	19	-	-	HYPH
cord-256444-grw5s2pf	278	20	surface	surface	NN
cord-256444-grw5s2pf	278	21	fluorescence	fluorescence	NN
cord-256444-grw5s2pf	278	22	in	in	IN
cord-256444-grw5s2pf	278	23	paraformaldehyde	paraformaldehyde	NN
cord-256444-grw5s2pf	278	24	-	-	HYPH
cord-256444-grw5s2pf	278	25	fixed	fix	VBN
cord-256444-grw5s2pf	278	26	,	,	,
cord-256444-grw5s2pf	278	27	TGEV	TGEV	NNP
cord-256444-grw5s2pf	278	28	-	-	HYPH
cord-256444-grw5s2pf	278	29	infected	infect	VBN
cord-256444-grw5s2pf	278	30	cells	cell	NNS
cord-256444-grw5s2pf	279	1	(	(	-LRB-
cord-256444-grw5s2pf	279	2	Godet	Godet	NNP
cord-256444-grw5s2pf	279	3	et	et	NNP
cord-256444-grw5s2pf	279	4	al	al	NNP
cord-256444-grw5s2pf	279	5	.	.	NNP
cord-256444-grw5s2pf	279	6	,	,	,
cord-256444-grw5s2pf	279	7	1992	1992	CD
cord-256444-grw5s2pf	279	8	)	)	-RRB-
cord-256444-grw5s2pf	279	9	,	,	,
cord-256444-grw5s2pf	279	10	but	but	CC
cord-256444-grw5s2pf	279	11	the	the	DT
cord-256444-grw5s2pf	279	12	precise	precise	JJ
cord-256444-grw5s2pf	279	13	topology	topology	NN
cord-256444-grw5s2pf	279	14	of	of	IN
cord-256444-grw5s2pf	279	15	the	the	DT
cord-256444-grw5s2pf	279	16	protein	protein	NN
cord-256444-grw5s2pf	279	17	has	have	VBZ
cord-256444-grw5s2pf	279	18	not	not	RB
cord-256444-grw5s2pf	279	19	been	be	VBN
cord-256444-grw5s2pf	279	20	elucidated	elucidate	VBN
cord-256444-grw5s2pf	279	21	.	.	.
cord-256444-grw5s2pf	280	1	The	the	DT
cord-256444-grw5s2pf	280	2	role	role	NN
cord-256444-grw5s2pf	280	3	of	of	IN
cord-256444-grw5s2pf	280	4	the	the	DT
cord-256444-grw5s2pf	280	5	E	e	NN
cord-256444-grw5s2pf	280	6	protein	protein	NN
cord-256444-grw5s2pf	280	7	in	in	IN
cord-256444-grw5s2pf	280	8	virion	virion	NN
cord-256444-grw5s2pf	280	9	assembly	assembly	NN
cord-256444-grw5s2pf	280	10	will	will	MD
cord-256444-grw5s2pf	280	11	be	be	VB
cord-256444-grw5s2pf	280	12	discussed	discuss	VBN
cord-256444-grw5s2pf	280	13	in	in	IN
cord-256444-grw5s2pf	280	14	Section	section	NN
cord-256444-grw5s2pf	280	15	V	v	NN
cord-256444-grw5s2pf	280	16	,	,	,
cord-256444-grw5s2pf	280	17	H	H	NNP
cord-256444-grw5s2pf	280	18	on	on	IN
cord-256444-grw5s2pf	280	19	virus	virus	NN
cord-256444-grw5s2pf	280	20	assembly	assembly	NN
cord-256444-grw5s2pf	280	21	and	and	CC
cord-256444-grw5s2pf	280	22	release	release	NN
cord-256444-grw5s2pf	280	23	.	.	.
cord-256444-grw5s2pf	281	1	The	the	DT
cord-256444-grw5s2pf	281	2	E	e	NN
cord-256444-grw5s2pf	281	3	proteins	protein	NNS
cord-256444-grw5s2pf	281	4	of	of	IN
cord-256444-grw5s2pf	281	5	IBV	IBV	NNP
cord-256444-grw5s2pf	281	6	and	and	CC
cord-256444-grw5s2pf	281	7	MHV	MHV	NNP
cord-256444-grw5s2pf	281	8	are	be	VBP
cord-256444-grw5s2pf	281	9	translated	translate	VBN
cord-256444-grw5s2pf	281	10	from	from	IN
cord-256444-grw5s2pf	281	11	the	the	DT
cord-256444-grw5s2pf	281	12	third	third	JJ
cord-256444-grw5s2pf	281	13	and	and	CC
cord-256444-grw5s2pf	281	14	second	second	JJ
cord-256444-grw5s2pf	281	15	ORFs	orf	NNS
cord-256444-grw5s2pf	281	16	,	,	,
cord-256444-grw5s2pf	281	17	respectively	respectively	RB
cord-256444-grw5s2pf	281	18	,	,	,
cord-256444-grw5s2pf	281	19	of	of	IN
cord-256444-grw5s2pf	281	20	mRNAs	mrnas	CD
cord-256444-grw5s2pf	281	21	3	3	CD
cord-256444-grw5s2pf	281	22	and	and	CC
cord-256444-grw5s2pf	281	23	5	5	CD
cord-256444-grw5s2pf	281	24	of	of	IN
cord-256444-grw5s2pf	281	25	the	the	DT
cord-256444-grw5s2pf	281	26	respective	respective	JJ
cord-256444-grw5s2pf	281	27	viruses	virus	NNS
cord-256444-grw5s2pf	281	28	.	.	.
cord-256444-grw5s2pf	282	1	Both	both	DT
cord-256444-grw5s2pf	282	2	of	of	IN
cord-256444-grw5s2pf	282	3	these	these	DT
cord-256444-grw5s2pf	282	4	are	be	VBP
cord-256444-grw5s2pf	282	5	polycistronic	polycistronic	JJ
cord-256444-grw5s2pf	282	6	mRNAs	mRNAs	.
cord-256444-grw5s2pf	283	1	(	(	-LRB-
cord-256444-grw5s2pf	283	2	see	see	VB
cord-256444-grw5s2pf	283	3	Figs	Figs	NNPS
cord-256444-grw5s2pf	283	4	.	.	.
cord-256444-grw5s2pf	284	1	5	5	CD
cord-256444-grw5s2pf	284	2	and	and	CC
cord-256444-grw5s2pf	284	3	7	7	CD
cord-256444-grw5s2pf	284	4	and	and	CC
cord-256444-grw5s2pf	284	5	Section	Section	NNP
cord-256444-grw5s2pf	284	6	V	V	NNP
cord-256444-grw5s2pf	284	7	,	,	,
cord-256444-grw5s2pf	284	8	G,2	G,2	NNP
cord-256444-grw5s2pf	284	9	)	)	-RRB-
cord-256444-grw5s2pf	284	10	.	.	.
cord-256444-grw5s2pf	285	1	In	in	IN
cord-256444-grw5s2pf	285	2	contrast	contrast	NN
cord-256444-grw5s2pf	285	3	,	,	,
cord-256444-grw5s2pf	285	4	in	in	IN
cord-256444-grw5s2pf	285	5	all	all	DT
cord-256444-grw5s2pf	285	6	other	other	JJ
cord-256444-grw5s2pf	285	7	viruses	virus	NNS
cord-256444-grw5s2pf	285	8	,	,	,
cord-256444-grw5s2pf	285	9	the	the	DT
cord-256444-grw5s2pf	285	10	E	e	NN
cord-256444-grw5s2pf	285	11	protein	protein	NN
cord-256444-grw5s2pf	285	12	is	be	VBZ
cord-256444-grw5s2pf	285	13	derived	derive	VBN
cord-256444-grw5s2pf	285	14	from	from	IN
cord-256444-grw5s2pf	285	15	a	a	DT
cord-256444-grw5s2pf	285	16	monocistronic	monocistronic	NN
cord-256444-grw5s2pf	285	17	mRNA	mrna	NN
cord-256444-grw5s2pf	285	18	.	.	.
cord-256444-grw5s2pf	286	1	The	the	DT
cord-256444-grw5s2pf	286	2	mechanism	mechanism	NN
cord-256444-grw5s2pf	286	3	of	of	IN
cord-256444-grw5s2pf	286	4	translation	translation	NN
cord-256444-grw5s2pf	286	5	of	of	IN
cord-256444-grw5s2pf	286	6	the	the	DT
cord-256444-grw5s2pf	286	7	IBV	IBV	NNP
cord-256444-grw5s2pf	286	8	and	and	CC
cord-256444-grw5s2pf	286	9	MHV	MHV	NNP
cord-256444-grw5s2pf	286	10	E	e	NN
cord-256444-grw5s2pf	286	11	proteins	protein	NNS
cord-256444-grw5s2pf	286	12	is	be	VBZ
cord-256444-grw5s2pf	286	13	discussed	discuss	VBN
cord-256444-grw5s2pf	286	14	in	in	IN
cord-256444-grw5s2pf	286	15	Section	section	NN
cord-256444-grw5s2pf	286	16	V	v	NN
cord-256444-grw5s2pf	286	17	,	,	,
cord-256444-grw5s2pf	286	18	G.	G.	NNP
cord-256444-grw5s2pf	287	1	The	the	DT
cord-256444-grw5s2pf	287	2	N	N	NNP
cord-256444-grw5s2pf	287	3	protein	protein	NN
cord-256444-grw5s2pf	287	4	is	be	VBZ
cord-256444-grw5s2pf	287	5	a	a	DT
cord-256444-grw5s2pf	287	6	50-to	50-to	CD
cord-256444-grw5s2pf	287	7	60-kDa	60-kda	CD
cord-256444-grw5s2pf	287	8	phosphoprotein	phosphoprotein	NN
cord-256444-grw5s2pf	287	9	which	which	WDT
cord-256444-grw5s2pf	287	10	,	,	,
cord-256444-grw5s2pf	287	11	together	together	RB
cord-256444-grw5s2pf	287	12	with	with	IN
cord-256444-grw5s2pf	287	13	the	the	DT
cord-256444-grw5s2pf	287	14	genomic	genomic	JJ
cord-256444-grw5s2pf	287	15	RNA	RNA	NNP
cord-256444-grw5s2pf	287	16	,	,	,
cord-256444-grw5s2pf	287	17	forms	form	VBZ
cord-256444-grw5s2pf	287	18	a	a	DT
cord-256444-grw5s2pf	287	19	helical	helical	JJ
cord-256444-grw5s2pf	287	20	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	287	21	(	(	-LRB-
cord-256444-grw5s2pf	287	22	RNP	RNP	NNP
cord-256444-grw5s2pf	287	23	)	)	-RRB-
cord-256444-grw5s2pf	287	24	.	.	.
cord-256444-grw5s2pf	288	1	The	the	DT
cord-256444-grw5s2pf	288	2	RNP	RNP	NNP
cord-256444-grw5s2pf	288	3	of	of	IN
cord-256444-grw5s2pf	288	4	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	288	5	have	have	VBP
cord-256444-grw5s2pf	288	6	been	be	VBN
cord-256444-grw5s2pf	288	7	reported	report	VBN
cord-256444-grw5s2pf	288	8	variously	variously	RB
cord-256444-grw5s2pf	288	9	as	as	IN
cord-256444-grw5s2pf	288	10	being	be	VBG
cord-256444-grw5s2pf	288	11	from	from	IN
cord-256444-grw5s2pf	288	12	9	9	CD
cord-256444-grw5s2pf	288	13	-	-	SYM
cord-256444-grw5s2pf	288	14	11	11	CD
cord-256444-grw5s2pf	288	15	to	to	TO
cord-256444-grw5s2pf	288	16	14	14	CD
cord-256444-grw5s2pf	288	17	-	-	SYM
cord-256444-grw5s2pf	288	18	16	16	CD
cord-256444-grw5s2pf	288	19	nm	nm	NN
cord-256444-grw5s2pf	288	20	in	in	IN
cord-256444-grw5s2pf	288	21	diameter	diameter	NN
cord-256444-grw5s2pf	288	22	(	(	-LRB-
cord-256444-grw5s2pf	288	23	see	see	VB
cord-256444-grw5s2pf	288	24	Laude	Laude	NNP
cord-256444-grw5s2pf	288	25	and	and	CC
cord-256444-grw5s2pf	288	26	Masters	Masters	NNPS
cord-256444-grw5s2pf	288	27	,	,	,
cord-256444-grw5s2pf	288	28	1995	1995	CD
cord-256444-grw5s2pf	288	29	,	,	,
cord-256444-grw5s2pf	288	30	for	for	IN
cord-256444-grw5s2pf	288	31	references	reference	NNS
cord-256444-grw5s2pf	288	32	)	)	-RRB-
cord-256444-grw5s2pf	288	33	.	.	.
cord-256444-grw5s2pf	289	1	The	the	DT
cord-256444-grw5s2pf	289	2	N	n	CD
cord-256444-grw5s2pf	289	3	protein	protein	NN
cord-256444-grw5s2pf	289	4	in	in	IN
cord-256444-grw5s2pf	289	5	RNP	RNP	NNP
cord-256444-grw5s2pf	289	6	provides	provide	VBZ
cord-256444-grw5s2pf	289	7	only	only	RB
cord-256444-grw5s2pf	289	8	limited	limited	JJ
cord-256444-grw5s2pf	289	9	protection	protection	NN
cord-256444-grw5s2pf	289	10	to	to	IN
cord-256444-grw5s2pf	289	11	the	the	DT
cord-256444-grw5s2pf	289	12	RNA	RNA	NNP
cord-256444-grw5s2pf	289	13	genome	genome	NN
cord-256444-grw5s2pf	289	14	against	against	IN
cord-256444-grw5s2pf	289	15	ribonucleases	ribonuclease	NNS
cord-256444-grw5s2pf	289	16	.	.	.
cord-256444-grw5s2pf	290	1	The	the	DT
cord-256444-grw5s2pf	290	2	N	n	CD
cord-256444-grw5s2pf	290	3	proteins	protein	NNS
cord-256444-grw5s2pf	290	4	vary	vary	VBP
cord-256444-grw5s2pf	290	5	from	from	IN
cord-256444-grw5s2pf	290	6	377	377	CD
cord-256444-grw5s2pf	290	7	to	to	TO
cord-256444-grw5s2pf	290	8	455	455	CD
cord-256444-grw5s2pf	290	9	amino	amino	JJ
cord-256444-grw5s2pf	290	10	acids	acid	NNS
cord-256444-grw5s2pf	290	11	in	in	IN
cord-256444-grw5s2pf	290	12	length	length	NN
cord-256444-grw5s2pf	290	13	,	,	,
cord-256444-grw5s2pf	290	14	are	be	VBP
cord-256444-grw5s2pf	290	15	highly	highly	RB
cord-256444-grw5s2pf	290	16	basic	basic	JJ
cord-256444-grw5s2pf	290	17	,	,	,
cord-256444-grw5s2pf	290	18	and	and	CC
cord-256444-grw5s2pf	290	19	have	have	VBP
cord-256444-grw5s2pf	290	20	a	a	DT
cord-256444-grw5s2pf	290	21	high	high	JJ
cord-256444-grw5s2pf	290	22	(	(	-LRB-
cord-256444-grw5s2pf	290	23	7	7	CD
cord-256444-grw5s2pf	290	24	-	-	SYM
cord-256444-grw5s2pf	290	25	11	11	CD
cord-256444-grw5s2pf	290	26	%	%	NN
cord-256444-grw5s2pf	290	27	)	)	-RRB-
cord-256444-grw5s2pf	290	28	serine	serine	NN
cord-256444-grw5s2pf	290	29	content	content	NN
cord-256444-grw5s2pf	290	30	,	,	,
cord-256444-grw5s2pf	290	31	potential	potential	JJ
cord-256444-grw5s2pf	290	32	targets	target	NNS
cord-256444-grw5s2pf	290	33	for	for	IN
cord-256444-grw5s2pf	290	34	phosphorylation	phosphorylation	NN
cord-256444-grw5s2pf	290	35	.	.	.
cord-256444-grw5s2pf	291	1	Sequence	sequence	NN
cord-256444-grw5s2pf	291	2	conservation	conservation	NN
cord-256444-grw5s2pf	291	3	within	within	IN
cord-256444-grw5s2pf	291	4	the	the	DT
cord-256444-grw5s2pf	291	5	genus	genus	NN
cord-256444-grw5s2pf	291	6	is	be	VBZ
cord-256444-grw5s2pf	291	7	low	low	JJ
cord-256444-grw5s2pf	291	8	.	.	.
cord-256444-grw5s2pf	292	1	Thus	thus	RB
cord-256444-grw5s2pf	292	2	,	,	,
cord-256444-grw5s2pf	292	3	the	the	DT
cord-256444-grw5s2pf	292	4	N	n	CD
cord-256444-grw5s2pf	292	5	proteins	protein	NNS
cord-256444-grw5s2pf	292	6	of	of	IN
cord-256444-grw5s2pf	292	7	IBV	IBV	NNP
cord-256444-grw5s2pf	292	8	and	and	CC
cord-256444-grw5s2pf	292	9	TGEV	TGEV	NNP
cord-256444-grw5s2pf	292	10	have	have	VBP
cord-256444-grw5s2pf	292	11	only	only	RB
cord-256444-grw5s2pf	292	12	29	29	CD
cord-256444-grw5s2pf	292	13	%	%	NN
cord-256444-grw5s2pf	292	14	identity	identity	NN
cord-256444-grw5s2pf	292	15	with	with	IN
cord-256444-grw5s2pf	292	16	that	that	DT
cord-256444-grw5s2pf	292	17	of	of	IN
cord-256444-grw5s2pf	292	18	BCV	BCV	NNP
cord-256444-grw5s2pf	292	19	.	.	.
cord-256444-grw5s2pf	293	1	Even	even	RB
cord-256444-grw5s2pf	293	2	within	within	IN
cord-256444-grw5s2pf	293	3	the	the	DT
cord-256444-grw5s2pf	293	4	MHV	MHV	NNP
cord-256444-grw5s2pf	293	5	group	group	NN
cord-256444-grw5s2pf	293	6	,	,	,
cord-256444-grw5s2pf	293	7	the	the	DT
cord-256444-grw5s2pf	293	8	N	n	CD
cord-256444-grw5s2pf	293	9	proteins	protein	NNS
cord-256444-grw5s2pf	293	10	of	of	IN
cord-256444-grw5s2pf	293	11	MHV	MHV	NNP
cord-256444-grw5s2pf	293	12	and	and	CC
cord-256444-grw5s2pf	293	13	BCV	BCV	NNP
cord-256444-grw5s2pf	293	14	share	share	VBP
cord-256444-grw5s2pf	293	15	only	only	RB
cord-256444-grw5s2pf	293	16	70	70	CD
cord-256444-grw5s2pf	293	17	%	%	NN
cord-256444-grw5s2pf	293	18	identity	identity	NN
cord-256444-grw5s2pf	293	19	,	,	,
cord-256444-grw5s2pf	293	20	whereas	whereas	IN
cord-256444-grw5s2pf	293	21	the	the	DT
cord-256444-grw5s2pf	293	22	M	M	NNP
cord-256444-grw5s2pf	293	23	proteins	protein	NNS
cord-256444-grw5s2pf	293	24	of	of	IN
cord-256444-grw5s2pf	293	25	these	these	DT
cord-256444-grw5s2pf	293	26	two	two	CD
cord-256444-grw5s2pf	293	27	viruses	virus	NNS
cord-256444-grw5s2pf	293	28	have	have	VBP
cord-256444-grw5s2pf	293	29	86	86	CD
cord-256444-grw5s2pf	293	30	%	%	NN
cord-256444-grw5s2pf	293	31	identity	identity	NN
cord-256444-grw5s2pf	294	1	(	(	-LRB-
cord-256444-grw5s2pf	294	2	Lapps	Lapps	NNP
cord-256444-grw5s2pf	294	3	et	et	NNP
cord-256444-grw5s2pf	294	4	al	al	NNP
cord-256444-grw5s2pf	294	5	.	.	NNP
cord-256444-grw5s2pf	294	6	,	,	,
cord-256444-grw5s2pf	294	7	1987	1987	CD
cord-256444-grw5s2pf	294	8	)	)	-RRB-
cord-256444-grw5s2pf	294	9	.	.	.
cord-256444-grw5s2pf	295	1	Based	base	VBN
cord-256444-grw5s2pf	295	2	on	on	IN
cord-256444-grw5s2pf	295	3	sequence	sequence	NN
cord-256444-grw5s2pf	295	4	comparison	comparison	NN
cord-256444-grw5s2pf	295	5	,	,	,
cord-256444-grw5s2pf	295	6	three	three	CD
cord-256444-grw5s2pf	295	7	structural	structural	JJ
cord-256444-grw5s2pf	295	8	domains	domain	NNS
cord-256444-grw5s2pf	295	9	in	in	IN
cord-256444-grw5s2pf	295	10	the	the	DT
cord-256444-grw5s2pf	295	11	N	N	NNP
cord-256444-grw5s2pf	295	12	protein	protein	NN
cord-256444-grw5s2pf	295	13	have	have	VBP
cord-256444-grw5s2pf	295	14	been	be	VBN
cord-256444-grw5s2pf	295	15	identified	identify	VBN
cord-256444-grw5s2pf	295	16	(	(	-LRB-
cord-256444-grw5s2pf	295	17	Parker	Parker	NNP
cord-256444-grw5s2pf	295	18	and	and	CC
cord-256444-grw5s2pf	295	19	Masters	Masters	NNP
cord-256444-grw5s2pf	295	20	,	,	,
cord-256444-grw5s2pf	295	21	1990	1990	CD
cord-256444-grw5s2pf	295	22	)	)	-RRB-
cord-256444-grw5s2pf	295	23	.	.	.
cord-256444-grw5s2pf	296	1	The	the	DT
cord-256444-grw5s2pf	296	2	middle	middle	JJ
cord-256444-grw5s2pf	296	3	domain	domain	NN
cord-256444-grw5s2pf	296	4	is	be	VBZ
cord-256444-grw5s2pf	296	5	an	an	DT
cord-256444-grw5s2pf	296	6	RNA	rna	NN
cord-256444-grw5s2pf	296	7	-	-	HYPH
cord-256444-grw5s2pf	296	8	binding	bind	VBG
cord-256444-grw5s2pf	296	9	domain	domain	NN
cord-256444-grw5s2pf	296	10	(	(	-LRB-
cord-256444-grw5s2pf	296	11	Masters	master	NNS
cord-256444-grw5s2pf	296	12	,	,	,
cord-256444-grw5s2pf	296	13	1992	1992	CD
cord-256444-grw5s2pf	296	14	;	;	:
cord-256444-grw5s2pf	296	15	Nelson	Nelson	NNP
cord-256444-grw5s2pf	296	16	and	and	CC
cord-256444-grw5s2pf	296	17	Stohlman	Stohlman	NNP
cord-256444-grw5s2pf	296	18	,	,	,
cord-256444-grw5s2pf	296	19	1993	1993	CD
cord-256444-grw5s2pf	296	20	)	)	-RRB-
cord-256444-grw5s2pf	296	21	which	which	WDT
cord-256444-grw5s2pf	296	22	binds	bind	VBZ
cord-256444-grw5s2pf	296	23	to	to	IN
cord-256444-grw5s2pf	296	24	both	both	CC
cord-256444-grw5s2pf	296	25	coronaviral	coronaviral	JJ
cord-256444-grw5s2pf	296	26	and	and	CC
cord-256444-grw5s2pf	296	27	nonviral	nonviral	NNP
cord-256444-grw5s2pf	296	28	RNA	RNA	NNP
cord-256444-grw5s2pf	296	29	sequences	sequence	NNS
cord-256444-grw5s2pf	296	30	in	in	IN
cord-256444-grw5s2pf	296	31	uitro	uitro	NNP
cord-256444-grw5s2pf	296	32	(	(	-LRB-
cord-256444-grw5s2pf	296	33	Robbins	Robbins	NNP
cord-256444-grw5s2pf	296	34	et	et	NNP
cord-256444-grw5s2pf	296	35	al	al	NNP
cord-256444-grw5s2pf	296	36	.	.	.
cord-256444-grw5s2pf	297	1	,	,	,
cord-256444-grw5s2pf	297	2	1986	1986	CD
cord-256444-grw5s2pf	297	3	;	;	:
cord-256444-grw5s2pf	297	4	Stohlman	Stohlman	NNP
cord-256444-grw5s2pf	297	5	et	et	NNP
cord-256444-grw5s2pf	297	6	al	al	NNP
cord-256444-grw5s2pf	297	7	.	.	NNP
cord-256444-grw5s2pf	297	8	,	,	,
cord-256444-grw5s2pf	297	9	1988	1988	CD
cord-256444-grw5s2pf	297	10	;	;	:
cord-256444-grw5s2pf	297	11	Masters	Masters	NNPS
cord-256444-grw5s2pf	297	12	,	,	,
cord-256444-grw5s2pf	297	13	1992	1992	CD
cord-256444-grw5s2pf	297	14	)	)	-RRB-
cord-256444-grw5s2pf	297	15	;	;	:
cord-256444-grw5s2pf	297	16	however	however	RB
cord-256444-grw5s2pf	297	17	,	,	,
cord-256444-grw5s2pf	297	18	it	-PRON-	PRP
cord-256444-grw5s2pf	297	19	does	do	VBZ
cord-256444-grw5s2pf	297	20	not	not	RB
cord-256444-grw5s2pf	297	21	contain	contain	VB
cord-256444-grw5s2pf	297	22	any	any	DT
cord-256444-grw5s2pf	297	23	motifs	motif	NNS
cord-256444-grw5s2pf	297	24	characteristic	characteristic	JJ
cord-256444-grw5s2pf	297	25	of	of	IN
cord-256444-grw5s2pf	297	26	other	other	JJ
cord-256444-grw5s2pf	297	27	RNA	RNA	NNP
cord-256444-grw5s2pf	297	28	-	-	HYPH
cord-256444-grw5s2pf	297	29	binding	bind	VBG
cord-256444-grw5s2pf	297	30	proteins	protein	NNS
cord-256444-grw5s2pf	297	31	.	.	.
cord-256444-grw5s2pf	298	1	Under	under	IN
cord-256444-grw5s2pf	298	2	specific	specific	JJ
cord-256444-grw5s2pf	298	3	binding	bind	VBG
cord-256444-grw5s2pf	298	4	conditions	condition	NNS
cord-256444-grw5s2pf	298	5	,	,	,
cord-256444-grw5s2pf	298	6	the	the	DT
cord-256444-grw5s2pf	298	7	MHV	MHV	NNP
cord-256444-grw5s2pf	298	8	N	N	NNP
cord-256444-grw5s2pf	298	9	protein	protein	NN
cord-256444-grw5s2pf	298	10	binds	bind	VBZ
cord-256444-grw5s2pf	298	11	to	to	IN
cord-256444-grw5s2pf	298	12	the	the	DT
cord-256444-grw5s2pf	298	13	leader	leader	NN
cord-256444-grw5s2pf	298	14	RNA	RNA	NNP
cord-256444-grw5s2pf	298	15	sequence	sequence	NN
cord-256444-grw5s2pf	298	16	,	,	,
cord-256444-grw5s2pf	298	17	particularly	particularly	RB
cord-256444-grw5s2pf	298	18	nucleotides	nucleotide	NNS
cord-256444-grw5s2pf	298	19	56	56	CD
cord-256444-grw5s2pf	298	20	-	-	SYM
cord-256444-grw5s2pf	298	21	67	67	CD
cord-256444-grw5s2pf	298	22	.	.	.
cord-256444-grw5s2pf	299	1	Furthermore	furthermore	RB
cord-256444-grw5s2pf	299	2	,	,	,
cord-256444-grw5s2pf	299	3	an	an	DT
cord-256444-grw5s2pf	299	4	anti	anti	JJ
cord-256444-grw5s2pf	299	5	-	-	JJ
cord-256444-grw5s2pf	299	6	N	n	JJ
cord-256444-grw5s2pf	299	7	MAb	MAb	NNPS
cord-256444-grw5s2pf	299	8	immunoprecipitated	immunoprecipitate	VBD
cord-256444-grw5s2pf	299	9	all	all	DT
cord-256444-grw5s2pf	299	10	of	of	IN
cord-256444-grw5s2pf	299	11	the	the	DT
cord-256444-grw5s2pf	299	12	MHV	MHV	NNP
cord-256444-grw5s2pf	299	13	RNA	RNA	NNP
cord-256444-grw5s2pf	299	14	molecules	molecule	NNS
cord-256444-grw5s2pf	299	15	which	which	WDT
cord-256444-grw5s2pf	299	16	had	have	VBD
cord-256444-grw5s2pf	299	17	the	the	DT
cord-256444-grw5s2pf	299	18	leader	leader	NN
cord-256444-grw5s2pf	299	19	sequence	sequence	NN
cord-256444-grw5s2pf	299	20	.	.	.
cord-256444-grw5s2pf	300	1	The	the	DT
cord-256444-grw5s2pf	300	2	N	n	CD
cord-256444-grw5s2pf	300	3	protein	protein	NN
cord-256444-grw5s2pf	300	4	of	of	IN
cord-256444-grw5s2pf	300	5	IBV	IBV	NNP
cord-256444-grw5s2pf	300	6	also	also	RB
cord-256444-grw5s2pf	300	7	bound	bind	VBN
cord-256444-grw5s2pf	300	8	to	to	IN
cord-256444-grw5s2pf	300	9	the	the	DT
cord-256444-grw5s2pf	300	10	3	3	CD
cord-256444-grw5s2pf	300	11	'	'	POS
cord-256444-grw5s2pf	300	12	untranslated	untranslated	JJ
cord-256444-grw5s2pf	300	13	region	region	NN
cord-256444-grw5s2pf	300	14	of	of	IN
cord-256444-grw5s2pf	300	15	the	the	DT
cord-256444-grw5s2pf	300	16	IBV	IBV	NNP
cord-256444-grw5s2pf	300	17	RNA	RNA	NNP
cord-256444-grw5s2pf	300	18	in	in	IN
cord-256444-grw5s2pf	300	19	uitro	uitro	NNP
cord-256444-grw5s2pf	301	1	(	(	-LRB-
cord-256444-grw5s2pf	301	2	Zhou	Zhou	NNP
cord-256444-grw5s2pf	301	3	et	et	NNP
cord-256444-grw5s2pf	301	4	al	al	NNP
cord-256444-grw5s2pf	301	5	.	.	NNP
cord-256444-grw5s2pf	301	6	,	,	,
cord-256444-grw5s2pf	301	7	1996	1996	CD
cord-256444-grw5s2pf	301	8	)	)	-RRB-
cord-256444-grw5s2pf	301	9	.	.	.
cord-256444-grw5s2pf	302	1	These	these	DT
cord-256444-grw5s2pf	302	2	RNA	RNA	NNP
cord-256444-grw5s2pf	302	3	-	-	HYPH
cord-256444-grw5s2pf	302	4	binding	bind	VBG
cord-256444-grw5s2pf	302	5	properties	property	NNS
cord-256444-grw5s2pf	302	6	are	be	VBP
cord-256444-grw5s2pf	302	7	consistent	consistent	JJ
cord-256444-grw5s2pf	302	8	with	with	IN
cord-256444-grw5s2pf	302	9	the	the	DT
cord-256444-grw5s2pf	302	10	fact	fact	NN
cord-256444-grw5s2pf	302	11	that	that	IN
cord-256444-grw5s2pf	302	12	the	the	DT
cord-256444-grw5s2pf	302	13	N	N	NNP
cord-256444-grw5s2pf	302	14	protein	protein	NN
cord-256444-grw5s2pf	302	15	interacts	interact	VBZ
cord-256444-grw5s2pf	302	16	with	with	IN
cord-256444-grw5s2pf	302	17	the	the	DT
cord-256444-grw5s2pf	302	18	viral	viral	JJ
cord-256444-grw5s2pf	302	19	genomic	genomic	JJ
cord-256444-grw5s2pf	302	20	RNA	RNA	NNP
cord-256444-grw5s2pf	302	21	to	to	TO
cord-256444-grw5s2pf	302	22	form	form	VB
cord-256444-grw5s2pf	302	23	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	302	24	.	.	.
cord-256444-grw5s2pf	303	1	This	this	DT
cord-256444-grw5s2pf	303	2	interaction	interaction	NN
cord-256444-grw5s2pf	303	3	is	be	VBZ
cord-256444-grw5s2pf	303	4	necessary	necessary	JJ
cord-256444-grw5s2pf	303	5	for	for	IN
cord-256444-grw5s2pf	303	6	the	the	DT
cord-256444-grw5s2pf	303	7	formation	formation	NN
cord-256444-grw5s2pf	303	8	of	of	IN
cord-256444-grw5s2pf	303	9	virus	virus	NN
cord-256444-grw5s2pf	303	10	particles	particle	NNS
cord-256444-grw5s2pf	303	11	,	,	,
cord-256444-grw5s2pf	303	12	as	as	IN
cord-256444-grw5s2pf	303	13	N	n	CD
cord-256444-grw5s2pf	303	14	alone	alone	RB
cord-256444-grw5s2pf	303	15	can	can	MD
cord-256444-grw5s2pf	303	16	not	not	RB
cord-256444-grw5s2pf	303	17	be	be	VB
cord-256444-grw5s2pf	303	18	incorporated	incorporate	VBN
cord-256444-grw5s2pf	303	19	into	into	IN
cord-256444-grw5s2pf	303	20	virus	virus	NN
cord-256444-grw5s2pf	303	21	particles	particle	NNS
cord-256444-grw5s2pf	303	22	,	,	,
cord-256444-grw5s2pf	303	23	whereas	whereas	IN
cord-256444-grw5s2pf	303	24	the	the	DT
cord-256444-grw5s2pf	303	25	N	N	NNP
cord-256444-grw5s2pf	303	26	-	-	HYPH
cord-256444-grw5s2pf	303	27	RNA	RNA	NNP
cord-256444-grw5s2pf	303	28	complex	complex	NN
cord-256444-grw5s2pf	303	29	can	can	MD
cord-256444-grw5s2pf	303	30	(	(	-LRB-
cord-256444-grw5s2pf	303	31	Bos	Bos	NNP
cord-256444-grw5s2pf	303	32	et	et	NNP
cord-256444-grw5s2pf	303	33	al	al	NNP
cord-256444-grw5s2pf	303	34	.	.	NNP
cord-256444-grw5s2pf	303	35	,	,	,
cord-256444-grw5s2pf	303	36	1996	1996	CD
cord-256444-grw5s2pf	303	37	;	;	:
cord-256444-grw5s2pf	303	38	Vennema	Vennema	NNP
cord-256444-grw5s2pf	303	39	et	et	NNP
cord-256444-grw5s2pf	303	40	aZ.	az.	NN
cord-256444-grw5s2pf	303	41	,	,	,
cord-256444-grw5s2pf	303	42	1996	1996	CD
cord-256444-grw5s2pf	303	43	)	)	-RRB-
cord-256444-grw5s2pf	303	44	.	.	.
cord-256444-grw5s2pf	304	1	However	however	RB
cord-256444-grw5s2pf	304	2	,	,	,
cord-256444-grw5s2pf	304	3	the	the	DT
cord-256444-grw5s2pf	304	4	specificity	specificity	NN
cord-256444-grw5s2pf	304	5	of	of	IN
cord-256444-grw5s2pf	304	6	the	the	DT
cord-256444-grw5s2pf	304	7	RNA	RNA	NNP
cord-256444-grw5s2pf	304	8	-	-	HYPH
cord-256444-grw5s2pf	304	9	N	N	NNP
cord-256444-grw5s2pf	304	10	protein	protein	NN
cord-256444-grw5s2pf	304	11	interaction	interaction	NN
cord-256444-grw5s2pf	304	12	required	require	VBN
cord-256444-grw5s2pf	304	13	for	for	IN
cord-256444-grw5s2pf	304	14	nucleocapsid	nucleocapsid	NNP
cord-256444-grw5s2pf	304	15	formation	formation	NN
cord-256444-grw5s2pf	304	16	has	have	VBZ
cord-256444-grw5s2pf	304	17	not	not	RB
cord-256444-grw5s2pf	304	18	been	be	VBN
cord-256444-grw5s2pf	304	19	elucidated	elucidate	VBN
cord-256444-grw5s2pf	304	20	.	.	.
cord-256444-grw5s2pf	305	1	The	the	DT
cord-256444-grw5s2pf	305	2	N	N	NNP
cord-256444-grw5s2pf	305	3	protein	protein	NN
cord-256444-grw5s2pf	305	4	also	also	RB
cord-256444-grw5s2pf	305	5	binds	bind	VBZ
cord-256444-grw5s2pf	305	6	to	to	IN
cord-256444-grw5s2pf	305	7	membranes	membrane	NNS
cord-256444-grw5s2pf	305	8	and	and	CC
cord-256444-grw5s2pf	305	9	phospholipid	phospholipid	NN
cord-256444-grw5s2pf	305	10	(	(	-LRB-
cord-256444-grw5s2pf	305	11	Anderson	Anderson	NNP
cord-256444-grw5s2pf	305	12	and	and	CC
cord-256444-grw5s2pf	305	13	Wong	Wong	NNP
cord-256444-grw5s2pf	305	14	,	,	,
cord-256444-grw5s2pf	305	15	1993	1993	CD
cord-256444-grw5s2pf	305	16	)	)	-RRB-
cord-256444-grw5s2pf	305	17	.	.	.
cord-256444-grw5s2pf	306	1	This	this	DT
cord-256444-grw5s2pf	306	2	may	may	MD
cord-256444-grw5s2pf	306	3	be	be	VB
cord-256444-grw5s2pf	306	4	another	another	DT
cord-256444-grw5s2pf	306	5	property	property	NN
cord-256444-grw5s2pf	306	6	which	which	WDT
cord-256444-grw5s2pf	306	7	facilitates	facilitate	VBZ
cord-256444-grw5s2pf	306	8	the	the	DT
cord-256444-grw5s2pf	306	9	formation	formation	NN
cord-256444-grw5s2pf	306	10	of	of	IN
cord-256444-grw5s2pf	306	11	virus	virus	NN
cord-256444-grw5s2pf	306	12	particles	particle	NNS
cord-256444-grw5s2pf	306	13	.	.	.
cord-256444-grw5s2pf	307	1	The	the	DT
cord-256444-grw5s2pf	307	2	finding	finding	NN
cord-256444-grw5s2pf	307	3	that	that	IN
cord-256444-grw5s2pf	307	4	the	the	DT
cord-256444-grw5s2pf	307	5	N	N	NNP
cord-256444-grw5s2pf	307	6	protein	protein	NN
cord-256444-grw5s2pf	307	7	binds	bind	VBZ
cord-256444-grw5s2pf	307	8	to	to	IN
cord-256444-grw5s2pf	307	9	the	the	DT
cord-256444-grw5s2pf	307	10	5	5	CD
cord-256444-grw5s2pf	307	11	'	'	''
cord-256444-grw5s2pf	307	12	and	and	CC
cord-256444-grw5s2pf	307	13	3	3	CD
cord-256444-grw5s2pf	307	14	'	'	POS
cord-256444-grw5s2pf	307	15	ends	end	NNS
cord-256444-grw5s2pf	307	16	of	of	IN
cord-256444-grw5s2pf	307	17	viral	viral	JJ
cord-256444-grw5s2pf	307	18	RNA	RNA	NNP
cord-256444-grw5s2pf	307	19	suggests	suggest	VBZ
cord-256444-grw5s2pf	307	20	that	that	IN
cord-256444-grw5s2pf	307	21	the	the	DT
cord-256444-grw5s2pf	307	22	N	n	CD
cord-256444-grw5s2pf	307	23	protein	protein	NN
cord-256444-grw5s2pf	307	24	may	may	MD
cord-256444-grw5s2pf	307	25	also	also	RB
cord-256444-grw5s2pf	307	26	modulate	modulate	VB
cord-256444-grw5s2pf	307	27	viral	viral	JJ
cord-256444-grw5s2pf	307	28	RNA	RNA	NNP
cord-256444-grw5s2pf	307	29	synthesis	synthesis	NN
cord-256444-grw5s2pf	307	30	because	because	IN
cord-256444-grw5s2pf	307	31	the	the	DT
cord-256444-grw5s2pf	307	32	ends	end	NNS
cord-256444-grw5s2pf	307	33	of	of	IN
cord-256444-grw5s2pf	307	34	the	the	DT
cord-256444-grw5s2pf	307	35	RNA	RNA	NNP
cord-256444-grw5s2pf	307	36	are	be	VBP
cord-256444-grw5s2pf	307	37	likely	likely	RB
cord-256444-grw5s2pf	307	38	involved	involve	VBN
cord-256444-grw5s2pf	307	39	in	in	IN
cord-256444-grw5s2pf	307	40	the	the	DT
cord-256444-grw5s2pf	307	41	regulation	regulation	NN
cord-256444-grw5s2pf	307	42	of	of	IN
cord-256444-grw5s2pf	307	43	RNA	RNA	NNP
cord-256444-grw5s2pf	307	44	synthesis	synthesis	NN
cord-256444-grw5s2pf	307	45	.	.	.
cord-256444-grw5s2pf	308	1	In	in	IN
cord-256444-grw5s2pf	308	2	an	an	DT
cord-256444-grw5s2pf	308	3	in	in	IN
cord-256444-grw5s2pf	308	4	uitro	uitro	NNP
cord-256444-grw5s2pf	308	5	RNA	RNA	NNP
cord-256444-grw5s2pf	308	6	replication	replication	NN
cord-256444-grw5s2pf	308	7	system	system	NN
cord-256444-grw5s2pf	308	8	,	,	,
cord-256444-grw5s2pf	308	9	the	the	DT
cord-256444-grw5s2pf	308	10	addition	addition	NN
cord-256444-grw5s2pf	308	11	of	of	IN
cord-256444-grw5s2pf	308	12	MHV	MHV	NNP
cord-256444-grw5s2pf	308	13	N	N	NNP
cord-256444-grw5s2pf	308	14	-	-	HYPH
cord-256444-grw5s2pf	308	15	specific	specific	JJ
cord-256444-grw5s2pf	308	16	antibodies	antibody	NNS
cord-256444-grw5s2pf	308	17	inhibited	inhibit	VBD
cord-256444-grw5s2pf	308	18	viral	viral	JJ
cord-256444-grw5s2pf	308	19	RNA	RNA	NNP
cord-256444-grw5s2pf	308	20	synthesis	synthesis	NN
cord-256444-grw5s2pf	308	21	(	(	-LRB-
cord-256444-grw5s2pf	308	22	Compton	Compton	NNP
cord-256444-grw5s2pf	308	23	et	et	NNP
cord-256444-grw5s2pf	308	24	al	al	NNP
cord-256444-grw5s2pf	308	25	.	.	NNP
cord-256444-grw5s2pf	308	26	,	,	,
cord-256444-grw5s2pf	308	27	1987	1987	CD
cord-256444-grw5s2pf	308	28	)	)	-RRB-
cord-256444-grw5s2pf	308	29	,	,	,
cord-256444-grw5s2pf	308	30	suggesting	suggest	VBG
cord-256444-grw5s2pf	308	31	that	that	IN
cord-256444-grw5s2pf	308	32	the	the	DT
cord-256444-grw5s2pf	308	33	N	N	NNP
cord-256444-grw5s2pf	308	34	protein	protein	NN
cord-256444-grw5s2pf	308	35	is	be	VBZ
cord-256444-grw5s2pf	308	36	a	a	DT
cord-256444-grw5s2pf	308	37	component	component	NN
cord-256444-grw5s2pf	308	38	of	of	IN
cord-256444-grw5s2pf	308	39	the	the	DT
cord-256444-grw5s2pf	308	40	RNAsynthesizing	rnasynthesizing	NN
cord-256444-grw5s2pf	308	41	machinery	machinery	NN
cord-256444-grw5s2pf	308	42	.	.	.
cord-256444-grw5s2pf	309	1	The	the	DT
cord-256444-grw5s2pf	309	2	ability	ability	NN
cord-256444-grw5s2pf	309	3	of	of	IN
cord-256444-grw5s2pf	309	4	N	n	NN
cord-256444-grw5s2pf	309	5	to	to	TO
cord-256444-grw5s2pf	309	6	bind	bind	VB
cord-256444-grw5s2pf	309	7	to	to	IN
cord-256444-grw5s2pf	309	8	the	the	DT
cord-256444-grw5s2pf	309	9	membrane	membrane	NN
cord-256444-grw5s2pf	309	10	(	(	-LRB-
cord-256444-grw5s2pf	309	11	Anderson	Anderson	NNP
cord-256444-grw5s2pf	309	12	and	and	CC
cord-256444-grw5s2pf	309	13	Wong	Wong	NNP
cord-256444-grw5s2pf	309	14	,	,	,
cord-256444-grw5s2pf	309	15	1993	1993	CD
cord-256444-grw5s2pf	309	16	)	)	-RRB-
cord-256444-grw5s2pf	309	17	may	may	MD
cord-256444-grw5s2pf	309	18	enable	enable	VB
cord-256444-grw5s2pf	309	19	the	the	DT
cord-256444-grw5s2pf	309	20	formation	formation	NN
cord-256444-grw5s2pf	309	21	of	of	IN
cord-256444-grw5s2pf	309	22	the	the	DT
cord-256444-grw5s2pf	309	23	RNA	RNA	NNP
cord-256444-grw5s2pf	309	24	replication	replication	NN
cord-256444-grw5s2pf	309	25	or	or	CC
cord-256444-grw5s2pf	309	26	transcription	transcription	NN
cord-256444-grw5s2pf	309	27	complex	complex	NN
cord-256444-grw5s2pf	309	28	,	,	,
cord-256444-grw5s2pf	309	29	in	in	IN
cord-256444-grw5s2pf	309	30	view	view	NN
cord-256444-grw5s2pf	309	31	of	of	IN
cord-256444-grw5s2pf	309	32	the	the	DT
cord-256444-grw5s2pf	309	33	fact	fact	NN
cord-256444-grw5s2pf	309	34	that	that	IN
cord-256444-grw5s2pf	309	35	viral	viral	JJ
cord-256444-grw5s2pf	309	36	RNA	RNA	NNP
cord-256444-grw5s2pf	309	37	synthesis	synthesis	NN
cord-256444-grw5s2pf	309	38	occurs	occur	VBZ
cord-256444-grw5s2pf	309	39	in	in	IN
cord-256444-grw5s2pf	309	40	the	the	DT
cord-256444-grw5s2pf	309	41	membrane	membrane	NN
cord-256444-grw5s2pf	309	42	fraction	fraction	NN
cord-256444-grw5s2pf	309	43	of	of	IN
cord-256444-grw5s2pf	309	44	infected	infected	JJ
cord-256444-grw5s2pf	309	45	cells	cell	NNS
cord-256444-grw5s2pf	309	46	Dennis	Dennis	NNP
cord-256444-grw5s2pf	309	47	and	and	CC
cord-256444-grw5s2pf	309	48	Brian	Brian	NNP
cord-256444-grw5s2pf	309	49	,	,	,
cord-256444-grw5s2pf	309	50	1982	1982	CD
cord-256444-grw5s2pf	309	51	)	)	-RRB-
cord-256444-grw5s2pf	309	52	.	.	.
cord-256444-grw5s2pf	310	1	The	the	DT
cord-256444-grw5s2pf	310	2	three	three	CD
cord-256444-grw5s2pf	310	3	structural	structural	JJ
cord-256444-grw5s2pf	310	4	domains	domain	NNS
cord-256444-grw5s2pf	310	5	of	of	IN
cord-256444-grw5s2pf	310	6	the	the	DT
cord-256444-grw5s2pf	310	7	N	N	NNP
cord-256444-grw5s2pf	310	8	protein	protein	NN
cord-256444-grw5s2pf	310	9	are	be	VBP
cord-256444-grw5s2pf	310	10	separated	separate	VBN
cord-256444-grw5s2pf	310	11	by	by	IN
cord-256444-grw5s2pf	310	12	spacer	spacer	NN
cord-256444-grw5s2pf	310	13	regions	region	NNS
cord-256444-grw5s2pf	310	14	,	,	,
cord-256444-grw5s2pf	310	15	which	which	WDT
cord-256444-grw5s2pf	310	16	are	be	VBP
cord-256444-grw5s2pf	310	17	not	not	RB
cord-256444-grw5s2pf	310	18	conserved	conserve	VBN
cord-256444-grw5s2pf	310	19	(	(	-LRB-
cord-256444-grw5s2pf	310	20	Masters	master	NNS
cord-256444-grw5s2pf	310	21	,	,	,
cord-256444-grw5s2pf	310	22	1992	1992	CD
cord-256444-grw5s2pf	310	23	)	)	-RRB-
cord-256444-grw5s2pf	310	24	.	.	.
cord-256444-grw5s2pf	311	1	The	the	DT
cord-256444-grw5s2pf	311	2	functions	function	NNS
cord-256444-grw5s2pf	311	3	of	of	IN
cord-256444-grw5s2pf	311	4	the	the	DT
cord-256444-grw5s2pf	311	5	N	N	NNP
cord-256444-grw5s2pf	311	6	-	-	HYPH
cord-256444-grw5s2pf	311	7	and	and	CC
cord-256444-grw5s2pf	311	8	C	C	NNP
cord-256444-grw5s2pf	311	9	-	-	HYPH
cord-256444-grw5s2pf	311	10	terminal	terminal	NN
cord-256444-grw5s2pf	311	11	conserved	conserve	VBN
cord-256444-grw5s2pf	311	12	domains	domain	NNS
cord-256444-grw5s2pf	311	13	are	be	VBP
cord-256444-grw5s2pf	311	14	not	not	RB
cord-256444-grw5s2pf	311	15	yet	yet	RB
cord-256444-grw5s2pf	311	16	clear	clear	JJ
cord-256444-grw5s2pf	311	17	.	.	.
cord-256444-grw5s2pf	312	1	Using	use	VBG
cord-256444-grw5s2pf	312	2	a	a	DT
cord-256444-grw5s2pf	312	3	targeted	target	VBN
cord-256444-grw5s2pf	312	4	recombination	recombination	NN
cord-256444-grw5s2pf	312	5	approach	approach	NN
cord-256444-grw5s2pf	312	6	(	(	-LRB-
cord-256444-grw5s2pf	312	7	Koetzner	Koetzner	NNP
cord-256444-grw5s2pf	312	8	et	et	NNP
cord-256444-grw5s2pf	312	9	al	al	NNP
cord-256444-grw5s2pf	312	10	.	.	NNP
cord-256444-grw5s2pf	312	11	,	,	,
cord-256444-grw5s2pf	312	12	1992	1992	CD
cord-256444-grw5s2pf	312	13	;	;	:
cord-256444-grw5s2pf	312	14	Masters	Masters	NNPS
cord-256444-grw5s2pf	312	15	et	et	NNP
cord-256444-grw5s2pf	312	16	al	al	NNP
cord-256444-grw5s2pf	312	17	.	.	NNP
cord-256444-grw5s2pf	312	18	,	,	,
cord-256444-grw5s2pf	312	19	1994	1994	CD
cord-256444-grw5s2pf	312	20	)	)	-RRB-
cord-256444-grw5s2pf	312	21	to	to	TO
cord-256444-grw5s2pf	312	22	generate	generate	VB
cord-256444-grw5s2pf	312	23	recombinant	recombinant	JJ
cord-256444-grw5s2pf	312	24	viruses	virus	NNS
cord-256444-grw5s2pf	312	25	that	that	WDT
cord-256444-grw5s2pf	312	26	have	have	VBP
cord-256444-grw5s2pf	312	27	a	a	DT
cord-256444-grw5s2pf	312	28	chimeric	chimeric	JJ
cord-256444-grw5s2pf	312	29	N	n	CD
cord-256444-grw5s2pf	312	30	gene	gene	NN
cord-256444-grw5s2pf	312	31	containing	contain	VBG
cord-256444-grw5s2pf	312	32	parts	part	NNS
cord-256444-grw5s2pf	312	33	of	of	IN
cord-256444-grw5s2pf	312	34	BCV	BCV	NNP
cord-256444-grw5s2pf	312	35	and	and	CC
cord-256444-grw5s2pf	312	36	MHV	MHV	NNP
cord-256444-grw5s2pf	312	37	sequences	sequence	NNS
cord-256444-grw5s2pf	312	38	,	,	,
cord-256444-grw5s2pf	312	39	Peng	Peng	NNP
cord-256444-grw5s2pf	312	40	et	et	NNP
cord-256444-grw5s2pf	312	41	al	al	NNP
cord-256444-grw5s2pf	312	42	.	.	.
cord-256444-grw5s2pf	313	1	(	(	-LRB-
cord-256444-grw5s2pf	313	2	1995a	1995a	CD
cord-256444-grw5s2pf	313	3	)	)	-RRB-
cord-256444-grw5s2pf	313	4	have	have	VBP
cord-256444-grw5s2pf	313	5	shown	show	VBN
cord-256444-grw5s2pf	313	6	that	that	IN
cord-256444-grw5s2pf	313	7	there	there	EX
cord-256444-grw5s2pf	313	8	is	be	VBZ
cord-256444-grw5s2pf	313	9	strict	strict	JJ
cord-256444-grw5s2pf	313	10	sequence	sequence	NN
cord-256444-grw5s2pf	313	11	specificity	specificity	NN
cord-256444-grw5s2pf	313	12	within	within	IN
cord-256444-grw5s2pf	313	13	the	the	DT
cord-256444-grw5s2pf	313	14	conserved	conserved	JJ
cord-256444-grw5s2pf	313	15	structural	structural	JJ
cord-256444-grw5s2pf	313	16	domains	domain	NNS
cord-256444-grw5s2pf	313	17	for	for	IN
cord-256444-grw5s2pf	313	18	viable	viable	JJ
cord-256444-grw5s2pf	313	19	recombinants	recombinant	NNS
cord-256444-grw5s2pf	313	20	.	.	.
cord-256444-grw5s2pf	314	1	Since	since	IN
cord-256444-grw5s2pf	314	2	the	the	DT
cord-256444-grw5s2pf	314	3	N	N	NNP
cord-256444-grw5s2pf	314	4	protein	protein	NN
cord-256444-grw5s2pf	314	5	constitutes	constitute	VBZ
cord-256444-grw5s2pf	314	6	the	the	DT
cord-256444-grw5s2pf	314	7	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	314	8	,	,	,
cord-256444-grw5s2pf	314	9	mutations	mutation	NNS
cord-256444-grw5s2pf	314	10	within	within	IN
cord-256444-grw5s2pf	314	11	the	the	DT
cord-256444-grw5s2pf	314	12	N	N	NNP
cord-256444-grw5s2pf	314	13	protein	protein	NN
cord-256444-grw5s2pf	314	14	will	will	MD
cord-256444-grw5s2pf	314	15	likely	likely	RB
cord-256444-grw5s2pf	314	16	affect	affect	VB
cord-256444-grw5s2pf	314	17	the	the	DT
cord-256444-grw5s2pf	314	18	stability	stability	NN
cord-256444-grw5s2pf	314	19	or	or	CC
cord-256444-grw5s2pf	314	20	viability	viability	NN
cord-256444-grw5s2pf	314	21	of	of	IN
cord-256444-grw5s2pf	314	22	the	the	DT
cord-256444-grw5s2pf	314	23	virus	virus	NN
cord-256444-grw5s2pf	314	24	.	.	.
cord-256444-grw5s2pf	315	1	Indeed	indeed	RB
cord-256444-grw5s2pf	315	2	,	,	,
cord-256444-grw5s2pf	315	3	several	several	JJ
cord-256444-grw5s2pf	315	4	temperaturesensitive	temperaturesensitive	NN
cord-256444-grw5s2pf	315	5	and	and	CC
cord-256444-grw5s2pf	315	6	thermolabile	thermolabile	NN
cord-256444-grw5s2pf	315	7	mutants	mutant	NNS
cord-256444-grw5s2pf	315	8	of	of	IN
cord-256444-grw5s2pf	315	9	MHY	MHY	NNP
cord-256444-grw5s2pf	315	10	have	have	VBP
cord-256444-grw5s2pf	315	11	deletions	deletion	NNS
cord-256444-grw5s2pf	315	12	or	or	CC
cord-256444-grw5s2pf	315	13	mutations	mutation	NNS
cord-256444-grw5s2pf	315	14	within	within	IN
cord-256444-grw5s2pf	315	15	the	the	DT
cord-256444-grw5s2pf	315	16	N	N	NNP
cord-256444-grw5s2pf	315	17	protein	protein	NN
cord-256444-grw5s2pf	315	18	(	(	-LRB-
cord-256444-grw5s2pf	315	19	Koetzner	Koetzner	NNP
cord-256444-grw5s2pf	315	20	et	et	NNP
cord-256444-grw5s2pf	315	21	al	al	NNP
cord-256444-grw5s2pf	315	22	.	.	NNP
cord-256444-grw5s2pf	315	23	,	,	,
cord-256444-grw5s2pf	315	24	1992	1992	CD
cord-256444-grw5s2pf	315	25	;	;	:
cord-256444-grw5s2pf	315	26	Peng	Peng	NNP
cord-256444-grw5s2pf	315	27	et	et	NNP
cord-256444-grw5s2pf	315	28	al	al	NNP
cord-256444-grw5s2pf	315	29	.	.	.
cord-256444-grw5s2pf	316	1	,	,	,
cord-256444-grw5s2pf	316	2	1995b	1995b	CD
cord-256444-grw5s2pf	316	3	)	)	-RRB-
cord-256444-grw5s2pf	316	4	.	.	.
cord-256444-grw5s2pf	317	1	Viruses	virus	NNS
cord-256444-grw5s2pf	317	2	with	with	IN
cord-256444-grw5s2pf	317	3	site	site	NN
cord-256444-grw5s2pf	317	4	-	-	HYPH
cord-256444-grw5s2pf	317	5	specific	specific	JJ
cord-256444-grw5s2pf	317	6	mutations	mutation	NNS
cord-256444-grw5s2pf	317	7	of	of	IN
cord-256444-grw5s2pf	317	8	the	the	DT
cord-256444-grw5s2pf	317	9	N	n	CD
cord-256444-grw5s2pf	317	10	gene	gene	NN
cord-256444-grw5s2pf	317	11	have	have	VBP
cord-256444-grw5s2pf	317	12	been	be	VBN
cord-256444-grw5s2pf	317	13	generated	generate	VBN
cord-256444-grw5s2pf	317	14	by	by	IN
cord-256444-grw5s2pf	317	15	targeted	target	VBN
cord-256444-grw5s2pf	317	16	recombination	recombination	NN
cord-256444-grw5s2pf	317	17	techniques	technique	NNS
cord-256444-grw5s2pf	317	18	;	;	:
cord-256444-grw5s2pf	317	19	interestingly	interestingly	RB
cord-256444-grw5s2pf	317	20	,	,	,
cord-256444-grw5s2pf	317	21	revertants	revertant	NNS
cord-256444-grw5s2pf	317	22	of	of	IN
cord-256444-grw5s2pf	317	23	these	these	DT
cord-256444-grw5s2pf	317	24	mutants	mutant	NNS
cord-256444-grw5s2pf	317	25	often	often	RB
cord-256444-grw5s2pf	317	26	have	have	VBP
cord-256444-grw5s2pf	317	27	second	second	JJ
cord-256444-grw5s2pf	317	28	-	-	HYPH
cord-256444-grw5s2pf	317	29	site	site	NN
cord-256444-grw5s2pf	317	30	mutations	mutation	NNS
cord-256444-grw5s2pf	317	31	located	locate	VBD
cord-256444-grw5s2pf	317	32	a	a	DT
cord-256444-grw5s2pf	317	33	t	t	NN
cord-256444-grw5s2pf	317	34	different	different	JJ
cord-256444-grw5s2pf	317	35	domains	domain	NNS
cord-256444-grw5s2pf	317	36	,	,	,
cord-256444-grw5s2pf	317	37	suggesting	suggest	VBG
cord-256444-grw5s2pf	317	38	that	that	IN
cord-256444-grw5s2pf	317	39	there	there	EX
cord-256444-grw5s2pf	317	40	are	be	VBP
cord-256444-grw5s2pf	317	41	interactions	interaction	NNS
cord-256444-grw5s2pf	317	42	between	between	IN
cord-256444-grw5s2pf	317	43	different	different	JJ
cord-256444-grw5s2pf	317	44	domains	domain	NNS
cord-256444-grw5s2pf	317	45	of	of	IN
cord-256444-grw5s2pf	317	46	the	the	DT
cord-256444-grw5s2pf	317	47	N	N	NNP
cord-256444-grw5s2pf	317	48	protein	protein	NN
cord-256444-grw5s2pf	317	49	(	(	-LRB-
cord-256444-grw5s2pf	317	50	Peng	Peng	NNP
cord-256444-grw5s2pf	317	51	et	et	NNP
cord-256444-grw5s2pf	317	52	al	al	NNP
cord-256444-grw5s2pf	317	53	.	.	NNP
cord-256444-grw5s2pf	317	54	,	,	,
cord-256444-grw5s2pf	317	55	199513	199513	CD
cord-256444-grw5s2pf	317	56	)	)	-RRB-
cord-256444-grw5s2pf	317	57	.	.	.
cord-256444-grw5s2pf	318	1	The	the	DT
cord-256444-grw5s2pf	318	2	role	role	NN
cord-256444-grw5s2pf	318	3	of	of	IN
cord-256444-grw5s2pf	318	4	phosphorylation	phosphorylation	NN
cord-256444-grw5s2pf	318	5	in	in	IN
cord-256444-grw5s2pf	318	6	the	the	DT
cord-256444-grw5s2pf	318	7	N	N	NNP
cord-256444-grw5s2pf	318	8	protein	protein	NN
cord-256444-grw5s2pf	318	9	has	have	VBZ
cord-256444-grw5s2pf	318	10	not	not	RB
cord-256444-grw5s2pf	318	11	been	be	VBN
cord-256444-grw5s2pf	318	12	elucidated	elucidate	VBN
cord-256444-grw5s2pf	318	13	.	.	.
cord-256444-grw5s2pf	319	1	The	the	DT
cord-256444-grw5s2pf	319	2	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	319	3	contains	contain	VBZ
cord-256444-grw5s2pf	319	4	a	a	DT
cord-256444-grw5s2pf	319	5	positive	positive	JJ
cord-256444-grw5s2pf	319	6	-	-	HYPH
cord-256444-grw5s2pf	319	7	sense	sense	NN
cord-256444-grw5s2pf	319	8	,	,	,
cord-256444-grw5s2pf	319	9	single	single	RB
cord-256444-grw5s2pf	319	10	-	-	HYPH
cord-256444-grw5s2pf	319	11	stranded	strand	VBN
cord-256444-grw5s2pf	319	12	RNA	RNA	NNP
cord-256444-grw5s2pf	319	13	genome	genome	NN
cord-256444-grw5s2pf	319	14	,	,	,
cord-256444-grw5s2pf	319	15	which	which	WDT
cord-256444-grw5s2pf	319	16	is	be	VBZ
cord-256444-grw5s2pf	319	17	the	the	DT
cord-256444-grw5s2pf	319	18	largest	large	JJS
cord-256444-grw5s2pf	319	19	viral	viral	JJ
cord-256444-grw5s2pf	319	20	RNA	RNA	NNP
cord-256444-grw5s2pf	319	21	genome	genome	NN
cord-256444-grw5s2pf	319	22	known	know	VBN
cord-256444-grw5s2pf	319	23	,	,	,
cord-256444-grw5s2pf	319	24	ranging	range	VBG
cord-256444-grw5s2pf	319	25	from	from	IN
cord-256444-grw5s2pf	319	26	27.6	27.6	CD
cord-256444-grw5s2pf	319	27	to	to	IN
cord-256444-grw5s2pf	319	28	31	31	CD
cord-256444-grw5s2pf	319	29	kb	kb	NNS
cord-256444-grw5s2pf	319	30	.	.	.
cord-256444-grw5s2pf	320	1	The	the	DT
cord-256444-grw5s2pf	320	2	large	large	JJ
cord-256444-grw5s2pf	320	3	size	size	NN
cord-256444-grw5s2pf	320	4	of	of	IN
cord-256444-grw5s2pf	320	5	the	the	DT
cord-256444-grw5s2pf	320	6	viral	viral	JJ
cord-256444-grw5s2pf	320	7	RNA	RNA	NNP
cord-256444-grw5s2pf	320	8	requires	require	VBZ
cord-256444-grw5s2pf	320	9	the	the	DT
cord-256444-grw5s2pf	320	10	virus	virus	NN
cord-256444-grw5s2pf	320	11	to	to	TO
cord-256444-grw5s2pf	320	12	develop	develop	VB
cord-256444-grw5s2pf	320	13	special	special	JJ
cord-256444-grw5s2pf	320	14	mechanisms	mechanism	NNS
cord-256444-grw5s2pf	320	15	of	of	IN
cord-256444-grw5s2pf	320	16	RNA	RNA	NNP
cord-256444-grw5s2pf	320	17	synthesis	synthesis	NN
cord-256444-grw5s2pf	320	18	to	to	TO
cord-256444-grw5s2pf	320	19	counter	counter	VB
cord-256444-grw5s2pf	320	20	the	the	DT
cord-256444-grw5s2pf	320	21	deleterious	deleterious	JJ
cord-256444-grw5s2pf	320	22	effects	effect	NNS
cord-256444-grw5s2pf	320	23	of	of	IN
cord-256444-grw5s2pf	320	24	the	the	DT
cord-256444-grw5s2pf	320	25	possible	possible	JJ
cord-256444-grw5s2pf	320	26	errors	error	NNS
cord-256444-grw5s2pf	320	27	during	during	IN
cord-256444-grw5s2pf	320	28	RNA	RNA	NNP
cord-256444-grw5s2pf	320	29	synthesis	synthesis	NN
cord-256444-grw5s2pf	320	30	.	.	.
cord-256444-grw5s2pf	321	1	The	the	DT
cord-256444-grw5s2pf	321	2	virion	virion	NN
cord-256444-grw5s2pf	321	3	RNA	RNA	NNP
cord-256444-grw5s2pf	321	4	functions	function	NNS
cord-256444-grw5s2pf	321	5	as	as	IN
cord-256444-grw5s2pf	321	6	an	an	DT
cord-256444-grw5s2pf	321	7	mRNA	mrna	NN
cord-256444-grw5s2pf	321	8	and	and	CC
cord-256444-grw5s2pf	321	9	is	be	VBZ
cord-256444-grw5s2pf	321	10	infectious	infectious	JJ
cord-256444-grw5s2pf	321	11	.	.	.
cord-256444-grw5s2pf	322	1	It	-PRON-	PRP
cord-256444-grw5s2pf	322	2	contains	contain	VBZ
cord-256444-grw5s2pf	322	3	approximately	approximately	RB
cord-256444-grw5s2pf	322	4	7	7	CD
cord-256444-grw5s2pf	322	5	-	-	SYM
cord-256444-grw5s2pf	322	6	10	10	CD
cord-256444-grw5s2pf	322	7	functional	functional	JJ
cord-256444-grw5s2pf	322	8	genes	gene	NNS
cord-256444-grw5s2pf	322	9	,	,	,
cord-256444-grw5s2pf	322	10	4	4	CD
cord-256444-grw5s2pf	322	11	or	or	CC
cord-256444-grw5s2pf	322	12	5	5	CD
cord-256444-grw5s2pf	322	13	of	of	IN
cord-256444-grw5s2pf	322	14	which	which	WDT
cord-256444-grw5s2pf	322	15	encode	encode	VBP
cord-256444-grw5s2pf	322	16	structural	structural	JJ
cord-256444-grw5s2pf	322	17	proteins	protein	NNS
cord-256444-grw5s2pf	322	18	.	.	.
cord-256444-grw5s2pf	323	1	The	the	DT
cord-256444-grw5s2pf	323	2	genes	gene	NNS
cord-256444-grw5s2pf	323	3	are	be	VBP
cord-256444-grw5s2pf	323	4	arranged	arrange	VBN
cord-256444-grw5s2pf	323	5	in	in	IN
cord-256444-grw5s2pf	323	6	the	the	DT
cord-256444-grw5s2pf	323	7	order	order	NN
cord-256444-grw5s2pf	323	8	5'-polymerase-(HE)-S	5'-polymerase-(he)-s	CD
cord-256444-grw5s2pf	323	9	-	-	HYPH
cord-256444-grw5s2pf	323	10	E	e	NN
cord-256444-grw5s2pf	323	11	-	-	HYPH
cord-256444-grw5s2pf	323	12	M	M	NNP
cord-256444-grw5s2pf	323	13	-	-	HYPH
cord-256444-grw5s2pf	323	14	N-3	N-3	NNP
cord-256444-grw5s2pf	323	15	'	'	''
cord-256444-grw5s2pf	323	16	,	,	,
cord-256444-grw5s2pf	323	17	with	with	IN
cord-256444-grw5s2pf	323	18	a	a	DT
cord-256444-grw5s2pf	323	19	variable	variable	JJ
cord-256444-grw5s2pf	323	20	number	number	NN
cord-256444-grw5s2pf	323	21	of	of	IN
cord-256444-grw5s2pf	323	22	other	other	JJ
cord-256444-grw5s2pf	323	23	,	,	,
cord-256444-grw5s2pf	323	24	mostly	mostly	RB
cord-256444-grw5s2pf	323	25	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	323	26	and	and	CC
cord-256444-grw5s2pf	323	27	largely	largely	RB
cord-256444-grw5s2pf	323	28	nonessential	nonessential	JJ
cord-256444-grw5s2pf	323	29	,	,	,
cord-256444-grw5s2pf	323	30	genes	gene	NNS
cord-256444-grw5s2pf	323	31	interspersed	intersperse	VBN
cord-256444-grw5s2pf	323	32	among	among	IN
cord-256444-grw5s2pf	323	33	them	-PRON-	PRP
cord-256444-grw5s2pf	323	34	(	(	-LRB-
cord-256444-grw5s2pf	323	35	Fig	fig	NN
cord-256444-grw5s2pf	323	36	.	.	NNP
cord-256444-grw5s2pf	323	37	5	5	CD
cord-256444-grw5s2pf	323	38	)	)	-RRB-
cord-256444-grw5s2pf	323	39	.	.	.
cord-256444-grw5s2pf	324	1	This	this	DT
cord-256444-grw5s2pf	324	2	gene	gene	NN
cord-256444-grw5s2pf	324	3	arrangement	arrangement	NN
cord-256444-grw5s2pf	324	4	also	also	RB
cord-256444-grw5s2pf	324	5	applies	apply	VBZ
cord-256444-grw5s2pf	324	6	to	to	IN
cord-256444-grw5s2pf	324	7	toroviruses	toroviruse	NNS
cord-256444-grw5s2pf	324	8	and	and	CC
cord-256444-grw5s2pf	324	9	arteriviruses	arteriviruse	NNS
cord-256444-grw5s2pf	325	1	(	(	-LRB-
cord-256444-grw5s2pf	325	2	Fig	Fig	NNP
cord-256444-grw5s2pf	325	3	.	.	NNP
cord-256444-grw5s2pf	325	4	2	2	CD
cord-256444-grw5s2pf	325	5	)	)	-RRB-
cord-256444-grw5s2pf	325	6	.	.	.
cord-256444-grw5s2pf	326	1	The	the	DT
cord-256444-grw5s2pf	326	2	5	5	CD
cord-256444-grw5s2pf	326	3	'	'	POS
cord-256444-grw5s2pf	326	4	terminus	terminus	NN
cord-256444-grw5s2pf	326	5	of	of	IN
cord-256444-grw5s2pf	326	6	the	the	DT
cord-256444-grw5s2pf	326	7	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	326	8	genome	genome	NN
cord-256444-grw5s2pf	326	9	is	be	VBZ
cord-256444-grw5s2pf	326	10	capped	cap	VBN
cord-256444-grw5s2pf	326	11	,	,	,
cord-256444-grw5s2pf	326	12	and	and	CC
cord-256444-grw5s2pf	326	13	the	the	DT
cord-256444-grw5s2pf	326	14	RNA	RNA	NNP
cord-256444-grw5s2pf	326	15	starts	start	VBZ
cord-256444-grw5s2pf	326	16	with	with	IN
cord-256444-grw5s2pf	326	17	a	a	DT
cord-256444-grw5s2pf	326	18	leader	leader	NN
cord-256444-grw5s2pf	326	19	sequence	sequence	NN
cord-256444-grw5s2pf	326	20	of	of	IN
cord-256444-grw5s2pf	326	21	65	65	CD
cord-256444-grw5s2pf	326	22	-	-	SYM
cord-256444-grw5s2pf	326	23	98	98	CD
cord-256444-grw5s2pf	326	24	nucleotides	nucleotide	NNS
cord-256444-grw5s2pf	326	25	,	,	,
cord-256444-grw5s2pf	326	26	which	which	WDT
cord-256444-grw5s2pf	326	27	is	be	VBZ
cord-256444-grw5s2pf	326	28	also	also	RB
cord-256444-grw5s2pf	326	29	present	present	JJ
cord-256444-grw5s2pf	326	30	a	a	DT
cord-256444-grw5s2pf	326	31	t	t	NN
cord-256444-grw5s2pf	326	32	the	the	DT
cord-256444-grw5s2pf	326	33	5	5	CD
cord-256444-grw5s2pf	326	34	'	'	NN
cord-256444-grw5s2pf	326	35	end	end	NN
cord-256444-grw5s2pf	326	36	of	of	IN
cord-256444-grw5s2pf	326	37	mRNAs	mrnas	CD
cord-256444-grw5s2pf	326	38	,	,	,
cord-256444-grw5s2pf	326	39	followed	follow	VBN
cord-256444-grw5s2pf	326	40	by	by	IN
cord-256444-grw5s2pf	326	41	a	a	DT
cord-256444-grw5s2pf	326	42	200-to	200-to	CD
cord-256444-grw5s2pf	326	43	400-nucleotide	400-nucleotide	CD
cord-256444-grw5s2pf	326	44	untranslated	untranslated	JJ
cord-256444-grw5s2pf	326	45	region	region	NN
cord-256444-grw5s2pf	326	46	(	(	-LRB-
cord-256444-grw5s2pf	326	47	UTR	UTR	NNP
cord-256444-grw5s2pf	326	48	)	)	-RRB-
cord-256444-grw5s2pf	326	49	.	.	.
cord-256444-grw5s2pf	327	1	At	at	IN
cord-256444-grw5s2pf	327	2	the	the	DT
cord-256444-grw5s2pf	327	3	other	other	JJ
cord-256444-grw5s2pf	327	4	end	end	NN
cord-256444-grw5s2pf	327	5	of	of	IN
cord-256444-grw5s2pf	327	6	the	the	DT
cord-256444-grw5s2pf	327	7	genome	genome	NN
cord-256444-grw5s2pf	327	8	is	be	VBZ
cord-256444-grw5s2pf	327	9	a	a	DT
cord-256444-grw5s2pf	327	10	3	3	CD
cord-256444-grw5s2pf	327	11	'	'	''
cord-256444-grw5s2pf	327	12	UTR	UTR	NNP
cord-256444-grw5s2pf	327	13	of	of	IN
cord-256444-grw5s2pf	327	14	200	200	CD
cord-256444-grw5s2pf	327	15	-	-	SYM
cord-256444-grw5s2pf	327	16	500	500	CD
cord-256444-grw5s2pf	327	17	nucleotides	nucleotide	NNS
cord-256444-grw5s2pf	327	18	followed	follow	VBN
cord-256444-grw5s2pf	327	19	by	by	IN
cord-256444-grw5s2pf	327	20	a	a	DT
cord-256444-grw5s2pf	327	21	poly(A	poly(a	JJ
cord-256444-grw5s2pf	327	22	)	)	-RRB-
cord-256444-grw5s2pf	327	23	tail	tail	NN
cord-256444-grw5s2pf	327	24	.	.	.
cord-256444-grw5s2pf	328	1	Almost	almost	RB
cord-256444-grw5s2pf	328	2	two	two	CD
cord-256444-grw5s2pf	328	3	-	-	HYPH
cord-256444-grw5s2pf	328	4	thirds	third	NNS
cord-256444-grw5s2pf	328	5	of	of	IN
cord-256444-grw5s2pf	328	6	the	the	DT
cord-256444-grw5s2pf	328	7	entire	entire	JJ
cord-256444-grw5s2pf	328	8	RNA	RNA	NNP
cord-256444-grw5s2pf	328	9	is	be	VBZ
cord-256444-grw5s2pf	328	10	occupied	occupy	VBN
cord-256444-grw5s2pf	328	11	by	by	IN
cord-256444-grw5s2pf	328	12	the	the	DT
cord-256444-grw5s2pf	328	13	polymerase	polymerase	NN
cord-256444-grw5s2pf	328	14	gene	gene	NN
cord-256444-grw5s2pf	328	15	,	,	,
cord-256444-grw5s2pf	328	16	which	which	WDT
cord-256444-grw5s2pf	328	17	comprises	comprise	VBZ
cord-256444-grw5s2pf	328	18	two	two	CD
cord-256444-grw5s2pf	328	19	overlapping	overlap	VBG
cord-256444-grw5s2pf	328	20	ORFs	ORFs	NNP
cord-256444-grw5s2pf	328	21	,	,	,
cord-256444-grw5s2pf	328	22	la	la	NNP
cord-256444-grw5s2pf	328	23	and	and	CC
cord-256444-grw5s2pf	328	24	lb	lb	NN
cord-256444-grw5s2pf	328	25	.	.	.
cord-256444-grw5s2pf	329	1	At	at	IN
cord-256444-grw5s2pf	329	2	the	the	DT
cord-256444-grw5s2pf	329	3	overlap	overlap	NN
cord-256444-grw5s2pf	329	4	region	region	NN
cord-256444-grw5s2pf	329	5	is	be	VBZ
cord-256444-grw5s2pf	329	6	a	a	DT
cord-256444-grw5s2pf	329	7	specific	specific	JJ
cord-256444-grw5s2pf	329	8	seven	seven	CD
cord-256444-grw5s2pf	329	9	-	-	HYPH
cord-256444-grw5s2pf	329	10	nucleotide	nucleotide	JJ
cord-256444-grw5s2pf	329	11	"	"	``
cord-256444-grw5s2pf	329	12	slippery	slippery	JJ
cord-256444-grw5s2pf	329	13	"	"	''
cord-256444-grw5s2pf	329	14	sequence	sequence	NN
cord-256444-grw5s2pf	329	15	and	and	CC
cord-256444-grw5s2pf	329	16	a	a	DT
cord-256444-grw5s2pf	329	17	pseudoknot	pseudoknot	NN
cord-256444-grw5s2pf	329	18	structure	structure	NN
cord-256444-grw5s2pf	329	19	,	,	,
cord-256444-grw5s2pf	329	20	characteristic	characteristic	NN
cord-256444-grw5s2pf	329	21	of	of	IN
cord-256444-grw5s2pf	329	22	the	the	DT
cord-256444-grw5s2pf	329	23	ribosomal	ribosomal	JJ
cord-256444-grw5s2pf	329	24	frameshifting	frameshifte	VBG
cord-256444-grw5s2pf	329	25	signal	signal	NN
cord-256444-grw5s2pf	329	26	(	(	-LRB-
cord-256444-grw5s2pf	329	27	Brierley	Brierley	NNP
cord-256444-grw5s2pf	329	28	et	et	NNP
cord-256444-grw5s2pf	329	29	al	al	NNP
cord-256444-grw5s2pf	329	30	.	.	NNP
cord-256444-grw5s2pf	329	31	,	,	,
cord-256444-grw5s2pf	329	32	1987	1987	CD
cord-256444-grw5s2pf	329	33	(	(	-LRB-
cord-256444-grw5s2pf	329	34	Brierley	Brierley	NNP
cord-256444-grw5s2pf	329	35	et	et	NNP
cord-256444-grw5s2pf	329	36	al	al	NNP
cord-256444-grw5s2pf	329	37	.	.	NNP
cord-256444-grw5s2pf	329	38	,	,	,
cord-256444-grw5s2pf	329	39	,	,	,
cord-256444-grw5s2pf	329	40	1989	1989	CD
cord-256444-grw5s2pf	329	41	Lee	Lee	NNP
cord-256444-grw5s2pf	329	42	et	et	NNP
cord-256444-grw5s2pf	329	43	al	al	NNP
cord-256444-grw5s2pf	329	44	.	.	NNP
cord-256444-grw5s2pf	329	45	,	,	,
cord-256444-grw5s2pf	329	46	1991	1991	CD
cord-256444-grw5s2pf	329	47	;	;	:
cord-256444-grw5s2pf	329	48	,	,	,
cord-256444-grw5s2pf	329	49	which	which	WDT
cord-256444-grw5s2pf	329	50	is	be	VBZ
cord-256444-grw5s2pf	329	51	required	require	VBN
cord-256444-grw5s2pf	329	52	for	for	IN
cord-256444-grw5s2pf	329	53	the	the	DT
cord-256444-grw5s2pf	329	54	translation	translation	NN
cord-256444-grw5s2pf	329	55	of	of	IN
cord-256444-grw5s2pf	329	56	ORF	ORF	NNP
cord-256444-grw5s2pf	329	57	lb	lb	CD
cord-256444-grw5s2pf	329	58	.	.	.
cord-256444-grw5s2pf	330	1	The	the	DT
cord-256444-grw5s2pf	330	2	architecture	architecture	NN
cord-256444-grw5s2pf	330	3	of	of	IN
cord-256444-grw5s2pf	330	4	the	the	DT
cord-256444-grw5s2pf	330	5	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	330	6	protein	protein	NN
cord-256444-grw5s2pf	330	7	genes	gene	NNS
cord-256444-grw5s2pf	330	8	interspersed	intersperse	VBN
cord-256444-grw5s2pf	330	9	between	between	IN
cord-256444-grw5s2pf	330	10	the	the	DT
cord-256444-grw5s2pf	330	11	known	know	VBN
cord-256444-grw5s2pf	330	12	structural	structural	JJ
cord-256444-grw5s2pf	330	13	protein	protein	NN
cord-256444-grw5s2pf	330	14	genes	gene	NNS
cord-256444-grw5s2pf	330	15	varies	vary	VBZ
cord-256444-grw5s2pf	330	16	significantly	significantly	RB
cord-256444-grw5s2pf	330	17	among	among	IN
cord-256444-grw5s2pf	330	18	different	different	JJ
cord-256444-grw5s2pf	330	19	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	330	20	species	specie	NNS
cord-256444-grw5s2pf	330	21	(	(	-LRB-
cord-256444-grw5s2pf	330	22	Fig	fig	NN
cord-256444-grw5s2pf	330	23	.	.	.
cord-256444-grw5s2pf	330	24	5	5	CD
cord-256444-grw5s2pf	330	25	)	)	-RRB-
cord-256444-grw5s2pf	330	26	.	.	.
cord-256444-grw5s2pf	331	1	For	for	IN
cord-256444-grw5s2pf	331	2	example	example	NN
cord-256444-grw5s2pf	331	3	,	,	,
cord-256444-grw5s2pf	331	4	in	in	IN
cord-256444-grw5s2pf	331	5	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	331	6	,	,	,
cord-256444-grw5s2pf	331	7	gene	gene	NN
cord-256444-grw5s2pf	331	8	3	3	CD
cord-256444-grw5s2pf	331	9	contains	contain	VBZ
cord-256444-grw5s2pf	331	10	two	two	CD
cord-256444-grw5s2pf	331	11	ORFs	orf	NNS
cord-256444-grw5s2pf	331	12	,	,	,
cord-256444-grw5s2pf	331	13	whereas	whereas	IN
cord-256444-grw5s2pf	331	14	in	in	IN
cord-256444-grw5s2pf	331	15	the	the	DT
cord-256444-grw5s2pf	331	16	related	related	JJ
cord-256444-grw5s2pf	331	17	virus	virus	NN
cord-256444-grw5s2pf	331	18	PEDV	PEDV	NNP
cord-256444-grw5s2pf	331	19	these	these	DT
cord-256444-grw5s2pf	331	20	two	two	CD
cord-256444-grw5s2pf	331	21	ORFs	orf	NNS
cord-256444-grw5s2pf	331	22	are	be	VBP
cord-256444-grw5s2pf	331	23	fused	fuse	VBN
cord-256444-grw5s2pf	331	24	(	(	-LRB-
cord-256444-grw5s2pf	331	25	Duarte	Duarte	NNP
cord-256444-grw5s2pf	331	26	et	et	NNP
cord-256444-grw5s2pf	331	27	al	al	NNP
cord-256444-grw5s2pf	331	28	.	.	NNP
cord-256444-grw5s2pf	331	29	,	,	,
cord-256444-grw5s2pf	331	30	1994	1994	CD
cord-256444-grw5s2pf	331	31	)	)	-RRB-
cord-256444-grw5s2pf	331	32	.	.	.
cord-256444-grw5s2pf	332	1	In	in	IN
cord-256444-grw5s2pf	332	2	HCV	HCV	NNP
cord-256444-grw5s2pf	332	3	-	-	HYPH
cord-256444-grw5s2pf	332	4	OC43	OC43	NNP
cord-256444-grw5s2pf	332	5	,	,	,
cord-256444-grw5s2pf	332	6	gene	gene	NN
cord-256444-grw5s2pf	332	7	4	4	CD
cord-256444-grw5s2pf	332	8	is	be	VBZ
cord-256444-grw5s2pf	332	9	missing	miss	VBG
cord-256444-grw5s2pf	332	10	altogether	altogether	RB
cord-256444-grw5s2pf	332	11	(	(	-LRB-
cord-256444-grw5s2pf	332	12	Mounir	Mounir	NNP
cord-256444-grw5s2pf	332	13	and	and	CC
cord-256444-grw5s2pf	332	14	Talbot	Talbot	NNP
cord-256444-grw5s2pf	332	15	,	,	,
cord-256444-grw5s2pf	332	16	1993	1993	CD
cord-256444-grw5s2pf	332	17	)	)	-RRB-
cord-256444-grw5s2pf	332	18	.	.	.
cord-256444-grw5s2pf	333	1	Finally	finally	RB
cord-256444-grw5s2pf	333	2	,	,	,
cord-256444-grw5s2pf	333	3	in	in	IN
cord-256444-grw5s2pf	333	4	IBV	IBV	NNP
cord-256444-grw5s2pf	333	5	,	,	,
cord-256444-grw5s2pf	333	6	two	two	CD
cord-256444-grw5s2pf	333	7	ORFs	orf	NNS
cord-256444-grw5s2pf	333	8	are	be	VBP
cord-256444-grw5s2pf	333	9	inserted	insert	VBN
cord-256444-grw5s2pf	333	10	between	between	IN
cord-256444-grw5s2pf	333	11	M	M	NNP
cord-256444-grw5s2pf	333	12	and	and	CC
cord-256444-grw5s2pf	333	13	N	n	CD
cord-256444-grw5s2pf	333	14	genes	gene	NNS
cord-256444-grw5s2pf	333	15	.	.	.
cord-256444-grw5s2pf	334	1	The	the	DT
cord-256444-grw5s2pf	334	2	variability	variability	NN
cord-256444-grw5s2pf	334	3	of	of	IN
cord-256444-grw5s2pf	334	4	gene	gene	NN
cord-256444-grw5s2pf	334	5	structure	structure	NN
cord-256444-grw5s2pf	334	6	indicates	indicate	VBZ
cord-256444-grw5s2pf	334	7	the	the	DT
cord-256444-grw5s2pf	334	8	plasticity	plasticity	NN
cord-256444-grw5s2pf	334	9	of	of	IN
cord-256444-grw5s2pf	334	10	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	334	11	RNA	RNA	NNP
cord-256444-grw5s2pf	334	12	and	and	CC
cord-256444-grw5s2pf	334	13	the	the	DT
cord-256444-grw5s2pf	334	14	frequent	frequent	JJ
cord-256444-grw5s2pf	334	15	occurrence	occurrence	NN
cord-256444-grw5s2pf	334	16	of	of	IN
cord-256444-grw5s2pf	334	17	recombination	recombination	NN
cord-256444-grw5s2pf	334	18	and	and	CC
cord-256444-grw5s2pf	334	19	also	also	RB
cord-256444-grw5s2pf	334	20	suggests	suggest	VBZ
cord-256444-grw5s2pf	334	21	that	that	IN
cord-256444-grw5s2pf	334	22	there	there	EX
cord-256444-grw5s2pf	334	23	is	be	VBZ
cord-256444-grw5s2pf	334	24	no	no	DT
cord-256444-grw5s2pf	334	25	strong	strong	JJ
cord-256444-grw5s2pf	334	26	conservation	conservation	NN
cord-256444-grw5s2pf	334	27	pressure	pressure	NN
cord-256444-grw5s2pf	334	28	on	on	IN
cord-256444-grw5s2pf	334	29	these	these	DT
cord-256444-grw5s2pf	334	30	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	334	31	proteins	protein	NNS
cord-256444-grw5s2pf	334	32	.	.	.
cord-256444-grw5s2pf	335	1	There	there	EX
cord-256444-grw5s2pf	335	2	is	be	VBZ
cord-256444-grw5s2pf	335	3	a	a	DT
cord-256444-grw5s2pf	335	4	stretch	stretch	NN
cord-256444-grw5s2pf	335	5	of	of	IN
cord-256444-grw5s2pf	335	6	consensus	consensus	NN
cord-256444-grw5s2pf	335	7	sequence	sequence	NN
cord-256444-grw5s2pf	335	8	,	,	,
cord-256444-grw5s2pf	335	9	UCUAAAC	UCUAAAC	NNP
cord-256444-grw5s2pf	335	10	(	(	-LRB-
cord-256444-grw5s2pf	335	11	for	for	IN
cord-256444-grw5s2pf	335	12	MHV	MHV	NNP
cord-256444-grw5s2pf	335	13	)	)	-RRB-
cord-256444-grw5s2pf	335	14	,	,	,
cord-256444-grw5s2pf	335	15	or	or	CC
cord-256444-grw5s2pf	335	16	a	a	DT
cord-256444-grw5s2pf	335	17	related	related	JJ
cord-256444-grw5s2pf	335	18	BCV	BCV	NNP
cord-256444-grw5s2pf	335	19	(	(	-LRB-
cord-256444-grw5s2pf	335	20	HCV	HCV	NNP
cord-256444-grw5s2pf	335	21	-	-	HYPH
cord-256444-grw5s2pf	335	22	OC43	OC43	NNP
cord-256444-grw5s2pf	335	23	)	)	-RRB-
cord-256444-grw5s2pf	335	24	FIG	FIG	NNP
cord-256444-grw5s2pf	335	25	5	5	CD
cord-256444-grw5s2pf	335	26	.	.	.
cord-256444-grw5s2pf	336	1	Comparative	comparative	JJ
cord-256444-grw5s2pf	336	2	genome	genome	NN
cord-256444-grw5s2pf	336	3	structure	structure	NN
cord-256444-grw5s2pf	336	4	of	of	IN
cord-256444-grw5s2pf	336	5	the	the	DT
cord-256444-grw5s2pf	336	6	different	different	JJ
cord-256444-grw5s2pf	336	7	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	336	8	.	.	.
cord-256444-grw5s2pf	337	1	The	the	DT
cord-256444-grw5s2pf	337	2	complete	complete	JJ
cord-256444-grw5s2pf	337	3	sequences	sequence	NNS
cord-256444-grw5s2pf	337	4	are	be	VBP
cord-256444-grw5s2pf	337	5	available	available	JJ
cord-256444-grw5s2pf	337	6	for	for	IN
cord-256444-grw5s2pf	337	7	MHV	MHV	NNP
cord-256444-grw5s2pf	337	8	,	,	,
cord-256444-grw5s2pf	337	9	IBV	IBV	NNP
cord-256444-grw5s2pf	337	10	,	,	,
cord-256444-grw5s2pf	337	11	TGEV	TGEV	NNP
cord-256444-grw5s2pf	337	12	,	,	,
cord-256444-grw5s2pf	337	13	and	and	CC
cord-256444-grw5s2pf	337	14	HCV-229E.	HCV-229E.	NNP
cord-256444-grw5s2pf	338	1	The	the	DT
cord-256444-grw5s2pf	338	2	gene	gene	NN
cord-256444-grw5s2pf	338	3	1	1	CD
cord-256444-grw5s2pf	338	4	sequences	sequence	NNS
cord-256444-grw5s2pf	338	5	of	of	IN
cord-256444-grw5s2pf	338	6	the	the	DT
cord-256444-grw5s2pf	338	7	remaining	remain	VBG
cord-256444-grw5s2pf	338	8	viruses	virus	NNS
cord-256444-grw5s2pf	338	9	have	have	VBP
cord-256444-grw5s2pf	338	10	not	not	RB
cord-256444-grw5s2pf	338	11	been	be	VBN
cord-256444-grw5s2pf	338	12	completed	complete	VBN
cord-256444-grw5s2pf	338	13	.	.	.
cord-256444-grw5s2pf	339	1	Gene	gene	NN
cord-256444-grw5s2pf	339	2	1	1	CD
cord-256444-grw5s2pf	339	3	sequences	sequence	NNS
cord-256444-grw5s2pf	339	4	are	be	VBP
cord-256444-grw5s2pf	339	5	interrupted	interrupt	VBN
cord-256444-grw5s2pf	339	6	and	and	CC
cord-256444-grw5s2pf	339	7	shortened	shorten	VBN
cord-256444-grw5s2pf	339	8	to	to	TO
cord-256444-grw5s2pf	339	9	highlight	highlight	VB
cord-256444-grw5s2pf	339	10	the	the	DT
cord-256444-grw5s2pf	339	11	remaining	remain	VBG
cord-256444-grw5s2pf	339	12	genes	gene	NNS
cord-256444-grw5s2pf	339	13	.	.	.
cord-256444-grw5s2pf	340	1	The	the	DT
cord-256444-grw5s2pf	340	2	vertical	vertical	JJ
cord-256444-grw5s2pf	340	3	lines	line	NNS
cord-256444-grw5s2pf	340	4	represent	represent	VBP
cord-256444-grw5s2pf	340	5	mRNA	mRNA	NNP
cord-256444-grw5s2pf	340	6	start	start	VB
cord-256444-grw5s2pf	340	7	sites	site	NNS
cord-256444-grw5s2pf	340	8	;	;	:
cord-256444-grw5s2pf	340	9	thus	thus	RB
cord-256444-grw5s2pf	340	10	,	,	,
cord-256444-grw5s2pf	340	11	each	each	DT
cord-256444-grw5s2pf	340	12	region	region	NN
cord-256444-grw5s2pf	340	13	between	between	IN
cord-256444-grw5s2pf	340	14	two	two	CD
cord-256444-grw5s2pf	340	15	vertical	vertical	JJ
cord-256444-grw5s2pf	340	16	lines	line	NNS
cord-256444-grw5s2pf	340	17	represents	represent	VBZ
cord-256444-grw5s2pf	340	18	a	a	DT
cord-256444-grw5s2pf	340	19	separate	separate	JJ
cord-256444-grw5s2pf	340	20	gene	gene	NN
cord-256444-grw5s2pf	340	21	(	(	-LRB-
cord-256444-grw5s2pf	340	22	"	"	``
cord-256444-grw5s2pf	340	23	transcription	transcription	NN
cord-256444-grw5s2pf	340	24	unit	unit	NN
cord-256444-grw5s2pf	340	25	"	"	''
cord-256444-grw5s2pf	340	26	)	)	-RRB-
cord-256444-grw5s2pf	340	27	.	.	.
cord-256444-grw5s2pf	341	1	The	the	DT
cord-256444-grw5s2pf	341	2	structural	structural	JJ
cord-256444-grw5s2pf	341	3	protein	protein	NN
cord-256444-grw5s2pf	341	4	genes	gene	NNS
cord-256444-grw5s2pf	341	5	are	be	VBP
cord-256444-grw5s2pf	341	6	marked	mark	VBN
cord-256444-grw5s2pf	341	7	by	by	IN
cord-256444-grw5s2pf	341	8	various	various	JJ
cord-256444-grw5s2pf	341	9	symbols	symbol	NNS
cord-256444-grw5s2pf	341	10	,	,	,
cord-256444-grw5s2pf	341	11	and	and	CC
cord-256444-grw5s2pf	341	12	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	341	13	protein	protein	NN
cord-256444-grw5s2pf	341	14	genes	gene	NNS
cord-256444-grw5s2pf	341	15	are	be	VBP
cord-256444-grw5s2pf	341	16	represented	represent	VBN
cord-256444-grw5s2pf	341	17	by	by	IN
cord-256444-grw5s2pf	341	18	unfilled	unfilled	JJ
cord-256444-grw5s2pf	341	19	boxes	box	NNS
cord-256444-grw5s2pf	341	20	.	.	.
cord-256444-grw5s2pf	342	1	The	the	DT
cord-256444-grw5s2pf	342	2	gene	gene	NN
cord-256444-grw5s2pf	342	3	arrangements	arrangement	NNS
cord-256444-grw5s2pf	342	4	of	of	IN
cord-256444-grw5s2pf	342	5	ns	ns	NNP
cord-256444-grw5s2pf	342	6	protein	protein	NN
cord-256444-grw5s2pf	342	7	genes	gene	NNS
cord-256444-grw5s2pf	342	8	and	and	CC
cord-256444-grw5s2pf	342	9	E	e	NN
cord-256444-grw5s2pf	342	10	protein	protein	NN
cord-256444-grw5s2pf	342	11	gene	gene	NN
cord-256444-grw5s2pf	342	12	are	be	VBP
cord-256444-grw5s2pf	342	13	very	very	RB
cord-256444-grw5s2pf	342	14	heterogeneous	heterogeneous	JJ
cord-256444-grw5s2pf	342	15	in	in	IN
cord-256444-grw5s2pf	342	16	terms	term	NNS
cord-256444-grw5s2pf	342	17	of	of	IN
cord-256444-grw5s2pf	342	18	transcription	transcription	NN
cord-256444-grw5s2pf	342	19	unit	unit	NN
cord-256444-grw5s2pf	342	20	and	and	CC
cord-256444-grw5s2pf	342	21	the	the	DT
cord-256444-grw5s2pf	342	22	relative	relative	JJ
cord-256444-grw5s2pf	342	23	size	size	NN
cord-256444-grw5s2pf	342	24	and	and	CC
cord-256444-grw5s2pf	342	25	position	position	NN
cord-256444-grw5s2pf	342	26	among	among	IN
cord-256444-grw5s2pf	342	27	different	different	JJ
cord-256444-grw5s2pf	342	28	strains	strain	NNS
cord-256444-grw5s2pf	342	29	of	of	IN
cord-256444-grw5s2pf	342	30	the	the	DT
cord-256444-grw5s2pf	342	31	same	same	JJ
cord-256444-grw5s2pf	342	32	virus	virus	NN
cord-256444-grw5s2pf	342	33	species	specie	NNS
cord-256444-grw5s2pf	342	34	;	;	:
cord-256444-grw5s2pf	342	35	only	only	RB
cord-256444-grw5s2pf	342	36	the	the	DT
cord-256444-grw5s2pf	342	37	representative	representative	JJ
cord-256444-grw5s2pf	342	38	one	one	CD
cord-256444-grw5s2pf	342	39	is	be	VBZ
cord-256444-grw5s2pf	342	40	presented	present	VBN
cord-256444-grw5s2pf	342	41	.	.	.
cord-256444-grw5s2pf	343	1	The	the	DT
cord-256444-grw5s2pf	343	2	numbering	number	VBG
cord-256444-grw5s2pf	343	3	system	system	NN
cord-256444-grw5s2pf	343	4	for	for	IN
cord-256444-grw5s2pf	343	5	the	the	DT
cord-256444-grw5s2pf	343	6	genes	gene	NNS
cord-256444-grw5s2pf	343	7	of	of	IN
cord-256444-grw5s2pf	343	8	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	343	9	deviates	deviate	VBZ
cord-256444-grw5s2pf	343	10	from	from	IN
cord-256444-grw5s2pf	343	11	the	the	DT
cord-256444-grw5s2pf	343	12	published	publish	VBN
cord-256444-grw5s2pf	343	13	one	one	CD
cord-256444-grw5s2pf	343	14	to	to	TO
cord-256444-grw5s2pf	343	15	be	be	VB
cord-256444-grw5s2pf	343	16	consistent	consistent	JJ
cord-256444-grw5s2pf	343	17	with	with	IN
cord-256444-grw5s2pf	343	18	the	the	DT
cord-256444-grw5s2pf	343	19	other	other	JJ
cord-256444-grw5s2pf	343	20	viruses	virus	NNS
cord-256444-grw5s2pf	343	21	.	.	.
cord-256444-grw5s2pf	344	1	HCV	HCV	NNP
cord-256444-grw5s2pf	344	2	-	-	HYPH
cord-256444-grw5s2pf	344	3	OC43	OC43	NNP
cord-256444-grw5s2pf	344	4	does	do	VBZ
cord-256444-grw5s2pf	344	5	not	not	RB
cord-256444-grw5s2pf	344	6	have	have	VB
cord-256444-grw5s2pf	344	7	a	a	DT
cord-256444-grw5s2pf	344	8	gene	gene	NN
cord-256444-grw5s2pf	344	9	4	4	CD
cord-256444-grw5s2pf	344	10	.	.	.
cord-256444-grw5s2pf	344	11	sequence	sequence	NN
cord-256444-grw5s2pf	344	12	,	,	,
cord-256444-grw5s2pf	344	13	a	a	DT
cord-256444-grw5s2pf	344	14	t	t	NN
cord-256444-grw5s2pf	344	15	sites	site	NNS
cord-256444-grw5s2pf	344	16	immediately	immediately	RB
cord-256444-grw5s2pf	344	17	upstream	upstream	RB
cord-256444-grw5s2pf	344	18	of	of	IN
cord-256444-grw5s2pf	344	19	most	most	JJS
cord-256444-grw5s2pf	344	20	of	of	IN
cord-256444-grw5s2pf	344	21	the	the	DT
cord-256444-grw5s2pf	344	22	genes	gene	NNS
cord-256444-grw5s2pf	344	23	.	.	.
cord-256444-grw5s2pf	345	1	These	these	DT
cord-256444-grw5s2pf	345	2	sequences	sequence	NNS
cord-256444-grw5s2pf	345	3	represent	represent	VBP
cord-256444-grw5s2pf	345	4	signals	signal	NNS
cord-256444-grw5s2pf	345	5	for	for	IN
cord-256444-grw5s2pf	345	6	transcription	transcription	NN
cord-256444-grw5s2pf	345	7	of	of	IN
cord-256444-grw5s2pf	345	8	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	345	9	mRNAs	mRNAs	.
cord-256444-grw5s2pf	346	1	(	(	-LRB-
cord-256444-grw5s2pf	346	2	see	see	VB
cord-256444-grw5s2pf	346	3	Section	section	NN
cord-256444-grw5s2pf	346	4	V	v	NN
cord-256444-grw5s2pf	346	5	,	,	,
cord-256444-grw5s2pf	346	6	E	E	NNP
cord-256444-grw5s2pf	346	7	)	)	-RRB-
cord-256444-grw5s2pf	346	8	.	.	.
cord-256444-grw5s2pf	347	1	Finally	finally	RB
cord-256444-grw5s2pf	347	2	,	,	,
cord-256444-grw5s2pf	347	3	a	a	DT
cord-256444-grw5s2pf	347	4	pseudoknot	pseudoknot	NN
cord-256444-grw5s2pf	347	5	structure	structure	NN
cord-256444-grw5s2pf	347	6	has	have	VBZ
cord-256444-grw5s2pf	347	7	been	be	VBN
cord-256444-grw5s2pf	347	8	shown	show	VBN
cord-256444-grw5s2pf	347	9	to	to	TO
cord-256444-grw5s2pf	347	10	be	be	VB
cord-256444-grw5s2pf	347	11	present	present	JJ
cord-256444-grw5s2pf	348	1	a	a	DT
cord-256444-grw5s2pf	348	2	t	t	NN
cord-256444-grw5s2pf	348	3	the	the	DT
cord-256444-grw5s2pf	348	4	3	3	CD
cord-256444-grw5s2pf	348	5	'	'	''
cord-256444-grw5s2pf	348	6	end	end	NN
cord-256444-grw5s2pf	348	7	of	of	IN
cord-256444-grw5s2pf	348	8	the	the	DT
cord-256444-grw5s2pf	348	9	coronaviral	coronaviral	NNP
cord-256444-grw5s2pf	348	10	RNA	RNA	NNP
cord-256444-grw5s2pf	348	11	(	(	-LRB-
cord-256444-grw5s2pf	348	12	Williams	Williams	NNP
cord-256444-grw5s2pf	348	13	et	et	NNP
cord-256444-grw5s2pf	348	14	al	al	NNP
cord-256444-grw5s2pf	348	15	.	.	NNP
cord-256444-grw5s2pf	348	16	,	,	,
cord-256444-grw5s2pf	348	17	1995	1995	CD
cord-256444-grw5s2pf	348	18	)	)	-RRB-
cord-256444-grw5s2pf	348	19	.	.	.
cord-256444-grw5s2pf	349	1	A	a	DT
cord-256444-grw5s2pf	349	2	characteristic	characteristic	JJ
cord-256444-grw5s2pf	349	3	feature	feature	NN
cord-256444-grw5s2pf	349	4	of	of	IN
cord-256444-grw5s2pf	349	5	the	the	DT
cord-256444-grw5s2pf	349	6	Coronaviridae	Coronaviridae	NNP
cord-256444-grw5s2pf	349	7	,	,	,
cord-256444-grw5s2pf	349	8	and	and	CC
cord-256444-grw5s2pf	349	9	of	of	IN
cord-256444-grw5s2pf	349	10	the	the	DT
cord-256444-grw5s2pf	349	11	Arteriviridae	Arteriviridae	NNP
cord-256444-grw5s2pf	349	12	as	as	RB
cord-256444-grw5s2pf	349	13	well	well	RB
cord-256444-grw5s2pf	349	14	,	,	,
cord-256444-grw5s2pf	349	15	is	be	VBZ
cord-256444-grw5s2pf	349	16	that	that	IN
cord-256444-grw5s2pf	349	17	all	all	DT
cord-256444-grw5s2pf	349	18	known	know	VBN
cord-256444-grw5s2pf	349	19	member	member	NN
cord-256444-grw5s2pf	349	20	species	specie	NNS
cord-256444-grw5s2pf	349	21	generate	generate	VBP
cord-256444-grw5s2pf	349	22	a	a	DT
cord-256444-grw5s2pf	349	23	3'-coterminal	3'-coterminal	CD
cord-256444-grw5s2pf	349	24	nested	nested	JJ
cord-256444-grw5s2pf	349	25	set	set	NN
cord-256444-grw5s2pf	349	26	of	of	IN
cord-256444-grw5s2pf	349	27	five	five	CD
cord-256444-grw5s2pf	349	28	or	or	CC
cord-256444-grw5s2pf	349	29	more	more	JJR
cord-256444-grw5s2pf	349	30	mRNAs	mRNAs	.
cord-256444-grw5s2pf	349	31	(	(	-LRB-
cord-256444-grw5s2pf	349	32	see	see	VB
cord-256444-grw5s2pf	349	33	Fig	Fig	NNP
cord-256444-grw5s2pf	349	34	.	.	NNP
cord-256444-grw5s2pf	349	35	7	7	CD
cord-256444-grw5s2pf	349	36	)	)	-RRB-
cord-256444-grw5s2pf	349	37	.	.	.
cord-256444-grw5s2pf	350	1	Each	each	DT
cord-256444-grw5s2pf	350	2	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	350	3	and	and	CC
cord-256444-grw5s2pf	350	4	arterivirus	arterivirus	NNP
cord-256444-grw5s2pf	350	5	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	350	6	mRNA	mRNA	NNP
cord-256444-grw5s2pf	350	7	has	have	VBZ
cord-256444-grw5s2pf	350	8	the	the	DT
cord-256444-grw5s2pf	350	9	leader	leader	NN
cord-256444-grw5s2pf	350	10	sequence	sequence	VB
cord-256444-grw5s2pf	350	11	a	a	DT
cord-256444-grw5s2pf	350	12	t	t	NN
cord-256444-grw5s2pf	351	1	its	-PRON-	PRP$
cord-256444-grw5s2pf	351	2	5	5	CD
cord-256444-grw5s2pf	351	3	'	'	''
cord-256444-grw5s2pf	351	4	end	end	NN
cord-256444-grw5s2pf	351	5	.	.	.
cord-256444-grw5s2pf	352	1	Curiously	curiously	RB
cord-256444-grw5s2pf	352	2	,	,	,
cord-256444-grw5s2pf	352	3	no	no	DT
cord-256444-grw5s2pf	352	4	leader	leader	NN
cord-256444-grw5s2pf	352	5	RNA	RNA	NNP
cord-256444-grw5s2pf	352	6	sequence	sequence	NN
cord-256444-grw5s2pf	352	7	is	be	VBZ
cord-256444-grw5s2pf	352	8	present	present	JJ
cord-256444-grw5s2pf	352	9	in	in	IN
cord-256444-grw5s2pf	352	10	the	the	DT
cord-256444-grw5s2pf	352	11	torovirus	torovirus	NNP
cord-256444-grw5s2pf	352	12	RNAs	rna	NNS
cord-256444-grw5s2pf	352	13	(	(	-LRB-
cord-256444-grw5s2pf	352	14	Fig	Fig	NNP
cord-256444-grw5s2pf	352	15	.	.	NNP
cord-256444-grw5s2pf	352	16	2	2	CD
cord-256444-grw5s2pf	352	17	)	)	-RRB-
cord-256444-grw5s2pf	352	18	.	.	.
cord-256444-grw5s2pf	353	1	In	in	IN
cord-256444-grw5s2pf	353	2	1990	1990	CD
cord-256444-grw5s2pf	353	3	,	,	,
cord-256444-grw5s2pf	353	4	the	the	DT
cord-256444-grw5s2pf	353	5	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	353	6	Study	Study	NNP
cord-256444-grw5s2pf	353	7	Group	Group	NNP
cord-256444-grw5s2pf	353	8	published	publish	VBD
cord-256444-grw5s2pf	353	9	its	-PRON-	PRP$
cord-256444-grw5s2pf	353	10	recommendations	recommendation	NNS
cord-256444-grw5s2pf	353	11	for	for	IN
cord-256444-grw5s2pf	353	12	the	the	DT
cord-256444-grw5s2pf	353	13	nomenclature	nomenclature	NN
cord-256444-grw5s2pf	353	14	of	of	IN
cord-256444-grw5s2pf	353	15	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	353	16	genes	gene	NNS
cord-256444-grw5s2pf	353	17	,	,	,
cord-256444-grw5s2pf	353	18	mRNAs	mrnas	CD
cord-256444-grw5s2pf	353	19	,	,	,
cord-256444-grw5s2pf	353	20	and	and	CC
cord-256444-grw5s2pf	353	21	proteins	protein	NNS
cord-256444-grw5s2pf	353	22	(	(	-LRB-
cord-256444-grw5s2pf	353	23	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	353	24	et	et	NNP
cord-256444-grw5s2pf	353	25	al	al	NNP
cord-256444-grw5s2pf	353	26	.	.	NNP
cord-256444-grw5s2pf	353	27	,	,	,
cord-256444-grw5s2pf	353	28	1990	1990	CD
cord-256444-grw5s2pf	353	29	)	)	-RRB-
cord-256444-grw5s2pf	353	30	.	.	.
cord-256444-grw5s2pf	354	1	At	at	IN
cord-256444-grw5s2pf	354	2	that	that	DT
cord-256444-grw5s2pf	354	3	time	time	NN
cord-256444-grw5s2pf	354	4	it	-PRON-	PRP
cord-256444-grw5s2pf	354	5	was	be	VBD
cord-256444-grw5s2pf	354	6	reluctant	reluctant	JJ
cord-256444-grw5s2pf	354	7	to	to	TO
cord-256444-grw5s2pf	354	8	apply	apply	VB
cord-256444-grw5s2pf	354	9	the	the	DT
cord-256444-grw5s2pf	354	10	term	term	NN
cord-256444-grw5s2pf	354	11	"	"	``
cord-256444-grw5s2pf	354	12	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	354	13	"	"	''
cord-256444-grw5s2pf	354	14	t	t	NN
cord-256444-grw5s2pf	354	15	o	o	NN
cord-256444-grw5s2pf	354	16	the	the	DT
cord-256444-grw5s2pf	354	17	potential	potential	JJ
cord-256444-grw5s2pf	354	18	products	product	NNS
cord-256444-grw5s2pf	354	19	of	of	IN
cord-256444-grw5s2pf	354	20	genes	gene	NNS
cord-256444-grw5s2pf	354	21	which	which	WDT
cord-256444-grw5s2pf	354	22	were	be	VBD
cord-256444-grw5s2pf	354	23	suspected	suspect	VBN
cord-256444-grw5s2pf	354	24	of	of	IN
cord-256444-grw5s2pf	354	25	not	not	RB
cord-256444-grw5s2pf	354	26	being	be	VBG
cord-256444-grw5s2pf	354	27	structural	structural	JJ
cord-256444-grw5s2pf	354	28	proteins	protein	NNS
cord-256444-grw5s2pf	354	29	.	.	.
cord-256444-grw5s2pf	355	1	This	this	DT
cord-256444-grw5s2pf	355	2	caution	caution	NN
cord-256444-grw5s2pf	355	3	was	be	VBD
cord-256444-grw5s2pf	355	4	a	a	DT
cord-256444-grw5s2pf	355	5	consequence	consequence	NN
cord-256444-grw5s2pf	355	6	of	of	IN
cord-256444-grw5s2pf	355	7	our	-PRON-	PRP$
cord-256444-grw5s2pf	355	8	lack	lack	NN
cord-256444-grw5s2pf	355	9	of	of	IN
cord-256444-grw5s2pf	355	10	knowledge	knowledge	NN
cord-256444-grw5s2pf	355	11	of	of	IN
cord-256444-grw5s2pf	355	12	those	those	DT
cord-256444-grw5s2pf	355	13	gene	gene	NN
cord-256444-grw5s2pf	355	14	products	product	NNS
cord-256444-grw5s2pf	355	15	,	,	,
cord-256444-grw5s2pf	355	16	a	a	DT
cord-256444-grw5s2pf	355	17	situation	situation	NN
cord-256444-grw5s2pf	355	18	which	which	WDT
cord-256444-grw5s2pf	355	19	has	have	VBZ
cord-256444-grw5s2pf	355	20	improved	improve	VBN
cord-256444-grw5s2pf	355	21	greatly	greatly	RB
cord-256444-grw5s2pf	355	22	in	in	IN
cord-256444-grw5s2pf	355	23	the	the	DT
cord-256444-grw5s2pf	355	24	last	last	JJ
cord-256444-grw5s2pf	355	25	5	5	CD
cord-256444-grw5s2pf	355	26	years	year	NNS
cord-256444-grw5s2pf	355	27	or	or	CC
cord-256444-grw5s2pf	355	28	so	so	RB
cord-256444-grw5s2pf	355	29	.	.	.
cord-256444-grw5s2pf	356	1	This	this	DT
cord-256444-grw5s2pf	356	2	has	have	VBZ
cord-256444-grw5s2pf	356	3	resulted	result	VBN
cord-256444-grw5s2pf	356	4	in	in	IN
cord-256444-grw5s2pf	356	5	the	the	DT
cord-256444-grw5s2pf	356	6	term	term	NN
cord-256444-grw5s2pf	356	7	"	"	``
cord-256444-grw5s2pf	356	8	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	356	9	(	(	-LRB-
cord-256444-grw5s2pf	356	10	nsl	nsl	NNP
cord-256444-grw5s2pf	356	11	"	"	''
cord-256444-grw5s2pf	356	12	being	be	VBG
cord-256444-grw5s2pf	356	13	applied	apply	VBN
cord-256444-grw5s2pf	356	14	more	more	RBR
cord-256444-grw5s2pf	356	15	widely	widely	RB
cord-256444-grw5s2pf	356	16	to	to	IN
cord-256444-grw5s2pf	356	17	several	several	JJ
cord-256444-grw5s2pf	356	18	gene	gene	NN
cord-256444-grw5s2pf	356	19	products	product	NNS
cord-256444-grw5s2pf	356	20	.	.	.
cord-256444-grw5s2pf	357	1	Every	every	DT
cord-256444-grw5s2pf	357	2	gene	gene	NN
cord-256444-grw5s2pf	357	3	that	that	WDT
cord-256444-grw5s2pf	357	4	encodes	encode	VBZ
cord-256444-grw5s2pf	357	5	the	the	DT
cord-256444-grw5s2pf	357	6	ns	ns	NNP
cord-256444-grw5s2pf	357	7	proteins	protein	NNS
cord-256444-grw5s2pf	357	8	has	have	VBZ
cord-256444-grw5s2pf	357	9	been	be	VBN
cord-256444-grw5s2pf	357	10	deleted	delete	VBN
cord-256444-grw5s2pf	357	11	in	in	IN
cord-256444-grw5s2pf	357	12	a	a	DT
cord-256444-grw5s2pf	357	13	t	t	NN
cord-256444-grw5s2pf	357	14	least	least	JJS
cord-256444-grw5s2pf	357	15	some	some	DT
cord-256444-grw5s2pf	357	16	naturally	naturally	RB
cord-256444-grw5s2pf	357	17	occurring	occur	VBG
cord-256444-grw5s2pf	357	18	virus	virus	NN
cord-256444-grw5s2pf	357	19	isolates	isolate	NNS
cord-256444-grw5s2pf	357	20	;	;	:
cord-256444-grw5s2pf	357	21	thus	thus	RB
cord-256444-grw5s2pf	357	22	,	,	,
cord-256444-grw5s2pf	357	23	most	most	JJS
cord-256444-grw5s2pf	357	24	of	of	IN
cord-256444-grw5s2pf	357	25	the	the	DT
cord-256444-grw5s2pf	357	26	ns	ns	NNP
cord-256444-grw5s2pf	357	27	genes	gene	NNS
cord-256444-grw5s2pf	357	28	are	be	VBP
cord-256444-grw5s2pf	357	29	not	not	RB
cord-256444-grw5s2pf	357	30	essential	essential	JJ
cord-256444-grw5s2pf	357	31	for	for	IN
cord-256444-grw5s2pf	357	32	viral	viral	JJ
cord-256444-grw5s2pf	357	33	replication	replication	NN
cord-256444-grw5s2pf	357	34	.	.	.
cord-256444-grw5s2pf	358	1	However	however	RB
cord-256444-grw5s2pf	358	2	,	,	,
cord-256444-grw5s2pf	358	3	some	some	DT
cord-256444-grw5s2pf	358	4	of	of	IN
cord-256444-grw5s2pf	358	5	the	the	DT
cord-256444-grw5s2pf	358	6	ns	ns	NNP
cord-256444-grw5s2pf	358	7	proteins	protein	NNS
cord-256444-grw5s2pf	358	8	may	may	MD
cord-256444-grw5s2pf	358	9	play	play	VB
cord-256444-grw5s2pf	358	10	a	a	DT
cord-256444-grw5s2pf	358	11	role	role	NN
cord-256444-grw5s2pf	358	12	in	in	IN
cord-256444-grw5s2pf	358	13	viral	viral	JJ
cord-256444-grw5s2pf	358	14	tissue	tissue	NN
cord-256444-grw5s2pf	358	15	tropism	tropism	NN
cord-256444-grw5s2pf	358	16	or	or	CC
cord-256444-grw5s2pf	358	17	pathogenicity	pathogenicity	NN
cord-256444-grw5s2pf	358	18	.	.	.
cord-256444-grw5s2pf	359	1	The	the	DT
cord-256444-grw5s2pf	359	2	polymerase	polymerase	NN
cord-256444-grw5s2pf	359	3	is	be	VBZ
cord-256444-grw5s2pf	359	4	encoded	encode	VBN
cord-256444-grw5s2pf	359	5	by	by	IN
cord-256444-grw5s2pf	359	6	gene	gene	NN
cord-256444-grw5s2pf	359	7	1	1	CD
cord-256444-grw5s2pf	359	8	,	,	,
cord-256444-grw5s2pf	359	9	which	which	WDT
cord-256444-grw5s2pf	359	10	accounts	account	VBZ
cord-256444-grw5s2pf	359	11	for	for	IN
cord-256444-grw5s2pf	359	12	approximately	approximately	RB
cord-256444-grw5s2pf	359	13	two	two	CD
cord-256444-grw5s2pf	359	14	-	-	HYPH
cord-256444-grw5s2pf	359	15	thirds	third	NNS
cord-256444-grw5s2pf	359	16	of	of	IN
cord-256444-grw5s2pf	359	17	the	the	DT
cord-256444-grw5s2pf	359	18	genome	genome	NN
cord-256444-grw5s2pf	360	1	(	(	-LRB-
cord-256444-grw5s2pf	360	2	Fig	Fig	NNP
cord-256444-grw5s2pf	360	3	.	.	NNP
cord-256444-grw5s2pf	360	4	2	2	CD
cord-256444-grw5s2pf	360	5	)	)	-RRB-
cord-256444-grw5s2pf	360	6	.	.	.
cord-256444-grw5s2pf	361	1	The	the	DT
cord-256444-grw5s2pf	361	2	complete	complete	JJ
cord-256444-grw5s2pf	361	3	polymerase	polymerase	NN
cord-256444-grw5s2pf	361	4	gene	gene	NN
cord-256444-grw5s2pf	361	5	of	of	IN
cord-256444-grw5s2pf	361	6	four	four	CD
cord-256444-grw5s2pf	361	7	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	361	8	(	(	-LRB-
cord-256444-grw5s2pf	361	9	IBV	IBV	NNP
cord-256444-grw5s2pf	361	10	,	,	,
cord-256444-grw5s2pf	361	11	MHV	MHV	NNP
cord-256444-grw5s2pf	361	12	,	,	,
cord-256444-grw5s2pf	361	13	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	361	14	,	,	,
cord-256444-grw5s2pf	361	15	and	and	CC
cord-256444-grw5s2pf	361	16	TGEV	TGEV	NNP
cord-256444-grw5s2pf	361	17	)	)	-RRB-
cord-256444-grw5s2pf	361	18	covering	cover	VBG
cord-256444-grw5s2pf	361	19	each	each	DT
cord-256444-grw5s2pf	361	20	of	of	IN
cord-256444-grw5s2pf	361	21	the	the	DT
cord-256444-grw5s2pf	361	22	three	three	CD
cord-256444-grw5s2pf	361	23	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	361	24	groups	group	NNS
cord-256444-grw5s2pf	361	25	has	have	VBZ
cord-256444-grw5s2pf	361	26	been	be	VBN
cord-256444-grw5s2pf	361	27	sequenced	sequence	VBN
cord-256444-grw5s2pf	362	1	Lee	Lee	NNP
cord-256444-grw5s2pf	362	2	et	et	NNP
cord-256444-grw5s2pf	362	3	al	al	NNP
cord-256444-grw5s2pf	362	4	.	.	NNP
cord-256444-grw5s2pf	362	5	,	,	,
cord-256444-grw5s2pf	362	6	1991	1991	CD
cord-256444-grw5s2pf	362	7	;	;	:
cord-256444-grw5s2pf	362	8	Bonilla	Bonilla	NNP
cord-256444-grw5s2pf	362	9	et	et	NNP
cord-256444-grw5s2pf	362	10	al	al	NNP
cord-256444-grw5s2pf	362	11	.	.	.
cord-256444-grw5s2pf	363	1	,	,	,
cord-256444-grw5s2pf	363	2	1994	1994	CD
cord-256444-grw5s2pf	363	3	;	;	:
cord-256444-grw5s2pf	363	4	Eleouet	Eleouet	NNP
cord-256444-grw5s2pf	363	5	et	et	NNP
cord-256444-grw5s2pf	363	6	al	al	NNP
cord-256444-grw5s2pf	363	7	.	.	NNP
cord-256444-grw5s2pf	363	8	,	,	,
cord-256444-grw5s2pf	363	9	1995	1995	CD
cord-256444-grw5s2pf	363	10	)	)	-RRB-
cord-256444-grw5s2pf	363	11	.	.	.
cord-256444-grw5s2pf	364	1	Although	although	IN
cord-256444-grw5s2pf	364	2	the	the	DT
cord-256444-grw5s2pf	364	3	polymerase	polymerase	NN
cord-256444-grw5s2pf	364	4	genes	gene	NNS
cord-256444-grw5s2pf	364	5	vary	vary	VBP
cord-256444-grw5s2pf	364	6	in	in	IN
cord-256444-grw5s2pf	364	7	size	size	NN
cord-256444-grw5s2pf	364	8	from	from	IN
cord-256444-grw5s2pf	364	9	approximately	approximately	RB
cord-256444-grw5s2pf	364	10	18	18	CD
cord-256444-grw5s2pf	364	11	to	to	TO
cord-256444-grw5s2pf	364	12	22	22	CD
cord-256444-grw5s2pf	364	13	kb	kb	NNP
cord-256444-grw5s2pf	364	14	,	,	,
cord-256444-grw5s2pf	364	15	the	the	DT
cord-256444-grw5s2pf	364	16	encoded	encode	VBN
cord-256444-grw5s2pf	364	17	proteins	protein	NNS
cord-256444-grw5s2pf	364	18	have	have	VBP
cord-256444-grw5s2pf	364	19	many	many	JJ
cord-256444-grw5s2pf	364	20	structural	structural	JJ
cord-256444-grw5s2pf	364	21	features	feature	NNS
cord-256444-grw5s2pf	364	22	in	in	IN
cord-256444-grw5s2pf	364	23	common	common	JJ
cord-256444-grw5s2pf	364	24	.	.	.
cord-256444-grw5s2pf	365	1	The	the	DT
cord-256444-grw5s2pf	365	2	degree	degree	NN
cord-256444-grw5s2pf	365	3	of	of	IN
cord-256444-grw5s2pf	365	4	amino	amino	JJ
cord-256444-grw5s2pf	365	5	acid	acid	NN
cord-256444-grw5s2pf	365	6	identity	identity	NN
cord-256444-grw5s2pf	365	7	for	for	IN
cord-256444-grw5s2pf	365	8	this	this	DT
cord-256444-grw5s2pf	365	9	gene	gene	NN
cord-256444-grw5s2pf	365	10	product	product	NN
cord-256444-grw5s2pf	365	11	is	be	VBZ
cord-256444-grw5s2pf	365	12	greater	great	JJR
cord-256444-grw5s2pf	365	13	than	than	IN
cord-256444-grw5s2pf	365	14	is	be	VBZ
cord-256444-grw5s2pf	365	15	observed	observe	VBN
cord-256444-grw5s2pf	365	16	for	for	IN
cord-256444-grw5s2pf	365	17	any	any	DT
cord-256444-grw5s2pf	365	18	other	other	JJ
cord-256444-grw5s2pf	365	19	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	365	20	gene	gene	NN
cord-256444-grw5s2pf	365	21	product	product	NN
cord-256444-grw5s2pf	365	22	.	.	.
cord-256444-grw5s2pf	366	1	The	the	DT
cord-256444-grw5s2pf	366	2	polymerase	polymerase	NN
cord-256444-grw5s2pf	366	3	gene	gene	NN
cord-256444-grw5s2pf	366	4	is	be	VBZ
cord-256444-grw5s2pf	366	5	predicted	predict	VBN
cord-256444-grw5s2pf	366	6	to	to	TO
cord-256444-grw5s2pf	366	7	encode	encode	VB
cord-256444-grw5s2pf	366	8	a	a	DT
cord-256444-grw5s2pf	366	9	protein	protein	NN
cord-256444-grw5s2pf	366	10	of	of	IN
cord-256444-grw5s2pf	366	11	approximately	approximately	RB
cord-256444-grw5s2pf	366	12	740	740	CD
cord-256444-grw5s2pf	366	13	-	-	HYPH
cord-256444-grw5s2pf	366	14	800	800	CD
cord-256444-grw5s2pf	366	15	kDa	kDa	NNS
cord-256444-grw5s2pf	366	16	.	.	.
cord-256444-grw5s2pf	367	1	Proteins	protein	NNS
cord-256444-grw5s2pf	367	2	of	of	IN
cord-256444-grw5s2pf	367	3	this	this	DT
cord-256444-grw5s2pf	367	4	size	size	NN
cord-256444-grw5s2pf	367	5	have	have	VBP
cord-256444-grw5s2pf	367	6	not	not	RB
cord-256444-grw5s2pf	367	7	been	be	VBN
cord-256444-grw5s2pf	367	8	detected	detect	VBN
cord-256444-grw5s2pf	367	9	in	in	IN
cord-256444-grw5s2pf	367	10	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	367	11	-	-	HYPH
cord-256444-grw5s2pf	367	12	infected	infect	VBN
cord-256444-grw5s2pf	367	13	cells	cell	NNS
cord-256444-grw5s2pf	367	14	,	,	,
cord-256444-grw5s2pf	367	15	in	in	IN
cord-256444-grw5s2pf	367	16	part	part	NN
cord-256444-grw5s2pf	367	17	because	because	IN
cord-256444-grw5s2pf	367	18	of	of	IN
cord-256444-grw5s2pf	367	19	co	co	JJ
cord-256444-grw5s2pf	367	20	-	-	JJ
cord-256444-grw5s2pf	367	21	translational	translational	JJ
cord-256444-grw5s2pf	367	22	polypro	polypro	NNP
cord-256444-grw5s2pf	367	23	-	-	HYPH
cord-256444-grw5s2pf	367	24	tein	tein	NNP
cord-256444-grw5s2pf	367	25	processing	processing	NN
cord-256444-grw5s2pf	367	26	.	.	.
cord-256444-grw5s2pf	368	1	The	the	DT
cord-256444-grw5s2pf	368	2	pol	pol	NN
cord-256444-grw5s2pf	368	3	gene	gene	NN
cord-256444-grw5s2pf	368	4	encodes	encode	VBZ
cord-256444-grw5s2pf	368	5	two	two	CD
cord-256444-grw5s2pf	368	6	ORFs	orf	NNS
cord-256444-grw5s2pf	368	7	,	,	,
cord-256444-grw5s2pf	368	8	l	l	NNP
cord-256444-grw5s2pf	368	9	a	a	NNP
cord-256444-grw5s2pf	368	10	and	and	CC
cord-256444-grw5s2pf	368	11	lb	lb	NN
cord-256444-grw5s2pf	368	12	,	,	,
cord-256444-grw5s2pf	368	13	which	which	WDT
cord-256444-grw5s2pf	368	14	overlap	overlap	VBP
cord-256444-grw5s2pf	368	15	by	by	IN
cord-256444-grw5s2pf	368	16	a	a	DT
cord-256444-grw5s2pf	368	17	few	few	JJ
cord-256444-grw5s2pf	368	18	dozen	dozen	NN
cord-256444-grw5s2pf	368	19	nucleotides	nucleotide	NNS
cord-256444-grw5s2pf	368	20	(	(	-LRB-
cord-256444-grw5s2pf	368	21	Figs	fig	NNS
cord-256444-grw5s2pf	368	22	.	.	.
cord-256444-grw5s2pf	368	23	2	2	CD
cord-256444-grw5s2pf	368	24	and	and	CC
cord-256444-grw5s2pf	368	25	6	6	CD
cord-256444-grw5s2pf	368	26	)	)	-RRB-
cord-256444-grw5s2pf	368	27	.	.	.
cord-256444-grw5s2pf	369	1	The	the	DT
cord-256444-grw5s2pf	369	2	second	second	JJ
cord-256444-grw5s2pf	369	3	,	,	,
cord-256444-grw5s2pf	369	4	ORF	ORF	NNP
cord-256444-grw5s2pf	369	5	lb	lb	NN
cord-256444-grw5s2pf	369	6	,	,	,
cord-256444-grw5s2pf	369	7	is	be	VBZ
cord-256444-grw5s2pf	369	8	in	in	IN
cord-256444-grw5s2pf	369	9	the	the	DT
cord-256444-grw5s2pf	369	10	-1	-1	NN
cord-256444-grw5s2pf	369	11	reading	reading	NN
cord-256444-grw5s2pf	369	12	frame	frame	NN
cord-256444-grw5s2pf	369	13	with	with	IN
cord-256444-grw5s2pf	369	14	respect	respect	NN
cord-256444-grw5s2pf	369	15	to	to	IN
cord-256444-grw5s2pf	369	16	the	the	DT
cord-256444-grw5s2pf	369	17	upstream	upstream	JJ
cord-256444-grw5s2pf	369	18	ORF	ORF	NNP
cord-256444-grw5s2pf	369	19	l	l	NNP
cord-256444-grw5s2pf	369	20	a	a	NN
cord-256444-grw5s2pf	369	21	and	and	CC
cord-256444-grw5s2pf	369	22	is	be	VBZ
cord-256444-grw5s2pf	369	23	translated	translate	VBN
cord-256444-grw5s2pf	369	24	following	follow	VBG
cord-256444-grw5s2pf	369	25	ribosomal	ribosomal	JJ
cord-256444-grw5s2pf	369	26	frameshifting	frameshifte	VBG
cord-256444-grw5s2pf	369	27	in	in	IN
cord-256444-grw5s2pf	369	28	the	the	DT
cord-256444-grw5s2pf	369	29	overlap	overlap	NN
cord-256444-grw5s2pf	369	30	region	region	NN
cord-256444-grw5s2pf	369	31	.	.	.
cord-256444-grw5s2pf	370	1	This	this	DT
cord-256444-grw5s2pf	370	2	will	will	MD
cord-256444-grw5s2pf	370	3	be	be	VB
cord-256444-grw5s2pf	370	4	examined	examine	VBN
cord-256444-grw5s2pf	370	5	in	in	IN
cord-256444-grw5s2pf	370	6	more	more	JJR
cord-256444-grw5s2pf	370	7	detail	detail	NN
cord-256444-grw5s2pf	370	8	in	in	IN
cord-256444-grw5s2pf	370	9	Section	section	NN
cord-256444-grw5s2pf	370	10	V	v	NN
cord-256444-grw5s2pf	370	11	,	,	,
cord-256444-grw5s2pf	371	1	G.	G.	NNP
cord-256444-grw5s2pf	371	2	There	there	EX
cord-256444-grw5s2pf	371	3	is	be	VBZ
cord-256444-grw5s2pf	371	4	greater	great	JJR
cord-256444-grw5s2pf	371	5	amino	amino	NN
cord-256444-grw5s2pf	371	6	acid	acid	NN
cord-256444-grw5s2pf	371	7	identity	identity	NN
cord-256444-grw5s2pf	371	8	among	among	IN
cord-256444-grw5s2pf	371	9	the	the	DT
cord-256444-grw5s2pf	371	10	l	l	NN
cord-256444-grw5s2pf	371	11	b	b	NNP
cord-256444-grw5s2pf	371	12	than	than	IN
cord-256444-grw5s2pf	371	13	the	the	DT
cord-256444-grw5s2pf	371	14	l	l	NN
cord-256444-grw5s2pf	371	15	a	a	DT
cord-256444-grw5s2pf	371	16	ORFs	ORFs	NNP
cord-256444-grw5s2pf	371	17	.	.	.
cord-256444-grw5s2pf	372	1	For	for	IN
cord-256444-grw5s2pf	372	2	example	example	NN
cord-256444-grw5s2pf	372	3	,	,	,
cord-256444-grw5s2pf	372	4	l	l	NNP
cord-256444-grw5s2pf	372	5	a	a	NNP
cord-256444-grw5s2pf	372	6	and	and	CC
cord-256444-grw5s2pf	372	7	l	l	NN
cord-256444-grw5s2pf	372	8	b	b	NNP
cord-256444-grw5s2pf	372	9	of	of	IN
cord-256444-grw5s2pf	372	10	IBV	IBV	NNP
cord-256444-grw5s2pf	372	11	,	,	,
cord-256444-grw5s2pf	372	12	the	the	DT
cord-256444-grw5s2pf	372	13	least	least	JJS
cord-256444-grw5s2pf	372	14	typical	typical	JJ
cord-256444-grw5s2pf	372	15	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	372	16	in	in	IN
cord-256444-grw5s2pf	372	17	terms	term	NNS
cord-256444-grw5s2pf	372	18	of	of	IN
cord-256444-grw5s2pf	372	19	protein	protein	NN
cord-256444-grw5s2pf	372	20	sequences	sequence	NNS
cord-256444-grw5s2pf	372	21	,	,	,
cord-256444-grw5s2pf	372	22	have	have	VBP
cord-256444-grw5s2pf	372	23	amino	amino	NN
cord-256444-grw5s2pf	372	24	acid	acid	JJ
cord-256444-grw5s2pf	372	25	identityhimilarity	identityhimilarity	NN
cord-256444-grw5s2pf	372	26	of	of	IN
cord-256444-grw5s2pf	372	27	approximately	approximately	RB
cord-256444-grw5s2pf	372	28	30/50	30/50	CD
cord-256444-grw5s2pf	372	29	%	%	NN
cord-256444-grw5s2pf	372	30	and	and	CC
cord-256444-grw5s2pf	372	31	55/79	55/79	CD
cord-256444-grw5s2pf	372	32	%	%	NN
cord-256444-grw5s2pf	372	33	,	,	,
cord-256444-grw5s2pf	372	34	respectively	respectively	RB
cord-256444-grw5s2pf	372	35	,	,	,
cord-256444-grw5s2pf	372	36	compared	compare	VBN
cord-256444-grw5s2pf	372	37	with	with	IN
cord-256444-grw5s2pf	372	38	those	those	DT
cord-256444-grw5s2pf	372	39	of	of	IN
cord-256444-grw5s2pf	372	40	MHV	MHV	NNP
cord-256444-grw5s2pf	372	41	,	,	,
cord-256444-grw5s2pf	372	42	HCV	HCV	NNP
cord-256444-grw5s2pf	372	43	,	,	,
cord-256444-grw5s2pf	372	44	and	and	CC
cord-256444-grw5s2pf	372	45	TGEV	TGEV	NNP
cord-256444-grw5s2pf	372	46	.	.	.
cord-256444-grw5s2pf	373	1	It	-PRON-	PRP
cord-256444-grw5s2pf	373	2	is	be	VBZ
cord-256444-grw5s2pf	373	3	the	the	DT
cord-256444-grw5s2pf	373	4	l	l	NNP
cord-256444-grw5s2pf	373	5	a	a	DT
cord-256444-grw5s2pf	373	6	ORF	ORF	NNP
cord-256444-grw5s2pf	373	7	which	which	WDT
cord-256444-grw5s2pf	373	8	accounts	account	VBZ
cord-256444-grw5s2pf	373	9	for	for	IN
cord-256444-grw5s2pf	373	10	the	the	DT
cord-256444-grw5s2pf	373	11	MHV	MHV	NNP
cord-256444-grw5s2pf	373	12	polymerase	polymerase	NN
cord-256444-grw5s2pf	373	13	gene	gene	NN
cord-256444-grw5s2pf	373	14	being	be	VBG
cord-256444-grw5s2pf	373	15	approximately	approximately	RB
cord-256444-grw5s2pf	373	16	1	1	CD
cord-256444-grw5s2pf	373	17	-	-	SYM
cord-256444-grw5s2pf	373	18	2	2	CD
cord-256444-grw5s2pf	373	19	kb	kb	NNP
cord-256444-grw5s2pf	373	20	longer	long	RBR
cord-256444-grw5s2pf	373	21	than	than	IN
cord-256444-grw5s2pf	373	22	those	those	DT
cord-256444-grw5s2pf	373	23	of	of	IN
cord-256444-grw5s2pf	373	24	IBV	IBV	NNP
cord-256444-grw5s2pf	373	25	,	,	,
cord-256444-grw5s2pf	373	26	HCV	HCV	NNP
cord-256444-grw5s2pf	373	27	,	,	,
cord-256444-grw5s2pf	373	28	and	and	CC
cord-256444-grw5s2pf	373	29	TGEV	TGEV	NNP
cord-256444-grw5s2pf	373	30	.	.	.
cord-256444-grw5s2pf	374	1	A	a	DT
cord-256444-grw5s2pf	374	2	number	number	NN
cord-256444-grw5s2pf	374	3	of	of	IN
cord-256444-grw5s2pf	374	4	functional	functional	JJ
cord-256444-grw5s2pf	374	5	domains	domain	NNS
cord-256444-grw5s2pf	374	6	within	within	IN
cord-256444-grw5s2pf	374	7	pol	pol	NN
cord-256444-grw5s2pf	374	8	have	have	VBP
cord-256444-grw5s2pf	374	9	been	be	VBN
cord-256444-grw5s2pf	374	10	predicted	predict	VBN
cord-256444-grw5s2pf	374	11	following	follow	VBG
cord-256444-grw5s2pf	374	12	computer	computer	NN
cord-256444-grw5s2pf	374	13	-	-	HYPH
cord-256444-grw5s2pf	374	14	based	base	VBN
cord-256444-grw5s2pf	374	15	motif	motif	NN
cord-256444-grw5s2pf	374	16	analyses	analysis	NNS
cord-256444-grw5s2pf	375	1	Hodgman	Hodgman	NNP
cord-256444-grw5s2pf	375	2	,	,	,
cord-256444-grw5s2pf	375	3	1988	1988	CD
cord-256444-grw5s2pf	375	4	;	;	:
cord-256444-grw5s2pf	375	5	Gorbalenya	Gorbalenya	NNP
cord-256444-grw5s2pf	375	6	et	et	NNP
cord-256444-grw5s2pf	375	7	al	al	NNP
cord-256444-grw5s2pf	375	8	.	.	NNP
cord-256444-grw5s2pf	375	9	,	,	,
cord-256444-grw5s2pf	375	10	1989a	1989a	CD
cord-256444-grw5s2pf	375	11	,	,	,
cord-256444-grw5s2pf	375	12	b	b	LS
cord-256444-grw5s2pf	375	13	;	;	:
cord-256444-grw5s2pf	375	14	Lee	Lee	NNP
cord-256444-grw5s2pf	375	15	et	et	NNP
cord-256444-grw5s2pf	375	16	al	al	NNP
cord-256444-grw5s2pf	375	17	.	.	NNP
cord-256444-grw5s2pf	375	18	,	,	,
cord-256444-grw5s2pf	375	19	1991	1991	CD
cord-256444-grw5s2pf	375	20	)	)	-RRB-
cord-256444-grw5s2pf	375	21	;	;	:
cord-256444-grw5s2pf	375	22	some	some	DT
cord-256444-grw5s2pf	375	23	of	of	IN
cord-256444-grw5s2pf	375	24	these	these	DT
cord-256444-grw5s2pf	375	25	functional	functional	JJ
cord-256444-grw5s2pf	375	26	domains	domain	NNS
cord-256444-grw5s2pf	375	27	have	have	VBP
cord-256444-grw5s2pf	375	28	been	be	VBN
cord-256444-grw5s2pf	375	29	confirmed	confirm	VBN
cord-256444-grw5s2pf	375	30	by	by	IN
cord-256444-grw5s2pf	375	31	experimental	experimental	JJ
cord-256444-grw5s2pf	375	32	analysis	analysis	NN
cord-256444-grw5s2pf	375	33	.	.	.
cord-256444-grw5s2pf	376	1	The	the	DT
cord-256444-grw5s2pf	376	2	location	location	NN
cord-256444-grw5s2pf	376	3	of	of	IN
cord-256444-grw5s2pf	376	4	these	these	DT
cord-256444-grw5s2pf	376	5	motifs	motif	NNS
cord-256444-grw5s2pf	376	6	is	be	VBZ
cord-256444-grw5s2pf	376	7	illustrated	illustrate	VBN
cord-256444-grw5s2pf	376	8	in	in	IN
cord-256444-grw5s2pf	376	9	Fig	Fig	NNP
cord-256444-grw5s2pf	376	10	.	.	.
cord-256444-grw5s2pf	377	1	6	6	LS
cord-256444-grw5s2pf	377	2	.	.	.
cord-256444-grw5s2pf	378	1	Three	three	CD
cord-256444-grw5s2pf	378	2	motifs	motif	NNS
cord-256444-grw5s2pf	378	3	have	have	VBP
cord-256444-grw5s2pf	378	4	been	be	VBN
cord-256444-grw5s2pf	378	5	identified	identify	VBN
cord-256444-grw5s2pf	378	6	in	in	IN
cord-256444-grw5s2pf	378	7	ORF	ORF	NNP
cord-256444-grw5s2pf	378	8	l	l	NNP
cord-256444-grw5s2pf	378	9	a	a	NNP
cord-256444-grw5s2pf	378	10	,	,	,
cord-256444-grw5s2pf	378	11	indicating	indicate	VBG
cord-256444-grw5s2pf	378	12	the	the	DT
cord-256444-grw5s2pf	378	13	presence	presence	NN
cord-256444-grw5s2pf	378	14	of	of	IN
cord-256444-grw5s2pf	378	15	one	one	CD
cord-256444-grw5s2pf	378	16	or	or	CC
cord-256444-grw5s2pf	378	17	two	two	CD
cord-256444-grw5s2pf	378	18	papain	papain	NN
cord-256444-grw5s2pf	378	19	-	-	HYPH
cord-256444-grw5s2pf	378	20	like	like	JJ
cord-256444-grw5s2pf	378	21	cysteine	cysteine	NN
cord-256444-grw5s2pf	378	22	proteases	protease	NNS
cord-256444-grw5s2pf	378	23	(	(	-LRB-
cord-256444-grw5s2pf	378	24	PLP	PLP	NNP
cord-256444-grw5s2pf	378	25	)	)	-RRB-
cord-256444-grw5s2pf	378	26	:	:	:
cord-256444-grw5s2pf	378	27	a	a	DT
cord-256444-grw5s2pf	378	28	chymotrypsinlpicornaviral3C	chymotrypsinlpicornaviral3c	CD
cord-256444-grw5s2pf	378	29	-	-	HYPH
cord-256444-grw5s2pf	378	30	like	like	JJ
cord-256444-grw5s2pf	378	31	protease	protease	NN
cord-256444-grw5s2pf	378	32	(	(	-LRB-
cord-256444-grw5s2pf	378	33	Lee	Lee	NNP
cord-256444-grw5s2pf	378	34	et	et	NNP
cord-256444-grw5s2pf	378	35	al	al	NNP
cord-256444-grw5s2pf	378	36	.	.	NNP
cord-256444-grw5s2pf	378	37	,	,	,
cord-256444-grw5s2pf	378	38	1991	1991	CD
cord-256444-grw5s2pf	378	39	)	)	-RRB-
cord-256444-grw5s2pf	378	40	.	.	.
cord-256444-grw5s2pf	379	1	(	(	-LRB-
cord-256444-grw5s2pf	379	2	a	a	LS
cord-256444-grw5s2pf	379	3	)	)	-RRB-
cord-256444-grw5s2pf	380	1	The	the	DT
cord-256444-grw5s2pf	380	2	polymerase	polymerase	NN
cord-256444-grw5s2pf	380	3	gene	gene	NN
cord-256444-grw5s2pf	380	4	comprises	comprise	VBZ
cord-256444-grw5s2pf	380	5	two	two	CD
cord-256444-grw5s2pf	380	6	ORFs	orf	NNS
cord-256444-grw5s2pf	380	7	,	,	,
cord-256444-grw5s2pf	380	8	l	l	NNP
cord-256444-grw5s2pf	380	9	a	a	NNP
cord-256444-grw5s2pf	380	10	and	and	CC
cord-256444-grw5s2pf	380	11	lb	lb	NN
cord-256444-grw5s2pf	380	12	,	,	,
cord-256444-grw5s2pf	380	13	which	which	WDT
cord-256444-grw5s2pf	380	14	overlap	overlap	VBP
cord-256444-grw5s2pf	380	15	,	,	,
cord-256444-grw5s2pf	380	16	the	the	DT
cord-256444-grw5s2pf	380	17	l	l	NNP
cord-256444-grw5s2pf	380	18	b	b	NNP
cord-256444-grw5s2pf	380	19	ORF	ORF	NNP
cord-256444-grw5s2pf	380	20	being	be	VBG
cord-256444-grw5s2pf	380	21	translated	translate	VBN
cord-256444-grw5s2pf	380	22	after	after	IN
cord-256444-grw5s2pf	380	23	ribosomal	ribosomal	JJ
cord-256444-grw5s2pf	380	24	frameshifting	frameshifting	NN
cord-256444-grw5s2pf	380	25	.	.	.
cord-256444-grw5s2pf	381	1	(	(	-LRB-
cord-256444-grw5s2pf	381	2	b	b	NN
cord-256444-grw5s2pf	381	3	)	)	-RRB-
cord-256444-grw5s2pf	382	1	The	the	DT
cord-256444-grw5s2pf	382	2	positions	position	NNS
cord-256444-grw5s2pf	382	3	of	of	IN
cord-256444-grw5s2pf	382	4	motifs	motif	NNS
cord-256444-grw5s2pf	382	5	:	:	:
cord-256444-grw5s2pf	382	6	PLP	PLP	NNP
cord-256444-grw5s2pf	382	7	1	1	CD
cord-256444-grw5s2pf	382	8	and	and	CC
cord-256444-grw5s2pf	382	9	2	2	CD
cord-256444-grw5s2pf	382	10	,	,	,
cord-256444-grw5s2pf	382	11	papain	papain	NN
cord-256444-grw5s2pf	382	12	-	-	HYPH
cord-256444-grw5s2pf	382	13	like	like	JJ
cord-256444-grw5s2pf	382	14	protease	protease	NN
cord-256444-grw5s2pf	382	15	;	;	:
cord-256444-grw5s2pf	382	16	X	x	NN
cord-256444-grw5s2pf	382	17	domain	domain	NN
cord-256444-grw5s2pf	382	18	,	,	,
cord-256444-grw5s2pf	382	19	highly	highly	RB
cord-256444-grw5s2pf	382	20	conserved	conserve	VBN
cord-256444-grw5s2pf	382	21	between	between	IN
cord-256444-grw5s2pf	382	22	IBV	IBV	NNP
cord-256444-grw5s2pf	382	23	and	and	CC
cord-256444-grw5s2pf	382	24	MHV	MHV	NNP
cord-256444-grw5s2pf	382	25	;	;	:
cord-256444-grw5s2pf	382	26	3CLP	3clp	LS
cord-256444-grw5s2pf	382	27	,	,	,
cord-256444-grw5s2pf	382	28	picornavirus-3C	picornavirus-3C	VBN
cord-256444-grw5s2pf	382	29	-	-	HYPH
cord-256444-grw5s2pf	382	30	like	like	JJ
cord-256444-grw5s2pf	382	31	protease	protease	NN
cord-256444-grw5s2pf	382	32	;	;	:
cord-256444-grw5s2pf	382	33	MD	MD	NNP
cord-256444-grw5s2pf	382	34	,	,	,
cord-256444-grw5s2pf	382	35	membrane	membrane	NN
cord-256444-grw5s2pf	382	36	-	-	HYPH
cord-256444-grw5s2pf	382	37	associated	associate	VBN
cord-256444-grw5s2pf	382	38	domain	domain	NN
cord-256444-grw5s2pf	382	39	;	;	:
cord-256444-grw5s2pf	382	40	GFL	GFL	NNP
cord-256444-grw5s2pf	382	41	,	,	,
cord-256444-grw5s2pf	382	42	growth	growth	NN
cord-256444-grw5s2pf	382	43	factorlike	factorlike	NN
cord-256444-grw5s2pf	382	44	;	;	:
cord-256444-grw5s2pf	382	45	POL	POL	NNP
cord-256444-grw5s2pf	382	46	,	,	,
cord-256444-grw5s2pf	382	47	RNA	rna	NN
cord-256444-grw5s2pf	382	48	-	-	HYPH
cord-256444-grw5s2pf	382	49	dependent	dependent	JJ
cord-256444-grw5s2pf	382	50	RNA	RNA	NNP
cord-256444-grw5s2pf	382	51	polymerase	polymerase	NN
cord-256444-grw5s2pf	382	52	;	;	:
cord-256444-grw5s2pf	382	53	MB	mb	NN
cord-256444-grw5s2pf	382	54	,	,	,
cord-256444-grw5s2pf	382	55	metal	metal	NN
cord-256444-grw5s2pf	382	56	-	-	HYPH
cord-256444-grw5s2pf	382	57	binding	bind	VBG
cord-256444-grw5s2pf	382	58	motif	motif	NN
cord-256444-grw5s2pf	382	59	;	;	:
cord-256444-grw5s2pf	382	60	HEL	HEL	NNP
cord-256444-grw5s2pf	382	61	,	,	,
cord-256444-grw5s2pf	382	62	helicase	helicase	NN
cord-256444-grw5s2pf	382	63	.	.	.
cord-256444-grw5s2pf	383	1	(	(	-LRB-
cord-256444-grw5s2pf	383	2	c	c	LS
cord-256444-grw5s2pf	383	3	)	)	-RRB-
cord-256444-grw5s2pf	383	4	Genetic	genetic	JJ
cord-256444-grw5s2pf	383	5	complementation	complementation	NN
cord-256444-grw5s2pf	383	6	groups	group	NNS
cord-256444-grw5s2pf	383	7	Fu	Fu	NNP
cord-256444-grw5s2pf	383	8	and	and	CC
cord-256444-grw5s2pf	383	9	Baric	Baric	NNP
cord-256444-grw5s2pf	383	10	,	,	,
cord-256444-grw5s2pf	383	11	1994	1994	CD
cord-256444-grw5s2pf	383	12	)	)	-RRB-
cord-256444-grw5s2pf	383	13	.	.	.
cord-256444-grw5s2pf	384	1	(	(	-LRB-
cord-256444-grw5s2pf	384	2	d	d	LS
cord-256444-grw5s2pf	384	3	)	)	-RRB-
cord-256444-grw5s2pf	384	4	Processing	processing	NN
cord-256444-grw5s2pf	384	5	scheme	scheme	NN
cord-256444-grw5s2pf	384	6	for	for	IN
cord-256444-grw5s2pf	384	7	part	part	NN
cord-256444-grw5s2pf	384	8	of	of	IN
cord-256444-grw5s2pf	384	9	the	the	DT
cord-256444-grw5s2pf	384	10	l	l	NNP
cord-256444-grw5s2pf	384	11	a	a	DT
cord-256444-grw5s2pf	384	12	ORF	ORF	NNP
cord-256444-grw5s2pf	384	13	(	(	-LRB-
cord-256444-grw5s2pf	384	14	Denison	Denison	NNP
cord-256444-grw5s2pf	384	15	et	et	NNP
cord-256444-grw5s2pf	384	16	al	al	NNP
cord-256444-grw5s2pf	384	17	.	.	NNP
cord-256444-grw5s2pf	384	18	,	,	,
cord-256444-grw5s2pf	384	19	1992	1992	CD
cord-256444-grw5s2pf	384	20	(	(	-LRB-
cord-256444-grw5s2pf	384	21	3CLP	3CLP	NNP
cord-256444-grw5s2pf	384	22	)	)	-RRB-
cord-256444-grw5s2pf	384	23	and	and	CC
cord-256444-grw5s2pf	384	24	a	a	DT
cord-256444-grw5s2pf	384	25	cysteine	cysteine	NN
cord-256444-grw5s2pf	384	26	-	-	HYPH
cord-256444-grw5s2pf	384	27	rich	rich	JJ
cord-256444-grw5s2pf	384	28	growth	growth	NN
cord-256444-grw5s2pf	384	29	factor	factor	NN
cord-256444-grw5s2pf	384	30	-	-	HYPH
cord-256444-grw5s2pf	384	31	related	relate	VBN
cord-256444-grw5s2pf	384	32	protein	protein	NN
cord-256444-grw5s2pf	384	33	(	(	-LRB-
cord-256444-grw5s2pf	384	34	GFL	GFL	NNP
cord-256444-grw5s2pf	384	35	)	)	-RRB-
cord-256444-grw5s2pf	384	36	.	.	.
cord-256444-grw5s2pf	385	1	MHV	MHV	NNP
cord-256444-grw5s2pf	385	2	,	,	,
cord-256444-grw5s2pf	385	3	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	385	4	,	,	,
cord-256444-grw5s2pf	385	5	and	and	CC
cord-256444-grw5s2pf	385	6	TGEV	TGEV	NNP
cord-256444-grw5s2pf	385	7	have	have	VBP
cord-256444-grw5s2pf	385	8	two	two	CD
cord-256444-grw5s2pf	385	9	PLP	PLP	NNP
cord-256444-grw5s2pf	385	10	domains	domain	NNS
cord-256444-grw5s2pf	385	11	(	(	-LRB-
cord-256444-grw5s2pf	385	12	1	1	CD
cord-256444-grw5s2pf	385	13	and	and	CC
cord-256444-grw5s2pf	385	14	21	21	CD
cord-256444-grw5s2pf	385	15	,	,	,
cord-256444-grw5s2pf	385	16	with	with	IN
cord-256444-grw5s2pf	385	17	PLPB	PLPB	NNS
cord-256444-grw5s2pf	385	18	corresponding	correspond	VBG
cord-256444-grw5s2pf	385	19	to	to	IN
cord-256444-grw5s2pf	385	20	the	the	DT
cord-256444-grw5s2pf	385	21	single	single	JJ
cord-256444-grw5s2pf	385	22	PLP	PLP	NNP
cord-256444-grw5s2pf	385	23	domain	domain	NN
cord-256444-grw5s2pf	385	24	of	of	IN
cord-256444-grw5s2pf	385	25	IBV	IBV	NNP
cord-256444-grw5s2pf	385	26	.	.	.
cord-256444-grw5s2pf	386	1	Sequence	sequence	NN
cord-256444-grw5s2pf	386	2	corresponding	correspond	VBG
cord-256444-grw5s2pf	386	3	to	to	IN
cord-256444-grw5s2pf	386	4	a	a	DT
cord-256444-grw5s2pf	386	5	cysteine	cysteine	NN
cord-256444-grw5s2pf	386	6	protease	protease	NN
cord-256444-grw5s2pf	386	7	of	of	IN
cord-256444-grw5s2pf	386	8	Streptococcus	streptococcus	NN
cord-256444-grw5s2pf	386	9	pneumoniae	pneumoniae	NN
cord-256444-grw5s2pf	386	10	has	have	VBZ
cord-256444-grw5s2pf	386	11	been	be	VBN
cord-256444-grw5s2pf	386	12	identified	identify	VBN
cord-256444-grw5s2pf	386	13	in	in	IN
cord-256444-grw5s2pf	386	14	l	l	NNP
cord-256444-grw5s2pf	386	15	a	a	NN
cord-256444-grw5s2pf	386	16	of	of	IN
cord-256444-grw5s2pf	386	17	IBV	IBV	NNP
cord-256444-grw5s2pf	386	18	.	.	.
cord-256444-grw5s2pf	387	1	Upsteam	Upsteam	NNP
cord-256444-grw5s2pf	387	2	of	of	IN
cord-256444-grw5s2pf	387	3	PLPB	PLPB	NNP
cord-256444-grw5s2pf	387	4	is	be	VBZ
cord-256444-grw5s2pf	387	5	a	a	DT
cord-256444-grw5s2pf	387	6	region	region	NN
cord-256444-grw5s2pf	387	7	termed	term	VBN
cord-256444-grw5s2pf	387	8	the	the	DT
cord-256444-grw5s2pf	387	9	X	x	NN
cord-256444-grw5s2pf	387	10	domain	domain	NN
cord-256444-grw5s2pf	387	11	,	,	,
cord-256444-grw5s2pf	387	12	a	a	DT
cord-256444-grw5s2pf	387	13	region	region	NN
cord-256444-grw5s2pf	387	14	of	of	IN
cord-256444-grw5s2pf	387	15	particularly	particularly	RB
cord-256444-grw5s2pf	387	16	high	high	JJ
cord-256444-grw5s2pf	387	17	conservation	conservation	NN
cord-256444-grw5s2pf	387	18	between	between	IN
cord-256444-grw5s2pf	387	19	IBV	IBV	NNP
cord-256444-grw5s2pf	387	20	and	and	CC
cord-256444-grw5s2pf	387	21	MHV	MHV	NNP
cord-256444-grw5s2pf	387	22	and	and	CC
cord-256444-grw5s2pf	387	23	similar	similar	JJ
cord-256444-grw5s2pf	387	24	to	to	IN
cord-256444-grw5s2pf	387	25	one	one	CD
cord-256444-grw5s2pf	387	26	near	near	IN
cord-256444-grw5s2pf	387	27	the	the	DT
cord-256444-grw5s2pf	387	28	thiol	thiol	NN
cord-256444-grw5s2pf	387	29	protease	protease	NN
cord-256444-grw5s2pf	387	30	of	of	IN
cord-256444-grw5s2pf	387	31	alpha	alpha	NN
cord-256444-grw5s2pf	387	32	-	-	HYPH
cord-256444-grw5s2pf	387	33	and	and	CC
cord-256444-grw5s2pf	387	34	rubiviruses	rubiviruse	NNS
cord-256444-grw5s2pf	387	35	.	.	.
cord-256444-grw5s2pf	388	1	There	there	EX
cord-256444-grw5s2pf	388	2	is	be	VBZ
cord-256444-grw5s2pf	388	3	no	no	DT
cord-256444-grw5s2pf	388	4	functional	functional	JJ
cord-256444-grw5s2pf	388	5	evidence	evidence	NN
cord-256444-grw5s2pf	388	6	so	so	RB
cord-256444-grw5s2pf	388	7	far	far	RB
cord-256444-grw5s2pf	388	8	to	to	TO
cord-256444-grw5s2pf	388	9	link	link	VB
cord-256444-grw5s2pf	388	10	the	the	DT
cord-256444-grw5s2pf	388	11	GFL	GFL	NNP
cord-256444-grw5s2pf	388	12	with	with	IN
cord-256444-grw5s2pf	388	13	known	know	VBN
cord-256444-grw5s2pf	388	14	growth	growth	NN
cord-256444-grw5s2pf	388	15	factors	factor	NNS
cord-256444-grw5s2pf	388	16	,	,	,
cord-256444-grw5s2pf	388	17	but	but	CC
cord-256444-grw5s2pf	388	18	the	the	DT
cord-256444-grw5s2pf	388	19	predictions	prediction	NNS
cord-256444-grw5s2pf	388	20	of	of	IN
cord-256444-grw5s2pf	388	21	most	most	JJS
cord-256444-grw5s2pf	388	22	of	of	IN
cord-256444-grw5s2pf	388	23	the	the	DT
cord-256444-grw5s2pf	388	24	protease	protease	NN
cord-256444-grw5s2pf	388	25	domains	domain	NNS
cord-256444-grw5s2pf	388	26	have	have	VBP
cord-256444-grw5s2pf	388	27	been	be	VBN
cord-256444-grw5s2pf	388	28	confirmed	confirm	VBN
cord-256444-grw5s2pf	388	29	by	by	IN
cord-256444-grw5s2pf	388	30	experimental	experimental	JJ
cord-256444-grw5s2pf	388	31	analysis	analysis	NN
cord-256444-grw5s2pf	388	32	.	.	.
cord-256444-grw5s2pf	389	1	The	the	DT
cord-256444-grw5s2pf	389	2	first	first	JJ
cord-256444-grw5s2pf	389	3	PLP	PLP	NNP
cord-256444-grw5s2pf	389	4	domain	domain	NN
cord-256444-grw5s2pf	389	5	of	of	IN
cord-256444-grw5s2pf	389	6	MHV	MHV	NNP
cord-256444-grw5s2pf	389	7	is	be	VBZ
cord-256444-grw5s2pf	389	8	responsible	responsible	JJ
cord-256444-grw5s2pf	389	9	for	for	IN
cord-256444-grw5s2pf	389	10	the	the	DT
cord-256444-grw5s2pf	389	11	cleavage	cleavage	NN
cord-256444-grw5s2pf	389	12	of	of	IN
cord-256444-grw5s2pf	389	13	p28	p28	CD
cord-256444-grw5s2pf	389	14	/	/	SYM
cord-256444-grw5s2pf	389	15	p30	p30	NN
cord-256444-grw5s2pf	389	16	and	and	CC
cord-256444-grw5s2pf	389	17	p65	p65	NN
cord-256444-grw5s2pf	389	18	from	from	IN
cord-256444-grw5s2pf	389	19	the	the	DT
cord-256444-grw5s2pf	389	20	N	n	CD
cord-256444-grw5s2pf	389	21	terminus	terminus	NN
cord-256444-grw5s2pf	389	22	of	of	IN
cord-256444-grw5s2pf	389	23	the	the	DT
cord-256444-grw5s2pf	389	24	MHV	MHV	NNP
cord-256444-grw5s2pf	389	25	ORF	ORF	NNP
cord-256444-grw5s2pf	389	26	l	l	NNP
cord-256444-grw5s2pf	389	27	a	a	DT
cord-256444-grw5s2pf	389	28	polyprotein	polyprotein	NN
cord-256444-grw5s2pf	389	29	(	(	-LRB-
cord-256444-grw5s2pf	389	30	Fig	Fig	NNP
cord-256444-grw5s2pf	389	31	.	.	.
cord-256444-grw5s2pf	389	32	6	6	CD
cord-256444-grw5s2pf	389	33	)	)	-RRB-
cord-256444-grw5s2pf	390	1	(	(	-LRB-
cord-256444-grw5s2pf	390	2	Baker	Baker	NNP
cord-256444-grw5s2pf	390	3	et	et	NNP
cord-256444-grw5s2pf	390	4	al	al	NNP
cord-256444-grw5s2pf	390	5	.	.	.
cord-256444-grw5s2pf	391	1	,	,	,
cord-256444-grw5s2pf	391	2	1989	1989	CD
cord-256444-grw5s2pf	391	3	(	(	-LRB-
cord-256444-grw5s2pf	391	4	Baker	Baker	NNP
cord-256444-grw5s2pf	391	5	et	et	NNP
cord-256444-grw5s2pf	391	6	al	al	NNP
cord-256444-grw5s2pf	391	7	.	.	.
cord-256444-grw5s2pf	392	1	,	,	,
cord-256444-grw5s2pf	392	2	,	,	,
cord-256444-grw5s2pf	392	3	1993	1993	CD
cord-256444-grw5s2pf	392	4	Bonilla	Bonilla	NNP
cord-256444-grw5s2pf	392	5	et	et	NNP
cord-256444-grw5s2pf	392	6	al	al	NNP
cord-256444-grw5s2pf	392	7	.	.	.
cord-256444-grw5s2pf	393	1	,	,	,
cord-256444-grw5s2pf	393	2	1995	1995	CD
cord-256444-grw5s2pf	393	3	Bonilla	Bonilla	NNP
cord-256444-grw5s2pf	393	4	et	et	NNP
cord-256444-grw5s2pf	393	5	al	al	NNP
cord-256444-grw5s2pf	393	6	.	.	NNP
cord-256444-grw5s2pf	393	7	,	,	,
cord-256444-grw5s2pf	393	8	,	,	,
cord-256444-grw5s2pf	393	9	1997	1997	CD
cord-256444-grw5s2pf	393	10	.	.	.
cord-256444-grw5s2pf	394	1	This	this	DT
cord-256444-grw5s2pf	394	2	PLP	PLP	NNP
cord-256444-grw5s2pf	394	3	was	be	VBD
cord-256444-grw5s2pf	394	4	inhibited	inhibit	VBN
cord-256444-grw5s2pf	394	5	by	by	IN
cord-256444-grw5s2pf	394	6	zinc	zinc	NN
cord-256444-grw5s2pf	394	7	chloride	chloride	NN
cord-256444-grw5s2pf	394	8	but	but	CC
cord-256444-grw5s2pf	394	9	not	not	RB
cord-256444-grw5s2pf	394	10	by	by	IN
cord-256444-grw5s2pf	394	11	leupeptin	leupeptin	NNP
cord-256444-grw5s2pf	394	12	(	(	-LRB-
cord-256444-grw5s2pf	394	13	Baker	Baker	NNP
cord-256444-grw5s2pf	394	14	et	et	NNP
cord-256444-grw5s2pf	394	15	al	al	NNP
cord-256444-grw5s2pf	394	16	.	.	NNP
cord-256444-grw5s2pf	394	17	,	,	,
cord-256444-grw5s2pf	394	18	1989	1989	CD
cord-256444-grw5s2pf	394	19	;	;	:
cord-256444-grw5s2pf	394	20	Denison	Denison	NNP
cord-256444-grw5s2pf	394	21	et	et	NNP
cord-256444-grw5s2pf	394	22	al	al	NNP
cord-256444-grw5s2pf	394	23	.	.	NNP
cord-256444-grw5s2pf	394	24	,	,	,
cord-256444-grw5s2pf	394	25	1992	1992	CD
cord-256444-grw5s2pf	394	26	)	)	-RRB-
cord-256444-grw5s2pf	394	27	.	.	.
cord-256444-grw5s2pf	395	1	Deletion	deletion	NN
cord-256444-grw5s2pf	395	2	analysis	analysis	NN
cord-256444-grw5s2pf	395	3	defined	define	VBD
cord-256444-grw5s2pf	395	4	this	this	DT
cord-256444-grw5s2pf	395	5	proteinase	proteinase	NN
cord-256444-grw5s2pf	395	6	domain	domain	NN
cord-256444-grw5s2pf	395	7	to	to	TO
cord-256444-grw5s2pf	395	8	be	be	VB
cord-256444-grw5s2pf	395	9	within	within	IN
cord-256444-grw5s2pf	395	10	the	the	DT
cord-256444-grw5s2pf	395	11	sequence	sequence	NN
cord-256444-grw5s2pf	395	12	encoded	encode	VBN
cord-256444-grw5s2pf	395	13	by	by	IN
cord-256444-grw5s2pf	395	14	the	the	DT
cord-256444-grw5s2pf	395	15	3.6	3.6	CD
cord-256444-grw5s2pf	395	16	-	-	SYM
cord-256444-grw5s2pf	395	17	4.4-kb	4.4-kb	CD
cord-256444-grw5s2pf	395	18	region	region	NN
cord-256444-grw5s2pf	395	19	from	from	IN
cord-256444-grw5s2pf	395	20	the	the	DT
cord-256444-grw5s2pf	395	21	5	5	CD
cord-256444-grw5s2pf	395	22	'	'	NN
cord-256444-grw5s2pf	395	23	end	end	NN
cord-256444-grw5s2pf	395	24	of	of	IN
cord-256444-grw5s2pf	395	25	the	the	DT
cord-256444-grw5s2pf	395	26	genome	genome	NN
cord-256444-grw5s2pf	395	27	.	.	.
cord-256444-grw5s2pf	396	1	Site	site	NN
cord-256444-grw5s2pf	396	2	-	-	HYPH
cord-256444-grw5s2pf	396	3	directed	direct	VBN
cord-256444-grw5s2pf	396	4	mutagenesis	mutagenesis	NN
cord-256444-grw5s2pf	396	5	showed	show	VBD
cord-256444-grw5s2pf	396	6	that	that	IN
cord-256444-grw5s2pf	396	7	residues	residue	NNS
cord-256444-grw5s2pf	396	8	Cys-1137	Cys-1137	NNP
cord-256444-grw5s2pf	397	1	and	and	CC
cord-256444-grw5s2pf	397	2	His-1288	His-1288	NNP
cord-256444-grw5s2pf	397	3	were	be	VBD
cord-256444-grw5s2pf	397	4	essential	essential	JJ
cord-256444-grw5s2pf	397	5	for	for	IN
cord-256444-grw5s2pf	397	6	protease	protease	NN
cord-256444-grw5s2pf	397	7	activity	activity	NN
cord-256444-grw5s2pf	397	8	(	(	-LRB-
cord-256444-grw5s2pf	397	9	Baker	Baker	NNP
cord-256444-grw5s2pf	397	10	et	et	NNP
cord-256444-grw5s2pf	397	11	al	al	NNP
cord-256444-grw5s2pf	397	12	.	.	NNP
cord-256444-grw5s2pf	397	13	,	,	,
cord-256444-grw5s2pf	397	14	1993	1993	CD
cord-256444-grw5s2pf	397	15	)	)	-RRB-
cord-256444-grw5s2pf	397	16	.	.	.
cord-256444-grw5s2pf	398	1	Some	some	DT
cord-256444-grw5s2pf	398	2	amino	amino	NN
cord-256444-grw5s2pf	398	3	acid	acid	NN
cord-256444-grw5s2pf	398	4	sequences	sequence	NNS
cord-256444-grw5s2pf	398	5	between	between	IN
cord-256444-grw5s2pf	398	6	the	the	DT
cord-256444-grw5s2pf	398	7	p28	p28	CD
cord-256444-grw5s2pf	398	8	cleavage	cleavage	NN
cord-256444-grw5s2pf	398	9	site	site	NN
cord-256444-grw5s2pf	398	10	and	and	CC
cord-256444-grw5s2pf	398	11	the	the	DT
cord-256444-grw5s2pf	398	12	PLP	PLP	NNP
cord-256444-grw5s2pf	398	13	domain	domain	NN
cord-256444-grw5s2pf	398	14	were	be	VBD
cord-256444-grw5s2pf	398	15	also	also	RB
cord-256444-grw5s2pf	398	16	essential	essential	JJ
cord-256444-grw5s2pf	398	17	for	for	IN
cord-256444-grw5s2pf	398	18	the	the	DT
cord-256444-grw5s2pf	398	19	cis	cis	NNP
cord-256444-grw5s2pf	398	20	cleavage	cleavage	NN
cord-256444-grw5s2pf	398	21	that	that	WDT
cord-256444-grw5s2pf	398	22	generates	generate	VBZ
cord-256444-grw5s2pf	398	23	p28	p28	CD
cord-256444-grw5s2pf	398	24	(	(	-LRB-
cord-256444-grw5s2pf	398	25	Baker	Baker	NNP
cord-256444-grw5s2pf	398	26	et	et	NNP
cord-256444-grw5s2pf	398	27	al	al	NNP
cord-256444-grw5s2pf	398	28	.	.	NNP
cord-256444-grw5s2pf	398	29	,	,	,
cord-256444-grw5s2pf	398	30	1993	1993	CD
cord-256444-grw5s2pf	398	31	;	;	:
cord-256444-grw5s2pf	398	32	Bonilla	Bonilla	NNP
cord-256444-grw5s2pf	398	33	et	et	NNP
cord-256444-grw5s2pf	398	34	al	al	NNP
cord-256444-grw5s2pf	398	35	.	.	NNP
cord-256444-grw5s2pf	398	36	,	,	,
cord-256444-grw5s2pf	398	37	1995	1995	CD
cord-256444-grw5s2pf	398	38	)	)	-RRB-
cord-256444-grw5s2pf	398	39	.	.	.
cord-256444-grw5s2pf	399	1	The	the	DT
cord-256444-grw5s2pf	399	2	function	function	NN
cord-256444-grw5s2pf	399	3	of	of	IN
cord-256444-grw5s2pf	399	4	PLP2	PLP2	NNP
cord-256444-grw5s2pf	399	5	has	have	VBZ
cord-256444-grw5s2pf	399	6	not	not	RB
cord-256444-grw5s2pf	399	7	been	be	VBN
cord-256444-grw5s2pf	399	8	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	399	9	.	.	.
cord-256444-grw5s2pf	400	1	The	the	DT
cord-256444-grw5s2pf	400	2	3CLP	3clp	CD
cord-256444-grw5s2pf	400	3	domain	domain	NN
cord-256444-grw5s2pf	400	4	extends	extend	VBZ
cord-256444-grw5s2pf	400	5	for	for	IN
cord-256444-grw5s2pf	400	6	approximately	approximately	RB
cord-256444-grw5s2pf	400	7	300	300	CD
cord-256444-grw5s2pf	400	8	amino	amino	NN
cord-256444-grw5s2pf	400	9	acids	acid	NNS
cord-256444-grw5s2pf	400	10	and	and	CC
cord-256444-grw5s2pf	400	11	is	be	VBZ
cord-256444-grw5s2pf	400	12	homologous	homologous	JJ
cord-256444-grw5s2pf	400	13	to	to	IN
cord-256444-grw5s2pf	400	14	proteases	protease	NNS
cord-256444-grw5s2pf	400	15	encoded	encode	VBN
cord-256444-grw5s2pf	400	16	by	by	IN
cord-256444-grw5s2pf	400	17	picornaviruses	picornavirus	NNS
cord-256444-grw5s2pf	400	18	and	and	CC
cord-256444-grw5s2pf	400	19	several	several	JJ
cord-256444-grw5s2pf	400	20	other	other	JJ
cord-256444-grw5s2pf	400	21	virus	virus	NN
cord-256444-grw5s2pf	400	22	genera	genus	NNS
cord-256444-grw5s2pf	400	23	.	.	.
cord-256444-grw5s2pf	401	1	The	the	DT
cord-256444-grw5s2pf	401	2	putative	putative	JJ
cord-256444-grw5s2pf	401	3	3CLP	3clp	CD
cord-256444-grw5s2pf	401	4	domain	domain	NN
cord-256444-grw5s2pf	401	5	of	of	IN
cord-256444-grw5s2pf	401	6	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	401	7	has	have	VBZ
cord-256444-grw5s2pf	401	8	been	be	VBN
cord-256444-grw5s2pf	401	9	expressed	express	VBN
cord-256444-grw5s2pf	401	10	as	as	IN
cord-256444-grw5s2pf	401	11	a	a	DT
cord-256444-grw5s2pf	401	12	/?-galactosidase	/?-galactosidase	CD
cord-256444-grw5s2pf	401	13	fusion	fusion	NN
cord-256444-grw5s2pf	401	14	protein	protein	NN
cord-256444-grw5s2pf	401	15	in	in	IN
cord-256444-grw5s2pf	401	16	Escherichia	Escherichia	NNP
cord-256444-grw5s2pf	401	17	coli	coli	NNS
cord-256444-grw5s2pf	401	18	and	and	CC
cord-256444-grw5s2pf	401	19	shown	show	VBN
cord-256444-grw5s2pf	401	20	to	to	TO
cord-256444-grw5s2pf	401	21	have	have	VB
cord-256444-grw5s2pf	401	22	autocatalytic	autocatalytic	JJ
cord-256444-grw5s2pf	401	23	proteolytic	proteolytic	JJ
cord-256444-grw5s2pf	401	24	activity	activity	NN
cord-256444-grw5s2pf	401	25	,	,	,
cord-256444-grw5s2pf	401	26	releasing	release	VBG
cord-256444-grw5s2pf	401	27	an	an	DT
cord-256444-grw5s2pf	401	28	active	active	JJ
cord-256444-grw5s2pf	401	29	3CLP	3clp	DT
cord-256444-grw5s2pf	401	30	protein	protein	NN
cord-256444-grw5s2pf	401	31	(	(	-LRB-
cord-256444-grw5s2pf	401	32	Ziebuhr	Ziebuhr	NNP
cord-256444-grw5s2pf	401	33	et	et	NNP
cord-256444-grw5s2pf	401	34	al	al	NNP
cord-256444-grw5s2pf	401	35	.	.	NNP
cord-256444-grw5s2pf	401	36	,	,	,
cord-256444-grw5s2pf	401	37	1995	1995	CD
cord-256444-grw5s2pf	401	38	)	)	-RRB-
cord-256444-grw5s2pf	401	39	.	.	.
cord-256444-grw5s2pf	402	1	An	an	DT
cord-256444-grw5s2pf	402	2	antiserum	antiserum	NN
cord-256444-grw5s2pf	402	3	against	against	IN
cord-256444-grw5s2pf	402	4	this	this	DT
cord-256444-grw5s2pf	402	5	fusion	fusion	NN
cord-256444-grw5s2pf	402	6	protein	protein	NN
cord-256444-grw5s2pf	402	7	immunoprecipitated	immunoprecipitate	VBD
cord-256444-grw5s2pf	402	8	a	a	DT
cord-256444-grw5s2pf	402	9	34-kDa	34-kda	CD
cord-256444-grw5s2pf	402	10	protein	protein	NN
cord-256444-grw5s2pf	402	11	from	from	IN
cord-256444-grw5s2pf	402	12	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	402	13	-	-	HYPH
cord-256444-grw5s2pf	402	14	infected	infect	VBN
cord-256444-grw5s2pf	402	15	cells	cell	NNS
cord-256444-grw5s2pf	402	16	.	.	.
cord-256444-grw5s2pf	403	1	Similar	similar	JJ
cord-256444-grw5s2pf	403	2	activity	activity	NN
cord-256444-grw5s2pf	403	3	has	have	VBZ
cord-256444-grw5s2pf	403	4	been	be	VBN
cord-256444-grw5s2pf	403	5	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	403	6	for	for	IN
cord-256444-grw5s2pf	403	7	the	the	DT
cord-256444-grw5s2pf	403	8	3CLPs	3clps	NN
cord-256444-grw5s2pf	403	9	of	of	IN
cord-256444-grw5s2pf	403	10	MHV	MHV	NNP
cord-256444-grw5s2pf	403	11	and	and	CC
cord-256444-grw5s2pf	403	12	IBV	IBV	NNP
cord-256444-grw5s2pf	403	13	(	(	-LRB-
cord-256444-grw5s2pf	403	14	Tibbles	Tibbles	NNP
cord-256444-grw5s2pf	403	15	et	et	FW
cord-256444-grw5s2pf	403	16	al	al	NNP
cord-256444-grw5s2pf	403	17	.	.	NNP
cord-256444-grw5s2pf	403	18	,	,	,
cord-256444-grw5s2pf	403	19	1996	1996	CD
cord-256444-grw5s2pf	403	20	)	)	-RRB-
cord-256444-grw5s2pf	403	21	.	.	.
cord-256444-grw5s2pf	404	1	This	this	DT
cord-256444-grw5s2pf	404	2	protease	protease	NN
cord-256444-grw5s2pf	404	3	cleaves	cleave	VBZ
cord-256444-grw5s2pf	404	4	not	not	RB
cord-256444-grw5s2pf	404	5	only	only	RB
cord-256444-grw5s2pf	404	6	its	-PRON-	PRP$
cord-256444-grw5s2pf	404	7	own	own	JJ
cord-256444-grw5s2pf	404	8	boundaries	boundary	NNS
cord-256444-grw5s2pf	404	9	but	but	CC
cord-256444-grw5s2pf	404	10	also	also	RB
cord-256444-grw5s2pf	404	11	several	several	JJ
cord-256444-grw5s2pf	404	12	downstream	downstream	JJ
cord-256444-grw5s2pf	404	13	sites	site	NNS
cord-256444-grw5s2pf	404	14	within	within	IN
cord-256444-grw5s2pf	404	15	ORF	ORF	NNP
cord-256444-grw5s2pf	404	16	l	l	NNP
cord-256444-grw5s2pf	404	17	a	a	NNP
cord-256444-grw5s2pf	404	18	and	and	CC
cord-256444-grw5s2pf	404	19	ORF	ORF	NNP
cord-256444-grw5s2pf	404	20	lb	lb	NNS
cord-256444-grw5s2pf	404	21	,	,	,
cord-256444-grw5s2pf	404	22	probably	probably	RB
cord-256444-grw5s2pf	404	23	both	both	DT
cord-256444-grw5s2pf	404	24	in	in	IN
cord-256444-grw5s2pf	404	25	cis	cis	NNP
cord-256444-grw5s2pf	404	26	and	and	CC
cord-256444-grw5s2pf	404	27	in	in	IN
cord-256444-grw5s2pf	404	28	trans	trans	NNP
cord-256444-grw5s2pf	404	29	.	.	.
cord-256444-grw5s2pf	405	1	Computer	computer	NN
cord-256444-grw5s2pf	405	2	analysis	analysis	NN
cord-256444-grw5s2pf	405	3	predicted	predict	VBD
cord-256444-grw5s2pf	405	4	that	that	IN
cord-256444-grw5s2pf	405	5	the	the	DT
cord-256444-grw5s2pf	405	6	catalytic	catalytic	JJ
cord-256444-grw5s2pf	405	7	center	center	NN
cord-256444-grw5s2pf	405	8	of	of	IN
cord-256444-grw5s2pf	405	9	the	the	DT
cord-256444-grw5s2pf	405	10	IBV	IBV	NNP
cord-256444-grw5s2pf	405	11	3CLP	3clp	XX
cord-256444-grw5s2pf	405	12	would	would	MD
cord-256444-grw5s2pf	405	13	include	include	VB
cord-256444-grw5s2pf	405	14	Cys-2922	Cys-2922	NNP
cord-256444-grw5s2pf	405	15	,	,	,
cord-256444-grw5s2pf	405	16	His-2820	His-2820	NNP
cord-256444-grw5s2pf	405	17	,	,	,
cord-256444-grw5s2pf	405	18	and	and	CC
cord-256444-grw5s2pf	405	19	Glu-2843	Glu-2843	NNP
cord-256444-grw5s2pf	405	20	(	(	-LRB-
cord-256444-grw5s2pf	406	1	Gorbalenya	Gorbalenya	NNP
cord-256444-grw5s2pf	406	2	et	et	NNP
cord-256444-grw5s2pf	406	3	al	al	NNP
cord-256444-grw5s2pf	406	4	.	.	NNP
cord-256444-grw5s2pf	406	5	,	,	,
cord-256444-grw5s2pf	406	6	1989a	1989a	CD
cord-256444-grw5s2pf	406	7	,	,	,
cord-256444-grw5s2pf	406	8	b	b	LS
cord-256444-grw5s2pf	406	9	)	)	-RRB-
cord-256444-grw5s2pf	406	10	.	.	.
cord-256444-grw5s2pf	407	1	Site	site	NN
cord-256444-grw5s2pf	407	2	-	-	HYPH
cord-256444-grw5s2pf	407	3	directed	direct	VBN
cord-256444-grw5s2pf	407	4	mutagenesis	mutagenesis	NN
cord-256444-grw5s2pf	407	5	confirmed	confirm	VBD
cord-256444-grw5s2pf	407	6	the	the	DT
cord-256444-grw5s2pf	407	7	role	role	NN
cord-256444-grw5s2pf	407	8	of	of	IN
cord-256444-grw5s2pf	407	9	the	the	DT
cord-256444-grw5s2pf	407	10	Cys	Cys	NNP
cord-256444-grw5s2pf	407	11	and	and	CC
cord-256444-grw5s2pf	407	12	His	-PRON-	PRP$
cord-256444-grw5s2pf	407	13	residues	residue	NNS
cord-256444-grw5s2pf	407	14	but	but	CC
cord-256444-grw5s2pf	407	15	showed	show	VBD
cord-256444-grw5s2pf	407	16	that	that	IN
cord-256444-grw5s2pf	407	17	the	the	DT
cord-256444-grw5s2pf	407	18	Glu	Glu	NNP
cord-256444-grw5s2pf	407	19	residue	residue	NN
cord-256444-grw5s2pf	407	20	was	be	VBD
cord-256444-grw5s2pf	407	21	not	not	RB
cord-256444-grw5s2pf	407	22	essential	essential	JJ
cord-256444-grw5s2pf	407	23	(	(	-LRB-
cord-256444-grw5s2pf	407	24	Liu	Liu	NNP
cord-256444-grw5s2pf	407	25	and	and	CC
cord-256444-grw5s2pf	407	26	Brown	Brown	NNP
cord-256444-grw5s2pf	407	27	,	,	,
cord-256444-grw5s2pf	407	28	1995	1995	CD
cord-256444-grw5s2pf	407	29	)	)	-RRB-
cord-256444-grw5s2pf	407	30	.	.	.
cord-256444-grw5s2pf	408	1	The	the	DT
cord-256444-grw5s2pf	408	2	same	same	JJ
cord-256444-grw5s2pf	408	3	approach	approach	NN
cord-256444-grw5s2pf	408	4	confirmed	confirm	VBD
cord-256444-grw5s2pf	408	5	that	that	IN
cord-256444-grw5s2pf	408	6	the	the	DT
cord-256444-grw5s2pf	408	7	predicted	predicted	JJ
cord-256444-grw5s2pf	408	8	QS(G	QS(G	NNP
cord-256444-grw5s2pf	408	9	)	)	-RRB-
cord-256444-grw5s2pf	408	10	dipeptide	dipeptide	NN
cord-256444-grw5s2pf	408	11	bonds	bond	NNS
cord-256444-grw5s2pf	408	12	in	in	IN
cord-256444-grw5s2pf	408	13	the	the	DT
cord-256444-grw5s2pf	408	14	l	l	NNP
cord-256444-grw5s2pf	408	15	b	b	NNP
cord-256444-grw5s2pf	408	16	ORF	ORF	NNP
cord-256444-grw5s2pf	408	17	are	be	VBP
cord-256444-grw5s2pf	408	18	the	the	DT
cord-256444-grw5s2pf	408	19	targets	target	NNS
cord-256444-grw5s2pf	408	20	for	for	IN
cord-256444-grw5s2pf	408	21	the	the	DT
cord-256444-grw5s2pf	408	22	protease	protease	NN
cord-256444-grw5s2pf	408	23	activity	activity	NN
cord-256444-grw5s2pf	408	24	of	of	IN
cord-256444-grw5s2pf	408	25	the	the	DT
cord-256444-grw5s2pf	408	26	3CLP	3clp	CD
cord-256444-grw5s2pf	408	27	of	of	IN
cord-256444-grw5s2pf	408	28	IBV	IBV	NNP
cord-256444-grw5s2pf	408	29	(	(	-LRB-
cord-256444-grw5s2pf	408	30	discussed	discuss	VBN
cord-256444-grw5s2pf	408	31	further	further	RB
cord-256444-grw5s2pf	408	32	in	in	IN
cord-256444-grw5s2pf	408	33	Section	section	NN
cord-256444-grw5s2pf	408	34	V	v	NN
cord-256444-grw5s2pf	408	35	,	,	,
cord-256444-grw5s2pf	408	36	G	G	NNP
cord-256444-grw5s2pf	408	37	)	)	-RRB-
cord-256444-grw5s2pf	408	38	.	.	.
cord-256444-grw5s2pf	409	1	Similar	similar	JJ
cord-256444-grw5s2pf	409	2	conclusions	conclusion	NNS
cord-256444-grw5s2pf	409	3	were	be	VBD
cord-256444-grw5s2pf	409	4	reached	reach	VBN
cord-256444-grw5s2pf	409	5	for	for	IN
cord-256444-grw5s2pf	409	6	3CLP	3clp	DT
cord-256444-grw5s2pf	409	7	activity	activity	NN
cord-256444-grw5s2pf	409	8	of	of	IN
cord-256444-grw5s2pf	409	9	MHV	MHV	NNP
cord-256444-grw5s2pf	409	10	and	and	CC
cord-256444-grw5s2pf	409	11	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	409	12	Grotzinger	Grotzinger	NNP
cord-256444-grw5s2pf	409	13	et	et	NNP
cord-256444-grw5s2pf	409	14	al	al	NNP
cord-256444-grw5s2pf	409	15	.	.	NNP
cord-256444-grw5s2pf	409	16	,	,	,
cord-256444-grw5s2pf	409	17	1996	1996	CD
cord-256444-grw5s2pf	409	18	)	)	-RRB-
cord-256444-grw5s2pf	409	19	.	.	.
cord-256444-grw5s2pf	410	1	The	the	DT
cord-256444-grw5s2pf	410	2	importance	importance	NN
cord-256444-grw5s2pf	410	3	of	of	IN
cord-256444-grw5s2pf	410	4	Cys-3495	Cys-3495	NNP
cord-256444-grw5s2pf	410	5	in	in	IN
cord-256444-grw5s2pf	410	6	the	the	DT
cord-256444-grw5s2pf	410	7	3CLP	3clp	NN
cord-256444-grw5s2pf	410	8	of	of	IN
cord-256444-grw5s2pf	410	9	MHV	MHV	NNP
cord-256444-grw5s2pf	410	10	has	have	VBZ
cord-256444-grw5s2pf	410	11	been	be	VBN
cord-256444-grw5s2pf	410	12	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	410	13	(	(	-LRB-
cord-256444-grw5s2pf	410	14	Seybert	Seybert	NNP
cord-256444-grw5s2pf	410	15	et	et	FW
cord-256444-grw5s2pf	410	16	al	al	NNP
cord-256444-grw5s2pf	410	17	.	.	NNP
cord-256444-grw5s2pf	410	18	,	,	,
cord-256444-grw5s2pf	410	19	1997	1997	CD
cord-256444-grw5s2pf	410	20	)	)	-RRB-
cord-256444-grw5s2pf	410	21	.	.	.
cord-256444-grw5s2pf	411	1	In	in	IN
cord-256444-grw5s2pf	411	2	uitro	uitro	NNP
cord-256444-grw5s2pf	411	3	transcription	transcription	NN
cord-256444-grw5s2pf	411	4	and	and	CC
cord-256444-grw5s2pf	411	5	translation	translation	NN
cord-256444-grw5s2pf	411	6	of	of	IN
cord-256444-grw5s2pf	411	7	a	a	DT
cord-256444-grw5s2pf	411	8	cDNA	cdna	NN
cord-256444-grw5s2pf	411	9	containing	contain	VBG
cord-256444-grw5s2pf	411	10	the	the	DT
cord-256444-grw5s2pf	411	11	putative	putative	JJ
cord-256444-grw5s2pf	411	12	3CLP	3clp	CD
cord-256444-grw5s2pf	411	13	of	of	IN
cord-256444-grw5s2pf	411	14	MHV	MHV	NNP
cord-256444-grw5s2pf	411	15	produced	produce	VBD
cord-256444-grw5s2pf	411	16	polypeptides	polypeptide	NNS
cord-256444-grw5s2pf	411	17	of	of	IN
cord-256444-grw5s2pf	411	18	38	38	CD
cord-256444-grw5s2pf	411	19	and	and	CC
cord-256444-grw5s2pf	411	20	33	33	CD
cord-256444-grw5s2pf	411	21	kDa	kDa	NNS
cord-256444-grw5s2pf	411	22	,	,	,
cord-256444-grw5s2pf	411	23	which	which	WDT
cord-256444-grw5s2pf	411	24	were	be	VBD
cord-256444-grw5s2pf	411	25	subsequently	subsequently	RB
cord-256444-grw5s2pf	411	26	processed	process	VBN
cord-256444-grw5s2pf	411	27	to	to	IN
cord-256444-grw5s2pf	411	28	products	product	NNS
cord-256444-grw5s2pf	411	29	of	of	IN
cord-256444-grw5s2pf	411	30	32	32	CD
cord-256444-grw5s2pf	411	31	and	and	CC
cord-256444-grw5s2pf	411	32	27	27	CD
cord-256444-grw5s2pf	411	33	kDa	kDa	NNS
cord-256444-grw5s2pf	411	34	.	.	.
cord-256444-grw5s2pf	412	1	The	the	DT
cord-256444-grw5s2pf	412	2	27-kDa	27-kda	CD
cord-256444-grw5s2pf	412	3	protein	protein	NN
cord-256444-grw5s2pf	412	4	possesses	possess	VBZ
cord-256444-grw5s2pf	412	5	the	the	DT
cord-256444-grw5s2pf	412	6	3C	3c	NN
cord-256444-grw5s2pf	412	7	-	-	HYPH
cord-256444-grw5s2pf	412	8	like	like	JJ
cord-256444-grw5s2pf	412	9	protease	protease	NN
cord-256444-grw5s2pf	412	10	activity	activity	NN
cord-256444-grw5s2pf	412	11	(	(	-LRB-
cord-256444-grw5s2pf	412	12	Lu	Lu	NNP
cord-256444-grw5s2pf	412	13	et	et	FW
cord-256444-grw5s2pf	412	14	al	al	NNP
cord-256444-grw5s2pf	412	15	.	.	NNP
cord-256444-grw5s2pf	412	16	,	,	,
cord-256444-grw5s2pf	412	17	1996	1996	CD
cord-256444-grw5s2pf	412	18	)	)	-RRB-
cord-256444-grw5s2pf	412	19	.	.	.
cord-256444-grw5s2pf	413	1	The	the	DT
cord-256444-grw5s2pf	413	2	3CLP	3clp	CD
cord-256444-grw5s2pf	413	3	domain	domain	NN
cord-256444-grw5s2pf	413	4	is	be	VBZ
cord-256444-grw5s2pf	413	5	flanked	flank	VBN
cord-256444-grw5s2pf	413	6	by	by	IN
cord-256444-grw5s2pf	413	7	predicted	predict	VBN
cord-256444-grw5s2pf	413	8	membrane	membrane	NN
cord-256444-grw5s2pf	413	9	-	-	HYPH
cord-256444-grw5s2pf	413	10	spanning	span	VBG
cord-256444-grw5s2pf	413	11	domains	domain	NNS
cord-256444-grw5s2pf	413	12	,	,	,
cord-256444-grw5s2pf	413	13	which	which	WDT
cord-256444-grw5s2pf	413	14	may	may	MD
cord-256444-grw5s2pf	413	15	be	be	VB
cord-256444-grw5s2pf	413	16	important	important	JJ
cord-256444-grw5s2pf	413	17	for	for	IN
cord-256444-grw5s2pf	413	18	the	the	DT
cord-256444-grw5s2pf	413	19	proteolytic	proteolytic	JJ
cord-256444-grw5s2pf	413	20	activity	activity	NN
cord-256444-grw5s2pf	413	21	(	(	-LRB-
cord-256444-grw5s2pf	413	22	Tibbles	Tibbles	NNP
cord-256444-grw5s2pf	413	23	et	et	FW
cord-256444-grw5s2pf	413	24	al	al	NNP
cord-256444-grw5s2pf	413	25	.	.	NNP
cord-256444-grw5s2pf	413	26	,	,	,
cord-256444-grw5s2pf	413	27	1996	1996	CD
cord-256444-grw5s2pf	413	28	)	)	-RRB-
cord-256444-grw5s2pf	414	1	(	(	-LRB-
cord-256444-grw5s2pf	414	2	Fig	Fig	NNP
cord-256444-grw5s2pf	414	3	.	.	.
cord-256444-grw5s2pf	414	4	6	6	CD
cord-256444-grw5s2pf	414	5	)	)	-RRB-
cord-256444-grw5s2pf	414	6	.	.	.
cord-256444-grw5s2pf	415	1	Poor	poor	JJ
cord-256444-grw5s2pf	415	2	expression	expression	NN
cord-256444-grw5s2pf	415	3	of	of	IN
cord-256444-grw5s2pf	415	4	the	the	DT
cord-256444-grw5s2pf	415	5	IBV	IBV	NNP
cord-256444-grw5s2pf	415	6	3CLP	3clp	CD
cord-256444-grw5s2pf	415	7	protein	protein	NN
cord-256444-grw5s2pf	415	8	in	in	IN
cord-256444-grw5s2pf	415	9	vitro	vitro	FW
cord-256444-grw5s2pf	415	10	led	lead	VBD
cord-256444-grw5s2pf	415	11	to	to	IN
cord-256444-grw5s2pf	415	12	the	the	DT
cord-256444-grw5s2pf	415	13	discovery	discovery	NN
cord-256444-grw5s2pf	415	14	that	that	IN
cord-256444-grw5s2pf	415	15	this	this	DT
cord-256444-grw5s2pf	415	16	protease	protease	NN
cord-256444-grw5s2pf	415	17	was	be	VBD
cord-256444-grw5s2pf	415	18	ubiquinated	ubiquinate	VBN
cord-256444-grw5s2pf	415	19	and	and	CC
cord-256444-grw5s2pf	415	20	subsequently	subsequently	RB
cord-256444-grw5s2pf	415	21	degraded	degrade	VBN
cord-256444-grw5s2pf	415	22	by	by	IN
cord-256444-grw5s2pf	415	23	an	an	DT
cord-256444-grw5s2pf	415	24	adenosine	adenosine	NN
cord-256444-grw5s2pf	415	25	triphosphate	triphosphate	NN
cord-256444-grw5s2pf	415	26	(	(	-LRB-
cord-256444-grw5s2pf	415	27	ATP)-dependent	atp)-dependent	JJ
cord-256444-grw5s2pf	415	28	protease	protease	NN
cord-256444-grw5s2pf	415	29	present	present	JJ
cord-256444-grw5s2pf	415	30	in	in	IN
cord-256444-grw5s2pf	415	31	reticulocyte	reticulocyte	NN
cord-256444-grw5s2pf	415	32	lysate	lysate	NN
cord-256444-grw5s2pf	416	1	(	(	-LRB-
cord-256444-grw5s2pf	416	2	Tibbles	Tibbles	NNP
cord-256444-grw5s2pf	416	3	et	et	FW
cord-256444-grw5s2pf	416	4	al	al	NNP
cord-256444-grw5s2pf	416	5	.	.	NNP
cord-256444-grw5s2pf	416	6	,	,	,
cord-256444-grw5s2pf	416	7	1995	1995	CD
cord-256444-grw5s2pf	416	8	)	)	-RRB-
cord-256444-grw5s2pf	416	9	.	.	.
cord-256444-grw5s2pf	417	1	This	this	DT
cord-256444-grw5s2pf	417	2	is	be	VBZ
cord-256444-grw5s2pf	417	3	the	the	DT
cord-256444-grw5s2pf	417	4	third	third	JJ
cord-256444-grw5s2pf	417	5	example	example	NN
cord-256444-grw5s2pf	417	6	of	of	IN
cord-256444-grw5s2pf	417	7	a	a	DT
cord-256444-grw5s2pf	417	8	viral	viral	JJ
cord-256444-grw5s2pf	417	9	protein	protein	NN
cord-256444-grw5s2pf	417	10	subject	subject	NN
cord-256444-grw5s2pf	417	11	to	to	IN
cord-256444-grw5s2pf	417	12	turnover	turnover	NN
cord-256444-grw5s2pf	417	13	in	in	IN
cord-256444-grw5s2pf	417	14	this	this	DT
cord-256444-grw5s2pf	417	15	manner	manner	NN
cord-256444-grw5s2pf	417	16	and	and	CC
cord-256444-grw5s2pf	417	17	involves	involve	VBZ
cord-256444-grw5s2pf	417	18	a	a	DT
cord-256444-grw5s2pf	417	19	different	different	JJ
cord-256444-grw5s2pf	417	20	virus	virus	NN
cord-256444-grw5s2pf	417	21	class	class	NN
cord-256444-grw5s2pf	417	22	from	from	IN
cord-256444-grw5s2pf	417	23	the	the	DT
cord-256444-grw5s2pf	417	24	previously	previously	RB
cord-256444-grw5s2pf	417	25	reported	report	VBN
cord-256444-grw5s2pf	417	26	examples	example	NNS
cord-256444-grw5s2pf	417	27	,	,	,
cord-256444-grw5s2pf	417	28	in	in	IN
cord-256444-grw5s2pf	417	29	a	a	DT
cord-256444-grw5s2pf	417	30	picornavirus	picornavirus	NN
cord-256444-grw5s2pf	417	31	(	(	-LRB-
cord-256444-grw5s2pf	417	32	Oberst	Oberst	NNP
cord-256444-grw5s2pf	417	33	et	et	NNP
cord-256444-grw5s2pf	417	34	al	al	NNP
cord-256444-grw5s2pf	417	35	.	.	NNP
cord-256444-grw5s2pf	417	36	,	,	,
cord-256444-grw5s2pf	417	37	1993	1993	CD
cord-256444-grw5s2pf	417	38	)	)	-RRB-
cord-256444-grw5s2pf	417	39	and	and	CC
cord-256444-grw5s2pf	417	40	an	an	DT
cord-256444-grw5s2pf	417	41	alphavirus	alphavirus	NN
cord-256444-grw5s2pf	417	42	.	.	.
cord-256444-grw5s2pf	418	1	The	the	DT
cord-256444-grw5s2pf	418	2	ubiquitin	ubiquitin	NN
cord-256444-grw5s2pf	418	3	-	-	HYPH
cord-256444-grw5s2pf	418	4	mediated	mediate	VBN
cord-256444-grw5s2pf	418	5	,	,	,
cord-256444-grw5s2pf	418	6	ATP	ATP	NNP
cord-256444-grw5s2pf	418	7	-	-	HYPH
cord-256444-grw5s2pf	418	8	dependent	dependent	JJ
cord-256444-grw5s2pf	418	9	proteolytic	proteolytic	JJ
cord-256444-grw5s2pf	418	10	pathway	pathway	NN
cord-256444-grw5s2pf	418	11	is	be	VBZ
cord-256444-grw5s2pf	418	12	a	a	DT
cord-256444-grw5s2pf	418	13	major	major	JJ
cord-256444-grw5s2pf	418	14	cellular	cellular	NN
cord-256444-grw5s2pf	418	15	,	,	,
cord-256444-grw5s2pf	418	16	nonlysosomal	nonlysosomal	JJ
cord-256444-grw5s2pf	418	17	,	,	,
cord-256444-grw5s2pf	418	18	protein	protein	NN
cord-256444-grw5s2pf	418	19	degradation	degradation	NN
cord-256444-grw5s2pf	418	20	system	system	NN
cord-256444-grw5s2pf	418	21	,	,	,
cord-256444-grw5s2pf	418	22	which	which	WDT
cord-256444-grw5s2pf	418	23	may	may	MD
cord-256444-grw5s2pf	418	24	cause	cause	VB
cord-256444-grw5s2pf	418	25	rapid	rapid	JJ
cord-256444-grw5s2pf	418	26	turnover	turnover	NN
cord-256444-grw5s2pf	418	27	of	of	IN
cord-256444-grw5s2pf	418	28	the	the	DT
cord-256444-grw5s2pf	418	29	coronaviral	coronaviral	JJ
cord-256444-grw5s2pf	418	30	polymerase	polymerase	NN
cord-256444-grw5s2pf	418	31	.	.	.
cord-256444-grw5s2pf	419	1	The	the	DT
cord-256444-grw5s2pf	419	2	functional	functional	JJ
cord-256444-grw5s2pf	419	3	domains	domain	NNS
cord-256444-grw5s2pf	419	4	associated	associate	VBN
cord-256444-grw5s2pf	419	5	with	with	IN
cord-256444-grw5s2pf	419	6	RNA	RNA	NNP
cord-256444-grw5s2pf	419	7	synthesis	synthesis	NN
cord-256444-grw5s2pf	419	8	are	be	VBP
cord-256444-grw5s2pf	419	9	located	locate	VBN
cord-256444-grw5s2pf	419	10	within	within	IN
cord-256444-grw5s2pf	419	11	the	the	DT
cord-256444-grw5s2pf	419	12	more	more	RBR
cord-256444-grw5s2pf	419	13	conserved	conserved	JJ
cord-256444-grw5s2pf	419	14	l	l	NN
cord-256444-grw5s2pf	419	15	b	b	NNP
cord-256444-grw5s2pf	419	16	ORF	ORF	NNP
cord-256444-grw5s2pf	419	17	.	.	.
cord-256444-grw5s2pf	420	1	These	these	DT
cord-256444-grw5s2pf	420	2	include	include	VBP
cord-256444-grw5s2pf	420	3	domains	domain	NNS
cord-256444-grw5s2pf	420	4	for	for	IN
cord-256444-grw5s2pf	420	5	an	an	DT
cord-256444-grw5s2pf	420	6	RNAdependent	RNAdependent	NNP
cord-256444-grw5s2pf	420	7	RNA	RNA	NNP
cord-256444-grw5s2pf	420	8	polymerase	polymerase	NN
cord-256444-grw5s2pf	420	9	,	,	,
cord-256444-grw5s2pf	420	10	a	a	DT
cord-256444-grw5s2pf	420	11	nucleoside	nucleoside	NN
cord-256444-grw5s2pf	420	12	triphosphate	triphosphate	NN
cord-256444-grw5s2pf	420	13	(	(	-LRB-
cord-256444-grw5s2pf	420	14	NTP)-binding/	NTP)-binding/	NNP
cord-256444-grw5s2pf	420	15	helicase	helicase	NN
cord-256444-grw5s2pf	420	16	domain	domain	NN
cord-256444-grw5s2pf	420	17	,	,	,
cord-256444-grw5s2pf	420	18	and	and	CC
cord-256444-grw5s2pf	420	19	a	a	DT
cord-256444-grw5s2pf	420	20	zinc	zinc	NN
cord-256444-grw5s2pf	420	21	-	-	HYPH
cord-256444-grw5s2pf	420	22	finger	finger	NN
cord-256444-grw5s2pf	420	23	nucleic	nucleic	JJ
cord-256444-grw5s2pf	420	24	acid	acid	NN
cord-256444-grw5s2pf	420	25	-	-	HYPH
cord-256444-grw5s2pf	420	26	binding	bind	VBG
cord-256444-grw5s2pf	420	27	domain	domain	NN
cord-256444-grw5s2pf	420	28	(	(	-LRB-
cord-256444-grw5s2pf	420	29	metal	metal	NN
cord-256444-grw5s2pf	420	30	binding	bind	VBG
cord-256444-grw5s2pf	420	31	domain	domain	NN
cord-256444-grw5s2pf	420	32	)	)	-RRB-
cord-256444-grw5s2pf	420	33	(	(	-LRB-
cord-256444-grw5s2pf	420	34	Fig	Fig	NNP
cord-256444-grw5s2pf	420	35	.	.	.
cord-256444-grw5s2pf	420	36	6	6	CD
cord-256444-grw5s2pf	420	37	)	)	-RRB-
cord-256444-grw5s2pf	420	38	.	.	.
cord-256444-grw5s2pf	421	1	Computer	computer	NN
cord-256444-grw5s2pf	421	2	analyses	analysis	NNS
cord-256444-grw5s2pf	421	3	identified	identify	VBD
cord-256444-grw5s2pf	421	4	the	the	DT
cord-256444-grw5s2pf	421	5	polymerase	polymerase	NN
cord-256444-grw5s2pf	421	6	domain	domain	NN
cord-256444-grw5s2pf	421	7	 	 	_SP
cord-256444-grw5s2pf	422	1	H	h	NN
cord-256444-grw5s2pf	422	2	o	o	NN
cord-256444-grw5s2pf	422	3	d	d	NN
cord-256444-grw5s2pf	422	4	p	p	NN
cord-256444-grw5s2pf	422	5	a	a	NNP
cord-256444-grw5s2pf	422	6	n	n	NN
cord-256444-grw5s2pf	422	7	,	,	,
cord-256444-grw5s2pf	422	8	1988	1988	CD
cord-256444-grw5s2pf	422	9	;	;	:
cord-256444-grw5s2pf	423	1	Gorbalenya	Gorbalenya	NNP
cord-256444-grw5s2pf	423	2	et	et	NNP
cord-256444-grw5s2pf	423	3	al	al	NNP
cord-256444-grw5s2pf	423	4	.	.	NNP
cord-256444-grw5s2pf	423	5	,	,	,
cord-256444-grw5s2pf	423	6	1989a	1989a	CD
cord-256444-grw5s2pf	423	7	,	,	,
cord-256444-grw5s2pf	423	8	b	b	LS
cord-256444-grw5s2pf	423	9	)	)	-RRB-
cord-256444-grw5s2pf	423	10	.	.	.
cord-256444-grw5s2pf	424	1	Unlike	unlike	IN
cord-256444-grw5s2pf	424	2	the	the	DT
cord-256444-grw5s2pf	424	3	GDD	GDD	NNP
cord-256444-grw5s2pf	424	4	motif	motif	NN
cord-256444-grw5s2pf	424	5	present	present	JJ
cord-256444-grw5s2pf	424	6	in	in	IN
cord-256444-grw5s2pf	424	7	many	many	JJ
cord-256444-grw5s2pf	424	8	viruses	virus	NNS
cord-256444-grw5s2pf	424	9	,	,	,
cord-256444-grw5s2pf	424	10	the	the	DT
cord-256444-grw5s2pf	424	11	corresponding	corresponding	JJ
cord-256444-grw5s2pf	424	12	sequence	sequence	NN
cord-256444-grw5s2pf	424	13	in	in	IN
cord-256444-grw5s2pf	424	14	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	424	15	is	be	VBZ
cord-256444-grw5s2pf	424	16	SDD	SDD	NNP
cord-256444-grw5s2pf	424	17	.	.	.
cord-256444-grw5s2pf	425	1	Whether	whether	IN
cord-256444-grw5s2pf	425	2	the	the	DT
cord-256444-grw5s2pf	425	3	polymerase	polymerase	NN
cord-256444-grw5s2pf	425	4	gene	gene	NN
cord-256444-grw5s2pf	425	5	products	product	NNS
cord-256444-grw5s2pf	425	6	contain	contain	VBP
cord-256444-grw5s2pf	425	7	activities	activity	NNS
cord-256444-grw5s2pf	425	8	other	other	JJ
cord-256444-grw5s2pf	425	9	than	than	IN
cord-256444-grw5s2pf	425	10	proteases	protease	NNS
cord-256444-grw5s2pf	425	11	and	and	CC
cord-256444-grw5s2pf	425	12	polymerases	polymerase	NNS
cord-256444-grw5s2pf	425	13	is	be	VBZ
cord-256444-grw5s2pf	425	14	not	not	RB
cord-256444-grw5s2pf	425	15	known	know	VBN
cord-256444-grw5s2pf	425	16	.	.	.
cord-256444-grw5s2pf	426	1	The	the	DT
cord-256444-grw5s2pf	426	2	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	426	3	exhibit	exhibit	VBP
cord-256444-grw5s2pf	426	4	great	great	JJ
cord-256444-grw5s2pf	426	5	heterogeneity	heterogeneity	NN
cord-256444-grw5s2pf	426	6	with	with	IN
cord-256444-grw5s2pf	426	7	respect	respect	NN
cord-256444-grw5s2pf	426	8	to	to	IN
cord-256444-grw5s2pf	426	9	the	the	DT
cord-256444-grw5s2pf	426	10	number	number	NN
cord-256444-grw5s2pf	426	11	and	and	CC
cord-256444-grw5s2pf	426	12	genome	genome	NN
cord-256444-grw5s2pf	426	13	location	location	NN
cord-256444-grw5s2pf	426	14	of	of	IN
cord-256444-grw5s2pf	426	15	ns	ns	NNP
cord-256444-grw5s2pf	426	16	protein	protein	NN
cord-256444-grw5s2pf	426	17	genes	gene	NNS
cord-256444-grw5s2pf	426	18	and	and	CC
cord-256444-grw5s2pf	426	19	in	in	IN
cord-256444-grw5s2pf	426	20	regard	regard	NN
cord-256444-grw5s2pf	426	21	to	to	IN
cord-256444-grw5s2pf	426	22	the	the	DT
cord-256444-grw5s2pf	426	23	number	number	NN
cord-256444-grw5s2pf	426	24	of	of	IN
cord-256444-grw5s2pf	426	25	ORFs	orfs	NN
cord-256444-grw5s2pf	426	26	within	within	IN
cord-256444-grw5s2pf	426	27	a	a	DT
cord-256444-grw5s2pf	426	28	gene	gene	NN
cord-256444-grw5s2pf	426	29	(	(	-LRB-
cord-256444-grw5s2pf	426	30	Fig	Fig	NNP
cord-256444-grw5s2pf	426	31	.	.	.
cord-256444-grw5s2pf	426	32	5	5	CD
cord-256444-grw5s2pf	426	33	)	)	-RRB-
cord-256444-grw5s2pf	426	34	.	.	.
cord-256444-grw5s2pf	427	1	The	the	DT
cord-256444-grw5s2pf	427	2	functions	function	NNS
cord-256444-grw5s2pf	427	3	of	of	IN
cord-256444-grw5s2pf	427	4	these	these	DT
cord-256444-grw5s2pf	427	5	ns	ns	IN
cord-256444-grw5s2pf	427	6	proteins	protein	NNS
cord-256444-grw5s2pf	427	7	are	be	VBP
cord-256444-grw5s2pf	427	8	still	still	RB
cord-256444-grw5s2pf	427	9	unknown	unknown	JJ
cord-256444-grw5s2pf	427	10	.	.	.
cord-256444-grw5s2pf	428	1	There	there	EX
cord-256444-grw5s2pf	428	2	are	be	VBP
cord-256444-grw5s2pf	428	3	two	two	CD
cord-256444-grw5s2pf	428	4	genes	gene	NNS
cord-256444-grw5s2pf	428	5	located	locate	VBN
cord-256444-grw5s2pf	428	6	between	between	IN
cord-256444-grw5s2pf	428	7	the	the	DT
cord-256444-grw5s2pf	428	8	polymerase	polymerase	NN
cord-256444-grw5s2pf	428	9	and	and	CC
cord-256444-grw5s2pf	428	10	S	S	NNP
cord-256444-grw5s2pf	428	11	genes	gene	NNS
cord-256444-grw5s2pf	428	12	of	of	IN
cord-256444-grw5s2pf	428	13	these	these	DT
cord-256444-grw5s2pf	428	14	viruses	virus	NNS
cord-256444-grw5s2pf	428	15	(	(	-LRB-
cord-256444-grw5s2pf	428	16	Fig	fig	NN
cord-256444-grw5s2pf	428	17	.	.	NNP
cord-256444-grw5s2pf	428	18	5	5	CD
cord-256444-grw5s2pf	428	19	)	)	-RRB-
cord-256444-grw5s2pf	428	20	.	.	.
cord-256444-grw5s2pf	429	1	Gene	gene	NN
cord-256444-grw5s2pf	429	2	2	2	CD
cord-256444-grw5s2pf	429	3	-	-	SYM
cord-256444-grw5s2pf	429	4	1	1	CD
cord-256444-grw5s2pf	429	5	encodes	encode	VBZ
cord-256444-grw5s2pf	429	6	the	the	DT
cord-256444-grw5s2pf	429	7	HE	HE	NNP
cord-256444-grw5s2pf	429	8	protein	protein	NN
cord-256444-grw5s2pf	429	9	,	,	,
cord-256444-grw5s2pf	429	10	while	while	IN
cord-256444-grw5s2pf	429	11	gene	gene	NN
cord-256444-grw5s2pf	429	12	2	2	CD
cord-256444-grw5s2pf	429	13	encodes	encode	VBZ
cord-256444-grw5s2pf	429	14	an	an	DT
cord-256444-grw5s2pf	429	15	ns	ns	NNP
cord-256444-grw5s2pf	429	16	protein	protein	NN
cord-256444-grw5s2pf	429	17	of	of	IN
cord-256444-grw5s2pf	429	18	unknown	unknown	JJ
cord-256444-grw5s2pf	429	19	function	function	NN
cord-256444-grw5s2pf	429	20	.	.	.
cord-256444-grw5s2pf	430	1	The	the	DT
cord-256444-grw5s2pf	430	2	gene	gene	NN
cord-256444-grw5s2pf	430	3	2	2	CD
cord-256444-grw5s2pf	430	4	protein	protein	NN
cord-256444-grw5s2pf	430	5	com	com	NN
cord-256444-grw5s2pf	430	6	-	-	HYPH
cord-256444-grw5s2pf	430	7	prises	prise	NNS
cord-256444-grw5s2pf	430	8	approximately	approximately	RB
cord-256444-grw5s2pf	430	9	260	260	CD
cord-256444-grw5s2pf	430	10	amino	amino	JJ
cord-256444-grw5s2pf	430	11	acids	acid	NNS
cord-256444-grw5s2pf	430	12	(	(	-LRB-
cord-256444-grw5s2pf	430	13	30	30	CD
cord-256444-grw5s2pf	430	14	kDa	kDa	NNS
cord-256444-grw5s2pf	430	15	)	)	-RRB-
cord-256444-grw5s2pf	431	1	(	(	-LRB-
cord-256444-grw5s2pf	431	2	Luytjes	Luytjes	NNP
cord-256444-grw5s2pf	431	3	et	et	NNP
cord-256444-grw5s2pf	431	4	al	al	NNP
cord-256444-grw5s2pf	431	5	.	.	NNP
cord-256444-grw5s2pf	431	6	,	,	,
cord-256444-grw5s2pf	431	7	1988	1988	CD
cord-256444-grw5s2pf	432	1	;	;	:
cord-256444-grw5s2pf	432	2	Shieh	Shieh	NNP
cord-256444-grw5s2pf	432	3	et	et	NNP
cord-256444-grw5s2pf	432	4	al	al	NNP
cord-256444-grw5s2pf	432	5	.	.	NNP
cord-256444-grw5s2pf	432	6	,	,	,
cord-256444-grw5s2pf	432	7	1989	1989	CD
cord-256444-grw5s2pf	432	8	;	;	:
cord-256444-grw5s2pf	432	9	Labonte	Labonte	NNP
cord-256444-grw5s2pf	432	10	et	et	NNP
cord-256444-grw5s2pf	432	11	al	al	NNP
cord-256444-grw5s2pf	432	12	.	.	NNP
cord-256444-grw5s2pf	432	13	,	,	,
cord-256444-grw5s2pf	432	14	1995	1995	CD
cord-256444-grw5s2pf	432	15	)	)	-RRB-
cord-256444-grw5s2pf	432	16	.	.	.
cord-256444-grw5s2pf	433	1	The	the	DT
cord-256444-grw5s2pf	433	2	BCV	BCV	NNP
cord-256444-grw5s2pf	433	3	and	and	CC
cord-256444-grw5s2pf	433	4	MHV	MHV	NNP
cord-256444-grw5s2pf	433	5	homologs	homolog	NNS
cord-256444-grw5s2pf	433	6	share	share	VBP
cord-256444-grw5s2pf	433	7	45	45	CD
cord-256444-grw5s2pf	433	8	%	%	NN
cord-256444-grw5s2pf	433	9	amino	amino	NN
cord-256444-grw5s2pf	433	10	acid	acid	NN
cord-256444-grw5s2pf	433	11	identity	identity	NN
cord-256444-grw5s2pf	433	12	,	,	,
cord-256444-grw5s2pf	433	13	while	while	IN
cord-256444-grw5s2pf	433	14	the	the	DT
cord-256444-grw5s2pf	433	15	homolog	homolog	NN
cord-256444-grw5s2pf	433	16	of	of	IN
cord-256444-grw5s2pf	433	17	HCV	HCV	NNP
cord-256444-grw5s2pf	433	18	-	-	HYPH
cord-256444-grw5s2pf	433	19	OC43	OC43	NNP
cord-256444-grw5s2pf	433	20	has	have	VBZ
cord-256444-grw5s2pf	433	21	92	92	CD
cord-256444-grw5s2pf	433	22	%	%	NN
cord-256444-grw5s2pf	433	23	identity	identity	NN
cord-256444-grw5s2pf	433	24	with	with	IN
cord-256444-grw5s2pf	433	25	that	that	DT
cord-256444-grw5s2pf	433	26	of	of	IN
cord-256444-grw5s2pf	433	27	BCV	BCV	NNP
cord-256444-grw5s2pf	433	28	.	.	.
cord-256444-grw5s2pf	434	1	This	this	DT
cord-256444-grw5s2pf	434	2	gene	gene	NN
cord-256444-grw5s2pf	434	3	product	product	NN
cord-256444-grw5s2pf	434	4	has	have	VBZ
cord-256444-grw5s2pf	434	5	been	be	VBN
cord-256444-grw5s2pf	434	6	detected	detect	VBN
cord-256444-grw5s2pf	434	7	in	in	IN
cord-256444-grw5s2pf	434	8	the	the	DT
cord-256444-grw5s2pf	434	9	cytoplasm	cytoplasm	NN
cord-256444-grw5s2pf	434	10	of	of	IN
cord-256444-grw5s2pf	434	11	MHV-	MHV-	NNP
cord-256444-grw5s2pf	434	12	,	,	,
cord-256444-grw5s2pf	434	13	BCV-	BCV-	NNP
cord-256444-grw5s2pf	434	14	,	,	,
cord-256444-grw5s2pf	434	15	and	and	CC
cord-256444-grw5s2pf	434	16	HCV	HCV	NNP
cord-256444-grw5s2pf	434	17	-	-	HYPH
cord-256444-grw5s2pf	434	18	OC43-infected	OC43-infected	NNP
cord-256444-grw5s2pf	434	19	cells	cell	NNS
cord-256444-grw5s2pf	434	20	and	and	CC
cord-256444-grw5s2pf	434	21	may	may	MD
cord-256444-grw5s2pf	434	22	be	be	VB
cord-256444-grw5s2pf	434	23	phosphorylated	phosphorylate	VBN
cord-256444-grw5s2pf	435	1	(	(	-LRB-
cord-256444-grw5s2pf	435	2	Bredenbeek	Bredenbeek	NNP
cord-256444-grw5s2pf	435	3	et	et	NNP
cord-256444-grw5s2pf	435	4	al	al	NNP
cord-256444-grw5s2pf	435	5	.	.	NNP
cord-256444-grw5s2pf	435	6	,	,	,
cord-256444-grw5s2pf	435	7	1990	1990	CD
cord-256444-grw5s2pf	435	8	;	;	:
cord-256444-grw5s2pf	436	1	Zoltick	Zoltick	NNP
cord-256444-grw5s2pf	436	2	et	et	NNP
cord-256444-grw5s2pf	436	3	al	al	NNP
cord-256444-grw5s2pf	436	4	.	.	NNP
cord-256444-grw5s2pf	436	5	,	,	,
cord-256444-grw5s2pf	436	6	1990	1990	CD
cord-256444-grw5s2pf	436	7	;	;	:
cord-256444-grw5s2pf	437	1	Coxet	Coxet	NNP
cord-256444-grw5s2pf	437	2	al	al	NNP
cord-256444-grw5s2pf	437	3	.	.	NNP
cord-256444-grw5s2pf	437	4	,	,	,
cord-256444-grw5s2pf	437	5	1991	1991	CD
cord-256444-grw5s2pf	437	6	;	;	:
cord-256444-grw5s2pf	437	7	Labonte	Labonte	NNP
cord-256444-grw5s2pf	437	8	et	et	NNP
cord-256444-grw5s2pf	437	9	al	al	NNP
cord-256444-grw5s2pf	437	10	.	.	NNP
cord-256444-grw5s2pf	437	11	,	,	,
cord-256444-grw5s2pf	437	12	1995	1995	CD
cord-256444-grw5s2pf	437	13	)	)	-RRB-
cord-256444-grw5s2pf	437	14	.	.	.
cord-256444-grw5s2pf	438	1	Computer	computer	NN
cord-256444-grw5s2pf	438	2	analysis	analysis	NN
cord-256444-grw5s2pf	438	3	of	of	IN
cord-256444-grw5s2pf	438	4	its	-PRON-	PRP$
cord-256444-grw5s2pf	438	5	sequence	sequence	NN
cord-256444-grw5s2pf	438	6	suggested	suggest	VBD
cord-256444-grw5s2pf	438	7	the	the	DT
cord-256444-grw5s2pf	438	8	presence	presence	NN
cord-256444-grw5s2pf	438	9	of	of	IN
cord-256444-grw5s2pf	438	10	a	a	DT
cord-256444-grw5s2pf	438	11	nucleotide	nucleotide	NN
cord-256444-grw5s2pf	438	12	-	-	HYPH
cord-256444-grw5s2pf	438	13	binding	bind	VBG
cord-256444-grw5s2pf	438	14	site	site	NN
cord-256444-grw5s2pf	438	15	(	(	-LRB-
cord-256444-grw5s2pf	438	16	Luytjes	Luytjes	NNP
cord-256444-grw5s2pf	438	17	et	et	NNP
cord-256444-grw5s2pf	438	18	al	al	NNP
cord-256444-grw5s2pf	438	19	.	.	NNP
cord-256444-grw5s2pf	438	20	,	,	,
cord-256444-grw5s2pf	438	21	1988	1988	CD
cord-256444-grw5s2pf	438	22	)	)	-RRB-
cord-256444-grw5s2pf	438	23	.	.	.
cord-256444-grw5s2pf	439	1	However	however	RB
cord-256444-grw5s2pf	439	2	,	,	,
cord-256444-grw5s2pf	439	3	no	no	DT
cord-256444-grw5s2pf	439	4	function	function	NN
cord-256444-grw5s2pf	439	5	has	have	VBZ
cord-256444-grw5s2pf	439	6	been	be	VBN
cord-256444-grw5s2pf	439	7	assigned	assign	VBN
cord-256444-grw5s2pf	439	8	to	to	IN
cord-256444-grw5s2pf	439	9	this	this	DT
cord-256444-grw5s2pf	439	10	protein	protein	NN
cord-256444-grw5s2pf	439	11	,	,	,
cord-256444-grw5s2pf	439	12	and	and	CC
cord-256444-grw5s2pf	439	13	it	-PRON-	PRP
cord-256444-grw5s2pf	439	14	is	be	VBZ
cord-256444-grw5s2pf	439	15	not	not	RB
cord-256444-grw5s2pf	439	16	required	require	VBN
cord-256444-grw5s2pf	439	17	for	for	IN
cord-256444-grw5s2pf	439	18	virus	virus	NN
cord-256444-grw5s2pf	439	19	replication	replication	NN
cord-256444-grw5s2pf	439	20	in	in	IN
cord-256444-grw5s2pf	439	21	culture	culture	NN
cord-256444-grw5s2pf	439	22	(	(	-LRB-
cord-256444-grw5s2pf	440	1	Schwarz	Schwarz	NNP
cord-256444-grw5s2pf	440	2	et	et	NNP
cord-256444-grw5s2pf	440	3	al	al	NNP
cord-256444-grw5s2pf	440	4	.	.	NNP
cord-256444-grw5s2pf	440	5	,	,	,
cord-256444-grw5s2pf	440	6	1990	1990	CD
cord-256444-grw5s2pf	440	7	)	)	-RRB-
cord-256444-grw5s2pf	440	8	.	.	.
cord-256444-grw5s2pf	441	1	Interestingly	interestingly	RB
cord-256444-grw5s2pf	441	2	,	,	,
cord-256444-grw5s2pf	441	3	the	the	DT
cord-256444-grw5s2pf	441	4	C	C	NNP
cord-256444-grw5s2pf	441	5	terminus	terminus	NN
cord-256444-grw5s2pf	441	6	of	of	IN
cord-256444-grw5s2pf	441	7	the	the	DT
cord-256444-grw5s2pf	441	8	torovirus	torovirus	NNP
cord-256444-grw5s2pf	441	9	ORF	ORF	NNP
cord-256444-grw5s2pf	441	10	l	l	NNP
cord-256444-grw5s2pf	441	11	a	a	DT
cord-256444-grw5s2pf	441	12	product	product	NN
cord-256444-grw5s2pf	441	13	(	(	-LRB-
cord-256444-grw5s2pf	441	14	polymerase	polymerase	NN
cord-256444-grw5s2pf	441	15	)	)	-RRB-
cord-256444-grw5s2pf	441	16	has	have	VBZ
cord-256444-grw5s2pf	441	17	31	31	CD
cord-256444-grw5s2pf	441	18	-	-	SYM
cord-256444-grw5s2pf	441	19	36	36	CD
cord-256444-grw5s2pf	441	20	%	%	NN
cord-256444-grw5s2pf	441	21	sequence	sequence	NN
cord-256444-grw5s2pf	441	22	identity	identity	NN
cord-256444-grw5s2pf	441	23	with	with	IN
cord-256444-grw5s2pf	441	24	the	the	DT
cord-256444-grw5s2pf	441	25	gene	gene	NN
cord-256444-grw5s2pf	441	26	2	2	CD
cord-256444-grw5s2pf	441	27	product	product	NN
cord-256444-grw5s2pf	441	28	of	of	IN
cord-256444-grw5s2pf	441	29	MHV	MHV	NNP
cord-256444-grw5s2pf	441	30	(	(	-LRB-
cord-256444-grw5s2pf	441	31	Snijder	Snijder	NNP
cord-256444-grw5s2pf	441	32	et	et	NNP
cord-256444-grw5s2pf	441	33	al	al	NNP
cord-256444-grw5s2pf	441	34	.	.	NNP
cord-256444-grw5s2pf	441	35	,	,	,
cord-256444-grw5s2pf	441	36	1991	1991	CD
cord-256444-grw5s2pf	441	37	)	)	-RRB-
cord-256444-grw5s2pf	441	38	.	.	.
cord-256444-grw5s2pf	442	1	This	this	DT
cord-256444-grw5s2pf	442	2	evolutionary	evolutionary	JJ
cord-256444-grw5s2pf	442	3	relationship	relationship	NN
cord-256444-grw5s2pf	442	4	between	between	IN
cord-256444-grw5s2pf	442	5	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	442	6	and	and	CC
cord-256444-grw5s2pf	442	7	torovirus	torovirus	NNP
cord-256444-grw5s2pf	442	8	suggests	suggest	VBZ
cord-256444-grw5s2pf	442	9	that	that	IN
cord-256444-grw5s2pf	442	10	the	the	DT
cord-256444-grw5s2pf	442	11	gene	gene	NN
cord-256444-grw5s2pf	442	12	2	2	CD
cord-256444-grw5s2pf	442	13	product	product	NN
cord-256444-grw5s2pf	442	14	is	be	VBZ
cord-256444-grw5s2pf	442	15	probably	probably	RB
cord-256444-grw5s2pf	442	16	involved	involve	VBN
cord-256444-grw5s2pf	442	17	in	in	IN
cord-256444-grw5s2pf	442	18	viral	viral	JJ
cord-256444-grw5s2pf	442	19	RNA	RNA	NNP
cord-256444-grw5s2pf	442	20	synthesis	synthesis	NN
cord-256444-grw5s2pf	442	21	,	,	,
cord-256444-grw5s2pf	442	22	since	since	IN
cord-256444-grw5s2pf	442	23	it	-PRON-	PRP
cord-256444-grw5s2pf	442	24	is	be	VBZ
cord-256444-grw5s2pf	442	25	expressed	express	VBN
cord-256444-grw5s2pf	442	26	as	as	IN
cord-256444-grw5s2pf	442	27	part	part	NN
cord-256444-grw5s2pf	442	28	of	of	IN
cord-256444-grw5s2pf	442	29	the	the	DT
cord-256444-grw5s2pf	442	30	torovirus	torovirus	NNP
cord-256444-grw5s2pf	442	31	polymerases	polymerase	NNS
cord-256444-grw5s2pf	442	32	.	.	.
cord-256444-grw5s2pf	443	1	There	there	EX
cord-256444-grw5s2pf	443	2	are	be	VBP
cord-256444-grw5s2pf	443	3	two	two	CD
cord-256444-grw5s2pf	443	4	to	to	TO
cord-256444-grw5s2pf	443	5	three	three	CD
cord-256444-grw5s2pf	443	6	ORFs	orf	NNS
cord-256444-grw5s2pf	443	7	in	in	IN
cord-256444-grw5s2pf	443	8	this	this	DT
cord-256444-grw5s2pf	443	9	region	region	NN
cord-256444-grw5s2pf	443	10	,	,	,
cord-256444-grw5s2pf	443	11	and	and	CC
cord-256444-grw5s2pf	443	12	their	-PRON-	PRP$
cord-256444-grw5s2pf	443	13	structure	structure	NN
cord-256444-grw5s2pf	443	14	and	and	CC
cord-256444-grw5s2pf	443	15	the	the	DT
cord-256444-grw5s2pf	443	16	mechanism	mechanism	NN
cord-256444-grw5s2pf	443	17	of	of	IN
cord-256444-grw5s2pf	443	18	expression	expression	NN
cord-256444-grw5s2pf	443	19	of	of	IN
cord-256444-grw5s2pf	443	20	gene	gene	NN
cord-256444-grw5s2pf	443	21	products	product	NNS
cord-256444-grw5s2pf	443	22	vary	vary	VBP
cord-256444-grw5s2pf	443	23	markedly	markedly	RB
cord-256444-grw5s2pf	443	24	among	among	IN
cord-256444-grw5s2pf	443	25	different	different	JJ
cord-256444-grw5s2pf	443	26	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	443	27	species	specie	NNS
cord-256444-grw5s2pf	443	28	.	.	.
cord-256444-grw5s2pf	444	1	They	-PRON-	PRP
cord-256444-grw5s2pf	444	2	can	can	MD
cord-256444-grw5s2pf	444	3	be	be	VB
cord-256444-grw5s2pf	444	4	expressed	express	VBN
cord-256444-grw5s2pf	444	5	as	as	IN
cord-256444-grw5s2pf	444	6	two	two	CD
cord-256444-grw5s2pf	444	7	different	different	JJ
cord-256444-grw5s2pf	444	8	genes	gene	NNS
cord-256444-grw5s2pf	444	9	,	,	,
cord-256444-grw5s2pf	444	10	i.e.	i.e.	FW
cord-256444-grw5s2pf	444	11	,	,	,
cord-256444-grw5s2pf	444	12	expressed	express	VBN
cord-256444-grw5s2pf	444	13	from	from	IN
cord-256444-grw5s2pf	444	14	two	two	CD
cord-256444-grw5s2pf	444	15	separate	separate	JJ
cord-256444-grw5s2pf	444	16	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	444	17	(	(	-LRB-
cord-256444-grw5s2pf	444	18	e.g.	e.g.	RB
cord-256444-grw5s2pf	444	19	,	,	,
cord-256444-grw5s2pf	444	20	mRNAs	mrnas	CD
cord-256444-grw5s2pf	444	21	4	4	CD
cord-256444-grw5s2pf	444	22	and	and	CC
cord-256444-grw5s2pf	444	23	5	5	CD
cord-256444-grw5s2pf	444	24	of	of	IN
cord-256444-grw5s2pf	444	25	MHV	MHV	NNP
cord-256444-grw5s2pf	444	26	and	and	CC
cord-256444-grw5s2pf	444	27	BCV	BCV	NNP
cord-256444-grw5s2pf	444	28	and	and	CC
cord-256444-grw5s2pf	444	29	mRNAs	mrnas	CD
cord-256444-grw5s2pf	444	30	3	3	CD
cord-256444-grw5s2pf	444	31	and	and	CC
cord-256444-grw5s2pf	444	32	3	3	CD
cord-256444-grw5s2pf	444	33	-	-	SYM
cord-256444-grw5s2pf	444	34	1	1	CD
cord-256444-grw5s2pf	444	35	of	of	IN
cord-256444-grw5s2pf	444	36	TGEV	TGEV	NNP
cord-256444-grw5s2pf	444	37	)	)	-RRB-
cord-256444-grw5s2pf	444	38	or	or	CC
cord-256444-grw5s2pf	444	39	localized	localize	VBN
cord-256444-grw5s2pf	444	40	in	in	IN
cord-256444-grw5s2pf	444	41	one	one	CD
cord-256444-grw5s2pf	444	42	gene	gene	NN
cord-256444-grw5s2pf	444	43	,	,	,
cord-256444-grw5s2pf	444	44	thus	thus	RB
cord-256444-grw5s2pf	444	45	requiring	require	VBG
cord-256444-grw5s2pf	444	46	internal	internal	JJ
cord-256444-grw5s2pf	444	47	initiation	initiation	NN
cord-256444-grw5s2pf	444	48	of	of	IN
cord-256444-grw5s2pf	444	49	translation	translation	NN
cord-256444-grw5s2pf	444	50	from	from	IN
cord-256444-grw5s2pf	444	51	a	a	DT
cord-256444-grw5s2pf	444	52	single	single	JJ
cord-256444-grw5s2pf	444	53	polycistronic	polycistronic	NN
cord-256444-grw5s2pf	444	54	mRNA	mrna	NN
cord-256444-grw5s2pf	445	1	(	(	-LRB-
cord-256444-grw5s2pf	445	2	e.g.	e.g.	RB
cord-256444-grw5s2pf	445	3	,	,	,
cord-256444-grw5s2pf	445	4	mRNA	mRNA	NNP
cord-256444-grw5s2pf	445	5	3	3	CD
cord-256444-grw5s2pf	445	6	of	of	IN
cord-256444-grw5s2pf	445	7	the	the	DT
cord-256444-grw5s2pf	445	8	IBV	IBV	NNP
cord-256444-grw5s2pf	445	9	and	and	CC
cord-256444-grw5s2pf	445	10	FCV	FCV	NNP
cord-256444-grw5s2pf	445	11	groups	group	NNS
cord-256444-grw5s2pf	445	12	)	)	-RRB-
cord-256444-grw5s2pf	445	13	.	.	.
cord-256444-grw5s2pf	446	1	In	in	IN
cord-256444-grw5s2pf	446	2	IBV	IBV	NNP
cord-256444-grw5s2pf	446	3	,	,	,
cord-256444-grw5s2pf	446	4	it	-PRON-	PRP
cord-256444-grw5s2pf	446	5	contains	contain	VBZ
cord-256444-grw5s2pf	446	6	three	three	CD
cord-256444-grw5s2pf	446	7	ORFs	ORFs	NNP
cord-256444-grw5s2pf	446	8	(	(	-LRB-
cord-256444-grw5s2pf	446	9	3a	3a	NNP
cord-256444-grw5s2pf	446	10	,	,	,
cord-256444-grw5s2pf	446	11	3b	3b	NNP
cord-256444-grw5s2pf	446	12	,	,	,
cord-256444-grw5s2pf	446	13	and	and	CC
cord-256444-grw5s2pf	446	14	3c	3c	NNP
cord-256444-grw5s2pf	446	15	)	)	-RRB-
cord-256444-grw5s2pf	446	16	;	;	:
cord-256444-grw5s2pf	446	17	ORF	ORF	NNP
cord-256444-grw5s2pf	446	18	3c	3c	NNP
cord-256444-grw5s2pf	446	19	encodes	encode	VBZ
cord-256444-grw5s2pf	446	20	the	the	DT
cord-256444-grw5s2pf	446	21	E	e	NN
cord-256444-grw5s2pf	446	22	protein	protein	NN
cord-256444-grw5s2pf	446	23	,	,	,
cord-256444-grw5s2pf	446	24	which	which	WDT
cord-256444-grw5s2pf	446	25	is	be	VBZ
cord-256444-grw5s2pf	446	26	a	a	DT
cord-256444-grw5s2pf	446	27	viral	viral	JJ
cord-256444-grw5s2pf	446	28	structural	structural	JJ
cord-256444-grw5s2pf	446	29	protein	protein	NN
cord-256444-grw5s2pf	446	30	,	,	,
cord-256444-grw5s2pf	446	31	while	while	IN
cord-256444-grw5s2pf	446	32	3a	3a	NNP
cord-256444-grw5s2pf	446	33	and	and	CC
cord-256444-grw5s2pf	446	34	3b	3b	NNP
cord-256444-grw5s2pf	446	35	encode	encode	VB
cord-256444-grw5s2pf	446	36	ns	ns	IN
cord-256444-grw5s2pf	446	37	proteins	protein	NNS
cord-256444-grw5s2pf	446	38	.	.	.
cord-256444-grw5s2pf	447	1	The	the	DT
cord-256444-grw5s2pf	447	2	gene	gene	NN
cord-256444-grw5s2pf	447	3	products	product	NNS
cord-256444-grw5s2pf	447	4	of	of	IN
cord-256444-grw5s2pf	447	5	both	both	DT
cord-256444-grw5s2pf	447	6	ORFs	ORFs	NNP
cord-256444-grw5s2pf	447	7	3a	3a	NN
cord-256444-grw5s2pf	447	8	and	and	CC
cord-256444-grw5s2pf	447	9	3b	3b	NNP
cord-256444-grw5s2pf	447	10	(	(	-LRB-
cord-256444-grw5s2pf	447	11	approximately	approximately	RB
cord-256444-grw5s2pf	447	12	7	7	CD
cord-256444-grw5s2pf	447	13	kDa	kDa	NNS
cord-256444-grw5s2pf	447	14	)	)	-RRB-
cord-256444-grw5s2pf	447	15	have	have	VBP
cord-256444-grw5s2pf	447	16	been	be	VBN
cord-256444-grw5s2pf	447	17	detected	detect	VBN
cord-256444-grw5s2pf	447	18	in	in	IN
cord-256444-grw5s2pf	447	19	small	small	JJ
cord-256444-grw5s2pf	447	20	quantities	quantity	NNS
cord-256444-grw5s2pf	447	21	in	in	IN
cord-256444-grw5s2pf	447	22	virus	virus	NN
cord-256444-grw5s2pf	447	23	-	-	HYPH
cord-256444-grw5s2pf	447	24	infected	infect	VBN
cord-256444-grw5s2pf	447	25	cells	cell	NNS
cord-256444-grw5s2pf	447	26	(	(	-LRB-
cord-256444-grw5s2pf	447	27	Liu	Liu	NNP
cord-256444-grw5s2pf	447	28	et	et	NNP
cord-256444-grw5s2pf	447	29	al	al	NNP
cord-256444-grw5s2pf	447	30	.	.	NNP
cord-256444-grw5s2pf	447	31	,	,	,
cord-256444-grw5s2pf	447	32	1991	1991	CD
cord-256444-grw5s2pf	447	33	)	)	-RRB-
cord-256444-grw5s2pf	447	34	.	.	.
cord-256444-grw5s2pf	448	1	In	in	IN
cord-256444-grw5s2pf	448	2	TGEV	TGEV	NNP
cord-256444-grw5s2pf	448	3	,	,	,
cord-256444-grw5s2pf	448	4	this	this	DT
cord-256444-grw5s2pf	448	5	region	region	NN
cord-256444-grw5s2pf	448	6	contains	contain	VBZ
cord-256444-grw5s2pf	448	7	two	two	CD
cord-256444-grw5s2pf	448	8	ORFs	orf	NNS
cord-256444-grw5s2pf	448	9	,	,	,
cord-256444-grw5s2pf	448	10	being	be	VBG
cord-256444-grw5s2pf	448	11	separated	separate	VBN
cord-256444-grw5s2pf	448	12	from	from	IN
cord-256444-grw5s2pf	448	13	the	the	DT
cord-256444-grw5s2pf	448	14	E	e	NN
cord-256444-grw5s2pf	448	15	protein	protein	NN
cord-256444-grw5s2pf	448	16	gene	gene	NN
cord-256444-grw5s2pf	448	17	.	.	.
cord-256444-grw5s2pf	449	1	These	these	DT
cord-256444-grw5s2pf	449	2	two	two	CD
cord-256444-grw5s2pf	449	3	ORFs	orf	NNS
cord-256444-grw5s2pf	449	4	are	be	VBP
cord-256444-grw5s2pf	449	5	encoded	encode	VBN
cord-256444-grw5s2pf	449	6	by	by	IN
cord-256444-grw5s2pf	449	7	mRNAs	mrnas	CD
cord-256444-grw5s2pf	449	8	3	3	CD
cord-256444-grw5s2pf	449	9	and	and	CC
cord-256444-grw5s2pf	449	10	3	3	CD
cord-256444-grw5s2pf	449	11	-	-	SYM
cord-256444-grw5s2pf	449	12	1	1	CD
cord-256444-grw5s2pf	449	13	,	,	,
cord-256444-grw5s2pf	449	14	respectively	respectively	RB
cord-256444-grw5s2pf	449	15	,	,	,
cord-256444-grw5s2pf	449	16	the	the	DT
cord-256444-grw5s2pf	449	17	predicted	predict	VBN
cord-256444-grw5s2pf	449	18	protein	protein	NN
cord-256444-grw5s2pf	449	19	products	product	NNS
cord-256444-grw5s2pf	449	20	being	be	VBG
cord-256444-grw5s2pf	449	21	approximately	approximately	RB
cord-256444-grw5s2pf	449	22	8	8	CD
cord-256444-grw5s2pf	449	23	and	and	CC
cord-256444-grw5s2pf	449	24	27	27	CD
cord-256444-grw5s2pf	449	25	kDa	kDa	NNS
cord-256444-grw5s2pf	449	26	,	,	,
cord-256444-grw5s2pf	449	27	respectively	respectively	RB
cord-256444-grw5s2pf	449	28	.	.	.
cord-256444-grw5s2pf	450	1	In	in	IN
cord-256444-grw5s2pf	450	2	a	a	DT
cord-256444-grw5s2pf	450	3	related	relate	VBN
cord-256444-grw5s2pf	450	4	nonenterogenic	nonenterogenic	JJ
cord-256444-grw5s2pf	450	5	strain	strain	NN
cord-256444-grw5s2pf	450	6	,	,	,
cord-256444-grw5s2pf	450	7	PRCV	PRCV	NNP
cord-256444-grw5s2pf	450	8	,	,	,
cord-256444-grw5s2pf	450	9	however	however	RB
cord-256444-grw5s2pf	450	10	,	,	,
cord-256444-grw5s2pf	450	11	there	there	EX
cord-256444-grw5s2pf	450	12	are	be	VBP
cord-256444-grw5s2pf	450	13	multiple	multiple	JJ
cord-256444-grw5s2pf	450	14	deletions	deletion	NNS
cord-256444-grw5s2pf	450	15	in	in	IN
cord-256444-grw5s2pf	450	16	this	this	DT
cord-256444-grw5s2pf	450	17	region	region	NN
cord-256444-grw5s2pf	450	18	,	,	,
cord-256444-grw5s2pf	450	19	essentially	essentially	RB
cord-256444-grw5s2pf	450	20	inactivating	inactivate	VBG
cord-256444-grw5s2pf	450	21	one	one	CD
cord-256444-grw5s2pf	450	22	or	or	CC
cord-256444-grw5s2pf	450	23	both	both	DT
cord-256444-grw5s2pf	450	24	of	of	IN
cord-256444-grw5s2pf	450	25	the	the	DT
cord-256444-grw5s2pf	450	26	ORFs	ORFs	NNP
cord-256444-grw5s2pf	450	27	(	(	-LRB-
cord-256444-grw5s2pf	450	28	Rasschaert	Rasschaert	NNP
cord-256444-grw5s2pf	450	29	et	et	FW
cord-256444-grw5s2pf	450	30	al	al	NNP
cord-256444-grw5s2pf	450	31	.	.	NNP
cord-256444-grw5s2pf	450	32	,	,	,
cord-256444-grw5s2pf	450	33	1990	1990	CD
cord-256444-grw5s2pf	450	34	;	;	:
cord-256444-grw5s2pf	451	1	Wesley	Wesley	NNP
cord-256444-grw5s2pf	451	2	et	et	NNP
cord-256444-grw5s2pf	451	3	al	al	NNP
cord-256444-grw5s2pf	451	4	.	.	NNP
cord-256444-grw5s2pf	451	5	,	,	,
cord-256444-grw5s2pf	451	6	1991	1991	CD
cord-256444-grw5s2pf	451	7	)	)	-RRB-
cord-256444-grw5s2pf	451	8	.	.	.
cord-256444-grw5s2pf	452	1	It	-PRON-	PRP
cord-256444-grw5s2pf	452	2	has	have	VBZ
cord-256444-grw5s2pf	452	3	been	be	VBN
cord-256444-grw5s2pf	452	4	suggested	suggest	VBN
cord-256444-grw5s2pf	452	5	that	that	IN
cord-256444-grw5s2pf	452	6	the	the	DT
cord-256444-grw5s2pf	452	7	absence	absence	NN
cord-256444-grw5s2pf	452	8	of	of	IN
cord-256444-grw5s2pf	452	9	the	the	DT
cord-256444-grw5s2pf	452	10	3a	3a	CD
cord-256444-grw5s2pf	452	11	product	product	NN
cord-256444-grw5s2pf	452	12	,	,	,
cord-256444-grw5s2pf	452	13	in	in	IN
cord-256444-grw5s2pf	452	14	addition	addition	NN
cord-256444-grw5s2pf	452	15	to	to	IN
cord-256444-grw5s2pf	452	16	a	a	DT
cord-256444-grw5s2pf	452	17	shorter	short	JJR
cord-256444-grw5s2pf	452	18	S	s	NN
cord-256444-grw5s2pf	452	19	protein	protein	NN
cord-256444-grw5s2pf	452	20	,	,	,
cord-256444-grw5s2pf	452	21	might	may	MD
cord-256444-grw5s2pf	452	22	be	be	VB
cord-256444-grw5s2pf	452	23	associated	associate	VBN
cord-256444-grw5s2pf	452	24	with	with	IN
cord-256444-grw5s2pf	452	25	their	-PRON-	PRP$
cord-256444-grw5s2pf	452	26	lack	lack	NN
cord-256444-grw5s2pf	452	27	of	of	IN
cord-256444-grw5s2pf	452	28	enteropathogenicity	enteropathogenicity	NN
cord-256444-grw5s2pf	452	29	.	.	.
cord-256444-grw5s2pf	453	1	However	however	RB
cord-256444-grw5s2pf	453	2	,	,	,
cord-256444-grw5s2pf	453	3	Vaughn	Vaughn	NNP
cord-256444-grw5s2pf	453	4	et	et	NNP
cord-256444-grw5s2pf	453	5	al	al	NNP
cord-256444-grw5s2pf	453	6	.	.	.
cord-256444-grw5s2pf	454	1	(	(	-LRB-
cord-256444-grw5s2pf	454	2	1995	1995	CD
cord-256444-grw5s2pf	454	3	)	)	-RRB-
cord-256444-grw5s2pf	454	4	have	have	VBP
cord-256444-grw5s2pf	454	5	recently	recently	RB
cord-256444-grw5s2pf	454	6	described	describe	VBN
cord-256444-grw5s2pf	454	7	two	two	CD
cord-256444-grw5s2pf	454	8	PRCV	PRCV	NNS
cord-256444-grw5s2pf	454	9	strains	strain	NNS
cord-256444-grw5s2pf	454	10	which	which	WDT
cord-256444-grw5s2pf	454	11	have	have	VBP
cord-256444-grw5s2pf	454	12	an	an	DT
cord-256444-grw5s2pf	454	13	intact	intact	JJ
cord-256444-grw5s2pf	454	14	3a	3a	CD
cord-256444-grw5s2pf	454	15	gene	gene	NN
cord-256444-grw5s2pf	454	16	(	(	-LRB-
cord-256444-grw5s2pf	454	17	Vaughn	Vaughn	NNP
cord-256444-grw5s2pf	454	18	et	et	NNP
cord-256444-grw5s2pf	454	19	al	al	NNP
cord-256444-grw5s2pf	454	20	.	.	NNP
cord-256444-grw5s2pf	454	21	,	,	,
cord-256444-grw5s2pf	454	22	1995	1995	CD
cord-256444-grw5s2pf	454	23	)	)	-RRB-
cord-256444-grw5s2pf	454	24	.	.	.
cord-256444-grw5s2pf	455	1	Canine	canine	JJ
cord-256444-grw5s2pf	455	2	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	455	3	has	have	VBZ
cord-256444-grw5s2pf	455	4	gene	gene	NN
cord-256444-grw5s2pf	455	5	3	3	CD
cord-256444-grw5s2pf	455	6	ORFs	orfs	NN
cord-256444-grw5s2pf	455	7	equivalent	equivalent	JJ
cord-256444-grw5s2pf	455	8	to	to	IN
cord-256444-grw5s2pf	455	9	those	those	DT
cord-256444-grw5s2pf	455	10	of	of	IN
cord-256444-grw5s2pf	455	11	TGEV	TGEV	NNP
cord-256444-grw5s2pf	455	12	,	,	,
cord-256444-grw5s2pf	455	13	exhibiting	exhibit	VBG
cord-256444-grw5s2pf	455	14	high	high	JJ
cord-256444-grw5s2pf	455	15	amino	amino	NN
cord-256444-grw5s2pf	455	16	acid	acid	NN
cord-256444-grw5s2pf	455	17	identity	identity	NN
cord-256444-grw5s2pf	455	18	(	(	-LRB-
cord-256444-grw5s2pf	455	19	>	>	NFP
cord-256444-grw5s2pf	455	20	80	80	CD
cord-256444-grw5s2pf	455	21	%	%	NN
cord-256444-grw5s2pf	455	22	)	)	-RRB-
cord-256444-grw5s2pf	455	23	,	,	,
cord-256444-grw5s2pf	455	24	although	although	IN
cord-256444-grw5s2pf	455	25	the	the	DT
cord-256444-grw5s2pf	455	26	second	second	JJ
cord-256444-grw5s2pf	455	27	ORF	ORF	NNP
cord-256444-grw5s2pf	455	28	is	be	VBZ
cord-256444-grw5s2pf	455	29	truncated	truncate	VBN
cord-256444-grw5s2pf	455	30	by	by	IN
cord-256444-grw5s2pf	455	31	a	a	DT
cord-256444-grw5s2pf	455	32	stop	stop	NN
cord-256444-grw5s2pf	455	33	codon	codon	NN
cord-256444-grw5s2pf	455	34	(	(	-LRB-
cord-256444-grw5s2pf	455	35	Horsburgh	Horsburgh	NNP
cord-256444-grw5s2pf	455	36	et	et	NNP
cord-256444-grw5s2pf	455	37	al	al	NNP
cord-256444-grw5s2pf	455	38	.	.	NNP
cord-256444-grw5s2pf	455	39	,	,	,
cord-256444-grw5s2pf	455	40	1992	1992	CD
cord-256444-grw5s2pf	455	41	)	)	-RRB-
cord-256444-grw5s2pf	455	42	.	.	.
cord-256444-grw5s2pf	456	1	Two	two	CD
cord-256444-grw5s2pf	456	2	other	other	JJ
cord-256444-grw5s2pf	456	3	members	member	NNS
cord-256444-grw5s2pf	456	4	of	of	IN
cord-256444-grw5s2pf	456	5	the	the	DT
cord-256444-grw5s2pf	456	6	TGEV	TGEV	NNP
cord-256444-grw5s2pf	456	7	group	group	NN
cord-256444-grw5s2pf	456	8	exhibit	exhibit	VBP
cord-256444-grw5s2pf	456	9	a	a	DT
cord-256444-grw5s2pf	456	10	variation	variation	NN
cord-256444-grw5s2pf	456	11	on	on	IN
cord-256444-grw5s2pf	456	12	the	the	DT
cord-256444-grw5s2pf	456	13	same	same	JJ
cord-256444-grw5s2pf	456	14	theme	theme	NN
cord-256444-grw5s2pf	456	15	.	.	.
cord-256444-grw5s2pf	457	1	PEDV	PEDV	NNP
cord-256444-grw5s2pf	457	2	and	and	CC
cord-256444-grw5s2pf	457	3	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	457	4	lack	lack	VBP
cord-256444-grw5s2pf	457	5	a	a	DT
cord-256444-grw5s2pf	457	6	homolg	homolg	NN
cord-256444-grw5s2pf	457	7	of	of	IN
cord-256444-grw5s2pf	457	8	ORF	ORF	NNP
cord-256444-grw5s2pf	457	9	3a	3a	NNP
cord-256444-grw5s2pf	457	10	of	of	IN
cord-256444-grw5s2pf	457	11	TGEV	TGEV	NNP
cord-256444-grw5s2pf	457	12	and	and	CC
cord-256444-grw5s2pf	457	13	CCV	CCV	NNP
cord-256444-grw5s2pf	457	14	.	.	.
cord-256444-grw5s2pf	458	1	PEDV	PEDV	NNP
cord-256444-grw5s2pf	458	2	has	have	VBZ
cord-256444-grw5s2pf	458	3	an	an	DT
cord-256444-grw5s2pf	458	4	ORF	ORF	NNP
cord-256444-grw5s2pf	458	5	corresponding	correspond	VBG
cord-256444-grw5s2pf	458	6	to	to	IN
cord-256444-grw5s2pf	458	7	3b	3b	CD
cord-256444-grw5s2pf	458	8	of	of	IN
cord-256444-grw5s2pf	458	9	TGEV	TGEV	NNP
cord-256444-grw5s2pf	458	10	,	,	,
cord-256444-grw5s2pf	458	11	while	while	IN
cord-256444-grw5s2pf	458	12	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	458	13	has	have	VBZ
cord-256444-grw5s2pf	458	14	two	two	CD
cord-256444-grw5s2pf	458	15	ORFs	orf	NNS
cord-256444-grw5s2pf	458	16	corresponding	correspond	VBG
cord-256444-grw5s2pf	458	17	to	to	IN
cord-256444-grw5s2pf	458	18	the	the	DT
cord-256444-grw5s2pf	458	19	single	single	JJ
cord-256444-grw5s2pf	458	20	ORF	ORF	NNP
cord-256444-grw5s2pf	458	21	of	of	IN
cord-256444-grw5s2pf	458	22	PEDV	PEDV	NNP
cord-256444-grw5s2pf	459	1	(	(	-LRB-
cord-256444-grw5s2pf	459	2	Duarte	Duarte	NNP
cord-256444-grw5s2pf	459	3	et	et	NNP
cord-256444-grw5s2pf	459	4	al	al	NNP
cord-256444-grw5s2pf	459	5	.	.	NNP
cord-256444-grw5s2pf	459	6	,	,	,
cord-256444-grw5s2pf	459	7	1994	1994	CD
cord-256444-grw5s2pf	459	8	)	)	-RRB-
cord-256444-grw5s2pf	459	9	.	.	.
cord-256444-grw5s2pf	460	1	Members	member	NNS
cord-256444-grw5s2pf	460	2	of	of	IN
cord-256444-grw5s2pf	460	3	the	the	DT
cord-256444-grw5s2pf	460	4	group	group	NN
cord-256444-grw5s2pf	460	5	I	-PRON-	PRP
cord-256444-grw5s2pf	460	6	coronaviruses	coronaviruse	VBZ
cord-256444-grw5s2pf	460	7	also	also	RB
cord-256444-grw5s2pf	460	8	exhibit	exhibit	VBP
cord-256444-grw5s2pf	460	9	great	great	JJ
cord-256444-grw5s2pf	460	10	heterogeneity	heterogeneity	NN
cord-256444-grw5s2pf	460	11	in	in	IN
cord-256444-grw5s2pf	460	12	this	this	DT
cord-256444-grw5s2pf	460	13	region	region	NN
cord-256444-grw5s2pf	460	14	.	.	.
cord-256444-grw5s2pf	461	1	MHV	MHV	NNP
cord-256444-grw5s2pf	461	2	-	-	HYPH
cord-256444-grw5s2pf	461	3	JHM	JHM	NNP
cord-256444-grw5s2pf	461	4	produces	produce	VBZ
cord-256444-grw5s2pf	461	5	mRNA	mRNA	NNP
cord-256444-grw5s2pf	461	6	4	4	CD
cord-256444-grw5s2pf	461	7	,	,	,
cord-256444-grw5s2pf	461	8	which	which	WDT
cord-256444-grw5s2pf	461	9	encodes	encode	VBZ
cord-256444-grw5s2pf	461	10	a	a	DT
cord-256444-grw5s2pf	461	11	15-kDa	15-kda	CD
cord-256444-grw5s2pf	461	12	protein	protein	NN
cord-256444-grw5s2pf	461	13	.	.	.
cord-256444-grw5s2pf	462	1	This	this	DT
cord-256444-grw5s2pf	462	2	protein	protein	NN
cord-256444-grw5s2pf	462	3	has	have	VBZ
cord-256444-grw5s2pf	462	4	been	be	VBN
cord-256444-grw5s2pf	462	5	detected	detect	VBN
cord-256444-grw5s2pf	462	6	in	in	IN
cord-256444-grw5s2pf	462	7	virus	virus	NN
cord-256444-grw5s2pf	462	8	-	-	HYPH
cord-256444-grw5s2pf	462	9	infected	infect	VBN
cord-256444-grw5s2pf	462	10	cells	cell	NNS
cord-256444-grw5s2pf	462	11	(	(	-LRB-
cord-256444-grw5s2pf	462	12	Ebner	Ebner	NNP
cord-256444-grw5s2pf	462	13	et	et	NNP
cord-256444-grw5s2pf	462	14	al	al	NNP
cord-256444-grw5s2pf	462	15	.	.	NNP
cord-256444-grw5s2pf	462	16	,	,	,
cord-256444-grw5s2pf	462	17	1988	1988	CD
cord-256444-grw5s2pf	462	18	)	)	-RRB-
cord-256444-grw5s2pf	462	19	.	.	.
cord-256444-grw5s2pf	463	1	In	in	IN
cord-256444-grw5s2pf	463	2	contrast	contrast	NN
cord-256444-grw5s2pf	463	3	,	,	,
cord-256444-grw5s2pf	463	4	HCV	HCV	NNP
cord-256444-grw5s2pf	463	5	-	-	HYPH
cord-256444-grw5s2pf	463	6	OC43	OC43	NNP
cord-256444-grw5s2pf	463	7	contains	contain	VBZ
cord-256444-grw5s2pf	463	8	only	only	RB
cord-256444-grw5s2pf	463	9	11	11	CD
cord-256444-grw5s2pf	463	10	amino	amino	NN
cord-256444-grw5s2pf	463	11	acids	acid	NNS
cord-256444-grw5s2pf	463	12	in	in	IN
cord-256444-grw5s2pf	463	13	this	this	DT
cord-256444-grw5s2pf	463	14	region	region	NN
cord-256444-grw5s2pf	463	15	(	(	-LRB-
cord-256444-grw5s2pf	463	16	Mounir	Mounir	NNP
cord-256444-grw5s2pf	463	17	and	and	CC
cord-256444-grw5s2pf	463	18	Talbot	Talbot	NNP
cord-256444-grw5s2pf	463	19	,	,	,
cord-256444-grw5s2pf	463	20	1993	1993	CD
cord-256444-grw5s2pf	463	21	)	)	-RRB-
cord-256444-grw5s2pf	463	22	.	.	.
cord-256444-grw5s2pf	464	1	Gene	gene	NN
cord-256444-grw5s2pf	464	2	5	5	CD
cord-256444-grw5s2pf	464	3	of	of	IN
cord-256444-grw5s2pf	464	4	MHV	MHV	NNP
cord-256444-grw5s2pf	464	5	has	have	VBZ
cord-256444-grw5s2pf	464	6	two	two	CD
cord-256444-grw5s2pf	464	7	ORFs	orf	NNS
cord-256444-grw5s2pf	464	8	,	,	,
cord-256444-grw5s2pf	464	9	5a	5a	CD
cord-256444-grw5s2pf	464	10	and	and	CC
cord-256444-grw5s2pf	464	11	5b	5b	NN
cord-256444-grw5s2pf	464	12	.	.	.
cord-256444-grw5s2pf	465	1	The	the	DT
cord-256444-grw5s2pf	465	2	latter	latter	NN
cord-256444-grw5s2pf	465	3	encodes	encode	VBZ
cord-256444-grw5s2pf	465	4	the	the	DT
cord-256444-grw5s2pf	465	5	structural	structural	JJ
cord-256444-grw5s2pf	465	6	E	e	NN
cord-256444-grw5s2pf	465	7	protein	protein	NN
cord-256444-grw5s2pf	465	8	and	and	CC
cord-256444-grw5s2pf	465	9	is	be	VBZ
cord-256444-grw5s2pf	465	10	the	the	DT
cord-256444-grw5s2pf	465	11	predominant	predominant	JJ
cord-256444-grw5s2pf	465	12	product	product	NN
cord-256444-grw5s2pf	465	13	made	make	VBN
cord-256444-grw5s2pf	465	14	from	from	IN
cord-256444-grw5s2pf	465	15	mRNA	mRNA	NNP
cord-256444-grw5s2pf	465	16	5	5	CD
cord-256444-grw5s2pf	465	17	.	.	.
cord-256444-grw5s2pf	466	1	It	-PRON-	PRP
cord-256444-grw5s2pf	466	2	is	be	VBZ
cord-256444-grw5s2pf	466	3	not	not	RB
cord-256444-grw5s2pf	466	4	clear	clear	JJ
cord-256444-grw5s2pf	466	5	whether	whether	IN
cord-256444-grw5s2pf	466	6	ORF	ORF	NNP
cord-256444-grw5s2pf	466	7	5a	5a	CD
cord-256444-grw5s2pf	466	8	is	be	VBZ
cord-256444-grw5s2pf	466	9	translated	translate	VBN
cord-256444-grw5s2pf	466	10	at	at	RB
cord-256444-grw5s2pf	466	11	all	all	RB
cord-256444-grw5s2pf	466	12	.	.	.
cord-256444-grw5s2pf	467	1	At	at	RB
cord-256444-grw5s2pf	467	2	least	least	RBS
cord-256444-grw5s2pf	467	3	one	one	CD
cord-256444-grw5s2pf	467	4	strain	strain	NN
cord-256444-grw5s2pf	467	5	of	of	IN
cord-256444-grw5s2pf	467	6	MHV	MHV	NNP
cord-256444-grw5s2pf	467	7	lacks	lack	VBZ
cord-256444-grw5s2pf	467	8	the	the	DT
cord-256444-grw5s2pf	467	9	5a	5a	CD
cord-256444-grw5s2pf	467	10	ORF	ORF	NNP
cord-256444-grw5s2pf	467	11	;	;	:
cord-256444-grw5s2pf	467	12	also	also	RB
cord-256444-grw5s2pf	467	13	,	,	,
cord-256444-grw5s2pf	467	14	HCV	HCV	NNP
cord-256444-grw5s2pf	467	15	-	-	HYPH
cord-256444-grw5s2pf	467	16	OC43	OC43	NNP
cord-256444-grw5s2pf	467	17	has	have	VBZ
cord-256444-grw5s2pf	467	18	the	the	DT
cord-256444-grw5s2pf	467	19	5a	5a	CD
cord-256444-grw5s2pf	467	20	ORF	ORF	NNP
cord-256444-grw5s2pf	467	21	but	but	CC
cord-256444-grw5s2pf	467	22	is	be	VBZ
cord-256444-grw5s2pf	467	23	unable	unable	JJ
cord-256444-grw5s2pf	467	24	to	to	TO
cord-256444-grw5s2pf	467	25	produce	produce	VB
cord-256444-grw5s2pf	467	26	a	a	DT
cord-256444-grw5s2pf	467	27	corresponding	correspond	VBG
cord-256444-grw5s2pf	467	28	mRNA	mrna	NN
cord-256444-grw5s2pf	467	29	(	(	-LRB-
cord-256444-grw5s2pf	467	30	Mounir	Mounir	NNP
cord-256444-grw5s2pf	467	31	and	and	CC
cord-256444-grw5s2pf	467	32	Talbot	Talbot	NNP
cord-256444-grw5s2pf	467	33	,	,	,
cord-256444-grw5s2pf	467	34	1993	1993	CD
cord-256444-grw5s2pf	467	35	)	)	-RRB-
cord-256444-grw5s2pf	467	36	.	.	.
cord-256444-grw5s2pf	468	1	In	in	IN
cord-256444-grw5s2pf	468	2	summary	summary	NN
cord-256444-grw5s2pf	468	3	,	,	,
cord-256444-grw5s2pf	468	4	there	there	EX
cord-256444-grw5s2pf	468	5	is	be	VBZ
cord-256444-grw5s2pf	468	6	great	great	JJ
cord-256444-grw5s2pf	468	7	heterogeneity	heterogeneity	NN
cord-256444-grw5s2pf	468	8	with	with	IN
cord-256444-grw5s2pf	468	9	respect	respect	NN
cord-256444-grw5s2pf	468	10	to	to	IN
cord-256444-grw5s2pf	468	11	the	the	DT
cord-256444-grw5s2pf	468	12	number	number	NN
cord-256444-grw5s2pf	468	13	,	,	,
cord-256444-grw5s2pf	468	14	size	size	NN
cord-256444-grw5s2pf	468	15	,	,	,
cord-256444-grw5s2pf	468	16	and	and	CC
cord-256444-grw5s2pf	468	17	mechanism	mechanism	NN
cord-256444-grw5s2pf	468	18	of	of	IN
cord-256444-grw5s2pf	468	19	expression	expression	NN
cord-256444-grw5s2pf	468	20	of	of	IN
cord-256444-grw5s2pf	468	21	ORFs	orfs	NN
cord-256444-grw5s2pf	468	22	between	between	IN
cord-256444-grw5s2pf	468	23	the	the	DT
cord-256444-grw5s2pf	468	24	S	s	NN
cord-256444-grw5s2pf	468	25	and	and	CC
cord-256444-grw5s2pf	468	26	E	e	NN
cord-256444-grw5s2pf	468	27	genes	gene	NNS
cord-256444-grw5s2pf	468	28	.	.	.
cord-256444-grw5s2pf	469	1	These	these	DT
cord-256444-grw5s2pf	469	2	ns	ns	IN
cord-256444-grw5s2pf	469	3	proteins	protein	NNS
cord-256444-grw5s2pf	469	4	probably	probably	RB
cord-256444-grw5s2pf	469	5	are	be	VBP
cord-256444-grw5s2pf	469	6	not	not	RB
cord-256444-grw5s2pf	469	7	required	require	VBN
cord-256444-grw5s2pf	469	8	for	for	IN
cord-256444-grw5s2pf	469	9	viral	viral	JJ
cord-256444-grw5s2pf	469	10	replication	replication	NN
cord-256444-grw5s2pf	469	11	.	.	.
cord-256444-grw5s2pf	470	1	The	the	DT
cord-256444-grw5s2pf	470	2	lack	lack	NN
cord-256444-grw5s2pf	470	3	of	of	IN
cord-256444-grw5s2pf	470	4	necessary	necessary	JJ
cord-256444-grw5s2pf	470	5	function	function	NN
cord-256444-grw5s2pf	470	6	may	may	MD
cord-256444-grw5s2pf	470	7	account	account	VB
cord-256444-grw5s2pf	470	8	for	for	IN
cord-256444-grw5s2pf	470	9	the	the	DT
cord-256444-grw5s2pf	470	10	heterogeneity	heterogeneity	NN
cord-256444-grw5s2pf	470	11	which	which	WDT
cord-256444-grw5s2pf	470	12	arose	arise	VBD
cord-256444-grw5s2pf	470	13	during	during	IN
cord-256444-grw5s2pf	470	14	evolution	evolution	NN
cord-256444-grw5s2pf	470	15	.	.	.
cord-256444-grw5s2pf	471	1	IBV	IBV	NNP
cord-256444-grw5s2pf	471	2	is	be	VBZ
cord-256444-grw5s2pf	471	3	unique	unique	JJ
cord-256444-grw5s2pf	471	4	in	in	IN
cord-256444-grw5s2pf	471	5	that	that	IN
cord-256444-grw5s2pf	471	6	it	-PRON-	PRP
cord-256444-grw5s2pf	471	7	has	have	VBZ
cord-256444-grw5s2pf	471	8	two	two	CD
cord-256444-grw5s2pf	471	9	ORFs	ORFs	NNP
cord-256444-grw5s2pf	471	10	(	(	-LRB-
cord-256444-grw5s2pf	471	11	5a	5a	NN
cord-256444-grw5s2pf	471	12	and	and	CC
cord-256444-grw5s2pf	471	13	5b	5b	CD
cord-256444-grw5s2pf	471	14	)	)	-RRB-
cord-256444-grw5s2pf	471	15	,	,	,
cord-256444-grw5s2pf	471	16	which	which	WDT
cord-256444-grw5s2pf	471	17	encode	encode	VBP
cord-256444-grw5s2pf	471	18	proteins	protein	NNS
cord-256444-grw5s2pf	471	19	of	of	IN
cord-256444-grw5s2pf	471	20	7.4	7.4	CD
cord-256444-grw5s2pf	471	21	and	and	CC
cord-256444-grw5s2pf	471	22	9.5	9.5	CD
cord-256444-grw5s2pf	471	23	kDa	kDa	NNS
cord-256444-grw5s2pf	471	24	,	,	,
cord-256444-grw5s2pf	471	25	respectively	respectively	RB
cord-256444-grw5s2pf	471	26	.	.	.
cord-256444-grw5s2pf	472	1	These	these	DT
cord-256444-grw5s2pf	472	2	proteins	protein	NNS
cord-256444-grw5s2pf	472	3	have	have	VBP
cord-256444-grw5s2pf	472	4	been	be	VBN
cord-256444-grw5s2pf	472	5	detected	detect	VBN
cord-256444-grw5s2pf	472	6	in	in	IN
cord-256444-grw5s2pf	472	7	very	very	RB
cord-256444-grw5s2pf	472	8	small	small	JJ
cord-256444-grw5s2pf	472	9	amounts	amount	NNS
cord-256444-grw5s2pf	472	10	in	in	IN
cord-256444-grw5s2pf	472	11	virus	virus	NN
cord-256444-grw5s2pf	472	12	-	-	HYPH
cord-256444-grw5s2pf	472	13	infected	infect	VBN
cord-256444-grw5s2pf	472	14	cells	cell	NNS
cord-256444-grw5s2pf	472	15	(	(	-LRB-
cord-256444-grw5s2pf	472	16	Liu	Liu	NNP
cord-256444-grw5s2pf	472	17	and	and	CC
cord-256444-grw5s2pf	472	18	Inglis	Inglis	NNP
cord-256444-grw5s2pf	472	19	,	,	,
cord-256444-grw5s2pf	472	20	1992a	1992a	CD
cord-256444-grw5s2pf	472	21	)	)	-RRB-
cord-256444-grw5s2pf	472	22	.	.	.
cord-256444-grw5s2pf	473	1	The	the	DT
cord-256444-grw5s2pf	473	2	function	function	NN
cord-256444-grw5s2pf	473	3	of	of	IN
cord-256444-grw5s2pf	473	4	these	these	DT
cord-256444-grw5s2pf	473	5	ORFs	orf	NNS
cord-256444-grw5s2pf	473	6	is	be	VBZ
cord-256444-grw5s2pf	473	7	not	not	RB
cord-256444-grw5s2pf	473	8	clear	clear	JJ
cord-256444-grw5s2pf	473	9	.	.	.
cord-256444-grw5s2pf	474	1	TGEV	TGEV	NNP
cord-256444-grw5s2pf	474	2	has	have	VBZ
cord-256444-grw5s2pf	474	3	an	an	DT
cord-256444-grw5s2pf	474	4	additional	additional	JJ
cord-256444-grw5s2pf	474	5	gene	gene	NN
cord-256444-grw5s2pf	474	6	7	7	CD
cord-256444-grw5s2pf	474	7	,	,	,
cord-256444-grw5s2pf	474	8	which	which	WDT
cord-256444-grw5s2pf	474	9	encodes	encode	VBZ
cord-256444-grw5s2pf	474	10	a	a	DT
cord-256444-grw5s2pf	474	11	9.1-kDa	9.1-kda	CD
cord-256444-grw5s2pf	474	12	protein	protein	NN
cord-256444-grw5s2pf	474	13	(	(	-LRB-
cord-256444-grw5s2pf	474	14	Garwes	Garwes	NNP
cord-256444-grw5s2pf	474	15	et	et	FW
cord-256444-grw5s2pf	474	16	al	al	NNP
cord-256444-grw5s2pf	474	17	.	.	NNP
cord-256444-grw5s2pf	474	18	,	,	,
cord-256444-grw5s2pf	474	19	1989	1989	CD
cord-256444-grw5s2pf	474	20	;	;	:
cord-256444-grw5s2pf	474	21	Tung	Tung	NNP
cord-256444-grw5s2pf	474	22	et	et	NNP
cord-256444-grw5s2pf	474	23	al	al	NNP
cord-256444-grw5s2pf	474	24	.	.	NNP
cord-256444-grw5s2pf	474	25	,	,	,
cord-256444-grw5s2pf	474	26	1992	1992	CD
cord-256444-grw5s2pf	474	27	)	)	-RRB-
cord-256444-grw5s2pf	474	28	,	,	,
cord-256444-grw5s2pf	474	29	in	in	IN
cord-256444-grw5s2pf	474	30	the	the	DT
cord-256444-grw5s2pf	474	31	region	region	NN
cord-256444-grw5s2pf	474	32	corresponding	correspond	VBG
cord-256444-grw5s2pf	474	33	to	to	IN
cord-256444-grw5s2pf	474	34	the	the	DT
cord-256444-grw5s2pf	474	35	3	3	CD
cord-256444-grw5s2pf	474	36	'	'	NN
cord-256444-grw5s2pf	474	37	end	end	JJ
cord-256444-grw5s2pf	474	38	untranslated	untranslated	JJ
cord-256444-grw5s2pf	474	39	region	region	NN
cord-256444-grw5s2pf	474	40	of	of	IN
cord-256444-grw5s2pf	474	41	other	other	JJ
cord-256444-grw5s2pf	474	42	viruses	virus	NNS
cord-256444-grw5s2pf	475	1	(	(	-LRB-
cord-256444-grw5s2pf	475	2	Fig	Fig	NNP
cord-256444-grw5s2pf	475	3	.	.	NNP
cord-256444-grw5s2pf	475	4	5	5	CD
cord-256444-grw5s2pf	475	5	)	)	-RRB-
cord-256444-grw5s2pf	475	6	.	.	.
cord-256444-grw5s2pf	476	1	This	this	DT
cord-256444-grw5s2pf	476	2	protein	protein	NN
cord-256444-grw5s2pf	476	3	is	be	VBZ
cord-256444-grw5s2pf	476	4	hydrophobic	hydrophobic	JJ
cord-256444-grw5s2pf	476	5	and	and	CC
cord-256444-grw5s2pf	476	6	is	be	VBZ
cord-256444-grw5s2pf	476	7	associated	associate	VBN
cord-256444-grw5s2pf	476	8	with	with	IN
cord-256444-grw5s2pf	476	9	the	the	DT
cord-256444-grw5s2pf	476	10	endoplasmic	endoplasmic	NN
cord-256444-grw5s2pf	476	11	reticulum	reticulum	NN
cord-256444-grw5s2pf	476	12	and	and	CC
cord-256444-grw5s2pf	476	13	cell	cell	NN
cord-256444-grw5s2pf	476	14	surface	surface	NN
cord-256444-grw5s2pf	476	15	membranes	membrane	NNS
cord-256444-grw5s2pf	476	16	(	(	-LRB-
cord-256444-grw5s2pf	476	17	Tung	Tung	NNP
cord-256444-grw5s2pf	476	18	et	et	FW
cord-256444-grw5s2pf	476	19	al	al	NNP
cord-256444-grw5s2pf	476	20	.	.	NNP
cord-256444-grw5s2pf	476	21	,	,	,
cord-256444-grw5s2pf	476	22	1992	1992	CD
cord-256444-grw5s2pf	476	23	)	)	-RRB-
cord-256444-grw5s2pf	476	24	,	,	,
cord-256444-grw5s2pf	476	25	but	but	CC
cord-256444-grw5s2pf	476	26	its	-PRON-	PRP$
cord-256444-grw5s2pf	476	27	nuclear	nuclear	JJ
cord-256444-grw5s2pf	476	28	localization	localization	NN
cord-256444-grw5s2pf	476	29	has	have	VBZ
cord-256444-grw5s2pf	476	30	also	also	RB
cord-256444-grw5s2pf	476	31	been	be	VBN
cord-256444-grw5s2pf	476	32	reported	report	VBN
cord-256444-grw5s2pf	477	1	(	(	-LRB-
cord-256444-grw5s2pf	477	2	Garwes	Garwes	NNP
cord-256444-grw5s2pf	477	3	et	et	FW
cord-256444-grw5s2pf	477	4	al	al	NNP
cord-256444-grw5s2pf	477	5	.	.	NNP
cord-256444-grw5s2pf	477	6	,	,	,
cord-256444-grw5s2pf	477	7	1989	1989	CD
cord-256444-grw5s2pf	477	8	)	)	-RRB-
cord-256444-grw5s2pf	477	9	.	.	.
cord-256444-grw5s2pf	478	1	FCVs	fcv	NNS
cord-256444-grw5s2pf	478	2	and	and	CC
cord-256444-grw5s2pf	478	3	CCV	CCV	NNP
cord-256444-grw5s2pf	478	4	have	have	VBP
cord-256444-grw5s2pf	478	5	two	two	CD
cord-256444-grw5s2pf	478	6	ORFs	orf	NNS
cord-256444-grw5s2pf	478	7	in	in	IN
cord-256444-grw5s2pf	478	8	the	the	DT
cord-256444-grw5s2pf	478	9	same	same	JJ
cord-256444-grw5s2pf	478	10	region	region	NN
cord-256444-grw5s2pf	478	11	,	,	,
cord-256444-grw5s2pf	478	12	the	the	DT
cord-256444-grw5s2pf	478	13	first	first	JJ
cord-256444-grw5s2pf	478	14	being	be	VBG
cord-256444-grw5s2pf	478	15	analogous	analogous	JJ
cord-256444-grw5s2pf	478	16	to	to	IN
cord-256444-grw5s2pf	478	17	the	the	DT
cord-256444-grw5s2pf	478	18	single	single	JJ
cord-256444-grw5s2pf	478	19	ORF	ORF	NNP
cord-256444-grw5s2pf	478	20	of	of	IN
cord-256444-grw5s2pf	478	21	TGEV	TGEV	NNP
cord-256444-grw5s2pf	478	22	.	.	.
cord-256444-grw5s2pf	479	1	The	the	DT
cord-256444-grw5s2pf	479	2	second	second	JJ
cord-256444-grw5s2pf	479	3	(	(	-LRB-
cord-256444-grw5s2pf	479	4	7b	7b	NN
cord-256444-grw5s2pf	479	5	)	)	-RRB-
cord-256444-grw5s2pf	479	6	ORF	ORF	NNP
cord-256444-grw5s2pf	479	7	encodes	encode	VBZ
cord-256444-grw5s2pf	479	8	a	a	DT
cord-256444-grw5s2pf	479	9	14-kDa	14-kda	CD
cord-256444-grw5s2pf	479	10	soluble	soluble	JJ
cord-256444-grw5s2pf	479	11	protein	protein	NN
cord-256444-grw5s2pf	479	12	containing	contain	VBG
cord-256444-grw5s2pf	479	13	the	the	DT
cord-256444-grw5s2pf	479	14	sequence	sequence	NN
cord-256444-grw5s2pf	479	15	KTEL	KTEL	NNP
cord-256444-grw5s2pf	479	16	(	(	-LRB-
cord-256444-grw5s2pf	479	17	Vennema	Vennema	NNP
cord-256444-grw5s2pf	479	18	et	et	FW
cord-256444-grw5s2pf	479	19	al	al	NNP
cord-256444-grw5s2pf	479	20	.	.	NNP
cord-256444-grw5s2pf	479	21	,	,	,
cord-256444-grw5s2pf	479	22	19921	19921	CD
cord-256444-grw5s2pf	479	23	,	,	,
cord-256444-grw5s2pf	479	24	which	which	WDT
cord-256444-grw5s2pf	479	25	is	be	VBZ
cord-256444-grw5s2pf	479	26	similar	similar	JJ
cord-256444-grw5s2pf	479	27	to	to	IN
cord-256444-grw5s2pf	479	28	the	the	DT
cord-256444-grw5s2pf	479	29	endoplasmic	endoplasmic	NN
cord-256444-grw5s2pf	479	30	reticulum	reticulum	NN
cord-256444-grw5s2pf	479	31	retention	retention	NN
cord-256444-grw5s2pf	479	32	signal	signal	NN
cord-256444-grw5s2pf	479	33	,	,	,
cord-256444-grw5s2pf	479	34	KDEL	KDEL	NNP
cord-256444-grw5s2pf	479	35	.	.	.
cord-256444-grw5s2pf	480	1	The	the	DT
cord-256444-grw5s2pf	480	2	protein	protein	NN
cord-256444-grw5s2pf	480	3	is	be	VBZ
cord-256444-grw5s2pf	480	4	partially	partially	RB
cord-256444-grw5s2pf	480	5	retained	retain	VBN
cord-256444-grw5s2pf	480	6	in	in	IN
cord-256444-grw5s2pf	480	7	the	the	DT
cord-256444-grw5s2pf	480	8	endoplasmic	endoplasmic	NN
cord-256444-grw5s2pf	480	9	reticulum	reticulum	NN
cord-256444-grw5s2pf	480	10	but	but	CC
cord-256444-grw5s2pf	480	11	is	be	VBZ
cord-256444-grw5s2pf	480	12	also	also	RB
cord-256444-grw5s2pf	480	13	slowly	slowly	RB
cord-256444-grw5s2pf	480	14	secreted	secrete	VBN
cord-256444-grw5s2pf	480	15	out	out	IN
cord-256444-grw5s2pf	480	16	of	of	IN
cord-256444-grw5s2pf	480	17	the	the	DT
cord-256444-grw5s2pf	480	18	cells	cell	NNS
cord-256444-grw5s2pf	480	19	.	.	.
cord-256444-grw5s2pf	481	1	The	the	DT
cord-256444-grw5s2pf	481	2	functions	function	NNS
cord-256444-grw5s2pf	481	3	of	of	IN
cord-256444-grw5s2pf	481	4	these	these	DT
cord-256444-grw5s2pf	481	5	proteins	protein	NNS
cord-256444-grw5s2pf	481	6	are	be	VBP
cord-256444-grw5s2pf	481	7	not	not	RB
cord-256444-grw5s2pf	481	8	known	know	VBN
cord-256444-grw5s2pf	481	9	.	.	.
cord-256444-grw5s2pf	482	1	Coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	482	2	have	have	VBP
cord-256444-grw5s2pf	482	3	relatively	relatively	RB
cord-256444-grw5s2pf	482	4	restricted	restrict	VBN
cord-256444-grw5s2pf	482	5	host	host	NN
cord-256444-grw5s2pf	482	6	ranges	range	NNS
cord-256444-grw5s2pf	482	7	,	,	,
cord-256444-grw5s2pf	482	8	infecting	infect	VBG
cord-256444-grw5s2pf	482	9	only	only	RB
cord-256444-grw5s2pf	482	10	their	-PRON-	PRP$
cord-256444-grw5s2pf	482	11	natural	natural	JJ
cord-256444-grw5s2pf	482	12	hosts	host	NNS
cord-256444-grw5s2pf	482	13	and	and	CC
cord-256444-grw5s2pf	482	14	closely	closely	RB
cord-256444-grw5s2pf	482	15	related	related	JJ
cord-256444-grw5s2pf	482	16	animal	animal	NN
cord-256444-grw5s2pf	482	17	species	specie	NNS
cord-256444-grw5s2pf	482	18	.	.	.
cord-256444-grw5s2pf	483	1	Occasionally	occasionally	RB
cord-256444-grw5s2pf	483	2	,	,	,
cord-256444-grw5s2pf	483	3	cross	cross	JJ
cord-256444-grw5s2pf	483	4	-	-	JJ
cord-256444-grw5s2pf	483	5	species	species	JJ
cord-256444-grw5s2pf	483	6	infection	infection	NN
cord-256444-grw5s2pf	483	7	of	of	IN
cord-256444-grw5s2pf	483	8	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	483	9	occurs	occur	VBZ
cord-256444-grw5s2pf	483	10	,	,	,
cord-256444-grw5s2pf	483	11	such	such	JJ
cord-256444-grw5s2pf	483	12	as	as	IN
cord-256444-grw5s2pf	483	13	the	the	DT
cord-256444-grw5s2pf	483	14	experimental	experimental	JJ
cord-256444-grw5s2pf	483	15	infection	infection	NN
cord-256444-grw5s2pf	483	16	of	of	IN
cord-256444-grw5s2pf	483	17	monkey	monkey	NN
cord-256444-grw5s2pf	483	18	by	by	IN
cord-256444-grw5s2pf	483	19	MHV	MHV	NNP
cord-256444-grw5s2pf	483	20	,	,	,
cord-256444-grw5s2pf	483	21	which	which	WDT
cord-256444-grw5s2pf	483	22	causes	cause	VBZ
cord-256444-grw5s2pf	483	23	central	central	JJ
cord-256444-grw5s2pf	483	24	nervous	nervous	JJ
cord-256444-grw5s2pf	483	25	system	system	NN
cord-256444-grw5s2pf	483	26	demyelination	demyelination	NN
cord-256444-grw5s2pf	483	27	(	(	-LRB-
cord-256444-grw5s2pf	483	28	Murray	Murray	NNP
cord-256444-grw5s2pf	483	29	et	et	NNP
cord-256444-grw5s2pf	483	30	al	al	NNP
cord-256444-grw5s2pf	483	31	.	.	NNP
cord-256444-grw5s2pf	483	32	,	,	,
cord-256444-grw5s2pf	483	33	1992	1992	CD
cord-256444-grw5s2pf	483	34	;	;	:
cord-256444-grw5s2pf	483	35	Cabirac	Cabirac	NNP
cord-256444-grw5s2pf	483	36	et	et	NNP
cord-256444-grw5s2pf	483	37	al	al	NNP
cord-256444-grw5s2pf	483	38	.	.	NNP
cord-256444-grw5s2pf	483	39	,	,	,
cord-256444-grw5s2pf	483	40	1994	1994	CD
cord-256444-grw5s2pf	483	41	)	)	-RRB-
cord-256444-grw5s2pf	483	42	,	,	,
cord-256444-grw5s2pf	483	43	and	and	CC
cord-256444-grw5s2pf	483	44	the	the	DT
cord-256444-grw5s2pf	483	45	occasional	occasional	JJ
cord-256444-grw5s2pf	483	46	infection	infection	NN
cord-256444-grw5s2pf	483	47	of	of	IN
cord-256444-grw5s2pf	483	48	humans	human	NNS
cord-256444-grw5s2pf	483	49	by	by	IN
cord-256444-grw5s2pf	483	50	BCV	BCV	NNP
cord-256444-grw5s2pf	483	51	,	,	,
cord-256444-grw5s2pf	483	52	which	which	WDT
cord-256444-grw5s2pf	483	53	causes	cause	VBZ
cord-256444-grw5s2pf	483	54	diarrhea	diarrhea	NN
cord-256444-grw5s2pf	483	55	.	.	.
cord-256444-grw5s2pf	484	1	BCV	BCV	NNP
cord-256444-grw5s2pf	484	2	also	also	RB
cord-256444-grw5s2pf	484	3	infects	infect	VBZ
cord-256444-grw5s2pf	484	4	turkeys	turkey	NNS
cord-256444-grw5s2pf	484	5	and	and	CC
cord-256444-grw5s2pf	484	6	TGEV	TGEV	NNS
cord-256444-grw5s2pf	484	7	infects	infect	VBZ
cord-256444-grw5s2pf	484	8	dogs	dog	NNS
cord-256444-grw5s2pf	484	9	,	,	,
cord-256444-grw5s2pf	484	10	suggesting	suggest	VBG
cord-256444-grw5s2pf	484	11	some	some	DT
cord-256444-grw5s2pf	484	12	flexibility	flexibility	NN
cord-256444-grw5s2pf	484	13	in	in	IN
cord-256444-grw5s2pf	484	14	their	-PRON-	PRP$
cord-256444-grw5s2pf	484	15	host	host	NN
cord-256444-grw5s2pf	484	16	range	range	NN
cord-256444-grw5s2pf	484	17	.	.	.
cord-256444-grw5s2pf	485	1	The	the	DT
cord-256444-grw5s2pf	485	2	expansion	expansion	NN
cord-256444-grw5s2pf	485	3	of	of	IN
cord-256444-grw5s2pf	485	4	viral	viral	JJ
cord-256444-grw5s2pf	485	5	host	host	NN
cord-256444-grw5s2pf	485	6	range	range	NN
cord-256444-grw5s2pf	485	7	can	can	MD
cord-256444-grw5s2pf	485	8	be	be	VB
cord-256444-grw5s2pf	485	9	achieved	achieve	VBN
cord-256444-grw5s2pf	485	10	by	by	IN
cord-256444-grw5s2pf	485	11	passing	pass	VBG
cord-256444-grw5s2pf	485	12	the	the	DT
cord-256444-grw5s2pf	485	13	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	485	14	in	in	IN
cord-256444-grw5s2pf	485	15	a	a	DT
cord-256444-grw5s2pf	485	16	heterologous	heterologous	JJ
cord-256444-grw5s2pf	485	17	cell	cell	NN
cord-256444-grw5s2pf	485	18	line	line	NN
cord-256444-grw5s2pf	485	19	,	,	,
cord-256444-grw5s2pf	485	20	as	as	IN
cord-256444-grw5s2pf	485	21	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	485	22	by	by	IN
cord-256444-grw5s2pf	485	23	the	the	DT
cord-256444-grw5s2pf	485	24	emergence	emergence	NN
cord-256444-grw5s2pf	485	25	of	of	IN
cord-256444-grw5s2pf	485	26	an	an	DT
cord-256444-grw5s2pf	485	27	MHY	MHY	NNP
cord-256444-grw5s2pf	485	28	variant	variant	NN
cord-256444-grw5s2pf	485	29	with	with	IN
cord-256444-grw5s2pf	485	30	the	the	DT
cord-256444-grw5s2pf	485	31	ability	ability	NN
cord-256444-grw5s2pf	485	32	to	to	TO
cord-256444-grw5s2pf	485	33	infect	infect	VB
cord-256444-grw5s2pf	485	34	originally	originally	RB
cord-256444-grw5s2pf	485	35	nonpermissive	nonpermissive	JJ
cord-256444-grw5s2pf	485	36	cell	cell	NN
cord-256444-grw5s2pf	485	37	lines	line	NNS
cord-256444-grw5s2pf	485	38	,	,	,
cord-256444-grw5s2pf	485	39	such	such	JJ
cord-256444-grw5s2pf	485	40	as	as	IN
cord-256444-grw5s2pf	485	41	human	human	JJ
cord-256444-grw5s2pf	485	42	cells	cell	NNS
cord-256444-grw5s2pf	485	43	,	,	,
cord-256444-grw5s2pf	485	44	after	after	IN
cord-256444-grw5s2pf	485	45	serial	serial	JJ
cord-256444-grw5s2pf	485	46	passages	passage	NNS
cord-256444-grw5s2pf	486	1	(	(	-LRB-
cord-256444-grw5s2pf	486	2	Baric	Baric	NNP
cord-256444-grw5s2pf	486	3	et	et	NNP
cord-256444-grw5s2pf	486	4	al	al	NNP
cord-256444-grw5s2pf	486	5	.	.	NNP
cord-256444-grw5s2pf	486	6	,	,	,
cord-256444-grw5s2pf	486	7	1997	1997	CD
cord-256444-grw5s2pf	486	8	)	)	-RRB-
cord-256444-grw5s2pf	486	9	.	.	.
cord-256444-grw5s2pf	487	1	In	in	IN
cord-256444-grw5s2pf	487	2	animals	animal	NNS
cord-256444-grw5s2pf	487	3	,	,	,
cord-256444-grw5s2pf	487	4	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	487	5	have	have	VBP
cord-256444-grw5s2pf	487	6	restricted	restrict	VBN
cord-256444-grw5s2pf	487	7	tissue	tissue	NN
cord-256444-grw5s2pf	487	8	tropism	tropism	NN
cord-256444-grw5s2pf	487	9	;	;	:
cord-256444-grw5s2pf	487	10	for	for	IN
cord-256444-grw5s2pf	487	11	example	example	NN
cord-256444-grw5s2pf	487	12	,	,	,
cord-256444-grw5s2pf	487	13	most	most	JJS
cord-256444-grw5s2pf	487	14	HCV	HCV	NNP
cord-256444-grw5s2pf	487	15	strains	strain	NNS
cord-256444-grw5s2pf	487	16	cause	cause	VBP
cord-256444-grw5s2pf	487	17	only	only	RB
cord-256444-grw5s2pf	487	18	respiratory	respiratory	JJ
cord-256444-grw5s2pf	487	19	infections	infection	NNS
cord-256444-grw5s2pf	487	20	.	.	.
cord-256444-grw5s2pf	488	1	Different	different	JJ
cord-256444-grw5s2pf	488	2	strains	strain	NNS
cord-256444-grw5s2pf	488	3	of	of	IN
cord-256444-grw5s2pf	488	4	a	a	DT
cord-256444-grw5s2pf	488	5	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	488	6	may	may	MD
cord-256444-grw5s2pf	488	7	have	have	VB
cord-256444-grw5s2pf	488	8	distinct	distinct	JJ
cord-256444-grw5s2pf	488	9	tissue	tissue	NN
cord-256444-grw5s2pf	488	10	specificity	specificity	NN
cord-256444-grw5s2pf	488	11	;	;	:
cord-256444-grw5s2pf	488	12	for	for	IN
cord-256444-grw5s2pf	488	13	example	example	NN
cord-256444-grw5s2pf	488	14	,	,	,
cord-256444-grw5s2pf	488	15	TGEV	TGEV	NNP
cord-256444-grw5s2pf	488	16	infects	infect	VBZ
cord-256444-grw5s2pf	488	17	both	both	CC
cord-256444-grw5s2pf	488	18	the	the	DT
cord-256444-grw5s2pf	488	19	gastrointestinal	gastrointestinal	JJ
cord-256444-grw5s2pf	488	20	tract	tract	NN
cord-256444-grw5s2pf	488	21	,	,	,
cord-256444-grw5s2pf	488	22	causing	cause	VBG
cord-256444-grw5s2pf	488	23	fatal	fatal	JJ
cord-256444-grw5s2pf	488	24	diarrhea	diarrhea	NN
cord-256444-grw5s2pf	488	25	,	,	,
cord-256444-grw5s2pf	488	26	and	and	CC
cord-256444-grw5s2pf	488	27	respiratory	respiratory	JJ
cord-256444-grw5s2pf	488	28	tract	tract	NN
cord-256444-grw5s2pf	488	29	tissues	tissue	NNS
cord-256444-grw5s2pf	488	30	without	without	IN
cord-256444-grw5s2pf	488	31	causing	cause	VBG
cord-256444-grw5s2pf	488	32	primary	primary	JJ
cord-256444-grw5s2pf	488	33	respiratory	respiratory	JJ
cord-256444-grw5s2pf	488	34	symptoms	symptom	NNS
cord-256444-grw5s2pf	488	35	,	,	,
cord-256444-grw5s2pf	488	36	whereas	whereas	IN
cord-256444-grw5s2pf	488	37	PRCV	PRCV	NNP
cord-256444-grw5s2pf	488	38	,	,	,
cord-256444-grw5s2pf	488	39	which	which	WDT
cord-256444-grw5s2pf	488	40	is	be	VBZ
cord-256444-grw5s2pf	488	41	closely	closely	RB
cord-256444-grw5s2pf	488	42	related	related	JJ
cord-256444-grw5s2pf	488	43	to	to	IN
cord-256444-grw5s2pf	488	44	TGEV	TGEV	NNP
cord-256444-grw5s2pf	488	45	,	,	,
cord-256444-grw5s2pf	488	46	infects	infect	VBZ
cord-256444-grw5s2pf	488	47	the	the	DT
cord-256444-grw5s2pf	488	48	respiratory	respiratory	JJ
cord-256444-grw5s2pf	488	49	tract	tract	NN
cord-256444-grw5s2pf	488	50	of	of	IN
cord-256444-grw5s2pf	488	51	pigs	pig	NNS
cord-256444-grw5s2pf	488	52	but	but	CC
cord-256444-grw5s2pf	488	53	replicates	replicate	VBZ
cord-256444-grw5s2pf	488	54	poorly	poorly	RB
cord-256444-grw5s2pf	488	55	in	in	IN
cord-256444-grw5s2pf	488	56	the	the	DT
cord-256444-grw5s2pf	488	57	intestinal	intestinal	JJ
cord-256444-grw5s2pf	488	58	tract	tract	NN
cord-256444-grw5s2pf	488	59	(	(	-LRB-
cord-256444-grw5s2pf	488	60	Cox	Cox	NNP
cord-256444-grw5s2pf	488	61	et	et	NNP
cord-256444-grw5s2pf	488	62	al	al	NNP
cord-256444-grw5s2pf	488	63	.	.	NNP
cord-256444-grw5s2pf	488	64	,	,	,
cord-256444-grw5s2pf	488	65	1990	1990	CD
cord-256444-grw5s2pf	488	66	)	)	-RRB-
cord-256444-grw5s2pf	488	67	.	.	.
cord-256444-grw5s2pf	489	1	The	the	DT
cord-256444-grw5s2pf	489	2	species	specie	NNS
cord-256444-grw5s2pf	489	3	and	and	CC
cord-256444-grw5s2pf	489	4	tissue	tissue	NN
cord-256444-grw5s2pf	489	5	specificity	specificity	NN
cord-256444-grw5s2pf	489	6	of	of	IN
cord-256444-grw5s2pf	489	7	a	a	DT
cord-256444-grw5s2pf	489	8	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	489	9	infection	infection	NN
cord-256444-grw5s2pf	489	10	is	be	VBZ
cord-256444-grw5s2pf	489	11	a	a	DT
cord-256444-grw5s2pf	489	12	t	t	NN
cord-256444-grw5s2pf	489	13	least	least	RBS
cord-256444-grw5s2pf	489	14	partially	partially	RB
cord-256444-grw5s2pf	489	15	dictated	dictate	VBN
cord-256444-grw5s2pf	489	16	by	by	IN
cord-256444-grw5s2pf	489	17	the	the	DT
cord-256444-grw5s2pf	489	18	nature	nature	NN
cord-256444-grw5s2pf	489	19	and	and	CC
cord-256444-grw5s2pf	489	20	distribution	distribution	NN
cord-256444-grw5s2pf	489	21	of	of	IN
cord-256444-grw5s2pf	489	22	cellular	cellular	JJ
cord-256444-grw5s2pf	489	23	receptors	receptor	NNS
cord-256444-grw5s2pf	489	24	and	and	CC
cord-256444-grw5s2pf	489	25	other	other	JJ
cord-256444-grw5s2pf	489	26	related	related	JJ
cord-256444-grw5s2pf	489	27	molecules	molecule	NNS
cord-256444-grw5s2pf	489	28	that	that	WDT
cord-256444-grw5s2pf	489	29	regulate	regulate	VBP
cord-256444-grw5s2pf	489	30	virus	virus	NN
cord-256444-grw5s2pf	489	31	entry	entry	NN
cord-256444-grw5s2pf	489	32	,	,	,
cord-256444-grw5s2pf	489	33	as	as	IN
cord-256444-grw5s2pf	489	34	evidenced	evidence	VBN
cord-256444-grw5s2pf	489	35	by	by	IN
cord-256444-grw5s2pf	489	36	the	the	DT
cord-256444-grw5s2pf	489	37	viral	viral	JJ
cord-256444-grw5s2pf	489	38	replication	replication	NN
cord-256444-grw5s2pf	489	39	that	that	WDT
cord-256444-grw5s2pf	489	40	results	result	VBZ
cord-256444-grw5s2pf	489	41	when	when	WRB
cord-256444-grw5s2pf	489	42	viral	viral	JJ
cord-256444-grw5s2pf	489	43	RNA	RNA	NNP
cord-256444-grw5s2pf	489	44	is	be	VBZ
cord-256444-grw5s2pf	489	45	directly	directly	RB
cord-256444-grw5s2pf	489	46	introduced	introduce	VBN
cord-256444-grw5s2pf	489	47	into	into	IN
cord-256444-grw5s2pf	489	48	cell	cell	NN
cord-256444-grw5s2pf	489	49	types	type	NNS
cord-256444-grw5s2pf	489	50	of	of	IN
cord-256444-grw5s2pf	489	51	other	other	JJ
cord-256444-grw5s2pf	489	52	animal	animal	NN
cord-256444-grw5s2pf	489	53	species	specie	NNS
cord-256444-grw5s2pf	489	54	.	.	.
cord-256444-grw5s2pf	490	1	Thus	thus	RB
cord-256444-grw5s2pf	490	2	,	,	,
cord-256444-grw5s2pf	490	3	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	490	4	have	have	VBP
cord-256444-grw5s2pf	490	5	the	the	DT
cord-256444-grw5s2pf	490	6	potential	potential	NN
cord-256444-grw5s2pf	490	7	to	to	TO
cord-256444-grw5s2pf	490	8	replicate	replicate	VB
cord-256444-grw5s2pf	490	9	in	in	IN
cord-256444-grw5s2pf	490	10	many	many	JJ
cord-256444-grw5s2pf	490	11	cell	cell	NN
cord-256444-grw5s2pf	490	12	types	type	NNS
cord-256444-grw5s2pf	490	13	.	.	.
cord-256444-grw5s2pf	491	1	The	the	DT
cord-256444-grw5s2pf	491	2	complete	complete	JJ
cord-256444-grw5s2pf	491	3	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	491	4	replication	replication	NN
cord-256444-grw5s2pf	491	5	cycle	cycle	NN
cord-256444-grw5s2pf	491	6	takes	take	VBZ
cord-256444-grw5s2pf	491	7	place	place	NN
cord-256444-grw5s2pf	491	8	in	in	IN
cord-256444-grw5s2pf	491	9	the	the	DT
cord-256444-grw5s2pf	491	10	cytoplasm	cytoplasm	NN
cord-256444-grw5s2pf	491	11	.	.	.
cord-256444-grw5s2pf	492	1	It	-PRON-	PRP
cord-256444-grw5s2pf	492	2	has	have	VBZ
cord-256444-grw5s2pf	492	3	been	be	VBN
cord-256444-grw5s2pf	492	4	shown	show	VBN
cord-256444-grw5s2pf	492	5	that	that	IN
cord-256444-grw5s2pf	492	6	MHV	MHV	NNP
cord-256444-grw5s2pf	492	7	can	can	MD
cord-256444-grw5s2pf	492	8	replicate	replicate	VB
cord-256444-grw5s2pf	492	9	in	in	IN
cord-256444-grw5s2pf	492	10	enucleated	enucleated	JJ
cord-256444-grw5s2pf	492	11	cells	cell	NNS
cord-256444-grw5s2pf	492	12	and	and	CC
cord-256444-grw5s2pf	492	13	in	in	IN
cord-256444-grw5s2pf	492	14	the	the	DT
cord-256444-grw5s2pf	492	15	presence	presence	NN
cord-256444-grw5s2pf	492	16	of	of	IN
cord-256444-grw5s2pf	492	17	actinomycin	actinomycin	NNS
cord-256444-grw5s2pf	492	18	D	D	NNP
cord-256444-grw5s2pf	492	19	and	and	CC
cord-256444-grw5s2pf	492	20	a	a	DT
cord-256444-grw5s2pf	492	21	-	-	HYPH
cord-256444-grw5s2pf	492	22	amanitin	amanitin	NNP
cord-256444-grw5s2pf	492	23	,	,	,
cord-256444-grw5s2pf	492	24	suggesting	suggest	VBG
cord-256444-grw5s2pf	492	25	that	that	IN
cord-256444-grw5s2pf	492	26	nuclear	nuclear	JJ
cord-256444-grw5s2pf	492	27	functions	function	NNS
cord-256444-grw5s2pf	492	28	are	be	VBP
cord-256444-grw5s2pf	492	29	not	not	RB
cord-256444-grw5s2pf	492	30	required	require	VBN
cord-256444-grw5s2pf	492	31	for	for	IN
cord-256444-grw5s2pf	492	32	viral	viral	JJ
cord-256444-grw5s2pf	492	33	replication	replication	NN
cord-256444-grw5s2pf	492	34	Wilhelmsen	Wilhelmsen	NNP
cord-256444-grw5s2pf	492	35	et	et	NNP
cord-256444-grw5s2pf	492	36	al	al	NNP
cord-256444-grw5s2pf	492	37	.	.	NNP
cord-256444-grw5s2pf	492	38	,	,	,
cord-256444-grw5s2pf	492	39	1981	1981	CD
cord-256444-grw5s2pf	492	40	)	)	-RRB-
cord-256444-grw5s2pf	492	41	.	.	.
cord-256444-grw5s2pf	493	1	There	there	EX
cord-256444-grw5s2pf	493	2	are	be	VBP
cord-256444-grw5s2pf	493	3	,	,	,
cord-256444-grw5s2pf	493	4	however	however	RB
cord-256444-grw5s2pf	493	5	,	,	,
cord-256444-grw5s2pf	493	6	reports	report	NNS
cord-256444-grw5s2pf	493	7	of	of	IN
cord-256444-grw5s2pf	493	8	the	the	DT
cord-256444-grw5s2pf	493	9	inhibition	inhibition	NN
cord-256444-grw5s2pf	493	10	of	of	IN
cord-256444-grw5s2pf	493	11	replication	replication	NN
cord-256444-grw5s2pf	493	12	by	by	IN
cord-256444-grw5s2pf	493	13	actinomycin	actinomycin	NNS
cord-256444-grw5s2pf	493	14	D	D	NNP
cord-256444-grw5s2pf	493	15	of	of	IN
cord-256444-grw5s2pf	493	16	some	some	DT
cord-256444-grw5s2pf	493	17	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	493	18	,	,	,
cord-256444-grw5s2pf	493	19	including	include	VBG
cord-256444-grw5s2pf	493	20	feline	feline	JJ
cord-256444-grw5s2pf	493	21	enteric	enteric	JJ
cord-256444-grw5s2pf	493	22	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	493	23	(	(	-LRB-
cord-256444-grw5s2pf	493	24	Lewis	Lewis	NNP
cord-256444-grw5s2pf	493	25	et	et	NNP
cord-256444-grw5s2pf	493	26	al	al	NNP
cord-256444-grw5s2pf	493	27	.	.	NNP
cord-256444-grw5s2pf	493	28	,	,	,
cord-256444-grw5s2pf	493	29	19931	19931	CD
cord-256444-grw5s2pf	493	30	,	,	,
cord-256444-grw5s2pf	493	31	IBV	IBV	NNP
cord-256444-grw5s2pf	493	32	(	(	-LRB-
cord-256444-grw5s2pf	493	33	Evans	Evans	NNP
cord-256444-grw5s2pf	493	34	and	and	CC
cord-256444-grw5s2pf	493	35	Simpson	Simpson	NNP
cord-256444-grw5s2pf	493	36	,	,	,
cord-256444-grw5s2pf	493	37	19801	19801	CD
cord-256444-grw5s2pf	493	38	,	,	,
cord-256444-grw5s2pf	493	39	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	493	40	(	(	-LRB-
cord-256444-grw5s2pf	493	41	Kennedy	Kennedy	NNP
cord-256444-grw5s2pf	493	42	and	and	CC
cord-256444-grw5s2pf	493	43	Johnson	Johnson	NNP
cord-256444-grw5s2pf	493	44	-	-	HYPH
cord-256444-grw5s2pf	493	45	Lussenberg	Lussenberg	NNP
cord-256444-grw5s2pf	493	46	,	,	,
cord-256444-grw5s2pf	493	47	19781	19781	CD
cord-256444-grw5s2pf	493	48	,	,	,
cord-256444-grw5s2pf	493	49	and	and	CC
cord-256444-grw5s2pf	493	50	MHV	mhv	NN
cord-256444-grw5s2pf	493	51	in	in	IN
cord-256444-grw5s2pf	493	52	some	some	DT
cord-256444-grw5s2pf	493	53	cell	cell	NN
cord-256444-grw5s2pf	493	54	lines	line	NNS
cord-256444-grw5s2pf	493	55	(	(	-LRB-
cord-256444-grw5s2pf	493	56	Dupuy	Dupuy	NNP
cord-256444-grw5s2pf	493	57	and	and	CC
cord-256444-grw5s2pf	493	58	Lamontagne	Lamontagne	NNP
cord-256444-grw5s2pf	493	59	,	,	,
cord-256444-grw5s2pf	493	60	1987	1987	CD
cord-256444-grw5s2pf	493	61	)	)	-RRB-
cord-256444-grw5s2pf	493	62	.	.	.
cord-256444-grw5s2pf	494	1	Thus	thus	RB
cord-256444-grw5s2pf	494	2	,	,	,
cord-256444-grw5s2pf	494	3	nuclear	nuclear	JJ
cord-256444-grw5s2pf	494	4	functions	function	NNS
cord-256444-grw5s2pf	494	5	may	may	MD
cord-256444-grw5s2pf	494	6	be	be	VB
cord-256444-grw5s2pf	494	7	required	require	VBN
cord-256444-grw5s2pf	494	8	for	for	IN
cord-256444-grw5s2pf	494	9	viral	viral	JJ
cord-256444-grw5s2pf	494	10	replication	replication	NN
cord-256444-grw5s2pf	494	11	under	under	IN
cord-256444-grw5s2pf	494	12	certain	certain	JJ
cord-256444-grw5s2pf	494	13	conditions	condition	NNS
cord-256444-grw5s2pf	494	14	.	.	.
cord-256444-grw5s2pf	495	1	This	this	DT
cord-256444-grw5s2pf	495	2	issue	issue	NN
cord-256444-grw5s2pf	495	3	has	have	VBZ
cord-256444-grw5s2pf	495	4	not	not	RB
cord-256444-grw5s2pf	495	5	been	be	VBN
cord-256444-grw5s2pf	495	6	resolved	resolve	VBN
cord-256444-grw5s2pf	495	7	.	.	.
cord-256444-grw5s2pf	496	1	The	the	DT
cord-256444-grw5s2pf	496	2	first	first	JJ
cord-256444-grw5s2pf	496	3	step	step	NN
cord-256444-grw5s2pf	496	4	in	in	IN
cord-256444-grw5s2pf	496	5	viral	viral	JJ
cord-256444-grw5s2pf	496	6	infection	infection	NN
cord-256444-grw5s2pf	496	7	is	be	VBZ
cord-256444-grw5s2pf	496	8	the	the	DT
cord-256444-grw5s2pf	496	9	binding	binding	NN
cord-256444-grw5s2pf	496	10	of	of	IN
cord-256444-grw5s2pf	496	11	the	the	DT
cord-256444-grw5s2pf	496	12	virus	virus	NN
cord-256444-grw5s2pf	496	13	to	to	TO
cord-256444-grw5s2pf	496	14	target	target	VB
cord-256444-grw5s2pf	496	15	cells	cell	NNS
cord-256444-grw5s2pf	496	16	.	.	.
cord-256444-grw5s2pf	497	1	Hemagglutination	hemagglutination	NN
cord-256444-grw5s2pf	497	2	and	and	CC
cord-256444-grw5s2pf	497	3	hemadsorption	hemadsorption	NN
cord-256444-grw5s2pf	497	4	have	have	VBP
cord-256444-grw5s2pf	497	5	been	be	VBN
cord-256444-grw5s2pf	497	6	used	use	VBN
cord-256444-grw5s2pf	497	7	as	as	IN
cord-256444-grw5s2pf	497	8	assays	assay	NNS
cord-256444-grw5s2pf	497	9	for	for	IN
cord-256444-grw5s2pf	497	10	studying	study	VBG
cord-256444-grw5s2pf	497	11	virus	virus	NN
cord-256444-grw5s2pf	497	12	-	-	HYPH
cord-256444-grw5s2pf	497	13	cell	cell	NN
cord-256444-grw5s2pf	497	14	interaction	interaction	NN
cord-256444-grw5s2pf	497	15	,	,	,
cord-256444-grw5s2pf	497	16	although	although	IN
cord-256444-grw5s2pf	497	17	the	the	DT
cord-256444-grw5s2pf	497	18	erythrocyte	erythrocyte	NN
cord-256444-grw5s2pf	497	19	itself	-PRON-	PRP
cord-256444-grw5s2pf	497	20	is	be	VBZ
cord-256444-grw5s2pf	497	21	not	not	RB
cord-256444-grw5s2pf	497	22	a	a	DT
cord-256444-grw5s2pf	497	23	target	target	NN
cord-256444-grw5s2pf	497	24	cell	cell	NN
cord-256444-grw5s2pf	497	25	for	for	IN
cord-256444-grw5s2pf	497	26	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	497	27	infection	infection	NN
cord-256444-grw5s2pf	497	28	.	.	.
cord-256444-grw5s2pf	498	1	Several	several	JJ
cord-256444-grw5s2pf	498	2	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	498	3	,	,	,
cord-256444-grw5s2pf	498	4	including	include	VBG
cord-256444-grw5s2pf	498	5	HEV	HEV	NNP
cord-256444-grw5s2pf	498	6	,	,	,
cord-256444-grw5s2pf	498	7	IBV	IBV	NNP
cord-256444-grw5s2pf	498	8	,	,	,
cord-256444-grw5s2pf	498	9	BCV	BCV	NNP
cord-256444-grw5s2pf	498	10	,	,	,
cord-256444-grw5s2pf	498	11	and	and	CC
cord-256444-grw5s2pf	498	12	some	some	DT
cord-256444-grw5s2pf	498	13	strains	strain	NNS
cord-256444-grw5s2pf	498	14	of	of	IN
cord-256444-grw5s2pf	498	15	MHV	MHV	NNP
cord-256444-grw5s2pf	498	16	and	and	CC
cord-256444-grw5s2pf	498	17	HCV	HCV	NNP
cord-256444-grw5s2pf	498	18	,	,	,
cord-256444-grw5s2pf	498	19	can	can	MD
cord-256444-grw5s2pf	498	20	cause	cause	VB
cord-256444-grw5s2pf	498	21	hemagglutination	hemagglutination	NN
cord-256444-grw5s2pf	499	1	(	(	-LRB-
cord-256444-grw5s2pf	499	2	Sugiyama	Sugiyama	NNP
cord-256444-grw5s2pf	499	3	and	and	CC
cord-256444-grw5s2pf	499	4	Amano	Amano	NNP
cord-256444-grw5s2pf	499	5	,	,	,
cord-256444-grw5s2pf	499	6	1980	1980	CD
cord-256444-grw5s2pf	499	7	;	;	:
cord-256444-grw5s2pf	499	8	Schultze	Schultze	NNP
cord-256444-grw5s2pf	499	9	et	et	NNP
cord-256444-grw5s2pf	499	10	al	al	NNP
cord-256444-grw5s2pf	499	11	.	.	NNP
cord-256444-grw5s2pf	499	12	,	,	,
cord-256444-grw5s2pf	499	13	1990	1990	CD
cord-256444-grw5s2pf	499	14	;	;	:
cord-256444-grw5s2pf	500	1	Zhang	Zhang	NNP
cord-256444-grw5s2pf	500	2	et	et	NNP
cord-256444-grw5s2pf	500	3	al	al	NNP
cord-256444-grw5s2pf	500	4	.	.	NNP
cord-256444-grw5s2pf	500	5	,	,	,
cord-256444-grw5s2pf	500	6	1994a	1994a	CD
cord-256444-grw5s2pf	500	7	)	)	-RRB-
cord-256444-grw5s2pf	500	8	.	.	.
cord-256444-grw5s2pf	501	1	The	the	DT
cord-256444-grw5s2pf	501	2	binding	binding	JJ
cord-256444-grw5s2pf	501	3	residue	residue	NN
cord-256444-grw5s2pf	501	4	on	on	IN
cord-256444-grw5s2pf	501	5	the	the	DT
cord-256444-grw5s2pf	501	6	cell	cell	NN
cord-256444-grw5s2pf	501	7	surface	surface	NN
cord-256444-grw5s2pf	501	8	is	be	VBZ
cord-256444-grw5s2pf	501	9	a	a	DT
cord-256444-grw5s2pf	501	10	9-O	9-o	CD
cord-256444-grw5s2pf	501	11	-	-	HYPH
cord-256444-grw5s2pf	501	12	acetylated	acetylated	JJ
cord-256444-grw5s2pf	501	13	neuraminic	neuraminic	JJ
cord-256444-grw5s2pf	501	14	acid	acid	NN
cord-256444-grw5s2pf	501	15	of	of	IN
cord-256444-grw5s2pf	501	16	glycoproteins	glycoprotein	NNS
cord-256444-grw5s2pf	501	17	or	or	CC
cord-256444-grw5s2pf	501	18	glycolipids	glycolipid	NNS
cord-256444-grw5s2pf	502	1	(	(	-LRB-
cord-256444-grw5s2pf	502	2	Schultze	Schultze	NNP
cord-256444-grw5s2pf	502	3	et	et	NNP
cord-256444-grw5s2pf	502	4	al	al	NNP
cord-256444-grw5s2pf	502	5	.	.	.
cord-256444-grw5s2pf	503	1	,	,	,
cord-256444-grw5s2pf	503	2	19901	19901	CD
cord-256444-grw5s2pf	503	3	,	,	,
cord-256444-grw5s2pf	503	4	although	although	IN
cord-256444-grw5s2pf	503	5	different	different	JJ
cord-256444-grw5s2pf	503	6	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	503	7	may	may	MD
cord-256444-grw5s2pf	503	8	prefer	prefer	VB
cord-256444-grw5s2pf	503	9	different	different	JJ
cord-256444-grw5s2pf	503	10	structural	structural	JJ
cord-256444-grw5s2pf	503	11	isoforms	isoform	NNS
cord-256444-grw5s2pf	503	12	of	of	IN
cord-256444-grw5s2pf	503	13	9-O	9-o	CD
cord-256444-grw5s2pf	503	14	-	-	HYPH
cord-256444-grw5s2pf	503	15	acetylated	acetylated	JJ
cord-256444-grw5s2pf	503	16	neuraminic	neuraminic	JJ
cord-256444-grw5s2pf	503	17	acid	acid	NN
cord-256444-grw5s2pf	503	18	.	.	.
cord-256444-grw5s2pf	504	1	For	for	IN
cord-256444-grw5s2pf	504	2	BCV	BCV	NNP
cord-256444-grw5s2pf	504	3	,	,	,
cord-256444-grw5s2pf	504	4	the	the	DT
cord-256444-grw5s2pf	504	5	virus	virus	NN
cord-256444-grw5s2pf	504	6	binding	bind	VBG
cord-256444-grw5s2pf	504	7	to	to	IN
cord-256444-grw5s2pf	504	8	erythrocytes	erythrocyte	NNS
cord-256444-grw5s2pf	504	9	is	be	VBZ
cord-256444-grw5s2pf	504	10	mediated	mediate	VBN
cord-256444-grw5s2pf	504	11	through	through	IN
cord-256444-grw5s2pf	504	12	either	either	CC
cord-256444-grw5s2pf	504	13	the	the	DT
cord-256444-grw5s2pf	504	14	S	S	NNP
cord-256444-grw5s2pf	504	15	or	or	CC
cord-256444-grw5s2pf	504	16	HE	HE	NNP
cord-256444-grw5s2pf	504	17	protein	protein	NN
cord-256444-grw5s2pf	504	18	,	,	,
cord-256444-grw5s2pf	504	19	both	both	DT
cord-256444-grw5s2pf	504	20	of	of	IN
cord-256444-grw5s2pf	504	21	which	which	WDT
cord-256444-grw5s2pf	504	22	have	have	VBP
cord-256444-grw5s2pf	504	23	hemagglutinating	hemagglutinating	NN
cord-256444-grw5s2pf	504	24	activities	activity	NNS
cord-256444-grw5s2pf	504	25	,	,	,
cord-256444-grw5s2pf	504	26	the	the	DT
cord-256444-grw5s2pf	504	27	S	S	NNP
cord-256444-grw5s2pf	504	28	protein	protein	NN
cord-256444-grw5s2pf	504	29	having	have	VBG
cord-256444-grw5s2pf	504	30	the	the	DT
cord-256444-grw5s2pf	504	31	stronger	strong	JJR
cord-256444-grw5s2pf	504	32	activity	activity	NN
cord-256444-grw5s2pf	504	33	(	(	-LRB-
cord-256444-grw5s2pf	504	34	King	King	NNP
cord-256444-grw5s2pf	504	35	et	et	NNP
cord-256444-grw5s2pf	504	36	al	al	NNP
cord-256444-grw5s2pf	504	37	.	.	NNP
cord-256444-grw5s2pf	504	38	,	,	,
cord-256444-grw5s2pf	504	39	1985	1985	CD
cord-256444-grw5s2pf	504	40	;	;	:
cord-256444-grw5s2pf	505	1	Schultze	Schultze	NNP
cord-256444-grw5s2pf	505	2	et	et	NNP
cord-256444-grw5s2pf	505	3	al	al	NNP
cord-256444-grw5s2pf	505	4	.	.	NNP
cord-256444-grw5s2pf	505	5	,	,	,
cord-256444-grw5s2pf	505	6	1991a	1991a	CD
cord-256444-grw5s2pf	505	7	,	,	,
cord-256444-grw5s2pf	505	8	b	b	LS
cord-256444-grw5s2pf	505	9	)	)	-RRB-
cord-256444-grw5s2pf	505	10	.	.	.
cord-256444-grw5s2pf	506	1	The	the	DT
cord-256444-grw5s2pf	506	2	HE	HE	NNP
cord-256444-grw5s2pf	506	3	protein	protein	NN
cord-256444-grw5s2pf	506	4	of	of	IN
cord-256444-grw5s2pf	506	5	BCV	BCV	NNP
cord-256444-grw5s2pf	506	6	and	and	CC
cord-256444-grw5s2pf	506	7	HEV	HEV	NNP
cord-256444-grw5s2pf	506	8	also	also	RB
cord-256444-grw5s2pf	506	9	recognizes	recognize	VBZ
cord-256444-grw5s2pf	506	10	9-O	9-o	CD
cord-256444-grw5s2pf	506	11	-	-	HYPH
cord-256444-grw5s2pf	506	12	acetylated	acetylated	JJ
cord-256444-grw5s2pf	506	13	neuraminic	neuraminic	JJ
cord-256444-grw5s2pf	506	14	acid	acid	NN
cord-256444-grw5s2pf	506	15	,	,	,
cord-256444-grw5s2pf	506	16	and	and	CC
cord-256444-grw5s2pf	506	17	its	-PRON-	PRP$
cord-256444-grw5s2pf	506	18	esterase	esterase	NN
cord-256444-grw5s2pf	506	19	activity	activity	NN
cord-256444-grw5s2pf	506	20	is	be	VBZ
cord-256444-grw5s2pf	506	21	also	also	RB
cord-256444-grw5s2pf	506	22	specific	specific	JJ
cord-256444-grw5s2pf	506	23	for	for	IN
cord-256444-grw5s2pf	506	24	this	this	DT
cord-256444-grw5s2pf	506	25	molecule	molecule	NN
cord-256444-grw5s2pf	506	26	;	;	:
cord-256444-grw5s2pf	506	27	thus	thus	RB
cord-256444-grw5s2pf	506	28	,	,	,
cord-256444-grw5s2pf	506	29	HE	HE	NNP
cord-256444-grw5s2pf	506	30	protein	protein	NN
cord-256444-grw5s2pf	506	31	has	have	VBZ
cord-256444-grw5s2pf	506	32	both	both	DT
cord-256444-grw5s2pf	506	33	receptor	receptor	NN
cord-256444-grw5s2pf	506	34	-	-	HYPH
cord-256444-grw5s2pf	506	35	binding	bind	VBG
cord-256444-grw5s2pf	506	36	and	and	CC
cord-256444-grw5s2pf	506	37	receptor	receptor	NN
cord-256444-grw5s2pf	506	38	-	-	HYPH
cord-256444-grw5s2pf	506	39	destroying	destroy	VBG
cord-256444-grw5s2pf	506	40	activities	activity	NNS
cord-256444-grw5s2pf	506	41	(	(	-LRB-
cord-256444-grw5s2pf	506	42	Vlasak	Vlasak	NNP
cord-256444-grw5s2pf	506	43	et	et	NNP
cord-256444-grw5s2pf	506	44	al	al	NNP
cord-256444-grw5s2pf	506	45	.	.	NNP
cord-256444-grw5s2pf	506	46	,	,	,
cord-256444-grw5s2pf	506	47	1988a	1988a	CD
cord-256444-grw5s2pf	506	48	,	,	,
cord-256444-grw5s2pf	506	49	b	b	NN
cord-256444-grw5s2pf	506	50	;	;	:
cord-256444-grw5s2pf	507	1	Schultze	Schultze	NNP
cord-256444-grw5s2pf	507	2	et	et	NNP
cord-256444-grw5s2pf	507	3	al	al	NNP
cord-256444-grw5s2pf	507	4	.	.	NNP
cord-256444-grw5s2pf	507	5	,	,	,
cord-256444-grw5s2pf	507	6	1991b	1991b	CD
cord-256444-grw5s2pf	507	7	)	)	-RRB-
cord-256444-grw5s2pf	507	8	.	.	.
cord-256444-grw5s2pf	508	1	Expression	expression	NN
cord-256444-grw5s2pf	508	2	of	of	IN
cord-256444-grw5s2pf	508	3	the	the	DT
cord-256444-grw5s2pf	508	4	HE	HE	NNP
cord-256444-grw5s2pf	508	5	protein	protein	NN
cord-256444-grw5s2pf	508	6	of	of	IN
cord-256444-grw5s2pf	508	7	MHV	MHV	NNP
cord-256444-grw5s2pf	508	8	on	on	IN
cord-256444-grw5s2pf	508	9	the	the	DT
cord-256444-grw5s2pf	508	10	cell	cell	NN
cord-256444-grw5s2pf	508	11	surface	surface	NN
cord-256444-grw5s2pf	508	12	conferred	confer	VBD
cord-256444-grw5s2pf	508	13	a	a	DT
cord-256444-grw5s2pf	508	14	hemadsorption	hemadsorption	NN
cord-256444-grw5s2pf	508	15	activity	activity	NN
cord-256444-grw5s2pf	508	16	;	;	:
cord-256444-grw5s2pf	508	17	however	however	RB
cord-256444-grw5s2pf	508	18	,	,	,
cord-256444-grw5s2pf	508	19	even	even	RB
cord-256444-grw5s2pf	508	20	viruses	virus	NNS
cord-256444-grw5s2pf	508	21	that	that	WDT
cord-256444-grw5s2pf	508	22	lack	lack	VBP
cord-256444-grw5s2pf	508	23	HE	HE	NNP
cord-256444-grw5s2pf	508	24	protein	protein	NN
cord-256444-grw5s2pf	508	25	(	(	-LRB-
cord-256444-grw5s2pf	508	26	e.g.	e.g.	RB
cord-256444-grw5s2pf	508	27	,	,	,
cord-256444-grw5s2pf	508	28	IBV	IBV	NNP
cord-256444-grw5s2pf	508	29	)	)	-RRB-
cord-256444-grw5s2pf	508	30	can	can	MD
cord-256444-grw5s2pf	508	31	cause	cause	VB
cord-256444-grw5s2pf	508	32	hemagglutination	hemagglutination	NN
cord-256444-grw5s2pf	508	33	,	,	,
cord-256444-grw5s2pf	508	34	suggesting	suggest	VBG
cord-256444-grw5s2pf	508	35	the	the	DT
cord-256444-grw5s2pf	508	36	role	role	NN
cord-256444-grw5s2pf	508	37	of	of	IN
cord-256444-grw5s2pf	508	38	S	S	NNP
cord-256444-grw5s2pf	508	39	protein	protein	NN
cord-256444-grw5s2pf	508	40	in	in	IN
cord-256444-grw5s2pf	508	41	hemagglutination	hemagglutination	NN
cord-256444-grw5s2pf	508	42	.	.	.
cord-256444-grw5s2pf	509	1	Thus	thus	RB
cord-256444-grw5s2pf	509	2	,	,	,
cord-256444-grw5s2pf	509	3	the	the	DT
cord-256444-grw5s2pf	509	4	HE	HE	NNP
cord-256444-grw5s2pf	509	5	and	and	CC
cord-256444-grw5s2pf	509	6	S	S	NNP
cord-256444-grw5s2pf	509	7	proteins	protein	NNS
cord-256444-grw5s2pf	509	8	of	of	IN
cord-256444-grw5s2pf	509	9	various	various	JJ
cord-256444-grw5s2pf	509	10	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	509	11	may	may	MD
cord-256444-grw5s2pf	509	12	have	have	VB
cord-256444-grw5s2pf	509	13	comparable	comparable	JJ
cord-256444-grw5s2pf	509	14	functions	function	NNS
cord-256444-grw5s2pf	509	15	,	,	,
cord-256444-grw5s2pf	509	16	enabling	enable	VBG
cord-256444-grw5s2pf	509	17	the	the	DT
cord-256444-grw5s2pf	509	18	virus	virus	NN
cord-256444-grw5s2pf	509	19	to	to	TO
cord-256444-grw5s2pf	509	20	bind	bind	VB
cord-256444-grw5s2pf	509	21	the	the	DT
cord-256444-grw5s2pf	509	22	sialic	sialic	JJ
cord-256444-grw5s2pf	509	23	acid	acid	NN
cord-256444-grw5s2pf	509	24	residues	residue	NNS
cord-256444-grw5s2pf	509	25	;	;	:
cord-256444-grw5s2pf	509	26	however	however	RB
cord-256444-grw5s2pf	509	27	,	,	,
cord-256444-grw5s2pf	509	28	only	only	RB
cord-256444-grw5s2pf	509	29	the	the	DT
cord-256444-grw5s2pf	509	30	HE	HE	NNP
cord-256444-grw5s2pf	509	31	protein	protein	NN
cord-256444-grw5s2pf	509	32	confers	confer	VBZ
cord-256444-grw5s2pf	509	33	the	the	DT
cord-256444-grw5s2pf	509	34	receptordestroying	receptordestroye	VBG
cord-256444-grw5s2pf	509	35	activity	activity	NN
cord-256444-grw5s2pf	509	36	.	.	.
cord-256444-grw5s2pf	510	1	The	the	DT
cord-256444-grw5s2pf	510	2	residue	residue	NN
cord-256444-grw5s2pf	510	3	necessary	necessary	JJ
cord-256444-grw5s2pf	510	4	for	for	IN
cord-256444-grw5s2pf	510	5	hemagglutination	hemagglutination	NN
cord-256444-grw5s2pf	510	6	by	by	IN
cord-256444-grw5s2pf	510	7	IBV	IBV	NNP
cord-256444-grw5s2pf	510	8	is	be	VBZ
cord-256444-grw5s2pf	510	9	A2,3-linked	A2,3-linked	NNP
cord-256444-grw5s2pf	510	10	N	N	NNP
cord-256444-grw5s2pf	510	11	-	-	HYPH
cord-256444-grw5s2pf	510	12	acetylneuraminic	acetylneuraminic	NNP
cord-256444-grw5s2pf	510	13	acid	acid	NN
cord-256444-grw5s2pf	510	14	.	.	.
cord-256444-grw5s2pf	511	1	Curiously	curiously	RB
cord-256444-grw5s2pf	511	2	,	,	,
cord-256444-grw5s2pf	511	3	the	the	DT
cord-256444-grw5s2pf	511	4	hemagglutinating	hemagglutinate	VBG
cord-256444-grw5s2pf	511	5	activity	activity	NN
cord-256444-grw5s2pf	511	6	of	of	IN
cord-256444-grw5s2pf	511	7	IBV	IBV	NNP
cord-256444-grw5s2pf	511	8	is	be	VBZ
cord-256444-grw5s2pf	511	9	not	not	RB
cord-256444-grw5s2pf	511	10	evident	evident	JJ
cord-256444-grw5s2pf	511	11	until	until	IN
cord-256444-grw5s2pf	511	12	the	the	DT
cord-256444-grw5s2pf	511	13	virus	virus	NN
cord-256444-grw5s2pf	511	14	particle	particle	NN
cord-256444-grw5s2pf	511	15	is	be	VBZ
cord-256444-grw5s2pf	511	16	treated	treat	VBN
cord-256444-grw5s2pf	511	17	with	with	IN
cord-256444-grw5s2pf	511	18	neuraminidase	neuraminidase	NN
cord-256444-grw5s2pf	511	19	,	,	,
cord-256444-grw5s2pf	511	20	suggesting	suggest	VBG
cord-256444-grw5s2pf	511	21	that	that	IN
cord-256444-grw5s2pf	511	22	the	the	DT
cord-256444-grw5s2pf	511	23	S	S	NNP
cord-256444-grw5s2pf	511	24	protein	protein	NN
cord-256444-grw5s2pf	511	25	itself	-PRON-	PRP
cord-256444-grw5s2pf	511	26	is	be	VBZ
cord-256444-grw5s2pf	511	27	covered	cover	VBN
cord-256444-grw5s2pf	511	28	by	by	IN
cord-256444-grw5s2pf	511	29	sialic	sialic	JJ
cord-256444-grw5s2pf	511	30	acid	acid	NN
cord-256444-grw5s2pf	511	31	.	.	.
cord-256444-grw5s2pf	512	1	Although	although	IN
cord-256444-grw5s2pf	512	2	virus	virus	NN
cord-256444-grw5s2pf	512	3	binding	bind	VBG
cord-256444-grw5s2pf	512	4	to	to	IN
cord-256444-grw5s2pf	512	5	erythrocytes	erythrocyte	NNS
cord-256444-grw5s2pf	512	6	provides	provide	VBZ
cord-256444-grw5s2pf	512	7	a	a	DT
cord-256444-grw5s2pf	512	8	good	good	JJ
cord-256444-grw5s2pf	512	9	model	model	NN
cord-256444-grw5s2pf	512	10	system	system	NN
cord-256444-grw5s2pf	512	11	for	for	IN
cord-256444-grw5s2pf	512	12	studying	study	VBG
cord-256444-grw5s2pf	512	13	virus	virus	NN
cord-256444-grw5s2pf	512	14	-	-	HYPH
cord-256444-grw5s2pf	512	15	cell	cell	NN
cord-256444-grw5s2pf	512	16	interactions	interaction	NNS
cord-256444-grw5s2pf	512	17	,	,	,
cord-256444-grw5s2pf	512	18	it	-PRON-	PRP
cord-256444-grw5s2pf	512	19	may	may	MD
cord-256444-grw5s2pf	512	20	not	not	RB
cord-256444-grw5s2pf	512	21	necessarily	necessarily	RB
cord-256444-grw5s2pf	512	22	reflect	reflect	VB
cord-256444-grw5s2pf	512	23	the	the	DT
cord-256444-grw5s2pf	512	24	actual	actual	JJ
cord-256444-grw5s2pf	512	25	mechanism	mechanism	NN
cord-256444-grw5s2pf	512	26	of	of	IN
cord-256444-grw5s2pf	512	27	virus	virus	NN
cord-256444-grw5s2pf	512	28	attachment	attachment	NN
cord-256444-grw5s2pf	512	29	to	to	TO
cord-256444-grw5s2pf	512	30	target	target	VB
cord-256444-grw5s2pf	512	31	cells	cell	NNS
cord-256444-grw5s2pf	512	32	.	.	.
cord-256444-grw5s2pf	513	1	The	the	DT
cord-256444-grw5s2pf	513	2	classical	classical	JJ
cord-256444-grw5s2pf	513	3	study	study	NN
cord-256444-grw5s2pf	513	4	of	of	IN
cord-256444-grw5s2pf	513	5	virus	virus	NN
cord-256444-grw5s2pf	513	6	attachment	attachment	NN
cord-256444-grw5s2pf	513	7	to	to	TO
cord-256444-grw5s2pf	513	8	target	target	VB
cord-256444-grw5s2pf	513	9	cells	cell	NNS
cord-256444-grw5s2pf	513	10	involved	involve	VBN
cord-256444-grw5s2pf	513	11	the	the	DT
cord-256444-grw5s2pf	513	12	in	in	IN
cord-256444-grw5s2pf	513	13	uitro	uitro	NNP
cord-256444-grw5s2pf	513	14	binding	binding	NN
cord-256444-grw5s2pf	513	15	of	of	IN
cord-256444-grw5s2pf	513	16	MHV	MHV	NNP
cord-256444-grw5s2pf	513	17	to	to	TO
cord-256444-grw5s2pf	513	18	macrophages	macrophage	NNS
cord-256444-grw5s2pf	513	19	from	from	IN
cord-256444-grw5s2pf	513	20	genetically	genetically	RB
cord-256444-grw5s2pf	513	21	susceptible	susceptible	JJ
cord-256444-grw5s2pf	513	22	M	m	NN
cord-256444-grw5s2pf	513	23	I	i	NN
cord-256444-grw5s2pf	513	24	C	c	NN
cord-256444-grw5s2pf	513	25	W	W	NNP
cord-256444-grw5s2pf	513	26	L	L	NNP
cord-256444-grw5s2pf	513	27	M.	M.	NNP
cord-256444-grw5s2pf	513	28	C.	C.	NNP
cord-256444-grw5s2pf	513	29	LAI	LAI	NNP
cord-256444-grw5s2pf	513	30	AND	and	CC
cord-256444-grw5s2pf	513	31	DAVID	DAVID	NNP
cord-256444-grw5s2pf	513	32	CAVANAGH	CAVANAGH	NNP
cord-256444-grw5s2pf	513	33	and	and	CC
cord-256444-grw5s2pf	513	34	resistant	resistant	JJ
cord-256444-grw5s2pf	513	35	mouse	mouse	NN
cord-256444-grw5s2pf	513	36	strains	strain	NNS
cord-256444-grw5s2pf	513	37	(	(	-LRB-
cord-256444-grw5s2pf	513	38	Shif	Shif	NNP
cord-256444-grw5s2pf	513	39	and	and	CC
cord-256444-grw5s2pf	513	40	Bang	Bang	NNP
cord-256444-grw5s2pf	513	41	,	,	,
cord-256444-grw5s2pf	513	42	1970	1970	CD
cord-256444-grw5s2pf	513	43	)	)	-RRB-
cord-256444-grw5s2pf	513	44	.	.	.
cord-256444-grw5s2pf	514	1	This	this	DT
cord-256444-grw5s2pf	514	2	study	study	NN
cord-256444-grw5s2pf	514	3	showed	show	VBD
cord-256444-grw5s2pf	514	4	that	that	IN
cord-256444-grw5s2pf	514	5	MHV	MHV	NNP
cord-256444-grw5s2pf	514	6	bound	bind	VBN
cord-256444-grw5s2pf	514	7	equally	equally	RB
cord-256444-grw5s2pf	514	8	well	well	RB
cord-256444-grw5s2pf	514	9	to	to	TO
cord-256444-grw5s2pf	514	10	cells	cell	NNS
cord-256444-grw5s2pf	514	11	from	from	IN
cord-256444-grw5s2pf	514	12	resistant	resistant	JJ
cord-256444-grw5s2pf	514	13	and	and	CC
cord-256444-grw5s2pf	514	14	susceptible	susceptible	JJ
cord-256444-grw5s2pf	514	15	mice	mouse	NNS
cord-256444-grw5s2pf	514	16	,	,	,
cord-256444-grw5s2pf	514	17	even	even	RB
cord-256444-grw5s2pf	514	18	though	though	IN
cord-256444-grw5s2pf	514	19	macrophages	macrophage	NNS
cord-256444-grw5s2pf	514	20	from	from	IN
cord-256444-grw5s2pf	514	21	resistant	resistant	JJ
cord-256444-grw5s2pf	514	22	mice	mouse	NNS
cord-256444-grw5s2pf	514	23	were	be	VBD
cord-256444-grw5s2pf	514	24	resistant	resistant	JJ
cord-256444-grw5s2pf	514	25	to	to	IN
cord-256444-grw5s2pf	514	26	virus	virus	NN
cord-256444-grw5s2pf	514	27	infection	infection	NN
cord-256444-grw5s2pf	514	28	.	.	.
cord-256444-grw5s2pf	515	1	Similar	similar	JJ
cord-256444-grw5s2pf	515	2	observations	observation	NNS
cord-256444-grw5s2pf	515	3	have	have	VBP
cord-256444-grw5s2pf	515	4	been	be	VBN
cord-256444-grw5s2pf	515	5	made	make	VBN
cord-256444-grw5s2pf	515	6	on	on	IN
cord-256444-grw5s2pf	515	7	splenic	splenic	JJ
cord-256444-grw5s2pf	515	8	lymphocytes	lymphocyte	NNS
cord-256444-grw5s2pf	515	9	,	,	,
cord-256444-grw5s2pf	515	10	thymocytes	thymocyte	NNS
cord-256444-grw5s2pf	515	11	(	(	-LRB-
cord-256444-grw5s2pf	515	12	Krzystyniak	Krzystyniak	NNP
cord-256444-grw5s2pf	515	13	and	and	CC
cord-256444-grw5s2pf	515	14	Dupuy	Dupuy	NNP
cord-256444-grw5s2pf	515	15	,	,	,
cord-256444-grw5s2pf	515	16	19811	19811	CD
cord-256444-grw5s2pf	515	17	,	,	,
cord-256444-grw5s2pf	515	18	and	and	CC
cord-256444-grw5s2pf	515	19	glial	glial	JJ
cord-256444-grw5s2pf	515	20	cells	cell	NNS
cord-256444-grw5s2pf	515	21	(	(	-LRB-
cord-256444-grw5s2pf	515	22	Wilson	Wilson	NNP
cord-256444-grw5s2pf	515	23	and	and	CC
cord-256444-grw5s2pf	515	24	Dales	Dales	NNP
cord-256444-grw5s2pf	515	25	,	,	,
cord-256444-grw5s2pf	515	26	1988	1988	CD
cord-256444-grw5s2pf	515	27	)	)	-RRB-
cord-256444-grw5s2pf	515	28	;	;	:
cord-256444-grw5s2pf	515	29	thus	thus	RB
cord-256444-grw5s2pf	515	30	,	,	,
cord-256444-grw5s2pf	515	31	it	-PRON-	PRP
cord-256444-grw5s2pf	515	32	appears	appear	VBZ
cord-256444-grw5s2pf	515	33	that	that	IN
cord-256444-grw5s2pf	515	34	genetic	genetic	JJ
cord-256444-grw5s2pf	515	35	resistance	resistance	NN
cord-256444-grw5s2pf	515	36	is	be	VBZ
cord-256444-grw5s2pf	515	37	not	not	RB
cord-256444-grw5s2pf	515	38	exerted	exert	VBN
cord-256444-grw5s2pf	515	39	at	at	IN
cord-256444-grw5s2pf	515	40	the	the	DT
cord-256444-grw5s2pf	515	41	level	level	NN
cord-256444-grw5s2pf	515	42	of	of	IN
cord-256444-grw5s2pf	515	43	virus	virus	NN
cord-256444-grw5s2pf	515	44	binding	bind	VBG
cord-256444-grw5s2pf	515	45	in	in	IN
cord-256444-grw5s2pf	515	46	these	these	DT
cord-256444-grw5s2pf	515	47	cases	case	NNS
cord-256444-grw5s2pf	515	48	.	.	.
cord-256444-grw5s2pf	516	1	Similarly	similarly	RB
cord-256444-grw5s2pf	516	2	,	,	,
cord-256444-grw5s2pf	516	3	established	establish	VBN
cord-256444-grw5s2pf	516	4	tissue	tissue	NN
cord-256444-grw5s2pf	516	5	culture	culture	NN
cord-256444-grw5s2pf	516	6	cell	cell	NN
cord-256444-grw5s2pf	516	7	lines	line	NNS
cord-256444-grw5s2pf	516	8	,	,	,
cord-256444-grw5s2pf	516	9	including	include	VBG
cord-256444-grw5s2pf	516	10	murine	murine	JJ
cord-256444-grw5s2pf	516	11	and	and	CC
cord-256444-grw5s2pf	516	12	primate	primate	JJ
cord-256444-grw5s2pf	516	13	cells	cell	NNS
cord-256444-grw5s2pf	516	14	,	,	,
cord-256444-grw5s2pf	516	15	irrespective	irrespective	RB
cord-256444-grw5s2pf	516	16	of	of	IN
cord-256444-grw5s2pf	516	17	their	-PRON-	PRP$
cord-256444-grw5s2pf	516	18	degree	degree	NN
cord-256444-grw5s2pf	516	19	of	of	IN
cord-256444-grw5s2pf	516	20	susceptibility	susceptibility	NN
cord-256444-grw5s2pf	516	21	or	or	CC
cord-256444-grw5s2pf	516	22	resistance	resistance	NN
cord-256444-grw5s2pf	516	23	to	to	IN
cord-256444-grw5s2pf	516	24	MHV	MHV	NNP
cord-256444-grw5s2pf	516	25	,	,	,
cord-256444-grw5s2pf	516	26	bound	bind	VBN
cord-256444-grw5s2pf	516	27	MHV	MHV	NNP
cord-256444-grw5s2pf	516	28	to	to	IN
cord-256444-grw5s2pf	516	29	the	the	DT
cord-256444-grw5s2pf	516	30	same	same	JJ
cord-256444-grw5s2pf	516	31	extent	extent	NN
cord-256444-grw5s2pf	516	32	(	(	-LRB-
cord-256444-grw5s2pf	516	33	van	van	NNP
cord-256444-grw5s2pf	516	34	Dinter	Dinter	NNP
cord-256444-grw5s2pf	516	35	and	and	CC
cord-256444-grw5s2pf	516	36	Flintoff	Flintoff	NNP
cord-256444-grw5s2pf	516	37	,	,	,
cord-256444-grw5s2pf	516	38	1987	1987	CD
cord-256444-grw5s2pf	516	39	;	;	:
cord-256444-grw5s2pf	517	1	Kooi	Kooi	NNP
cord-256444-grw5s2pf	517	2	et	et	NNP
cord-256444-grw5s2pf	517	3	al	al	NNP
cord-256444-grw5s2pf	517	4	.	.	.
cord-256444-grw5s2pf	518	1	,	,	,
cord-256444-grw5s2pf	519	1	1988	1988	CD
cord-256444-grw5s2pf	519	2	Kooi	Kooi	NNP
cord-256444-grw5s2pf	519	3	et	et	NNP
cord-256444-grw5s2pf	519	4	al	al	NNP
cord-256444-grw5s2pf	519	5	.	.	NNP
cord-256444-grw5s2pf	519	6	,	,	,
cord-256444-grw5s2pf	519	7	,	,	,
cord-256444-grw5s2pf	519	8	1991	1991	CD
cord-256444-grw5s2pf	519	9	.	.	.
cord-256444-grw5s2pf	520	1	Thus	thus	RB
cord-256444-grw5s2pf	520	2	,	,	,
cord-256444-grw5s2pf	520	3	virus	virus	NN
cord-256444-grw5s2pf	520	4	may	may	MD
cord-256444-grw5s2pf	520	5	bind	bind	VB
cord-256444-grw5s2pf	520	6	to	to	IN
cord-256444-grw5s2pf	520	7	a	a	DT
cord-256444-grw5s2pf	520	8	ubiquitous	ubiquitous	JJ
cord-256444-grw5s2pf	520	9	molecule	molecule	NN
cord-256444-grw5s2pf	520	10	on	on	IN
cord-256444-grw5s2pf	520	11	the	the	DT
cord-256444-grw5s2pf	520	12	cell	cell	NN
cord-256444-grw5s2pf	520	13	surface	surface	NN
cord-256444-grw5s2pf	520	14	,	,	,
cord-256444-grw5s2pf	520	15	which	which	WDT
cord-256444-grw5s2pf	520	16	,	,	,
cord-256444-grw5s2pf	520	17	however	however	RB
cord-256444-grw5s2pf	520	18	,	,	,
cord-256444-grw5s2pf	520	19	may	may	MD
cord-256444-grw5s2pf	520	20	not	not	RB
cord-256444-grw5s2pf	520	21	lead	lead	VB
cord-256444-grw5s2pf	520	22	to	to	IN
cord-256444-grw5s2pf	520	23	virus	virus	NN
cord-256444-grw5s2pf	520	24	infection	infection	NN
cord-256444-grw5s2pf	520	25	.	.	.
cord-256444-grw5s2pf	521	1	Whether	whether	IN
cord-256444-grw5s2pf	521	2	this	this	DT
cord-256444-grw5s2pf	521	3	ubiquitous	ubiquitous	JJ
cord-256444-grw5s2pf	521	4	molecule	molecule	NN
cord-256444-grw5s2pf	521	5	is	be	VBZ
cord-256444-grw5s2pf	521	6	a	a	DT
cord-256444-grw5s2pf	521	7	sialic	sialic	JJ
cord-256444-grw5s2pf	521	8	acid	acid	NN
cord-256444-grw5s2pf	521	9	-	-	HYPH
cord-256444-grw5s2pf	521	10	containing	contain	VBG
cord-256444-grw5s2pf	521	11	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	521	12	has	have	VBZ
cord-256444-grw5s2pf	521	13	not	not	RB
cord-256444-grw5s2pf	521	14	been	be	VBN
cord-256444-grw5s2pf	521	15	established	establish	VBN
cord-256444-grw5s2pf	521	16	.	.	.
cord-256444-grw5s2pf	522	1	The	the	DT
cord-256444-grw5s2pf	522	2	binding	binding	NN
cord-256444-grw5s2pf	522	3	of	of	IN
cord-256444-grw5s2pf	522	4	BCV	BCV	NNP
cord-256444-grw5s2pf	522	5	to	to	IN
cord-256444-grw5s2pf	522	6	its	-PRON-	PRP$
cord-256444-grw5s2pf	522	7	target	target	NN
cord-256444-grw5s2pf	522	8	cells	cell	NNS
cord-256444-grw5s2pf	522	9	,	,	,
cord-256444-grw5s2pf	522	10	such	such	JJ
cord-256444-grw5s2pf	522	11	as	as	IN
cord-256444-grw5s2pf	522	12	MDCK	MDCK	NNP
cord-256444-grw5s2pf	522	13	cells	cell	NNS
cord-256444-grw5s2pf	522	14	,	,	,
cord-256444-grw5s2pf	522	15	is	be	VBZ
cord-256444-grw5s2pf	522	16	mediated	mediate	VBN
cord-256444-grw5s2pf	522	17	by	by	IN
cord-256444-grw5s2pf	522	18	9-O	9-o	CD
cord-256444-grw5s2pf	522	19	-	-	HYPH
cord-256444-grw5s2pf	522	20	acetylneuraminic	acetylneuraminic	JJ
cord-256444-grw5s2pf	522	21	acid	acid	NN
cord-256444-grw5s2pf	522	22	residues	residue	NNS
cord-256444-grw5s2pf	522	23	similar	similar	JJ
cord-256444-grw5s2pf	522	24	to	to	IN
cord-256444-grw5s2pf	522	25	those	those	DT
cord-256444-grw5s2pf	522	26	on	on	IN
cord-256444-grw5s2pf	522	27	erythrocytes	erythrocyte	NNS
cord-256444-grw5s2pf	522	28	.	.	.
cord-256444-grw5s2pf	523	1	Removal	removal	NN
cord-256444-grw5s2pf	523	2	of	of	IN
cord-256444-grw5s2pf	523	3	the	the	DT
cord-256444-grw5s2pf	523	4	sialic	sialic	JJ
cord-256444-grw5s2pf	523	5	acid	acid	NN
cord-256444-grw5s2pf	523	6	by	by	IN
cord-256444-grw5s2pf	523	7	neuraminidase	neuraminidase	NN
cord-256444-grw5s2pf	523	8	abolished	abolish	VBN
cord-256444-grw5s2pf	523	9	virus	virus	NN
cord-256444-grw5s2pf	523	10	attachment	attachment	NN
cord-256444-grw5s2pf	523	11	,	,	,
cord-256444-grw5s2pf	523	12	while	while	IN
cord-256444-grw5s2pf	523	13	resialization	resialization	NN
cord-256444-grw5s2pf	523	14	restored	restore	VBD
cord-256444-grw5s2pf	523	15	it	-PRON-	PRP
cord-256444-grw5s2pf	523	16	.	.	.
cord-256444-grw5s2pf	524	1	HCV	HCV	NNP
cord-256444-grw5s2pf	524	2	-	-	HYPH
cord-256444-grw5s2pf	524	3	OC43	OC43	NNP
cord-256444-grw5s2pf	524	4	binds	bind	VBZ
cord-256444-grw5s2pf	524	5	to	to	IN
cord-256444-grw5s2pf	524	6	a	a	DT
cord-256444-grw5s2pf	524	7	similar	similar	JJ
cord-256444-grw5s2pf	524	8	sialic	sialic	NN
cord-256444-grw5s2pf	524	9	acid	acid	NN
cord-256444-grw5s2pf	524	10	residue	residue	NN
cord-256444-grw5s2pf	524	11	but	but	CC
cord-256444-grw5s2pf	524	12	prefers	prefer	VBZ
cord-256444-grw5s2pf	524	13	a	a	DT
cord-256444-grw5s2pf	524	14	form	form	NN
cord-256444-grw5s2pf	524	15	slightly	slightly	RB
cord-256444-grw5s2pf	524	16	different	different	JJ
cord-256444-grw5s2pf	524	17	from	from	IN
cord-256444-grw5s2pf	524	18	that	that	DT
cord-256444-grw5s2pf	524	19	for	for	IN
cord-256444-grw5s2pf	524	20	BCV	BCV	NNP
cord-256444-grw5s2pf	524	21	(	(	-LRB-
cord-256444-grw5s2pf	524	22	Kunkel	Kunkel	NNP
cord-256444-grw5s2pf	524	23	and	and	CC
cord-256444-grw5s2pf	524	24	Herrler	Herrler	NNP
cord-256444-grw5s2pf	524	25	,	,	,
cord-256444-grw5s2pf	524	26	1993	1993	CD
cord-256444-grw5s2pf	524	27	)	)	-RRB-
cord-256444-grw5s2pf	524	28	.	.	.
cord-256444-grw5s2pf	525	1	The	the	DT
cord-256444-grw5s2pf	525	2	HE	HE	NNP
cord-256444-grw5s2pf	525	3	protein	protein	NN
cord-256444-grw5s2pf	525	4	of	of	IN
cord-256444-grw5s2pf	525	5	BCV	BCV	NNP
cord-256444-grw5s2pf	525	6	can	can	MD
cord-256444-grw5s2pf	525	7	also	also	RB
cord-256444-grw5s2pf	525	8	mediate	mediate	VB
cord-256444-grw5s2pf	525	9	virus	virus	NN
cord-256444-grw5s2pf	525	10	binding	bind	VBG
cord-256444-grw5s2pf	525	11	to	to	TO
cord-256444-grw5s2pf	525	12	target	target	VB
cord-256444-grw5s2pf	525	13	cells	cell	NNS
cord-256444-grw5s2pf	525	14	,	,	,
cord-256444-grw5s2pf	525	15	and	and	CC
cord-256444-grw5s2pf	525	16	this	this	DT
cord-256444-grw5s2pf	525	17	binding	binding	NN
cord-256444-grw5s2pf	525	18	may	may	MD
cord-256444-grw5s2pf	525	19	be	be	VB
cord-256444-grw5s2pf	525	20	required	require	VBN
cord-256444-grw5s2pf	525	21	for	for	IN
cord-256444-grw5s2pf	525	22	viral	viral	JJ
cord-256444-grw5s2pf	525	23	infection	infection	NN
cord-256444-grw5s2pf	525	24	,	,	,
cord-256444-grw5s2pf	525	25	as	as	IN
cord-256444-grw5s2pf	525	26	suggested	suggest	VBN
cord-256444-grw5s2pf	525	27	by	by	IN
cord-256444-grw5s2pf	525	28	the	the	DT
cord-256444-grw5s2pf	525	29	finding	finding	NN
cord-256444-grw5s2pf	525	30	that	that	IN
cord-256444-grw5s2pf	525	31	MAb	MAb	NNS
cord-256444-grw5s2pf	525	32	against	against	IN
cord-256444-grw5s2pf	525	33	HE	he	PRP
cord-256444-grw5s2pf	525	34	inhibited	inhibit	VBD
cord-256444-grw5s2pf	525	35	BCV	BCV	NNP
cord-256444-grw5s2pf	525	36	infectivity	infectivity	NN
cord-256444-grw5s2pf	525	37	(	(	-LRB-
cord-256444-grw5s2pf	525	38	Deregt	Deregt	NNP
cord-256444-grw5s2pf	525	39	and	and	CC
cord-256444-grw5s2pf	525	40	Babiuk	Babiuk	NNP
cord-256444-grw5s2pf	525	41	,	,	,
cord-256444-grw5s2pf	525	42	1987	1987	CD
cord-256444-grw5s2pf	525	43	;	;	:
cord-256444-grw5s2pf	526	1	Deregt	Deregt	NNP
cord-256444-grw5s2pf	526	2	et	et	FW
cord-256444-grw5s2pf	526	3	al	al	NNP
cord-256444-grw5s2pf	526	4	.	.	NNP
cord-256444-grw5s2pf	526	5	,	,	,
cord-256444-grw5s2pf	526	6	1989	1989	CD
cord-256444-grw5s2pf	526	7	)	)	-RRB-
cord-256444-grw5s2pf	526	8	.	.	.
cord-256444-grw5s2pf	527	1	One	one	CD
cord-256444-grw5s2pf	527	2	inhibitor	inhibitor	NN
cord-256444-grw5s2pf	527	3	of	of	IN
cord-256444-grw5s2pf	527	4	the	the	DT
cord-256444-grw5s2pf	527	5	esterase	esterase	NN
cord-256444-grw5s2pf	527	6	activity	activity	NN
cord-256444-grw5s2pf	527	7	of	of	IN
cord-256444-grw5s2pf	527	8	HE	HE	NNP
cord-256444-grw5s2pf	527	9	protein	protein	NN
cord-256444-grw5s2pf	527	10	,	,	,
cord-256444-grw5s2pf	527	11	diisopropylfluorophosphate	diisopropylfluorophosphate	NNP
cord-256444-grw5s2pf	527	12	,	,	,
cord-256444-grw5s2pf	527	13	also	also	RB
cord-256444-grw5s2pf	527	14	inhibited	inhibit	VBD
cord-256444-grw5s2pf	527	15	BCV	BCV	NNP
cord-256444-grw5s2pf	527	16	infection	infection	NN
cord-256444-grw5s2pf	527	17	(	(	-LRB-
cord-256444-grw5s2pf	527	18	Vlasak	Vlasak	NNP
cord-256444-grw5s2pf	527	19	et	et	NNP
cord-256444-grw5s2pf	527	20	al	al	NNP
cord-256444-grw5s2pf	527	21	.	.	NNP
cord-256444-grw5s2pf	527	22	,	,	,
cord-256444-grw5s2pf	527	23	1988a	1988a	CD
cord-256444-grw5s2pf	527	24	)	)	-RRB-
cord-256444-grw5s2pf	527	25	.	.	.
cord-256444-grw5s2pf	528	1	The	the	DT
cord-256444-grw5s2pf	528	2	S	S	NNP
cord-256444-grw5s2pf	528	3	protein	protein	NN
cord-256444-grw5s2pf	528	4	of	of	IN
cord-256444-grw5s2pf	528	5	BCV	BCV	NNP
cord-256444-grw5s2pf	528	6	probably	probably	RB
cord-256444-grw5s2pf	528	7	also	also	RB
cord-256444-grw5s2pf	528	8	participates	participate	VBZ
cord-256444-grw5s2pf	528	9	in	in	IN
cord-256444-grw5s2pf	528	10	virus	virus	NN
cord-256444-grw5s2pf	528	11	binding	bind	VBG
cord-256444-grw5s2pf	528	12	to	to	TO
cord-256444-grw5s2pf	528	13	target	target	NN
cord-256444-grw5s2pf	528	14	cells	cell	NNS
cord-256444-grw5s2pf	528	15	,	,	,
cord-256444-grw5s2pf	528	16	as	as	IN
cord-256444-grw5s2pf	528	17	suggested	suggest	VBN
cord-256444-grw5s2pf	528	18	by	by	IN
cord-256444-grw5s2pf	528	19	the	the	DT
cord-256444-grw5s2pf	528	20	finding	finding	NN
cord-256444-grw5s2pf	528	21	that	that	IN
cord-256444-grw5s2pf	528	22	the	the	DT
cord-256444-grw5s2pf	528	23	MAb	MAb	NNS
cord-256444-grw5s2pf	528	24	against	against	IN
cord-256444-grw5s2pf	528	25	S	S	NNP
cord-256444-grw5s2pf	528	26	protein	protein	NN
cord-256444-grw5s2pf	528	27	can	can	MD
cord-256444-grw5s2pf	528	28	neutralize	neutralize	VB
cord-256444-grw5s2pf	528	29	BCV	BCV	NNP
cord-256444-grw5s2pf	528	30	infectivity	infectivity	NN
cord-256444-grw5s2pf	528	31	.	.	.
cord-256444-grw5s2pf	529	1	The	the	DT
cord-256444-grw5s2pf	529	2	relative	relative	JJ
cord-256444-grw5s2pf	529	3	importance	importance	NN
cord-256444-grw5s2pf	529	4	of	of	IN
cord-256444-grw5s2pf	529	5	S	s	NN
cord-256444-grw5s2pf	530	1	and	and	CC
cord-256444-grw5s2pf	530	2	HE	HE	NNP
cord-256444-grw5s2pf	530	3	proteins	protein	VBZ
cord-256444-grw5s2pf	530	4	is	be	VBZ
cord-256444-grw5s2pf	530	5	not	not	RB
cord-256444-grw5s2pf	530	6	clear	clear	JJ
cord-256444-grw5s2pf	530	7	.	.	.
cord-256444-grw5s2pf	531	1	In	in	IN
cord-256444-grw5s2pf	531	2	contrast	contrast	NN
cord-256444-grw5s2pf	531	3	,	,	,
cord-256444-grw5s2pf	531	4	none	none	NN
cord-256444-grw5s2pf	531	5	of	of	IN
cord-256444-grw5s2pf	531	6	the	the	DT
cord-256444-grw5s2pf	531	7	MAb	MAb	NNS
cord-256444-grw5s2pf	531	8	against	against	IN
cord-256444-grw5s2pf	531	9	the	the	DT
cord-256444-grw5s2pf	531	10	HE	HE	NNP
cord-256444-grw5s2pf	531	11	protein	protein	NN
cord-256444-grw5s2pf	531	12	of	of	IN
cord-256444-grw5s2pf	531	13	MHV	MHV	NNP
cord-256444-grw5s2pf	531	14	inhibited	inhibit	VBD
cord-256444-grw5s2pf	531	15	MHV	MHV	NNP
cord-256444-grw5s2pf	531	16	infection	infection	NN
cord-256444-grw5s2pf	531	17	.	.	.
cord-256444-grw5s2pf	532	1	Despite	despite	IN
cord-256444-grw5s2pf	532	2	the	the	DT
cord-256444-grw5s2pf	532	3	finding	finding	NN
cord-256444-grw5s2pf	532	4	that	that	IN
cord-256444-grw5s2pf	532	5	the	the	DT
cord-256444-grw5s2pf	532	6	binding	binding	NN
cord-256444-grw5s2pf	532	7	of	of	IN
cord-256444-grw5s2pf	532	8	HE	HE	NNP
cord-256444-grw5s2pf	532	9	and	and	CC
cord-256444-grw5s2pf	532	10	S	S	NNP
cord-256444-grw5s2pf	532	11	proteins	protein	NNS
cord-256444-grw5s2pf	532	12	to	to	TO
cord-256444-grw5s2pf	532	13	target	target	VB
cord-256444-grw5s2pf	532	14	cells	cell	NNS
cord-256444-grw5s2pf	532	15	is	be	VBZ
cord-256444-grw5s2pf	532	16	necessary	necessary	JJ
cord-256444-grw5s2pf	532	17	for	for	IN
cord-256444-grw5s2pf	532	18	BCV	BCV	NNP
cord-256444-grw5s2pf	532	19	infection	infection	NN
cord-256444-grw5s2pf	532	20	,	,	,
cord-256444-grw5s2pf	532	21	the	the	DT
cord-256444-grw5s2pf	532	22	binding	binding	NN
cord-256444-grw5s2pf	532	23	of	of	IN
cord-256444-grw5s2pf	532	24	BCV	BCV	NNP
cord-256444-grw5s2pf	532	25	or	or	CC
cord-256444-grw5s2pf	532	26	HCV	HCV	NNP
cord-256444-grw5s2pf	532	27	-	-	HYPH
cord-256444-grw5s2pf	532	28	OC43	OC43	NNP
cord-256444-grw5s2pf	532	29	to	to	IN
cord-256444-grw5s2pf	532	30	N	n	CD
cord-256444-grw5s2pf	532	31	-	-	HYPH
cord-256444-grw5s2pf	532	32	acetylneuraminic	acetylneuraminic	JJ
cord-256444-grw5s2pf	532	33	acid	acid	NN
cord-256444-grw5s2pf	532	34	in	in	IN
cord-256444-grw5s2pf	532	35	itself	-PRON-	PRP
cord-256444-grw5s2pf	532	36	is	be	VBZ
cord-256444-grw5s2pf	532	37	not	not	RB
cord-256444-grw5s2pf	532	38	likely	likely	JJ
cord-256444-grw5s2pf	532	39	the	the	DT
cord-256444-grw5s2pf	532	40	basis	basis	NN
cord-256444-grw5s2pf	532	41	of	of	IN
cord-256444-grw5s2pf	532	42	viral	viral	JJ
cord-256444-grw5s2pf	532	43	cell	cell	NN
cord-256444-grw5s2pf	532	44	tropism	tropism	NN
cord-256444-grw5s2pf	532	45	because	because	IN
cord-256444-grw5s2pf	532	46	sialic	sialic	JJ
cord-256444-grw5s2pf	532	47	acid	acid	NN
cord-256444-grw5s2pf	532	48	is	be	VBZ
cord-256444-grw5s2pf	532	49	a	a	DT
cord-256444-grw5s2pf	532	50	common	common	JJ
cord-256444-grw5s2pf	532	51	cell	cell	NN
cord-256444-grw5s2pf	532	52	surface	surface	NN
cord-256444-grw5s2pf	532	53	carbohydrate	carbohydrate	NN
cord-256444-grw5s2pf	532	54	residue	residue	NN
cord-256444-grw5s2pf	532	55	;	;	:
cord-256444-grw5s2pf	532	56	thus	thus	RB
cord-256444-grw5s2pf	532	57	,	,	,
cord-256444-grw5s2pf	532	58	an	an	DT
cord-256444-grw5s2pf	532	59	additional	additional	JJ
cord-256444-grw5s2pf	532	60	,	,	,
cord-256444-grw5s2pf	532	61	more	more	JJR
cord-256444-grw5s2pf	532	62	cell	cell	NN
cord-256444-grw5s2pf	532	63	type	type	NN
cord-256444-grw5s2pf	532	64	-	-	HYPH
cord-256444-grw5s2pf	532	65	specific	specific	JJ
cord-256444-grw5s2pf	532	66	molecule	molecule	NN
cord-256444-grw5s2pf	532	67	is	be	VBZ
cord-256444-grw5s2pf	532	68	probably	probably	RB
cord-256444-grw5s2pf	532	69	required	require	VBN
cord-256444-grw5s2pf	532	70	for	for	IN
cord-256444-grw5s2pf	532	71	viral	viral	JJ
cord-256444-grw5s2pf	532	72	infection	infection	NN
cord-256444-grw5s2pf	532	73	.	.	.
cord-256444-grw5s2pf	533	1	The	the	DT
cord-256444-grw5s2pf	533	2	finding	finding	NN
cord-256444-grw5s2pf	533	3	that	that	IN
cord-256444-grw5s2pf	533	4	MHV	MHV	NNP
cord-256444-grw5s2pf	533	5	and	and	CC
cord-256444-grw5s2pf	533	6	other	other	JJ
cord-256444-grw5s2pf	533	7	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	533	8	bound	bind	VBN
cord-256444-grw5s2pf	533	9	to	to	TO
cord-256444-grw5s2pf	533	10	resistant	resistant	VB
cord-256444-grw5s2pf	533	11	as	as	RB
cord-256444-grw5s2pf	533	12	well	well	RB
cord-256444-grw5s2pf	533	13	as	as	IN
cord-256444-grw5s2pf	533	14	susceptible	susceptible	JJ
cord-256444-grw5s2pf	533	15	cells	cell	NNS
cord-256444-grw5s2pf	533	16	indicates	indicate	VBZ
cord-256444-grw5s2pf	533	17	that	that	IN
cord-256444-grw5s2pf	533	18	this	this	DT
cord-256444-grw5s2pf	533	19	binding	binding	NN
cord-256444-grw5s2pf	533	20	may	may	MD
cord-256444-grw5s2pf	533	21	represent	represent	VB
cord-256444-grw5s2pf	533	22	an	an	DT
cord-256444-grw5s2pf	533	23	initial	initial	JJ
cord-256444-grw5s2pf	533	24	step	step	NN
cord-256444-grw5s2pf	533	25	in	in	IN
cord-256444-grw5s2pf	533	26	the	the	DT
cord-256444-grw5s2pf	533	27	virus	virus	NN
cord-256444-grw5s2pf	533	28	attachment	attachment	NN
cord-256444-grw5s2pf	533	29	process	process	NN
cord-256444-grw5s2pf	533	30	,	,	,
cord-256444-grw5s2pf	533	31	which	which	WDT
cord-256444-grw5s2pf	533	32	is	be	VBZ
cord-256444-grw5s2pf	533	33	not	not	RB
cord-256444-grw5s2pf	533	34	sufficient	sufficient	JJ
cord-256444-grw5s2pf	533	35	for	for	IN
cord-256444-grw5s2pf	533	36	viral	viral	JJ
cord-256444-grw5s2pf	533	37	infection	infection	NN
cord-256444-grw5s2pf	533	38	.	.	.
cord-256444-grw5s2pf	534	1	It	-PRON-	PRP
cord-256444-grw5s2pf	534	2	is	be	VBZ
cord-256444-grw5s2pf	534	3	likely	likely	JJ
cord-256444-grw5s2pf	534	4	that	that	IN
cord-256444-grw5s2pf	534	5	a	a	DT
cord-256444-grw5s2pf	534	6	more	more	RBR
cord-256444-grw5s2pf	534	7	specific	specific	JJ
cord-256444-grw5s2pf	534	8	binding	binding	NN
cord-256444-grw5s2pf	534	9	between	between	IN
cord-256444-grw5s2pf	534	10	virus	virus	NN
cord-256444-grw5s2pf	534	11	and	and	CC
cord-256444-grw5s2pf	534	12	cells	cell	NNS
cord-256444-grw5s2pf	534	13	is	be	VBZ
cord-256444-grw5s2pf	534	14	required	require	VBN
cord-256444-grw5s2pf	534	15	for	for	IN
cord-256444-grw5s2pf	534	16	the	the	DT
cord-256444-grw5s2pf	534	17	establishment	establishment	NN
cord-256444-grw5s2pf	534	18	of	of	IN
cord-256444-grw5s2pf	534	19	viral	viral	JJ
cord-256444-grw5s2pf	534	20	infection	infection	NN
cord-256444-grw5s2pf	534	21	.	.	.
cord-256444-grw5s2pf	535	1	This	this	DT
cord-256444-grw5s2pf	535	2	binding	binding	NN
cord-256444-grw5s2pf	535	3	involves	involve	VBZ
cord-256444-grw5s2pf	535	4	a	a	DT
cord-256444-grw5s2pf	535	5	specific	specific	JJ
cord-256444-grw5s2pf	535	6	virus	virus	NN
cord-256444-grw5s2pf	535	7	receptor	receptor	NN
cord-256444-grw5s2pf	535	8	molecule	molecule	NN
cord-256444-grw5s2pf	535	9	on	on	IN
cord-256444-grw5s2pf	535	10	the	the	DT
cord-256444-grw5s2pf	535	11	cell	cell	NN
cord-256444-grw5s2pf	535	12	surface	surface	NN
cord-256444-grw5s2pf	535	13	.	.	.
cord-256444-grw5s2pf	536	1	a.	a.	NN
cord-256444-grw5s2pf	536	2	MHV	MHV	NNP
cord-256444-grw5s2pf	536	3	Receptor	Receptor	NNP
cord-256444-grw5s2pf	536	4	.	.	.
cord-256444-grw5s2pf	537	1	The	the	DT
cord-256444-grw5s2pf	537	2	MHV	MHV	NNP
cord-256444-grw5s2pf	537	3	receptor	receptor	NN
cord-256444-grw5s2pf	537	4	was	be	VBD
cord-256444-grw5s2pf	537	5	the	the	DT
cord-256444-grw5s2pf	537	6	first	first	JJ
cord-256444-grw5s2pf	537	7	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	537	8	receptor	receptor	NN
cord-256444-grw5s2pf	537	9	to	to	TO
cord-256444-grw5s2pf	537	10	be	be	VB
cord-256444-grw5s2pf	537	11	identified	identify	VBN
cord-256444-grw5s2pf	537	12	.	.	.
cord-256444-grw5s2pf	538	1	It	-PRON-	PRP
cord-256444-grw5s2pf	538	2	is	be	VBZ
cord-256444-grw5s2pf	538	3	the	the	DT
cord-256444-grw5s2pf	538	4	murine	murine	JJ
cord-256444-grw5s2pf	538	5	homolog	homolog	NN
cord-256444-grw5s2pf	538	6	of	of	IN
cord-256444-grw5s2pf	538	7	a	a	DT
cord-256444-grw5s2pf	538	8	member	member	NN
cord-256444-grw5s2pf	538	9	of	of	IN
cord-256444-grw5s2pf	538	10	the	the	DT
cord-256444-grw5s2pf	538	11	carcinoembryonic	carcinoembryonic	NNP
cord-256444-grw5s2pf	538	12	antigen	antigen	NNP
cord-256444-grw5s2pf	538	13	(	(	-LRB-
cord-256444-grw5s2pf	538	14	CEA	CEA	NNP
cord-256444-grw5s2pf	538	15	)	)	-RRB-
cord-256444-grw5s2pf	538	16	family	family	NN
cord-256444-grw5s2pf	538	17	(	(	-LRB-
cord-256444-grw5s2pf	538	18	Dveksler	Dveksler	NNP
cord-256444-grw5s2pf	538	19	et	et	NNP
cord-256444-grw5s2pf	538	20	al	al	NNP
cord-256444-grw5s2pf	538	21	.	.	NNP
cord-256444-grw5s2pf	538	22	,	,	,
cord-256444-grw5s2pf	538	23	1991	1991	CD
cord-256444-grw5s2pf	538	24	;	;	:
cord-256444-grw5s2pf	538	25	Williams	Williams	NNP
cord-256444-grw5s2pf	538	26	et	et	NNP
cord-256444-grw5s2pf	538	27	al	al	NNP
cord-256444-grw5s2pf	538	28	.	.	NNP
cord-256444-grw5s2pf	538	29	,	,	,
cord-256444-grw5s2pf	538	30	1991	1991	CD
cord-256444-grw5s2pf	538	31	)	)	-RRB-
cord-256444-grw5s2pf	538	32	and	and	CC
cord-256444-grw5s2pf	538	33	belongs	belong	VBZ
cord-256444-grw5s2pf	538	34	to	to	IN
cord-256444-grw5s2pf	538	35	the	the	DT
cord-256444-grw5s2pf	538	36	biliary	biliary	JJ
cord-256444-grw5s2pf	538	37	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	538	38	(	(	-LRB-
cord-256444-grw5s2pf	538	39	bgp	bgp	NN
cord-256444-grw5s2pf	538	40	)	)	-RRB-
cord-256444-grw5s2pf	538	41	subfamily	subfamily	NN
cord-256444-grw5s2pf	538	42	.	.	.
cord-256444-grw5s2pf	539	1	The	the	DT
cord-256444-grw5s2pf	539	2	terminology	terminology	NN
cord-256444-grw5s2pf	539	3	of	of	IN
cord-256444-grw5s2pf	539	4	MHV	MHV	NNP
cord-256444-grw5s2pf	539	5	receptors	receptor	NNS
cord-256444-grw5s2pf	539	6	in	in	IN
cord-256444-grw5s2pf	539	7	the	the	DT
cord-256444-grw5s2pf	539	8	literature	literature	NN
cord-256444-grw5s2pf	539	9	is	be	VBZ
cord-256444-grw5s2pf	539	10	somewhat	somewhat	RB
cord-256444-grw5s2pf	539	11	controversial	controversial	JJ
cord-256444-grw5s2pf	539	12	,	,	,
cord-256444-grw5s2pf	539	13	the	the	DT
cord-256444-grw5s2pf	539	14	following	follow	VBG
cord-256444-grw5s2pf	539	15	terms	term	NNS
cord-256444-grw5s2pf	539	16	being	be	VBG
cord-256444-grw5s2pf	539	17	used	use	VBN
cord-256444-grw5s2pf	539	18	interchangeably	interchangeably	RB
cord-256444-grw5s2pf	539	19	:	:	:
cord-256444-grw5s2pf	539	20	mmCGM1	mmCGM1	NNP
cord-256444-grw5s2pf	539	21	,	,	,
cord-256444-grw5s2pf	539	22	MHVR-1	MHVR-1	NNP
cord-256444-grw5s2pf	539	23	,	,	,
cord-256444-grw5s2pf	539	24	and	and	CC
cord-256444-grw5s2pf	539	25	BgpA.	bgpa.	NN
cord-256444-grw5s2pf	540	1	It	-PRON-	PRP
cord-256444-grw5s2pf	540	2	has	have	VBZ
cord-256444-grw5s2pf	540	3	an	an	DT
cord-256444-grw5s2pf	540	4	immunoglobulin	immunoglobulin	NN
cord-256444-grw5s2pf	540	5	-	-	HYPH
cord-256444-grw5s2pf	540	6	like	like	JJ
cord-256444-grw5s2pf	540	7	structure	structure	NN
cord-256444-grw5s2pf	540	8	,	,	,
cord-256444-grw5s2pf	540	9	consisting	consist	VBG
cord-256444-grw5s2pf	540	10	of	of	IN
cord-256444-grw5s2pf	540	11	four	four	CD
cord-256444-grw5s2pf	540	12	immunoglubulin	immunoglubulin	NN
cord-256444-grw5s2pf	540	13	-	-	HYPH
cord-256444-grw5s2pf	540	14	like	like	JJ
cord-256444-grw5s2pf	540	15	loops	loop	NNS
cord-256444-grw5s2pf	540	16	,	,	,
cord-256444-grw5s2pf	540	17	the	the	DT
cord-256444-grw5s2pf	540	18	N	n	CD
cord-256444-grw5s2pf	540	19	-	-	HYPH
cord-256444-grw5s2pf	540	20	terminal	terminal	NN
cord-256444-grw5s2pf	540	21	loop	loop	NN
cord-256444-grw5s2pf	540	22	being	be	VBG
cord-256444-grw5s2pf	540	23	the	the	DT
cord-256444-grw5s2pf	540	24	virus	virus	NN
cord-256444-grw5s2pf	540	25	-	-	HYPH
cord-256444-grw5s2pf	540	26	binding	bind	VBG
cord-256444-grw5s2pf	540	27	domain	domain	NN
cord-256444-grw5s2pf	540	28	(	(	-LRB-
cord-256444-grw5s2pf	540	29	Dveksler	Dveksler	NNP
cord-256444-grw5s2pf	540	30	et	et	FW
cord-256444-grw5s2pf	540	31	al	al	NNP
cord-256444-grw5s2pf	540	32	.	.	NNP
cord-256444-grw5s2pf	540	33	,	,	,
cord-256444-grw5s2pf	540	34	1993b	1993b	CD
cord-256444-grw5s2pf	540	35	)	)	-RRB-
cord-256444-grw5s2pf	540	36	.	.	.
cord-256444-grw5s2pf	541	1	The	the	DT
cord-256444-grw5s2pf	541	2	sequence	sequence	NN
cord-256444-grw5s2pf	541	3	of	of	IN
cord-256444-grw5s2pf	541	4	the	the	DT
cord-256444-grw5s2pf	541	5	C	C	NNP
cord-256444-grw5s2pf	541	6	terminus	terminus	NN
cord-256444-grw5s2pf	541	7	(	(	-LRB-
cord-256444-grw5s2pf	541	8	cytoplasmic	cytoplasmic	JJ
cord-256444-grw5s2pf	541	9	domain	domain	NN
cord-256444-grw5s2pf	541	10	)	)	-RRB-
cord-256444-grw5s2pf	541	11	of	of	IN
cord-256444-grw5s2pf	541	12	the	the	DT
cord-256444-grw5s2pf	541	13	receptor	receptor	NN
cord-256444-grw5s2pf	541	14	is	be	VBZ
cord-256444-grw5s2pf	541	15	not	not	RB
cord-256444-grw5s2pf	541	16	essential	essential	JJ
cord-256444-grw5s2pf	541	17	.	.	.
cord-256444-grw5s2pf	542	1	Glycosylation	glycosylation	NN
cord-256444-grw5s2pf	542	2	of	of	IN
cord-256444-grw5s2pf	542	3	the	the	DT
cord-256444-grw5s2pf	542	4	protein	protein	NN
cord-256444-grw5s2pf	542	5	also	also	RB
cord-256444-grw5s2pf	542	6	is	be	VBZ
cord-256444-grw5s2pf	542	7	not	not	RB
cord-256444-grw5s2pf	542	8	necessary	necessary	JJ
cord-256444-grw5s2pf	542	9	for	for	IN
cord-256444-grw5s2pf	542	10	its	-PRON-	PRP$
cord-256444-grw5s2pf	542	11	receptor	receptor	NN
cord-256444-grw5s2pf	542	12	function	function	NN
cord-256444-grw5s2pf	542	13	in	in	IN
cord-256444-grw5s2pf	542	14	uiuo	uiuo	NN
cord-256444-grw5s2pf	543	1	(	(	-LRB-
cord-256444-grw5s2pf	543	2	Dveksler	Dveksler	NNP
cord-256444-grw5s2pf	543	3	et	et	FW
cord-256444-grw5s2pf	543	4	al	al	NNP
cord-256444-grw5s2pf	543	5	.	.	NNP
cord-256444-grw5s2pf	543	6	,	,	,
cord-256444-grw5s2pf	543	7	1995	1995	CD
cord-256444-grw5s2pf	543	8	)	)	-RRB-
cord-256444-grw5s2pf	543	9	.	.	.
cord-256444-grw5s2pf	544	1	The	the	DT
cord-256444-grw5s2pf	544	2	functional	functional	JJ
cord-256444-grw5s2pf	544	3	significance	significance	NN
cord-256444-grw5s2pf	544	4	of	of	IN
cord-256444-grw5s2pf	544	5	the	the	DT
cord-256444-grw5s2pf	544	6	receptor	receptor	NN
cord-256444-grw5s2pf	544	7	in	in	IN
cord-256444-grw5s2pf	544	8	viral	viral	JJ
cord-256444-grw5s2pf	544	9	infection	infection	NN
cord-256444-grw5s2pf	544	10	in	in	IN
cord-256444-grw5s2pf	544	11	uiuo	uiuo	NN
cord-256444-grw5s2pf	544	12	was	be	VBD
cord-256444-grw5s2pf	544	13	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	544	14	by	by	IN
cord-256444-grw5s2pf	544	15	the	the	DT
cord-256444-grw5s2pf	544	16	finding	finding	NN
cord-256444-grw5s2pf	544	17	that	that	IN
cord-256444-grw5s2pf	544	18	an	an	DT
cord-256444-grw5s2pf	544	19	MAb	MAb	NNS
cord-256444-grw5s2pf	544	20	against	against	IN
cord-256444-grw5s2pf	544	21	the	the	DT
cord-256444-grw5s2pf	544	22	MHV	MHV	NNP
cord-256444-grw5s2pf	544	23	receptor	receptor	NN
cord-256444-grw5s2pf	544	24	inhibited	inhibit	VBN
cord-256444-grw5s2pf	544	25	viral	viral	JJ
cord-256444-grw5s2pf	544	26	infection	infection	NN
cord-256444-grw5s2pf	544	27	in	in	IN
cord-256444-grw5s2pf	544	28	mice	mouse	NNS
cord-256444-grw5s2pf	544	29	(	(	-LRB-
cord-256444-grw5s2pf	544	30	Smith	Smith	NNP
cord-256444-grw5s2pf	544	31	et	et	NNP
cord-256444-grw5s2pf	544	32	al	al	NNP
cord-256444-grw5s2pf	544	33	.	.	NNP
cord-256444-grw5s2pf	544	34	,	,	,
cord-256444-grw5s2pf	544	35	1991	1991	CD
cord-256444-grw5s2pf	544	36	)	)	-RRB-
cord-256444-grw5s2pf	544	37	.	.	.
cord-256444-grw5s2pf	545	1	Subsequently	subsequently	RB
cord-256444-grw5s2pf	545	2	,	,	,
cord-256444-grw5s2pf	545	3	several	several	JJ
cord-256444-grw5s2pf	545	4	additional	additional	JJ
cord-256444-grw5s2pf	545	5	members	member	NNS
cord-256444-grw5s2pf	545	6	of	of	IN
cord-256444-grw5s2pf	545	7	CEA	CEA	NNP
cord-256444-grw5s2pf	545	8	family	family	NN
cord-256444-grw5s2pf	545	9	were	be	VBD
cord-256444-grw5s2pf	545	10	found	find	VBN
cord-256444-grw5s2pf	545	11	to	to	TO
cord-256444-grw5s2pf	545	12	serve	serve	VB
cord-256444-grw5s2pf	545	13	as	as	IN
cord-256444-grw5s2pf	545	14	MHV	MHV	NNP
cord-256444-grw5s2pf	545	15	receptors	receptor	NNS
cord-256444-grw5s2pf	545	16	,	,	,
cord-256444-grw5s2pf	545	17	including	include	VBG
cord-256444-grw5s2pf	545	18	an	an	DT
cord-256444-grw5s2pf	545	19	mmCGM2-like	mmcgm2-like	CD
cord-256444-grw5s2pf	545	20	protein	protein	NN
cord-256444-grw5s2pf	545	21	(	(	-LRB-
cord-256444-grw5s2pf	545	22	also	also	RB
cord-256444-grw5s2pf	545	23	termed	term	VBN
cord-256444-grw5s2pf	545	24	MHVR-2	MHVR-2	NNP
cord-256444-grw5s2pf	545	25	and	and	CC
cord-256444-grw5s2pf	545	26	BgpB	BgpB	NNP
cord-256444-grw5s2pf	545	27	)	)	-RRB-
cord-256444-grw5s2pf	545	28	,	,	,
cord-256444-grw5s2pf	545	29	which	which	WDT
cord-256444-grw5s2pf	545	30	is	be	VBZ
cord-256444-grw5s2pf	545	31	the	the	DT
cord-256444-grw5s2pf	545	32	product	product	NN
cord-256444-grw5s2pf	545	33	of	of	IN
cord-256444-grw5s2pf	545	34	an	an	DT
cord-256444-grw5s2pf	545	35	alternatively	alternatively	RB
cord-256444-grw5s2pf	545	36	spliced	splice	VBN
cord-256444-grw5s2pf	545	37	form	form	NN
cord-256444-grw5s2pf	545	38	of	of	IN
cord-256444-grw5s2pf	545	39	mmCGMl	mmCGMl	NNP
cord-256444-grw5s2pf	545	40	RNA	RNA	NNP
cord-256444-grw5s2pf	545	41	and	and	CC
cord-256444-grw5s2pf	545	42	is	be	VBZ
cord-256444-grw5s2pf	545	43	expressed	express	VBN
cord-256444-grw5s2pf	545	44	in	in	IN
cord-256444-grw5s2pf	545	45	both	both	CC
cord-256444-grw5s2pf	545	46	the	the	DT
cord-256444-grw5s2pf	545	47	liver	liver	NN
cord-256444-grw5s2pf	545	48	and	and	CC
cord-256444-grw5s2pf	545	49	brain	brain	NN
cord-256444-grw5s2pf	545	50	,	,	,
cord-256444-grw5s2pf	545	51	in	in	IN
cord-256444-grw5s2pf	545	52	contrast	contrast	NN
cord-256444-grw5s2pf	545	53	to	to	IN
cord-256444-grw5s2pf	545	54	the	the	DT
cord-256444-grw5s2pf	545	55	liver	liver	NN
cord-256444-grw5s2pf	545	56	-	-	HYPH
cord-256444-grw5s2pf	545	57	specific	specific	JJ
cord-256444-grw5s2pf	545	58	expression	expression	NN
cord-256444-grw5s2pf	545	59	of	of	IN
cord-256444-grw5s2pf	545	60	mmCGMl	mmCGMl	NNP
cord-256444-grw5s2pf	546	1	(	(	-LRB-
cord-256444-grw5s2pf	546	2	Yokomori	Yokomori	NNP
cord-256444-grw5s2pf	546	3	and	and	CC
cord-256444-grw5s2pf	546	4	Dveksler	Dveksler	NNP
cord-256444-grw5s2pf	546	5	et	et	NNP
cord-256444-grw5s2pf	546	6	al	al	NNP
cord-256444-grw5s2pf	546	7	.	.	NNP
cord-256444-grw5s2pf	546	8	,	,	,
cord-256444-grw5s2pf	546	9	1993a	1993a	CD
cord-256444-grw5s2pf	546	10	)	)	-RRB-
cord-256444-grw5s2pf	546	11	;	;	:
cord-256444-grw5s2pf	546	12	an	an	DT
cord-256444-grw5s2pf	546	13	allelic	allelic	JJ
cord-256444-grw5s2pf	546	14	gene	gene	NN
cord-256444-grw5s2pf	546	15	product	product	NN
cord-256444-grw5s2pf	546	16	of	of	IN
cord-256444-grw5s2pf	546	17	the	the	DT
cord-256444-grw5s2pf	546	18	bgp	bgp	NN
cord-256444-grw5s2pf	546	19	gene	gene	NN
cord-256444-grw5s2pf	546	20	in	in	IN
cord-256444-grw5s2pf	546	21	SJL	SJL	NNP
cord-256444-grw5s2pf	546	22	mice	mouse	NNS
cord-256444-grw5s2pf	547	1	,	,	,
cord-256444-grw5s2pf	547	2	a	a	DT
cord-256444-grw5s2pf	547	3	mouse	mouse	NN
cord-256444-grw5s2pf	547	4	strain	strain	NN
cord-256444-grw5s2pf	547	5	resistant	resistant	JJ
cord-256444-grw5s2pf	547	6	to	to	IN
cord-256444-grw5s2pf	547	7	MHV	MHV	NNP
cord-256444-grw5s2pf	547	8	infection	infection	NN
cord-256444-grw5s2pf	548	1	(	(	-LRB-
cord-256444-grw5s2pf	548	2	Yokomori	Yokomori	NNP
cord-256444-grw5s2pf	548	3	and	and	CC
cord-256444-grw5s2pf	548	4	Lai	Lai	NNP
cord-256444-grw5s2pf	548	5	,	,	,
cord-256444-grw5s2pf	548	6	199213	199213	CD
cord-256444-grw5s2pf	548	7	;	;	:
cord-256444-grw5s2pf	548	8	Dveksler	Dveksler	NNP
cord-256444-grw5s2pf	548	9	et	et	NNP
cord-256444-grw5s2pf	548	10	al	al	NNP
cord-256444-grw5s2pf	548	11	.	.	NNP
cord-256444-grw5s2pf	548	12	,	,	,
cord-256444-grw5s2pf	548	13	1993a	1993a	CD
cord-256444-grw5s2pf	548	14	)	)	-RRB-
cord-256444-grw5s2pf	548	15	;	;	:
cord-256444-grw5s2pf	549	1	Bgp-2	Bgp-2	NNP
cord-256444-grw5s2pf	549	2	,	,	,
cord-256444-grw5s2pf	549	3	which	which	WDT
cord-256444-grw5s2pf	549	4	is	be	VBZ
cord-256444-grw5s2pf	549	5	the	the	DT
cord-256444-grw5s2pf	549	6	product	product	NN
cord-256444-grw5s2pf	549	7	of	of	IN
cord-256444-grw5s2pf	549	8	a	a	DT
cord-256444-grw5s2pf	549	9	new	new	JJ
cord-256444-grw5s2pf	549	10	member	member	NN
cord-256444-grw5s2pf	549	11	of	of	IN
cord-256444-grw5s2pf	549	12	the	the	DT
cord-256444-grw5s2pf	549	13	murine	murine	JJ
cord-256444-grw5s2pf	549	14	Bgp	Bgp	NNP
cord-256444-grw5s2pf	549	15	gene	gene	NN
cord-256444-grw5s2pf	549	16	(	(	-LRB-
cord-256444-grw5s2pf	549	17	Nedellec	Nedellec	NNP
cord-256444-grw5s2pf	549	18	et	et	NNP
cord-256444-grw5s2pf	549	19	al	al	NNP
cord-256444-grw5s2pf	549	20	.	.	NNP
cord-256444-grw5s2pf	549	21	,	,	,
cord-256444-grw5s2pf	549	22	1994	1994	CD
cord-256444-grw5s2pf	549	23	)	)	-RRB-
cord-256444-grw5s2pf	549	24	;	;	:
cord-256444-grw5s2pf	549	25	and	and	CC
cord-256444-grw5s2pf	549	26	a	a	DT
cord-256444-grw5s2pf	549	27	novel	novel	JJ
cord-256444-grw5s2pf	549	28	pregnancy	pregnancy	NN
cord-256444-grw5s2pf	549	29	-	-	HYPH
cord-256444-grw5s2pf	549	30	specific	specific	JJ
cord-256444-grw5s2pf	549	31	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	549	32	(	(	-LRB-
cord-256444-grw5s2pf	549	33	psg)-like	psg)-like	IN
cord-256444-grw5s2pf	549	34	protein	protein	NN
cord-256444-grw5s2pf	549	35	,	,	,
cord-256444-grw5s2pf	549	36	which	which	WDT
cord-256444-grw5s2pf	549	37	is	be	VBZ
cord-256444-grw5s2pf	549	38	expressed	express	VBN
cord-256444-grw5s2pf	549	39	in	in	IN
cord-256444-grw5s2pf	549	40	the	the	DT
cord-256444-grw5s2pf	549	41	mouse	mouse	NN
cord-256444-grw5s2pf	549	42	brain	brain	NN
cord-256444-grw5s2pf	549	43	,	,	,
cord-256444-grw5s2pf	549	44	in	in	IN
cord-256444-grw5s2pf	549	45	contrast	contrast	NN
cord-256444-grw5s2pf	549	46	to	to	IN
cord-256444-grw5s2pf	549	47	placenta	placenta	NN
cord-256444-grw5s2pf	549	48	-	-	HYPH
cord-256444-grw5s2pf	549	49	specific	specific	JJ
cord-256444-grw5s2pf	549	50	expression	expression	NN
cord-256444-grw5s2pf	549	51	of	of	IN
cord-256444-grw5s2pf	549	52	other	other	JJ
cord-256444-grw5s2pf	549	53	psg	psg	NNP
cord-256444-grw5s2pf	549	54	molecules	molecule	NNS
cord-256444-grw5s2pf	549	55	.	.	.
cord-256444-grw5s2pf	550	1	All	all	PDT
cord-256444-grw5s2pf	550	2	these	these	DT
cord-256444-grw5s2pf	550	3	molecules	molecule	NNS
cord-256444-grw5s2pf	550	4	contain	contain	VBP
cord-256444-grw5s2pf	550	5	a	a	DT
cord-256444-grw5s2pf	550	6	consensus	consensus	NN
cord-256444-grw5s2pf	550	7	motif	motif	NN
cord-256444-grw5s2pf	550	8	in	in	IN
cord-256444-grw5s2pf	550	9	the	the	DT
cord-256444-grw5s2pf	550	10	virus	virus	NN
cord-256444-grw5s2pf	550	11	-	-	HYPH
cord-256444-grw5s2pf	550	12	binding	bind	VBG
cord-256444-grw5s2pf	550	13	domain	domain	NN
cord-256444-grw5s2pf	550	14	(	(	-LRB-
cord-256444-grw5s2pf	550	15	N	n	CD
cord-256444-grw5s2pf	550	16	-	-	HYPH
cord-256444-grw5s2pf	550	17	terminal	terminal	NN
cord-256444-grw5s2pf	550	18	loop	loop	NN
cord-256444-grw5s2pf	550	19	)	)	-RRB-
cord-256444-grw5s2pf	550	20	.	.	.
cord-256444-grw5s2pf	551	1	Thus	thus	RB
cord-256444-grw5s2pf	551	2	,	,	,
cord-256444-grw5s2pf	551	3	several	several	JJ
cord-256444-grw5s2pf	551	4	different	different	JJ
cord-256444-grw5s2pf	551	5	CEA	CEA	NNP
cord-256444-grw5s2pf	551	6	family	family	NN
cord-256444-grw5s2pf	551	7	members	member	NNS
cord-256444-grw5s2pf	551	8	,	,	,
cord-256444-grw5s2pf	551	9	which	which	WDT
cord-256444-grw5s2pf	551	10	are	be	VBP
cord-256444-grw5s2pf	551	11	differentially	differentially	RB
cord-256444-grw5s2pf	551	12	expressed	express	VBN
cord-256444-grw5s2pf	551	13	in	in	IN
cord-256444-grw5s2pf	551	14	different	different	JJ
cord-256444-grw5s2pf	551	15	cells	cell	NNS
cord-256444-grw5s2pf	551	16	and	and	CC
cord-256444-grw5s2pf	551	17	tissues	tissue	NNS
cord-256444-grw5s2pf	551	18	,	,	,
cord-256444-grw5s2pf	551	19	can	can	MD
cord-256444-grw5s2pf	551	20	potentially	potentially	RB
cord-256444-grw5s2pf	551	21	serve	serve	VB
cord-256444-grw5s2pf	551	22	as	as	IN
cord-256444-grw5s2pf	551	23	an	an	DT
cord-256444-grw5s2pf	551	24	MHV	MHV	NNP
cord-256444-grw5s2pf	551	25	receptor	receptor	NN
cord-256444-grw5s2pf	551	26	.	.	.
cord-256444-grw5s2pf	552	1	Different	different	JJ
cord-256444-grw5s2pf	552	2	strains	strain	NNS
cord-256444-grw5s2pf	552	3	of	of	IN
cord-256444-grw5s2pf	552	4	MHV	MHV	NNP
cord-256444-grw5s2pf	552	5	may	may	MD
cord-256444-grw5s2pf	552	6	use	use	VB
cord-256444-grw5s2pf	552	7	different	different	JJ
cord-256444-grw5s2pf	552	8	CEArelated	cearelate	VBN
cord-256444-grw5s2pf	552	9	molecules	molecule	NNS
cord-256444-grw5s2pf	552	10	as	as	IN
cord-256444-grw5s2pf	552	11	receptors	receptor	NNS
cord-256444-grw5s2pf	552	12	at	at	IN
cord-256444-grw5s2pf	552	13	different	different	JJ
cord-256444-grw5s2pf	552	14	efficiencies	efficiency	NNS
cord-256444-grw5s2pf	552	15	(	(	-LRB-
cord-256444-grw5s2pf	552	16	Compton	Compton	NNP
cord-256444-grw5s2pf	552	17	,	,	,
cord-256444-grw5s2pf	552	18	1994	1994	CD
cord-256444-grw5s2pf	552	19	;	;	:
cord-256444-grw5s2pf	552	20	.	.	.
cord-256444-grw5s2pf	553	1	The	the	DT
cord-256444-grw5s2pf	553	2	prototype	prototype	NN
cord-256444-grw5s2pf	553	3	MHV	mhv	NN
cord-256444-grw5s2pf	553	4	receptors	receptor	NNS
cord-256444-grw5s2pf	553	5	(	(	-LRB-
cord-256444-grw5s2pf	553	6	MHVR-1	MHVR-1	NNS
cord-256444-grw5s2pf	553	7	)	)	-RRB-
cord-256444-grw5s2pf	553	8	are	be	VBP
cord-256444-grw5s2pf	553	9	expressed	express	VBN
cord-256444-grw5s2pf	553	10	in	in	IN
cord-256444-grw5s2pf	553	11	the	the	DT
cord-256444-grw5s2pf	553	12	liver	liver	NN
cord-256444-grw5s2pf	553	13	,	,	,
cord-256444-grw5s2pf	553	14	gastrointestinal	gastrointestinal	JJ
cord-256444-grw5s2pf	553	15	tract	tract	NN
cord-256444-grw5s2pf	553	16	,	,	,
cord-256444-grw5s2pf	553	17	B	b	NN
cord-256444-grw5s2pf	553	18	cells	cell	NNS
cord-256444-grw5s2pf	553	19	,	,	,
cord-256444-grw5s2pf	553	20	macrophages	macrophage	NNS
cord-256444-grw5s2pf	553	21	,	,	,
cord-256444-grw5s2pf	553	22	and	and	CC
cord-256444-grw5s2pf	553	23	endothelial	endothelial	JJ
cord-256444-grw5s2pf	553	24	cells	cell	NNS
cord-256444-grw5s2pf	553	25	but	but	CC
cord-256444-grw5s2pf	553	26	not	not	RB
cord-256444-grw5s2pf	553	27	in	in	IN
cord-256444-grw5s2pf	553	28	T	T	NNP
cord-256444-grw5s2pf	553	29	cells	cell	NNS
cord-256444-grw5s2pf	553	30	(	(	-LRB-
cord-256444-grw5s2pf	554	1	Coutelier	Coutelier	NNP
cord-256444-grw5s2pf	554	2	et	et	NNP
cord-256444-grw5s2pf	554	3	al	al	NNP
cord-256444-grw5s2pf	554	4	.	.	.
cord-256444-grw5s2pf	555	1	,	,	,
cord-256444-grw5s2pf	555	2	1994	1994	CD
cord-256444-grw5s2pf	555	3	;	;	:
cord-256444-grw5s2pf	555	4	Godfraind	Godfraind	NNP
cord-256444-grw5s2pf	555	5	et	et	NNP
cord-256444-grw5s2pf	555	6	al	al	NNP
cord-256444-grw5s2pf	555	7	.	.	NNP
cord-256444-grw5s2pf	555	8	,	,	,
cord-256444-grw5s2pf	555	9	1995	1995	CD
cord-256444-grw5s2pf	555	10	)	)	-RRB-
cord-256444-grw5s2pf	555	11	,	,	,
cord-256444-grw5s2pf	555	12	consistent	consistent	JJ
cord-256444-grw5s2pf	555	13	with	with	IN
cord-256444-grw5s2pf	555	14	the	the	DT
cord-256444-grw5s2pf	555	15	target	target	NN
cord-256444-grw5s2pf	555	16	cell	cell	NN
cord-256444-grw5s2pf	555	17	specificity	specificity	NN
cord-256444-grw5s2pf	555	18	of	of	IN
cord-256444-grw5s2pf	555	19	MHV	MHV	NNP
cord-256444-grw5s2pf	555	20	.	.	.
cord-256444-grw5s2pf	556	1	However	however	RB
cord-256444-grw5s2pf	556	2	,	,	,
cord-256444-grw5s2pf	556	3	the	the	DT
cord-256444-grw5s2pf	556	4	MHV	MHV	NNP
cord-256444-grw5s2pf	556	5	receptor	receptor	NN
cord-256444-grw5s2pf	556	6	is	be	VBZ
cord-256444-grw5s2pf	556	7	also	also	RB
cord-256444-grw5s2pf	556	8	expressed	express	VBN
cord-256444-grw5s2pf	556	9	in	in	IN
cord-256444-grw5s2pf	556	10	other	other	JJ
cord-256444-grw5s2pf	556	11	tissues	tissue	NNS
cord-256444-grw5s2pf	556	12	,	,	,
cord-256444-grw5s2pf	556	13	e.g.	e.g.	RB
cord-256444-grw5s2pf	556	14	,	,	,
cord-256444-grw5s2pf	556	15	kidney	kidney	NN
cord-256444-grw5s2pf	556	16	,	,	,
cord-256444-grw5s2pf	556	17	which	which	WDT
cord-256444-grw5s2pf	556	18	are	be	VBP
cord-256444-grw5s2pf	556	19	not	not	RB
cord-256444-grw5s2pf	556	20	targets	target	NNS
cord-256444-grw5s2pf	556	21	for	for	IN
cord-256444-grw5s2pf	556	22	MHV	MHV	NNP
cord-256444-grw5s2pf	556	23	infection	infection	NN
cord-256444-grw5s2pf	556	24	.	.	.
cord-256444-grw5s2pf	557	1	Also	also	RB
cord-256444-grw5s2pf	557	2	,	,	,
cord-256444-grw5s2pf	557	3	SJL	SJL	NNP
cord-256444-grw5s2pf	557	4	mice	mouse	NNS
cord-256444-grw5s2pf	557	5	express	express	VBP
cord-256444-grw5s2pf	557	6	a	a	DT
cord-256444-grw5s2pf	557	7	functional	functional	JJ
cord-256444-grw5s2pf	557	8	MHV	MHV	NNP
cord-256444-grw5s2pf	557	9	receptor	receptor	NN
cord-256444-grw5s2pf	557	10	(	(	-LRB-
cord-256444-grw5s2pf	557	11	Yokomori	Yokomori	NNP
cord-256444-grw5s2pf	557	12	and	and	CC
cord-256444-grw5s2pf	557	13	Lai	Lai	NNP
cord-256444-grw5s2pf	557	14	,	,	,
cord-256444-grw5s2pf	557	15	199213	199213	CD
cord-256444-grw5s2pf	557	16	;	;	:
cord-256444-grw5s2pf	557	17	Dveksler	Dveksler	NNP
cord-256444-grw5s2pf	557	18	et	et	NNP
cord-256444-grw5s2pf	557	19	al	al	NNP
cord-256444-grw5s2pf	557	20	.	.	NNP
cord-256444-grw5s2pf	557	21	,	,	,
cord-256444-grw5s2pf	557	22	1993a	1993a	CD
cord-256444-grw5s2pf	557	23	)	)	-RRB-
cord-256444-grw5s2pf	557	24	but	but	CC
cord-256444-grw5s2pf	557	25	are	be	VBP
cord-256444-grw5s2pf	557	26	resistant	resistant	JJ
cord-256444-grw5s2pf	557	27	to	to	IN
cord-256444-grw5s2pf	557	28	MHV	MHV	NNP
cord-256444-grw5s2pf	557	29	infection	infection	NN
cord-256444-grw5s2pf	558	1	(	(	-LRB-
cord-256444-grw5s2pf	558	2	Knobler	Knobler	NNP
cord-256444-grw5s2pf	558	3	et	et	NNP
cord-256444-grw5s2pf	558	4	al	al	NNP
cord-256444-grw5s2pf	558	5	.	.	NNP
cord-256444-grw5s2pf	558	6	,	,	,
cord-256444-grw5s2pf	558	7	1984	1984	CD
cord-256444-grw5s2pf	558	8	)	)	-RRB-
cord-256444-grw5s2pf	558	9	.	.	.
cord-256444-grw5s2pf	559	1	Thus	thus	RB
cord-256444-grw5s2pf	559	2	,	,	,
cord-256444-grw5s2pf	559	3	receptor	receptor	NN
cord-256444-grw5s2pf	559	4	expression	expression	NN
cord-256444-grw5s2pf	559	5	is	be	VBZ
cord-256444-grw5s2pf	559	6	not	not	RB
cord-256444-grw5s2pf	559	7	sufficient	sufficient	JJ
cord-256444-grw5s2pf	559	8	for	for	IN
cord-256444-grw5s2pf	559	9	viral	viral	JJ
cord-256444-grw5s2pf	559	10	infection	infection	NN
cord-256444-grw5s2pf	559	11	.	.	.
cord-256444-grw5s2pf	560	1	It	-PRON-	PRP
cord-256444-grw5s2pf	560	2	is	be	VBZ
cord-256444-grw5s2pf	560	3	not	not	RB
cord-256444-grw5s2pf	560	4	yet	yet	RB
cord-256444-grw5s2pf	560	5	clear	clear	JJ
cord-256444-grw5s2pf	560	6	which	which	WDT
cord-256444-grw5s2pf	560	7	molecules	molecule	NNS
cord-256444-grw5s2pf	560	8	are	be	VBP
cord-256444-grw5s2pf	560	9	used	use	VBN
cord-256444-grw5s2pf	560	10	by	by	IN
cord-256444-grw5s2pf	560	11	MHV	MHV	NNP
cord-256444-grw5s2pf	560	12	as	as	IN
cord-256444-grw5s2pf	560	13	receptors	receptor	NNS
cord-256444-grw5s2pf	560	14	in	in	IN
cord-256444-grw5s2pf	560	15	cross	cross	JJ
cord-256444-grw5s2pf	560	16	-	-	JJ
cord-256444-grw5s2pf	560	17	species	species	JJ
cord-256444-grw5s2pf	560	18	infection	infection	NN
cord-256444-grw5s2pf	561	1	(	(	-LRB-
cord-256444-grw5s2pf	561	2	e.g.	e.g.	RB
cord-256444-grw5s2pf	561	3	,	,	,
cord-256444-grw5s2pf	561	4	rats	rat	NNS
cord-256444-grw5s2pf	561	5	and	and	CC
cord-256444-grw5s2pf	561	6	monkeys	monkey	NNS
cord-256444-grw5s2pf	561	7	)	)	-RRB-
cord-256444-grw5s2pf	562	1	(	(	-LRB-
cord-256444-grw5s2pf	562	2	Murray	Murray	NNP
cord-256444-grw5s2pf	562	3	et	et	NNP
cord-256444-grw5s2pf	562	4	al	al	NNP
cord-256444-grw5s2pf	562	5	.	.	NNP
cord-256444-grw5s2pf	562	6	,	,	,
cord-256444-grw5s2pf	562	7	1992	1992	CD
cord-256444-grw5s2pf	562	8	;	;	:
cord-256444-grw5s2pf	562	9	Cabirac	Cabirac	NNP
cord-256444-grw5s2pf	562	10	et	et	NNP
cord-256444-grw5s2pf	562	11	al	al	NNP
cord-256444-grw5s2pf	562	12	.	.	NNP
cord-256444-grw5s2pf	562	13	,	,	,
cord-256444-grw5s2pf	562	14	1994	1994	CD
cord-256444-grw5s2pf	562	15	)	)	-RRB-
cord-256444-grw5s2pf	562	16	.	.	.
cord-256444-grw5s2pf	563	1	Recently	recently	RB
cord-256444-grw5s2pf	563	2	it	-PRON-	PRP
cord-256444-grw5s2pf	563	3	was	be	VBD
cord-256444-grw5s2pf	563	4	shown	show	VBN
cord-256444-grw5s2pf	563	5	that	that	IN
cord-256444-grw5s2pf	563	6	bgp	bgp	NN
cord-256444-grw5s2pf	563	7	and	and	CC
cord-256444-grw5s2pf	563	8	CEA	CEA	NNP
cord-256444-grw5s2pf	563	9	molecules	molecule	NNS
cord-256444-grw5s2pf	563	10	of	of	IN
cord-256444-grw5s2pf	563	11	human	human	JJ
cord-256444-grw5s2pf	563	12	origin	origin	NN
cord-256444-grw5s2pf	563	13	could	could	MD
cord-256444-grw5s2pf	563	14	serve	serve	VB
cord-256444-grw5s2pf	563	15	as	as	IN
cord-256444-grw5s2pf	563	16	receptors	receptor	NNS
cord-256444-grw5s2pf	563	17	for	for	IN
cord-256444-grw5s2pf	563	18	some	some	DT
cord-256444-grw5s2pf	563	19	MHV	MHV	NNP
cord-256444-grw5s2pf	563	20	strains	strain	NNS
cord-256444-grw5s2pf	563	21	.	.	.
cord-256444-grw5s2pf	564	1	The	the	DT
cord-256444-grw5s2pf	564	2	expression	expression	NN
cord-256444-grw5s2pf	564	3	of	of	IN
cord-256444-grw5s2pf	564	4	the	the	DT
cord-256444-grw5s2pf	564	5	receptor	receptor	NN
cord-256444-grw5s2pf	564	6	molecules	molecule	NNS
cord-256444-grw5s2pf	564	7	on	on	IN
cord-256444-grw5s2pf	564	8	the	the	DT
cord-256444-grw5s2pf	564	9	cell	cell	NN
cord-256444-grw5s2pf	564	10	surface	surface	NN
cord-256444-grw5s2pf	564	11	is	be	VBZ
cord-256444-grw5s2pf	564	12	necessary	necessary	JJ
cord-256444-grw5s2pf	564	13	for	for	IN
cord-256444-grw5s2pf	564	14	virus	virus	NN
cord-256444-grw5s2pf	564	15	infection	infection	NN
cord-256444-grw5s2pf	564	16	,	,	,
cord-256444-grw5s2pf	564	17	and	and	CC
cord-256444-grw5s2pf	564	18	the	the	DT
cord-256444-grw5s2pf	564	19	expression	expression	NN
cord-256444-grw5s2pf	564	20	level	level	NN
cord-256444-grw5s2pf	564	21	of	of	IN
cord-256444-grw5s2pf	564	22	the	the	DT
cord-256444-grw5s2pf	564	23	receptor	receptor	NN
cord-256444-grw5s2pf	564	24	may	may	MD
cord-256444-grw5s2pf	564	25	determine	determine	VB
cord-256444-grw5s2pf	564	26	the	the	DT
cord-256444-grw5s2pf	564	27	relative	relative	JJ
cord-256444-grw5s2pf	564	28	susceptibility	susceptibility	NN
cord-256444-grw5s2pf	564	29	or	or	CC
cord-256444-grw5s2pf	564	30	resistance	resistance	NN
cord-256444-grw5s2pf	564	31	to	to	IN
cord-256444-grw5s2pf	564	32	viral	viral	JJ
cord-256444-grw5s2pf	564	33	infection	infection	NN
cord-256444-grw5s2pf	564	34	in	in	IN
cord-256444-grw5s2pf	564	35	some	some	DT
cord-256444-grw5s2pf	564	36	cells	cell	NNS
cord-256444-grw5s2pf	564	37	.	.	.
cord-256444-grw5s2pf	565	1	During	during	IN
cord-256444-grw5s2pf	565	2	persistent	persistent	JJ
cord-256444-grw5s2pf	565	3	viral	viral	JJ
cord-256444-grw5s2pf	565	4	infection	infection	NN
cord-256444-grw5s2pf	565	5	of	of	IN
cord-256444-grw5s2pf	565	6	cultured	cultured	JJ
cord-256444-grw5s2pf	565	7	murine	murine	JJ
cord-256444-grw5s2pf	565	8	cells	cell	NNS
cord-256444-grw5s2pf	565	9	,	,	,
cord-256444-grw5s2pf	565	10	the	the	DT
cord-256444-grw5s2pf	565	11	expression	expression	NN
cord-256444-grw5s2pf	565	12	level	level	NN
cord-256444-grw5s2pf	565	13	of	of	IN
cord-256444-grw5s2pf	565	14	the	the	DT
cord-256444-grw5s2pf	565	15	receptor	receptor	NN
cord-256444-grw5s2pf	565	16	is	be	VBZ
cord-256444-grw5s2pf	565	17	offen	offen	NNP
cord-256444-grw5s2pf	565	18	reduced	reduce	VBN
cord-256444-grw5s2pf	565	19	,	,	,
cord-256444-grw5s2pf	565	20	resulting	result	VBG
cord-256444-grw5s2pf	565	21	in	in	IN
cord-256444-grw5s2pf	565	22	the	the	DT
cord-256444-grw5s2pf	565	23	relative	relative	JJ
cord-256444-grw5s2pf	565	24	resistance	resistance	NN
cord-256444-grw5s2pf	565	25	of	of	IN
cord-256444-grw5s2pf	565	26	the	the	DT
cord-256444-grw5s2pf	565	27	cells	cell	NNS
cord-256444-grw5s2pf	565	28	to	to	IN
cord-256444-grw5s2pf	565	29	viral	viral	JJ
cord-256444-grw5s2pf	565	30	superinfection	superinfection	NN
cord-256444-grw5s2pf	565	31	,	,	,
cord-256444-grw5s2pf	565	32	which	which	WDT
cord-256444-grw5s2pf	565	33	could	could	MD
cord-256444-grw5s2pf	565	34	be	be	VB
cord-256444-grw5s2pf	565	35	overcome	overcome	VBN
cord-256444-grw5s2pf	565	36	by	by	IN
cord-256444-grw5s2pf	565	37	the	the	DT
cord-256444-grw5s2pf	565	38	expression	expression	NN
cord-256444-grw5s2pf	565	39	of	of	IN
cord-256444-grw5s2pf	565	40	an	an	DT
cord-256444-grw5s2pf	565	41	exogenous	exogenous	JJ
cord-256444-grw5s2pf	565	42	receptor	receptor	NN
cord-256444-grw5s2pf	565	43	(	(	-LRB-
cord-256444-grw5s2pf	565	44	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	565	45	et	et	NNP
cord-256444-grw5s2pf	565	46	al	al	NNP
cord-256444-grw5s2pf	565	47	.	.	NNP
cord-256444-grw5s2pf	565	48	,	,	,
cord-256444-grw5s2pf	565	49	1995	1995	CD
cord-256444-grw5s2pf	565	50	;	;	:
cord-256444-grw5s2pf	566	1	Chen	Chen	NNP
cord-256444-grw5s2pf	566	2	and	and	CC
cord-256444-grw5s2pf	566	3	Baric	Baric	NNP
cord-256444-grw5s2pf	566	4	,	,	,
cord-256444-grw5s2pf	566	5	1996	1996	CD
cord-256444-grw5s2pf	566	6	)	)	-RRB-
cord-256444-grw5s2pf	566	7	.	.	.
cord-256444-grw5s2pf	567	1	Thus	thus	RB
cord-256444-grw5s2pf	567	2	,	,	,
cord-256444-grw5s2pf	567	3	there	there	EX
cord-256444-grw5s2pf	567	4	is	be	VBZ
cord-256444-grw5s2pf	567	5	a	a	DT
cord-256444-grw5s2pf	567	6	rough	rough	JJ
cord-256444-grw5s2pf	567	7	correlation	correlation	NN
cord-256444-grw5s2pf	567	8	between	between	IN
cord-256444-grw5s2pf	567	9	receptor	receptor	NN
cord-256444-grw5s2pf	567	10	expression	expression	NN
cord-256444-grw5s2pf	567	11	and	and	CC
cord-256444-grw5s2pf	567	12	the	the	DT
cord-256444-grw5s2pf	567	13	susceptibility	susceptibility	NN
cord-256444-grw5s2pf	567	14	of	of	IN
cord-256444-grw5s2pf	567	15	a	a	DT
cord-256444-grw5s2pf	567	16	cell	cell	NN
cord-256444-grw5s2pf	567	17	type	type	NN
cord-256444-grw5s2pf	567	18	to	to	IN
cord-256444-grw5s2pf	567	19	virus	virus	NN
cord-256444-grw5s2pf	567	20	infection	infection	NN
cord-256444-grw5s2pf	567	21	.	.	.
cord-256444-grw5s2pf	568	1	Under	under	IN
cord-256444-grw5s2pf	568	2	certain	certain	JJ
cord-256444-grw5s2pf	568	3	circumstances	circumstance	NNS
cord-256444-grw5s2pf	568	4	,	,	,
cord-256444-grw5s2pf	568	5	virus	virus	NN
cord-256444-grw5s2pf	568	6	may	may	MD
cord-256444-grw5s2pf	568	7	infect	infect	VB
cord-256444-grw5s2pf	568	8	cells	cell	NNS
cord-256444-grw5s2pf	568	9	by	by	IN
cord-256444-grw5s2pf	568	10	a	a	DT
cord-256444-grw5s2pf	568	11	receptorindependent	receptorindependent	NN
cord-256444-grw5s2pf	568	12	mechanism	mechanism	NN
cord-256444-grw5s2pf	568	13	;	;	:
cord-256444-grw5s2pf	568	14	for	for	IN
cord-256444-grw5s2pf	568	15	example	example	NN
cord-256444-grw5s2pf	568	16	,	,	,
cord-256444-grw5s2pf	568	17	MHV	MHV	NNP
cord-256444-grw5s2pf	568	18	-	-	HYPH
cord-256444-grw5s2pf	568	19	infected	infect	VBN
cord-256444-grw5s2pf	568	20	murine	murine	JJ
cord-256444-grw5s2pf	568	21	cells	cell	NNS
cord-256444-grw5s2pf	568	22	may	may	MD
cord-256444-grw5s2pf	568	23	fuse	fuse	VB
cord-256444-grw5s2pf	568	24	with	with	IN
cord-256444-grw5s2pf	568	25	human	human	JJ
cord-256444-grw5s2pf	568	26	cells	cell	NNS
cord-256444-grw5s2pf	568	27	,	,	,
cord-256444-grw5s2pf	568	28	which	which	WDT
cord-256444-grw5s2pf	568	29	do	do	VBP
cord-256444-grw5s2pf	568	30	not	not	RB
cord-256444-grw5s2pf	568	31	have	have	VB
cord-256444-grw5s2pf	568	32	MHV	MHV	NNP
cord-256444-grw5s2pf	568	33	receptors	receptor	NNS
cord-256444-grw5s2pf	568	34	,	,	,
cord-256444-grw5s2pf	568	35	and	and	CC
cord-256444-grw5s2pf	568	36	cause	cause	VB
cord-256444-grw5s2pf	568	37	the	the	DT
cord-256444-grw5s2pf	568	38	latter	latter	JJ
cord-256444-grw5s2pf	568	39	cells	cell	NNS
cord-256444-grw5s2pf	568	40	to	to	TO
cord-256444-grw5s2pf	568	41	become	become	VB
cord-256444-grw5s2pf	568	42	infected	infect	VBN
cord-256444-grw5s2pf	569	1	(	(	-LRB-
cord-256444-grw5s2pf	569	2	Gallagher	Gallagher	NNP
cord-256444-grw5s2pf	569	3	et	et	NNP
cord-256444-grw5s2pf	569	4	al	al	NNP
cord-256444-grw5s2pf	569	5	.	.	NNP
cord-256444-grw5s2pf	569	6	,	,	,
cord-256444-grw5s2pf	569	7	1992	1992	CD
cord-256444-grw5s2pf	569	8	)	)	-RRB-
cord-256444-grw5s2pf	569	9	.	.	.
cord-256444-grw5s2pf	570	1	It	-PRON-	PRP
cord-256444-grw5s2pf	570	2	has	have	VBZ
cord-256444-grw5s2pf	570	3	been	be	VBN
cord-256444-grw5s2pf	570	4	shown	show	VBN
cord-256444-grw5s2pf	570	5	that	that	IN
cord-256444-grw5s2pf	570	6	MHV	MHV	NNP
cord-256444-grw5s2pf	570	7	infects	infect	VBZ
cord-256444-grw5s2pf	570	8	polarized	polarized	JJ
cord-256444-grw5s2pf	570	9	epithelial	epithelial	JJ
cord-256444-grw5s2pf	570	10	cells	cell	NNS
cord-256444-grw5s2pf	570	11	through	through	IN
cord-256444-grw5s2pf	570	12	the	the	DT
cord-256444-grw5s2pf	570	13	apical	apical	JJ
cord-256444-grw5s2pf	570	14	,	,	,
cord-256444-grw5s2pf	570	15	but	but	CC
cord-256444-grw5s2pf	570	16	not	not	RB
cord-256444-grw5s2pf	570	17	the	the	DT
cord-256444-grw5s2pf	570	18	basolateral	basolateral	JJ
cord-256444-grw5s2pf	570	19	,	,	,
cord-256444-grw5s2pf	570	20	surface	surface	NN
cord-256444-grw5s2pf	571	1	(	(	-LRB-
cord-256444-grw5s2pf	571	2	Rossen	Rossen	NNP
cord-256444-grw5s2pf	571	3	et	et	NNP
cord-256444-grw5s2pf	571	4	al	al	NNP
cord-256444-grw5s2pf	571	5	.	.	NNP
cord-256444-grw5s2pf	571	6	,	,	,
cord-256444-grw5s2pf	572	1	1995a	1995a	CD
cord-256444-grw5s2pf	573	1	(	(	-LRB-
cord-256444-grw5s2pf	573	2	Rossen	Rossen	NNP
cord-256444-grw5s2pf	573	3	et	et	NNP
cord-256444-grw5s2pf	573	4	al	al	NNP
cord-256444-grw5s2pf	573	5	.	.	NNP
cord-256444-grw5s2pf	573	6	,	,	,
cord-256444-grw5s2pf	573	7	,	,	,
cord-256444-grw5s2pf	573	8	1997	1997	CD
cord-256444-grw5s2pf	573	9	.	.	.
cord-256444-grw5s2pf	574	1	It	-PRON-	PRP
cord-256444-grw5s2pf	574	2	is	be	VBZ
cord-256444-grw5s2pf	574	3	not	not	RB
cord-256444-grw5s2pf	574	4	clear	clear	JJ
cord-256444-grw5s2pf	574	5	whether	whether	IN
cord-256444-grw5s2pf	574	6	the	the	DT
cord-256444-grw5s2pf	574	7	virus	virus	NN
cord-256444-grw5s2pf	574	8	receptor	receptor	NN
cord-256444-grw5s2pf	574	9	is	be	VBZ
cord-256444-grw5s2pf	574	10	differentially	differentially	RB
cord-256444-grw5s2pf	574	11	expressed	express	VBN
cord-256444-grw5s2pf	574	12	on	on	IN
cord-256444-grw5s2pf	574	13	the	the	DT
cord-256444-grw5s2pf	574	14	two	two	CD
cord-256444-grw5s2pf	574	15	different	different	JJ
cord-256444-grw5s2pf	574	16	surfaces	surface	NNS
cord-256444-grw5s2pf	574	17	.	.	.
cord-256444-grw5s2pf	575	1	b.	b.	NNP
cord-256444-grw5s2pf	575	2	Receptors	Receptors	NNP
cord-256444-grw5s2pf	575	3	for	for	IN
cord-256444-grw5s2pf	575	4	TGEVand	tgevand	NN
cord-256444-grw5s2pf	575	5	HCV-229E.	hcv-229e.	NN
cord-256444-grw5s2pf	576	1	The	the	DT
cord-256444-grw5s2pf	576	2	receptors	receptor	NNS
cord-256444-grw5s2pf	576	3	for	for	IN
cord-256444-grw5s2pf	576	4	TGEV	TGEV	NNP
cord-256444-grw5s2pf	576	5	and	and	CC
cord-256444-grw5s2pf	576	6	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	576	7	have	have	VBP
cord-256444-grw5s2pf	576	8	been	be	VBN
cord-256444-grw5s2pf	576	9	identified	identify	VBN
cord-256444-grw5s2pf	576	10	as	as	IN
cord-256444-grw5s2pf	576	11	aminopeptidase	aminopeptidase	NN
cord-256444-grw5s2pf	576	12	N	N	NNP
cord-256444-grw5s2pf	576	13	(	(	-LRB-
cord-256444-grw5s2pf	576	14	APN	APN	NNP
cord-256444-grw5s2pf	576	15	)	)	-RRB-
cord-256444-grw5s2pf	576	16	of	of	IN
cord-256444-grw5s2pf	576	17	the	the	DT
cord-256444-grw5s2pf	576	18	porcine	porcine	JJ
cord-256444-grw5s2pf	576	19	and	and	CC
cord-256444-grw5s2pf	576	20	human	human	JJ
cord-256444-grw5s2pf	576	21	species	specie	NNS
cord-256444-grw5s2pf	576	22	,	,	,
cord-256444-grw5s2pf	577	1	respectively	respectively	RB
cord-256444-grw5s2pf	577	2	(	(	-LRB-
cord-256444-grw5s2pf	577	3	Delmas	Delmas	NNP
cord-256444-grw5s2pf	577	4	et	et	FW
cord-256444-grw5s2pf	577	5	al	al	NNP
cord-256444-grw5s2pf	577	6	.	.	NNP
cord-256444-grw5s2pf	577	7	,	,	,
cord-256444-grw5s2pf	577	8	1992	1992	CD
cord-256444-grw5s2pf	577	9	;	;	:
cord-256444-grw5s2pf	577	10	Yeager	Yeager	NNP
cord-256444-grw5s2pf	577	11	et	et	NNP
cord-256444-grw5s2pf	577	12	al	al	NNP
cord-256444-grw5s2pf	577	13	.	.	NNP
cord-256444-grw5s2pf	577	14	,	,	,
cord-256444-grw5s2pf	577	15	1992	1992	CD
cord-256444-grw5s2pf	577	16	)	)	-RRB-
cord-256444-grw5s2pf	577	17	.	.	.
cord-256444-grw5s2pf	578	1	PRCV	PRCV	NNP
cord-256444-grw5s2pf	578	2	also	also	RB
cord-256444-grw5s2pf	578	3	uses	use	VBZ
cord-256444-grw5s2pf	578	4	porcine	porcine	JJ
cord-256444-grw5s2pf	578	5	APN	APN	NNP
cord-256444-grw5s2pf	578	6	as	as	IN
cord-256444-grw5s2pf	578	7	a	a	DT
cord-256444-grw5s2pf	578	8	receptor	receptor	NN
cord-256444-grw5s2pf	578	9	;	;	:
cord-256444-grw5s2pf	578	10	thus	thus	RB
cord-256444-grw5s2pf	578	11	,	,	,
cord-256444-grw5s2pf	578	12	virus	virus	NN
cord-256444-grw5s2pf	578	13	binding	bind	VBG
cord-256444-grw5s2pf	578	14	to	to	IN
cord-256444-grw5s2pf	578	15	the	the	DT
cord-256444-grw5s2pf	578	16	receptor	receptor	NN
cord-256444-grw5s2pf	578	17	is	be	VBZ
cord-256444-grw5s2pf	578	18	not	not	RB
cord-256444-grw5s2pf	578	19	sufficient	sufficient	JJ
cord-256444-grw5s2pf	578	20	to	to	TO
cord-256444-grw5s2pf	578	21	explain	explain	VB
cord-256444-grw5s2pf	578	22	the	the	DT
cord-256444-grw5s2pf	578	23	differences	difference	NNS
cord-256444-grw5s2pf	578	24	in	in	IN
cord-256444-grw5s2pf	578	25	tissue	tissue	NN
cord-256444-grw5s2pf	578	26	tropism	tropism	NN
cord-256444-grw5s2pf	578	27	between	between	IN
cord-256444-grw5s2pf	578	28	TGEV	TGEV	NNP
cord-256444-grw5s2pf	578	29	and	and	CC
cord-256444-grw5s2pf	578	30	PRCV	PRCV	NNP
cord-256444-grw5s2pf	578	31	.	.	.
cord-256444-grw5s2pf	579	1	APN	APN	NNP
cord-256444-grw5s2pf	579	2	is	be	VBZ
cord-256444-grw5s2pf	579	3	a	a	DT
cord-256444-grw5s2pf	579	4	member	member	NN
cord-256444-grw5s2pf	579	5	of	of	IN
cord-256444-grw5s2pf	579	6	the	the	DT
cord-256444-grw5s2pf	579	7	membrane	membrane	NN
cord-256444-grw5s2pf	579	8	-	-	HYPH
cord-256444-grw5s2pf	579	9	bound	bind	VBN
cord-256444-grw5s2pf	579	10	metallopeptidase	metallopeptidase	NN
cord-256444-grw5s2pf	579	11	family	family	NN
cord-256444-grw5s2pf	579	12	and	and	CC
cord-256444-grw5s2pf	579	13	is	be	VBZ
cord-256444-grw5s2pf	579	14	widely	widely	RB
cord-256444-grw5s2pf	579	15	distributed	distribute	VBN
cord-256444-grw5s2pf	579	16	on	on	IN
cord-256444-grw5s2pf	579	17	diverse	diverse	JJ
cord-256444-grw5s2pf	579	18	cell	cell	NN
cord-256444-grw5s2pf	579	19	types	type	NNS
cord-256444-grw5s2pf	579	20	;	;	:
cord-256444-grw5s2pf	579	21	it	-PRON-	PRP
cord-256444-grw5s2pf	579	22	is	be	VBZ
cord-256444-grw5s2pf	579	23	highly	highly	RB
cord-256444-grw5s2pf	579	24	expressed	express	VBN
cord-256444-grw5s2pf	579	25	on	on	IN
cord-256444-grw5s2pf	579	26	the	the	DT
cord-256444-grw5s2pf	579	27	brush	brush	NN
cord-256444-grw5s2pf	579	28	border	border	NN
cord-256444-grw5s2pf	579	29	membrane	membrane	NN
cord-256444-grw5s2pf	579	30	of	of	IN
cord-256444-grw5s2pf	579	31	enterocytes	enterocyte	NNS
cord-256444-grw5s2pf	579	32	.	.	.
cord-256444-grw5s2pf	580	1	Some	some	DT
cord-256444-grw5s2pf	580	2	of	of	IN
cord-256444-grw5s2pf	580	3	the	the	DT
cord-256444-grw5s2pf	580	4	antibodies	antibody	NNS
cord-256444-grw5s2pf	580	5	against	against	IN
cord-256444-grw5s2pf	580	6	human	human	JJ
cord-256444-grw5s2pf	580	7	APN	APN	NNP
cord-256444-grw5s2pf	580	8	can	can	MD
cord-256444-grw5s2pf	580	9	block	block	VB
cord-256444-grw5s2pf	580	10	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	580	11	binding	bind	VBG
cord-256444-grw5s2pf	580	12	(	(	-LRB-
cord-256444-grw5s2pf	580	13	Yeager	Yeager	NNP
cord-256444-grw5s2pf	580	14	et	et	NNP
cord-256444-grw5s2pf	580	15	al	al	NNP
cord-256444-grw5s2pf	580	16	.	.	NNP
cord-256444-grw5s2pf	580	17	,	,	,
cord-256444-grw5s2pf	580	18	1992	1992	CD
cord-256444-grw5s2pf	580	19	)	)	-RRB-
cord-256444-grw5s2pf	580	20	;	;	:
cord-256444-grw5s2pf	580	21	however	however	RB
cord-256444-grw5s2pf	580	22	,	,	,
cord-256444-grw5s2pf	580	23	the	the	DT
cord-256444-grw5s2pf	580	24	catalytic	catalytic	JJ
cord-256444-grw5s2pf	580	25	site	site	NN
cord-256444-grw5s2pf	580	26	of	of	IN
cord-256444-grw5s2pf	580	27	the	the	DT
cord-256444-grw5s2pf	580	28	protease	protease	NN
cord-256444-grw5s2pf	580	29	activity	activity	NN
cord-256444-grw5s2pf	580	30	of	of	IN
cord-256444-grw5s2pf	580	31	APN	APN	NNP
cord-256444-grw5s2pf	580	32	is	be	VBZ
cord-256444-grw5s2pf	580	33	not	not	RB
cord-256444-grw5s2pf	580	34	required	require	VBN
cord-256444-grw5s2pf	580	35	for	for	IN
cord-256444-grw5s2pf	580	36	receptor	receptor	NN
cord-256444-grw5s2pf	580	37	function	function	NN
cord-256444-grw5s2pf	580	38	,	,	,
cord-256444-grw5s2pf	580	39	and	and	CC
cord-256444-grw5s2pf	580	40	the	the	DT
cord-256444-grw5s2pf	580	41	inhibitors	inhibitor	NNS
cord-256444-grw5s2pf	580	42	of	of	IN
cord-256444-grw5s2pf	580	43	APN	APN	NNP
cord-256444-grw5s2pf	580	44	do	do	VBP
cord-256444-grw5s2pf	580	45	not	not	RB
cord-256444-grw5s2pf	580	46	block	block	VB
cord-256444-grw5s2pf	580	47	viral	viral	JJ
cord-256444-grw5s2pf	580	48	infection	infection	NN
cord-256444-grw5s2pf	580	49	.	.	.
cord-256444-grw5s2pf	581	1	Similar	similar	JJ
cord-256444-grw5s2pf	581	2	to	to	IN
cord-256444-grw5s2pf	581	3	MHV	MHV	NNP
cord-256444-grw5s2pf	581	4	,	,	,
cord-256444-grw5s2pf	581	5	TGEV	TGEV	NNP
cord-256444-grw5s2pf	581	6	infects	infect	VBZ
cord-256444-grw5s2pf	581	7	polarized	polarized	JJ
cord-256444-grw5s2pf	581	8	cells	cell	NNS
cord-256444-grw5s2pf	581	9	through	through	IN
cord-256444-grw5s2pf	581	10	the	the	DT
cord-256444-grw5s2pf	581	11	apical	apical	JJ
cord-256444-grw5s2pf	581	12	,	,	,
cord-256444-grw5s2pf	581	13	but	but	CC
cord-256444-grw5s2pf	581	14	not	not	RB
cord-256444-grw5s2pf	581	15	the	the	DT
cord-256444-grw5s2pf	581	16	basolateral	basolateral	JJ
cord-256444-grw5s2pf	581	17	,	,	,
cord-256444-grw5s2pf	581	18	surface	surface	NN
cord-256444-grw5s2pf	581	19	(	(	-LRB-
cord-256444-grw5s2pf	581	20	Rossen	Rossen	NNP
cord-256444-grw5s2pf	581	21	et	et	NNP
cord-256444-grw5s2pf	581	22	al	al	NNP
cord-256444-grw5s2pf	581	23	.	.	NNP
cord-256444-grw5s2pf	581	24	,	,	,
cord-256444-grw5s2pf	581	25	1994	1994	CD
cord-256444-grw5s2pf	581	26	)	)	-RRB-
cord-256444-grw5s2pf	581	27	.	.	.
cord-256444-grw5s2pf	582	1	Again	again	RB
cord-256444-grw5s2pf	582	2	,	,	,
cord-256444-grw5s2pf	582	3	it	-PRON-	PRP
cord-256444-grw5s2pf	582	4	is	be	VBZ
cord-256444-grw5s2pf	582	5	not	not	RB
cord-256444-grw5s2pf	582	6	clear	clear	JJ
cord-256444-grw5s2pf	582	7	whether	whether	IN
cord-256444-grw5s2pf	582	8	this	this	DT
cord-256444-grw5s2pf	582	9	is	be	VBZ
cord-256444-grw5s2pf	582	10	restricted	restrict	VBN
cord-256444-grw5s2pf	582	11	by	by	IN
cord-256444-grw5s2pf	582	12	the	the	DT
cord-256444-grw5s2pf	582	13	differential	differential	JJ
cord-256444-grw5s2pf	582	14	expression	expression	NN
cord-256444-grw5s2pf	582	15	of	of	IN
cord-256444-grw5s2pf	582	16	APN	APN	NNP
cord-256444-grw5s2pf	582	17	on	on	IN
cord-256444-grw5s2pf	582	18	the	the	DT
cord-256444-grw5s2pf	582	19	different	different	JJ
cord-256444-grw5s2pf	582	20	sides	side	NNS
cord-256444-grw5s2pf	582	21	of	of	IN
cord-256444-grw5s2pf	582	22	the	the	DT
cord-256444-grw5s2pf	582	23	cells	cell	NNS
cord-256444-grw5s2pf	582	24	.	.	.
cord-256444-grw5s2pf	583	1	TGEV	TGEV	NNP
cord-256444-grw5s2pf	583	2	has	have	VBZ
cord-256444-grw5s2pf	583	3	also	also	RB
cord-256444-grw5s2pf	583	4	been	be	VBN
cord-256444-grw5s2pf	583	5	shown	show	VBN
cord-256444-grw5s2pf	583	6	to	to	TO
cord-256444-grw5s2pf	583	7	bind	bind	VB
cord-256444-grw5s2pf	583	8	to	to	IN
cord-256444-grw5s2pf	583	9	a	a	DT
cord-256444-grw5s2pf	583	10	200-kDa	200-kda	CD
cord-256444-grw5s2pf	583	11	protein	protein	NN
cord-256444-grw5s2pf	583	12	on	on	IN
cord-256444-grw5s2pf	583	13	the	the	DT
cord-256444-grw5s2pf	583	14	surface	surface	NN
cord-256444-grw5s2pf	583	15	of	of	IN
cord-256444-grw5s2pf	583	16	the	the	DT
cord-256444-grw5s2pf	583	17	enterocytes	enterocyte	NNS
cord-256444-grw5s2pf	583	18	on	on	IN
cord-256444-grw5s2pf	583	19	the	the	DT
cord-256444-grw5s2pf	583	20	villi	villi	NN
cord-256444-grw5s2pf	583	21	of	of	IN
cord-256444-grw5s2pf	583	22	the	the	DT
cord-256444-grw5s2pf	583	23	small	small	JJ
cord-256444-grw5s2pf	583	24	intestine	intestine	NN
cord-256444-grw5s2pf	583	25	(	(	-LRB-
cord-256444-grw5s2pf	583	26	Weingartl	Weingartl	NNP
cord-256444-grw5s2pf	583	27	and	and	CC
cord-256444-grw5s2pf	583	28	Derbyshire	Derbyshire	NNP
cord-256444-grw5s2pf	583	29	,	,	,
cord-256444-grw5s2pf	583	30	1994	1994	CD
cord-256444-grw5s2pf	583	31	)	)	-RRB-
cord-256444-grw5s2pf	583	32	.	.	.
cord-256444-grw5s2pf	584	1	PCRV	PCRV	NNP
cord-256444-grw5s2pf	584	2	does	do	VBZ
cord-256444-grw5s2pf	584	3	not	not	RB
cord-256444-grw5s2pf	584	4	bind	bind	VB
cord-256444-grw5s2pf	584	5	to	to	IN
cord-256444-grw5s2pf	584	6	this	this	DT
cord-256444-grw5s2pf	584	7	molecule	molecule	NN
cord-256444-grw5s2pf	584	8	.	.	.
cord-256444-grw5s2pf	585	1	Both	both	DT
cord-256444-grw5s2pf	585	2	the	the	DT
cord-256444-grw5s2pf	585	3	temporal	temporal	JJ
cord-256444-grw5s2pf	585	4	expression	expression	NN
cord-256444-grw5s2pf	585	5	(	(	-LRB-
cord-256444-grw5s2pf	585	6	mainly	mainly	RB
cord-256444-grw5s2pf	585	7	in	in	IN
cord-256444-grw5s2pf	585	8	the	the	DT
cord-256444-grw5s2pf	585	9	newborn	newborn	JJ
cord-256444-grw5s2pf	585	10	)	)	-RRB-
cord-256444-grw5s2pf	585	11	and	and	CC
cord-256444-grw5s2pf	585	12	spatial	spatial	JJ
cord-256444-grw5s2pf	585	13	distribution	distribution	NN
cord-256444-grw5s2pf	585	14	patterns	pattern	NNS
cord-256444-grw5s2pf	585	15	(	(	-LRB-
cord-256444-grw5s2pf	585	16	on	on	IN
cord-256444-grw5s2pf	585	17	the	the	DT
cord-256444-grw5s2pf	585	18	villi	villi	NN
cord-256444-grw5s2pf	585	19	of	of	IN
cord-256444-grw5s2pf	585	20	the	the	DT
cord-256444-grw5s2pf	585	21	gastrointestinal	gastrointestinal	JJ
cord-256444-grw5s2pf	585	22	tract	tract	NN
cord-256444-grw5s2pf	585	23	)	)	-RRB-
cord-256444-grw5s2pf	585	24	of	of	IN
cord-256444-grw5s2pf	585	25	the	the	DT
cord-256444-grw5s2pf	585	26	200-kDa	200-kda	CD
cord-256444-grw5s2pf	585	27	protein	protein	NN
cord-256444-grw5s2pf	585	28	correspond	correspond	VB
cord-256444-grw5s2pf	585	29	to	to	IN
cord-256444-grw5s2pf	585	30	the	the	DT
cord-256444-grw5s2pf	585	31	pattern	pattern	NN
cord-256444-grw5s2pf	585	32	of	of	IN
cord-256444-grw5s2pf	585	33	susceptibility	susceptibility	NN
cord-256444-grw5s2pf	585	34	of	of	IN
cord-256444-grw5s2pf	585	35	piglets	piglet	NNS
cord-256444-grw5s2pf	585	36	to	to	IN
cord-256444-grw5s2pf	585	37	TGEV	TGEV	NNP
cord-256444-grw5s2pf	585	38	infection	infection	NN
cord-256444-grw5s2pf	585	39	.	.	.
cord-256444-grw5s2pf	586	1	Thus	thus	RB
cord-256444-grw5s2pf	586	2	,	,	,
cord-256444-grw5s2pf	586	3	the	the	DT
cord-256444-grw5s2pf	586	4	expression	expression	NN
cord-256444-grw5s2pf	586	5	pattern	pattern	NN
cord-256444-grw5s2pf	586	6	of	of	IN
cord-256444-grw5s2pf	586	7	this	this	DT
cord-256444-grw5s2pf	586	8	molecule	molecule	NN
cord-256444-grw5s2pf	586	9	appears	appear	VBZ
cord-256444-grw5s2pf	586	10	to	to	TO
cord-256444-grw5s2pf	586	11	have	have	VB
cord-256444-grw5s2pf	586	12	a	a	DT
cord-256444-grw5s2pf	586	13	better	well	JJR
cord-256444-grw5s2pf	586	14	correlation	correlation	NN
cord-256444-grw5s2pf	586	15	than	than	IN
cord-256444-grw5s2pf	586	16	the	the	DT
cord-256444-grw5s2pf	586	17	porcine	porcine	JJ
cord-256444-grw5s2pf	586	18	A€	A€	NNP
cord-256444-grw5s2pf	586	19	"	"	''
cord-256444-grw5s2pf	586	20	with	with	IN
cord-256444-grw5s2pf	586	21	the	the	DT
cord-256444-grw5s2pf	586	22	tissue	tissue	NN
cord-256444-grw5s2pf	586	23	tropism	tropism	NN
cord-256444-grw5s2pf	586	24	of	of	IN
cord-256444-grw5s2pf	586	25	TGEV	TGEV	NNS
cord-256444-grw5s2pf	586	26	.	.	.
cord-256444-grw5s2pf	587	1	This	this	DT
cord-256444-grw5s2pf	587	2	200-kDa	200-kda	CD
cord-256444-grw5s2pf	587	3	molecule	molecule	NN
cord-256444-grw5s2pf	587	4	may	may	MD
cord-256444-grw5s2pf	587	5	be	be	VB
cord-256444-grw5s2pf	587	6	an	an	DT
cord-256444-grw5s2pf	587	7	alternative	alternative	JJ
cord-256444-grw5s2pf	587	8	receptor	receptor	NN
cord-256444-grw5s2pf	587	9	used	use	VBN
cord-256444-grw5s2pf	587	10	by	by	IN
cord-256444-grw5s2pf	587	11	TGEV	TGEV	NNP
cord-256444-grw5s2pf	587	12	.	.	.
cord-256444-grw5s2pf	588	1	The	the	DT
cord-256444-grw5s2pf	588	2	relative	relative	JJ
cord-256444-grw5s2pf	588	3	functional	functional	JJ
cord-256444-grw5s2pf	588	4	significance	significance	NN
cord-256444-grw5s2pf	588	5	of	of	IN
cord-256444-grw5s2pf	588	6	this	this	DT
cord-256444-grw5s2pf	588	7	molecule	molecule	NN
cord-256444-grw5s2pf	588	8	and	and	CC
cord-256444-grw5s2pf	588	9	A€	A€	NNP
cord-256444-grw5s2pf	588	10	"	"	''
cord-256444-grw5s2pf	588	11	as	as	IN
cord-256444-grw5s2pf	588	12	TGEV	TGEV	NNP
cord-256444-grw5s2pf	588	13	receptors	receptor	NNS
cord-256444-grw5s2pf	588	14	is	be	VBZ
cord-256444-grw5s2pf	588	15	not	not	RB
cord-256444-grw5s2pf	588	16	yet	yet	RB
cord-256444-grw5s2pf	588	17	clear	clear	JJ
cord-256444-grw5s2pf	588	18	.	.	.
cord-256444-grw5s2pf	589	1	The	the	DT
cord-256444-grw5s2pf	589	2	FIPV	FIPV	NNP
cord-256444-grw5s2pf	589	3	strains	strain	NNS
cord-256444-grw5s2pf	589	4	of	of	IN
cord-256444-grw5s2pf	589	5	FCV	FCV	NNP
cord-256444-grw5s2pf	589	6	and	and	CC
cord-256444-grw5s2pf	589	7	canine	canine	JJ
cord-256444-grw5s2pf	589	8	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	589	9	apparently	apparently	RB
cord-256444-grw5s2pf	589	10	utilize	utilize	VBP
cord-256444-grw5s2pf	589	11	the	the	DT
cord-256444-grw5s2pf	589	12	A€	A€	NNPS
cord-256444-grw5s2pf	589	13	"	"	''
cord-256444-grw5s2pf	589	14	of	of	IN
cord-256444-grw5s2pf	589	15	feline	feline	JJ
cord-256444-grw5s2pf	589	16	and	and	CC
cord-256444-grw5s2pf	589	17	canine	canine	JJ
cord-256444-grw5s2pf	589	18	species	specie	NNS
cord-256444-grw5s2pf	589	19	,	,	,
cord-256444-grw5s2pf	589	20	respectively	respectively	RB
cord-256444-grw5s2pf	589	21	,	,	,
cord-256444-grw5s2pf	589	22	as	as	IN
cord-256444-grw5s2pf	589	23	receptors	receptor	NNS
cord-256444-grw5s2pf	589	24	(	(	-LRB-
cord-256444-grw5s2pf	589	25	Benbacer	Benbacer	NNP
cord-256444-grw5s2pf	589	26	et	et	NNP
cord-256444-grw5s2pf	589	27	al	al	NNP
cord-256444-grw5s2pf	589	28	.	.	NNP
cord-256444-grw5s2pf	589	29	,	,	,
cord-256444-grw5s2pf	589	30	1997	1997	CD
cord-256444-grw5s2pf	589	31	)	)	-RRB-
cord-256444-grw5s2pf	589	32	.	.	.
cord-256444-grw5s2pf	590	1	Cross	cross	NN
cord-256444-grw5s2pf	590	2	-	-	JJ
cord-256444-grw5s2pf	590	3	species	species	JJ
cord-256444-grw5s2pf	590	4	utilization	utilization	NN
cord-256444-grw5s2pf	590	5	of	of	IN
cord-256444-grw5s2pf	590	6	feline	feline	JJ
cord-256444-grw5s2pf	590	7	A€	A€	NNS
cord-256444-grw5s2pf	590	8	"	"	''
cord-256444-grw5s2pf	590	9	by	by	IN
cord-256444-grw5s2pf	590	10	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	590	11	of	of	IN
cord-256444-grw5s2pf	590	12	different	different	JJ
cord-256444-grw5s2pf	590	13	species	specie	NNS
cord-256444-grw5s2pf	590	14	(	(	-LRB-
cord-256444-grw5s2pf	590	15	canine	canine	JJ
cord-256444-grw5s2pf	590	16	,	,	,
cord-256444-grw5s2pf	590	17	feline	feline	JJ
cord-256444-grw5s2pf	590	18	,	,	,
cord-256444-grw5s2pf	590	19	and	and	CC
cord-256444-grw5s2pf	590	20	human	human	NN
cord-256444-grw5s2pf	590	21	)	)	-RRB-
cord-256444-grw5s2pf	590	22	has	have	VBZ
cord-256444-grw5s2pf	590	23	also	also	RB
cord-256444-grw5s2pf	590	24	been	be	VBN
cord-256444-grw5s2pf	590	25	reported	report	VBN
cord-256444-grw5s2pf	591	1	(	(	-LRB-
cord-256444-grw5s2pf	591	2	Tresnan	Tresnan	NNP
cord-256444-grw5s2pf	591	3	et	et	FW
cord-256444-grw5s2pf	591	4	al	al	NNP
cord-256444-grw5s2pf	591	5	.	.	NNP
cord-256444-grw5s2pf	591	6	,	,	,
cord-256444-grw5s2pf	591	7	1996	1996	CD
cord-256444-grw5s2pf	591	8	)	)	-RRB-
cord-256444-grw5s2pf	591	9	.	.	.
cord-256444-grw5s2pf	592	1	FIPV	FIPV	NNS
cord-256444-grw5s2pf	592	2	,	,	,
cord-256444-grw5s2pf	592	3	however	however	RB
cord-256444-grw5s2pf	592	4	,	,	,
cord-256444-grw5s2pf	592	5	is	be	VBZ
cord-256444-grw5s2pf	592	6	unique	unique	JJ
cord-256444-grw5s2pf	592	7	among	among	IN
cord-256444-grw5s2pf	592	8	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	592	9	in	in	IN
cord-256444-grw5s2pf	592	10	that	that	IN
cord-256444-grw5s2pf	592	11	it	-PRON-	PRP
cord-256444-grw5s2pf	592	12	causes	cause	VBZ
cord-256444-grw5s2pf	592	13	an	an	DT
cord-256444-grw5s2pf	592	14	antibody	antibody	NN
cord-256444-grw5s2pf	592	15	-	-	HYPH
cord-256444-grw5s2pf	592	16	dependent	dependent	JJ
cord-256444-grw5s2pf	592	17	enhancement	enhancement	NN
cord-256444-grw5s2pf	592	18	(	(	-LRB-
cord-256444-grw5s2pf	592	19	ADE	ADE	NNP
cord-256444-grw5s2pf	592	20	)	)	-RRB-
cord-256444-grw5s2pf	592	21	phenomenon	phenomenon	NN
cord-256444-grw5s2pf	592	22	(	(	-LRB-
cord-256444-grw5s2pf	592	23	Weiss	Weiss	NNP
cord-256444-grw5s2pf	592	24	and	and	CC
cord-256444-grw5s2pf	592	25	Scott	Scott	NNP
cord-256444-grw5s2pf	592	26	,	,	,
cord-256444-grw5s2pf	592	27	19811	19811	CD
cord-256444-grw5s2pf	592	28	,	,	,
cord-256444-grw5s2pf	592	29	which	which	WDT
cord-256444-grw5s2pf	592	30	is	be	VBZ
cord-256444-grw5s2pf	592	31	the	the	DT
cord-256444-grw5s2pf	592	32	result	result	NN
cord-256444-grw5s2pf	592	33	of	of	IN
cord-256444-grw5s2pf	592	34	the	the	DT
cord-256444-grw5s2pf	592	35	binding	binding	NN
cord-256444-grw5s2pf	592	36	of	of	IN
cord-256444-grw5s2pf	592	37	the	the	DT
cord-256444-grw5s2pf	592	38	virus	virus	NN
cord-256444-grw5s2pf	592	39	-	-	HYPH
cord-256444-grw5s2pf	592	40	antibody	antibody	NN
cord-256444-grw5s2pf	592	41	complex	complex	NN
cord-256444-grw5s2pf	592	42	to	to	IN
cord-256444-grw5s2pf	592	43	Fc	Fc	NNP
cord-256444-grw5s2pf	592	44	receptors	receptor	NNS
cord-256444-grw5s2pf	592	45	on	on	IN
cord-256444-grw5s2pf	592	46	the	the	DT
cord-256444-grw5s2pf	592	47	surface	surface	NN
cord-256444-grw5s2pf	592	48	of	of	IN
cord-256444-grw5s2pf	592	49	macrophages	macrophage	NNS
cord-256444-grw5s2pf	592	50	,	,	,
cord-256444-grw5s2pf	592	51	leading	lead	VBG
cord-256444-grw5s2pf	592	52	to	to	IN
cord-256444-grw5s2pf	592	53	enhanced	enhanced	JJ
cord-256444-grw5s2pf	592	54	virus	virus	NN
cord-256444-grw5s2pf	592	55	uptake	uptake	NN
cord-256444-grw5s2pf	592	56	and	and	CC
cord-256444-grw5s2pf	592	57	spread	spread	NN
cord-256444-grw5s2pf	592	58	.	.	.
cord-256444-grw5s2pf	593	1	This	this	DT
cord-256444-grw5s2pf	593	2	ADE	ADE	NNP
cord-256444-grw5s2pf	593	3	phenomenon	phenomenon	NN
cord-256444-grw5s2pf	593	4	has	have	VBZ
cord-256444-grw5s2pf	593	5	been	be	VBN
cord-256444-grw5s2pf	593	6	attributed	attribute	VBN
cord-256444-grw5s2pf	593	7	to	to	IN
cord-256444-grw5s2pf	593	8	the	the	DT
cord-256444-grw5s2pf	593	9	S	S	NNP
cord-256444-grw5s2pf	593	10	protein	protein	NN
cord-256444-grw5s2pf	593	11	-	-	HYPH
cord-256444-grw5s2pf	593	12	antibody	antibody	NN
cord-256444-grw5s2pf	593	13	complex	complex	NN
cord-256444-grw5s2pf	593	14	(	(	-LRB-
cord-256444-grw5s2pf	593	15	Vennema	Vennema	NNP
cord-256444-grw5s2pf	593	16	et	et	FW
cord-256444-grw5s2pf	593	17	al	al	NNP
cord-256444-grw5s2pf	593	18	.	.	NNP
cord-256444-grw5s2pf	593	19	,	,	,
cord-256444-grw5s2pf	593	20	1990b	1990b	CD
cord-256444-grw5s2pf	593	21	;	;	:
cord-256444-grw5s2pf	593	22	Corapi	Corapi	NNP
cord-256444-grw5s2pf	593	23	et	et	NNP
cord-256444-grw5s2pf	593	24	al	al	NNP
cord-256444-grw5s2pf	593	25	.	.	NNP
cord-256444-grw5s2pf	593	26	,	,	,
cord-256444-grw5s2pf	593	27	1992	1992	CD
cord-256444-grw5s2pf	593	28	;	;	:
cord-256444-grw5s2pf	593	29	Olsen	Olsen	NNP
cord-256444-grw5s2pf	593	30	et	et	NNP
cord-256444-grw5s2pf	593	31	al	al	NNP
cord-256444-grw5s2pf	593	32	.	.	NNP
cord-256444-grw5s2pf	593	33	,	,	,
cord-256444-grw5s2pf	593	34	1992	1992	CD
cord-256444-grw5s2pf	593	35	)	)	-RRB-
cord-256444-grw5s2pf	593	36	.	.	.
cord-256444-grw5s2pf	594	1	The	the	DT
cord-256444-grw5s2pf	594	2	Fc	Fc	NNP
cord-256444-grw5s2pf	594	3	receptor	receptor	NN
cord-256444-grw5s2pf	594	4	may	may	MD
cord-256444-grw5s2pf	594	5	be	be	VB
cord-256444-grw5s2pf	594	6	a	a	DT
cord-256444-grw5s2pf	594	7	co	co	NN
cord-256444-grw5s2pf	594	8	-	-	NN
cord-256444-grw5s2pf	594	9	factor	factor	NN
cord-256444-grw5s2pf	594	10	or	or	CC
cord-256444-grw5s2pf	594	11	an	an	DT
cord-256444-grw5s2pf	594	12	alternative	alternative	JJ
cord-256444-grw5s2pf	594	13	receptor	receptor	NN
cord-256444-grw5s2pf	594	14	for	for	IN
cord-256444-grw5s2pf	594	15	FIPV	FIPV	NNS
cord-256444-grw5s2pf	594	16	entry	entry	NN
cord-256444-grw5s2pf	594	17	into	into	IN
cord-256444-grw5s2pf	594	18	macrophages	macrophage	NNS
cord-256444-grw5s2pf	594	19	.	.	.
cord-256444-grw5s2pf	595	1	In	in	IN
cord-256444-grw5s2pf	595	2	this	this	DT
cord-256444-grw5s2pf	595	3	regard	regard	NN
cord-256444-grw5s2pf	595	4	,	,	,
cord-256444-grw5s2pf	595	5	the	the	DT
cord-256444-grw5s2pf	595	6	S	S	NNP
cord-256444-grw5s2pf	595	7	protein	protein	NN
cord-256444-grw5s2pf	595	8	of	of	IN
cord-256444-grw5s2pf	595	9	MHV	MHV	NNP
cord-256444-grw5s2pf	595	10	has	have	VBZ
cord-256444-grw5s2pf	595	11	been	be	VBN
cord-256444-grw5s2pf	595	12	shown	show	VBN
cord-256444-grw5s2pf	595	13	to	to	TO
cord-256444-grw5s2pf	595	14	have	have	VB
cord-256444-grw5s2pf	595	15	limited	limit	VBN
cord-256444-grw5s2pf	595	16	sequence	sequence	NN
cord-256444-grw5s2pf	595	17	homology	homology	NN
cord-256444-grw5s2pf	595	18	with	with	IN
cord-256444-grw5s2pf	595	19	the	the	DT
cord-256444-grw5s2pf	595	20	murine	murine	JJ
cord-256444-grw5s2pf	595	21	Fc	Fc	NNP
cord-256444-grw5s2pf	595	22	receptor	receptor	NN
cord-256444-grw5s2pf	595	23	and	and	CC
cord-256444-grw5s2pf	595	24	to	to	TO
cord-256444-grw5s2pf	595	25	have	have	VB
cord-256444-grw5s2pf	595	26	the	the	DT
cord-256444-grw5s2pf	595	27	ability	ability	NN
cord-256444-grw5s2pf	595	28	to	to	TO
cord-256444-grw5s2pf	595	29	bind	bind	VB
cord-256444-grw5s2pf	595	30	to	to	IN
cord-256444-grw5s2pf	595	31	the	the	DT
cord-256444-grw5s2pf	595	32	Fc	Fc	NNP
cord-256444-grw5s2pf	595	33	fragment	fragment	NN
cord-256444-grw5s2pf	595	34	of	of	IN
cord-256444-grw5s2pf	595	35	immunoglobulin	immunoglobulin	NN
cord-256444-grw5s2pf	595	36	Oleszak	Oleszak	NNP
cord-256444-grw5s2pf	595	37	et	et	NNP
cord-256444-grw5s2pf	595	38	al	al	NNP
cord-256444-grw5s2pf	595	39	.	.	NNP
cord-256444-grw5s2pf	595	40	,	,	,
cord-256444-grw5s2pf	595	41	1992	1992	CD
cord-256444-grw5s2pf	595	42	)	)	-RRB-
cord-256444-grw5s2pf	595	43	.	.	.
cord-256444-grw5s2pf	596	1	Whether	whether	IN
cord-256444-grw5s2pf	596	2	the	the	DT
cord-256444-grw5s2pf	596	3	Fc	Fc	NNP
cord-256444-grw5s2pf	596	4	receptor	receptor	NN
cord-256444-grw5s2pf	596	5	plays	play	VBZ
cord-256444-grw5s2pf	596	6	a	a	DT
cord-256444-grw5s2pf	596	7	role	role	NN
cord-256444-grw5s2pf	596	8	in	in	IN
cord-256444-grw5s2pf	596	9	MHV	MHV	NNP
cord-256444-grw5s2pf	596	10	infection	infection	NN
cord-256444-grw5s2pf	596	11	is	be	VBZ
cord-256444-grw5s2pf	596	12	not	not	RB
cord-256444-grw5s2pf	596	13	clear	clear	JJ
cord-256444-grw5s2pf	596	14	.	.	.
cord-256444-grw5s2pf	597	1	However	however	RB
cord-256444-grw5s2pf	597	2	,	,	,
cord-256444-grw5s2pf	597	3	MHV	MHV	NNP
cord-256444-grw5s2pf	597	4	does	do	VBZ
cord-256444-grw5s2pf	597	5	not	not	RB
cord-256444-grw5s2pf	597	6	exhibit	exhibit	VB
cord-256444-grw5s2pf	597	7	ADE	ADE	NNP
cord-256444-grw5s2pf	597	8	.	.	.
cord-256444-grw5s2pf	598	1	c.	c.	NNP
cord-256444-grw5s2pf	598	2	Receptors	Receptors	NNP
cord-256444-grw5s2pf	598	3	for	for	IN
cord-256444-grw5s2pf	598	4	Other	Other	NNP
cord-256444-grw5s2pf	598	5	Coronaviruses	Coronaviruses	NNPS
cord-256444-grw5s2pf	598	6	.	.	.
cord-256444-grw5s2pf	599	1	Sialic	sialic	NN
cord-256444-grw5s2pf	599	2	acid	acid	NN
cord-256444-grw5s2pf	599	3	(	(	-LRB-
cord-256444-grw5s2pf	599	4	N	n	CD
cord-256444-grw5s2pf	599	5	-	-	HYPH
cord-256444-grw5s2pf	599	6	acetyl-9	acetyl-9	NNP
cord-256444-grw5s2pf	599	7	-	-	HYPH
cord-256444-grw5s2pf	599	8	0acetylneuraminic	0acetylneuraminic	CD
cord-256444-grw5s2pf	599	9	acid)-containing	acid)-containe	VBG
cord-256444-grw5s2pf	599	10	glycoproteins	glycoprotein	NNS
cord-256444-grw5s2pf	599	11	are	be	VBP
cord-256444-grw5s2pf	599	12	probably	probably	RB
cord-256444-grw5s2pf	599	13	a	a	DT
cord-256444-grw5s2pf	599	14	component	component	NN
cord-256444-grw5s2pf	599	15	of	of	IN
cord-256444-grw5s2pf	599	16	the	the	DT
cord-256444-grw5s2pf	599	17	cell	cell	NN
cord-256444-grw5s2pf	599	18	surface	surface	NN
cord-256444-grw5s2pf	599	19	molecules	molecule	NNS
cord-256444-grw5s2pf	599	20	required	require	VBN
cord-256444-grw5s2pf	599	21	for	for	IN
cord-256444-grw5s2pf	599	22	BCV	BCV	NNP
cord-256444-grw5s2pf	599	23	and	and	CC
cord-256444-grw5s2pf	599	24	HCV	HCV	NNP
cord-256444-grw5s2pf	599	25	-	-	HYPH
cord-256444-grw5s2pf	599	26	OC43	OC43	NNP
cord-256444-grw5s2pf	599	27	infection	infection	NN
cord-256444-grw5s2pf	599	28	because	because	IN
cord-256444-grw5s2pf	599	29	the	the	DT
cord-256444-grw5s2pf	599	30	removal	removal	NN
cord-256444-grw5s2pf	599	31	of	of	IN
cord-256444-grw5s2pf	599	32	sialic	sialic	JJ
cord-256444-grw5s2pf	599	33	acids	acid	NNS
cord-256444-grw5s2pf	599	34	inhibits	inhibit	VBZ
cord-256444-grw5s2pf	599	35	BCV	BCV	NNP
cord-256444-grw5s2pf	599	36	infection	infection	NN
cord-256444-grw5s2pf	599	37	and	and	CC
cord-256444-grw5s2pf	599	38	resialylation	resialylation	NN
cord-256444-grw5s2pf	599	39	restores	restore	VBZ
cord-256444-grw5s2pf	599	40	virus	virus	NN
cord-256444-grw5s2pf	599	41	infectivity	infectivity	NN
cord-256444-grw5s2pf	599	42	;	;	:
cord-256444-grw5s2pf	599	43	however	however	RB
cord-256444-grw5s2pf	599	44	,	,	,
cord-256444-grw5s2pf	599	45	it	-PRON-	PRP
cord-256444-grw5s2pf	599	46	is	be	VBZ
cord-256444-grw5s2pf	599	47	unlikely	unlikely	JJ
cord-256444-grw5s2pf	599	48	that	that	IN
cord-256444-grw5s2pf	599	49	it	-PRON-	PRP
cord-256444-grw5s2pf	599	50	is	be	VBZ
cord-256444-grw5s2pf	599	51	the	the	DT
cord-256444-grw5s2pf	599	52	primary	primary	JJ
cord-256444-grw5s2pf	599	53	receptor	receptor	NN
cord-256444-grw5s2pf	599	54	molecule	molecule	NN
cord-256444-grw5s2pf	599	55	used	use	VBN
cord-256444-grw5s2pf	599	56	by	by	IN
cord-256444-grw5s2pf	599	57	these	these	DT
cord-256444-grw5s2pf	599	58	viruses	virus	NNS
cord-256444-grw5s2pf	599	59	since	since	IN
cord-256444-grw5s2pf	599	60	the	the	DT
cord-256444-grw5s2pf	599	61	distribution	distribution	NN
cord-256444-grw5s2pf	599	62	of	of	IN
cord-256444-grw5s2pf	599	63	these	these	DT
cord-256444-grw5s2pf	599	64	molecules	molecule	NNS
cord-256444-grw5s2pf	599	65	is	be	VBZ
cord-256444-grw5s2pf	599	66	more	more	RBR
cord-256444-grw5s2pf	599	67	widespread	widespread	JJ
cord-256444-grw5s2pf	599	68	than	than	IN
cord-256444-grw5s2pf	599	69	the	the	DT
cord-256444-grw5s2pf	599	70	susceptible	susceptible	JJ
cord-256444-grw5s2pf	599	71	target	target	NN
cord-256444-grw5s2pf	599	72	cells	cell	NNS
cord-256444-grw5s2pf	599	73	.	.	.
cord-256444-grw5s2pf	600	1	The	the	DT
cord-256444-grw5s2pf	600	2	identity	identity	NN
cord-256444-grw5s2pf	600	3	of	of	IN
cord-256444-grw5s2pf	600	4	the	the	DT
cord-256444-grw5s2pf	600	5	specific	specific	JJ
cord-256444-grw5s2pf	600	6	receptor	receptor	NN
cord-256444-grw5s2pf	600	7	for	for	IN
cord-256444-grw5s2pf	600	8	these	these	DT
cord-256444-grw5s2pf	600	9	viruses	virus	NNS
cord-256444-grw5s2pf	600	10	has	have	VBZ
cord-256444-grw5s2pf	600	11	not	not	RB
cord-256444-grw5s2pf	600	12	been	be	VBN
cord-256444-grw5s2pf	600	13	determined	determine	VBN
cord-256444-grw5s2pf	600	14	.	.	.
cord-256444-grw5s2pf	601	1	For	for	IN
cord-256444-grw5s2pf	601	2	HCV	HCV	NNP
cord-256444-grw5s2pf	601	3	-	-	HYPH
cord-256444-grw5s2pf	601	4	OC43	OC43	NNP
cord-256444-grw5s2pf	601	5	,	,	,
cord-256444-grw5s2pf	601	6	it	-PRON-	PRP
cord-256444-grw5s2pf	601	7	has	have	VBZ
cord-256444-grw5s2pf	601	8	been	be	VBN
cord-256444-grw5s2pf	601	9	shown	show	VBN
cord-256444-grw5s2pf	601	10	that	that	IN
cord-256444-grw5s2pf	601	11	the	the	DT
cord-256444-grw5s2pf	601	12	virus	virus	NN
cord-256444-grw5s2pf	601	13	binds	bind	VBZ
cord-256444-grw5s2pf	601	14	to	to	IN
cord-256444-grw5s2pf	601	15	a	a	DT
cord-256444-grw5s2pf	601	16	major	major	JJ
cord-256444-grw5s2pf	601	17	histocompatibility	histocompatibility	NN
cord-256444-grw5s2pf	601	18	complex	complex	JJ
cord-256444-grw5s2pf	601	19	class	class	NN
cord-256444-grw5s2pf	601	20	I	-PRON-	PRP
cord-256444-grw5s2pf	601	21	molecule	molecule	VBP
cord-256444-grw5s2pf	601	22	(	(	-LRB-
cord-256444-grw5s2pf	601	23	Collins	Collins	NNP
cord-256444-grw5s2pf	601	24	,	,	,
cord-256444-grw5s2pf	601	25	1994	1994	CD
cord-256444-grw5s2pf	601	26	)	)	-RRB-
cord-256444-grw5s2pf	601	27	.	.	.
cord-256444-grw5s2pf	602	1	However	however	RB
cord-256444-grw5s2pf	602	2	,	,	,
cord-256444-grw5s2pf	602	3	the	the	DT
cord-256444-grw5s2pf	602	4	receptor	receptor	NN
cord-256444-grw5s2pf	602	5	function	function	NN
cord-256444-grw5s2pf	602	6	of	of	IN
cord-256444-grw5s2pf	602	7	this	this	DT
cord-256444-grw5s2pf	602	8	molecule	molecule	NN
cord-256444-grw5s2pf	602	9	has	have	VBZ
cord-256444-grw5s2pf	602	10	not	not	RB
cord-256444-grw5s2pf	602	11	been	be	VBN
cord-256444-grw5s2pf	602	12	established	establish	VBN
cord-256444-grw5s2pf	602	13	.	.	.
cord-256444-grw5s2pf	603	1	The	the	DT
cord-256444-grw5s2pf	603	2	mechanism	mechanism	NN
cord-256444-grw5s2pf	603	3	of	of	IN
cord-256444-grw5s2pf	603	4	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	603	5	entry	entry	NN
cord-256444-grw5s2pf	603	6	into	into	IN
cord-256444-grw5s2pf	603	7	target	target	NN
cord-256444-grw5s2pf	603	8	cells	cell	NNS
cord-256444-grw5s2pf	603	9	has	have	VBZ
cord-256444-grw5s2pf	603	10	been	be	VBN
cord-256444-grw5s2pf	603	11	controversial	controversial	JJ
cord-256444-grw5s2pf	603	12	.	.	.
cord-256444-grw5s2pf	604	1	Early	early	RB
cord-256444-grw5s2pf	604	2	electron	electron	NN
cord-256444-grw5s2pf	604	3	microscopic	microscopic	JJ
cord-256444-grw5s2pf	604	4	studies	study	NNS
cord-256444-grw5s2pf	604	5	visualized	visualize	VBD
cord-256444-grw5s2pf	604	6	virus	virus	NN
cord-256444-grw5s2pf	604	7	(	(	-LRB-
cord-256444-grw5s2pf	604	8	MHV	MHV	NNP
cord-256444-grw5s2pf	604	9	and	and	CC
cord-256444-grw5s2pf	604	10	IBV	IBV	NNP
cord-256444-grw5s2pf	604	11	)	)	-RRB-
cord-256444-grw5s2pf	604	12	particles	particle	NNS
cord-256444-grw5s2pf	604	13	inside	inside	IN
cord-256444-grw5s2pf	604	14	lysosome	lysosome	NN
cord-256444-grw5s2pf	604	15	-	-	HYPH
cord-256444-grw5s2pf	604	16	like	like	JJ
cord-256444-grw5s2pf	604	17	vesicles	vesicle	NNS
cord-256444-grw5s2pf	604	18	near	near	IN
cord-256444-grw5s2pf	604	19	plasma	plasma	NN
cord-256444-grw5s2pf	604	20	membranes	membrane	NNS
cord-256444-grw5s2pf	604	21	,	,	,
cord-256444-grw5s2pf	604	22	suggesting	suggest	VBG
cord-256444-grw5s2pf	604	23	that	that	IN
cord-256444-grw5s2pf	604	24	virus	virus	NN
cord-256444-grw5s2pf	604	25	enters	enter	VBZ
cord-256444-grw5s2pf	604	26	cells	cell	NNS
cord-256444-grw5s2pf	604	27	by	by	IN
cord-256444-grw5s2pf	604	28	endocytosis	endocytosis	NN
cord-256444-grw5s2pf	604	29	(	(	-LRB-
cord-256444-grw5s2pf	604	30	"	"	``
cord-256444-grw5s2pf	604	31	viropexis	viropexis	NNP
cord-256444-grw5s2pf	604	32	"	"	''
cord-256444-grw5s2pf	604	33	)	)	-RRB-
cord-256444-grw5s2pf	605	1	(	(	-LRB-
cord-256444-grw5s2pf	605	2	David	David	NNP
cord-256444-grw5s2pf	605	3	-	-	HYPH
cord-256444-grw5s2pf	605	4	Ferreira	Ferreira	NNP
cord-256444-grw5s2pf	605	5	and	and	CC
cord-256444-grw5s2pf	605	6	Manaker	Manaker	NNP
cord-256444-grw5s2pf	605	7	,	,	,
cord-256444-grw5s2pf	605	8	1965	1965	CD
cord-256444-grw5s2pf	605	9	)	)	-RRB-
cord-256444-grw5s2pf	605	10	;	;	:
cord-256444-grw5s2pf	605	11	however	however	RB
cord-256444-grw5s2pf	605	12	,	,	,
cord-256444-grw5s2pf	605	13	other	other	JJ
cord-256444-grw5s2pf	605	14	studies	study	NNS
cord-256444-grw5s2pf	605	15	suggested	suggest	VBD
cord-256444-grw5s2pf	605	16	that	that	IN
cord-256444-grw5s2pf	605	17	virus	virus	NN
cord-256444-grw5s2pf	605	18	enters	enter	VBZ
cord-256444-grw5s2pf	605	19	cells	cell	NNS
cord-256444-grw5s2pf	605	20	by	by	IN
cord-256444-grw5s2pf	605	21	direct	direct	JJ
cord-256444-grw5s2pf	605	22	fusion	fusion	NN
cord-256444-grw5s2pf	605	23	between	between	IN
cord-256444-grw5s2pf	605	24	virions	virion	NNS
cord-256444-grw5s2pf	605	25	and	and	CC
cord-256444-grw5s2pf	605	26	the	the	DT
cord-256444-grw5s2pf	605	27	plasma	plasma	NN
cord-256444-grw5s2pf	605	28	membrane	membrane	NN
cord-256444-grw5s2pf	605	29	(	(	-LRB-
cord-256444-grw5s2pf	605	30	Doughri	Doughri	NNP
cord-256444-grw5s2pf	605	31	et	et	FW
cord-256444-grw5s2pf	605	32	al	al	NNP
cord-256444-grw5s2pf	605	33	.	.	NNP
cord-256444-grw5s2pf	605	34	,	,	,
cord-256444-grw5s2pf	605	35	1976	1976	CD
cord-256444-grw5s2pf	605	36	)	)	-RRB-
cord-256444-grw5s2pf	605	37	.	.	.
cord-256444-grw5s2pf	606	1	Lysosomotropic	lysosomotropic	JJ
cord-256444-grw5s2pf	606	2	drugs	drug	NNS
cord-256444-grw5s2pf	606	3	,	,	,
cord-256444-grw5s2pf	606	4	such	such	JJ
cord-256444-grw5s2pf	606	5	as	as	IN
cord-256444-grw5s2pf	606	6	ammonium	ammonium	NN
cord-256444-grw5s2pf	606	7	chloride	chloride	NN
cord-256444-grw5s2pf	606	8	and	and	CC
cord-256444-grw5s2pf	606	9	chloroquine	chloroquine	NN
cord-256444-grw5s2pf	606	10	,	,	,
cord-256444-grw5s2pf	606	11	inhibited	inhibited	JJ
cord-256444-grw5s2pf	606	12	MHV-3	MHV-3	NNP
cord-256444-grw5s2pf	606	13	virus	virus	NN
cord-256444-grw5s2pf	606	14	entry	entry	NN
cord-256444-grw5s2pf	606	15	(	(	-LRB-
cord-256444-grw5s2pf	606	16	Krzystyniak	Krzystyniak	NNP
cord-256444-grw5s2pf	606	17	and	and	CC
cord-256444-grw5s2pf	606	18	Dupuy	Dupuy	NNP
cord-256444-grw5s2pf	606	19	,	,	,
cord-256444-grw5s2pf	606	20	1984	1984	CD
cord-256444-grw5s2pf	606	21	)	)	-RRB-
cord-256444-grw5s2pf	606	22	.	.	.
cord-256444-grw5s2pf	607	1	Also	also	RB
cord-256444-grw5s2pf	607	2	,	,	,
cord-256444-grw5s2pf	607	3	MHV	mhv	NN
cord-256444-grw5s2pf	607	4	-	-	HYPH
cord-256444-grw5s2pf	607	5	specific	specific	JJ
cord-256444-grw5s2pf	607	6	antibodies	antibody	NNS
cord-256444-grw5s2pf	607	7	did	do	VBD
cord-256444-grw5s2pf	607	8	not	not	RB
cord-256444-grw5s2pf	607	9	lyse	lyse	VB
cord-256444-grw5s2pf	607	10	virusinfected	virusinfected	JJ
cord-256444-grw5s2pf	607	11	cells	cell	NNS
cord-256444-grw5s2pf	607	12	during	during	IN
cord-256444-grw5s2pf	607	13	the	the	DT
cord-256444-grw5s2pf	607	14	virus	virus	NN
cord-256444-grw5s2pf	607	15	-	-	HYPH
cord-256444-grw5s2pf	607	16	entry	entry	NN
cord-256444-grw5s2pf	607	17	process	process	NN
cord-256444-grw5s2pf	607	18	,	,	,
cord-256444-grw5s2pf	607	19	as	as	IN
cord-256444-grw5s2pf	607	20	would	would	MD
cord-256444-grw5s2pf	607	21	be	be	VB
cord-256444-grw5s2pf	607	22	the	the	DT
cord-256444-grw5s2pf	607	23	case	case	NN
cord-256444-grw5s2pf	607	24	if	if	IN
cord-256444-grw5s2pf	607	25	the	the	DT
cord-256444-grw5s2pf	607	26	virus	virus	NN
cord-256444-grw5s2pf	607	27	fused	fuse	VBN
cord-256444-grw5s2pf	607	28	with	with	IN
cord-256444-grw5s2pf	607	29	the	the	DT
cord-256444-grw5s2pf	607	30	cell	cell	NN
cord-256444-grw5s2pf	607	31	membrane	membrane	NN
cord-256444-grw5s2pf	607	32	(	(	-LRB-
cord-256444-grw5s2pf	607	33	Krzystyniak	Krzystyniak	NNP
cord-256444-grw5s2pf	607	34	and	and	CC
cord-256444-grw5s2pf	607	35	Dupuy	Dupuy	NNP
cord-256444-grw5s2pf	607	36	,	,	,
cord-256444-grw5s2pf	607	37	1984	1984	CD
cord-256444-grw5s2pf	607	38	)	)	-RRB-
cord-256444-grw5s2pf	607	39	.	.	.
cord-256444-grw5s2pf	608	1	These	these	DT
cord-256444-grw5s2pf	608	2	results	result	NNS
cord-256444-grw5s2pf	608	3	suggested	suggest	VBD
cord-256444-grw5s2pf	608	4	that	that	IN
cord-256444-grw5s2pf	608	5	MHV-3	MHV-3	NNP
cord-256444-grw5s2pf	608	6	enters	enter	VBZ
cord-256444-grw5s2pf	608	7	cells	cell	NNS
cord-256444-grw5s2pf	608	8	by	by	IN
cord-256444-grw5s2pf	608	9	an	an	DT
cord-256444-grw5s2pf	608	10	endocytotic	endocytotic	JJ
cord-256444-grw5s2pf	608	11	pathway	pathway	NN
cord-256444-grw5s2pf	608	12	.	.	.
cord-256444-grw5s2pf	609	1	Similar	similar	JJ
cord-256444-grw5s2pf	609	2	studies	study	NNS
cord-256444-grw5s2pf	609	3	using	use	VBG
cord-256444-grw5s2pf	609	4	the	the	DT
cord-256444-grw5s2pf	609	5	A59	A59	NNP
cord-256444-grw5s2pf	609	6	strain	strain	NN
cord-256444-grw5s2pf	609	7	of	of	IN
cord-256444-grw5s2pf	609	8	MHV	MHV	NNP
cord-256444-grw5s2pf	609	9	,	,	,
cord-256444-grw5s2pf	609	10	however	however	RB
cord-256444-grw5s2pf	609	11	,	,	,
cord-256444-grw5s2pf	609	12	showed	show	VBD
cord-256444-grw5s2pf	609	13	that	that	IN
cord-256444-grw5s2pf	609	14	ammonium	ammonium	NN
cord-256444-grw5s2pf	609	15	chloride	chloride	NN
cord-256444-grw5s2pf	609	16	delayed	delay	VBN
cord-256444-grw5s2pf	609	17	,	,	,
cord-256444-grw5s2pf	609	18	but	but	CC
cord-256444-grw5s2pf	609	19	did	do	VBD
cord-256444-grw5s2pf	609	20	not	not	RB
cord-256444-grw5s2pf	609	21	inhibit	inhibit	VB
cord-256444-grw5s2pf	609	22	,	,	,
cord-256444-grw5s2pf	609	23	the	the	DT
cord-256444-grw5s2pf	609	24	viral	viral	JJ
cord-256444-grw5s2pf	609	25	infection	infection	NN
cord-256444-grw5s2pf	609	26	of	of	IN
cord-256444-grw5s2pf	609	27	L-2	L-2	NNP
cord-256444-grw5s2pf	609	28	cells	cell	NNS
cord-256444-grw5s2pf	609	29	(	(	-LRB-
cord-256444-grw5s2pf	609	30	Mizzen	Mizzen	NNP
cord-256444-grw5s2pf	609	31	et	et	NNP
cord-256444-grw5s2pf	609	32	al	al	NNP
cord-256444-grw5s2pf	609	33	.	.	NNP
cord-256444-grw5s2pf	609	34	,	,	,
cord-256444-grw5s2pf	609	35	1985	1985	CD
cord-256444-grw5s2pf	609	36	)	)	-RRB-
cord-256444-grw5s2pf	609	37	.	.	.
cord-256444-grw5s2pf	610	1	The	the	DT
cord-256444-grw5s2pf	610	2	effects	effect	NNS
cord-256444-grw5s2pf	610	3	of	of	IN
cord-256444-grw5s2pf	610	4	ammonium	ammonium	NN
cord-256444-grw5s2pf	610	5	chloride	chloride	NN
cord-256444-grw5s2pf	610	6	were	be	VBD
cord-256444-grw5s2pf	610	7	interpreted	interpret	VBN
cord-256444-grw5s2pf	610	8	to	to	TO
cord-256444-grw5s2pf	610	9	be	be	VB
cord-256444-grw5s2pf	610	10	inhibiting	inhibit	VBG
cord-256444-grw5s2pf	610	11	virus	virus	NN
cord-256444-grw5s2pf	610	12	uncoating	uncoate	VBG
cord-256444-grw5s2pf	610	13	in	in	IN
cord-256444-grw5s2pf	610	14	this	this	DT
cord-256444-grw5s2pf	610	15	case	case	NN
cord-256444-grw5s2pf	610	16	.	.	.
cord-256444-grw5s2pf	611	1	Recent	recent	JJ
cord-256444-grw5s2pf	611	2	studies	study	NNS
cord-256444-grw5s2pf	611	3	by	by	IN
cord-256444-grw5s2pf	611	4	the	the	DT
cord-256444-grw5s2pf	611	5	same	same	JJ
cord-256444-grw5s2pf	611	6	group	group	NN
cord-256444-grw5s2pf	611	7	have	have	VBP
cord-256444-grw5s2pf	611	8	further	further	RB
cord-256444-grw5s2pf	611	9	shown	show	VBN
cord-256444-grw5s2pf	611	10	that	that	IN
cord-256444-grw5s2pf	611	11	only	only	RB
cord-256444-grw5s2pf	611	12	a	a	DT
cord-256444-grw5s2pf	611	13	small	small	JJ
cord-256444-grw5s2pf	611	14	proportion	proportion	NN
cord-256444-grw5s2pf	611	15	of	of	IN
cord-256444-grw5s2pf	611	16	adsorbed	adsorb	VBN
cord-256444-grw5s2pf	611	17	virus	virus	NN
cord-256444-grw5s2pf	611	18	enters	enter	VBZ
cord-256444-grw5s2pf	611	19	cells	cell	NNS
cord-256444-grw5s2pf	611	20	by	by	IN
cord-256444-grw5s2pf	611	21	the	the	DT
cord-256444-grw5s2pf	611	22	endocytotic	endocytotic	JJ
cord-256444-grw5s2pf	611	23	pathway	pathway	NN
cord-256444-grw5s2pf	611	24	since	since	IN
cord-256444-grw5s2pf	611	25	ammonium	ammonium	NN
cord-256444-grw5s2pf	611	26	chloride	chloride	NN
cord-256444-grw5s2pf	611	27	,	,	,
cord-256444-grw5s2pf	611	28	chloroquine	chloroquine	NN
cord-256444-grw5s2pf	611	29	,	,	,
cord-256444-grw5s2pf	611	30	and	and	CC
cord-256444-grw5s2pf	611	31	dansylcadaverine	dansylcadaverine	NN
cord-256444-grw5s2pf	611	32	,	,	,
cord-256444-grw5s2pf	611	33	all	all	DT
cord-256444-grw5s2pf	611	34	of	of	IN
cord-256444-grw5s2pf	611	35	which	which	WDT
cord-256444-grw5s2pf	611	36	inhibit	inhibit	VBP
cord-256444-grw5s2pf	611	37	receptor	receptor	NN
cord-256444-grw5s2pf	611	38	-	-	HYPH
cord-256444-grw5s2pf	611	39	mediated	mediate	VBN
cord-256444-grw5s2pf	611	40	endocytosis	endocytosis	NN
cord-256444-grw5s2pf	611	41	,	,	,
cord-256444-grw5s2pf	611	42	did	do	VBD
cord-256444-grw5s2pf	611	43	not	not	RB
cord-256444-grw5s2pf	611	44	have	have	VB
cord-256444-grw5s2pf	611	45	significant	significant	JJ
cord-256444-grw5s2pf	611	46	effects	effect	NNS
cord-256444-grw5s2pf	611	47	on	on	IN
cord-256444-grw5s2pf	611	48	MHV	MHV	NNP
cord-256444-grw5s2pf	611	49	entry	entry	NN
cord-256444-grw5s2pf	612	1	(	(	-LRB-
cord-256444-grw5s2pf	612	2	Kooi	Kooi	NNP
cord-256444-grw5s2pf	612	3	et	et	NNP
cord-256444-grw5s2pf	612	4	al	al	NNP
cord-256444-grw5s2pf	612	5	.	.	NNP
cord-256444-grw5s2pf	612	6	,	,	,
cord-256444-grw5s2pf	612	7	1991	1991	CD
cord-256444-grw5s2pf	612	8	)	)	-RRB-
cord-256444-grw5s2pf	612	9	.	.	.
cord-256444-grw5s2pf	613	1	The	the	DT
cord-256444-grw5s2pf	613	2	majority	majority	NN
cord-256444-grw5s2pf	613	3	of	of	IN
cord-256444-grw5s2pf	613	4	MHV	MHV	NNP
cord-256444-grw5s2pf	613	5	particles	particle	NNS
cord-256444-grw5s2pf	613	6	enter	enter	VBP
cord-256444-grw5s2pf	613	7	cells	cell	NNS
cord-256444-grw5s2pf	613	8	by	by	IN
cord-256444-grw5s2pf	613	9	virus	virus	NN
cord-256444-grw5s2pf	613	10	-	-	HYPH
cord-256444-grw5s2pf	613	11	cell	cell	NN
cord-256444-grw5s2pf	613	12	fusion	fusion	NN
cord-256444-grw5s2pf	613	13	at	at	IN
cord-256444-grw5s2pf	613	14	the	the	DT
cord-256444-grw5s2pf	613	15	plasma	plasma	NN
cord-256444-grw5s2pf	613	16	membrane	membrane	NN
cord-256444-grw5s2pf	613	17	.	.	.
cord-256444-grw5s2pf	614	1	This	this	DT
cord-256444-grw5s2pf	614	2	interpretation	interpretation	NN
cord-256444-grw5s2pf	614	3	is	be	VBZ
cord-256444-grw5s2pf	614	4	consistent	consistent	JJ
cord-256444-grw5s2pf	614	5	with	with	IN
cord-256444-grw5s2pf	614	6	the	the	DT
cord-256444-grw5s2pf	614	7	finding	finding	NN
cord-256444-grw5s2pf	614	8	that	that	IN
cord-256444-grw5s2pf	614	9	the	the	DT
cord-256444-grw5s2pf	614	10	optimum	optimum	JJ
cord-256444-grw5s2pf	614	11	pH	ph	NN
cord-256444-grw5s2pf	614	12	for	for	IN
cord-256444-grw5s2pf	614	13	MHVinduced	MHVinduced	NNP
cord-256444-grw5s2pf	614	14	cell	cell	NN
cord-256444-grw5s2pf	614	15	fusion	fusion	NN
cord-256444-grw5s2pf	614	16	is	be	VBZ
cord-256444-grw5s2pf	614	17	7.4	7.4	CD
cord-256444-grw5s2pf	614	18	(	(	-LRB-
cord-256444-grw5s2pf	614	19	Weismiller	Weismiller	NNP
cord-256444-grw5s2pf	614	20	et	et	NNP
cord-256444-grw5s2pf	614	21	al	al	NNP
cord-256444-grw5s2pf	614	22	.	.	NNP
cord-256444-grw5s2pf	614	23	,	,	,
cord-256444-grw5s2pf	614	24	1990	1990	CD
cord-256444-grw5s2pf	614	25	;	;	:
cord-256444-grw5s2pf	614	26	Kooi	Kooi	NNP
cord-256444-grw5s2pf	614	27	et	et	NNP
cord-256444-grw5s2pf	614	28	al	al	NNP
cord-256444-grw5s2pf	614	29	.	.	NNP
cord-256444-grw5s2pf	614	30	,	,	,
cord-256444-grw5s2pf	614	31	19911	19911	CD
cord-256444-grw5s2pf	614	32	,	,	,
cord-256444-grw5s2pf	614	33	rather	rather	RB
cord-256444-grw5s2pf	614	34	than	than	IN
cord-256444-grw5s2pf	614	35	the	the	DT
cord-256444-grw5s2pf	614	36	acidic	acidic	JJ
cord-256444-grw5s2pf	614	37	pH	pH	NNP
cord-256444-grw5s2pf	614	38	expected	expect	VBN
cord-256444-grw5s2pf	614	39	for	for	IN
cord-256444-grw5s2pf	614	40	a	a	DT
cord-256444-grw5s2pf	614	41	virus	virus	NN
cord-256444-grw5s2pf	614	42	that	that	WDT
cord-256444-grw5s2pf	614	43	enters	enter	VBZ
cord-256444-grw5s2pf	614	44	cells	cell	NNS
cord-256444-grw5s2pf	614	45	by	by	IN
cord-256444-grw5s2pf	614	46	an	an	DT
cord-256444-grw5s2pf	614	47	endocytotic	endocytotic	JJ
cord-256444-grw5s2pf	614	48	pathway	pathway	NN
cord-256444-grw5s2pf	614	49	(	(	-LRB-
cord-256444-grw5s2pf	614	50	e.g.	e.g.	RB
cord-256444-grw5s2pf	614	51	,	,	,
cord-256444-grw5s2pf	614	52	vesicular	vesicular	JJ
cord-256444-grw5s2pf	614	53	stomatitis	stomatitis	NN
cord-256444-grw5s2pf	614	54	virus	virus	NN
cord-256444-grw5s2pf	614	55	)	)	-RRB-
cord-256444-grw5s2pf	614	56	.	.	.
cord-256444-grw5s2pf	615	1	The	the	DT
cord-256444-grw5s2pf	615	2	optimum	optimum	JJ
cord-256444-grw5s2pf	615	3	pH	ph	NN
cord-256444-grw5s2pf	615	4	for	for	IN
cord-256444-grw5s2pf	615	5	BCV	BCV	NNP
cord-256444-grw5s2pf	615	6	-	-	:
cord-256444-grw5s2pf	615	7	and	and	CC
cord-256444-grw5s2pf	615	8	IBV	IBV	NNP
cord-256444-grw5s2pf	615	9	-	-	HYPH
cord-256444-grw5s2pf	615	10	induced	induce	VBN
cord-256444-grw5s2pf	615	11	cell	cell	NN
cord-256444-grw5s2pf	615	12	fusion	fusion	NN
cord-256444-grw5s2pf	615	13	is	be	VBZ
cord-256444-grw5s2pf	615	14	also	also	RB
cord-256444-grw5s2pf	615	15	neutral	neutral	JJ
cord-256444-grw5s2pf	615	16	(	(	-LRB-
cord-256444-grw5s2pf	616	1	Payne	Payne	NNP
cord-256444-grw5s2pf	616	2	and	and	CC
cord-256444-grw5s2pf	616	3	Storz	Storz	NNP
cord-256444-grw5s2pf	616	4	,	,	,
cord-256444-grw5s2pf	616	5	1988	1988	CD
cord-256444-grw5s2pf	616	6	;	;	:
cord-256444-grw5s2pf	616	7	Li	Li	NNP
cord-256444-grw5s2pf	616	8	and	and	CC
cord-256444-grw5s2pf	616	9	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	616	10	,	,	,
cord-256444-grw5s2pf	616	11	1992	1992	CD
cord-256444-grw5s2pf	616	12	)	)	-RRB-
cord-256444-grw5s2pf	616	13	.	.	.
cord-256444-grw5s2pf	617	1	These	these	DT
cord-256444-grw5s2pf	617	2	findings	finding	NNS
cord-256444-grw5s2pf	617	3	suggest	suggest	VBP
cord-256444-grw5s2pf	617	4	that	that	IN
cord-256444-grw5s2pf	617	5	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	617	6	enters	enter	VBZ
cord-256444-grw5s2pf	617	7	cells	cell	NNS
cord-256444-grw5s2pf	617	8	by	by	IN
cord-256444-grw5s2pf	617	9	virus	virus	NN
cord-256444-grw5s2pf	617	10	-	-	HYPH
cord-256444-grw5s2pf	617	11	cell	cell	NN
cord-256444-grw5s2pf	617	12	fusion	fusion	NN
cord-256444-grw5s2pf	617	13	at	at	IN
cord-256444-grw5s2pf	617	14	the	the	DT
cord-256444-grw5s2pf	617	15	plasma	plasma	NN
cord-256444-grw5s2pf	617	16	membrane	membrane	NN
cord-256444-grw5s2pf	617	17	.	.	.
cord-256444-grw5s2pf	618	1	On	on	IN
cord-256444-grw5s2pf	618	2	the	the	DT
cord-256444-grw5s2pf	618	3	other	other	JJ
cord-256444-grw5s2pf	618	4	hand	hand	NN
cord-256444-grw5s2pf	618	5	,	,	,
cord-256444-grw5s2pf	618	6	virus	virus	NN
cord-256444-grw5s2pf	618	7	internalization	internalization	NN
cord-256444-grw5s2pf	618	8	by	by	IN
cord-256444-grw5s2pf	618	9	endocytosis	endocytosis	NN
cord-256444-grw5s2pf	618	10	may	may	MD
cord-256444-grw5s2pf	618	11	be	be	VB
cord-256444-grw5s2pf	618	12	a	a	DT
cord-256444-grw5s2pf	618	13	nonproductive	nonproductive	JJ
cord-256444-grw5s2pf	618	14	mechanism	mechanism	NN
cord-256444-grw5s2pf	618	15	which	which	WDT
cord-256444-grw5s2pf	618	16	does	do	VBZ
cord-256444-grw5s2pf	618	17	not	not	RB
cord-256444-grw5s2pf	618	18	depend	depend	VB
cord-256444-grw5s2pf	618	19	on	on	IN
cord-256444-grw5s2pf	618	20	virus	virus	NN
cord-256444-grw5s2pf	618	21	-	-	HYPH
cord-256444-grw5s2pf	618	22	receptor	receptor	NN
cord-256444-grw5s2pf	618	23	interaction	interaction	NN
cord-256444-grw5s2pf	618	24	,	,	,
cord-256444-grw5s2pf	618	25	since	since	IN
cord-256444-grw5s2pf	618	26	some	some	DT
cord-256444-grw5s2pf	618	27	MHV	mhv	NN
cord-256444-grw5s2pf	618	28	-	-	HYPH
cord-256444-grw5s2pf	618	29	resistant	resistant	JJ
cord-256444-grw5s2pf	618	30	cell	cell	NN
cord-256444-grw5s2pf	618	31	lines	line	NNS
cord-256444-grw5s2pf	618	32	can	can	MD
cord-256444-grw5s2pf	618	33	internalize	internalize	VB
cord-256444-grw5s2pf	618	34	MHV	MHV	NNP
cord-256444-grw5s2pf	618	35	particles	particle	NNS
cord-256444-grw5s2pf	618	36	as	as	RB
cord-256444-grw5s2pf	618	37	efficiently	efficiently	RB
cord-256444-grw5s2pf	618	38	as	as	IN
cord-256444-grw5s2pf	618	39	susceptible	susceptible	JJ
cord-256444-grw5s2pf	618	40	cell	cell	NN
cord-256444-grw5s2pf	618	41	lines	line	NNS
cord-256444-grw5s2pf	618	42	(	(	-LRB-
cord-256444-grw5s2pf	618	43	Kooi	Kooi	NNP
cord-256444-grw5s2pf	618	44	et	et	NNP
cord-256444-grw5s2pf	618	45	al	al	NNP
cord-256444-grw5s2pf	618	46	.	.	NNP
cord-256444-grw5s2pf	618	47	,	,	,
cord-256444-grw5s2pf	618	48	1991	1991	CD
cord-256444-grw5s2pf	618	49	)	)	-RRB-
cord-256444-grw5s2pf	618	50	.	.	.
cord-256444-grw5s2pf	619	1	Most	most	RBS
cord-256444-grw5s2pf	619	2	surprisingly	surprisingly	RB
cord-256444-grw5s2pf	619	3	,	,	,
cord-256444-grw5s2pf	619	4	even	even	RB
cord-256444-grw5s2pf	619	5	Vero	Vero	NNP
cord-256444-grw5s2pf	619	6	cells	cell	NNS
cord-256444-grw5s2pf	619	7	,	,	,
cord-256444-grw5s2pf	619	8	an	an	DT
cord-256444-grw5s2pf	619	9	African	african	JJ
cord-256444-grw5s2pf	619	10	monkey	monkey	NN
cord-256444-grw5s2pf	619	11	kidney	kidney	NN
cord-256444-grw5s2pf	619	12	cell	cell	NN
cord-256444-grw5s2pf	619	13	line	line	NN
cord-256444-grw5s2pf	619	14	which	which	WDT
cord-256444-grw5s2pf	619	15	presumably	presumably	RB
cord-256444-grw5s2pf	619	16	does	do	VBZ
cord-256444-grw5s2pf	619	17	not	not	RB
cord-256444-grw5s2pf	619	18	have	have	VB
cord-256444-grw5s2pf	619	19	an	an	DT
cord-256444-grw5s2pf	619	20	MHV	MHV	NNP
cord-256444-grw5s2pf	619	21	receptor	receptor	NN
cord-256444-grw5s2pf	619	22	,	,	,
cord-256444-grw5s2pf	619	23	can	can	MD
cord-256444-grw5s2pf	619	24	internalize	internalize	VB
cord-256444-grw5s2pf	619	25	virus	virus	NN
cord-256444-grw5s2pf	619	26	(	(	-LRB-
cord-256444-grw5s2pf	619	27	Kooi	Kooi	NNP
cord-256444-grw5s2pf	619	28	et	et	NNP
cord-256444-grw5s2pf	619	29	al	al	NNP
cord-256444-grw5s2pf	619	30	.	.	NNP
cord-256444-grw5s2pf	619	31	,	,	,
cord-256444-grw5s2pf	619	32	1991	1991	CD
cord-256444-grw5s2pf	619	33	)	)	-RRB-
cord-256444-grw5s2pf	619	34	.	.	.
cord-256444-grw5s2pf	620	1	Therefore	therefore	RB
cord-256444-grw5s2pf	620	2	,	,	,
cord-256444-grw5s2pf	620	3	it	-PRON-	PRP
cord-256444-grw5s2pf	620	4	is	be	VBZ
cord-256444-grw5s2pf	620	5	likely	likely	JJ
cord-256444-grw5s2pf	620	6	that	that	IN
cord-256444-grw5s2pf	620	7	MHV	MHV	NNP
cord-256444-grw5s2pf	620	8	enters	enter	VBZ
cord-256444-grw5s2pf	620	9	cells	cell	NNS
cord-256444-grw5s2pf	620	10	by	by	IN
cord-256444-grw5s2pf	620	11	both	both	DT
cord-256444-grw5s2pf	620	12	acidic	acidic	JJ
cord-256444-grw5s2pf	620	13	-	-	HYPH
cord-256444-grw5s2pf	620	14	pHdependent	pHdependent	NNP
cord-256444-grw5s2pf	620	15	(	(	-LRB-
cord-256444-grw5s2pf	620	16	endocytosis	endocytosis	NN
cord-256444-grw5s2pf	620	17	)	)	-RRB-
cord-256444-grw5s2pf	620	18	and	and	CC
cord-256444-grw5s2pf	620	19	-nondependent	-nondependent	JJ
cord-256444-grw5s2pf	620	20	pathways	pathway	NNS
cord-256444-grw5s2pf	621	1	(	(	-LRB-
cord-256444-grw5s2pf	621	2	Kooi	Kooi	NNP
cord-256444-grw5s2pf	621	3	et	et	NNP
cord-256444-grw5s2pf	621	4	al	al	NNP
cord-256444-grw5s2pf	621	5	.	.	NNP
cord-256444-grw5s2pf	621	6	,	,	,
cord-256444-grw5s2pf	621	7	1991	1991	CD
cord-256444-grw5s2pf	621	8	)	)	-RRB-
cord-256444-grw5s2pf	621	9	.	.	.
cord-256444-grw5s2pf	622	1	The	the	DT
cord-256444-grw5s2pf	622	2	exact	exact	JJ
cord-256444-grw5s2pf	622	3	mechanism	mechanism	NN
cord-256444-grw5s2pf	622	4	of	of	IN
cord-256444-grw5s2pf	622	5	virus	virus	NN
cord-256444-grw5s2pf	622	6	entry	entry	NN
cord-256444-grw5s2pf	622	7	may	may	MD
cord-256444-grw5s2pf	622	8	depend	depend	VB
cord-256444-grw5s2pf	622	9	on	on	IN
cord-256444-grw5s2pf	622	10	cell	cell	NN
cord-256444-grw5s2pf	622	11	types	type	NNS
cord-256444-grw5s2pf	622	12	and	and	CC
cord-256444-grw5s2pf	622	13	virus	virus	NN
cord-256444-grw5s2pf	622	14	strains	strain	NNS
cord-256444-grw5s2pf	622	15	.	.	.
cord-256444-grw5s2pf	623	1	Interestingly	interestingly	RB
cord-256444-grw5s2pf	623	2	,	,	,
cord-256444-grw5s2pf	623	3	an	an	DT
cord-256444-grw5s2pf	623	4	MHV	MHV	NNP
cord-256444-grw5s2pf	623	5	variant	variant	NN
cord-256444-grw5s2pf	623	6	which	which	WDT
cord-256444-grw5s2pf	623	7	has	have	VBZ
cord-256444-grw5s2pf	623	8	mutations	mutation	NNS
cord-256444-grw5s2pf	623	9	in	in	IN
cord-256444-grw5s2pf	623	10	the	the	DT
cord-256444-grw5s2pf	623	11	S	S	NNP
cord-256444-grw5s2pf	623	12	protein	protein	NN
cord-256444-grw5s2pf	623	13	has	have	VBZ
cord-256444-grw5s2pf	623	14	an	an	DT
cord-256444-grw5s2pf	623	15	acidic	acidic	JJ
cord-256444-grw5s2pf	623	16	optimum	optimum	JJ
cord-256444-grw5s2pf	623	17	pH	ph	NN
cord-256444-grw5s2pf	623	18	of	of	IN
cord-256444-grw5s2pf	623	19	5.5	5.5	CD
cord-256444-grw5s2pf	623	20	-	-	HYPH
cord-256444-grw5s2pf	623	21	6.0	6.0	CD
cord-256444-grw5s2pf	623	22	,	,	,
cord-256444-grw5s2pf	623	23	in	in	IN
cord-256444-grw5s2pf	623	24	contrast	contrast	NN
cord-256444-grw5s2pf	623	25	to	to	IN
cord-256444-grw5s2pf	623	26	the	the	DT
cord-256444-grw5s2pf	623	27	pH	pH	NNP
cord-256444-grw5s2pf	623	28	of	of	IN
cord-256444-grw5s2pf	623	29	7.5	7.5	CD
cord-256444-grw5s2pf	623	30	for	for	IN
cord-256444-grw5s2pf	623	31	the	the	DT
cord-256444-grw5s2pf	623	32	parental	parental	JJ
cord-256444-grw5s2pf	623	33	virus	virus	NN
cord-256444-grw5s2pf	623	34	(	(	-LRB-
cord-256444-grw5s2pf	623	35	Gallagher	Gallagher	NNP
cord-256444-grw5s2pf	623	36	et	et	NNP
cord-256444-grw5s2pf	623	37	al	al	NNP
cord-256444-grw5s2pf	623	38	.	.	NNP
cord-256444-grw5s2pf	623	39	,	,	,
cord-256444-grw5s2pf	623	40	1991	1991	CD
cord-256444-grw5s2pf	623	41	)	)	-RRB-
cord-256444-grw5s2pf	623	42	.	.	.
cord-256444-grw5s2pf	624	1	This	this	DT
cord-256444-grw5s2pf	624	2	virus	virus	NN
cord-256444-grw5s2pf	624	3	variant	variant	NN
cord-256444-grw5s2pf	624	4	probably	probably	RB
cord-256444-grw5s2pf	624	5	enters	enter	VBZ
cord-256444-grw5s2pf	624	6	cells	cell	NNS
cord-256444-grw5s2pf	624	7	by	by	IN
cord-256444-grw5s2pf	624	8	an	an	DT
cord-256444-grw5s2pf	624	9	endocytic	endocytic	JJ
cord-256444-grw5s2pf	624	10	pathway	pathway	NN
cord-256444-grw5s2pf	624	11	,	,	,
cord-256444-grw5s2pf	624	12	a	a	DT
cord-256444-grw5s2pf	624	13	fact	fact	NN
cord-256444-grw5s2pf	624	14	supported	support	VBN
cord-256444-grw5s2pf	624	15	by	by	IN
cord-256444-grw5s2pf	624	16	the	the	DT
cord-256444-grw5s2pf	624	17	finding	finding	NN
cord-256444-grw5s2pf	624	18	that	that	IN
cord-256444-grw5s2pf	624	19	infection	infection	NN
cord-256444-grw5s2pf	624	20	of	of	IN
cord-256444-grw5s2pf	624	21	this	this	DT
cord-256444-grw5s2pf	624	22	variant	variant	JJ
cord-256444-grw5s2pf	624	23	virus	virus	NN
cord-256444-grw5s2pf	624	24	is	be	VBZ
cord-256444-grw5s2pf	624	25	inhibited	inhibit	VBN
cord-256444-grw5s2pf	624	26	by	by	IN
cord-256444-grw5s2pf	624	27	ammonium	ammonium	NN
cord-256444-grw5s2pf	624	28	chloride	chloride	NN
cord-256444-grw5s2pf	624	29	or	or	CC
cord-256444-grw5s2pf	624	30	chloroquine	chloroquine	NN
cord-256444-grw5s2pf	624	31	.	.	.
cord-256444-grw5s2pf	625	1	What	what	WP
cord-256444-grw5s2pf	625	2	triggers	trigger	VBZ
cord-256444-grw5s2pf	625	3	virus	virus	NN
cord-256444-grw5s2pf	625	4	internalization	internalization	NN
cord-256444-grw5s2pf	625	5	after	after	IN
cord-256444-grw5s2pf	625	6	virus	virus	NN
cord-256444-grw5s2pf	625	7	-	-	HYPH
cord-256444-grw5s2pf	625	8	receptor	receptor	NN
cord-256444-grw5s2pf	625	9	binding	binding	NN
cord-256444-grw5s2pf	625	10	is	be	VBZ
cord-256444-grw5s2pf	625	11	not	not	RB
cord-256444-grw5s2pf	625	12	clear	clear	JJ
cord-256444-grw5s2pf	625	13	.	.	.
cord-256444-grw5s2pf	626	1	It	-PRON-	PRP
cord-256444-grw5s2pf	626	2	has	have	VBZ
cord-256444-grw5s2pf	626	3	been	be	VBN
cord-256444-grw5s2pf	626	4	shown	show	VBN
cord-256444-grw5s2pf	626	5	that	that	IN
cord-256444-grw5s2pf	626	6	a	a	DT
cord-256444-grw5s2pf	626	7	conformational	conformational	JJ
cord-256444-grw5s2pf	626	8	change	change	NN
cord-256444-grw5s2pf	626	9	in	in	IN
cord-256444-grw5s2pf	626	10	the	the	DT
cord-256444-grw5s2pf	626	11	S	S	NNP
cord-256444-grw5s2pf	626	12	protein	protein	NN
cord-256444-grw5s2pf	626	13	could	could	MD
cord-256444-grw5s2pf	626	14	be	be	VB
cord-256444-grw5s2pf	626	15	induced	induce	VBN
cord-256444-grw5s2pf	626	16	at	at	IN
cord-256444-grw5s2pf	626	17	pH	pH	NNP
cord-256444-grw5s2pf	626	18	8.0	8.0	CD
cord-256444-grw5s2pf	626	19	and	and	CC
cord-256444-grw5s2pf	626	20	incubation	incubation	NN
cord-256444-grw5s2pf	626	21	at	at	IN
cord-256444-grw5s2pf	626	22	37	37	CD
cord-256444-grw5s2pf	626	23	°	°	NN
cord-256444-grw5s2pf	626	24	C	c	NN
cord-256444-grw5s2pf	626	25	.	.	.
cord-256444-grw5s2pf	627	1	Whether	whether	IN
cord-256444-grw5s2pf	627	2	this	this	DT
cord-256444-grw5s2pf	627	3	represents	represent	VBZ
cord-256444-grw5s2pf	627	4	the	the	DT
cord-256444-grw5s2pf	627	5	expected	expect	VBN
cord-256444-grw5s2pf	627	6	conformational	conformational	JJ
cord-256444-grw5s2pf	627	7	change	change	NN
cord-256444-grw5s2pf	627	8	following	follow	VBG
cord-256444-grw5s2pf	627	9	virus	virus	NN
cord-256444-grw5s2pf	627	10	-	-	HYPH
cord-256444-grw5s2pf	627	11	receptor	receptor	NN
cord-256444-grw5s2pf	627	12	binding	binding	NN
cord-256444-grw5s2pf	627	13	is	be	VBZ
cord-256444-grw5s2pf	627	14	not	not	RB
cord-256444-grw5s2pf	627	15	clear	clear	JJ
cord-256444-grw5s2pf	627	16	.	.	.
cord-256444-grw5s2pf	628	1	Irrespective	irrespective	RB
cord-256444-grw5s2pf	628	2	of	of	IN
cord-256444-grw5s2pf	628	3	the	the	DT
cord-256444-grw5s2pf	628	4	mechanism	mechanism	NN
cord-256444-grw5s2pf	628	5	of	of	IN
cord-256444-grw5s2pf	628	6	virus	virus	NN
cord-256444-grw5s2pf	628	7	internalization	internalization	NN
cord-256444-grw5s2pf	628	8	,	,	,
cord-256444-grw5s2pf	628	9	fusion	fusion	NN
cord-256444-grw5s2pf	628	10	between	between	IN
cord-256444-grw5s2pf	628	11	the	the	DT
cord-256444-grw5s2pf	628	12	viral	viral	JJ
cord-256444-grw5s2pf	628	13	envelope	envelope	NN
cord-256444-grw5s2pf	628	14	and	and	CC
cord-256444-grw5s2pf	628	15	cell	cell	NN
cord-256444-grw5s2pf	628	16	membrane	membrane	NN
cord-256444-grw5s2pf	628	17	must	must	MD
cord-256444-grw5s2pf	628	18	occur	occur	VB
cord-256444-grw5s2pf	628	19	,	,	,
cord-256444-grw5s2pf	628	20	either	either	CC
cord-256444-grw5s2pf	628	21	at	at	IN
cord-256444-grw5s2pf	628	22	the	the	DT
cord-256444-grw5s2pf	628	23	cell	cell	NN
cord-256444-grw5s2pf	628	24	surface	surface	NN
cord-256444-grw5s2pf	628	25	or	or	CC
cord-256444-grw5s2pf	628	26	in	in	IN
cord-256444-grw5s2pf	628	27	the	the	DT
cord-256444-grw5s2pf	628	28	endosome	endosome	NN
cord-256444-grw5s2pf	628	29	,	,	,
cord-256444-grw5s2pf	628	30	for	for	IN
cord-256444-grw5s2pf	628	31	viral	viral	JJ
cord-256444-grw5s2pf	628	32	infection	infection	NN
cord-256444-grw5s2pf	628	33	to	to	TO
cord-256444-grw5s2pf	628	34	take	take	VB
cord-256444-grw5s2pf	628	35	place	place	NN
cord-256444-grw5s2pf	628	36	.	.	.
cord-256444-grw5s2pf	629	1	Virus	virus	NN
cord-256444-grw5s2pf	629	2	-	-	HYPH
cord-256444-grw5s2pf	629	3	induced	induce	VBN
cord-256444-grw5s2pf	629	4	cell	cell	NN
cord-256444-grw5s2pf	629	5	-	-	HYPH
cord-256444-grw5s2pf	629	6	cell	cell	NN
cord-256444-grw5s2pf	629	7	fusion	fusion	NN
cord-256444-grw5s2pf	629	8	has	have	VBZ
cord-256444-grw5s2pf	629	9	been	be	VBN
cord-256444-grw5s2pf	629	10	used	use	VBN
cord-256444-grw5s2pf	629	11	to	to	TO
cord-256444-grw5s2pf	629	12	investigate	investigate	VB
cord-256444-grw5s2pf	629	13	the	the	DT
cord-256444-grw5s2pf	629	14	ability	ability	NN
cord-256444-grw5s2pf	629	15	of	of	IN
cord-256444-grw5s2pf	629	16	a	a	DT
cord-256444-grw5s2pf	629	17	virus	virus	NN
cord-256444-grw5s2pf	629	18	to	to	TO
cord-256444-grw5s2pf	629	19	induce	induce	VB
cord-256444-grw5s2pf	629	20	fusion	fusion	NN
cord-256444-grw5s2pf	629	21	.	.	.
cord-256444-grw5s2pf	630	1	Early	early	JJ
cord-256444-grw5s2pf	630	2	studies	study	NNS
cord-256444-grw5s2pf	630	3	with	with	IN
cord-256444-grw5s2pf	630	4	MHV	MHV	NNP
cord-256444-grw5s2pf	630	5	indicated	indicate	VBD
cord-256444-grw5s2pf	630	6	that	that	IN
cord-256444-grw5s2pf	630	7	virus	virus	NN
cord-256444-grw5s2pf	630	8	-	-	HYPH
cord-256444-grw5s2pf	630	9	induced	induce	VBN
cord-256444-grw5s2pf	630	10	fusion	fusion	NN
cord-256444-grw5s2pf	630	11	from	from	IN
cord-256444-grw5s2pf	630	12	without	without	IN
cord-256444-grw5s2pf	630	13	(	(	-LRB-
cord-256444-grw5s2pf	630	14	caused	cause	VBN
cord-256444-grw5s2pf	630	15	by	by	IN
cord-256444-grw5s2pf	630	16	virions	virion	NNS
cord-256444-grw5s2pf	630	17	at	at	IN
cord-256444-grw5s2pf	630	18	the	the	DT
cord-256444-grw5s2pf	630	19	cell	cell	NN
cord-256444-grw5s2pf	630	20	surface	surface	NN
cord-256444-grw5s2pf	630	21	)	)	-RRB-
cord-256444-grw5s2pf	630	22	or	or	CC
cord-256444-grw5s2pf	630	23	fusion	fusion	NN
cord-256444-grw5s2pf	630	24	from	from	IN
cord-256444-grw5s2pf	630	25	within	within	IN
cord-256444-grw5s2pf	630	26	(	(	-LRB-
cord-256444-grw5s2pf	630	27	caused	cause	VBN
cord-256444-grw5s2pf	630	28	by	by	IN
cord-256444-grw5s2pf	630	29	de	de	NNP
cord-256444-grw5s2pf	630	30	~O	~O	NNP
cord-256444-grw5s2pf	630	31	U	u	NN
cord-256444-grw5s2pf	630	32	O	o	NN
cord-256444-grw5s2pf	630	33	synthesized	synthesize	VBN
cord-256444-grw5s2pf	630	34	S	S	NNP
cord-256444-grw5s2pf	630	35	protein	protein	NN
cord-256444-grw5s2pf	630	36	on	on	IN
cord-256444-grw5s2pf	630	37	the	the	DT
cord-256444-grw5s2pf	630	38	cell	cell	NN
cord-256444-grw5s2pf	630	39	surface	surface	NN
cord-256444-grw5s2pf	630	40	)	)	-RRB-
cord-256444-grw5s2pf	630	41	required	require	VBN
cord-256444-grw5s2pf	630	42	cleavage	cleavage	NN
cord-256444-grw5s2pf	630	43	of	of	IN
cord-256444-grw5s2pf	630	44	the	the	DT
cord-256444-grw5s2pf	630	45	S	S	NNP
cord-256444-grw5s2pf	630	46	protein	protein	NN
cord-256444-grw5s2pf	630	47	(	(	-LRB-
cord-256444-grw5s2pf	630	48	Frana	Frana	NNP
cord-256444-grw5s2pf	630	49	et	et	FW
cord-256444-grw5s2pf	630	50	al	al	NNP
cord-256444-grw5s2pf	630	51	.	.	NNP
cord-256444-grw5s2pf	630	52	,	,	,
cord-256444-grw5s2pf	630	53	1985	1985	CD
cord-256444-grw5s2pf	630	54	;	;	:
cord-256444-grw5s2pf	630	55	Sturman	Sturman	NNP
cord-256444-grw5s2pf	630	56	et	et	NNP
cord-256444-grw5s2pf	630	57	al	al	NNP
cord-256444-grw5s2pf	630	58	.	.	NNP
cord-256444-grw5s2pf	630	59	,	,	,
cord-256444-grw5s2pf	630	60	1985	1985	CD
cord-256444-grw5s2pf	630	61	)	)	-RRB-
cord-256444-grw5s2pf	630	62	.	.	.
cord-256444-grw5s2pf	631	1	Work	work	VB
cord-256444-grw5s2pf	631	2	on	on	IN
cord-256444-grw5s2pf	631	3	BCV	BCV	NNP
cord-256444-grw5s2pf	631	4	supported	support	VBD
cord-256444-grw5s2pf	631	5	this	this	DT
cord-256444-grw5s2pf	631	6	view	view	NN
cord-256444-grw5s2pf	631	7	(	(	-LRB-
cord-256444-grw5s2pf	631	8	Payne	Payne	NNP
cord-256444-grw5s2pf	631	9	and	and	CC
cord-256444-grw5s2pf	631	10	Storz	Storz	NNP
cord-256444-grw5s2pf	631	11	,	,	,
cord-256444-grw5s2pf	631	12	1988	1988	CD
cord-256444-grw5s2pf	631	13	;	;	:
cord-256444-grw5s2pf	631	14	Storz	Storz	NNP
cord-256444-grw5s2pf	631	15	et	et	NNP
cord-256444-grw5s2pf	631	16	al	al	NNP
cord-256444-grw5s2pf	631	17	.	.	NNP
cord-256444-grw5s2pf	631	18	,	,	,
cord-256444-grw5s2pf	631	19	1991	1991	CD
cord-256444-grw5s2pf	631	20	)	)	-RRB-
cord-256444-grw5s2pf	631	21	.	.	.
cord-256444-grw5s2pf	632	1	However	however	RB
cord-256444-grw5s2pf	632	2	,	,	,
cord-256444-grw5s2pf	632	3	more	more	JJR
cord-256444-grw5s2pf	632	4	recent	recent	JJ
cord-256444-grw5s2pf	632	5	experiments	experiment	NNS
cord-256444-grw5s2pf	632	6	involving	involve	VBG
cord-256444-grw5s2pf	632	7	the	the	DT
cord-256444-grw5s2pf	632	8	expression	expression	NN
cord-256444-grw5s2pf	632	9	of	of	IN
cord-256444-grw5s2pf	632	10	S	S	NNP
cord-256444-grw5s2pf	632	11	protein	protein	NN
cord-256444-grw5s2pf	632	12	(	(	-LRB-
cord-256444-grw5s2pf	632	13	de	de	FW
cord-256444-grw5s2pf	632	14	Groot	Groot	NNP
cord-256444-grw5s2pf	632	15	et	et	FW
cord-256444-grw5s2pf	632	16	al	al	NNP
cord-256444-grw5s2pf	632	17	.	.	NNP
cord-256444-grw5s2pf	632	18	,	,	,
cord-256444-grw5s2pf	632	19	1989	1989	CD
cord-256444-grw5s2pf	632	20	;	;	:
cord-256444-grw5s2pf	632	21	Stauber	Stauber	NNP
cord-256444-grw5s2pf	632	22	et	et	NNP
cord-256444-grw5s2pf	632	23	al	al	NNP
cord-256444-grw5s2pf	632	24	.	.	NNP
cord-256444-grw5s2pf	632	25	,	,	,
cord-256444-grw5s2pf	632	26	1993	1993	CD
cord-256444-grw5s2pf	632	27	;	;	:
cord-256444-grw5s2pf	632	28	Taguchi	Taguchi	NNP
cord-256444-grw5s2pf	632	29	,	,	,
cord-256444-grw5s2pf	632	30	1993	1993	CD
cord-256444-grw5s2pf	632	31	)	)	-RRB-
cord-256444-grw5s2pf	632	32	and	and	CC
cord-256444-grw5s2pf	632	33	studies	study	NNS
cord-256444-grw5s2pf	632	34	of	of	IN
cord-256444-grw5s2pf	632	35	MHV	MHV	NNP
cord-256444-grw5s2pf	632	36	fusion	fusion	NN
cord-256444-grw5s2pf	632	37	mutants	mutant	NNS
cord-256444-grw5s2pf	632	38	(	(	-LRB-
cord-256444-grw5s2pf	632	39	Gombold	Gombold	NNP
cord-256444-grw5s2pf	632	40	et	et	NNP
cord-256444-grw5s2pf	632	41	al	al	NNP
cord-256444-grw5s2pf	632	42	.	.	NNP
cord-256444-grw5s2pf	632	43	,	,	,
cord-256444-grw5s2pf	632	44	1993	1993	CD
cord-256444-grw5s2pf	632	45	)	)	-RRB-
cord-256444-grw5s2pf	632	46	have	have	VBP
cord-256444-grw5s2pf	632	47	indicated	indicate	VBN
cord-256444-grw5s2pf	632	48	that	that	IN
cord-256444-grw5s2pf	632	49	uncleaved	uncleaved	NNP
cord-256444-grw5s2pf	632	50	S	S	NNP
cord-256444-grw5s2pf	632	51	can	can	MD
cord-256444-grw5s2pf	632	52	cause	cause	VB
cord-256444-grw5s2pf	632	53	syncytium	syncytium	NN
cord-256444-grw5s2pf	632	54	formation	formation	NN
cord-256444-grw5s2pf	632	55	,	,	,
cord-256444-grw5s2pf	632	56	though	though	IN
cord-256444-grw5s2pf	632	57	less	less	RBR
cord-256444-grw5s2pf	632	58	efficiently	efficiently	RB
cord-256444-grw5s2pf	632	59	than	than	IN
cord-256444-grw5s2pf	632	60	the	the	DT
cord-256444-grw5s2pf	632	61	cleaved	cleaved	JJ
cord-256444-grw5s2pf	632	62	S.	S.	NNP
cord-256444-grw5s2pf	632	63	Of	of	RB
cord-256444-grw5s2pf	632	64	course	course	NN
cord-256444-grw5s2pf	632	65	,	,	,
cord-256444-grw5s2pf	632	66	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	632	67	such	such	JJ
cord-256444-grw5s2pf	632	68	as	as	IN
cord-256444-grw5s2pf	632	69	TGEV	TGEV	NNP
cord-256444-grw5s2pf	632	70	,	,	,
cord-256444-grw5s2pf	632	71	which	which	WDT
cord-256444-grw5s2pf	632	72	have	have	VBP
cord-256444-grw5s2pf	632	73	no	no	DT
cord-256444-grw5s2pf	632	74	cleaved	cleave	VBN
cord-256444-grw5s2pf	632	75	S	S	NNP
cord-256444-grw5s2pf	632	76	protein	protein	NN
cord-256444-grw5s2pf	632	77	,	,	,
cord-256444-grw5s2pf	632	78	are	be	VBP
cord-256444-grw5s2pf	632	79	infectious	infectious	JJ
cord-256444-grw5s2pf	632	80	,	,	,
cord-256444-grw5s2pf	632	81	in	in	IN
cord-256444-grw5s2pf	632	82	fact	fact	NN
cord-256444-grw5s2pf	632	83	,	,	,
cord-256444-grw5s2pf	632	84	highly	highly	RB
cord-256444-grw5s2pf	632	85	so	so	RB
cord-256444-grw5s2pf	632	86	.	.	.
cord-256444-grw5s2pf	633	1	Since	since	IN
cord-256444-grw5s2pf	633	2	fusion	fusion	NN
cord-256444-grw5s2pf	633	3	of	of	IN
cord-256444-grw5s2pf	633	4	the	the	DT
cord-256444-grw5s2pf	633	5	virion	virion	NN
cord-256444-grw5s2pf	633	6	envelope	envelope	NN
cord-256444-grw5s2pf	633	7	with	with	IN
cord-256444-grw5s2pf	633	8	a	a	DT
cord-256444-grw5s2pf	633	9	cell	cell	NN
cord-256444-grw5s2pf	633	10	membrane	membrane	NN
cord-256444-grw5s2pf	633	11	is	be	VBZ
cord-256444-grw5s2pf	633	12	an	an	DT
cord-256444-grw5s2pf	633	13	essential	essential	JJ
cord-256444-grw5s2pf	633	14	part	part	NN
cord-256444-grw5s2pf	633	15	of	of	IN
cord-256444-grw5s2pf	633	16	the	the	DT
cord-256444-grw5s2pf	633	17	infection	infection	NN
cord-256444-grw5s2pf	633	18	process	process	NN
cord-256444-grw5s2pf	633	19	,	,	,
cord-256444-grw5s2pf	633	20	these	these	DT
cord-256444-grw5s2pf	633	21	results	result	NNS
cord-256444-grw5s2pf	633	22	suggest	suggest	VBP
cord-256444-grw5s2pf	633	23	that	that	IN
cord-256444-grw5s2pf	633	24	TGEV	TGEV	NNP
cord-256444-grw5s2pf	633	25	must	must	MD
cord-256444-grw5s2pf	633	26	be	be	VB
cord-256444-grw5s2pf	633	27	able	able	JJ
cord-256444-grw5s2pf	633	28	to	to	TO
cord-256444-grw5s2pf	633	29	cause	cause	VB
cord-256444-grw5s2pf	633	30	viruscell	viruscell	NNP
cord-256444-grw5s2pf	633	31	fusion	fusion	NN
cord-256444-grw5s2pf	633	32	.	.	.
cord-256444-grw5s2pf	634	1	Thus	thus	RB
cord-256444-grw5s2pf	634	2	,	,	,
cord-256444-grw5s2pf	634	3	virus	virus	NN
cord-256444-grw5s2pf	634	4	-	-	HYPH
cord-256444-grw5s2pf	634	5	cell	cell	NN
cord-256444-grw5s2pf	634	6	fusion	fusion	NN
cord-256444-grw5s2pf	634	7	and	and	CC
cord-256444-grw5s2pf	634	8	cell	cell	NN
cord-256444-grw5s2pf	634	9	-	-	HYPH
cord-256444-grw5s2pf	634	10	cell	cell	NN
cord-256444-grw5s2pf	634	11	fusion	fusion	NN
cord-256444-grw5s2pf	634	12	may	may	MD
cord-256444-grw5s2pf	634	13	have	have	VB
cord-256444-grw5s2pf	634	14	different	different	JJ
cord-256444-grw5s2pf	634	15	requirements	requirement	NNS
cord-256444-grw5s2pf	634	16	,	,	,
cord-256444-grw5s2pf	634	17	and	and	CC
cord-256444-grw5s2pf	634	18	,	,	,
cord-256444-grw5s2pf	634	19	for	for	IN
cord-256444-grw5s2pf	634	20	at	at	IN
cord-256444-grw5s2pf	634	21	least	least	JJS
cord-256444-grw5s2pf	634	22	some	some	DT
cord-256444-grw5s2pf	634	23	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	634	24	,	,	,
cord-256444-grw5s2pf	634	25	S	s	NN
cord-256444-grw5s2pf	634	26	cleavage	cleavage	NN
cord-256444-grw5s2pf	634	27	is	be	VBZ
cord-256444-grw5s2pf	634	28	not	not	RB
cord-256444-grw5s2pf	634	29	required	require	VBN
cord-256444-grw5s2pf	634	30	for	for	IN
cord-256444-grw5s2pf	634	31	the	the	DT
cord-256444-grw5s2pf	634	32	fusion	fusion	NN
cord-256444-grw5s2pf	634	33	of	of	IN
cord-256444-grw5s2pf	634	34	a	a	DT
cord-256444-grw5s2pf	634	35	virion	virion	NN
cord-256444-grw5s2pf	634	36	with	with	IN
cord-256444-grw5s2pf	634	37	a	a	DT
cord-256444-grw5s2pf	634	38	cell	cell	NN
cord-256444-grw5s2pf	634	39	membrane	membrane	NN
cord-256444-grw5s2pf	634	40	.	.	.
cord-256444-grw5s2pf	635	1	Nevertheless	nevertheless	RB
cord-256444-grw5s2pf	635	2	,	,	,
cord-256444-grw5s2pf	635	3	cleaved	cleaved	JJ
cord-256444-grw5s2pf	635	4	S	S	NNP
cord-256444-grw5s2pf	635	5	may	may	MD
cord-256444-grw5s2pf	635	6	be	be	VB
cord-256444-grw5s2pf	635	7	more	more	RBR
cord-256444-grw5s2pf	635	8	efficient	efficient	JJ
cord-256444-grw5s2pf	635	9	at	at	IN
cord-256444-grw5s2pf	635	10	inducing	induce	VBG
cord-256444-grw5s2pf	635	11	fusion	fusion	NN
cord-256444-grw5s2pf	635	12	for	for	IN
cord-256444-grw5s2pf	635	13	some	some	DT
cord-256444-grw5s2pf	635	14	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	635	15	.	.	.
cord-256444-grw5s2pf	636	1	The	the	DT
cord-256444-grw5s2pf	636	2	concentration	concentration	NN
cord-256444-grw5s2pf	636	3	of	of	IN
cord-256444-grw5s2pf	636	4	S	s	NN
cord-256444-grw5s2pf	636	5	at	at	IN
cord-256444-grw5s2pf	636	6	the	the	DT
cord-256444-grw5s2pf	636	7	surface	surface	NN
cord-256444-grw5s2pf	636	8	of	of	IN
cord-256444-grw5s2pf	636	9	a	a	DT
cord-256444-grw5s2pf	636	10	virion	virion	NN
cord-256444-grw5s2pf	636	11	may	may	MD
cord-256444-grw5s2pf	636	12	be	be	VB
cord-256444-grw5s2pf	636	13	higher	high	JJR
cord-256444-grw5s2pf	636	14	than	than	IN
cord-256444-grw5s2pf	636	15	at	at	IN
cord-256444-grw5s2pf	636	16	the	the	DT
cord-256444-grw5s2pf	636	17	cell	cell	NN
cord-256444-grw5s2pf	636	18	surface	surface	NN
cord-256444-grw5s2pf	636	19	,	,	,
cord-256444-grw5s2pf	636	20	such	such	JJ
cord-256444-grw5s2pf	636	21	that	that	IN
cord-256444-grw5s2pf	636	22	even	even	RB
cord-256444-grw5s2pf	636	23	the	the	DT
cord-256444-grw5s2pf	636	24	uncleaved	uncleaved	JJ
cord-256444-grw5s2pf	636	25	S	S	NNP
cord-256444-grw5s2pf	636	26	can	can	MD
cord-256444-grw5s2pf	636	27	induce	induce	VB
cord-256444-grw5s2pf	636	28	virion	virion	NN
cord-256444-grw5s2pf	636	29	-	-	HYPH
cord-256444-grw5s2pf	636	30	cell	cell	NN
cord-256444-grw5s2pf	636	31	fusion	fusion	NN
cord-256444-grw5s2pf	636	32	,	,	,
cord-256444-grw5s2pf	636	33	even	even	RB
cord-256444-grw5s2pf	636	34	though	though	IN
cord-256444-grw5s2pf	636	35	it	-PRON-	PRP
cord-256444-grw5s2pf	636	36	can	can	MD
cord-256444-grw5s2pf	636	37	not	not	RB
cord-256444-grw5s2pf	636	38	cause	cause	VB
cord-256444-grw5s2pf	636	39	cell	cell	NN
cord-256444-grw5s2pf	636	40	-	-	HYPH
cord-256444-grw5s2pf	636	41	cell	cell	NN
cord-256444-grw5s2pf	636	42	fusion	fusion	NN
cord-256444-grw5s2pf	636	43	.	.	.
cord-256444-grw5s2pf	637	1	Virusreceptor	virusreceptor	NN
cord-256444-grw5s2pf	637	2	interaction	interaction	NN
cord-256444-grw5s2pf	637	3	may	may	MD
cord-256444-grw5s2pf	637	4	also	also	RB
cord-256444-grw5s2pf	637	5	trigger	trigger	VB
cord-256444-grw5s2pf	637	6	a	a	DT
cord-256444-grw5s2pf	637	7	signal	signal	NN
cord-256444-grw5s2pf	637	8	transduction	transduction	NN
cord-256444-grw5s2pf	637	9	pathway	pathway	NN
cord-256444-grw5s2pf	637	10	to	to	TO
cord-256444-grw5s2pf	637	11	facilitate	facilitate	VB
cord-256444-grw5s2pf	637	12	the	the	DT
cord-256444-grw5s2pf	637	13	internalization	internalization	NN
cord-256444-grw5s2pf	637	14	of	of	IN
cord-256444-grw5s2pf	637	15	the	the	DT
cord-256444-grw5s2pf	637	16	virus	virus	NN
cord-256444-grw5s2pf	637	17	-	-	HYPH
cord-256444-grw5s2pf	637	18	receptor	receptor	NN
cord-256444-grw5s2pf	637	19	complex	complex	NN
cord-256444-grw5s2pf	637	20	.	.	.
cord-256444-grw5s2pf	638	1	One	one	CD
cord-256444-grw5s2pf	638	2	study	study	NN
cord-256444-grw5s2pf	638	3	showed	show	VBD
cord-256444-grw5s2pf	638	4	that	that	IN
cord-256444-grw5s2pf	638	5	tyrosine	tyrosine	NN
cord-256444-grw5s2pf	638	6	kinase	kinase	NN
cord-256444-grw5s2pf	638	7	is	be	VBZ
cord-256444-grw5s2pf	638	8	activated	activate	VBN
cord-256444-grw5s2pf	638	9	in	in	IN
cord-256444-grw5s2pf	638	10	macrophages	macrophage	NNS
cord-256444-grw5s2pf	638	11	immediately	immediately	RB
cord-256444-grw5s2pf	638	12	following	follow	VBG
cord-256444-grw5s2pf	638	13	MHV-3	MHV-3	NNP
cord-256444-grw5s2pf	638	14	infection	infection	NN
cord-256444-grw5s2pf	639	1	(	(	-LRB-
cord-256444-grw5s2pf	639	2	Dackiw	Dackiw	NNP
cord-256444-grw5s2pf	639	3	et	et	NNP
cord-256444-grw5s2pf	639	4	al	al	NNP
cord-256444-grw5s2pf	639	5	.	.	NNP
cord-256444-grw5s2pf	639	6	,	,	,
cord-256444-grw5s2pf	639	7	1995	1995	CD
cord-256444-grw5s2pf	639	8	)	)	-RRB-
cord-256444-grw5s2pf	639	9	.	.	.
cord-256444-grw5s2pf	640	1	It	-PRON-	PRP
cord-256444-grw5s2pf	640	2	is	be	VBZ
cord-256444-grw5s2pf	640	3	not	not	RB
cord-256444-grw5s2pf	640	4	yet	yet	RB
cord-256444-grw5s2pf	640	5	known	know	VBN
cord-256444-grw5s2pf	640	6	whether	whether	IN
cord-256444-grw5s2pf	640	7	this	this	DT
cord-256444-grw5s2pf	640	8	is	be	VBZ
cord-256444-grw5s2pf	640	9	required	require	VBN
cord-256444-grw5s2pf	640	10	for	for	IN
cord-256444-grw5s2pf	640	11	virus	virus	NN
cord-256444-grw5s2pf	640	12	entry	entry	NN
cord-256444-grw5s2pf	640	13	.	.	.
cord-256444-grw5s2pf	641	1	The	the	DT
cord-256444-grw5s2pf	641	2	mechanism	mechanism	NN
cord-256444-grw5s2pf	641	3	of	of	IN
cord-256444-grw5s2pf	641	4	virus	virus	NN
cord-256444-grw5s2pf	641	5	uncoating	uncoating	NN
cord-256444-grw5s2pf	641	6	,	,	,
cord-256444-grw5s2pf	641	7	i.e.	i.e.	FW
cord-256444-grw5s2pf	641	8	,	,	,
cord-256444-grw5s2pf	641	9	the	the	DT
cord-256444-grw5s2pf	641	10	release	release	NN
cord-256444-grw5s2pf	641	11	of	of	IN
cord-256444-grw5s2pf	641	12	virion	virion	NN
cord-256444-grw5s2pf	641	13	RNA	RNA	NNP
cord-256444-grw5s2pf	641	14	from	from	IN
cord-256444-grw5s2pf	641	15	the	the	DT
cord-256444-grw5s2pf	641	16	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	641	17	,	,	,
cord-256444-grw5s2pf	641	18	after	after	IN
cord-256444-grw5s2pf	641	19	the	the	DT
cord-256444-grw5s2pf	641	20	virus	virus	NN
cord-256444-grw5s2pf	641	21	has	have	VBZ
cord-256444-grw5s2pf	641	22	been	be	VBN
cord-256444-grw5s2pf	641	23	internalized	internalize	VBN
cord-256444-grw5s2pf	641	24	remains	remain	NNS
cord-256444-grw5s2pf	641	25	unclear	unclear	JJ
cord-256444-grw5s2pf	641	26	.	.	.
cord-256444-grw5s2pf	642	1	One	one	CD
cord-256444-grw5s2pf	642	2	study	study	NN
cord-256444-grw5s2pf	642	3	suggested	suggest	VBD
cord-256444-grw5s2pf	642	4	that	that	IN
cord-256444-grw5s2pf	642	5	virus	virus	NN
cord-256444-grw5s2pf	642	6	uncoating	uncoate	VBG
cord-256444-grw5s2pf	642	7	may	may	MD
cord-256444-grw5s2pf	642	8	involve	involve	VB
cord-256444-grw5s2pf	642	9	an	an	DT
cord-256444-grw5s2pf	642	10	endosomal	endosomal	NNP
cord-256444-grw5s2pf	642	11	neutral	neutral	JJ
cord-256444-grw5s2pf	642	12	phosphatase	phosphatase	NN
cord-256444-grw5s2pf	642	13	,	,	,
cord-256444-grw5s2pf	642	14	which	which	WDT
cord-256444-grw5s2pf	642	15	preferentially	preferentially	RB
cord-256444-grw5s2pf	642	16	dephosphorylates	dephosphorylate	VBZ
cord-256444-grw5s2pf	642	17	the	the	DT
cord-256444-grw5s2pf	642	18	nucleocapsid	nucleocapsid	NNP
cord-256444-grw5s2pf	642	19	protein	protein	NN
cord-256444-grw5s2pf	642	20	(	(	-LRB-
cord-256444-grw5s2pf	642	21	Mohandas	Mohandas	NNP
cord-256444-grw5s2pf	642	22	and	and	CC
cord-256444-grw5s2pf	642	23	Dales	Dales	NNP
cord-256444-grw5s2pf	642	24	,	,	,
cord-256444-grw5s2pf	642	25	1991	1991	CD
cord-256444-grw5s2pf	642	26	)	)	-RRB-
cord-256444-grw5s2pf	642	27	.	.	.
cord-256444-grw5s2pf	643	1	Furthermore	furthermore	RB
cord-256444-grw5s2pf	643	2	,	,	,
cord-256444-grw5s2pf	643	3	while	while	IN
cord-256444-grw5s2pf	643	4	immature	immature	JJ
cord-256444-grw5s2pf	643	5	oligodendrocytes	oligodendrocyte	NNS
cord-256444-grw5s2pf	643	6	were	be	VBD
cord-256444-grw5s2pf	643	7	sensitive	sensitive	JJ
cord-256444-grw5s2pf	643	8	to	to	IN
cord-256444-grw5s2pf	643	9	JHM	JHM	NNP
cord-256444-grw5s2pf	643	10	virus	virus	NN
cord-256444-grw5s2pf	643	11	infection	infection	NN
cord-256444-grw5s2pf	643	12	,	,	,
cord-256444-grw5s2pf	643	13	differentiated	differentiated	JJ
cord-256444-grw5s2pf	643	14	oligodendrocytes	oligodendrocyte	NNS
cord-256444-grw5s2pf	643	15	were	be	VBD
cord-256444-grw5s2pf	643	16	resistant	resistant	JJ
cord-256444-grw5s2pf	643	17	,	,	,
cord-256444-grw5s2pf	643	18	probably	probably	RB
cord-256444-grw5s2pf	643	19	due	due	IN
cord-256444-grw5s2pf	643	20	to	to	IN
cord-256444-grw5s2pf	643	21	a	a	DT
cord-256444-grw5s2pf	643	22	block	block	NN
cord-256444-grw5s2pf	643	23	in	in	IN
cord-256444-grw5s2pf	643	24	virion	virion	NN
cord-256444-grw5s2pf	643	25	uncoating	uncoating	NN
cord-256444-grw5s2pf	643	26	(	(	-LRB-
cord-256444-grw5s2pf	643	27	Beushausen	Beushausen	NNP
cord-256444-grw5s2pf	643	28	et	et	NNP
cord-256444-grw5s2pf	643	29	al	al	NNP
cord-256444-grw5s2pf	643	30	.	.	NNP
cord-256444-grw5s2pf	643	31	,	,	,
cord-256444-grw5s2pf	643	32	1987	1987	CD
cord-256444-grw5s2pf	643	33	)	)	-RRB-
cord-256444-grw5s2pf	643	34	.	.	.
cord-256444-grw5s2pf	644	1	The	the	DT
cord-256444-grw5s2pf	644	2	factors	factor	NNS
cord-256444-grw5s2pf	644	3	responsible	responsible	JJ
cord-256444-grw5s2pf	644	4	for	for	IN
cord-256444-grw5s2pf	644	5	the	the	DT
cord-256444-grw5s2pf	644	6	differences	difference	NNS
cord-256444-grw5s2pf	644	7	in	in	IN
cord-256444-grw5s2pf	644	8	these	these	DT
cord-256444-grw5s2pf	644	9	two	two	CD
cord-256444-grw5s2pf	644	10	types	type	NNS
cord-256444-grw5s2pf	644	11	of	of	IN
cord-256444-grw5s2pf	644	12	cells	cell	NNS
cord-256444-grw5s2pf	644	13	may	may	MD
cord-256444-grw5s2pf	644	14	involve	involve	VB
cord-256444-grw5s2pf	644	15	protein	protein	NN
cord-256444-grw5s2pf	644	16	kinases	kinase	NNS
cord-256444-grw5s2pf	644	17	(	(	-LRB-
cord-256444-grw5s2pf	644	18	Wilson	Wilson	NNP
cord-256444-grw5s2pf	644	19	et	et	NNP
cord-256444-grw5s2pf	644	20	al	al	NNP
cord-256444-grw5s2pf	644	21	.	.	NNP
cord-256444-grw5s2pf	644	22	,	,	,
cord-256444-grw5s2pf	644	23	1990	1990	CD
cord-256444-grw5s2pf	644	24	)	)	-RRB-
cord-256444-grw5s2pf	644	25	.	.	.
cord-256444-grw5s2pf	645	1	Additional	additional	JJ
cord-256444-grw5s2pf	645	2	cellular	cellular	JJ
cord-256444-grw5s2pf	645	3	factors	factor	NNS
cord-256444-grw5s2pf	645	4	may	may	MD
cord-256444-grw5s2pf	645	5	be	be	VB
cord-256444-grw5s2pf	645	6	required	require	VBN
cord-256444-grw5s2pf	645	7	for	for	IN
cord-256444-grw5s2pf	645	8	viral	viral	JJ
cord-256444-grw5s2pf	645	9	penetration	penetration	NN
cord-256444-grw5s2pf	645	10	and	and	CC
cord-256444-grw5s2pf	645	11	uncoating	uncoating	NN
cord-256444-grw5s2pf	645	12	.	.	.
cord-256444-grw5s2pf	646	1	Various	various	JJ
cord-256444-grw5s2pf	646	2	murine	murine	JJ
cord-256444-grw5s2pf	646	3	cell	cell	NN
cord-256444-grw5s2pf	646	4	lines	line	NNS
cord-256444-grw5s2pf	646	5	,	,	,
cord-256444-grw5s2pf	646	6	all	all	DT
cord-256444-grw5s2pf	646	7	of	of	IN
cord-256444-grw5s2pf	646	8	which	which	WDT
cord-256444-grw5s2pf	646	9	express	express	VBP
cord-256444-grw5s2pf	646	10	virus	virus	NN
cord-256444-grw5s2pf	646	11	receptors	receptor	NNS
cord-256444-grw5s2pf	646	12	,	,	,
cord-256444-grw5s2pf	646	13	show	show	VBP
cord-256444-grw5s2pf	646	14	different	different	JJ
cord-256444-grw5s2pf	646	15	degrees	degree	NNS
cord-256444-grw5s2pf	646	16	of	of	IN
cord-256444-grw5s2pf	646	17	susceptibility	susceptibility	NN
cord-256444-grw5s2pf	646	18	to	to	IN
cord-256444-grw5s2pf	646	19	infection	infection	NN
cord-256444-grw5s2pf	646	20	by	by	IN
cord-256444-grw5s2pf	646	21	different	different	JJ
cord-256444-grw5s2pf	646	22	MHV	MHV	NNP
cord-256444-grw5s2pf	646	23	strains	strain	NNS
cord-256444-grw5s2pf	646	24	(	(	-LRB-
cord-256444-grw5s2pf	646	25	Kooi	Kooi	NNP
cord-256444-grw5s2pf	646	26	et	et	NNP
cord-256444-grw5s2pf	646	27	al	al	NNP
cord-256444-grw5s2pf	646	28	.	.	NNP
cord-256444-grw5s2pf	646	29	,	,	,
cord-256444-grw5s2pf	646	30	1988	1988	CD
cord-256444-grw5s2pf	646	31	;	;	:
cord-256444-grw5s2pf	646	32	Asanaka	Asanaka	NNP
cord-256444-grw5s2pf	646	33	and	and	CC
cord-256444-grw5s2pf	646	34	Lai	Lai	NNP
cord-256444-grw5s2pf	646	35	,	,	,
cord-256444-grw5s2pf	646	36	1993	1993	CD
cord-256444-grw5s2pf	646	37	;	;	:
cord-256444-grw5s2pf	646	38	Yokomori	Yokomori	NNP
cord-256444-grw5s2pf	646	39	et	et	NNP
cord-256444-grw5s2pf	646	40	al	al	NNP
cord-256444-grw5s2pf	646	41	.	.	NNP
cord-256444-grw5s2pf	646	42	,	,	,
cord-256444-grw5s2pf	646	43	1993	1993	CD
cord-256444-grw5s2pf	646	44	)	)	-RRB-
cord-256444-grw5s2pf	646	45	.	.	.
cord-256444-grw5s2pf	647	1	Cell	cell	NN
cord-256444-grw5s2pf	647	2	-	-	HYPH
cord-256444-grw5s2pf	647	3	cell	cell	NN
cord-256444-grw5s2pf	647	4	and	and	CC
cord-256444-grw5s2pf	647	5	virus	virus	NN
cord-256444-grw5s2pf	647	6	-	-	HYPH
cord-256444-grw5s2pf	647	7	cell	cell	NN
cord-256444-grw5s2pf	647	8	fusion	fusion	NN
cord-256444-grw5s2pf	647	9	studies	study	NNS
cord-256444-grw5s2pf	647	10	indicated	indicate	VBD
cord-256444-grw5s2pf	647	11	that	that	IN
cord-256444-grw5s2pf	647	12	virus	virus	NN
cord-256444-grw5s2pf	647	13	infection	infection	NN
cord-256444-grw5s2pf	647	14	is	be	VBZ
cord-256444-grw5s2pf	647	15	blocked	block	VBN
cord-256444-grw5s2pf	647	16	at	at	IN
cord-256444-grw5s2pf	647	17	different	different	JJ
cord-256444-grw5s2pf	647	18	stages	stage	NNS
cord-256444-grw5s2pf	647	19	of	of	IN
cord-256444-grw5s2pf	647	20	virus	virus	NN
cord-256444-grw5s2pf	647	21	entry	entry	NN
cord-256444-grw5s2pf	647	22	,	,	,
cord-256444-grw5s2pf	647	23	including	include	VBG
cord-256444-grw5s2pf	647	24	penetration	penetration	NN
cord-256444-grw5s2pf	647	25	and	and	CC
cord-256444-grw5s2pf	647	26	uncoating	uncoating	NN
cord-256444-grw5s2pf	647	27	,	,	,
cord-256444-grw5s2pf	647	28	in	in	IN
cord-256444-grw5s2pf	647	29	different	different	JJ
cord-256444-grw5s2pf	647	30	cell	cell	NN
cord-256444-grw5s2pf	647	31	lines	line	NNS
cord-256444-grw5s2pf	647	32	(	(	-LRB-
cord-256444-grw5s2pf	647	33	van	van	NNP
cord-256444-grw5s2pf	647	34	Dinter	Dinter	NNP
cord-256444-grw5s2pf	647	35	and	and	CC
cord-256444-grw5s2pf	647	36	Flintoff	Flintoff	NNP
cord-256444-grw5s2pf	647	37	,	,	,
cord-256444-grw5s2pf	647	38	1987	1987	CD
cord-256444-grw5s2pf	647	39	;	;	:
cord-256444-grw5s2pf	647	40	Asanaka	Asanaka	NNP
cord-256444-grw5s2pf	647	41	and	and	CC
cord-256444-grw5s2pf	647	42	Lai	Lai	NNP
cord-256444-grw5s2pf	647	43	,	,	,
cord-256444-grw5s2pf	647	44	1993	1993	CD
cord-256444-grw5s2pf	647	45	)	)	-RRB-
cord-256444-grw5s2pf	647	46	.	.	.
cord-256444-grw5s2pf	648	1	These	these	DT
cord-256444-grw5s2pf	648	2	cell	cell	NN
cord-256444-grw5s2pf	648	3	lines	line	NNS
cord-256444-grw5s2pf	648	4	could	could	MD
cord-256444-grw5s2pf	648	5	be	be	VB
cord-256444-grw5s2pf	648	6	grouped	group	VBN
cord-256444-grw5s2pf	648	7	into	into	IN
cord-256444-grw5s2pf	648	8	at	at	RB
cord-256444-grw5s2pf	648	9	least	least	RBS
cord-256444-grw5s2pf	648	10	three	three	CD
cord-256444-grw5s2pf	648	11	complementation	complementation	NN
cord-256444-grw5s2pf	648	12	groups	group	NNS
cord-256444-grw5s2pf	648	13	with	with	IN
cord-256444-grw5s2pf	648	14	respect	respect	NN
cord-256444-grw5s2pf	648	15	to	to	IN
cord-256444-grw5s2pf	648	16	the	the	DT
cord-256444-grw5s2pf	648	17	virus	virus	NN
cord-256444-grw5s2pf	648	18	entry	entry	NN
cord-256444-grw5s2pf	648	19	process	process	NN
cord-256444-grw5s2pf	648	20	(	(	-LRB-
cord-256444-grw5s2pf	648	21	Flintoff	Flintoff	NNP
cord-256444-grw5s2pf	648	22	,	,	,
cord-256444-grw5s2pf	648	23	1984	1984	CD
cord-256444-grw5s2pf	648	24	;	;	.
cord-256444-grw5s2pf	649	1	Asanaka	Asanaka	NNP
cord-256444-grw5s2pf	649	2	and	and	CC
cord-256444-grw5s2pf	649	3	Lai	Lai	NNP
cord-256444-grw5s2pf	649	4	,	,	,
cord-256444-grw5s2pf	649	5	1993	1993	CD
cord-256444-grw5s2pf	649	6	)	)	-RRB-
cord-256444-grw5s2pf	649	7	.	.	.
cord-256444-grw5s2pf	650	1	Thus	thus	RB
cord-256444-grw5s2pf	650	2	,	,	,
cord-256444-grw5s2pf	650	3	virus	virus	NN
cord-256444-grw5s2pf	650	4	penetration	penetration	NN
cord-256444-grw5s2pf	650	5	and	and	CC
cord-256444-grw5s2pf	650	6	uncoating	uncoating	NN
cord-256444-grw5s2pf	650	7	appear	appear	VBP
cord-256444-grw5s2pf	650	8	to	to	TO
cord-256444-grw5s2pf	650	9	require	require	VB
cord-256444-grw5s2pf	650	10	separate	separate	JJ
cord-256444-grw5s2pf	650	11	cellular	cellular	JJ
cord-256444-grw5s2pf	650	12	factors	factor	NNS
cord-256444-grw5s2pf	650	13	.	.	.
cord-256444-grw5s2pf	651	1	It	-PRON-	PRP
cord-256444-grw5s2pf	651	2	has	have	VBZ
cord-256444-grw5s2pf	651	3	been	be	VBN
cord-256444-grw5s2pf	651	4	suggested	suggest	VBN
cord-256444-grw5s2pf	651	5	from	from	IN
cord-256444-grw5s2pf	651	6	the	the	DT
cord-256444-grw5s2pf	651	7	studies	study	NNS
cord-256444-grw5s2pf	651	8	using	use	VBG
cord-256444-grw5s2pf	651	9	recombinant	recombinant	JJ
cord-256444-grw5s2pf	651	10	viruses	virus	NNS
cord-256444-grw5s2pf	651	11	between	between	IN
cord-256444-grw5s2pf	651	12	the	the	DT
cord-256444-grw5s2pf	651	13	A69	A69	NNP
cord-256444-grw5s2pf	651	14	and	and	CC
cord-256444-grw5s2pf	651	15	JHM	JHM	NNP
cord-256444-grw5s2pf	651	16	strains	strain	NNS
cord-256444-grw5s2pf	651	17	of	of	IN
cord-256444-grw5s2pf	651	18	MHV	MHV	NNP
cord-256444-grw5s2pf	651	19	that	that	IN
cord-256444-grw5s2pf	651	20	viral	viral	JJ
cord-256444-grw5s2pf	651	21	S	s	NN
cord-256444-grw5s2pf	651	22	protein	protein	NN
cord-256444-grw5s2pf	651	23	may	may	MD
cord-256444-grw5s2pf	651	24	interact	interact	VB
cord-256444-grw5s2pf	651	25	with	with	IN
cord-256444-grw5s2pf	651	26	these	these	DT
cord-256444-grw5s2pf	651	27	cellular	cellular	JJ
cord-256444-grw5s2pf	651	28	factors	factor	NNS
cord-256444-grw5s2pf	651	29	.	.	.
cord-256444-grw5s2pf	652	1	The	the	DT
cord-256444-grw5s2pf	652	2	nature	nature	NN
cord-256444-grw5s2pf	652	3	of	of	IN
cord-256444-grw5s2pf	652	4	these	these	DT
cord-256444-grw5s2pf	652	5	factors	factor	NNS
cord-256444-grw5s2pf	652	6	is	be	VBZ
cord-256444-grw5s2pf	652	7	not	not	RB
cord-256444-grw5s2pf	652	8	yet	yet	RB
cord-256444-grw5s2pf	652	9	clear	clear	JJ
cord-256444-grw5s2pf	652	10	.	.	.
cord-256444-grw5s2pf	653	1	Following	follow	VBG
cord-256444-grw5s2pf	653	2	virus	virus	NN
cord-256444-grw5s2pf	653	3	uncoating	uncoating	NN
cord-256444-grw5s2pf	653	4	,	,	,
cord-256444-grw5s2pf	653	5	the	the	DT
cord-256444-grw5s2pf	653	6	first	first	JJ
cord-256444-grw5s2pf	653	7	macromolecular	macromolecular	JJ
cord-256444-grw5s2pf	653	8	synthetic	synthetic	JJ
cord-256444-grw5s2pf	653	9	event	event	NN
cord-256444-grw5s2pf	653	10	is	be	VBZ
cord-256444-grw5s2pf	653	11	predicted	predict	VBN
cord-256444-grw5s2pf	653	12	to	to	TO
cord-256444-grw5s2pf	653	13	be	be	VB
cord-256444-grw5s2pf	653	14	the	the	DT
cord-256444-grw5s2pf	653	15	synthesis	synthesis	NN
cord-256444-grw5s2pf	653	16	of	of	IN
cord-256444-grw5s2pf	653	17	an	an	DT
cord-256444-grw5s2pf	653	18	RNA	RNA	NNP
cord-256444-grw5s2pf	653	19	-	-	HYPH
cord-256444-grw5s2pf	653	20	dependent	dependent	JJ
cord-256444-grw5s2pf	653	21	RNA	RNA	NNP
cord-256444-grw5s2pf	653	22	polymerase(s	polymerase(s	NNP
cord-256444-grw5s2pf	653	23	)	)	-RRB-
cord-256444-grw5s2pf	653	24	from	from	IN
cord-256444-grw5s2pf	653	25	the	the	DT
cord-256444-grw5s2pf	653	26	incoming	incoming	JJ
cord-256444-grw5s2pf	653	27	viral	viral	JJ
cord-256444-grw5s2pf	653	28	genomic	genomic	JJ
cord-256444-grw5s2pf	653	29	RNA	RNA	NNP
cord-256444-grw5s2pf	653	30	,	,	,
cord-256444-grw5s2pf	653	31	as	as	IN
cord-256444-grw5s2pf	653	32	is	be	VBZ
cord-256444-grw5s2pf	653	33	the	the	DT
cord-256444-grw5s2pf	653	34	case	case	NN
cord-256444-grw5s2pf	653	35	for	for	IN
cord-256444-grw5s2pf	653	36	all	all	DT
cord-256444-grw5s2pf	653	37	positive	positive	JJ
cord-256444-grw5s2pf	653	38	-	-	HYPH
cord-256444-grw5s2pf	653	39	strand	strand	NN
cord-256444-grw5s2pf	653	40	RNA	RNA	NNP
cord-256444-grw5s2pf	653	41	viruses	virus	NNS
cord-256444-grw5s2pf	653	42	.	.	.
cord-256444-grw5s2pf	654	1	The	the	DT
cord-256444-grw5s2pf	654	2	polymerase	polymerase	NN
cord-256444-grw5s2pf	654	3	is	be	VBZ
cord-256444-grw5s2pf	654	4	translated	translate	VBN
cord-256444-grw5s2pf	654	5	from	from	IN
cord-256444-grw5s2pf	654	6	gene	gene	NN
cord-256444-grw5s2pf	654	7	1	1	CD
cord-256444-grw5s2pf	654	8	at	at	IN
cord-256444-grw5s2pf	654	9	the	the	DT
cord-256444-grw5s2pf	654	10	5	5	CD
cord-256444-grw5s2pf	654	11	'	'	NN
cord-256444-grw5s2pf	654	12	end	end	NN
cord-256444-grw5s2pf	654	13	of	of	IN
cord-256444-grw5s2pf	654	14	the	the	DT
cord-256444-grw5s2pf	654	15	genomic	genomic	JJ
cord-256444-grw5s2pf	654	16	RNA	RNA	NNP
cord-256444-grw5s2pf	654	17	,	,	,
cord-256444-grw5s2pf	654	18	most	most	RBS
cord-256444-grw5s2pf	654	19	likely	likely	JJ
cord-256444-grw5s2pf	654	20	directly	directly	RB
cord-256444-grw5s2pf	654	21	from	from	IN
cord-256444-grw5s2pf	654	22	the	the	DT
cord-256444-grw5s2pf	654	23	incoming	incoming	JJ
cord-256444-grw5s2pf	654	24	genomic	genomic	JJ
cord-256444-grw5s2pf	654	25	RNA	rna	NN
cord-256444-grw5s2pf	654	26	.	.	.
cord-256444-grw5s2pf	655	1	The	the	DT
cord-256444-grw5s2pf	655	2	process	process	NN
cord-256444-grw5s2pf	655	3	of	of	IN
cord-256444-grw5s2pf	655	4	primary	primary	JJ
cord-256444-grw5s2pf	655	5	translation	translation	NN
cord-256444-grw5s2pf	655	6	has	have	VBZ
cord-256444-grw5s2pf	655	7	not	not	RB
cord-256444-grw5s2pf	655	8	been	be	VBN
cord-256444-grw5s2pf	655	9	observed	observe	VBN
cord-256444-grw5s2pf	655	10	experimentally	experimentally	RB
cord-256444-grw5s2pf	655	11	.	.	.
cord-256444-grw5s2pf	656	1	However	however	RB
cord-256444-grw5s2pf	656	2	,	,	,
cord-256444-grw5s2pf	656	3	inhibitors	inhibitor	NNS
cord-256444-grw5s2pf	656	4	of	of	IN
cord-256444-grw5s2pf	656	5	protein	protein	NN
cord-256444-grw5s2pf	656	6	synthesis	synthesis	NN
cord-256444-grw5s2pf	656	7	applied	apply	VBD
cord-256444-grw5s2pf	656	8	early	early	RB
cord-256444-grw5s2pf	656	9	in	in	IN
cord-256444-grw5s2pf	656	10	the	the	DT
cord-256444-grw5s2pf	656	11	infection	infection	NN
cord-256444-grw5s2pf	656	12	blocked	block	VBD
cord-256444-grw5s2pf	656	13	RNA	RNA	NNP
cord-256444-grw5s2pf	656	14	transcription	transcription	NN
cord-256444-grw5s2pf	656	15	(	(	-LRB-
cord-256444-grw5s2pf	656	16	Mahy	Mahy	NNP
cord-256444-grw5s2pf	656	17	et	et	FW
cord-256444-grw5s2pf	656	18	al	al	NNP
cord-256444-grw5s2pf	656	19	.	.	NNP
cord-256444-grw5s2pf	656	20	,	,	,
cord-256444-grw5s2pf	656	21	1983	1983	CD
cord-256444-grw5s2pf	656	22	;	;	:
cord-256444-grw5s2pf	656	23	Perlman	Perlman	NNP
cord-256444-grw5s2pf	656	24	et	et	NNP
cord-256444-grw5s2pf	656	25	al	al	NNP
cord-256444-grw5s2pf	656	26	.	.	NNP
cord-256444-grw5s2pf	656	27	,	,	,
cord-256444-grw5s2pf	656	28	1986	1986	CD
cord-256444-grw5s2pf	656	29	;	;	:
cord-256444-grw5s2pf	656	30	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	656	31	and	and	CC
cord-256444-grw5s2pf	656	32	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	656	33	,	,	,
cord-256444-grw5s2pf	656	34	19861	19861	CD
cord-256444-grw5s2pf	656	35	,	,	,
cord-256444-grw5s2pf	656	36	indicating	indicate	VBG
cord-256444-grw5s2pf	656	37	that	that	IN
cord-256444-grw5s2pf	656	38	protein	protein	NN
cord-256444-grw5s2pf	656	39	synthesis	synthesis	NN
cord-256444-grw5s2pf	656	40	,	,	,
cord-256444-grw5s2pf	656	41	most	most	RBS
cord-256444-grw5s2pf	656	42	likely	likely	RB
cord-256444-grw5s2pf	656	43	the	the	DT
cord-256444-grw5s2pf	656	44	translation	translation	NN
cord-256444-grw5s2pf	656	45	of	of	IN
cord-256444-grw5s2pf	656	46	a	a	DT
cord-256444-grw5s2pf	656	47	viral	viral	JJ
cord-256444-grw5s2pf	656	48	polymerase	polymerase	NN
cord-256444-grw5s2pf	656	49	,	,	,
cord-256444-grw5s2pf	656	50	is	be	VBZ
cord-256444-grw5s2pf	656	51	necessary	necessary	JJ
cord-256444-grw5s2pf	656	52	for	for	IN
cord-256444-grw5s2pf	656	53	viral	viral	JJ
cord-256444-grw5s2pf	656	54	RNA	RNA	NNP
cord-256444-grw5s2pf	656	55	synthesis	synthesis	NN
cord-256444-grw5s2pf	656	56	.	.	.
cord-256444-grw5s2pf	657	1	This	this	DT
cord-256444-grw5s2pf	657	2	virus	virus	NN
cord-256444-grw5s2pf	657	3	-	-	HYPH
cord-256444-grw5s2pf	657	4	specific	specific	JJ
cord-256444-grw5s2pf	657	5	polymerase	polymerase	NN
cord-256444-grw5s2pf	657	6	is	be	VBZ
cord-256444-grw5s2pf	657	7	responsible	responsible	JJ
cord-256444-grw5s2pf	657	8	for	for	IN
cord-256444-grw5s2pf	657	9	the	the	DT
cord-256444-grw5s2pf	657	10	synthesis	synthesis	NN
cord-256444-grw5s2pf	657	11	of	of	IN
cord-256444-grw5s2pf	657	12	negative	negative	JJ
cord-256444-grw5s2pf	657	13	-	-	HYPH
cord-256444-grw5s2pf	657	14	strand	strand	NN
cord-256444-grw5s2pf	657	15	RNA	RNA	NNP
cord-256444-grw5s2pf	657	16	from	from	IN
cord-256444-grw5s2pf	657	17	the	the	DT
cord-256444-grw5s2pf	657	18	incoming	incoming	JJ
cord-256444-grw5s2pf	657	19	genomic	genomic	JJ
cord-256444-grw5s2pf	657	20	RNA	RNA	NNP
cord-256444-grw5s2pf	657	21	and	and	CC
cord-256444-grw5s2pf	657	22	subsequent	subsequent	JJ
cord-256444-grw5s2pf	657	23	transcription	transcription	NN
cord-256444-grw5s2pf	657	24	of	of	IN
cord-256444-grw5s2pf	657	25	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	657	26	from	from	IN
cord-256444-grw5s2pf	657	27	the	the	DT
cord-256444-grw5s2pf	657	28	negative	negative	JJ
cord-256444-grw5s2pf	657	29	-	-	HYPH
cord-256444-grw5s2pf	657	30	strand	strand	NN
cord-256444-grw5s2pf	657	31	template	template	NN
cord-256444-grw5s2pf	657	32	.	.	.
cord-256444-grw5s2pf	658	1	The	the	DT
cord-256444-grw5s2pf	658	2	nature	nature	NN
cord-256444-grw5s2pf	658	3	of	of	IN
cord-256444-grw5s2pf	658	4	polymerase	polymerase	NN
cord-256444-grw5s2pf	658	5	is	be	VBZ
cord-256444-grw5s2pf	658	6	discussed	discuss	VBN
cord-256444-grw5s2pf	658	7	in	in	IN
cord-256444-grw5s2pf	658	8	Section	Section	NNP
cord-256444-grw5s2pf	658	9	IV	IV	NNP
cord-256444-grw5s2pf	658	10	,	,	,
cord-256444-grw5s2pf	658	11	A.	a.	NN
cord-256444-grw5s2pf	659	1	Since	since	IN
cord-256444-grw5s2pf	659	2	the	the	DT
cord-256444-grw5s2pf	659	3	genomic	genomic	NN
cord-256444-grw5s2pf	659	4	-	-	HYPH
cord-256444-grw5s2pf	659	5	sized	sized	JJ
cord-256444-grw5s2pf	659	6	RNA	RNA	NNP
cord-256444-grw5s2pf	659	7	is	be	VBZ
cord-256444-grw5s2pf	659	8	used	use	VBN
cord-256444-grw5s2pf	659	9	for	for	IN
cord-256444-grw5s2pf	659	10	both	both	DT
cord-256444-grw5s2pf	659	11	packaging	packaging	NN
cord-256444-grw5s2pf	659	12	into	into	IN
cord-256444-grw5s2pf	659	13	virus	virus	NN
cord-256444-grw5s2pf	659	14	particles	particle	NNS
cord-256444-grw5s2pf	659	15	to	to	TO
cord-256444-grw5s2pf	659	16	become	become	VB
cord-256444-grw5s2pf	659	17	virion	virion	NN
cord-256444-grw5s2pf	659	18	RNA	RNA	NNP
cord-256444-grw5s2pf	659	19	and	and	CC
cord-256444-grw5s2pf	659	20	as	as	IN
cord-256444-grw5s2pf	659	21	an	an	DT
cord-256444-grw5s2pf	659	22	mRNA	mrna	NN
cord-256444-grw5s2pf	659	23	for	for	IN
cord-256444-grw5s2pf	659	24	protein	protein	NN
cord-256444-grw5s2pf	659	25	translation	translation	NN
cord-256444-grw5s2pf	659	26	,	,	,
cord-256444-grw5s2pf	659	27	the	the	DT
cord-256444-grw5s2pf	659	28	distinction	distinction	NN
cord-256444-grw5s2pf	659	29	between	between	IN
cord-256444-grw5s2pf	659	30	RNA	RNA	NNP
cord-256444-grw5s2pf	659	31	transcription	transcription	NN
cord-256444-grw5s2pf	659	32	and	and	CC
cord-256444-grw5s2pf	659	33	RNA	RNA	NNP
cord-256444-grw5s2pf	659	34	replication	replication	NN
cord-256444-grw5s2pf	659	35	is	be	VBZ
cord-256444-grw5s2pf	659	36	often	often	RB
cord-256444-grw5s2pf	659	37	blurred	blur	VBN
cord-256444-grw5s2pf	659	38	.	.	.
cord-256444-grw5s2pf	660	1	In	in	IN
cord-256444-grw5s2pf	660	2	this	this	DT
cord-256444-grw5s2pf	660	3	review	review	NN
cord-256444-grw5s2pf	660	4	,	,	,
cord-256444-grw5s2pf	660	5	we	-PRON-	PRP
cord-256444-grw5s2pf	660	6	will	will	MD
cord-256444-grw5s2pf	660	7	use	use	VB
cord-256444-grw5s2pf	660	8	the	the	DT
cord-256444-grw5s2pf	660	9	term	term	NN
cord-256444-grw5s2pf	660	10	"	"	``
cord-256444-grw5s2pf	660	11	transcription	transcription	NN
cord-256444-grw5s2pf	660	12	"	"	''
cord-256444-grw5s2pf	660	13	to	to	TO
cord-256444-grw5s2pf	660	14	describe	describe	VB
cord-256444-grw5s2pf	660	15	the	the	DT
cord-256444-grw5s2pf	660	16	synthesis	synthesis	NN
cord-256444-grw5s2pf	660	17	of	of	IN
cord-256444-grw5s2pf	660	18	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	660	19	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	660	20	as	as	RB
cord-256444-grw5s2pf	660	21	well	well	RB
cord-256444-grw5s2pf	660	22	as	as	IN
cord-256444-grw5s2pf	660	23	genomic	genomic	JJ
cord-256444-grw5s2pf	660	24	RNA	RNA	NNP
cord-256444-grw5s2pf	660	25	used	use	VBN
cord-256444-grw5s2pf	660	26	for	for	IN
cord-256444-grw5s2pf	660	27	translation	translation	NN
cord-256444-grw5s2pf	660	28	;	;	:
cord-256444-grw5s2pf	660	29	the	the	DT
cord-256444-grw5s2pf	660	30	term	term	NN
cord-256444-grw5s2pf	660	31	"	"	``
cord-256444-grw5s2pf	660	32	replication	replication	NN
cord-256444-grw5s2pf	660	33	"	"	''
cord-256444-grw5s2pf	660	34	will	will	MD
cord-256444-grw5s2pf	660	35	be	be	VB
cord-256444-grw5s2pf	660	36	used	use	VBN
cord-256444-grw5s2pf	660	37	to	to	TO
cord-256444-grw5s2pf	660	38	describe	describe	VB
cord-256444-grw5s2pf	660	39	the	the	DT
cord-256444-grw5s2pf	660	40	synthesis	synthesis	NN
cord-256444-grw5s2pf	660	41	of	of	IN
cord-256444-grw5s2pf	660	42	the	the	DT
cord-256444-grw5s2pf	660	43	genomic	genomic	JJ
cord-256444-grw5s2pf	660	44	RNA	rna	NN
cord-256444-grw5s2pf	660	45	destined	destine	VBN
cord-256444-grw5s2pf	660	46	to	to	TO
cord-256444-grw5s2pf	660	47	be	be	VB
cord-256444-grw5s2pf	660	48	packaged	package	VBN
cord-256444-grw5s2pf	660	49	into	into	IN
cord-256444-grw5s2pf	660	50	virions	virion	NNS
cord-256444-grw5s2pf	660	51	.	.	.
cord-256444-grw5s2pf	661	1	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	661	2	RNA	RNA	NNP
cord-256444-grw5s2pf	661	3	synthesis	synthesis	NN
cord-256444-grw5s2pf	661	4	occurs	occur	VBZ
cord-256444-grw5s2pf	661	5	via	via	IN
cord-256444-grw5s2pf	661	6	an	an	DT
cord-256444-grw5s2pf	661	7	RNA	RNA	NNP
cord-256444-grw5s2pf	661	8	-	-	HYPH
cord-256444-grw5s2pf	661	9	dependent	dependent	JJ
cord-256444-grw5s2pf	661	10	RNA	RNA	NNP
cord-256444-grw5s2pf	661	11	transcription	transcription	NN
cord-256444-grw5s2pf	661	12	process	process	NN
cord-256444-grw5s2pf	661	13	;	;	:
cord-256444-grw5s2pf	661	14	thus	thus	RB
cord-256444-grw5s2pf	661	15	,	,	,
cord-256444-grw5s2pf	661	16	RNA	RNA	NNP
cord-256444-grw5s2pf	661	17	synthesis	synthesis	NN
cord-256444-grw5s2pf	661	18	can	can	MD
cord-256444-grw5s2pf	661	19	occur	occur	VB
cord-256444-grw5s2pf	661	20	in	in	IN
cord-256444-grw5s2pf	661	21	the	the	DT
cord-256444-grw5s2pf	661	22	presence	presence	NN
cord-256444-grw5s2pf	661	23	of	of	IN
cord-256444-grw5s2pf	661	24	actinomycin	actinomycin	NNS
cord-256444-grw5s2pf	661	25	D	D	NNP
cord-256444-grw5s2pf	661	26	(	(	-LRB-
cord-256444-grw5s2pf	661	27	with	with	IN
cord-256444-grw5s2pf	661	28	the	the	DT
cord-256444-grw5s2pf	661	29	exception	exception	NN
cord-256444-grw5s2pf	661	30	of	of	IN
cord-256444-grw5s2pf	661	31	some	some	DT
cord-256444-grw5s2pf	661	32	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	661	33	,	,	,
cord-256444-grw5s2pf	661	34	as	as	IN
cord-256444-grw5s2pf	661	35	discussed	discuss	VBN
cord-256444-grw5s2pf	661	36	in	in	IN
cord-256444-grw5s2pf	661	37	Section	section	NN
cord-256444-grw5s2pf	661	38	V	v	NN
cord-256444-grw5s2pf	661	39	,	,	,
cord-256444-grw5s2pf	661	40	A	A	NNP
cord-256444-grw5s2pf	661	41	)	)	-RRB-
cord-256444-grw5s2pf	661	42	.	.	.
cord-256444-grw5s2pf	662	1	The	the	DT
cord-256444-grw5s2pf	662	2	majority	majority	NN
cord-256444-grw5s2pf	662	3	of	of	IN
cord-256444-grw5s2pf	662	4	the	the	DT
cord-256444-grw5s2pf	662	5	virus	virus	NN
cord-256444-grw5s2pf	662	6	-	-	HYPH
cord-256444-grw5s2pf	662	7	specific	specific	JJ
cord-256444-grw5s2pf	662	8	RNAs	rna	NNS
cord-256444-grw5s2pf	662	9	in	in	IN
cord-256444-grw5s2pf	662	10	the	the	DT
cord-256444-grw5s2pf	662	11	cells	cell	NNS
cord-256444-grw5s2pf	662	12	are	be	VBP
cord-256444-grw5s2pf	662	13	mRNAs	mrnas	CD
cord-256444-grw5s2pf	662	14	,	,	,
cord-256444-grw5s2pf	662	15	which	which	WDT
cord-256444-grw5s2pf	662	16	are	be	VBP
cord-256444-grw5s2pf	662	17	transcribed	transcribe	VBN
cord-256444-grw5s2pf	662	18	from	from	IN
cord-256444-grw5s2pf	662	19	a	a	DT
cord-256444-grw5s2pf	662	20	negative	negative	JJ
cord-256444-grw5s2pf	662	21	-	-	HYPH
cord-256444-grw5s2pf	662	22	strand	strand	NN
cord-256444-grw5s2pf	662	23	RNA	rna	NN
cord-256444-grw5s2pf	662	24	template	template	NN
cord-256444-grw5s2pf	662	25	.	.	.
cord-256444-grw5s2pf	663	1	For	for	IN
cord-256444-grw5s2pf	663	2	clarity	clarity	NN
cord-256444-grw5s2pf	663	3	of	of	IN
cord-256444-grw5s2pf	663	4	discussion	discussion	NN
cord-256444-grw5s2pf	663	5	,	,	,
cord-256444-grw5s2pf	663	6	the	the	DT
cord-256444-grw5s2pf	663	7	structure	structure	NN
cord-256444-grw5s2pf	663	8	of	of	IN
cord-256444-grw5s2pf	663	9	the	the	DT
cord-256444-grw5s2pf	663	10	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	663	11	will	will	MD
cord-256444-grw5s2pf	663	12	be	be	VB
cord-256444-grw5s2pf	663	13	discussed	discuss	VBN
cord-256444-grw5s2pf	663	14	first	first	RB
cord-256444-grw5s2pf	663	15	.	.	.
cord-256444-grw5s2pf	664	1	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	664	2	mRNAs	mrnas	PRP
cord-256444-grw5s2pf	664	3	consist	consist	VBP
cord-256444-grw5s2pf	664	4	of	of	IN
cord-256444-grw5s2pf	664	5	six	six	CD
cord-256444-grw5s2pf	664	6	to	to	TO
cord-256444-grw5s2pf	664	7	eight	eight	CD
cord-256444-grw5s2pf	664	8	species	specie	NNS
cord-256444-grw5s2pf	664	9	of	of	IN
cord-256444-grw5s2pf	664	10	different	different	JJ
cord-256444-grw5s2pf	664	11	sizes	size	NNS
cord-256444-grw5s2pf	664	12	,	,	,
cord-256444-grw5s2pf	664	13	depending	depend	VBG
cord-256444-grw5s2pf	664	14	on	on	IN
cord-256444-grw5s2pf	664	15	the	the	DT
cord-256444-grw5s2pf	664	16	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	664	17	species	specie	NNS
cord-256444-grw5s2pf	664	18	and	and	CC
cord-256444-grw5s2pf	664	19	strains	strain	NNS
cord-256444-grw5s2pf	664	20	(	(	-LRB-
cord-256444-grw5s2pf	664	21	Lai	Lai	NNP
cord-256444-grw5s2pf	664	22	,	,	,
cord-256444-grw5s2pf	664	23	1990	1990	CD
cord-256444-grw5s2pf	664	24	)	)	-RRB-
cord-256444-grw5s2pf	664	25	.	.	.
cord-256444-grw5s2pf	665	1	The	the	DT
cord-256444-grw5s2pf	665	2	largest	large	JJS
cord-256444-grw5s2pf	665	3	mRNA	mrna	NN
cord-256444-grw5s2pf	665	4	is	be	VBZ
cord-256444-grw5s2pf	665	5	equivalent	equivalent	JJ
cord-256444-grw5s2pf	665	6	to	to	IN
cord-256444-grw5s2pf	665	7	the	the	DT
cord-256444-grw5s2pf	665	8	genomic	genomic	JJ
cord-256444-grw5s2pf	665	9	RNA	RNA	NNP
cord-256444-grw5s2pf	665	10	,	,	,
cord-256444-grw5s2pf	665	11	and	and	CC
cord-256444-grw5s2pf	665	12	the	the	DT
cord-256444-grw5s2pf	665	13	remainder	remainder	NN
cord-256444-grw5s2pf	665	14	are	be	VBP
cord-256444-grw5s2pf	665	15	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	665	16	in	in	IN
cord-256444-grw5s2pf	665	17	size	size	NN
cord-256444-grw5s2pf	665	18	.	.	.
cord-256444-grw5s2pf	666	1	These	these	DT
cord-256444-grw5s2pf	666	2	RNAs	rna	NNS
cord-256444-grw5s2pf	666	3	are	be	VBP
cord-256444-grw5s2pf	666	4	designated	designate	VBN
cord-256444-grw5s2pf	666	5	mRNAs	mrnas	CD
cord-256444-grw5s2pf	666	6	1	1	CD
cord-256444-grw5s2pf	666	7	through	through	IN
cord-256444-grw5s2pf	666	8	7	7	CD
cord-256444-grw5s2pf	666	9	,	,	,
cord-256444-grw5s2pf	666	10	in	in	IN
cord-256444-grw5s2pf	666	11	order	order	NN
cord-256444-grw5s2pf	666	12	of	of	IN
cord-256444-grw5s2pf	666	13	decreasing	decrease	VBG
cord-256444-grw5s2pf	666	14	size	size	NN
cord-256444-grw5s2pf	666	15	,	,	,
cord-256444-grw5s2pf	666	16	according	accord	VBG
cord-256444-grw5s2pf	666	17	to	to	IN
cord-256444-grw5s2pf	666	18	the	the	DT
cord-256444-grw5s2pf	666	19	recommendations	recommendation	NNS
cord-256444-grw5s2pf	666	20	of	of	IN
cord-256444-grw5s2pf	666	21	the	the	DT
cord-256444-grw5s2pf	666	22	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	666	23	Study	Study	NNP
cord-256444-grw5s2pf	666	24	Group	Group	NNP
cord-256444-grw5s2pf	666	25	in	in	IN
cord-256444-grw5s2pf	666	26	1989	1989	CD
cord-256444-grw5s2pf	666	27	(	(	-LRB-
cord-256444-grw5s2pf	666	28	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	666	29	et	et	NNP
cord-256444-grw5s2pf	666	30	al	al	NNP
cord-256444-grw5s2pf	666	31	.	.	NNP
cord-256444-grw5s2pf	666	32	,	,	,
cord-256444-grw5s2pf	666	33	1990	1990	CD
cord-256444-grw5s2pf	666	34	)	)	-RRB-
cord-256444-grw5s2pf	666	35	.	.	.
cord-256444-grw5s2pf	667	1	Some	some	DT
cord-256444-grw5s2pf	667	2	mRNAs	mrnas	WDT
cord-256444-grw5s2pf	667	3	have	have	VBP
cord-256444-grw5s2pf	667	4	been	be	VBN
cord-256444-grw5s2pf	667	5	given	give	VBN
cord-256444-grw5s2pf	667	6	a	a	DT
cord-256444-grw5s2pf	667	7	hyphenated	hyphenated	JJ
cord-256444-grw5s2pf	667	8	name	name	NN
cord-256444-grw5s2pf	667	9	,	,	,
cord-256444-grw5s2pf	667	10	e.g.	e.g.	RB
cord-256444-grw5s2pf	667	11	,	,	,
cord-256444-grw5s2pf	667	12	mRNA	mRNA	NNP
cord-256444-grw5s2pf	667	13	2	2	CD
cord-256444-grw5s2pf	667	14	-	-	SYM
cord-256444-grw5s2pf	667	15	1	1	CD
cord-256444-grw5s2pf	667	16	,	,	,
cord-256444-grw5s2pf	667	17	because	because	IN
cord-256444-grw5s2pf	667	18	they	-PRON-	PRP
cord-256444-grw5s2pf	667	19	were	be	VBD
cord-256444-grw5s2pf	667	20	discovered	discover	VBN
cord-256444-grw5s2pf	667	21	after	after	IN
cord-256444-grw5s2pf	667	22	the	the	DT
cord-256444-grw5s2pf	667	23	original	original	JJ
cord-256444-grw5s2pf	667	24	set	set	NN
cord-256444-grw5s2pf	667	25	of	of	IN
cord-256444-grw5s2pf	667	26	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	667	27	was	be	VBD
cord-256444-grw5s2pf	667	28	named	name	VBN
cord-256444-grw5s2pf	667	29	.	.	.
cord-256444-grw5s2pf	668	1	They	-PRON-	PRP
cord-256444-grw5s2pf	668	2	have	have	VBP
cord-256444-grw5s2pf	668	3	a	a	DT
cord-256444-grw5s2pf	668	4	nested	nest	VBN
cord-256444-grw5s2pf	668	5	-	-	HYPH
cord-256444-grw5s2pf	668	6	set	set	VBN
cord-256444-grw5s2pf	668	7	structure	structure	NN
cord-256444-grw5s2pf	668	8	,	,	,
cord-256444-grw5s2pf	668	9	and	and	CC
cord-256444-grw5s2pf	668	10	all	all	DT
cord-256444-grw5s2pf	668	11	of	of	IN
cord-256444-grw5s2pf	668	12	them	-PRON-	PRP
cord-256444-grw5s2pf	668	13	contain	contain	VBP
cord-256444-grw5s2pf	668	14	sequences	sequence	NNS
cord-256444-grw5s2pf	668	15	starting	start	VBG
cord-256444-grw5s2pf	668	16	at	at	IN
cord-256444-grw5s2pf	668	17	the	the	DT
cord-256444-grw5s2pf	668	18	3	3	CD
cord-256444-grw5s2pf	668	19	'	'	NN
cord-256444-grw5s2pf	668	20	terminus	terminus	NN
cord-256444-grw5s2pf	668	21	and	and	CC
cord-256444-grw5s2pf	668	22	extending	extend	VBG
cord-256444-grw5s2pf	668	23	to	to	IN
cord-256444-grw5s2pf	668	24	various	various	JJ
cord-256444-grw5s2pf	668	25	distances	distance	NNS
cord-256444-grw5s2pf	668	26	toward	toward	IN
cord-256444-grw5s2pf	668	27	the	the	DT
cord-256444-grw5s2pf	668	28	5	5	CD
cord-256444-grw5s2pf	668	29	'	'	NN
cord-256444-grw5s2pf	668	30	end	end	NN
cord-256444-grw5s2pf	669	1	(	(	-LRB-
cord-256444-grw5s2pf	669	2	Stern	Stern	NNP
cord-256444-grw5s2pf	669	3	and	and	CC
cord-256444-grw5s2pf	669	4	Kennedy	Kennedy	NNP
cord-256444-grw5s2pf	669	5	,	,	,
cord-256444-grw5s2pf	669	6	1980b	1980b	CD
cord-256444-grw5s2pf	669	7	;	;	:
cord-256444-grw5s2pf	669	8	Lai	Lai	NNP
cord-256444-grw5s2pf	669	9	et	et	FW
cord-256444-grw5s2pf	669	10	al	al	NNP
cord-256444-grw5s2pf	669	11	.	.	NNP
cord-256444-grw5s2pf	669	12	,	,	,
cord-256444-grw5s2pf	669	13	1981	1981	CD
cord-256444-grw5s2pf	669	14	;	;	:
cord-256444-grw5s2pf	669	15	Leibowitz	Leibowitz	NNP
cord-256444-grw5s2pf	669	16	et	et	NNP
cord-256444-grw5s2pf	669	17	al	al	NNP
cord-256444-grw5s2pf	669	18	.	.	NNP
cord-256444-grw5s2pf	669	19	,	,	,
cord-256444-grw5s2pf	669	20	1981	1981	CD
cord-256444-grw5s2pf	669	21	)	)	-RRB-
cord-256444-grw5s2pf	669	22	.	.	.
cord-256444-grw5s2pf	670	1	The	the	DT
cord-256444-grw5s2pf	670	2	smallest	small	JJS
cord-256444-grw5s2pf	670	3	mRNA	mrna	NN
cord-256444-grw5s2pf	670	4	contains	contain	VBZ
cord-256444-grw5s2pf	670	5	only	only	RB
cord-256444-grw5s2pf	670	6	the	the	DT
cord-256444-grw5s2pf	670	7	3	3	CD
cord-256444-grw5s2pf	670	8	'	'	''
cord-256444-grw5s2pf	670	9	terminal	terminal	JJ
cord-256444-grw5s2pf	670	10	ORF	ORF	NNP
cord-256444-grw5s2pf	670	11	,	,	,
cord-256444-grw5s2pf	670	12	while	while	IN
cord-256444-grw5s2pf	670	13	each	each	DT
cord-256444-grw5s2pf	670	14	next	next	JJ
cord-256444-grw5s2pf	670	15	larger	large	JJR
cord-256444-grw5s2pf	670	16	mRNA	mrna	NN
cord-256444-grw5s2pf	670	17	contains	contain	VBZ
cord-256444-grw5s2pf	670	18	one	one	CD
cord-256444-grw5s2pf	670	19	additional	additional	JJ
cord-256444-grw5s2pf	670	20	ORF	orf	NN
cord-256444-grw5s2pf	670	21	.	.	.
cord-256444-grw5s2pf	671	1	The	the	DT
cord-256444-grw5s2pf	671	2	structure	structure	NN
cord-256444-grw5s2pf	671	3	of	of	IN
cord-256444-grw5s2pf	671	4	the	the	DT
cord-256444-grw5s2pf	671	5	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	671	6	in	in	IN
cord-256444-grw5s2pf	671	7	relation	relation	NN
cord-256444-grw5s2pf	671	8	to	to	IN
cord-256444-grw5s2pf	671	9	the	the	DT
cord-256444-grw5s2pf	671	10	genome	genome	NN
cord-256444-grw5s2pf	671	11	structure	structure	NN
cord-256444-grw5s2pf	671	12	is	be	VBZ
cord-256444-grw5s2pf	671	13	shown	show	VBN
cord-256444-grw5s2pf	671	14	in	in	IN
cord-256444-grw5s2pf	671	15	Fig	Fig	NNP
cord-256444-grw5s2pf	671	16	.	.	.
cord-256444-grw5s2pf	672	1	7	7	CD
cord-256444-grw5s2pf	672	2	.	.	.
cord-256444-grw5s2pf	673	1	Thus	thus	RB
cord-256444-grw5s2pf	673	2	,	,	,
cord-256444-grw5s2pf	673	3	except	except	IN
cord-256444-grw5s2pf	673	4	for	for	IN
cord-256444-grw5s2pf	673	5	the	the	DT
cord-256444-grw5s2pf	673	6	smallest	small	JJS
cord-256444-grw5s2pf	673	7	mRNA	mrna	NN
cord-256444-grw5s2pf	673	8	,	,	,
cord-256444-grw5s2pf	673	9	all	all	DT
cord-256444-grw5s2pf	673	10	of	of	IN
cord-256444-grw5s2pf	673	11	the	the	DT
cord-256444-grw5s2pf	673	12	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	673	13	are	be	VBP
cord-256444-grw5s2pf	673	14	structurally	structurally	RB
cord-256444-grw5s2pf	673	15	poly-	poly-	JJ
cord-256444-grw5s2pf	673	16	cistronic	cistronic	NNP
cord-256444-grw5s2pf	673	17	.	.	.
cord-256444-grw5s2pf	674	1	In	in	IN
cord-256444-grw5s2pf	674	2	general	general	JJ
cord-256444-grw5s2pf	674	3	,	,	,
cord-256444-grw5s2pf	674	4	each	each	DT
cord-256444-grw5s2pf	674	5	ORF	ORF	NNP
cord-256444-grw5s2pf	674	6	in	in	IN
cord-256444-grw5s2pf	674	7	the	the	DT
cord-256444-grw5s2pf	674	8	genome	genome	NN
cord-256444-grw5s2pf	674	9	is	be	VBZ
cord-256444-grw5s2pf	674	10	represented	represent	VBN
cord-256444-grw5s2pf	674	11	by	by	IN
cord-256444-grw5s2pf	674	12	an	an	DT
cord-256444-grw5s2pf	674	13	mRNA	mrna	NN
cord-256444-grw5s2pf	674	14	,	,	,
cord-256444-grw5s2pf	674	15	whose	whose	WP$
cord-256444-grw5s2pf	674	16	sequence	sequence	NN
cord-256444-grw5s2pf	674	17	starts	start	VBZ
cord-256444-grw5s2pf	674	18	from	from	IN
cord-256444-grw5s2pf	674	19	a	a	DT
cord-256444-grw5s2pf	674	20	consensus	consensus	NN
cord-256444-grw5s2pf	674	21	signal	signal	NN
cord-256444-grw5s2pf	674	22	upstream	upstream	RB
cord-256444-grw5s2pf	674	23	of	of	IN
cord-256444-grw5s2pf	674	24	the	the	DT
cord-256444-grw5s2pf	674	25	ORF	ORF	NNP
cord-256444-grw5s2pf	674	26	,	,	,
cord-256444-grw5s2pf	674	27	and	and	CC
cord-256444-grw5s2pf	674	28	only	only	RB
cord-256444-grw5s2pf	674	29	the	the	DT
cord-256444-grw5s2pf	674	30	5	5	CD
cord-256444-grw5s2pf	674	31	'	'	''
cord-256444-grw5s2pf	674	32	most	most	JJS
cord-256444-grw5s2pf	674	33	ORF	ORF	NNP
cord-256444-grw5s2pf	674	34	of	of	IN
cord-256444-grw5s2pf	674	35	each	each	DT
cord-256444-grw5s2pf	674	36	mRNA	mrna	NN
cord-256444-grw5s2pf	674	37	can	can	MD
cord-256444-grw5s2pf	674	38	be	be	VB
cord-256444-grw5s2pf	674	39	translated	translate	VBN
cord-256444-grw5s2pf	674	40	;	;	:
cord-256444-grw5s2pf	674	41	thus	thus	RB
cord-256444-grw5s2pf	674	42	,	,	,
cord-256444-grw5s2pf	674	43	each	each	DT
cord-256444-grw5s2pf	674	44	mRNA	mrna	NN
cord-256444-grw5s2pf	674	45	is	be	VBZ
cord-256444-grw5s2pf	674	46	functionally	functionally	RB
cord-256444-grw5s2pf	674	47	monocistronic	monocistronic	JJ
cord-256444-grw5s2pf	674	48	.	.	.
cord-256444-grw5s2pf	675	1	However	however	RB
cord-256444-grw5s2pf	675	2	,	,	,
cord-256444-grw5s2pf	675	3	there	there	EX
cord-256444-grw5s2pf	675	4	are	be	VBP
cord-256444-grw5s2pf	675	5	exceptions	exception	NNS
cord-256444-grw5s2pf	675	6	:	:	:
cord-256444-grw5s2pf	675	7	some	some	DT
cord-256444-grw5s2pf	675	8	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	675	9	,	,	,
cord-256444-grw5s2pf	675	10	e.g.	e.g.	RB
cord-256444-grw5s2pf	675	11	,	,	,
cord-256444-grw5s2pf	675	12	mRNA	mrna	NN
cord-256444-grw5s2pf	675	13	5	5	CD
cord-256444-grw5s2pf	675	14	of	of	IN
cord-256444-grw5s2pf	675	15	MHV	MHV	NNP
cord-256444-grw5s2pf	675	16	and	and	CC
cord-256444-grw5s2pf	675	17	mRNA	mrna	NN
cord-256444-grw5s2pf	676	1	3	3	CD
cord-256444-grw5s2pf	676	2	of	of	IN
cord-256444-grw5s2pf	676	3	IBV	IBV	NNP
cord-256444-grw5s2pf	676	4	,	,	,
cord-256444-grw5s2pf	676	5	are	be	VBP
cord-256444-grw5s2pf	676	6	translated	translate	VBN
cord-256444-grw5s2pf	676	7	into	into	IN
cord-256444-grw5s2pf	676	8	two	two	CD
cord-256444-grw5s2pf	676	9	or	or	CC
cord-256444-grw5s2pf	676	10	three	three	CD
cord-256444-grw5s2pf	676	11	proteins	protein	NNS
cord-256444-grw5s2pf	676	12	by	by	IN
cord-256444-grw5s2pf	676	13	different	different	JJ
cord-256444-grw5s2pf	676	14	mechanisms	mechanism	NNS
cord-256444-grw5s2pf	676	15	(	(	-LRB-
cord-256444-grw5s2pf	676	16	see	see	VB
cord-256444-grw5s2pf	676	17	Section	section	NN
cord-256444-grw5s2pf	676	18	V	v	NN
cord-256444-grw5s2pf	676	19	,	,	,
cord-256444-grw5s2pf	676	20	G	G	NNP
cord-256444-grw5s2pf	676	21	)	)	-RRB-
cord-256444-grw5s2pf	676	22	.	.	.
cord-256444-grw5s2pf	677	1	Several	several	JJ
cord-256444-grw5s2pf	677	2	additional	additional	JJ
cord-256444-grw5s2pf	677	3	minor	minor	JJ
cord-256444-grw5s2pf	677	4	mRNA	mrna	NN
cord-256444-grw5s2pf	677	5	species	specie	NNS
cord-256444-grw5s2pf	677	6	have	have	VBP
cord-256444-grw5s2pf	677	7	been	be	VBN
cord-256444-grw5s2pf	677	8	detected	detect	VBN
cord-256444-grw5s2pf	677	9	,	,	,
cord-256444-grw5s2pf	677	10	some	some	DT
cord-256444-grw5s2pf	677	11	of	of	IN
cord-256444-grw5s2pf	677	12	which	which	WDT
cord-256444-grw5s2pf	677	13	could	could	MD
cord-256444-grw5s2pf	677	14	only	only	RB
cord-256444-grw5s2pf	677	15	be	be	VB
cord-256444-grw5s2pf	677	16	detected	detect	VBN
cord-256444-grw5s2pf	677	17	by	by	IN
cord-256444-grw5s2pf	677	18	reverse	reverse	JJ
cord-256444-grw5s2pf	677	19	transcription	transcription	NN
cord-256444-grw5s2pf	677	20	-	-	HYPH
cord-256444-grw5s2pf	677	21	polymerase	polymerase	NN
cord-256444-grw5s2pf	677	22	chain	chain	NN
cord-256444-grw5s2pf	677	23	reaction	reaction	NN
cord-256444-grw5s2pf	677	24	(	(	-LRB-
cord-256444-grw5s2pf	677	25	La	La	NNP
cord-256444-grw5s2pf	677	26	Monica	Monica	NNP
cord-256444-grw5s2pf	677	27	et	et	NNP
cord-256444-grw5s2pf	677	28	al	al	NNP
cord-256444-grw5s2pf	677	29	.	.	NNP
cord-256444-grw5s2pf	677	30	,	,	,
cord-256444-grw5s2pf	677	31	1992	1992	CD
cord-256444-grw5s2pf	677	32	;	;	.
cord-256444-grw5s2pf	678	1	Schaad	Schaad	NNP
cord-256444-grw5s2pf	678	2	and	and	CC
cord-256444-grw5s2pf	678	3	Baric	Baric	NNP
cord-256444-grw5s2pf	678	4	,	,	,
cord-256444-grw5s2pf	678	5	1993	1993	CD
cord-256444-grw5s2pf	678	6	)	)	-RRB-
cord-256444-grw5s2pf	678	7	.	.	.
cord-256444-grw5s2pf	679	1	These	these	DT
cord-256444-grw5s2pf	679	2	minor	minor	JJ
cord-256444-grw5s2pf	679	3	RNAs	rna	NNS
cord-256444-grw5s2pf	679	4	probably	probably	RB
cord-256444-grw5s2pf	679	5	represent	represent	VBP
cord-256444-grw5s2pf	679	6	RNA	RNA	NNP
cord-256444-grw5s2pf	679	7	transcripts	transcript	NNS
cord-256444-grw5s2pf	679	8	from	from	IN
cord-256444-grw5s2pf	679	9	weak	weak	JJ
cord-256444-grw5s2pf	679	10	or	or	CC
cord-256444-grw5s2pf	679	11	atypical	atypical	JJ
cord-256444-grw5s2pf	679	12	mRNA	mrna	NN
cord-256444-grw5s2pf	679	13	start	start	NN
cord-256444-grw5s2pf	679	14	signals	signal	NNS
cord-256444-grw5s2pf	679	15	(	(	-LRB-
cord-256444-grw5s2pf	679	16	see	see	VB
cord-256444-grw5s2pf	679	17	below	below	RB
cord-256444-grw5s2pf	679	18	)	)	-RRB-
cord-256444-grw5s2pf	679	19	.	.	.
cord-256444-grw5s2pf	680	1	Most	Most	JJS
cord-256444-grw5s2pf	680	2	do	do	VBP
cord-256444-grw5s2pf	680	3	not	not	RB
cord-256444-grw5s2pf	680	4	contain	contain	VB
cord-256444-grw5s2pf	680	5	a	a	DT
cord-256444-grw5s2pf	680	6	complete	complete	JJ
cord-256444-grw5s2pf	680	7	ORF	orf	NN
cord-256444-grw5s2pf	680	8	at	at	IN
cord-256444-grw5s2pf	680	9	the	the	DT
cord-256444-grw5s2pf	680	10	5	5	CD
cord-256444-grw5s2pf	680	11	'	'	NN
cord-256444-grw5s2pf	680	12	end	end	NN
cord-256444-grw5s2pf	680	13	;	;	:
cord-256444-grw5s2pf	680	14	thus	thus	RB
cord-256444-grw5s2pf	680	15	,	,	,
cord-256444-grw5s2pf	680	16	they	-PRON-	PRP
cord-256444-grw5s2pf	680	17	are	be	VBP
cord-256444-grw5s2pf	680	18	probably	probably	RB
cord-256444-grw5s2pf	680	19	not	not	RB
cord-256444-grw5s2pf	680	20	functional	functional	JJ
cord-256444-grw5s2pf	680	21	.	.	.
cord-256444-grw5s2pf	681	1	Furthermore	furthermore	RB
cord-256444-grw5s2pf	681	2	,	,	,
cord-256444-grw5s2pf	681	3	in	in	IN
cord-256444-grw5s2pf	681	4	MHV	MHV	NNP
cord-256444-grw5s2pf	681	5	,	,	,
cord-256444-grw5s2pf	681	6	several	several	JJ
cord-256444-grw5s2pf	681	7	mRNAs	mrna	NNS
cord-256444-grw5s2pf	681	8	,	,	,
cord-256444-grw5s2pf	681	9	e.g.	e.g.	RB
cord-256444-grw5s2pf	681	10	,	,	,
cord-256444-grw5s2pf	681	11	mRNAs	mrnas	CD
cord-256444-grw5s2pf	681	12	2	2	CD
cord-256444-grw5s2pf	681	13	-	-	SYM
cord-256444-grw5s2pf	681	14	1	1	CD
cord-256444-grw5s2pf	681	15	,	,	,
cord-256444-grw5s2pf	681	16	2	2	CD
cord-256444-grw5s2pf	681	17	-	-	SYM
cord-256444-grw5s2pf	681	18	2	2	CD
cord-256444-grw5s2pf	681	19	,	,	,
cord-256444-grw5s2pf	681	20	and	and	CC
cord-256444-grw5s2pf	681	21	3	3	CD
cord-256444-grw5s2pf	681	22	-	-	SYM
cord-256444-grw5s2pf	681	23	1	1	CD
cord-256444-grw5s2pf	681	24	,	,	,
cord-256444-grw5s2pf	681	25	are	be	VBP
cord-256444-grw5s2pf	681	26	transcribed	transcribe	VBN
cord-256444-grw5s2pf	681	27	only	only	RB
cord-256444-grw5s2pf	681	28	in	in	IN
cord-256444-grw5s2pf	681	29	some	some	DT
cord-256444-grw5s2pf	681	30	virus	virus	NN
cord-256444-grw5s2pf	681	31	strains	strain	VBZ
cord-256444-grw5s2pf	681	32	La	La	NNP
cord-256444-grw5s2pf	681	33	Monica	Monica	NNP
cord-256444-grw5s2pf	681	34	et	et	NNP
cord-256444-grw5s2pf	681	35	al	al	NNP
cord-256444-grw5s2pf	681	36	.	.	NNP
cord-256444-grw5s2pf	681	37	,	,	,
cord-256444-grw5s2pf	681	38	1992	1992	CD
cord-256444-grw5s2pf	681	39	)	)	-RRB-
cord-256444-grw5s2pf	681	40	.	.	.
cord-256444-grw5s2pf	682	1	The	the	DT
cord-256444-grw5s2pf	682	2	syntheses	synthesis	NNS
cord-256444-grw5s2pf	682	3	of	of	IN
cord-256444-grw5s2pf	682	4	these	these	DT
cord-256444-grw5s2pf	682	5	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	682	6	appear	appear	VBP
cord-256444-grw5s2pf	682	7	to	to	TO
cord-256444-grw5s2pf	682	8	be	be	VB
cord-256444-grw5s2pf	682	9	differentially	differentially	RB
cord-256444-grw5s2pf	682	10	regulated	regulate	VBN
cord-256444-grw5s2pf	682	11	by	by	IN
cord-256444-grw5s2pf	682	12	the	the	DT
cord-256444-grw5s2pf	682	13	sequence	sequence	NN
cord-256444-grw5s2pf	682	14	at	at	IN
cord-256444-grw5s2pf	682	15	the	the	DT
cord-256444-grw5s2pf	682	16	5	5	CD
cord-256444-grw5s2pf	682	17	'	'	NN
cord-256444-grw5s2pf	682	18	end	end	NN
cord-256444-grw5s2pf	682	19	of	of	IN
cord-256444-grw5s2pf	682	20	the	the	DT
cord-256444-grw5s2pf	682	21	viral	viral	JJ
cord-256444-grw5s2pf	682	22	genome	genome	NN
cord-256444-grw5s2pf	682	23	La	La	NNP
cord-256444-grw5s2pf	682	24	Monica	Monica	NNP
cord-256444-grw5s2pf	682	25	et	et	NNP
cord-256444-grw5s2pf	682	26	al	al	NNP
cord-256444-grw5s2pf	682	27	.	.	NNP
cord-256444-grw5s2pf	682	28	,	,	,
cord-256444-grw5s2pf	682	29	1992	1992	CD
cord-256444-grw5s2pf	682	30	)	)	-RRB-
cord-256444-grw5s2pf	682	31	.	.	.
cord-256444-grw5s2pf	683	1	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	683	2	mRNAs	mrnas	WDT
cord-256444-grw5s2pf	683	3	have	have	VBP
cord-256444-grw5s2pf	683	4	another	another	DT
cord-256444-grw5s2pf	683	5	unique	unique	JJ
cord-256444-grw5s2pf	683	6	structural	structural	JJ
cord-256444-grw5s2pf	683	7	feature	feature	NN
cord-256444-grw5s2pf	683	8	:	:	:
cord-256444-grw5s2pf	683	9	their	-PRON-	PRP$
cord-256444-grw5s2pf	683	10	5	5	CD
cord-256444-grw5s2pf	683	11	'	'	''
cord-256444-grw5s2pf	683	12	ends	end	NNS
cord-256444-grw5s2pf	683	13	have	have	VBP
cord-256444-grw5s2pf	683	14	a	a	DT
cord-256444-grw5s2pf	683	15	leader	leader	NN
cord-256444-grw5s2pf	683	16	sequence	sequence	NN
cord-256444-grw5s2pf	683	17	of	of	IN
cord-256444-grw5s2pf	683	18	approximately	approximately	RB
cord-256444-grw5s2pf	683	19	60	60	CD
cord-256444-grw5s2pf	683	20	-	-	SYM
cord-256444-grw5s2pf	683	21	90	90	CD
cord-256444-grw5s2pf	683	22	nucleotides	nucleotide	NNS
cord-256444-grw5s2pf	683	23	,	,	,
cord-256444-grw5s2pf	683	24	which	which	WDT
cord-256444-grw5s2pf	683	25	is	be	VBZ
cord-256444-grw5s2pf	683	26	derived	derive	VBN
cord-256444-grw5s2pf	683	27	from	from	IN
cord-256444-grw5s2pf	683	28	the	the	DT
cord-256444-grw5s2pf	683	29	5	5	CD
cord-256444-grw5s2pf	683	30	'	'	NN
cord-256444-grw5s2pf	683	31	end	end	NN
cord-256444-grw5s2pf	683	32	of	of	IN
cord-256444-grw5s2pf	683	33	the	the	DT
cord-256444-grw5s2pf	683	34	genomic	genomic	JJ
cord-256444-grw5s2pf	683	35	RNA	RNA	NNP
cord-256444-grw5s2pf	683	36	(	(	-LRB-
cord-256444-grw5s2pf	683	37	Lai	Lai	NNP
cord-256444-grw5s2pf	683	38	et	et	FW
cord-256444-grw5s2pf	683	39	al	al	NNP
cord-256444-grw5s2pf	683	40	.	.	NNP
cord-256444-grw5s2pf	683	41	,	,	,
cord-256444-grw5s2pf	683	42	,	,	,
cord-256444-grw5s2pf	683	43	1983	1983	CD
cord-256444-grw5s2pf	683	44	Spaan	Spaan	NNP
cord-256444-grw5s2pf	683	45	et	et	FW
cord-256444-grw5s2pf	683	46	al	al	NNP
cord-256444-grw5s2pf	683	47	.	.	NNP
cord-256444-grw5s2pf	683	48	,	,	,
cord-256444-grw5s2pf	683	49	1983	1983	CD
cord-256444-grw5s2pf	683	50	)	)	-RRB-
cord-256444-grw5s2pf	683	51	.	.	.
cord-256444-grw5s2pf	684	1	The	the	DT
cord-256444-grw5s2pf	684	2	leader	leader	NN
cord-256444-grw5s2pf	684	3	sequences	sequence	NNS
cord-256444-grw5s2pf	684	4	of	of	IN
cord-256444-grw5s2pf	684	5	all	all	PDT
cord-256444-grw5s2pf	684	6	the	the	DT
cord-256444-grw5s2pf	684	7	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	684	8	are	be	VBP
cord-256444-grw5s2pf	684	9	identical	identical	JJ
cord-256444-grw5s2pf	684	10	for	for	IN
cord-256444-grw5s2pf	684	11	a	a	DT
cord-256444-grw5s2pf	684	12	given	give	VBN
cord-256444-grw5s2pf	684	13	strain	strain	NN
cord-256444-grw5s2pf	684	14	of	of	IN
cord-256444-grw5s2pf	684	15	virus	virus	NN
cord-256444-grw5s2pf	684	16	,	,	,
cord-256444-grw5s2pf	684	17	except	except	IN
cord-256444-grw5s2pf	684	18	for	for	IN
cord-256444-grw5s2pf	684	19	slight	slight	JJ
cord-256444-grw5s2pf	684	20	variations	variation	NNS
cord-256444-grw5s2pf	684	21	at	at	IN
cord-256444-grw5s2pf	684	22	some	some	DT
cord-256444-grw5s2pf	684	23	of	of	IN
cord-256444-grw5s2pf	684	24	the	the	DT
cord-256444-grw5s2pf	684	25	leader	leader	NN
cord-256444-grw5s2pf	684	26	-	-	HYPH
cord-256444-grw5s2pf	684	27	mRNA	mrna	NN
cord-256444-grw5s2pf	684	28	fusion	fusion	NN
cord-256444-grw5s2pf	684	29	sites	site	NNS
cord-256444-grw5s2pf	684	30	,	,	,
cord-256444-grw5s2pf	684	31	and	and	CC
cord-256444-grw5s2pf	684	32	are	be	VBP
cord-256444-grw5s2pf	684	33	identical	identical	JJ
cord-256444-grw5s2pf	684	34	to	to	IN
cord-256444-grw5s2pf	684	35	the	the	DT
cord-256444-grw5s2pf	684	36	sequence	sequence	NN
cord-256444-grw5s2pf	684	37	present	present	JJ
cord-256444-grw5s2pf	684	38	at	at	IN
cord-256444-grw5s2pf	684	39	the	the	DT
cord-256444-grw5s2pf	684	40	5	5	CD
cord-256444-grw5s2pf	684	41	'	'	NN
cord-256444-grw5s2pf	684	42	end	end	NN
cord-256444-grw5s2pf	684	43	of	of	IN
cord-256444-grw5s2pf	684	44	the	the	DT
cord-256444-grw5s2pf	684	45	genomic	genomic	JJ
cord-256444-grw5s2pf	684	46	RNA	rna	NN
cord-256444-grw5s2pf	684	47	.	.	.
cord-256444-grw5s2pf	685	1	At	at	IN
cord-256444-grw5s2pf	685	2	the	the	DT
cord-256444-grw5s2pf	685	3	mRNA	mRNA	NNP
cord-256444-grw5s2pf	685	4	start	start	VB
cord-256444-grw5s2pf	685	5	sites	site	NNS
cord-256444-grw5s2pf	685	6	on	on	IN
cord-256444-grw5s2pf	685	7	the	the	DT
cord-256444-grw5s2pf	685	8	viral	viral	JJ
cord-256444-grw5s2pf	685	9	genomic	genomic	JJ
cord-256444-grw5s2pf	685	10	RNA	RNA	NNP
cord-256444-grw5s2pf	685	11	,	,	,
cord-256444-grw5s2pf	685	12	there	there	EX
cord-256444-grw5s2pf	685	13	is	be	VBZ
cord-256444-grw5s2pf	685	14	a	a	DT
cord-256444-grw5s2pf	685	15	short	short	JJ
cord-256444-grw5s2pf	685	16	stretch	stretch	NN
cord-256444-grw5s2pf	685	17	of	of	IN
cord-256444-grw5s2pf	685	18	sequence	sequence	NN
cord-256444-grw5s2pf	685	19	that	that	WDT
cord-256444-grw5s2pf	685	20	is	be	VBZ
cord-256444-grw5s2pf	685	21	nearly	nearly	RB
cord-256444-grw5s2pf	685	22	homologous	homologous	JJ
cord-256444-grw5s2pf	685	23	to	to	IN
cord-256444-grw5s2pf	685	24	the	the	DT
cord-256444-grw5s2pf	685	25	3	3	CD
cord-256444-grw5s2pf	685	26	'	'	NN
cord-256444-grw5s2pf	685	27	end	end	NN
cord-256444-grw5s2pf	685	28	of	of	IN
cord-256444-grw5s2pf	685	29	the	the	DT
cord-256444-grw5s2pf	685	30	leader	leader	NN
cord-256444-grw5s2pf	685	31	RNA	RNA	NNP
cord-256444-grw5s2pf	685	32	(	(	-LRB-
cord-256444-grw5s2pf	685	33	Budzilowicz	Budzilowicz	NNP
cord-256444-grw5s2pf	685	34	et	et	NNP
cord-256444-grw5s2pf	685	35	aZ.	az.	NN
cord-256444-grw5s2pf	685	36	,	,	,
cord-256444-grw5s2pf	685	37	1985	1985	CD
cord-256444-grw5s2pf	685	38	)	)	-RRB-
cord-256444-grw5s2pf	685	39	.	.	.
cord-256444-grw5s2pf	686	1	This	this	DT
cord-256444-grw5s2pf	686	2	sequence	sequence	NN
cord-256444-grw5s2pf	686	3	constitutes	constitute	VBZ
cord-256444-grw5s2pf	686	4	part	part	NN
cord-256444-grw5s2pf	686	5	of	of	IN
cord-256444-grw5s2pf	686	6	the	the	DT
cord-256444-grw5s2pf	686	7	signal	signal	NN
cord-256444-grw5s2pf	686	8	for	for	IN
cord-256444-grw5s2pf	686	9	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	686	10	mRNA	mRNA	NNP
cord-256444-grw5s2pf	686	11	transcription	transcription	NNP
cord-256444-grw5s2pf	686	12	(	(	-LRB-
cord-256444-grw5s2pf	686	13	Makino	Makino	NNP
cord-256444-grw5s2pf	686	14	et	et	NNP
cord-256444-grw5s2pf	686	15	al	al	NNP
cord-256444-grw5s2pf	686	16	.	.	NNP
cord-256444-grw5s2pf	686	17	,	,	,
cord-256444-grw5s2pf	686	18	1991	1991	CD
cord-256444-grw5s2pf	686	19	)	)	-RRB-
cord-256444-grw5s2pf	686	20	.	.	.
cord-256444-grw5s2pf	687	1	Sequence	sequence	NN
cord-256444-grw5s2pf	687	2	comparison	comparison	NN
cord-256444-grw5s2pf	687	3	of	of	IN
cord-256444-grw5s2pf	687	4	viral	viral	JJ
cord-256444-grw5s2pf	687	5	genomic	genomic	NNS
cord-256444-grw5s2pf	687	6	and	and	CC
cord-256444-grw5s2pf	687	7	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	687	8	suggests	suggest	VBZ
cord-256444-grw5s2pf	687	9	that	that	IN
cord-256444-grw5s2pf	687	10	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	687	11	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	687	12	are	be	VBP
cord-256444-grw5s2pf	687	13	derived	derive	VBN
cord-256444-grw5s2pf	687	14	by	by	IN
cord-256444-grw5s2pf	687	15	fusion	fusion	NN
cord-256444-grw5s2pf	687	16	of	of	IN
cord-256444-grw5s2pf	687	17	the	the	DT
cord-256444-grw5s2pf	687	18	5	5	CD
cord-256444-grw5s2pf	687	19	'	'	NN
cord-256444-grw5s2pf	687	20	end	end	NN
cord-256444-grw5s2pf	687	21	genomic	genomic	JJ
cord-256444-grw5s2pf	687	22	RNA	rna	NN
cord-256444-grw5s2pf	687	23	sequence	sequence	NN
cord-256444-grw5s2pf	687	24	(	(	-LRB-
cord-256444-grw5s2pf	687	25	leader	leader	NN
cord-256444-grw5s2pf	687	26	)	)	-RRB-
cord-256444-grw5s2pf	687	27	to	to	IN
cord-256444-grw5s2pf	687	28	the	the	DT
cord-256444-grw5s2pf	687	29	mRNA	mRNA	NNP
cord-256444-grw5s2pf	687	30	start	start	VB
cord-256444-grw5s2pf	687	31	sites	site	NNS
cord-256444-grw5s2pf	687	32	on	on	IN
cord-256444-grw5s2pf	687	33	the	the	DT
cord-256444-grw5s2pf	687	34	viral	viral	JJ
cord-256444-grw5s2pf	687	35	genomic	genomic	JJ
cord-256444-grw5s2pf	687	36	RNA	RNA	NNP
cord-256444-grw5s2pf	687	37	.	.	.
cord-256444-grw5s2pf	688	1	The	the	DT
cord-256444-grw5s2pf	688	2	mRNA	mrna	NN
cord-256444-grw5s2pf	688	3	start	start	NN
cord-256444-grw5s2pf	688	4	sites	site	NNS
cord-256444-grw5s2pf	688	5	are	be	VBP
cord-256444-grw5s2pf	688	6	usually	usually	RB
cord-256444-grw5s2pf	688	7	located	locate	VBN
cord-256444-grw5s2pf	688	8	between	between	IN
cord-256444-grw5s2pf	688	9	the	the	DT
cord-256444-grw5s2pf	688	10	genes	gene	NNS
cord-256444-grw5s2pf	688	11	;	;	:
cord-256444-grw5s2pf	688	12	hence	hence	RB
cord-256444-grw5s2pf	688	13	,	,	,
cord-256444-grw5s2pf	688	14	they	-PRON-	PRP
cord-256444-grw5s2pf	688	15	are	be	VBP
cord-256444-grw5s2pf	688	16	termed	term	VBN
cord-256444-grw5s2pf	688	17	intergenic	intergenic	JJ
cord-256444-grw5s2pf	688	18	(	(	-LRB-
cord-256444-grw5s2pf	688	19	IG	IG	NNP
cord-256444-grw5s2pf	688	20	)	)	-RRB-
cord-256444-grw5s2pf	688	21	sequences	sequence	NNS
cord-256444-grw5s2pf	688	22	.	.	.
cord-256444-grw5s2pf	689	1	However	however	RB
cord-256444-grw5s2pf	689	2	,	,	,
cord-256444-grw5s2pf	689	3	some	some	DT
cord-256444-grw5s2pf	689	4	of	of	IN
cord-256444-grw5s2pf	689	5	the	the	DT
cord-256444-grw5s2pf	689	6	IGs	ig	NNS
cord-256444-grw5s2pf	689	7	may	may	MD
cord-256444-grw5s2pf	689	8	overlap	overlap	VB
cord-256444-grw5s2pf	689	9	the	the	DT
cord-256444-grw5s2pf	689	10	coding	code	VBG
cord-256444-grw5s2pf	689	11	region	region	NN
cord-256444-grw5s2pf	689	12	of	of	IN
cord-256444-grw5s2pf	689	13	the	the	DT
cord-256444-grw5s2pf	689	14	upstream	upstream	JJ
cord-256444-grw5s2pf	689	15	gene	gene	NN
cord-256444-grw5s2pf	689	16	.	.	.
cord-256444-grw5s2pf	690	1	The	the	DT
cord-256444-grw5s2pf	690	2	core	core	NN
cord-256444-grw5s2pf	690	3	sequence	sequence	NN
cord-256444-grw5s2pf	690	4	of	of	IN
cord-256444-grw5s2pf	690	5	the	the	DT
cord-256444-grw5s2pf	690	6	IG	ig	NN
cord-256444-grw5s2pf	690	7	for	for	IN
cord-256444-grw5s2pf	690	8	MHV	MHV	NNP
cord-256444-grw5s2pf	690	9	is	be	VBZ
cord-256444-grw5s2pf	690	10	UCUAAAC	UCUAAAC	NNP
cord-256444-grw5s2pf	690	11	or	or	CC
cord-256444-grw5s2pf	690	12	a	a	DT
cord-256444-grw5s2pf	690	13	slightly	slightly	RB
cord-256444-grw5s2pf	690	14	variant	variant	JJ
cord-256444-grw5s2pf	690	15	form	form	NN
cord-256444-grw5s2pf	690	16	of	of	IN
cord-256444-grw5s2pf	690	17	this	this	DT
cord-256444-grw5s2pf	690	18	sequence	sequence	NN
cord-256444-grw5s2pf	690	19	at	at	IN
cord-256444-grw5s2pf	690	20	various	various	JJ
cord-256444-grw5s2pf	690	21	IG	ig	NN
cord-256444-grw5s2pf	690	22	sites	site	NNS
cord-256444-grw5s2pf	690	23	(	(	-LRB-
cord-256444-grw5s2pf	690	24	Joo	Joo	NNP
cord-256444-grw5s2pf	690	25	and	and	CC
cord-256444-grw5s2pf	690	26	Makino	Makino	NNP
cord-256444-grw5s2pf	690	27	,	,	,
cord-256444-grw5s2pf	690	28	1992	1992	CD
cord-256444-grw5s2pf	690	29	)	)	-RRB-
cord-256444-grw5s2pf	690	30	.	.	.
cord-256444-grw5s2pf	691	1	Other	other	JJ
cord-256444-grw5s2pf	691	2	virus	virus	NN
cord-256444-grw5s2pf	691	3	species	specie	NNS
cord-256444-grw5s2pf	691	4	also	also	RB
cord-256444-grw5s2pf	691	5	have	have	VBP
cord-256444-grw5s2pf	691	6	similar	similar	JJ
cord-256444-grw5s2pf	691	7	IG	ig	NN
cord-256444-grw5s2pf	691	8	sequences	sequence	NNS
cord-256444-grw5s2pf	691	9	.	.	.
cord-256444-grw5s2pf	692	1	The	the	DT
cord-256444-grw5s2pf	692	2	leader	leader	NN
cord-256444-grw5s2pf	692	3	sequence	sequence	NN
cord-256444-grw5s2pf	692	4	of	of	IN
cord-256444-grw5s2pf	692	5	MHV	MHV	NNP
cord-256444-grw5s2pf	692	6	ranges	range	VBZ
cord-256444-grw5s2pf	692	7	in	in	IN
cord-256444-grw5s2pf	692	8	length	length	NN
cord-256444-grw5s2pf	692	9	from	from	IN
cord-256444-grw5s2pf	692	10	72	72	CD
cord-256444-grw5s2pf	692	11	to	to	TO
cord-256444-grw5s2pf	692	12	82	82	CD
cord-256444-grw5s2pf	692	13	nucleotides	nucleotide	NNS
cord-256444-grw5s2pf	692	14	,	,	,
cord-256444-grw5s2pf	692	15	the	the	DT
cord-256444-grw5s2pf	692	16	variation	variation	NN
cord-256444-grw5s2pf	692	17	resulting	result	VBG
cord-256444-grw5s2pf	692	18	from	from	IN
cord-256444-grw5s2pf	692	19	the	the	DT
cord-256444-grw5s2pf	692	20	heterogeneity	heterogeneity	NN
cord-256444-grw5s2pf	692	21	of	of	IN
cord-256444-grw5s2pf	692	22	the	the	DT
cord-256444-grw5s2pf	692	23	3	3	CD
cord-256444-grw5s2pf	692	24	'	'	NN
cord-256444-grw5s2pf	692	25	end	end	NN
cord-256444-grw5s2pf	692	26	sequence	sequence	NN
cord-256444-grw5s2pf	692	27	,	,	,
cord-256444-grw5s2pf	692	28	which	which	WDT
cord-256444-grw5s2pf	692	29	contains	contain	VBZ
cord-256444-grw5s2pf	692	30	two	two	CD
cord-256444-grw5s2pf	692	31	to	to	TO
cord-256444-grw5s2pf	692	32	four	four	CD
cord-256444-grw5s2pf	692	33	copies	copy	NNS
cord-256444-grw5s2pf	692	34	of	of	IN
cord-256444-grw5s2pf	692	35	a	a	DT
cord-256444-grw5s2pf	692	36	pentanucleotide	pentanucleotide	NN
cord-256444-grw5s2pf	692	37	(	(	-LRB-
cord-256444-grw5s2pf	692	38	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	692	39	)	)	-RRB-
cord-256444-grw5s2pf	692	40	repeat	repeat	NN
cord-256444-grw5s2pf	692	41	.	.	.
cord-256444-grw5s2pf	693	1	The	the	DT
cord-256444-grw5s2pf	693	2	homologous	homologous	JJ
cord-256444-grw5s2pf	693	3	nucleotides	nucleotide	NNS
cord-256444-grw5s2pf	693	4	(	(	-LRB-
cord-256444-grw5s2pf	693	5	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	693	6	)	)	-RRB-
cord-256444-grw5s2pf	693	7	at	at	IN
cord-256444-grw5s2pf	693	8	the	the	DT
cord-256444-grw5s2pf	693	9	3	3	CD
cord-256444-grw5s2pf	693	10	'	'	NN
cord-256444-grw5s2pf	693	11	end	end	NN
cord-256444-grw5s2pf	693	12	of	of	IN
cord-256444-grw5s2pf	693	13	the	the	DT
cord-256444-grw5s2pf	693	14	leader	leader	NN
cord-256444-grw5s2pf	693	15	and	and	CC
cord-256444-grw5s2pf	693	16	IG	ig	NN
cord-256444-grw5s2pf	693	17	sites	site	NNS
cord-256444-grw5s2pf	693	18	serve	serve	VBP
cord-256444-grw5s2pf	693	19	as	as	IN
cord-256444-grw5s2pf	693	20	fusion	fusion	NN
cord-256444-grw5s2pf	693	21	sites	site	NNS
cord-256444-grw5s2pf	693	22	for	for	IN
cord-256444-grw5s2pf	693	23	the	the	DT
cord-256444-grw5s2pf	693	24	leader	leader	NN
cord-256444-grw5s2pf	693	25	and	and	CC
cord-256444-grw5s2pf	693	26	mRNAs	mrna	NNS
cord-256444-grw5s2pf	693	27	.	.	.
cord-256444-grw5s2pf	694	1	Some	some	DT
cord-256444-grw5s2pf	694	2	of	of	IN
cord-256444-grw5s2pf	694	3	the	the	DT
cord-256444-grw5s2pf	694	4	MHV	MHV	NNP
cord-256444-grw5s2pf	694	5	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	694	6	are	be	VBP
cord-256444-grw5s2pf	694	7	heterogeneous	heterogeneous	JJ
cord-256444-grw5s2pf	694	8	,	,	,
cord-256444-grw5s2pf	694	9	consisting	consist	VBG
cord-256444-grw5s2pf	694	10	of	of	IN
cord-256444-grw5s2pf	694	11	several	several	JJ
cord-256444-grw5s2pf	694	12	subspecies	subspecie	NNS
cord-256444-grw5s2pf	694	13	,	,	,
cord-256444-grw5s2pf	694	14	each	each	DT
cord-256444-grw5s2pf	694	15	containing	contain	VBG
cord-256444-grw5s2pf	694	16	different	different	JJ
cord-256444-grw5s2pf	694	17	copy	copy	NN
cord-256444-grw5s2pf	694	18	numbers	number	NNS
cord-256444-grw5s2pf	694	19	of	of	IN
cord-256444-grw5s2pf	694	20	the	the	DT
cord-256444-grw5s2pf	694	21	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	694	22	repeat	repeat	NN
cord-256444-grw5s2pf	694	23	.	.	.
cord-256444-grw5s2pf	695	1	This	this	DT
cord-256444-grw5s2pf	695	2	fact	fact	NN
cord-256444-grw5s2pf	695	3	suggests	suggest	VBZ
cord-256444-grw5s2pf	695	4	that	that	IN
cord-256444-grw5s2pf	695	5	the	the	DT
cord-256444-grw5s2pf	695	6	fusion	fusion	NN
cord-256444-grw5s2pf	695	7	between	between	IN
cord-256444-grw5s2pf	695	8	the	the	DT
cord-256444-grw5s2pf	695	9	leader	leader	NN
cord-256444-grw5s2pf	695	10	RNA	RNA	NNP
cord-256444-grw5s2pf	695	11	and	and	CC
cord-256444-grw5s2pf	695	12	the	the	DT
cord-256444-grw5s2pf	695	13	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	695	14	is	be	VBZ
cord-256444-grw5s2pf	695	15	not	not	RB
cord-256444-grw5s2pf	695	16	very	very	RB
cord-256444-grw5s2pf	695	17	precise	precise	JJ
cord-256444-grw5s2pf	695	18	.	.	.
cord-256444-grw5s2pf	696	1	The	the	DT
cord-256444-grw5s2pf	696	2	length	length	NN
cord-256444-grw5s2pf	696	3	and	and	CC
cord-256444-grw5s2pf	696	4	sequence	sequence	NN
cord-256444-grw5s2pf	696	5	of	of	IN
cord-256444-grw5s2pf	696	6	the	the	DT
cord-256444-grw5s2pf	696	7	leader	leader	NN
cord-256444-grw5s2pf	696	8	RNA	RNA	NNP
cord-256444-grw5s2pf	696	9	in	in	IN
cord-256444-grw5s2pf	696	10	other	other	JJ
cord-256444-grw5s2pf	696	11	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	696	12	vary	vary	VBP
cord-256444-grw5s2pf	696	13	.	.	.
cord-256444-grw5s2pf	697	1	However	however	RB
cord-256444-grw5s2pf	697	2	,	,	,
cord-256444-grw5s2pf	697	3	the	the	DT
cord-256444-grw5s2pf	697	4	3	3	CD
cord-256444-grw5s2pf	697	5	'	'	NN
cord-256444-grw5s2pf	697	6	end	end	NN
cord-256444-grw5s2pf	697	7	of	of	IN
cord-256444-grw5s2pf	697	8	the	the	DT
cord-256444-grw5s2pf	697	9	leader	leader	NN
cord-256444-grw5s2pf	697	10	sequence	sequence	NN
cord-256444-grw5s2pf	697	11	always	always	RB
cord-256444-grw5s2pf	697	12	contains	contain	VBZ
cord-256444-grw5s2pf	697	13	a	a	DT
cord-256444-grw5s2pf	697	14	pentanucleotide	pentanucleotide	JJ
cord-256444-grw5s2pf	697	15	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	697	16	or	or	CC
cord-256444-grw5s2pf	697	17	a	a	DT
cord-256444-grw5s2pf	697	18	closely	closely	RB
cord-256444-grw5s2pf	697	19	related	related	JJ
cord-256444-grw5s2pf	697	20	sequence	sequence	NN
cord-256444-grw5s2pf	697	21	.	.	.
cord-256444-grw5s2pf	698	1	mRNAs	mRNAs	NNP
cord-256444-grw5s2pf	698	2	of	of	IN
cord-256444-grw5s2pf	698	3	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	698	4	other	other	JJ
cord-256444-grw5s2pf	698	5	than	than	IN
cord-256444-grw5s2pf	698	6	MHV	MHV	NNP
cord-256444-grw5s2pf	698	7	are	be	VBP
cord-256444-grw5s2pf	698	8	usually	usually	RB
cord-256444-grw5s2pf	698	9	homogeneous	homogeneous	JJ
cord-256444-grw5s2pf	698	10	in	in	IN
cord-256444-grw5s2pf	698	11	their	-PRON-	PRP$
cord-256444-grw5s2pf	698	12	structure	structure	NN
cord-256444-grw5s2pf	698	13	,	,	,
cord-256444-grw5s2pf	699	1	probably	probably	RB
cord-256444-grw5s2pf	699	2	a	a	DT
cord-256444-grw5s2pf	699	3	reflection	reflection	NN
cord-256444-grw5s2pf	699	4	of	of	IN
cord-256444-grw5s2pf	699	5	the	the	DT
cord-256444-grw5s2pf	699	6	fact	fact	NN
cord-256444-grw5s2pf	699	7	that	that	IN
cord-256444-grw5s2pf	699	8	leader	leader	NN
cord-256444-grw5s2pf	699	9	RNA	RNA	NNP
cord-256444-grw5s2pf	699	10	at	at	IN
cord-256444-grw5s2pf	699	11	the	the	DT
cord-256444-grw5s2pf	699	12	5	5	CD
cord-256444-grw5s2pf	699	13	'	'	NN
cord-256444-grw5s2pf	699	14	end	end	NN
cord-256444-grw5s2pf	699	15	of	of	IN
cord-256444-grw5s2pf	699	16	the	the	DT
cord-256444-grw5s2pf	699	17	genome	genome	NN
cord-256444-grw5s2pf	699	18	and	and	CC
cord-256444-grw5s2pf	699	19	IG	IG	NNP
cord-256444-grw5s2pf	699	20	sites	site	NNS
cord-256444-grw5s2pf	699	21	in	in	IN
cord-256444-grw5s2pf	699	22	these	these	DT
cord-256444-grw5s2pf	699	23	viruses	virus	NNS
cord-256444-grw5s2pf	699	24	contain	contain	VBP
cord-256444-grw5s2pf	699	25	only	only	RB
cord-256444-grw5s2pf	699	26	a	a	DT
cord-256444-grw5s2pf	699	27	single	single	JJ
cord-256444-grw5s2pf	699	28	copy	copy	NN
cord-256444-grw5s2pf	699	29	of	of	IN
cord-256444-grw5s2pf	699	30	the	the	DT
cord-256444-grw5s2pf	699	31	the	the	DT
cord-256444-grw5s2pf	699	32	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	699	33	-	-	HYPH
cord-256444-grw5s2pf	699	34	like	like	JJ
cord-256444-grw5s2pf	699	35	sequence	sequence	NN
cord-256444-grw5s2pf	699	36	(	(	-LRB-
cord-256444-grw5s2pf	699	37	Hofmann	Hofmann	NNP
cord-256444-grw5s2pf	699	38	et	et	NNP
cord-256444-grw5s2pf	699	39	al	al	NNP
cord-256444-grw5s2pf	699	40	.	.	NNP
cord-256444-grw5s2pf	699	41	,	,	,
cord-256444-grw5s2pf	699	42	1993a	1993a	CD
cord-256444-grw5s2pf	699	43	)	)	-RRB-
cord-256444-grw5s2pf	699	44	.	.	.
cord-256444-grw5s2pf	700	1	The	the	DT
cord-256444-grw5s2pf	700	2	copy	copy	NN
cord-256444-grw5s2pf	700	3	number	number	NN
cord-256444-grw5s2pf	700	4	of	of	IN
cord-256444-grw5s2pf	700	5	this	this	DT
cord-256444-grw5s2pf	700	6	pentanucleotide	pentanucleotide	NN
cord-256444-grw5s2pf	700	7	repeat	repeat	NN
cord-256444-grw5s2pf	700	8	apparently	apparently	RB
cord-256444-grw5s2pf	700	9	plays	play	VBZ
cord-256444-grw5s2pf	700	10	an	an	DT
cord-256444-grw5s2pf	700	11	important	important	JJ
cord-256444-grw5s2pf	700	12	role	role	NN
cord-256444-grw5s2pf	700	13	in	in	IN
cord-256444-grw5s2pf	700	14	the	the	DT
cord-256444-grw5s2pf	700	15	regulation	regulation	NN
cord-256444-grw5s2pf	700	16	of	of	IN
cord-256444-grw5s2pf	700	17	mRNA	mRNA	NNP
cord-256444-grw5s2pf	700	18	transcription	transcription	NN
cord-256444-grw5s2pf	700	19	.	.	.
cord-256444-grw5s2pf	701	1	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	701	2	RNA	RNA	NNP
cord-256444-grw5s2pf	701	3	synthesis	synthesis	NN
cord-256444-grw5s2pf	701	4	is	be	VBZ
cord-256444-grw5s2pf	701	5	mediated	mediate	VBN
cord-256444-grw5s2pf	701	6	by	by	IN
cord-256444-grw5s2pf	701	7	RNA	RNA	NNP
cord-256444-grw5s2pf	701	8	-	-	HYPH
cord-256444-grw5s2pf	701	9	dependent	dependent	JJ
cord-256444-grw5s2pf	701	10	RNA	RNA	NNP
cord-256444-grw5s2pf	701	11	synthesis	synthesis	NN
cord-256444-grw5s2pf	701	12	via	via	IN
cord-256444-grw5s2pf	701	13	a	a	DT
cord-256444-grw5s2pf	701	14	negative	negative	JJ
cord-256444-grw5s2pf	701	15	-	-	HYPH
cord-256444-grw5s2pf	701	16	strand	strand	NN
cord-256444-grw5s2pf	701	17	RNA	RNA	NNP
cord-256444-grw5s2pf	701	18	intermediate	intermediate	JJ
cord-256444-grw5s2pf	701	19	(	(	-LRB-
cord-256444-grw5s2pf	701	20	complementary	complementary	JJ
cord-256444-grw5s2pf	701	21	to	to	IN
cord-256444-grw5s2pf	701	22	the	the	DT
cord-256444-grw5s2pf	701	23	genomic	genomic	JJ
cord-256444-grw5s2pf	701	24	RNA	RNA	NNP
cord-256444-grw5s2pf	701	25	)	)	-RRB-
cord-256444-grw5s2pf	701	26	.	.	.
cord-256444-grw5s2pf	702	1	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	702	2	negative	negative	JJ
cord-256444-grw5s2pf	702	3	-	-	HYPH
cord-256444-grw5s2pf	702	4	strand	strand	NN
cord-256444-grw5s2pf	702	5	RNA	RNA	NNP
cord-256444-grw5s2pf	702	6	represents	represent	VBZ
cord-256444-grw5s2pf	702	7	no	no	DT
cord-256444-grw5s2pf	702	8	more	more	JJR
cord-256444-grw5s2pf	702	9	than	than	IN
cord-256444-grw5s2pf	702	10	1	1	CD
cord-256444-grw5s2pf	702	11	-	-	SYM
cord-256444-grw5s2pf	702	12	2	2	CD
cord-256444-grw5s2pf	702	13	%	%	NN
cord-256444-grw5s2pf	702	14	of	of	IN
cord-256444-grw5s2pf	702	15	the	the	DT
cord-256444-grw5s2pf	702	16	total	total	JJ
cord-256444-grw5s2pf	702	17	intracellular	intracellular	JJ
cord-256444-grw5s2pf	702	18	virus	virus	NN
cord-256444-grw5s2pf	702	19	-	-	HYPH
cord-256444-grw5s2pf	702	20	specific	specific	JJ
cord-256444-grw5s2pf	702	21	RNA	RNA	NNP
cord-256444-grw5s2pf	702	22	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	702	23	and	and	CC
cord-256444-grw5s2pf	702	24	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	702	25	,	,	,
cord-256444-grw5s2pf	702	26	1986	1986	CD
cord-256444-grw5s2pf	702	27	)	)	-RRB-
cord-256444-grw5s2pf	702	28	.	.	.
cord-256444-grw5s2pf	703	1	Bothgenome	Bothgenome	NNP
cord-256444-grw5s2pf	703	2	-	-	HYPH
cord-256444-grw5s2pf	703	3	sized	sized	JJ
cord-256444-grw5s2pf	703	4	and	and	CC
cord-256444-grw5s2pf	703	5	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	703	6	negative	negative	JJ
cord-256444-grw5s2pf	703	7	-	-	HYPH
cord-256444-grw5s2pf	703	8	strand	strand	NN
cord-256444-grw5s2pf	703	9	RNAs	rna	NNS
cord-256444-grw5s2pf	703	10	,	,	,
cord-256444-grw5s2pf	703	11	which	which	WDT
cord-256444-grw5s2pf	703	12	correspond	correspond	VBP
cord-256444-grw5s2pf	703	13	in	in	IN
cord-256444-grw5s2pf	703	14	number	number	NN
cord-256444-grw5s2pf	703	15	of	of	IN
cord-256444-grw5s2pf	703	16	species	specie	NNS
cord-256444-grw5s2pf	703	17	and	and	CC
cord-256444-grw5s2pf	703	18	size	size	NN
cord-256444-grw5s2pf	703	19	to	to	IN
cord-256444-grw5s2pf	703	20	those	those	DT
cord-256444-grw5s2pf	703	21	of	of	IN
cord-256444-grw5s2pf	703	22	the	the	DT
cord-256444-grw5s2pf	703	23	virus	virus	NN
cord-256444-grw5s2pf	703	24	-	-	HYPH
cord-256444-grw5s2pf	703	25	specific	specific	JJ
cord-256444-grw5s2pf	703	26	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	703	27	,	,	,
cord-256444-grw5s2pf	703	28	have	have	VBP
cord-256444-grw5s2pf	703	29	been	be	VBN
cord-256444-grw5s2pf	703	30	detected	detect	VBN
cord-256444-grw5s2pf	703	31	(	(	-LRB-
cord-256444-grw5s2pf	703	32	Sethna	Sethna	NNP
cord-256444-grw5s2pf	703	33	et	et	NNP
cord-256444-grw5s2pf	703	34	al	al	NNP
cord-256444-grw5s2pf	703	35	.	.	.
cord-256444-grw5s2pf	704	1	,	,	,
cord-256444-grw5s2pf	704	2	1989	1989	CD
cord-256444-grw5s2pf	704	3	;	;	:
cord-256444-grw5s2pf	704	4	Hofmann	Hofmann	NNP
cord-256444-grw5s2pf	704	5	et	et	NNP
cord-256444-grw5s2pf	704	6	al	al	NNP
cord-256444-grw5s2pf	704	7	.	.	NNP
cord-256444-grw5s2pf	704	8	,	,	,
cord-256444-grw5s2pf	704	9	1990	1990	CD
cord-256444-grw5s2pf	704	10	)	)	-RRB-
cord-256444-grw5s2pf	704	11	.	.	.
cord-256444-grw5s2pf	705	1	The	the	DT
cord-256444-grw5s2pf	705	2	relative	relative	JJ
cord-256444-grw5s2pf	705	3	molar	molar	JJ
cord-256444-grw5s2pf	705	4	ratios	ratio	NNS
cord-256444-grw5s2pf	705	5	of	of	IN
cord-256444-grw5s2pf	705	6	the	the	DT
cord-256444-grw5s2pf	705	7	various	various	JJ
cord-256444-grw5s2pf	705	8	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	705	9	negative	negative	JJ
cord-256444-grw5s2pf	705	10	-	-	HYPH
cord-256444-grw5s2pf	705	11	strand	strand	NN
cord-256444-grw5s2pf	705	12	RNA	RNA	NNP
cord-256444-grw5s2pf	705	13	species	specie	NNS
cord-256444-grw5s2pf	705	14	are	be	VBP
cord-256444-grw5s2pf	705	15	comparable	comparable	JJ
cord-256444-grw5s2pf	705	16	to	to	IN
cord-256444-grw5s2pf	705	17	those	those	DT
cord-256444-grw5s2pf	705	18	of	of	IN
cord-256444-grw5s2pf	705	19	the	the	DT
cord-256444-grw5s2pf	705	20	positive	positive	JJ
cord-256444-grw5s2pf	705	21	-	-	HYPH
cord-256444-grw5s2pf	705	22	strand	strand	NN
cord-256444-grw5s2pf	705	23	subgenomic	subgenomic	NN
cord-256444-grw5s2pf	705	24	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	705	25	.	.	.
cord-256444-grw5s2pf	706	1	The	the	DT
cord-256444-grw5s2pf	706	2	5	5	CD
cord-256444-grw5s2pf	706	3	'	'	NN
cord-256444-grw5s2pf	706	4	end	end	NN
cord-256444-grw5s2pf	706	5	of	of	IN
cord-256444-grw5s2pf	706	6	the	the	DT
cord-256444-grw5s2pf	706	7	negativestrand	negativestrand	NN
cord-256444-grw5s2pf	706	8	RNA	RNA	NNP
cord-256444-grw5s2pf	706	9	contains	contain	VBZ
cord-256444-grw5s2pf	706	10	poly(U	poly(U	NNPS
cord-256444-grw5s2pf	706	11	)	)	-RRB-
cord-256444-grw5s2pf	706	12	sequences	sequence	NNS
cord-256444-grw5s2pf	706	13	,	,	,
cord-256444-grw5s2pf	706	14	which	which	WDT
cord-256444-grw5s2pf	706	15	are	be	VBP
cord-256444-grw5s2pf	706	16	shorter	short	JJR
cord-256444-grw5s2pf	706	17	than	than	IN
cord-256444-grw5s2pf	706	18	the	the	DT
cord-256444-grw5s2pf	706	19	poly(A	poly(a	JJ
cord-256444-grw5s2pf	706	20	)	)	-RRB-
cord-256444-grw5s2pf	707	1	sequences	sequence	NNS
cord-256444-grw5s2pf	707	2	present	present	JJ
cord-256444-grw5s2pf	707	3	on	on	IN
cord-256444-grw5s2pf	707	4	the	the	DT
cord-256444-grw5s2pf	707	5	positive	positive	JJ
cord-256444-grw5s2pf	707	6	-	-	HYPH
cord-256444-grw5s2pf	707	7	strand	strand	NN
cord-256444-grw5s2pf	707	8	RNAs	rna	NNS
cord-256444-grw5s2pf	707	9	.	.	.
cord-256444-grw5s2pf	708	1	At	at	IN
cord-256444-grw5s2pf	708	2	the	the	DT
cord-256444-grw5s2pf	708	3	3	3	CD
cord-256444-grw5s2pf	708	4	'	'	NN
cord-256444-grw5s2pf	708	5	end	end	NN
cord-256444-grw5s2pf	708	6	of	of	IN
cord-256444-grw5s2pf	708	7	the	the	DT
cord-256444-grw5s2pf	708	8	negative	negative	JJ
cord-256444-grw5s2pf	708	9	-	-	HYPH
cord-256444-grw5s2pf	708	10	strand	strand	NN
cord-256444-grw5s2pf	708	11	RNA	RNA	NNP
cord-256444-grw5s2pf	708	12	is	be	VBZ
cord-256444-grw5s2pf	708	13	the	the	DT
cord-256444-grw5s2pf	708	14	complementary	complementary	JJ
cord-256444-grw5s2pf	708	15	sequence	sequence	NN
cord-256444-grw5s2pf	708	16	of	of	IN
cord-256444-grw5s2pf	708	17	the	the	DT
cord-256444-grw5s2pf	708	18	leader	leader	NN
cord-256444-grw5s2pf	708	19	RNA	RNA	NNP
cord-256444-grw5s2pf	708	20	(	(	-LRB-
cord-256444-grw5s2pf	708	21	anti	anti	JJ
cord-256444-grw5s2pf	708	22	-	-	NN
cord-256444-grw5s2pf	708	23	leader	leader	NN
cord-256444-grw5s2pf	708	24	)	)	-RRB-
cord-256444-grw5s2pf	709	1	(	(	-LRB-
cord-256444-grw5s2pf	709	2	Sethna	Sethna	NNP
cord-256444-grw5s2pf	709	3	et	et	NNP
cord-256444-grw5s2pf	709	4	al	al	NNP
cord-256444-grw5s2pf	709	5	.	.	NNP
cord-256444-grw5s2pf	709	6	,	,	,
cord-256444-grw5s2pf	709	7	1991	1991	CD
cord-256444-grw5s2pf	709	8	)	)	-RRB-
cord-256444-grw5s2pf	709	9	.	.	.
cord-256444-grw5s2pf	710	1	Structurally	structurally	RB
cord-256444-grw5s2pf	710	2	speaking	speak	VBG
cord-256444-grw5s2pf	710	3	,	,	,
cord-256444-grw5s2pf	710	4	the	the	DT
cord-256444-grw5s2pf	710	5	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	710	6	negative	negative	JJ
cord-256444-grw5s2pf	710	7	-	-	HYPH
cord-256444-grw5s2pf	710	8	strand	strand	NN
cord-256444-grw5s2pf	710	9	RNAs	rna	NNS
cord-256444-grw5s2pf	710	10	appear	appear	VBP
cord-256444-grw5s2pf	710	11	to	to	TO
cord-256444-grw5s2pf	710	12	be	be	VB
cord-256444-grw5s2pf	710	13	mirror	mirror	NN
cord-256444-grw5s2pf	710	14	images	image	NNS
cord-256444-grw5s2pf	710	15	of	of	IN
cord-256444-grw5s2pf	710	16	the	the	DT
cord-256444-grw5s2pf	710	17	positive	positive	JJ
cord-256444-grw5s2pf	710	18	-	-	HYPH
cord-256444-grw5s2pf	710	19	strand	strand	NN
cord-256444-grw5s2pf	710	20	subgenomic	subgenomic	NN
cord-256444-grw5s2pf	710	21	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	710	22	.	.	.
cord-256444-grw5s2pf	711	1	All	all	DT
cord-256444-grw5s2pf	711	2	of	of	IN
cord-256444-grw5s2pf	711	3	the	the	DT
cord-256444-grw5s2pf	711	4	negative	negative	JJ
cord-256444-grw5s2pf	711	5	-	-	HYPH
cord-256444-grw5s2pf	711	6	strand	strand	NN
cord-256444-grw5s2pf	711	7	RNAs	rna	NNS
cord-256444-grw5s2pf	711	8	in	in	IN
cord-256444-grw5s2pf	711	9	the	the	DT
cord-256444-grw5s2pf	711	10	infected	infected	JJ
cord-256444-grw5s2pf	711	11	cells	cell	NNS
cord-256444-grw5s2pf	711	12	are	be	VBP
cord-256444-grw5s2pf	711	13	present	present	JJ
cord-256444-grw5s2pf	711	14	in	in	IN
cord-256444-grw5s2pf	711	15	the	the	DT
cord-256444-grw5s2pf	711	16	form	form	NN
cord-256444-grw5s2pf	711	17	of	of	IN
cord-256444-grw5s2pf	711	18	double	double	RB
cord-256444-grw5s2pf	711	19	-	-	HYPH
cord-256444-grw5s2pf	711	20	stranded	strand	VBN
cord-256444-grw5s2pf	711	21	RNA	RNA	NNP
cord-256444-grw5s2pf	711	22	,	,	,
cord-256444-grw5s2pf	711	23	no	no	DT
cord-256444-grw5s2pf	711	24	free	free	JJ
cord-256444-grw5s2pf	711	25	negative	negative	JJ
cord-256444-grw5s2pf	711	26	-	-	HYPH
cord-256444-grw5s2pf	711	27	strand	strand	NN
cord-256444-grw5s2pf	711	28	RNA	RNA	NNP
cord-256444-grw5s2pf	711	29	is	be	VBZ
cord-256444-grw5s2pf	711	30	detected	detect	VBN
cord-256444-grw5s2pf	711	31	.	.	.
cord-256444-grw5s2pf	712	1	In	in	IN
cord-256444-grw5s2pf	712	2	virus	virus	NN
cord-256444-grw5s2pf	712	3	-	-	HYPH
cord-256444-grw5s2pf	712	4	infected	infect	VBN
cord-256444-grw5s2pf	712	5	cells	cell	NNS
cord-256444-grw5s2pf	712	6	,	,	,
cord-256444-grw5s2pf	712	7	virus	virus	NN
cord-256444-grw5s2pf	712	8	-	-	HYPH
cord-256444-grw5s2pf	712	9	specific	specific	JJ
cord-256444-grw5s2pf	712	10	mRNA	mrna	NN
cord-256444-grw5s2pf	712	11	synthesis	synthesis	NN
cord-256444-grw5s2pf	712	12	can	can	MD
cord-256444-grw5s2pf	712	13	usually	usually	RB
cord-256444-grw5s2pf	712	14	be	be	VB
cord-256444-grw5s2pf	712	15	detected	detect	VBN
cord-256444-grw5s2pf	712	16	a	a	DT
cord-256444-grw5s2pf	712	17	few	few	JJ
cord-256444-grw5s2pf	712	18	hours	hour	NNS
cord-256444-grw5s2pf	712	19	after	after	IN
cord-256444-grw5s2pf	712	20	infection	infection	NN
cord-256444-grw5s2pf	712	21	and	and	CC
cord-256444-grw5s2pf	712	22	throughout	throughout	IN
cord-256444-grw5s2pf	712	23	most	most	JJS
cord-256444-grw5s2pf	712	24	of	of	IN
cord-256444-grw5s2pf	712	25	the	the	DT
cord-256444-grw5s2pf	712	26	viral	viral	JJ
cord-256444-grw5s2pf	712	27	replication	replication	NN
cord-256444-grw5s2pf	712	28	cycle	cycle	NN
cord-256444-grw5s2pf	712	29	(	(	-LRB-
cord-256444-grw5s2pf	712	30	Stern	Stern	NNP
cord-256444-grw5s2pf	712	31	and	and	CC
cord-256444-grw5s2pf	712	32	Kennedy	Kennedy	NNP
cord-256444-grw5s2pf	712	33	,	,	,
cord-256444-grw5s2pf	712	34	1980a	1980a	CD
cord-256444-grw5s2pf	712	35	;	;	:
cord-256444-grw5s2pf	712	36	Leibowitz	Leibowitz	NNP
cord-256444-grw5s2pf	712	37	et	et	NNP
cord-256444-grw5s2pf	712	38	al	al	NNP
cord-256444-grw5s2pf	712	39	.	.	.
cord-256444-grw5s2pf	713	1	,	,	,
cord-256444-grw5s2pf	713	2	1981	1981	CD
cord-256444-grw5s2pf	713	3	;	;	:
cord-256444-grw5s2pf	713	4	Keck	Keck	NNP
cord-256444-grw5s2pf	713	5	et	et	NNP
cord-256444-grw5s2pf	713	6	al	al	NNP
cord-256444-grw5s2pf	713	7	.	.	NNP
cord-256444-grw5s2pf	713	8	,	,	,
cord-256444-grw5s2pf	713	9	1988a	1988a	CD
cord-256444-grw5s2pf	713	10	)	)	-RRB-
cord-256444-grw5s2pf	713	11	.	.	.
cord-256444-grw5s2pf	714	1	The	the	DT
cord-256444-grw5s2pf	714	2	molar	molar	JJ
cord-256444-grw5s2pf	714	3	amounts	amount	NNS
cord-256444-grw5s2pf	714	4	of	of	IN
cord-256444-grw5s2pf	714	5	the	the	DT
cord-256444-grw5s2pf	714	6	different	different	JJ
cord-256444-grw5s2pf	714	7	mRNA	mRNA	NNP
cord-256444-grw5s2pf	714	8	species	specie	NNS
cord-256444-grw5s2pf	714	9	vary	vary	VBP
cord-256444-grw5s2pf	714	10	;	;	:
cord-256444-grw5s2pf	714	11	smaller	small	JJR
cord-256444-grw5s2pf	714	12	mRNAs	mrna	NNS
cord-256444-grw5s2pf	714	13	are	be	VBP
cord-256444-grw5s2pf	714	14	generally	generally	RB
cord-256444-grw5s2pf	714	15	more	more	RBR
cord-256444-grw5s2pf	714	16	abundant	abundant	JJ
cord-256444-grw5s2pf	714	17	than	than	IN
cord-256444-grw5s2pf	714	18	larger	large	JJR
cord-256444-grw5s2pf	714	19	ones	one	NNS
cord-256444-grw5s2pf	714	20	,	,	,
cord-256444-grw5s2pf	714	21	but	but	CC
cord-256444-grw5s2pf	714	22	this	this	DT
cord-256444-grw5s2pf	714	23	rule	rule	NN
cord-256444-grw5s2pf	714	24	does	do	VBZ
cord-256444-grw5s2pf	714	25	not	not	RB
cord-256444-grw5s2pf	714	26	always	always	RB
cord-256444-grw5s2pf	714	27	hold	hold	VB
cord-256444-grw5s2pf	714	28	true	true	JJ
cord-256444-grw5s2pf	714	29	.	.	.
cord-256444-grw5s2pf	715	1	Nevertheless	nevertheless	RB
cord-256444-grw5s2pf	715	2	,	,	,
cord-256444-grw5s2pf	715	3	the	the	DT
cord-256444-grw5s2pf	715	4	relative	relative	JJ
cord-256444-grw5s2pf	715	5	ratio	ratio	NN
cord-256444-grw5s2pf	715	6	of	of	IN
cord-256444-grw5s2pf	715	7	different	different	JJ
cord-256444-grw5s2pf	715	8	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	715	9	mRNA	mRNA	NNP
cord-256444-grw5s2pf	715	10	species	species	NN
cord-256444-grw5s2pf	715	11	remains	remain	VBZ
cord-256444-grw5s2pf	715	12	constant	constant	JJ
cord-256444-grw5s2pf	715	13	throughout	throughout	IN
cord-256444-grw5s2pf	715	14	,	,	,
cord-256444-grw5s2pf	715	15	suggesting	suggest	VBG
cord-256444-grw5s2pf	715	16	that	that	IN
cord-256444-grw5s2pf	715	17	the	the	DT
cord-256444-grw5s2pf	715	18	synthesis	synthesis	NN
cord-256444-grw5s2pf	715	19	of	of	IN
cord-256444-grw5s2pf	715	20	the	the	DT
cord-256444-grw5s2pf	715	21	various	various	JJ
cord-256444-grw5s2pf	715	22	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	715	23	mRNA	mRNA	NNP
cord-256444-grw5s2pf	715	24	species	specie	NNS
cord-256444-grw5s2pf	715	25	is	be	VBZ
cord-256444-grw5s2pf	715	26	regulated	regulate	VBN
cord-256444-grw5s2pf	715	27	coordinately	coordinately	RB
cord-256444-grw5s2pf	715	28	.	.	.
cord-256444-grw5s2pf	716	1	Some	some	DT
cord-256444-grw5s2pf	716	2	viruses	virus	NNS
cord-256444-grw5s2pf	716	3	may	may	MD
cord-256444-grw5s2pf	716	4	show	show	VB
cord-256444-grw5s2pf	716	5	slight	slight	JJ
cord-256444-grw5s2pf	716	6	variations	variation	NNS
cord-256444-grw5s2pf	716	7	in	in	IN
cord-256444-grw5s2pf	716	8	the	the	DT
cord-256444-grw5s2pf	716	9	amounts	amount	NNS
cord-256444-grw5s2pf	716	10	of	of	IN
cord-256444-grw5s2pf	716	11	individual	individual	JJ
cord-256444-grw5s2pf	716	12	mRNA	mrna	NN
cord-256444-grw5s2pf	716	13	species	specie	NNS
cord-256444-grw5s2pf	716	14	present	present	JJ
cord-256444-grw5s2pf	716	15	during	during	IN
cord-256444-grw5s2pf	716	16	infection	infection	NN
cord-256444-grw5s2pf	716	17	(	(	-LRB-
cord-256444-grw5s2pf	716	18	Hiscox	Hiscox	NNP
cord-256444-grw5s2pf	716	19	et	et	FW
cord-256444-grw5s2pf	716	20	al	al	NNP
cord-256444-grw5s2pf	716	21	.	.	NNP
cord-256444-grw5s2pf	716	22	,	,	,
cord-256444-grw5s2pf	716	23	1995a	1995a	CD
cord-256444-grw5s2pf	716	24	)	)	-RRB-
cord-256444-grw5s2pf	716	25	.	.	.
cord-256444-grw5s2pf	717	1	Later	later	RB
cord-256444-grw5s2pf	717	2	in	in	IN
cord-256444-grw5s2pf	717	3	infection	infection	NN
cord-256444-grw5s2pf	717	4	,	,	,
cord-256444-grw5s2pf	717	5	there	there	EX
cord-256444-grw5s2pf	717	6	appears	appear	VBZ
cord-256444-grw5s2pf	717	7	to	to	TO
cord-256444-grw5s2pf	717	8	be	be	VB
cord-256444-grw5s2pf	717	9	an	an	DT
cord-256444-grw5s2pf	717	10	enhanced	enhanced	JJ
cord-256444-grw5s2pf	717	11	synthesis	synthesis	NN
cord-256444-grw5s2pf	717	12	of	of	IN
cord-256444-grw5s2pf	717	13	the	the	DT
cord-256444-grw5s2pf	717	14	genomic	genomic	JJ
cord-256444-grw5s2pf	717	15	-	-	HYPH
cord-256444-grw5s2pf	717	16	sized	sized	JJ
cord-256444-grw5s2pf	717	17	RNA	RNA	NNP
cord-256444-grw5s2pf	717	18	(	(	-LRB-
cord-256444-grw5s2pf	717	19	Keck	Keck	NNP
cord-256444-grw5s2pf	717	20	et	et	NNP
cord-256444-grw5s2pf	717	21	al	al	NNP
cord-256444-grw5s2pf	717	22	.	.	NNP
cord-256444-grw5s2pf	717	23	,	,	,
cord-256444-grw5s2pf	717	24	1988a	1988a	CD
cord-256444-grw5s2pf	717	25	)	)	-RRB-
cord-256444-grw5s2pf	717	26	.	.	.
cord-256444-grw5s2pf	718	1	The	the	DT
cord-256444-grw5s2pf	718	2	kinetics	kinetic	NNS
cord-256444-grw5s2pf	718	3	of	of	IN
cord-256444-grw5s2pf	718	4	negative	negative	JJ
cord-256444-grw5s2pf	718	5	-	-	HYPH
cord-256444-grw5s2pf	718	6	strand	strand	NN
cord-256444-grw5s2pf	718	7	RNA	RNA	NNP
cord-256444-grw5s2pf	718	8	synthesis	synthesis	NN
cord-256444-grw5s2pf	718	9	follows	follow	VBZ
cord-256444-grw5s2pf	718	10	a	a	DT
cord-256444-grw5s2pf	718	11	pattern	pattern	NN
cord-256444-grw5s2pf	718	12	similar	similar	JJ
cord-256444-grw5s2pf	718	13	to	to	IN
cord-256444-grw5s2pf	718	14	that	that	DT
cord-256444-grw5s2pf	718	15	of	of	IN
cord-256444-grw5s2pf	718	16	positive	positive	JJ
cord-256444-grw5s2pf	718	17	-	-	HYPH
cord-256444-grw5s2pf	718	18	strand	strand	NN
cord-256444-grw5s2pf	718	19	mRNA	mrna	NN
cord-256444-grw5s2pf	718	20	synthesis	synthesis	NN
cord-256444-grw5s2pf	718	21	;	;	:
cord-256444-grw5s2pf	718	22	however	however	RB
cord-256444-grw5s2pf	718	23	,	,	,
cord-256444-grw5s2pf	718	24	the	the	DT
cord-256444-grw5s2pf	718	25	peak	peak	NN
cord-256444-grw5s2pf	718	26	of	of	IN
cord-256444-grw5s2pf	718	27	negative	negative	JJ
cord-256444-grw5s2pf	718	28	-	-	HYPH
cord-256444-grw5s2pf	718	29	strand	strand	NN
cord-256444-grw5s2pf	718	30	RNA	RNA	NNP
cord-256444-grw5s2pf	718	31	synthesis	synthesis	NN
cord-256444-grw5s2pf	718	32	appears	appear	VBZ
cord-256444-grw5s2pf	718	33	to	to	TO
cord-256444-grw5s2pf	718	34	occur	occur	VB
cord-256444-grw5s2pf	718	35	earlier	early	RBR
cord-256444-grw5s2pf	718	36	than	than	IN
cord-256444-grw5s2pf	718	37	for	for	IN
cord-256444-grw5s2pf	718	38	positive	positive	JJ
cord-256444-grw5s2pf	718	39	-	-	HYPH
cord-256444-grw5s2pf	718	40	strand	strand	NN
cord-256444-grw5s2pf	718	41	RNA	RNA	NNP
cord-256444-grw5s2pf	718	42	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	718	43	and	and	CC
cord-256444-grw5s2pf	718	44	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	718	45	,	,	,
cord-256444-grw5s2pf	718	46	1986	1986	CD
cord-256444-grw5s2pf	718	47	)	)	-RRB-
cord-256444-grw5s2pf	718	48	.	.	.
cord-256444-grw5s2pf	719	1	Thereafter	thereafter	RB
cord-256444-grw5s2pf	719	2	,	,	,
cord-256444-grw5s2pf	719	3	negative	negative	JJ
cord-256444-grw5s2pf	719	4	-	-	HYPH
cord-256444-grw5s2pf	719	5	strand	strand	NN
cord-256444-grw5s2pf	719	6	RNA	RNA	NNP
cord-256444-grw5s2pf	719	7	synthesis	synthesis	NN
cord-256444-grw5s2pf	719	8	drops	drop	VBZ
cord-256444-grw5s2pf	719	9	significantly	significantly	RB
cord-256444-grw5s2pf	719	10	,	,	,
cord-256444-grw5s2pf	719	11	in	in	IN
cord-256444-grw5s2pf	719	12	contrast	contrast	NN
cord-256444-grw5s2pf	719	13	to	to	IN
cord-256444-grw5s2pf	719	14	that	that	DT
cord-256444-grw5s2pf	719	15	of	of	IN
cord-256444-grw5s2pf	719	16	positive	positive	JJ
cord-256444-grw5s2pf	719	17	-	-	HYPH
cord-256444-grw5s2pf	719	18	strand	strand	NN
cord-256444-grw5s2pf	719	19	RNA	RNA	NNP
cord-256444-grw5s2pf	719	20	synthesis	synthesis	NN
cord-256444-grw5s2pf	719	21	,	,	,
cord-256444-grw5s2pf	719	22	and	and	CC
cord-256444-grw5s2pf	720	1	negative	negative	JJ
cord-256444-grw5s2pf	720	2	-	-	HYPH
cord-256444-grw5s2pf	720	3	strand	strand	NN
cord-256444-grw5s2pf	720	4	RNA	RNA	NNP
cord-256444-grw5s2pf	720	5	appears	appear	VBZ
cord-256444-grw5s2pf	720	6	to	to	TO
cord-256444-grw5s2pf	720	7	be	be	VB
cord-256444-grw5s2pf	720	8	stable	stable	JJ
cord-256444-grw5s2pf	720	9	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	720	10	and	and	CC
cord-256444-grw5s2pf	720	11	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	720	12	,	,	,
cord-256444-grw5s2pf	720	13	1986	1986	CD
cord-256444-grw5s2pf	720	14	)	)	-RRB-
cord-256444-grw5s2pf	720	15	.	.	.
cord-256444-grw5s2pf	721	1	A	a	DT
cord-256444-grw5s2pf	721	2	similar	similar	JJ
cord-256444-grw5s2pf	721	3	pattern	pattern	NN
cord-256444-grw5s2pf	721	4	of	of	IN
cord-256444-grw5s2pf	721	5	kinetics	kinetic	NNS
cord-256444-grw5s2pf	721	6	of	of	IN
cord-256444-grw5s2pf	721	7	negative	negative	JJ
cord-256444-grw5s2pf	721	8	-	-	HYPH
cord-256444-grw5s2pf	721	9	strand	strand	NN
cord-256444-grw5s2pf	721	10	RNA	RNA	NNP
cord-256444-grw5s2pf	721	11	synthesis	synthesis	NN
cord-256444-grw5s2pf	721	12	is	be	VBZ
cord-256444-grw5s2pf	721	13	also	also	RB
cord-256444-grw5s2pf	721	14	seen	see	VBN
cord-256444-grw5s2pf	721	15	in	in	IN
cord-256444-grw5s2pf	721	16	the	the	DT
cord-256444-grw5s2pf	721	17	accumulation	accumulation	NN
cord-256444-grw5s2pf	721	18	of	of	IN
cord-256444-grw5s2pf	721	19	the	the	DT
cord-256444-grw5s2pf	721	20	negative	negative	JJ
cord-256444-grw5s2pf	721	21	-	-	HYPH
cord-256444-grw5s2pf	721	22	strand	strand	NN
cord-256444-grw5s2pf	721	23	RNA	RNA	NNP
cord-256444-grw5s2pf	721	24	of	of	IN
cord-256444-grw5s2pf	721	25	a	a	DT
cord-256444-grw5s2pf	721	26	DI	DI	NNP
cord-256444-grw5s2pf	721	27	RNA	RNA	NNP
cord-256444-grw5s2pf	721	28	,	,	,
cord-256444-grw5s2pf	721	29	which	which	WDT
cord-256444-grw5s2pf	721	30	very	very	RB
cord-256444-grw5s2pf	721	31	rapidly	rapidly	RB
cord-256444-grw5s2pf	721	32	reaches	reach	VBZ
cord-256444-grw5s2pf	721	33	a	a	DT
cord-256444-grw5s2pf	721	34	steady	steady	JJ
cord-256444-grw5s2pf	721	35	-	-	HYPH
cord-256444-grw5s2pf	721	36	state	state	NN
cord-256444-grw5s2pf	721	37	level	level	NN
cord-256444-grw5s2pf	721	38	after	after	IN
cord-256444-grw5s2pf	721	39	transfection	transfection	NN
cord-256444-grw5s2pf	721	40	.	.	.
cord-256444-grw5s2pf	722	1	Therefore	therefore	RB
cord-256444-grw5s2pf	722	2	,	,	,
cord-256444-grw5s2pf	722	3	the	the	DT
cord-256444-grw5s2pf	722	4	negative	negative	JJ
cord-256444-grw5s2pf	722	5	-	-	HYPH
cord-256444-grw5s2pf	722	6	strand	strand	NN
cord-256444-grw5s2pf	722	7	RNA	RNA	NNP
cord-256444-grw5s2pf	722	8	probably	probably	RB
cord-256444-grw5s2pf	722	9	functions	function	VBZ
cord-256444-grw5s2pf	722	10	as	as	IN
cord-256444-grw5s2pf	722	11	a	a	DT
cord-256444-grw5s2pf	722	12	template	template	NN
cord-256444-grw5s2pf	722	13	for	for	IN
cord-256444-grw5s2pf	722	14	multiple	multiple	JJ
cord-256444-grw5s2pf	722	15	rounds	round	NNS
cord-256444-grw5s2pf	722	16	of	of	IN
cord-256444-grw5s2pf	722	17	positive	positive	JJ
cord-256444-grw5s2pf	722	18	-	-	HYPH
cord-256444-grw5s2pf	722	19	strand	strand	NN
cord-256444-grw5s2pf	722	20	RNA	RNA	NNP
cord-256444-grw5s2pf	722	21	synthesis	synthesis	NN
cord-256444-grw5s2pf	722	22	.	.	.
cord-256444-grw5s2pf	723	1	This	this	DT
cord-256444-grw5s2pf	723	2	conclusion	conclusion	NN
cord-256444-grw5s2pf	723	3	is	be	VBZ
cord-256444-grw5s2pf	723	4	supported	support	VBN
cord-256444-grw5s2pf	723	5	by	by	IN
cord-256444-grw5s2pf	723	6	the	the	DT
cord-256444-grw5s2pf	723	7	study	study	NN
cord-256444-grw5s2pf	723	8	of	of	IN
cord-256444-grw5s2pf	723	9	a	a	DT
cord-256444-grw5s2pf	723	10	ts	ts	JJ
cord-256444-grw5s2pf	723	11	mutant	mutant	NN
cord-256444-grw5s2pf	723	12	defective	defective	JJ
cord-256444-grw5s2pf	723	13	in	in	IN
cord-256444-grw5s2pf	723	14	negative	negative	JJ
cord-256444-grw5s2pf	723	15	-	-	HYPH
cord-256444-grw5s2pf	723	16	strand	strand	NN
cord-256444-grw5s2pf	723	17	RNA	RNA	NNP
cord-256444-grw5s2pf	723	18	synthesis	synthesis	NN
cord-256444-grw5s2pf	723	19	(	(	-LRB-
cord-256444-grw5s2pf	723	20	Schaad	Schaad	NNP
cord-256444-grw5s2pf	723	21	and	and	CC
cord-256444-grw5s2pf	723	22	Baric	Baric	NNP
cord-256444-grw5s2pf	723	23	,	,	,
cord-256444-grw5s2pf	723	24	1994	1994	CD
cord-256444-grw5s2pf	723	25	)	)	-RRB-
cord-256444-grw5s2pf	723	26	.	.	.
cord-256444-grw5s2pf	724	1	However	however	RB
cord-256444-grw5s2pf	724	2	,	,	,
cord-256444-grw5s2pf	724	3	the	the	DT
cord-256444-grw5s2pf	724	4	ability	ability	NN
cord-256444-grw5s2pf	724	5	to	to	TO
cord-256444-grw5s2pf	724	6	synthesize	synthesize	VB
cord-256444-grw5s2pf	724	7	negative	negative	JJ
cord-256444-grw5s2pf	724	8	-	-	HYPH
cord-256444-grw5s2pf	724	9	strand	strand	NN
cord-256444-grw5s2pf	724	10	RNA	RNA	NNP
cord-256444-grw5s2pf	724	11	seems	seem	VBZ
cord-256444-grw5s2pf	724	12	to	to	TO
cord-256444-grw5s2pf	724	13	be	be	VB
cord-256444-grw5s2pf	724	14	maintained	maintain	VBN
cord-256444-grw5s2pf	724	15	throughout	throughout	IN
cord-256444-grw5s2pf	724	16	the	the	DT
cord-256444-grw5s2pf	724	17	viral	viral	JJ
cord-256444-grw5s2pf	724	18	life	life	NN
cord-256444-grw5s2pf	724	19	cycle	cycle	NN
cord-256444-grw5s2pf	724	20	,	,	,
cord-256444-grw5s2pf	724	21	as	as	IN
cord-256444-grw5s2pf	724	22	evidenced	evidence	VBN
cord-256444-grw5s2pf	724	23	by	by	IN
cord-256444-grw5s2pf	724	24	the	the	DT
cord-256444-grw5s2pf	724	25	finding	finding	NN
cord-256444-grw5s2pf	724	26	that	that	IN
cord-256444-grw5s2pf	724	27	a	a	DT
cord-256444-grw5s2pf	724	28	transfected	transfecte	VBN
cord-256444-grw5s2pf	724	29	DI	DI	NNP
cord-256444-grw5s2pf	724	30	RNA	RNA	NNP
cord-256444-grw5s2pf	724	31	can	can	MD
cord-256444-grw5s2pf	724	32	replicate	replicate	VB
cord-256444-grw5s2pf	724	33	even	even	RB
cord-256444-grw5s2pf	724	34	when	when	WRB
cord-256444-grw5s2pf	724	35	transfected	transfecte	VBN
cord-256444-grw5s2pf	724	36	late	late	RB
cord-256444-grw5s2pf	724	37	in	in	IN
cord-256444-grw5s2pf	724	38	the	the	DT
cord-256444-grw5s2pf	724	39	infection	infection	NN
cord-256444-grw5s2pf	724	40	(	(	-LRB-
cord-256444-grw5s2pf	724	41	Jeong	Jeong	NNP
cord-256444-grw5s2pf	724	42	and	and	CC
cord-256444-grw5s2pf	724	43	Makino	Makino	NNP
cord-256444-grw5s2pf	724	44	,	,	,
cord-256444-grw5s2pf	724	45	1992	1992	CD
cord-256444-grw5s2pf	724	46	)	)	-RRB-
cord-256444-grw5s2pf	724	47	.	.	.
cord-256444-grw5s2pf	725	1	Since	since	IN
cord-256444-grw5s2pf	725	2	all	all	DT
cord-256444-grw5s2pf	725	3	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	725	4	RNAs	rna	NNS
cord-256444-grw5s2pf	725	5	consist	consist	VBP
cord-256444-grw5s2pf	725	6	of	of	IN
cord-256444-grw5s2pf	725	7	a	a	DT
cord-256444-grw5s2pf	725	8	leader	leader	NN
cord-256444-grw5s2pf	725	9	RNA	RNA	NNP
cord-256444-grw5s2pf	725	10	derived	derive	VBD
cord-256444-grw5s2pf	725	11	from	from	IN
cord-256444-grw5s2pf	725	12	the	the	DT
cord-256444-grw5s2pf	725	13	5	5	CD
cord-256444-grw5s2pf	725	14	'	'	NN
cord-256444-grw5s2pf	725	15	end	end	NN
cord-256444-grw5s2pf	725	16	of	of	IN
cord-256444-grw5s2pf	725	17	the	the	DT
cord-256444-grw5s2pf	725	18	genome	genome	NN
cord-256444-grw5s2pf	725	19	and	and	CC
cord-256444-grw5s2pf	725	20	a	a	DT
cord-256444-grw5s2pf	725	21	body	body	NN
cord-256444-grw5s2pf	725	22	sequence	sequence	NN
cord-256444-grw5s2pf	725	23	derived	derive	VBN
cord-256444-grw5s2pf	725	24	from	from	IN
cord-256444-grw5s2pf	725	25	various	various	JJ
cord-256444-grw5s2pf	725	26	downstream	downstream	JJ
cord-256444-grw5s2pf	725	27	sequences	sequence	NNS
cord-256444-grw5s2pf	725	28	,	,	,
cord-256444-grw5s2pf	725	29	they	-PRON-	PRP
cord-256444-grw5s2pf	725	30	must	must	MD
cord-256444-grw5s2pf	725	31	be	be	VB
cord-256444-grw5s2pf	725	32	synthesized	synthesize	VBN
cord-256444-grw5s2pf	725	33	by	by	IN
cord-256444-grw5s2pf	725	34	fusion	fusion	NN
cord-256444-grw5s2pf	725	35	of	of	IN
cord-256444-grw5s2pf	725	36	two	two	CD
cord-256444-grw5s2pf	725	37	discontiguous	discontiguous	JJ
cord-256444-grw5s2pf	725	38	sequences	sequence	NNS
cord-256444-grw5s2pf	725	39	either	either	CC
cord-256444-grw5s2pf	725	40	during	during	IN
cord-256444-grw5s2pf	725	41	or	or	CC
cord-256444-grw5s2pf	725	42	after	after	IN
cord-256444-grw5s2pf	725	43	transcription	transcription	NN
cord-256444-grw5s2pf	725	44	.	.	.
cord-256444-grw5s2pf	726	1	An	an	DT
cord-256444-grw5s2pf	726	2	early	early	JJ
cord-256444-grw5s2pf	726	3	study	study	NN
cord-256444-grw5s2pf	726	4	showed	show	VBD
cord-256444-grw5s2pf	726	5	that	that	IN
cord-256444-grw5s2pf	726	6	the	the	DT
cord-256444-grw5s2pf	726	7	leader	leader	NN
cord-256444-grw5s2pf	726	8	sequence	sequence	NN
cord-256444-grw5s2pf	726	9	of	of	IN
cord-256444-grw5s2pf	726	10	each	each	DT
cord-256444-grw5s2pf	726	11	mRNA	mrna	NN
cord-256444-grw5s2pf	726	12	can	can	MD
cord-256444-grw5s2pf	726	13	be	be	VB
cord-256444-grw5s2pf	726	14	exchanged	exchange	VBN
cord-256444-grw5s2pf	726	15	freely	freely	RB
cord-256444-grw5s2pf	726	16	between	between	IN
cord-256444-grw5s2pf	726	17	two	two	CD
cord-256444-grw5s2pf	726	18	coinfecting	coinfecte	VBG
cord-256444-grw5s2pf	726	19	viruses	virus	NNS
cord-256444-grw5s2pf	726	20	,	,	,
cord-256444-grw5s2pf	726	21	suggesting	suggest	VBG
cord-256444-grw5s2pf	726	22	that	that	IN
cord-256444-grw5s2pf	726	23	the	the	DT
cord-256444-grw5s2pf	726	24	leader	leader	NN
cord-256444-grw5s2pf	726	25	RNA	RNA	NNP
cord-256444-grw5s2pf	726	26	and	and	CC
cord-256444-grw5s2pf	726	27	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	726	28	are	be	VBP
cord-256444-grw5s2pf	726	29	transcribed	transcribe	VBN
cord-256444-grw5s2pf	726	30	independently	independently	RB
cord-256444-grw5s2pf	726	31	and	and	CC
cord-256444-grw5s2pf	726	32	can	can	MD
cord-256444-grw5s2pf	726	33	conjoin	conjoin	VB
cord-256444-grw5s2pf	726	34	in	in	IN
cord-256444-grw5s2pf	726	35	a	a	DT
cord-256444-grw5s2pf	726	36	random	random	JJ
cord-256444-grw5s2pf	726	37	fashion	fashion	NN
cord-256444-grw5s2pf	726	38	(	(	-LRB-
cord-256444-grw5s2pf	726	39	Makino	Makino	NNP
cord-256444-grw5s2pf	726	40	et	et	NNP
cord-256444-grw5s2pf	726	41	al	al	NNP
cord-256444-grw5s2pf	726	42	.	.	NNP
cord-256444-grw5s2pf	726	43	,	,	,
cord-256444-grw5s2pf	726	44	1986b	1986b	CD
cord-256444-grw5s2pf	726	45	)	)	-RRB-
cord-256444-grw5s2pf	726	46	.	.	.
cord-256444-grw5s2pf	727	1	More	More	JJR
cord-256444-grw5s2pf	727	2	recent	recent	JJ
cord-256444-grw5s2pf	727	3	studies	study	NNS
cord-256444-grw5s2pf	727	4	using	use	VBG
cord-256444-grw5s2pf	727	5	DI	DI	NNP
cord-256444-grw5s2pf	727	6	RNA	RNA	NNP
cord-256444-grw5s2pf	727	7	constructs	construct	NNS
cord-256444-grw5s2pf	727	8	that	that	WDT
cord-256444-grw5s2pf	727	9	contain	contain	VBP
cord-256444-grw5s2pf	727	10	an	an	DT
cord-256444-grw5s2pf	727	11	inserted	insert	VBN
cord-256444-grw5s2pf	727	12	mRNA	mrna	NN
cord-256444-grw5s2pf	727	13	start	start	NN
cord-256444-grw5s2pf	727	14	signal	signal	NN
cord-256444-grw5s2pf	727	15	(	(	-LRB-
cord-256444-grw5s2pf	727	16	see	see	VB
cord-256444-grw5s2pf	727	17	below	below	RB
cord-256444-grw5s2pf	727	18	)	)	-RRB-
cord-256444-grw5s2pf	727	19	established	establish	VBD
cord-256444-grw5s2pf	727	20	that	that	IN
cord-256444-grw5s2pf	727	21	the	the	DT
cord-256444-grw5s2pf	727	22	leader	leader	NN
cord-256444-grw5s2pf	727	23	RNA	RNA	NNP
cord-256444-grw5s2pf	727	24	and	and	CC
cord-256444-grw5s2pf	727	25	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	727	26	are	be	VBP
cord-256444-grw5s2pf	727	27	usually	usually	RB
cord-256444-grw5s2pf	727	28	derived	derive	VBN
cord-256444-grw5s2pf	727	29	from	from	IN
cord-256444-grw5s2pf	727	30	two	two	CD
cord-256444-grw5s2pf	727	31	separate	separate	JJ
cord-256444-grw5s2pf	727	32	RNA	rna	NN
cord-256444-grw5s2pf	727	33	molecules	molecule	NNS
cord-256444-grw5s2pf	727	34	(	(	-LRB-
cord-256444-grw5s2pf	727	35	Jeong	Jeong	NNP
cord-256444-grw5s2pf	727	36	and	and	CC
cord-256444-grw5s2pf	727	37	Makino	Makino	NNP
cord-256444-grw5s2pf	727	38	,	,	,
cord-256444-grw5s2pf	727	39	1994	1994	CD
cord-256444-grw5s2pf	727	40	;	;	:
cord-256444-grw5s2pf	727	41	Zhang	Zhang	NNP
cord-256444-grw5s2pf	727	42	et	et	NNP
cord-256444-grw5s2pf	727	43	al	al	NNP
cord-256444-grw5s2pf	727	44	.	.	NNP
cord-256444-grw5s2pf	727	45	,	,	,
cord-256444-grw5s2pf	727	46	1994b	1994b	CD
cord-256444-grw5s2pf	727	47	)	)	-RRB-
cord-256444-grw5s2pf	727	48	.	.	.
cord-256444-grw5s2pf	728	1	These	these	DT
cord-256444-grw5s2pf	728	2	studies	study	NNS
cord-256444-grw5s2pf	728	3	unequivocally	unequivocally	RB
cord-256444-grw5s2pf	728	4	showed	show	VBD
cord-256444-grw5s2pf	728	5	that	that	IN
cord-256444-grw5s2pf	728	6	coronaviral	coronaviral	NNP
cord-256444-grw5s2pf	728	7	mRNA	mRNA	NNP
cord-256444-grw5s2pf	728	8	synthesis	synthesis	NN
cord-256444-grw5s2pf	728	9	is	be	VBZ
cord-256444-grw5s2pf	728	10	carried	carry	VBN
cord-256444-grw5s2pf	728	11	out	out	RP
cord-256444-grw5s2pf	728	12	by	by	IN
cord-256444-grw5s2pf	728	13	either	either	CC
cord-256444-grw5s2pf	728	14	a	a	DT
cord-256444-grw5s2pf	728	15	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	728	16	transcription	transcription	NN
cord-256444-grw5s2pf	728	17	or	or	CC
cord-256444-grw5s2pf	728	18	transsplicing	transsplicing	NN
cord-256444-grw5s2pf	728	19	process	process	NN
cord-256444-grw5s2pf	728	20	,	,	,
cord-256444-grw5s2pf	728	21	which	which	WDT
cord-256444-grw5s2pf	728	22	fuses	fuse	VBZ
cord-256444-grw5s2pf	728	23	sequences	sequence	NNS
cord-256444-grw5s2pf	728	24	from	from	IN
cord-256444-grw5s2pf	728	25	two	two	CD
cord-256444-grw5s2pf	728	26	different	different	JJ
cord-256444-grw5s2pf	728	27	RNA	RNA	NNP
cord-256444-grw5s2pf	728	28	molecules	molecule	NNS
cord-256444-grw5s2pf	728	29	.	.	.
cord-256444-grw5s2pf	729	1	Several	several	JJ
cord-256444-grw5s2pf	729	2	transcription	transcription	NN
cord-256444-grw5s2pf	729	3	models	model	NNS
cord-256444-grw5s2pf	729	4	have	have	VBP
cord-256444-grw5s2pf	729	5	been	be	VBN
cord-256444-grw5s2pf	729	6	proposed	propose	VBN
cord-256444-grw5s2pf	729	7	,	,	,
cord-256444-grw5s2pf	729	8	each	each	DT
cord-256444-grw5s2pf	729	9	of	of	IN
cord-256444-grw5s2pf	729	10	which	which	WDT
cord-256444-grw5s2pf	729	11	is	be	VBZ
cord-256444-grw5s2pf	729	12	consistent	consistent	JJ
cord-256444-grw5s2pf	729	13	with	with	IN
cord-256444-grw5s2pf	729	14	some	some	DT
cord-256444-grw5s2pf	729	15	of	of	IN
cord-256444-grw5s2pf	729	16	the	the	DT
cord-256444-grw5s2pf	729	17	experimental	experimental	JJ
cord-256444-grw5s2pf	729	18	data	datum	NNS
cord-256444-grw5s2pf	729	19	.	.	.
cord-256444-grw5s2pf	730	1	These	these	DT
cord-256444-grw5s2pf	730	2	models	model	NNS
cord-256444-grw5s2pf	730	3	are	be	VBP
cord-256444-grw5s2pf	730	4	not	not	RB
cord-256444-grw5s2pf	730	5	mutually	mutually	RB
cord-256444-grw5s2pf	730	6	exclusive	exclusive	JJ
cord-256444-grw5s2pf	730	7	,	,	,
cord-256444-grw5s2pf	730	8	as	as	IN
cord-256444-grw5s2pf	730	9	components	component	NNS
cord-256444-grw5s2pf	730	10	of	of	IN
cord-256444-grw5s2pf	730	11	each	each	DT
cord-256444-grw5s2pf	730	12	model	model	NN
cord-256444-grw5s2pf	730	13	may	may	MD
cord-256444-grw5s2pf	730	14	operate	operate	VB
cord-256444-grw5s2pf	730	15	at	at	IN
cord-256444-grw5s2pf	730	16	different	different	JJ
cord-256444-grw5s2pf	730	17	stages	stage	NNS
cord-256444-grw5s2pf	730	18	of	of	IN
cord-256444-grw5s2pf	730	19	the	the	DT
cord-256444-grw5s2pf	730	20	viral	viral	JJ
cord-256444-grw5s2pf	730	21	replication	replication	NN
cord-256444-grw5s2pf	730	22	cycle	cycle	NN
cord-256444-grw5s2pf	730	23	.	.	.
cord-256444-grw5s2pf	731	1	Before	before	IN
cord-256444-grw5s2pf	731	2	presenting	present	VBG
cord-256444-grw5s2pf	731	3	these	these	DT
cord-256444-grw5s2pf	731	4	models	model	NNS
cord-256444-grw5s2pf	731	5	,	,	,
cord-256444-grw5s2pf	731	6	we	-PRON-	PRP
cord-256444-grw5s2pf	731	7	will	will	MD
cord-256444-grw5s2pf	731	8	discuss	discuss	VB
cord-256444-grw5s2pf	731	9	several	several	JJ
cord-256444-grw5s2pf	731	10	findings	finding	NNS
cord-256444-grw5s2pf	731	11	pertinent	pertinent	JJ
cord-256444-grw5s2pf	731	12	to	to	IN
cord-256444-grw5s2pf	731	13	coronaviral	coronaviral	NNP
cord-256444-grw5s2pf	731	14	RNA	RNA	NNP
cord-256444-grw5s2pf	731	15	transcription	transcription	NN
cord-256444-grw5s2pf	731	16	.	.	.
cord-256444-grw5s2pf	732	1	1	1	LS
cord-256444-grw5s2pf	732	2	.	.	.
cord-256444-grw5s2pf	733	1	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	733	2	replication	replication	NN
cord-256444-grw5s2pf	733	3	takes	take	VBZ
cord-256444-grw5s2pf	733	4	place	place	NN
cord-256444-grw5s2pf	733	5	entirely	entirely	RB
cord-256444-grw5s2pf	733	6	in	in	IN
cord-256444-grw5s2pf	733	7	the	the	DT
cord-256444-grw5s2pf	733	8	cytoplasm	cytoplasm	NN
cord-256444-grw5s2pf	733	9	.	.	.
cord-256444-grw5s2pf	734	1	Nuclear	nuclear	JJ
cord-256444-grw5s2pf	734	2	functions	function	NNS
cord-256444-grw5s2pf	734	3	are	be	VBP
cord-256444-grw5s2pf	734	4	believed	believe	VBN
cord-256444-grw5s2pf	734	5	not	not	RB
cord-256444-grw5s2pf	734	6	to	to	TO
cord-256444-grw5s2pf	734	7	be	be	VB
cord-256444-grw5s2pf	734	8	required	require	VBN
cord-256444-grw5s2pf	734	9	for	for	IN
cord-256444-grw5s2pf	734	10	RNA	RNA	NNP
cord-256444-grw5s2pf	734	11	synthesis	synthesis	NN
cord-256444-grw5s2pf	735	1	Wilhelmsen	Wilhelmsen	NNP
cord-256444-grw5s2pf	735	2	et	et	NNP
cord-256444-grw5s2pf	735	3	al	al	NNP
cord-256444-grw5s2pf	735	4	.	.	NNP
cord-256444-grw5s2pf	735	5	,	,	,
cord-256444-grw5s2pf	735	6	1981	1981	CD
cord-256444-grw5s2pf	735	7	)	)	-RRB-
cord-256444-grw5s2pf	735	8	;	;	:
cord-256444-grw5s2pf	735	9	thus	thus	RB
cord-256444-grw5s2pf	735	10	,	,	,
cord-256444-grw5s2pf	735	11	viral	viral	JJ
cord-256444-grw5s2pf	735	12	RNA	RNA	NNP
cord-256444-grw5s2pf	735	13	transcription	transcription	NN
cord-256444-grw5s2pf	735	14	does	do	VBZ
cord-256444-grw5s2pf	735	15	not	not	RB
cord-256444-grw5s2pf	735	16	involve	involve	VB
cord-256444-grw5s2pf	735	17	the	the	DT
cord-256444-grw5s2pf	735	18	conventional	conventional	JJ
cord-256444-grw5s2pf	735	19	RNA	RNA	NNP
cord-256444-grw5s2pf	735	20	splicing	splicing	NN
cord-256444-grw5s2pf	735	21	machinery	machinery	NN
cord-256444-grw5s2pf	735	22	present	present	JJ
cord-256444-grw5s2pf	735	23	in	in	IN
cord-256444-grw5s2pf	735	24	the	the	DT
cord-256444-grw5s2pf	735	25	nucleus	nucleus	NN
cord-256444-grw5s2pf	735	26	.	.	.
cord-256444-grw5s2pf	736	1	2	2	LS
cord-256444-grw5s2pf	736	2	.	.	.
cord-256444-grw5s2pf	737	1	Early	early	JJ
cord-256444-grw5s2pf	737	2	ultraviolet	ultraviolet	NN
cord-256444-grw5s2pf	737	3	(	(	-LRB-
cord-256444-grw5s2pf	737	4	W	w	NN
cord-256444-grw5s2pf	737	5	)	)	-RRB-
cord-256444-grw5s2pf	737	6	transcriptional	transcriptional	JJ
cord-256444-grw5s2pf	737	7	mapping	mapping	NN
cord-256444-grw5s2pf	737	8	studies	study	NNS
cord-256444-grw5s2pf	737	9	indicated	indicate	VBD
cord-256444-grw5s2pf	737	10	that	that	IN
cord-256444-grw5s2pf	737	11	in	in	IN
cord-256444-grw5s2pf	737	12	the	the	DT
cord-256444-grw5s2pf	737	13	late	late	JJ
cord-256444-grw5s2pf	737	14	stage	stage	NN
cord-256444-grw5s2pf	737	15	of	of	IN
cord-256444-grw5s2pf	737	16	viral	viral	JJ
cord-256444-grw5s2pf	737	17	replication	replication	NN
cord-256444-grw5s2pf	737	18	,	,	,
cord-256444-grw5s2pf	737	19	the	the	DT
cord-256444-grw5s2pf	737	20	W	w	NN
cord-256444-grw5s2pf	737	21	target	target	NN
cord-256444-grw5s2pf	737	22	size	size	NN
cord-256444-grw5s2pf	737	23	of	of	IN
cord-256444-grw5s2pf	737	24	each	each	DT
cord-256444-grw5s2pf	737	25	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	737	26	and	and	CC
cord-256444-grw5s2pf	737	27	genomic	genomic	JJ
cord-256444-grw5s2pf	737	28	mRNA	mRNA	NNP
cord-256444-grw5s2pf	737	29	is	be	VBZ
cord-256444-grw5s2pf	737	30	approximately	approximately	RB
cord-256444-grw5s2pf	737	31	equivalent	equivalent	JJ
cord-256444-grw5s2pf	737	32	to	to	IN
cord-256444-grw5s2pf	737	33	the	the	DT
cord-256444-grw5s2pf	737	34	physical	physical	JJ
cord-256444-grw5s2pf	737	35	size	size	NN
cord-256444-grw5s2pf	737	36	of	of	IN
cord-256444-grw5s2pf	737	37	the	the	DT
cord-256444-grw5s2pf	737	38	respective	respective	JJ
cord-256444-grw5s2pf	737	39	mRNA	mrna	NN
cord-256444-grw5s2pf	738	1	(	(	-LRB-
cord-256444-grw5s2pf	738	2	Jacobs	Jacobs	NNP
cord-256444-grw5s2pf	738	3	et	et	NNP
cord-256444-grw5s2pf	738	4	al	al	NNP
cord-256444-grw5s2pf	738	5	.	.	NNP
cord-256444-grw5s2pf	738	6	,	,	,
cord-256444-grw5s2pf	738	7	1981	1981	CD
cord-256444-grw5s2pf	738	8	;	;	:
cord-256444-grw5s2pf	738	9	Stern	Stern	NNP
cord-256444-grw5s2pf	738	10	and	and	CC
cord-256444-grw5s2pf	738	11	Sefton	Sefton	NNP
cord-256444-grw5s2pf	738	12	,	,	,
cord-256444-grw5s2pf	738	13	1982a	1982a	CD
cord-256444-grw5s2pf	738	14	)	)	-RRB-
cord-256444-grw5s2pf	738	15	;	;	:
cord-256444-grw5s2pf	738	16	thus	thus	RB
cord-256444-grw5s2pf	738	17	,	,	,
cord-256444-grw5s2pf	738	18	each	each	DT
cord-256444-grw5s2pf	738	19	mRNA	mrna	NN
cord-256444-grw5s2pf	738	20	is	be	VBZ
cord-256444-grw5s2pf	738	21	transcribed	transcribe	VBN
cord-256444-grw5s2pf	738	22	independently	independently	RB
cord-256444-grw5s2pf	738	23	rather	rather	RB
cord-256444-grw5s2pf	738	24	than	than	IN
cord-256444-grw5s2pf	738	25	derived	derive	VBN
cord-256444-grw5s2pf	738	26	by	by	IN
cord-256444-grw5s2pf	738	27	the	the	DT
cord-256444-grw5s2pf	738	28	processing	processing	NN
cord-256444-grw5s2pf	738	29	of	of	IN
cord-256444-grw5s2pf	738	30	a	a	DT
cord-256444-grw5s2pf	738	31	large	large	JJ
cord-256444-grw5s2pf	738	32	precursor	precursor	NN
cord-256444-grw5s2pf	738	33	RNA	rna	NN
cord-256444-grw5s2pf	738	34	.	.	.
cord-256444-grw5s2pf	739	1	However	however	RB
cord-256444-grw5s2pf	739	2	,	,	,
cord-256444-grw5s2pf	739	3	early	early	RB
cord-256444-grw5s2pf	739	4	in	in	IN
cord-256444-grw5s2pf	739	5	infection	infection	NN
cord-256444-grw5s2pf	739	6	,	,	,
cord-256444-grw5s2pf	739	7	the	the	DT
cord-256444-grw5s2pf	739	8	W	w	NN
cord-256444-grw5s2pf	739	9	target	target	NN
cord-256444-grw5s2pf	739	10	sizes	size	NNS
cord-256444-grw5s2pf	739	11	of	of	IN
cord-256444-grw5s2pf	739	12	the	the	DT
cord-256444-grw5s2pf	739	13	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	739	14	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	739	15	were	be	VBD
cord-256444-grw5s2pf	739	16	found	find	VBN
cord-256444-grw5s2pf	739	17	to	to	TO
cord-256444-grw5s2pf	739	18	be	be	VB
cord-256444-grw5s2pf	739	19	equivalent	equivalent	JJ
cord-256444-grw5s2pf	739	20	to	to	IN
cord-256444-grw5s2pf	739	21	that	that	DT
cord-256444-grw5s2pf	739	22	of	of	IN
cord-256444-grw5s2pf	739	23	the	the	DT
cord-256444-grw5s2pf	739	24	genomic	genomic	JJ
cord-256444-grw5s2pf	739	25	RNA	RNA	NNP
cord-256444-grw5s2pf	739	26	(	(	-LRB-
cord-256444-grw5s2pf	739	27	Yokomori	Yokomori	NNP
cord-256444-grw5s2pf	739	28	et	et	FW
cord-256444-grw5s2pf	739	29	al	al	NNP
cord-256444-grw5s2pf	739	30	.	.	NNP
cord-256444-grw5s2pf	739	31	,	,	,
cord-256444-grw5s2pf	739	32	199213	199213	CD
cord-256444-grw5s2pf	739	33	)	)	-RRB-
cord-256444-grw5s2pf	739	34	;	;	:
cord-256444-grw5s2pf	739	35	thus	thus	RB
cord-256444-grw5s2pf	739	36	,	,	,
cord-256444-grw5s2pf	739	37	at	at	IN
cord-256444-grw5s2pf	739	38	least	least	JJS
cord-256444-grw5s2pf	739	39	early	early	RB
cord-256444-grw5s2pf	739	40	in	in	IN
cord-256444-grw5s2pf	739	41	infection	infection	NN
cord-256444-grw5s2pf	739	42	,	,	,
cord-256444-grw5s2pf	739	43	the	the	DT
cord-256444-grw5s2pf	739	44	synthesis	synthesis	NN
cord-256444-grw5s2pf	739	45	of	of	IN
cord-256444-grw5s2pf	739	46	a	a	DT
cord-256444-grw5s2pf	739	47	genomic	genomic	JJ
cord-256444-grw5s2pf	739	48	-	-	HYPH
cord-256444-grw5s2pf	739	49	length	length	NN
cord-256444-grw5s2pf	739	50	RNA	RNA	NNP
cord-256444-grw5s2pf	739	51	is	be	VBZ
cord-256444-grw5s2pf	739	52	required	require	VBN
cord-256444-grw5s2pf	739	53	for	for	IN
cord-256444-grw5s2pf	739	54	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	739	55	mRNA	mRNA	NNP
cord-256444-grw5s2pf	739	56	synthesis	synthesis	NNP
cord-256444-grw5s2pf	739	57	,	,	,
cord-256444-grw5s2pf	739	58	although	although	IN
cord-256444-grw5s2pf	739	59	it	-PRON-	PRP
cord-256444-grw5s2pf	739	60	is	be	VBZ
cord-256444-grw5s2pf	739	61	not	not	RB
cord-256444-grw5s2pf	739	62	clear	clear	JJ
cord-256444-grw5s2pf	739	63	whether	whether	IN
cord-256444-grw5s2pf	739	64	this	this	DT
cord-256444-grw5s2pf	739	65	requirement	requirement	NN
cord-256444-grw5s2pf	739	66	is	be	VBZ
cord-256444-grw5s2pf	739	67	for	for	IN
cord-256444-grw5s2pf	739	68	a	a	DT
cord-256444-grw5s2pf	739	69	positive	positive	JJ
cord-256444-grw5s2pf	739	70	-	-	:
cord-256444-grw5s2pf	739	71	or	or	CC
cord-256444-grw5s2pf	739	72	a	a	DT
cord-256444-grw5s2pf	739	73	negative	negative	NN
cord-256444-grw5s2pf	739	74	-	-	HYPH
cord-256444-grw5s2pf	739	75	stranded	stranded	JJ
cord-256444-grw5s2pf	739	76	,	,	,
cord-256444-grw5s2pf	739	77	full	full	JJ
cord-256444-grw5s2pf	739	78	-	-	HYPH
cord-256444-grw5s2pf	739	79	length	length	NN
cord-256444-grw5s2pf	739	80	RNA	RNA	NNP
cord-256444-grw5s2pf	739	81	.	.	.
cord-256444-grw5s2pf	740	1	A	a	DT
cord-256444-grw5s2pf	740	2	more	more	RBR
cord-256444-grw5s2pf	740	3	recent	recent	JJ
cord-256444-grw5s2pf	740	4	analysis	analysis	NN
cord-256444-grw5s2pf	740	5	of	of	IN
cord-256444-grw5s2pf	740	6	the	the	DT
cord-256444-grw5s2pf	740	7	UV	uv	NN
cord-256444-grw5s2pf	740	8	target	target	NN
cord-256444-grw5s2pf	740	9	sizes	size	NNS
cord-256444-grw5s2pf	740	10	of	of	IN
cord-256444-grw5s2pf	740	11	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	740	12	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	740	13	of	of	IN
cord-256444-grw5s2pf	740	14	MHV	MHV	NNP
cord-256444-grw5s2pf	740	15	suggested	suggest	VBD
cord-256444-grw5s2pf	740	16	that	that	IN
cord-256444-grw5s2pf	740	17	,	,	,
cord-256444-grw5s2pf	740	18	even	even	RB
cord-256444-grw5s2pf	740	19	late	late	RB
cord-256444-grw5s2pf	740	20	in	in	IN
cord-256444-grw5s2pf	740	21	the	the	DT
cord-256444-grw5s2pf	740	22	infection	infection	NN
cord-256444-grw5s2pf	740	23	,	,	,
cord-256444-grw5s2pf	740	24	the	the	DT
cord-256444-grw5s2pf	740	25	W	w	NN
cord-256444-grw5s2pf	740	26	target	target	NN
cord-256444-grw5s2pf	740	27	sizes	size	NNS
cord-256444-grw5s2pf	740	28	of	of	IN
cord-256444-grw5s2pf	740	29	some	some	DT
cord-256444-grw5s2pf	740	30	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	740	31	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	740	32	are	be	VBP
cord-256444-grw5s2pf	740	33	slightly	slightly	RB
cord-256444-grw5s2pf	740	34	larger	large	JJR
cord-256444-grw5s2pf	740	35	than	than	IN
cord-256444-grw5s2pf	740	36	their	-PRON-	PRP$
cord-256444-grw5s2pf	740	37	physical	physical	JJ
cord-256444-grw5s2pf	740	38	lengths	length	NNS
cord-256444-grw5s2pf	740	39	but	but	CC
cord-256444-grw5s2pf	740	40	smaller	small	JJR
cord-256444-grw5s2pf	740	41	than	than	IN
cord-256444-grw5s2pf	740	42	genomic	genomic	JJ
cord-256444-grw5s2pf	740	43	size	size	NN
cord-256444-grw5s2pf	740	44	(	(	-LRB-
cord-256444-grw5s2pf	740	45	den	den	NNP
cord-256444-grw5s2pf	740	46	Boon	Boon	NNP
cord-256444-grw5s2pf	740	47	et	et	NNP
cord-256444-grw5s2pf	740	48	al	al	NNP
cord-256444-grw5s2pf	740	49	.	.	NNP
cord-256444-grw5s2pf	740	50	,	,	,
cord-256444-grw5s2pf	740	51	1995	1995	CD
cord-256444-grw5s2pf	740	52	)	)	-RRB-
cord-256444-grw5s2pf	740	53	.	.	.
cord-256444-grw5s2pf	741	1	Similar	similar	JJ
cord-256444-grw5s2pf	741	2	observations	observation	NNS
cord-256444-grw5s2pf	741	3	were	be	VBD
cord-256444-grw5s2pf	741	4	made	make	VBN
cord-256444-grw5s2pf	741	5	for	for	IN
cord-256444-grw5s2pf	741	6	equine	equine	JJ
cord-256444-grw5s2pf	741	7	arteritis	arteritis	NN
cord-256444-grw5s2pf	741	8	virus	virus	NN
cord-256444-grw5s2pf	741	9	(	(	-LRB-
cord-256444-grw5s2pf	741	10	an	an	DT
cord-256444-grw5s2pf	741	11	arterivirus	arterivirus	NN
cord-256444-grw5s2pf	741	12	)	)	-RRB-
cord-256444-grw5s2pf	741	13	.	.	.
cord-256444-grw5s2pf	742	1	This	this	DT
cord-256444-grw5s2pf	742	2	recent	recent	JJ
cord-256444-grw5s2pf	742	3	result	result	NN
cord-256444-grw5s2pf	742	4	is	be	VBZ
cord-256444-grw5s2pf	742	5	consistent	consistent	JJ
cord-256444-grw5s2pf	742	6	with	with	IN
cord-256444-grw5s2pf	742	7	either	either	DT
cord-256444-grw5s2pf	742	8	of	of	IN
cord-256444-grw5s2pf	742	9	two	two	CD
cord-256444-grw5s2pf	742	10	interpretations	interpretation	NNS
cord-256444-grw5s2pf	742	11	:	:	:
cord-256444-grw5s2pf	742	12	(	(	-LRB-
cord-256444-grw5s2pf	742	13	a	a	LS
cord-256444-grw5s2pf	742	14	)	)	-RRB-
cord-256444-grw5s2pf	743	1	the	the	DT
cord-256444-grw5s2pf	743	2	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	743	3	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	743	4	are	be	VBP
cord-256444-grw5s2pf	743	5	derived	derive	VBN
cord-256444-grw5s2pf	743	6	from	from	IN
cord-256444-grw5s2pf	743	7	a	a	DT
cord-256444-grw5s2pf	743	8	slightly	slightly	RB
cord-256444-grw5s2pf	743	9	longer	long	JJR
cord-256444-grw5s2pf	743	10	RNA	rna	NN
cord-256444-grw5s2pf	743	11	template	template	NN
cord-256444-grw5s2pf	743	12	or	or	CC
cord-256444-grw5s2pf	743	13	(	(	-LRB-
cord-256444-grw5s2pf	743	14	b	b	LS
cord-256444-grw5s2pf	743	15	)	)	-RRB-
cord-256444-grw5s2pf	743	16	they	-PRON-	PRP
cord-256444-grw5s2pf	743	17	are	be	VBP
cord-256444-grw5s2pf	743	18	derived	derive	VBN
cord-256444-grw5s2pf	743	19	from	from	IN
cord-256444-grw5s2pf	743	20	a	a	DT
cord-256444-grw5s2pf	743	21	mixture	mixture	NN
cord-256444-grw5s2pf	743	22	of	of	IN
cord-256444-grw5s2pf	743	23	templates	template	NNS
cord-256444-grw5s2pf	743	24	of	of	IN
cord-256444-grw5s2pf	743	25	different	different	JJ
cord-256444-grw5s2pf	743	26	sizes	size	NNS
cord-256444-grw5s2pf	743	27	(	(	-LRB-
cord-256444-grw5s2pf	743	28	genomic	genomic	JJ
cord-256444-grw5s2pf	743	29	as	as	RB
cord-256444-grw5s2pf	743	30	well	well	RB
cord-256444-grw5s2pf	743	31	as	as	IN
cord-256444-grw5s2pf	743	32	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	743	33	)	)	-RRB-
cord-256444-grw5s2pf	743	34	.	.	.
cord-256444-grw5s2pf	744	1	The	the	DT
cord-256444-grw5s2pf	744	2	difference	difference	NN
cord-256444-grw5s2pf	744	3	in	in	IN
cord-256444-grw5s2pf	744	4	W	w	NN
cord-256444-grw5s2pf	744	5	target	target	NN
cord-256444-grw5s2pf	744	6	size	size	NN
cord-256444-grw5s2pf	744	7	between	between	IN
cord-256444-grw5s2pf	744	8	the	the	DT
cord-256444-grw5s2pf	744	9	early	early	JJ
cord-256444-grw5s2pf	744	10	and	and	CC
cord-256444-grw5s2pf	744	11	late	late	JJ
cord-256444-grw5s2pf	744	12	stages	stage	NNS
cord-256444-grw5s2pf	744	13	of	of	IN
cord-256444-grw5s2pf	744	14	viral	viral	JJ
cord-256444-grw5s2pf	744	15	RNA	RNA	NNP
cord-256444-grw5s2pf	744	16	replication	replication	NN
cord-256444-grw5s2pf	744	17	suggests	suggest	VBZ
cord-256444-grw5s2pf	744	18	that	that	IN
cord-256444-grw5s2pf	744	19	different	different	JJ
cord-256444-grw5s2pf	744	20	mechanisms	mechanism	NNS
cord-256444-grw5s2pf	744	21	of	of	IN
cord-256444-grw5s2pf	744	22	RNA	RNA	NNP
cord-256444-grw5s2pf	744	23	synthesis	synthesis	NN
cord-256444-grw5s2pf	744	24	may	may	MD
cord-256444-grw5s2pf	744	25	operate	operate	VB
cord-256444-grw5s2pf	744	26	at	at	IN
cord-256444-grw5s2pf	744	27	the	the	DT
cord-256444-grw5s2pf	744	28	different	different	JJ
cord-256444-grw5s2pf	744	29	stages	stage	NNS
cord-256444-grw5s2pf	744	30	of	of	IN
cord-256444-grw5s2pf	744	31	the	the	DT
cord-256444-grw5s2pf	744	32	viral	viral	JJ
cord-256444-grw5s2pf	744	33	replication	replication	NN
cord-256444-grw5s2pf	744	34	cycle	cycle	NN
cord-256444-grw5s2pf	744	35	.	.	.
cord-256444-grw5s2pf	745	1	3	3	LS
cord-256444-grw5s2pf	745	2	.	.	.
cord-256444-grw5s2pf	746	1	The	the	DT
cord-256444-grw5s2pf	746	2	molar	molar	JJ
cord-256444-grw5s2pf	746	3	ratios	ratio	NNS
cord-256444-grw5s2pf	746	4	of	of	IN
cord-256444-grw5s2pf	746	5	different	different	JJ
cord-256444-grw5s2pf	746	6	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	746	7	mRNA	mRNA	NNP
cord-256444-grw5s2pf	746	8	species	specie	NNS
cord-256444-grw5s2pf	746	9	and	and	CC
cord-256444-grw5s2pf	746	10	those	those	DT
cord-256444-grw5s2pf	746	11	of	of	IN
cord-256444-grw5s2pf	746	12	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	746	13	negative	negative	JJ
cord-256444-grw5s2pf	746	14	-	-	HYPH
cord-256444-grw5s2pf	746	15	strand	strand	NN
cord-256444-grw5s2pf	746	16	RNAs	rna	NNS
cord-256444-grw5s2pf	746	17	are	be	VBP
cord-256444-grw5s2pf	746	18	similar	similar	JJ
cord-256444-grw5s2pf	746	19	(	(	-LRB-
cord-256444-grw5s2pf	746	20	Sethna	Sethna	NNP
cord-256444-grw5s2pf	746	21	et	et	NNP
cord-256444-grw5s2pf	746	22	al	al	NNP
cord-256444-grw5s2pf	746	23	.	.	NNP
cord-256444-grw5s2pf	746	24	,	,	,
cord-256444-grw5s2pf	746	25	1989	1989	CD
cord-256444-grw5s2pf	746	26	;	;	:
cord-256444-grw5s2pf	747	1	Hofmann	Hofmann	NNP
cord-256444-grw5s2pf	747	2	et	et	NNP
cord-256444-grw5s2pf	747	3	al	al	NNP
cord-256444-grw5s2pf	747	4	.	.	NNP
cord-256444-grw5s2pf	747	5	,	,	,
cord-256444-grw5s2pf	747	6	1990	1990	CD
cord-256444-grw5s2pf	747	7	)	)	-RRB-
cord-256444-grw5s2pf	747	8	,	,	,
cord-256444-grw5s2pf	747	9	suggesting	suggest	VBG
cord-256444-grw5s2pf	747	10	that	that	IN
cord-256444-grw5s2pf	747	11	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	747	12	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	747	13	and	and	CC
cord-256444-grw5s2pf	747	14	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	747	15	negative	negative	JJ
cord-256444-grw5s2pf	747	16	-	-	HYPH
cord-256444-grw5s2pf	747	17	strand	strand	NN
cord-256444-grw5s2pf	747	18	RNAs	rna	NNS
cord-256444-grw5s2pf	747	19	are	be	VBP
cord-256444-grw5s2pf	747	20	derived	derive	VBN
cord-256444-grw5s2pf	747	21	from	from	IN
cord-256444-grw5s2pf	747	22	each	each	DT
cord-256444-grw5s2pf	747	23	other	other	JJ
cord-256444-grw5s2pf	747	24	or	or	CC
cord-256444-grw5s2pf	747	25	under	under	IN
cord-256444-grw5s2pf	747	26	the	the	DT
cord-256444-grw5s2pf	747	27	same	same	JJ
cord-256444-grw5s2pf	747	28	transcriptional	transcriptional	JJ
cord-256444-grw5s2pf	747	29	regulation	regulation	NN
cord-256444-grw5s2pf	747	30	.	.	.
cord-256444-grw5s2pf	748	1	4	4	LS
cord-256444-grw5s2pf	748	2	.	.	.
cord-256444-grw5s2pf	749	1	The	the	DT
cord-256444-grw5s2pf	749	2	leader	leader	NN
cord-256444-grw5s2pf	749	3	RNA	RNA	NNP
cord-256444-grw5s2pf	749	4	at	at	IN
cord-256444-grw5s2pf	749	5	the	the	DT
cord-256444-grw5s2pf	749	6	5	5	CD
cord-256444-grw5s2pf	749	7	'	'	NN
cord-256444-grw5s2pf	749	8	end	end	NN
cord-256444-grw5s2pf	749	9	of	of	IN
cord-256444-grw5s2pf	749	10	each	each	DT
cord-256444-grw5s2pf	749	11	mRNA	mrna	NN
cord-256444-grw5s2pf	749	12	is	be	VBZ
cord-256444-grw5s2pf	749	13	identical	identical	JJ
cord-256444-grw5s2pf	749	14	in	in	IN
cord-256444-grw5s2pf	749	15	each	each	DT
cord-256444-grw5s2pf	749	16	mRNA	mrna	NN
cord-256444-grw5s2pf	749	17	and	and	CC
cord-256444-grw5s2pf	749	18	to	to	IN
cord-256444-grw5s2pf	749	19	the	the	DT
cord-256444-grw5s2pf	749	20	leader	leader	NN
cord-256444-grw5s2pf	749	21	RNA	RNA	NNP
cord-256444-grw5s2pf	749	22	at	at	IN
cord-256444-grw5s2pf	749	23	the	the	DT
cord-256444-grw5s2pf	749	24	5	5	CD
cord-256444-grw5s2pf	749	25	'	'	NN
cord-256444-grw5s2pf	749	26	end	end	NN
cord-256444-grw5s2pf	749	27	of	of	IN
cord-256444-grw5s2pf	749	28	genomic	genomic	JJ
cord-256444-grw5s2pf	749	29	RNA	rna	NN
cord-256444-grw5s2pf	749	30	.	.	.
cord-256444-grw5s2pf	750	1	Furthermore	furthermore	RB
cord-256444-grw5s2pf	750	2	,	,	,
cord-256444-grw5s2pf	750	3	there	there	EX
cord-256444-grw5s2pf	750	4	is	be	VBZ
cord-256444-grw5s2pf	750	5	sequence	sequence	NN
cord-256444-grw5s2pf	750	6	homology	homology	NN
cord-256444-grw5s2pf	750	7	between	between	IN
cord-256444-grw5s2pf	750	8	the	the	DT
cord-256444-grw5s2pf	750	9	3	3	CD
cord-256444-grw5s2pf	750	10	'	'	NN
cord-256444-grw5s2pf	750	11	end	end	NN
cord-256444-grw5s2pf	750	12	of	of	IN
cord-256444-grw5s2pf	750	13	the	the	DT
cord-256444-grw5s2pf	750	14	leader	leader	NN
cord-256444-grw5s2pf	750	15	RNA	RNA	NNP
cord-256444-grw5s2pf	750	16	and	and	CC
cord-256444-grw5s2pf	750	17	the	the	DT
cord-256444-grw5s2pf	750	18	mRNA	mRNA	NNP
cord-256444-grw5s2pf	751	1	start	start	VB
cord-256444-grw5s2pf	751	2	sites	site	NNS
cord-256444-grw5s2pf	751	3	on	on	IN
cord-256444-grw5s2pf	751	4	the	the	DT
cord-256444-grw5s2pf	751	5	genomic	genomic	JJ
cord-256444-grw5s2pf	751	6	RNA	RNA	NNP
cord-256444-grw5s2pf	751	7	(	(	-LRB-
cord-256444-grw5s2pf	751	8	Budzilowicz	Budzilowicz	NNP
cord-256444-grw5s2pf	751	9	et	et	NNP
cord-256444-grw5s2pf	751	10	al	al	NNP
cord-256444-grw5s2pf	751	11	.	.	NNP
cord-256444-grw5s2pf	751	12	,	,	,
cord-256444-grw5s2pf	751	13	1983	1983	CD
cord-256444-grw5s2pf	751	14	,	,	,
cord-256444-grw5s2pf	751	15	where	where	WRB
cord-256444-grw5s2pf	751	16	the	the	DT
cord-256444-grw5s2pf	751	17	leader	leader	NN
cord-256444-grw5s2pf	751	18	sequence	sequence	NN
cord-256444-grw5s2pf	751	19	is	be	VBZ
cord-256444-grw5s2pf	751	20	fused	fuse	VBN
cord-256444-grw5s2pf	751	21	to	to	IN
cord-256444-grw5s2pf	751	22	the	the	DT
cord-256444-grw5s2pf	751	23	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	751	24	.	.	.
cord-256444-grw5s2pf	752	1	There	there	EX
cord-256444-grw5s2pf	752	2	is	be	VBZ
cord-256444-grw5s2pf	752	3	some	some	DT
cord-256444-grw5s2pf	752	4	sequence	sequence	NN
cord-256444-grw5s2pf	752	5	divergence	divergence	NN
cord-256444-grw5s2pf	752	6	between	between	IN
cord-256444-grw5s2pf	752	7	the	the	DT
cord-256444-grw5s2pf	752	8	leader	leader	NN
cord-256444-grw5s2pf	752	9	RNA	RNA	NNP
cord-256444-grw5s2pf	752	10	and	and	CC
cord-256444-grw5s2pf	752	11	some	some	DT
cord-256444-grw5s2pf	752	12	of	of	IN
cord-256444-grw5s2pf	752	13	the	the	DT
cord-256444-grw5s2pf	752	14	mRNA	mRNA	NNP
cord-256444-grw5s2pf	752	15	start	start	VB
cord-256444-grw5s2pf	752	16	sites	site	NNS
cord-256444-grw5s2pf	752	17	;	;	:
cord-256444-grw5s2pf	752	18	in	in	IN
cord-256444-grw5s2pf	752	19	these	these	DT
cord-256444-grw5s2pf	752	20	cases	case	NNS
cord-256444-grw5s2pf	752	21	,	,	,
cord-256444-grw5s2pf	752	22	the	the	DT
cord-256444-grw5s2pf	752	23	leader	leader	NN
cord-256444-grw5s2pf	752	24	RNA	RNA	NNP
cord-256444-grw5s2pf	752	25	of	of	IN
cord-256444-grw5s2pf	752	26	the	the	DT
cord-256444-grw5s2pf	752	27	resulting	resulting	NN
cord-256444-grw5s2pf	752	28	mRNAs	mRNAs	-RRB-
cord-256444-grw5s2pf	752	29	usually	usually	RB
cord-256444-grw5s2pf	752	30	mimics	mimic	VBZ
cord-256444-grw5s2pf	752	31	the	the	DT
cord-256444-grw5s2pf	752	32	sequence	sequence	NN
cord-256444-grw5s2pf	752	33	of	of	IN
cord-256444-grw5s2pf	752	34	the	the	DT
cord-256444-grw5s2pf	752	35	mRNA	mRNA	NNP
cord-256444-grw5s2pf	752	36	start	start	NN
cord-256444-grw5s2pf	752	37	site	site	NN
cord-256444-grw5s2pf	752	38	rather	rather	RB
cord-256444-grw5s2pf	752	39	than	than	IN
cord-256444-grw5s2pf	752	40	the	the	DT
cord-256444-grw5s2pf	752	41	leader	leader	NN
cord-256444-grw5s2pf	752	42	at	at	IN
cord-256444-grw5s2pf	752	43	the	the	DT
cord-256444-grw5s2pf	752	44	5	5	CD
cord-256444-grw5s2pf	752	45	'	'	NN
cord-256444-grw5s2pf	752	46	end	end	NN
cord-256444-grw5s2pf	752	47	of	of	IN
cord-256444-grw5s2pf	752	48	the	the	DT
cord-256444-grw5s2pf	752	49	genome	genome	NN
cord-256444-grw5s2pf	752	50	.	.	.
cord-256444-grw5s2pf	753	1	This	this	DT
cord-256444-grw5s2pf	753	2	finding	finding	NN
cord-256444-grw5s2pf	753	3	was	be	VBD
cord-256444-grw5s2pf	753	4	used	use	VBN
cord-256444-grw5s2pf	753	5	to	to	TO
cord-256444-grw5s2pf	753	6	suggest	suggest	VB
cord-256444-grw5s2pf	753	7	the	the	DT
cord-256444-grw5s2pf	753	8	possible	possible	JJ
cord-256444-grw5s2pf	753	9	presence	presence	NN
cord-256444-grw5s2pf	753	10	of	of	IN
cord-256444-grw5s2pf	753	11	RNA	RNA	NNP
cord-256444-grw5s2pf	753	12	proofreading	proofreading	NN
cord-256444-grw5s2pf	753	13	activity	activity	NN
cord-256444-grw5s2pf	753	14	during	during	IN
cord-256444-grw5s2pf	753	15	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	753	16	transcription	transcription	NN
cord-256444-grw5s2pf	753	17	(	(	-LRB-
cord-256444-grw5s2pf	753	18	Lai	Lai	NNP
cord-256444-grw5s2pf	753	19	,	,	,
cord-256444-grw5s2pf	753	20	1986	1986	CD
cord-256444-grw5s2pf	753	21	(	(	-LRB-
cord-256444-grw5s2pf	753	22	Lai	Lai	NNP
cord-256444-grw5s2pf	753	23	,	,	,
cord-256444-grw5s2pf	753	24	,	,	,
cord-256444-grw5s2pf	753	25	1990	1990	CD
cord-256444-grw5s2pf	753	26	;	;	:
cord-256444-grw5s2pf	753	27	van	van	NNP
cord-256444-grw5s2pf	753	28	der	der	NNP
cord-256444-grw5s2pf	753	29	Most	Most	NNP
cord-256444-grw5s2pf	753	30	et	et	NNP
cord-256444-grw5s2pf	753	31	al	al	NNP
cord-256444-grw5s2pf	753	32	.	.	NNP
cord-256444-grw5s2pf	753	33	,	,	,
cord-256444-grw5s2pf	753	34	1994	1994	CD
cord-256444-grw5s2pf	753	35	)	)	-RRB-
cord-256444-grw5s2pf	753	36	.	.	.
cord-256444-grw5s2pf	754	1	The	the	DT
cord-256444-grw5s2pf	754	2	following	follow	VBG
cord-256444-grw5s2pf	754	3	transcriptional	transcriptional	JJ
cord-256444-grw5s2pf	754	4	models	model	NNS
cord-256444-grw5s2pf	754	5	(	(	-LRB-
cord-256444-grw5s2pf	754	6	Fig	Fig	NNP
cord-256444-grw5s2pf	754	7	.	.	.
cord-256444-grw5s2pf	754	8	8)	8)	NNP
cord-256444-grw5s2pf	754	9	address	address	VB
cord-256444-grw5s2pf	754	10	the	the	DT
cord-256444-grw5s2pf	754	11	possible	possible	JJ
cord-256444-grw5s2pf	754	12	mechanism	mechanism	NN
cord-256444-grw5s2pf	754	13	of	of	IN
cord-256444-grw5s2pf	754	14	fusion	fusion	NN
cord-256444-grw5s2pf	754	15	between	between	IN
cord-256444-grw5s2pf	754	16	the	the	DT
cord-256444-grw5s2pf	754	17	leader	leader	NN
cord-256444-grw5s2pf	754	18	sequence	sequence	NN
cord-256444-grw5s2pf	754	19	and	and	CC
cord-256444-grw5s2pf	754	20	mRNAs	mrna	NNS
cord-256444-grw5s2pf	754	21	.	.	.
cord-256444-grw5s2pf	755	1	Most	Most	JJS
cord-256444-grw5s2pf	755	2	of	of	IN
cord-256444-grw5s2pf	755	3	the	the	DT
cord-256444-grw5s2pf	755	4	experimental	experimental	JJ
cord-256444-grw5s2pf	755	5	evidence	evidence	NN
cord-256444-grw5s2pf	755	6	came	come	VBD
cord-256444-grw5s2pf	755	7	from	from	IN
cord-256444-grw5s2pf	755	8	MHV	MHV	NNP
cord-256444-grw5s2pf	755	9	studies	study	NNS
cord-256444-grw5s2pf	755	10	.	.	.
cord-256444-grw5s2pf	756	1	The	the	DT
cord-256444-grw5s2pf	756	2	exceptions	exception	NNS
cord-256444-grw5s2pf	756	3	will	will	MD
cord-256444-grw5s2pf	756	4	be	be	VB
cord-256444-grw5s2pf	756	5	noted	note	VBN
cord-256444-grw5s2pf	756	6	.	.	.
cord-256444-grw5s2pf	757	1	a.	a.	NNP
cord-256444-grw5s2pf	757	2	Leader	Leader	NNP
cord-256444-grw5s2pf	757	3	-	-	HYPH
cord-256444-grw5s2pf	757	4	Primed	prime	VBN
cord-256444-grw5s2pf	757	5	Transcription	Transcription	NNP
cord-256444-grw5s2pf	757	6	.	.	.
cord-256444-grw5s2pf	758	1	This	this	DT
cord-256444-grw5s2pf	758	2	model	model	NN
cord-256444-grw5s2pf	758	3	proposes	propose	VBZ
cord-256444-grw5s2pf	758	4	that	that	IN
cord-256444-grw5s2pf	758	5	the	the	DT
cord-256444-grw5s2pf	758	6	virion	virion	NN
cord-256444-grw5s2pf	758	7	genomic	genomic	JJ
cord-256444-grw5s2pf	758	8	RNA	RNA	NNP
cord-256444-grw5s2pf	758	9	is	be	VBZ
cord-256444-grw5s2pf	758	10	first	first	RB
cord-256444-grw5s2pf	758	11	transcribed	transcribe	VBN
cord-256444-grw5s2pf	758	12	into	into	IN
cord-256444-grw5s2pf	758	13	a	a	DT
cord-256444-grw5s2pf	758	14	genomic	genomic	NN
cord-256444-grw5s2pf	758	15	-	-	HYPH
cord-256444-grw5s2pf	758	16	length	length	NN
cord-256444-grw5s2pf	758	17	,	,	,
cord-256444-grw5s2pf	758	18	negativestrand	negativestrand	NNP
cord-256444-grw5s2pf	758	19	RNA	RNA	NNP
cord-256444-grw5s2pf	758	20	,	,	,
cord-256444-grw5s2pf	758	21	which	which	WDT
cord-256444-grw5s2pf	758	22	,	,	,
cord-256444-grw5s2pf	758	23	in	in	IN
cord-256444-grw5s2pf	758	24	turn	turn	NN
cord-256444-grw5s2pf	758	25	,	,	,
cord-256444-grw5s2pf	758	26	becomes	become	VBZ
cord-256444-grw5s2pf	758	27	the	the	DT
cord-256444-grw5s2pf	758	28	template	template	NN
cord-256444-grw5s2pf	758	29	for	for	IN
cord-256444-grw5s2pf	758	30	subsequent	subsequent	JJ
cord-256444-grw5s2pf	758	31	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	758	32	mRNA	mRNA	NNP
cord-256444-grw5s2pf	758	33	synthesis	synthesis	NN
cord-256444-grw5s2pf	758	34	.	.	.
cord-256444-grw5s2pf	759	1	The	the	DT
cord-256444-grw5s2pf	759	2	leader	leader	NN
cord-256444-grw5s2pf	759	3	RNA	RNA	NNP
cord-256444-grw5s2pf	759	4	is	be	VBZ
cord-256444-grw5s2pf	759	5	transcribed	transcribe	VBN
cord-256444-grw5s2pf	759	6	from	from	IN
cord-256444-grw5s2pf	759	7	the	the	DT
cord-256444-grw5s2pf	759	8	3	3	CD
cord-256444-grw5s2pf	759	9	'	'	NN
cord-256444-grw5s2pf	759	10	end	end	NN
cord-256444-grw5s2pf	759	11	of	of	IN
cord-256444-grw5s2pf	759	12	the	the	DT
cord-256444-grw5s2pf	759	13	negative	negative	JJ
cord-256444-grw5s2pf	759	14	-	-	HYPH
cord-256444-grw5s2pf	759	15	strand	strand	NN
cord-256444-grw5s2pf	759	16	RNA	RNA	NNP
cord-256444-grw5s2pf	759	17	and	and	CC
cord-256444-grw5s2pf	759	18	dissociated	dissociate	VBN
cord-256444-grw5s2pf	759	19	from	from	IN
cord-256444-grw5s2pf	759	20	the	the	DT
cord-256444-grw5s2pf	759	21	template	template	NN
cord-256444-grw5s2pf	759	22	.	.	.
cord-256444-grw5s2pf	760	1	The	the	DT
cord-256444-grw5s2pf	760	2	free	free	JJ
cord-256444-grw5s2pf	760	3	RNA	RNA	NNP
cord-256444-grw5s2pf	760	4	subsequently	subsequently	RB
cord-256444-grw5s2pf	760	5	associates	associate	VBZ
cord-256444-grw5s2pf	760	6	with	with	IN
cord-256444-grw5s2pf	760	7	the	the	DT
cord-256444-grw5s2pf	760	8	template	template	NN
cord-256444-grw5s2pf	760	9	RNA	RNA	NNP
cord-256444-grw5s2pf	760	10	at	at	IN
cord-256444-grw5s2pf	760	11	various	various	JJ
cord-256444-grw5s2pf	760	12	mRNA	mRNA	NNP
cord-256444-grw5s2pf	760	13	start	start	VB
cord-256444-grw5s2pf	760	14	sites	site	NNS
cord-256444-grw5s2pf	760	15	and	and	CC
cord-256444-grw5s2pf	760	16	serves	serve	VBZ
cord-256444-grw5s2pf	760	17	as	as	IN
cord-256444-grw5s2pf	760	18	a	a	DT
cord-256444-grw5s2pf	760	19	primer	primer	NN
cord-256444-grw5s2pf	760	20	for	for	IN
cord-256444-grw5s2pf	760	21	transcription	transcription	NN
cord-256444-grw5s2pf	760	22	of	of	IN
cord-256444-grw5s2pf	760	23	mRNAs	mrnas	CD
cord-256444-grw5s2pf	760	24	.	.	.
cord-256444-grw5s2pf	761	1	It	-PRON-	PRP
cord-256444-grw5s2pf	761	2	is	be	VBZ
cord-256444-grw5s2pf	761	3	proposed	propose	VBN
cord-256444-grw5s2pf	761	4	that	that	IN
cord-256444-grw5s2pf	761	5	the	the	DT
cord-256444-grw5s2pf	761	6	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	761	7	transcription	transcription	NN
cord-256444-grw5s2pf	761	8	step	step	NN
cord-256444-grw5s2pf	761	9	takes	take	VBZ
cord-256444-grw5s2pf	761	10	place	place	NN
cord-256444-grw5s2pf	761	11	during	during	IN
cord-256444-grw5s2pf	761	12	positive	positive	JJ
cord-256444-grw5s2pf	761	13	-	-	HYPH
cord-256444-grw5s2pf	761	14	strand	strand	NN
cord-256444-grw5s2pf	761	15	RNA	RNA	NNP
cord-256444-grw5s2pf	761	16	synthesis	synthesis	NN
cord-256444-grw5s2pf	761	17	.	.	.
cord-256444-grw5s2pf	762	1	Several	several	JJ
cord-256444-grw5s2pf	762	2	pieces	piece	NNS
cord-256444-grw5s2pf	762	3	of	of	IN
cord-256444-grw5s2pf	762	4	evidence	evidence	NN
cord-256444-grw5s2pf	762	5	are	be	VBP
cord-256444-grw5s2pf	762	6	compatible	compatible	JJ
cord-256444-grw5s2pf	762	7	with	with	IN
cord-256444-grw5s2pf	762	8	this	this	DT
cord-256444-grw5s2pf	762	9	model	model	NN
cord-256444-grw5s2pf	762	10	:	:	:
cord-256444-grw5s2pf	762	11	detected	detect	VBN
cord-256444-grw5s2pf	762	12	in	in	IN
cord-256444-grw5s2pf	762	13	the	the	DT
cord-256444-grw5s2pf	762	14	cytoplasm	cytoplasm	NN
cord-256444-grw5s2pf	762	15	of	of	IN
cord-256444-grw5s2pf	762	16	MHV	mhv	NN
cord-256444-grw5s2pf	762	17	-	-	HYPH
cord-256444-grw5s2pf	762	18	infected	infect	VBN
cord-256444-grw5s2pf	762	19	cells	cell	NNS
cord-256444-grw5s2pf	763	1	(	(	-LRB-
cord-256444-grw5s2pf	763	2	Baric	Baric	NNP
cord-256444-grw5s2pf	763	3	et	et	NNP
cord-256444-grw5s2pf	763	4	al	al	NNP
cord-256444-grw5s2pf	763	5	.	.	NNP
cord-256444-grw5s2pf	763	6	,	,	,
cord-256444-grw5s2pf	763	7	1985	1985	CD
cord-256444-grw5s2pf	763	8	)	)	-RRB-
cord-256444-grw5s2pf	763	9	.	.	.
cord-256444-grw5s2pf	764	1	Some	some	DT
cord-256444-grw5s2pf	764	2	of	of	IN
cord-256444-grw5s2pf	764	3	these	these	DT
cord-256444-grw5s2pf	764	4	are	be	VBP
cord-256444-grw5s2pf	764	5	dissociated	dissociate	VBN
cord-256444-grw5s2pf	764	6	from	from	IN
cord-256444-grw5s2pf	764	7	the	the	DT
cord-256444-grw5s2pf	764	8	template	template	NN
cord-256444-grw5s2pf	764	9	RNA	RNA	NNP
cord-256444-grw5s2pf	764	10	and	and	CC
cord-256444-grw5s2pf	764	11	,	,	,
cord-256444-grw5s2pf	764	12	thus	thus	RB
cord-256444-grw5s2pf	764	13	,	,	,
cord-256444-grw5s2pf	764	14	may	may	MD
cord-256444-grw5s2pf	764	15	serve	serve	VB
cord-256444-grw5s2pf	764	16	as	as	IN
cord-256444-grw5s2pf	764	17	a	a	DT
cord-256444-grw5s2pf	764	18	potential	potential	JJ
cord-256444-grw5s2pf	764	19	source	source	NN
cord-256444-grw5s2pf	764	20	of	of	IN
cord-256444-grw5s2pf	764	21	primers	primer	NNS
cord-256444-grw5s2pf	764	22	in	in	IN
cord-256444-grw5s2pf	764	23	this	this	DT
cord-256444-grw5s2pf	764	24	transcription	transcription	NN
cord-256444-grw5s2pf	764	25	model	model	NN
cord-256444-grw5s2pf	764	26	.	.	.
cord-256444-grw5s2pf	765	1	These	these	DT
cord-256444-grw5s2pf	765	2	RNAs	rna	NNS
cord-256444-grw5s2pf	765	3	have	have	VBP
cord-256444-grw5s2pf	765	4	distinct	distinct	JJ
cord-256444-grw5s2pf	765	5	sizes	size	NNS
cord-256444-grw5s2pf	765	6	which	which	WDT
cord-256444-grw5s2pf	765	7	are	be	VBP
cord-256444-grw5s2pf	765	8	reproducible	reproducible	JJ
cord-256444-grw5s2pf	765	9	from	from	IN
cord-256444-grw5s2pf	765	10	cell	cell	NN
cord-256444-grw5s2pf	765	11	to	to	IN
cord-256444-grw5s2pf	765	12	cell	cell	NN
cord-256444-grw5s2pf	766	1	(	(	-LRB-
cord-256444-grw5s2pf	766	2	Baric	Baric	NNP
cord-256444-grw5s2pf	766	3	et	et	NNP
cord-256444-grw5s2pf	766	4	al	al	NNP
cord-256444-grw5s2pf	766	5	.	.	NNP
cord-256444-grw5s2pf	766	6	,	,	,
cord-256444-grw5s2pf	766	7	1987	1987	CD
cord-256444-grw5s2pf	766	8	)	)	-RRB-
cord-256444-grw5s2pf	766	9	;	;	:
cord-256444-grw5s2pf	766	10	however	however	RB
cord-256444-grw5s2pf	766	11	,	,	,
cord-256444-grw5s2pf	766	12	they	-PRON-	PRP
cord-256444-grw5s2pf	766	13	are	be	VBP
cord-256444-grw5s2pf	766	14	not	not	RB
cord-256444-grw5s2pf	766	15	exactly	exactly	RB
cord-256444-grw5s2pf	766	16	the	the	DT
cord-256444-grw5s2pf	766	17	same	same	JJ
cord-256444-grw5s2pf	766	18	size	size	NN
cord-256444-grw5s2pf	766	19	as	as	IN
cord-256444-grw5s2pf	766	20	the	the	DT
cord-256444-grw5s2pf	766	21	leader	leader	NN
cord-256444-grw5s2pf	766	22	sequence	sequence	NN
cord-256444-grw5s2pf	766	23	present	present	JJ
cord-256444-grw5s2pf	766	24	in	in	IN
cord-256444-grw5s2pf	766	25	the	the	DT
cord-256444-grw5s2pf	766	26	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	766	27	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	766	28	.	.	.
cord-256444-grw5s2pf	767	1	Thus	thus	RB
cord-256444-grw5s2pf	767	2	,	,	,
cord-256444-grw5s2pf	767	3	these	these	DT
cord-256444-grw5s2pf	767	4	free	free	JJ
cord-256444-grw5s2pf	767	5	leader	leader	NN
cord-256444-grw5s2pf	767	6	RNAs	rna	NNS
cord-256444-grw5s2pf	767	7	must	must	MD
cord-256444-grw5s2pf	767	8	be	be	VB
cord-256444-grw5s2pf	767	9	processed	process	VBN
cord-256444-grw5s2pf	767	10	before	before	IN
cord-256444-grw5s2pf	767	11	they	-PRON-	PRP
cord-256444-grw5s2pf	767	12	are	be	VBP
cord-256444-grw5s2pf	767	13	incorporated	incorporate	VBN
cord-256444-grw5s2pf	767	14	into	into	IN
cord-256444-grw5s2pf	767	15	mRNAs	mrnas	PRP
cord-256444-grw5s2pf	767	16	.	.	.
cord-256444-grw5s2pf	768	1	A	a	DT
cord-256444-grw5s2pf	768	2	temperature	temperature	NN
cord-256444-grw5s2pf	768	3	-	-	HYPH
cord-256444-grw5s2pf	768	4	sensitive	sensitive	JJ
cord-256444-grw5s2pf	768	5	mutant	mutant	NN
cord-256444-grw5s2pf	768	6	of	of	IN
cord-256444-grw5s2pf	768	7	MHV	MHV	NNP
cord-256444-grw5s2pf	768	8	,	,	,
cord-256444-grw5s2pf	768	9	which	which	WDT
cord-256444-grw5s2pf	768	10	synthesizes	synthesize	VBZ
cord-256444-grw5s2pf	768	11	leader	leader	NN
cord-256444-grw5s2pf	768	12	RNA	RNA	NNP
cord-256444-grw5s2pf	768	13	but	but	CC
cord-256444-grw5s2pf	768	14	not	not	RB
cord-256444-grw5s2pf	768	15	mRNAs	mrna	NNS
cord-256444-grw5s2pf	768	16	at	at	IN
cord-256444-grw5s2pf	768	17	the	the	DT
cord-256444-grw5s2pf	768	18	nonpermissive	nonpermissive	JJ
cord-256444-grw5s2pf	768	19	temperature	temperature	NN
cord-256444-grw5s2pf	768	20	,	,	,
cord-256444-grw5s2pf	768	21	has	have	VBZ
cord-256444-grw5s2pf	768	22	been	be	VBN
cord-256444-grw5s2pf	768	23	isolated	isolate	VBN
cord-256444-grw5s2pf	768	24	.	.	.
cord-256444-grw5s2pf	769	1	The	the	DT
cord-256444-grw5s2pf	769	2	isolation	isolation	NN
cord-256444-grw5s2pf	769	3	of	of	IN
cord-256444-grw5s2pf	769	4	this	this	DT
cord-256444-grw5s2pf	769	5	mutant	mutant	NN
cord-256444-grw5s2pf	769	6	suggests	suggest	VBZ
cord-256444-grw5s2pf	769	7	that	that	IN
cord-256444-grw5s2pf	769	8	MHV	MHV	NNP
cord-256444-grw5s2pf	769	9	mRNA	mRNA	NNP
cord-256444-grw5s2pf	769	10	synthesis	synthesis	NN
cord-256444-grw5s2pf	769	11	is	be	VBZ
cord-256444-grw5s2pf	769	12	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	769	13	,	,	,
cord-256444-grw5s2pf	769	14	requiring	require	VBG
cord-256444-grw5s2pf	769	15	different	different	JJ
cord-256444-grw5s2pf	769	16	viral	viral	JJ
cord-256444-grw5s2pf	769	17	proteins	protein	NNS
cord-256444-grw5s2pf	769	18	for	for	IN
cord-256444-grw5s2pf	769	19	the	the	DT
cord-256444-grw5s2pf	769	20	synthesis	synthesis	NN
cord-256444-grw5s2pf	769	21	of	of	IN
cord-256444-grw5s2pf	769	22	leader	leader	NN
cord-256444-grw5s2pf	769	23	RNA	RNA	NNP
cord-256444-grw5s2pf	769	24	and	and	CC
cord-256444-grw5s2pf	769	25	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	769	26	.	.	.
cord-256444-grw5s2pf	770	1	Thus	thus	RB
cord-256444-grw5s2pf	770	2	,	,	,
cord-256444-grw5s2pf	770	3	a	a	DT
cord-256444-grw5s2pf	770	4	distinction	distinction	NN
cord-256444-grw5s2pf	770	5	can	can	MD
cord-256444-grw5s2pf	770	6	be	be	VB
cord-256444-grw5s2pf	770	7	made	make	VBN
cord-256444-grw5s2pf	770	8	between	between	IN
cord-256444-grw5s2pf	770	9	leader	leader	NN
cord-256444-grw5s2pf	770	10	RNA	RNA	NNP
cord-256444-grw5s2pf	770	11	synthesis	synthesis	NN
cord-256444-grw5s2pf	770	12	and	and	CC
cord-256444-grw5s2pf	770	13	mRNA	mRNA	NNP
cord-256444-grw5s2pf	770	14	synthesis	synthesis	NN
cord-256444-grw5s2pf	770	15	.	.	.
cord-256444-grw5s2pf	771	1	of	of	IN
cord-256444-grw5s2pf	771	2	the	the	DT
cord-256444-grw5s2pf	771	3	viruses	virus	NNS
cord-256444-grw5s2pf	771	4	is	be	VBZ
cord-256444-grw5s2pf	771	5	derived	derive	VBN
cord-256444-grw5s2pf	771	6	from	from	IN
cord-256444-grw5s2pf	771	7	the	the	DT
cord-256444-grw5s2pf	771	8	other	other	JJ
cord-256444-grw5s2pf	771	9	coinfecting	coinfecte	VBG
cord-256444-grw5s2pf	771	10	virus	virus	NN
cord-256444-grw5s2pf	771	11	(	(	-LRB-
cord-256444-grw5s2pf	771	12	Makino	Makino	NNP
cord-256444-grw5s2pf	771	13	et	et	NNP
cord-256444-grw5s2pf	771	14	al	al	NNP
cord-256444-grw5s2pf	771	15	.	.	NNP
cord-256444-grw5s2pf	771	16	,	,	,
cord-256444-grw5s2pf	771	17	1986b	1986b	CD
cord-256444-grw5s2pf	771	18	)	)	-RRB-
cord-256444-grw5s2pf	771	19	.	.	.
cord-256444-grw5s2pf	772	1	This	this	DT
cord-256444-grw5s2pf	772	2	result	result	NN
cord-256444-grw5s2pf	772	3	suggests	suggest	VBZ
cord-256444-grw5s2pf	772	4	that	that	IN
cord-256444-grw5s2pf	772	5	the	the	DT
cord-256444-grw5s2pf	772	6	leader	leader	NN
cord-256444-grw5s2pf	772	7	sequence	sequence	NN
cord-256444-grw5s2pf	772	8	and	and	CC
cord-256444-grw5s2pf	772	9	body	body	NN
cord-256444-grw5s2pf	772	10	sequence	sequence	NN
cord-256444-grw5s2pf	772	11	of	of	IN
cord-256444-grw5s2pf	772	12	each	each	DT
cord-256444-grw5s2pf	772	13	mRNA	mrna	NN
cord-256444-grw5s2pf	772	14	are	be	VBP
cord-256444-grw5s2pf	772	15	derived	derive	VBN
cord-256444-grw5s2pf	772	16	from	from	IN
cord-256444-grw5s2pf	772	17	two	two	CD
cord-256444-grw5s2pf	772	18	separate	separate	JJ
cord-256444-grw5s2pf	772	19	pools	pool	NNS
cord-256444-grw5s2pf	772	20	.	.	.
cord-256444-grw5s2pf	773	1	This	this	DT
cord-256444-grw5s2pf	773	2	phenomenon	phenomenon	NN
cord-256444-grw5s2pf	773	3	is	be	VBZ
cord-256444-grw5s2pf	773	4	reminiscent	reminiscent	JJ
cord-256444-grw5s2pf	773	5	of	of	IN
cord-256444-grw5s2pf	773	6	the	the	DT
cord-256444-grw5s2pf	773	7	RNA	RNA	NNP
cord-256444-grw5s2pf	773	8	reassortment	reassortment	NN
cord-256444-grw5s2pf	773	9	that	that	WDT
cord-256444-grw5s2pf	773	10	occurs	occur	VBZ
cord-256444-grw5s2pf	773	11	in	in	IN
cord-256444-grw5s2pf	773	12	RNA	RNA	NNP
cord-256444-grw5s2pf	773	13	viruses	virus	NNS
cord-256444-grw5s2pf	773	14	with	with	IN
cord-256444-grw5s2pf	773	15	segmented	segmented	JJ
cord-256444-grw5s2pf	773	16	RNA	RNA	NNP
cord-256444-grw5s2pf	773	17	genomes	genome	NNS
cord-256444-grw5s2pf	773	18	.	.	.
cord-256444-grw5s2pf	774	1	This	this	DT
cord-256444-grw5s2pf	774	2	result	result	NN
cord-256444-grw5s2pf	774	3	is	be	VBZ
cord-256444-grw5s2pf	774	4	best	well	RBS
cord-256444-grw5s2pf	774	5	explained	explain	VBN
cord-256444-grw5s2pf	774	6	by	by	IN
cord-256444-grw5s2pf	774	7	the	the	DT
cord-256444-grw5s2pf	774	8	possibility	possibility	NN
cord-256444-grw5s2pf	774	9	that	that	IN
cord-256444-grw5s2pf	774	10	free	free	JJ
cord-256444-grw5s2pf	774	11	leader	leader	NN
cord-256444-grw5s2pf	774	12	RNAs	rna	NNS
cord-256444-grw5s2pf	774	13	participate	participate	VBP
cord-256444-grw5s2pf	774	14	in	in	IN
cord-256444-grw5s2pf	774	15	viral	viral	JJ
cord-256444-grw5s2pf	774	16	RNA	RNA	NNP
cord-256444-grw5s2pf	774	17	synthesis	synthesis	NN
cord-256444-grw5s2pf	774	18	.	.	.
cord-256444-grw5s2pf	775	1	In	in	IN
cord-256444-grw5s2pf	775	2	an	an	DT
cord-256444-grw5s2pf	775	3	in	in	FW
cord-256444-grw5s2pf	775	4	vitro	vitro	FW
cord-256444-grw5s2pf	775	5	transcription	transcription	NN
cord-256444-grw5s2pf	775	6	system	system	NN
cord-256444-grw5s2pf	775	7	utilizing	utilize	VBG
cord-256444-grw5s2pf	775	8	cytoplasmic	cytoplasmic	JJ
cord-256444-grw5s2pf	775	9	extracts	extract	NNS
cord-256444-grw5s2pf	775	10	from	from	IN
cord-256444-grw5s2pf	775	11	MHV	mhv	NN
cord-256444-grw5s2pf	775	12	-	-	HYPH
cord-256444-grw5s2pf	775	13	infected	infect	VBN
cord-256444-grw5s2pf	775	14	cells	cell	NNS
cord-256444-grw5s2pf	775	15	,	,	,
cord-256444-grw5s2pf	775	16	exogenous	exogenous	JJ
cord-256444-grw5s2pf	775	17	leader	leader	NN
cord-256444-grw5s2pf	775	18	RNAs	rna	NNS
cord-256444-grw5s2pf	775	19	can	can	MD
cord-256444-grw5s2pf	775	20	be	be	VB
cord-256444-grw5s2pf	775	21	utilized	utilize	VBN
cord-256444-grw5s2pf	775	22	for	for	IN
cord-256444-grw5s2pf	775	23	mRNA	mRNA	NNP
cord-256444-grw5s2pf	775	24	synthesis	synthesis	NN
cord-256444-grw5s2pf	775	25	(	(	-LRB-
cord-256444-grw5s2pf	775	26	Baker	Baker	NNP
cord-256444-grw5s2pf	775	27	and	and	CC
cord-256444-grw5s2pf	775	28	Lai	Lai	NNP
cord-256444-grw5s2pf	775	29	,	,	,
cord-256444-grw5s2pf	775	30	1990	1990	CD
cord-256444-grw5s2pf	775	31	)	)	-RRB-
cord-256444-grw5s2pf	775	32	.	.	.
cord-256444-grw5s2pf	776	1	The	the	DT
cord-256444-grw5s2pf	776	2	exogenous	exogenous	JJ
cord-256444-grw5s2pf	776	3	leader	leader	NN
cord-256444-grw5s2pf	776	4	RNA	RNA	NNP
cord-256444-grw5s2pf	776	5	was	be	VBD
cord-256444-grw5s2pf	776	6	incorporated	incorporate	VBN
cord-256444-grw5s2pf	776	7	into	into	IN
cord-256444-grw5s2pf	776	8	the	the	DT
cord-256444-grw5s2pf	776	9	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	776	10	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	776	11	at	at	IN
cord-256444-grw5s2pf	776	12	a	a	DT
cord-256444-grw5s2pf	776	13	site	site	NN
cord-256444-grw5s2pf	776	14	that	that	WDT
cord-256444-grw5s2pf	776	15	matched	match	VBD
cord-256444-grw5s2pf	776	16	precisely	precisely	RB
cord-256444-grw5s2pf	776	17	that	that	DT
cord-256444-grw5s2pf	776	18	of	of	IN
cord-256444-grw5s2pf	776	19	the	the	DT
cord-256444-grw5s2pf	776	20	endogenous	endogenous	JJ
cord-256444-grw5s2pf	776	21	leader	leader	NN
cord-256444-grw5s2pf	776	22	RNA	RNA	NNP
cord-256444-grw5s2pf	776	23	present	present	JJ
cord-256444-grw5s2pf	776	24	in	in	IN
cord-256444-grw5s2pf	776	25	the	the	DT
cord-256444-grw5s2pf	776	26	viral	viral	JJ
cord-256444-grw5s2pf	776	27	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	776	28	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	776	29	,	,	,
cord-256444-grw5s2pf	776	30	regardless	regardless	RB
cord-256444-grw5s2pf	776	31	of	of	IN
cord-256444-grw5s2pf	776	32	the	the	DT
cord-256444-grw5s2pf	776	33	length	length	NN
cord-256444-grw5s2pf	776	34	of	of	IN
cord-256444-grw5s2pf	776	35	the	the	DT
cord-256444-grw5s2pf	776	36	exogenous	exogenous	JJ
cord-256444-grw5s2pf	776	37	leader	leader	NN
cord-256444-grw5s2pf	776	38	RNA	RNA	NNP
cord-256444-grw5s2pf	776	39	used	use	VBD
cord-256444-grw5s2pf	776	40	,	,	,
cord-256444-grw5s2pf	776	41	suggesting	suggest	VBG
cord-256444-grw5s2pf	776	42	that	that	IN
cord-256444-grw5s2pf	776	43	the	the	DT
cord-256444-grw5s2pf	776	44	exogenous	exogenous	JJ
cord-256444-grw5s2pf	776	45	leader	leader	NN
cord-256444-grw5s2pf	776	46	RNA	RNA	NNP
cord-256444-grw5s2pf	776	47	sequence	sequence	NN
cord-256444-grw5s2pf	776	48	was	be	VBD
cord-256444-grw5s2pf	776	49	processed	process	VBN
cord-256444-grw5s2pf	776	50	before	before	IN
cord-256444-grw5s2pf	776	51	being	be	VBG
cord-256444-grw5s2pf	776	52	incorporated	incorporate	VBN
cord-256444-grw5s2pf	776	53	into	into	IN
cord-256444-grw5s2pf	776	54	mRNAs	mrnas	PRP
cord-256444-grw5s2pf	776	55	.	.	.
cord-256444-grw5s2pf	777	1	Furthermore	furthermore	RB
cord-256444-grw5s2pf	777	2	,	,	,
cord-256444-grw5s2pf	777	3	the	the	DT
cord-256444-grw5s2pf	777	4	truncated	truncated	JJ
cord-256444-grw5s2pf	777	5	leader	leader	NN
cord-256444-grw5s2pf	777	6	RNA	RNA	NNP
cord-256444-grw5s2pf	777	7	which	which	WDT
cord-256444-grw5s2pf	777	8	lacked	lack	VBD
cord-256444-grw5s2pf	777	9	the	the	DT
cord-256444-grw5s2pf	777	10	3	3	CD
cord-256444-grw5s2pf	777	11	'	'	''
cord-256444-grw5s2pf	777	12	end	end	NN
cord-256444-grw5s2pf	777	13	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	777	14	sequence	sequence	NN
cord-256444-grw5s2pf	777	15	could	could	MD
cord-256444-grw5s2pf	777	16	not	not	RB
cord-256444-grw5s2pf	777	17	be	be	VB
cord-256444-grw5s2pf	777	18	incorporated	incorporate	VBN
cord-256444-grw5s2pf	777	19	into	into	IN
cord-256444-grw5s2pf	777	20	mRNAs	mrnas	CD
cord-256444-grw5s2pf	777	21	,	,	,
cord-256444-grw5s2pf	777	22	suggesting	suggest	VBG
cord-256444-grw5s2pf	777	23	the	the	DT
cord-256444-grw5s2pf	777	24	importance	importance	NN
cord-256444-grw5s2pf	777	25	of	of	IN
cord-256444-grw5s2pf	777	26	this	this	DT
cord-256444-grw5s2pf	777	27	sequence	sequence	NN
cord-256444-grw5s2pf	777	28	in	in	IN
cord-256444-grw5s2pf	777	29	transcription	transcription	NN
cord-256444-grw5s2pf	777	30	(	(	-LRB-
cord-256444-grw5s2pf	777	31	Baker	Baker	NNP
cord-256444-grw5s2pf	777	32	and	and	CC
cord-256444-grw5s2pf	777	33	Lai	Lai	NNP
cord-256444-grw5s2pf	777	34	,	,	,
cord-256444-grw5s2pf	777	35	1990	1990	CD
cord-256444-grw5s2pf	777	36	)	)	-RRB-
cord-256444-grw5s2pf	777	37	.	.	.
cord-256444-grw5s2pf	778	1	5	5	LS
cord-256444-grw5s2pf	778	2	.	.	.
cord-256444-grw5s2pf	779	1	The	the	DT
cord-256444-grw5s2pf	779	2	leader	leader	NN
cord-256444-grw5s2pf	779	3	RNA	RNA	NNP
cord-256444-grw5s2pf	779	4	sequence	sequence	NN
cord-256444-grw5s2pf	779	5	,	,	,
cord-256444-grw5s2pf	779	6	specifically	specifically	RB
cord-256444-grw5s2pf	779	7	the	the	DT
cord-256444-grw5s2pf	779	8	copy	copy	JJ
cord-256444-grw5s2pf	779	9	number	number	NN
cord-256444-grw5s2pf	779	10	of	of	IN
cord-256444-grw5s2pf	779	11	the	the	DT
cord-256444-grw5s2pf	779	12	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	779	13	repeats	repeat	VBZ
cord-256444-grw5s2pf	779	14	at	at	IN
cord-256444-grw5s2pf	779	15	the	the	DT
cord-256444-grw5s2pf	779	16	3	3	CD
cord-256444-grw5s2pf	779	17	'	'	NN
cord-256444-grw5s2pf	779	18	end	end	NN
cord-256444-grw5s2pf	779	19	of	of	IN
cord-256444-grw5s2pf	779	20	the	the	DT
cord-256444-grw5s2pf	779	21	leader	leader	NN
cord-256444-grw5s2pf	779	22	RNA	RNA	NNP
cord-256444-grw5s2pf	779	23	,	,	,
cord-256444-grw5s2pf	779	24	can	can	MD
cord-256444-grw5s2pf	779	25	affect	affect	VB
cord-256444-grw5s2pf	779	26	the	the	DT
cord-256444-grw5s2pf	779	27	transcription	transcription	NN
cord-256444-grw5s2pf	779	28	of	of	IN
cord-256444-grw5s2pf	779	29	some	some	DT
cord-256444-grw5s2pf	779	30	viral	viral	JJ
cord-256444-grw5s2pf	779	31	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	779	32	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	779	33	.	.	.
cord-256444-grw5s2pf	780	1	For	for	IN
cord-256444-grw5s2pf	780	2	example	example	NN
cord-256444-grw5s2pf	780	3	,	,	,
cord-256444-grw5s2pf	780	4	whereas	whereas	IN
cord-256444-grw5s2pf	780	5	an	an	DT
cord-256444-grw5s2pf	780	6	MHV	MHV	NNP
cord-256444-grw5s2pf	780	7	strain	strain	NN
cord-256444-grw5s2pf	780	8	containing	contain	VBG
cord-256444-grw5s2pf	780	9	two	two	CD
cord-256444-grw5s2pf	780	10	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	780	11	repeats	repeat	VBZ
cord-256444-grw5s2pf	780	12	transcribes	transcribe	VBZ
cord-256444-grw5s2pf	780	13	mRNA	mRNA	NNP
cord-256444-grw5s2pf	780	14	2	2	CD
cord-256444-grw5s2pf	780	15	-	-	SYM
cord-256444-grw5s2pf	780	16	1	1	CD
cord-256444-grw5s2pf	780	17	,	,	,
cord-256444-grw5s2pf	780	18	a	a	DT
cord-256444-grw5s2pf	780	19	strain	strain	NN
cord-256444-grw5s2pf	780	20	with	with	IN
cord-256444-grw5s2pf	780	21	three	three	CD
cord-256444-grw5s2pf	780	22	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	780	23	repeats	repeat	VBZ
cord-256444-grw5s2pf	781	1	does	do	VBZ
cord-256444-grw5s2pf	781	2	not	not	RB
cord-256444-grw5s2pf	781	3	,	,	,
cord-256444-grw5s2pf	781	4	despite	despite	IN
cord-256444-grw5s2pf	781	5	identical	identical	JJ
cord-256444-grw5s2pf	781	6	sequences	sequence	NNS
cord-256444-grw5s2pf	781	7	in	in	IN
cord-256444-grw5s2pf	781	8	the	the	DT
cord-256444-grw5s2pf	781	9	mRNA	mRNA	NNP
cord-256444-grw5s2pf	781	10	start	start	NN
cord-256444-grw5s2pf	781	11	sites	site	NNS
cord-256444-grw5s2pf	781	12	of	of	IN
cord-256444-grw5s2pf	781	13	these	these	DT
cord-256444-grw5s2pf	781	14	two	two	CD
cord-256444-grw5s2pf	781	15	viruses	virus	NNS
cord-256444-grw5s2pf	781	16	La	La	NNP
cord-256444-grw5s2pf	781	17	Monica	Monica	NNP
cord-256444-grw5s2pf	781	18	et	et	NNP
cord-256444-grw5s2pf	781	19	al	al	NNP
cord-256444-grw5s2pf	781	20	.	.	NNP
cord-256444-grw5s2pf	781	21	,	,	,
cord-256444-grw5s2pf	781	22	1992	1992	CD
cord-256444-grw5s2pf	781	23	)	)	-RRB-
cord-256444-grw5s2pf	781	24	.	.	.
cord-256444-grw5s2pf	782	1	This	this	DT
cord-256444-grw5s2pf	782	2	finding	finding	NN
cord-256444-grw5s2pf	782	3	suggests	suggest	VBZ
cord-256444-grw5s2pf	782	4	that	that	IN
cord-256444-grw5s2pf	782	5	the	the	DT
cord-256444-grw5s2pf	782	6	leader	leader	NN
cord-256444-grw5s2pf	782	7	RNA	RNA	NNP
cord-256444-grw5s2pf	782	8	plays	play	VBZ
cord-256444-grw5s2pf	782	9	an	an	DT
cord-256444-grw5s2pf	782	10	essential	essential	JJ
cord-256444-grw5s2pf	782	11	role	role	NN
cord-256444-grw5s2pf	782	12	in	in	IN
cord-256444-grw5s2pf	782	13	the	the	DT
cord-256444-grw5s2pf	782	14	regulation	regulation	NN
cord-256444-grw5s2pf	782	15	of	of	IN
cord-256444-grw5s2pf	782	16	mRNA	mRNA	NNP
cord-256444-grw5s2pf	782	17	transcription	transcription	NN
cord-256444-grw5s2pf	782	18	.	.	.
cord-256444-grw5s2pf	783	1	According	accord	VBG
cord-256444-grw5s2pf	783	2	to	to	IN
cord-256444-grw5s2pf	783	3	this	this	DT
cord-256444-grw5s2pf	783	4	model	model	NN
cord-256444-grw5s2pf	783	5	,	,	,
cord-256444-grw5s2pf	783	6	the	the	DT
cord-256444-grw5s2pf	783	7	free	free	JJ
cord-256444-grw5s2pf	783	8	leader	leader	NN
cord-256444-grw5s2pf	783	9	RNA	RNA	NNP
cord-256444-grw5s2pf	783	10	binds	bind	VBZ
cord-256444-grw5s2pf	783	11	to	to	IN
cord-256444-grw5s2pf	783	12	the	the	DT
cord-256444-grw5s2pf	783	13	mRNA	mRNA	NNP
cord-256444-grw5s2pf	783	14	start	start	NN
cord-256444-grw5s2pf	783	15	site	site	NN
cord-256444-grw5s2pf	783	16	(	(	-LRB-
cord-256444-grw5s2pf	783	17	IG	IG	NNP
cord-256444-grw5s2pf	783	18	)	)	-RRB-
cord-256444-grw5s2pf	783	19	of	of	IN
cord-256444-grw5s2pf	783	20	the	the	DT
cord-256444-grw5s2pf	783	21	full	full	JJ
cord-256444-grw5s2pf	783	22	-	-	HYPH
cord-256444-grw5s2pf	783	23	length	length	NN
cord-256444-grw5s2pf	783	24	negative	negative	JJ
cord-256444-grw5s2pf	783	25	-	-	HYPH
cord-256444-grw5s2pf	783	26	strand	strand	NN
cord-256444-grw5s2pf	783	27	template	template	NN
cord-256444-grw5s2pf	783	28	via	via	IN
cord-256444-grw5s2pf	783	29	the	the	DT
cord-256444-grw5s2pf	783	30	complementary	complementary	JJ
cord-256444-grw5s2pf	783	31	sequences	sequence	NNS
cord-256444-grw5s2pf	783	32	between	between	IN
cord-256444-grw5s2pf	783	33	the	the	DT
cord-256444-grw5s2pf	783	34	3	3	CD
cord-256444-grw5s2pf	783	35	'	'	NN
cord-256444-grw5s2pf	783	36	end	end	NN
cord-256444-grw5s2pf	783	37	of	of	IN
cord-256444-grw5s2pf	783	38	the	the	DT
cord-256444-grw5s2pf	783	39	leader	leader	NN
cord-256444-grw5s2pf	783	40	(	(	-LRB-
cord-256444-grw5s2pf	783	41	positive	positive	JJ
cord-256444-grw5s2pf	783	42	-	-	HYPH
cord-256444-grw5s2pf	783	43	strand	strand	NN
cord-256444-grw5s2pf	783	44	)	)	-RRB-
cord-256444-grw5s2pf	783	45	and	and	CC
cord-256444-grw5s2pf	783	46	the	the	DT
cord-256444-grw5s2pf	783	47	IG	IG	NNP
cord-256444-grw5s2pf	783	48	site	site	NN
cord-256444-grw5s2pf	783	49	of	of	IN
cord-256444-grw5s2pf	783	50	the	the	DT
cord-256444-grw5s2pf	783	51	template	template	NN
cord-256444-grw5s2pf	783	52	RNA	RNA	NNP
cord-256444-grw5s2pf	783	53	(	(	-LRB-
cord-256444-grw5s2pf	783	54	negative	negative	JJ
cord-256444-grw5s2pf	783	55	-	-	HYPH
cord-256444-grw5s2pf	783	56	strand	strand	NN
cord-256444-grw5s2pf	783	57	)	)	-RRB-
cord-256444-grw5s2pf	783	58	and	and	CC
cord-256444-grw5s2pf	783	59	serves	serve	VBZ
cord-256444-grw5s2pf	783	60	as	as	IN
cord-256444-grw5s2pf	783	61	the	the	DT
cord-256444-grw5s2pf	783	62	primer	primer	NN
cord-256444-grw5s2pf	783	63	for	for	IN
cord-256444-grw5s2pf	783	64	RNA	RNA	NNP
cord-256444-grw5s2pf	783	65	transcription	transcription	NN
cord-256444-grw5s2pf	783	66	.	.	.
cord-256444-grw5s2pf	784	1	The	the	DT
cord-256444-grw5s2pf	784	2	free	free	JJ
cord-256444-grw5s2pf	784	3	leader	leader	NN
cord-256444-grw5s2pf	784	4	RNA	RNA	NNP
cord-256444-grw5s2pf	784	5	(	(	-LRB-
cord-256444-grw5s2pf	784	6	primer	primer	NN
cord-256444-grw5s2pf	784	7	)	)	-RRB-
cord-256444-grw5s2pf	784	8	may	may	MD
cord-256444-grw5s2pf	784	9	be	be	VB
cord-256444-grw5s2pf	784	10	longer	long	JJR
cord-256444-grw5s2pf	784	11	than	than	IN
cord-256444-grw5s2pf	784	12	the	the	DT
cord-256444-grw5s2pf	784	13	leader	leader	NN
cord-256444-grw5s2pf	784	14	sequence	sequence	NN
cord-256444-grw5s2pf	784	15	in	in	IN
cord-256444-grw5s2pf	784	16	the	the	DT
cord-256444-grw5s2pf	784	17	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	784	18	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	784	19	.	.	.
cord-256444-grw5s2pf	785	1	There	there	EX
cord-256444-grw5s2pf	785	2	are	be	VBP
cord-256444-grw5s2pf	785	3	certain	certain	JJ
cord-256444-grw5s2pf	785	4	mismatched	mismatched	JJ
cord-256444-grw5s2pf	785	5	nucleotides	nucleotide	NNS
cord-256444-grw5s2pf	785	6	between	between	IN
cord-256444-grw5s2pf	785	7	the	the	DT
cord-256444-grw5s2pf	785	8	leader	leader	NN
cord-256444-grw5s2pf	785	9	and	and	CC
cord-256444-grw5s2pf	785	10	template	template	NN
cord-256444-grw5s2pf	785	11	at	at	IN
cord-256444-grw5s2pf	785	12	some	some	DT
cord-256444-grw5s2pf	785	13	mRNA	mRNA	NNP
cord-256444-grw5s2pf	785	14	start	start	NN
cord-256444-grw5s2pf	785	15	sites	site	NNS
cord-256444-grw5s2pf	785	16	;	;	:
cord-256444-grw5s2pf	785	17	in	in	IN
cord-256444-grw5s2pf	785	18	the	the	DT
cord-256444-grw5s2pf	785	19	latter	latter	JJ
cord-256444-grw5s2pf	785	20	case	case	NN
cord-256444-grw5s2pf	785	21	,	,	,
cord-256444-grw5s2pf	785	22	sequences	sequence	NNS
cord-256444-grw5s2pf	785	23	in	in	IN
cord-256444-grw5s2pf	785	24	the	the	DT
cord-256444-grw5s2pf	785	25	mature	mature	NN
cord-256444-grw5s2pf	785	26	mRNAs	mrnas	$
cord-256444-grw5s2pf	785	27	usually	usually	RB
cord-256444-grw5s2pf	785	28	match	match	VBP
cord-256444-grw5s2pf	785	29	those	those	DT
cord-256444-grw5s2pf	785	30	of	of	IN
cord-256444-grw5s2pf	785	31	the	the	DT
cord-256444-grw5s2pf	785	32	template	template	NN
cord-256444-grw5s2pf	785	33	instead	instead	RB
cord-256444-grw5s2pf	785	34	of	of	IN
cord-256444-grw5s2pf	785	35	the	the	DT
cord-256444-grw5s2pf	785	36	leader	leader	NN
cord-256444-grw5s2pf	785	37	.	.	.
cord-256444-grw5s2pf	786	1	Therefore	therefore	RB
cord-256444-grw5s2pf	786	2	,	,	,
cord-256444-grw5s2pf	786	3	the	the	DT
cord-256444-grw5s2pf	786	4	free	free	JJ
cord-256444-grw5s2pf	786	5	leader	leader	NN
cord-256444-grw5s2pf	786	6	RNA	RNA	NNP
cord-256444-grw5s2pf	786	7	probably	probably	RB
cord-256444-grw5s2pf	786	8	undergoes	undergo	VBZ
cord-256444-grw5s2pf	786	9	3	3	CD
cord-256444-grw5s2pf	786	10	'	'	NN
cord-256444-grw5s2pf	786	11	end	end	NN
cord-256444-grw5s2pf	786	12	cleavage	cleavage	NN
cord-256444-grw5s2pf	786	13	before	before	IN
cord-256444-grw5s2pf	786	14	transcription	transcription	NN
cord-256444-grw5s2pf	786	15	starts	start	VBZ
cord-256444-grw5s2pf	786	16	to	to	TO
cord-256444-grw5s2pf	786	17	remove	remove	VB
cord-256444-grw5s2pf	786	18	the	the	DT
cord-256444-grw5s2pf	786	19	leader	leader	NN
cord-256444-grw5s2pf	786	20	nucleotides	nucleotide	NNS
cord-256444-grw5s2pf	786	21	that	that	WDT
cord-256444-grw5s2pf	786	22	are	be	VBP
cord-256444-grw5s2pf	786	23	not	not	RB
cord-256444-grw5s2pf	786	24	complementary	complementary	JJ
cord-256444-grw5s2pf	786	25	to	to	IN
cord-256444-grw5s2pf	786	26	the	the	DT
cord-256444-grw5s2pf	786	27	template	template	NN
cord-256444-grw5s2pf	786	28	RNA	RNA	NNP
cord-256444-grw5s2pf	786	29	(	(	-LRB-
cord-256444-grw5s2pf	786	30	Lai	Lai	NNP
cord-256444-grw5s2pf	786	31	,	,	,
cord-256444-grw5s2pf	786	32	1986	1986	CD
cord-256444-grw5s2pf	786	33	(	(	-LRB-
cord-256444-grw5s2pf	786	34	Lai	Lai	NNP
cord-256444-grw5s2pf	786	35	,	,	,
cord-256444-grw5s2pf	786	36	,	,	,
cord-256444-grw5s2pf	786	37	1990	1990	CD
cord-256444-grw5s2pf	786	38	van	van	NNP
cord-256444-grw5s2pf	786	39	der	der	NNP
cord-256444-grw5s2pf	786	40	Most	Most	NNP
cord-256444-grw5s2pf	786	41	et	et	NNP
cord-256444-grw5s2pf	786	42	al	al	NNP
cord-256444-grw5s2pf	786	43	.	.	NNP
cord-256444-grw5s2pf	786	44	,	,	,
cord-256444-grw5s2pf	786	45	1994	1994	CD
cord-256444-grw5s2pf	786	46	)	)	-RRB-
cord-256444-grw5s2pf	786	47	.	.	.
cord-256444-grw5s2pf	787	1	Transcription	transcription	NN
cord-256444-grw5s2pf	787	2	is	be	VBZ
cord-256444-grw5s2pf	787	3	then	then	RB
cord-256444-grw5s2pf	787	4	initiated	initiate	VBN
cord-256444-grw5s2pf	787	5	from	from	IN
cord-256444-grw5s2pf	787	6	the	the	DT
cord-256444-grw5s2pf	787	7	3	3	CD
cord-256444-grw5s2pf	787	8	'	'	NN
cord-256444-grw5s2pf	787	9	end	end	NN
cord-256444-grw5s2pf	787	10	of	of	IN
cord-256444-grw5s2pf	787	11	the	the	DT
cord-256444-grw5s2pf	787	12	processed	process	VBN
cord-256444-grw5s2pf	787	13	leader	leader	NN
cord-256444-grw5s2pf	787	14	RNA	RNA	NNP
cord-256444-grw5s2pf	787	15	.	.	.
cord-256444-grw5s2pf	788	1	This	this	DT
cord-256444-grw5s2pf	788	2	model	model	NN
cord-256444-grw5s2pf	788	3	is	be	VBZ
cord-256444-grw5s2pf	788	4	consistent	consistent	JJ
cord-256444-grw5s2pf	788	5	with	with	IN
cord-256444-grw5s2pf	788	6	most	most	JJS
cord-256444-grw5s2pf	788	7	of	of	IN
cord-256444-grw5s2pf	788	8	the	the	DT
cord-256444-grw5s2pf	788	9	sequence	sequence	NN
cord-256444-grw5s2pf	788	10	data	datum	NNS
cord-256444-grw5s2pf	788	11	of	of	IN
cord-256444-grw5s2pf	788	12	mRNAs	mrnas	CD
cord-256444-grw5s2pf	788	13	.	.	.
cord-256444-grw5s2pf	789	1	It	-PRON-	PRP
cord-256444-grw5s2pf	789	2	also	also	RB
cord-256444-grw5s2pf	789	3	explains	explain	VBZ
cord-256444-grw5s2pf	789	4	the	the	DT
cord-256444-grw5s2pf	789	5	curious	curious	JJ
cord-256444-grw5s2pf	789	6	finding	finding	NN
cord-256444-grw5s2pf	789	7	that	that	IN
cord-256444-grw5s2pf	789	8	some	some	DT
cord-256444-grw5s2pf	789	9	mRNAs	mrnas	CD
cord-256444-grw5s2pf	789	10	of	of	IN
cord-256444-grw5s2pf	789	11	MHV	MHV	NNP
cord-256444-grw5s2pf	789	12	are	be	VBP
cord-256444-grw5s2pf	789	13	heterogeneous	heterogeneous	JJ
cord-256444-grw5s2pf	789	14	in	in	IN
cord-256444-grw5s2pf	789	15	the	the	DT
cord-256444-grw5s2pf	789	16	copy	copy	NN
cord-256444-grw5s2pf	789	17	number	number	NN
cord-256444-grw5s2pf	789	18	(	(	-LRB-
cord-256444-grw5s2pf	789	19	from	from	IN
cord-256444-grw5s2pf	789	20	two	two	CD
cord-256444-grw5s2pf	789	21	to	to	TO
cord-256444-grw5s2pf	789	22	four	four	CD
cord-256444-grw5s2pf	789	23	)	)	-RRB-
cord-256444-grw5s2pf	789	24	of	of	IN
cord-256444-grw5s2pf	789	25	the	the	DT
cord-256444-grw5s2pf	789	26	pentanucleotide	pentanucleotide	NN
cord-256444-grw5s2pf	789	27	(	(	-LRB-
cord-256444-grw5s2pf	789	28	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	789	29	)	)	-RRB-
cord-256444-grw5s2pf	789	30	repeats	repeat	VBZ
cord-256444-grw5s2pf	789	31	at	at	IN
cord-256444-grw5s2pf	789	32	the	the	DT
cord-256444-grw5s2pf	789	33	leader	leader	NN
cord-256444-grw5s2pf	789	34	-	-	HYPH
cord-256444-grw5s2pf	789	35	mRNA	mrna	NN
cord-256444-grw5s2pf	789	36	fusion	fusion	NN
cord-256444-grw5s2pf	789	37	site	site	NN
cord-256444-grw5s2pf	789	38	.	.	.
cord-256444-grw5s2pf	790	1	This	this	DT
cord-256444-grw5s2pf	790	2	heterogeneity	heterogeneity	NN
cord-256444-grw5s2pf	790	3	is	be	VBZ
cord-256444-grw5s2pf	790	4	best	well	RBS
cord-256444-grw5s2pf	790	5	explained	explain	VBN
cord-256444-grw5s2pf	790	6	by	by	IN
cord-256444-grw5s2pf	790	7	the	the	DT
cord-256444-grw5s2pf	790	8	imprecise	imprecise	JJ
cord-256444-grw5s2pf	790	9	binding	binding	NN
cord-256444-grw5s2pf	790	10	between	between	IN
cord-256444-grw5s2pf	790	11	the	the	DT
cord-256444-grw5s2pf	790	12	leader	leader	NN
cord-256444-grw5s2pf	790	13	RNA	RNA	NNP
cord-256444-grw5s2pf	790	14	and	and	CC
cord-256444-grw5s2pf	790	15	template	template	NNP
cord-256444-grw5s2pf	790	16	RNA	RNA	NNP
cord-256444-grw5s2pf	790	17	due	due	IN
cord-256444-grw5s2pf	790	18	to	to	IN
cord-256444-grw5s2pf	790	19	the	the	DT
cord-256444-grw5s2pf	790	20	presence	presence	NN
cord-256444-grw5s2pf	790	21	of	of	IN
cord-256444-grw5s2pf	790	22	multiple	multiple	JJ
cord-256444-grw5s2pf	790	23	copies	copy	NNS
cord-256444-grw5s2pf	790	24	of	of	IN
cord-256444-grw5s2pf	790	25	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	790	26	(	(	-LRB-
cord-256444-grw5s2pf	790	27	Lai	Lai	NNP
cord-256444-grw5s2pf	790	28	,	,	,
cord-256444-grw5s2pf	790	29	1990	1990	CD
cord-256444-grw5s2pf	790	30	)	)	-RRB-
cord-256444-grw5s2pf	790	31	.	.	.
cord-256444-grw5s2pf	791	1	Indeed	indeed	RB
cord-256444-grw5s2pf	791	2	,	,	,
cord-256444-grw5s2pf	791	3	BCV	BCV	NNP
cord-256444-grw5s2pf	791	4	,	,	,
cord-256444-grw5s2pf	791	5	which	which	WDT
cord-256444-grw5s2pf	791	6	contains	contain	VBZ
cord-256444-grw5s2pf	791	7	only	only	RB
cord-256444-grw5s2pf	791	8	one	one	CD
cord-256444-grw5s2pf	791	9	copy	copy	NN
cord-256444-grw5s2pf	791	10	of	of	IN
cord-256444-grw5s2pf	791	11	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	791	12	in	in	IN
cord-256444-grw5s2pf	791	13	both	both	CC
cord-256444-grw5s2pf	791	14	the	the	DT
cord-256444-grw5s2pf	791	15	5	5	CD
cord-256444-grw5s2pf	791	16	'	'	POS
cord-256444-grw5s2pf	791	17	leader	leader	NN
cord-256444-grw5s2pf	791	18	and	and	CC
cord-256444-grw5s2pf	791	19	IG	IG	NNP
cord-256444-grw5s2pf	791	20	sites	site	NNS
cord-256444-grw5s2pf	791	21	,	,	,
cord-256444-grw5s2pf	791	22	does	do	VBZ
cord-256444-grw5s2pf	791	23	not	not	RB
cord-256444-grw5s2pf	791	24	show	show	VB
cord-256444-grw5s2pf	791	25	this	this	DT
cord-256444-grw5s2pf	791	26	type	type	NN
cord-256444-grw5s2pf	791	27	of	of	IN
cord-256444-grw5s2pf	791	28	heterogeneity	heterogeneity	NN
cord-256444-grw5s2pf	791	29	in	in	IN
cord-256444-grw5s2pf	791	30	its	-PRON-	PRP$
cord-256444-grw5s2pf	791	31	mRNAs	mrna	NNS
cord-256444-grw5s2pf	792	1	(	(	-LRB-
cord-256444-grw5s2pf	792	2	Hofmann	Hofmann	NNP
cord-256444-grw5s2pf	792	3	et	et	NNP
cord-256444-grw5s2pf	792	4	al	al	NNP
cord-256444-grw5s2pf	792	5	.	.	NNP
cord-256444-grw5s2pf	792	6	,	,	,
cord-256444-grw5s2pf	792	7	1993a	1993a	CD
cord-256444-grw5s2pf	792	8	)	)	-RRB-
cord-256444-grw5s2pf	792	9	.	.	.
cord-256444-grw5s2pf	793	1	Some	some	DT
cord-256444-grw5s2pf	793	2	recent	recent	JJ
cord-256444-grw5s2pf	793	3	data	datum	NNS
cord-256444-grw5s2pf	793	4	,	,	,
cord-256444-grw5s2pf	793	5	however	however	RB
cord-256444-grw5s2pf	793	6	,	,	,
cord-256444-grw5s2pf	793	7	can	can	MD
cord-256444-grw5s2pf	793	8	not	not	RB
cord-256444-grw5s2pf	793	9	be	be	VB
cord-256444-grw5s2pf	793	10	explained	explain	VBN
cord-256444-grw5s2pf	793	11	by	by	IN
cord-256444-grw5s2pf	793	12	this	this	DT
cord-256444-grw5s2pf	793	13	RNA	RNA	NNP
cord-256444-grw5s2pf	793	14	sequence	sequence	NN
cord-256444-grw5s2pf	793	15	-	-	HYPH
cord-256444-grw5s2pf	793	16	homology	homology	NN
cord-256444-grw5s2pf	793	17	-	-	HYPH
cord-256444-grw5s2pf	793	18	driven	drive	VBN
cord-256444-grw5s2pf	793	19	transcription	transcription	NN
cord-256444-grw5s2pf	793	20	model	model	NN
cord-256444-grw5s2pf	793	21	.	.	.
cord-256444-grw5s2pf	794	1	A	a	DT
cord-256444-grw5s2pf	794	2	particular	particular	JJ
cord-256444-grw5s2pf	794	3	MHV	MHV	NNP
cord-256444-grw5s2pf	794	4	strain	strain	NN
cord-256444-grw5s2pf	794	5	(	(	-LRB-
cord-256444-grw5s2pf	794	6	MHV	MHV	NNP
cord-256444-grw5s2pf	794	7	-	-	HYPH
cord-256444-grw5s2pf	794	8	BC	BC	NNP
cord-256444-grw5s2pf	794	9	)	)	-RRB-
cord-256444-grw5s2pf	794	10	,	,	,
cord-256444-grw5s2pf	794	11	which	which	WDT
cord-256444-grw5s2pf	794	12	has	have	VBZ
cord-256444-grw5s2pf	794	13	four	four	CD
cord-256444-grw5s2pf	794	14	copies	copy	NNS
cord-256444-grw5s2pf	794	15	of	of	IN
cord-256444-grw5s2pf	794	16	the	the	DT
cord-256444-grw5s2pf	794	17	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	794	18	in	in	IN
cord-256444-grw5s2pf	794	19	the	the	DT
cord-256444-grw5s2pf	794	20	leader	leader	NN
cord-256444-grw5s2pf	794	21	RNA	RNA	NNP
cord-256444-grw5s2pf	794	22	,	,	,
cord-256444-grw5s2pf	794	23	synthesizes	synthesize	VBZ
cord-256444-grw5s2pf	794	24	some	some	DT
cord-256444-grw5s2pf	794	25	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	794	26	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	794	27	that	that	WDT
cord-256444-grw5s2pf	794	28	are	be	VBP
cord-256444-grw5s2pf	794	29	very	very	RB
cord-256444-grw5s2pf	794	30	heterogeneous	heterogeneous	JJ
cord-256444-grw5s2pf	794	31	in	in	IN
cord-256444-grw5s2pf	794	32	length	length	NN
cord-256444-grw5s2pf	794	33	and	and	CC
cord-256444-grw5s2pf	794	34	in	in	IN
cord-256444-grw5s2pf	794	35	leader	leader	NN
cord-256444-grw5s2pf	794	36	-	-	HYPH
cord-256444-grw5s2pf	794	37	mRNA	mrna	NN
cord-256444-grw5s2pf	794	38	fusion	fusion	NN
cord-256444-grw5s2pf	794	39	sites	site	NNS
cord-256444-grw5s2pf	794	40	.	.	.
cord-256444-grw5s2pf	795	1	The	the	DT
cord-256444-grw5s2pf	795	2	sequence	sequence	NN
cord-256444-grw5s2pf	795	3	data	datum	NNS
cord-256444-grw5s2pf	795	4	of	of	IN
cord-256444-grw5s2pf	795	5	its	-PRON-	PRP$
cord-256444-grw5s2pf	795	6	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	795	7	showed	show	VBD
cord-256444-grw5s2pf	795	8	that	that	IN
cord-256444-grw5s2pf	795	9	the	the	DT
cord-256444-grw5s2pf	795	10	leader	leader	NN
cord-256444-grw5s2pf	795	11	RNA	RNA	NNP
cord-256444-grw5s2pf	795	12	of	of	IN
cord-256444-grw5s2pf	795	13	this	this	DT
cord-256444-grw5s2pf	795	14	virus	virus	NN
cord-256444-grw5s2pf	795	15	is	be	VBZ
cord-256444-grw5s2pf	795	16	randomly	randomly	RB
cord-256444-grw5s2pf	795	17	fused	fuse	VBN
cord-256444-grw5s2pf	795	18	to	to	IN
cord-256444-grw5s2pf	795	19	sites	site	NNS
cord-256444-grw5s2pf	795	20	where	where	WRB
cord-256444-grw5s2pf	795	21	no	no	DT
cord-256444-grw5s2pf	795	22	sequence	sequence	NN
cord-256444-grw5s2pf	795	23	homology	homology	NN
cord-256444-grw5s2pf	795	24	exists	exist	VBZ
cord-256444-grw5s2pf	795	25	between	between	IN
cord-256444-grw5s2pf	795	26	the	the	DT
cord-256444-grw5s2pf	795	27	leader	leader	NN
cord-256444-grw5s2pf	795	28	and	and	CC
cord-256444-grw5s2pf	795	29	fusion	fusion	NN
cord-256444-grw5s2pf	795	30	sites	site	NNS
cord-256444-grw5s2pf	795	31	(	(	-LRB-
cord-256444-grw5s2pf	795	32	Zhang	Zhang	NNP
cord-256444-grw5s2pf	795	33	et	et	NNP
cord-256444-grw5s2pf	795	34	al	al	NNP
cord-256444-grw5s2pf	795	35	.	.	NNP
cord-256444-grw5s2pf	795	36	,	,	,
cord-256444-grw5s2pf	795	37	199413	199413	CD
cord-256444-grw5s2pf	795	38	)	)	-RRB-
cord-256444-grw5s2pf	795	39	.	.	.
cord-256444-grw5s2pf	796	1	A	a	DT
cord-256444-grw5s2pf	796	2	similar	similar	JJ
cord-256444-grw5s2pf	796	3	though	though	IN
cord-256444-grw5s2pf	796	4	less	less	RBR
cord-256444-grw5s2pf	796	5	conspicuous	conspicuous	JJ
cord-256444-grw5s2pf	796	6	heterogeneity	heterogeneity	NN
cord-256444-grw5s2pf	796	7	in	in	IN
cord-256444-grw5s2pf	796	8	the	the	DT
cord-256444-grw5s2pf	796	9	leader	leader	NN
cord-256444-grw5s2pf	796	10	-	-	HYPH
cord-256444-grw5s2pf	796	11	mRNA	mrna	NN
cord-256444-grw5s2pf	796	12	fusion	fusion	NN
cord-256444-grw5s2pf	796	13	sites	site	NNS
cord-256444-grw5s2pf	796	14	has	have	VBZ
cord-256444-grw5s2pf	796	15	also	also	RB
cord-256444-grw5s2pf	796	16	been	be	VBN
cord-256444-grw5s2pf	796	17	observed	observe	VBN
cord-256444-grw5s2pf	796	18	in	in	IN
cord-256444-grw5s2pf	796	19	another	another	DT
cord-256444-grw5s2pf	796	20	MHV	MHV	NNP
cord-256444-grw5s2pf	796	21	strain	strain	NN
cord-256444-grw5s2pf	796	22	in	in	IN
cord-256444-grw5s2pf	796	23	a	a	DT
cord-256444-grw5s2pf	796	24	DI	DI	NNP
cord-256444-grw5s2pf	796	25	RNA	RNA	NNP
cord-256444-grw5s2pf	796	26	-	-	HYPH
cord-256444-grw5s2pf	796	27	based	base	VBN
cord-256444-grw5s2pf	796	28	transcription	transcription	NN
cord-256444-grw5s2pf	796	29	system	system	NN
cord-256444-grw5s2pf	796	30	(	(	-LRB-
cord-256444-grw5s2pf	796	31	see	see	VB
cord-256444-grw5s2pf	796	32	Section	section	NN
cord-256444-grw5s2pf	796	33	V	v	NN
cord-256444-grw5s2pf	796	34	,	,	,
cord-256444-grw5s2pf	796	35	E,5	E,5	NNP
cord-256444-grw5s2pf	796	36	)	)	-RRB-
cord-256444-grw5s2pf	797	1	(	(	-LRB-
cord-256444-grw5s2pf	797	2	van	van	NNP
cord-256444-grw5s2pf	797	3	der	der	NNP
cord-256444-grw5s2pf	797	4	Most	Most	NNP
cord-256444-grw5s2pf	797	5	et	et	NNP
cord-256444-grw5s2pf	797	6	al	al	NNP
cord-256444-grw5s2pf	797	7	.	.	NNP
cord-256444-grw5s2pf	797	8	,	,	,
cord-256444-grw5s2pf	797	9	1994	1994	CD
cord-256444-grw5s2pf	797	10	)	)	-RRB-
cord-256444-grw5s2pf	797	11	.	.	.
cord-256444-grw5s2pf	798	1	These	these	DT
cord-256444-grw5s2pf	798	2	findings	finding	NNS
cord-256444-grw5s2pf	798	3	suggest	suggest	VBP
cord-256444-grw5s2pf	798	4	that	that	IN
cord-256444-grw5s2pf	798	5	the	the	DT
cord-256444-grw5s2pf	798	6	sequence	sequence	NN
cord-256444-grw5s2pf	798	7	complementarity	complementarity	NN
cord-256444-grw5s2pf	798	8	between	between	IN
cord-256444-grw5s2pf	798	9	the	the	DT
cord-256444-grw5s2pf	798	10	leader	leader	NN
cord-256444-grw5s2pf	798	11	RNA	RNA	NNP
cord-256444-grw5s2pf	798	12	and	and	CC
cord-256444-grw5s2pf	798	13	IG	IG	NNP
cord-256444-grw5s2pf	798	14	sites	site	NNS
cord-256444-grw5s2pf	798	15	may	may	MD
cord-256444-grw5s2pf	798	16	not	not	RB
cord-256444-grw5s2pf	798	17	be	be	VB
cord-256444-grw5s2pf	798	18	the	the	DT
cord-256444-grw5s2pf	798	19	driving	drive	VBG
cord-256444-grw5s2pf	798	20	force	force	NN
cord-256444-grw5s2pf	798	21	for	for	IN
cord-256444-grw5s2pf	798	22	mRNA	mRNA	NNP
cord-256444-grw5s2pf	798	23	transcription	transcription	NN
cord-256444-grw5s2pf	798	24	.	.	.
cord-256444-grw5s2pf	799	1	Thus	thus	RB
cord-256444-grw5s2pf	799	2	,	,	,
cord-256444-grw5s2pf	799	3	a	a	DT
cord-256444-grw5s2pf	799	4	modified	modify	VBN
cord-256444-grw5s2pf	799	5	version	version	NN
cord-256444-grw5s2pf	799	6	of	of	IN
cord-256444-grw5s2pf	799	7	the	the	DT
cord-256444-grw5s2pf	799	8	leader	leader	NN
cord-256444-grw5s2pf	799	9	-	-	HYPH
cord-256444-grw5s2pf	799	10	primed	prime	VBN
cord-256444-grw5s2pf	799	11	transcription	transcription	NN
cord-256444-grw5s2pf	799	12	model	model	NN
cord-256444-grw5s2pf	799	13	proposes	propose	VBZ
cord-256444-grw5s2pf	799	14	that	that	IN
cord-256444-grw5s2pf	799	15	the	the	DT
cord-256444-grw5s2pf	799	16	UCUAAAC	UCUAAAC	NNP
cord-256444-grw5s2pf	799	17	sequence	sequence	NN
cord-256444-grw5s2pf	799	18	provides	provide	VBZ
cord-256444-grw5s2pf	799	19	a	a	DT
cord-256444-grw5s2pf	799	20	recognition	recognition	NN
cord-256444-grw5s2pf	799	21	signal	signal	NN
cord-256444-grw5s2pf	799	22	for	for	IN
cord-256444-grw5s2pf	799	23	viral	viral	JJ
cord-256444-grw5s2pf	799	24	polymerases	polymerase	NNS
cord-256444-grw5s2pf	799	25	and	and	CC
cord-256444-grw5s2pf	799	26	viral	viral	JJ
cord-256444-grw5s2pf	799	27	or	or	CC
cord-256444-grw5s2pf	799	28	cellular	cellular	JJ
cord-256444-grw5s2pf	799	29	transcription	transcription	NN
cord-256444-grw5s2pf	799	30	factors	factor	NNS
cord-256444-grw5s2pf	799	31	.	.	.
cord-256444-grw5s2pf	800	1	These	these	DT
cord-256444-grw5s2pf	800	2	proteins	protein	NNS
cord-256444-grw5s2pf	800	3	bind	bind	VBP
cord-256444-grw5s2pf	800	4	to	to	IN
cord-256444-grw5s2pf	800	5	the	the	DT
cord-256444-grw5s2pf	800	6	leader	leader	NN
cord-256444-grw5s2pf	800	7	and	and	CC
cord-256444-grw5s2pf	800	8	IG	IG	NNP
cord-256444-grw5s2pf	800	9	sites	site	NNS
cord-256444-grw5s2pf	800	10	of	of	IN
cord-256444-grw5s2pf	800	11	the	the	DT
cord-256444-grw5s2pf	800	12	template	template	NN
cord-256444-grw5s2pf	800	13	RNA	RNA	NNP
cord-256444-grw5s2pf	800	14	,	,	,
cord-256444-grw5s2pf	800	15	and	and	CC
cord-256444-grw5s2pf	800	16	the	the	DT
cord-256444-grw5s2pf	800	17	subsequent	subsequent	JJ
cord-256444-grw5s2pf	800	18	RNA	RNA	NNP
cord-256444-grw5s2pf	800	19	-	-	HYPH
cord-256444-grw5s2pf	800	20	protein	protein	NN
cord-256444-grw5s2pf	800	21	and	and	CC
cord-256444-grw5s2pf	800	22	protein	protein	NN
cord-256444-grw5s2pf	800	23	-	-	HYPH
cord-256444-grw5s2pf	800	24	protein	protein	NN
cord-256444-grw5s2pf	800	25	interactions	interaction	NNS
cord-256444-grw5s2pf	800	26	result	result	VBP
cord-256444-grw5s2pf	800	27	in	in	IN
cord-256444-grw5s2pf	800	28	the	the	DT
cord-256444-grw5s2pf	800	29	formation	formation	NN
cord-256444-grw5s2pf	800	30	of	of	IN
cord-256444-grw5s2pf	800	31	a	a	DT
cord-256444-grw5s2pf	800	32	transcription	transcription	NN
cord-256444-grw5s2pf	800	33	complex	complex	NN
cord-256444-grw5s2pf	800	34	to	to	TO
cord-256444-grw5s2pf	800	35	initiate	initiate	VB
cord-256444-grw5s2pf	800	36	mRNA	mrna	NN
cord-256444-grw5s2pf	800	37	transcription	transcription	NN
cord-256444-grw5s2pf	800	38	and	and	CC
cord-256444-grw5s2pf	800	39	effect	effect	NN
cord-256444-grw5s2pf	800	40	leader	leader	NN
cord-256444-grw5s2pf	800	41	-	-	HYPH
cord-256444-grw5s2pf	800	42	mRNA	mrna	NN
cord-256444-grw5s2pf	800	43	fusion	fusion	NN
cord-256444-grw5s2pf	800	44	Zhang	Zhang	NNP
cord-256444-grw5s2pf	800	45	and	and	CC
cord-256444-grw5s2pf	800	46	Lai	Lai	NNP
cord-256444-grw5s2pf	800	47	,	,	,
cord-256444-grw5s2pf	800	48	1995	1995	CD
cord-256444-grw5s2pf	800	49	)	)	-RRB-
cord-256444-grw5s2pf	800	50	.	.	.
cord-256444-grw5s2pf	801	1	The	the	DT
cord-256444-grw5s2pf	801	2	salient	salient	JJ
cord-256444-grw5s2pf	801	3	feature	feature	NN
cord-256444-grw5s2pf	801	4	of	of	IN
cord-256444-grw5s2pf	801	5	this	this	DT
cord-256444-grw5s2pf	801	6	model	model	NN
cord-256444-grw5s2pf	801	7	is	be	VBZ
cord-256444-grw5s2pf	801	8	that	that	IN
cord-256444-grw5s2pf	801	9	the	the	DT
cord-256444-grw5s2pf	801	10	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	801	11	transcription	transcription	NN
cord-256444-grw5s2pf	801	12	step	step	NN
cord-256444-grw5s2pf	801	13	occurs	occur	VBZ
cord-256444-grw5s2pf	801	14	during	during	IN
cord-256444-grw5s2pf	801	15	positive	positive	JJ
cord-256444-grw5s2pf	801	16	-	-	HYPH
cord-256444-grw5s2pf	801	17	strand	strand	NN
cord-256444-grw5s2pf	801	18	RNA	RNA	NNP
cord-256444-grw5s2pf	801	19	synthesis	synthesis	NN
cord-256444-grw5s2pf	801	20	;	;	:
cord-256444-grw5s2pf	801	21	thus	thus	RB
cord-256444-grw5s2pf	801	22	,	,	,
cord-256444-grw5s2pf	801	23	transcriptional	transcriptional	JJ
cord-256444-grw5s2pf	801	24	regulation	regulation	NN
cord-256444-grw5s2pf	801	25	is	be	VBZ
cord-256444-grw5s2pf	801	26	exerted	exert	VBN
cord-256444-grw5s2pf	801	27	mainly	mainly	RB
cord-256444-grw5s2pf	801	28	during	during	IN
cord-256444-grw5s2pf	801	29	positive	positive	JJ
cord-256444-grw5s2pf	801	30	-	-	HYPH
cord-256444-grw5s2pf	801	31	strand	strand	NN
cord-256444-grw5s2pf	801	32	RNA	RNA	NNP
cord-256444-grw5s2pf	801	33	synthesis	synthesis	NN
cord-256444-grw5s2pf	801	34	.	.	.
cord-256444-grw5s2pf	802	1	This	this	DT
cord-256444-grw5s2pf	802	2	is	be	VBZ
cord-256444-grw5s2pf	802	3	consistent	consistent	JJ
cord-256444-grw5s2pf	802	4	with	with	IN
cord-256444-grw5s2pf	802	5	current	current	JJ
cord-256444-grw5s2pf	802	6	knowledge	knowledge	NN
cord-256444-grw5s2pf	802	7	of	of	IN
cord-256444-grw5s2pf	802	8	the	the	DT
cord-256444-grw5s2pf	802	9	regulation	regulation	NN
cord-256444-grw5s2pf	802	10	of	of	IN
cord-256444-grw5s2pf	802	11	MHV	MHV	NNP
cord-256444-grw5s2pf	802	12	RNA	RNA	NNP
cord-256444-grw5s2pf	802	13	synthesis	synthesis	NN
cord-256444-grw5s2pf	802	14	.	.	.
cord-256444-grw5s2pf	803	1	It	-PRON-	PRP
cord-256444-grw5s2pf	803	2	has	have	VBZ
cord-256444-grw5s2pf	803	3	been	be	VBN
cord-256444-grw5s2pf	803	4	shown	show	VBN
cord-256444-grw5s2pf	803	5	that	that	IN
cord-256444-grw5s2pf	803	6	MHV	MHV	NNP
cord-256444-grw5s2pf	803	7	mRNA	mrna	NN
cord-256444-grw5s2pf	803	8	transcription	transcription	NN
cord-256444-grw5s2pf	803	9	requires	require	VBZ
cord-256444-grw5s2pf	803	10	multiple	multiple	JJ
cord-256444-grw5s2pf	803	11	cis	cis	NNP
cord-256444-grw5s2pf	803	12	-	-	HYPH
cord-256444-grw5s2pf	803	13	acting	act	VBG
cord-256444-grw5s2pf	803	14	RNA	RNA	NNP
cord-256444-grw5s2pf	803	15	sequences	sequence	NNS
cord-256444-grw5s2pf	803	16	(	(	-LRB-
cord-256444-grw5s2pf	803	17	see	see	VB
cord-256444-grw5s2pf	803	18	Section	section	NN
cord-256444-grw5s2pf	803	19	V	v	NN
cord-256444-grw5s2pf	803	20	,	,	,
cord-256444-grw5s2pf	803	21	E,5	E,5	NNP
cord-256444-grw5s2pf	803	22	)	)	-RRB-
cord-256444-grw5s2pf	803	23	.	.	.
cord-256444-grw5s2pf	804	1	In	in	IN
cord-256444-grw5s2pf	804	2	contrast	contrast	NN
cord-256444-grw5s2pf	804	3	,	,	,
cord-256444-grw5s2pf	804	4	the	the	DT
cord-256444-grw5s2pf	804	5	initiation	initiation	NN
cord-256444-grw5s2pf	804	6	of	of	IN
cord-256444-grw5s2pf	804	7	negative	negative	JJ
cord-256444-grw5s2pf	804	8	-	-	HYPH
cord-256444-grw5s2pf	804	9	strand	strand	NN
cord-256444-grw5s2pf	804	10	RNA	RNA	NNP
cord-256444-grw5s2pf	804	11	synthesis	synthesis	NN
cord-256444-grw5s2pf	804	12	requires	require	VBZ
cord-256444-grw5s2pf	804	13	only	only	RB
cord-256444-grw5s2pf	804	14	the	the	DT
cord-256444-grw5s2pf	804	15	3	3	CD
cord-256444-grw5s2pf	804	16	'	'	''
cord-256444-grw5s2pf	804	17	end	end	NN
cord-256444-grw5s2pf	804	18	55-nt	55-nt	CD
cord-256444-grw5s2pf	804	19	plus	plus	CC
cord-256444-grw5s2pf	804	20	poly(A	poly(A	NNP
cord-256444-grw5s2pf	804	21	)	)	-RRB-
cord-256444-grw5s2pf	804	22	.	.	.
cord-256444-grw5s2pf	805	1	Thus	thus	RB
cord-256444-grw5s2pf	805	2	,	,	,
cord-256444-grw5s2pf	805	3	most	most	JJS
cord-256444-grw5s2pf	805	4	of	of	IN
cord-256444-grw5s2pf	805	5	the	the	DT
cord-256444-grw5s2pf	805	6	regulatory	regulatory	JJ
cord-256444-grw5s2pf	805	7	elements	element	NNS
cord-256444-grw5s2pf	805	8	appear	appear	VBP
cord-256444-grw5s2pf	805	9	to	to	TO
cord-256444-grw5s2pf	805	10	regulate	regulate	VB
cord-256444-grw5s2pf	805	11	positive	positive	JJ
cord-256444-grw5s2pf	805	12	-	-	HYPH
cord-256444-grw5s2pf	805	13	strand	strand	NN
cord-256444-grw5s2pf	805	14	RNA	RNA	NNP
cord-256444-grw5s2pf	805	15	synthesis	synthesis	NN
cord-256444-grw5s2pf	805	16	.	.	.
cord-256444-grw5s2pf	806	1	Since	since	IN
cord-256444-grw5s2pf	806	2	the	the	DT
cord-256444-grw5s2pf	806	3	free	free	JJ
cord-256444-grw5s2pf	806	4	leader	leader	NN
cord-256444-grw5s2pf	806	5	RNA	RNA	NNP
cord-256444-grw5s2pf	806	6	is	be	VBZ
cord-256444-grw5s2pf	806	7	the	the	DT
cord-256444-grw5s2pf	806	8	centerpiece	centerpiece	NN
cord-256444-grw5s2pf	806	9	of	of	IN
cord-256444-grw5s2pf	806	10	this	this	DT
cord-256444-grw5s2pf	806	11	transcription	transcription	NN
cord-256444-grw5s2pf	806	12	model	model	NN
cord-256444-grw5s2pf	806	13	,	,	,
cord-256444-grw5s2pf	806	14	it	-PRON-	PRP
cord-256444-grw5s2pf	806	15	readily	readily	RB
cord-256444-grw5s2pf	806	16	explains	explain	VBZ
cord-256444-grw5s2pf	806	17	why	why	WRB
cord-256444-grw5s2pf	806	18	the	the	DT
cord-256444-grw5s2pf	806	19	leader	leader	NN
cord-256444-grw5s2pf	806	20	RNA	RNA	NNP
cord-256444-grw5s2pf	806	21	from	from	IN
cord-256444-grw5s2pf	806	22	a	a	DT
cord-256444-grw5s2pf	806	23	different	different	JJ
cord-256444-grw5s2pf	806	24	virus	virus	NN
cord-256444-grw5s2pf	806	25	can	can	MD
cord-256444-grw5s2pf	806	26	be	be	VB
cord-256444-grw5s2pf	806	27	utilized	utilize	VBN
cord-256444-grw5s2pf	806	28	freely	freely	RB
cord-256444-grw5s2pf	806	29	in	in	IN
cord-256444-grw5s2pf	806	30	trans	trans	NNP
cord-256444-grw5s2pf	806	31	during	during	IN
cord-256444-grw5s2pf	806	32	mixed	mixed	JJ
cord-256444-grw5s2pf	806	33	infections	infection	NNS
cord-256444-grw5s2pf	807	1	(	(	-LRB-
cord-256444-grw5s2pf	807	2	Makino	Makino	NNP
cord-256444-grw5s2pf	807	3	et	et	NNP
cord-256444-grw5s2pf	807	4	al	al	NNP
cord-256444-grw5s2pf	807	5	.	.	NNP
cord-256444-grw5s2pf	807	6	,	,	,
cord-256444-grw5s2pf	807	7	1986b	1986b	CD
cord-256444-grw5s2pf	807	8	)	)	-RRB-
cord-256444-grw5s2pf	807	9	.	.	.
cord-256444-grw5s2pf	808	1	However	however	RB
cord-256444-grw5s2pf	808	2	,	,	,
cord-256444-grw5s2pf	808	3	this	this	DT
cord-256444-grw5s2pf	808	4	model	model	NN
cord-256444-grw5s2pf	808	5	does	do	VBZ
cord-256444-grw5s2pf	808	6	not	not	RB
cord-256444-grw5s2pf	808	7	explain	explain	VB
cord-256444-grw5s2pf	808	8	the	the	DT
cord-256444-grw5s2pf	808	9	finding	finding	NN
cord-256444-grw5s2pf	808	10	that	that	IN
cord-256444-grw5s2pf	808	11	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	808	12	replicative	replicative	JJ
cord-256444-grw5s2pf	808	13	-	-	:
cord-256444-grw5s2pf	808	14	intermediates	intermediate	NNS
cord-256444-grw5s2pf	808	15	(	(	-LRB-
cord-256444-grw5s2pf	808	16	RI	RI	NNP
cord-256444-grw5s2pf	808	17	)	)	-RRB-
cord-256444-grw5s2pf	808	18	and	and	CC
cord-256444-grw5s2pf	808	19	replicative	replicative	JJ
cord-256444-grw5s2pf	808	20	-	-	HYPH
cord-256444-grw5s2pf	808	21	form	form	NN
cord-256444-grw5s2pf	808	22	(	(	-LRB-
cord-256444-grw5s2pf	808	23	RF	rf	NN
cord-256444-grw5s2pf	808	24	)	)	-RRB-
cord-256444-grw5s2pf	808	25	RNAs	rna	NNS
cord-256444-grw5s2pf	808	26	were	be	VBD
cord-256444-grw5s2pf	808	27	detected	detect	VBN
cord-256444-grw5s2pf	808	28	and	and	CC
cord-256444-grw5s2pf	808	29	were	be	VBD
cord-256444-grw5s2pf	808	30	functional	functional	JJ
cord-256444-grw5s2pf	808	31	during	during	IN
cord-256444-grw5s2pf	808	32	viral	viral	JJ
cord-256444-grw5s2pf	808	33	RNA	RNA	NNP
cord-256444-grw5s2pf	808	34	synthesis	synthesis	NN
cord-256444-grw5s2pf	808	35	(	(	-LRB-
cord-256444-grw5s2pf	808	36	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	808	37	and	and	CC
cord-256444-grw5s2pf	808	38	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	808	39	,	,	,
cord-256444-grw5s2pf	808	40	1990	1990	CD
cord-256444-grw5s2pf	808	41	;	;	:
cord-256444-grw5s2pf	808	42	Schaad	Schaad	NNP
cord-256444-grw5s2pf	808	43	and	and	CC
cord-256444-grw5s2pf	808	44	Baric	Baric	NNP
cord-256444-grw5s2pf	808	45	,	,	,
cord-256444-grw5s2pf	808	46	1994	1994	CD
cord-256444-grw5s2pf	808	47	)	)	-RRB-
cord-256444-grw5s2pf	808	48	(	(	-LRB-
cord-256444-grw5s2pf	808	49	see	see	VB
cord-256444-grw5s2pf	808	50	Section	section	NN
cord-256444-grw5s2pf	808	51	V	v	NN
cord-256444-grw5s2pf	808	52	,	,	,
cord-256444-grw5s2pf	808	53	E,4,b	E,4,b	''
cord-256444-grw5s2pf	808	54	)	)	-RRB-
cord-256444-grw5s2pf	808	55	.	.	.
cord-256444-grw5s2pf	809	1	It	-PRON-	PRP
cord-256444-grw5s2pf	809	2	is	be	VBZ
cord-256444-grw5s2pf	809	3	possible	possible	JJ
cord-256444-grw5s2pf	809	4	that	that	IN
cord-256444-grw5s2pf	809	5	the	the	DT
cord-256444-grw5s2pf	809	6	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	809	7	mRNAs	mrnas	XX
cord-256444-grw5s2pf	809	8	synthesized	synthesize	VBN
cord-256444-grw5s2pf	809	9	can	can	MD
cord-256444-grw5s2pf	809	10	be	be	VB
cord-256444-grw5s2pf	809	11	transcribed	transcribe	VBN
cord-256444-grw5s2pf	809	12	into	into	IN
cord-256444-grw5s2pf	809	13	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	809	14	negative	negative	JJ
cord-256444-grw5s2pf	809	15	-	-	HYPH
cord-256444-grw5s2pf	809	16	strand	strand	NN
cord-256444-grw5s2pf	809	17	RNAs	rna	NNS
cord-256444-grw5s2pf	809	18	,	,	,
cord-256444-grw5s2pf	809	19	which	which	WDT
cord-256444-grw5s2pf	809	20	,	,	,
cord-256444-grw5s2pf	809	21	in	in	IN
cord-256444-grw5s2pf	809	22	turn	turn	NN
cord-256444-grw5s2pf	809	23	,	,	,
cord-256444-grw5s2pf	809	24	become	become	VB
cord-256444-grw5s2pf	809	25	the	the	DT
cord-256444-grw5s2pf	809	26	templates	template	NNS
cord-256444-grw5s2pf	809	27	for	for	IN
cord-256444-grw5s2pf	809	28	mRNA	mrna	NN
cord-256444-grw5s2pf	809	29	transcription	transcription	NN
cord-256444-grw5s2pf	809	30	at	at	IN
cord-256444-grw5s2pf	809	31	a	a	DT
cord-256444-grw5s2pf	809	32	later	later	JJ
cord-256444-grw5s2pf	809	33	stage	stage	NN
cord-256444-grw5s2pf	809	34	in	in	IN
cord-256444-grw5s2pf	809	35	the	the	DT
cord-256444-grw5s2pf	809	36	viral	viral	JJ
cord-256444-grw5s2pf	809	37	replication	replication	NN
cord-256444-grw5s2pf	809	38	cycle	cycle	NN
cord-256444-grw5s2pf	809	39	.	.	.
cord-256444-grw5s2pf	810	1	This	this	DT
cord-256444-grw5s2pf	810	2	would	would	MD
cord-256444-grw5s2pf	810	3	explain	explain	VB
cord-256444-grw5s2pf	810	4	why	why	WRB
cord-256444-grw5s2pf	810	5	the	the	DT
cord-256444-grw5s2pf	810	6	UV	uv	NN
cord-256444-grw5s2pf	810	7	target	target	NN
cord-256444-grw5s2pf	810	8	sizes	size	NNS
cord-256444-grw5s2pf	810	9	for	for	IN
cord-256444-grw5s2pf	810	10	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	810	11	are	be	VBP
cord-256444-grw5s2pf	810	12	nearly	nearly	RB
cord-256444-grw5s2pf	810	13	equivalent	equivalent	JJ
cord-256444-grw5s2pf	810	14	to	to	IN
cord-256444-grw5s2pf	810	15	the	the	DT
cord-256444-grw5s2pf	810	16	physical	physical	JJ
cord-256444-grw5s2pf	810	17	sizes	size	NNS
cord-256444-grw5s2pf	810	18	of	of	IN
cord-256444-grw5s2pf	810	19	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	810	20	late	late	RB
cord-256444-grw5s2pf	810	21	in	in	IN
cord-256444-grw5s2pf	810	22	the	the	DT
cord-256444-grw5s2pf	810	23	infection	infection	NN
cord-256444-grw5s2pf	810	24	and	and	CC
cord-256444-grw5s2pf	810	25	yet	yet	RB
cord-256444-grw5s2pf	810	26	are	be	VBP
cord-256444-grw5s2pf	810	27	equivalent	equivalent	JJ
cord-256444-grw5s2pf	810	28	to	to	IN
cord-256444-grw5s2pf	810	29	the	the	DT
cord-256444-grw5s2pf	810	30	genomic	genomic	JJ
cord-256444-grw5s2pf	810	31	-	-	HYPH
cord-256444-grw5s2pf	810	32	sized	sized	JJ
cord-256444-grw5s2pf	810	33	RNA	RNA	NNP
cord-256444-grw5s2pf	810	34	early	early	RB
cord-256444-grw5s2pf	810	35	in	in	IN
cord-256444-grw5s2pf	810	36	the	the	DT
cord-256444-grw5s2pf	810	37	infection	infection	NN
cord-256444-grw5s2pf	811	1	(	(	-LRB-
cord-256444-grw5s2pf	811	2	Yokomori	Yokomori	NNP
cord-256444-grw5s2pf	811	3	et	et	FW
cord-256444-grw5s2pf	811	4	al	al	NNP
cord-256444-grw5s2pf	811	5	.	.	NNP
cord-256444-grw5s2pf	811	6	,	,	,
cord-256444-grw5s2pf	811	7	1992b	1992b	CD
cord-256444-grw5s2pf	811	8	)	)	-RRB-
cord-256444-grw5s2pf	811	9	.	.	.
cord-256444-grw5s2pf	812	1	In	in	IN
cord-256444-grw5s2pf	812	2	contrast	contrast	NN
cord-256444-grw5s2pf	812	3	to	to	IN
cord-256444-grw5s2pf	812	4	the	the	DT
cord-256444-grw5s2pf	812	5	leader	leader	NN
cord-256444-grw5s2pf	812	6	-	-	HYPH
cord-256444-grw5s2pf	812	7	primed	prime	VBN
cord-256444-grw5s2pf	812	8	transcription	transcription	NN
cord-256444-grw5s2pf	812	9	model	model	NN
cord-256444-grw5s2pf	812	10	,	,	,
cord-256444-grw5s2pf	812	11	this	this	DT
cord-256444-grw5s2pf	812	12	model	model	NN
cord-256444-grw5s2pf	812	13	proposes	propose	VBZ
cord-256444-grw5s2pf	812	14	that	that	IN
cord-256444-grw5s2pf	812	15	the	the	DT
cord-256444-grw5s2pf	812	16	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	812	17	transcription	transcription	NN
cord-256444-grw5s2pf	812	18	step	step	NN
cord-256444-grw5s2pf	812	19	occurs	occur	VBZ
cord-256444-grw5s2pf	812	20	during	during	IN
cord-256444-grw5s2pf	812	21	negative	negative	JJ
cord-256444-grw5s2pf	812	22	-	-	HYPH
cord-256444-grw5s2pf	812	23	strand	strand	NN
cord-256444-grw5s2pf	812	24	RNA	RNA	NNP
cord-256444-grw5s2pf	812	25	synthesis	synthesis	NN
cord-256444-grw5s2pf	812	26	,	,	,
cord-256444-grw5s2pf	812	27	generating	generate	VBG
cord-256444-grw5s2pf	812	28	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	812	29	negativestrand	negativestrand	NNP
cord-256444-grw5s2pf	812	30	RNAs	RNAs	NNPS
cord-256444-grw5s2pf	812	31	,	,	,
cord-256444-grw5s2pf	812	32	which	which	WDT
cord-256444-grw5s2pf	812	33	then	then	RB
cord-256444-grw5s2pf	812	34	serve	serve	VBP
cord-256444-grw5s2pf	812	35	as	as	IN
cord-256444-grw5s2pf	812	36	templates	template	NNS
cord-256444-grw5s2pf	812	37	for	for	IN
cord-256444-grw5s2pf	812	38	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	812	39	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	812	40	in	in	IN
cord-256444-grw5s2pf	812	41	uninterrupted	uninterrupted	JJ
cord-256444-grw5s2pf	812	42	transcription	transcription	NN
cord-256444-grw5s2pf	812	43	.	.	.
cord-256444-grw5s2pf	813	1	This	this	DT
cord-256444-grw5s2pf	813	2	model	model	NN
cord-256444-grw5s2pf	813	3	was	be	VBD
cord-256444-grw5s2pf	813	4	proposed	propose	VBN
cord-256444-grw5s2pf	813	5	to	to	TO
cord-256444-grw5s2pf	813	6	account	account	VB
cord-256444-grw5s2pf	813	7	for	for	IN
cord-256444-grw5s2pf	813	8	the	the	DT
cord-256444-grw5s2pf	813	9	detection	detection	NN
cord-256444-grw5s2pf	813	10	of	of	IN
cord-256444-grw5s2pf	813	11	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	813	12	negative	negative	JJ
cord-256444-grw5s2pf	813	13	-	-	HYPH
cord-256444-grw5s2pf	813	14	strand	strand	NN
cord-256444-grw5s2pf	813	15	RNAs	rna	NNS
cord-256444-grw5s2pf	813	16	(	(	-LRB-
cord-256444-grw5s2pf	813	17	Sethna	Sethna	NNP
cord-256444-grw5s2pf	813	18	et	et	NNP
cord-256444-grw5s2pf	813	19	al	al	NNP
cord-256444-grw5s2pf	813	20	.	.	NNP
cord-256444-grw5s2pf	813	21	,	,	,
cord-256444-grw5s2pf	813	22	1989	1989	CD
cord-256444-grw5s2pf	813	23	;	;	:
cord-256444-grw5s2pf	813	24	Hofmann	Hofmann	NNP
cord-256444-grw5s2pf	813	25	et	et	NNP
cord-256444-grw5s2pf	813	26	al	al	NNP
cord-256444-grw5s2pf	813	27	.	.	NNP
cord-256444-grw5s2pf	813	28	,	,	,
cord-256444-grw5s2pf	813	29	1990	1990	CD
cord-256444-grw5s2pf	813	30	)	)	-RRB-
cord-256444-grw5s2pf	813	31	and	and	CC
cord-256444-grw5s2pf	813	32	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	813	33	RIs	RIs	NNP
cord-256444-grw5s2pf	813	34	(	(	-LRB-
cord-256444-grw5s2pf	813	35	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	813	36	and	and	CC
cord-256444-grw5s2pf	813	37	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	813	38	,	,	,
cord-256444-grw5s2pf	813	39	1990	1990	CD
cord-256444-grw5s2pf	813	40	)	)	-RRB-
cord-256444-grw5s2pf	813	41	in	in	IN
cord-256444-grw5s2pf	813	42	virus	virus	NN
cord-256444-grw5s2pf	813	43	-	-	HYPH
cord-256444-grw5s2pf	813	44	infected	infect	VBN
cord-256444-grw5s2pf	813	45	cells	cell	NNS
cord-256444-grw5s2pf	813	46	.	.	.
cord-256444-grw5s2pf	814	1	In	in	IN
cord-256444-grw5s2pf	814	2	this	this	DT
cord-256444-grw5s2pf	814	3	model	model	NN
cord-256444-grw5s2pf	814	4	,	,	,
cord-256444-grw5s2pf	814	5	IG	IG	NNP
cord-256444-grw5s2pf	814	6	(	(	-LRB-
cord-256444-grw5s2pf	814	7	mRNA	mrna	NN
cord-256444-grw5s2pf	814	8	start	start	NN
cord-256444-grw5s2pf	814	9	site	site	NN
cord-256444-grw5s2pf	814	10	)	)	-RRB-
cord-256444-grw5s2pf	814	11	sequences	sequence	NNS
cord-256444-grw5s2pf	814	12	on	on	IN
cord-256444-grw5s2pf	814	13	the	the	DT
cord-256444-grw5s2pf	814	14	genomic	genomic	JJ
cord-256444-grw5s2pf	814	15	RNA	RNA	NNP
cord-256444-grw5s2pf	814	16	serve	serve	VBP
cord-256444-grw5s2pf	814	17	as	as	IN
cord-256444-grw5s2pf	814	18	termination	termination	NN
cord-256444-grw5s2pf	814	19	or	or	CC
cord-256444-grw5s2pf	814	20	pausing	pause	VBG
cord-256444-grw5s2pf	814	21	signals	signal	NNS
cord-256444-grw5s2pf	814	22	for	for	IN
cord-256444-grw5s2pf	814	23	negative	negative	JJ
cord-256444-grw5s2pf	814	24	-	-	HYPH
cord-256444-grw5s2pf	814	25	strand	strand	NN
cord-256444-grw5s2pf	814	26	synthesis	synthesis	NN
cord-256444-grw5s2pf	815	1	(	(	-LRB-
cord-256444-grw5s2pf	815	2	Konings	Konings	NNP
cord-256444-grw5s2pf	815	3	et	et	FW
cord-256444-grw5s2pf	815	4	al	al	NNP
cord-256444-grw5s2pf	815	5	.	.	NNP
cord-256444-grw5s2pf	815	6	,	,	,
cord-256444-grw5s2pf	815	7	19881	19881	CD
cord-256444-grw5s2pf	815	8	,	,	,
cord-256444-grw5s2pf	815	9	and	and	CC
cord-256444-grw5s2pf	815	10	the	the	DT
cord-256444-grw5s2pf	815	11	nascent	nascent	JJ
cord-256444-grw5s2pf	815	12	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	815	13	negative	negative	JJ
cord-256444-grw5s2pf	815	14	-	-	HYPH
cord-256444-grw5s2pf	815	15	strand	strand	NN
cord-256444-grw5s2pf	815	16	RNA	RNA	NNP
cord-256444-grw5s2pf	815	17	then	then	RB
cord-256444-grw5s2pf	815	18	jumps	jump	VBZ
cord-256444-grw5s2pf	815	19	to	to	IN
cord-256444-grw5s2pf	815	20	the	the	DT
cord-256444-grw5s2pf	815	21	leader	leader	NN
cord-256444-grw5s2pf	815	22	RNA	RNA	NNP
cord-256444-grw5s2pf	815	23	sequence	sequence	NN
cord-256444-grw5s2pf	815	24	at	at	IN
cord-256444-grw5s2pf	815	25	the	the	DT
cord-256444-grw5s2pf	815	26	5	5	CD
cord-256444-grw5s2pf	815	27	'	'	NN
cord-256444-grw5s2pf	815	28	end	end	NN
cord-256444-grw5s2pf	815	29	of	of	IN
cord-256444-grw5s2pf	815	30	the	the	DT
cord-256444-grw5s2pf	815	31	genomic	genomic	JJ
cord-256444-grw5s2pf	815	32	RNA	RNA	NNP
cord-256444-grw5s2pf	815	33	by	by	IN
cord-256444-grw5s2pf	815	34	an	an	DT
cord-256444-grw5s2pf	815	35	unknown	unknown	JJ
cord-256444-grw5s2pf	815	36	mechanism	mechanism	NN
cord-256444-grw5s2pf	815	37	to	to	TO
cord-256444-grw5s2pf	815	38	continue	continue	VB
cord-256444-grw5s2pf	815	39	RNA	RNA	NNP
cord-256444-grw5s2pf	815	40	synthesis	synthesis	NN
cord-256444-grw5s2pf	815	41	.	.	.
cord-256444-grw5s2pf	816	1	As	as	IN
cord-256444-grw5s2pf	816	2	a	a	DT
cord-256444-grw5s2pf	816	3	result	result	NN
cord-256444-grw5s2pf	816	4	,	,	,
cord-256444-grw5s2pf	816	5	the	the	DT
cord-256444-grw5s2pf	816	6	nascent	nascent	JJ
cord-256444-grw5s2pf	816	7	negative	negative	JJ
cord-256444-grw5s2pf	816	8	-	-	HYPH
cord-256444-grw5s2pf	816	9	strand	strand	NN
cord-256444-grw5s2pf	816	10	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	816	11	RNA	RNA	NNP
cord-256444-grw5s2pf	816	12	fuses	fuse	NNS
cord-256444-grw5s2pf	816	13	with	with	IN
cord-256444-grw5s2pf	816	14	the	the	DT
cord-256444-grw5s2pf	816	15	negative	negative	JJ
cord-256444-grw5s2pf	816	16	-	-	HYPH
cord-256444-grw5s2pf	816	17	strand	strand	NN
cord-256444-grw5s2pf	816	18	leader	leader	NN
cord-256444-grw5s2pf	816	19	sequence	sequence	NN
cord-256444-grw5s2pf	816	20	,	,	,
cord-256444-grw5s2pf	816	21	generating	generate	VBG
cord-256444-grw5s2pf	816	22	a	a	DT
cord-256444-grw5s2pf	816	23	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	816	24	negative	negative	JJ
cord-256444-grw5s2pf	816	25	-	-	HYPH
cord-256444-grw5s2pf	816	26	strand	strand	NN
cord-256444-grw5s2pf	816	27	RNA	RNA	NNP
cord-256444-grw5s2pf	816	28	that	that	WDT
cord-256444-grw5s2pf	816	29	contains	contain	VBZ
cord-256444-grw5s2pf	816	30	an	an	DT
cord-256444-grw5s2pf	816	31	anti	anti	JJ
cord-256444-grw5s2pf	816	32	-	-	JJ
cord-256444-grw5s2pf	816	33	leader	leader	JJ
cord-256444-grw5s2pf	816	34	sequence	sequence	NN
cord-256444-grw5s2pf	816	35	at	at	IN
cord-256444-grw5s2pf	816	36	its	-PRON-	PRP$
cord-256444-grw5s2pf	816	37	3	3	CD
cord-256444-grw5s2pf	816	38	'	'	NN
cord-256444-grw5s2pf	816	39	end	end	NN
cord-256444-grw5s2pf	816	40	and	and	CC
cord-256444-grw5s2pf	816	41	a	a	DT
cord-256444-grw5s2pf	816	42	poly(U	poly(u	NN
cord-256444-grw5s2pf	816	43	)	)	-RRB-
cord-256444-grw5s2pf	816	44	sequence	sequence	NN
cord-256444-grw5s2pf	816	45	at	at	IN
cord-256444-grw5s2pf	816	46	its	-PRON-	PRP$
cord-256444-grw5s2pf	816	47	5	5	CD
cord-256444-grw5s2pf	816	48	'	'	''
cord-256444-grw5s2pf	816	49	end	end	NN
cord-256444-grw5s2pf	816	50	Sethna	Sethna	NNP
cord-256444-grw5s2pf	816	51	et	et	NNP
cord-256444-grw5s2pf	816	52	al	al	NNP
cord-256444-grw5s2pf	816	53	.	.	NNP
cord-256444-grw5s2pf	816	54	,	,	,
cord-256444-grw5s2pf	816	55	1991	1991	CD
cord-256444-grw5s2pf	816	56	)	)	-RRB-
cord-256444-grw5s2pf	816	57	.	.	.
cord-256444-grw5s2pf	817	1	Structurally	structurally	RB
cord-256444-grw5s2pf	817	2	,	,	,
cord-256444-grw5s2pf	817	3	these	these	DT
cord-256444-grw5s2pf	817	4	negativestrand	negativestrand	NN
cord-256444-grw5s2pf	817	5	RNAs	rna	NNS
cord-256444-grw5s2pf	817	6	are	be	VBP
cord-256444-grw5s2pf	817	7	mirror	mirror	NN
cord-256444-grw5s2pf	817	8	images	image	NNS
cord-256444-grw5s2pf	817	9	of	of	IN
cord-256444-grw5s2pf	817	10	the	the	DT
cord-256444-grw5s2pf	817	11	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	817	12	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	818	1	and	and	CC
cord-256444-grw5s2pf	818	2	,	,	,
cord-256444-grw5s2pf	818	3	thus	thus	RB
cord-256444-grw5s2pf	818	4	,	,	,
cord-256444-grw5s2pf	818	5	can	can	MD
cord-256444-grw5s2pf	818	6	potentially	potentially	RB
cord-256444-grw5s2pf	818	7	serve	serve	VB
cord-256444-grw5s2pf	818	8	as	as	IN
cord-256444-grw5s2pf	818	9	a	a	DT
cord-256444-grw5s2pf	818	10	template	template	NN
cord-256444-grw5s2pf	818	11	for	for	IN
cord-256444-grw5s2pf	818	12	uninterrupted	uninterrupted	JJ
cord-256444-grw5s2pf	818	13	transcription	transcription	NN
cord-256444-grw5s2pf	818	14	of	of	IN
cord-256444-grw5s2pf	818	15	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	818	16	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	818	17	.	.	.
cord-256444-grw5s2pf	819	1	In	in	IN
cord-256444-grw5s2pf	819	2	this	this	DT
cord-256444-grw5s2pf	819	3	model	model	NN
cord-256444-grw5s2pf	819	4	,	,	,
cord-256444-grw5s2pf	819	5	the	the	DT
cord-256444-grw5s2pf	819	6	regulation	regulation	NN
cord-256444-grw5s2pf	819	7	of	of	IN
cord-256444-grw5s2pf	819	8	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	819	9	mRNA	mRNA	NNP
cord-256444-grw5s2pf	819	10	transcription	transcription	NN
cord-256444-grw5s2pf	819	11	would	would	MD
cord-256444-grw5s2pf	819	12	be	be	VB
cord-256444-grw5s2pf	819	13	exerted	exert	VBN
cord-256444-grw5s2pf	819	14	on	on	IN
cord-256444-grw5s2pf	819	15	negative	negative	JJ
cord-256444-grw5s2pf	819	16	-	-	HYPH
cord-256444-grw5s2pf	819	17	strand	strand	NN
cord-256444-grw5s2pf	819	18	instead	instead	RB
cord-256444-grw5s2pf	819	19	of	of	IN
cord-256444-grw5s2pf	819	20	positive	positive	JJ
cord-256444-grw5s2pf	819	21	-	-	HYPH
cord-256444-grw5s2pf	819	22	strand	strand	NN
cord-256444-grw5s2pf	819	23	RNA	RNA	NNP
cord-256444-grw5s2pf	819	24	synthesis	synthesis	NN
cord-256444-grw5s2pf	819	25	.	.	.
cord-256444-grw5s2pf	820	1	This	this	DT
cord-256444-grw5s2pf	820	2	model	model	NN
cord-256444-grw5s2pf	820	3	is	be	VBZ
cord-256444-grw5s2pf	820	4	consistent	consistent	JJ
cord-256444-grw5s2pf	820	5	with	with	IN
cord-256444-grw5s2pf	820	6	the	the	DT
cord-256444-grw5s2pf	820	7	following	follow	VBG
cord-256444-grw5s2pf	820	8	observations	observation	NNS
cord-256444-grw5s2pf	820	9	:	:	:
cord-256444-grw5s2pf	820	10	1	1	CD
cord-256444-grw5s2pf	820	11	.	.	.
cord-256444-grw5s2pf	821	1	Subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	821	2	negative	negative	JJ
cord-256444-grw5s2pf	821	3	-	-	HYPH
cord-256444-grw5s2pf	821	4	strand	strand	NN
cord-256444-grw5s2pf	821	5	RNAs	rna	NNS
cord-256444-grw5s2pf	821	6	have	have	VBP
cord-256444-grw5s2pf	821	7	been	be	VBN
cord-256444-grw5s2pf	821	8	detected	detect	VBN
cord-256444-grw5s2pf	821	9	in	in	IN
cord-256444-grw5s2pf	821	10	virusinfected	virusinfected	JJ
cord-256444-grw5s2pf	821	11	cells	cell	NNS
cord-256444-grw5s2pf	821	12	(	(	-LRB-
cord-256444-grw5s2pf	821	13	Sethna	Sethna	NNP
cord-256444-grw5s2pf	821	14	et	et	NNP
cord-256444-grw5s2pf	821	15	al	al	NNP
cord-256444-grw5s2pf	821	16	.	.	NNP
cord-256444-grw5s2pf	821	17	,	,	,
cord-256444-grw5s2pf	821	18	1989	1989	CD
cord-256444-grw5s2pf	821	19	;	;	:
cord-256444-grw5s2pf	821	20	Hofmannet	Hofmannet	NNP
cord-256444-grw5s2pf	821	21	al	al	NNP
cord-256444-grw5s2pf	821	22	.	.	NNP
cord-256444-grw5s2pf	821	23	,	,	,
cord-256444-grw5s2pf	821	24	1990	1990	CD
cord-256444-grw5s2pf	821	25	)	)	-RRB-
cord-256444-grw5s2pf	821	26	.	.	.
cord-256444-grw5s2pf	822	1	These	these	DT
cord-256444-grw5s2pf	822	2	RNAs	rna	NNS
cord-256444-grw5s2pf	822	3	have	have	VBP
cord-256444-grw5s2pf	822	4	structures	structure	NNS
cord-256444-grw5s2pf	822	5	that	that	WDT
cord-256444-grw5s2pf	822	6	are	be	VBP
cord-256444-grw5s2pf	822	7	mirror	mirror	NN
cord-256444-grw5s2pf	822	8	images	image	NNS
cord-256444-grw5s2pf	822	9	of	of	IN
cord-256444-grw5s2pf	822	10	those	those	DT
cord-256444-grw5s2pf	822	11	of	of	IN
cord-256444-grw5s2pf	822	12	the	the	DT
cord-256444-grw5s2pf	822	13	completed	complete	VBN
cord-256444-grw5s2pf	822	14	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	822	15	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	822	16	.	.	.
cord-256444-grw5s2pf	823	1	The	the	DT
cord-256444-grw5s2pf	823	2	relative	relative	JJ
cord-256444-grw5s2pf	823	3	molar	molar	JJ
cord-256444-grw5s2pf	823	4	ratios	ratio	NNS
cord-256444-grw5s2pf	823	5	of	of	IN
cord-256444-grw5s2pf	823	6	the	the	DT
cord-256444-grw5s2pf	823	7	different	different	JJ
cord-256444-grw5s2pf	823	8	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	823	9	negative	negative	JJ
cord-256444-grw5s2pf	823	10	-	-	HYPH
cord-256444-grw5s2pf	823	11	strand	strand	NN
cord-256444-grw5s2pf	823	12	RNAs	rna	NNS
cord-256444-grw5s2pf	823	13	are	be	VBP
cord-256444-grw5s2pf	823	14	similar	similar	JJ
cord-256444-grw5s2pf	823	15	to	to	IN
cord-256444-grw5s2pf	823	16	those	those	DT
cord-256444-grw5s2pf	823	17	of	of	IN
cord-256444-grw5s2pf	823	18	the	the	DT
cord-256444-grw5s2pf	823	19	corresponding	corresponding	JJ
cord-256444-grw5s2pf	823	20	viral	viral	NN
cord-256444-grw5s2pf	823	21	mRNAs	mRNAs	.
cord-256444-grw5s2pf	824	1	(	(	-LRB-
cord-256444-grw5s2pf	824	2	Sethna	Sethna	NNP
cord-256444-grw5s2pf	824	3	et	et	NNP
cord-256444-grw5s2pf	824	4	al	al	NNP
cord-256444-grw5s2pf	824	5	.	.	.
cord-256444-grw5s2pf	825	1	,	,	,
cord-256444-grw5s2pf	825	2	1989	1989	CD
cord-256444-grw5s2pf	825	3	;	;	:
cord-256444-grw5s2pf	825	4	Hofmann	Hofmann	NNP
cord-256444-grw5s2pf	825	5	et	et	NNP
cord-256444-grw5s2pf	825	6	al	al	NNP
cord-256444-grw5s2pf	825	7	.	.	NNP
cord-256444-grw5s2pf	825	8	,	,	,
cord-256444-grw5s2pf	825	9	1990	1990	CD
cord-256444-grw5s2pf	825	10	)	)	-RRB-
cord-256444-grw5s2pf	825	11	.	.	.
cord-256444-grw5s2pf	826	1	in	in	IN
cord-256444-grw5s2pf	826	2	the	the	DT
cord-256444-grw5s2pf	826	3	infection	infection	NN
cord-256444-grw5s2pf	826	4	(	(	-LRB-
cord-256444-grw5s2pf	826	5	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	826	6	and	and	CC
cord-256444-grw5s2pf	826	7	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	826	8	,	,	,
cord-256444-grw5s2pf	826	9	1990	1990	CD
cord-256444-grw5s2pf	826	10	)	)	-RRB-
cord-256444-grw5s2pf	826	11	.	.	.
cord-256444-grw5s2pf	827	1	The	the	DT
cord-256444-grw5s2pf	827	2	smaller	small	JJR
cord-256444-grw5s2pf	827	3	RIs	ri	NNS
cord-256444-grw5s2pf	827	4	were	be	VBD
cord-256444-grw5s2pf	827	5	precursors	precursor	NNS
cord-256444-grw5s2pf	827	6	of	of	IN
cord-256444-grw5s2pf	827	7	the	the	DT
cord-256444-grw5s2pf	827	8	smaller	small	JJR
cord-256444-grw5s2pf	827	9	mRNAs	mrnas	XX
cord-256444-grw5s2pf	827	10	and	and	CC
cord-256444-grw5s2pf	827	11	the	the	DT
cord-256444-grw5s2pf	827	12	larger	large	JJR
cord-256444-grw5s2pf	827	13	RIs	RIs	NNP
cord-256444-grw5s2pf	827	14	generated	generate	VBD
cord-256444-grw5s2pf	827	15	the	the	DT
cord-256444-grw5s2pf	827	16	larger	large	JJR
cord-256444-grw5s2pf	827	17	mRNAs	mrnas	CD
cord-256444-grw5s2pf	827	18	,	,	,
cord-256444-grw5s2pf	827	19	suggesting	suggest	VBG
cord-256444-grw5s2pf	827	20	that	that	IN
cord-256444-grw5s2pf	827	21	each	each	DT
cord-256444-grw5s2pf	827	22	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	827	23	mRNA	mRNA	NNP
cord-256444-grw5s2pf	827	24	was	be	VBD
cord-256444-grw5s2pf	827	25	transcribed	transcribe	VBN
cord-256444-grw5s2pf	827	26	from	from	IN
cord-256444-grw5s2pf	827	27	the	the	DT
cord-256444-grw5s2pf	827	28	corresponding	corresponding	JJ
cord-256444-grw5s2pf	827	29	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	827	30	-	-	HYPH
cord-256444-grw5s2pf	827	31	sized	sized	JJ
cord-256444-grw5s2pf	827	32	negative	negative	JJ
cord-256444-grw5s2pf	827	33	-	-	HYPH
cord-256444-grw5s2pf	827	34	strand	strand	NN
cord-256444-grw5s2pf	827	35	template	template	NN
cord-256444-grw5s2pf	827	36	(	(	-LRB-
cord-256444-grw5s2pf	827	37	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	827	38	and	and	CC
cord-256444-grw5s2pf	827	39	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	827	40	,	,	,
cord-256444-grw5s2pf	827	41	1990	1990	CD
cord-256444-grw5s2pf	827	42	)	)	-RRB-
cord-256444-grw5s2pf	827	43	.	.	.
cord-256444-grw5s2pf	828	1	Another	another	DT
cord-256444-grw5s2pf	828	2	study	study	NN
cord-256444-grw5s2pf	828	3	,	,	,
cord-256444-grw5s2pf	828	4	which	which	WDT
cord-256444-grw5s2pf	828	5	analyzed	analyze	VBD
cord-256444-grw5s2pf	828	6	the	the	DT
cord-256444-grw5s2pf	828	7	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	828	8	RFs	RFs	NNPS
cord-256444-grw5s2pf	828	9	of	of	IN
cord-256444-grw5s2pf	828	10	a	a	DT
cord-256444-grw5s2pf	828	11	temperature	temperature	NN
cord-256444-grw5s2pf	828	12	-	-	HYPH
cord-256444-grw5s2pf	828	13	sensitive	sensitive	JJ
cord-256444-grw5s2pf	828	14	mutant	mutant	NN
cord-256444-grw5s2pf	828	15	of	of	IN
cord-256444-grw5s2pf	828	16	M	M	NNP
cord-256444-grw5s2pf	828	17	W	W	NNP
cord-256444-grw5s2pf	828	18	,	,	,
cord-256444-grw5s2pf	828	19	also	also	RB
cord-256444-grw5s2pf	828	20	suggested	suggest	VBD
cord-256444-grw5s2pf	828	21	that	that	IN
cord-256444-grw5s2pf	828	22	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	828	23	negative	negative	JJ
cord-256444-grw5s2pf	828	24	-	-	HYPH
cord-256444-grw5s2pf	828	25	strand	strand	NN
cord-256444-grw5s2pf	828	26	RNAs	rna	NNS
cord-256444-grw5s2pf	828	27	are	be	VBP
cord-256444-grw5s2pf	828	28	functional	functional	JJ
cord-256444-grw5s2pf	828	29	(	(	-LRB-
cord-256444-grw5s2pf	828	30	Schaad	Schaad	NNP
cord-256444-grw5s2pf	828	31	and	and	CC
cord-256444-grw5s2pf	828	32	Baric	Baric	NNP
cord-256444-grw5s2pf	828	33	,	,	,
cord-256444-grw5s2pf	828	34	1994	1994	CD
cord-256444-grw5s2pf	828	35	)	)	-RRB-
cord-256444-grw5s2pf	828	36	;	;	:
cord-256444-grw5s2pf	828	37	although	although	IN
cord-256444-grw5s2pf	828	38	,	,	,
cord-256444-grw5s2pf	828	39	in	in	IN
cord-256444-grw5s2pf	828	40	this	this	DT
cord-256444-grw5s2pf	828	41	study	study	NN
cord-256444-grw5s2pf	828	42	,	,	,
cord-256444-grw5s2pf	828	43	RIs	RIs	NNP
cord-256444-grw5s2pf	828	44	were	be	VBD
cord-256444-grw5s2pf	828	45	not	not	RB
cord-256444-grw5s2pf	828	46	directly	directly	RB
cord-256444-grw5s2pf	828	47	examined	examine	VBN
cord-256444-grw5s2pf	828	48	.	.	.
cord-256444-grw5s2pf	829	1	3	3	LS
cord-256444-grw5s2pf	829	2	.	.	.
cord-256444-grw5s2pf	830	1	The	the	DT
cord-256444-grw5s2pf	830	2	UV	uv	NN
cord-256444-grw5s2pf	830	3	targets	target	NNS
cord-256444-grw5s2pf	830	4	for	for	IN
cord-256444-grw5s2pf	830	5	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	830	6	mRNA	mRNA	NNP
cord-256444-grw5s2pf	830	7	synthesis	synthesis	NN
cord-256444-grw5s2pf	830	8	at	at	IN
cord-256444-grw5s2pf	830	9	the	the	DT
cord-256444-grw5s2pf	830	10	later	later	JJ
cord-256444-grw5s2pf	830	11	stage	stage	NN
cord-256444-grw5s2pf	830	12	of	of	IN
cord-256444-grw5s2pf	830	13	viral	viral	JJ
cord-256444-grw5s2pf	830	14	replication	replication	NN
cord-256444-grw5s2pf	830	15	are	be	VBP
cord-256444-grw5s2pf	830	16	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	830	17	in	in	IN
cord-256444-grw5s2pf	830	18	length	length	NN
cord-256444-grw5s2pf	831	1	(	(	-LRB-
cord-256444-grw5s2pf	831	2	Jacobs	Jacobs	NNP
cord-256444-grw5s2pf	831	3	et	et	NNP
cord-256444-grw5s2pf	831	4	al	al	NNP
cord-256444-grw5s2pf	831	5	.	.	.
cord-256444-grw5s2pf	832	1	,	,	,
cord-256444-grw5s2pf	832	2	1981	1981	CD
cord-256444-grw5s2pf	832	3	;	;	:
cord-256444-grw5s2pf	832	4	Stern	Stern	NNP
cord-256444-grw5s2pf	832	5	and	and	CC
cord-256444-grw5s2pf	832	6	Sefton	Sefton	NNP
cord-256444-grw5s2pf	832	7	,	,	,
cord-256444-grw5s2pf	832	8	1982a	1982a	CD
cord-256444-grw5s2pf	832	9	;	;	:
cord-256444-grw5s2pf	832	10	Yokomori	Yokomori	NNP
cord-256444-grw5s2pf	832	11	et	et	FW
cord-256444-grw5s2pf	832	12	al	al	NNP
cord-256444-grw5s2pf	832	13	.	.	NNP
cord-256444-grw5s2pf	832	14	,	,	,
cord-256444-grw5s2pf	832	15	1992b	1992b	CD
cord-256444-grw5s2pf	832	16	)	)	-RRB-
cord-256444-grw5s2pf	832	17	,	,	,
cord-256444-grw5s2pf	832	18	roughly	roughly	RB
cord-256444-grw5s2pf	832	19	corresponding	correspond	VBG
cord-256444-grw5s2pf	832	20	to	to	IN
cord-256444-grw5s2pf	832	21	the	the	DT
cord-256444-grw5s2pf	832	22	physical	physical	JJ
cord-256444-grw5s2pf	832	23	lengths	length	NNS
cord-256444-grw5s2pf	832	24	of	of	IN
cord-256444-grw5s2pf	832	25	each	each	DT
cord-256444-grw5s2pf	832	26	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	832	27	mRNA	mRNA	NNP
cord-256444-grw5s2pf	832	28	,	,	,
cord-256444-grw5s2pf	832	29	suggesting	suggest	VBG
cord-256444-grw5s2pf	832	30	that	that	IN
cord-256444-grw5s2pf	832	31	the	the	DT
cord-256444-grw5s2pf	832	32	templates	template	NNS
cord-256444-grw5s2pf	832	33	for	for	IN
cord-256444-grw5s2pf	832	34	these	these	DT
cord-256444-grw5s2pf	832	35	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	832	36	are	be	VBP
cord-256444-grw5s2pf	832	37	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	832	38	.	.	.
cord-256444-grw5s2pf	833	1	4	4	LS
cord-256444-grw5s2pf	833	2	.	.	.
cord-256444-grw5s2pf	834	1	In	in	IN
cord-256444-grw5s2pf	834	2	DI	DI	NNP
cord-256444-grw5s2pf	834	3	RNA	RNA	NNP
cord-256444-grw5s2pf	834	4	systems	system	NNS
cord-256444-grw5s2pf	834	5	(	(	-LRB-
cord-256444-grw5s2pf	834	6	see	see	VB
cord-256444-grw5s2pf	834	7	Section	section	NN
cord-256444-grw5s2pf	834	8	V	v	NN
cord-256444-grw5s2pf	834	9	,	,	,
cord-256444-grw5s2pf	834	10	E,5	E,5	NNP
cord-256444-grw5s2pf	834	11	)	)	-RRB-
cord-256444-grw5s2pf	834	12	,	,	,
cord-256444-grw5s2pf	834	13	when	when	WRB
cord-256444-grw5s2pf	834	14	multiple	multiple	JJ
cord-256444-grw5s2pf	834	15	IG	ig	NN
cord-256444-grw5s2pf	834	16	sequences	sequence	NNS
cord-256444-grw5s2pf	834	17	were	be	VBD
cord-256444-grw5s2pf	834	18	present	present	JJ
cord-256444-grw5s2pf	834	19	,	,	,
cord-256444-grw5s2pf	834	20	the	the	DT
cord-256444-grw5s2pf	834	21	sequences	sequence	NNS
cord-256444-grw5s2pf	834	22	in	in	IN
cord-256444-grw5s2pf	834	23	the	the	DT
cord-256444-grw5s2pf	834	24	3	3	CD
cord-256444-grw5s2pf	834	25	'	'	NN
cord-256444-grw5s2pf	834	26	end	end	NN
cord-256444-grw5s2pf	834	27	often	often	RB
cord-256444-grw5s2pf	834	28	had	have	VBD
cord-256444-grw5s2pf	834	29	a	a	DT
cord-256444-grw5s2pf	834	30	higher	high	JJR
cord-256444-grw5s2pf	834	31	transcription	transcription	NN
cord-256444-grw5s2pf	834	32	efficiency	efficiency	NN
cord-256444-grw5s2pf	834	33	than	than	IN
cord-256444-grw5s2pf	834	34	those	those	DT
cord-256444-grw5s2pf	834	35	at	at	IN
cord-256444-grw5s2pf	834	36	the	the	DT
cord-256444-grw5s2pf	834	37	5	5	CD
cord-256444-grw5s2pf	834	38	'	'	NN
cord-256444-grw5s2pf	834	39	end	end	NN
cord-256444-grw5s2pf	834	40	,	,	,
cord-256444-grw5s2pf	834	41	consistent	consistent	JJ
cord-256444-grw5s2pf	834	42	with	with	IN
cord-256444-grw5s2pf	834	43	the	the	DT
cord-256444-grw5s2pf	834	44	proposal	proposal	NN
cord-256444-grw5s2pf	834	45	that	that	IN
cord-256444-grw5s2pf	834	46	IGs	ig	NNS
cord-256444-grw5s2pf	834	47	serve	serve	VBP
cord-256444-grw5s2pf	834	48	as	as	IN
cord-256444-grw5s2pf	834	49	transcriptional	transcriptional	JJ
cord-256444-grw5s2pf	834	50	termination	termination	NN
cord-256444-grw5s2pf	834	51	sites	site	NNS
cord-256444-grw5s2pf	834	52	,	,	,
cord-256444-grw5s2pf	834	53	which	which	WDT
cord-256444-grw5s2pf	834	54	impede	impede	VBP
cord-256444-grw5s2pf	834	55	the	the	DT
cord-256444-grw5s2pf	834	56	elongation	elongation	NN
cord-256444-grw5s2pf	834	57	of	of	IN
cord-256444-grw5s2pf	834	58	the	the	DT
cord-256444-grw5s2pf	834	59	negative	negative	JJ
cord-256444-grw5s2pf	834	60	-	-	HYPH
cord-256444-grw5s2pf	834	61	strand	strand	NN
cord-256444-grw5s2pf	834	62	RNAs	rna	NNS
cord-256444-grw5s2pf	834	63	(	(	-LRB-
cord-256444-grw5s2pf	834	64	Van	Van	NNP
cord-256444-grw5s2pf	834	65	Marle	Marle	NNP
cord-256444-grw5s2pf	834	66	et	et	NNP
cord-256444-grw5s2pf	834	67	al	al	NNP
cord-256444-grw5s2pf	834	68	.	.	NNP
cord-256444-grw5s2pf	834	69	,	,	,
cord-256444-grw5s2pf	834	70	1995	1995	CD
cord-256444-grw5s2pf	834	71	;	;	:
cord-256444-grw5s2pf	834	72	Krishnan	Krishnan	NNP
cord-256444-grw5s2pf	834	73	et	et	NNP
cord-256444-grw5s2pf	834	74	al	al	NNP
cord-256444-grw5s2pf	834	75	.	.	NNP
cord-256444-grw5s2pf	834	76	,	,	,
cord-256444-grw5s2pf	834	77	1996	1996	CD
cord-256444-grw5s2pf	834	78	)	)	-RRB-
cord-256444-grw5s2pf	834	79	.	.	.
cord-256444-grw5s2pf	835	1	However	however	RB
cord-256444-grw5s2pf	835	2	,	,	,
cord-256444-grw5s2pf	835	3	in	in	IN
cord-256444-grw5s2pf	835	4	some	some	DT
cord-256444-grw5s2pf	835	5	cases	case	NNS
cord-256444-grw5s2pf	835	6	,	,	,
cord-256444-grw5s2pf	835	7	the	the	DT
cord-256444-grw5s2pf	835	8	higher	high	JJR
cord-256444-grw5s2pf	835	9	transcription	transcription	NN
cord-256444-grw5s2pf	835	10	efficiency	efficiency	NN
cord-256444-grw5s2pf	835	11	of	of	IN
cord-256444-grw5s2pf	835	12	the	the	DT
cord-256444-grw5s2pf	835	13	3	3	CD
cord-256444-grw5s2pf	835	14	'	'	POS
cord-256444-grw5s2pf	835	15	proximal	proximal	JJ
cord-256444-grw5s2pf	835	16	IG	IG	NNP
cord-256444-grw5s2pf	835	17	was	be	VBD
cord-256444-grw5s2pf	835	18	observed	observe	VBN
cord-256444-grw5s2pf	835	19	only	only	RB
cord-256444-grw5s2pf	835	20	when	when	WRB
cord-256444-grw5s2pf	835	21	the	the	DT
cord-256444-grw5s2pf	835	22	neighboring	neighbor	VBG
cord-256444-grw5s2pf	835	23	IGs	ig	NNS
cord-256444-grw5s2pf	835	24	were	be	VBD
cord-256444-grw5s2pf	835	25	very	very	RB
cord-256444-grw5s2pf	835	26	close	close	JJ
cord-256444-grw5s2pf	835	27	together	together	RB
cord-256444-grw5s2pf	835	28	,	,	,
cord-256444-grw5s2pf	835	29	suggesting	suggest	VBG
cord-256444-grw5s2pf	835	30	a	a	DT
cord-256444-grw5s2pf	835	31	spatial	spatial	JJ
cord-256444-grw5s2pf	835	32	constraint	constraint	NN
cord-256444-grw5s2pf	835	33	rather	rather	RB
cord-256444-grw5s2pf	835	34	than	than	IN
cord-256444-grw5s2pf	835	35	sequential	sequential	JJ
cord-256444-grw5s2pf	835	36	interference	interference	NN
cord-256444-grw5s2pf	835	37	(	(	-LRB-
cord-256444-grw5s2pf	835	38	Joo	Joo	NNP
cord-256444-grw5s2pf	835	39	and	and	CC
cord-256444-grw5s2pf	835	40	Makino	Makino	NNP
cord-256444-grw5s2pf	835	41	,	,	,
cord-256444-grw5s2pf	835	42	1995	1995	CD
cord-256444-grw5s2pf	835	43	)	)	-RRB-
cord-256444-grw5s2pf	835	44	.	.	.
cord-256444-grw5s2pf	836	1	This	this	DT
cord-256444-grw5s2pf	836	2	model	model	NN
cord-256444-grw5s2pf	836	3	,	,	,
cord-256444-grw5s2pf	836	4	however	however	RB
cord-256444-grw5s2pf	836	5	,	,	,
cord-256444-grw5s2pf	836	6	can	can	MD
cord-256444-grw5s2pf	836	7	not	not	RB
cord-256444-grw5s2pf	836	8	explain	explain	VB
cord-256444-grw5s2pf	836	9	why	why	WRB
cord-256444-grw5s2pf	836	10	the	the	DT
cord-256444-grw5s2pf	836	11	W	w	NN
cord-256444-grw5s2pf	836	12	targets	target	NNS
cord-256444-grw5s2pf	836	13	for	for	IN
cord-256444-grw5s2pf	836	14	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	836	15	mRNA	mRNA	NNP
cord-256444-grw5s2pf	836	16	synthesis	synthesis	NN
cord-256444-grw5s2pf	836	17	early	early	RB
cord-256444-grw5s2pf	836	18	in	in	IN
cord-256444-grw5s2pf	836	19	infection	infection	NN
cord-256444-grw5s2pf	836	20	are	be	VBP
cord-256444-grw5s2pf	836	21	of	of	IN
cord-256444-grw5s2pf	836	22	genomic	genomic	JJ
cord-256444-grw5s2pf	836	23	size	size	NN
cord-256444-grw5s2pf	837	1	(	(	-LRB-
cord-256444-grw5s2pf	837	2	Yokomori	Yokomori	NNP
cord-256444-grw5s2pf	837	3	et	et	FW
cord-256444-grw5s2pf	837	4	al	al	NNP
cord-256444-grw5s2pf	837	5	.	.	.
cord-256444-grw5s2pf	838	1	,	,	,
cord-256444-grw5s2pf	838	2	1992b	1992b	CD
cord-256444-grw5s2pf	838	3	)	)	-RRB-
cord-256444-grw5s2pf	839	1	and	and	CC
cord-256444-grw5s2pf	839	2	why	why	WRB
cord-256444-grw5s2pf	839	3	,	,	,
cord-256444-grw5s2pf	839	4	later	later	RB
cord-256444-grw5s2pf	839	5	in	in	IN
cord-256444-grw5s2pf	839	6	the	the	DT
cord-256444-grw5s2pf	839	7	infection	infection	NN
cord-256444-grw5s2pf	839	8	,	,	,
cord-256444-grw5s2pf	839	9	the	the	DT
cord-256444-grw5s2pf	839	10	targets	target	NNS
cord-256444-grw5s2pf	839	11	for	for	IN
cord-256444-grw5s2pf	839	12	these	these	DT
cord-256444-grw5s2pf	839	13	same	same	JJ
cord-256444-grw5s2pf	839	14	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	839	15	are	be	VBP
cord-256444-grw5s2pf	839	16	still	still	RB
cord-256444-grw5s2pf	839	17	larger	large	JJR
cord-256444-grw5s2pf	839	18	than	than	IN
cord-256444-grw5s2pf	839	19	the	the	DT
cord-256444-grw5s2pf	839	20	respective	respective	JJ
cord-256444-grw5s2pf	839	21	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	840	1	mRNAs	mRNAs	.
cord-256444-grw5s2pf	841	1	but	but	CC
cord-256444-grw5s2pf	841	2	not	not	RB
cord-256444-grw5s2pf	841	3	longer	long	JJR
cord-256444-grw5s2pf	841	4	than	than	IN
cord-256444-grw5s2pf	841	5	genomic	genomic	JJ
cord-256444-grw5s2pf	841	6	size	size	NN
cord-256444-grw5s2pf	841	7	(	(	-LRB-
cord-256444-grw5s2pf	842	1	den	den	NNP
cord-256444-grw5s2pf	842	2	Boon	Boon	NNP
cord-256444-grw5s2pf	842	3	et	et	NNP
cord-256444-grw5s2pf	842	4	al	al	NNP
cord-256444-grw5s2pf	842	5	.	.	NNP
cord-256444-grw5s2pf	842	6	,	,	,
cord-256444-grw5s2pf	842	7	1995	1995	CD
cord-256444-grw5s2pf	842	8	)	)	-RRB-
cord-256444-grw5s2pf	842	9	.	.	.
cord-256444-grw5s2pf	843	1	It	-PRON-	PRP
cord-256444-grw5s2pf	843	2	also	also	RB
cord-256444-grw5s2pf	843	3	can	can	MD
cord-256444-grw5s2pf	843	4	not	not	RB
cord-256444-grw5s2pf	843	5	explain	explain	VB
cord-256444-grw5s2pf	843	6	why	why	WRB
cord-256444-grw5s2pf	843	7	the	the	DT
cord-256444-grw5s2pf	843	8	nature	nature	NN
cord-256444-grw5s2pf	843	9	of	of	IN
cord-256444-grw5s2pf	843	10	the	the	DT
cord-256444-grw5s2pf	843	11	leader	leader	NN
cord-256444-grw5s2pf	843	12	sequence	sequence	NN
cord-256444-grw5s2pf	843	13	can	can	MD
cord-256444-grw5s2pf	843	14	regulate	regulate	VB
cord-256444-grw5s2pf	843	15	differential	differential	JJ
cord-256444-grw5s2pf	843	16	transcription	transcription	NN
cord-256444-grw5s2pf	843	17	of	of	IN
cord-256444-grw5s2pf	843	18	various	various	JJ
cord-256444-grw5s2pf	843	19	mRNA	mRNA	NNP
cord-256444-grw5s2pf	843	20	species	specie	NNS
cord-256444-grw5s2pf	843	21	,	,	,
cord-256444-grw5s2pf	843	22	such	such	JJ
cord-256444-grw5s2pf	843	23	as	as	IN
cord-256444-grw5s2pf	843	24	mRNA	mRNA	NNP
cord-256444-grw5s2pf	843	25	2	2	CD
cord-256444-grw5s2pf	843	26	-	-	SYM
cord-256444-grw5s2pf	843	27	1	1	CD
cord-256444-grw5s2pf	843	28	of	of	IN
cord-256444-grw5s2pf	843	29	MHV	MHV	NNP
cord-256444-grw5s2pf	843	30	,	,	,
cord-256444-grw5s2pf	843	31	inasmuch	inasmuch	IN
cord-256444-grw5s2pf	843	32	as	as	IN
cord-256444-grw5s2pf	843	33	the	the	DT
cord-256444-grw5s2pf	843	34	leader	leader	NN
cord-256444-grw5s2pf	843	35	sequence	sequence	NN
cord-256444-grw5s2pf	843	36	on	on	IN
cord-256444-grw5s2pf	843	37	the	the	DT
cord-256444-grw5s2pf	843	38	template	template	NN
cord-256444-grw5s2pf	843	39	RNA	RNA	NNP
cord-256444-grw5s2pf	843	40	is	be	VBZ
cord-256444-grw5s2pf	843	41	localized	localize	VBN
cord-256444-grw5s2pf	843	42	downstream	downstream	NN
cord-256444-grw5s2pf	843	43	of	of	IN
cord-256444-grw5s2pf	843	44	the	the	DT
cord-256444-grw5s2pf	843	45	transcription	transcription	NN
cord-256444-grw5s2pf	843	46	termination	termination	NN
cord-256444-grw5s2pf	843	47	site	site	NN
cord-256444-grw5s2pf	843	48	for	for	IN
cord-256444-grw5s2pf	843	49	negative	negative	JJ
cord-256444-grw5s2pf	843	50	-	-	HYPH
cord-256444-grw5s2pf	843	51	strand	strand	NN
cord-256444-grw5s2pf	843	52	RNA	RNA	NNP
cord-256444-grw5s2pf	843	53	synthesis	synthesis	NN
cord-256444-grw5s2pf	843	54	.	.	.
cord-256444-grw5s2pf	844	1	Finally	finally	RB
cord-256444-grw5s2pf	844	2	,	,	,
cord-256444-grw5s2pf	844	3	it	-PRON-	PRP
cord-256444-grw5s2pf	844	4	is	be	VBZ
cord-256444-grw5s2pf	844	5	difficult	difficult	JJ
cord-256444-grw5s2pf	844	6	to	to	TO
cord-256444-grw5s2pf	844	7	explain	explain	VB
cord-256444-grw5s2pf	844	8	why	why	WRB
cord-256444-grw5s2pf	844	9	the	the	DT
cord-256444-grw5s2pf	844	10	leader	leader	NN
cord-256444-grw5s2pf	844	11	RNAs	rna	NNS
cord-256444-grw5s2pf	844	12	are	be	VBP
cord-256444-grw5s2pf	844	13	derived	derive	VBN
cord-256444-grw5s2pf	844	14	in	in	IN
cord-256444-grw5s2pf	844	15	trans	trans	NNP
cord-256444-grw5s2pf	844	16	.	.	.
cord-256444-grw5s2pf	844	17	c.	c.	NNP
cord-256444-grw5s2pf	844	18	Trans	Trans	NNP
cord-256444-grw5s2pf	844	19	-	-	NNP
cord-256444-grw5s2pf	844	20	Splicing	Splicing	NNP
cord-256444-grw5s2pf	844	21	of	of	IN
cord-256444-grw5s2pf	844	22	Nascent	Nascent	NNP
cord-256444-grw5s2pf	844	23	RNA	RNA	NNP
cord-256444-grw5s2pf	844	24	Transcripts	Transcripts	NNPS
cord-256444-grw5s2pf	844	25	.	.	.
cord-256444-grw5s2pf	845	1	This	this	DT
cord-256444-grw5s2pf	845	2	model	model	NN
cord-256444-grw5s2pf	845	3	proposes	propose	VBZ
cord-256444-grw5s2pf	845	4	that	that	IN
cord-256444-grw5s2pf	845	5	the	the	DT
cord-256444-grw5s2pf	845	6	fdl	fdl	NNP
cord-256444-grw5s2pf	845	7	-	-	HYPH
cord-256444-grw5s2pf	845	8	length	length	NN
cord-256444-grw5s2pf	845	9	positive	positive	JJ
cord-256444-grw5s2pf	845	10	-	-	:
cord-256444-grw5s2pf	845	11	or	or	CC
cord-256444-grw5s2pf	845	12	negative	negative	JJ
cord-256444-grw5s2pf	845	13	-	-	HYPH
cord-256444-grw5s2pf	845	14	strand	strand	NN
cord-256444-grw5s2pf	845	15	RNAs	rna	NNS
cord-256444-grw5s2pf	845	16	are	be	VBP
cord-256444-grw5s2pf	845	17	spliced	splice	VBN
cord-256444-grw5s2pf	845	18	posttranscriptionally	posttranscriptionally	RB
cord-256444-grw5s2pf	845	19	to	to	TO
cord-256444-grw5s2pf	845	20	generate	generate	VB
cord-256444-grw5s2pf	845	21	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	845	22	RNAs	rna	NNS
cord-256444-grw5s2pf	845	23	.	.	.
cord-256444-grw5s2pf	846	1	It	-PRON-	PRP
cord-256444-grw5s2pf	846	2	was	be	VBD
cord-256444-grw5s2pf	846	3	initially	initially	RB
cord-256444-grw5s2pf	846	4	considered	consider	VBN
cord-256444-grw5s2pf	846	5	unlikely	unlikely	JJ
cord-256444-grw5s2pf	846	6	because	because	IN
cord-256444-grw5s2pf	846	7	of	of	IN
cord-256444-grw5s2pf	846	8	the	the	DT
cord-256444-grw5s2pf	846	9	findings	finding	NNS
cord-256444-grw5s2pf	846	10	that	that	WDT
cord-256444-grw5s2pf	846	11	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	846	12	replicates	replicate	VBZ
cord-256444-grw5s2pf	846	13	in	in	IN
cord-256444-grw5s2pf	846	14	the	the	DT
cord-256444-grw5s2pf	846	15	cytoplasm	cytoplasm	NN
cord-256444-grw5s2pf	846	16	rather	rather	RB
cord-256444-grw5s2pf	846	17	than	than	IN
cord-256444-grw5s2pf	846	18	in	in	IN
cord-256444-grw5s2pf	846	19	the	the	DT
cord-256444-grw5s2pf	846	20	nucleus	nucleus	NN
cord-256444-grw5s2pf	847	1	Wilhelmsen	Wilhelmsen	NNP
cord-256444-grw5s2pf	847	2	et	et	NNP
cord-256444-grw5s2pf	847	3	al	al	NNP
cord-256444-grw5s2pf	847	4	.	.	NNP
cord-256444-grw5s2pf	847	5	,	,	,
cord-256444-grw5s2pf	847	6	1981	1981	CD
cord-256444-grw5s2pf	847	7	)	)	-RRB-
cord-256444-grw5s2pf	848	1	,	,	,
cord-256444-grw5s2pf	848	2	where	where	WRB
cord-256444-grw5s2pf	848	3	the	the	DT
cord-256444-grw5s2pf	848	4	splicing	splicing	NN
cord-256444-grw5s2pf	848	5	machinery	machinery	NN
cord-256444-grw5s2pf	848	6	is	be	VBZ
cord-256444-grw5s2pf	848	7	present	present	JJ
cord-256444-grw5s2pf	848	8	,	,	,
cord-256444-grw5s2pf	848	9	and	and	CC
cord-256444-grw5s2pf	848	10	that	that	DT
cord-256444-grw5s2pf	848	11	UV	uv	NN
cord-256444-grw5s2pf	848	12	target	target	NN
cord-256444-grw5s2pf	848	13	sizes	size	NNS
cord-256444-grw5s2pf	848	14	of	of	IN
cord-256444-grw5s2pf	848	15	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	848	16	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	848	17	are	be	VBP
cord-256444-grw5s2pf	848	18	equivalent	equivalent	JJ
cord-256444-grw5s2pf	848	19	to	to	IN
cord-256444-grw5s2pf	848	20	the	the	DT
cord-256444-grw5s2pf	848	21	physical	physical	JJ
cord-256444-grw5s2pf	848	22	sizes	size	NNS
cord-256444-grw5s2pf	848	23	of	of	IN
cord-256444-grw5s2pf	848	24	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	848	25	mRNAs	mRNAs	.
cord-256444-grw5s2pf	849	1	(	(	-LRB-
cord-256444-grw5s2pf	849	2	Jacobs	Jacobs	NNP
cord-256444-grw5s2pf	849	3	et	et	NNP
cord-256444-grw5s2pf	849	4	al	al	NNP
cord-256444-grw5s2pf	849	5	.	.	NNP
cord-256444-grw5s2pf	849	6	,	,	,
cord-256444-grw5s2pf	849	7	1981	1981	CD
cord-256444-grw5s2pf	849	8	)	)	-RRB-
cord-256444-grw5s2pf	849	9	.	.	.
cord-256444-grw5s2pf	850	1	Furthermore	furthermore	RB
cord-256444-grw5s2pf	850	2	,	,	,
cord-256444-grw5s2pf	850	3	there	there	EX
cord-256444-grw5s2pf	850	4	are	be	VBP
cord-256444-grw5s2pf	850	5	no	no	DT
cord-256444-grw5s2pf	850	6	consensus	consensus	NN
cord-256444-grw5s2pf	850	7	splicing	splice	VBG
cord-256444-grw5s2pf	850	8	donor	donor	NN
cord-256444-grw5s2pf	850	9	and	and	CC
cord-256444-grw5s2pf	850	10	acceptor	acceptor	NN
cord-256444-grw5s2pf	850	11	sequences	sequence	NNS
cord-256444-grw5s2pf	850	12	in	in	IN
cord-256444-grw5s2pf	850	13	the	the	DT
cord-256444-grw5s2pf	850	14	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	850	15	genomic	genomic	JJ
cord-256444-grw5s2pf	850	16	RNAs	rna	NNS
cord-256444-grw5s2pf	850	17	.	.	.
cord-256444-grw5s2pf	851	1	However	however	RB
cord-256444-grw5s2pf	851	2	,	,	,
cord-256444-grw5s2pf	851	3	the	the	DT
cord-256444-grw5s2pf	851	4	trans	trans	JJ
cord-256444-grw5s2pf	851	5	-	-	JJ
cord-256444-grw5s2pf	851	6	splicing	splicing	NN
cord-256444-grw5s2pf	851	7	model	model	NN
cord-256444-grw5s2pf	851	8	is	be	VBZ
cord-256444-grw5s2pf	851	9	compatible	compatible	JJ
cord-256444-grw5s2pf	851	10	with	with	IN
cord-256444-grw5s2pf	851	11	recent	recent	JJ
cord-256444-grw5s2pf	851	12	findings	finding	NNS
cord-256444-grw5s2pf	851	13	that	that	WDT
cord-256444-grw5s2pf	851	14	early	early	RB
cord-256444-grw5s2pf	851	15	in	in	IN
cord-256444-grw5s2pf	851	16	infection	infection	NN
cord-256444-grw5s2pf	851	17	,	,	,
cord-256444-grw5s2pf	851	18	the	the	DT
cord-256444-grw5s2pf	851	19	W	w	NN
cord-256444-grw5s2pf	851	20	targets	target	NNS
cord-256444-grw5s2pf	851	21	for	for	IN
cord-256444-grw5s2pf	851	22	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	851	23	mRNA	mRNA	NNP
cord-256444-grw5s2pf	851	24	synthesis	synthesis	NN
cord-256444-grw5s2pf	851	25	are	be	VBP
cord-256444-grw5s2pf	851	26	of	of	IN
cord-256444-grw5s2pf	851	27	genomic	genomic	JJ
cord-256444-grw5s2pf	851	28	length	length	NN
cord-256444-grw5s2pf	852	1	(	(	-LRB-
cord-256444-grw5s2pf	852	2	Yokomori	Yokomori	NNP
cord-256444-grw5s2pf	852	3	et	et	FW
cord-256444-grw5s2pf	852	4	al	al	NNP
cord-256444-grw5s2pf	852	5	.	.	NNP
cord-256444-grw5s2pf	852	6	,	,	,
cord-256444-grw5s2pf	852	7	1992b	1992b	CD
cord-256444-grw5s2pf	852	8	)	)	-RRB-
cord-256444-grw5s2pf	852	9	,	,	,
cord-256444-grw5s2pf	852	10	and	and	CC
cord-256444-grw5s2pf	852	11	that	that	IN
cord-256444-grw5s2pf	852	12	both	both	CC
cord-256444-grw5s2pf	852	13	the	the	DT
cord-256444-grw5s2pf	852	14	leader	leader	NN
cord-256444-grw5s2pf	852	15	RNA	RNA	NNP
cord-256444-grw5s2pf	852	16	and	and	CC
cord-256444-grw5s2pf	852	17	IG	IG	NNP
cord-256444-grw5s2pf	852	18	sequence	sequence	NN
cord-256444-grw5s2pf	852	19	of	of	IN
cord-256444-grw5s2pf	852	20	MHV	MHV	NNP
cord-256444-grw5s2pf	852	21	negative	negative	JJ
cord-256444-grw5s2pf	852	22	-	-	HYPH
cord-256444-grw5s2pf	852	23	strand	strand	NN
cord-256444-grw5s2pf	852	24	RNA	RNA	NNP
cord-256444-grw5s2pf	852	25	bind	bind	NN
cord-256444-grw5s2pf	852	26	to	to	IN
cord-256444-grw5s2pf	852	27	a	a	DT
cord-256444-grw5s2pf	852	28	cellular	cellular	JJ
cord-256444-grw5s2pf	852	29	factor	factor	NN
cord-256444-grw5s2pf	852	30	,	,	,
cord-256444-grw5s2pf	852	31	heterogeneous	heterogeneous	JJ
cord-256444-grw5s2pf	852	32	nuclear	nuclear	JJ
cord-256444-grw5s2pf	852	33	RNP	RNP	NNP
cord-256444-grw5s2pf	852	34	(	(	-LRB-
cord-256444-grw5s2pf	852	35	hnRNP	hnrnp	NN
cord-256444-grw5s2pf	852	36	)	)	-RRB-
cord-256444-grw5s2pf	853	1	Al	Al	NNP
cord-256444-grw5s2pf	853	2	,	,	,
cord-256444-grw5s2pf	853	3	which	which	WDT
cord-256444-grw5s2pf	853	4	is	be	VBZ
cord-256444-grw5s2pf	853	5	involved	involve	VBN
cord-256444-grw5s2pf	853	6	in	in	IN
cord-256444-grw5s2pf	853	7	alternative	alternative	JJ
cord-256444-grw5s2pf	853	8	RNA	RNA	NNP
cord-256444-grw5s2pf	853	9	splicing	splicing	NN
cord-256444-grw5s2pf	853	10	 	 	_SP
cord-256444-grw5s2pf	853	11	H.-P.	h.-p.	XX
cord-256444-grw5s2pf	854	1	Li	Li	NNP
cord-256444-grw5s2pf	854	2	and	and	CC
cord-256444-grw5s2pf	854	3	M.	M.	NNP
cord-256444-grw5s2pf	854	4	M.	M.	NNP
cord-256444-grw5s2pf	854	5	C.	C.	NNP
cord-256444-grw5s2pf	854	6	Lai	Lai	NNP
cord-256444-grw5s2pf	854	7	,	,	,
cord-256444-grw5s2pf	854	8	unpublished	unpublished	JJ
cord-256444-grw5s2pf	854	9	observation	observation	NN
cord-256444-grw5s2pf	854	10	)	)	-RRB-
cord-256444-grw5s2pf	854	11	.	.	.
cord-256444-grw5s2pf	855	1	A	a	DT
cord-256444-grw5s2pf	855	2	modified	modify	VBN
cord-256444-grw5s2pf	855	3	splicing	splicing	NN
cord-256444-grw5s2pf	855	4	model	model	NN
cord-256444-grw5s2pf	855	5	thus	thus	RB
cord-256444-grw5s2pf	855	6	can	can	MD
cord-256444-grw5s2pf	855	7	be	be	VB
cord-256444-grw5s2pf	855	8	proposed	propose	VBN
cord-256444-grw5s2pf	855	9	as	as	IN
cord-256444-grw5s2pf	855	10	follows	follow	VBZ
cord-256444-grw5s2pf	855	11	:	:	:
cord-256444-grw5s2pf	855	12	a	a	DT
cord-256444-grw5s2pf	855	13	full	full	JJ
cord-256444-grw5s2pf	855	14	-	-	HYPH
cord-256444-grw5s2pf	855	15	length	length	NN
cord-256444-grw5s2pf	855	16	negative	negative	JJ
cord-256444-grw5s2pf	855	17	-	-	HYPH
cord-256444-grw5s2pf	855	18	strand	strand	NN
cord-256444-grw5s2pf	855	19	RNA	RNA	NNP
cord-256444-grw5s2pf	855	20	is	be	VBZ
cord-256444-grw5s2pf	855	21	first	first	RB
cord-256444-grw5s2pf	855	22	synthesized	synthesize	VBN
cord-256444-grw5s2pf	855	23	.	.	.
cord-256444-grw5s2pf	856	1	Components	component	NNS
cord-256444-grw5s2pf	856	2	of	of	IN
cord-256444-grw5s2pf	856	3	the	the	DT
cord-256444-grw5s2pf	856	4	splicing	splicing	NN
cord-256444-grw5s2pf	856	5	machinery	machinery	NN
cord-256444-grw5s2pf	856	6	derived	derive	VBN
cord-256444-grw5s2pf	856	7	from	from	IN
cord-256444-grw5s2pf	856	8	the	the	DT
cord-256444-grw5s2pf	856	9	nucleus	nucleus	NN
cord-256444-grw5s2pf	856	10	or	or	CC
cord-256444-grw5s2pf	856	11	cytoplasm	cytoplasm	JJ
cord-256444-grw5s2pf	856	12	then	then	RB
cord-256444-grw5s2pf	856	13	bind	bind	VB
cord-256444-grw5s2pf	856	14	to	to	IN
cord-256444-grw5s2pf	856	15	the	the	DT
cord-256444-grw5s2pf	856	16	leader	leader	NN
cord-256444-grw5s2pf	856	17	sequence	sequence	NN
cord-256444-grw5s2pf	856	18	and	and	CC
cord-256444-grw5s2pf	856	19	IG	ig	NN
cord-256444-grw5s2pf	856	20	sites	site	NNS
cord-256444-grw5s2pf	856	21	on	on	IN
cord-256444-grw5s2pf	856	22	the	the	DT
cord-256444-grw5s2pf	856	23	negative	negative	JJ
cord-256444-grw5s2pf	856	24	-	-	HYPH
cord-256444-grw5s2pf	856	25	strand	strand	NN
cord-256444-grw5s2pf	856	26	RNA	RNA	NNP
cord-256444-grw5s2pf	856	27	and	and	CC
cord-256444-grw5s2pf	856	28	form	form	VB
cord-256444-grw5s2pf	856	29	a	a	DT
cord-256444-grw5s2pf	856	30	splicing	splicing	NN
cord-256444-grw5s2pf	856	31	complex	complex	NN
cord-256444-grw5s2pf	856	32	.	.	.
cord-256444-grw5s2pf	857	1	The	the	DT
cord-256444-grw5s2pf	857	2	leader	leader	NN
cord-256444-grw5s2pf	857	3	and	and	CC
cord-256444-grw5s2pf	857	4	IG	IG	NNP
cord-256444-grw5s2pf	857	5	can	can	MD
cord-256444-grw5s2pf	857	6	be	be	VB
cord-256444-grw5s2pf	857	7	derived	derive	VBN
cord-256444-grw5s2pf	857	8	from	from	IN
cord-256444-grw5s2pf	857	9	different	different	JJ
cord-256444-grw5s2pf	857	10	RNA	RNA	NNP
cord-256444-grw5s2pf	857	11	molecules	molecule	NNS
cord-256444-grw5s2pf	857	12	.	.	.
cord-256444-grw5s2pf	858	1	Splicing	splice	VBG
cord-256444-grw5s2pf	858	2	between	between	IN
cord-256444-grw5s2pf	858	3	the	the	DT
cord-256444-grw5s2pf	858	4	leader	leader	NN
cord-256444-grw5s2pf	858	5	and	and	CC
cord-256444-grw5s2pf	858	6	IG	IG	NNP
cord-256444-grw5s2pf	858	7	generates	generate	VBZ
cord-256444-grw5s2pf	858	8	a	a	DT
cord-256444-grw5s2pf	858	9	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	858	10	negative	negative	JJ
cord-256444-grw5s2pf	858	11	-	-	HYPH
cord-256444-grw5s2pf	858	12	strand	strand	NN
cord-256444-grw5s2pf	858	13	RNA	RNA	NNP
cord-256444-grw5s2pf	858	14	.	.	.
cord-256444-grw5s2pf	859	1	Once	once	IN
cord-256444-grw5s2pf	859	2	the	the	DT
cord-256444-grw5s2pf	859	3	spliced	splice	VBN
cord-256444-grw5s2pf	859	4	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	859	5	negative	negative	JJ
cord-256444-grw5s2pf	859	6	-	-	HYPH
cord-256444-grw5s2pf	859	7	strand	strand	NN
cord-256444-grw5s2pf	859	8	RNAs	rna	NNS
cord-256444-grw5s2pf	859	9	are	be	VBP
cord-256444-grw5s2pf	859	10	generated	generate	VBN
cord-256444-grw5s2pf	859	11	,	,	,
cord-256444-grw5s2pf	859	12	they	-PRON-	PRP
cord-256444-grw5s2pf	859	13	are	be	VBP
cord-256444-grw5s2pf	859	14	used	use	VBN
cord-256444-grw5s2pf	859	15	as	as	IN
cord-256444-grw5s2pf	859	16	templates	template	NNS
cord-256444-grw5s2pf	859	17	for	for	IN
cord-256444-grw5s2pf	859	18	subsequent	subsequent	JJ
cord-256444-grw5s2pf	859	19	mRNA	mRNA	NNP
cord-256444-grw5s2pf	859	20	synthesis	synthesis	NN
cord-256444-grw5s2pf	859	21	.	.	.
cord-256444-grw5s2pf	860	1	Later	later	RB
cord-256444-grw5s2pf	860	2	in	in	IN
cord-256444-grw5s2pf	860	3	infection	infection	NN
cord-256444-grw5s2pf	860	4	,	,	,
cord-256444-grw5s2pf	860	5	even	even	RB
cord-256444-grw5s2pf	860	6	the	the	DT
cord-256444-grw5s2pf	860	7	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	860	8	negative	negative	JJ
cord-256444-grw5s2pf	860	9	-	-	HYPH
cord-256444-grw5s2pf	860	10	strand	strand	NN
cord-256444-grw5s2pf	860	11	RNAs	rna	NNS
cord-256444-grw5s2pf	860	12	may	may	MD
cord-256444-grw5s2pf	860	13	be	be	VB
cord-256444-grw5s2pf	860	14	able	able	JJ
cord-256444-grw5s2pf	860	15	to	to	TO
cord-256444-grw5s2pf	860	16	participate	participate	VB
cord-256444-grw5s2pf	860	17	in	in	IN
cord-256444-grw5s2pf	860	18	RNA	RNA	NNP
cord-256444-grw5s2pf	860	19	splicing	splicing	NN
cord-256444-grw5s2pf	860	20	to	to	TO
cord-256444-grw5s2pf	860	21	generate	generate	VB
cord-256444-grw5s2pf	860	22	smaller	small	JJR
cord-256444-grw5s2pf	860	23	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	860	24	negativestrand	negativestrand	NN
cord-256444-grw5s2pf	860	25	RNAs	rna	NNS
cord-256444-grw5s2pf	860	26	because	because	IN
cord-256444-grw5s2pf	860	27	they	-PRON-	PRP
cord-256444-grw5s2pf	860	28	themselves	-PRON-	PRP
cord-256444-grw5s2pf	860	29	also	also	RB
cord-256444-grw5s2pf	860	30	contain	contain	VBP
cord-256444-grw5s2pf	860	31	the	the	DT
cord-256444-grw5s2pf	860	32	leader	leader	NN
cord-256444-grw5s2pf	860	33	and	and	CC
cord-256444-grw5s2pf	860	34	IG	IG	NNP
cord-256444-grw5s2pf	860	35	sequences	sequence	NNS
cord-256444-grw5s2pf	860	36	.	.	.
cord-256444-grw5s2pf	861	1	This	this	DT
cord-256444-grw5s2pf	861	2	model	model	NN
cord-256444-grw5s2pf	861	3	may	may	MD
cord-256444-grw5s2pf	861	4	thus	thus	RB
cord-256444-grw5s2pf	861	5	explain	explain	VB
cord-256444-grw5s2pf	861	6	why	why	WRB
cord-256444-grw5s2pf	861	7	the	the	DT
cord-256444-grw5s2pf	861	8	W	w	NN
cord-256444-grw5s2pf	861	9	target	target	NN
cord-256444-grw5s2pf	861	10	for	for	IN
cord-256444-grw5s2pf	861	11	mRNA	mrna	NN
cord-256444-grw5s2pf	861	12	transcription	transcription	NN
cord-256444-grw5s2pf	861	13	is	be	VBZ
cord-256444-grw5s2pf	861	14	of	of	IN
cord-256444-grw5s2pf	861	15	genomic	genomic	JJ
cord-256444-grw5s2pf	861	16	length	length	NN
cord-256444-grw5s2pf	861	17	early	early	RB
cord-256444-grw5s2pf	861	18	in	in	IN
cord-256444-grw5s2pf	861	19	infection	infection	NN
cord-256444-grw5s2pf	862	1	(	(	-LRB-
cord-256444-grw5s2pf	862	2	Yokomori	Yokomori	NNP
cord-256444-grw5s2pf	862	3	et	et	FW
cord-256444-grw5s2pf	862	4	al	al	NNP
cord-256444-grw5s2pf	862	5	.	.	NNP
cord-256444-grw5s2pf	862	6	,	,	,
cord-256444-grw5s2pf	862	7	1992b	1992b	CD
cord-256444-grw5s2pf	862	8	)	)	-RRB-
cord-256444-grw5s2pf	862	9	and	and	CC
cord-256444-grw5s2pf	862	10	may	may	MD
cord-256444-grw5s2pf	862	11	shed	shed	VB
cord-256444-grw5s2pf	862	12	light	light	NN
cord-256444-grw5s2pf	862	13	on	on	IN
cord-256444-grw5s2pf	862	14	the	the	DT
cord-256444-grw5s2pf	862	15	recent	recent	JJ
cord-256444-grw5s2pf	862	16	puzzling	puzzling	JJ
cord-256444-grw5s2pf	862	17	finding	finding	NN
cord-256444-grw5s2pf	862	18	that	that	IN
cord-256444-grw5s2pf	862	19	later	later	RB
cord-256444-grw5s2pf	862	20	in	in	IN
cord-256444-grw5s2pf	862	21	infection	infection	NN
cord-256444-grw5s2pf	862	22	,	,	,
cord-256444-grw5s2pf	862	23	the	the	DT
cord-256444-grw5s2pf	862	24	W	w	NN
cord-256444-grw5s2pf	862	25	target	target	NN
cord-256444-grw5s2pf	862	26	sizes	size	NNS
cord-256444-grw5s2pf	862	27	are	be	VBP
cord-256444-grw5s2pf	862	28	still	still	RB
cord-256444-grw5s2pf	862	29	larger	large	JJR
cord-256444-grw5s2pf	862	30	than	than	IN
cord-256444-grw5s2pf	862	31	the	the	DT
cord-256444-grw5s2pf	862	32	actual	actual	JJ
cord-256444-grw5s2pf	862	33	sizes	size	NNS
cord-256444-grw5s2pf	862	34	of	of	IN
cord-256444-grw5s2pf	862	35	the	the	DT
cord-256444-grw5s2pf	862	36	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	862	37	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	863	1	(	(	-LRB-
cord-256444-grw5s2pf	863	2	den	den	NNP
cord-256444-grw5s2pf	863	3	Boon	Boon	NNP
cord-256444-grw5s2pf	863	4	et	et	NNP
cord-256444-grw5s2pf	863	5	al	al	NNP
cord-256444-grw5s2pf	863	6	.	.	NNP
cord-256444-grw5s2pf	863	7	,	,	,
cord-256444-grw5s2pf	863	8	1995	1995	CD
cord-256444-grw5s2pf	863	9	)	)	-RRB-
cord-256444-grw5s2pf	863	10	.	.	.
cord-256444-grw5s2pf	864	1	It	-PRON-	PRP
cord-256444-grw5s2pf	864	2	also	also	RB
cord-256444-grw5s2pf	864	3	explains	explain	VBZ
cord-256444-grw5s2pf	864	4	the	the	DT
cord-256444-grw5s2pf	864	5	functional	functional	JJ
cord-256444-grw5s2pf	864	6	roles	role	NNS
cord-256444-grw5s2pf	864	7	of	of	IN
cord-256444-grw5s2pf	864	8	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	864	9	RIs	RIs	NNP
cord-256444-grw5s2pf	864	10	(	(	-LRB-
cord-256444-grw5s2pf	864	11	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	864	12	and	and	CC
cord-256444-grw5s2pf	864	13	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	864	14	,	,	,
cord-256444-grw5s2pf	864	15	1990	1990	CD
cord-256444-grw5s2pf	864	16	)	)	-RRB-
cord-256444-grw5s2pf	864	17	.	.	.
cord-256444-grw5s2pf	865	1	This	this	DT
cord-256444-grw5s2pf	865	2	potential	potential	JJ
cord-256444-grw5s2pf	865	3	splicing	splicing	NN
cord-256444-grw5s2pf	865	4	,	,	,
cord-256444-grw5s2pf	865	5	however	however	RB
cord-256444-grw5s2pf	865	6	,	,	,
cord-256444-grw5s2pf	865	7	must	must	MD
cord-256444-grw5s2pf	865	8	be	be	VB
cord-256444-grw5s2pf	865	9	different	different	JJ
cord-256444-grw5s2pf	865	10	from	from	IN
cord-256444-grw5s2pf	865	11	conventional	conventional	JJ
cord-256444-grw5s2pf	865	12	RNA	RNA	NNP
cord-256444-grw5s2pf	865	13	splicing	splicing	NN
cord-256444-grw5s2pf	865	14	because	because	IN
cord-256444-grw5s2pf	865	15	it	-PRON-	PRP
cord-256444-grw5s2pf	865	16	occurs	occur	VBZ
cord-256444-grw5s2pf	865	17	in	in	IN
cord-256444-grw5s2pf	865	18	the	the	DT
cord-256444-grw5s2pf	865	19	cytoplasm	cytoplasm	NN
cord-256444-grw5s2pf	865	20	,	,	,
cord-256444-grw5s2pf	865	21	and	and	CC
cord-256444-grw5s2pf	865	22	the	the	DT
cord-256444-grw5s2pf	865	23	splicing	splicing	NN
cord-256444-grw5s2pf	865	24	donor	donor	NN
cord-256444-grw5s2pf	865	25	and	and	CC
cord-256444-grw5s2pf	865	26	acceptor	acceptor	NN
cord-256444-grw5s2pf	865	27	sequences	sequence	NNS
cord-256444-grw5s2pf	865	28	must	must	MD
cord-256444-grw5s2pf	865	29	also	also	RB
cord-256444-grw5s2pf	865	30	be	be	VB
cord-256444-grw5s2pf	865	31	different	different	JJ
cord-256444-grw5s2pf	865	32	from	from	IN
cord-256444-grw5s2pf	865	33	the	the	DT
cord-256444-grw5s2pf	865	34	conventional	conventional	JJ
cord-256444-grw5s2pf	865	35	ones	one	NNS
cord-256444-grw5s2pf	865	36	.	.	.
cord-256444-grw5s2pf	866	1	Since	since	IN
cord-256444-grw5s2pf	866	2	some	some	DT
cord-256444-grw5s2pf	866	3	of	of	IN
cord-256444-grw5s2pf	866	4	the	the	DT
cord-256444-grw5s2pf	866	5	splicing	splicing	NN
cord-256444-grw5s2pf	866	6	factors	factor	NNS
cord-256444-grw5s2pf	866	7	are	be	VBP
cord-256444-grw5s2pf	866	8	probably	probably	RB
cord-256444-grw5s2pf	866	9	derived	derive	VBN
cord-256444-grw5s2pf	866	10	from	from	IN
cord-256444-grw5s2pf	866	11	the	the	DT
cord-256444-grw5s2pf	866	12	nucleus	nucleus	NN
cord-256444-grw5s2pf	866	13	,	,	,
cord-256444-grw5s2pf	866	14	this	this	DT
cord-256444-grw5s2pf	866	15	model	model	NN
cord-256444-grw5s2pf	866	16	predicts	predict	VBZ
cord-256444-grw5s2pf	866	17	that	that	IN
cord-256444-grw5s2pf	866	18	nuclear	nuclear	JJ
cord-256444-grw5s2pf	866	19	functions	function	NNS
cord-256444-grw5s2pf	866	20	are	be	VBP
cord-256444-grw5s2pf	866	21	involved	involve	VBN
cord-256444-grw5s2pf	866	22	in	in	IN
cord-256444-grw5s2pf	866	23	MHV	MHV	NNP
cord-256444-grw5s2pf	866	24	RNA	RNA	NNP
cord-256444-grw5s2pf	866	25	transcription	transcription	NN
cord-256444-grw5s2pf	866	26	.	.	.
cord-256444-grw5s2pf	867	1	Based	base	VBN
cord-256444-grw5s2pf	867	2	on	on	IN
cord-256444-grw5s2pf	867	3	the	the	DT
cord-256444-grw5s2pf	867	4	findings	finding	NNS
cord-256444-grw5s2pf	867	5	that	that	WDT
cord-256444-grw5s2pf	867	6	some	some	DT
cord-256444-grw5s2pf	867	7	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	867	8	,	,	,
cord-256444-grw5s2pf	867	9	including	include	VBG
cord-256444-grw5s2pf	867	10	BCV	BCV	NNP
cord-256444-grw5s2pf	867	11	,	,	,
cord-256444-grw5s2pf	867	12	TGEV	TGEV	NNP
cord-256444-grw5s2pf	867	13	,	,	,
cord-256444-grw5s2pf	867	14	and	and	CC
cord-256444-grw5s2pf	867	15	IBV	IBV	NNP
cord-256444-grw5s2pf	867	16	(	(	-LRB-
cord-256444-grw5s2pf	867	17	Sethna	Sethna	NNP
cord-256444-grw5s2pf	867	18	et	et	NNP
cord-256444-grw5s2pf	867	19	al	al	NNP
cord-256444-grw5s2pf	867	20	.	.	NNP
cord-256444-grw5s2pf	867	21	,	,	,
cord-256444-grw5s2pf	867	22	1989	1989	CD
cord-256444-grw5s2pf	867	23	;	;	:
cord-256444-grw5s2pf	867	24	Hofmann	Hofmann	NNP
cord-256444-grw5s2pf	867	25	et	et	NNP
cord-256444-grw5s2pf	867	26	al	al	NNP
cord-256444-grw5s2pf	867	27	.	.	NNP
cord-256444-grw5s2pf	867	28	,	,	,
cord-256444-grw5s2pf	867	29	1990	1990	CD
cord-256444-grw5s2pf	867	30	;	;	:
cord-256444-grw5s2pf	867	31	Zhao	Zhao	NNP
cord-256444-grw5s2pf	867	32	et	et	NNP
cord-256444-grw5s2pf	867	33	al	al	NNP
cord-256444-grw5s2pf	867	34	.	.	NNP
cord-256444-grw5s2pf	867	35	,	,	,
cord-256444-grw5s2pf	867	36	1993	1993	CD
cord-256444-grw5s2pf	867	37	)	)	-RRB-
cord-256444-grw5s2pf	867	38	,	,	,
cord-256444-grw5s2pf	867	39	contain	contain	VBP
cord-256444-grw5s2pf	867	40	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	867	41	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	867	42	in	in	IN
cord-256444-grw5s2pf	867	43	the	the	DT
cord-256444-grw5s2pf	867	44	virion	virion	NN
cord-256444-grw5s2pf	867	45	,	,	,
cord-256444-grw5s2pf	867	46	probably	probably	RB
cord-256444-grw5s2pf	867	47	as	as	IN
cord-256444-grw5s2pf	867	48	a	a	DT
cord-256444-grw5s2pf	867	49	result	result	NN
cord-256444-grw5s2pf	867	50	of	of	IN
cord-256444-grw5s2pf	867	51	nonspecific	nonspecific	JJ
cord-256444-grw5s2pf	867	52	RNA	RNA	NNP
cord-256444-grw5s2pf	867	53	packaging	packaging	NN
cord-256444-grw5s2pf	867	54	,	,	,
cord-256444-grw5s2pf	867	55	it	-PRON-	PRP
cord-256444-grw5s2pf	867	56	was	be	VBD
cord-256444-grw5s2pf	867	57	proposed	propose	VBN
cord-256444-grw5s2pf	867	58	that	that	IN
cord-256444-grw5s2pf	867	59	these	these	DT
cord-256444-grw5s2pf	867	60	virion	virion	NN
cord-256444-grw5s2pf	867	61	-	-	HYPH
cord-256444-grw5s2pf	867	62	associated	associate	VBN
cord-256444-grw5s2pf	867	63	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	867	64	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	867	65	can	can	MD
cord-256444-grw5s2pf	867	66	be	be	VB
cord-256444-grw5s2pf	867	67	used	use	VBN
cord-256444-grw5s2pf	867	68	directly	directly	RB
cord-256444-grw5s2pf	867	69	as	as	IN
cord-256444-grw5s2pf	867	70	templates	template	NNS
cord-256444-grw5s2pf	867	71	for	for	IN
cord-256444-grw5s2pf	867	72	the	the	DT
cord-256444-grw5s2pf	867	73	synthesis	synthesis	NN
cord-256444-grw5s2pf	867	74	of	of	IN
cord-256444-grw5s2pf	867	75	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	867	76	negative	negative	JJ
cord-256444-grw5s2pf	867	77	-	-	HYPH
cord-256444-grw5s2pf	867	78	strand	strand	NN
cord-256444-grw5s2pf	867	79	RNAs	rna	NNS
cord-256444-grw5s2pf	867	80	,	,	,
cord-256444-grw5s2pf	867	81	which	which	WDT
cord-256444-grw5s2pf	867	82	,	,	,
cord-256444-grw5s2pf	867	83	in	in	IN
cord-256444-grw5s2pf	867	84	turn	turn	NN
cord-256444-grw5s2pf	867	85	,	,	,
cord-256444-grw5s2pf	867	86	serve	serve	VB
cord-256444-grw5s2pf	867	87	as	as	IN
cord-256444-grw5s2pf	867	88	templates	template	NNS
cord-256444-grw5s2pf	867	89	for	for	IN
cord-256444-grw5s2pf	867	90	the	the	DT
cord-256444-grw5s2pf	867	91	synthesis	synthesis	NN
cord-256444-grw5s2pf	867	92	of	of	IN
cord-256444-grw5s2pf	867	93	additional	additional	JJ
cord-256444-grw5s2pf	867	94	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	867	95	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	868	1	(	(	-LRB-
cord-256444-grw5s2pf	868	2	Sethna	Sethna	NNP
cord-256444-grw5s2pf	868	3	et	et	NNP
cord-256444-grw5s2pf	868	4	al	al	NNP
cord-256444-grw5s2pf	868	5	.	.	NNP
cord-256444-grw5s2pf	868	6	,	,	,
cord-256444-grw5s2pf	868	7	1989	1989	CD
cord-256444-grw5s2pf	868	8	)	)	-RRB-
cord-256444-grw5s2pf	868	9	.	.	.
cord-256444-grw5s2pf	869	1	This	this	DT
cord-256444-grw5s2pf	869	2	model	model	NN
cord-256444-grw5s2pf	869	3	may	may	MD
cord-256444-grw5s2pf	869	4	explain	explain	VB
cord-256444-grw5s2pf	869	5	the	the	DT
cord-256444-grw5s2pf	869	6	presence	presence	NN
cord-256444-grw5s2pf	869	7	of	of	IN
cord-256444-grw5s2pf	869	8	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	869	9	negative	negative	JJ
cord-256444-grw5s2pf	869	10	-	-	HYPH
cord-256444-grw5s2pf	869	11	strand	strand	NN
cord-256444-grw5s2pf	869	12	RNAs	rna	NNS
cord-256444-grw5s2pf	869	13	and	and	CC
cord-256444-grw5s2pf	869	14	RIs	RIs	NNPS
cord-256444-grw5s2pf	869	15	in	in	IN
cord-256444-grw5s2pf	869	16	the	the	DT
cord-256444-grw5s2pf	869	17	infected	infected	JJ
cord-256444-grw5s2pf	869	18	cells	cell	NNS
cord-256444-grw5s2pf	869	19	,	,	,
cord-256444-grw5s2pf	869	20	but	but	CC
cord-256444-grw5s2pf	869	21	it	-PRON-	PRP
cord-256444-grw5s2pf	869	22	can	can	MD
cord-256444-grw5s2pf	869	23	not	not	RB
cord-256444-grw5s2pf	869	24	explain	explain	VB
cord-256444-grw5s2pf	869	25	the	the	DT
cord-256444-grw5s2pf	869	26	genomiclength	genomiclength	NN
cord-256444-grw5s2pf	869	27	nature	nature	NN
cord-256444-grw5s2pf	869	28	of	of	IN
cord-256444-grw5s2pf	869	29	the	the	DT
cord-256444-grw5s2pf	869	30	W	w	NN
cord-256444-grw5s2pf	869	31	target	target	NN
cord-256444-grw5s2pf	869	32	sizes	size	NNS
cord-256444-grw5s2pf	869	33	for	for	IN
cord-256444-grw5s2pf	869	34	mRNA	mRNA	NNP
cord-256444-grw5s2pf	869	35	synthesis	synthesis	NN
cord-256444-grw5s2pf	869	36	early	early	RB
cord-256444-grw5s2pf	869	37	in	in	IN
cord-256444-grw5s2pf	869	38	infection	infection	NN
cord-256444-grw5s2pf	870	1	(	(	-LRB-
cord-256444-grw5s2pf	870	2	Yokomori	Yokomori	NNP
cord-256444-grw5s2pf	870	3	et	et	FW
cord-256444-grw5s2pf	870	4	al	al	NNP
cord-256444-grw5s2pf	870	5	.	.	NNP
cord-256444-grw5s2pf	870	6	,	,	,
cord-256444-grw5s2pf	870	7	1992b	1992b	CD
cord-256444-grw5s2pf	870	8	)	)	-RRB-
cord-256444-grw5s2pf	870	9	,	,	,
cord-256444-grw5s2pf	870	10	nor	nor	CC
cord-256444-grw5s2pf	870	11	can	can	MD
cord-256444-grw5s2pf	870	12	it	-PRON-	PRP
cord-256444-grw5s2pf	870	13	explain	explain	VB
cord-256444-grw5s2pf	870	14	how	how	WRB
cord-256444-grw5s2pf	870	15	leader	leader	NN
cord-256444-grw5s2pf	870	16	RNAs	rna	NNS
cord-256444-grw5s2pf	870	17	from	from	IN
cord-256444-grw5s2pf	870	18	different	different	JJ
cord-256444-grw5s2pf	870	19	virus	virus	NN
cord-256444-grw5s2pf	870	20	strains	strain	NNS
cord-256444-grw5s2pf	870	21	can	can	MD
cord-256444-grw5s2pf	870	22	be	be	VB
cord-256444-grw5s2pf	870	23	randomly	randomly	RB
cord-256444-grw5s2pf	870	24	incorporated	incorporate	VBN
cord-256444-grw5s2pf	870	25	into	into	IN
cord-256444-grw5s2pf	870	26	mRNAs	mrnas	CD
cord-256444-grw5s2pf	870	27	of	of	IN
cord-256444-grw5s2pf	870	28	a	a	DT
cord-256444-grw5s2pf	870	29	different	different	JJ
cord-256444-grw5s2pf	870	30	virus	virus	NN
cord-256444-grw5s2pf	870	31	.	.	.
cord-256444-grw5s2pf	871	1	Furthermore	furthermore	RB
cord-256444-grw5s2pf	871	2	,	,	,
cord-256444-grw5s2pf	871	3	the	the	DT
cord-256444-grw5s2pf	871	4	virion	virion	NN
cord-256444-grw5s2pf	871	5	-	-	HYPH
cord-256444-grw5s2pf	871	6	associated	associate	VBN
cord-256444-grw5s2pf	871	7	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	871	8	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	871	9	have	have	VBP
cord-256444-grw5s2pf	871	10	not	not	RB
cord-256444-grw5s2pf	871	11	been	be	VBN
cord-256444-grw5s2pf	871	12	detected	detect	VBN
cord-256444-grw5s2pf	871	13	in	in	IN
cord-256444-grw5s2pf	871	14	all	all	DT
cord-256444-grw5s2pf	871	15	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	871	16	species	specie	NNS
cord-256444-grw5s2pf	871	17	.	.	.
cord-256444-grw5s2pf	872	1	The	the	DT
cord-256444-grw5s2pf	872	2	available	available	JJ
cord-256444-grw5s2pf	872	3	data	datum	NNS
cord-256444-grw5s2pf	872	4	can	can	MD
cord-256444-grw5s2pf	872	5	not	not	RB
cord-256444-grw5s2pf	872	6	unequivocally	unequivocally	RB
cord-256444-grw5s2pf	872	7	rule	rule	VB
cord-256444-grw5s2pf	872	8	out	out	RP
cord-256444-grw5s2pf	872	9	any	any	DT
cord-256444-grw5s2pf	872	10	of	of	IN
cord-256444-grw5s2pf	872	11	the	the	DT
cord-256444-grw5s2pf	872	12	proposed	propose	VBN
cord-256444-grw5s2pf	872	13	transcription	transcription	NN
cord-256444-grw5s2pf	872	14	models	model	NNS
cord-256444-grw5s2pf	872	15	.	.	.
cord-256444-grw5s2pf	873	1	The	the	DT
cord-256444-grw5s2pf	873	2	primary	primary	JJ
cord-256444-grw5s2pf	873	3	difficulty	difficulty	NN
cord-256444-grw5s2pf	873	4	in	in	IN
cord-256444-grw5s2pf	873	5	experimental	experimental	JJ
cord-256444-grw5s2pf	873	6	analysis	analysis	NN
cord-256444-grw5s2pf	873	7	is	be	VBZ
cord-256444-grw5s2pf	873	8	that	that	IN
cord-256444-grw5s2pf	873	9	once	once	RB
cord-256444-grw5s2pf	873	10	the	the	DT
cord-256444-grw5s2pf	873	11	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	873	12	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	873	13	are	be	VBP
cord-256444-grw5s2pf	873	14	synthesized	synthesize	VBN
cord-256444-grw5s2pf	873	15	,	,	,
cord-256444-grw5s2pf	873	16	by	by	IN
cord-256444-grw5s2pf	873	17	whatever	whatever	WDT
cord-256444-grw5s2pf	873	18	mechanism	mechanism	NN
cord-256444-grw5s2pf	873	19	,	,	,
cord-256444-grw5s2pf	873	20	they	-PRON-	PRP
cord-256444-grw5s2pf	873	21	are	be	VBP
cord-256444-grw5s2pf	873	22	transcribed	transcribe	VBN
cord-256444-grw5s2pf	873	23	into	into	IN
cord-256444-grw5s2pf	873	24	negative	negative	JJ
cord-256444-grw5s2pf	873	25	-	-	HYPH
cord-256444-grw5s2pf	873	26	strand	strand	NN
cord-256444-grw5s2pf	873	27	RNAs	rna	NNS
cord-256444-grw5s2pf	873	28	because	because	IN
cord-256444-grw5s2pf	873	29	the	the	DT
cord-256444-grw5s2pf	873	30	cis	cis	NNP
cord-256444-grw5s2pf	873	31	-	-	HYPH
cord-256444-grw5s2pf	873	32	acting	act	VBG
cord-256444-grw5s2pf	873	33	signal	signal	NN
cord-256444-grw5s2pf	873	34	for	for	IN
cord-256444-grw5s2pf	873	35	negative	negative	JJ
cord-256444-grw5s2pf	873	36	-	-	HYPH
cord-256444-grw5s2pf	873	37	strand	strand	NN
cord-256444-grw5s2pf	873	38	RNA	RNA	NNP
cord-256444-grw5s2pf	873	39	synthesis	synthesis	NN
cord-256444-grw5s2pf	873	40	in	in	IN
cord-256444-grw5s2pf	873	41	MHV	MHV	NNP
cord-256444-grw5s2pf	873	42	resides	reside	VBZ
cord-256444-grw5s2pf	873	43	in	in	IN
cord-256444-grw5s2pf	873	44	the	the	DT
cord-256444-grw5s2pf	873	45	55	55	CD
cord-256444-grw5s2pf	873	46	nucleotides	nucleotide	NNS
cord-256444-grw5s2pf	873	47	at	at	IN
cord-256444-grw5s2pf	874	1	the	the	DT
cord-256444-grw5s2pf	874	2	3	3	CD
cord-256444-grw5s2pf	874	3	'	'	NN
cord-256444-grw5s2pf	874	4	end	end	NN
cord-256444-grw5s2pf	874	5	plus	plus	CC
cord-256444-grw5s2pf	874	6	poly(A	poly(a	JJ
cord-256444-grw5s2pf	874	7	)	)	-RRB-
cord-256444-grw5s2pf	875	1	(	(	-LRB-
cord-256444-grw5s2pf	875	2	Lin	Lin	NNP
cord-256444-grw5s2pf	875	3	et	et	NNP
cord-256444-grw5s2pf	875	4	al	al	NNP
cord-256444-grw5s2pf	875	5	.	.	NNP
cord-256444-grw5s2pf	875	6	,	,	,
cord-256444-grw5s2pf	875	7	1994	1994	CD
cord-256444-grw5s2pf	875	8	)	)	-RRB-
cord-256444-grw5s2pf	875	9	,	,	,
cord-256444-grw5s2pf	875	10	which	which	WDT
cord-256444-grw5s2pf	875	11	is	be	VBZ
cord-256444-grw5s2pf	875	12	present	present	JJ
cord-256444-grw5s2pf	875	13	in	in	IN
cord-256444-grw5s2pf	875	14	every	every	DT
cord-256444-grw5s2pf	875	15	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	875	16	RNA	RNA	NNP
cord-256444-grw5s2pf	875	17	.	.	.
cord-256444-grw5s2pf	876	1	Thus	thus	RB
cord-256444-grw5s2pf	876	2	,	,	,
cord-256444-grw5s2pf	876	3	it	-PRON-	PRP
cord-256444-grw5s2pf	876	4	is	be	VBZ
cord-256444-grw5s2pf	876	5	difficult	difficult	JJ
cord-256444-grw5s2pf	876	6	to	to	TO
cord-256444-grw5s2pf	876	7	separate	separate	VB
cord-256444-grw5s2pf	876	8	the	the	DT
cord-256444-grw5s2pf	876	9	primary	primary	JJ
cord-256444-grw5s2pf	876	10	and	and	CC
cord-256444-grw5s2pf	876	11	secondary	secondary	JJ
cord-256444-grw5s2pf	876	12	events	event	NNS
cord-256444-grw5s2pf	876	13	of	of	IN
cord-256444-grw5s2pf	876	14	transcription	transcription	NN
cord-256444-grw5s2pf	876	15	.	.	.
cord-256444-grw5s2pf	877	1	It	-PRON-	PRP
cord-256444-grw5s2pf	877	2	is	be	VBZ
cord-256444-grw5s2pf	877	3	possible	possible	JJ
cord-256444-grw5s2pf	877	4	that	that	IN
cord-256444-grw5s2pf	877	5	these	these	DT
cord-256444-grw5s2pf	877	6	transcription	transcription	NN
cord-256444-grw5s2pf	877	7	models	model	NNS
cord-256444-grw5s2pf	877	8	are	be	VBP
cord-256444-grw5s2pf	877	9	not	not	RB
cord-256444-grw5s2pf	877	10	mutually	mutually	RB
cord-256444-grw5s2pf	877	11	exclusive	exclusive	JJ
cord-256444-grw5s2pf	877	12	.	.	.
cord-256444-grw5s2pf	878	1	For	for	IN
cord-256444-grw5s2pf	878	2	example	example	NN
cord-256444-grw5s2pf	878	3	,	,	,
cord-256444-grw5s2pf	878	4	early	early	RB
cord-256444-grw5s2pf	878	5	in	in	IN
cord-256444-grw5s2pf	878	6	infection	infection	NN
cord-256444-grw5s2pf	878	7	,	,	,
cord-256444-grw5s2pf	878	8	a	a	DT
cord-256444-grw5s2pf	878	9	leader	leader	NN
cord-256444-grw5s2pf	878	10	-	-	HYPH
cord-256444-grw5s2pf	878	11	primed	prime	VBN
cord-256444-grw5s2pf	878	12	transcription	transcription	NN
cord-256444-grw5s2pf	878	13	or	or	CC
cord-256444-grw5s2pf	878	14	trans	trans	JJ
cord-256444-grw5s2pf	878	15	-	-	JJ
cord-256444-grw5s2pf	878	16	splicing	splicing	NN
cord-256444-grw5s2pf	878	17	mechanism	mechanism	NN
cord-256444-grw5s2pf	878	18	may	may	MD
cord-256444-grw5s2pf	878	19	operate	operate	VB
cord-256444-grw5s2pf	878	20	,	,	,
cord-256444-grw5s2pf	878	21	generating	generate	VBG
cord-256444-grw5s2pf	878	22	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	878	23	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	878	24	,	,	,
cord-256444-grw5s2pf	878	25	which	which	WDT
cord-256444-grw5s2pf	878	26	are	be	VBP
cord-256444-grw5s2pf	878	27	then	then	RB
cord-256444-grw5s2pf	878	28	amplified	amplify	VBN
cord-256444-grw5s2pf	878	29	into	into	IN
cord-256444-grw5s2pf	878	30	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	878	31	negative	negative	JJ
cord-256444-grw5s2pf	878	32	-	-	HYPH
cord-256444-grw5s2pf	878	33	strand	strand	NN
cord-256444-grw5s2pf	878	34	RNAs	rna	NNS
cord-256444-grw5s2pf	878	35	;	;	:
cord-256444-grw5s2pf	878	36	the	the	DT
cord-256444-grw5s2pf	878	37	latter	latter	JJ
cord-256444-grw5s2pf	878	38	serve	serve	VBP
cord-256444-grw5s2pf	878	39	as	as	IN
cord-256444-grw5s2pf	878	40	templates	template	NNS
cord-256444-grw5s2pf	878	41	for	for	IN
cord-256444-grw5s2pf	878	42	further	further	JJ
cord-256444-grw5s2pf	878	43	amplification	amplification	NN
cord-256444-grw5s2pf	878	44	of	of	IN
cord-256444-grw5s2pf	878	45	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	878	46	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	878	47	thereafter	thereafter	RB
cord-256444-grw5s2pf	878	48	.	.	.
cord-256444-grw5s2pf	879	1	The	the	DT
cord-256444-grw5s2pf	879	2	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	879	3	negative	negative	JJ
cord-256444-grw5s2pf	879	4	-	-	HYPH
cord-256444-grw5s2pf	879	5	strand	strand	NN
cord-256444-grw5s2pf	879	6	RNA	RNA	NNP
cord-256444-grw5s2pf	879	7	can	can	MD
cord-256444-grw5s2pf	879	8	be	be	VB
cord-256444-grw5s2pf	879	9	used	use	VBN
cord-256444-grw5s2pf	879	10	for	for	IN
cord-256444-grw5s2pf	879	11	either	either	CC
cord-256444-grw5s2pf	879	12	uninterrupted	uninterrupted	JJ
cord-256444-grw5s2pf	879	13	transcription	transcription	NN
cord-256444-grw5s2pf	879	14	or	or	CC
cord-256444-grw5s2pf	879	15	leader	leader	NN
cord-256444-grw5s2pf	879	16	-	-	HYPH
cord-256444-grw5s2pf	879	17	primed	prime	VBN
cord-256444-grw5s2pf	879	18	transcription	transcription	NN
cord-256444-grw5s2pf	879	19	to	to	TO
cord-256444-grw5s2pf	879	20	generate	generate	VB
cord-256444-grw5s2pf	879	21	positive	positive	JJ
cord-256444-grw5s2pf	879	22	-	-	HYPH
cord-256444-grw5s2pf	879	23	strand	strand	NN
cord-256444-grw5s2pf	879	24	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	879	25	RNAs	rna	NNS
cord-256444-grw5s2pf	879	26	.	.	.
cord-256444-grw5s2pf	880	1	A	a	DT
cord-256444-grw5s2pf	880	2	combination	combination	NN
cord-256444-grw5s2pf	880	3	of	of	IN
cord-256444-grw5s2pf	880	4	these	these	DT
cord-256444-grw5s2pf	880	5	models	model	NNS
cord-256444-grw5s2pf	880	6	would	would	MD
cord-256444-grw5s2pf	880	7	be	be	VB
cord-256444-grw5s2pf	880	8	consistent	consistent	JJ
cord-256444-grw5s2pf	880	9	with	with	IN
cord-256444-grw5s2pf	880	10	most	most	JJS
cord-256444-grw5s2pf	880	11	of	of	IN
cord-256444-grw5s2pf	880	12	the	the	DT
cord-256444-grw5s2pf	880	13	experimental	experimental	JJ
cord-256444-grw5s2pf	880	14	data	datum	NNS
cord-256444-grw5s2pf	880	15	.	.	.
cord-256444-grw5s2pf	881	1	This	this	DT
cord-256444-grw5s2pf	881	2	twostep	twostep	NN
cord-256444-grw5s2pf	881	3	model	model	NN
cord-256444-grw5s2pf	881	4	of	of	IN
cord-256444-grw5s2pf	881	5	primary	primary	JJ
cord-256444-grw5s2pf	881	6	and	and	CC
cord-256444-grw5s2pf	881	7	secondary	secondary	JJ
cord-256444-grw5s2pf	881	8	transcription	transcription	NN
cord-256444-grw5s2pf	881	9	(	(	-LRB-
cord-256444-grw5s2pf	881	10	Jeong	Jeong	NNP
cord-256444-grw5s2pf	881	11	and	and	CC
cord-256444-grw5s2pf	881	12	Makino	Makino	NNP
cord-256444-grw5s2pf	881	13	,	,	,
cord-256444-grw5s2pf	881	14	1992	1992	CD
cord-256444-grw5s2pf	881	15	)	)	-RRB-
cord-256444-grw5s2pf	881	16	may	may	MD
cord-256444-grw5s2pf	881	17	explain	explain	VB
cord-256444-grw5s2pf	881	18	the	the	DT
cord-256444-grw5s2pf	881	19	apparent	apparent	JJ
cord-256444-grw5s2pf	881	20	differences	difference	NNS
cord-256444-grw5s2pf	881	21	in	in	IN
cord-256444-grw5s2pf	881	22	the	the	DT
cord-256444-grw5s2pf	881	23	possible	possible	JJ
cord-256444-grw5s2pf	881	24	mechanism	mechanism	NN
cord-256444-grw5s2pf	881	25	of	of	IN
cord-256444-grw5s2pf	881	26	transcription	transcription	NN
cord-256444-grw5s2pf	881	27	between	between	IN
cord-256444-grw5s2pf	881	28	early	early	JJ
cord-256444-grw5s2pf	881	29	and	and	CC
cord-256444-grw5s2pf	881	30	late	late	JJ
cord-256444-grw5s2pf	881	31	stages	stage	NNS
cord-256444-grw5s2pf	881	32	of	of	IN
cord-256444-grw5s2pf	881	33	viral	viral	JJ
cord-256444-grw5s2pf	881	34	infection	infection	NN
cord-256444-grw5s2pf	881	35	.	.	.
cord-256444-grw5s2pf	882	1	Because	because	IN
cord-256444-grw5s2pf	882	2	of	of	IN
cord-256444-grw5s2pf	882	3	the	the	DT
cord-256444-grw5s2pf	882	4	large	large	JJ
cord-256444-grw5s2pf	882	5	size	size	NN
cord-256444-grw5s2pf	882	6	of	of	IN
cord-256444-grw5s2pf	882	7	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	882	8	RNA	RNA	NNP
cord-256444-grw5s2pf	882	9	,	,	,
cord-256444-grw5s2pf	882	10	no	no	DT
cord-256444-grw5s2pf	882	11	infectious	infectious	JJ
cord-256444-grw5s2pf	882	12	cDNA	cdna	NN
cord-256444-grw5s2pf	882	13	or	or	CC
cord-256444-grw5s2pf	882	14	RNA	RNA	NNP
cord-256444-grw5s2pf	882	15	clones	clone	NNS
cord-256444-grw5s2pf	882	16	are	be	VBP
cord-256444-grw5s2pf	882	17	now	now	RB
cord-256444-grw5s2pf	882	18	available	available	JJ
cord-256444-grw5s2pf	882	19	for	for	IN
cord-256444-grw5s2pf	882	20	reverse	reverse	JJ
cord-256444-grw5s2pf	882	21	genetics	genetics	NN
cord-256444-grw5s2pf	882	22	studies	study	NNS
cord-256444-grw5s2pf	882	23	.	.	.
cord-256444-grw5s2pf	883	1	This	this	DT
cord-256444-grw5s2pf	883	2	difficulty	difficulty	NN
cord-256444-grw5s2pf	883	3	has	have	VBZ
cord-256444-grw5s2pf	883	4	hampered	hamper	VBN
cord-256444-grw5s2pf	883	5	progress	progress	NN
cord-256444-grw5s2pf	883	6	in	in	IN
cord-256444-grw5s2pf	883	7	the	the	DT
cord-256444-grw5s2pf	883	8	study	study	NN
cord-256444-grw5s2pf	883	9	of	of	IN
cord-256444-grw5s2pf	883	10	the	the	DT
cord-256444-grw5s2pf	883	11	molecular	molecular	JJ
cord-256444-grw5s2pf	883	12	biology	biology	NN
cord-256444-grw5s2pf	883	13	of	of	IN
cord-256444-grw5s2pf	883	14	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	883	15	.	.	.
cord-256444-grw5s2pf	884	1	DI	DI	NNP
cord-256444-grw5s2pf	884	2	RNAs	rna	NNS
cord-256444-grw5s2pf	884	3	of	of	IN
cord-256444-grw5s2pf	884	4	several	several	JJ
cord-256444-grw5s2pf	884	5	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	884	6	(	(	-LRB-
cord-256444-grw5s2pf	884	7	see	see	VB
cord-256444-grw5s2pf	884	8	Section	section	NN
cord-256444-grw5s2pf	884	9	VI	VI	NNP
cord-256444-grw5s2pf	884	10	,	,	,
cord-256444-grw5s2pf	884	11	E	e	NN
cord-256444-grw5s2pf	884	12	)	)	-RRB-
cord-256444-grw5s2pf	884	13	have	have	VBP
cord-256444-grw5s2pf	884	14	been	be	VBN
cord-256444-grw5s2pf	884	15	molecularly	molecularly	RB
cord-256444-grw5s2pf	884	16	cloned	clone	VBN
cord-256444-grw5s2pf	884	17	and	and	CC
cord-256444-grw5s2pf	884	18	used	use	VBN
cord-256444-grw5s2pf	884	19	as	as	IN
cord-256444-grw5s2pf	884	20	a	a	DT
cord-256444-grw5s2pf	884	21	substitute	substitute	NN
cord-256444-grw5s2pf	884	22	for	for	IN
cord-256444-grw5s2pf	884	23	the	the	DT
cord-256444-grw5s2pf	884	24	genomic	genomic	JJ
cord-256444-grw5s2pf	884	25	RNA	RNA	NNP
cord-256444-grw5s2pf	884	26	to	to	TO
cord-256444-grw5s2pf	884	27	study	study	VB
cord-256444-grw5s2pf	884	28	the	the	DT
cord-256444-grw5s2pf	884	29	cis	cis	NNP
cord-256444-grw5s2pf	884	30	-	-	HYPH
cord-256444-grw5s2pf	884	31	and	and	CC
cord-256444-grw5s2pf	884	32	trans	trans	JJ
cord-256444-grw5s2pf	884	33	-	-	JJ
cord-256444-grw5s2pf	884	34	acting	acting	JJ
cord-256444-grw5s2pf	884	35	signals	signal	NNS
cord-256444-grw5s2pf	884	36	involved	involve	VBN
cord-256444-grw5s2pf	884	37	in	in	IN
cord-256444-grw5s2pf	884	38	viral	viral	JJ
cord-256444-grw5s2pf	884	39	RNA	RNA	NNP
cord-256444-grw5s2pf	884	40	synthesis	synthesis	NN
cord-256444-grw5s2pf	884	41	.	.	.
cord-256444-grw5s2pf	885	1	Although	although	IN
cord-256444-grw5s2pf	885	2	natural	natural	JJ
cord-256444-grw5s2pf	885	3	DI	DI	NNP
cord-256444-grw5s2pf	885	4	RNAs	rna	NNS
cord-256444-grw5s2pf	885	5	do	do	VBP
cord-256444-grw5s2pf	885	6	not	not	RB
cord-256444-grw5s2pf	885	7	contain	contain	VB
cord-256444-grw5s2pf	885	8	an	an	DT
cord-256444-grw5s2pf	885	9	mRNA	mrna	NN
cord-256444-grw5s2pf	885	10	start	start	NN
cord-256444-grw5s2pf	885	11	signal	signal	NN
cord-256444-grw5s2pf	885	12	and	and	CC
cord-256444-grw5s2pf	885	13	,	,	,
cord-256444-grw5s2pf	885	14	consequently	consequently	RB
cord-256444-grw5s2pf	885	15	,	,	,
cord-256444-grw5s2pf	885	16	can	can	MD
cord-256444-grw5s2pf	885	17	not	not	RB
cord-256444-grw5s2pf	885	18	transcribe	transcribe	VB
cord-256444-grw5s2pf	885	19	an	an	DT
cord-256444-grw5s2pf	885	20	mRNA	mrna	NN
cord-256444-grw5s2pf	885	21	,	,	,
cord-256444-grw5s2pf	885	22	the	the	DT
cord-256444-grw5s2pf	885	23	insertion	insertion	NN
cord-256444-grw5s2pf	885	24	of	of	IN
cord-256444-grw5s2pf	885	25	such	such	PDT
cord-256444-grw5s2pf	885	26	a	a	DT
cord-256444-grw5s2pf	885	27	signal	signal	NN
cord-256444-grw5s2pf	885	28	into	into	IN
cord-256444-grw5s2pf	885	29	the	the	DT
cord-256444-grw5s2pf	885	30	DI	DI	NNP
cord-256444-grw5s2pf	885	31	RNA	RNA	NNP
cord-256444-grw5s2pf	885	32	allows	allow	VBZ
cord-256444-grw5s2pf	885	33	an	an	DT
cord-256444-grw5s2pf	885	34	mRNA	mrna	NN
cord-256444-grw5s2pf	885	35	to	to	TO
cord-256444-grw5s2pf	885	36	be	be	VB
cord-256444-grw5s2pf	885	37	transcribed	transcribe	VBN
cord-256444-grw5s2pf	885	38	from	from	IN
cord-256444-grw5s2pf	885	39	the	the	DT
cord-256444-grw5s2pf	885	40	transfected	transfecte	VBN
cord-256444-grw5s2pf	885	41	DI	DI	NNP
cord-256444-grw5s2pf	885	42	RNA	RNA	NNP
cord-256444-grw5s2pf	885	43	in	in	IN
cord-256444-grw5s2pf	885	44	the	the	DT
cord-256444-grw5s2pf	885	45	virus	virus	NN
cord-256444-grw5s2pf	885	46	-	-	HYPH
cord-256444-grw5s2pf	885	47	infected	infect	VBN
cord-256444-grw5s2pf	885	48	cells	cell	NNS
cord-256444-grw5s2pf	885	49	,	,	,
cord-256444-grw5s2pf	885	50	thus	thus	RB
cord-256444-grw5s2pf	885	51	enabling	enable	VBG
cord-256444-grw5s2pf	885	52	studies	study	NNS
cord-256444-grw5s2pf	885	53	of	of	IN
cord-256444-grw5s2pf	885	54	the	the	DT
cord-256444-grw5s2pf	885	55	regulatory	regulatory	JJ
cord-256444-grw5s2pf	885	56	sequences	sequence	NNS
cord-256444-grw5s2pf	885	57	for	for	IN
cord-256444-grw5s2pf	885	58	transcription	transcription	NN
cord-256444-grw5s2pf	885	59	.	.	.
cord-256444-grw5s2pf	886	1	Following	follow	VBG
cord-256444-grw5s2pf	886	2	is	be	VBZ
cord-256444-grw5s2pf	886	3	a	a	DT
cord-256444-grw5s2pf	886	4	summary	summary	NN
cord-256444-grw5s2pf	886	5	of	of	IN
cord-256444-grw5s2pf	886	6	information	information	NN
cord-256444-grw5s2pf	886	7	that	that	WDT
cord-256444-grw5s2pf	886	8	has	have	VBZ
cord-256444-grw5s2pf	886	9	been	be	VBN
cord-256444-grw5s2pf	886	10	obtained	obtain	VBN
cord-256444-grw5s2pf	886	11	using	use	VBG
cord-256444-grw5s2pf	886	12	this	this	DT
cord-256444-grw5s2pf	886	13	approach	approach	NN
cord-256444-grw5s2pf	886	14	.	.	.
cord-256444-grw5s2pf	887	1	It	-PRON-	PRP
cord-256444-grw5s2pf	887	2	should	should	MD
cord-256444-grw5s2pf	887	3	be	be	VB
cord-256444-grw5s2pf	887	4	cautioned	caution	VBN
cord-256444-grw5s2pf	887	5	,	,	,
cord-256444-grw5s2pf	887	6	however	however	RB
cord-256444-grw5s2pf	887	7	,	,	,
cord-256444-grw5s2pf	887	8	that	that	IN
cord-256444-grw5s2pf	887	9	regulation	regulation	NN
cord-256444-grw5s2pf	887	10	of	of	IN
cord-256444-grw5s2pf	887	11	RNA	RNA	NNP
cord-256444-grw5s2pf	887	12	transcription	transcription	NN
cord-256444-grw5s2pf	887	13	probably	probably	RB
cord-256444-grw5s2pf	887	14	depends	depend	VBZ
cord-256444-grw5s2pf	887	15	on	on	IN
cord-256444-grw5s2pf	887	16	overall	overall	JJ
cord-256444-grw5s2pf	887	17	RNA	RNA	NNP
cord-256444-grw5s2pf	887	18	conformation	conformation	NN
cord-256444-grw5s2pf	887	19	and	and	CC
cord-256444-grw5s2pf	887	20	that	that	IN
cord-256444-grw5s2pf	887	21	the	the	DT
cord-256444-grw5s2pf	887	22	cis	cis	NNP
cord-256444-grw5s2pf	887	23	-	-	HYPH
cord-256444-grw5s2pf	887	24	acting	act	VBG
cord-256444-grw5s2pf	887	25	sequence	sequence	NN
cord-256444-grw5s2pf	887	26	required	require	VBN
cord-256444-grw5s2pf	887	27	for	for	IN
cord-256444-grw5s2pf	887	28	RNA	RNA	NNP
cord-256444-grw5s2pf	887	29	synthesis	synthesis	NN
cord-256444-grw5s2pf	887	30	very	very	RB
cord-256444-grw5s2pf	887	31	often	often	RB
cord-256444-grw5s2pf	887	32	varies	vary	VBZ
cord-256444-grw5s2pf	887	33	with	with	IN
cord-256444-grw5s2pf	887	34	the	the	DT
cord-256444-grw5s2pf	887	35	DI	DI	NNP
cord-256444-grw5s2pf	887	36	RNA	RNA	NNP
cord-256444-grw5s2pf	887	37	vector	vector	NN
cord-256444-grw5s2pf	887	38	used	use	VBN
cord-256444-grw5s2pf	887	39	;	;	:
cord-256444-grw5s2pf	887	40	therefore	therefore	RB
cord-256444-grw5s2pf	887	41	,	,	,
cord-256444-grw5s2pf	887	42	the	the	DT
cord-256444-grw5s2pf	887	43	results	result	NNS
cord-256444-grw5s2pf	887	44	obtained	obtain	VBN
cord-256444-grw5s2pf	887	45	from	from	IN
cord-256444-grw5s2pf	887	46	DI	DI	NNP
cord-256444-grw5s2pf	887	47	RNA	RNA	NNP
cord-256444-grw5s2pf	887	48	studies	study	NNS
cord-256444-grw5s2pf	887	49	may	may	MD
cord-256444-grw5s2pf	887	50	not	not	RB
cord-256444-grw5s2pf	887	51	be	be	VB
cord-256444-grw5s2pf	887	52	directly	directly	RB
cord-256444-grw5s2pf	887	53	applicable	applicable	JJ
cord-256444-grw5s2pf	887	54	to	to	IN
cord-256444-grw5s2pf	887	55	the	the	DT
cord-256444-grw5s2pf	887	56	viral	viral	JJ
cord-256444-grw5s2pf	887	57	genome	genome	NN
cord-256444-grw5s2pf	887	58	.	.	.
cord-256444-grw5s2pf	888	1	A	a	DT
cord-256444-grw5s2pf	888	2	full	full	JJ
cord-256444-grw5s2pf	888	3	understanding	understanding	NN
cord-256444-grw5s2pf	888	4	of	of	IN
cord-256444-grw5s2pf	888	5	the	the	DT
cord-256444-grw5s2pf	888	6	regulation	regulation	NN
cord-256444-grw5s2pf	888	7	of	of	IN
cord-256444-grw5s2pf	888	8	viral	viral	JJ
cord-256444-grw5s2pf	888	9	RNA	RNA	NNP
cord-256444-grw5s2pf	888	10	synthesis	synthesis	NN
cord-256444-grw5s2pf	888	11	still	still	RB
cord-256444-grw5s2pf	888	12	awaits	await	VBZ
cord-256444-grw5s2pf	888	13	the	the	DT
cord-256444-grw5s2pf	888	14	development	development	NN
cord-256444-grw5s2pf	888	15	of	of	IN
cord-256444-grw5s2pf	888	16	an	an	DT
cord-256444-grw5s2pf	888	17	infectious	infectious	JJ
cord-256444-grw5s2pf	888	18	cDNA	cdna	NN
cord-256444-grw5s2pf	888	19	clone	clone	NN
cord-256444-grw5s2pf	888	20	.	.	.
cord-256444-grw5s2pf	889	1	The	the	DT
cord-256444-grw5s2pf	889	2	following	follow	VBG
cord-256444-grw5s2pf	889	3	cis	cis	NN
cord-256444-grw5s2pf	889	4	-	-	HYPH
cord-256444-grw5s2pf	889	5	acting	act	VBG
cord-256444-grw5s2pf	889	6	signals	signal	NNS
cord-256444-grw5s2pf	889	7	for	for	IN
cord-256444-grw5s2pf	889	8	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	889	9	RNA	RNA	NNP
cord-256444-grw5s2pf	889	10	transcription	transcription	NN
cord-256444-grw5s2pf	889	11	have	have	VBP
cord-256444-grw5s2pf	889	12	been	be	VBN
cord-256444-grw5s2pf	889	13	determined	determine	VBN
cord-256444-grw5s2pf	889	14	primarily	primarily	RB
cord-256444-grw5s2pf	889	15	from	from	IN
cord-256444-grw5s2pf	889	16	MHV	MHV	NNP
cord-256444-grw5s2pf	889	17	DI	DI	NNP
cord-256444-grw5s2pf	889	18	RNA	RNA	NNP
cord-256444-grw5s2pf	889	19	studies	study	NNS
cord-256444-grw5s2pf	889	20	(	(	-LRB-
cord-256444-grw5s2pf	889	21	with	with	IN
cord-256444-grw5s2pf	889	22	some	some	DT
cord-256444-grw5s2pf	889	23	from	from	IN
cord-256444-grw5s2pf	889	24	BCV	BCV	NNP
cord-256444-grw5s2pf	889	25	DI	DI	NNP
cord-256444-grw5s2pf	889	26	)	)	-RRB-
cord-256444-grw5s2pf	890	1	(	(	-LRB-
cord-256444-grw5s2pf	890	2	Fig	Fig	NNP
cord-256444-grw5s2pf	890	3	.	.	.
cord-256444-grw5s2pf	890	4	9	9	CD
cord-256444-grw5s2pf	890	5	)	)	-RRB-
cord-256444-grw5s2pf	890	6	.	.	.
cord-256444-grw5s2pf	891	1	a.	a.	NN
cord-256444-grw5s2pf	891	2	IG	IG	NNP
cord-256444-grw5s2pf	891	3	Sequence	Sequence	NNP
cord-256444-grw5s2pf	891	4	.	.	.
cord-256444-grw5s2pf	892	1	The	the	DT
cord-256444-grw5s2pf	892	2	IG	IG	NNP
cord-256444-grw5s2pf	892	3	sequence	sequence	NN
cord-256444-grw5s2pf	892	4	can	can	MD
cord-256444-grw5s2pf	892	5	be	be	VB
cord-256444-grw5s2pf	892	6	considered	consider	VBN
cord-256444-grw5s2pf	892	7	to	to	TO
cord-256444-grw5s2pf	892	8	be	be	VB
cord-256444-grw5s2pf	892	9	the	the	DT
cord-256444-grw5s2pf	892	10	promoter	promoter	NN
cord-256444-grw5s2pf	892	11	element	element	NN
cord-256444-grw5s2pf	892	12	for	for	IN
cord-256444-grw5s2pf	892	13	transcription	transcription	NN
cord-256444-grw5s2pf	892	14	.	.	.
cord-256444-grw5s2pf	893	1	It	-PRON-	PRP
cord-256444-grw5s2pf	893	2	also	also	RB
cord-256444-grw5s2pf	893	3	serves	serve	VBZ
cord-256444-grw5s2pf	893	4	as	as	IN
cord-256444-grw5s2pf	893	5	the	the	DT
cord-256444-grw5s2pf	893	6	mRNA	mRNA	NNP
cord-256444-grw5s2pf	893	7	start	start	NN
cord-256444-grw5s2pf	893	8	site	site	NN
cord-256444-grw5s2pf	893	9	and	and	CC
cord-256444-grw5s2pf	893	10	the	the	DT
cord-256444-grw5s2pf	893	11	site	site	NN
cord-256444-grw5s2pf	893	12	of	of	IN
cord-256444-grw5s2pf	893	13	fusion	fusion	NN
cord-256444-grw5s2pf	893	14	between	between	IN
cord-256444-grw5s2pf	893	15	the	the	DT
cord-256444-grw5s2pf	893	16	leader	leader	NN
cord-256444-grw5s2pf	893	17	RNA	RNA	NNP
cord-256444-grw5s2pf	893	18	and	and	CC
cord-256444-grw5s2pf	893	19	body	body	NN
cord-256444-grw5s2pf	893	20	sequence	sequence	NN
cord-256444-grw5s2pf	893	21	of	of	IN
cord-256444-grw5s2pf	893	22	mRNAs	mrnas	CD
cord-256444-grw5s2pf	893	23	.	.	.
cord-256444-grw5s2pf	894	1	A	a	DT
cord-256444-grw5s2pf	894	2	seven	seven	CD
cord-256444-grw5s2pf	894	3	-	-	HYPH
cord-256444-grw5s2pf	894	4	nucleotide	nucleotide	JJ
cord-256444-grw5s2pf	894	5	core	core	NN
cord-256444-grw5s2pf	894	6	sequence	sequence	NN
cord-256444-grw5s2pf	894	7	,	,	,
cord-256444-grw5s2pf	894	8	UCUAMC	UCUAMC	NNP
cord-256444-grw5s2pf	894	9	,	,	,
cord-256444-grw5s2pf	894	10	is	be	VBZ
cord-256444-grw5s2pf	894	11	sufficient	sufficient	JJ
cord-256444-grw5s2pf	894	12	to	to	TO
cord-256444-grw5s2pf	894	13	initiate	initiate	VB
cord-256444-grw5s2pf	894	14	mRNA	mrna	NN
cord-256444-grw5s2pf	894	15	synthesis	synthesis	NN
cord-256444-grw5s2pf	894	16	(	(	-LRB-
cord-256444-grw5s2pf	894	17	Makino	Makino	NNP
cord-256444-grw5s2pf	894	18	et	et	NNP
cord-256444-grw5s2pf	894	19	al	al	NNP
cord-256444-grw5s2pf	894	20	.	.	NNP
cord-256444-grw5s2pf	894	21	,	,	,
cord-256444-grw5s2pf	894	22	1991	1991	CD
cord-256444-grw5s2pf	894	23	)	)	-RRB-
cord-256444-grw5s2pf	894	24	.	.	.
cord-256444-grw5s2pf	895	1	Extensive	extensive	JJ
cord-256444-grw5s2pf	895	2	site	site	NN
cord-256444-grw5s2pf	895	3	-	-	HYPH
cord-256444-grw5s2pf	895	4	specific	specific	JJ
cord-256444-grw5s2pf	895	5	mutagenesis	mutagenesis	NN
cord-256444-grw5s2pf	895	6	studies	study	NNS
cord-256444-grw5s2pf	895	7	have	have	VBP
cord-256444-grw5s2pf	895	8	shown	show	VBN
cord-256444-grw5s2pf	895	9	that	that	IN
cord-256444-grw5s2pf	895	10	most	most	JJS
cord-256444-grw5s2pf	895	11	of	of	IN
cord-256444-grw5s2pf	895	12	the	the	DT
cord-256444-grw5s2pf	895	13	single	single	JJ
cord-256444-grw5s2pf	895	14	-	-	HYPH
cord-256444-grw5s2pf	895	15	nucleotide	nucleotide	NN
cord-256444-grw5s2pf	895	16	mutations	mutation	NNS
cord-256444-grw5s2pf	895	17	within	within	IN
cord-256444-grw5s2pf	895	18	this	this	DT
cord-256444-grw5s2pf	895	19	core	core	NN
cord-256444-grw5s2pf	895	20	sequence	sequence	NN
cord-256444-grw5s2pf	895	21	could	could	MD
cord-256444-grw5s2pf	895	22	be	be	VB
cord-256444-grw5s2pf	895	23	tolerated	tolerate	VBN
cord-256444-grw5s2pf	895	24	,	,	,
cord-256444-grw5s2pf	895	25	although	although	IN
cord-256444-grw5s2pf	895	26	the	the	DT
cord-256444-grw5s2pf	895	27	transcription	transcription	NN
cord-256444-grw5s2pf	895	28	efficiency	efficiency	NN
cord-256444-grw5s2pf	895	29	of	of	IN
cord-256444-grw5s2pf	895	30	some	some	DT
cord-256444-grw5s2pf	895	31	of	of	IN
cord-256444-grw5s2pf	895	32	these	these	DT
cord-256444-grw5s2pf	895	33	mutants	mutant	NNS
cord-256444-grw5s2pf	895	34	was	be	VBD
cord-256444-grw5s2pf	895	35	lower	low	JJR
cord-256444-grw5s2pf	895	36	(	(	-LRB-
cord-256444-grw5s2pf	895	37	Joo	Joo	NNP
cord-256444-grw5s2pf	895	38	and	and	CC
cord-256444-grw5s2pf	895	39	Makino	Makino	NNP
cord-256444-grw5s2pf	895	40	,	,	,
cord-256444-grw5s2pf	895	41	1992	1992	CD
cord-256444-grw5s2pf	895	42	;	;	:
cord-256444-grw5s2pf	895	43	van	van	NNP
cord-256444-grw5s2pf	895	44	der	der	NNP
cord-256444-grw5s2pf	895	45	Most	Most	NNP
cord-256444-grw5s2pf	895	46	et	et	NNP
cord-256444-grw5s2pf	895	47	al	al	NNP
cord-256444-grw5s2pf	895	48	.	.	NNP
cord-256444-grw5s2pf	895	49	,	,	,
cord-256444-grw5s2pf	895	50	1994	1994	CD
cord-256444-grw5s2pf	895	51	)	)	-RRB-
cord-256444-grw5s2pf	895	52	.	.	.
cord-256444-grw5s2pf	896	1	These	these	DT
cord-256444-grw5s2pf	896	2	seven	seven	CD
cord-256444-grw5s2pf	896	3	nucleotides	nucleotide	NNS
cord-256444-grw5s2pf	896	4	represent	represent	VBP
cord-256444-grw5s2pf	896	5	the	the	DT
cord-256444-grw5s2pf	896	6	minimum	minimum	JJ
cord-256444-grw5s2pf	896	7	promoter	promoter	NN
cord-256444-grw5s2pf	896	8	;	;	:
cord-256444-grw5s2pf	896	9	deletion	deletion	NN
cord-256444-grw5s2pf	896	10	of	of	IN
cord-256444-grw5s2pf	896	11	a	a	DT
cord-256444-grw5s2pf	896	12	nucleotide	nucleotide	JJ
cord-256444-grw5s2pf	896	13	results	result	NNS
cord-256444-grw5s2pf	896	14	in	in	IN
cord-256444-grw5s2pf	896	15	complete	complete	JJ
cord-256444-grw5s2pf	896	16	ablation	ablation	NN
cord-256444-grw5s2pf	896	17	of	of	IN
cord-256444-grw5s2pf	896	18	mRNA	mRNA	NNP
cord-256444-grw5s2pf	896	19	transcription	transcription	NN
cord-256444-grw5s2pf	896	20	.	.	.
cord-256444-grw5s2pf	897	1	The	the	DT
cord-256444-grw5s2pf	897	2	effects	effect	NNS
cord-256444-grw5s2pf	897	3	of	of	IN
cord-256444-grw5s2pf	897	4	the	the	DT
cord-256444-grw5s2pf	897	5	sequences	sequence	NNS
cord-256444-grw5s2pf	897	6	near	near	IN
cord-256444-grw5s2pf	897	7	the	the	DT
cord-256444-grw5s2pf	897	8	promoter	promoter	NN
cord-256444-grw5s2pf	897	9	on	on	IN
cord-256444-grw5s2pf	897	10	transcription	transcription	NN
cord-256444-grw5s2pf	897	11	are	be	VBP
cord-256444-grw5s2pf	897	12	contradictory	contradictory	JJ
cord-256444-grw5s2pf	897	13	:	:	:
cord-256444-grw5s2pf	897	14	in	in	IN
cord-256444-grw5s2pf	897	15	certain	certain	JJ
cord-256444-grw5s2pf	897	16	situa-	situa-	NNS
cord-256444-grw5s2pf	897	17	tions	tion	NNS
cord-256444-grw5s2pf	897	18	,	,	,
cord-256444-grw5s2pf	897	19	the	the	DT
cord-256444-grw5s2pf	897	20	nature	nature	NN
cord-256444-grw5s2pf	897	21	of	of	IN
cord-256444-grw5s2pf	897	22	the	the	DT
cord-256444-grw5s2pf	897	23	neighboring	neighboring	NN
cord-256444-grw5s2pf	897	24	sequences	sequence	NNS
cord-256444-grw5s2pf	897	25	did	do	VBD
cord-256444-grw5s2pf	897	26	not	not	RB
cord-256444-grw5s2pf	897	27	affect	affect	VB
cord-256444-grw5s2pf	897	28	transcription	transcription	NN
cord-256444-grw5s2pf	897	29	(	(	-LRB-
cord-256444-grw5s2pf	897	30	Makino	Makino	NNP
cord-256444-grw5s2pf	897	31	and	and	CC
cord-256444-grw5s2pf	897	32	Joo	Joo	NNP
cord-256444-grw5s2pf	897	33	,	,	,
cord-256444-grw5s2pf	897	34	19931	19931	CD
cord-256444-grw5s2pf	897	35	,	,	,
cord-256444-grw5s2pf	897	36	but	but	CC
cord-256444-grw5s2pf	897	37	under	under	IN
cord-256444-grw5s2pf	897	38	other	other	JJ
cord-256444-grw5s2pf	897	39	circumstances	circumstance	NNS
cord-256444-grw5s2pf	897	40	,	,	,
cord-256444-grw5s2pf	897	41	it	-PRON-	PRP
cord-256444-grw5s2pf	897	42	did	do	VBD
cord-256444-grw5s2pf	897	43	(	(	-LRB-
cord-256444-grw5s2pf	897	44	Jeong	Jeong	NNP
cord-256444-grw5s2pf	897	45	et	et	NNP
cord-256444-grw5s2pf	897	46	al	al	NNP
cord-256444-grw5s2pf	897	47	.	.	NNP
cord-256444-grw5s2pf	897	48	,	,	,
cord-256444-grw5s2pf	897	49	1996	1996	CD
cord-256444-grw5s2pf	897	50	)	)	-RRB-
cord-256444-grw5s2pf	897	51	.	.	.
cord-256444-grw5s2pf	898	1	Thus	thus	RB
cord-256444-grw5s2pf	898	2	,	,	,
cord-256444-grw5s2pf	898	3	the	the	DT
cord-256444-grw5s2pf	898	4	strength	strength	NN
cord-256444-grw5s2pf	898	5	of	of	IN
cord-256444-grw5s2pf	898	6	the	the	DT
cord-256444-grw5s2pf	898	7	promoter	promoter	NN
cord-256444-grw5s2pf	898	8	appears	appear	VBZ
cord-256444-grw5s2pf	898	9	to	to	TO
cord-256444-grw5s2pf	898	10	depend	depend	VB
cord-256444-grw5s2pf	898	11	on	on	IN
cord-256444-grw5s2pf	898	12	the	the	DT
cord-256444-grw5s2pf	898	13	context	context	NN
cord-256444-grw5s2pf	898	14	of	of	IN
cord-256444-grw5s2pf	898	15	the	the	DT
cord-256444-grw5s2pf	898	16	overall	overall	JJ
cord-256444-grw5s2pf	898	17	RNA	RNA	NNP
cord-256444-grw5s2pf	898	18	sequence	sequence	NN
cord-256444-grw5s2pf	898	19	and	and	CC
cord-256444-grw5s2pf	898	20	structure	structure	NN
cord-256444-grw5s2pf	898	21	.	.	.
cord-256444-grw5s2pf	899	1	The	the	DT
cord-256444-grw5s2pf	899	2	relative	relative	JJ
cord-256444-grw5s2pf	899	3	flexibility	flexibility	NN
cord-256444-grw5s2pf	899	4	of	of	IN
cord-256444-grw5s2pf	899	5	sequence	sequence	NN
cord-256444-grw5s2pf	899	6	requirement	requirement	NN
cord-256444-grw5s2pf	899	7	of	of	IN
cord-256444-grw5s2pf	899	8	the	the	DT
cord-256444-grw5s2pf	899	9	promoter	promoter	NN
cord-256444-grw5s2pf	899	10	sequence	sequence	NN
cord-256444-grw5s2pf	899	11	in	in	IN
cord-256444-grw5s2pf	899	12	the	the	DT
cord-256444-grw5s2pf	899	13	DI	DI	NNP
cord-256444-grw5s2pf	899	14	RNA	RNA	NNP
cord-256444-grw5s2pf	899	15	system	system	NN
cord-256444-grw5s2pf	899	16	appears	appear	VBZ
cord-256444-grw5s2pf	899	17	to	to	TO
cord-256444-grw5s2pf	899	18	differ	differ	VB
cord-256444-grw5s2pf	899	19	significantly	significantly	RB
cord-256444-grw5s2pf	899	20	from	from	IN
cord-256444-grw5s2pf	899	21	that	that	DT
cord-256444-grw5s2pf	899	22	seen	see	VBN
cord-256444-grw5s2pf	899	23	in	in	IN
cord-256444-grw5s2pf	899	24	the	the	DT
cord-256444-grw5s2pf	899	25	viral	viral	JJ
cord-256444-grw5s2pf	899	26	genomic	genomic	JJ
cord-256444-grw5s2pf	899	27	RNA	RNA	NNP
cord-256444-grw5s2pf	899	28	.	.	.
cord-256444-grw5s2pf	900	1	In	in	IN
cord-256444-grw5s2pf	900	2	the	the	DT
cord-256444-grw5s2pf	900	3	MHV	MHV	NNP
cord-256444-grw5s2pf	900	4	genome	genome	NN
cord-256444-grw5s2pf	900	5	,	,	,
cord-256444-grw5s2pf	900	6	there	there	EX
cord-256444-grw5s2pf	900	7	are	be	VBP
cord-256444-grw5s2pf	900	8	more	more	JJR
cord-256444-grw5s2pf	900	9	than	than	IN
cord-256444-grw5s2pf	900	10	20	20	CD
cord-256444-grw5s2pf	900	11	stretches	stretch	NNS
cord-256444-grw5s2pf	900	12	of	of	IN
cord-256444-grw5s2pf	900	13	sequence	sequence	NN
cord-256444-grw5s2pf	900	14	resembling	resemble	VBG
cord-256444-grw5s2pf	900	15	the	the	DT
cord-256444-grw5s2pf	900	16	UCUAAAC	UCUAAAC	NNP
cord-256444-grw5s2pf	900	17	sequence	sequence	NN
cord-256444-grw5s2pf	900	18	,	,	,
cord-256444-grw5s2pf	900	19	in	in	IN
cord-256444-grw5s2pf	900	20	addition	addition	NN
cord-256444-grw5s2pf	900	21	to	to	IN
cord-256444-grw5s2pf	900	22	the	the	DT
cord-256444-grw5s2pf	900	23	six	six	CD
cord-256444-grw5s2pf	900	24	promoters	promoter	NNS
cord-256444-grw5s2pf	900	25	for	for	IN
cord-256444-grw5s2pf	900	26	the	the	DT
cord-256444-grw5s2pf	900	27	known	know	VBN
cord-256444-grw5s2pf	900	28	subgenomic	subgenomic	NN
cord-256444-grw5s2pf	900	29	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	901	1	(	(	-LRB-
cord-256444-grw5s2pf	901	2	Joo	Joo	NNP
cord-256444-grw5s2pf	901	3	and	and	CC
cord-256444-grw5s2pf	901	4	Makino	Makino	NNP
cord-256444-grw5s2pf	901	5	,	,	,
cord-256444-grw5s2pf	901	6	1992	1992	CD
cord-256444-grw5s2pf	901	7	)	)	-RRB-
cord-256444-grw5s2pf	901	8	.	.	.
cord-256444-grw5s2pf	902	1	Yet	yet	RB
cord-256444-grw5s2pf	902	2	,	,	,
cord-256444-grw5s2pf	902	3	most	most	JJS
cord-256444-grw5s2pf	902	4	of	of	IN
cord-256444-grw5s2pf	902	5	these	these	DT
cord-256444-grw5s2pf	902	6	did	do	VBD
cord-256444-grw5s2pf	902	7	not	not	RB
cord-256444-grw5s2pf	902	8	promote	promote	VB
cord-256444-grw5s2pf	902	9	mRNA	mrna	NN
cord-256444-grw5s2pf	902	10	synthesis	synthesis	NN
cord-256444-grw5s2pf	902	11	from	from	IN
cord-256444-grw5s2pf	902	12	the	the	DT
cord-256444-grw5s2pf	902	13	viral	viral	JJ
cord-256444-grw5s2pf	902	14	RNA	RNA	NNP
cord-256444-grw5s2pf	902	15	genome	genome	NN
cord-256444-grw5s2pf	902	16	to	to	IN
cord-256444-grw5s2pf	902	17	any	any	DT
cord-256444-grw5s2pf	902	18	appreciable	appreciable	JJ
cord-256444-grw5s2pf	902	19	extent	extent	NN
cord-256444-grw5s2pf	902	20	,	,	,
cord-256444-grw5s2pf	902	21	in	in	IN
cord-256444-grw5s2pf	902	22	contrast	contrast	NN
cord-256444-grw5s2pf	902	23	to	to	IN
cord-256444-grw5s2pf	902	24	their	-PRON-	PRP$
cord-256444-grw5s2pf	902	25	ability	ability	NN
cord-256444-grw5s2pf	902	26	to	to	TO
cord-256444-grw5s2pf	902	27	promote	promote	VB
cord-256444-grw5s2pf	902	28	transcription	transcription	NN
cord-256444-grw5s2pf	902	29	in	in	IN
cord-256444-grw5s2pf	902	30	the	the	DT
cord-256444-grw5s2pf	902	31	DI	DI	NNP
cord-256444-grw5s2pf	902	32	RNA	RNA	NNP
cord-256444-grw5s2pf	902	33	vector	vector	NN
cord-256444-grw5s2pf	902	34	system	system	NN
cord-256444-grw5s2pf	902	35	(	(	-LRB-
cord-256444-grw5s2pf	902	36	Joo	Joo	NNP
cord-256444-grw5s2pf	902	37	and	and	CC
cord-256444-grw5s2pf	902	38	Makino	Makino	NNP
cord-256444-grw5s2pf	902	39	,	,	,
cord-256444-grw5s2pf	902	40	1992	1992	CD
cord-256444-grw5s2pf	902	41	)	)	-RRB-
cord-256444-grw5s2pf	902	42	.	.	.
cord-256444-grw5s2pf	903	1	In	in	IN
cord-256444-grw5s2pf	903	2	the	the	DT
cord-256444-grw5s2pf	903	3	viral	viral	JJ
cord-256444-grw5s2pf	903	4	genome	genome	NN
cord-256444-grw5s2pf	903	5	,	,	,
cord-256444-grw5s2pf	903	6	the	the	DT
cord-256444-grw5s2pf	903	7	single	single	JJ
cord-256444-grw5s2pf	903	8	-	-	HYPH
cord-256444-grw5s2pf	903	9	nucleotide	nucleotide	JJ
cord-256444-grw5s2pf	903	10	substitution	substitution	NN
cord-256444-grw5s2pf	903	11	of	of	IN
cord-256444-grw5s2pf	903	12	a	a	DT
cord-256444-grw5s2pf	903	13	G	g	NN
cord-256444-grw5s2pf	903	14	residue	residue	NN
cord-256444-grw5s2pf	903	15	in	in	IN
cord-256444-grw5s2pf	903	16	the	the	DT
cord-256444-grw5s2pf	903	17	core	core	NN
cord-256444-grw5s2pf	903	18	promoter	promoter	NN
cord-256444-grw5s2pf	903	19	sequence	sequence	NN
cord-256444-grw5s2pf	903	20	completely	completely	RB
cord-256444-grw5s2pf	903	21	abolished	abolish	VBD
cord-256444-grw5s2pf	903	22	mRNA	mrna	NN
cord-256444-grw5s2pf	903	23	synthesis	synthesis	NN
cord-256444-grw5s2pf	903	24	(	(	-LRB-
cord-256444-grw5s2pf	903	25	Shieh	Shieh	NNP
cord-256444-grw5s2pf	903	26	et	et	NNP
cord-256444-grw5s2pf	903	27	al	al	NNP
cord-256444-grw5s2pf	903	28	.	.	NNP
cord-256444-grw5s2pf	903	29	,	,	,
cord-256444-grw5s2pf	903	30	19891	19891	CD
cord-256444-grw5s2pf	903	31	,	,	,
cord-256444-grw5s2pf	903	32	whereas	whereas	IN
cord-256444-grw5s2pf	903	33	this	this	DT
cord-256444-grw5s2pf	903	34	is	be	VBZ
cord-256444-grw5s2pf	903	35	tolerated	tolerate	VBN
cord-256444-grw5s2pf	903	36	in	in	IN
cord-256444-grw5s2pf	903	37	the	the	DT
cord-256444-grw5s2pf	903	38	DI	DI	NNP
cord-256444-grw5s2pf	903	39	RNA	RNA	NNP
cord-256444-grw5s2pf	903	40	(	(	-LRB-
cord-256444-grw5s2pf	903	41	Joo	Joo	NNP
cord-256444-grw5s2pf	903	42	and	and	CC
cord-256444-grw5s2pf	903	43	Makino	Makino	NNP
cord-256444-grw5s2pf	903	44	,	,	,
cord-256444-grw5s2pf	903	45	1992	1992	CD
cord-256444-grw5s2pf	903	46	)	)	-RRB-
cord-256444-grw5s2pf	903	47	.	.	.
cord-256444-grw5s2pf	904	1	Thus	thus	RB
cord-256444-grw5s2pf	904	2	,	,	,
cord-256444-grw5s2pf	904	3	there	there	EX
cord-256444-grw5s2pf	904	4	appear	appear	VBP
cord-256444-grw5s2pf	904	5	to	to	TO
cord-256444-grw5s2pf	904	6	be	be	VB
cord-256444-grw5s2pf	904	7	significant	significant	JJ
cord-256444-grw5s2pf	904	8	differences	difference	NNS
cord-256444-grw5s2pf	904	9	between	between	IN
cord-256444-grw5s2pf	904	10	the	the	DT
cord-256444-grw5s2pf	904	11	sequence	sequence	NN
cord-256444-grw5s2pf	904	12	requirement	requirement	NN
cord-256444-grw5s2pf	904	13	for	for	IN
cord-256444-grw5s2pf	904	14	mRNA	mRNA	NNP
cord-256444-grw5s2pf	904	15	synthesis	synthesis	NN
cord-256444-grw5s2pf	904	16	in	in	IN
cord-256444-grw5s2pf	904	17	the	the	DT
cord-256444-grw5s2pf	904	18	DI	DI	NNP
cord-256444-grw5s2pf	904	19	RNA	RNA	NNP
cord-256444-grw5s2pf	904	20	and	and	CC
cord-256444-grw5s2pf	904	21	in	in	IN
cord-256444-grw5s2pf	904	22	the	the	DT
cord-256444-grw5s2pf	904	23	natural	natural	JJ
cord-256444-grw5s2pf	904	24	viral	viral	JJ
cord-256444-grw5s2pf	904	25	genomic	genomic	JJ
cord-256444-grw5s2pf	904	26	RNA	RNA	NNP
cord-256444-grw5s2pf	904	27	.	.	.
cord-256444-grw5s2pf	905	1	When	when	WRB
cord-256444-grw5s2pf	905	2	there	there	EX
cord-256444-grw5s2pf	905	3	are	be	VBP
cord-256444-grw5s2pf	905	4	multiple	multiple	JJ
cord-256444-grw5s2pf	905	5	IG	ig	NN
cord-256444-grw5s2pf	905	6	sequences	sequence	NNS
cord-256444-grw5s2pf	905	7	in	in	IN
cord-256444-grw5s2pf	905	8	the	the	DT
cord-256444-grw5s2pf	905	9	DI	DI	NNP
cord-256444-grw5s2pf	905	10	RNA	RNA	NNP
cord-256444-grw5s2pf	905	11	,	,	,
cord-256444-grw5s2pf	905	12	the	the	DT
cord-256444-grw5s2pf	905	13	order	order	NN
cord-256444-grw5s2pf	905	14	of	of	IN
cord-256444-grw5s2pf	905	15	the	the	DT
cord-256444-grw5s2pf	905	16	IG	IG	NNP
cord-256444-grw5s2pf	905	17	sequences	sequence	NNS
cord-256444-grw5s2pf	905	18	may	may	MD
cord-256444-grw5s2pf	905	19	influence	influence	VB
cord-256444-grw5s2pf	905	20	transcriptional	transcriptional	JJ
cord-256444-grw5s2pf	905	21	efficiency	efficiency	NN
cord-256444-grw5s2pf	905	22	.	.	.
cord-256444-grw5s2pf	906	1	An	an	DT
cord-256444-grw5s2pf	906	2	IG	ig	NN
cord-256444-grw5s2pf	906	3	located	locate	VBN
cord-256444-grw5s2pf	906	4	at	at	IN
cord-256444-grw5s2pf	906	5	the	the	DT
cord-256444-grw5s2pf	906	6	3	3	CD
cord-256444-grw5s2pf	906	7	'	'	NN
cord-256444-grw5s2pf	906	8	end	end	NN
cord-256444-grw5s2pf	906	9	generally	generally	RB
cord-256444-grw5s2pf	906	10	has	have	VBZ
cord-256444-grw5s2pf	906	11	an	an	DT
cord-256444-grw5s2pf	906	12	advantage	advantage	NN
cord-256444-grw5s2pf	906	13	in	in	IN
cord-256444-grw5s2pf	906	14	initiating	initiate	VBG
cord-256444-grw5s2pf	906	15	mRNA	mRNA	NNP
cord-256444-grw5s2pf	906	16	synthesis	synthesis	NN
cord-256444-grw5s2pf	906	17	(	(	-LRB-
cord-256444-grw5s2pf	906	18	Van	Van	NNP
cord-256444-grw5s2pf	906	19	Marle	Marle	NNP
cord-256444-grw5s2pf	906	20	et	et	NNP
cord-256444-grw5s2pf	906	21	al	al	NNP
cord-256444-grw5s2pf	906	22	.	.	NNP
cord-256444-grw5s2pf	906	23	,	,	,
cord-256444-grw5s2pf	906	24	1995	1995	CD
cord-256444-grw5s2pf	906	25	;	;	:
cord-256444-grw5s2pf	906	26	Krishnan	Krishnan	NNP
cord-256444-grw5s2pf	906	27	et	et	NNP
cord-256444-grw5s2pf	906	28	al	al	NNP
cord-256444-grw5s2pf	906	29	.	.	NNP
cord-256444-grw5s2pf	906	30	,	,	,
cord-256444-grw5s2pf	906	31	1996	1996	CD
cord-256444-grw5s2pf	906	32	)	)	-RRB-
cord-256444-grw5s2pf	906	33	.	.	.
cord-256444-grw5s2pf	907	1	The	the	DT
cord-256444-grw5s2pf	907	2	sequences	sequence	NNS
cord-256444-grw5s2pf	907	3	near	near	IN
cord-256444-grw5s2pf	907	4	the	the	DT
cord-256444-grw5s2pf	907	5	IGs	ig	NNS
cord-256444-grw5s2pf	907	6	may	may	MD
cord-256444-grw5s2pf	907	7	suppress	suppress	VB
cord-256444-grw5s2pf	907	8	transcription	transcription	NN
cord-256444-grw5s2pf	907	9	(	(	-LRB-
cord-256444-grw5s2pf	907	10	Jeong	Jeong	NNP
cord-256444-grw5s2pf	907	11	et	et	NNP
cord-256444-grw5s2pf	907	12	al	al	NNP
cord-256444-grw5s2pf	907	13	.	.	NNP
cord-256444-grw5s2pf	907	14	,	,	,
cord-256444-grw5s2pf	907	15	1996	1996	CD
cord-256444-grw5s2pf	907	16	)	)	-RRB-
cord-256444-grw5s2pf	907	17	.	.	.
cord-256444-grw5s2pf	908	1	b.	b.	NNP
cord-256444-grw5s2pf	909	1	The	the	DT
cord-256444-grw5s2pf	909	2	Leader	Leader	NNP
cord-256444-grw5s2pf	909	3	Sequence	sequence	NN
cord-256444-grw5s2pf	909	4	at	at	IN
cord-256444-grw5s2pf	909	5	the	the	DT
cord-256444-grw5s2pf	909	6	5	5	CD
cord-256444-grw5s2pf	909	7	'	'	''
cord-256444-grw5s2pf	909	8	End	end	NN
cord-256444-grw5s2pf	909	9	of	of	IN
cord-256444-grw5s2pf	909	10	the	the	DT
cord-256444-grw5s2pf	909	11	DZ	DZ	NNP
cord-256444-grw5s2pf	909	12	RNA	RNA	NNP
cord-256444-grw5s2pf	909	13	.	.	.
cord-256444-grw5s2pf	910	1	The	the	DT
cord-256444-grw5s2pf	910	2	leader	leader	NN
cord-256444-grw5s2pf	910	3	sequence	sequence	NN
cord-256444-grw5s2pf	910	4	at	at	IN
cord-256444-grw5s2pf	910	5	the	the	DT
cord-256444-grw5s2pf	910	6	5	5	CD
cord-256444-grw5s2pf	910	7	'	'	NN
cord-256444-grw5s2pf	910	8	end	end	NN
cord-256444-grw5s2pf	910	9	of	of	IN
cord-256444-grw5s2pf	910	10	the	the	DT
cord-256444-grw5s2pf	910	11	viral	viral	JJ
cord-256444-grw5s2pf	910	12	genomic	genomic	JJ
cord-256444-grw5s2pf	910	13	RNA	RNA	NNP
cord-256444-grw5s2pf	910	14	becomes	become	VBZ
cord-256444-grw5s2pf	910	15	the	the	DT
cord-256444-grw5s2pf	910	16	leader	leader	NN
cord-256444-grw5s2pf	910	17	sequence	sequence	NN
cord-256444-grw5s2pf	910	18	of	of	IN
cord-256444-grw5s2pf	910	19	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	910	20	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	910	21	;	;	:
cord-256444-grw5s2pf	910	22	thus	thus	RB
cord-256444-grw5s2pf	910	23	,	,	,
cord-256444-grw5s2pf	910	24	it	-PRON-	PRP
cord-256444-grw5s2pf	910	25	fills	fill	VBZ
cord-256444-grw5s2pf	910	26	a	a	DT
cord-256444-grw5s2pf	910	27	structural	structural	JJ
cord-256444-grw5s2pf	910	28	role	role	NN
cord-256444-grw5s2pf	910	29	for	for	IN
cord-256444-grw5s2pf	910	30	mRNA	mRNA	NNP
cord-256444-grw5s2pf	910	31	synthesis	synthesis	NN
cord-256444-grw5s2pf	910	32	.	.	.
cord-256444-grw5s2pf	911	1	However	however	RB
cord-256444-grw5s2pf	911	2	,	,	,
cord-256444-grw5s2pf	911	3	the	the	DT
cord-256444-grw5s2pf	911	4	leader	leader	NN
cord-256444-grw5s2pf	911	5	RNA	RNA	NNP
cord-256444-grw5s2pf	911	6	of	of	IN
cord-256444-grw5s2pf	911	7	the	the	DT
cord-256444-grw5s2pf	911	8	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	911	9	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	911	10	is	be	VBZ
cord-256444-grw5s2pf	911	11	not	not	RB
cord-256444-grw5s2pf	911	12	derived	derive	VBN
cord-256444-grw5s2pf	911	13	exclusively	exclusively	RB
cord-256444-grw5s2pf	911	14	from	from	IN
cord-256444-grw5s2pf	911	15	the	the	DT
cord-256444-grw5s2pf	911	16	leader	leader	NN
cord-256444-grw5s2pf	911	17	RNA	RNA	NNP
cord-256444-grw5s2pf	911	18	of	of	IN
cord-256444-grw5s2pf	911	19	the	the	DT
cord-256444-grw5s2pf	911	20	same	same	JJ
cord-256444-grw5s2pf	911	21	(	(	-LRB-
cord-256444-grw5s2pf	911	22	DI	DI	NNP
cord-256444-grw5s2pf	911	23	)	)	-RRB-
cord-256444-grw5s2pf	911	24	RNA	RNA	NNP
cord-256444-grw5s2pf	911	25	;	;	:
cord-256444-grw5s2pf	911	26	in	in	IN
cord-256444-grw5s2pf	911	27	fact	fact	NN
cord-256444-grw5s2pf	911	28	,	,	,
cord-256444-grw5s2pf	911	29	most	most	JJS
cord-256444-grw5s2pf	911	30	are	be	VBP
cord-256444-grw5s2pf	911	31	derived	derive	VBN
cord-256444-grw5s2pf	911	32	in	in	IN
cord-256444-grw5s2pf	911	33	trans	trans	NNP
cord-256444-grw5s2pf	911	34	from	from	IN
cord-256444-grw5s2pf	911	35	a	a	DT
cord-256444-grw5s2pf	911	36	separate	separate	JJ
cord-256444-grw5s2pf	911	37	RNA	rna	NN
cord-256444-grw5s2pf	911	38	molecule	molecule	NN
cord-256444-grw5s2pf	911	39	,	,	,
cord-256444-grw5s2pf	911	40	such	such	JJ
cord-256444-grw5s2pf	911	41	as	as	IN
cord-256444-grw5s2pf	911	42	helper	helper	NN
cord-256444-grw5s2pf	911	43	virus	virus	NN
cord-256444-grw5s2pf	911	44	RNA	RNA	NNP
cord-256444-grw5s2pf	911	45	(	(	-LRB-
cord-256444-grw5s2pf	911	46	Jeong	Jeong	NNP
cord-256444-grw5s2pf	911	47	and	and	CC
cord-256444-grw5s2pf	911	48	Makino	Makino	NNP
cord-256444-grw5s2pf	911	49	,	,	,
cord-256444-grw5s2pf	911	50	1994	1994	CD
cord-256444-grw5s2pf	911	51	;	;	:
cord-256444-grw5s2pf	911	52	Liao	Liao	NNP
cord-256444-grw5s2pf	911	53	and	and	CC
cord-256444-grw5s2pf	911	54	Lai	Lai	NNP
cord-256444-grw5s2pf	911	55	,	,	,
cord-256444-grw5s2pf	911	56	1994	1994	CD
cord-256444-grw5s2pf	911	57	;	;	:
cord-256444-grw5s2pf	911	58	Zhang	Zhang	NNP
cord-256444-grw5s2pf	911	59	et	et	NNP
cord-256444-grw5s2pf	911	60	al	al	NNP
cord-256444-grw5s2pf	911	61	.	.	NNP
cord-256444-grw5s2pf	911	62	,	,	,
cord-256444-grw5s2pf	911	63	199413	199413	CD
cord-256444-grw5s2pf	911	64	)	)	-RRB-
cord-256444-grw5s2pf	911	65	.	.	.
cord-256444-grw5s2pf	912	1	Nevertheless	nevertheless	RB
cord-256444-grw5s2pf	912	2	,	,	,
cord-256444-grw5s2pf	912	3	mRNA	mrna	NN
cord-256444-grw5s2pf	912	4	transcription	transcription	NN
cord-256444-grw5s2pf	912	5	from	from	IN
cord-256444-grw5s2pf	912	6	an	an	DT
cord-256444-grw5s2pf	912	7	IG	IG	NNP
cord-256444-grw5s2pf	912	8	site	site	NN
cord-256444-grw5s2pf	912	9	in	in	IN
cord-256444-grw5s2pf	912	10	the	the	DT
cord-256444-grw5s2pf	912	11	DI	DI	NNP
cord-256444-grw5s2pf	912	12	RNA	RNA	NNP
cord-256444-grw5s2pf	912	13	still	still	RB
cord-256444-grw5s2pf	912	14	requires	require	VBZ
cord-256444-grw5s2pf	912	15	the	the	DT
cord-256444-grw5s2pf	912	16	presence	presence	NN
cord-256444-grw5s2pf	912	17	of	of	IN
cord-256444-grw5s2pf	912	18	a	a	DT
cord-256444-grw5s2pf	912	19	leader	leader	NN
cord-256444-grw5s2pf	912	20	RNA	RNA	NNP
cord-256444-grw5s2pf	912	21	sequence	sequence	NN
cord-256444-grw5s2pf	912	22	at	at	IN
cord-256444-grw5s2pf	912	23	the	the	DT
cord-256444-grw5s2pf	912	24	5	5	CD
cord-256444-grw5s2pf	912	25	'	'	NN
cord-256444-grw5s2pf	912	26	end	end	NN
cord-256444-grw5s2pf	912	27	of	of	IN
cord-256444-grw5s2pf	912	28	the	the	DT
cord-256444-grw5s2pf	912	29	DI	DI	NNP
cord-256444-grw5s2pf	912	30	RNA	RNA	NNP
cord-256444-grw5s2pf	912	31	as	as	IN
cord-256444-grw5s2pf	912	32	a	a	DT
cord-256444-grw5s2pf	912	33	cis	cis	NN
cord-256444-grw5s2pf	912	34	-	-	HYPH
cord-256444-grw5s2pf	912	35	acting	acting	JJ
cord-256444-grw5s2pf	912	36	sequence	sequence	NN
cord-256444-grw5s2pf	912	37	.	.	.
cord-256444-grw5s2pf	913	1	Deletion	deletion	NN
cord-256444-grw5s2pf	913	2	of	of	IN
cord-256444-grw5s2pf	913	3	this	this	DT
cord-256444-grw5s2pf	913	4	cis	cis	NNP
cord-256444-grw5s2pf	913	5	-	-	HYPH
cord-256444-grw5s2pf	913	6	acting	act	VBG
cord-256444-grw5s2pf	913	7	leader	leader	NN
cord-256444-grw5s2pf	913	8	abolished	abolish	VBD
cord-256444-grw5s2pf	913	9	transcription	transcription	NN
cord-256444-grw5s2pf	913	10	.	.	.
cord-256444-grw5s2pf	914	1	Furthermore	furthermore	RB
cord-256444-grw5s2pf	914	2	,	,	,
cord-256444-grw5s2pf	914	3	the	the	DT
cord-256444-grw5s2pf	914	4	sequence	sequence	NN
cord-256444-grw5s2pf	914	5	of	of	IN
cord-256444-grw5s2pf	914	6	this	this	DT
cord-256444-grw5s2pf	914	7	leader	leader	NN
cord-256444-grw5s2pf	914	8	RNA	RNA	NNP
cord-256444-grw5s2pf	914	9	,	,	,
cord-256444-grw5s2pf	914	10	particularly	particularly	RB
cord-256444-grw5s2pf	914	11	its	-PRON-	PRP$
cord-256444-grw5s2pf	914	12	3	3	CD
cord-256444-grw5s2pf	914	13	'	'	NN
cord-256444-grw5s2pf	914	14	end	end	NN
cord-256444-grw5s2pf	914	15	sequence	sequence	NN
cord-256444-grw5s2pf	914	16	,	,	,
cord-256444-grw5s2pf	914	17	can	can	MD
cord-256444-grw5s2pf	914	18	affect	affect	VB
cord-256444-grw5s2pf	914	19	the	the	DT
cord-256444-grw5s2pf	914	20	efficiency	efficiency	NN
cord-256444-grw5s2pf	914	21	of	of	IN
cord-256444-grw5s2pf	914	22	transcription	transcription	NN
cord-256444-grw5s2pf	914	23	from	from	IN
cord-256444-grw5s2pf	914	24	certain	certain	JJ
cord-256444-grw5s2pf	914	25	IG	IG	NNP
cord-256444-grw5s2pf	914	26	sequences	sequence	NNS
cord-256444-grw5s2pf	914	27	on	on	IN
cord-256444-grw5s2pf	914	28	the	the	DT
cord-256444-grw5s2pf	914	29	DI	DI	NNP
cord-256444-grw5s2pf	914	30	RNA	RNA	NNP
cord-256444-grw5s2pf	914	31	(	(	-LRB-
cord-256444-grw5s2pf	914	32	Zhang	Zhang	NNP
cord-256444-grw5s2pf	914	33	et	et	NNP
cord-256444-grw5s2pf	914	34	al	al	NNP
cord-256444-grw5s2pf	914	35	.	.	NNP
cord-256444-grw5s2pf	914	36	,	,	,
cord-256444-grw5s2pf	914	37	199413	199413	CD
cord-256444-grw5s2pf	914	38	)	)	-RRB-
cord-256444-grw5s2pf	914	39	.	.	.
cord-256444-grw5s2pf	915	1	For	for	IN
cord-256444-grw5s2pf	915	2	example	example	NN
cord-256444-grw5s2pf	915	3	,	,	,
cord-256444-grw5s2pf	915	4	the	the	DT
cord-256444-grw5s2pf	915	5	leader	leader	NN
cord-256444-grw5s2pf	915	6	RNA	RNA	NNP
cord-256444-grw5s2pf	915	7	containing	contain	VBG
cord-256444-grw5s2pf	915	8	two	two	CD
cord-256444-grw5s2pf	915	9	pentanucleotide	pentanucleotide	NN
cord-256444-grw5s2pf	915	10	(	(	-LRB-
cord-256444-grw5s2pf	915	11	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	915	12	)	)	-RRB-
cord-256444-grw5s2pf	915	13	repeats	repeat	VBZ
cord-256444-grw5s2pf	915	14	transcribes	transcribe	VBZ
cord-256444-grw5s2pf	915	15	an	an	DT
cord-256444-grw5s2pf	915	16	mRNA	mrna	NN
cord-256444-grw5s2pf	915	17	from	from	IN
cord-256444-grw5s2pf	915	18	the	the	DT
cord-256444-grw5s2pf	915	19	IG	IG	NNP
cord-256444-grw5s2pf	915	20	2	2	CD
cord-256444-grw5s2pf	915	21	-	-	SYM
cord-256444-grw5s2pf	915	22	1	1	CD
cord-256444-grw5s2pf	915	23	site	site	NN
cord-256444-grw5s2pf	915	24	more	more	RBR
cord-256444-grw5s2pf	915	25	efficiently	efficiently	RB
cord-256444-grw5s2pf	915	26	than	than	IN
cord-256444-grw5s2pf	915	27	the	the	DT
cord-256444-grw5s2pf	915	28	leader	leader	NN
cord-256444-grw5s2pf	915	29	RNA	RNA	NNP
cord-256444-grw5s2pf	915	30	with	with	IN
cord-256444-grw5s2pf	915	31	three	three	CD
cord-256444-grw5s2pf	915	32	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	915	33	repeats	repeat	VBZ
cord-256444-grw5s2pf	915	34	.	.	.
cord-256444-grw5s2pf	916	1	Thus	thus	RB
cord-256444-grw5s2pf	916	2	,	,	,
cord-256444-grw5s2pf	916	3	the	the	DT
cord-256444-grw5s2pf	916	4	cis	cis	NNP
cord-256444-grw5s2pf	916	5	-	-	HYPH
cord-256444-grw5s2pf	916	6	acting	act	VBG
cord-256444-grw5s2pf	916	7	leader	leader	NN
cord-256444-grw5s2pf	916	8	RNA	RNA	NNP
cord-256444-grw5s2pf	916	9	plays	play	VBZ
cord-256444-grw5s2pf	916	10	a	a	DT
cord-256444-grw5s2pf	916	11	role	role	NN
cord-256444-grw5s2pf	916	12	similar	similar	JJ
cord-256444-grw5s2pf	916	13	to	to	IN
cord-256444-grw5s2pf	916	14	that	that	DT
cord-256444-grw5s2pf	916	15	of	of	IN
cord-256444-grw5s2pf	916	16	an	an	DT
cord-256444-grw5s2pf	916	17	enhancer	enhancer	NN
cord-256444-grw5s2pf	916	18	.	.	.
cord-256444-grw5s2pf	917	1	These	these	DT
cord-256444-grw5s2pf	917	2	findings	finding	NNS
cord-256444-grw5s2pf	917	3	suggest	suggest	VBP
cord-256444-grw5s2pf	917	4	that	that	IN
cord-256444-grw5s2pf	917	5	the	the	DT
cord-256444-grw5s2pf	917	6	leader	leader	NN
cord-256444-grw5s2pf	917	7	RNA	RNA	NNP
cord-256444-grw5s2pf	917	8	serves	serve	VBZ
cord-256444-grw5s2pf	917	9	two	two	CD
cord-256444-grw5s2pf	917	10	functions	function	NNS
cord-256444-grw5s2pf	917	11	:	:	:
cord-256444-grw5s2pf	917	12	(	(	-LRB-
cord-256444-grw5s2pf	917	13	1	1	LS
cord-256444-grw5s2pf	917	14	)	)	-RRB-
cord-256444-grw5s2pf	917	15	it	-PRON-	PRP
cord-256444-grw5s2pf	917	16	supplies	supply	VBZ
cord-256444-grw5s2pf	917	17	the	the	DT
cord-256444-grw5s2pf	917	18	leader	leader	NN
cord-256444-grw5s2pf	917	19	RNA	RNA	NNP
cord-256444-grw5s2pf	917	20	to	to	IN
cord-256444-grw5s2pf	917	21	the	the	DT
cord-256444-grw5s2pf	917	22	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	917	23	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	917	24	,	,	,
cord-256444-grw5s2pf	917	25	and	and	CC
cord-256444-grw5s2pf	917	26	(	(	-LRB-
cord-256444-grw5s2pf	917	27	2	2	LS
cord-256444-grw5s2pf	917	28	)	)	-RRB-
cord-256444-grw5s2pf	917	29	it	-PRON-	PRP
cord-256444-grw5s2pf	917	30	serves	serve	VBZ
cord-256444-grw5s2pf	917	31	as	as	IN
cord-256444-grw5s2pf	917	32	an	an	DT
cord-256444-grw5s2pf	917	33	enhancer	enhancer	NN
cord-256444-grw5s2pf	917	34	-	-	HYPH
cord-256444-grw5s2pf	917	35	like	like	JJ
cord-256444-grw5s2pf	917	36	sequence	sequence	NN
cord-256444-grw5s2pf	917	37	to	to	TO
cord-256444-grw5s2pf	917	38	regulate	regulate	VB
cord-256444-grw5s2pf	917	39	transcription	transcription	NN
cord-256444-grw5s2pf	917	40	.	.	.
cord-256444-grw5s2pf	918	1	This	this	DT
cord-256444-grw5s2pf	918	2	finding	finding	NN
cord-256444-grw5s2pf	918	3	also	also	RB
cord-256444-grw5s2pf	918	4	suggests	suggest	VBZ
cord-256444-grw5s2pf	918	5	that	that	IN
cord-256444-grw5s2pf	918	6	there	there	EX
cord-256444-grw5s2pf	918	7	is	be	VBZ
cord-256444-grw5s2pf	918	8	either	either	CC
cord-256444-grw5s2pf	918	9	a	a	DT
cord-256444-grw5s2pf	918	10	direct	direct	JJ
cord-256444-grw5s2pf	918	11	or	or	CC
cord-256444-grw5s2pf	918	12	an	an	DT
cord-256444-grw5s2pf	918	13	indirect	indirect	JJ
cord-256444-grw5s2pf	918	14	interaction	interaction	NN
cord-256444-grw5s2pf	918	15	between	between	IN
cord-256444-grw5s2pf	918	16	the	the	DT
cord-256444-grw5s2pf	918	17	leader	leader	NN
cord-256444-grw5s2pf	918	18	and	and	CC
cord-256444-grw5s2pf	918	19	IG	IG	NNP
cord-256444-grw5s2pf	918	20	sequences	sequence	NNS
cord-256444-grw5s2pf	918	21	.	.	.
cord-256444-grw5s2pf	919	1	Some	some	DT
cord-256444-grw5s2pf	919	2	additional	additional	JJ
cord-256444-grw5s2pf	919	3	sequences	sequence	NNS
cord-256444-grw5s2pf	919	4	downstream	downstream	RB
cord-256444-grw5s2pf	919	5	of	of	IN
cord-256444-grw5s2pf	919	6	the	the	DT
cord-256444-grw5s2pf	919	7	leader	leader	NN
cord-256444-grw5s2pf	919	8	may	may	MD
cord-256444-grw5s2pf	919	9	also	also	RB
cord-256444-grw5s2pf	919	10	enhance	enhance	VB
cord-256444-grw5s2pf	919	11	transcription	transcription	NN
cord-256444-grw5s2pf	919	12	from	from	IN
cord-256444-grw5s2pf	919	13	an	an	DT
cord-256444-grw5s2pf	919	14	IG	IG	NNP
cord-256444-grw5s2pf	919	15	site	site	NN
cord-256444-grw5s2pf	919	16	in	in	IN
cord-256444-grw5s2pf	919	17	the	the	DT
cord-256444-grw5s2pf	919	18	DI	DI	NNP
cord-256444-grw5s2pf	919	19	RNA	RNA	NNP
cord-256444-grw5s2pf	919	20	;	;	:
cord-256444-grw5s2pf	919	21	however	however	RB
cord-256444-grw5s2pf	919	22	,	,	,
cord-256444-grw5s2pf	919	23	the	the	DT
cord-256444-grw5s2pf	919	24	precise	precise	JJ
cord-256444-grw5s2pf	919	25	sequence	sequence	NN
cord-256444-grw5s2pf	919	26	requirement	requirement	NN
cord-256444-grw5s2pf	919	27	is	be	VBZ
cord-256444-grw5s2pf	919	28	not	not	RB
cord-256444-grw5s2pf	919	29	known	know	VBN
cord-256444-grw5s2pf	919	30	.	.	.
cord-256444-grw5s2pf	920	1	This	this	DT
cord-256444-grw5s2pf	920	2	sequence	sequence	NN
cord-256444-grw5s2pf	920	3	requirement	requirement	NN
cord-256444-grw5s2pf	920	4	shows	show	VBZ
cord-256444-grw5s2pf	920	5	some	some	DT
cord-256444-grw5s2pf	920	6	virus	virus	NN
cord-256444-grw5s2pf	920	7	sequence	sequence	NN
cord-256444-grw5s2pf	920	8	specificity	specificity	NN
cord-256444-grw5s2pf	920	9	,	,	,
cord-256444-grw5s2pf	920	10	since	since	IN
cord-256444-grw5s2pf	920	11	it	-PRON-	PRP
cord-256444-grw5s2pf	920	12	can	can	MD
cord-256444-grw5s2pf	920	13	not	not	RB
cord-256444-grw5s2pf	920	14	be	be	VB
cord-256444-grw5s2pf	920	15	replaced	replace	VBN
cord-256444-grw5s2pf	920	16	with	with	IN
cord-256444-grw5s2pf	920	17	other	other	JJ
cord-256444-grw5s2pf	920	18	viral	viral	JJ
cord-256444-grw5s2pf	920	19	RNA	RNA	NNP
cord-256444-grw5s2pf	920	20	sequences	sequence	NNS
cord-256444-grw5s2pf	920	21	.	.	.
cord-256444-grw5s2pf	921	1	It	-PRON-	PRP
cord-256444-grw5s2pf	921	2	may	may	MD
cord-256444-grw5s2pf	921	3	be	be	VB
cord-256444-grw5s2pf	921	4	needed	need	VBN
cord-256444-grw5s2pf	921	5	to	to	TO
cord-256444-grw5s2pf	921	6	maintain	maintain	VB
cord-256444-grw5s2pf	921	7	overall	overall	JJ
cord-256444-grw5s2pf	921	8	RNA	RNA	NNP
cord-256444-grw5s2pf	921	9	conformation	conformation	NN
cord-256444-grw5s2pf	921	10	for	for	IN
cord-256444-grw5s2pf	921	11	the	the	DT
cord-256444-grw5s2pf	921	12	recognition	recognition	NN
cord-256444-grw5s2pf	921	13	of	of	IN
cord-256444-grw5s2pf	921	14	the	the	DT
cord-256444-grw5s2pf	921	15	IG	IG	NNP
cord-256444-grw5s2pf	921	16	sequence	sequence	NN
cord-256444-grw5s2pf	921	17	.	.	.
cord-256444-grw5s2pf	922	1	c.	c.	NNP
cord-256444-grw5s2pf	923	1	The	the	DT
cord-256444-grw5s2pf	923	2	3	3	CD
cord-256444-grw5s2pf	923	3	'	'	POS
cord-256444-grw5s2pf	923	4	UTR	UTR	NNP
cord-256444-grw5s2pf	923	5	.	.	.
cord-256444-grw5s2pf	924	1	In	in	IN
cord-256444-grw5s2pf	924	2	an	an	DT
cord-256444-grw5s2pf	924	3	MHV	MHV	NNP
cord-256444-grw5s2pf	924	4	DI	DI	NNP
cord-256444-grw5s2pf	924	5	RNA	RNA	NNP
cord-256444-grw5s2pf	924	6	construct	construct	NN
cord-256444-grw5s2pf	924	7	,	,	,
cord-256444-grw5s2pf	924	8	partial	partial	JJ
cord-256444-grw5s2pf	924	9	deletion	deletion	NN
cord-256444-grw5s2pf	924	10	of	of	IN
cord-256444-grw5s2pf	924	11	the	the	DT
cord-256444-grw5s2pf	924	12	3	3	CD
cord-256444-grw5s2pf	924	13	'	'	POS
cord-256444-grw5s2pf	924	14	UTR	UTR	NNP
cord-256444-grw5s2pf	924	15	completely	completely	RB
cord-256444-grw5s2pf	924	16	abolished	abolish	VBD
cord-256444-grw5s2pf	924	17	transcription	transcription	NN
cord-256444-grw5s2pf	924	18	from	from	IN
cord-256444-grw5s2pf	924	19	an	an	DT
cord-256444-grw5s2pf	924	20	upstream	upstream	JJ
cord-256444-grw5s2pf	924	21	IG	ig	NN
cord-256444-grw5s2pf	924	22	site	site	NN
cord-256444-grw5s2pf	924	23	in	in	IN
cord-256444-grw5s2pf	924	24	the	the	DT
cord-256444-grw5s2pf	924	25	DI	DI	NNP
cord-256444-grw5s2pf	924	26	RNA	RNA	NNP
cord-256444-grw5s2pf	925	1	(	(	-LRB-
cord-256444-grw5s2pf	925	2	Lin	Lin	NNP
cord-256444-grw5s2pf	925	3	et	et	NNP
cord-256444-grw5s2pf	925	4	al	al	NNP
cord-256444-grw5s2pf	925	5	.	.	NNP
cord-256444-grw5s2pf	925	6	,	,	,
cord-256444-grw5s2pf	925	7	1996	1996	CD
cord-256444-grw5s2pf	925	8	)	)	-RRB-
cord-256444-grw5s2pf	925	9	.	.	.
cord-256444-grw5s2pf	926	1	This	this	DT
cord-256444-grw5s2pf	926	2	stretch	stretch	NN
cord-256444-grw5s2pf	926	3	of	of	IN
cord-256444-grw5s2pf	926	4	3	3	CD
cord-256444-grw5s2pf	926	5	'	'	POS
cord-256444-grw5s2pf	926	6	UTR	UTR	NNP
cord-256444-grw5s2pf	926	7	is	be	VBZ
cord-256444-grw5s2pf	926	8	probably	probably	RB
cord-256444-grw5s2pf	926	9	involved	involve	VBN
cord-256444-grw5s2pf	926	10	in	in	IN
cord-256444-grw5s2pf	926	11	positive	positive	JJ
cord-256444-grw5s2pf	926	12	-	-	HYPH
cord-256444-grw5s2pf	926	13	strand	strand	NN
cord-256444-grw5s2pf	926	14	RNA	RNA	NNP
cord-256444-grw5s2pf	926	15	synthesis	synthesis	NN
cord-256444-grw5s2pf	926	16	,	,	,
cord-256444-grw5s2pf	926	17	since	since	IN
cord-256444-grw5s2pf	926	18	the	the	DT
cord-256444-grw5s2pf	926	19	length	length	NN
cord-256444-grw5s2pf	926	20	of	of	IN
cord-256444-grw5s2pf	926	21	this	this	DT
cord-256444-grw5s2pf	926	22	required	require	VBN
cord-256444-grw5s2pf	926	23	sequence	sequence	NN
cord-256444-grw5s2pf	926	24	(	(	-LRB-
cord-256444-grw5s2pf	926	25	305	305	CD
cord-256444-grw5s2pf	926	26	nt	nt	NN
cord-256444-grw5s2pf	926	27	)	)	-RRB-
cord-256444-grw5s2pf	926	28	is	be	VBZ
cord-256444-grw5s2pf	926	29	significantly	significantly	RB
cord-256444-grw5s2pf	926	30	longer	long	JJR
cord-256444-grw5s2pf	926	31	than	than	IN
cord-256444-grw5s2pf	926	32	that	that	DT
cord-256444-grw5s2pf	926	33	required	require	VBN
cord-256444-grw5s2pf	926	34	for	for	IN
cord-256444-grw5s2pf	926	35	negative	negative	JJ
cord-256444-grw5s2pf	926	36	-	-	HYPH
cord-256444-grw5s2pf	926	37	strand	strand	NN
cord-256444-grw5s2pf	926	38	RNA	RNA	NNP
cord-256444-grw5s2pf	926	39	synthesis	synthesis	NN
cord-256444-grw5s2pf	926	40	(	(	-LRB-
cord-256444-grw5s2pf	926	41	55	55	CD
cord-256444-grw5s2pf	926	42	nt	nt	NN
cord-256444-grw5s2pf	926	43	)	)	-RRB-
cord-256444-grw5s2pf	926	44	.	.	.
cord-256444-grw5s2pf	927	1	The	the	DT
cord-256444-grw5s2pf	927	2	3	3	CD
cord-256444-grw5s2pf	927	3	'	'	POS
cord-256444-grw5s2pf	927	4	UTR	UTR	NNP
cord-256444-grw5s2pf	927	5	requirement	requirement	NN
cord-256444-grw5s2pf	927	6	for	for	IN
cord-256444-grw5s2pf	927	7	mRNA	mRNA	NNP
cord-256444-grw5s2pf	927	8	transcription	transcription	NN
cord-256444-grw5s2pf	927	9	is	be	VBZ
cord-256444-grw5s2pf	927	10	surprising	surprising	JJ
cord-256444-grw5s2pf	927	11	,	,	,
cord-256444-grw5s2pf	927	12	since	since	IN
cord-256444-grw5s2pf	927	13	positive	positive	JJ
cord-256444-grw5s2pf	927	14	-	-	HYPH
cord-256444-grw5s2pf	927	15	strand	strand	NN
cord-256444-grw5s2pf	927	16	RNA	RNA	NNP
cord-256444-grw5s2pf	927	17	synthesis	synthesis	NN
cord-256444-grw5s2pf	927	18	starts	start	VBZ
cord-256444-grw5s2pf	927	19	from	from	IN
cord-256444-grw5s2pf	927	20	the	the	DT
cord-256444-grw5s2pf	927	21	5	5	CD
cord-256444-grw5s2pf	927	22	'	'	NN
cord-256444-grw5s2pf	927	23	end	end	NN
cord-256444-grw5s2pf	927	24	;	;	:
cord-256444-grw5s2pf	927	25	thus	thus	RB
cord-256444-grw5s2pf	927	26	,	,	,
cord-256444-grw5s2pf	927	27	the	the	DT
cord-256444-grw5s2pf	927	28	3	3	CD
cord-256444-grw5s2pf	927	29	'	'	NN
cord-256444-grw5s2pf	927	30	end	end	NN
cord-256444-grw5s2pf	927	31	sequence	sequence	NN
cord-256444-grw5s2pf	927	32	is	be	VBZ
cord-256444-grw5s2pf	927	33	the	the	DT
cord-256444-grw5s2pf	927	34	last	last	JJ
cord-256444-grw5s2pf	927	35	to	to	TO
cord-256444-grw5s2pf	927	36	be	be	VB
cord-256444-grw5s2pf	927	37	transcribed	transcribe	VBN
cord-256444-grw5s2pf	927	38	.	.	.
cord-256444-grw5s2pf	928	1	This	this	DT
cord-256444-grw5s2pf	928	2	3	3	CD
cord-256444-grw5s2pf	928	3	'	'	POS
cord-256444-grw5s2pf	928	4	UTR	UTR	NNP
cord-256444-grw5s2pf	928	5	sequence	sequence	NN
cord-256444-grw5s2pf	928	6	requirement	requirement	NN
cord-256444-grw5s2pf	928	7	is	be	VBZ
cord-256444-grw5s2pf	928	8	similar	similar	JJ
cord-256444-grw5s2pf	928	9	to	to	IN
cord-256444-grw5s2pf	928	10	that	that	DT
cord-256444-grw5s2pf	928	11	for	for	IN
cord-256444-grw5s2pf	928	12	RNA	RNA	NNP
cord-256444-grw5s2pf	928	13	replication	replication	NN
cord-256444-grw5s2pf	928	14	(	(	-LRB-
cord-256444-grw5s2pf	929	1	Kim	Kim	NNP
cord-256444-grw5s2pf	929	2	et	et	NNP
cord-256444-grw5s2pf	929	3	al	al	NNP
cord-256444-grw5s2pf	929	4	.	.	NNP
cord-256444-grw5s2pf	929	5	,	,	,
cord-256444-grw5s2pf	929	6	1993b	1993b	CD
cord-256444-grw5s2pf	929	7	;	;	:
cord-256444-grw5s2pf	929	8	Lin	Lin	NNP
cord-256444-grw5s2pf	929	9	and	and	CC
cord-256444-grw5s2pf	929	10	Lai	Lai	NNP
cord-256444-grw5s2pf	929	11	,	,	,
cord-256444-grw5s2pf	929	12	1993	1993	CD
cord-256444-grw5s2pf	929	13	)	)	-RRB-
cord-256444-grw5s2pf	929	14	(	(	-LRB-
cord-256444-grw5s2pf	929	15	see	see	VB
cord-256444-grw5s2pf	929	16	Section	section	NN
cord-256444-grw5s2pf	929	17	V	v	NN
cord-256444-grw5s2pf	929	18	,	,	,
cord-256444-grw5s2pf	929	19	F	F	NNP
cord-256444-grw5s2pf	929	20	)	)	-RRB-
cord-256444-grw5s2pf	929	21	.	.	.
cord-256444-grw5s2pf	930	1	This	this	DT
cord-256444-grw5s2pf	930	2	finding	finding	NN
cord-256444-grw5s2pf	930	3	suggests	suggest	VBZ
cord-256444-grw5s2pf	930	4	that	that	IN
cord-256444-grw5s2pf	930	5	the	the	DT
cord-256444-grw5s2pf	930	6	3	3	CD
cord-256444-grw5s2pf	930	7	'	'	NN
cord-256444-grw5s2pf	930	8	end	end	NN
cord-256444-grw5s2pf	930	9	may	may	MD
cord-256444-grw5s2pf	930	10	interact	interact	VB
cord-256444-grw5s2pf	930	11	with	with	IN
cord-256444-grw5s2pf	930	12	the	the	DT
cord-256444-grw5s2pf	930	13	5	5	CD
cord-256444-grw5s2pf	930	14	'	'	NN
cord-256444-grw5s2pf	930	15	end	end	NN
cord-256444-grw5s2pf	930	16	and	and	CC
cord-256444-grw5s2pf	930	17	possibly	possibly	RB
cord-256444-grw5s2pf	930	18	with	with	IN
cord-256444-grw5s2pf	930	19	IG	IG	NNP
cord-256444-grw5s2pf	930	20	sequences	sequence	NNS
cord-256444-grw5s2pf	930	21	during	during	IN
cord-256444-grw5s2pf	930	22	transcription	transcription	NN
cord-256444-grw5s2pf	930	23	.	.	.
cord-256444-grw5s2pf	931	1	A	a	DT
cord-256444-grw5s2pf	931	2	Nine	Nine	NNP
cord-256444-grw5s2pf	931	3	-	-	HYPH
cord-256444-grw5s2pf	931	4	Nucleotide	nucleotide	JJ
cord-256444-grw5s2pf	931	5	Sequence	sequence	NN
cord-256444-grw5s2pf	931	6	,	,	,
cord-256444-grw5s2pf	931	7	UUUAUAAAC	UUUAUAAAC	NNP
cord-256444-grw5s2pf	931	8	.	.	.
cord-256444-grw5s2pf	932	1	This	this	DT
cord-256444-grw5s2pf	932	2	sequence	sequence	NN
cord-256444-grw5s2pf	932	3	,	,	,
cord-256444-grw5s2pf	932	4	located	locate	VBN
cord-256444-grw5s2pf	932	5	immediately	immediately	RB
cord-256444-grw5s2pf	932	6	downstream	downstream	RB
cord-256444-grw5s2pf	932	7	from	from	IN
cord-256444-grw5s2pf	932	8	the	the	DT
cord-256444-grw5s2pf	932	9	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	932	10	repeats	repeat	VBZ
cord-256444-grw5s2pf	932	11	at	at	IN
cord-256444-grw5s2pf	932	12	the	the	DT
cord-256444-grw5s2pf	932	13	3	3	CD
cord-256444-grw5s2pf	932	14	'	'	NN
cord-256444-grw5s2pf	932	15	end	end	NN
cord-256444-grw5s2pf	932	16	of	of	IN
cord-256444-grw5s2pf	932	17	the	the	DT
cord-256444-grw5s2pf	932	18	leader	leader	NN
cord-256444-grw5s2pf	932	19	RNA	RNA	NNP
cord-256444-grw5s2pf	932	20	in	in	IN
cord-256444-grw5s2pf	932	21	the	the	DT
cord-256444-grw5s2pf	932	22	viral	viral	JJ
cord-256444-grw5s2pf	932	23	genome	genome	NN
cord-256444-grw5s2pf	932	24	,	,	,
cord-256444-grw5s2pf	932	25	plays	play	VBZ
cord-256444-grw5s2pf	932	26	a	a	DT
cord-256444-grw5s2pf	932	27	significant	significant	JJ
cord-256444-grw5s2pf	932	28	role	role	NN
cord-256444-grw5s2pf	932	29	in	in	IN
cord-256444-grw5s2pf	932	30	RNA	RNA	NNP
cord-256444-grw5s2pf	932	31	transcription	transcription	NN
cord-256444-grw5s2pf	932	32	.	.	.
cord-256444-grw5s2pf	933	1	It	-PRON-	PRP
cord-256444-grw5s2pf	933	2	is	be	VBZ
cord-256444-grw5s2pf	933	3	deleted	delete	VBN
cord-256444-grw5s2pf	933	4	from	from	IN
cord-256444-grw5s2pf	933	5	the	the	DT
cord-256444-grw5s2pf	933	6	genome	genome	NN
cord-256444-grw5s2pf	933	7	of	of	IN
cord-256444-grw5s2pf	933	8	one	one	CD
cord-256444-grw5s2pf	933	9	of	of	IN
cord-256444-grw5s2pf	933	10	the	the	DT
cord-256444-grw5s2pf	933	11	MHV	MHV	NNP
cord-256444-grw5s2pf	933	12	strains	strain	NNS
cord-256444-grw5s2pf	933	13	and	and	CC
cord-256444-grw5s2pf	933	14	is	be	VBZ
cord-256444-grw5s2pf	933	15	often	often	RB
cord-256444-grw5s2pf	933	16	deleted	delete	VBN
cord-256444-grw5s2pf	933	17	in	in	IN
cord-256444-grw5s2pf	933	18	naturally	naturally	RB
cord-256444-grw5s2pf	933	19	occurring	occur	VBG
cord-256444-grw5s2pf	933	20	DI	DI	NNP
cord-256444-grw5s2pf	933	21	RNAs	rna	NNS
cord-256444-grw5s2pf	933	22	.	.	.
cord-256444-grw5s2pf	934	1	In	in	IN
cord-256444-grw5s2pf	934	2	this	this	DT
cord-256444-grw5s2pf	934	3	particular	particular	JJ
cord-256444-grw5s2pf	934	4	MHV	MHV	NNP
cord-256444-grw5s2pf	934	5	strain	strain	NN
cord-256444-grw5s2pf	934	6	(	(	-LRB-
cord-256444-grw5s2pf	934	7	MHV-20	mhv-20	UH
cord-256444-grw5s2pf	934	8	,	,	,
cord-256444-grw5s2pf	934	9	the	the	DT
cord-256444-grw5s2pf	934	10	leader	leader	NN
cord-256444-grw5s2pf	934	11	-	-	HYPH
cord-256444-grw5s2pf	934	12	mRNA	mrna	NN
cord-256444-grw5s2pf	934	13	fusion	fusion	NN
cord-256444-grw5s2pf	934	14	sites	site	NNS
cord-256444-grw5s2pf	934	15	are	be	VBP
cord-256444-grw5s2pf	934	16	very	very	RB
cord-256444-grw5s2pf	934	17	heterogeneous	heterogeneous	JJ
cord-256444-grw5s2pf	934	18	and	and	CC
cord-256444-grw5s2pf	934	19	do	do	VBP
cord-256444-grw5s2pf	934	20	not	not	RB
cord-256444-grw5s2pf	934	21	always	always	RB
cord-256444-grw5s2pf	934	22	occur	occur	VB
cord-256444-grw5s2pf	934	23	at	at	IN
cord-256444-grw5s2pf	934	24	the	the	DT
cord-256444-grw5s2pf	934	25	usual	usual	JJ
cord-256444-grw5s2pf	934	26	UCUAAAC	UCUAAAC	NNP
cord-256444-grw5s2pf	934	27	sites	site	NNS
cord-256444-grw5s2pf	934	28	(	(	-LRB-
cord-256444-grw5s2pf	934	29	Zhang	Zhang	NNP
cord-256444-grw5s2pf	934	30	et	et	NNP
cord-256444-grw5s2pf	934	31	al	al	NNP
cord-256444-grw5s2pf	934	32	.	.	NNP
cord-256444-grw5s2pf	934	33	,	,	,
cord-256444-grw5s2pf	934	34	199413	199413	CD
cord-256444-grw5s2pf	934	35	)	)	-RRB-
cord-256444-grw5s2pf	934	36	.	.	.
cord-256444-grw5s2pf	935	1	This	this	DT
cord-256444-grw5s2pf	935	2	nine	nine	CD
cord-256444-grw5s2pf	935	3	-	-	HYPH
cord-256444-grw5s2pf	935	4	nucleotide	nucleotide	JJ
cord-256444-grw5s2pf	935	5	sequence	sequence	NN
cord-256444-grw5s2pf	935	6	can	can	MD
cord-256444-grw5s2pf	935	7	serve	serve	VB
cord-256444-grw5s2pf	935	8	as	as	IN
cord-256444-grw5s2pf	935	9	an	an	DT
cord-256444-grw5s2pf	935	10	mRNA	mrna	NN
cord-256444-grw5s2pf	935	11	start	start	NN
cord-256444-grw5s2pf	935	12	signal	signal	NN
cord-256444-grw5s2pf	935	13	,	,	,
cord-256444-grw5s2pf	935	14	allowing	allow	VBG
cord-256444-grw5s2pf	935	15	transcription	transcription	NN
cord-256444-grw5s2pf	935	16	of	of	IN
cord-256444-grw5s2pf	935	17	an	an	DT
cord-256444-grw5s2pf	935	18	almost	almost	RB
cord-256444-grw5s2pf	935	19	genomic	genomic	JJ
cord-256444-grw5s2pf	935	20	-	-	HYPH
cord-256444-grw5s2pf	935	21	length	length	NN
cord-256444-grw5s2pf	935	22	mRNA	mrna	NN
cord-256444-grw5s2pf	935	23	.	.	.
cord-256444-grw5s2pf	936	1	In	in	IN
cord-256444-grw5s2pf	936	2	the	the	DT
cord-256444-grw5s2pf	936	3	DI	DI	NNP
cord-256444-grw5s2pf	936	4	RNAs	rna	NNS
cord-256444-grw5s2pf	936	5	,	,	,
cord-256444-grw5s2pf	936	6	the	the	DT
cord-256444-grw5s2pf	936	7	presence	presence	NN
cord-256444-grw5s2pf	936	8	or	or	CC
cord-256444-grw5s2pf	936	9	absence	absence	NN
cord-256444-grw5s2pf	936	10	of	of	IN
cord-256444-grw5s2pf	936	11	this	this	DT
cord-256444-grw5s2pf	936	12	nine	nine	CD
cord-256444-grw5s2pf	936	13	-	-	HYPH
cord-256444-grw5s2pf	936	14	nucleotide	nucleotide	JJ
cord-256444-grw5s2pf	936	15	sequence	sequence	NN
cord-256444-grw5s2pf	936	16	influences	influence	NNS
cord-256444-grw5s2pf	936	17	transcription	transcription	NN
cord-256444-grw5s2pf	936	18	efficiency	efficiency	NN
cord-256444-grw5s2pf	936	19	from	from	IN
cord-256444-grw5s2pf	936	20	the	the	DT
cord-256444-grw5s2pf	936	21	downstream	downstream	JJ
cord-256444-grw5s2pf	936	22	IG	ig	NN
cord-256444-grw5s2pf	936	23	site	site	NN
cord-256444-grw5s2pf	936	24	and	and	CC
cord-256444-grw5s2pf	936	25	,	,	,
cord-256444-grw5s2pf	936	26	most	most	RBS
cord-256444-grw5s2pf	936	27	importantly	importantly	RB
cord-256444-grw5s2pf	936	28	,	,	,
cord-256444-grw5s2pf	936	29	affects	affect	VBZ
cord-256444-grw5s2pf	936	30	the	the	DT
cord-256444-grw5s2pf	936	31	source	source	NN
cord-256444-grw5s2pf	936	32	of	of	IN
cord-256444-grw5s2pf	936	33	the	the	DT
cord-256444-grw5s2pf	936	34	leader	leader	NN
cord-256444-grw5s2pf	936	35	RNA	RNA	NNP
cord-256444-grw5s2pf	936	36	incorporated	incorporate	VBD
cord-256444-grw5s2pf	936	37	into	into	IN
cord-256444-grw5s2pf	936	38	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	936	39	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	937	1	(	(	-LRB-
cord-256444-grw5s2pf	937	2	Zhang	Zhang	NNP
cord-256444-grw5s2pf	937	3	et	et	NNP
cord-256444-grw5s2pf	937	4	al	al	NNP
cord-256444-grw5s2pf	937	5	.	.	NNP
cord-256444-grw5s2pf	937	6	,	,	,
cord-256444-grw5s2pf	937	7	1994b	1994b	CD
cord-256444-grw5s2pf	937	8	)	)	-RRB-
cord-256444-grw5s2pf	937	9	.	.	.
cord-256444-grw5s2pf	938	1	When	when	WRB
cord-256444-grw5s2pf	938	2	this	this	DT
cord-256444-grw5s2pf	938	3	nine	nine	CD
cord-256444-grw5s2pf	938	4	-	-	HYPH
cord-256444-grw5s2pf	938	5	nucleotide	nucleotide	JJ
cord-256444-grw5s2pf	938	6	sequence	sequence	NN
cord-256444-grw5s2pf	938	7	is	be	VBZ
cord-256444-grw5s2pf	938	8	present	present	JJ
cord-256444-grw5s2pf	938	9	,	,	,
cord-256444-grw5s2pf	938	10	the	the	DT
cord-256444-grw5s2pf	938	11	leader	leader	NN
cord-256444-grw5s2pf	938	12	sequence	sequence	NN
cord-256444-grw5s2pf	938	13	in	in	IN
cord-256444-grw5s2pf	938	14	the	the	DT
cord-256444-grw5s2pf	938	15	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	938	16	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	938	17	is	be	VBZ
cord-256444-grw5s2pf	938	18	contributed	contribute	VBN
cord-256444-grw5s2pf	938	19	both	both	CC
cord-256444-grw5s2pf	938	20	from	from	IN
cord-256444-grw5s2pf	938	21	the	the	DT
cord-256444-grw5s2pf	938	22	DI	DI	NNP
cord-256444-grw5s2pf	938	23	RNA	RNA	NNP
cord-256444-grw5s2pf	938	24	in	in	IN
cord-256444-grw5s2pf	938	25	cis	cis	NNP
cord-256444-grw5s2pf	938	26	and	and	CC
cord-256444-grw5s2pf	938	27	from	from	IN
cord-256444-grw5s2pf	938	28	helper	helper	NN
cord-256444-grw5s2pf	938	29	virus	virus	NN
cord-256444-grw5s2pf	938	30	RNA	RNA	NNP
cord-256444-grw5s2pf	938	31	in	in	IN
cord-256444-grw5s2pf	938	32	trans	trans	NNP
cord-256444-grw5s2pf	938	33	.	.	.
cord-256444-grw5s2pf	939	1	When	when	WRB
cord-256444-grw5s2pf	939	2	this	this	DT
cord-256444-grw5s2pf	939	3	sequence	sequence	NN
cord-256444-grw5s2pf	939	4	is	be	VBZ
cord-256444-grw5s2pf	939	5	missing	miss	VBG
cord-256444-grw5s2pf	939	6	,	,	,
cord-256444-grw5s2pf	939	7	the	the	DT
cord-256444-grw5s2pf	939	8	leader	leader	NN
cord-256444-grw5s2pf	939	9	RNA	RNA	NNP
cord-256444-grw5s2pf	939	10	is	be	VBZ
cord-256444-grw5s2pf	939	11	derived	derive	VBN
cord-256444-grw5s2pf	939	12	exclusively	exclusively	RB
cord-256444-grw5s2pf	939	13	from	from	IN
cord-256444-grw5s2pf	939	14	the	the	DT
cord-256444-grw5s2pf	939	15	helper	helper	NN
cord-256444-grw5s2pf	939	16	virus	virus	NN
cord-256444-grw5s2pf	939	17	RNA	RNA	NNP
cord-256444-grw5s2pf	939	18	(	(	-LRB-
cord-256444-grw5s2pf	939	19	Zhang	Zhang	NNP
cord-256444-grw5s2pf	939	20	et	et	NNP
cord-256444-grw5s2pf	939	21	al	al	NNP
cord-256444-grw5s2pf	939	22	.	.	NNP
cord-256444-grw5s2pf	939	23	,	,	,
cord-256444-grw5s2pf	939	24	1994b	1994b	CD
cord-256444-grw5s2pf	939	25	)	)	-RRB-
cord-256444-grw5s2pf	939	26	.	.	.
cord-256444-grw5s2pf	940	1	Thus	thus	RB
cord-256444-grw5s2pf	940	2	,	,	,
cord-256444-grw5s2pf	940	3	this	this	DT
cord-256444-grw5s2pf	940	4	nine	nine	CD
cord-256444-grw5s2pf	940	5	-	-	HYPH
cord-256444-grw5s2pf	940	6	nucleotide	nucleotide	JJ
cord-256444-grw5s2pf	940	7	sequence	sequence	NN
cord-256444-grw5s2pf	940	8	appears	appear	VBZ
cord-256444-grw5s2pf	940	9	to	to	TO
cord-256444-grw5s2pf	940	10	regulate	regulate	VB
cord-256444-grw5s2pf	940	11	the	the	DT
cord-256444-grw5s2pf	940	12	mechanism	mechanism	NN
cord-256444-grw5s2pf	940	13	by	by	IN
cord-256444-grw5s2pf	940	14	which	which	WDT
cord-256444-grw5s2pf	940	15	the	the	DT
cord-256444-grw5s2pf	940	16	leader	leader	NN
cord-256444-grw5s2pf	940	17	RNA	RNA	NNP
cord-256444-grw5s2pf	940	18	is	be	VBZ
cord-256444-grw5s2pf	940	19	fused	fuse	VBN
cord-256444-grw5s2pf	940	20	t	t	NNP
cord-256444-grw5s2pf	940	21	o	o	NN
cord-256444-grw5s2pf	940	22	the	the	DT
cord-256444-grw5s2pf	940	23	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	940	24	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	940	25	.	.	.
cord-256444-grw5s2pf	941	1	These	these	DT
cord-256444-grw5s2pf	941	2	results	result	NNS
cord-256444-grw5s2pf	941	3	combined	combine	VBN
cord-256444-grw5s2pf	941	4	suggest	suggest	VBP
cord-256444-grw5s2pf	941	5	that	that	IN
cord-256444-grw5s2pf	941	6	multiple	multiple	JJ
cord-256444-grw5s2pf	941	7	RNA	RNA	NNP
cord-256444-grw5s2pf	941	8	regions	region	NNS
cord-256444-grw5s2pf	941	9	are	be	VBP
cord-256444-grw5s2pf	941	10	involved	involve	VBN
cord-256444-grw5s2pf	941	11	in	in	IN
cord-256444-grw5s2pf	941	12	the	the	DT
cord-256444-grw5s2pf	941	13	regulation	regulation	NN
cord-256444-grw5s2pf	941	14	of	of	IN
cord-256444-grw5s2pf	941	15	mRNA	mRNA	NNP
cord-256444-grw5s2pf	941	16	transcription	transcription	NN
cord-256444-grw5s2pf	941	17	.	.	.
cord-256444-grw5s2pf	942	1	However	however	RB
cord-256444-grw5s2pf	942	2	,	,	,
cord-256444-grw5s2pf	942	3	a	a	DT
cord-256444-grw5s2pf	942	4	recent	recent	JJ
cord-256444-grw5s2pf	942	5	study	study	NN
cord-256444-grw5s2pf	942	6	appears	appear	VBZ
cord-256444-grw5s2pf	942	7	to	to	TO
cord-256444-grw5s2pf	942	8	contradict	contradict	VB
cord-256444-grw5s2pf	942	9	the	the	DT
cord-256444-grw5s2pf	942	10	need	need	NN
cord-256444-grw5s2pf	942	11	of	of	IN
cord-256444-grw5s2pf	942	12	cis	cis	NNP
cord-256444-grw5s2pf	942	13	-	-	HYPH
cord-256444-grw5s2pf	942	14	acting	act	VBG
cord-256444-grw5s2pf	942	15	sequences	sequence	NNS
cord-256444-grw5s2pf	942	16	other	other	JJ
cord-256444-grw5s2pf	942	17	than	than	IN
cord-256444-grw5s2pf	942	18	the	the	DT
cord-256444-grw5s2pf	942	19	IGs	IGs	NNP
cord-256444-grw5s2pf	942	20	for	for	IN
cord-256444-grw5s2pf	942	21	mRNA	mRNA	NNP
cord-256444-grw5s2pf	942	22	transcription	transcription	NN
cord-256444-grw5s2pf	942	23	.	.	.
cord-256444-grw5s2pf	943	1	When	when	WRB
cord-256444-grw5s2pf	943	2	a	a	DT
cord-256444-grw5s2pf	943	3	negative	negative	JJ
cord-256444-grw5s2pf	943	4	-	-	HYPH
cord-256444-grw5s2pf	943	5	strand	strand	NN
cord-256444-grw5s2pf	943	6	RNA	RNA	NNP
cord-256444-grw5s2pf	943	7	containing	contain	VBG
cord-256444-grw5s2pf	943	8	only	only	RB
cord-256444-grw5s2pf	943	9	an	an	DT
cord-256444-grw5s2pf	943	10	IG	ig	NN
cord-256444-grw5s2pf	943	11	sequence	sequence	NN
cord-256444-grw5s2pf	943	12	of	of	IN
cord-256444-grw5s2pf	943	13	TGEV	TGEV	NNP
cord-256444-grw5s2pf	943	14	and	and	CC
cord-256444-grw5s2pf	943	15	a	a	DT
cord-256444-grw5s2pf	943	16	reporter	reporter	NN
cord-256444-grw5s2pf	943	17	gene	gene	NN
cord-256444-grw5s2pf	943	18	was	be	VBD
cord-256444-grw5s2pf	943	19	transcribed	transcribe	VBN
cord-256444-grw5s2pf	943	20	in	in	IN
cord-256444-grw5s2pf	943	21	situ	situ	NN
cord-256444-grw5s2pf	943	22	from	from	IN
cord-256444-grw5s2pf	943	23	a	a	DT
cord-256444-grw5s2pf	943	24	transfected	transfecte	VBN
cord-256444-grw5s2pf	943	25	cDNA	cdna	NN
cord-256444-grw5s2pf	943	26	by	by	IN
cord-256444-grw5s2pf	943	27	using	use	VBG
cord-256444-grw5s2pf	943	28	a	a	DT
cord-256444-grw5s2pf	943	29	recombinant	recombinant	JJ
cord-256444-grw5s2pf	943	30	vaccinia	vaccinia	NN
cord-256444-grw5s2pf	943	31	virus	virus	NN
cord-256444-grw5s2pf	943	32	-	-	HYPH
cord-256444-grw5s2pf	943	33	T7	T7	NNP
cord-256444-grw5s2pf	943	34	RNA	RNA	NNP
cord-256444-grw5s2pf	943	35	polymerase	polymerase	NN
cord-256444-grw5s2pf	943	36	expression	expression	NN
cord-256444-grw5s2pf	943	37	system	system	NN
cord-256444-grw5s2pf	943	38	,	,	,
cord-256444-grw5s2pf	943	39	this	this	DT
cord-256444-grw5s2pf	943	40	RNA	RNA	NNP
cord-256444-grw5s2pf	943	41	was	be	VBD
cord-256444-grw5s2pf	943	42	transcribed	transcribe	VBN
cord-256444-grw5s2pf	943	43	in	in	IN
cord-256444-grw5s2pf	943	44	the	the	DT
cord-256444-grw5s2pf	943	45	presence	presence	NN
cord-256444-grw5s2pf	943	46	of	of	IN
cord-256444-grw5s2pf	943	47	TGEV	TGEV	NNP
cord-256444-grw5s2pf	943	48	,	,	,
cord-256444-grw5s2pf	943	49	generating	generate	VBG
cord-256444-grw5s2pf	943	50	an	an	DT
cord-256444-grw5s2pf	943	51	mRNA	mrna	NN
cord-256444-grw5s2pf	943	52	with	with	IN
cord-256444-grw5s2pf	943	53	a	a	DT
cord-256444-grw5s2pf	943	54	correctly	correctly	RB
cord-256444-grw5s2pf	943	55	fused	fuse	VBN
cord-256444-grw5s2pf	943	56	TGEV	TGEV	NNP
cord-256444-grw5s2pf	943	57	leader	leader	NN
cord-256444-grw5s2pf	943	58	sequence	sequence	NN
cord-256444-grw5s2pf	943	59	(	(	-LRB-
cord-256444-grw5s2pf	943	60	Hiscox	Hiscox	NNP
cord-256444-grw5s2pf	943	61	et	et	FW
cord-256444-grw5s2pf	943	62	al	al	NNP
cord-256444-grw5s2pf	943	63	.	.	NNP
cord-256444-grw5s2pf	943	64	,	,	,
cord-256444-grw5s2pf	943	65	1995b	1995b	CD
cord-256444-grw5s2pf	943	66	)	)	-RRB-
cord-256444-grw5s2pf	943	67	.	.	.
cord-256444-grw5s2pf	944	1	The	the	DT
cord-256444-grw5s2pf	944	2	leadercontaining	leadercontaining	NN
cord-256444-grw5s2pf	944	3	mRNA	mrna	NN
cord-256444-grw5s2pf	944	4	could	could	MD
cord-256444-grw5s2pf	944	5	have	have	VB
cord-256444-grw5s2pf	944	6	been	be	VBN
cord-256444-grw5s2pf	944	7	generated	generate	VBN
cord-256444-grw5s2pf	944	8	by	by	IN
cord-256444-grw5s2pf	944	9	either	either	DT
cord-256444-grw5s2pf	944	10	of	of	IN
cord-256444-grw5s2pf	944	11	the	the	DT
cord-256444-grw5s2pf	944	12	transcription	transcription	NN
cord-256444-grw5s2pf	944	13	mechanisms	mechanism	NNS
cord-256444-grw5s2pf	944	14	described	describe	VBN
cord-256444-grw5s2pf	944	15	(	(	-LRB-
cord-256444-grw5s2pf	944	16	Section	section	NN
cord-256444-grw5s2pf	944	17	V	V	NNP
cord-256444-grw5s2pf	944	18	,	,	,
cord-256444-grw5s2pf	944	19	E,4,a	E,4,a	NNP
cord-256444-grw5s2pf	944	20	or	or	CC
cord-256444-grw5s2pf	944	21	Section	Section	NNP
cord-256444-grw5s2pf	944	22	V	V	NNP
cord-256444-grw5s2pf	944	23	,	,	,
cord-256444-grw5s2pf	944	24	E,4,b	e,4,b	NN
cord-256444-grw5s2pf	944	25	)	)	-RRB-
cord-256444-grw5s2pf	944	26	above	above	RB
cord-256444-grw5s2pf	944	27	.	.	.
cord-256444-grw5s2pf	945	1	This	this	DT
cord-256444-grw5s2pf	945	2	study	study	NN
cord-256444-grw5s2pf	945	3	suggests	suggest	VBZ
cord-256444-grw5s2pf	945	4	that	that	IN
cord-256444-grw5s2pf	945	5	this	this	DT
cord-256444-grw5s2pf	945	6	negative	negative	JJ
cord-256444-grw5s2pf	945	7	-	-	HYPH
cord-256444-grw5s2pf	945	8	strand	strand	NN
cord-256444-grw5s2pf	945	9	IG	ig	NN
cord-256444-grw5s2pf	945	10	site	site	NN
cord-256444-grw5s2pf	945	11	is	be	VBZ
cord-256444-grw5s2pf	945	12	sufficient	sufficient	JJ
cord-256444-grw5s2pf	945	13	for	for	IN
cord-256444-grw5s2pf	945	14	transcription	transcription	NN
cord-256444-grw5s2pf	945	15	.	.	.
cord-256444-grw5s2pf	946	1	However	however	RB
cord-256444-grw5s2pf	946	2	,	,	,
cord-256444-grw5s2pf	946	3	it	-PRON-	PRP
cord-256444-grw5s2pf	946	4	is	be	VBZ
cord-256444-grw5s2pf	946	5	possible	possible	JJ
cord-256444-grw5s2pf	946	6	that	that	IN
cord-256444-grw5s2pf	946	7	this	this	DT
cord-256444-grw5s2pf	946	8	activity	activity	NN
cord-256444-grw5s2pf	946	9	represents	represent	VBZ
cord-256444-grw5s2pf	946	10	a	a	DT
cord-256444-grw5s2pf	946	11	basal	basal	NN
cord-256444-grw5s2pf	946	12	level	level	NN
cord-256444-grw5s2pf	946	13	of	of	IN
cord-256444-grw5s2pf	946	14	transcription	transcription	NN
cord-256444-grw5s2pf	946	15	and	and	CC
cord-256444-grw5s2pf	946	16	that	that	IN
cord-256444-grw5s2pf	946	17	other	other	JJ
cord-256444-grw5s2pf	946	18	cis	cis	NNP
cord-256444-grw5s2pf	946	19	-	-	HYPH
cord-256444-grw5s2pf	946	20	acting	acting	NN
cord-256444-grw5s2pf	946	21	sequences	sequence	NNS
cord-256444-grw5s2pf	946	22	may	may	MD
cord-256444-grw5s2pf	946	23	enhance	enhance	VB
cord-256444-grw5s2pf	946	24	the	the	DT
cord-256444-grw5s2pf	946	25	efficiency	efficiency	NN
cord-256444-grw5s2pf	946	26	of	of	IN
cord-256444-grw5s2pf	946	27	transcription	transcription	NN
cord-256444-grw5s2pf	946	28	.	.	.
cord-256444-grw5s2pf	947	1	The	the	DT
cord-256444-grw5s2pf	947	2	application	application	NN
cord-256444-grw5s2pf	947	3	of	of	IN
cord-256444-grw5s2pf	947	4	inhibitors	inhibitor	NNS
cord-256444-grw5s2pf	947	5	of	of	IN
cord-256444-grw5s2pf	947	6	protein	protein	NN
cord-256444-grw5s2pf	947	7	synthesis	synthesis	NN
cord-256444-grw5s2pf	947	8	at	at	IN
cord-256444-grw5s2pf	947	9	any	any	DT
cord-256444-grw5s2pf	947	10	time	time	NN
cord-256444-grw5s2pf	947	11	during	during	IN
cord-256444-grw5s2pf	947	12	the	the	DT
cord-256444-grw5s2pf	947	13	viral	viral	JJ
cord-256444-grw5s2pf	947	14	life	life	NN
cord-256444-grw5s2pf	947	15	cycle	cycle	NN
cord-256444-grw5s2pf	947	16	inhibits	inhibit	VBZ
cord-256444-grw5s2pf	947	17	viral	viral	JJ
cord-256444-grw5s2pf	947	18	RNA	RNA	NNP
cord-256444-grw5s2pf	947	19	synthesis	synthesis	NN
cord-256444-grw5s2pf	947	20	,	,	,
cord-256444-grw5s2pf	947	21	suggesting	suggest	VBG
cord-256444-grw5s2pf	947	22	that	that	IN
cord-256444-grw5s2pf	947	23	continuous	continuous	JJ
cord-256444-grw5s2pf	947	24	protein	protein	NN
cord-256444-grw5s2pf	947	25	synthesis	synthesis	NN
cord-256444-grw5s2pf	947	26	is	be	VBZ
cord-256444-grw5s2pf	947	27	required	require	VBN
cord-256444-grw5s2pf	947	28	for	for	IN
cord-256444-grw5s2pf	947	29	RNA	RNA	NNP
cord-256444-grw5s2pf	947	30	synthesis	synthesis	NN
cord-256444-grw5s2pf	947	31	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	947	32	and	and	CC
cord-256444-grw5s2pf	947	33	Sawicki	Sawicki	NNP
cord-256444-grw5s2pf	947	34	,	,	,
cord-256444-grw5s2pf	947	35	1986	1986	CD
cord-256444-grw5s2pf	947	36	)	)	-RRB-
cord-256444-grw5s2pf	947	37	.	.	.
cord-256444-grw5s2pf	948	1	A	a	DT
cord-256444-grw5s2pf	948	2	similar	similar	JJ
cord-256444-grw5s2pf	948	3	observation	observation	NN
cord-256444-grw5s2pf	948	4	has	have	VBZ
cord-256444-grw5s2pf	948	5	been	be	VBN
cord-256444-grw5s2pf	948	6	made	make	VBN
cord-256444-grw5s2pf	948	7	using	use	VBG
cord-256444-grw5s2pf	948	8	an	an	DT
cord-256444-grw5s2pf	948	9	inhibitor	inhibitor	NN
cord-256444-grw5s2pf	948	10	of	of	IN
cord-256444-grw5s2pf	948	11	cysteine	cysteine	NN
cord-256444-grw5s2pf	948	12	proteases	protease	NNS
cord-256444-grw5s2pf	948	13	,	,	,
cord-256444-grw5s2pf	948	14	which	which	WDT
cord-256444-grw5s2pf	948	15	inhibits	inhibit	VBZ
cord-256444-grw5s2pf	948	16	a	a	DT
cord-256444-grw5s2pf	948	17	specific	specific	JJ
cord-256444-grw5s2pf	948	18	step	step	NN
cord-256444-grw5s2pf	948	19	of	of	IN
cord-256444-grw5s2pf	948	20	the	the	DT
cord-256444-grw5s2pf	948	21	processing	processing	NN
cord-256444-grw5s2pf	948	22	of	of	IN
cord-256444-grw5s2pf	948	23	gene	gene	NN
cord-256444-grw5s2pf	948	24	l	l	NNP
cord-256444-grw5s2pf	948	25	a	a	DT
cord-256444-grw5s2pf	948	26	products	product	NNS
cord-256444-grw5s2pf	948	27	of	of	IN
cord-256444-grw5s2pf	948	28	MHV	MHV	NNP
cord-256444-grw5s2pf	948	29	(	(	-LRB-
cord-256444-grw5s2pf	948	30	see	see	VB
cord-256444-grw5s2pf	948	31	Section	section	NN
cord-256444-grw5s2pf	948	32	V	V	NNP
cord-256444-grw5s2pf	948	33	,	,	,
cord-256444-grw5s2pf	948	34	G,2	G,2	NNP
cord-256444-grw5s2pf	948	35	)	)	-RRB-
cord-256444-grw5s2pf	948	36	,	,	,
cord-256444-grw5s2pf	948	37	suggesting	suggest	VBG
cord-256444-grw5s2pf	948	38	that	that	IN
cord-256444-grw5s2pf	948	39	continuous	continuous	JJ
cord-256444-grw5s2pf	948	40	production	production	NN
cord-256444-grw5s2pf	948	41	of	of	IN
cord-256444-grw5s2pf	948	42	polymerase	polymerase	NN
cord-256444-grw5s2pf	948	43	is	be	VBZ
cord-256444-grw5s2pf	948	44	required	require	VBN
cord-256444-grw5s2pf	948	45	for	for	IN
cord-256444-grw5s2pf	948	46	viral	viral	JJ
cord-256444-grw5s2pf	948	47	RNA	RNA	NNP
cord-256444-grw5s2pf	948	48	synthesis	synthesis	NN
cord-256444-grw5s2pf	948	49	.	.	.
cord-256444-grw5s2pf	949	1	The	the	DT
cord-256444-grw5s2pf	949	2	precise	precise	JJ
cord-256444-grw5s2pf	949	3	nature	nature	NN
cord-256444-grw5s2pf	949	4	of	of	IN
cord-256444-grw5s2pf	949	5	the	the	DT
cord-256444-grw5s2pf	949	6	viral	viral	JJ
cord-256444-grw5s2pf	949	7	proteins	protein	NNS
cord-256444-grw5s2pf	949	8	involved	involve	VBN
cord-256444-grw5s2pf	949	9	has	have	VBZ
cord-256444-grw5s2pf	949	10	yet	yet	RB
cord-256444-grw5s2pf	949	11	to	to	TO
cord-256444-grw5s2pf	949	12	be	be	VB
cord-256444-grw5s2pf	949	13	determined	determine	VBN
cord-256444-grw5s2pf	949	14	.	.	.
cord-256444-grw5s2pf	950	1	Temperature	temperature	NN
cord-256444-grw5s2pf	950	2	-	-	HYPH
cord-256444-grw5s2pf	950	3	sensitive	sensitive	JJ
cord-256444-grw5s2pf	950	4	mutants	mutant	NNS
cord-256444-grw5s2pf	950	5	of	of	IN
cord-256444-grw5s2pf	950	6	MHV	MHV	NNP
cord-256444-grw5s2pf	950	7	that	that	WDT
cord-256444-grw5s2pf	950	8	are	be	VBP
cord-256444-grw5s2pf	950	9	defective	defective	JJ
cord-256444-grw5s2pf	950	10	in	in	IN
cord-256444-grw5s2pf	950	11	RNA	RNA	NNP
cord-256444-grw5s2pf	950	12	synthesis	synthesis	NN
cord-256444-grw5s2pf	950	13	at	at	IN
cord-256444-grw5s2pf	950	14	the	the	DT
cord-256444-grw5s2pf	950	15	nonpermissive	nonpermissive	JJ
cord-256444-grw5s2pf	950	16	temperature	temperature	NN
cord-256444-grw5s2pf	950	17	have	have	VBP
cord-256444-grw5s2pf	950	18	been	be	VBN
cord-256444-grw5s2pf	950	19	divided	divide	VBN
cord-256444-grw5s2pf	950	20	into	into	IN
cord-256444-grw5s2pf	950	21	at	at	RB
cord-256444-grw5s2pf	950	22	least	least	RBS
cord-256444-grw5s2pf	950	23	five	five	CD
cord-256444-grw5s2pf	950	24	complementation	complementation	NN
cord-256444-grw5s2pf	950	25	groups	group	NNS
cord-256444-grw5s2pf	950	26	,	,	,
cord-256444-grw5s2pf	950	27	indicating	indicate	VBG
cord-256444-grw5s2pf	950	28	that	that	IN
cord-256444-grw5s2pf	950	29	at	at	RB
cord-256444-grw5s2pf	950	30	least	least	RBS
cord-256444-grw5s2pf	950	31	five	five	CD
cord-256444-grw5s2pf	950	32	proteins	protein	NNS
cord-256444-grw5s2pf	950	33	are	be	VBP
cord-256444-grw5s2pf	950	34	involved	involve	VBN
cord-256444-grw5s2pf	950	35	in	in	IN
cord-256444-grw5s2pf	950	36	viral	viral	JJ
cord-256444-grw5s2pf	950	37	RNA	RNA	NNP
cord-256444-grw5s2pf	950	38	synthesis	synthesis	NN
cord-256444-grw5s2pf	950	39	(	(	-LRB-
cord-256444-grw5s2pf	950	40	Leibowitz	Leibowitz	NNP
cord-256444-grw5s2pf	950	41	et	et	NNP
cord-256444-grw5s2pf	950	42	al	al	NNP
cord-256444-grw5s2pf	950	43	.	.	NNP
cord-256444-grw5s2pf	950	44	,	,	,
cord-256444-grw5s2pf	950	45	1982a	1982a	CD
cord-256444-grw5s2pf	950	46	;	;	:
cord-256444-grw5s2pf	950	47	Baric	Baric	NNP
cord-256444-grw5s2pf	950	48	et	et	NNP
cord-256444-grw5s2pf	950	49	al	al	NNP
cord-256444-grw5s2pf	950	50	.	.	NNP
cord-256444-grw5s2pf	950	51	,	,	,
cord-256444-grw5s2pf	950	52	1990	1990	CD
cord-256444-grw5s2pf	950	53	)	)	-RRB-
cord-256444-grw5s2pf	950	54	(	(	-LRB-
cord-256444-grw5s2pf	950	55	see	see	VB
cord-256444-grw5s2pf	950	56	Fig	Fig	NNP
cord-256444-grw5s2pf	950	57	.	.	.
cord-256444-grw5s2pf	950	58	6	6	CD
cord-256444-grw5s2pf	950	59	)	)	-RRB-
cord-256444-grw5s2pf	950	60	.	.	.
cord-256444-grw5s2pf	951	1	All	all	DT
cord-256444-grw5s2pf	951	2	of	of	IN
cord-256444-grw5s2pf	951	3	these	these	DT
cord-256444-grw5s2pf	951	4	complementation	complementation	NN
cord-256444-grw5s2pf	951	5	groups	group	NNS
cord-256444-grw5s2pf	951	6	are	be	VBP
cord-256444-grw5s2pf	951	7	mapped	map	VBN
cord-256444-grw5s2pf	951	8	within	within	IN
cord-256444-grw5s2pf	951	9	the	the	DT
cord-256444-grw5s2pf	951	10	gene	gene	NN
cord-256444-grw5s2pf	951	11	1	1	CD
cord-256444-grw5s2pf	951	12	region	region	NN
cord-256444-grw5s2pf	951	13	(	(	-LRB-
cord-256444-grw5s2pf	951	14	including	include	VBG
cord-256444-grw5s2pf	951	15	both	both	CC
cord-256444-grw5s2pf	951	16	l	l	NNP
cord-256444-grw5s2pf	951	17	a	a	NN
cord-256444-grw5s2pf	951	18	and	and	CC
cord-256444-grw5s2pf	951	19	lb	lb	CD
cord-256444-grw5s2pf	951	20	)	)	-RRB-
cord-256444-grw5s2pf	951	21	.	.	.
cord-256444-grw5s2pf	952	1	Sequence	sequence	NN
cord-256444-grw5s2pf	952	2	analysis	analysis	NN
cord-256444-grw5s2pf	952	3	showed	show	VBD
cord-256444-grw5s2pf	952	4	that	that	IN
cord-256444-grw5s2pf	952	5	gene	gene	NN
cord-256444-grw5s2pf	952	6	l	l	NNP
cord-256444-grw5s2pf	952	7	b	b	NNP
cord-256444-grw5s2pf	952	8	contains	contain	VBZ
cord-256444-grw5s2pf	952	9	an	an	DT
cord-256444-grw5s2pf	952	10	RNA	RNA	NNP
cord-256444-grw5s2pf	952	11	polymerase	polymerase	NN
cord-256444-grw5s2pf	952	12	motif	motif	NN
cord-256444-grw5s2pf	952	13	(	(	-LRB-
cord-256444-grw5s2pf	952	14	Gorbalenya	Gorbalenya	NNP
cord-256444-grw5s2pf	952	15	et	et	NNP
cord-256444-grw5s2pf	952	16	al	al	NNP
cord-256444-grw5s2pf	952	17	.	.	NNP
cord-256444-grw5s2pf	952	18	,	,	,
cord-256444-grw5s2pf	952	19	198913	198913	CD
cord-256444-grw5s2pf	952	20	;	;	:
cord-256444-grw5s2pf	952	21	Lee	Lee	NNP
cord-256444-grw5s2pf	952	22	et	et	NNP
cord-256444-grw5s2pf	952	23	al	al	NNP
cord-256444-grw5s2pf	952	24	.	.	NNP
cord-256444-grw5s2pf	952	25	,	,	,
cord-256444-grw5s2pf	952	26	1991	1991	CD
cord-256444-grw5s2pf	952	27	)	)	-RRB-
cord-256444-grw5s2pf	952	28	.	.	.
cord-256444-grw5s2pf	953	1	Polymerase	polymerase	NN
cord-256444-grw5s2pf	953	2	activities	activity	NNS
cord-256444-grw5s2pf	953	3	have	have	VBP
cord-256444-grw5s2pf	953	4	been	be	VBN
cord-256444-grw5s2pf	953	5	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	953	6	in	in	IN
cord-256444-grw5s2pf	953	7	membrane	membrane	NN
cord-256444-grw5s2pf	953	8	fractions	fraction	NNS
cord-256444-grw5s2pf	953	9	of	of	IN
cord-256444-grw5s2pf	953	10	BCV	BCV	NNP
cord-256444-grw5s2pf	953	11	-	-	:
cord-256444-grw5s2pf	953	12	and	and	CC
cord-256444-grw5s2pf	953	13	MHV	MHV	NNP
cord-256444-grw5s2pf	953	14	-	-	HYPH
cord-256444-grw5s2pf	953	15	infected	infect	VBN
cord-256444-grw5s2pf	953	16	cells	cell	NNS
cord-256444-grw5s2pf	953	17	Dennis	Dennis	NNP
cord-256444-grw5s2pf	953	18	and	and	CC
cord-256444-grw5s2pf	953	19	Brian	Brian	NNP
cord-256444-grw5s2pf	953	20	,	,	,
cord-256444-grw5s2pf	953	21	1982	1982	CD
cord-256444-grw5s2pf	953	22	)	)	-RRB-
cord-256444-grw5s2pf	953	23	,	,	,
cord-256444-grw5s2pf	953	24	and	and	CC
cord-256444-grw5s2pf	953	25	several	several	JJ
cord-256444-grw5s2pf	953	26	in	in	IN
cord-256444-grw5s2pf	953	27	vitro	vitro	FW
cord-256444-grw5s2pf	953	28	RNA	RNA	NNP
cord-256444-grw5s2pf	953	29	synthesis	synthesis	NN
cord-256444-grw5s2pf	953	30	systems	system	NNS
cord-256444-grw5s2pf	953	31	have	have	VBP
cord-256444-grw5s2pf	953	32	been	be	VBN
cord-256444-grw5s2pf	953	33	reported	report	VBN
cord-256444-grw5s2pf	954	1	(	(	-LRB-
cord-256444-grw5s2pf	954	2	Compton	Compton	NNP
cord-256444-grw5s2pf	954	3	et	et	NNP
cord-256444-grw5s2pf	954	4	al	al	NNP
cord-256444-grw5s2pf	954	5	.	.	NNP
cord-256444-grw5s2pf	954	6	,	,	,
cord-256444-grw5s2pf	954	7	1987	1987	CD
cord-256444-grw5s2pf	954	8	;	;	:
cord-256444-grw5s2pf	954	9	Baker	Baker	NNP
cord-256444-grw5s2pf	954	10	and	and	CC
cord-256444-grw5s2pf	954	11	Lai	Lai	NNP
cord-256444-grw5s2pf	954	12	,	,	,
cord-256444-grw5s2pf	954	13	1990	1990	CD
cord-256444-grw5s2pf	954	14	)	)	-RRB-
cord-256444-grw5s2pf	954	15	;	;	:
cord-256444-grw5s2pf	954	16	however	however	RB
cord-256444-grw5s2pf	954	17	,	,	,
cord-256444-grw5s2pf	954	18	the	the	DT
cord-256444-grw5s2pf	954	19	nature	nature	NN
cord-256444-grw5s2pf	954	20	of	of	IN
cord-256444-grw5s2pf	954	21	polymerases	polymerase	NNS
cord-256444-grw5s2pf	954	22	in	in	IN
cord-256444-grw5s2pf	954	23	these	these	DT
cord-256444-grw5s2pf	954	24	systems	system	NNS
cord-256444-grw5s2pf	954	25	has	have	VBZ
cord-256444-grw5s2pf	954	26	not	not	RB
cord-256444-grw5s2pf	954	27	been	be	VBN
cord-256444-grw5s2pf	954	28	identified	identify	VBN
cord-256444-grw5s2pf	954	29	.	.	.
cord-256444-grw5s2pf	955	1	In	in	IN
cord-256444-grw5s2pf	955	2	one	one	CD
cord-256444-grw5s2pf	955	3	study	study	NN
cord-256444-grw5s2pf	955	4	,	,	,
cord-256444-grw5s2pf	955	5	it	-PRON-	PRP
cord-256444-grw5s2pf	955	6	was	be	VBD
cord-256444-grw5s2pf	955	7	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	955	8	that	that	IN
cord-256444-grw5s2pf	955	9	the	the	DT
cord-256444-grw5s2pf	955	10	antibodies	antibody	NNS
cord-256444-grw5s2pf	955	11	against	against	IN
cord-256444-grw5s2pf	955	12	the	the	DT
cord-256444-grw5s2pf	955	13	N	N	NNP
cord-256444-grw5s2pf	955	14	protein	protein	NN
cord-256444-grw5s2pf	955	15	could	could	MD
cord-256444-grw5s2pf	955	16	inhibit	inhibit	VB
cord-256444-grw5s2pf	955	17	RNA	RNA	NNP
cord-256444-grw5s2pf	955	18	synthesis	synthesis	NN
cord-256444-grw5s2pf	955	19	,	,	,
cord-256444-grw5s2pf	955	20	suggesting	suggest	VBG
cord-256444-grw5s2pf	955	21	that	that	IN
cord-256444-grw5s2pf	955	22	N	n	CD
cord-256444-grw5s2pf	955	23	protein	protein	NN
cord-256444-grw5s2pf	955	24	may	may	MD
cord-256444-grw5s2pf	955	25	be	be	VB
cord-256444-grw5s2pf	955	26	involved	involve	VBN
cord-256444-grw5s2pf	955	27	in	in	IN
cord-256444-grw5s2pf	955	28	RNA	RNA	NNP
cord-256444-grw5s2pf	955	29	synthesis	synthesis	NN
cord-256444-grw5s2pf	955	30	(	(	-LRB-
cord-256444-grw5s2pf	955	31	Compton	Compton	NNP
cord-256444-grw5s2pf	955	32	et	et	NNP
cord-256444-grw5s2pf	955	33	al	al	NNP
cord-256444-grw5s2pf	955	34	.	.	NNP
cord-256444-grw5s2pf	955	35	,	,	,
cord-256444-grw5s2pf	955	36	1987	1987	CD
cord-256444-grw5s2pf	955	37	)	)	-RRB-
cord-256444-grw5s2pf	955	38	.	.	.
cord-256444-grw5s2pf	956	1	In	in	IN
cord-256444-grw5s2pf	956	2	addition	addition	NN
cord-256444-grw5s2pf	956	3	to	to	IN
cord-256444-grw5s2pf	956	4	viral	viral	JJ
cord-256444-grw5s2pf	956	5	proteins	protein	NNS
cord-256444-grw5s2pf	956	6	,	,	,
cord-256444-grw5s2pf	956	7	cellular	cellular	JJ
cord-256444-grw5s2pf	956	8	factors	factor	NNS
cord-256444-grw5s2pf	956	9	may	may	MD
cord-256444-grw5s2pf	956	10	also	also	RB
cord-256444-grw5s2pf	956	11	be	be	VB
cord-256444-grw5s2pf	956	12	involved	involve	VBN
cord-256444-grw5s2pf	956	13	in	in	IN
cord-256444-grw5s2pf	956	14	RNA	RNA	NNP
cord-256444-grw5s2pf	956	15	synthesis	synthesis	NN
cord-256444-grw5s2pf	956	16	.	.	.
cord-256444-grw5s2pf	957	1	Several	several	JJ
cord-256444-grw5s2pf	957	2	cellular	cellular	JJ
cord-256444-grw5s2pf	957	3	proteins	protein	NNS
cord-256444-grw5s2pf	957	4	have	have	VBP
cord-256444-grw5s2pf	957	5	been	be	VBN
cord-256444-grw5s2pf	957	6	shown	show	VBN
cord-256444-grw5s2pf	957	7	to	to	TO
cord-256444-grw5s2pf	957	8	bind	bind	VB
cord-256444-grw5s2pf	957	9	to	to	IN
cord-256444-grw5s2pf	957	10	the	the	DT
cord-256444-grw5s2pf	957	11	regulatory	regulatory	JJ
cord-256444-grw5s2pf	957	12	elements	element	NNS
cord-256444-grw5s2pf	957	13	of	of	IN
cord-256444-grw5s2pf	957	14	MHV	MHV	NNP
cord-256444-grw5s2pf	957	15	RNA	RNA	NNP
cord-256444-grw5s2pf	957	16	,	,	,
cord-256444-grw5s2pf	957	17	including	include	VBG
cord-256444-grw5s2pf	957	18	the	the	DT
cord-256444-grw5s2pf	957	19	5	5	CD
cord-256444-grw5s2pf	957	20	'	'	''
cord-256444-grw5s2pf	957	21	and	and	CC
cord-256444-grw5s2pf	957	22	3	3	CD
cord-256444-grw5s2pf	957	23	'	'	POS
cord-256444-grw5s2pf	957	24	ends	end	NNS
cord-256444-grw5s2pf	957	25	of	of	IN
cord-256444-grw5s2pf	957	26	the	the	DT
cord-256444-grw5s2pf	957	27	genomic	genomic	JJ
cord-256444-grw5s2pf	957	28	RNA	RNA	NNP
cord-256444-grw5s2pf	957	29	and	and	CC
cord-256444-grw5s2pf	957	30	the	the	DT
cord-256444-grw5s2pf	957	31	3	3	CD
cord-256444-grw5s2pf	957	32	'	'	NN
cord-256444-grw5s2pf	957	33	end	end	NN
cord-256444-grw5s2pf	957	34	of	of	IN
cord-256444-grw5s2pf	957	35	the	the	DT
cord-256444-grw5s2pf	957	36	negative	negative	JJ
cord-256444-grw5s2pf	957	37	-	-	HYPH
cord-256444-grw5s2pf	957	38	strand	strand	NN
cord-256444-grw5s2pf	957	39	RNA	RNA	NNP
cord-256444-grw5s2pf	957	40	and	and	CC
cord-256444-grw5s2pf	957	41	IG	IG	NNP
cord-256444-grw5s2pf	957	42	sites	site	NNS
cord-256444-grw5s2pf	957	43	Yu	Yu	NNP
cord-256444-grw5s2pf	957	44	and	and	CC
cord-256444-grw5s2pf	957	45	Leibowitz	Leibowitz	NNP
cord-256444-grw5s2pf	957	46	,	,	,
cord-256444-grw5s2pf	957	47	1995a	1995a	CD
cord-256444-grw5s2pf	957	48	,	,	,
cord-256444-grw5s2pf	957	49	b	b	LS
cord-256444-grw5s2pf	957	50	;	;	:
cord-256444-grw5s2pf	957	51	Zhang	Zhang	NNP
cord-256444-grw5s2pf	957	52	and	and	CC
cord-256444-grw5s2pf	957	53	Lai	Lai	NNP
cord-256444-grw5s2pf	957	54	,	,	,
cord-256444-grw5s2pf	957	55	1995	1995	CD
cord-256444-grw5s2pf	957	56	)	)	-RRB-
cord-256444-grw5s2pf	957	57	.	.	.
cord-256444-grw5s2pf	958	1	The	the	DT
cord-256444-grw5s2pf	958	2	binding	bind	VBG
cord-256444-grw5s2pf	958	3	sites	site	NNS
cord-256444-grw5s2pf	958	4	for	for	IN
cord-256444-grw5s2pf	958	5	the	the	DT
cord-256444-grw5s2pf	958	6	cellular	cellular	JJ
cord-256444-grw5s2pf	958	7	proteins	protein	NNS
cord-256444-grw5s2pf	958	8	at	at	IN
cord-256444-grw5s2pf	958	9	the	the	DT
cord-256444-grw5s2pf	958	10	5	5	CD
cord-256444-grw5s2pf	958	11	'	'	NN
cord-256444-grw5s2pf	958	12	end	end	NN
cord-256444-grw5s2pf	958	13	of	of	IN
cord-256444-grw5s2pf	958	14	genomic	genomic	JJ
cord-256444-grw5s2pf	958	15	RNA	RNA	NNP
cord-256444-grw5s2pf	958	16	and	and	CC
cord-256444-grw5s2pf	958	17	the	the	DT
cord-256444-grw5s2pf	958	18	3	3	CD
cord-256444-grw5s2pf	958	19	'	'	NN
cord-256444-grw5s2pf	958	20	end	end	NN
cord-256444-grw5s2pf	958	21	of	of	IN
cord-256444-grw5s2pf	958	22	negative	negative	JJ
cord-256444-grw5s2pf	958	23	-	-	HYPH
cord-256444-grw5s2pf	958	24	strand	strand	NN
cord-256444-grw5s2pf	958	25	RNA	RNA	NNP
cord-256444-grw5s2pf	958	26	are	be	VBP
cord-256444-grw5s2pf	958	27	complementary	complementary	JJ
cord-256444-grw5s2pf	958	28	.	.	.
cord-256444-grw5s2pf	959	1	The	the	DT
cord-256444-grw5s2pf	959	2	protein	protein	NN
cord-256444-grw5s2pf	959	3	p35	p35	NN
cord-256444-grw5s2pf	959	4	,	,	,
cord-256444-grw5s2pf	959	5	which	which	WDT
cord-256444-grw5s2pf	959	6	binds	bind	VBZ
cord-256444-grw5s2pf	959	7	to	to	IN
cord-256444-grw5s2pf	959	8	the	the	DT
cord-256444-grw5s2pf	959	9	negative	negative	JJ
cord-256444-grw5s2pf	959	10	-	-	HYPH
cord-256444-grw5s2pf	959	11	strand	strand	NN
cord-256444-grw5s2pf	959	12	leader	leader	NN
cord-256444-grw5s2pf	959	13	sequence	sequence	NN
cord-256444-grw5s2pf	959	14	and	and	CC
cord-256444-grw5s2pf	959	15	the	the	DT
cord-256444-grw5s2pf	959	16	IG	IG	NNP
cord-256444-grw5s2pf	959	17	site	site	NN
cord-256444-grw5s2pf	959	18	,	,	,
cord-256444-grw5s2pf	959	19	is	be	VBZ
cord-256444-grw5s2pf	959	20	particularly	particularly	RB
cord-256444-grw5s2pf	959	21	interesting	interesting	JJ
cord-256444-grw5s2pf	959	22	.	.	.
cord-256444-grw5s2pf	960	1	Site	site	NN
cord-256444-grw5s2pf	960	2	-	-	HYPH
cord-256444-grw5s2pf	960	3	specific	specific	JJ
cord-256444-grw5s2pf	960	4	mutations	mutation	NNS
cord-256444-grw5s2pf	960	5	of	of	IN
cord-256444-grw5s2pf	960	6	the	the	DT
cord-256444-grw5s2pf	960	7	IG	IG	NNP
cord-256444-grw5s2pf	960	8	site	site	NN
cord-256444-grw5s2pf	960	9	affected	affect	VBD
cord-256444-grw5s2pf	960	10	the	the	DT
cord-256444-grw5s2pf	960	11	binding	binding	NN
cord-256444-grw5s2pf	960	12	of	of	IN
cord-256444-grw5s2pf	960	13	this	this	DT
cord-256444-grw5s2pf	960	14	protein	protein	NN
cord-256444-grw5s2pf	960	15	and	and	CC
cord-256444-grw5s2pf	960	16	the	the	DT
cord-256444-grw5s2pf	960	17	efficiency	efficiency	NN
cord-256444-grw5s2pf	960	18	of	of	IN
cord-256444-grw5s2pf	960	19	RNA	RNA	NNP
cord-256444-grw5s2pf	960	20	transcription	transcription	NN
cord-256444-grw5s2pf	960	21	to	to	IN
cord-256444-grw5s2pf	960	22	the	the	DT
cord-256444-grw5s2pf	960	23	same	same	JJ
cord-256444-grw5s2pf	960	24	extent	extent	NN
cord-256444-grw5s2pf	960	25	,	,	,
cord-256444-grw5s2pf	960	26	suggesting	suggest	VBG
cord-256444-grw5s2pf	960	27	that	that	IN
cord-256444-grw5s2pf	960	28	the	the	DT
cord-256444-grw5s2pf	960	29	binding	binding	NN
cord-256444-grw5s2pf	960	30	of	of	IN
cord-256444-grw5s2pf	960	31	this	this	DT
cord-256444-grw5s2pf	960	32	protein	protein	NN
cord-256444-grw5s2pf	960	33	is	be	VBZ
cord-256444-grw5s2pf	960	34	required	require	VBN
cord-256444-grw5s2pf	960	35	for	for	IN
cord-256444-grw5s2pf	960	36	RNA	RNA	NNP
cord-256444-grw5s2pf	960	37	transcription	transcription	NN
cord-256444-grw5s2pf	960	38	.	.	.
cord-256444-grw5s2pf	961	1	This	this	DT
cord-256444-grw5s2pf	961	2	protein	protein	NN
cord-256444-grw5s2pf	961	3	recently	recently	RB
cord-256444-grw5s2pf	961	4	has	have	VBZ
cord-256444-grw5s2pf	961	5	been	be	VBN
cord-256444-grw5s2pf	961	6	identified	identify	VBN
cord-256444-grw5s2pf	961	7	as	as	IN
cord-256444-grw5s2pf	961	8	hnRNP	hnrnp	DT
cord-256444-grw5s2pf	961	9	A1	a1	NN
cord-256444-grw5s2pf	961	10	(	(	-LRB-
cord-256444-grw5s2pf	961	11	H.-P.	H.-P.	NNP
cord-256444-grw5s2pf	961	12	Li	Li	NNP
cord-256444-grw5s2pf	961	13	and	and	CC
cord-256444-grw5s2pf	961	14	M.	M.	NNP
cord-256444-grw5s2pf	961	15	M.	M.	NNP
cord-256444-grw5s2pf	961	16	C.	C.	NNP
cord-256444-grw5s2pf	961	17	Lai	Lai	NNP
cord-256444-grw5s2pf	961	18	,	,	,
cord-256444-grw5s2pf	961	19	unpublished	unpublished	JJ
cord-256444-grw5s2pf	961	20	observation	observation	NN
cord-256444-grw5s2pf	961	21	)	)	-RRB-
cord-256444-grw5s2pf	961	22	.	.	.
cord-256444-grw5s2pf	962	1	The	the	DT
cord-256444-grw5s2pf	962	2	mutations	mutation	NNS
cord-256444-grw5s2pf	962	3	at	at	IN
cord-256444-grw5s2pf	962	4	the	the	DT
cord-256444-grw5s2pf	962	5	3	3	CD
cord-256444-grw5s2pf	962	6	'	'	NN
cord-256444-grw5s2pf	962	7	end	end	NN
cord-256444-grw5s2pf	962	8	of	of	IN
cord-256444-grw5s2pf	962	9	the	the	DT
cord-256444-grw5s2pf	962	10	viral	viral	JJ
cord-256444-grw5s2pf	962	11	genomic	genomic	JJ
cord-256444-grw5s2pf	962	12	RNA	RNA	NNP
cord-256444-grw5s2pf	962	13	that	that	WDT
cord-256444-grw5s2pf	962	14	abolished	abolish	VBD
cord-256444-grw5s2pf	962	15	the	the	DT
cord-256444-grw5s2pf	962	16	binding	binding	NN
cord-256444-grw5s2pf	962	17	of	of	IN
cord-256444-grw5s2pf	962	18	cellular	cellular	JJ
cord-256444-grw5s2pf	962	19	proteins	protein	NNS
cord-256444-grw5s2pf	962	20	also	also	RB
cord-256444-grw5s2pf	962	21	inhibited	inhibit	VBD
cord-256444-grw5s2pf	962	22	both	both	DT
cord-256444-grw5s2pf	962	23	negative	negative	JJ
cord-256444-grw5s2pf	962	24	-	-	HYPH
cord-256444-grw5s2pf	962	25	strand	strand	NN
cord-256444-grw5s2pf	962	26	and	and	CC
cord-256444-grw5s2pf	962	27	positive	positive	JJ
cord-256444-grw5s2pf	962	28	-	-	HYPH
cord-256444-grw5s2pf	962	29	strand	strand	NN
cord-256444-grw5s2pf	962	30	RNA	RNA	NNP
cord-256444-grw5s2pf	962	31	synthesis	synthesis	NN
cord-256444-grw5s2pf	962	32	,	,	,
cord-256444-grw5s2pf	962	33	although	although	IN
cord-256444-grw5s2pf	962	34	the	the	DT
cord-256444-grw5s2pf	962	35	correlation	correlation	NN
cord-256444-grw5s2pf	962	36	between	between	IN
cord-256444-grw5s2pf	962	37	protein	protein	NN
cord-256444-grw5s2pf	962	38	binding	binding	NN
cord-256444-grw5s2pf	962	39	and	and	CC
cord-256444-grw5s2pf	962	40	RNA	RNA	NNP
cord-256444-grw5s2pf	962	41	replication	replication	NN
cord-256444-grw5s2pf	962	42	was	be	VBD
cord-256444-grw5s2pf	962	43	not	not	RB
cord-256444-grw5s2pf	962	44	absolute	absolute	JJ
cord-256444-grw5s2pf	962	45	(	(	-LRB-
cord-256444-grw5s2pf	962	46	Yu	Yu	NNP
cord-256444-grw5s2pf	962	47	and	and	CC
cord-256444-grw5s2pf	962	48	Leibowitz	Leibowitz	NNP
cord-256444-grw5s2pf	962	49	,	,	,
cord-256444-grw5s2pf	962	50	1995a	1995a	CD
cord-256444-grw5s2pf	962	51	)	)	-RRB-
cord-256444-grw5s2pf	962	52	.	.	.
cord-256444-grw5s2pf	963	1	Thus	thus	RB
cord-256444-grw5s2pf	963	2	,	,	,
cord-256444-grw5s2pf	963	3	cellular	cellular	JJ
cord-256444-grw5s2pf	963	4	proteins	protein	NNS
cord-256444-grw5s2pf	963	5	probably	probably	RB
cord-256444-grw5s2pf	963	6	play	play	VBP
cord-256444-grw5s2pf	963	7	a	a	DT
cord-256444-grw5s2pf	963	8	significant	significant	JJ
cord-256444-grw5s2pf	963	9	role	role	NN
cord-256444-grw5s2pf	963	10	in	in	IN
cord-256444-grw5s2pf	963	11	viral	viral	JJ
cord-256444-grw5s2pf	963	12	RNA	RNA	NNP
cord-256444-grw5s2pf	963	13	replication	replication	NN
cord-256444-grw5s2pf	963	14	and	and	CC
cord-256444-grw5s2pf	963	15	transcription	transcription	NN
cord-256444-grw5s2pf	963	16	.	.	.
cord-256444-grw5s2pf	964	1	Curiously	curiously	RB
cord-256444-grw5s2pf	964	2	,	,	,
cord-256444-grw5s2pf	964	3	viral	viral	JJ
cord-256444-grw5s2pf	964	4	proteins	protein	NNS
cord-256444-grw5s2pf	964	5	in	in	IN
cord-256444-grw5s2pf	964	6	the	the	DT
cord-256444-grw5s2pf	964	7	infected	infected	JJ
cord-256444-grw5s2pf	964	8	cell	cell	NN
cord-256444-grw5s2pf	964	9	extract	extract	NN
cord-256444-grw5s2pf	964	10	could	could	MD
cord-256444-grw5s2pf	964	11	not	not	RB
cord-256444-grw5s2pf	964	12	be	be	VB
cord-256444-grw5s2pf	964	13	cross	cros	VBN
cord-256444-grw5s2pf	964	14	-	-	VBN
cord-256444-grw5s2pf	964	15	linked	link	VBN
cord-256444-grw5s2pf	964	16	to	to	IN
cord-256444-grw5s2pf	964	17	the	the	DT
cord-256444-grw5s2pf	964	18	viral	viral	JJ
cord-256444-grw5s2pf	964	19	RNA	RNA	NNP
cord-256444-grw5s2pf	964	20	in	in	IN
cord-256444-grw5s2pf	964	21	vitro	vitro	FW
cord-256444-grw5s2pf	964	22	,	,	,
cord-256444-grw5s2pf	964	23	suggesting	suggest	VBG
cord-256444-grw5s2pf	964	24	that	that	IN
cord-256444-grw5s2pf	964	25	viral	viral	JJ
cord-256444-grw5s2pf	964	26	proteins	protein	NNS
cord-256444-grw5s2pf	964	27	may	may	MD
cord-256444-grw5s2pf	964	28	interact	interact	VB
cord-256444-grw5s2pf	964	29	with	with	IN
cord-256444-grw5s2pf	964	30	viral	viral	JJ
cord-256444-grw5s2pf	964	31	RNA	RNA	NNP
cord-256444-grw5s2pf	964	32	only	only	RB
cord-256444-grw5s2pf	964	33	indirectly	indirectly	RB
cord-256444-grw5s2pf	964	34	through	through	IN
cord-256444-grw5s2pf	964	35	cellular	cellular	JJ
cord-256444-grw5s2pf	964	36	proteins	protein	NNS
cord-256444-grw5s2pf	964	37	.	.	.
cord-256444-grw5s2pf	965	1	This	this	DT
cord-256444-grw5s2pf	965	2	is	be	VBZ
cord-256444-grw5s2pf	965	3	in	in	IN
cord-256444-grw5s2pf	965	4	contrast	contrast	NN
cord-256444-grw5s2pf	965	5	to	to	IN
cord-256444-grw5s2pf	965	6	the	the	DT
cord-256444-grw5s2pf	965	7	finding	finding	NN
cord-256444-grw5s2pf	965	8	that	that	IN
cord-256444-grw5s2pf	965	9	the	the	DT
cord-256444-grw5s2pf	965	10	purified	purify	VBN
cord-256444-grw5s2pf	965	11	N	n	NN
cord-256444-grw5s2pf	965	12	protein	protein	NN
cord-256444-grw5s2pf	965	13	can	can	MD
cord-256444-grw5s2pf	965	14	bind	bind	VB
cord-256444-grw5s2pf	965	15	to	to	IN
cord-256444-grw5s2pf	965	16	the	the	DT
cord-256444-grw5s2pf	965	17	leader	leader	NN
cord-256444-grw5s2pf	965	18	RNA	RNA	NNP
cord-256444-grw5s2pf	965	19	sequence	sequence	NN
cord-256444-grw5s2pf	965	20	in	in	IN
cord-256444-grw5s2pf	965	21	vitro	vitro	FW
cord-256444-grw5s2pf	966	1	Stohlman	Stohlman	NNP
cord-256444-grw5s2pf	966	2	et	et	NNP
cord-256444-grw5s2pf	966	3	al	al	NNP
cord-256444-grw5s2pf	966	4	.	.	NNP
cord-256444-grw5s2pf	966	5	,	,	,
cord-256444-grw5s2pf	966	6	1988	1988	CD
cord-256444-grw5s2pf	966	7	)	)	-RRB-
cord-256444-grw5s2pf	966	8	.	.	.
cord-256444-grw5s2pf	967	1	The	the	DT
cord-256444-grw5s2pf	967	2	reason	reason	NN
cord-256444-grw5s2pf	967	3	for	for	IN
cord-256444-grw5s2pf	967	4	this	this	DT
cord-256444-grw5s2pf	967	5	discrepancy	discrepancy	NN
cord-256444-grw5s2pf	967	6	is	be	VBZ
cord-256444-grw5s2pf	967	7	not	not	RB
cord-256444-grw5s2pf	967	8	clear	clear	JJ
cord-256444-grw5s2pf	967	9	.	.	.
cord-256444-grw5s2pf	968	1	The	the	DT
cord-256444-grw5s2pf	968	2	genomic	genomic	JJ
cord-256444-grw5s2pf	968	3	-	-	HYPH
cord-256444-grw5s2pf	968	4	sized	sized	JJ
cord-256444-grw5s2pf	968	5	RNA	RNA	NNP
cord-256444-grw5s2pf	968	6	in	in	IN
cord-256444-grw5s2pf	968	7	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	968	8	-	-	HYPH
cord-256444-grw5s2pf	968	9	infected	infect	VBN
cord-256444-grw5s2pf	968	10	cells	cell	NNS
cord-256444-grw5s2pf	968	11	theoretically	theoretically	RB
cord-256444-grw5s2pf	968	12	consists	consist	VBZ
cord-256444-grw5s2pf	968	13	of	of	IN
cord-256444-grw5s2pf	968	14	two	two	CD
cord-256444-grw5s2pf	968	15	populations	population	NNS
cord-256444-grw5s2pf	968	16	:	:	:
cord-256444-grw5s2pf	968	17	the	the	DT
cord-256444-grw5s2pf	968	18	messenger	messenger	NN
cord-256444-grw5s2pf	968	19	RNA	RNA	NNP
cord-256444-grw5s2pf	968	20	(	(	-LRB-
cord-256444-grw5s2pf	968	21	mRNA	mRNA	NNP
cord-256444-grw5s2pf	968	22	l	l	NNP
cord-256444-grw5s2pf	968	23	)	)	-RRB-
cord-256444-grw5s2pf	968	24	,	,	,
cord-256444-grw5s2pf	968	25	which	which	WDT
cord-256444-grw5s2pf	968	26	is	be	VBZ
cord-256444-grw5s2pf	968	27	translated	translate	VBN
cord-256444-grw5s2pf	968	28	to	to	TO
cord-256444-grw5s2pf	968	29	yield	yield	VB
cord-256444-grw5s2pf	968	30	gene	gene	NNP
cord-256444-grw5s2pf	968	31	l	l	NNP
cord-256444-grw5s2pf	968	32	a	a	NN
cord-256444-grw5s2pf	968	33	and	and	CC
cord-256444-grw5s2pf	968	34	l	l	NN
cord-256444-grw5s2pf	968	35	b	b	NNP
cord-256444-grw5s2pf	968	36	products	product	NNS
cord-256444-grw5s2pf	968	37	,	,	,
cord-256444-grw5s2pf	968	38	and	and	CC
cord-256444-grw5s2pf	968	39	the	the	DT
cord-256444-grw5s2pf	968	40	genomic	genomic	JJ
cord-256444-grw5s2pf	968	41	RNA	RNA	NNP
cord-256444-grw5s2pf	968	42	,	,	,
cord-256444-grw5s2pf	968	43	which	which	WDT
cord-256444-grw5s2pf	968	44	is	be	VBZ
cord-256444-grw5s2pf	968	45	destined	destine	VBN
cord-256444-grw5s2pf	968	46	to	to	TO
cord-256444-grw5s2pf	968	47	be	be	VB
cord-256444-grw5s2pf	968	48	packaged	package	VBN
cord-256444-grw5s2pf	968	49	into	into	IN
cord-256444-grw5s2pf	968	50	virion	virion	NN
cord-256444-grw5s2pf	968	51	.	.	.
cord-256444-grw5s2pf	969	1	Early	early	JJ
cord-256444-grw5s2pf	969	2	studies	study	NNS
cord-256444-grw5s2pf	969	3	demonstrated	demonstrate	VBD
cord-256444-grw5s2pf	969	4	that	that	IN
cord-256444-grw5s2pf	969	5	,	,	,
cord-256444-grw5s2pf	969	6	late	late	RB
cord-256444-grw5s2pf	969	7	in	in	IN
cord-256444-grw5s2pf	969	8	the	the	DT
cord-256444-grw5s2pf	969	9	infection	infection	NN
cord-256444-grw5s2pf	969	10	,	,	,
cord-256444-grw5s2pf	969	11	most	most	JJS
cord-256444-grw5s2pf	969	12	(	(	-LRB-
cord-256444-grw5s2pf	969	13	95	95	CD
cord-256444-grw5s2pf	969	14	%	%	NN
cord-256444-grw5s2pf	969	15	)	)	-RRB-
cord-256444-grw5s2pf	969	16	of	of	IN
cord-256444-grw5s2pf	969	17	the	the	DT
cord-256444-grw5s2pf	969	18	genomic	genomic	JJ
cord-256444-grw5s2pf	969	19	-	-	HYPH
cord-256444-grw5s2pf	969	20	sized	sized	JJ
cord-256444-grw5s2pf	969	21	RNA	RNA	NNP
cord-256444-grw5s2pf	969	22	in	in	IN
cord-256444-grw5s2pf	969	23	the	the	DT
cord-256444-grw5s2pf	969	24	cells	cell	NNS
cord-256444-grw5s2pf	969	25	was	be	VBD
cord-256444-grw5s2pf	969	26	associated	associate	VBN
cord-256444-grw5s2pf	969	27	with	with	IN
cord-256444-grw5s2pf	969	28	the	the	DT
cord-256444-grw5s2pf	969	29	viral	viral	JJ
cord-256444-grw5s2pf	969	30	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	969	31	,	,	,
cord-256444-grw5s2pf	969	32	while	while	IN
cord-256444-grw5s2pf	969	33	the	the	DT
cord-256444-grw5s2pf	969	34	remainder	remainder	NN
cord-256444-grw5s2pf	969	35	(	(	-LRB-
cord-256444-grw5s2pf	969	36	5	5	CD
cord-256444-grw5s2pf	969	37	%	%	NN
cord-256444-grw5s2pf	969	38	)	)	-RRB-
cord-256444-grw5s2pf	969	39	was	be	VBD
cord-256444-grw5s2pf	969	40	present	present	JJ
cord-256444-grw5s2pf	969	41	in	in	IN
cord-256444-grw5s2pf	969	42	polysomes	polysomes	NNP
cord-256444-grw5s2pf	970	1	Perlman	Perlman	NNP
cord-256444-grw5s2pf	970	2	et	et	NNP
cord-256444-grw5s2pf	970	3	al	al	NNP
cord-256444-grw5s2pf	970	4	.	.	NNP
cord-256444-grw5s2pf	970	5	,	,	,
cord-256444-grw5s2pf	970	6	1986	1986	CD
cord-256444-grw5s2pf	970	7	)	)	-RRB-
cord-256444-grw5s2pf	970	8	.	.	.
cord-256444-grw5s2pf	971	1	Presumably	presumably	RB
cord-256444-grw5s2pf	971	2	,	,	,
cord-256444-grw5s2pf	971	3	early	early	RB
cord-256444-grw5s2pf	971	4	in	in	IN
cord-256444-grw5s2pf	971	5	infection	infection	NN
cord-256444-grw5s2pf	971	6	,	,	,
cord-256444-grw5s2pf	971	7	most	most	JJS
cord-256444-grw5s2pf	971	8	of	of	IN
cord-256444-grw5s2pf	971	9	the	the	DT
cord-256444-grw5s2pf	971	10	genomic	genomic	NN
cord-256444-grw5s2pf	971	11	-	-	HYPH
cord-256444-grw5s2pf	971	12	sized	sized	JJ
cord-256444-grw5s2pf	971	13	RNA	RNA	NNP
cord-256444-grw5s2pf	971	14	would	would	MD
cord-256444-grw5s2pf	971	15	be	be	VB
cord-256444-grw5s2pf	971	16	associated	associate	VBN
cord-256444-grw5s2pf	971	17	with	with	IN
cord-256444-grw5s2pf	971	18	polysomes	polysome	NNS
cord-256444-grw5s2pf	971	19	to	to	TO
cord-256444-grw5s2pf	971	20	serve	serve	VB
cord-256444-grw5s2pf	971	21	as	as	IN
cord-256444-grw5s2pf	971	22	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	971	23	for	for	IN
cord-256444-grw5s2pf	971	24	the	the	DT
cord-256444-grw5s2pf	971	25	synthesis	synthesis	NN
cord-256444-grw5s2pf	971	26	of	of	IN
cord-256444-grw5s2pf	971	27	polymerase	polymerase	NN
cord-256444-grw5s2pf	971	28	;	;	:
cord-256444-grw5s2pf	971	29	however	however	RB
cord-256444-grw5s2pf	971	30	,	,	,
cord-256444-grw5s2pf	971	31	this	this	DT
cord-256444-grw5s2pf	971	32	has	have	VBZ
cord-256444-grw5s2pf	971	33	not	not	RB
cord-256444-grw5s2pf	971	34	been	be	VBN
cord-256444-grw5s2pf	971	35	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	971	36	.	.	.
cord-256444-grw5s2pf	972	1	It	-PRON-	PRP
cord-256444-grw5s2pf	972	2	is	be	VBZ
cord-256444-grw5s2pf	972	3	not	not	RB
cord-256444-grw5s2pf	972	4	clear	clear	JJ
cord-256444-grw5s2pf	972	5	whether	whether	IN
cord-256444-grw5s2pf	972	6	there	there	EX
cord-256444-grw5s2pf	972	7	is	be	VBZ
cord-256444-grw5s2pf	972	8	any	any	DT
cord-256444-grw5s2pf	972	9	difference	difference	NN
cord-256444-grw5s2pf	972	10	in	in	IN
cord-256444-grw5s2pf	972	11	structure	structure	NN
cord-256444-grw5s2pf	972	12	and	and	CC
cord-256444-grw5s2pf	972	13	mechanism	mechanism	NN
cord-256444-grw5s2pf	972	14	of	of	IN
cord-256444-grw5s2pf	972	15	synthesis	synthesis	NN
cord-256444-grw5s2pf	972	16	between	between	IN
cord-256444-grw5s2pf	972	17	these	these	DT
cord-256444-grw5s2pf	972	18	two	two	CD
cord-256444-grw5s2pf	972	19	RNA	RNA	NNP
cord-256444-grw5s2pf	972	20	populations	population	NNS
cord-256444-grw5s2pf	972	21	.	.	.
cord-256444-grw5s2pf	973	1	Since	since	IN
cord-256444-grw5s2pf	973	2	genomic	genomic	JJ
cord-256444-grw5s2pf	973	3	RNA	RNA	NNP
cord-256444-grw5s2pf	973	4	requires	require	VBZ
cord-256444-grw5s2pf	973	5	uninterrupted	uninterrupted	JJ
cord-256444-grw5s2pf	973	6	synthesis	synthesis	NN
cord-256444-grw5s2pf	973	7	from	from	IN
cord-256444-grw5s2pf	973	8	the	the	DT
cord-256444-grw5s2pf	973	9	fulllength	fulllength	NN
cord-256444-grw5s2pf	973	10	template	template	NN
cord-256444-grw5s2pf	973	11	,	,	,
cord-256444-grw5s2pf	973	12	whereas	whereas	IN
cord-256444-grw5s2pf	973	13	mRNAs	mrnas	PRP
cord-256444-grw5s2pf	973	14	involve	involve	VBP
cord-256444-grw5s2pf	973	15	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	973	16	transcription	transcription	NN
cord-256444-grw5s2pf	973	17	,	,	,
cord-256444-grw5s2pf	973	18	the	the	DT
cord-256444-grw5s2pf	973	19	two	two	CD
cord-256444-grw5s2pf	973	20	types	type	NNS
cord-256444-grw5s2pf	973	21	of	of	IN
cord-256444-grw5s2pf	973	22	genomic	genomic	JJ
cord-256444-grw5s2pf	973	23	-	-	HYPH
cord-256444-grw5s2pf	973	24	sized	sized	JJ
cord-256444-grw5s2pf	973	25	RNA	RNA	NNP
cord-256444-grw5s2pf	973	26	(	(	-LRB-
cord-256444-grw5s2pf	973	27	mRNA	mRNA	NNP
cord-256444-grw5s2pf	973	28	1	1	CD
cord-256444-grw5s2pf	973	29	and	and	CC
cord-256444-grw5s2pf	973	30	virion	virion	NN
cord-256444-grw5s2pf	973	31	genome	genome	NN
cord-256444-grw5s2pf	973	32	RNA	RNA	NNP
cord-256444-grw5s2pf	973	33	)	)	-RRB-
cord-256444-grw5s2pf	973	34	may	may	MD
cord-256444-grw5s2pf	973	35	be	be	VB
cord-256444-grw5s2pf	973	36	synthesized	synthesize	VBN
cord-256444-grw5s2pf	973	37	by	by	IN
cord-256444-grw5s2pf	973	38	two	two	CD
cord-256444-grw5s2pf	973	39	different	different	JJ
cord-256444-grw5s2pf	973	40	mechanisms	mechanism	NNS
cord-256444-grw5s2pf	973	41	.	.	.
cord-256444-grw5s2pf	974	1	A	a	DT
cord-256444-grw5s2pf	974	2	recent	recent	JJ
cord-256444-grw5s2pf	974	3	study	study	NN
cord-256444-grw5s2pf	974	4	suggests	suggest	VBZ
cord-256444-grw5s2pf	974	5	that	that	IN
cord-256444-grw5s2pf	974	6	at	at	IN
cord-256444-grw5s2pf	974	7	least	least	JJS
cord-256444-grw5s2pf	974	8	some	some	DT
cord-256444-grw5s2pf	974	9	of	of	IN
cord-256444-grw5s2pf	974	10	the	the	DT
cord-256444-grw5s2pf	974	11	MHV	MHV	NNP
cord-256444-grw5s2pf	974	12	genomic	genomic	JJ
cord-256444-grw5s2pf	974	13	-	-	HYPH
cord-256444-grw5s2pf	974	14	sized	sized	JJ
cord-256444-grw5s2pf	974	15	RNAs	rna	NNS
cord-256444-grw5s2pf	974	16	are	be	VBP
cord-256444-grw5s2pf	974	17	indeed	indeed	RB
cord-256444-grw5s2pf	974	18	synthesized	synthesize	VBN
cord-256444-grw5s2pf	974	19	by	by	IN
cord-256444-grw5s2pf	974	20	a	a	DT
cord-256444-grw5s2pf	974	21	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	974	22	transcription	transcription	NN
cord-256444-grw5s2pf	974	23	,	,	,
cord-256444-grw5s2pf	974	24	using	use	VBG
cord-256444-grw5s2pf	974	25	the	the	DT
cord-256444-grw5s2pf	974	26	U	u	NN
cord-256444-grw5s2pf	974	27	C	c	NN
cord-256444-grw5s2pf	974	28	U	u	NN
cord-256444-grw5s2pf	974	29	M	M	NNP
cord-256444-grw5s2pf	974	30	repeat	repeat	NN
cord-256444-grw5s2pf	974	31	in	in	IN
cord-256444-grw5s2pf	974	32	the	the	DT
cord-256444-grw5s2pf	974	33	leader	leader	NN
cord-256444-grw5s2pf	974	34	RNA	RNA	NNP
cord-256444-grw5s2pf	974	35	and	and	CC
cord-256444-grw5s2pf	974	36	the	the	DT
cord-256444-grw5s2pf	974	37	nine	nine	CD
cord-256444-grw5s2pf	974	38	-	-	HYPH
cord-256444-grw5s2pf	974	39	nucleotide	nucleotide	JJ
cord-256444-grw5s2pf	974	40	UUUAUAAAC	UUUAUAAAC	NNP
cord-256444-grw5s2pf	974	41	immediately	immediately	RB
cord-256444-grw5s2pf	974	42	downstream	downstream	RB
cord-256444-grw5s2pf	974	43	of	of	IN
cord-256444-grw5s2pf	974	44	the	the	DT
cord-256444-grw5s2pf	974	45	leader	leader	NN
cord-256444-grw5s2pf	974	46	RNA	RNA	NNP
cord-256444-grw5s2pf	974	47	as	as	IN
cord-256444-grw5s2pf	974	48	the	the	DT
cord-256444-grw5s2pf	974	49	transcription	transcription	NN
cord-256444-grw5s2pf	974	50	start	start	NN
cord-256444-grw5s2pf	974	51	site	site	NN
cord-256444-grw5s2pf	974	52	.	.	.
cord-256444-grw5s2pf	975	1	This	this	DT
cord-256444-grw5s2pf	975	2	raised	raise	VBD
cord-256444-grw5s2pf	975	3	the	the	DT
cord-256444-grw5s2pf	975	4	possibility	possibility	NN
cord-256444-grw5s2pf	975	5	that	that	IN
cord-256444-grw5s2pf	975	6	mRNA	mRNA	NNP
cord-256444-grw5s2pf	975	7	1	1	CD
cord-256444-grw5s2pf	975	8	and	and	CC
cord-256444-grw5s2pf	975	9	virion	virion	NN
cord-256444-grw5s2pf	975	10	genomic	genomic	JJ
cord-256444-grw5s2pf	975	11	RNA	RNA	NNP
cord-256444-grw5s2pf	975	12	are	be	VBP
cord-256444-grw5s2pf	975	13	distinguishable	distinguishable	JJ
cord-256444-grw5s2pf	975	14	.	.	.
cord-256444-grw5s2pf	976	1	However	however	RB
cord-256444-grw5s2pf	976	2	,	,	,
cord-256444-grw5s2pf	976	3	it	-PRON-	PRP
cord-256444-grw5s2pf	976	4	can	can	MD
cord-256444-grw5s2pf	976	5	not	not	RB
cord-256444-grw5s2pf	976	6	be	be	VB
cord-256444-grw5s2pf	976	7	inferred	infer	VBN
cord-256444-grw5s2pf	976	8	from	from	IN
cord-256444-grw5s2pf	976	9	this	this	DT
cord-256444-grw5s2pf	976	10	study	study	NN
cord-256444-grw5s2pf	976	11	that	that	IN
cord-256444-grw5s2pf	976	12	the	the	DT
cord-256444-grw5s2pf	976	13	fate	fate	NN
cord-256444-grw5s2pf	976	14	of	of	IN
cord-256444-grw5s2pf	976	15	the	the	DT
cord-256444-grw5s2pf	976	16	genomic	genomic	JJ
cord-256444-grw5s2pf	976	17	-	-	HYPH
cord-256444-grw5s2pf	976	18	sized	sized	JJ
cord-256444-grw5s2pf	976	19	RNA	RNA	NNP
cord-256444-grw5s2pf	976	20	products	product	NNS
cord-256444-grw5s2pf	976	21	derived	derive	VBN
cord-256444-grw5s2pf	976	22	from	from	IN
cord-256444-grw5s2pf	976	23	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	976	24	transcription	transcription	NN
cord-256444-grw5s2pf	976	25	is	be	VBZ
cord-256444-grw5s2pf	976	26	different	different	JJ
cord-256444-grw5s2pf	976	27	from	from	IN
cord-256444-grw5s2pf	976	28	the	the	DT
cord-256444-grw5s2pf	976	29	fate	fate	NN
cord-256444-grw5s2pf	976	30	of	of	IN
cord-256444-grw5s2pf	976	31	those	those	DT
cord-256444-grw5s2pf	976	32	derived	derive	VBN
cord-256444-grw5s2pf	976	33	from	from	IN
cord-256444-grw5s2pf	976	34	uninterrupted	uninterrupted	JJ
cord-256444-grw5s2pf	976	35	RNA	RNA	NNP
cord-256444-grw5s2pf	976	36	synthesis	synthesis	NN
cord-256444-grw5s2pf	976	37	.	.	.
cord-256444-grw5s2pf	977	1	The	the	DT
cord-256444-grw5s2pf	977	2	possible	possible	JJ
cord-256444-grw5s2pf	977	3	involvement	involvement	NN
cord-256444-grw5s2pf	977	4	of	of	IN
cord-256444-grw5s2pf	977	5	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	977	6	transcription	transcription	NN
cord-256444-grw5s2pf	977	7	in	in	IN
cord-256444-grw5s2pf	977	8	generating	generate	VBG
cord-256444-grw5s2pf	977	9	genomic	genomic	JJ
cord-256444-grw5s2pf	977	10	-	-	HYPH
cord-256444-grw5s2pf	977	11	sized	sized	JJ
cord-256444-grw5s2pf	977	12	RNA	RNA	NNP
cord-256444-grw5s2pf	977	13	may	may	MD
cord-256444-grw5s2pf	977	14	explain	explain	VB
cord-256444-grw5s2pf	977	15	several	several	JJ
cord-256444-grw5s2pf	977	16	interesting	interesting	JJ
cord-256444-grw5s2pf	977	17	findings	finding	NNS
cord-256444-grw5s2pf	977	18	regarding	regard	VBG
cord-256444-grw5s2pf	977	19	MHV	MHV	NNP
cord-256444-grw5s2pf	977	20	genomic	genomic	JJ
cord-256444-grw5s2pf	977	21	RNA	RNA	NNP
cord-256444-grw5s2pf	977	22	1	1	CD
cord-256444-grw5s2pf	977	23	.	.	.
cord-256444-grw5s2pf	978	1	The	the	DT
cord-256444-grw5s2pf	978	2	copy	copy	NN
cord-256444-grw5s2pf	978	3	number	number	NN
cord-256444-grw5s2pf	978	4	of	of	IN
cord-256444-grw5s2pf	978	5	the	the	DT
cord-256444-grw5s2pf	978	6	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	978	7	repeat	repeat	NN
cord-256444-grw5s2pf	978	8	in	in	IN
cord-256444-grw5s2pf	978	9	the	the	DT
cord-256444-grw5s2pf	978	10	leader	leader	NN
cord-256444-grw5s2pf	978	11	sequence	sequence	NN
cord-256444-grw5s2pf	978	12	of	of	IN
cord-256444-grw5s2pf	978	13	the	the	DT
cord-256444-grw5s2pf	978	14	genomic	genomic	JJ
cord-256444-grw5s2pf	978	15	RNA	RNA	NNP
cord-256444-grw5s2pf	978	16	,	,	,
cord-256444-grw5s2pf	978	17	which	which	WDT
cord-256444-grw5s2pf	978	18	ranges	range	VBZ
cord-256444-grw5s2pf	978	19	from	from	IN
cord-256444-grw5s2pf	978	20	two	two	CD
cord-256444-grw5s2pf	978	21	to	to	TO
cord-256444-grw5s2pf	978	22	four	four	CD
cord-256444-grw5s2pf	978	23	copies	copy	NNS
cord-256444-grw5s2pf	978	24	in	in	IN
cord-256444-grw5s2pf	978	25	different	different	JJ
cord-256444-grw5s2pf	978	26	MHV	MHV	NNP
cord-256444-grw5s2pf	978	27	strains	strain	NNS
cord-256444-grw5s2pf	978	28	,	,	,
cord-256444-grw5s2pf	978	29	rapidly	rapidly	RB
cord-256444-grw5s2pf	978	30	evolves	evolve	VBZ
cord-256444-grw5s2pf	978	31	during	during	IN
cord-256444-grw5s2pf	978	32	virus	virus	NN
cord-256444-grw5s2pf	978	33	passage	passage	NN
cord-256444-grw5s2pf	978	34	(	(	-LRB-
cord-256444-grw5s2pf	978	35	Makino	Makino	NNP
cord-256444-grw5s2pf	978	36	and	and	CC
cord-256444-grw5s2pf	978	37	Lai	Lai	NNP
cord-256444-grw5s2pf	978	38	,	,	,
cord-256444-grw5s2pf	978	39	1989a	1989a	CD
cord-256444-grw5s2pf	978	40	;	;	:
cord-256444-grw5s2pf	978	41	La	La	NNP
cord-256444-grw5s2pf	978	42	Monica	Monica	NNP
cord-256444-grw5s2pf	978	43	et	et	NNP
cord-256444-grw5s2pf	978	44	al	al	NNP
cord-256444-grw5s2pf	978	45	.	.	NNP
cord-256444-grw5s2pf	978	46	,	,	,
cord-256444-grw5s2pf	978	47	1992	1992	CD
cord-256444-grw5s2pf	978	48	)	)	-RRB-
cord-256444-grw5s2pf	978	49	.	.	.
cord-256444-grw5s2pf	979	1	Starting	start	VBG
cord-256444-grw5s2pf	979	2	with	with	IN
cord-256444-grw5s2pf	979	3	a	a	DT
cord-256444-grw5s2pf	979	4	pure	pure	JJ
cord-256444-grw5s2pf	979	5	virus	virus	NN
cord-256444-grw5s2pf	979	6	population	population	NN
cord-256444-grw5s2pf	979	7	,	,	,
cord-256444-grw5s2pf	979	8	the	the	DT
cord-256444-grw5s2pf	979	9	copy	copy	NN
cord-256444-grw5s2pf	979	10	number	number	NN
cord-256444-grw5s2pf	979	11	in	in	IN
cord-256444-grw5s2pf	979	12	the	the	DT
cord-256444-grw5s2pf	979	13	viral	viral	JJ
cord-256444-grw5s2pf	979	14	genomic	genomic	JJ
cord-256444-grw5s2pf	979	15	RNA	RNA	NNP
cord-256444-grw5s2pf	979	16	rapidly	rapidly	RB
cord-256444-grw5s2pf	979	17	becomes	become	VBZ
cord-256444-grw5s2pf	979	18	heterogeneous	heterogeneous	JJ
cord-256444-grw5s2pf	979	19	during	during	IN
cord-256444-grw5s2pf	979	20	serial	serial	JJ
cord-256444-grw5s2pf	979	21	passages	passage	NNS
cord-256444-grw5s2pf	979	22	in	in	IN
cord-256444-grw5s2pf	979	23	tissue	tissue	NN
cord-256444-grw5s2pf	979	24	culture	culture	NN
cord-256444-grw5s2pf	979	25	,	,	,
cord-256444-grw5s2pf	979	26	and	and	CC
cord-256444-grw5s2pf	979	27	a	a	DT
cord-256444-grw5s2pf	979	28	new	new	JJ
cord-256444-grw5s2pf	979	29	virus	virus	NN
cord-256444-grw5s2pf	979	30	population	population	NN
cord-256444-grw5s2pf	979	31	with	with	IN
cord-256444-grw5s2pf	979	32	a	a	DT
cord-256444-grw5s2pf	979	33	different	different	JJ
cord-256444-grw5s2pf	979	34	copy	copy	NN
cord-256444-grw5s2pf	979	35	number	number	NN
cord-256444-grw5s2pf	979	36	of	of	IN
cord-256444-grw5s2pf	979	37	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	979	38	repeats	repeat	VBZ
cord-256444-grw5s2pf	979	39	emerges	emerge	VBZ
cord-256444-grw5s2pf	979	40	(	(	-LRB-
cord-256444-grw5s2pf	979	41	Makino	Makino	NNP
cord-256444-grw5s2pf	979	42	and	and	CC
cord-256444-grw5s2pf	979	43	Lai	Lai	NNP
cord-256444-grw5s2pf	979	44	,	,	,
cord-256444-grw5s2pf	979	45	1989a	1989a	CD
cord-256444-grw5s2pf	979	46	)	)	-RRB-
cord-256444-grw5s2pf	979	47	.	.	.
cord-256444-grw5s2pf	980	1	Since	since	IN
cord-256444-grw5s2pf	980	2	this	this	DT
cord-256444-grw5s2pf	980	3	sequence	sequence	NN
cord-256444-grw5s2pf	980	4	variation	variation	NN
cord-256444-grw5s2pf	980	5	is	be	VBZ
cord-256444-grw5s2pf	980	6	seen	see	VBN
cord-256444-grw5s2pf	980	7	in	in	IN
cord-256444-grw5s2pf	980	8	the	the	DT
cord-256444-grw5s2pf	980	9	leader	leader	NN
cord-256444-grw5s2pf	980	10	region	region	NN
cord-256444-grw5s2pf	980	11	but	but	CC
cord-256444-grw5s2pf	980	12	not	not	RB
cord-256444-grw5s2pf	980	13	in	in	IN
cord-256444-grw5s2pf	980	14	the	the	DT
cord-256444-grw5s2pf	980	15	IG	IG	NNP
cord-256444-grw5s2pf	980	16	regions	region	NNS
cord-256444-grw5s2pf	980	17	,	,	,
cord-256444-grw5s2pf	980	18	where	where	WRB
cord-256444-grw5s2pf	980	19	uninterrupted	uninterrupted	JJ
cord-256444-grw5s2pf	980	20	RNA	RNA	NNP
cord-256444-grw5s2pf	980	21	synthesis	synthesis	NN
cord-256444-grw5s2pf	980	22	probably	probably	RB
cord-256444-grw5s2pf	980	23	occurs	occur	VBZ
cord-256444-grw5s2pf	980	24	,	,	,
cord-256444-grw5s2pf	980	25	this	this	DT
cord-256444-grw5s2pf	980	26	finding	finding	NN
cord-256444-grw5s2pf	980	27	is	be	VBZ
cord-256444-grw5s2pf	980	28	best	well	RBS
cord-256444-grw5s2pf	980	29	explained	explain	VBN
cord-256444-grw5s2pf	980	30	by	by	IN
cord-256444-grw5s2pf	980	31	the	the	DT
cord-256444-grw5s2pf	980	32	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	980	33	transcription	transcription	NN
cord-256444-grw5s2pf	980	34	mechanism	mechanism	NN
cord-256444-grw5s2pf	980	35	involving	involve	VBG
cord-256444-grw5s2pf	980	36	the	the	DT
cord-256444-grw5s2pf	980	37	5	5	CD
cord-256444-grw5s2pf	980	38	'	'	POS
cord-256444-grw5s2pf	980	39	leader	leader	NN
cord-256444-grw5s2pf	980	40	region	region	NN
cord-256444-grw5s2pf	980	41	.	.	.
cord-256444-grw5s2pf	981	1	The	the	DT
cord-256444-grw5s2pf	981	2	imprecise	imprecise	JJ
cord-256444-grw5s2pf	981	3	fusion	fusion	NN
cord-256444-grw5s2pf	981	4	of	of	IN
cord-256444-grw5s2pf	981	5	the	the	DT
cord-256444-grw5s2pf	981	6	leader	leader	NN
cord-256444-grw5s2pf	981	7	RNA	RNA	NNP
cord-256444-grw5s2pf	981	8	to	to	IN
cord-256444-grw5s2pf	981	9	the	the	DT
cord-256444-grw5s2pf	981	10	mRNA	mRNA	NNP
cord-256444-grw5s2pf	981	11	start	start	NN
cord-256444-grw5s2pf	981	12	sites	site	NNS
cord-256444-grw5s2pf	981	13	would	would	MD
cord-256444-grw5s2pf	981	14	result	result	VB
cord-256444-grw5s2pf	981	15	in	in	IN
cord-256444-grw5s2pf	981	16	heterogeneity	heterogeneity	NN
cord-256444-grw5s2pf	981	17	of	of	IN
cord-256444-grw5s2pf	981	18	the	the	DT
cord-256444-grw5s2pf	981	19	copy	copy	JJ
cord-256444-grw5s2pf	981	20	number	number	NN
cord-256444-grw5s2pf	981	21	of	of	IN
cord-256444-grw5s2pf	981	22	the	the	DT
cord-256444-grw5s2pf	981	23	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	981	24	repeats	repeat	VBZ
cord-256444-grw5s2pf	981	25	Lai	Lai	NNP
cord-256444-grw5s2pf	981	26	,	,	,
cord-256444-grw5s2pf	981	27	1990	1990	CD
cord-256444-grw5s2pf	981	28	)	)	-RRB-
cord-256444-grw5s2pf	981	29	.	.	.
cord-256444-grw5s2pf	982	1	Such	such	JJ
cord-256444-grw5s2pf	982	2	heterogeneity	heterogeneity	NN
cord-256444-grw5s2pf	982	3	is	be	VBZ
cord-256444-grw5s2pf	982	4	not	not	RB
cord-256444-grw5s2pf	982	5	observed	observe	VBN
cord-256444-grw5s2pf	982	6	when	when	WRB
cord-256444-grw5s2pf	982	7	the	the	DT
cord-256444-grw5s2pf	982	8	virus	virus	NN
cord-256444-grw5s2pf	982	9	,	,	,
cord-256444-grw5s2pf	982	10	e.g.	e.g.	RB
cord-256444-grw5s2pf	982	11	,	,	,
cord-256444-grw5s2pf	982	12	BCV	BCV	NNP
cord-256444-grw5s2pf	982	13	,	,	,
cord-256444-grw5s2pf	982	14	contains	contain	VBZ
cord-256444-grw5s2pf	982	15	only	only	RB
cord-256444-grw5s2pf	982	16	one	one	CD
cord-256444-grw5s2pf	982	17	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	982	18	copy	copy	NN
cord-256444-grw5s2pf	982	19	in	in	IN
cord-256444-grw5s2pf	982	20	the	the	DT
cord-256444-grw5s2pf	982	21	leader	leader	NN
cord-256444-grw5s2pf	982	22	RNA	RNA	NNP
cord-256444-grw5s2pf	982	23	(	(	-LRB-
cord-256444-grw5s2pf	982	24	Hofmann	Hofmann	NNP
cord-256444-grw5s2pf	982	25	et	et	NNP
cord-256444-grw5s2pf	982	26	al	al	NNP
cord-256444-grw5s2pf	982	27	.	.	NNP
cord-256444-grw5s2pf	982	28	,	,	,
cord-256444-grw5s2pf	982	29	1993a	1993a	CD
cord-256444-grw5s2pf	982	30	)	)	-RRB-
cord-256444-grw5s2pf	982	31	.	.	.
cord-256444-grw5s2pf	983	1	The	the	DT
cord-256444-grw5s2pf	983	2	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	983	3	region	region	NN
cord-256444-grw5s2pf	983	4	at	at	IN
cord-256444-grw5s2pf	983	5	the	the	DT
cord-256444-grw5s2pf	983	6	5	5	CD
cord-256444-grw5s2pf	983	7	'	'	NN
cord-256444-grw5s2pf	983	8	end	end	NN
cord-256444-grw5s2pf	983	9	of	of	IN
cord-256444-grw5s2pf	983	10	the	the	DT
cord-256444-grw5s2pf	983	11	genomic	genomic	JJ
cord-256444-grw5s2pf	983	12	RNA	RNA	NNP
cord-256444-grw5s2pf	983	13	is	be	VBZ
cord-256444-grw5s2pf	983	14	a	a	DT
cord-256444-grw5s2pf	983	15	hot	hot	JJ
cord-256444-grw5s2pf	983	16	spot	spot	NN
cord-256444-grw5s2pf	983	17	of	of	IN
cord-256444-grw5s2pf	983	18	RNA	RNA	NNP
cord-256444-grw5s2pf	983	19	recombination	recombination	NN
cord-256444-grw5s2pf	983	20	during	during	IN
cord-256444-grw5s2pf	983	21	mixed	mixed	JJ
cord-256444-grw5s2pf	983	22	infection	infection	NN
cord-256444-grw5s2pf	983	23	of	of	IN
cord-256444-grw5s2pf	983	24	MHVs	MHVs	NNP
cord-256444-grw5s2pf	983	25	,	,	,
cord-256444-grw5s2pf	983	26	resulting	result	VBG
cord-256444-grw5s2pf	983	27	in	in	IN
cord-256444-grw5s2pf	983	28	recombinant	recombinant	JJ
cord-256444-grw5s2pf	983	29	MHVs	MHVs	NNP
cord-256444-grw5s2pf	983	30	with	with	IN
cord-256444-grw5s2pf	983	31	a	a	DT
cord-256444-grw5s2pf	983	32	crossover	crossover	NN
cord-256444-grw5s2pf	983	33	site	site	NN
cord-256444-grw5s2pf	983	34	at	at	IN
cord-256444-grw5s2pf	983	35	the	the	DT
cord-256444-grw5s2pf	983	36	3	3	CD
cord-256444-grw5s2pf	983	37	'	'	NN
cord-256444-grw5s2pf	983	38	end	end	NN
cord-256444-grw5s2pf	983	39	of	of	IN
cord-256444-grw5s2pf	983	40	the	the	DT
cord-256444-grw5s2pf	983	41	leader	leader	NN
cord-256444-grw5s2pf	983	42	RNA	RNA	NNP
cord-256444-grw5s2pf	983	43	sequence	sequence	NN
cord-256444-grw5s2pf	983	44	.	.	.
cord-256444-grw5s2pf	984	1	This	this	DT
cord-256444-grw5s2pf	984	2	result	result	NN
cord-256444-grw5s2pf	984	3	is	be	VBZ
cord-256444-grw5s2pf	984	4	best	well	RBS
cord-256444-grw5s2pf	984	5	explained	explain	VBN
cord-256444-grw5s2pf	984	6	by	by	IN
cord-256444-grw5s2pf	984	7	the	the	DT
cord-256444-grw5s2pf	984	8	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	984	9	RNA	RNA	NNP
cord-256444-grw5s2pf	984	10	synthesis	synthesis	NN
cord-256444-grw5s2pf	984	11	at	at	IN
cord-256444-grw5s2pf	984	12	the	the	DT
cord-256444-grw5s2pf	984	13	5	5	CD
cord-256444-grw5s2pf	984	14	'	'	NN
cord-256444-grw5s2pf	984	15	end	end	NN
cord-256444-grw5s2pf	984	16	of	of	IN
cord-256444-grw5s2pf	984	17	the	the	DT
cord-256444-grw5s2pf	984	18	genomic	genomic	JJ
cord-256444-grw5s2pf	984	19	RNA	rna	NN
cord-256444-grw5s2pf	984	20	.	.	.
cord-256444-grw5s2pf	985	1	3	3	LS
cord-256444-grw5s2pf	985	2	.	.	.
cord-256444-grw5s2pf	986	1	If	if	IN
cord-256444-grw5s2pf	986	2	the	the	DT
cord-256444-grw5s2pf	986	3	generation	generation	NN
cord-256444-grw5s2pf	986	4	of	of	IN
cord-256444-grw5s2pf	986	5	DI	DI	NNP
cord-256444-grw5s2pf	986	6	RNAs	rna	NNS
cord-256444-grw5s2pf	986	7	is	be	VBZ
cord-256444-grw5s2pf	986	8	viewed	view	VBN
cord-256444-grw5s2pf	986	9	as	as	IN
cord-256444-grw5s2pf	986	10	an	an	DT
cord-256444-grw5s2pf	986	11	anomaly	anomaly	NN
cord-256444-grw5s2pf	986	12	of	of	IN
cord-256444-grw5s2pf	986	13	RNA	RNA	NNP
cord-256444-grw5s2pf	986	14	replication	replication	NN
cord-256444-grw5s2pf	986	15	,	,	,
cord-256444-grw5s2pf	986	16	the	the	DT
cord-256444-grw5s2pf	986	17	structure	structure	NN
cord-256444-grw5s2pf	986	18	of	of	IN
cord-256444-grw5s2pf	986	19	naturally	naturally	RB
cord-256444-grw5s2pf	986	20	occurring	occur	VBG
cord-256444-grw5s2pf	986	21	DI	DI	NNP
cord-256444-grw5s2pf	986	22	RNAs	rna	NNS
cord-256444-grw5s2pf	986	23	reveals	reveal	VBZ
cord-256444-grw5s2pf	986	24	an	an	DT
cord-256444-grw5s2pf	986	25	insight	insight	NN
cord-256444-grw5s2pf	986	26	into	into	IN
cord-256444-grw5s2pf	986	27	the	the	DT
cord-256444-grw5s2pf	986	28	mechanism	mechanism	NN
cord-256444-grw5s2pf	986	29	of	of	IN
cord-256444-grw5s2pf	986	30	RNA	RNA	NNP
cord-256444-grw5s2pf	986	31	replication	replication	NN
cord-256444-grw5s2pf	986	32	.	.	.
cord-256444-grw5s2pf	987	1	Most	Most	JJS
cord-256444-grw5s2pf	987	2	of	of	IN
cord-256444-grw5s2pf	987	3	the	the	DT
cord-256444-grw5s2pf	987	4	naturally	naturally	RB
cord-256444-grw5s2pf	987	5	occurring	occur	VBG
cord-256444-grw5s2pf	987	6	MHV	MHV	NNP
cord-256444-grw5s2pf	987	7	DI	DI	NNP
cord-256444-grw5s2pf	987	8	RNAs	rna	NNS
cord-256444-grw5s2pf	987	9	have	have	VBP
cord-256444-grw5s2pf	987	10	a	a	DT
cord-256444-grw5s2pf	987	11	copy	copy	NN
cord-256444-grw5s2pf	987	12	number	number	NN
cord-256444-grw5s2pf	987	13	of	of	IN
cord-256444-grw5s2pf	987	14	the	the	DT
cord-256444-grw5s2pf	987	15	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	987	16	repeat	repeat	NN
cord-256444-grw5s2pf	987	17	different	different	JJ
cord-256444-grw5s2pf	987	18	from	from	IN
cord-256444-grw5s2pf	987	19	that	that	DT
cord-256444-grw5s2pf	987	20	of	of	IN
cord-256444-grw5s2pf	987	21	the	the	DT
cord-256444-grw5s2pf	987	22	parental	parental	JJ
cord-256444-grw5s2pf	987	23	virus	virus	NN
cord-256444-grw5s2pf	987	24	,	,	,
cord-256444-grw5s2pf	987	25	and	and	CC
cord-256444-grw5s2pf	987	26	most	most	JJS
cord-256444-grw5s2pf	987	27	lack	lack	VBP
cord-256444-grw5s2pf	987	28	a	a	DT
cord-256444-grw5s2pf	987	29	ninenucleotide	ninenucleotide	JJ
cord-256444-grw5s2pf	987	30	sequence	sequence	NN
cord-256444-grw5s2pf	987	31	downstream	downstream	RB
cord-256444-grw5s2pf	987	32	of	of	IN
cord-256444-grw5s2pf	987	33	the	the	DT
cord-256444-grw5s2pf	987	34	UCUAA	UCUAA	NNP
cord-256444-grw5s2pf	987	35	repeats	repeat	VBZ
cord-256444-grw5s2pf	987	36	.	.	.
cord-256444-grw5s2pf	988	1	As	as	IN
cord-256444-grw5s2pf	988	2	discussed	discuss	VBN
cord-256444-grw5s2pf	988	3	above	above	RB
cord-256444-grw5s2pf	988	4	,	,	,
cord-256444-grw5s2pf	988	5	this	this	DT
cord-256444-grw5s2pf	988	6	is	be	VBZ
cord-256444-grw5s2pf	988	7	a	a	DT
cord-256444-grw5s2pf	988	8	reflection	reflection	NN
cord-256444-grw5s2pf	988	9	of	of	IN
cord-256444-grw5s2pf	988	10	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	988	11	transcription	transcription	NN
cord-256444-grw5s2pf	988	12	in	in	IN
cord-256444-grw5s2pf	988	13	the	the	DT
cord-256444-grw5s2pf	988	14	region	region	NN
cord-256444-grw5s2pf	988	15	.	.	.
cord-256444-grw5s2pf	989	1	The	the	DT
cord-256444-grw5s2pf	989	2	understanding	understanding	NN
cord-256444-grw5s2pf	989	3	of	of	IN
cord-256444-grw5s2pf	989	4	the	the	DT
cord-256444-grw5s2pf	989	5	mechanism	mechanism	NN
cord-256444-grw5s2pf	989	6	of	of	IN
cord-256444-grw5s2pf	989	7	RNA	RNA	NNP
cord-256444-grw5s2pf	989	8	replication	replication	NN
cord-256444-grw5s2pf	989	9	has	have	VBZ
cord-256444-grw5s2pf	989	10	been	be	VBN
cord-256444-grw5s2pf	989	11	aided	aid	VBN
cord-256444-grw5s2pf	989	12	by	by	IN
cord-256444-grw5s2pf	989	13	the	the	DT
cord-256444-grw5s2pf	989	14	use	use	NN
cord-256444-grw5s2pf	989	15	of	of	IN
cord-256444-grw5s2pf	989	16	in	in	IN
cord-256444-grw5s2pf	989	17	uitro	uitro	NNP
cord-256444-grw5s2pf	989	18	-	-	HYPH
cord-256444-grw5s2pf	989	19	transcribed	transcribe	VBN
cord-256444-grw5s2pf	989	20	DI	DI	NNP
cord-256444-grw5s2pf	989	21	RNA	RNA	NNP
cord-256444-grw5s2pf	989	22	generated	generate	VBN
cord-256444-grw5s2pf	989	23	from	from	IN
cord-256444-grw5s2pf	989	24	cloned	clone	VBN
cord-256444-grw5s2pf	989	25	cDNA	cdna	NN
cord-256444-grw5s2pf	989	26	.	.	.
cord-256444-grw5s2pf	990	1	When	when	WRB
cord-256444-grw5s2pf	990	2	DI	DI	NNP
cord-256444-grw5s2pf	990	3	RNA	RNA	NNP
cord-256444-grw5s2pf	990	4	was	be	VBD
cord-256444-grw5s2pf	990	5	transfected	transfecte	VBN
cord-256444-grw5s2pf	990	6	into	into	IN
cord-256444-grw5s2pf	990	7	virus	virus	NN
cord-256444-grw5s2pf	990	8	-	-	HYPH
cord-256444-grw5s2pf	990	9	infected	infect	VBN
cord-256444-grw5s2pf	990	10	cells	cell	NNS
cord-256444-grw5s2pf	990	11	,	,	,
cord-256444-grw5s2pf	990	12	the	the	DT
cord-256444-grw5s2pf	990	13	leader	leader	NN
cord-256444-grw5s2pf	990	14	RNA	RNA	NNP
cord-256444-grw5s2pf	990	15	was	be	VBD
cord-256444-grw5s2pf	990	16	rapidly	rapidly	RB
cord-256444-grw5s2pf	990	17	replaced	replace	VBN
cord-256444-grw5s2pf	990	18	by	by	IN
cord-256444-grw5s2pf	990	19	that	that	DT
cord-256444-grw5s2pf	990	20	of	of	IN
cord-256444-grw5s2pf	990	21	the	the	DT
cord-256444-grw5s2pf	990	22	helper	helper	NN
cord-256444-grw5s2pf	990	23	virus	virus	NN
cord-256444-grw5s2pf	990	24	(	(	-LRB-
cord-256444-grw5s2pf	990	25	Makino	Makino	NNP
cord-256444-grw5s2pf	990	26	and	and	CC
cord-256444-grw5s2pf	990	27	Lai	Lai	NNP
cord-256444-grw5s2pf	990	28	,	,	,
cord-256444-grw5s2pf	990	29	1989b	1989b	CD
cord-256444-grw5s2pf	990	30	;	;	:
cord-256444-grw5s2pf	990	31	.	.	.
cord-256444-grw5s2pf	991	1	This	this	DT
cord-256444-grw5s2pf	991	2	leader	leader	NN
cord-256444-grw5s2pf	991	3	exchange	exchange	NN
cord-256444-grw5s2pf	991	4	is	be	VBZ
cord-256444-grw5s2pf	991	5	dependent	dependent	JJ
cord-256444-grw5s2pf	991	6	on	on	IN
cord-256444-grw5s2pf	991	7	the	the	DT
cord-256444-grw5s2pf	991	8	presence	presence	NN
cord-256444-grw5s2pf	991	9	of	of	IN
cord-256444-grw5s2pf	991	10	the	the	DT
cord-256444-grw5s2pf	991	11	nine	nine	CD
cord-256444-grw5s2pf	991	12	-	-	HYPH
cord-256444-grw5s2pf	991	13	nucleotide	nucleotide	JJ
cord-256444-grw5s2pf	991	14	sequence	sequence	NN
cord-256444-grw5s2pf	991	15	(	(	-LRB-
cord-256444-grw5s2pf	991	16	UUUAUAAAC	UUUAUAAAC	NNP
cord-256444-grw5s2pf	991	17	)	)	-RRB-
cord-256444-grw5s2pf	991	18	in	in	IN
cord-256444-grw5s2pf	991	19	the	the	DT
cord-256444-grw5s2pf	991	20	DI	DI	NNP
cord-256444-grw5s2pf	991	21	RNA	RNA	NNP
cord-256444-grw5s2pf	991	22	(	(	-LRB-
cord-256444-grw5s2pf	991	23	Makino	Makino	NNP
cord-256444-grw5s2pf	991	24	and	and	CC
cord-256444-grw5s2pf	991	25	Lai	Lai	NNP
cord-256444-grw5s2pf	991	26	,	,	,
cord-256444-grw5s2pf	991	27	1989b	1989b	CD
cord-256444-grw5s2pf	991	28	)	)	-RRB-
cord-256444-grw5s2pf	991	29	,	,	,
cord-256444-grw5s2pf	991	30	consistent	consistent	JJ
cord-256444-grw5s2pf	991	31	with	with	IN
cord-256444-grw5s2pf	991	32	the	the	DT
cord-256444-grw5s2pf	991	33	finding	finding	NN
cord-256444-grw5s2pf	991	34	that	that	IN
cord-256444-grw5s2pf	991	35	this	this	DT
cord-256444-grw5s2pf	991	36	sequence	sequence	NN
cord-256444-grw5s2pf	991	37	serves	serve	VBZ
cord-256444-grw5s2pf	991	38	as	as	IN
cord-256444-grw5s2pf	991	39	an	an	DT
cord-256444-grw5s2pf	991	40	mRNA	mrna	NN
cord-256444-grw5s2pf	991	41	start	start	NN
cord-256444-grw5s2pf	991	42	signal	signal	JJ
cord-256444-grw5s2pf	991	43	for	for	IN
cord-256444-grw5s2pf	991	44	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	991	45	transcription	transcription	NN
cord-256444-grw5s2pf	991	46	.	.	.
cord-256444-grw5s2pf	992	1	The	the	DT
cord-256444-grw5s2pf	992	2	use	use	NN
cord-256444-grw5s2pf	992	3	of	of	IN
cord-256444-grw5s2pf	992	4	the	the	DT
cord-256444-grw5s2pf	992	5	cloned	clone	VBN
cord-256444-grw5s2pf	992	6	DI	DI	NNP
cord-256444-grw5s2pf	992	7	RNA	RNA	NNP
cord-256444-grw5s2pf	992	8	also	also	RB
cord-256444-grw5s2pf	992	9	allowed	allow	VBD
cord-256444-grw5s2pf	992	10	the	the	DT
cord-256444-grw5s2pf	992	11	determination	determination	NN
cord-256444-grw5s2pf	992	12	of	of	IN
cord-256444-grw5s2pf	992	13	the	the	DT
cord-256444-grw5s2pf	992	14	cis	cis	NNP
cord-256444-grw5s2pf	992	15	-	-	HYPH
cord-256444-grw5s2pf	992	16	acting	act	VBG
cord-256444-grw5s2pf	992	17	signals	signal	NNS
cord-256444-grw5s2pf	992	18	for	for	IN
cord-256444-grw5s2pf	992	19	RNA	rna	NN
cord-256444-grw5s2pf	992	20	replication	replication	NN
cord-256444-grw5s2pf	992	21	(	(	-LRB-
cord-256444-grw5s2pf	992	22	Kim	Kim	NNP
cord-256444-grw5s2pf	992	23	et	et	NNP
cord-256444-grw5s2pf	992	24	al	al	NNP
cord-256444-grw5s2pf	992	25	.	.	NNP
cord-256444-grw5s2pf	992	26	,	,	,
cord-256444-grw5s2pf	992	27	199313	199313	CD
cord-256444-grw5s2pf	992	28	;	;	:
cord-256444-grw5s2pf	992	29	Lin	Lin	NNP
cord-256444-grw5s2pf	992	30	and	and	CC
cord-256444-grw5s2pf	992	31	Lai	Lai	NNP
cord-256444-grw5s2pf	992	32	,	,	,
cord-256444-grw5s2pf	992	33	1993	1993	CD
cord-256444-grw5s2pf	992	34	)	)	-RRB-
cord-256444-grw5s2pf	992	35	.	.	.
cord-256444-grw5s2pf	993	1	It	-PRON-	PRP
cord-256444-grw5s2pf	993	2	was	be	VBD
cord-256444-grw5s2pf	993	3	shown	show	VBN
cord-256444-grw5s2pf	993	4	that	that	IN
cord-256444-grw5s2pf	993	5	more	more	JJR
cord-256444-grw5s2pf	993	6	than	than	IN
cord-256444-grw5s2pf	993	7	400	400	CD
cord-256444-grw5s2pf	993	8	nucleotides	nucleotide	NNS
cord-256444-grw5s2pf	993	9	at	at	IN
cord-256444-grw5s2pf	993	10	both	both	CC
cord-256444-grw5s2pf	993	11	the	the	DT
cord-256444-grw5s2pf	993	12	5	5	CD
cord-256444-grw5s2pf	993	13	'	'	''
cord-256444-grw5s2pf	993	14	and	and	CC
cord-256444-grw5s2pf	993	15	3	3	CD
cord-256444-grw5s2pf	993	16	'	'	POS
cord-256444-grw5s2pf	993	17	ends	end	NNS
cord-256444-grw5s2pf	993	18	of	of	IN
cord-256444-grw5s2pf	993	19	the	the	DT
cord-256444-grw5s2pf	993	20	DI	DI	NNP
cord-256444-grw5s2pf	993	21	RNA	RNA	NNP
cord-256444-grw5s2pf	993	22	are	be	VBP
cord-256444-grw5s2pf	993	23	required	require	VBN
cord-256444-grw5s2pf	993	24	for	for	IN
cord-256444-grw5s2pf	993	25	RNA	RNA	NNP
cord-256444-grw5s2pf	993	26	replication	replication	NN
cord-256444-grw5s2pf	993	27	,	,	,
cord-256444-grw5s2pf	993	28	and	and	CC
cord-256444-grw5s2pf	993	29	that	that	IN
cord-256444-grw5s2pf	993	30	some	some	DT
cord-256444-grw5s2pf	993	31	MHV	MHV	NNP
cord-256444-grw5s2pf	993	32	DI	DI	NNP
cord-256444-grw5s2pf	993	33	RNAs	rna	NNS
cord-256444-grw5s2pf	993	34	also	also	RB
cord-256444-grw5s2pf	993	35	required	require	VBD
cord-256444-grw5s2pf	993	36	a	a	DT
cord-256444-grw5s2pf	993	37	stretch	stretch	NN
cord-256444-grw5s2pf	993	38	(	(	-LRB-
cord-256444-grw5s2pf	993	39	130	130	CD
cord-256444-grw5s2pf	993	40	nt	nt	NN
cord-256444-grw5s2pf	993	41	)	)	-RRB-
cord-256444-grw5s2pf	993	42	of	of	IN
cord-256444-grw5s2pf	993	43	internal	internal	JJ
cord-256444-grw5s2pf	993	44	sequence	sequence	NN
cord-256444-grw5s2pf	993	45	in	in	IN
cord-256444-grw5s2pf	993	46	the	the	DT
cord-256444-grw5s2pf	993	47	gene	gene	NN
cord-256444-grw5s2pf	993	48	1	1	CD
cord-256444-grw5s2pf	993	49	region	region	NN
cord-256444-grw5s2pf	993	50	for	for	IN
cord-256444-grw5s2pf	993	51	RNA	RNA	NNP
cord-256444-grw5s2pf	993	52	replication	replication	NN
cord-256444-grw5s2pf	993	53	;	;	:
cord-256444-grw5s2pf	993	54	however	however	RB
cord-256444-grw5s2pf	993	55	,	,	,
cord-256444-grw5s2pf	993	56	the	the	DT
cord-256444-grw5s2pf	993	57	requirement	requirement	NN
cord-256444-grw5s2pf	993	58	for	for	IN
cord-256444-grw5s2pf	993	59	the	the	DT
cord-256444-grw5s2pf	993	60	internal	internal	JJ
cord-256444-grw5s2pf	993	61	sequence	sequence	NN
cord-256444-grw5s2pf	993	62	was	be	VBD
cord-256444-grw5s2pf	993	63	not	not	RB
cord-256444-grw5s2pf	993	64	observed	observe	VBN
cord-256444-grw5s2pf	993	65	in	in	IN
cord-256444-grw5s2pf	993	66	other	other	JJ
cord-256444-grw5s2pf	993	67	MHV	MHV	NNP
cord-256444-grw5s2pf	993	68	or	or	CC
cord-256444-grw5s2pf	993	69	BCV	BCV	NNP
cord-256444-grw5s2pf	993	70	DI	DI	NNP
cord-256444-grw5s2pf	993	71	RNA	RNA	NNP
cord-256444-grw5s2pf	993	72	constructs	construct	NNS
cord-256444-grw5s2pf	994	1	(	(	-LRB-
cord-256444-grw5s2pf	994	2	Chang	Chang	NNP
cord-256444-grw5s2pf	994	3	et	et	NNP
cord-256444-grw5s2pf	994	4	al	al	NNP
cord-256444-grw5s2pf	994	5	.	.	NNP
cord-256444-grw5s2pf	994	6	,	,	,
cord-256444-grw5s2pf	994	7	1994	1994	CD
cord-256444-grw5s2pf	994	8	;	;	:
cord-256444-grw5s2pf	994	9	Luytjes	Luytjes	NNP
cord-256444-grw5s2pf	994	10	et	et	NNP
cord-256444-grw5s2pf	994	11	al	al	NNP
cord-256444-grw5s2pf	994	12	.	.	NNP
cord-256444-grw5s2pf	994	13	,	,	,
cord-256444-grw5s2pf	994	14	1996	1996	CD
cord-256444-grw5s2pf	994	15	)	)	-RRB-
cord-256444-grw5s2pf	994	16	.	.	.
cord-256444-grw5s2pf	995	1	Thus	thus	RB
cord-256444-grw5s2pf	995	2	,	,	,
cord-256444-grw5s2pf	995	3	this	this	DT
cord-256444-grw5s2pf	995	4	internal	internal	JJ
cord-256444-grw5s2pf	995	5	sequence	sequence	NN
cord-256444-grw5s2pf	995	6	probably	probably	RB
cord-256444-grw5s2pf	995	7	plays	play	VBZ
cord-256444-grw5s2pf	995	8	a	a	DT
cord-256444-grw5s2pf	995	9	role	role	NN
cord-256444-grw5s2pf	995	10	in	in	IN
cord-256444-grw5s2pf	995	11	maintaining	maintain	VBG
cord-256444-grw5s2pf	995	12	the	the	DT
cord-256444-grw5s2pf	995	13	overall	overall	JJ
cord-256444-grw5s2pf	995	14	RNA	RNA	NNP
cord-256444-grw5s2pf	995	15	conformation	conformation	NN
cord-256444-grw5s2pf	995	16	for	for	IN
cord-256444-grw5s2pf	995	17	some	some	DT
cord-256444-grw5s2pf	995	18	DI	DI	NNP
cord-256444-grw5s2pf	995	19	RNAs	rna	NNS
cord-256444-grw5s2pf	995	20	(	(	-LRB-
cord-256444-grw5s2pf	995	21	Y.	Y.	NNP
cord-256444-grw5s2pf	995	22	N.	N.	NNP
cord-256444-grw5s2pf	995	23	.	.	.
cord-256444-grw5s2pf	996	1	Again	again	RB
cord-256444-grw5s2pf	996	2	,	,	,
cord-256444-grw5s2pf	996	3	the	the	DT
cord-256444-grw5s2pf	996	4	requirement	requirement	NN
cord-256444-grw5s2pf	996	5	of	of	IN
cord-256444-grw5s2pf	996	6	a	a	DT
cord-256444-grw5s2pf	996	7	3	3	CD
cord-256444-grw5s2pf	996	8	'	'	NN
cord-256444-grw5s2pf	996	9	end	end	NN
cord-256444-grw5s2pf	996	10	sequence	sequence	NN
cord-256444-grw5s2pf	996	11	(	(	-LRB-
cord-256444-grw5s2pf	996	12	436	436	CD
cord-256444-grw5s2pf	996	13	nt	nt	NN
cord-256444-grw5s2pf	996	14	)	)	-RRB-
cord-256444-grw5s2pf	996	15	that	that	WDT
cord-256444-grw5s2pf	996	16	is	be	VBZ
cord-256444-grw5s2pf	996	17	longer	long	JJR
cord-256444-grw5s2pf	996	18	than	than	IN
cord-256444-grw5s2pf	996	19	that	that	DT
cord-256444-grw5s2pf	996	20	required	require	VBN
cord-256444-grw5s2pf	996	21	for	for	IN
cord-256444-grw5s2pf	996	22	negative	negative	JJ
cord-256444-grw5s2pf	996	23	-	-	HYPH
cord-256444-grw5s2pf	996	24	strand	strand	NN
cord-256444-grw5s2pf	996	25	RNA	RNA	NNP
cord-256444-grw5s2pf	996	26	synthesis	synthesis	NN
cord-256444-grw5s2pf	996	27	(	(	-LRB-
cord-256444-grw5s2pf	996	28	55	55	CD
cord-256444-grw5s2pf	996	29	nt	nt	NN
cord-256444-grw5s2pf	996	30	)	)	-RRB-
cord-256444-grw5s2pf	996	31	is	be	VBZ
cord-256444-grw5s2pf	996	32	a	a	DT
cord-256444-grw5s2pf	996	33	surprise	surprise	NN
cord-256444-grw5s2pf	996	34	.	.	.
cord-256444-grw5s2pf	997	1	These	these	DT
cord-256444-grw5s2pf	997	2	3	3	CD
cord-256444-grw5s2pf	997	3	'	'	POS
cord-256444-grw5s2pf	997	4	end	end	NN
cord-256444-grw5s2pf	997	5	sequences	sequence	NNS
cord-256444-grw5s2pf	997	6	are	be	VBP
cord-256444-grw5s2pf	997	7	probably	probably	RB
cord-256444-grw5s2pf	997	8	required	require	VBN
cord-256444-grw5s2pf	997	9	for	for	IN
cord-256444-grw5s2pf	997	10	positive	positive	JJ
cord-256444-grw5s2pf	997	11	-	-	HYPH
cord-256444-grw5s2pf	997	12	strand	strand	NN
cord-256444-grw5s2pf	997	13	RNA	RNA	NNP
cord-256444-grw5s2pf	997	14	synthesis	synthesis	NN
cord-256444-grw5s2pf	997	15	during	during	IN
cord-256444-grw5s2pf	997	16	RNA	RNA	NNP
cord-256444-grw5s2pf	997	17	replication	replication	NN
cord-256444-grw5s2pf	997	18	.	.	.
cord-256444-grw5s2pf	998	1	This	this	DT
cord-256444-grw5s2pf	998	2	finding	finding	NN
cord-256444-grw5s2pf	998	3	is	be	VBZ
cord-256444-grw5s2pf	998	4	reminiscent	reminiscent	JJ
cord-256444-grw5s2pf	998	5	of	of	IN
cord-256444-grw5s2pf	998	6	the	the	DT
cord-256444-grw5s2pf	998	7	sequence	sequence	NN
cord-256444-grw5s2pf	998	8	requirement	requirement	NN
cord-256444-grw5s2pf	998	9	for	for	IN
cord-256444-grw5s2pf	998	10	RNA	RNA	NNP
cord-256444-grw5s2pf	998	11	transcription	transcription	NN
cord-256444-grw5s2pf	998	12	discussed	discuss	VBN
cord-256444-grw5s2pf	998	13	above	above	RB
cord-256444-grw5s2pf	998	14	and	and	CC
cord-256444-grw5s2pf	998	15	suggests	suggest	VBZ
cord-256444-grw5s2pf	998	16	that	that	IN
cord-256444-grw5s2pf	998	17	there	there	EX
cord-256444-grw5s2pf	998	18	is	be	VBZ
cord-256444-grw5s2pf	998	19	a	a	DT
cord-256444-grw5s2pf	998	20	direct	direct	JJ
cord-256444-grw5s2pf	998	21	or	or	CC
cord-256444-grw5s2pf	998	22	indirect	indirect	JJ
cord-256444-grw5s2pf	998	23	RNA	RNA	NNP
cord-256444-grw5s2pf	998	24	-	-	HYPH
cord-256444-grw5s2pf	998	25	RNA	RNA	NNP
cord-256444-grw5s2pf	998	26	interaction	interaction	NN
cord-256444-grw5s2pf	998	27	between	between	IN
cord-256444-grw5s2pf	998	28	the	the	DT
cord-256444-grw5s2pf	998	29	5	5	CD
cord-256444-grw5s2pf	998	30	'	'	''
cord-256444-grw5s2pf	998	31	and	and	CC
cord-256444-grw5s2pf	998	32	3	3	CD
cord-256444-grw5s2pf	998	33	'	'	''
cord-256444-grw5s2pf	998	34	ends	end	NNS
cord-256444-grw5s2pf	998	35	during	during	IN
cord-256444-grw5s2pf	998	36	RNA	RNA	NNP
cord-256444-grw5s2pf	998	37	replication	replication	NN
cord-256444-grw5s2pf	998	38	.	.	.
cord-256444-grw5s2pf	999	1	These	these	DT
cord-256444-grw5s2pf	999	2	DI	DI	NNP
cord-256444-grw5s2pf	999	3	RNA	RNA	NNP
cord-256444-grw5s2pf	999	4	studies	study	NNS
cord-256444-grw5s2pf	999	5	also	also	RB
cord-256444-grw5s2pf	999	6	showed	show	VBD
cord-256444-grw5s2pf	999	7	that	that	IN
cord-256444-grw5s2pf	999	8	replication	replication	NN
cord-256444-grw5s2pf	999	9	of	of	IN
cord-256444-grw5s2pf	999	10	DI	DI	NNP
cord-256444-grw5s2pf	999	11	RNA	RNA	NNP
cord-256444-grw5s2pf	999	12	is	be	VBZ
cord-256444-grw5s2pf	999	13	inhibited	inhibit	VBN
cord-256444-grw5s2pf	999	14	when	when	WRB
cord-256444-grw5s2pf	999	15	an	an	DT
cord-256444-grw5s2pf	999	16	mRNA	mrna	NN
cord-256444-grw5s2pf	999	17	is	be	VBZ
cord-256444-grw5s2pf	999	18	transcribed	transcribe	VBN
cord-256444-grw5s2pf	999	19	from	from	IN
cord-256444-grw5s2pf	999	20	an	an	DT
cord-256444-grw5s2pf	999	21	IG	IG	NNP
cord-256444-grw5s2pf	999	22	site	site	NN
cord-256444-grw5s2pf	999	23	within	within	IN
cord-256444-grw5s2pf	999	24	the	the	DT
cord-256444-grw5s2pf	999	25	same	same	JJ
cord-256444-grw5s2pf	999	26	DI	DI	NNP
cord-256444-grw5s2pf	999	27	RNA	RNA	NNP
cord-256444-grw5s2pf	999	28	,	,	,
cord-256444-grw5s2pf	999	29	and	and	CC
cord-256444-grw5s2pf	999	30	that	that	IN
cord-256444-grw5s2pf	999	31	the	the	DT
cord-256444-grw5s2pf	999	32	mechanism	mechanism	NN
cord-256444-grw5s2pf	999	33	of	of	IN
cord-256444-grw5s2pf	999	34	inhibition	inhibition	NN
cord-256444-grw5s2pf	999	35	is	be	VBZ
cord-256444-grw5s2pf	999	36	due	due	JJ
cord-256444-grw5s2pf	999	37	not	not	RB
cord-256444-grw5s2pf	999	38	to	to	TO
cord-256444-grw5s2pf	999	39	competition	competition	NN
cord-256444-grw5s2pf	999	40	for	for	IN
cord-256444-grw5s2pf	999	41	the	the	DT
cord-256444-grw5s2pf	999	42	same	same	JJ
cord-256444-grw5s2pf	999	43	transcription	transcription	NN
cord-256444-grw5s2pf	999	44	machinery	machinery	NN
cord-256444-grw5s2pf	999	45	(	(	-LRB-
cord-256444-grw5s2pf	999	46	Jeong	Jeong	NNP
cord-256444-grw5s2pf	999	47	and	and	CC
cord-256444-grw5s2pf	999	48	Makino	Makino	NNP
cord-256444-grw5s2pf	999	49	,	,	,
cord-256444-grw5s2pf	999	50	19921	19921	CD
cord-256444-grw5s2pf	999	51	,	,	,
cord-256444-grw5s2pf	999	52	but	but	CC
cord-256444-grw5s2pf	999	53	most	most	RBS
cord-256444-grw5s2pf	999	54	likely	likely	JJ
cord-256444-grw5s2pf	999	55	to	to	IN
cord-256444-grw5s2pf	999	56	the	the	DT
cord-256444-grw5s2pf	999	57	overlap	overlap	NN
cord-256444-grw5s2pf	999	58	of	of	IN
cord-256444-grw5s2pf	999	59	the	the	DT
cord-256444-grw5s2pf	999	60	cis	cis	NNP
cord-256444-grw5s2pf	999	61	-	-	HYPH
cord-256444-grw5s2pf	999	62	acting	act	VBG
cord-256444-grw5s2pf	999	63	signals	signal	NNS
cord-256444-grw5s2pf	999	64	for	for	IN
cord-256444-grw5s2pf	999	65	these	these	DT
cord-256444-grw5s2pf	999	66	two	two	CD
cord-256444-grw5s2pf	999	67	different	different	JJ
cord-256444-grw5s2pf	999	68	processes	process	NNS
cord-256444-grw5s2pf	999	69	.	.	.
cord-256444-grw5s2pf	1000	1	However	however	RB
cord-256444-grw5s2pf	1000	2	,	,	,
cord-256444-grw5s2pf	1000	3	the	the	DT
cord-256444-grw5s2pf	1000	4	sequence	sequence	NN
cord-256444-grw5s2pf	1000	5	requirements	requirement	NNS
cord-256444-grw5s2pf	1000	6	for	for	IN
cord-256444-grw5s2pf	1000	7	replication	replication	NN
cord-256444-grw5s2pf	1000	8	and	and	CC
cord-256444-grw5s2pf	1000	9	transcription	transcription	NN
cord-256444-grw5s2pf	1000	10	are	be	VBP
cord-256444-grw5s2pf	1000	11	different	different	JJ
cord-256444-grw5s2pf	1000	12	,	,	,
cord-256444-grw5s2pf	1000	13	indicating	indicate	VBG
cord-256444-grw5s2pf	1000	14	that	that	IN
cord-256444-grw5s2pf	1000	15	these	these	DT
cord-256444-grw5s2pf	1000	16	two	two	CD
cord-256444-grw5s2pf	1000	17	processes	process	NNS
cord-256444-grw5s2pf	1000	18	are	be	VBP
cord-256444-grw5s2pf	1000	19	distinguishable	distinguishable	JJ
cord-256444-grw5s2pf	1000	20	.	.	.
cord-256444-grw5s2pf	1001	1	The	the	DT
cord-256444-grw5s2pf	1001	2	mRNA	mrna	NN
cord-256444-grw5s2pf	1001	3	transcription	transcription	NN
cord-256444-grw5s2pf	1001	4	and	and	CC
cord-256444-grw5s2pf	1001	5	genomic	genomic	JJ
cord-256444-grw5s2pf	1001	6	RNA	RNA	NNP
cord-256444-grw5s2pf	1001	7	replication	replication	NN
cord-256444-grw5s2pf	1001	8	may	may	MD
cord-256444-grw5s2pf	1001	9	be	be	VB
cord-256444-grw5s2pf	1001	10	regulated	regulate	VBN
cord-256444-grw5s2pf	1001	11	by	by	IN
cord-256444-grw5s2pf	1001	12	the	the	DT
cord-256444-grw5s2pf	1001	13	same	same	JJ
cord-256444-grw5s2pf	1001	14	mechanism	mechanism	NN
cord-256444-grw5s2pf	1001	15	throughout	throughout	IN
cord-256444-grw5s2pf	1001	16	most	most	JJS
cord-256444-grw5s2pf	1001	17	of	of	IN
cord-256444-grw5s2pf	1001	18	the	the	DT
cord-256444-grw5s2pf	1001	19	viral	viral	JJ
cord-256444-grw5s2pf	1001	20	replication	replication	NN
cord-256444-grw5s2pf	1001	21	cycle	cycle	NN
cord-256444-grw5s2pf	1001	22	.	.	.
cord-256444-grw5s2pf	1002	1	However	however	RB
cord-256444-grw5s2pf	1002	2	,	,	,
cord-256444-grw5s2pf	1002	3	the	the	DT
cord-256444-grw5s2pf	1002	4	ratio	ratio	NN
cord-256444-grw5s2pf	1002	5	between	between	IN
cord-256444-grw5s2pf	1002	6	the	the	DT
cord-256444-grw5s2pf	1002	7	genomic	genomic	JJ
cord-256444-grw5s2pf	1002	8	RNA	RNA	NNP
cord-256444-grw5s2pf	1002	9	and	and	CC
cord-256444-grw5s2pf	1002	10	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1002	11	RNAs	RNAs	NNPS
cord-256444-grw5s2pf	1002	12	,	,	,
cord-256444-grw5s2pf	1002	13	as	as	IN
cord-256444-grw5s2pf	1002	14	detected	detect	VBN
cord-256444-grw5s2pf	1002	15	by	by	IN
cord-256444-grw5s2pf	1002	16	radioactive	radioactive	JJ
cord-256444-grw5s2pf	1002	17	uridine	uridine	NN
cord-256444-grw5s2pf	1002	18	incorporation	incorporation	NN
cord-256444-grw5s2pf	1002	19	,	,	,
cord-256444-grw5s2pf	1002	20	increases	increase	NNS
cord-256444-grw5s2pf	1002	21	during	during	IN
cord-256444-grw5s2pf	1002	22	the	the	DT
cord-256444-grw5s2pf	1002	23	late	late	JJ
cord-256444-grw5s2pf	1002	24	stages	stage	NNS
cord-256444-grw5s2pf	1002	25	of	of	IN
cord-256444-grw5s2pf	1002	26	the	the	DT
cord-256444-grw5s2pf	1002	27	BCV	BCV	NNP
cord-256444-grw5s2pf	1002	28	replication	replication	NN
cord-256444-grw5s2pf	1002	29	cycle	cycle	NN
cord-256444-grw5s2pf	1002	30	(	(	-LRB-
cord-256444-grw5s2pf	1002	31	Keck	Keck	NNP
cord-256444-grw5s2pf	1002	32	et	et	NNP
cord-256444-grw5s2pf	1002	33	al	al	NNP
cord-256444-grw5s2pf	1002	34	.	.	NNP
cord-256444-grw5s2pf	1002	35	,	,	,
cord-256444-grw5s2pf	1002	36	1988a	1988a	CD
cord-256444-grw5s2pf	1002	37	)	)	-RRB-
cord-256444-grw5s2pf	1002	38	,	,	,
cord-256444-grw5s2pf	1002	39	suggesting	suggest	VBG
cord-256444-grw5s2pf	1002	40	a	a	DT
cord-256444-grw5s2pf	1002	41	possible	possible	JJ
cord-256444-grw5s2pf	1002	42	switching	switching	NN
cord-256444-grw5s2pf	1002	43	mechanism	mechanism	NN
cord-256444-grw5s2pf	1002	44	from	from	IN
cord-256444-grw5s2pf	1002	45	transcription	transcription	NN
cord-256444-grw5s2pf	1002	46	to	to	IN
cord-256444-grw5s2pf	1002	47	replication	replication	NN
cord-256444-grw5s2pf	1002	48	.	.	.
cord-256444-grw5s2pf	1003	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1003	2	has	have	VBZ
cord-256444-grw5s2pf	1003	3	been	be	VBN
cord-256444-grw5s2pf	1003	4	shown	show	VBN
cord-256444-grw5s2pf	1003	5	that	that	IN
cord-256444-grw5s2pf	1003	6	genomic	genomic	JJ
cord-256444-grw5s2pf	1003	7	RNA	rna	NN
cord-256444-grw5s2pf	1003	8	replication	replication	NN
cord-256444-grw5s2pf	1003	9	is	be	VBZ
cord-256444-grw5s2pf	1003	10	coupled	couple	VBN
cord-256444-grw5s2pf	1003	11	to	to	IN
cord-256444-grw5s2pf	1003	12	encapsidation	encapsidation	NN
cord-256444-grw5s2pf	1003	13	,	,	,
cord-256444-grw5s2pf	1003	14	since	since	IN
cord-256444-grw5s2pf	1003	15	no	no	DT
cord-256444-grw5s2pf	1003	16	free	free	JJ
cord-256444-grw5s2pf	1003	17	genomic	genomic	JJ
cord-256444-grw5s2pf	1003	18	RNA	RNA	NNP
cord-256444-grw5s2pf	1003	19	is	be	VBZ
cord-256444-grw5s2pf	1003	20	found	find	VBN
cord-256444-grw5s2pf	1003	21	.	.	.
cord-256444-grw5s2pf	1004	1	Since	since	IN
cord-256444-grw5s2pf	1004	2	the	the	DT
cord-256444-grw5s2pf	1004	3	encapsidation	encapsidation	NN
cord-256444-grw5s2pf	1004	4	of	of	IN
cord-256444-grw5s2pf	1004	5	RNA	RNA	NNP
cord-256444-grw5s2pf	1004	6	requires	require	VBZ
cord-256444-grw5s2pf	1004	7	the	the	DT
cord-256444-grw5s2pf	1004	8	N	N	NNP
cord-256444-grw5s2pf	1004	9	protein	protein	NN
cord-256444-grw5s2pf	1004	10	,	,	,
cord-256444-grw5s2pf	1004	11	this	this	DT
cord-256444-grw5s2pf	1004	12	protein	protein	NN
cord-256444-grw5s2pf	1004	13	may	may	MD
cord-256444-grw5s2pf	1004	14	participate	participate	VB
cord-256444-grw5s2pf	1004	15	in	in	IN
cord-256444-grw5s2pf	1004	16	the	the	DT
cord-256444-grw5s2pf	1004	17	regulation	regulation	NN
cord-256444-grw5s2pf	1004	18	of	of	IN
cord-256444-grw5s2pf	1004	19	switching	switch	VBG
cord-256444-grw5s2pf	1004	20	between	between	IN
cord-256444-grw5s2pf	1004	21	transcription	transcription	NN
cord-256444-grw5s2pf	1004	22	and	and	CC
cord-256444-grw5s2pf	1004	23	replication	replication	NN
cord-256444-grw5s2pf	1004	24	.	.	.
cord-256444-grw5s2pf	1005	1	The	the	DT
cord-256444-grw5s2pf	1005	2	sequences	sequence	NNS
cord-256444-grw5s2pf	1005	3	of	of	IN
cord-256444-grw5s2pf	1005	4	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1005	5	mRNAs	mrnas	WDT
cord-256444-grw5s2pf	1005	6	usually	usually	RB
cord-256444-grw5s2pf	1005	7	start	start	VBP
cord-256444-grw5s2pf	1005	8	from	from	IN
cord-256444-grw5s2pf	1005	9	a	a	DT
cord-256444-grw5s2pf	1005	10	site	site	NN
cord-256444-grw5s2pf	1005	11	immediately	immediately	RB
cord-256444-grw5s2pf	1005	12	upstream	upstream	RB
cord-256444-grw5s2pf	1005	13	of	of	IN
cord-256444-grw5s2pf	1005	14	a	a	DT
cord-256444-grw5s2pf	1005	15	gene	gene	NN
cord-256444-grw5s2pf	1005	16	.	.	.
cord-256444-grw5s2pf	1006	1	These	these	DT
cord-256444-grw5s2pf	1006	2	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	1006	3	,	,	,
cord-256444-grw5s2pf	1006	4	except	except	IN
cord-256444-grw5s2pf	1006	5	for	for	IN
cord-256444-grw5s2pf	1006	6	the	the	DT
cord-256444-grw5s2pf	1006	7	smallest	small	JJS
cord-256444-grw5s2pf	1006	8	mRNA	mrna	NN
cord-256444-grw5s2pf	1006	9	,	,	,
cord-256444-grw5s2pf	1006	10	are	be	VBP
cord-256444-grw5s2pf	1006	11	structurally	structurally	RB
cord-256444-grw5s2pf	1006	12	polycistronic	polycistronic	JJ
cord-256444-grw5s2pf	1006	13	,	,	,
cord-256444-grw5s2pf	1006	14	containing	contain	VBG
cord-256444-grw5s2pf	1006	15	multiple	multiple	JJ
cord-256444-grw5s2pf	1006	16	ORFs	orf	NNS
cord-256444-grw5s2pf	1006	17	.	.	.
cord-256444-grw5s2pf	1007	1	Only	only	RB
cord-256444-grw5s2pf	1007	2	the	the	DT
cord-256444-grw5s2pf	1007	3	5	5	CD
cord-256444-grw5s2pf	1007	4	'	'	''
cord-256444-grw5s2pf	1007	5	most	most	JJS
cord-256444-grw5s2pf	1007	6	ORF	ORF	NNP
cord-256444-grw5s2pf	1007	7	in	in	IN
cord-256444-grw5s2pf	1007	8	the	the	DT
cord-256444-grw5s2pf	1007	9	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	1007	10	is	be	VBZ
cord-256444-grw5s2pf	1007	11	translatable	translatable	JJ
cord-256444-grw5s2pf	1007	12	;	;	:
cord-256444-grw5s2pf	1007	13	the	the	DT
cord-256444-grw5s2pf	1007	14	remaining	remain	VBG
cord-256444-grw5s2pf	1007	15	ORFs	orf	NNS
cord-256444-grw5s2pf	1007	16	are	be	VBP
cord-256444-grw5s2pf	1007	17	usually	usually	RB
cord-256444-grw5s2pf	1007	18	functionally	functionally	RB
cord-256444-grw5s2pf	1007	19	silent	silent	JJ
cord-256444-grw5s2pf	1007	20	.	.	.
cord-256444-grw5s2pf	1008	1	Thus	thus	RB
cord-256444-grw5s2pf	1008	2	,	,	,
cord-256444-grw5s2pf	1008	3	most	most	JJS
cord-256444-grw5s2pf	1008	4	of	of	IN
cord-256444-grw5s2pf	1008	5	these	these	DT
cord-256444-grw5s2pf	1008	6	mRNAs	mrna	NNS
cord-256444-grw5s2pf	1008	7	are	be	VBP
cord-256444-grw5s2pf	1008	8	functionally	functionally	RB
cord-256444-grw5s2pf	1008	9	monocistronic	monocistronic	JJ
cord-256444-grw5s2pf	1008	10	(	(	-LRB-
cord-256444-grw5s2pf	1008	11	see	see	VB
cord-256444-grw5s2pf	1008	12	Fig	Fig	NNP
cord-256444-grw5s2pf	1008	13	.	.	NNP
cord-256444-grw5s2pf	1008	14	7	7	CD
cord-256444-grw5s2pf	1008	15	)	)	-RRB-
cord-256444-grw5s2pf	1008	16	.	.	.
cord-256444-grw5s2pf	1009	1	The	the	DT
cord-256444-grw5s2pf	1009	2	S	S	NNP
cord-256444-grw5s2pf	1009	3	,	,	,
cord-256444-grw5s2pf	1009	4	HE	HE	NNP
cord-256444-grw5s2pf	1009	5	,	,	,
cord-256444-grw5s2pf	1009	6	M	M	NNP
cord-256444-grw5s2pf	1009	7	,	,	,
cord-256444-grw5s2pf	1009	8	and	and	CC
cord-256444-grw5s2pf	1009	9	N	n	CD
cord-256444-grw5s2pf	1009	10	proteins	protein	NNS
cord-256444-grw5s2pf	1009	11	,	,	,
cord-256444-grw5s2pf	1009	12	and	and	CC
cord-256444-grw5s2pf	1009	13	in	in	IN
cord-256444-grw5s2pf	1009	14	most	most	JJS
cord-256444-grw5s2pf	1009	15	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1009	16	the	the	DT
cord-256444-grw5s2pf	1009	17	E	e	NN
cord-256444-grw5s2pf	1009	18	protein	protein	NN
cord-256444-grw5s2pf	1009	19	,	,	,
cord-256444-grw5s2pf	1009	20	are	be	VBP
cord-256444-grw5s2pf	1009	21	translated	translate	VBN
cord-256444-grw5s2pf	1009	22	from	from	IN
cord-256444-grw5s2pf	1009	23	separate	separate	JJ
cord-256444-grw5s2pf	1009	24	mRNAs	mrna	NNS
cord-256444-grw5s2pf	1009	25	by	by	IN
cord-256444-grw5s2pf	1009	26	this	this	DT
cord-256444-grw5s2pf	1009	27	mechanism	mechanism	NN
cord-256444-grw5s2pf	1009	28	;	;	:
cord-256444-grw5s2pf	1009	29	initiation	initiation	NN
cord-256444-grw5s2pf	1009	30	of	of	IN
cord-256444-grw5s2pf	1009	31	their	-PRON-	PRP$
cord-256444-grw5s2pf	1009	32	translation	translation	NN
cord-256444-grw5s2pf	1009	33	is	be	VBZ
cord-256444-grw5s2pf	1009	34	unremarkable	unremarkable	JJ
cord-256444-grw5s2pf	1009	35	,	,	,
cord-256444-grw5s2pf	1009	36	utilizing	utilize	VBG
cord-256444-grw5s2pf	1009	37	a	a	DT
cord-256444-grw5s2pf	1009	38	cap	cap	NN
cord-256444-grw5s2pf	1009	39	-	-	HYPH
cord-256444-grw5s2pf	1009	40	dependent	dependent	JJ
cord-256444-grw5s2pf	1009	41	translation	translation	NN
cord-256444-grw5s2pf	1009	42	mechanism	mechanism	NN
cord-256444-grw5s2pf	1009	43	.	.	.
cord-256444-grw5s2pf	1010	1	Many	many	JJ
cord-256444-grw5s2pf	1010	2	ns	ns	IN
cord-256444-grw5s2pf	1010	3	proteins	protein	NNS
cord-256444-grw5s2pf	1010	4	,	,	,
cord-256444-grw5s2pf	1010	5	however	however	RB
cord-256444-grw5s2pf	1010	6	,	,	,
cord-256444-grw5s2pf	1010	7	are	be	VBP
cord-256444-grw5s2pf	1010	8	translated	translate	VBN
cord-256444-grw5s2pf	1010	9	from	from	IN
cord-256444-grw5s2pf	1010	10	truly	truly	RB
cord-256444-grw5s2pf	1010	11	polycistronic	polycistronic	NNP
cord-256444-grw5s2pf	1010	12	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	1010	13	,	,	,
cord-256444-grw5s2pf	1010	14	i.e.	i.e.	FW
cord-256444-grw5s2pf	1010	15	,	,	,
cord-256444-grw5s2pf	1010	16	two	two	CD
cord-256444-grw5s2pf	1010	17	or	or	CC
cord-256444-grw5s2pf	1010	18	three	three	CD
cord-256444-grw5s2pf	1010	19	proteins	protein	NNS
cord-256444-grw5s2pf	1010	20	are	be	VBP
cord-256444-grw5s2pf	1010	21	translated	translate	VBN
cord-256444-grw5s2pf	1010	22	from	from	IN
cord-256444-grw5s2pf	1010	23	the	the	DT
cord-256444-grw5s2pf	1010	24	same	same	JJ
cord-256444-grw5s2pf	1010	25	mRNA	mrna	NN
cord-256444-grw5s2pf	1010	26	.	.	.
cord-256444-grw5s2pf	1011	1	For	for	IN
cord-256444-grw5s2pf	1011	2	these	these	DT
cord-256444-grw5s2pf	1011	3	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	1011	4	,	,	,
cord-256444-grw5s2pf	1011	5	the	the	DT
cord-256444-grw5s2pf	1011	6	first	first	JJ
cord-256444-grw5s2pf	1011	7	ORF	ORF	NNP
cord-256444-grw5s2pf	1011	8	,	,	,
cord-256444-grw5s2pf	1011	9	e.g.	e.g.	RB
cord-256444-grw5s2pf	1011	10	,	,	,
cord-256444-grw5s2pf	1011	11	3a	3a	CD
cord-256444-grw5s2pf	1011	12	of	of	IN
cord-256444-grw5s2pf	1011	13	IBV	IBV	NNP
cord-256444-grw5s2pf	1011	14	or	or	CC
cord-256444-grw5s2pf	1011	15	5a	5a	CD
cord-256444-grw5s2pf	1011	16	of	of	IN
cord-256444-grw5s2pf	1011	17	MHV	MHV	NNP
cord-256444-grw5s2pf	1011	18	,	,	,
cord-256444-grw5s2pf	1011	19	is	be	VBZ
cord-256444-grw5s2pf	1011	20	probably	probably	RB
cord-256444-grw5s2pf	1011	21	also	also	RB
cord-256444-grw5s2pf	1011	22	translated	translate	VBN
cord-256444-grw5s2pf	1011	23	by	by	IN
cord-256444-grw5s2pf	1011	24	the	the	DT
cord-256444-grw5s2pf	1011	25	same	same	JJ
cord-256444-grw5s2pf	1011	26	mechanism	mechanism	NN
cord-256444-grw5s2pf	1011	27	as	as	IN
cord-256444-grw5s2pf	1011	28	the	the	DT
cord-256444-grw5s2pf	1011	29	structural	structural	JJ
cord-256444-grw5s2pf	1011	30	protein	protein	NN
cord-256444-grw5s2pf	1011	31	genes	gene	NNS
cord-256444-grw5s2pf	1011	32	.	.	.
cord-256444-grw5s2pf	1012	1	For	for	IN
cord-256444-grw5s2pf	1012	2	internal	internal	JJ
cord-256444-grw5s2pf	1012	3	ORFs	orf	NNS
cord-256444-grw5s2pf	1012	4	,	,	,
cord-256444-grw5s2pf	1012	5	e.g.	e.g.	RB
cord-256444-grw5s2pf	1012	6	,	,	,
cord-256444-grw5s2pf	1012	7	E	e	NN
cord-256444-grw5s2pf	1012	8	protein	protein	NN
cord-256444-grw5s2pf	1012	9	of	of	IN
cord-256444-grw5s2pf	1012	10	IBV	IBV	NNP
cord-256444-grw5s2pf	1012	11	and	and	CC
cord-256444-grw5s2pf	1012	12	MHV	MHV	NNP
cord-256444-grw5s2pf	1012	13	,	,	,
cord-256444-grw5s2pf	1012	14	an	an	DT
cord-256444-grw5s2pf	1012	15	alternative	alternative	JJ
cord-256444-grw5s2pf	1012	16	mechanism	mechanism	NN
cord-256444-grw5s2pf	1012	17	must	must	MD
cord-256444-grw5s2pf	1012	18	be	be	VB
cord-256444-grw5s2pf	1012	19	employed	employ	VBN
cord-256444-grw5s2pf	1012	20	to	to	TO
cord-256444-grw5s2pf	1012	21	initiate	initiate	VB
cord-256444-grw5s2pf	1012	22	translation	translation	NN
cord-256444-grw5s2pf	1012	23	internally	internally	RB
cord-256444-grw5s2pf	1012	24	.	.	.
cord-256444-grw5s2pf	1013	1	One	one	CD
cord-256444-grw5s2pf	1013	2	characteristic	characteristic	NN
cord-256444-grw5s2pf	1013	3	of	of	IN
cord-256444-grw5s2pf	1013	4	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1013	5	mRNAs	mRNAs	''
cord-256444-grw5s2pf	1013	6	is	be	VBZ
cord-256444-grw5s2pf	1013	7	the	the	DT
cord-256444-grw5s2pf	1013	8	presence	presence	NN
cord-256444-grw5s2pf	1013	9	of	of	IN
cord-256444-grw5s2pf	1013	10	the	the	DT
cord-256444-grw5s2pf	1013	11	leader	leader	NN
cord-256444-grw5s2pf	1013	12	RNA	RNA	NNP
cord-256444-grw5s2pf	1013	13	sequence	sequence	NN
cord-256444-grw5s2pf	1013	14	at	at	IN
cord-256444-grw5s2pf	1013	15	the	the	DT
cord-256444-grw5s2pf	1013	16	5	5	CD
cord-256444-grw5s2pf	1013	17	'	'	NN
cord-256444-grw5s2pf	1013	18	end	end	NN
cord-256444-grw5s2pf	1013	19	,	,	,
cord-256444-grw5s2pf	1013	20	which	which	WDT
cord-256444-grw5s2pf	1013	21	not	not	RB
cord-256444-grw5s2pf	1013	22	only	only	RB
cord-256444-grw5s2pf	1013	23	participates	participate	VBZ
cord-256444-grw5s2pf	1013	24	in	in	IN
cord-256444-grw5s2pf	1013	25	RNA	RNA	NNP
cord-256444-grw5s2pf	1013	26	transcription	transcription	NN
cord-256444-grw5s2pf	1013	27	,	,	,
cord-256444-grw5s2pf	1013	28	but	but	CC
cord-256444-grw5s2pf	1013	29	also	also	RB
cord-256444-grw5s2pf	1013	30	regulates	regulate	VBZ
cord-256444-grw5s2pf	1013	31	the	the	DT
cord-256444-grw5s2pf	1013	32	efficiency	efficiency	NN
cord-256444-grw5s2pf	1013	33	of	of	IN
cord-256444-grw5s2pf	1013	34	translation	translation	NN
cord-256444-grw5s2pf	1013	35	.	.	.
cord-256444-grw5s2pf	1014	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1014	2	has	have	VBZ
cord-256444-grw5s2pf	1014	3	been	be	VBN
cord-256444-grw5s2pf	1014	4	shown	show	VBN
cord-256444-grw5s2pf	1014	5	that	that	IN
cord-256444-grw5s2pf	1014	6	the	the	DT
cord-256444-grw5s2pf	1014	7	presence	presence	NN
cord-256444-grw5s2pf	1014	8	of	of	IN
cord-256444-grw5s2pf	1014	9	the	the	DT
cord-256444-grw5s2pf	1014	10	MHV	MHV	NNP
cord-256444-grw5s2pf	1014	11	leader	leader	NN
cord-256444-grw5s2pf	1014	12	sequence	sequence	NN
cord-256444-grw5s2pf	1014	13	on	on	IN
cord-256444-grw5s2pf	1014	14	a	a	DT
cord-256444-grw5s2pf	1014	15	heterologous	heterologous	JJ
cord-256444-grw5s2pf	1014	16	mRNA	mrna	NN
cord-256444-grw5s2pf	1014	17	in	in	IN
cord-256444-grw5s2pf	1014	18	a	a	DT
cord-256444-grw5s2pf	1014	19	chimeric	chimeric	JJ
cord-256444-grw5s2pf	1014	20	RNA	RNA	NNP
cord-256444-grw5s2pf	1014	21	construct	construct	NN
cord-256444-grw5s2pf	1014	22	can	can	MD
cord-256444-grw5s2pf	1014	23	enhance	enhance	VB
cord-256444-grw5s2pf	1014	24	its	-PRON-	PRP$
cord-256444-grw5s2pf	1014	25	translation	translation	NN
cord-256444-grw5s2pf	1014	26	in	in	IN
cord-256444-grw5s2pf	1014	27	virus	virus	NN
cord-256444-grw5s2pf	1014	28	-	-	HYPH
cord-256444-grw5s2pf	1014	29	infected	infect	VBN
cord-256444-grw5s2pf	1014	30	cell	cell	NN
cord-256444-grw5s2pf	1014	31	lysates	lysate	NNS
cord-256444-grw5s2pf	1014	32	but	but	CC
cord-256444-grw5s2pf	1014	33	not	not	RB
cord-256444-grw5s2pf	1014	34	in	in	IN
cord-256444-grw5s2pf	1014	35	uninfected	uninfected	JJ
cord-256444-grw5s2pf	1014	36	cell	cell	NN
cord-256444-grw5s2pf	1014	37	lysates	lysate	NNS
cord-256444-grw5s2pf	1015	1	(	(	-LRB-
cord-256444-grw5s2pf	1015	2	Tahara	Tahara	NNP
cord-256444-grw5s2pf	1015	3	et	et	FW
cord-256444-grw5s2pf	1015	4	al	al	NNP
cord-256444-grw5s2pf	1015	5	.	.	NNP
cord-256444-grw5s2pf	1015	6	,	,	,
cord-256444-grw5s2pf	1015	7	1994	1994	CD
cord-256444-grw5s2pf	1015	8	)	)	-RRB-
cord-256444-grw5s2pf	1015	9	.	.	.
cord-256444-grw5s2pf	1016	1	This	this	DT
cord-256444-grw5s2pf	1016	2	effect	effect	NN
cord-256444-grw5s2pf	1016	3	conceivably	conceivably	RB
cord-256444-grw5s2pf	1016	4	will	will	MD
cord-256444-grw5s2pf	1016	5	enable	enable	VB
cord-256444-grw5s2pf	1016	6	the	the	DT
cord-256444-grw5s2pf	1016	7	efficient	efficient	JJ
cord-256444-grw5s2pf	1016	8	translation	translation	NN
cord-256444-grw5s2pf	1016	9	of	of	IN
cord-256444-grw5s2pf	1016	10	viral	viral	JJ
cord-256444-grw5s2pf	1016	11	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	1016	12	in	in	IN
cord-256444-grw5s2pf	1016	13	the	the	DT
cord-256444-grw5s2pf	1016	14	face	face	NN
cord-256444-grw5s2pf	1016	15	of	of	IN
cord-256444-grw5s2pf	1016	16	shutoff	shutoff	NN
cord-256444-grw5s2pf	1016	17	of	of	IN
cord-256444-grw5s2pf	1016	18	translation	translation	NN
cord-256444-grw5s2pf	1016	19	of	of	IN
cord-256444-grw5s2pf	1016	20	cellular	cellular	NN
cord-256444-grw5s2pf	1016	21	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	1016	22	in	in	IN
cord-256444-grw5s2pf	1016	23	the	the	DT
cord-256444-grw5s2pf	1016	24	infected	infected	JJ
cord-256444-grw5s2pf	1016	25	cells	cell	NNS
cord-256444-grw5s2pf	1017	1	(	(	-LRB-
cord-256444-grw5s2pf	1017	2	Siddell	Siddell	NNP
cord-256444-grw5s2pf	1017	3	et	et	FW
cord-256444-grw5s2pf	1017	4	al	al	NNP
cord-256444-grw5s2pf	1017	5	.	.	NNP
cord-256444-grw5s2pf	1017	6	,	,	,
cord-256444-grw5s2pf	1017	7	1980	1980	CD
cord-256444-grw5s2pf	1017	8	;	;	:
cord-256444-grw5s2pf	1017	9	Hilton	Hilton	NNP
cord-256444-grw5s2pf	1017	10	et	et	NNP
cord-256444-grw5s2pf	1017	11	al	al	NNP
cord-256444-grw5s2pf	1017	12	.	.	NNP
cord-256444-grw5s2pf	1017	13	,	,	,
cord-256444-grw5s2pf	1017	14	1986	1986	CD
cord-256444-grw5s2pf	1017	15	)	)	-RRB-
cord-256444-grw5s2pf	1017	16	.	.	.
cord-256444-grw5s2pf	1018	1	The	the	DT
cord-256444-grw5s2pf	1018	2	mechanism	mechanism	NN
cord-256444-grw5s2pf	1018	3	of	of	IN
cord-256444-grw5s2pf	1018	4	translational	translational	JJ
cord-256444-grw5s2pf	1018	5	enhancement	enhancement	NN
cord-256444-grw5s2pf	1018	6	by	by	IN
cord-256444-grw5s2pf	1018	7	the	the	DT
cord-256444-grw5s2pf	1018	8	leader	leader	NN
cord-256444-grw5s2pf	1018	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1018	10	has	have	VBZ
cord-256444-grw5s2pf	1018	11	not	not	RB
cord-256444-grw5s2pf	1018	12	been	be	VBN
cord-256444-grw5s2pf	1018	13	determined	determine	VBN
cord-256444-grw5s2pf	1018	14	.	.	.
cord-256444-grw5s2pf	1019	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1019	2	has	have	VBZ
cord-256444-grw5s2pf	1019	3	been	be	VBN
cord-256444-grw5s2pf	1019	4	shown	show	VBN
cord-256444-grw5s2pf	1019	5	that	that	IN
cord-256444-grw5s2pf	1019	6	during	during	IN
cord-256444-grw5s2pf	1019	7	persistent	persistent	JJ
cord-256444-grw5s2pf	1019	8	infection	infection	NN
cord-256444-grw5s2pf	1019	9	of	of	IN
cord-256444-grw5s2pf	1019	10	BCV	BCV	NNP
cord-256444-grw5s2pf	1019	11	,	,	,
cord-256444-grw5s2pf	1019	12	the	the	DT
cord-256444-grw5s2pf	1019	13	leader	leader	NN
cord-256444-grw5s2pf	1019	14	RNA	RNA	NNP
cord-256444-grw5s2pf	1019	15	sequence	sequence	NN
cord-256444-grw5s2pf	1019	16	underwent	undergo	VBD
cord-256444-grw5s2pf	1019	17	frequent	frequent	JJ
cord-256444-grw5s2pf	1019	18	mutations	mutation	NNS
cord-256444-grw5s2pf	1019	19	(	(	-LRB-
cord-256444-grw5s2pf	1019	20	Hofmann	Hofmann	NNP
cord-256444-grw5s2pf	1019	21	et	et	NNP
cord-256444-grw5s2pf	1019	22	al	al	NNP
cord-256444-grw5s2pf	1019	23	.	.	NNP
cord-256444-grw5s2pf	1019	24	,	,	,
cord-256444-grw5s2pf	1019	25	1993b	1993b	CD
cord-256444-grw5s2pf	1019	26	)	)	-RRB-
cord-256444-grw5s2pf	1019	27	.	.	.
cord-256444-grw5s2pf	1020	1	One	one	CD
cord-256444-grw5s2pf	1020	2	of	of	IN
cord-256444-grw5s2pf	1020	3	these	these	DT
cord-256444-grw5s2pf	1020	4	mutants	mutant	NNS
cord-256444-grw5s2pf	1020	5	had	have	VBD
cord-256444-grw5s2pf	1020	6	an	an	DT
cord-256444-grw5s2pf	1020	7	intraleader	intraleader	NN
cord-256444-grw5s2pf	1020	8	short	short	JJ
cord-256444-grw5s2pf	1020	9	ORF	ORF	NNP
cord-256444-grw5s2pf	1020	10	and	and	CC
cord-256444-grw5s2pf	1020	11	a	a	DT
cord-256444-grw5s2pf	1020	12	lower	low	JJR
cord-256444-grw5s2pf	1020	13	translation	translation	NN
cord-256444-grw5s2pf	1020	14	efficiency	efficiency	NN
cord-256444-grw5s2pf	1020	15	,	,	,
cord-256444-grw5s2pf	1020	16	indicating	indicate	VBG
cord-256444-grw5s2pf	1020	17	that	that	IN
cord-256444-grw5s2pf	1020	18	the	the	DT
cord-256444-grw5s2pf	1020	19	leader	leader	NN
cord-256444-grw5s2pf	1020	20	sequence	sequence	NN
cord-256444-grw5s2pf	1020	21	in	in	IN
cord-256444-grw5s2pf	1020	22	-	-	HYPH
cord-256444-grw5s2pf	1020	23	deed	deed	NN
cord-256444-grw5s2pf	1020	24	can	can	MD
cord-256444-grw5s2pf	1020	25	modulate	modulate	VB
cord-256444-grw5s2pf	1020	26	translation	translation	NN
cord-256444-grw5s2pf	1020	27	.	.	.
cord-256444-grw5s2pf	1021	1	Another	another	DT
cord-256444-grw5s2pf	1021	2	region	region	NN
cord-256444-grw5s2pf	1021	3	which	which	WDT
cord-256444-grw5s2pf	1021	4	can	can	MD
cord-256444-grw5s2pf	1021	5	potentially	potentially	RB
cord-256444-grw5s2pf	1021	6	regulate	regulate	VB
cord-256444-grw5s2pf	1021	7	the	the	DT
cord-256444-grw5s2pf	1021	8	translation	translation	NN
cord-256444-grw5s2pf	1021	9	of	of	IN
cord-256444-grw5s2pf	1021	10	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1021	11	mRNAs	mRNAs	''
cord-256444-grw5s2pf	1021	12	is	be	VBZ
cord-256444-grw5s2pf	1021	13	the	the	DT
cord-256444-grw5s2pf	1021	14	5	5	CD
cord-256444-grw5s2pf	1021	15	'	'	POS
cord-256444-grw5s2pf	1021	16	UTR	UTR	NNP
cord-256444-grw5s2pf	1021	17	(	(	-LRB-
cord-256444-grw5s2pf	1021	18	other	other	JJ
cord-256444-grw5s2pf	1021	19	than	than	IN
cord-256444-grw5s2pf	1021	20	the	the	DT
cord-256444-grw5s2pf	1021	21	leader	leader	NN
cord-256444-grw5s2pf	1021	22	sequence	sequence	NN
cord-256444-grw5s2pf	1021	23	)	)	-RRB-
cord-256444-grw5s2pf	1021	24	of	of	IN
cord-256444-grw5s2pf	1021	25	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	1021	26	.	.	.
cord-256444-grw5s2pf	1022	1	The	the	DT
cord-256444-grw5s2pf	1022	2	genomic	genomic	JJ
cord-256444-grw5s2pf	1022	3	RNA	RNA	NNP
cord-256444-grw5s2pf	1022	4	(	(	-LRB-
cord-256444-grw5s2pf	1022	5	mRNA	mrna	NN
cord-256444-grw5s2pf	1022	6	1	1	CD
cord-256444-grw5s2pf	1022	7	)	)	-RRB-
cord-256444-grw5s2pf	1022	8	has	have	VBZ
cord-256444-grw5s2pf	1022	9	a	a	DT
cord-256444-grw5s2pf	1022	10	particularly	particularly	RB
cord-256444-grw5s2pf	1022	11	long	long	JJ
cord-256444-grw5s2pf	1022	12	5	5	CD
cord-256444-grw5s2pf	1022	13	'	'	''
cord-256444-grw5s2pf	1022	14	.	.	.
cord-256444-grw5s2pf	1023	1	An	an	DT
cord-256444-grw5s2pf	1023	2	MHV	MHV	NNP
cord-256444-grw5s2pf	1023	3	with	with	IN
cord-256444-grw5s2pf	1023	4	a	a	DT
cord-256444-grw5s2pf	1023	5	specific	specific	JJ
cord-256444-grw5s2pf	1023	6	point	point	NN
cord-256444-grw5s2pf	1023	7	mutation	mutation	NN
cord-256444-grw5s2pf	1023	8	within	within	IN
cord-256444-grw5s2pf	1023	9	the	the	DT
cord-256444-grw5s2pf	1023	10	5	5	CD
cord-256444-grw5s2pf	1023	11	'	'	POS
cord-256444-grw5s2pf	1023	12	UTR	UTR	NNP
cord-256444-grw5s2pf	1023	13	was	be	VBD
cord-256444-grw5s2pf	1023	14	selected	select	VBN
cord-256444-grw5s2pf	1023	15	during	during	IN
cord-256444-grw5s2pf	1023	16	persistent	persistent	JJ
cord-256444-grw5s2pf	1023	17	infection	infection	NN
cord-256444-grw5s2pf	1023	18	in	in	IN
cord-256444-grw5s2pf	1023	19	uitro	uitro	NNP
cord-256444-grw5s2pf	1023	20	(	(	-LRB-
cord-256444-grw5s2pf	1023	21	Chen	Chen	NNP
cord-256444-grw5s2pf	1023	22	and	and	CC
cord-256444-grw5s2pf	1023	23	Baric	Baric	NNP
cord-256444-grw5s2pf	1023	24	,	,	,
cord-256444-grw5s2pf	1023	25	1995	1995	CD
cord-256444-grw5s2pf	1023	26	)	)	-RRB-
cord-256444-grw5s2pf	1023	27	.	.	.
cord-256444-grw5s2pf	1024	1	This	this	DT
cord-256444-grw5s2pf	1024	2	mutant	mutant	NN
cord-256444-grw5s2pf	1024	3	had	have	VBD
cord-256444-grw5s2pf	1024	4	a	a	DT
cord-256444-grw5s2pf	1024	5	significantly	significantly	RB
cord-256444-grw5s2pf	1024	6	higher	high	JJR
cord-256444-grw5s2pf	1024	7	translation	translation	NN
cord-256444-grw5s2pf	1024	8	efficiency	efficiency	NN
cord-256444-grw5s2pf	1024	9	than	than	IN
cord-256444-grw5s2pf	1024	10	the	the	DT
cord-256444-grw5s2pf	1024	11	wild	wild	JJ
cord-256444-grw5s2pf	1024	12	-	-	HYPH
cord-256444-grw5s2pf	1024	13	type	type	NN
cord-256444-grw5s2pf	1024	14	virus	virus	NN
cord-256444-grw5s2pf	1024	15	.	.	.
cord-256444-grw5s2pf	1025	1	Different	different	JJ
cord-256444-grw5s2pf	1025	2	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	1026	1	mRNAs	mRNAs	NNP
cord-256444-grw5s2pf	1026	2	had	have	VBD
cord-256444-grw5s2pf	1026	3	5	5	CD
cord-256444-grw5s2pf	1026	4	'	'	''
cord-256444-grw5s2pf	1026	5	UTR	UTR	NNP
cord-256444-grw5s2pf	1026	6	of	of	IN
cord-256444-grw5s2pf	1026	7	various	various	JJ
cord-256444-grw5s2pf	1026	8	lengths	length	NNS
cord-256444-grw5s2pf	1026	9	,	,	,
cord-256444-grw5s2pf	1026	10	which	which	WDT
cord-256444-grw5s2pf	1026	11	may	may	MD
cord-256444-grw5s2pf	1026	12	also	also	RB
cord-256444-grw5s2pf	1026	13	affect	affect	VB
cord-256444-grw5s2pf	1026	14	their	-PRON-	PRP$
cord-256444-grw5s2pf	1026	15	translation	translation	NN
cord-256444-grw5s2pf	1026	16	.	.	.
cord-256444-grw5s2pf	1027	1	For	for	IN
cord-256444-grw5s2pf	1027	2	the	the	DT
cord-256444-grw5s2pf	1027	3	translation	translation	NN
cord-256444-grw5s2pf	1027	4	of	of	IN
cord-256444-grw5s2pf	1027	5	internal	internal	JJ
cord-256444-grw5s2pf	1027	6	ORFs	ORFs	NNP
cord-256444-grw5s2pf	1027	7	,	,	,
cord-256444-grw5s2pf	1027	8	several	several	JJ
cord-256444-grw5s2pf	1027	9	different	different	JJ
cord-256444-grw5s2pf	1027	10	mechanisms	mechanism	NNS
cord-256444-grw5s2pf	1027	11	are	be	VBP
cord-256444-grw5s2pf	1027	12	used	use	VBN
cord-256444-grw5s2pf	1027	13	by	by	IN
cord-256444-grw5s2pf	1027	14	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1027	15	:	:	:
cord-256444-grw5s2pf	1028	1	a.	a.	NN
cord-256444-grw5s2pf	1028	2	Ribosomal	Ribosomal	NNP
cord-256444-grw5s2pf	1028	3	Frameshifing	Frameshifing	NNP
cord-256444-grw5s2pf	1028	4	Within	within	IN
cord-256444-grw5s2pf	1028	5	the	the	DT
cord-256444-grw5s2pf	1028	6	Polymerase	Polymerase	NNP
cord-256444-grw5s2pf	1028	7	Gene	Gene	NNP
cord-256444-grw5s2pf	1028	8	.	.	.
cord-256444-grw5s2pf	1029	1	All	all	DT
cord-256444-grw5s2pf	1029	2	of	of	IN
cord-256444-grw5s2pf	1029	3	the	the	DT
cord-256444-grw5s2pf	1029	4	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1029	5	genes	gene	NNS
cord-256444-grw5s2pf	1029	6	1	1	CD
cord-256444-grw5s2pf	1029	7	(	(	-LRB-
cord-256444-grw5s2pf	1029	8	polymerase	polymerase	NN
cord-256444-grw5s2pf	1029	9	)	)	-RRB-
cord-256444-grw5s2pf	1029	10	sequenced	sequence	VBN
cord-256444-grw5s2pf	1029	11	so	so	RB
cord-256444-grw5s2pf	1029	12	far	far	RB
cord-256444-grw5s2pf	1029	13	contain	contain	VBP
cord-256444-grw5s2pf	1029	14	two	two	CD
cord-256444-grw5s2pf	1029	15	overlapping	overlap	VBG
cord-256444-grw5s2pf	1029	16	ORFs	orfs	NN
cord-256444-grw5s2pf	1029	17	.	.	.
cord-256444-grw5s2pf	1030	1	Several	several	JJ
cord-256444-grw5s2pf	1030	2	features	feature	NNS
cord-256444-grw5s2pf	1030	3	of	of	IN
cord-256444-grw5s2pf	1030	4	the	the	DT
cord-256444-grw5s2pf	1030	5	IBV	IBV	NNP
cord-256444-grw5s2pf	1030	6	polymerase	polymerase	NN
cord-256444-grw5s2pf	1030	7	gene	gene	NN
cord-256444-grw5s2pf	1030	8	sequence	sequence	NN
cord-256444-grw5s2pf	1030	9	,	,	,
cord-256444-grw5s2pf	1030	10	coupled	couple	VBN
cord-256444-grw5s2pf	1030	11	with	with	IN
cord-256444-grw5s2pf	1030	12	the	the	DT
cord-256444-grw5s2pf	1030	13	absence	absence	NN
cord-256444-grw5s2pf	1030	14	of	of	IN
cord-256444-grw5s2pf	1030	15	a	a	DT
cord-256444-grw5s2pf	1030	16	distinct	distinct	JJ
cord-256444-grw5s2pf	1030	17	mRNA	mrna	NN
cord-256444-grw5s2pf	1030	18	for	for	IN
cord-256444-grw5s2pf	1030	19	ORF	ORF	NNP
cord-256444-grw5s2pf	1030	20	lb	lb	NNP
cord-256444-grw5s2pf	1030	21	,	,	,
cord-256444-grw5s2pf	1030	22	suggested	suggest	VBD
cord-256444-grw5s2pf	1030	23	that	that	IN
cord-256444-grw5s2pf	1030	24	translation	translation	NN
cord-256444-grw5s2pf	1030	25	of	of	IN
cord-256444-grw5s2pf	1030	26	ORF	ORF	NNP
cord-256444-grw5s2pf	1030	27	l	l	NNP
cord-256444-grw5s2pf	1030	28	b	b	NNP
cord-256444-grw5s2pf	1030	29	involved	involve	VBD
cord-256444-grw5s2pf	1030	30	ribosomal	ribosomal	NN
cord-256444-grw5s2pf	1030	31	frameshifting	frameshifte	VBG
cord-256444-grw5s2pf	1030	32	from	from	IN
cord-256444-grw5s2pf	1030	33	ORF	ORF	NNP
cord-256444-grw5s2pf	1030	34	la	la	NNP
cord-256444-grw5s2pf	1030	35	,	,	,
cord-256444-grw5s2pf	1030	36	thus	thus	RB
cord-256444-grw5s2pf	1030	37	synthesizing	synthesize	VBG
cord-256444-grw5s2pf	1030	38	a	a	DT
cord-256444-grw5s2pf	1030	39	large	large	JJ
cord-256444-grw5s2pf	1030	40	polyprotein	polyprotein	NN
cord-256444-grw5s2pf	1030	41	containing	contain	VBG
cord-256444-grw5s2pf	1030	42	both	both	CC
cord-256444-grw5s2pf	1030	43	l	l	NNP
cord-256444-grw5s2pf	1030	44	a	a	NN
cord-256444-grw5s2pf	1030	45	and	and	CC
cord-256444-grw5s2pf	1030	46	l	l	NN
cord-256444-grw5s2pf	1030	47	b	b	NNP
cord-256444-grw5s2pf	1030	48	sequences	sequence	NNS
cord-256444-grw5s2pf	1030	49	.	.	.
cord-256444-grw5s2pf	1031	1	Subsequently	subsequently	RB
cord-256444-grw5s2pf	1031	2	,	,	,
cord-256444-grw5s2pf	1031	3	a	a	DT
cord-256444-grw5s2pf	1031	4	highly	highly	RB
cord-256444-grw5s2pf	1031	5	efficient	efficient	JJ
cord-256444-grw5s2pf	1031	6	(	(	-LRB-
cord-256444-grw5s2pf	1031	7	30	30	CD
cord-256444-grw5s2pf	1031	8	%	%	NN
cord-256444-grw5s2pf	1031	9	frequency	frequency	NN
cord-256444-grw5s2pf	1031	10	)	)	-RRB-
cord-256444-grw5s2pf	1031	11	-1	-1	.
cord-256444-grw5s2pf	1032	1	frameshift	frameshift	NN
cord-256444-grw5s2pf	1032	2	was	be	VBD
cord-256444-grw5s2pf	1032	3	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	1032	4	experimentally	experimentally	RB
cord-256444-grw5s2pf	1032	5	in	in	IN
cord-256444-grw5s2pf	1032	6	uitro	uitro	NNP
cord-256444-grw5s2pf	1032	7	(	(	-LRB-
cord-256444-grw5s2pf	1033	1	Brierley	Brierley	NNP
cord-256444-grw5s2pf	1033	2	et	et	NNP
cord-256444-grw5s2pf	1033	3	al	al	NNP
cord-256444-grw5s2pf	1033	4	.	.	.
cord-256444-grw5s2pf	1034	1	,	,	,
cord-256444-grw5s2pf	1034	2	1987	1987	CD
cord-256444-grw5s2pf	1034	3	;	;	:
cord-256444-grw5s2pf	1034	4	Somogyi	Somogyi	NNP
cord-256444-grw5s2pf	1034	5	et	et	NNP
cord-256444-grw5s2pf	1034	6	al	al	NNP
cord-256444-grw5s2pf	1034	7	.	.	NNP
cord-256444-grw5s2pf	1034	8	,	,	,
cord-256444-grw5s2pf	1034	9	1993	1993	CD
cord-256444-grw5s2pf	1034	10	)	)	-RRB-
cord-256444-grw5s2pf	1034	11	and	and	CC
cord-256444-grw5s2pf	1034	12	in	in	IN
cord-256444-grw5s2pf	1034	13	uiuo	uiuo	NN
cord-256444-grw5s2pf	1035	1	(	(	-LRB-
cord-256444-grw5s2pf	1035	2	Brierly	Brierly	NNP
cord-256444-grw5s2pf	1035	3	et	et	NNP
cord-256444-grw5s2pf	1035	4	al	al	NNP
cord-256444-grw5s2pf	1035	5	.	.	NNP
cord-256444-grw5s2pf	1035	6	,	,	,
cord-256444-grw5s2pf	1035	7	1990	1990	CD
cord-256444-grw5s2pf	1035	8	)	)	-RRB-
cord-256444-grw5s2pf	1035	9	.	.	.
cord-256444-grw5s2pf	1036	1	This	this	DT
cord-256444-grw5s2pf	1036	2	mechanism	mechanism	NN
cord-256444-grw5s2pf	1036	3	has	have	VBZ
cord-256444-grw5s2pf	1036	4	been	be	VBN
cord-256444-grw5s2pf	1036	5	shown	show	VBN
cord-256444-grw5s2pf	1036	6	to	to	TO
cord-256444-grw5s2pf	1036	7	operate	operate	VB
cord-256444-grw5s2pf	1036	8	in	in	IN
cord-256444-grw5s2pf	1036	9	gene	gene	NN
cord-256444-grw5s2pf	1036	10	1	1	CD
cord-256444-grw5s2pf	1036	11	of	of	IN
cord-256444-grw5s2pf	1036	12	MHV	MHV	NNP
cord-256444-grw5s2pf	1036	13	,	,	,
cord-256444-grw5s2pf	1036	14	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	1036	15	,	,	,
cord-256444-grw5s2pf	1036	16	and	and	CC
cord-256444-grw5s2pf	1036	17	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1036	18	as	as	RB
cord-256444-grw5s2pf	1036	19	well	well	RB
cord-256444-grw5s2pf	1037	1	(	(	-LRB-
cord-256444-grw5s2pf	1037	2	Bredenbeek	Bredenbeek	NNP
cord-256444-grw5s2pf	1037	3	et	et	NNP
cord-256444-grw5s2pf	1037	4	al	al	NNP
cord-256444-grw5s2pf	1037	5	.	.	NNP
cord-256444-grw5s2pf	1037	6	,	,	,
cord-256444-grw5s2pf	1037	7	1990	1990	CD
cord-256444-grw5s2pf	1037	8	;	;	:
cord-256444-grw5s2pf	1037	9	Lee	Lee	NNP
cord-256444-grw5s2pf	1037	10	et	et	NNP
cord-256444-grw5s2pf	1037	11	al	al	NNP
cord-256444-grw5s2pf	1037	12	.	.	NNP
cord-256444-grw5s2pf	1037	13	,	,	,
cord-256444-grw5s2pf	1037	14	1991	1991	CD
cord-256444-grw5s2pf	1037	15	;	;	:
cord-256444-grw5s2pf	1037	16	Eleouet	Eleouet	NNP
cord-256444-grw5s2pf	1037	17	et	et	NNP
cord-256444-grw5s2pf	1037	18	al	al	NNP
cord-256444-grw5s2pf	1037	19	.	.	NNP
cord-256444-grw5s2pf	1037	20	,	,	,
cord-256444-grw5s2pf	1037	21	1995	1995	CD
cord-256444-grw5s2pf	1037	22	)	)	-RRB-
cord-256444-grw5s2pf	1037	23	.	.	.
cord-256444-grw5s2pf	1038	1	In	in	IN
cord-256444-grw5s2pf	1038	2	all	all	DT
cord-256444-grw5s2pf	1038	3	cases	case	NNS
cord-256444-grw5s2pf	1038	4	,	,	,
cord-256444-grw5s2pf	1038	5	the	the	DT
cord-256444-grw5s2pf	1038	6	mechanism	mechanism	NN
cord-256444-grw5s2pf	1038	7	involves	involve	VBZ
cord-256444-grw5s2pf	1038	8	two	two	CD
cord-256444-grw5s2pf	1038	9	essential	essential	JJ
cord-256444-grw5s2pf	1038	10	elements	element	NNS
cord-256444-grw5s2pf	1038	11	:	:	:
cord-256444-grw5s2pf	1038	12	a	a	DT
cord-256444-grw5s2pf	1038	13	slippery	slippery	JJ
cord-256444-grw5s2pf	1038	14	site	site	NN
cord-256444-grw5s2pf	1038	15	followed	follow	VBN
cord-256444-grw5s2pf	1038	16	by	by	IN
cord-256444-grw5s2pf	1038	17	an	an	DT
cord-256444-grw5s2pf	1038	18	RNA	RNA	NNP
cord-256444-grw5s2pf	1038	19	pseudoknot	pseudoknot	NN
cord-256444-grw5s2pf	1038	20	(	(	-LRB-
cord-256444-grw5s2pf	1038	21	Brierley	Brierley	NNP
cord-256444-grw5s2pf	1038	22	et	et	NNP
cord-256444-grw5s2pf	1038	23	al	al	NNP
cord-256444-grw5s2pf	1038	24	.	.	NNP
cord-256444-grw5s2pf	1038	25	,	,	,
cord-256444-grw5s2pf	1038	26	1989	1989	CD
cord-256444-grw5s2pf	1038	27	)	)	-RRB-
cord-256444-grw5s2pf	1038	28	.	.	.
cord-256444-grw5s2pf	1039	1	The	the	DT
cord-256444-grw5s2pf	1039	2	site	site	NN
cord-256444-grw5s2pf	1039	3	at	at	IN
cord-256444-grw5s2pf	1039	4	which	which	WDT
cord-256444-grw5s2pf	1039	5	the	the	DT
cord-256444-grw5s2pf	1039	6	ribosome	ribosome	NN
cord-256444-grw5s2pf	1039	7	slips	slip	VBZ
cord-256444-grw5s2pf	1039	8	backward	backward	RB
cord-256444-grw5s2pf	1039	9	has	have	VBZ
cord-256444-grw5s2pf	1039	10	the	the	DT
cord-256444-grw5s2pf	1039	11	sequence	sequence	NN
cord-256444-grw5s2pf	1039	12	UUUAAAC	UUUAAAC	NNP
cord-256444-grw5s2pf	1039	13	.	.	.
cord-256444-grw5s2pf	1040	1	The	the	DT
cord-256444-grw5s2pf	1040	2	pseudoknots	pseudoknot	NNS
cord-256444-grw5s2pf	1040	3	of	of	IN
cord-256444-grw5s2pf	1040	4	IBV	IBV	NNP
cord-256444-grw5s2pf	1040	5	and	and	CC
cord-256444-grw5s2pf	1040	6	MHV	MHV	NNP
cord-256444-grw5s2pf	1040	7	are	be	VBP
cord-256444-grw5s2pf	1040	8	similar	similar	JJ
cord-256444-grw5s2pf	1040	9	,	,	,
cord-256444-grw5s2pf	1040	10	comprising	comprise	VBG
cord-256444-grw5s2pf	1040	11	two	two	CD
cord-256444-grw5s2pf	1040	12	base	base	NN
cord-256444-grw5s2pf	1040	13	-	-	HYPH
cord-256444-grw5s2pf	1040	14	paired	pair	VBN
cord-256444-grw5s2pf	1040	15	regions	region	NNS
cord-256444-grw5s2pf	1040	16	stacked	stack	VBN
cord-256444-grw5s2pf	1040	17	coaxially	coaxially	RB
cord-256444-grw5s2pf	1040	18	in	in	IN
cord-256444-grw5s2pf	1040	19	a	a	DT
cord-256444-grw5s2pf	1040	20	quasi	quasi	JJ
cord-256444-grw5s2pf	1040	21	-	-	JJ
cord-256444-grw5s2pf	1040	22	continuous	continuous	JJ
cord-256444-grw5s2pf	1040	23	manner	manner	NN
cord-256444-grw5s2pf	1040	24	and	and	CC
cord-256444-grw5s2pf	1040	25	connected	connect	VBN
cord-256444-grw5s2pf	1040	26	by	by	IN
cord-256444-grw5s2pf	1040	27	two	two	CD
cord-256444-grw5s2pf	1040	28	singlestrand	singlestrand	NN
cord-256444-grw5s2pf	1040	29	loop	loop	NN
cord-256444-grw5s2pf	1040	30	regions	region	NNS
cord-256444-grw5s2pf	1040	31	.	.	.
cord-256444-grw5s2pf	1041	1	The	the	DT
cord-256444-grw5s2pf	1041	2	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	1041	3	pseudoknot	pseudoknot	NN
cord-256444-grw5s2pf	1041	4	is	be	VBZ
cord-256444-grw5s2pf	1041	5	more	more	RBR
cord-256444-grw5s2pf	1041	6	complex	complex	JJ
cord-256444-grw5s2pf	1041	7	.	.	.
cord-256444-grw5s2pf	1042	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1042	2	is	be	VBZ
cord-256444-grw5s2pf	1042	3	the	the	DT
cord-256444-grw5s2pf	1042	4	overall	overall	JJ
cord-256444-grw5s2pf	1042	5	shape	shape	NN
cord-256444-grw5s2pf	1042	6	and	and	CC
cord-256444-grw5s2pf	1042	7	stability	stability	NN
cord-256444-grw5s2pf	1042	8	of	of	IN
cord-256444-grw5s2pf	1042	9	the	the	DT
cord-256444-grw5s2pf	1042	10	pseudoknot	pseudoknot	NN
cord-256444-grw5s2pf	1042	11	that	that	WDT
cord-256444-grw5s2pf	1042	12	are	be	VBP
cord-256444-grw5s2pf	1042	13	important	important	JJ
cord-256444-grw5s2pf	1042	14	,	,	,
cord-256444-grw5s2pf	1042	15	not	not	RB
cord-256444-grw5s2pf	1042	16	the	the	DT
cord-256444-grw5s2pf	1042	17	nucleotide	nucleotide	JJ
cord-256444-grw5s2pf	1042	18	sequence	sequence	NN
cord-256444-grw5s2pf	1042	19	per	per	FW
cord-256444-grw5s2pf	1042	20	se	se	FW
cord-256444-grw5s2pf	1042	21	.	.	.
cord-256444-grw5s2pf	1043	1	Two	two	CD
cord-256444-grw5s2pf	1043	2	reasons	reason	NNS
cord-256444-grw5s2pf	1043	3	have	have	VBP
cord-256444-grw5s2pf	1043	4	been	be	VBN
cord-256444-grw5s2pf	1043	5	put	put	VBN
cord-256444-grw5s2pf	1043	6	forward	forward	RB
cord-256444-grw5s2pf	1043	7	to	to	TO
cord-256444-grw5s2pf	1043	8	explain	explain	VB
cord-256444-grw5s2pf	1043	9	why	why	WRB
cord-256444-grw5s2pf	1043	10	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1043	11	should	should	MD
cord-256444-grw5s2pf	1043	12	employ	employ	VB
cord-256444-grw5s2pf	1043	13	ribosomal	ribosomal	JJ
cord-256444-grw5s2pf	1043	14	frameshifting	frameshifte	VBG
cord-256444-grw5s2pf	1043	15	to	to	TO
cord-256444-grw5s2pf	1043	16	translate	translate	VB
cord-256444-grw5s2pf	1043	17	ORF	ORF	NNP
cord-256444-grw5s2pf	1043	18	l	l	NN
cord-256444-grw5s2pf	1043	19	b	b	NNP
cord-256444-grw5s2pf	1043	20	(	(	-LRB-
cord-256444-grw5s2pf	1043	21	Brown	Brown	NNP
cord-256444-grw5s2pf	1043	22	and	and	CC
cord-256444-grw5s2pf	1043	23	Brierly	Brierly	NNP
cord-256444-grw5s2pf	1043	24	,	,	,
cord-256444-grw5s2pf	1043	25	1995	1995	CD
cord-256444-grw5s2pf	1043	26	)	)	-RRB-
cord-256444-grw5s2pf	1043	27	.	.	.
cord-256444-grw5s2pf	1044	1	One	one	CD
cord-256444-grw5s2pf	1044	2	reason	reason	NN
cord-256444-grw5s2pf	1044	3	is	be	VBZ
cord-256444-grw5s2pf	1044	4	that	that	IN
cord-256444-grw5s2pf	1044	5	this	this	DT
cord-256444-grw5s2pf	1044	6	is	be	VBZ
cord-256444-grw5s2pf	1044	7	done	do	VBN
cord-256444-grw5s2pf	1044	8	primarily	primarily	RB
cord-256444-grw5s2pf	1044	9	to	to	TO
cord-256444-grw5s2pf	1044	10	control	control	VB
cord-256444-grw5s2pf	1044	11	the	the	DT
cord-256444-grw5s2pf	1044	12	relative	relative	JJ
cord-256444-grw5s2pf	1044	13	amounts	amount	NNS
cord-256444-grw5s2pf	1044	14	of	of	IN
cord-256444-grw5s2pf	1044	15	the	the	DT
cord-256444-grw5s2pf	1044	16	l	l	NN
cord-256444-grw5s2pf	1045	1	a	a	LS
cord-256444-grw5s2pf	1045	2	and	and	CC
cord-256444-grw5s2pf	1045	3	l	l	NN
cord-256444-grw5s2pf	1045	4	b	b	NNP
cord-256444-grw5s2pf	1045	5	products	product	NNS
cord-256444-grw5s2pf	1045	6	.	.	.
cord-256444-grw5s2pf	1046	1	That	that	DT
cord-256444-grw5s2pf	1046	2	could	could	MD
cord-256444-grw5s2pf	1046	3	be	be	VB
cord-256444-grw5s2pf	1046	4	achieved	achieve	VBN
cord-256444-grw5s2pf	1046	5	in	in	IN
cord-256444-grw5s2pf	1046	6	other	other	JJ
cord-256444-grw5s2pf	1046	7	ways	way	NNS
cord-256444-grw5s2pf	1046	8	,	,	,
cord-256444-grw5s2pf	1046	9	of	of	IN
cord-256444-grw5s2pf	1046	10	course	course	NN
cord-256444-grw5s2pf	1046	11	,	,	,
cord-256444-grw5s2pf	1046	12	e.g.	e.g.	RB
cord-256444-grw5s2pf	1046	13	,	,	,
cord-256444-grw5s2pf	1046	14	by	by	IN
cord-256444-grw5s2pf	1046	15	translating	translate	VBG
cord-256444-grw5s2pf	1046	16	ORF	ORF	NNP
cord-256444-grw5s2pf	1046	17	l	l	NNP
cord-256444-grw5s2pf	1046	18	b	b	NNP
cord-256444-grw5s2pf	1046	19	from	from	IN
cord-256444-grw5s2pf	1046	20	a	a	DT
cord-256444-grw5s2pf	1046	21	separate	separate	JJ
cord-256444-grw5s2pf	1046	22	mRNA	mrna	NN
cord-256444-grw5s2pf	1046	23	,	,	,
cord-256444-grw5s2pf	1046	24	this	this	DT
cord-256444-grw5s2pf	1046	25	will	will	MD
cord-256444-grw5s2pf	1046	26	require	require	VB
cord-256444-grw5s2pf	1046	27	that	that	IN
cord-256444-grw5s2pf	1046	28	the	the	DT
cord-256444-grw5s2pf	1046	29	transcription	transcription	NN
cord-256444-grw5s2pf	1046	30	of	of	IN
cord-256444-grw5s2pf	1046	31	l	l	NNP
cord-256444-grw5s2pf	1046	32	a	a	NNP
cord-256444-grw5s2pf	1046	33	and	and	CC
cord-256444-grw5s2pf	1046	34	l	l	NN
cord-256444-grw5s2pf	1046	35	b	b	NNP
cord-256444-grw5s2pf	1046	36	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	1046	37	is	be	VBZ
cord-256444-grw5s2pf	1046	38	tightly	tightly	RB
cord-256444-grw5s2pf	1046	39	regulated	regulate	VBN
cord-256444-grw5s2pf	1046	40	.	.	.
cord-256444-grw5s2pf	1047	1	The	the	DT
cord-256444-grw5s2pf	1047	2	other	other	JJ
cord-256444-grw5s2pf	1047	3	reason	reason	NN
cord-256444-grw5s2pf	1047	4	may	may	MD
cord-256444-grw5s2pf	1047	5	be	be	VB
cord-256444-grw5s2pf	1047	6	to	to	TO
cord-256444-grw5s2pf	1047	7	avoid	avoid	VB
cord-256444-grw5s2pf	1047	8	making	make	VBG
cord-256444-grw5s2pf	1047	9	a	a	DT
cord-256444-grw5s2pf	1047	10	l	l	NN
cord-256444-grw5s2pf	1047	11	b	b	NNP
cord-256444-grw5s2pf	1047	12	mRNA	mrna	NN
cord-256444-grw5s2pf	1047	13	.	.	.
cord-256444-grw5s2pf	1048	1	Such	such	PDT
cord-256444-grw5s2pf	1048	2	an	an	DT
cord-256444-grw5s2pf	1048	3	mRNA	mrna	NN
cord-256444-grw5s2pf	1048	4	might	may	MD
cord-256444-grw5s2pf	1048	5	be	be	VB
cord-256444-grw5s2pf	1048	6	packaged	package	VBN
cord-256444-grw5s2pf	1048	7	into	into	IN
cord-256444-grw5s2pf	1048	8	virions	virion	NNS
cord-256444-grw5s2pf	1048	9	in	in	IN
cord-256444-grw5s2pf	1048	10	competition	competition	NN
cord-256444-grw5s2pf	1048	11	with	with	IN
cord-256444-grw5s2pf	1048	12	genomic	genomic	JJ
cord-256444-grw5s2pf	1048	13	RNA	RNA	NNP
cord-256444-grw5s2pf	1048	14	,	,	,
cord-256444-grw5s2pf	1048	15	as	as	IN
cord-256444-grw5s2pf	1048	16	the	the	DT
cord-256444-grw5s2pf	1048	17	RNA	RNA	NNP
cord-256444-grw5s2pf	1048	18	region	region	NN
cord-256444-grw5s2pf	1048	19	corresponding	correspond	VBG
cord-256444-grw5s2pf	1048	20	to	to	IN
cord-256444-grw5s2pf	1048	21	the	the	DT
cord-256444-grw5s2pf	1048	22	l	l	NNP
cord-256444-grw5s2pf	1048	23	b	b	NNP
cord-256444-grw5s2pf	1048	24	ORF	ORF	NNP
cord-256444-grw5s2pf	1048	25	of	of	IN
cord-256444-grw5s2pf	1048	26	MHV	MHV	NNP
cord-256444-grw5s2pf	1049	1	contains	contain	VBZ
cord-256444-grw5s2pf	1049	2	a	a	DT
cord-256444-grw5s2pf	1049	3	sequence	sequence	NN
cord-256444-grw5s2pf	1049	4	that	that	WDT
cord-256444-grw5s2pf	1049	5	is	be	VBZ
cord-256444-grw5s2pf	1049	6	essential	essential	JJ
cord-256444-grw5s2pf	1049	7	for	for	IN
cord-256444-grw5s2pf	1049	8	packaging	packaging	NN
cord-256444-grw5s2pf	1049	9	into	into	IN
cord-256444-grw5s2pf	1049	10	virions	virion	NNS
cord-256444-grw5s2pf	1049	11	(	(	-LRB-
cord-256444-grw5s2pf	1049	12	Fosmire	Fosmire	NNP
cord-256444-grw5s2pf	1049	13	et	et	NNP
cord-256444-grw5s2pf	1049	14	al	al	NNP
cord-256444-grw5s2pf	1049	15	.	.	NNP
cord-256444-grw5s2pf	1049	16	,	,	,
cord-256444-grw5s2pf	1049	17	1992	1992	CD
cord-256444-grw5s2pf	1049	18	)	)	-RRB-
cord-256444-grw5s2pf	1050	1	(	(	-LRB-
cord-256444-grw5s2pf	1050	2	see	see	VB
cord-256444-grw5s2pf	1050	3	Section	section	NN
cord-256444-grw5s2pf	1050	4	VI	VI	NNP
cord-256444-grw5s2pf	1050	5	,	,	,
cord-256444-grw5s2pf	1050	6	E	E	NNP
cord-256444-grw5s2pf	1050	7	,	,	,
cord-256444-grw5s2pf	1050	8	l	l	NN
cord-256444-grw5s2pf	1050	9	)	)	-RRB-
cord-256444-grw5s2pf	1050	10	.	.	.
cord-256444-grw5s2pf	1051	1	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1051	2	.	.	.
cord-256444-grw5s2pf	1052	1	The	the	DT
cord-256444-grw5s2pf	1052	2	E	e	NN
cord-256444-grw5s2pf	1052	3	proteins	protein	NNS
cord-256444-grw5s2pf	1052	4	of	of	IN
cord-256444-grw5s2pf	1052	5	IBV	IBV	NNP
cord-256444-grw5s2pf	1052	6	and	and	CC
cord-256444-grw5s2pf	1052	7	MHV	MHV	NNP
cord-256444-grw5s2pf	1052	8	are	be	VBP
cord-256444-grw5s2pf	1052	9	encoded	encode	VBN
cord-256444-grw5s2pf	1052	10	by	by	IN
cord-256444-grw5s2pf	1052	11	the	the	DT
cord-256444-grw5s2pf	1052	12	third	third	JJ
cord-256444-grw5s2pf	1052	13	and	and	CC
cord-256444-grw5s2pf	1052	14	second	second	JJ
cord-256444-grw5s2pf	1052	15	ORF	ORF	NNP
cord-256444-grw5s2pf	1052	16	,	,	,
cord-256444-grw5s2pf	1052	17	respectively	respectively	RB
cord-256444-grw5s2pf	1052	18	,	,	,
cord-256444-grw5s2pf	1052	19	of	of	IN
cord-256444-grw5s2pf	1052	20	the	the	DT
cord-256444-grw5s2pf	1052	21	corresponding	corresponding	JJ
cord-256444-grw5s2pf	1052	22	genes	gene	NNS
cord-256444-grw5s2pf	1052	23	3	3	CD
cord-256444-grw5s2pf	1052	24	and	and	CC
cord-256444-grw5s2pf	1052	25	5	5	CD
cord-256444-grw5s2pf	1053	1	(	(	-LRB-
cord-256444-grw5s2pf	1053	2	Fig	Fig	NNP
cord-256444-grw5s2pf	1053	3	,	,	,
cord-256444-grw5s2pf	1053	4	5	5	CD
cord-256444-grw5s2pf	1053	5	)	)	-RRB-
cord-256444-grw5s2pf	1053	6	.	.	.
cord-256444-grw5s2pf	1054	1	Cells	cell	NNS
cord-256444-grw5s2pf	1054	2	infected	infect	VBN
cord-256444-grw5s2pf	1054	3	with	with	IN
cord-256444-grw5s2pf	1054	4	IBV	IBV	NNP
cord-256444-grw5s2pf	1054	5	contain	contain	VBP
cord-256444-grw5s2pf	1054	6	the	the	DT
cord-256444-grw5s2pf	1054	7	products	product	NNS
cord-256444-grw5s2pf	1054	8	of	of	IN
cord-256444-grw5s2pf	1054	9	all	all	DT
cord-256444-grw5s2pf	1054	10	three	three	CD
cord-256444-grw5s2pf	1054	11	of	of	IN
cord-256444-grw5s2pf	1054	12	the	the	DT
cord-256444-grw5s2pf	1054	13	gene	gene	NN
cord-256444-grw5s2pf	1054	14	3	3	CD
cord-256444-grw5s2pf	1054	15	ORFs	ORFs	NNP
cord-256444-grw5s2pf	1054	16	(	(	-LRB-
cord-256444-grw5s2pf	1054	17	Liu	Liu	NNP
cord-256444-grw5s2pf	1054	18	et	et	NNP
cord-256444-grw5s2pf	1054	19	al	al	NNP
cord-256444-grw5s2pf	1054	20	.	.	NNP
cord-256444-grw5s2pf	1054	21	,	,	,
cord-256444-grw5s2pf	1054	22	1991	1991	CD
cord-256444-grw5s2pf	1054	23	)	)	-RRB-
cord-256444-grw5s2pf	1054	24	.	.	.
cord-256444-grw5s2pf	1055	1	Both	both	DT
cord-256444-grw5s2pf	1055	2	of	of	IN
cord-256444-grw5s2pf	1055	3	the	the	DT
cord-256444-grw5s2pf	1055	4	MHV	MHV	NNP
cord-256444-grw5s2pf	1055	5	gene	gene	NN
cord-256444-grw5s2pf	1055	6	5	5	CD
cord-256444-grw5s2pf	1055	7	ORFs	orf	NNS
cord-256444-grw5s2pf	1055	8	are	be	VBP
cord-256444-grw5s2pf	1055	9	translated	translate	VBN
cord-256444-grw5s2pf	1055	10	in	in	IN
cord-256444-grw5s2pf	1055	11	vitro	vitro	FW
cord-256444-grw5s2pf	1055	12	(	(	-LRB-
cord-256444-grw5s2pf	1055	13	Budzilowicz	Budzilowicz	NNP
cord-256444-grw5s2pf	1055	14	and	and	CC
cord-256444-grw5s2pf	1055	15	Weiss	Weiss	NNP
cord-256444-grw5s2pf	1055	16	,	,	,
cord-256444-grw5s2pf	1055	17	19871	19871	CD
cord-256444-grw5s2pf	1055	18	,	,	,
cord-256444-grw5s2pf	1055	19	but	but	CC
cord-256444-grw5s2pf	1055	20	only	only	RB
cord-256444-grw5s2pf	1055	21	the	the	DT
cord-256444-grw5s2pf	1055	22	5b	5b	CD
cord-256444-grw5s2pf	1055	23	ORF	ORF	NNP
cord-256444-grw5s2pf	1055	24	product	product	NN
cord-256444-grw5s2pf	1055	25	has	have	VBZ
cord-256444-grw5s2pf	1055	26	been	be	VBN
cord-256444-grw5s2pf	1055	27	detected	detect	VBN
cord-256444-grw5s2pf	1055	28	in	in	IN
cord-256444-grw5s2pf	1055	29	virus	virus	NN
cord-256444-grw5s2pf	1055	30	-	-	HYPH
cord-256444-grw5s2pf	1055	31	infected	infect	VBN
cord-256444-grw5s2pf	1055	32	cells	cell	NNS
cord-256444-grw5s2pf	1055	33	.	.	.
cord-256444-grw5s2pf	1056	1	Experiments	experiment	NNS
cord-256444-grw5s2pf	1056	2	have	have	VBP
cord-256444-grw5s2pf	1056	3	shown	show	VBN
cord-256444-grw5s2pf	1056	4	that	that	IN
cord-256444-grw5s2pf	1056	5	the	the	DT
cord-256444-grw5s2pf	1056	6	E	e	NN
cord-256444-grw5s2pf	1056	7	protein	protein	NN
cord-256444-grw5s2pf	1056	8	ORF	ORF	NNP
cord-256444-grw5s2pf	1056	9	of	of	IN
cord-256444-grw5s2pf	1056	10	both	both	CC
cord-256444-grw5s2pf	1056	11	IBV	IBV	NNP
cord-256444-grw5s2pf	1056	12	and	and	CC
cord-256444-grw5s2pf	1056	13	MHV	MHV	NNP
cord-256444-grw5s2pf	1056	14	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	1056	15	is	be	VBZ
cord-256444-grw5s2pf	1056	16	translated	translate	VBN
cord-256444-grw5s2pf	1056	17	by	by	IN
cord-256444-grw5s2pf	1056	18	a	a	DT
cord-256444-grw5s2pf	1056	19	cap	cap	NN
cord-256444-grw5s2pf	1056	20	-	-	HYPH
cord-256444-grw5s2pf	1056	21	independent	independent	JJ
cord-256444-grw5s2pf	1056	22	,	,	,
cord-256444-grw5s2pf	1056	23	internal	internal	JJ
cord-256444-grw5s2pf	1056	24	ribosomal	ribosomal	NN
cord-256444-grw5s2pf	1056	25	entry	entry	NN
cord-256444-grw5s2pf	1056	26	mechanism	mechanism	NN
cord-256444-grw5s2pf	1056	27	(	(	-LRB-
cord-256444-grw5s2pf	1056	28	Liu	Liu	NNP
cord-256444-grw5s2pf	1056	29	and	and	CC
cord-256444-grw5s2pf	1056	30	Inglis	Inglis	NNP
cord-256444-grw5s2pf	1056	31	,	,	,
cord-256444-grw5s2pf	1056	32	1992b	1992b	CD
cord-256444-grw5s2pf	1056	33	;	;	:
cord-256444-grw5s2pf	1056	34	Thiel	Thiel	NNP
cord-256444-grw5s2pf	1056	35	and	and	CC
cord-256444-grw5s2pf	1056	36	Siddell	Siddell	NNP
cord-256444-grw5s2pf	1056	37	,	,	,
cord-256444-grw5s2pf	1056	38	1994	1994	CD
cord-256444-grw5s2pf	1056	39	)	)	-RRB-
cord-256444-grw5s2pf	1056	40	.	.	.
cord-256444-grw5s2pf	1057	1	Furthermore	furthermore	RB
cord-256444-grw5s2pf	1057	2	,	,	,
cord-256444-grw5s2pf	1057	3	if	if	IN
cord-256444-grw5s2pf	1057	4	the	the	DT
cord-256444-grw5s2pf	1057	5	3a	3a	NNP
cord-256444-grw5s2pf	1057	6	and	and	CC
cord-256444-grw5s2pf	1057	7	3b	3b	NNP
cord-256444-grw5s2pf	1057	8	ORFs	ORFs	NNP
cord-256444-grw5s2pf	1057	9	were	be	VBD
cord-256444-grw5s2pf	1057	10	eliminated	eliminate	VBN
cord-256444-grw5s2pf	1057	11	from	from	IN
cord-256444-grw5s2pf	1057	12	the	the	DT
cord-256444-grw5s2pf	1057	13	IBV	IBV	NNP
cord-256444-grw5s2pf	1057	14	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1057	15	,	,	,
cord-256444-grw5s2pf	1057	16	translation	translation	NN
cord-256444-grw5s2pf	1057	17	of	of	IN
cord-256444-grw5s2pf	1057	18	the	the	DT
cord-256444-grw5s2pf	1057	19	3c	3c	NNP
cord-256444-grw5s2pf	1057	20	(	(	-LRB-
cord-256444-grw5s2pf	1057	21	E	E	NNP
cord-256444-grw5s2pf	1057	22	)	)	-RRB-
cord-256444-grw5s2pf	1057	23	ORF	ORF	NNP
cord-256444-grw5s2pf	1057	24	did	do	VBD
cord-256444-grw5s2pf	1057	25	not	not	RB
cord-256444-grw5s2pf	1057	26	occur	occur	VB
cord-256444-grw5s2pf	1057	27	(	(	-LRB-
cord-256444-grw5s2pf	1057	28	Liu	Liu	NNP
cord-256444-grw5s2pf	1057	29	and	and	CC
cord-256444-grw5s2pf	1057	30	Inglis	Inglis	NNP
cord-256444-grw5s2pf	1057	31	,	,	,
cord-256444-grw5s2pf	1057	32	1992b	1992b	CD
cord-256444-grw5s2pf	1057	33	)	)	-RRB-
cord-256444-grw5s2pf	1057	34	.	.	.
cord-256444-grw5s2pf	1058	1	This	this	DT
cord-256444-grw5s2pf	1058	2	suggested	suggest	VBD
cord-256444-grw5s2pf	1058	3	that	that	IN
cord-256444-grw5s2pf	1058	4	the	the	DT
cord-256444-grw5s2pf	1058	5	3d3b	3d3b	CD
cord-256444-grw5s2pf	1058	6	region	region	NN
cord-256444-grw5s2pf	1058	7	contains	contain	VBZ
cord-256444-grw5s2pf	1058	8	an	an	DT
cord-256444-grw5s2pf	1058	9	internal	internal	JJ
cord-256444-grw5s2pf	1058	10	ribosome	ribosome	NN
cord-256444-grw5s2pf	1058	11	entry	entry	NN
cord-256444-grw5s2pf	1058	12	site	site	NN
cord-256444-grw5s2pf	1058	13	(	(	-LRB-
cord-256444-grw5s2pf	1058	14	IRES	IRES	NNP
cord-256444-grw5s2pf	1058	15	)	)	-RRB-
cord-256444-grw5s2pf	1058	16	for	for	IN
cord-256444-grw5s2pf	1058	17	the	the	DT
cord-256444-grw5s2pf	1058	18	E	e	NN
cord-256444-grw5s2pf	1058	19	protein	protein	NN
cord-256444-grw5s2pf	1058	20	ORF	ORF	NNP
cord-256444-grw5s2pf	1058	21	.	.	.
cord-256444-grw5s2pf	1059	1	Le	Le	NNP
cord-256444-grw5s2pf	1059	2	and	and	CC
cord-256444-grw5s2pf	1059	3	colleagues	colleague	NNS
cord-256444-grw5s2pf	1059	4	have	have	VBP
cord-256444-grw5s2pf	1059	5	predicted	predict	VBN
cord-256444-grw5s2pf	1059	6	the	the	DT
cord-256444-grw5s2pf	1059	7	existence	existence	NN
cord-256444-grw5s2pf	1059	8	of	of	IN
cord-256444-grw5s2pf	1059	9	secondary	secondary	JJ
cord-256444-grw5s2pf	1059	10	structures	structure	NNS
cord-256444-grw5s2pf	1059	11	in	in	IN
cord-256444-grw5s2pf	1059	12	the	the	DT
cord-256444-grw5s2pf	1059	13	3d3b	3d3b	CD
cord-256444-grw5s2pf	1059	14	region	region	NN
cord-256444-grw5s2pf	1059	15	of	of	IN
cord-256444-grw5s2pf	1059	16	IBV	IBV	NNP
cord-256444-grw5s2pf	1059	17	which	which	WDT
cord-256444-grw5s2pf	1059	18	resemble	resemble	VBP
cord-256444-grw5s2pf	1059	19	the	the	DT
cord-256444-grw5s2pf	1059	20	IRES	ires	JJ
cord-256444-grw5s2pf	1059	21	elements	element	NNS
cord-256444-grw5s2pf	1059	22	of	of	IN
cord-256444-grw5s2pf	1059	23	picornaviruses	picornavirus	NNS
cord-256444-grw5s2pf	1059	24	(	(	-LRB-
cord-256444-grw5s2pf	1059	25	Le	Le	NNP
cord-256444-grw5s2pf	1059	26	et	et	FW
cord-256444-grw5s2pf	1059	27	al	al	NNP
cord-256444-grw5s2pf	1059	28	.	.	NNP
cord-256444-grw5s2pf	1059	29	,	,	,
cord-256444-grw5s2pf	1059	30	1994	1994	CD
cord-256444-grw5s2pf	1059	31	)	)	-RRB-
cord-256444-grw5s2pf	1059	32	.	.	.
cord-256444-grw5s2pf	1060	1	They	-PRON-	PRP
cord-256444-grw5s2pf	1060	2	predicted	predict	VBD
cord-256444-grw5s2pf	1060	3	a	a	DT
cord-256444-grw5s2pf	1060	4	265-nucleotide	265-nucleotide	CD
cord-256444-grw5s2pf	1060	5	sequence	sequence	NN
cord-256444-grw5s2pf	1060	6	in	in	IN
cord-256444-grw5s2pf	1060	7	3d3b	3d3b	CD
cord-256444-grw5s2pf	1060	8	which	which	WDT
cord-256444-grw5s2pf	1060	9	would	would	MD
cord-256444-grw5s2pf	1060	10	fold	fold	VB
cord-256444-grw5s2pf	1060	11	into	into	IN
cord-256444-grw5s2pf	1060	12	five	five	CD
cord-256444-grw5s2pf	1060	13	stem	stem	NN
cord-256444-grw5s2pf	1060	14	-	-	HYPH
cord-256444-grw5s2pf	1060	15	loops	loop	NNS
cord-256444-grw5s2pf	1060	16	,	,	,
cord-256444-grw5s2pf	1060	17	forming	form	VBG
cord-256444-grw5s2pf	1060	18	a	a	DT
cord-256444-grw5s2pf	1060	19	compact	compact	JJ
cord-256444-grw5s2pf	1060	20	structure	structure	NN
cord-256444-grw5s2pf	1060	21	by	by	IN
cord-256444-grw5s2pf	1060	22	the	the	DT
cord-256444-grw5s2pf	1060	23	interaction	interaction	NN
cord-256444-grw5s2pf	1060	24	of	of	IN
cord-256444-grw5s2pf	1060	25	two	two	CD
cord-256444-grw5s2pf	1060	26	pseudoknots	pseudoknot	NNS
cord-256444-grw5s2pf	1060	27	.	.	.
cord-256444-grw5s2pf	1061	1	c.	c.	NNP
cord-256444-grw5s2pf	1061	2	Translation	Translation	NNP
cord-256444-grw5s2pf	1061	3	of	of	IN
cord-256444-grw5s2pf	1061	4	Nonstructural	Nonstructural	NNP
cord-256444-grw5s2pf	1061	5	Proteins	protein	NNS
cord-256444-grw5s2pf	1061	6	.	.	.
cord-256444-grw5s2pf	1062	1	In	in	IN
cord-256444-grw5s2pf	1062	2	addition	addition	NN
cord-256444-grw5s2pf	1062	3	to	to	IN
cord-256444-grw5s2pf	1062	4	the	the	DT
cord-256444-grw5s2pf	1062	5	ns	ns	NNP
cord-256444-grw5s2pf	1062	6	proteins	protein	NNS
cord-256444-grw5s2pf	1062	7	encoded	encode	VBN
cord-256444-grw5s2pf	1062	8	from	from	IN
cord-256444-grw5s2pf	1062	9	the	the	DT
cord-256444-grw5s2pf	1062	10	5'-most	5'-most	CD
cord-256444-grw5s2pf	1062	11	ORFs	orfs	NN
cord-256444-grw5s2pf	1062	12	of	of	IN
cord-256444-grw5s2pf	1062	13	mRNAs	mrnas	CD
cord-256444-grw5s2pf	1062	14	,	,	,
cord-256444-grw5s2pf	1062	15	several	several	JJ
cord-256444-grw5s2pf	1062	16	other	other	JJ
cord-256444-grw5s2pf	1062	17	ns	ns	IN
cord-256444-grw5s2pf	1062	18	proteins	protein	NNS
cord-256444-grw5s2pf	1062	19	are	be	VBP
cord-256444-grw5s2pf	1062	20	encoded	encode	VBN
cord-256444-grw5s2pf	1062	21	from	from	IN
cord-256444-grw5s2pf	1062	22	an	an	DT
cord-256444-grw5s2pf	1062	23	internal	internal	JJ
cord-256444-grw5s2pf	1062	24	ORF	orf	NN
cord-256444-grw5s2pf	1062	25	of	of	IN
cord-256444-grw5s2pf	1062	26	some	some	DT
cord-256444-grw5s2pf	1062	27	viral	viral	JJ
cord-256444-grw5s2pf	1062	28	mRNAs	mrna	NNS
cord-256444-grw5s2pf	1062	29	,	,	,
cord-256444-grw5s2pf	1062	30	e.g.	e.g.	RB
cord-256444-grw5s2pf	1062	31	,	,	,
cord-256444-grw5s2pf	1062	32	3b	3b	CD
cord-256444-grw5s2pf	1062	33	of	of	IN
cord-256444-grw5s2pf	1062	34	IBV	IBV	NNP
cord-256444-grw5s2pf	1062	35	and	and	CC
cord-256444-grw5s2pf	1062	36	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	1062	37	,	,	,
cord-256444-grw5s2pf	1062	38	4b	4b	CD
cord-256444-grw5s2pf	1062	39	of	of	IN
cord-256444-grw5s2pf	1062	40	BCV	BCV	NNP
cord-256444-grw5s2pf	1062	41	,	,	,
cord-256444-grw5s2pf	1062	42	and	and	CC
cord-256444-grw5s2pf	1062	43	7b	7b	NN
cord-256444-grw5s2pf	1062	44	of	of	IN
cord-256444-grw5s2pf	1062	45	FCV	FCV	NNP
cord-256444-grw5s2pf	1062	46	(	(	-LRB-
cord-256444-grw5s2pf	1062	47	Fig	Fig	NNP
cord-256444-grw5s2pf	1062	48	.	.	NNP
cord-256444-grw5s2pf	1062	49	5	5	CD
cord-256444-grw5s2pf	1062	50	)	)	-RRB-
cord-256444-grw5s2pf	1062	51	.	.	.
cord-256444-grw5s2pf	1063	1	Most	Most	JJS
cord-256444-grw5s2pf	1063	2	of	of	IN
cord-256444-grw5s2pf	1063	3	these	these	DT
cord-256444-grw5s2pf	1063	4	products	product	NNS
cord-256444-grw5s2pf	1063	5	have	have	VBP
cord-256444-grw5s2pf	1063	6	been	be	VBN
cord-256444-grw5s2pf	1063	7	detected	detect	VBN
cord-256444-grw5s2pf	1063	8	in	in	IN
cord-256444-grw5s2pf	1063	9	virus	virus	NN
cord-256444-grw5s2pf	1063	10	-	-	HYPH
cord-256444-grw5s2pf	1063	11	infected	infect	VBN
cord-256444-grw5s2pf	1063	12	cells	cell	NNS
cord-256444-grw5s2pf	1063	13	;	;	:
cord-256444-grw5s2pf	1063	14	however	however	RB
cord-256444-grw5s2pf	1063	15	,	,	,
cord-256444-grw5s2pf	1063	16	the	the	DT
cord-256444-grw5s2pf	1063	17	mechanism	mechanism	NN
cord-256444-grw5s2pf	1063	18	of	of	IN
cord-256444-grw5s2pf	1063	19	the	the	DT
cord-256444-grw5s2pf	1063	20	internal	internal	JJ
cord-256444-grw5s2pf	1063	21	initiation	initiation	NN
cord-256444-grw5s2pf	1063	22	of	of	IN
cord-256444-grw5s2pf	1063	23	translation	translation	NN
cord-256444-grw5s2pf	1063	24	has	have	VBZ
cord-256444-grw5s2pf	1063	25	not	not	RB
cord-256444-grw5s2pf	1063	26	been	be	VBN
cord-256444-grw5s2pf	1063	27	elucidated	elucidate	VBN
cord-256444-grw5s2pf	1063	28	.	.	.
cord-256444-grw5s2pf	1064	1	BCV	BCV	NNP
cord-256444-grw5s2pf	1064	2	and	and	CC
cord-256444-grw5s2pf	1064	3	MHV	MHV	NNP
cord-256444-grw5s2pf	1064	4	RNA	RNA	NNP
cord-256444-grw5s2pf	1064	5	contains	contain	VBZ
cord-256444-grw5s2pf	1064	6	an	an	DT
cord-256444-grw5s2pf	1064	7	additional	additional	JJ
cord-256444-grw5s2pf	1064	8	internal	internal	JJ
cord-256444-grw5s2pf	1064	9	ORF	orf	NN
cord-256444-grw5s2pf	1064	10	within	within	IN
cord-256444-grw5s2pf	1064	11	the	the	DT
cord-256444-grw5s2pf	1064	12	N	N	NNP
cord-256444-grw5s2pf	1064	13	protein	protein	NN
cord-256444-grw5s2pf	1064	14	gene	gene	NN
cord-256444-grw5s2pf	1064	15	.	.	.
cord-256444-grw5s2pf	1065	1	This	this	DT
cord-256444-grw5s2pf	1065	2	ORF	ORF	NNP
cord-256444-grw5s2pf	1065	3	(	(	-LRB-
cord-256444-grw5s2pf	1065	4	termed	term	VBN
cord-256444-grw5s2pf	1065	5	I	i	NN
cord-256444-grw5s2pf	1065	6	)	)	-RRB-
cord-256444-grw5s2pf	1065	7	is	be	VBZ
cord-256444-grw5s2pf	1065	8	in	in	IN
cord-256444-grw5s2pf	1065	9	a	a	DT
cord-256444-grw5s2pf	1065	10	different	different	JJ
cord-256444-grw5s2pf	1065	11	reading	reading	NN
cord-256444-grw5s2pf	1065	12	frame	frame	NN
cord-256444-grw5s2pf	1065	13	from	from	IN
cord-256444-grw5s2pf	1065	14	that	that	DT
cord-256444-grw5s2pf	1065	15	of	of	IN
cord-256444-grw5s2pf	1065	16	N	n	CD
cord-256444-grw5s2pf	1065	17	protein	protein	NN
cord-256444-grw5s2pf	1065	18	and	and	CC
cord-256444-grw5s2pf	1065	19	encodes	encode	VBZ
cord-256444-grw5s2pf	1065	20	a	a	DT
cord-256444-grw5s2pf	1065	21	hydrophobic	hydrophobic	JJ
cord-256444-grw5s2pf	1065	22	protein	protein	NN
cord-256444-grw5s2pf	1065	23	(	(	-LRB-
cord-256444-grw5s2pf	1065	24	Senanayake	Senanayake	NNP
cord-256444-grw5s2pf	1065	25	et	et	FW
cord-256444-grw5s2pf	1065	26	al	al	NNP
cord-256444-grw5s2pf	1065	27	.	.	NNP
cord-256444-grw5s2pf	1065	28	,	,	,
cord-256444-grw5s2pf	1065	29	1992	1992	CD
cord-256444-grw5s2pf	1065	30	;	;	:
cord-256444-grw5s2pf	1065	31	Fischer	Fischer	NNP
cord-256444-grw5s2pf	1065	32	et	et	NNP
cord-256444-grw5s2pf	1065	33	al	al	NNP
cord-256444-grw5s2pf	1065	34	.	.	NNP
cord-256444-grw5s2pf	1065	35	,	,	,
cord-256444-grw5s2pf	1065	36	1997	1997	CD
cord-256444-grw5s2pf	1065	37	)	)	-RRB-
cord-256444-grw5s2pf	1065	38	.	.	.
cord-256444-grw5s2pf	1066	1	This	this	DT
cord-256444-grw5s2pf	1066	2	protein	protein	NN
cord-256444-grw5s2pf	1066	3	is	be	VBZ
cord-256444-grw5s2pf	1066	4	translated	translate	VBN
cord-256444-grw5s2pf	1066	5	in	in	IN
cord-256444-grw5s2pf	1066	6	virusinfected	virusinfected	JJ
cord-256444-grw5s2pf	1066	7	cells	cell	NNS
cord-256444-grw5s2pf	1066	8	by	by	IN
cord-256444-grw5s2pf	1066	9	a	a	DT
cord-256444-grw5s2pf	1066	10	leaky	leaky	JJ
cord-256444-grw5s2pf	1066	11	ribosomal	ribosomal	JJ
cord-256444-grw5s2pf	1066	12	scanning	scanning	NN
cord-256444-grw5s2pf	1066	13	mechanism	mechanism	NN
cord-256444-grw5s2pf	1066	14	from	from	IN
cord-256444-grw5s2pf	1066	15	the	the	DT
cord-256444-grw5s2pf	1066	16	bicistronic	bicistronic	NNP
cord-256444-grw5s2pf	1066	17	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1066	18	of	of	IN
cord-256444-grw5s2pf	1066	19	N	n	CD
cord-256444-grw5s2pf	1066	20	gene	gene	NN
cord-256444-grw5s2pf	1066	21	(	(	-LRB-
cord-256444-grw5s2pf	1066	22	Senanayake	Senanayake	NNP
cord-256444-grw5s2pf	1066	23	et	et	FW
cord-256444-grw5s2pf	1066	24	al	al	NNP
cord-256444-grw5s2pf	1066	25	.	.	NNP
cord-256444-grw5s2pf	1066	26	,	,	,
cord-256444-grw5s2pf	1066	27	1992	1992	CD
cord-256444-grw5s2pf	1066	28	)	)	-RRB-
cord-256444-grw5s2pf	1066	29	.	.	.
cord-256444-grw5s2pf	1067	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1067	2	is	be	VBZ
cord-256444-grw5s2pf	1067	3	a	a	DT
cord-256444-grw5s2pf	1067	4	nonessential	nonessential	JJ
cord-256444-grw5s2pf	1067	5	gene	gene	NN
cord-256444-grw5s2pf	1067	6	.	.	.
cord-256444-grw5s2pf	1068	1	The	the	DT
cord-256444-grw5s2pf	1068	2	mechanism	mechanism	NN
cord-256444-grw5s2pf	1068	3	of	of	IN
cord-256444-grw5s2pf	1068	4	its	-PRON-	PRP$
cord-256444-grw5s2pf	1068	5	regulation	regulation	NN
cord-256444-grw5s2pf	1068	6	is	be	VBZ
cord-256444-grw5s2pf	1068	7	not	not	RB
cord-256444-grw5s2pf	1068	8	yet	yet	RB
cord-256444-grw5s2pf	1068	9	clear	clear	JJ
cord-256444-grw5s2pf	1068	10	.	.	.
cord-256444-grw5s2pf	1069	1	The	the	DT
cord-256444-grw5s2pf	1069	2	gene	gene	NN
cord-256444-grw5s2pf	1069	3	1	1	CD
cord-256444-grw5s2pf	1069	4	product	product	NN
cord-256444-grw5s2pf	1069	5	is	be	VBZ
cord-256444-grw5s2pf	1069	6	predicted	predict	VBN
cord-256444-grw5s2pf	1069	7	to	to	TO
cord-256444-grw5s2pf	1069	8	be	be	VB
cord-256444-grw5s2pf	1069	9	nearly	nearly	RB
cord-256444-grw5s2pf	1069	10	700	700	CD
cord-256444-grw5s2pf	1069	11	-	-	HYPH
cord-256444-grw5s2pf	1069	12	800	800	CD
cord-256444-grw5s2pf	1069	13	kDa	kDa	NNS
cord-256444-grw5s2pf	1069	14	.	.	.
cord-256444-grw5s2pf	1070	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1070	2	is	be	VBZ
cord-256444-grw5s2pf	1070	3	probably	probably	RB
cord-256444-grw5s2pf	1070	4	processed	process	VBN
cord-256444-grw5s2pf	1070	5	into	into	IN
cord-256444-grw5s2pf	1070	6	multiple	multiple	JJ
cord-256444-grw5s2pf	1070	7	proteins	protein	NNS
cord-256444-grw5s2pf	1070	8	posttranslationally	posttranslationally	RB
cord-256444-grw5s2pf	1070	9	by	by	IN
cord-256444-grw5s2pf	1070	10	its	-PRON-	PRP$
cord-256444-grw5s2pf	1070	11	own	own	JJ
cord-256444-grw5s2pf	1070	12	proteases	protease	NNS
cord-256444-grw5s2pf	1070	13	.	.	.
cord-256444-grw5s2pf	1071	1	The	the	DT
cord-256444-grw5s2pf	1071	2	processing	processing	NN
cord-256444-grw5s2pf	1071	3	pathway	pathway	NN
cord-256444-grw5s2pf	1071	4	has	have	VBZ
cord-256444-grw5s2pf	1071	5	just	just	RB
cord-256444-grw5s2pf	1071	6	begun	begin	VBN
cord-256444-grw5s2pf	1071	7	to	to	TO
cord-256444-grw5s2pf	1071	8	be	be	VB
cord-256444-grw5s2pf	1071	9	explored	explore	VBN
cord-256444-grw5s2pf	1071	10	.	.	.
cord-256444-grw5s2pf	1072	1	Remarkably	remarkably	RB
cord-256444-grw5s2pf	1072	2	,	,	,
cord-256444-grw5s2pf	1072	3	the	the	DT
cord-256444-grw5s2pf	1072	4	protease	protease	NN
cord-256444-grw5s2pf	1072	5	domains	domain	NNS
cord-256444-grw5s2pf	1072	6	and	and	CC
cord-256444-grw5s2pf	1072	7	potential	potential	JJ
cord-256444-grw5s2pf	1072	8	cleavage	cleavage	NN
cord-256444-grw5s2pf	1072	9	sites	site	NNS
cord-256444-grw5s2pf	1072	10	predicted	predict	VBN
cord-256444-grw5s2pf	1072	11	by	by	IN
cord-256444-grw5s2pf	1072	12	computer	computer	NN
cord-256444-grw5s2pf	1072	13	analysis	analysis	NN
cord-256444-grw5s2pf	1073	1	(	(	-LRB-
cord-256444-grw5s2pf	1073	2	Gorbalenya	Gorbalenya	NNP
cord-256444-grw5s2pf	1073	3	et	et	NNP
cord-256444-grw5s2pf	1073	4	al	al	NNP
cord-256444-grw5s2pf	1073	5	.	.	NNP
cord-256444-grw5s2pf	1073	6	,	,	,
cord-256444-grw5s2pf	1073	7	198913	198913	CD
cord-256444-grw5s2pf	1073	8	;	;	:
cord-256444-grw5s2pf	1073	9	Lee	Lee	NNP
cord-256444-grw5s2pf	1073	10	et	et	NNP
cord-256444-grw5s2pf	1073	11	al	al	NNP
cord-256444-grw5s2pf	1073	12	.	.	NNP
cord-256444-grw5s2pf	1073	13	,	,	,
cord-256444-grw5s2pf	1073	14	1991	1991	CD
cord-256444-grw5s2pf	1073	15	)	)	-RRB-
cord-256444-grw5s2pf	1073	16	have	have	VBP
cord-256444-grw5s2pf	1073	17	largely	largely	RB
cord-256444-grw5s2pf	1073	18	been	be	VBN
cord-256444-grw5s2pf	1073	19	confirmed	confirm	VBN
cord-256444-grw5s2pf	1073	20	by	by	IN
cord-256444-grw5s2pf	1073	21	experimental	experimental	JJ
cord-256444-grw5s2pf	1073	22	data	datum	NNS
cord-256444-grw5s2pf	1073	23	.	.	.
cord-256444-grw5s2pf	1074	1	Initially	initially	RB
cord-256444-grw5s2pf	1074	2	,	,	,
cord-256444-grw5s2pf	1074	3	in	in	IN
cord-256444-grw5s2pf	1074	4	vitro	vitro	FW
cord-256444-grw5s2pf	1074	5	translation	translation	NN
cord-256444-grw5s2pf	1074	6	of	of	IN
cord-256444-grw5s2pf	1074	7	virion	virion	NN
cord-256444-grw5s2pf	1074	8	RNA	RNA	NNP
cord-256444-grw5s2pf	1074	9	of	of	IN
cord-256444-grw5s2pf	1074	10	MHV	MHV	NNP
cord-256444-grw5s2pf	1074	11	revealed	reveal	VBD
cord-256444-grw5s2pf	1074	12	several	several	JJ
cord-256444-grw5s2pf	1074	13	polypeptides	polypeptide	NNS
cord-256444-grw5s2pf	1074	14	of	of	IN
cord-256444-grw5s2pf	1074	15	more	more	JJR
cord-256444-grw5s2pf	1074	16	than	than	IN
cord-256444-grw5s2pf	1074	17	200	200	CD
cord-256444-grw5s2pf	1074	18	kDa	kDa	NNS
cord-256444-grw5s2pf	1074	19	(	(	-LRB-
cord-256444-grw5s2pf	1074	20	Leibowitz	Leibowitz	NNP
cord-256444-grw5s2pf	1074	21	et	et	NNP
cord-256444-grw5s2pf	1074	22	al	al	NNP
cord-256444-grw5s2pf	1074	23	.	.	NNP
cord-256444-grw5s2pf	1074	24	,	,	,
cord-256444-grw5s2pf	1074	25	1982b	1982b	CD
cord-256444-grw5s2pf	1074	26	;	;	:
cord-256444-grw5s2pf	1074	27	Denison	Denison	NNP
cord-256444-grw5s2pf	1074	28	and	and	CC
cord-256444-grw5s2pf	1074	29	Perlman	Perlman	NNP
cord-256444-grw5s2pf	1074	30	,	,	,
cord-256444-grw5s2pf	1074	31	1986	1986	CD
cord-256444-grw5s2pf	1074	32	)	)	-RRB-
cord-256444-grw5s2pf	1074	33	.	.	.
cord-256444-grw5s2pf	1075	1	In	in	IN
cord-256444-grw5s2pf	1075	2	addition	addition	NN
cord-256444-grw5s2pf	1075	3	,	,	,
cord-256444-grw5s2pf	1075	4	a	a	DT
cord-256444-grw5s2pf	1075	5	28-kDa	28-kda	CD
cord-256444-grw5s2pf	1075	6	product	product	NN
cord-256444-grw5s2pf	1075	7	was	be	VBD
cord-256444-grw5s2pf	1075	8	detected	detect	VBN
cord-256444-grw5s2pf	1075	9	and	and	CC
cord-256444-grw5s2pf	1075	10	shown	show	VBN
cord-256444-grw5s2pf	1075	11	to	to	TO
cord-256444-grw5s2pf	1075	12	have	have	VB
cord-256444-grw5s2pf	1075	13	originated	originate	VBN
cord-256444-grw5s2pf	1075	14	by	by	IN
cord-256444-grw5s2pf	1075	15	cleavage	cleavage	NN
cord-256444-grw5s2pf	1075	16	from	from	IN
cord-256444-grw5s2pf	1075	17	the	the	DT
cord-256444-grw5s2pf	1075	18	N	n	CD
cord-256444-grw5s2pf	1075	19	terminus	terminus	NN
cord-256444-grw5s2pf	1075	20	of	of	IN
cord-256444-grw5s2pf	1075	21	a	a	DT
cord-256444-grw5s2pf	1075	22	precursor	precursor	NN
cord-256444-grw5s2pf	1075	23	(	(	-LRB-
cord-256444-grw5s2pf	1075	24	Denison	Denison	NNP
cord-256444-grw5s2pf	1075	25	and	and	CC
cord-256444-grw5s2pf	1075	26	Perlman	Perlman	NNP
cord-256444-grw5s2pf	1075	27	1986	1986	CD
cord-256444-grw5s2pf	1075	28	;	;	:
cord-256444-grw5s2pf	1076	1	Soe	Soe	NNP
cord-256444-grw5s2pf	1076	2	et	et	FW
cord-256444-grw5s2pf	1076	3	al	al	NNP
cord-256444-grw5s2pf	1076	4	.	.	NNP
cord-256444-grw5s2pf	1076	5	,	,	,
cord-256444-grw5s2pf	1076	6	1987	1987	CD
cord-256444-grw5s2pf	1076	7	)	)	-RRB-
cord-256444-grw5s2pf	1076	8	,	,	,
cord-256444-grw5s2pf	1076	9	now	now	RB
cord-256444-grw5s2pf	1076	10	known	know	VBN
cord-256444-grw5s2pf	1076	11	to	to	TO
cord-256444-grw5s2pf	1076	12	be	be	VB
cord-256444-grw5s2pf	1076	13	the	the	DT
cord-256444-grw5s2pf	1076	14	beginning	beginning	NN
cord-256444-grw5s2pf	1076	15	of	of	IN
cord-256444-grw5s2pf	1076	16	the	the	DT
cord-256444-grw5s2pf	1076	17	ORF	ORF	NNP
cord-256444-grw5s2pf	1076	18	l	l	NNP
cord-256444-grw5s2pf	1076	19	a	a	DT
cord-256444-grw5s2pf	1076	20	polyprotein	polyprotein	NN
cord-256444-grw5s2pf	1076	21	(	(	-LRB-
cord-256444-grw5s2pf	1076	22	Fig	Fig	NNP
cord-256444-grw5s2pf	1076	23	.	.	.
cord-256444-grw5s2pf	1076	24	6	6	CD
cord-256444-grw5s2pf	1076	25	)	)	-RRB-
cord-256444-grw5s2pf	1076	26	.	.	.
cord-256444-grw5s2pf	1077	1	The	the	DT
cord-256444-grw5s2pf	1077	2	cleavage	cleavage	NN
cord-256444-grw5s2pf	1077	3	which	which	WDT
cord-256444-grw5s2pf	1077	4	generates	generate	VBZ
cord-256444-grw5s2pf	1077	5	p28	p28	NN
cord-256444-grw5s2pf	1077	6	is	be	VBZ
cord-256444-grw5s2pf	1077	7	carried	carry	VBN
cord-256444-grw5s2pf	1077	8	out	out	RP
cord-256444-grw5s2pf	1077	9	by	by	IN
cord-256444-grw5s2pf	1077	10	PLP	PLP	NNP
cord-256444-grw5s2pf	1077	11	1	1	CD
cord-256444-grw5s2pf	1078	1	(	(	-LRB-
cord-256444-grw5s2pf	1078	2	Fig	Fig	NNP
cord-256444-grw5s2pf	1078	3	.	.	.
cord-256444-grw5s2pf	1078	4	6	6	CD
cord-256444-grw5s2pf	1078	5	)	)	-RRB-
cord-256444-grw5s2pf	1078	6	.	.	.
cord-256444-grw5s2pf	1079	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1079	2	cleaves	cleave	VBZ
cord-256444-grw5s2pf	1079	3	between	between	IN
cord-256444-grw5s2pf	1079	4	residues	residue	NNS
cord-256444-grw5s2pf	1079	5	Gly-247	Gly-247	NNP
cord-256444-grw5s2pf	1079	6	and	and	CC
cord-256444-grw5s2pf	1079	7	Val-248	Val-248	NNP
cord-256444-grw5s2pf	1079	8	,	,	,
cord-256444-grw5s2pf	1079	9	mutation	mutation	NN
cord-256444-grw5s2pf	1079	10	of	of	IN
cord-256444-grw5s2pf	1079	11	either	either	CC
cord-256444-grw5s2pf	1079	12	residue	residue	NN
cord-256444-grw5s2pf	1079	13	resulting	result	VBG
cord-256444-grw5s2pf	1079	14	in	in	IN
cord-256444-grw5s2pf	1079	15	almost	almost	RB
cord-256444-grw5s2pf	1079	16	no	no	DT
cord-256444-grw5s2pf	1079	17	cleavage	cleavage	NN
cord-256444-grw5s2pf	1079	18	(	(	-LRB-
cord-256444-grw5s2pf	1079	19	Dong	Dong	NNP
cord-256444-grw5s2pf	1079	20	and	and	CC
cord-256444-grw5s2pf	1079	21	Baker	Baker	NNP
cord-256444-grw5s2pf	1079	22	,	,	,
cord-256444-grw5s2pf	1079	23	1994	1994	CD
cord-256444-grw5s2pf	1079	24	;	;	:
cord-256444-grw5s2pf	1079	25	Hughes	Hughes	NNP
cord-256444-grw5s2pf	1079	26	et	et	NNP
cord-256444-grw5s2pf	1079	27	al	al	NNP
cord-256444-grw5s2pf	1079	28	.	.	NNP
cord-256444-grw5s2pf	1079	29	,	,	,
cord-256444-grw5s2pf	1079	30	1995	1995	CD
cord-256444-grw5s2pf	1079	31	)	)	-RRB-
cord-256444-grw5s2pf	1079	32	.	.	.
cord-256444-grw5s2pf	1080	1	In	in	IN
cord-256444-grw5s2pf	1080	2	addition	addition	NN
cord-256444-grw5s2pf	1080	3	to	to	IN
cord-256444-grw5s2pf	1080	4	p28	p28	CD
cord-256444-grw5s2pf	1080	5	,	,	,
cord-256444-grw5s2pf	1080	6	the	the	DT
cord-256444-grw5s2pf	1080	7	MHV	MHV	NNP
cord-256444-grw5s2pf	1080	8	ORF	ORF	NNP
cord-256444-grw5s2pf	1080	9	l	l	NNP
cord-256444-grw5s2pf	1080	10	a	a	NNP
cord-256444-grw5s2pf	1080	11	encodes	encode	VBZ
cord-256444-grw5s2pf	1080	12	a	a	DT
cord-256444-grw5s2pf	1080	13	protein	protein	NN
cord-256444-grw5s2pf	1080	14	of	of	IN
cord-256444-grw5s2pf	1080	15	more	more	JJR
cord-256444-grw5s2pf	1080	16	than	than	IN
cord-256444-grw5s2pf	1080	17	400	400	CD
cord-256444-grw5s2pf	1080	18	kDa	kDa	NNS
cord-256444-grw5s2pf	1080	19	,	,	,
cord-256444-grw5s2pf	1080	20	which	which	WDT
cord-256444-grw5s2pf	1080	21	is	be	VBZ
cord-256444-grw5s2pf	1080	22	cleaved	cleave	VBN
cord-256444-grw5s2pf	1080	23	to	to	IN
cord-256444-grw5s2pf	1080	24	a	a	DT
cord-256444-grw5s2pf	1080	25	290-kDa	290-kda	CD
cord-256444-grw5s2pf	1080	26	product	product	NN
cord-256444-grw5s2pf	1080	27	,	,	,
cord-256444-grw5s2pf	1080	28	which	which	WDT
cord-256444-grw5s2pf	1080	29	,	,	,
cord-256444-grw5s2pf	1080	30	in	in	IN
cord-256444-grw5s2pf	1080	31	turn	turn	NN
cord-256444-grw5s2pf	1080	32	,	,	,
cord-256444-grw5s2pf	1080	33	is	be	VBZ
cord-256444-grw5s2pf	1080	34	cleaved	cleave	VBN
cord-256444-grw5s2pf	1080	35	to	to	TO
cord-256444-grw5s2pf	1080	36	produce	produce	VB
cord-256444-grw5s2pf	1080	37	a	a	DT
cord-256444-grw5s2pf	1080	38	50-kDa	50-kda	CD
cord-256444-grw5s2pf	1080	39	and	and	CC
cord-256444-grw5s2pf	1080	40	a	a	DT
cord-256444-grw5s2pf	1080	41	240-kDa	240-kda	CD
cord-256444-grw5s2pf	1080	42	product	product	NN
cord-256444-grw5s2pf	1080	43	(	(	-LRB-
cord-256444-grw5s2pf	1080	44	Denison	Denison	NNP
cord-256444-grw5s2pf	1080	45	et	et	NNP
cord-256444-grw5s2pf	1080	46	al	al	NNP
cord-256444-grw5s2pf	1080	47	.	.	NNP
cord-256444-grw5s2pf	1080	48	,	,	,
cord-256444-grw5s2pf	1080	49	1992	1992	CD
cord-256444-grw5s2pf	1080	50	)	)	-RRB-
cord-256444-grw5s2pf	1081	1	(	(	-LRB-
cord-256444-grw5s2pf	1081	2	Fig	Fig	NNP
cord-256444-grw5s2pf	1081	3	.	.	.
cord-256444-grw5s2pf	1081	4	6	6	CD
cord-256444-grw5s2pf	1081	5	)	)	-RRB-
cord-256444-grw5s2pf	1081	6	.	.	.
cord-256444-grw5s2pf	1082	1	Another	another	DT
cord-256444-grw5s2pf	1082	2	protein	protein	NN
cord-256444-grw5s2pf	1082	3	of	of	IN
cord-256444-grw5s2pf	1082	4	65	65	CD
cord-256444-grw5s2pf	1082	5	kDa	kDa	NNP
cord-256444-grw5s2pf	1082	6	is	be	VBZ
cord-256444-grw5s2pf	1082	7	derived	derive	VBN
cord-256444-grw5s2pf	1082	8	from	from	IN
cord-256444-grw5s2pf	1082	9	sequence	sequence	NN
cord-256444-grw5s2pf	1082	10	immediately	immediately	RB
cord-256444-grw5s2pf	1082	11	downstream	downstream	RB
cord-256444-grw5s2pf	1082	12	of	of	IN
cord-256444-grw5s2pf	1082	13	the	the	DT
cord-256444-grw5s2pf	1082	14	p28-encoding	p28-encoding	NN
cord-256444-grw5s2pf	1082	15	region	region	NN
cord-256444-grw5s2pf	1082	16	,	,	,
cord-256444-grw5s2pf	1082	17	thus	thus	RB
cord-256444-grw5s2pf	1082	18	representing	represent	VBG
cord-256444-grw5s2pf	1082	19	the	the	DT
cord-256444-grw5s2pf	1082	20	N	n	CD
cord-256444-grw5s2pf	1082	21	-	-	HYPH
cord-256444-grw5s2pf	1082	22	terminal	terminal	JJ
cord-256444-grw5s2pf	1082	23	part	part	NN
cord-256444-grw5s2pf	1082	24	of	of	IN
cord-256444-grw5s2pf	1082	25	the	the	DT
cord-256444-grw5s2pf	1082	26	large	large	JJ
cord-256444-grw5s2pf	1082	27	polyprotein	polyprotein	NN
cord-256444-grw5s2pf	1082	28	initially	initially	RB
cord-256444-grw5s2pf	1082	29	found	find	VBD
cord-256444-grw5s2pf	1082	30	in	in	RP
cord-256444-grw5s2pf	1082	31	in	in	IN
cord-256444-grw5s2pf	1082	32	uitro	uitro	NNP
cord-256444-grw5s2pf	1082	33	translation	translation	NN
cord-256444-grw5s2pf	1082	34	(	(	-LRB-
cord-256444-grw5s2pf	1082	35	probably	probably	RB
cord-256444-grw5s2pf	1082	36	more	more	JJR
cord-256444-grw5s2pf	1082	37	than	than	IN
cord-256444-grw5s2pf	1082	38	400	400	CD
cord-256444-grw5s2pf	1082	39	kDa	kDa	NNS
cord-256444-grw5s2pf	1082	40	)	)	-RRB-
cord-256444-grw5s2pf	1083	1	(	(	-LRB-
cord-256444-grw5s2pf	1083	2	Fig	Fig	NNP
cord-256444-grw5s2pf	1083	3	.	.	.
cord-256444-grw5s2pf	1083	4	 	 	_SP
cord-256444-grw5s2pf	1083	5	6	6	CD
cord-256444-grw5s2pf	1083	6	)	)	-RRB-
cord-256444-grw5s2pf	1083	7	.	.	.
cord-256444-grw5s2pf	1084	1	The	the	DT
cord-256444-grw5s2pf	1084	2	cleavage	cleavage	NN
cord-256444-grw5s2pf	1084	3	of	of	IN
cord-256444-grw5s2pf	1084	4	p65	p65	NN
cord-256444-grw5s2pf	1084	5	from	from	IN
cord-256444-grw5s2pf	1084	6	the	the	DT
cord-256444-grw5s2pf	1084	7	polyprotein	polyprotein	NN
cord-256444-grw5s2pf	1084	8	was	be	VBD
cord-256444-grw5s2pf	1084	9	also	also	RB
cord-256444-grw5s2pf	1084	10	carried	carry	VBN
cord-256444-grw5s2pf	1084	11	out	out	RP
cord-256444-grw5s2pf	1084	12	by	by	IN
cord-256444-grw5s2pf	1084	13	PLPl	PLPl	NNS
cord-256444-grw5s2pf	1084	14	(	(	-LRB-
cord-256444-grw5s2pf	1084	15	Bonilla	Bonilla	NNP
cord-256444-grw5s2pf	1084	16	et	et	NNP
cord-256444-grw5s2pf	1084	17	al	al	NNP
cord-256444-grw5s2pf	1084	18	.	.	NNP
cord-256444-grw5s2pf	1084	19	,	,	,
cord-256444-grw5s2pf	1084	20	,	,	,
cord-256444-grw5s2pf	1084	21	1997	1997	CD
cord-256444-grw5s2pf	1084	22	.	.	.
cord-256444-grw5s2pf	1085	1	Inhibition	inhibition	NN
cord-256444-grw5s2pf	1085	2	of	of	IN
cord-256444-grw5s2pf	1085	3	the	the	DT
cord-256444-grw5s2pf	1085	4	C	c	NN
cord-256444-grw5s2pf	1085	5	-	-	HYPH
cord-256444-grw5s2pf	1085	6	terminal	terminal	NN
cord-256444-grw5s2pf	1085	7	cleavage	cleavage	NN
cord-256444-grw5s2pf	1085	8	of	of	IN
cord-256444-grw5s2pf	1085	9	p65	p65	NN
cord-256444-grw5s2pf	1085	10	by	by	IN
cord-256444-grw5s2pf	1085	11	E64d	E64d	NNS
cord-256444-grw5s2pf	1085	12	,	,	,
cord-256444-grw5s2pf	1085	13	an	an	DT
cord-256444-grw5s2pf	1085	14	irreversible	irreversible	JJ
cord-256444-grw5s2pf	1085	15	inhibitor	inhibitor	NN
cord-256444-grw5s2pf	1085	16	of	of	IN
cord-256444-grw5s2pf	1085	17	cysteine	cysteine	NN
cord-256444-grw5s2pf	1085	18	(	(	-LRB-
cord-256444-grw5s2pf	1085	19	thio	thio	NNP
cord-256444-grw5s2pf	1085	20	)	)	-RRB-
cord-256444-grw5s2pf	1085	21	proteinases	proteinases	NNP
cord-256444-grw5s2pf	1085	22	,	,	,
cord-256444-grw5s2pf	1085	23	inhibited	inhibit	VBD
cord-256444-grw5s2pf	1085	24	MHV	MHV	NNP
cord-256444-grw5s2pf	1085	25	replication	replication	NN
cord-256444-grw5s2pf	1085	26	.	.	.
cord-256444-grw5s2pf	1086	1	In	in	IN
cord-256444-grw5s2pf	1086	2	addition	addition	NN
cord-256444-grw5s2pf	1086	3	,	,	,
cord-256444-grw5s2pf	1086	4	the	the	DT
cord-256444-grw5s2pf	1086	5	3CLP	3clp	CD
cord-256444-grw5s2pf	1086	6	domain	domain	NN
cord-256444-grw5s2pf	1086	7	is	be	VBZ
cord-256444-grw5s2pf	1086	8	cleaved	cleave	VBN
cord-256444-grw5s2pf	1086	9	from	from	IN
cord-256444-grw5s2pf	1086	10	the	the	DT
cord-256444-grw5s2pf	1086	11	polyprotein	polyprotein	NN
cord-256444-grw5s2pf	1086	12	by	by	IN
cord-256444-grw5s2pf	1086	13	the	the	DT
cord-256444-grw5s2pf	1086	14	autocatalytic	autocatalytic	JJ
cord-256444-grw5s2pf	1086	15	cleavage	cleavage	NN
cord-256444-grw5s2pf	1086	16	activity	activity	NN
cord-256444-grw5s2pf	1086	17	of	of	IN
cord-256444-grw5s2pf	1086	18	3CLP	3clp	DT
cord-256444-grw5s2pf	1086	19	itself	-PRON-	PRP
cord-256444-grw5s2pf	1086	20	to	to	TO
cord-256444-grw5s2pf	1086	21	generate	generate	VB
cord-256444-grw5s2pf	1086	22	a	a	DT
cord-256444-grw5s2pf	1086	23	27	27	CD
cord-256444-grw5s2pf	1086	24	-	-	SYM
cord-256444-grw5s2pf	1086	25	34	34	CD
cord-256444-grw5s2pf	1086	26	kDa	kDa	NNP
cord-256444-grw5s2pf	1086	27	protein	protein	NN
cord-256444-grw5s2pf	1086	28	,	,	,
cord-256444-grw5s2pf	1086	29	which	which	WDT
cord-256444-grw5s2pf	1086	30	contains	contain	VBZ
cord-256444-grw5s2pf	1086	31	both	both	CC
cord-256444-grw5s2pf	1086	32	the	the	DT
cord-256444-grw5s2pf	1086	33	trans	trans	NNP
cord-256444-grw5s2pf	1086	34	-	-	HYPH
cord-256444-grw5s2pf	1086	35	and	and	CC
cord-256444-grw5s2pf	1086	36	cis	cis	NNP
cord-256444-grw5s2pf	1086	37	-	-	HYPH
cord-256444-grw5s2pf	1086	38	acting	act	VBG
cord-256444-grw5s2pf	1086	39	proteolytic	proteolytic	JJ
cord-256444-grw5s2pf	1086	40	activities	activity	NNS
cord-256444-grw5s2pf	1086	41	(	(	-LRB-
cord-256444-grw5s2pf	1086	42	Lu	Lu	NNP
cord-256444-grw5s2pf	1086	43	et	et	FW
cord-256444-grw5s2pf	1086	44	al	al	NNP
cord-256444-grw5s2pf	1086	45	.	.	NNP
cord-256444-grw5s2pf	1086	46	,	,	,
cord-256444-grw5s2pf	1086	47	,	,	,
cord-256444-grw5s2pf	1086	48	1996	1996	CD
cord-256444-grw5s2pf	1086	49	Liu	Liu	NNP
cord-256444-grw5s2pf	1086	50	and	and	CC
cord-256444-grw5s2pf	1086	51	Brown	Brown	NNP
cord-256444-grw5s2pf	1086	52	,	,	,
cord-256444-grw5s2pf	1086	53	1994	1994	CD
cord-256444-grw5s2pf	1086	54	;	;	:
cord-256444-grw5s2pf	1086	55	Ziebuhr	Ziebuhr	NNP
cord-256444-grw5s2pf	1086	56	et	et	NNP
cord-256444-grw5s2pf	1086	57	al	al	NNP
cord-256444-grw5s2pf	1086	58	.	.	NNP
cord-256444-grw5s2pf	1086	59	,	,	,
cord-256444-grw5s2pf	1086	60	1995	1995	CD
cord-256444-grw5s2pf	1086	61	)	)	-RRB-
cord-256444-grw5s2pf	1086	62	.	.	.
cord-256444-grw5s2pf	1087	1	E64d	E64d	NNP
cord-256444-grw5s2pf	1087	2	also	also	RB
cord-256444-grw5s2pf	1087	3	inhibited	inhibit	VBD
cord-256444-grw5s2pf	1087	4	the	the	DT
cord-256444-grw5s2pf	1087	5	3CLP	3clp	CD
cord-256444-grw5s2pf	1087	6	protease	protease	NN
cord-256444-grw5s2pf	1087	7	activity	activity	NN
cord-256444-grw5s2pf	1087	8	.	.	.
cord-256444-grw5s2pf	1088	1	The	the	DT
cord-256444-grw5s2pf	1088	2	processing	processing	NN
cord-256444-grw5s2pf	1088	3	pathway	pathway	NN
cord-256444-grw5s2pf	1088	4	of	of	IN
cord-256444-grw5s2pf	1088	5	the	the	DT
cord-256444-grw5s2pf	1088	6	l	l	NNP
cord-256444-grw5s2pf	1088	7	b	b	NNP
cord-256444-grw5s2pf	1088	8	protein	protein	NN
cord-256444-grw5s2pf	1088	9	sequence	sequence	NN
cord-256444-grw5s2pf	1088	10	is	be	VBZ
cord-256444-grw5s2pf	1088	11	less	less	RBR
cord-256444-grw5s2pf	1088	12	clear	clear	JJ
cord-256444-grw5s2pf	1088	13	.	.	.
cord-256444-grw5s2pf	1089	1	There	there	EX
cord-256444-grw5s2pf	1089	2	is	be	VBZ
cord-256444-grw5s2pf	1089	3	experimental	experimental	JJ
cord-256444-grw5s2pf	1089	4	evidence	evidence	NN
cord-256444-grw5s2pf	1089	5	with	with	IN
cord-256444-grw5s2pf	1089	6	IBV	IBV	NNP
cord-256444-grw5s2pf	1089	7	and	and	CC
cord-256444-grw5s2pf	1089	8	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	1089	9	that	that	IN
cord-256444-grw5s2pf	1089	10	the	the	DT
cord-256444-grw5s2pf	1089	11	l	l	NNP
cord-256444-grw5s2pf	1089	12	b	b	NNP
cord-256444-grw5s2pf	1089	13	polyprotein	polyprotein	NNP
cord-256444-grw5s2pf	1089	14	is	be	VBZ
cord-256444-grw5s2pf	1089	15	cleaved	cleave	VBN
cord-256444-grw5s2pf	1089	16	in	in	IN
cord-256444-grw5s2pf	1089	17	trans	trans	NNP
cord-256444-grw5s2pf	1089	18	by	by	IN
cord-256444-grw5s2pf	1089	19	the	the	DT
cord-256444-grw5s2pf	1089	20	3CLP	3clp	CD
cord-256444-grw5s2pf	1089	21	encoded	encode	VBN
cord-256444-grw5s2pf	1089	22	by	by	IN
cord-256444-grw5s2pf	1090	1	ORF	ORF	NNP
cord-256444-grw5s2pf	1090	2	l	l	NNP
cord-256444-grw5s2pf	1090	3	a	a	NN
cord-256444-grw5s2pf	1091	1	(	(	-LRB-
cord-256444-grw5s2pf	1091	2	Liu	Liu	NNP
cord-256444-grw5s2pf	1091	3	et	et	NNP
cord-256444-grw5s2pf	1091	4	al	al	NNP
cord-256444-grw5s2pf	1091	5	.	.	.
cord-256444-grw5s2pf	1092	1	,	,	,
cord-256444-grw5s2pf	1092	2	1994	1994	CD
cord-256444-grw5s2pf	1092	3	;	;	:
cord-256444-grw5s2pf	1092	4	Ziebuhr	Ziebuhr	NNP
cord-256444-grw5s2pf	1092	5	et	et	NNP
cord-256444-grw5s2pf	1092	6	al	al	NNP
cord-256444-grw5s2pf	1092	7	.	.	.
cord-256444-grw5s2pf	1093	1	,	,	,
cord-256444-grw5s2pf	1093	2	1995	1995	CD
cord-256444-grw5s2pf	1093	3	;	;	:
cord-256444-grw5s2pf	1093	4	Grotzinger	Grotzinger	NNP
cord-256444-grw5s2pf	1093	5	et	et	NNP
cord-256444-grw5s2pf	1093	6	al	al	NNP
cord-256444-grw5s2pf	1093	7	.	.	NNP
cord-256444-grw5s2pf	1093	8	,	,	,
cord-256444-grw5s2pf	1093	9	1996	1996	CD
cord-256444-grw5s2pf	1093	10	)	)	-RRB-
cord-256444-grw5s2pf	1093	11	.	.	.
cord-256444-grw5s2pf	1094	1	A	a	DT
cord-256444-grw5s2pf	1094	2	polypeptide	polypeptide	NN
cord-256444-grw5s2pf	1094	3	of	of	IN
cord-256444-grw5s2pf	1094	4	approximately	approximately	RB
cord-256444-grw5s2pf	1094	5	100	100	CD
cord-256444-grw5s2pf	1094	6	kDa	kDa	NNS
cord-256444-grw5s2pf	1094	7	,	,	,
cord-256444-grw5s2pf	1094	8	representing	represent	VBG
cord-256444-grw5s2pf	1094	9	the	the	DT
cord-256444-grw5s2pf	1094	10	extreme	extreme	JJ
cord-256444-grw5s2pf	1094	11	C	C	NNP
cord-256444-grw5s2pf	1094	12	terminus	terminus	NN
cord-256444-grw5s2pf	1094	13	of	of	IN
cord-256444-grw5s2pf	1094	14	ORF	ORF	NNP
cord-256444-grw5s2pf	1094	15	l	l	NNP
cord-256444-grw5s2pf	1094	16	a	a	NNP
cord-256444-grw5s2pf	1094	17	and	and	CC
cord-256444-grw5s2pf	1094	18	the	the	DT
cord-256444-grw5s2pf	1094	19	N	n	CD
cord-256444-grw5s2pf	1094	20	terminus	terminus	NN
cord-256444-grw5s2pf	1094	21	of	of	IN
cord-256444-grw5s2pf	1094	22	the	the	DT
cord-256444-grw5s2pf	1094	23	frame	frame	NN
cord-256444-grw5s2pf	1094	24	shifted	shift	VBD
cord-256444-grw5s2pf	1094	25	ORF	ORF	NNP
cord-256444-grw5s2pf	1094	26	lb	lb	NN
cord-256444-grw5s2pf	1094	27	,	,	,
cord-256444-grw5s2pf	1094	28	was	be	VBD
cord-256444-grw5s2pf	1094	29	immunoprecipitated	immunoprecipitate	VBN
cord-256444-grw5s2pf	1094	30	from	from	IN
cord-256444-grw5s2pf	1094	31	IBV	IBV	NNP
cord-256444-grw5s2pf	1094	32	-	-	HYPH
cord-256444-grw5s2pf	1094	33	infected	infect	VBN
cord-256444-grw5s2pf	1094	34	cells	cell	NNS
cord-256444-grw5s2pf	1094	35	.	.	.
cord-256444-grw5s2pf	1095	1	The	the	DT
cord-256444-grw5s2pf	1095	2	cleavage	cleavage	NN
cord-256444-grw5s2pf	1095	3	sites	site	NNS
cord-256444-grw5s2pf	1095	4	of	of	IN
cord-256444-grw5s2pf	1095	5	the	the	DT
cord-256444-grw5s2pf	1095	6	100-kDa	100-kda	CD
cord-256444-grw5s2pf	1095	7	protein	protein	NN
cord-256444-grw5s2pf	1095	8	appear	appear	VBP
cord-256444-grw5s2pf	1095	9	to	to	TO
cord-256444-grw5s2pf	1095	10	be	be	VB
cord-256444-grw5s2pf	1095	11	at	at	IN
cord-256444-grw5s2pf	1095	12	the	the	DT
cord-256444-grw5s2pf	1095	13	Q	Q	NNP
cord-256444-grw5s2pf	1095	14	/	/	SYM
cord-256444-grw5s2pf	1095	15	S	s	NN
cord-256444-grw5s2pf	1095	16	sites	site	NNS
cord-256444-grw5s2pf	1095	17	,	,	,
cord-256444-grw5s2pf	1095	18	as	as	IN
cord-256444-grw5s2pf	1095	19	predicted	predict	VBN
cord-256444-grw5s2pf	1095	20	from	from	IN
cord-256444-grw5s2pf	1095	21	the	the	DT
cord-256444-grw5s2pf	1095	22	computer	computer	NN
cord-256444-grw5s2pf	1095	23	analysis	analysis	NN
cord-256444-grw5s2pf	1095	24	and	and	CC
cord-256444-grw5s2pf	1095	25	consistent	consistent	JJ
cord-256444-grw5s2pf	1095	26	with	with	IN
cord-256444-grw5s2pf	1095	27	the	the	DT
cord-256444-grw5s2pf	1095	28	known	know	VBN
cord-256444-grw5s2pf	1095	29	substrate	substrate	NN
cord-256444-grw5s2pf	1095	30	specificity	specificity	NN
cord-256444-grw5s2pf	1095	31	of	of	IN
cord-256444-grw5s2pf	1095	32	the	the	DT
cord-256444-grw5s2pf	1095	33	picornavirus	picornavirus	NNP
cord-256444-grw5s2pf	1095	34	3C	3C	NNP
cord-256444-grw5s2pf	1095	35	protease	protease	NNP
cord-256444-grw5s2pf	1095	36	.	.	.
cord-256444-grw5s2pf	1096	1	A	a	DT
cord-256444-grw5s2pf	1096	2	similar	similar	JJ
cord-256444-grw5s2pf	1096	3	observation	observation	NN
cord-256444-grw5s2pf	1096	4	was	be	VBD
cord-256444-grw5s2pf	1096	5	recently	recently	RB
cord-256444-grw5s2pf	1096	6	made	make	VBN
cord-256444-grw5s2pf	1096	7	with	with	IN
cord-256444-grw5s2pf	1096	8	HCV-229E	HCV-229E	NNP
cord-256444-grw5s2pf	1096	9	(	(	-LRB-
cord-256444-grw5s2pf	1096	10	Grotzinger	Grotzinger	NNP
cord-256444-grw5s2pf	1096	11	et	et	NNP
cord-256444-grw5s2pf	1096	12	al	al	NNP
cord-256444-grw5s2pf	1096	13	.	.	NNP
cord-256444-grw5s2pf	1096	14	,	,	,
cord-256444-grw5s2pf	1096	15	1996	1996	CD
cord-256444-grw5s2pf	1096	16	)	)	-RRB-
cord-256444-grw5s2pf	1096	17	.	.	.
cord-256444-grw5s2pf	1097	1	This	this	DT
cord-256444-grw5s2pf	1097	2	100-kDa	100-kda	CD
cord-256444-grw5s2pf	1097	3	protein	protein	NN
cord-256444-grw5s2pf	1097	4	contains	contain	VBZ
cord-256444-grw5s2pf	1097	5	the	the	DT
cord-256444-grw5s2pf	1097	6	putative	putative	JJ
cord-256444-grw5s2pf	1097	7	RNA	RNA	NNP
cord-256444-grw5s2pf	1097	8	polymerase	polymerase	NN
cord-256444-grw5s2pf	1097	9	motif	motif	NN
cord-256444-grw5s2pf	1097	10	and	and	CC
cord-256444-grw5s2pf	1097	11	thus	thus	RB
cord-256444-grw5s2pf	1097	12	may	may	MD
cord-256444-grw5s2pf	1097	13	represent	represent	VB
cord-256444-grw5s2pf	1097	14	the	the	DT
cord-256444-grw5s2pf	1097	15	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1097	16	polymerase	polymerase	NN
cord-256444-grw5s2pf	1097	17	.	.	.
cord-256444-grw5s2pf	1098	1	The	the	DT
cord-256444-grw5s2pf	1098	2	coding	code	VBG
cord-256444-grw5s2pf	1098	3	region	region	NN
cord-256444-grw5s2pf	1098	4	for	for	IN
cord-256444-grw5s2pf	1098	5	this	this	DT
cord-256444-grw5s2pf	1098	6	protein	protein	NN
cord-256444-grw5s2pf	1098	7	belongs	belong	VBZ
cord-256444-grw5s2pf	1098	8	to	to	IN
cord-256444-grw5s2pf	1098	9	complementation	complementation	NN
cord-256444-grw5s2pf	1098	10	group	group	NN
cord-256444-grw5s2pf	1098	11	D	D	NNP
cord-256444-grw5s2pf	1098	12	,	,	,
cord-256444-grw5s2pf	1098	13	which	which	WDT
cord-256444-grw5s2pf	1098	14	has	have	VBZ
cord-256444-grw5s2pf	1098	15	been	be	VBN
cord-256444-grw5s2pf	1098	16	shown	show	VBN
cord-256444-grw5s2pf	1098	17	to	to	TO
cord-256444-grw5s2pf	1098	18	effect	effect	VB
cord-256444-grw5s2pf	1098	19	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1098	20	transcription	transcription	NN
cord-256444-grw5s2pf	1098	21	(	(	-LRB-
cord-256444-grw5s2pf	1098	22	Fig	Fig	NNP
cord-256444-grw5s2pf	1098	23	.	.	.
cord-256444-grw5s2pf	1098	24	6	6	CD
cord-256444-grw5s2pf	1098	25	)	)	-RRB-
cord-256444-grw5s2pf	1098	26	.	.	.
cord-256444-grw5s2pf	1099	1	b.	b.	NNP
cord-256444-grw5s2pf	1099	2	Processing	Processing	NNP
cord-256444-grw5s2pf	1099	3	of	of	IN
cord-256444-grw5s2pf	1099	4	the	the	DT
cord-256444-grw5s2pf	1099	5	Structural	structural	JJ
cord-256444-grw5s2pf	1099	6	Proteins	protein	NNS
cord-256444-grw5s2pf	1100	1	The	the	DT
cord-256444-grw5s2pf	1100	2	S	S	NNP
cord-256444-grw5s2pf	1100	3	protein	protein	NN
cord-256444-grw5s2pf	1100	4	is	be	VBZ
cord-256444-grw5s2pf	1100	5	co	co	NN
cord-256444-grw5s2pf	1100	6	-	-	NN
cord-256444-grw5s2pf	1100	7	translationally	translationally	RB
cord-256444-grw5s2pf	1100	8	glycosylated	glycosylate	VBN
cord-256444-grw5s2pf	1100	9	with	with	IN
cord-256444-grw5s2pf	1100	10	Nlinked	Nlinked	NNP
cord-256444-grw5s2pf	1100	11	glycans	glycan	NNS
cord-256444-grw5s2pf	1100	12	.	.	.
cord-256444-grw5s2pf	1101	1	Conversion	conversion	NN
cord-256444-grw5s2pf	1101	2	of	of	IN
cord-256444-grw5s2pf	1101	3	the	the	DT
cord-256444-grw5s2pf	1101	4	high	high	JJ
cord-256444-grw5s2pf	1101	5	mannose	mannose	NN
cord-256444-grw5s2pf	1101	6	(	(	-LRB-
cord-256444-grw5s2pf	1101	7	simple	simple	JJ
cord-256444-grw5s2pf	1101	8	)	)	-RRB-
cord-256444-grw5s2pf	1101	9	glycans	glycan	NNS
cord-256444-grw5s2pf	1101	10	of	of	IN
cord-256444-grw5s2pf	1101	11	the	the	DT
cord-256444-grw5s2pf	1101	12	S	S	NNP
cord-256444-grw5s2pf	1101	13	protein	protein	NN
cord-256444-grw5s2pf	1101	14	to	to	IN
cord-256444-grw5s2pf	1101	15	complex	complex	JJ
cord-256444-grw5s2pf	1101	16	ones	one	NNS
cord-256444-grw5s2pf	1101	17	is	be	VBZ
cord-256444-grw5s2pf	1101	18	a	a	DT
cord-256444-grw5s2pf	1101	19	slow	slow	JJ
cord-256444-grw5s2pf	1101	20	process	process	NN
cord-256444-grw5s2pf	1101	21	,	,	,
cord-256444-grw5s2pf	1101	22	the	the	DT
cord-256444-grw5s2pf	1101	23	half	half	JJ
cord-256444-grw5s2pf	1101	24	-	-	HYPH
cord-256444-grw5s2pf	1101	25	life	life	NN
cord-256444-grw5s2pf	1101	26	being	be	VBG
cord-256444-grw5s2pf	1101	27	one	one	CD
cord-256444-grw5s2pf	1101	28	to	to	IN
cord-256444-grw5s2pf	1101	29	several	several	JJ
cord-256444-grw5s2pf	1101	30	hours	hour	NNS
cord-256444-grw5s2pf	1102	1	(	(	-LRB-
cord-256444-grw5s2pf	1102	2	Vennema	Vennema	NNP
cord-256444-grw5s2pf	1102	3	et	et	FW
cord-256444-grw5s2pf	1102	4	al	al	NNP
cord-256444-grw5s2pf	1102	5	.	.	NNP
cord-256444-grw5s2pf	1102	6	,	,	,
cord-256444-grw5s2pf	1102	7	1990a	1990a	CD
cord-256444-grw5s2pf	1102	8	)	)	-RRB-
cord-256444-grw5s2pf	1102	9	.	.	.
cord-256444-grw5s2pf	1103	1	The	the	DT
cord-256444-grw5s2pf	1103	2	S	S	NNP
cord-256444-grw5s2pf	1103	3	protein	protein	NN
cord-256444-grw5s2pf	1103	4	undergoes	undergo	VBZ
cord-256444-grw5s2pf	1103	5	multiple	multiple	JJ
cord-256444-grw5s2pf	1103	6	disulfide	disulfide	JJ
cord-256444-grw5s2pf	1103	7	linkages	linkage	NNS
cord-256444-grw5s2pf	1103	8	to	to	TO
cord-256444-grw5s2pf	1103	9	fold	fold	VB
cord-256444-grw5s2pf	1103	10	into	into	IN
cord-256444-grw5s2pf	1103	11	a	a	DT
cord-256444-grw5s2pf	1103	12	more	more	RBR
cord-256444-grw5s2pf	1103	13	complex	complex	JJ
cord-256444-grw5s2pf	1103	14	structure	structure	NN
cord-256444-grw5s2pf	1103	15	(	(	-LRB-
cord-256444-grw5s2pf	1103	16	Opstelten	Opstelten	NNP
cord-256444-grw5s2pf	1103	17	et	et	NNP
cord-256444-grw5s2pf	1103	18	al	al	NNP
cord-256444-grw5s2pf	1103	19	.	.	NNP
cord-256444-grw5s2pf	1103	20	,	,	,
cord-256444-grw5s2pf	1103	21	1993	1993	CD
cord-256444-grw5s2pf	1103	22	)	)	-RRB-
cord-256444-grw5s2pf	1103	23	and	and	CC
cord-256444-grw5s2pf	1103	24	oligomerize	oligomerize	NNP
cord-256444-grw5s2pf	1103	25	into	into	IN
cord-256444-grw5s2pf	1103	26	a	a	DT
cord-256444-grw5s2pf	1103	27	trimer	trimer	NN
cord-256444-grw5s2pf	1103	28	in	in	IN
cord-256444-grw5s2pf	1103	29	the	the	DT
cord-256444-grw5s2pf	1103	30	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1103	31	complex	complex	NN
cord-256444-grw5s2pf	1103	32	(	(	-LRB-
cord-256444-grw5s2pf	1103	33	Delmas	Delmas	NNP
cord-256444-grw5s2pf	1103	34	and	and	CC
cord-256444-grw5s2pf	1103	35	Laude	Laude	NNP
cord-256444-grw5s2pf	1103	36	,	,	,
cord-256444-grw5s2pf	1103	37	1990	1990	CD
cord-256444-grw5s2pf	1103	38	)	)	-RRB-
cord-256444-grw5s2pf	1103	39	.	.	.
cord-256444-grw5s2pf	1104	1	The	the	DT
cord-256444-grw5s2pf	1104	2	S	S	NNP
cord-256444-grw5s2pf	1104	3	prepropolypeptide	prepropolypeptide	NN
cord-256444-grw5s2pf	1104	4	is	be	VBZ
cord-256444-grw5s2pf	1104	5	converted	convert	VBN
cord-256444-grw5s2pf	1104	6	to	to	IN
cord-256444-grw5s2pf	1104	7	a	a	DT
cord-256444-grw5s2pf	1104	8	propolypeptide	propolypeptide	NN
cord-256444-grw5s2pf	1104	9	by	by	IN
cord-256444-grw5s2pf	1104	10	removal	removal	NN
cord-256444-grw5s2pf	1104	11	of	of	IN
cord-256444-grw5s2pf	1104	12	the	the	DT
cord-256444-grw5s2pf	1104	13	N	n	CD
cord-256444-grw5s2pf	1104	14	-	-	HYPH
cord-256444-grw5s2pf	1104	15	terminal	terminal	NN
cord-256444-grw5s2pf	1104	16	signal	signal	NN
cord-256444-grw5s2pf	1104	17	peptide	peptide	NN
cord-256444-grw5s2pf	1104	18	.	.	.
cord-256444-grw5s2pf	1105	1	Whether	whether	IN
cord-256444-grw5s2pf	1105	2	the	the	DT
cord-256444-grw5s2pf	1105	3	propolypeptide	propolypeptide	NN
cord-256444-grw5s2pf	1105	4	is	be	VBZ
cord-256444-grw5s2pf	1105	5	cleaved	cleave	VBN
cord-256444-grw5s2pf	1105	6	to	to	TO
cord-256444-grw5s2pf	1105	7	generate	generate	VB
cord-256444-grw5s2pf	1105	8	S1	S1	NNP
cord-256444-grw5s2pf	1105	9	and	and	CC
cord-256444-grw5s2pf	1105	10	S2	S2	NNP
cord-256444-grw5s2pf	1105	11	depends	depend	VBZ
cord-256444-grw5s2pf	1105	12	on	on	IN
cord-256444-grw5s2pf	1105	13	the	the	DT
cord-256444-grw5s2pf	1105	14	virus	virus	NN
cord-256444-grw5s2pf	1105	15	species	species	NN
cord-256444-grw5s2pf	1105	16	and	and	CC
cord-256444-grw5s2pf	1105	17	strain	strain	NN
cord-256444-grw5s2pf	1105	18	and	and	CC
cord-256444-grw5s2pf	1105	19	,	,	,
cord-256444-grw5s2pf	1105	20	to	to	IN
cord-256444-grw5s2pf	1105	21	some	some	DT
cord-256444-grw5s2pf	1105	22	extent	extent	NN
cord-256444-grw5s2pf	1105	23	,	,	,
cord-256444-grw5s2pf	1105	24	on	on	IN
cord-256444-grw5s2pf	1105	25	the	the	DT
cord-256444-grw5s2pf	1105	26	cell	cell	NN
cord-256444-grw5s2pf	1105	27	type	type	NN
cord-256444-grw5s2pf	1105	28	in	in	IN
cord-256444-grw5s2pf	1105	29	which	which	WDT
cord-256444-grw5s2pf	1105	30	the	the	DT
cord-256444-grw5s2pf	1105	31	virus	virus	NN
cord-256444-grw5s2pf	1105	32	is	be	VBZ
cord-256444-grw5s2pf	1105	33	grown	grow	VBN
cord-256444-grw5s2pf	1105	34	(	(	-LRB-
cord-256444-grw5s2pf	1105	35	Frana	Frana	NNP
cord-256444-grw5s2pf	1105	36	et	et	FW
cord-256444-grw5s2pf	1105	37	al	al	NNP
cord-256444-grw5s2pf	1105	38	.	.	NNP
cord-256444-grw5s2pf	1105	39	,	,	,
cord-256444-grw5s2pf	1105	40	1985	1985	CD
cord-256444-grw5s2pf	1105	41	)	)	-RRB-
cord-256444-grw5s2pf	1105	42	.	.	.
cord-256444-grw5s2pf	1106	1	The	the	DT
cord-256444-grw5s2pf	1106	2	Sl	Sl	NNP
cord-256444-grw5s2pf	1106	3	-	-	HYPH
cord-256444-grw5s2pf	1106	4	S2	s2	NN
cord-256444-grw5s2pf	1106	5	cleavage	cleavage	NN
cord-256444-grw5s2pf	1106	6	site	site	NN
cord-256444-grw5s2pf	1106	7	in	in	IN
cord-256444-grw5s2pf	1106	8	IBV	IBV	NNP
cord-256444-grw5s2pf	1106	9	and	and	CC
cord-256444-grw5s2pf	1106	10	MHV	MHV	NNP
cord-256444-grw5s2pf	1106	11	is	be	VBZ
cord-256444-grw5s2pf	1106	12	adjacent	adjacent	JJ
cord-256444-grw5s2pf	1106	13	to	to	IN
cord-256444-grw5s2pf	1106	14	several	several	JJ
cord-256444-grw5s2pf	1106	15	basic	basic	JJ
cord-256444-grw5s2pf	1106	16	residues	residue	NNS
cord-256444-grw5s2pf	1106	17	(	(	-LRB-
cord-256444-grw5s2pf	1106	18	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	1106	19	et	et	NNP
cord-256444-grw5s2pf	1106	20	al	al	NNP
cord-256444-grw5s2pf	1106	21	.	.	NNP
cord-256444-grw5s2pf	1106	22	,	,	,
cord-256444-grw5s2pf	1106	23	1986a	1986a	CD
cord-256444-grw5s2pf	1106	24	;	;	:
cord-256444-grw5s2pf	1106	25	Luytjes	Luytjes	NNP
cord-256444-grw5s2pf	1106	26	et	et	NNP
cord-256444-grw5s2pf	1106	27	al	al	NNP
cord-256444-grw5s2pf	1106	28	.	.	NNP
cord-256444-grw5s2pf	1106	29	,	,	,
cord-256444-grw5s2pf	1106	30	1987	1987	CD
cord-256444-grw5s2pf	1106	31	)	)	-RRB-
cord-256444-grw5s2pf	1106	32	.	.	.
cord-256444-grw5s2pf	1107	1	Those	those	DT
cord-256444-grw5s2pf	1107	2	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1107	3	whose	whose	WP$
cord-256444-grw5s2pf	1107	4	S	s	NN
cord-256444-grw5s2pf	1107	5	protein	protein	NN
cord-256444-grw5s2pf	1107	6	is	be	VBZ
cord-256444-grw5s2pf	1107	7	not	not	RB
cord-256444-grw5s2pf	1107	8	cleaved	cleave	VBN
cord-256444-grw5s2pf	1107	9	,	,	,
cord-256444-grw5s2pf	1107	10	e.g.	e.g.	RB
cord-256444-grw5s2pf	1107	11	,	,	,
cord-256444-grw5s2pf	1107	12	FCV	FCV	NNP
cord-256444-grw5s2pf	1107	13	,	,	,
cord-256444-grw5s2pf	1107	14	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1107	15	,	,	,
cord-256444-grw5s2pf	1107	16	and	and	CC
cord-256444-grw5s2pf	1107	17	CCV	CCV	NNP
cord-256444-grw5s2pf	1107	18	,	,	,
cord-256444-grw5s2pf	1107	19	have	have	VBP
cord-256444-grw5s2pf	1107	20	no	no	DT
cord-256444-grw5s2pf	1107	21	such	such	JJ
cord-256444-grw5s2pf	1107	22	pairs	pair	NNS
cord-256444-grw5s2pf	1107	23	of	of	IN
cord-256444-grw5s2pf	1107	24	basic	basic	JJ
cord-256444-grw5s2pf	1107	25	residues	residue	NNS
cord-256444-grw5s2pf	1107	26	.	.	.
cord-256444-grw5s2pf	1108	1	Cleavage	cleavage	NN
cord-256444-grw5s2pf	1108	2	of	of	IN
cord-256444-grw5s2pf	1108	3	the	the	DT
cord-256444-grw5s2pf	1108	4	MHV	MHV	NNP
cord-256444-grw5s2pf	1108	5	S	S	NNP
cord-256444-grw5s2pf	1108	6	protein	protein	NN
cord-256444-grw5s2pf	1108	7	occurred	occur	VBD
cord-256444-grw5s2pf	1108	8	after	after	IN
cord-256444-grw5s2pf	1108	9	conversion	conversion	NN
cord-256444-grw5s2pf	1108	10	of	of	IN
cord-256444-grw5s2pf	1108	11	the	the	DT
cord-256444-grw5s2pf	1108	12	glycans	glycan	NNS
cord-256444-grw5s2pf	1108	13	from	from	IN
cord-256444-grw5s2pf	1108	14	simple	simple	JJ
cord-256444-grw5s2pf	1108	15	to	to	IN
cord-256444-grw5s2pf	1108	16	complex	complex	JJ
cord-256444-grw5s2pf	1108	17	forms	form	NNS
cord-256444-grw5s2pf	1108	18	(	(	-LRB-
cord-256444-grw5s2pf	1108	19	Vennema	Vennema	NNP
cord-256444-grw5s2pf	1108	20	et	et	FW
cord-256444-grw5s2pf	1108	21	al	al	NNP
cord-256444-grw5s2pf	1108	22	.	.	NNP
cord-256444-grw5s2pf	1108	23	,	,	,
cord-256444-grw5s2pf	1108	24	1990a	1990a	CD
cord-256444-grw5s2pf	1108	25	)	)	-RRB-
cord-256444-grw5s2pf	1108	26	.	.	.
cord-256444-grw5s2pf	1109	1	After	after	IN
cord-256444-grw5s2pf	1109	2	cleavage	cleavage	NN
cord-256444-grw5s2pf	1109	3	,	,	,
cord-256444-grw5s2pf	1109	4	the	the	DT
cord-256444-grw5s2pf	1109	5	S1	S1	NNP
cord-256444-grw5s2pf	1109	6	and	and	CC
cord-256444-grw5s2pf	1109	7	S2	S2	NNP
cord-256444-grw5s2pf	1109	8	subunits	subunit	NNS
cord-256444-grw5s2pf	1109	9	are	be	VBP
cord-256444-grw5s2pf	1109	10	held	hold	VBN
cord-256444-grw5s2pf	1109	11	together	together	RB
cord-256444-grw5s2pf	1109	12	by	by	IN
cord-256444-grw5s2pf	1109	13	noncovalent	noncovalent	NN
cord-256444-grw5s2pf	1109	14	linkages	linkage	NNS
cord-256444-grw5s2pf	1109	15	(	(	-LRB-
cord-256444-grw5s2pf	1109	16	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	1109	17	et	et	NNP
cord-256444-grw5s2pf	1109	18	al	al	NNP
cord-256444-grw5s2pf	1109	19	.	.	NNP
cord-256444-grw5s2pf	1109	20	,	,	,
cord-256444-grw5s2pf	1109	21	1986b	1986b	CD
cord-256444-grw5s2pf	1109	22	;	;	:
cord-256444-grw5s2pf	1109	23	Sturman	Sturman	NNP
cord-256444-grw5s2pf	1109	24	et	et	NNP
cord-256444-grw5s2pf	1109	25	al	al	NNP
cord-256444-grw5s2pf	1109	26	.	.	NNP
cord-256444-grw5s2pf	1109	27	,	,	,
cord-256444-grw5s2pf	1109	28	1990	1990	CD
cord-256444-grw5s2pf	1109	29	)	)	-RRB-
cord-256444-grw5s2pf	1109	30	.	.	.
cord-256444-grw5s2pf	1110	1	The	the	DT
cord-256444-grw5s2pf	1110	2	S2	S2	NNP
cord-256444-grw5s2pf	1110	3	protein	protein	NN
cord-256444-grw5s2pf	1110	4	of	of	IN
cord-256444-grw5s2pf	1110	5	MHV	MHV	NNP
cord-256444-grw5s2pf	1110	6	is	be	VBZ
cord-256444-grw5s2pf	1110	7	acylated	acylate	VBN
cord-256444-grw5s2pf	1110	8	,	,	,
cord-256444-grw5s2pf	1110	9	possibly	possibly	RB
cord-256444-grw5s2pf	1110	10	involving	involve	VBG
cord-256444-grw5s2pf	1110	11	some	some	DT
cord-256444-grw5s2pf	1110	12	of	of	IN
cord-256444-grw5s2pf	1110	13	the	the	DT
cord-256444-grw5s2pf	1110	14	many	many	JJ
cord-256444-grw5s2pf	1110	15	cysteine	cysteine	NN
cord-256444-grw5s2pf	1110	16	residues	residue	NNS
cord-256444-grw5s2pf	1110	17	in	in	IN
cord-256444-grw5s2pf	1110	18	the	the	DT
cord-256444-grw5s2pf	1110	19	C	c	NN
cord-256444-grw5s2pf	1110	20	-	-	HYPH
cord-256444-grw5s2pf	1110	21	terminal	terminal	NN
cord-256444-grw5s2pf	1110	22	,	,	,
cord-256444-grw5s2pf	1110	23	hydrophilic	hydrophilic	JJ
cord-256444-grw5s2pf	1110	24	tail	tail	NN
cord-256444-grw5s2pf	1110	25	of	of	IN
cord-256444-grw5s2pf	1110	26	S	S	NNP
cord-256444-grw5s2pf	1110	27	(	(	-LRB-
cord-256444-grw5s2pf	1110	28	Schmidt	Schmidt	NNP
cord-256444-grw5s2pf	1110	29	,	,	,
cord-256444-grw5s2pf	1110	30	1982	1982	CD
cord-256444-grw5s2pf	1110	31	;	;	:
cord-256444-grw5s2pf	1111	1	Sturman	Sturman	NNP
cord-256444-grw5s2pf	1111	2	et	et	NNP
cord-256444-grw5s2pf	1111	3	al	al	NNP
cord-256444-grw5s2pf	1111	4	.	.	.
cord-256444-grw5s2pf	1112	1	,	,	,
cord-256444-grw5s2pf	1112	2	1985	1985	CD
cord-256444-grw5s2pf	1112	3	;	;	:
cord-256444-grw5s2pf	1112	4	van	van	NNP
cord-256444-grw5s2pf	1112	5	Berlo	Berlo	NNP
cord-256444-grw5s2pf	1112	6	et	et	NNP
cord-256444-grw5s2pf	1112	7	al	al	NNP
cord-256444-grw5s2pf	1112	8	.	.	NNP
cord-256444-grw5s2pf	1112	9	,	,	,
cord-256444-grw5s2pf	1112	10	1987	1987	CD
cord-256444-grw5s2pf	1112	11	)	)	-RRB-
cord-256444-grw5s2pf	1112	12	.	.	.
cord-256444-grw5s2pf	1113	1	The	the	DT
cord-256444-grw5s2pf	1113	2	processing	processing	NN
cord-256444-grw5s2pf	1113	3	of	of	IN
cord-256444-grw5s2pf	1113	4	S	S	NNP
cord-256444-grw5s2pf	1113	5	proteins	protein	NNS
cord-256444-grw5s2pf	1113	6	is	be	VBZ
cord-256444-grw5s2pf	1113	7	reviewed	review	VBN
cord-256444-grw5s2pf	1113	8	in	in	IN
cord-256444-grw5s2pf	1113	9	greater	great	JJR
cord-256444-grw5s2pf	1113	10	detail	detail	NN
cord-256444-grw5s2pf	1113	11	by	by	IN
cord-256444-grw5s2pf	1113	12	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	1113	13	.	.	.
cord-256444-grw5s2pf	1114	1	Modification	modification	NN
cord-256444-grw5s2pf	1114	2	of	of	IN
cord-256444-grw5s2pf	1114	3	the	the	DT
cord-256444-grw5s2pf	1114	4	M	M	NNP
cord-256444-grw5s2pf	1114	5	protein	protein	NN
cord-256444-grw5s2pf	1114	6	depends	depend	VBZ
cord-256444-grw5s2pf	1114	7	greatly	greatly	RB
cord-256444-grw5s2pf	1114	8	on	on	IN
cord-256444-grw5s2pf	1114	9	the	the	DT
cord-256444-grw5s2pf	1114	10	virus	virus	NN
cord-256444-grw5s2pf	1114	11	species	species	NN
cord-256444-grw5s2pf	1114	12	.	.	.
cord-256444-grw5s2pf	1115	1	The	the	DT
cord-256444-grw5s2pf	1115	2	major	major	JJ
cord-256444-grw5s2pf	1115	3	modification	modification	NN
cord-256444-grw5s2pf	1115	4	is	be	VBZ
cord-256444-grw5s2pf	1115	5	glycosylation	glycosylation	NN
cord-256444-grw5s2pf	1115	6	.	.	.
cord-256444-grw5s2pf	1116	1	The	the	DT
cord-256444-grw5s2pf	1116	2	oligosaccharides	oligosaccharide	NNS
cord-256444-grw5s2pf	1116	3	of	of	IN
cord-256444-grw5s2pf	1116	4	IBV	IBV	NNP
cord-256444-grw5s2pf	1116	5	and	and	CC
cord-256444-grw5s2pf	1116	6	the	the	DT
cord-256444-grw5s2pf	1116	7	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1116	8	group	group	NN
cord-256444-grw5s2pf	1116	9	are	be	VBP
cord-256444-grw5s2pf	1116	10	of	of	IN
cord-256444-grw5s2pf	1116	11	the	the	DT
cord-256444-grw5s2pf	1116	12	co	co	NN
cord-256444-grw5s2pf	1116	13	-	-	NN
cord-256444-grw5s2pf	1116	14	translationally	translationally	RB
cord-256444-grw5s2pf	1116	15	added	add	VBN
cord-256444-grw5s2pf	1116	16	N	n	NN
cord-256444-grw5s2pf	1116	17	-	-	HYPH
cord-256444-grw5s2pf	1116	18	linked	link	VBN
cord-256444-grw5s2pf	1116	19	glycans	glycan	NNS
cord-256444-grw5s2pf	1116	20	(	(	-LRB-
cord-256444-grw5s2pf	1116	21	Stern	Stern	NNP
cord-256444-grw5s2pf	1116	22	and	and	CC
cord-256444-grw5s2pf	1116	23	Sefton	Sefton	NNP
cord-256444-grw5s2pf	1116	24	,	,	,
cord-256444-grw5s2pf	1116	25	1982b	1982b	CD
cord-256444-grw5s2pf	1116	26	)	)	-RRB-
cord-256444-grw5s2pf	1116	27	.	.	.
cord-256444-grw5s2pf	1117	1	The	the	DT
cord-256444-grw5s2pf	1117	2	conversion	conversion	NN
cord-256444-grw5s2pf	1117	3	of	of	IN
cord-256444-grw5s2pf	1117	4	the	the	DT
cord-256444-grw5s2pf	1117	5	high	high	JJ
cord-256444-grw5s2pf	1117	6	mannose	mannose	NN
cord-256444-grw5s2pf	1117	7	to	to	IN
cord-256444-grw5s2pf	1117	8	complex	complex	JJ
cord-256444-grw5s2pf	1117	9	glycans	glycan	NNS
cord-256444-grw5s2pf	1117	10	is	be	VBZ
cord-256444-grw5s2pf	1117	11	not	not	RB
cord-256444-grw5s2pf	1117	12	very	very	RB
cord-256444-grw5s2pf	1117	13	efficient	efficient	JJ
cord-256444-grw5s2pf	1117	14	.	.	.
cord-256444-grw5s2pf	1118	1	In	in	IN
cord-256444-grw5s2pf	1118	2	contrast	contrast	NN
cord-256444-grw5s2pf	1118	3	,	,	,
cord-256444-grw5s2pf	1118	4	viruses	virus	NNS
cord-256444-grw5s2pf	1118	5	of	of	IN
cord-256444-grw5s2pf	1118	6	the	the	DT
cord-256444-grw5s2pf	1118	7	MHV	MHV	NNP
cord-256444-grw5s2pf	1118	8	group	group	NN
cord-256444-grw5s2pf	1118	9	have	have	VBP
cord-256444-grw5s2pf	1118	10	O	o	NN
cord-256444-grw5s2pf	1118	11	-	-	HYPH
cord-256444-grw5s2pf	1118	12	linked	link	VBN
cord-256444-grw5s2pf	1118	13	glycans	glycan	NNS
cord-256444-grw5s2pf	1118	14	which	which	WDT
cord-256444-grw5s2pf	1118	15	are	be	VBP
cord-256444-grw5s2pf	1118	16	added	add	VBN
cord-256444-grw5s2pf	1118	17	posttranslationally	posttranslationally	RB
cord-256444-grw5s2pf	1118	18	(	(	-LRB-
cord-256444-grw5s2pf	1118	19	Holmes	Holmes	NNP
cord-256444-grw5s2pf	1118	20	et	et	NNP
cord-256444-grw5s2pf	1118	21	al	al	NNP
cord-256444-grw5s2pf	1118	22	.	.	NNP
cord-256444-grw5s2pf	1118	23	,	,	,
cord-256444-grw5s2pf	1118	24	1981	1981	CD
cord-256444-grw5s2pf	1118	25	;	;	:
cord-256444-grw5s2pf	1118	26	Niemann	Niemann	NNP
cord-256444-grw5s2pf	1118	27	et	et	NNP
cord-256444-grw5s2pf	1118	28	al	al	NNP
cord-256444-grw5s2pf	1118	29	.	.	NNP
cord-256444-grw5s2pf	1118	30	,	,	,
cord-256444-grw5s2pf	1118	31	1982	1982	CD
cord-256444-grw5s2pf	1118	32	;	;	:
cord-256444-grw5s2pf	1118	33	1984	1984	CD
cord-256444-grw5s2pf	1118	34	;	;	.
cord-256444-grw5s2pf	1119	1	Tooze	Tooze	NNP
cord-256444-grw5s2pf	1119	2	et	et	NNP
cord-256444-grw5s2pf	1119	3	al	al	NNP
cord-256444-grw5s2pf	1119	4	.	.	.
cord-256444-grw5s2pf	1120	1	,	,	,
cord-256444-grw5s2pf	1120	2	1988	1988	CD
cord-256444-grw5s2pf	1120	3	;	;	:
cord-256444-grw5s2pf	1120	4	Locker	Locker	NNP
cord-256444-grw5s2pf	1120	5	et	et	NNP
cord-256444-grw5s2pf	1120	6	al	al	NNP
cord-256444-grw5s2pf	1120	7	.	.	NNP
cord-256444-grw5s2pf	1120	8	,	,	,
cord-256444-grw5s2pf	1120	9	1992a	1992a	CD
cord-256444-grw5s2pf	1120	10	;	;	:
cord-256444-grw5s2pf	1120	11	Krijnse	Krijnse	NNP
cord-256444-grw5s2pf	1120	12	-	-	HYPH
cord-256444-grw5s2pf	1120	13	Locker	Locker	NNP
cord-256444-grw5s2pf	1121	1	et	et	NNP
cord-256444-grw5s2pf	1121	2	al	al	NNP
cord-256444-grw5s2pf	1121	3	.	.	NNP
cord-256444-grw5s2pf	1121	4	,	,	,
cord-256444-grw5s2pf	1121	5	1994	1994	CD
cord-256444-grw5s2pf	1121	6	)	)	-RRB-
cord-256444-grw5s2pf	1121	7	.	.	.
cord-256444-grw5s2pf	1122	1	The	the	DT
cord-256444-grw5s2pf	1122	2	M	M	NNP
cord-256444-grw5s2pf	1122	3	protein	protein	NN
cord-256444-grw5s2pf	1122	4	of	of	IN
cord-256444-grw5s2pf	1122	5	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1122	6	is	be	VBZ
cord-256444-grw5s2pf	1122	7	also	also	RB
cord-256444-grw5s2pf	1122	8	sulfated	sulfate	VBN
cord-256444-grw5s2pf	1123	1	(	(	-LRB-
cord-256444-grw5s2pf	1123	2	Garwes	Garwes	NNP
cord-256444-grw5s2pf	1123	3	et	et	FW
cord-256444-grw5s2pf	1123	4	al	al	NNP
cord-256444-grw5s2pf	1123	5	.	.	NNP
cord-256444-grw5s2pf	1123	6	,	,	,
cord-256444-grw5s2pf	1123	7	19761	19761	CD
cord-256444-grw5s2pf	1123	8	,	,	,
cord-256444-grw5s2pf	1123	9	but	but	CC
cord-256444-grw5s2pf	1123	10	whether	whether	IN
cord-256444-grw5s2pf	1123	11	this	this	DT
cord-256444-grw5s2pf	1123	12	is	be	VBZ
cord-256444-grw5s2pf	1123	13	linked	link	VBN
cord-256444-grw5s2pf	1123	14	directly	directly	RB
cord-256444-grw5s2pf	1123	15	to	to	IN
cord-256444-grw5s2pf	1123	16	the	the	DT
cord-256444-grw5s2pf	1123	17	polypeptide	polypeptide	NN
cord-256444-grw5s2pf	1123	18	or	or	CC
cord-256444-grw5s2pf	1123	19	to	to	IN
cord-256444-grw5s2pf	1123	20	glycans	glycan	NNS
cord-256444-grw5s2pf	1123	21	is	be	VBZ
cord-256444-grw5s2pf	1123	22	unknown	unknown	JJ
cord-256444-grw5s2pf	1123	23	.	.	.
cord-256444-grw5s2pf	1124	1	Unlike	unlike	IN
cord-256444-grw5s2pf	1124	2	the	the	DT
cord-256444-grw5s2pf	1124	3	M	M	NNP
cord-256444-grw5s2pf	1124	4	proteins	protein	NNS
cord-256444-grw5s2pf	1124	5	of	of	IN
cord-256444-grw5s2pf	1124	6	IBV	IBV	NNP
cord-256444-grw5s2pf	1124	7	and	and	CC
cord-256444-grw5s2pf	1124	8	the	the	DT
cord-256444-grw5s2pf	1124	9	MHV	MHV	NNP
cord-256444-grw5s2pf	1124	10	group	group	NN
cord-256444-grw5s2pf	1124	11	,	,	,
cord-256444-grw5s2pf	1124	12	which	which	WDT
cord-256444-grw5s2pf	1124	13	have	have	VBP
cord-256444-grw5s2pf	1124	14	an	an	DT
cord-256444-grw5s2pf	1124	15	internal	internal	JJ
cord-256444-grw5s2pf	1124	16	membrane	membrane	NN
cord-256444-grw5s2pf	1124	17	insertion	insertion	NN
cord-256444-grw5s2pf	1124	18	sequence	sequence	NN
cord-256444-grw5s2pf	1124	19	,	,	,
cord-256444-grw5s2pf	1124	20	those	those	DT
cord-256444-grw5s2pf	1124	21	of	of	IN
cord-256444-grw5s2pf	1124	22	the	the	DT
cord-256444-grw5s2pf	1124	23	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1124	24	group	group	NN
cord-256444-grw5s2pf	1124	25	have	have	VBP
cord-256444-grw5s2pf	1124	26	an	an	DT
cord-256444-grw5s2pf	1124	27	N	n	CD
cord-256444-grw5s2pf	1124	28	-	-	HYPH
cord-256444-grw5s2pf	1124	29	terminal	terminal	NN
cord-256444-grw5s2pf	1124	30	membrane	membrane	NN
cord-256444-grw5s2pf	1124	31	insertion	insertion	NN
cord-256444-grw5s2pf	1124	32	sequence	sequence	NN
cord-256444-grw5s2pf	1124	33	that	that	WDT
cord-256444-grw5s2pf	1124	34	is	be	VBZ
cord-256444-grw5s2pf	1124	35	absent	absent	JJ
cord-256444-grw5s2pf	1124	36	from	from	IN
cord-256444-grw5s2pf	1124	37	the	the	DT
cord-256444-grw5s2pf	1124	38	mature	mature	JJ
cord-256444-grw5s2pf	1124	39	M	M	NNP
cord-256444-grw5s2pf	1124	40	protein	protein	NN
cord-256444-grw5s2pf	1124	41	(	(	-LRB-
cord-256444-grw5s2pf	1124	42	Laude	Laude	NNP
cord-256444-grw5s2pf	1124	43	et	et	FW
cord-256444-grw5s2pf	1124	44	al	al	NNP
cord-256444-grw5s2pf	1124	45	.	.	NNP
cord-256444-grw5s2pf	1124	46	,	,	,
cord-256444-grw5s2pf	1124	47	1987	1987	CD
cord-256444-grw5s2pf	1124	48	)	)	-RRB-
cord-256444-grw5s2pf	1124	49	.	.	.
cord-256444-grw5s2pf	1125	1	This	this	DT
cord-256444-grw5s2pf	1125	2	signal	signal	NN
cord-256444-grw5s2pf	1125	3	sequence	sequence	NN
cord-256444-grw5s2pf	1125	4	,	,	,
cord-256444-grw5s2pf	1125	5	however	however	RB
cord-256444-grw5s2pf	1125	6	,	,	,
cord-256444-grw5s2pf	1125	7	is	be	VBZ
cord-256444-grw5s2pf	1125	8	not	not	RB
cord-256444-grw5s2pf	1125	9	an	an	DT
cord-256444-grw5s2pf	1125	10	essential	essential	JJ
cord-256444-grw5s2pf	1125	11	requirement	requirement	NN
cord-256444-grw5s2pf	1125	12	for	for	IN
cord-256444-grw5s2pf	1125	13	the	the	DT
cord-256444-grw5s2pf	1125	14	membrane	membrane	NN
cord-256444-grw5s2pf	1125	15	insertion	insertion	NN
cord-256444-grw5s2pf	1125	16	of	of	IN
cord-256444-grw5s2pf	1125	17	the	the	DT
cord-256444-grw5s2pf	1125	18	M	M	NNP
cord-256444-grw5s2pf	1125	19	protein	protein	NN
cord-256444-grw5s2pf	1125	20	(	(	-LRB-
cord-256444-grw5s2pf	1125	21	Kapke	Kapke	NNP
cord-256444-grw5s2pf	1125	22	et	et	NNP
cord-256444-grw5s2pf	1125	23	al	al	NNP
cord-256444-grw5s2pf	1125	24	.	.	NNP
cord-256444-grw5s2pf	1125	25	,	,	,
cord-256444-grw5s2pf	1125	26	1988	1988	CD
cord-256444-grw5s2pf	1125	27	;	;	:
cord-256444-grw5s2pf	1125	28	Vennema	Vennema	NNP
cord-256444-grw5s2pf	1125	29	et	et	FW
cord-256444-grw5s2pf	1125	30	al	al	NNP
cord-256444-grw5s2pf	1125	31	.	.	NNP
cord-256444-grw5s2pf	1125	32	,	,	,
cord-256444-grw5s2pf	1125	33	1991	1991	CD
cord-256444-grw5s2pf	1125	34	)	)	-RRB-
cord-256444-grw5s2pf	1125	35	.	.	.
cord-256444-grw5s2pf	1126	1	3	3	LS
cord-256444-grw5s2pf	1126	2	.	.	.
cord-256444-grw5s2pf	1127	1	HE	HE	NNP
cord-256444-grw5s2pf	1127	2	protein	protein	NN
cord-256444-grw5s2pf	1127	3	.	.	.
cord-256444-grw5s2pf	1128	1	The	the	DT
cord-256444-grw5s2pf	1128	2	HE	HE	NNP
cord-256444-grw5s2pf	1128	3	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1128	4	has	have	VBZ
cord-256444-grw5s2pf	1128	5	N	n	CD
cord-256444-grw5s2pf	1128	6	-	-	HYPH
cord-256444-grw5s2pf	1128	7	linked	link	VBN
cord-256444-grw5s2pf	1128	8	glycans	glycan	NNS
cord-256444-grw5s2pf	1128	9	which	which	WDT
cord-256444-grw5s2pf	1128	10	are	be	VBP
cord-256444-grw5s2pf	1128	11	converted	convert	VBN
cord-256444-grw5s2pf	1128	12	to	to	IN
cord-256444-grw5s2pf	1128	13	complex	complex	JJ
cord-256444-grw5s2pf	1128	14	ones	one	NNS
cord-256444-grw5s2pf	1128	15	in	in	IN
cord-256444-grw5s2pf	1128	16	the	the	DT
cord-256444-grw5s2pf	1128	17	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1128	18	complex	complex	NN
cord-256444-grw5s2pf	1128	19	.	.	.
cord-256444-grw5s2pf	1129	1	The	the	DT
cord-256444-grw5s2pf	1129	2	N	n	CD
cord-256444-grw5s2pf	1129	3	-	-	HYPH
cord-256444-grw5s2pf	1129	4	terminal	terminal	JJ
cord-256444-grw5s2pf	1129	5	signal	signal	NN
cord-256444-grw5s2pf	1129	6	sequence	sequence	NN
cord-256444-grw5s2pf	1129	7	is	be	VBZ
cord-256444-grw5s2pf	1129	8	cleaved	cleave	VBN
cord-256444-grw5s2pf	1129	9	from	from	IN
cord-256444-grw5s2pf	1129	10	the	the	DT
cord-256444-grw5s2pf	1129	11	mature	mature	JJ
cord-256444-grw5s2pf	1129	12	protein	protein	NN
cord-256444-grw5s2pf	1129	13	,	,	,
cord-256444-grw5s2pf	1129	14	which	which	WDT
cord-256444-grw5s2pf	1129	15	then	then	RB
cord-256444-grw5s2pf	1129	16	forms	form	VBZ
cord-256444-grw5s2pf	1129	17	dimers	dimer	NNS
cord-256444-grw5s2pf	1129	18	by	by	IN
cord-256444-grw5s2pf	1129	19	disulfide	disulfide	JJ
cord-256444-grw5s2pf	1129	20	bonds	bond	NNS
cord-256444-grw5s2pf	1130	1	(	(	-LRB-
cord-256444-grw5s2pf	1130	2	King	King	NNP
cord-256444-grw5s2pf	1130	3	et	et	NNP
cord-256444-grw5s2pf	1130	4	al	al	NNP
cord-256444-grw5s2pf	1130	5	.	.	NNP
cord-256444-grw5s2pf	1130	6	,	,	,
cord-256444-grw5s2pf	1130	7	1985	1985	CD
cord-256444-grw5s2pf	1130	8	;	;	:
cord-256444-grw5s2pf	1130	9	Hogue	Hogue	NNP
cord-256444-grw5s2pf	1130	10	et	et	NNP
cord-256444-grw5s2pf	1130	11	al	al	NNP
cord-256444-grw5s2pf	1130	12	.	.	NNP
cord-256444-grw5s2pf	1130	13	,	,	,
cord-256444-grw5s2pf	1130	14	1989	1989	CD
cord-256444-grw5s2pf	1130	15	;	;	:
cord-256444-grw5s2pf	1131	1	Kienzle	Kienzle	NNP
cord-256444-grw5s2pf	1131	2	et	et	IN
cord-256444-grw5s2pf	1131	3	al	al	NNP
cord-256444-grw5s2pf	1131	4	.	.	.
cord-256444-grw5s2pf	1132	1	,	,	,
cord-256444-grw5s2pf	1132	2	1990	1990	CD
cord-256444-grw5s2pf	1132	3	;	;	:
cord-256444-grw5s2pf	1132	4	Yo0	Yo0	NNP
cord-256444-grw5s2pf	1132	5	et	et	NNP
cord-256444-grw5s2pf	1132	6	al	al	NNP
cord-256444-grw5s2pf	1132	7	.	.	NNP
cord-256444-grw5s2pf	1132	8	,	,	,
cord-256444-grw5s2pf	1132	9	1992	1992	CD
cord-256444-grw5s2pf	1132	10	)	)	-RRB-
cord-256444-grw5s2pf	1132	11	.	.	.
cord-256444-grw5s2pf	1133	1	of	of	IN
cord-256444-grw5s2pf	1133	2	MHV	MHV	NNP
cord-256444-grw5s2pf	1133	3	E	e	NN
cord-256444-grw5s2pf	1133	4	protein	protein	NN
cord-256444-grw5s2pf	1133	5	(	(	-LRB-
cord-256444-grw5s2pf	1133	6	Yu	Yu	NNP
cord-256444-grw5s2pf	1133	7	et	et	FW
cord-256444-grw5s2pf	1133	8	al	al	NNP
cord-256444-grw5s2pf	1133	9	.	.	NNP
cord-256444-grw5s2pf	1133	10	,	,	,
cord-256444-grw5s2pf	1133	11	1994	1994	CD
cord-256444-grw5s2pf	1133	12	)	)	-RRB-
cord-256444-grw5s2pf	1133	13	.	.	.
cord-256444-grw5s2pf	1134	1	However	however	RB
cord-256444-grw5s2pf	1134	2	,	,	,
cord-256444-grw5s2pf	1134	3	this	this	DT
cord-256444-grw5s2pf	1134	4	was	be	VBD
cord-256444-grw5s2pf	1134	5	not	not	RB
cord-256444-grw5s2pf	1134	6	observed	observe	VBN
cord-256444-grw5s2pf	1134	7	for	for	IN
cord-256444-grw5s2pf	1134	8	the	the	DT
cord-256444-grw5s2pf	1134	9	E	e	NN
cord-256444-grw5s2pf	1134	10	protein	protein	NN
cord-256444-grw5s2pf	1134	11	of	of	IN
cord-256444-grw5s2pf	1134	12	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1134	13	when	when	WRB
cord-256444-grw5s2pf	1134	14	expressed	express	VBN
cord-256444-grw5s2pf	1134	15	in	in	IN
cord-256444-grw5s2pf	1134	16	insect	insect	NN
cord-256444-grw5s2pf	1134	17	cells	cell	NNS
cord-256444-grw5s2pf	1134	18	(	(	-LRB-
cord-256444-grw5s2pf	1134	19	Godet	Godet	NNP
cord-256444-grw5s2pf	1134	20	et	et	NNP
cord-256444-grw5s2pf	1134	21	al	al	NNP
cord-256444-grw5s2pf	1134	22	.	.	NNP
cord-256444-grw5s2pf	1134	23	,	,	,
cord-256444-grw5s2pf	1134	24	1992	1992	CD
cord-256444-grw5s2pf	1134	25	)	)	-RRB-
cord-256444-grw5s2pf	1134	26	.	.	.
cord-256444-grw5s2pf	1135	1	5	5	LS
cord-256444-grw5s2pf	1135	2	.	.	.
cord-256444-grw5s2pf	1136	1	Nprotein	Nprotein	NNP
cord-256444-grw5s2pf	1136	2	.	.	.
cord-256444-grw5s2pf	1137	1	The	the	DT
cord-256444-grw5s2pf	1137	2	N	N	NNP
cord-256444-grw5s2pf	1137	3	protein	protein	NN
cord-256444-grw5s2pf	1137	4	is	be	VBZ
cord-256444-grw5s2pf	1137	5	phosphorylated	phosphorylate	VBN
cord-256444-grw5s2pf	1137	6	,	,	,
cord-256444-grw5s2pf	1137	7	the	the	DT
cord-256444-grw5s2pf	1137	8	phosphate	phosphate	NN
cord-256444-grw5s2pf	1137	9	linkage	linkage	NN
cord-256444-grw5s2pf	1137	10	being	be	VBG
cord-256444-grw5s2pf	1137	11	exclusively	exclusively	RB
cord-256444-grw5s2pf	1137	12	to	to	IN
cord-256444-grw5s2pf	1137	13	serine	serine	NN
cord-256444-grw5s2pf	1137	14	residues	residue	NNS
cord-256444-grw5s2pf	1137	15	(	(	-LRB-
cord-256444-grw5s2pf	1137	16	Stohlman	Stohlman	NNP
cord-256444-grw5s2pf	1137	17	and	and	CC
cord-256444-grw5s2pf	1137	18	Lai	Lai	NNP
cord-256444-grw5s2pf	1137	19	,	,	,
cord-256444-grw5s2pf	1137	20	1979	1979	CD
cord-256444-grw5s2pf	1137	21	)	)	-RRB-
cord-256444-grw5s2pf	1137	22	.	.	.
cord-256444-grw5s2pf	1138	1	The	the	DT
cord-256444-grw5s2pf	1138	2	role	role	NN
cord-256444-grw5s2pf	1138	3	of	of	IN
cord-256444-grw5s2pf	1138	4	phosphorylation	phosphorylation	NN
cord-256444-grw5s2pf	1138	5	is	be	VBZ
cord-256444-grw5s2pf	1138	6	unknown	unknown	JJ
cord-256444-grw5s2pf	1138	7	.	.	.
cord-256444-grw5s2pf	1139	1	In	in	IN
cord-256444-grw5s2pf	1139	2	virus	virus	NN
cord-256444-grw5s2pf	1139	3	-	-	HYPH
cord-256444-grw5s2pf	1139	4	infected	infect	VBN
cord-256444-grw5s2pf	1139	5	cells	cell	NNS
cord-256444-grw5s2pf	1139	6	,	,	,
cord-256444-grw5s2pf	1139	7	the	the	DT
cord-256444-grw5s2pf	1139	8	assembly	assembly	NN
cord-256444-grw5s2pf	1139	9	of	of	IN
cord-256444-grw5s2pf	1139	10	virus	virus	NN
cord-256444-grw5s2pf	1139	11	particles	particle	NNS
cord-256444-grw5s2pf	1139	12	presumably	presumably	RB
cord-256444-grw5s2pf	1139	13	starts	start	VBZ
cord-256444-grw5s2pf	1139	14	with	with	IN
cord-256444-grw5s2pf	1139	15	the	the	DT
cord-256444-grw5s2pf	1139	16	formation	formation	NN
cord-256444-grw5s2pf	1139	17	of	of	IN
cord-256444-grw5s2pf	1139	18	RNP	RNP	NNP
cord-256444-grw5s2pf	1139	19	,	,	,
cord-256444-grw5s2pf	1139	20	which	which	WDT
cord-256444-grw5s2pf	1139	21	interacts	interact	VBZ
cord-256444-grw5s2pf	1139	22	with	with	IN
cord-256444-grw5s2pf	1139	23	the	the	DT
cord-256444-grw5s2pf	1139	24	components	component	NNS
cord-256444-grw5s2pf	1139	25	of	of	IN
cord-256444-grw5s2pf	1139	26	viral	viral	JJ
cord-256444-grw5s2pf	1139	27	envelope	envelope	NN
cord-256444-grw5s2pf	1139	28	proteins	protein	NNS
cord-256444-grw5s2pf	1139	29	to	to	TO
cord-256444-grw5s2pf	1139	30	form	form	VB
cord-256444-grw5s2pf	1139	31	enveloped	envelop	VBN
cord-256444-grw5s2pf	1139	32	virus	virus	NN
cord-256444-grw5s2pf	1139	33	particles	particle	NNS
cord-256444-grw5s2pf	1139	34	and	and	CC
cord-256444-grw5s2pf	1139	35	bud	bud	NN
cord-256444-grw5s2pf	1139	36	into	into	IN
cord-256444-grw5s2pf	1139	37	the	the	DT
cord-256444-grw5s2pf	1139	38	endoplasmic	endoplasmic	NN
cord-256444-grw5s2pf	1139	39	reticulum	reticulum	NN
cord-256444-grw5s2pf	1139	40	(	(	-LRB-
cord-256444-grw5s2pf	1139	41	ER	ER	NNP
cord-256444-grw5s2pf	1139	42	)	)	-RRB-
cord-256444-grw5s2pf	1139	43	and	and	CC
cord-256444-grw5s2pf	1139	44	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1139	45	complex	complex	NN
cord-256444-grw5s2pf	1139	46	.	.	.
cord-256444-grw5s2pf	1140	1	Several	several	JJ
cord-256444-grw5s2pf	1140	2	recent	recent	JJ
cord-256444-grw5s2pf	1140	3	advances	advance	NNS
cord-256444-grw5s2pf	1140	4	shed	shed	VBP
cord-256444-grw5s2pf	1140	5	light	light	NN
cord-256444-grw5s2pf	1140	6	on	on	IN
cord-256444-grw5s2pf	1140	7	this	this	DT
cord-256444-grw5s2pf	1140	8	process	process	NN
cord-256444-grw5s2pf	1140	9	:	:	:
cord-256444-grw5s2pf	1140	10	Early	early	JJ
cord-256444-grw5s2pf	1140	11	studies	study	NNS
cord-256444-grw5s2pf	1140	12	have	have	VBP
cord-256444-grw5s2pf	1140	13	shown	show	VBN
cord-256444-grw5s2pf	1140	14	that	that	IN
cord-256444-grw5s2pf	1140	15	the	the	DT
cord-256444-grw5s2pf	1140	16	S	S	NNP
cord-256444-grw5s2pf	1140	17	proteins	protein	NNS
cord-256444-grw5s2pf	1140	18	are	be	VBP
cord-256444-grw5s2pf	1140	19	not	not	RB
cord-256444-grw5s2pf	1140	20	necessary	necessary	JJ
cord-256444-grw5s2pf	1140	21	for	for	IN
cord-256444-grw5s2pf	1140	22	virus	virus	NN
cord-256444-grw5s2pf	1140	23	particle	particle	NN
cord-256444-grw5s2pf	1140	24	formation	formation	NN
cord-256444-grw5s2pf	1140	25	;	;	:
cord-256444-grw5s2pf	1140	26	thus	thus	RB
cord-256444-grw5s2pf	1140	27	,	,	,
cord-256444-grw5s2pf	1140	28	denuded	denude	VBN
cord-256444-grw5s2pf	1140	29	virus	virus	NN
cord-256444-grw5s2pf	1140	30	particles	particle	NNS
cord-256444-grw5s2pf	1140	31	without	without	IN
cord-256444-grw5s2pf	1140	32	spikes	spike	NNS
cord-256444-grw5s2pf	1140	33	can	can	MD
cord-256444-grw5s2pf	1140	34	be	be	VB
cord-256444-grw5s2pf	1140	35	formed	form	VBN
cord-256444-grw5s2pf	1140	36	in	in	IN
cord-256444-grw5s2pf	1140	37	the	the	DT
cord-256444-grw5s2pf	1140	38	virus	virus	NN
cord-256444-grw5s2pf	1140	39	-	-	HYPH
cord-256444-grw5s2pf	1140	40	infected	infect	VBN
cord-256444-grw5s2pf	1140	41	cells	cell	NNS
cord-256444-grw5s2pf	1140	42	treated	treat	VBN
cord-256444-grw5s2pf	1140	43	with	with	IN
cord-256444-grw5s2pf	1140	44	tunicamycin	tunicamycin	NNS
cord-256444-grw5s2pf	1140	45	,	,	,
cord-256444-grw5s2pf	1140	46	which	which	WDT
cord-256444-grw5s2pf	1140	47	inhibits	inhibit	VBZ
cord-256444-grw5s2pf	1140	48	N	n	CD
cord-256444-grw5s2pf	1140	49	-	-	HYPH
cord-256444-grw5s2pf	1140	50	glycosylation	glycosylation	NN
cord-256444-grw5s2pf	1140	51	and	and	CC
cord-256444-grw5s2pf	1140	52	transport	transport	NN
cord-256444-grw5s2pf	1140	53	of	of	IN
cord-256444-grw5s2pf	1140	54	the	the	DT
cord-256444-grw5s2pf	1140	55	S	S	NNP
cord-256444-grw5s2pf	1140	56	and	and	CC
cord-256444-grw5s2pf	1140	57	HE	HE	NNP
cord-256444-grw5s2pf	1140	58	proteins	protein	VBZ
cord-256444-grw5s2pf	1141	1	(	(	-LRB-
cord-256444-grw5s2pf	1141	2	Holmes	Holmes	NNP
cord-256444-grw5s2pf	1141	3	et	et	NNP
cord-256444-grw5s2pf	1141	4	al	al	NNP
cord-256444-grw5s2pf	1141	5	.	.	NNP
cord-256444-grw5s2pf	1141	6	,	,	,
cord-256444-grw5s2pf	1141	7	1981	1981	CD
cord-256444-grw5s2pf	1141	8	)	)	-RRB-
cord-256444-grw5s2pf	1141	9	.	.	.
cord-256444-grw5s2pf	1142	1	Further	further	RB
cord-256444-grw5s2pf	1142	2	,	,	,
cord-256444-grw5s2pf	1142	3	recent	recent	JJ
cord-256444-grw5s2pf	1142	4	studies	study	NNS
cord-256444-grw5s2pf	1142	5	have	have	VBP
cord-256444-grw5s2pf	1142	6	shown	show	VBN
cord-256444-grw5s2pf	1142	7	that	that	IN
cord-256444-grw5s2pf	1142	8	the	the	DT
cord-256444-grw5s2pf	1142	9	minimum	minimum	JJ
cord-256444-grw5s2pf	1142	10	requirement	requirement	NN
cord-256444-grw5s2pf	1142	11	for	for	IN
cord-256444-grw5s2pf	1142	12	the	the	DT
cord-256444-grw5s2pf	1142	13	formation	formation	NN
cord-256444-grw5s2pf	1142	14	of	of	IN
cord-256444-grw5s2pf	1142	15	viruslike	viruslike	JJ
cord-256444-grw5s2pf	1142	16	particles	particle	NNS
cord-256444-grw5s2pf	1142	17	(	(	-LRB-
cord-256444-grw5s2pf	1142	18	VLP	VLP	NNP
cord-256444-grw5s2pf	1142	19	)	)	-RRB-
cord-256444-grw5s2pf	1142	20	,	,	,
cord-256444-grw5s2pf	1142	21	i.e.	i.e.	FW
cord-256444-grw5s2pf	1142	22	,	,	,
cord-256444-grw5s2pf	1142	23	empty	empty	JJ
cord-256444-grw5s2pf	1142	24	virus	virus	NN
cord-256444-grw5s2pf	1142	25	particles	particle	NNS
cord-256444-grw5s2pf	1142	26	,	,	,
cord-256444-grw5s2pf	1142	27	is	be	VBZ
cord-256444-grw5s2pf	1142	28	the	the	DT
cord-256444-grw5s2pf	1142	29	M	M	NNP
cord-256444-grw5s2pf	1142	30	and	and	CC
cord-256444-grw5s2pf	1142	31	E	e	NN
cord-256444-grw5s2pf	1142	32	proteins	protein	NNS
cord-256444-grw5s2pf	1142	33	(	(	-LRB-
cord-256444-grw5s2pf	1142	34	Bos	Bos	NNP
cord-256444-grw5s2pf	1142	35	et	et	NNP
cord-256444-grw5s2pf	1142	36	al	al	NNP
cord-256444-grw5s2pf	1142	37	.	.	.
cord-256444-grw5s2pf	1143	1	,	,	,
cord-256444-grw5s2pf	1143	2	1996	1996	CD
cord-256444-grw5s2pf	1143	3	;	;	:
cord-256444-grw5s2pf	1143	4	Vennema	Vennema	NNP
cord-256444-grw5s2pf	1143	5	et	et	FW
cord-256444-grw5s2pf	1143	6	al	al	NNP
cord-256444-grw5s2pf	1143	7	.	.	NNP
cord-256444-grw5s2pf	1143	8	,	,	,
cord-256444-grw5s2pf	1143	9	1996	1996	CD
cord-256444-grw5s2pf	1143	10	)	)	-RRB-
cord-256444-grw5s2pf	1143	11	;	;	:
cord-256444-grw5s2pf	1143	12	2	2	CD
cord-256444-grw5s2pf	1143	13	.	.	.
cord-256444-grw5s2pf	1144	1	The	the	DT
cord-256444-grw5s2pf	1144	2	sites	site	NNS
cord-256444-grw5s2pf	1144	3	of	of	IN
cord-256444-grw5s2pf	1144	4	virus	virus	NN
cord-256444-grw5s2pf	1144	5	budding	bud	VBG
cord-256444-grw5s2pf	1144	6	are	be	VBP
cord-256444-grw5s2pf	1144	7	in	in	IN
cord-256444-grw5s2pf	1144	8	the	the	DT
cord-256444-grw5s2pf	1144	9	ER	ER	NNP
cord-256444-grw5s2pf	1144	10	and	and	CC
cord-256444-grw5s2pf	1144	11	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1144	12	,	,	,
cord-256444-grw5s2pf	1144	13	near	near	IN
cord-256444-grw5s2pf	1144	14	the	the	DT
cord-256444-grw5s2pf	1144	15	sites	site	NNS
cord-256444-grw5s2pf	1144	16	of	of	IN
cord-256444-grw5s2pf	1144	17	accumulation	accumulation	NN
cord-256444-grw5s2pf	1144	18	of	of	IN
cord-256444-grw5s2pf	1144	19	the	the	DT
cord-256444-grw5s2pf	1144	20	M	M	NNP
cord-256444-grw5s2pf	1144	21	protein	protein	NN
cord-256444-grw5s2pf	1144	22	(	(	-LRB-
cord-256444-grw5s2pf	1144	23	Dubois	Dubois	NNP
cord-256444-grw5s2pf	1144	24	-	-	HYPH
cord-256444-grw5s2pf	1144	25	Dalcq	Dalcq	NNP
cord-256444-grw5s2pf	1144	26	et	et	NNP
cord-256444-grw5s2pf	1144	27	al	al	NNP
cord-256444-grw5s2pf	1144	28	.	.	NNP
cord-256444-grw5s2pf	1144	29	,	,	,
cord-256444-grw5s2pf	1144	30	1982	1982	CD
cord-256444-grw5s2pf	1144	31	;	;	:
cord-256444-grw5s2pf	1144	32	Tooze	Tooze	NNP
cord-256444-grw5s2pf	1144	33	et	et	NNP
cord-256444-grw5s2pf	1144	34	al	al	NNP
cord-256444-grw5s2pf	1144	35	.	.	NNP
cord-256444-grw5s2pf	1144	36	,	,	,
cord-256444-grw5s2pf	1144	37	1984	1984	CD
cord-256444-grw5s2pf	1144	38	;	;	.
cord-256444-grw5s2pf	1145	1	Tooze	Tooze	NNP
cord-256444-grw5s2pf	1145	2	and	and	CC
cord-256444-grw5s2pf	1145	3	Tooze	Tooze	NNP
cord-256444-grw5s2pf	1145	4	,	,	,
cord-256444-grw5s2pf	1145	5	1985	1985	CD
cord-256444-grw5s2pf	1145	6	;	;	:
cord-256444-grw5s2pf	1145	7	Klumperman	Klumperman	NNP
cord-256444-grw5s2pf	1145	8	et	et	FW
cord-256444-grw5s2pf	1145	9	al	al	NNP
cord-256444-grw5s2pf	1145	10	.	.	NNP
cord-256444-grw5s2pf	1145	11	,	,	,
cord-256444-grw5s2pf	1145	12	1994	1994	CD
cord-256444-grw5s2pf	1145	13	)	)	-RRB-
cord-256444-grw5s2pf	1145	14	;	;	:
cord-256444-grw5s2pf	1145	15	thus	thus	RB
cord-256444-grw5s2pf	1145	16	,	,	,
cord-256444-grw5s2pf	1145	17	the	the	DT
cord-256444-grw5s2pf	1145	18	interaction	interaction	NN
cord-256444-grw5s2pf	1145	19	between	between	IN
cord-256444-grw5s2pf	1145	20	the	the	DT
cord-256444-grw5s2pf	1145	21	M	M	NNP
cord-256444-grw5s2pf	1145	22	and	and	CC
cord-256444-grw5s2pf	1145	23	E	e	NN
cord-256444-grw5s2pf	1145	24	proteins	protein	NNS
cord-256444-grw5s2pf	1145	25	appears	appear	VBZ
cord-256444-grw5s2pf	1145	26	to	to	TO
cord-256444-grw5s2pf	1145	27	be	be	VB
cord-256444-grw5s2pf	1145	28	the	the	DT
cord-256444-grw5s2pf	1145	29	key	key	JJ
cord-256444-grw5s2pf	1145	30	event	event	NN
cord-256444-grw5s2pf	1145	31	for	for	IN
cord-256444-grw5s2pf	1145	32	virus	virus	NN
cord-256444-grw5s2pf	1145	33	particle	particle	NN
cord-256444-grw5s2pf	1145	34	assembly	assembly	NN
cord-256444-grw5s2pf	1145	35	.	.	.
cord-256444-grw5s2pf	1146	1	The	the	DT
cord-256444-grw5s2pf	1146	2	incorporation	incorporation	NN
cord-256444-grw5s2pf	1146	3	of	of	IN
cord-256444-grw5s2pf	1146	4	the	the	DT
cord-256444-grw5s2pf	1146	5	nucleocapsids	nucleocapsid	NNS
cord-256444-grw5s2pf	1146	6	and	and	CC
cord-256444-grw5s2pf	1146	7	S	S	NNP
cord-256444-grw5s2pf	1146	8	and	and	CC
cord-256444-grw5s2pf	1146	9	HE	HE	NNP
cord-256444-grw5s2pf	1146	10	proteins	protein	VBZ
cord-256444-grw5s2pf	1146	11	into	into	IN
cord-256444-grw5s2pf	1146	12	virus	virus	NN
cord-256444-grw5s2pf	1146	13	particles	particle	NNS
cord-256444-grw5s2pf	1146	14	may	may	MD
cord-256444-grw5s2pf	1146	15	involve	involve	VB
cord-256444-grw5s2pf	1146	16	subsequent	subsequent	JJ
cord-256444-grw5s2pf	1146	17	interactions	interaction	NNS
cord-256444-grw5s2pf	1146	18	of	of	IN
cord-256444-grw5s2pf	1146	19	these	these	DT
cord-256444-grw5s2pf	1146	20	components	component	NNS
cord-256444-grw5s2pf	1146	21	with	with	IN
cord-256444-grw5s2pf	1146	22	the	the	DT
cord-256444-grw5s2pf	1146	23	M	M	NNP
cord-256444-grw5s2pf	1146	24	-	-	HYPH
cord-256444-grw5s2pf	1146	25	E	E	NNP
cord-256444-grw5s2pf	1146	26	complex	complex	NN
cord-256444-grw5s2pf	1146	27	.	.	.
cord-256444-grw5s2pf	1147	1	The	the	DT
cord-256444-grw5s2pf	1147	2	virus	virus	NN
cord-256444-grw5s2pf	1147	3	assembly	assembly	NN
cord-256444-grw5s2pf	1147	4	and	and	CC
cord-256444-grw5s2pf	1147	5	release	release	NN
cord-256444-grw5s2pf	1147	6	process	process	NN
cord-256444-grw5s2pf	1147	7	has	have	VBZ
cord-256444-grw5s2pf	1147	8	been	be	VBN
cord-256444-grw5s2pf	1147	9	studied	study	VBN
cord-256444-grw5s2pf	1147	10	in	in	IN
cord-256444-grw5s2pf	1147	11	most	most	JJS
cord-256444-grw5s2pf	1147	12	detail	detail	NN
cord-256444-grw5s2pf	1147	13	for	for	IN
cord-256444-grw5s2pf	1147	14	MHV	MHV	NNP
cord-256444-grw5s2pf	1147	15	(	(	-LRB-
cord-256444-grw5s2pf	1147	16	J.	J.	NNP
cord-256444-grw5s2pf	1147	17	Tooze	Tooze	NNP
cord-256444-grw5s2pf	1147	18	et	et	NNP
cord-256444-grw5s2pf	1147	19	al	al	NNP
cord-256444-grw5s2pf	1147	20	.	.	.
cord-256444-grw5s2pf	1148	1	,	,	,
cord-256444-grw5s2pf	1148	2	1984	1984	CD
cord-256444-grw5s2pf	1149	1	Tooze	Tooze	NNP
cord-256444-grw5s2pf	1149	2	et	et	NNP
cord-256444-grw5s2pf	1149	3	al	al	NNP
cord-256444-grw5s2pf	1149	4	.	.	.
cord-256444-grw5s2pf	1150	1	,	,	,
cord-256444-grw5s2pf	1150	2	,	,	,
cord-256444-grw5s2pf	1150	3	1987	1987	CD
cord-256444-grw5s2pf	1150	4	Tooze	Tooze	NNP
cord-256444-grw5s2pf	1150	5	and	and	CC
cord-256444-grw5s2pf	1150	6	Tooze	Tooze	NNP
cord-256444-grw5s2pf	1150	7	,	,	,
cord-256444-grw5s2pf	1150	8	1985	1985	CD
cord-256444-grw5s2pf	1150	9	;	;	:
cord-256444-grw5s2pf	1150	10	S.	S.	NNP
cord-256444-grw5s2pf	1150	11	A.	a.	NN
cord-256444-grw5s2pf	1150	12	Tooze	Tooze	NNP
cord-256444-grw5s2pf	1150	13	et	et	NNP
cord-256444-grw5s2pf	1150	14	al	al	NNP
cord-256444-grw5s2pf	1150	15	.	.	NNP
cord-256444-grw5s2pf	1150	16	,	,	,
cord-256444-grw5s2pf	1150	17	1988	1988	CD
cord-256444-grw5s2pf	1150	18	;	;	:
cord-256444-grw5s2pf	1150	19	Krijnse	Krijnse	NNP
cord-256444-grw5s2pf	1150	20	-	-	HYPH
cord-256444-grw5s2pf	1150	21	Locker	Locker	NNP
cord-256444-grw5s2pf	1150	22	et	et	FW
cord-256444-grw5s2pf	1150	23	al	al	NNP
cord-256444-grw5s2pf	1150	24	.	.	NNP
cord-256444-grw5s2pf	1150	25	,	,	,
cord-256444-grw5s2pf	1150	26	1994	1994	CD
cord-256444-grw5s2pf	1150	27	)	)	-RRB-
cord-256444-grw5s2pf	1150	28	,	,	,
cord-256444-grw5s2pf	1150	29	and	and	CC
cord-256444-grw5s2pf	1150	30	the	the	DT
cord-256444-grw5s2pf	1150	31	gross	gross	JJ
cord-256444-grw5s2pf	1150	32	features	feature	NNS
cord-256444-grw5s2pf	1150	33	have	have	VBP
cord-256444-grw5s2pf	1150	34	recently	recently	RB
cord-256444-grw5s2pf	1150	35	been	be	VBN
cord-256444-grw5s2pf	1150	36	confirmed	confirm	VBN
cord-256444-grw5s2pf	1150	37	for	for	IN
cord-256444-grw5s2pf	1150	38	IBV	IBV	NNP
cord-256444-grw5s2pf	1150	39	,	,	,
cord-256444-grw5s2pf	1150	40	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1150	41	,	,	,
cord-256444-grw5s2pf	1150	42	and	and	CC
cord-256444-grw5s2pf	1150	43	FIPV	FIPV	NNS
cord-256444-grw5s2pf	1150	44	.	.	.
cord-256444-grw5s2pf	1151	1	Recently	recently	RB
cord-256444-grw5s2pf	1151	2	,	,	,
cord-256444-grw5s2pf	1151	3	an	an	DT
cord-256444-grw5s2pf	1151	4	ultrastructural	ultrastructural	JJ
cord-256444-grw5s2pf	1151	5	study	study	NN
cord-256444-grw5s2pf	1151	6	of	of	IN
cord-256444-grw5s2pf	1151	7	the	the	DT
cord-256444-grw5s2pf	1151	8	replication	replication	NN
cord-256444-grw5s2pf	1151	9	of	of	IN
cord-256444-grw5s2pf	1151	10	IBV	IBV	NNP
cord-256444-grw5s2pf	1151	11	in	in	IN
cord-256444-grw5s2pf	1151	12	renal	renal	JJ
cord-256444-grw5s2pf	1151	13	ductotubular	ductotubular	JJ
cord-256444-grw5s2pf	1151	14	epithelial	epithelial	JJ
cord-256444-grw5s2pf	1151	15	cells	cell	NNS
cord-256444-grw5s2pf	1151	16	of	of	IN
cord-256444-grw5s2pf	1151	17	infected	infected	JJ
cord-256444-grw5s2pf	1151	18	chicks	chick	NNS
cord-256444-grw5s2pf	1151	19	has	have	VBZ
cord-256444-grw5s2pf	1151	20	also	also	RB
cord-256444-grw5s2pf	1151	21	been	be	VBN
cord-256444-grw5s2pf	1151	22	very	very	RB
cord-256444-grw5s2pf	1151	23	informative	informative	JJ
cord-256444-grw5s2pf	1151	24	(	(	-LRB-
cord-256444-grw5s2pf	1151	25	Chen	Chen	NNP
cord-256444-grw5s2pf	1151	26	and	and	CC
cord-256444-grw5s2pf	1151	27	Itakura	Itakura	NNP
cord-256444-grw5s2pf	1151	28	,	,	,
cord-256444-grw5s2pf	1151	29	1996	1996	CD
cord-256444-grw5s2pf	1151	30	)	)	-RRB-
cord-256444-grw5s2pf	1151	31	.	.	.
cord-256444-grw5s2pf	1152	1	The	the	DT
cord-256444-grw5s2pf	1152	2	first	first	JJ
cord-256444-grw5s2pf	1152	3	virions	virion	NNS
cord-256444-grw5s2pf	1152	4	form	form	NN
cord-256444-grw5s2pf	1152	5	in	in	IN
cord-256444-grw5s2pf	1152	6	the	the	DT
cord-256444-grw5s2pf	1152	7	perinuclear	perinuclear	NNP
cord-256444-grw5s2pf	1152	8	region	region	NN
cord-256444-grw5s2pf	1152	9	,	,	,
cord-256444-grw5s2pf	1152	10	in	in	IN
cord-256444-grw5s2pf	1152	11	small	small	JJ
cord-256444-grw5s2pf	1152	12	,	,	,
cord-256444-grw5s2pf	1152	13	smooth	smooth	JJ
cord-256444-grw5s2pf	1152	14	vesicles/	vesicles/	POS
cord-256444-grw5s2pf	1152	15	tubules	tubule	NNS
cord-256444-grw5s2pf	1152	16	between	between	IN
cord-256444-grw5s2pf	1152	17	the	the	DT
cord-256444-grw5s2pf	1152	18	rough	rough	JJ
cord-256444-grw5s2pf	1152	19	ER	er	NN
cord-256444-grw5s2pf	1152	20	and	and	CC
cord-256444-grw5s2pf	1152	21	the	the	DT
cord-256444-grw5s2pf	1152	22	cis	cis	NNP
cord-256444-grw5s2pf	1152	23	side	side	NN
cord-256444-grw5s2pf	1152	24	of	of	IN
cord-256444-grw5s2pf	1152	25	the	the	DT
cord-256444-grw5s2pf	1152	26	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1152	27	stack	stack	NN
cord-256444-grw5s2pf	1152	28	.	.	.
cord-256444-grw5s2pf	1153	1	Later	later	RBR
cord-256444-grw5s2pf	1153	2	,	,	,
cord-256444-grw5s2pf	1153	3	the	the	DT
cord-256444-grw5s2pf	1153	4	rough	rough	JJ
cord-256444-grw5s2pf	1153	5	ER	er	NN
cord-256444-grw5s2pf	1153	6	becomes	become	VBZ
cord-256444-grw5s2pf	1153	7	the	the	DT
cord-256444-grw5s2pf	1153	8	major	major	JJ
cord-256444-grw5s2pf	1153	9	site	site	NN
cord-256444-grw5s2pf	1153	10	of	of	IN
cord-256444-grw5s2pf	1153	11	virion	virion	NN
cord-256444-grw5s2pf	1153	12	assembly	assembly	NN
cord-256444-grw5s2pf	1153	13	,	,	,
cord-256444-grw5s2pf	1153	14	extending	extend	VBG
cord-256444-grw5s2pf	1153	15	beyond	beyond	IN
cord-256444-grw5s2pf	1153	16	the	the	DT
cord-256444-grw5s2pf	1153	17	perinuclear	perinuclear	NNP
cord-256444-grw5s2pf	1153	18	region	region	NN
cord-256444-grw5s2pf	1153	19	.	.	.
cord-256444-grw5s2pf	1154	1	Virions	virion	NNS
cord-256444-grw5s2pf	1154	2	then	then	RB
cord-256444-grw5s2pf	1154	3	proceed	proceed	VBP
cord-256444-grw5s2pf	1154	4	through	through	IN
cord-256444-grw5s2pf	1154	5	the	the	DT
cord-256444-grw5s2pf	1154	6	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1154	7	complex	complex	NN
cord-256444-grw5s2pf	1154	8	,	,	,
cord-256444-grw5s2pf	1154	9	at	at	IN
cord-256444-grw5s2pf	1154	10	the	the	DT
cord-256444-grw5s2pf	1154	11	trans	trans	NNP
cord-256444-grw5s2pf	1154	12	side	side	NN
cord-256444-grw5s2pf	1154	13	of	of	IN
cord-256444-grw5s2pf	1154	14	which	which	WDT
cord-256444-grw5s2pf	1154	15	they	-PRON-	PRP
cord-256444-grw5s2pf	1154	16	are	be	VBP
cord-256444-grw5s2pf	1154	17	collected	collect	VBN
cord-256444-grw5s2pf	1154	18	into	into	IN
cord-256444-grw5s2pf	1154	19	vesicles	vesicle	NNS
cord-256444-grw5s2pf	1154	20	of	of	IN
cord-256444-grw5s2pf	1154	21	the	the	DT
cord-256444-grw5s2pf	1154	22	constitutive	constitutive	JJ
cord-256444-grw5s2pf	1154	23	exocytic	exocytic	JJ
cord-256444-grw5s2pf	1154	24	pathway	pathway	NN
cord-256444-grw5s2pf	1154	25	and	and	CC
cord-256444-grw5s2pf	1154	26	subsequently	subsequently	RB
cord-256444-grw5s2pf	1154	27	released	release	VBN
cord-256444-grw5s2pf	1154	28	from	from	IN
cord-256444-grw5s2pf	1154	29	the	the	DT
cord-256444-grw5s2pf	1154	30	cell	cell	NN
cord-256444-grw5s2pf	1154	31	.	.	.
cord-256444-grw5s2pf	1155	1	The	the	DT
cord-256444-grw5s2pf	1155	2	major	major	JJ
cord-256444-grw5s2pf	1155	3	determining	determining	NN
cord-256444-grw5s2pf	1155	4	factor	factor	NN
cord-256444-grw5s2pf	1155	5	for	for	IN
cord-256444-grw5s2pf	1155	6	the	the	DT
cord-256444-grw5s2pf	1155	7	site	site	NN
cord-256444-grw5s2pf	1155	8	of	of	IN
cord-256444-grw5s2pf	1155	9	virus	virus	NN
cord-256444-grw5s2pf	1155	10	assembly	assembly	NN
cord-256444-grw5s2pf	1155	11	appears	appear	VBZ
cord-256444-grw5s2pf	1155	12	to	to	TO
cord-256444-grw5s2pf	1155	13	be	be	VB
cord-256444-grw5s2pf	1155	14	the	the	DT
cord-256444-grw5s2pf	1155	15	site	site	NN
cord-256444-grw5s2pf	1155	16	of	of	IN
cord-256444-grw5s2pf	1155	17	localization	localization	NN
cord-256444-grw5s2pf	1155	18	of	of	IN
cord-256444-grw5s2pf	1155	19	the	the	DT
cord-256444-grw5s2pf	1155	20	M	M	NNP
cord-256444-grw5s2pf	1155	21	protein	protein	NN
cord-256444-grw5s2pf	1155	22	,	,	,
cord-256444-grw5s2pf	1155	23	which	which	WDT
cord-256444-grw5s2pf	1155	24	is	be	VBZ
cord-256444-grw5s2pf	1155	25	in	in	IN
cord-256444-grw5s2pf	1155	26	the	the	DT
cord-256444-grw5s2pf	1155	27	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1155	28	complex	complex	NN
cord-256444-grw5s2pf	1155	29	.	.	.
cord-256444-grw5s2pf	1156	1	There	there	EX
cord-256444-grw5s2pf	1156	2	are	be	VBP
cord-256444-grw5s2pf	1156	3	some	some	DT
cord-256444-grw5s2pf	1156	4	points	point	NNS
cord-256444-grw5s2pf	1156	5	of	of	IN
cord-256444-grw5s2pf	1156	6	difference	difference	NN
cord-256444-grw5s2pf	1156	7	among	among	IN
cord-256444-grw5s2pf	1156	8	the	the	DT
cord-256444-grw5s2pf	1156	9	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1156	10	.	.	.
cord-256444-grw5s2pf	1157	1	When	when	WRB
cord-256444-grw5s2pf	1157	2	the	the	DT
cord-256444-grw5s2pf	1157	3	M	M	NNP
cord-256444-grw5s2pf	1157	4	protein	protein	NN
cord-256444-grw5s2pf	1157	5	of	of	IN
cord-256444-grw5s2pf	1157	6	MHV	MHV	NNP
cord-256444-grw5s2pf	1157	7	was	be	VBD
cord-256444-grw5s2pf	1157	8	expressed	express	VBN
cord-256444-grw5s2pf	1157	9	,	,	,
cord-256444-grw5s2pf	1157	10	it	-PRON-	PRP
cord-256444-grw5s2pf	1157	11	accumulated	accumulate	VBD
cord-256444-grw5s2pf	1157	12	in	in	IN
cord-256444-grw5s2pf	1157	13	the	the	DT
cord-256444-grw5s2pf	1157	14	trans	trans	JJ
cord-256444-grw5s2pf	1157	15	-	-	NNP
cord-256444-grw5s2pf	1157	16	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1157	17	membranes	membrane	NNS
cord-256444-grw5s2pf	1157	18	,	,	,
cord-256444-grw5s2pf	1157	19	consistent	consistent	JJ
cord-256444-grw5s2pf	1157	20	with	with	IN
cord-256444-grw5s2pf	1157	21	its	-PRON-	PRP$
cord-256444-grw5s2pf	1157	22	O	o	NN
cord-256444-grw5s2pf	1157	23	-	-	HYPH
cord-256444-grw5s2pf	1157	24	linked	link	VBN
cord-256444-grw5s2pf	1157	25	glycosylation	glycosylation	NN
cord-256444-grw5s2pf	1157	26	,	,	,
cord-256444-grw5s2pf	1157	27	which	which	WDT
cord-256444-grw5s2pf	1157	28	occurs	occur	VBZ
cord-256444-grw5s2pf	1157	29	efficiently	efficiently	RB
cord-256444-grw5s2pf	1157	30	(	(	-LRB-
cord-256444-grw5s2pf	1157	31	Locker	Locker	NNP
cord-256444-grw5s2pf	1157	32	et	et	FW
cord-256444-grw5s2pf	1157	33	al	al	NNP
cord-256444-grw5s2pf	1157	34	.	.	NNP
cord-256444-grw5s2pf	1157	35	,	,	,
cord-256444-grw5s2pf	1157	36	1992a	1992a	CD
cord-256444-grw5s2pf	1157	37	;	;	:
cord-256444-grw5s2pf	1157	38	Klumperman	Klumperman	NNP
cord-256444-grw5s2pf	1157	39	et	et	FW
cord-256444-grw5s2pf	1157	40	al	al	NNP
cord-256444-grw5s2pf	1157	41	.	.	NNP
cord-256444-grw5s2pf	1157	42	,	,	,
cord-256444-grw5s2pf	1157	43	1994	1994	CD
cord-256444-grw5s2pf	1157	44	)	)	-RRB-
cord-256444-grw5s2pf	1157	45	.	.	.
cord-256444-grw5s2pf	1158	1	In	in	IN
cord-256444-grw5s2pf	1158	2	contrast	contrast	NN
cord-256444-grw5s2pf	1158	3	,	,	,
cord-256444-grw5s2pf	1158	4	expression	expression	NN
cord-256444-grw5s2pf	1158	5	of	of	IN
cord-256444-grw5s2pf	1158	6	the	the	DT
cord-256444-grw5s2pf	1158	7	IBV	IBV	NNP
cord-256444-grw5s2pf	1158	8	M	M	NNP
cord-256444-grw5s2pf	1158	9	protein	protein	NN
cord-256444-grw5s2pf	1158	10	from	from	IN
cord-256444-grw5s2pf	1158	11	cDNA	cdna	NN
cord-256444-grw5s2pf	1158	12	resulted	result	VBD
cord-256444-grw5s2pf	1158	13	in	in	IN
cord-256444-grw5s2pf	1158	14	its	-PRON-	PRP$
cord-256444-grw5s2pf	1158	15	accumulation	accumulation	NN
cord-256444-grw5s2pf	1158	16	in	in	IN
cord-256444-grw5s2pf	1158	17	cis	cis	NNP
cord-256444-grw5s2pf	1158	18	-	-	HYPH
cord-256444-grw5s2pf	1158	19	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1158	20	membranes	membrane	NNS
cord-256444-grw5s2pf	1158	21	;	;	:
cord-256444-grw5s2pf	1158	22	consequently	consequently	RB
cord-256444-grw5s2pf	1158	23	the	the	DT
cord-256444-grw5s2pf	1158	24	highmannose	highmannose	JJ
cord-256444-grw5s2pf	1158	25	N	n	CD
cord-256444-grw5s2pf	1158	26	-	-	HYPH
cord-256444-grw5s2pf	1158	27	linked	link	VBN
cord-256444-grw5s2pf	1158	28	glycans	glycan	NNS
cord-256444-grw5s2pf	1158	29	of	of	IN
cord-256444-grw5s2pf	1158	30	the	the	DT
cord-256444-grw5s2pf	1158	31	M	M	NNP
cord-256444-grw5s2pf	1158	32	protein	protein	NN
cord-256444-grw5s2pf	1158	33	were	be	VBD
cord-256444-grw5s2pf	1158	34	not	not	RB
cord-256444-grw5s2pf	1158	35	efficiently	efficiently	RB
cord-256444-grw5s2pf	1158	36	converted	convert	VBN
cord-256444-grw5s2pf	1158	37	to	to	IN
cord-256444-grw5s2pf	1158	38	complex	complex	JJ
cord-256444-grw5s2pf	1158	39	ones	one	NNS
cord-256444-grw5s2pf	1159	1	(	(	-LRB-
cord-256444-grw5s2pf	1159	2	Machamer	Machamer	NNP
cord-256444-grw5s2pf	1159	3	et	et	NNP
cord-256444-grw5s2pf	1159	4	al	al	NNP
cord-256444-grw5s2pf	1159	5	.	.	NNP
cord-256444-grw5s2pf	1159	6	,	,	,
cord-256444-grw5s2pf	1159	7	1990	1990	CD
cord-256444-grw5s2pf	1160	1	;	;	:
cord-256444-grw5s2pf	1160	2	Klumperman	Klumperman	NNP
cord-256444-grw5s2pf	1160	3	et	et	FW
cord-256444-grw5s2pf	1160	4	al	al	NNP
cord-256444-grw5s2pf	1160	5	.	.	NNP
cord-256444-grw5s2pf	1160	6	,	,	,
cord-256444-grw5s2pf	1160	7	1994	1994	CD
cord-256444-grw5s2pf	1160	8	)	)	-RRB-
cord-256444-grw5s2pf	1160	9	,	,	,
cord-256444-grw5s2pf	1160	10	in	in	IN
cord-256444-grw5s2pf	1160	11	agreement	agreement	NN
cord-256444-grw5s2pf	1160	12	with	with	IN
cord-256444-grw5s2pf	1160	13	the	the	DT
cord-256444-grw5s2pf	1160	14	properties	property	NNS
cord-256444-grw5s2pf	1160	15	of	of	IN
cord-256444-grw5s2pf	1160	16	the	the	DT
cord-256444-grw5s2pf	1160	17	M	M	NNP
cord-256444-grw5s2pf	1160	18	protein	protein	NN
cord-256444-grw5s2pf	1160	19	in	in	IN
cord-256444-grw5s2pf	1160	20	the	the	DT
cord-256444-grw5s2pf	1160	21	IBV	IBV	NNP
cord-256444-grw5s2pf	1160	22	virions	virion	NNS
cord-256444-grw5s2pf	1160	23	.	.	.
cord-256444-grw5s2pf	1161	1	Glycosylation	glycosylation	NN
cord-256444-grw5s2pf	1161	2	of	of	IN
cord-256444-grw5s2pf	1161	3	the	the	DT
cord-256444-grw5s2pf	1161	4	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1161	5	M	M	NNP
cord-256444-grw5s2pf	1161	6	protein	protein	NN
cord-256444-grw5s2pf	1161	7	is	be	VBZ
cord-256444-grw5s2pf	1161	8	not	not	RB
cord-256444-grw5s2pf	1161	9	essential	essential	JJ
cord-256444-grw5s2pf	1161	10	for	for	IN
cord-256444-grw5s2pf	1161	11	its	-PRON-	PRP$
cord-256444-grw5s2pf	1161	12	translocation	translocation	NN
cord-256444-grw5s2pf	1161	13	or	or	CC
cord-256444-grw5s2pf	1161	14	for	for	IN
cord-256444-grw5s2pf	1161	15	virus	virus	NN
cord-256444-grw5s2pf	1161	16	particle	particle	NN
cord-256444-grw5s2pf	1161	17	formation	formation	NN
cord-256444-grw5s2pf	1161	18	.	.	.
cord-256444-grw5s2pf	1162	1	The	the	DT
cord-256444-grw5s2pf	1162	2	M	M	NNP
cord-256444-grw5s2pf	1162	3	protein	protein	NN
cord-256444-grw5s2pf	1162	4	exists	exist	VBZ
cord-256444-grw5s2pf	1162	5	as	as	IN
cord-256444-grw5s2pf	1162	6	monomers	monomer	NNS
cord-256444-grw5s2pf	1162	7	in	in	IN
cord-256444-grw5s2pf	1162	8	the	the	DT
cord-256444-grw5s2pf	1162	9	ER	er	NN
cord-256444-grw5s2pf	1162	10	,	,	,
cord-256444-grw5s2pf	1162	11	but	but	CC
cord-256444-grw5s2pf	1162	12	it	-PRON-	PRP
cord-256444-grw5s2pf	1162	13	oligomerizes	oligomerize	VBZ
cord-256444-grw5s2pf	1162	14	to	to	TO
cord-256444-grw5s2pf	1162	15	form	form	VB
cord-256444-grw5s2pf	1162	16	variously	variously	RB
cord-256444-grw5s2pf	1162	17	sized	sized	JJ
cord-256444-grw5s2pf	1162	18	complexes	complex	NNS
cord-256444-grw5s2pf	1162	19	during	during	IN
cord-256444-grw5s2pf	1162	20	transport	transport	NN
cord-256444-grw5s2pf	1162	21	through	through	IN
cord-256444-grw5s2pf	1162	22	the	the	DT
cord-256444-grw5s2pf	1162	23	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1162	24	and	and	CC
cord-256444-grw5s2pf	1162	25	trans	trans	NNP
cord-256444-grw5s2pf	1162	26	-	-	JJ
cord-256444-grw5s2pf	1162	27	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1162	28	network	network	NN
cord-256444-grw5s2pf	1163	1	(	(	-LRB-
cord-256444-grw5s2pf	1163	2	Locker	Locker	NNP
cord-256444-grw5s2pf	1163	3	et	et	NNP
cord-256444-grw5s2pf	1163	4	al	al	NNP
cord-256444-grw5s2pf	1163	5	.	.	NNP
cord-256444-grw5s2pf	1163	6	,	,	,
cord-256444-grw5s2pf	1163	7	1995	1995	CD
cord-256444-grw5s2pf	1163	8	)	)	-RRB-
cord-256444-grw5s2pf	1163	9	.	.	.
cord-256444-grw5s2pf	1164	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1164	2	is	be	VBZ
cord-256444-grw5s2pf	1164	3	likely	likely	JJ
cord-256444-grw5s2pf	1164	4	that	that	IN
cord-256444-grw5s2pf	1164	5	the	the	DT
cord-256444-grw5s2pf	1164	6	M	M	NNP
cord-256444-grw5s2pf	1164	7	molecules	molecule	NNS
cord-256444-grw5s2pf	1164	8	in	in	IN
cord-256444-grw5s2pf	1164	9	the	the	DT
cord-256444-grw5s2pf	1164	10	virus	virus	NN
cord-256444-grw5s2pf	1164	11	particles	particle	NNS
cord-256444-grw5s2pf	1164	12	are	be	VBP
cord-256444-grw5s2pf	1164	13	in	in	IN
cord-256444-grw5s2pf	1164	14	complexed	complexed	JJ
cord-256444-grw5s2pf	1164	15	form	form	NN
cord-256444-grw5s2pf	1164	16	.	.	.
cord-256444-grw5s2pf	1165	1	The	the	DT
cord-256444-grw5s2pf	1165	2	sequence	sequence	NN
cord-256444-grw5s2pf	1165	3	requirements	requirement	VBZ
cord-256444-grw5s2pf	1165	4	for	for	IN
cord-256444-grw5s2pf	1165	5	insertion	insertion	NN
cord-256444-grw5s2pf	1165	6	of	of	IN
cord-256444-grw5s2pf	1165	7	the	the	DT
cord-256444-grw5s2pf	1165	8	nascent	nascent	JJ
cord-256444-grw5s2pf	1165	9	M	M	NNP
cord-256444-grw5s2pf	1165	10	polypeptide	polypeptide	NN
cord-256444-grw5s2pf	1165	11	into	into	IN
cord-256444-grw5s2pf	1165	12	the	the	DT
cord-256444-grw5s2pf	1165	13	rough	rough	JJ
cord-256444-grw5s2pf	1165	14	ER	er	NN
cord-256444-grw5s2pf	1165	15	have	have	VBP
cord-256444-grw5s2pf	1165	16	not	not	RB
cord-256444-grw5s2pf	1165	17	been	be	VBN
cord-256444-grw5s2pf	1165	18	precisely	precisely	RB
cord-256444-grw5s2pf	1165	19	defined	define	VBN
cord-256444-grw5s2pf	1165	20	.	.	.
cord-256444-grw5s2pf	1166	1	With	with	IN
cord-256444-grw5s2pf	1166	2	the	the	DT
cord-256444-grw5s2pf	1166	3	exception	exception	NN
cord-256444-grw5s2pf	1166	4	of	of	IN
cord-256444-grw5s2pf	1166	5	the	the	DT
cord-256444-grw5s2pf	1166	6	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1166	7	group	group	NN
cord-256444-grw5s2pf	1166	8	,	,	,
cord-256444-grw5s2pf	1166	9	the	the	DT
cord-256444-grw5s2pf	1166	10	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1166	11	M	m	CD
cord-256444-grw5s2pf	1166	12	proteins	protein	NNS
cord-256444-grw5s2pf	1166	13	do	do	VBP
cord-256444-grw5s2pf	1166	14	not	not	RB
cord-256444-grw5s2pf	1166	15	have	have	VB
cord-256444-grw5s2pf	1166	16	an	an	DT
cord-256444-grw5s2pf	1166	17	amino	amino	NN
cord-256444-grw5s2pf	1166	18	-	-	HYPH
cord-256444-grw5s2pf	1166	19	terminal	terminal	NN
cord-256444-grw5s2pf	1166	20	signal	signal	NN
cord-256444-grw5s2pf	1166	21	peptide	peptide	NN
cord-256444-grw5s2pf	1166	22	.	.	.
cord-256444-grw5s2pf	1167	1	Even	even	RB
cord-256444-grw5s2pf	1167	2	in	in	IN
cord-256444-grw5s2pf	1167	3	the	the	DT
cord-256444-grw5s2pf	1167	4	case	case	NN
cord-256444-grw5s2pf	1167	5	of	of	IN
cord-256444-grw5s2pf	1167	6	the	the	DT
cord-256444-grw5s2pf	1167	7	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1167	8	group	group	NN
cord-256444-grw5s2pf	1167	9	,	,	,
cord-256444-grw5s2pf	1167	10	the	the	DT
cord-256444-grw5s2pf	1167	11	signal	signal	NN
cord-256444-grw5s2pf	1167	12	peptide	peptide	NN
cord-256444-grw5s2pf	1167	13	is	be	VBZ
cord-256444-grw5s2pf	1167	14	not	not	RB
cord-256444-grw5s2pf	1167	15	essential	essential	JJ
cord-256444-grw5s2pf	1167	16	for	for	IN
cord-256444-grw5s2pf	1167	17	membrane	membrane	NN
cord-256444-grw5s2pf	1167	18	insertion	insertion	NN
cord-256444-grw5s2pf	1167	19	of	of	IN
cord-256444-grw5s2pf	1167	20	the	the	DT
cord-256444-grw5s2pf	1167	21	M	M	NNP
cord-256444-grw5s2pf	1167	22	protein	protein	NN
cord-256444-grw5s2pf	1167	23	(	(	-LRB-
cord-256444-grw5s2pf	1167	24	Kapke	Kapke	NNP
cord-256444-grw5s2pf	1167	25	et	et	NNP
cord-256444-grw5s2pf	1167	26	al	al	NNP
cord-256444-grw5s2pf	1167	27	.	.	NNP
cord-256444-grw5s2pf	1167	28	,	,	,
cord-256444-grw5s2pf	1167	29	1988	1988	CD
cord-256444-grw5s2pf	1167	30	;	;	:
cord-256444-grw5s2pf	1167	31	Vennema	Vennema	NNP
cord-256444-grw5s2pf	1167	32	et	et	FW
cord-256444-grw5s2pf	1167	33	al	al	NNP
cord-256444-grw5s2pf	1167	34	.	.	NNP
cord-256444-grw5s2pf	1167	35	,	,	,
cord-256444-grw5s2pf	1167	36	1991	1991	CD
cord-256444-grw5s2pf	1167	37	)	)	-RRB-
cord-256444-grw5s2pf	1167	38	.	.	.
cord-256444-grw5s2pf	1168	1	Rather	rather	RB
cord-256444-grw5s2pf	1168	2	,	,	,
cord-256444-grw5s2pf	1168	3	one	one	CD
cord-256444-grw5s2pf	1168	4	of	of	IN
cord-256444-grw5s2pf	1168	5	the	the	DT
cord-256444-grw5s2pf	1168	6	three	three	CD
cord-256444-grw5s2pf	1168	7	transmembrane	transmembrane	NN
cord-256444-grw5s2pf	1168	8	sequences	sequence	NNS
cord-256444-grw5s2pf	1168	9	of	of	IN
cord-256444-grw5s2pf	1168	10	the	the	DT
cord-256444-grw5s2pf	1168	11	M	M	NNP
cord-256444-grw5s2pf	1168	12	protein	protein	NN
cord-256444-grw5s2pf	1168	13	is	be	VBZ
cord-256444-grw5s2pf	1168	14	responsible	responsible	JJ
cord-256444-grw5s2pf	1168	15	for	for	IN
cord-256444-grw5s2pf	1168	16	the	the	DT
cord-256444-grw5s2pf	1168	17	insertion	insertion	NN
cord-256444-grw5s2pf	1168	18	of	of	IN
cord-256444-grw5s2pf	1168	19	M	M	NNP
cord-256444-grw5s2pf	1168	20	into	into	IN
cord-256444-grw5s2pf	1168	21	the	the	DT
cord-256444-grw5s2pf	1168	22	ER	ER	NNP
cord-256444-grw5s2pf	1168	23	and	and	CC
cord-256444-grw5s2pf	1168	24	its	-PRON-	PRP$
cord-256444-grw5s2pf	1168	25	final	final	JJ
cord-256444-grw5s2pf	1168	26	localization	localization	NN
cord-256444-grw5s2pf	1168	27	in	in	IN
cord-256444-grw5s2pf	1168	28	the	the	DT
cord-256444-grw5s2pf	1168	29	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1168	30	complex	complex	NN
cord-256444-grw5s2pf	1168	31	(	(	-LRB-
cord-256444-grw5s2pf	1168	32	Machamer	Machamer	NNP
cord-256444-grw5s2pf	1168	33	and	and	CC
cord-256444-grw5s2pf	1168	34	Rose	Rose	NNP
cord-256444-grw5s2pf	1168	35	,	,	,
cord-256444-grw5s2pf	1168	36	1987	1987	CD
cord-256444-grw5s2pf	1168	37	;	;	:
cord-256444-grw5s2pf	1168	38	Mayer	Mayer	NNP
cord-256444-grw5s2pf	1168	39	et	et	NNP
cord-256444-grw5s2pf	1168	40	al	al	NNP
cord-256444-grw5s2pf	1168	41	.	.	NNP
cord-256444-grw5s2pf	1168	42	,	,	,
cord-256444-grw5s2pf	1168	43	1988	1988	CD
cord-256444-grw5s2pf	1168	44	;	;	.
cord-256444-grw5s2pf	1169	1	Armstrong	Armstrong	NNP
cord-256444-grw5s2pf	1169	2	et	et	NNP
cord-256444-grw5s2pf	1169	3	al	al	NNP
cord-256444-grw5s2pf	1169	4	.	.	NNP
cord-256444-grw5s2pf	1169	5	,	,	,
cord-256444-grw5s2pf	1169	6	1990	1990	CD
cord-256444-grw5s2pf	1170	1	;	;	:
cord-256444-grw5s2pf	1170	2	Locker	Locker	NNP
cord-256444-grw5s2pf	1170	3	et	et	NNP
cord-256444-grw5s2pf	1170	4	al	al	NNP
cord-256444-grw5s2pf	1170	5	.	.	NNP
cord-256444-grw5s2pf	1170	6	,	,	,
cord-256444-grw5s2pf	1170	7	199213	199213	CD
cord-256444-grw5s2pf	1170	8	)	)	-RRB-
cord-256444-grw5s2pf	1170	9	.	.	.
cord-256444-grw5s2pf	1171	1	Different	different	JJ
cord-256444-grw5s2pf	1171	2	domains	domain	NNS
cord-256444-grw5s2pf	1171	3	of	of	IN
cord-256444-grw5s2pf	1171	4	the	the	DT
cord-256444-grw5s2pf	1171	5	M	M	NNP
cord-256444-grw5s2pf	1171	6	protein	protein	NN
cord-256444-grw5s2pf	1171	7	of	of	IN
cord-256444-grw5s2pf	1171	8	IBV	IBV	NNP
cord-256444-grw5s2pf	1171	9	and	and	CC
cord-256444-grw5s2pf	1171	10	MHV	MHV	NNP
cord-256444-grw5s2pf	1171	11	have	have	VBP
cord-256444-grw5s2pf	1171	12	been	be	VBN
cord-256444-grw5s2pf	1171	13	identified	identify	VBN
cord-256444-grw5s2pf	1171	14	as	as	IN
cord-256444-grw5s2pf	1171	15	the	the	DT
cord-256444-grw5s2pf	1171	16	sequences	sequence	NNS
cord-256444-grw5s2pf	1171	17	responsible	responsible	JJ
cord-256444-grw5s2pf	1171	18	for	for	IN
cord-256444-grw5s2pf	1171	19	the	the	DT
cord-256444-grw5s2pf	1171	20	final	final	JJ
cord-256444-grw5s2pf	1171	21	localization	localization	NN
cord-256444-grw5s2pf	1171	22	of	of	IN
cord-256444-grw5s2pf	1171	23	the	the	DT
cord-256444-grw5s2pf	1171	24	protein	protein	NN
cord-256444-grw5s2pf	1171	25	.	.	.
cord-256444-grw5s2pf	1172	1	The	the	DT
cord-256444-grw5s2pf	1172	2	first	first	JJ
cord-256444-grw5s2pf	1172	3	membrane	membrane	NN
cord-256444-grw5s2pf	1172	4	-	-	HYPH
cord-256444-grw5s2pf	1172	5	spanning	span	VBG
cord-256444-grw5s2pf	1172	6	domain	domain	NN
cord-256444-grw5s2pf	1172	7	of	of	IN
cord-256444-grw5s2pf	1172	8	the	the	DT
cord-256444-grw5s2pf	1172	9	IBV	IBV	NNP
cord-256444-grw5s2pf	1172	10	M	M	NNP
cord-256444-grw5s2pf	1172	11	protein	protein	NN
cord-256444-grw5s2pf	1172	12	performs	perform	VBZ
cord-256444-grw5s2pf	1172	13	this	this	DT
cord-256444-grw5s2pf	1172	14	function	function	NN
cord-256444-grw5s2pf	1172	15	,	,	,
cord-256444-grw5s2pf	1172	16	the	the	DT
cord-256444-grw5s2pf	1172	17	M	M	NNP
cord-256444-grw5s2pf	1172	18	protein	protein	NN
cord-256444-grw5s2pf	1172	19	being	be	VBG
cord-256444-grw5s2pf	1172	20	concentrated	concentrate	VBN
cord-256444-grw5s2pf	1172	21	in	in	IN
cord-256444-grw5s2pf	1172	22	the	the	DT
cord-256444-grw5s2pf	1172	23	cis	cis	NNP
cord-256444-grw5s2pf	1172	24	-	-	HYPH
cord-256444-grw5s2pf	1172	25	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1172	26	membranes	membrane	NNS
cord-256444-grw5s2pf	1172	27	(	(	-LRB-
cord-256444-grw5s2pf	1172	28	Machamer	Machamer	NNP
cord-256444-grw5s2pf	1172	29	and	and	CC
cord-256444-grw5s2pf	1172	30	Rose	Rose	NNP
cord-256444-grw5s2pf	1172	31	,	,	,
cord-256444-grw5s2pf	1172	32	1987	1987	CD
cord-256444-grw5s2pf	1172	33	;	;	:
cord-256444-grw5s2pf	1173	1	Machamer	Machamer	NNP
cord-256444-grw5s2pf	1173	2	et	et	NNP
cord-256444-grw5s2pf	1173	3	al	al	NNP
cord-256444-grw5s2pf	1173	4	.	.	NNP
cord-256444-grw5s2pf	1173	5	,	,	,
cord-256444-grw5s2pf	1174	1	1990	1990	CD
cord-256444-grw5s2pf	1174	2	Swift	Swift	NNP
cord-256444-grw5s2pf	1174	3	and	and	CC
cord-256444-grw5s2pf	1174	4	Machamer	Machamer	NNP
cord-256444-grw5s2pf	1174	5	,	,	,
cord-256444-grw5s2pf	1174	6	1991	1991	CD
cord-256444-grw5s2pf	1174	7	)	)	-RRB-
cord-256444-grw5s2pf	1174	8	.	.	.
cord-256444-grw5s2pf	1175	1	In	in	IN
cord-256444-grw5s2pf	1175	2	contrast	contrast	NN
cord-256444-grw5s2pf	1175	3	,	,	,
cord-256444-grw5s2pf	1175	4	the	the	DT
cord-256444-grw5s2pf	1175	5	carboxyterminal	carboxyterminal	JJ
cord-256444-grw5s2pf	1175	6	domain	domain	NN
cord-256444-grw5s2pf	1175	7	of	of	IN
cord-256444-grw5s2pf	1175	8	the	the	DT
cord-256444-grw5s2pf	1175	9	MHV	MHV	NNP
cord-256444-grw5s2pf	1175	10	M	M	NNP
cord-256444-grw5s2pf	1175	11	protein	protein	NN
cord-256444-grw5s2pf	1175	12	,	,	,
cord-256444-grw5s2pf	1175	13	probably	probably	RB
cord-256444-grw5s2pf	1175	14	in	in	IN
cord-256444-grw5s2pf	1175	15	combination	combination	NN
cord-256444-grw5s2pf	1175	16	with	with	IN
cord-256444-grw5s2pf	1175	17	a	a	DT
cord-256444-grw5s2pf	1175	18	middle	middle	JJ
cord-256444-grw5s2pf	1175	19	domain	domain	NN
cord-256444-grw5s2pf	1175	20	,	,	,
cord-256444-grw5s2pf	1175	21	directs	direct	VBZ
cord-256444-grw5s2pf	1175	22	the	the	DT
cord-256444-grw5s2pf	1175	23	protein	protein	NN
cord-256444-grw5s2pf	1175	24	to	to	IN
cord-256444-grw5s2pf	1175	25	the	the	DT
cord-256444-grw5s2pf	1175	26	trans	trans	NNP
cord-256444-grw5s2pf	1175	27	-	-	NNP
cord-256444-grw5s2pf	1175	28	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1175	29	(	(	-LRB-
cord-256444-grw5s2pf	1175	30	Armstrong	Armstrong	NNP
cord-256444-grw5s2pf	1175	31	and	and	CC
cord-256444-grw5s2pf	1175	32	Patel	Patel	NNP
cord-256444-grw5s2pf	1175	33	,	,	,
cord-256444-grw5s2pf	1175	34	1991	1991	CD
cord-256444-grw5s2pf	1175	35	;	;	:
cord-256444-grw5s2pf	1175	36	Weisz	Weisz	NNP
cord-256444-grw5s2pf	1175	37	et	et	NNP
cord-256444-grw5s2pf	1175	38	al	al	NNP
cord-256444-grw5s2pf	1175	39	.	.	NNP
cord-256444-grw5s2pf	1175	40	,	,	,
cord-256444-grw5s2pf	1175	41	1993	1993	CD
cord-256444-grw5s2pf	1175	42	;	;	:
cord-256444-grw5s2pf	1175	43	Krijnse	Krijnse	NNP
cord-256444-grw5s2pf	1175	44	-	-	HYPH
cord-256444-grw5s2pf	1175	45	Locker	Locker	NNP
cord-256444-grw5s2pf	1176	1	et	et	NNP
cord-256444-grw5s2pf	1176	2	al	al	NNP
cord-256444-grw5s2pf	1176	3	.	.	NNP
cord-256444-grw5s2pf	1176	4	,	,	,
cord-256444-grw5s2pf	1176	5	1994	1994	CD
cord-256444-grw5s2pf	1176	6	)	)	-RRB-
cord-256444-grw5s2pf	1176	7	.	.	.
cord-256444-grw5s2pf	1177	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1177	2	should	should	MD
cord-256444-grw5s2pf	1177	3	be	be	VB
cord-256444-grw5s2pf	1177	4	borne	bear	VBN
cord-256444-grw5s2pf	1177	5	in	in	IN
cord-256444-grw5s2pf	1177	6	mind	mind	NN
cord-256444-grw5s2pf	1177	7	,	,	,
cord-256444-grw5s2pf	1177	8	however	however	RB
cord-256444-grw5s2pf	1177	9	,	,	,
cord-256444-grw5s2pf	1177	10	that	that	IN
cord-256444-grw5s2pf	1177	11	the	the	DT
cord-256444-grw5s2pf	1177	12	major	major	JJ
cord-256444-grw5s2pf	1177	13	site	site	NN
cord-256444-grw5s2pf	1177	14	ofvirus	ofvirus	NN
cord-256444-grw5s2pf	1177	15	particle	particle	NN
cord-256444-grw5s2pf	1177	16	formation	formation	NN
cord-256444-grw5s2pf	1177	17	is	be	VBZ
cord-256444-grw5s2pf	1177	18	proximal	proximal	JJ
cord-256444-grw5s2pf	1177	19	to	to	IN
cord-256444-grw5s2pf	1177	20	either	either	DT
cord-256444-grw5s2pf	1177	21	of	of	IN
cord-256444-grw5s2pf	1177	22	the	the	DT
cord-256444-grw5s2pf	1177	23	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1177	24	compartments	compartment	NNS
cord-256444-grw5s2pf	1177	25	,	,	,
cord-256444-grw5s2pf	1177	26	namely	namely	RB
cord-256444-grw5s2pf	1177	27	,	,	,
cord-256444-grw5s2pf	1177	28	in	in	IN
cord-256444-grw5s2pf	1177	29	an	an	DT
cord-256444-grw5s2pf	1177	30	intermediate	intermediate	JJ
cord-256444-grw5s2pf	1177	31	compartment	compartment	NN
cord-256444-grw5s2pf	1177	32	between	between	IN
cord-256444-grw5s2pf	1177	33	the	the	DT
cord-256444-grw5s2pf	1177	34	ER	ER	NNP
cord-256444-grw5s2pf	1177	35	and	and	CC
cord-256444-grw5s2pf	1177	36	the	the	DT
cord-256444-grw5s2pf	1177	37	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1177	38	complex	complex	NN
cord-256444-grw5s2pf	1177	39	.	.	.
cord-256444-grw5s2pf	1178	1	Thus	thus	RB
cord-256444-grw5s2pf	1178	2	,	,	,
cord-256444-grw5s2pf	1178	3	it	-PRON-	PRP
cord-256444-grw5s2pf	1178	4	is	be	VBZ
cord-256444-grw5s2pf	1178	5	proximal	proximal	JJ
cord-256444-grw5s2pf	1178	6	to	to	IN
cord-256444-grw5s2pf	1178	7	the	the	DT
cord-256444-grw5s2pf	1178	8	major	major	JJ
cord-256444-grw5s2pf	1178	9	site	site	NN
cord-256444-grw5s2pf	1178	10	of	of	IN
cord-256444-grw5s2pf	1178	11	M	M	NNP
cord-256444-grw5s2pf	1178	12	accumulation	accumulation	NN
cord-256444-grw5s2pf	1178	13	.	.	.
cord-256444-grw5s2pf	1179	1	What	what	WP
cord-256444-grw5s2pf	1179	2	is	be	VBZ
cord-256444-grw5s2pf	1179	3	responsible	responsible	JJ
cord-256444-grw5s2pf	1179	4	for	for	IN
cord-256444-grw5s2pf	1179	5	that	that	DT
cord-256444-grw5s2pf	1179	6	?	?	.
cord-256444-grw5s2pf	1180	1	The	the	DT
cord-256444-grw5s2pf	1180	2	answer	answer	NN
cord-256444-grw5s2pf	1180	3	would	would	MD
cord-256444-grw5s2pf	1180	4	appear	appear	VB
cord-256444-grw5s2pf	1180	5	to	to	TO
cord-256444-grw5s2pf	1180	6	be	be	VB
cord-256444-grw5s2pf	1180	7	that	that	IN
cord-256444-grw5s2pf	1180	8	the	the	DT
cord-256444-grw5s2pf	1180	9	S	S	NNP
cord-256444-grw5s2pf	1180	10	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1180	11	and	and	CC
cord-256444-grw5s2pf	1180	12	the	the	DT
cord-256444-grw5s2pf	1180	13	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1180	14	interact	interact	VB
cord-256444-grw5s2pf	1180	15	with	with	IN
cord-256444-grw5s2pf	1180	16	the	the	DT
cord-256444-grw5s2pf	1180	17	M	M	NNP
cord-256444-grw5s2pf	1180	18	protein	protein	NN
cord-256444-grw5s2pf	1180	19	molecules	molecule	NNS
cord-256444-grw5s2pf	1180	20	before	before	IN
cord-256444-grw5s2pf	1180	21	the	the	DT
cord-256444-grw5s2pf	1180	22	M	M	NNP
cord-256444-grw5s2pf	1180	23	proteins	protein	NNS
cord-256444-grw5s2pf	1180	24	have	have	VBP
cord-256444-grw5s2pf	1180	25	migrated	migrate	VBN
cord-256444-grw5s2pf	1180	26	to	to	IN
cord-256444-grw5s2pf	1180	27	the	the	DT
cord-256444-grw5s2pf	1180	28	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1180	29	,	,	,
cord-256444-grw5s2pf	1180	30	precipitating	precipitate	VBG
cord-256444-grw5s2pf	1180	31	virus	virus	NN
cord-256444-grw5s2pf	1180	32	particle	particle	NN
cord-256444-grw5s2pf	1180	33	formation	formation	NN
cord-256444-grw5s2pf	1180	34	.	.	.
cord-256444-grw5s2pf	1181	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1181	2	has	have	VBZ
cord-256444-grw5s2pf	1181	3	been	be	VBN
cord-256444-grw5s2pf	1181	4	shown	show	VBN
cord-256444-grw5s2pf	1181	5	that	that	IN
cord-256444-grw5s2pf	1181	6	the	the	DT
cord-256444-grw5s2pf	1181	7	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1181	8	M	M	NNP
cord-256444-grw5s2pf	1181	9	protein	protein	NN
cord-256444-grw5s2pf	1181	10	can	can	MD
cord-256444-grw5s2pf	1181	11	interact	interact	VB
cord-256444-grw5s2pf	1181	12	with	with	IN
cord-256444-grw5s2pf	1181	13	nucleocapsids	nucleocapsid	NNS
cord-256444-grw5s2pf	1181	14	(	(	-LRB-
cord-256444-grw5s2pf	1181	15	Sturman	Sturman	NNP
cord-256444-grw5s2pf	1181	16	et	et	NNP
cord-256444-grw5s2pf	1181	17	al	al	NNP
cord-256444-grw5s2pf	1181	18	.	.	NNP
cord-256444-grw5s2pf	1181	19	,	,	,
cord-256444-grw5s2pf	1181	20	1980	1980	CD
cord-256444-grw5s2pf	1181	21	)	)	-RRB-
cord-256444-grw5s2pf	1181	22	.	.	.
cord-256444-grw5s2pf	1182	1	This	this	DT
cord-256444-grw5s2pf	1182	2	interaction	interaction	NN
cord-256444-grw5s2pf	1182	3	requires	require	VBZ
cord-256444-grw5s2pf	1182	4	the	the	DT
cord-256444-grw5s2pf	1182	5	presence	presence	NN
cord-256444-grw5s2pf	1182	6	of	of	IN
cord-256444-grw5s2pf	1182	7	viral	viral	JJ
cord-256444-grw5s2pf	1182	8	RNA	RNA	NNP
cord-256444-grw5s2pf	1182	9	,	,	,
cord-256444-grw5s2pf	1182	10	since	since	IN
cord-256444-grw5s2pf	1182	11	the	the	DT
cord-256444-grw5s2pf	1182	12	N	N	NNP
cord-256444-grw5s2pf	1182	13	protein	protein	NN
cord-256444-grw5s2pf	1182	14	alone	alone	RB
cord-256444-grw5s2pf	1182	15	can	can	MD
cord-256444-grw5s2pf	1182	16	not	not	RB
cord-256444-grw5s2pf	1182	17	be	be	VB
cord-256444-grw5s2pf	1182	18	incorporated	incorporate	VBN
cord-256444-grw5s2pf	1182	19	into	into	IN
cord-256444-grw5s2pf	1182	20	the	the	DT
cord-256444-grw5s2pf	1182	21	VLPs	vlp	NNS
cord-256444-grw5s2pf	1182	22	(	(	-LRB-
cord-256444-grw5s2pf	1182	23	Bos	Bos	NNP
cord-256444-grw5s2pf	1182	24	et	et	NNP
cord-256444-grw5s2pf	1182	25	al	al	NNP
cord-256444-grw5s2pf	1182	26	.	.	NNP
cord-256444-grw5s2pf	1182	27	,	,	,
cord-256444-grw5s2pf	1182	28	1996	1996	CD
cord-256444-grw5s2pf	1182	29	;	;	:
cord-256444-grw5s2pf	1182	30	Vennema	Vennema	NNP
cord-256444-grw5s2pf	1182	31	et	et	FW
cord-256444-grw5s2pf	1182	32	al	al	NNP
cord-256444-grw5s2pf	1182	33	.	.	NNP
cord-256444-grw5s2pf	1182	34	,	,	,
cord-256444-grw5s2pf	1182	35	19961	19961	CD
cord-256444-grw5s2pf	1182	36	,	,	,
cord-256444-grw5s2pf	1182	37	suggesting	suggest	VBG
cord-256444-grw5s2pf	1182	38	either	either	CC
cord-256444-grw5s2pf	1182	39	that	that	IN
cord-256444-grw5s2pf	1182	40	M	M	NNP
cord-256444-grw5s2pf	1182	41	interacts	interact	VBZ
cord-256444-grw5s2pf	1182	42	with	with	IN
cord-256444-grw5s2pf	1182	43	viral	viral	JJ
cord-256444-grw5s2pf	1182	44	RNA	RNA	NNP
cord-256444-grw5s2pf	1182	45	,	,	,
cord-256444-grw5s2pf	1182	46	or	or	CC
cord-256444-grw5s2pf	1182	47	that	that	IN
cord-256444-grw5s2pf	1182	48	RNA	RNA	NNP
cord-256444-grw5s2pf	1182	49	-	-	HYPH
cord-256444-grw5s2pf	1182	50	N	N	NNP
cord-256444-grw5s2pf	1182	51	protein	protein	NN
cord-256444-grw5s2pf	1182	52	binding	binding	NN
cord-256444-grw5s2pf	1182	53	induces	induce	VBZ
cord-256444-grw5s2pf	1182	54	a	a	DT
cord-256444-grw5s2pf	1182	55	conformational	conformational	JJ
cord-256444-grw5s2pf	1182	56	change	change	NN
cord-256444-grw5s2pf	1182	57	in	in	IN
cord-256444-grw5s2pf	1182	58	the	the	DT
cord-256444-grw5s2pf	1182	59	N	N	NNP
cord-256444-grw5s2pf	1182	60	protein	protein	NN
cord-256444-grw5s2pf	1182	61	,	,	,
cord-256444-grw5s2pf	1182	62	enabling	enable	VBG
cord-256444-grw5s2pf	1182	63	it	-PRON-	PRP
cord-256444-grw5s2pf	1182	64	to	to	TO
cord-256444-grw5s2pf	1182	65	interact	interact	VB
cord-256444-grw5s2pf	1182	66	with	with	IN
cord-256444-grw5s2pf	1182	67	M.	M.	NNP
cord-256444-grw5s2pf	1182	68	Interaction	Interaction	NNP
cord-256444-grw5s2pf	1182	69	between	between	IN
cord-256444-grw5s2pf	1182	70	the	the	DT
cord-256444-grw5s2pf	1182	71	M	M	NNP
cord-256444-grw5s2pf	1182	72	and	and	CC
cord-256444-grw5s2pf	1182	73	S	S	NNP
cord-256444-grw5s2pf	1182	74	proteins	protein	NNS
cord-256444-grw5s2pf	1182	75	has	have	VBZ
cord-256444-grw5s2pf	1182	76	also	also	RB
cord-256444-grw5s2pf	1182	77	been	be	VBN
cord-256444-grw5s2pf	1182	78	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	1182	79	.	.	.
cord-256444-grw5s2pf	1183	1	The	the	DT
cord-256444-grw5s2pf	1183	2	M	M	NNP
cord-256444-grw5s2pf	1183	3	and	and	CC
cord-256444-grw5s2pf	1183	4	S	S	NNP
cord-256444-grw5s2pf	1183	5	proteins	protein	NNS
cord-256444-grw5s2pf	1183	6	co	co	NN
cord-256444-grw5s2pf	1183	7	-	-	NN
cord-256444-grw5s2pf	1183	8	sediment	sediment	NN
cord-256444-grw5s2pf	1183	9	under	under	IN
cord-256444-grw5s2pf	1183	10	certain	certain	JJ
cord-256444-grw5s2pf	1183	11	ionic	ionic	JJ
cord-256444-grw5s2pf	1183	12	conditions	condition	NNS
cord-256444-grw5s2pf	1183	13	after	after	IN
cord-256444-grw5s2pf	1183	14	dissolution	dissolution	NN
cord-256444-grw5s2pf	1183	15	of	of	IN
cord-256444-grw5s2pf	1183	16	virions	virion	NNS
cord-256444-grw5s2pf	1183	17	with	with	IN
cord-256444-grw5s2pf	1183	18	mild	mild	JJ
cord-256444-grw5s2pf	1183	19	detergents	detergent	NNS
cord-256444-grw5s2pf	1183	20	(	(	-LRB-
cord-256444-grw5s2pf	1183	21	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	1183	22	,	,	,
cord-256444-grw5s2pf	1183	23	1983b	1983b	CD
cord-256444-grw5s2pf	1183	24	)	)	-RRB-
cord-256444-grw5s2pf	1183	25	,	,	,
cord-256444-grw5s2pf	1183	26	and	and	CC
cord-256444-grw5s2pf	1183	27	cell	cell	NN
cord-256444-grw5s2pf	1183	28	-	-	HYPH
cord-256444-grw5s2pf	1183	29	associated	associate	VBN
cord-256444-grw5s2pf	1183	30	complexes	complex	NNS
cord-256444-grw5s2pf	1183	31	containing	contain	VBG
cord-256444-grw5s2pf	1183	32	M	M	NNP
cord-256444-grw5s2pf	1183	33	and	and	CC
cord-256444-grw5s2pf	1183	34	S	S	NNP
cord-256444-grw5s2pf	1183	35	have	have	VBP
cord-256444-grw5s2pf	1183	36	been	be	VBN
cord-256444-grw5s2pf	1183	37	detected	detect	VBN
cord-256444-grw5s2pf	1183	38	(	(	-LRB-
cord-256444-grw5s2pf	1183	39	Opsteltenet	Opsteltenet	NNP
cord-256444-grw5s2pf	1183	40	al	al	NNP
cord-256444-grw5s2pf	1183	41	.	.	NNP
cord-256444-grw5s2pf	1183	42	,	,	,
cord-256444-grw5s2pf	1183	43	1995	1995	CD
cord-256444-grw5s2pf	1183	44	)	)	-RRB-
cord-256444-grw5s2pf	1183	45	.	.	.
cord-256444-grw5s2pf	1184	1	The	the	DT
cord-256444-grw5s2pf	1184	2	S	S	NNP
cord-256444-grw5s2pf	1184	3	protein	protein	NN
cord-256444-grw5s2pf	1184	4	undergoes	undergo	VBZ
cord-256444-grw5s2pf	1184	5	certain	certain	JJ
cord-256444-grw5s2pf	1184	6	conformational	conformational	JJ
cord-256444-grw5s2pf	1184	7	changes	change	NNS
cord-256444-grw5s2pf	1184	8	induced	induce	VBN
cord-256444-grw5s2pf	1184	9	by	by	IN
cord-256444-grw5s2pf	1184	10	disulfide	disulfide	JJ
cord-256444-grw5s2pf	1184	11	linkage	linkage	NN
cord-256444-grw5s2pf	1184	12	before	before	IN
cord-256444-grw5s2pf	1184	13	it	-PRON-	PRP
cord-256444-grw5s2pf	1184	14	is	be	VBZ
cord-256444-grw5s2pf	1184	15	able	able	JJ
cord-256444-grw5s2pf	1184	16	to	to	TO
cord-256444-grw5s2pf	1184	17	interact	interact	VB
cord-256444-grw5s2pf	1184	18	with	with	IN
cord-256444-grw5s2pf	1184	19	M	M	NNP
cord-256444-grw5s2pf	1184	20	(	(	-LRB-
cord-256444-grw5s2pf	1184	21	Opstelten	Opstelten	NNP
cord-256444-grw5s2pf	1184	22	et	et	NNP
cord-256444-grw5s2pf	1184	23	al	al	NNP
cord-256444-grw5s2pf	1184	24	.	.	NNP
cord-256444-grw5s2pf	1184	25	,	,	,
cord-256444-grw5s2pf	1184	26	1993	1993	CD
cord-256444-grw5s2pf	1184	27	.	.	.
cord-256444-grw5s2pf	1185	1	Inhibition	inhibition	NN
cord-256444-grw5s2pf	1185	2	of	of	IN
cord-256444-grw5s2pf	1185	3	correct	correct	JJ
cord-256444-grw5s2pf	1185	4	oligomerization	oligomerization	NN
cord-256444-grw5s2pf	1185	5	of	of	IN
cord-256444-grw5s2pf	1185	6	S	S	NNP
cord-256444-grw5s2pf	1185	7	by	by	IN
cord-256444-grw5s2pf	1185	8	dithiothreitol	dithiothreitol	NNP
cord-256444-grw5s2pf	1185	9	prevented	prevent	VBD
cord-256444-grw5s2pf	1185	10	interaction	interaction	NN
cord-256444-grw5s2pf	1185	11	of	of	IN
cord-256444-grw5s2pf	1185	12	S	S	NNP
cord-256444-grw5s2pf	1185	13	with	with	IN
cord-256444-grw5s2pf	1185	14	M	M	NNP
cord-256444-grw5s2pf	1185	15	and	and	CC
cord-256444-grw5s2pf	1185	16	,	,	,
cord-256444-grw5s2pf	1185	17	as	as	IN
cord-256444-grw5s2pf	1185	18	a	a	DT
cord-256444-grw5s2pf	1185	19	result	result	NN
cord-256444-grw5s2pf	1185	20	,	,	,
cord-256444-grw5s2pf	1185	21	the	the	DT
cord-256444-grw5s2pf	1185	22	rate	rate	NN
cord-256444-grw5s2pf	1185	23	of	of	IN
cord-256444-grw5s2pf	1185	24	transport	transport	NN
cord-256444-grw5s2pf	1185	25	of	of	IN
cord-256444-grw5s2pf	1185	26	the	the	DT
cord-256444-grw5s2pf	1185	27	M	M	NNP
cord-256444-grw5s2pf	1185	28	protein	protein	NN
cord-256444-grw5s2pf	1185	29	to	to	IN
cord-256444-grw5s2pf	1185	30	the	the	DT
cord-256444-grw5s2pf	1185	31	trans	trans	NNP
cord-256444-grw5s2pf	1185	32	-	-	NNP
cord-256444-grw5s2pf	1185	33	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1185	34	increased	increase	VBD
cord-256444-grw5s2pf	1185	35	(	(	-LRB-
cord-256444-grw5s2pf	1185	36	Opstelten	Opstelten	NNP
cord-256444-grw5s2pf	1185	37	et	et	NNP
cord-256444-grw5s2pf	1185	38	al	al	NNP
cord-256444-grw5s2pf	1185	39	.	.	NNP
cord-256444-grw5s2pf	1185	40	,	,	,
cord-256444-grw5s2pf	1185	41	1993	1993	CD
cord-256444-grw5s2pf	1185	42	)	)	-RRB-
cord-256444-grw5s2pf	1185	43	.	.	.
cord-256444-grw5s2pf	1186	1	This	this	DT
cord-256444-grw5s2pf	1186	2	result	result	NN
cord-256444-grw5s2pf	1186	3	suggests	suggest	VBZ
cord-256444-grw5s2pf	1186	4	that	that	IN
cord-256444-grw5s2pf	1186	5	S	S	NNP
cord-256444-grw5s2pf	1186	6	-	-	HYPH
cord-256444-grw5s2pf	1186	7	M	M	NNP
cord-256444-grw5s2pf	1186	8	interaction	interaction	NN
cord-256444-grw5s2pf	1186	9	can	can	MD
cord-256444-grw5s2pf	1186	10	retard	retard	VB
cord-256444-grw5s2pf	1186	11	the	the	DT
cord-256444-grw5s2pf	1186	12	transport	transport	NN
cord-256444-grw5s2pf	1186	13	of	of	IN
cord-256444-grw5s2pf	1186	14	the	the	DT
cord-256444-grw5s2pf	1186	15	M	M	NNP
cord-256444-grw5s2pf	1186	16	protein	protein	NN
cord-256444-grw5s2pf	1186	17	.	.	.
cord-256444-grw5s2pf	1187	1	The	the	DT
cord-256444-grw5s2pf	1187	2	ability	ability	NN
cord-256444-grw5s2pf	1187	3	of	of	IN
cord-256444-grw5s2pf	1187	4	the	the	DT
cord-256444-grw5s2pf	1187	5	S	S	NNP
cord-256444-grw5s2pf	1187	6	or	or	CC
cord-256444-grw5s2pf	1187	7	HE	HE	NNP
cord-256444-grw5s2pf	1187	8	protein	protein	NN
cord-256444-grw5s2pf	1187	9	to	to	TO
cord-256444-grw5s2pf	1187	10	interact	interact	VB
cord-256444-grw5s2pf	1187	11	with	with	IN
cord-256444-grw5s2pf	1187	12	the	the	DT
cord-256444-grw5s2pf	1187	13	M	M	NNP
cord-256444-grw5s2pf	1187	14	protein	protein	NN
cord-256444-grw5s2pf	1187	15	appears	appear	VBZ
cord-256444-grw5s2pf	1187	16	to	to	TO
cord-256444-grw5s2pf	1187	17	be	be	VB
cord-256444-grw5s2pf	1187	18	a	a	DT
cord-256444-grw5s2pf	1187	19	prerequisite	prerequisite	NN
cord-256444-grw5s2pf	1187	20	for	for	IN
cord-256444-grw5s2pf	1187	21	their	-PRON-	PRP$
cord-256444-grw5s2pf	1187	22	incorporation	incorporation	NN
cord-256444-grw5s2pf	1187	23	into	into	IN
cord-256444-grw5s2pf	1187	24	virus	virus	NN
cord-256444-grw5s2pf	1187	25	particles	particle	NNS
cord-256444-grw5s2pf	1187	26	.	.	.
cord-256444-grw5s2pf	1188	1	In	in	IN
cord-256444-grw5s2pf	1188	2	this	this	DT
cord-256444-grw5s2pf	1188	3	regard	regard	NN
cord-256444-grw5s2pf	1188	4	,	,	,
cord-256444-grw5s2pf	1188	5	it	-PRON-	PRP
cord-256444-grw5s2pf	1188	6	is	be	VBZ
cord-256444-grw5s2pf	1188	7	interesting	interesting	JJ
cord-256444-grw5s2pf	1188	8	to	to	TO
cord-256444-grw5s2pf	1188	9	note	note	VB
cord-256444-grw5s2pf	1188	10	that	that	IN
cord-256444-grw5s2pf	1188	11	MHV	MHV	NNP
cord-256444-grw5s2pf	1188	12	ts	ts	NN
cord-256444-grw5s2pf	1188	13	mutants	mutant	NNS
cord-256444-grw5s2pf	1188	14	with	with	IN
cord-256444-grw5s2pf	1188	15	a	a	DT
cord-256444-grw5s2pf	1188	16	deletion	deletion	NN
cord-256444-grw5s2pf	1188	17	in	in	IN
cord-256444-grw5s2pf	1188	18	the	the	DT
cord-256444-grw5s2pf	1188	19	ectodomain	ectodomain	NN
cord-256444-grw5s2pf	1188	20	of	of	IN
cord-256444-grw5s2pf	1188	21	the	the	DT
cord-256444-grw5s2pf	1188	22	S	S	NNP
cord-256444-grw5s2pf	1188	23	protein	protein	NN
cord-256444-grw5s2pf	1188	24	or	or	CC
cord-256444-grw5s2pf	1188	25	those	those	DT
cord-256444-grw5s2pf	1188	26	with	with	IN
cord-256444-grw5s2pf	1188	27	defects	defect	NNS
cord-256444-grw5s2pf	1188	28	in	in	IN
cord-256444-grw5s2pf	1188	29	oligomerization	oligomerization	NN
cord-256444-grw5s2pf	1188	30	of	of	IN
cord-256444-grw5s2pf	1188	31	the	the	DT
cord-256444-grw5s2pf	1188	32	S	S	NNP
cord-256444-grw5s2pf	1188	33	protein	protein	NN
cord-256444-grw5s2pf	1188	34	do	do	VBP
cord-256444-grw5s2pf	1188	35	not	not	RB
cord-256444-grw5s2pf	1188	36	incorporate	incorporate	VB
cord-256444-grw5s2pf	1188	37	the	the	DT
cord-256444-grw5s2pf	1188	38	S	S	NNP
cord-256444-grw5s2pf	1188	39	protein	protein	NN
cord-256444-grw5s2pf	1188	40	(	(	-LRB-
cord-256444-grw5s2pf	1188	41	Ricard	Ricard	NNP
cord-256444-grw5s2pf	1188	42	et	et	NNP
cord-256444-grw5s2pf	1188	43	al	al	NNP
cord-256444-grw5s2pf	1188	44	.	.	NNP
cord-256444-grw5s2pf	1188	45	,	,	,
cord-256444-grw5s2pf	1188	46	1995	1995	CD
cord-256444-grw5s2pf	1188	47	;	;	:
cord-256444-grw5s2pf	1188	48	Luytjes	Luytjes	NNP
cord-256444-grw5s2pf	1188	49	et	et	NNP
cord-256444-grw5s2pf	1188	50	al	al	NNP
cord-256444-grw5s2pf	1188	51	.	.	NNP
cord-256444-grw5s2pf	1188	52	,	,	,
cord-256444-grw5s2pf	1188	53	1997	1997	CD
cord-256444-grw5s2pf	1188	54	)	)	-RRB-
cord-256444-grw5s2pf	1188	55	.	.	.
cord-256444-grw5s2pf	1189	1	Also	also	RB
cord-256444-grw5s2pf	1189	2	,	,	,
cord-256444-grw5s2pf	1189	3	partial	partial	JJ
cord-256444-grw5s2pf	1189	4	deletions	deletion	NNS
cord-256444-grw5s2pf	1189	5	in	in	IN
cord-256444-grw5s2pf	1189	6	the	the	DT
cord-256444-grw5s2pf	1189	7	ectodomain	ectodomain	NN
cord-256444-grw5s2pf	1189	8	of	of	IN
cord-256444-grw5s2pf	1189	9	the	the	DT
cord-256444-grw5s2pf	1189	10	HE	HE	NNP
cord-256444-grw5s2pf	1189	11	protein	protein	NN
cord-256444-grw5s2pf	1189	12	prevent	prevent	VB
cord-256444-grw5s2pf	1189	13	its	-PRON-	PRP$
cord-256444-grw5s2pf	1189	14	incorporation	incorporation	NN
cord-256444-grw5s2pf	1189	15	into	into	IN
cord-256444-grw5s2pf	1189	16	virus	virus	NN
cord-256444-grw5s2pf	1189	17	particles	particle	NNS
cord-256444-grw5s2pf	1189	18	.	.	.
cord-256444-grw5s2pf	1190	1	These	these	DT
cord-256444-grw5s2pf	1190	2	results	result	NNS
cord-256444-grw5s2pf	1190	3	suggest	suggest	VBP
cord-256444-grw5s2pf	1190	4	that	that	IN
cord-256444-grw5s2pf	1190	5	the	the	DT
cord-256444-grw5s2pf	1190	6	interaction	interaction	NN
cord-256444-grw5s2pf	1190	7	of	of	IN
cord-256444-grw5s2pf	1190	8	S	S	NNP
cord-256444-grw5s2pf	1190	9	or	or	CC
cord-256444-grw5s2pf	1190	10	HE	HE	NNP
cord-256444-grw5s2pf	1190	11	with	with	IN
cord-256444-grw5s2pf	1190	12	M	M	NNP
cord-256444-grw5s2pf	1190	13	occurs	occur	VBZ
cord-256444-grw5s2pf	1190	14	through	through	IN
cord-256444-grw5s2pf	1190	15	the	the	DT
cord-256444-grw5s2pf	1190	16	ectodomain	ectodomain	NN
cord-256444-grw5s2pf	1190	17	or	or	CC
cord-256444-grw5s2pf	1190	18	requires	require	VBZ
cord-256444-grw5s2pf	1190	19	the	the	DT
cord-256444-grw5s2pf	1190	20	correct	correct	JJ
cord-256444-grw5s2pf	1190	21	protein	protein	NN
cord-256444-grw5s2pf	1190	22	conformation	conformation	NN
cord-256444-grw5s2pf	1190	23	in	in	IN
cord-256444-grw5s2pf	1190	24	the	the	DT
cord-256444-grw5s2pf	1190	25	ectodomain	ectodomain	NN
cord-256444-grw5s2pf	1190	26	.	.	.
cord-256444-grw5s2pf	1191	1	The	the	DT
cord-256444-grw5s2pf	1191	2	formation	formation	NN
cord-256444-grw5s2pf	1191	3	of	of	IN
cord-256444-grw5s2pf	1191	4	the	the	DT
cord-256444-grw5s2pf	1191	5	S	S	NNP
cord-256444-grw5s2pf	1191	6	-	-	HYPH
cord-256444-grw5s2pf	1191	7	M	M	NNP
cord-256444-grw5s2pf	1191	8	complex	complex	NN
cord-256444-grw5s2pf	1191	9	occurs	occur	VBZ
cord-256444-grw5s2pf	1191	10	in	in	IN
cord-256444-grw5s2pf	1191	11	the	the	DT
cord-256444-grw5s2pf	1191	12	pre	pre	JJ
cord-256444-grw5s2pf	1191	13	-	-	JJ
cord-256444-grw5s2pf	1191	14	Golgi	golgi	JJ
cord-256444-grw5s2pf	1191	15	complex	complex	NN
cord-256444-grw5s2pf	1191	16	,	,	,
cord-256444-grw5s2pf	1191	17	whereas	whereas	IN
cord-256444-grw5s2pf	1191	18	the	the	DT
cord-256444-grw5s2pf	1191	19	S	S	NNP
cord-256444-grw5s2pf	1191	20	-	-	HYPH
cord-256444-grw5s2pf	1191	21	M	M	NNP
cord-256444-grw5s2pf	1191	22	complex	complex	NN
cord-256444-grw5s2pf	1191	23	progresses	progress	VBZ
cord-256444-grw5s2pf	1191	24	until	until	IN
cord-256444-grw5s2pf	1191	25	the	the	DT
cord-256444-grw5s2pf	1191	26	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1191	27	complex	complex	NN
cord-256444-grw5s2pf	1191	28	,	,	,
cord-256444-grw5s2pf	1191	29	indicating	indicate	VBG
cord-256444-grw5s2pf	1191	30	that	that	IN
cord-256444-grw5s2pf	1191	31	this	this	DT
cord-256444-grw5s2pf	1191	32	interaction	interaction	NN
cord-256444-grw5s2pf	1191	33	is	be	VBZ
cord-256444-grw5s2pf	1191	34	not	not	RB
cord-256444-grw5s2pf	1191	35	sufficient	sufficient	JJ
cord-256444-grw5s2pf	1191	36	to	to	TO
cord-256444-grw5s2pf	1191	37	localize	localize	VB
cord-256444-grw5s2pf	1191	38	it	-PRON-	PRP
cord-256444-grw5s2pf	1191	39	in	in	IN
cord-256444-grw5s2pf	1191	40	the	the	DT
cord-256444-grw5s2pf	1191	41	pre	pre	JJ
cord-256444-grw5s2pf	1191	42	-	-	JJ
cord-256444-grw5s2pf	1191	43	Golgi	golgi	JJ
cord-256444-grw5s2pf	1191	44	complex	complex	NN
cord-256444-grw5s2pf	1191	45	,	,	,
cord-256444-grw5s2pf	1191	46	the	the	DT
cord-256444-grw5s2pf	1191	47	ultimate	ultimate	JJ
cord-256444-grw5s2pf	1191	48	site	site	NN
cord-256444-grw5s2pf	1191	49	of	of	IN
cord-256444-grw5s2pf	1191	50	virion	virion	NN
cord-256444-grw5s2pf	1191	51	budding	bud	VBG
cord-256444-grw5s2pf	1191	52	.	.	.
cord-256444-grw5s2pf	1192	1	Thus	thus	RB
cord-256444-grw5s2pf	1192	2	,	,	,
cord-256444-grw5s2pf	1192	3	M	M	NNP
cord-256444-grw5s2pf	1192	4	-	-	HYPH
cord-256444-grw5s2pf	1192	5	nucleocapsid	nucleocapsid	NNP
cord-256444-grw5s2pf	1192	6	interaction	interaction	NN
cord-256444-grw5s2pf	1192	7	may	may	MD
cord-256444-grw5s2pf	1192	8	also	also	RB
cord-256444-grw5s2pf	1192	9	contribute	contribute	VB
cord-256444-grw5s2pf	1192	10	to	to	IN
cord-256444-grw5s2pf	1192	11	the	the	DT
cord-256444-grw5s2pf	1192	12	determination	determination	NN
cord-256444-grw5s2pf	1192	13	of	of	IN
cord-256444-grw5s2pf	1192	14	the	the	DT
cord-256444-grw5s2pf	1192	15	site	site	NN
cord-256444-grw5s2pf	1192	16	of	of	IN
cord-256444-grw5s2pf	1192	17	virus	virus	NN
cord-256444-grw5s2pf	1192	18	assembly	assembly	NN
cord-256444-grw5s2pf	1192	19	.	.	.
cord-256444-grw5s2pf	1193	1	In	in	IN
cord-256444-grw5s2pf	1193	2	this	this	DT
cord-256444-grw5s2pf	1193	3	regard	regard	NN
cord-256444-grw5s2pf	1193	4	,	,	,
cord-256444-grw5s2pf	1193	5	it	-PRON-	PRP
cord-256444-grw5s2pf	1193	6	is	be	VBZ
cord-256444-grw5s2pf	1193	7	important	important	JJ
cord-256444-grw5s2pf	1193	8	to	to	TO
cord-256444-grw5s2pf	1193	9	note	note	VB
cord-256444-grw5s2pf	1193	10	that	that	IN
cord-256444-grw5s2pf	1193	11	the	the	DT
cord-256444-grw5s2pf	1193	12	recent	recent	JJ
cord-256444-grw5s2pf	1193	13	discovery	discovery	NN
cord-256444-grw5s2pf	1193	14	that	that	WDT
cord-256444-grw5s2pf	1193	15	M	M	NNP
cord-256444-grw5s2pf	1193	16	is	be	VBZ
cord-256444-grw5s2pf	1193	17	present	present	JJ
cord-256444-grw5s2pf	1193	18	in	in	IN
cord-256444-grw5s2pf	1193	19	the	the	DT
cord-256444-grw5s2pf	1193	20	viral	viral	JJ
cord-256444-grw5s2pf	1193	21	RNP	RNP	NNP
cord-256444-grw5s2pf	1193	22	core	core	NN
cord-256444-grw5s2pf	1193	23	,	,	,
cord-256444-grw5s2pf	1193	24	as	as	RB
cord-256444-grw5s2pf	1193	25	well	well	RB
cord-256444-grw5s2pf	1193	26	as	as	IN
cord-256444-grw5s2pf	1193	27	in	in	IN
cord-256444-grw5s2pf	1193	28	the	the	DT
cord-256444-grw5s2pf	1193	29	envelope	envelope	NN
cord-256444-grw5s2pf	1193	30	(	(	-LRB-
cord-256444-grw5s2pf	1193	31	Risco	Risco	NNP
cord-256444-grw5s2pf	1193	32	et	et	NNP
cord-256444-grw5s2pf	1193	33	al	al	NNP
cord-256444-grw5s2pf	1193	34	.	.	NNP
cord-256444-grw5s2pf	1193	35	,	,	,
cord-256444-grw5s2pf	1193	36	1996	1996	CD
cord-256444-grw5s2pf	1193	37	)	)	-RRB-
cord-256444-grw5s2pf	1193	38	may	may	MD
cord-256444-grw5s2pf	1193	39	further	further	RB
cord-256444-grw5s2pf	1193	40	indicate	indicate	VB
cord-256444-grw5s2pf	1193	41	the	the	DT
cord-256444-grw5s2pf	1193	42	crucial	crucial	JJ
cord-256444-grw5s2pf	1193	43	role	role	NN
cord-256444-grw5s2pf	1193	44	of	of	IN
cord-256444-grw5s2pf	1193	45	the	the	DT
cord-256444-grw5s2pf	1193	46	M	M	NNP
cord-256444-grw5s2pf	1193	47	protein	protein	NN
cord-256444-grw5s2pf	1193	48	in	in	IN
cord-256444-grw5s2pf	1193	49	the	the	DT
cord-256444-grw5s2pf	1193	50	virus	virus	NN
cord-256444-grw5s2pf	1193	51	assembly	assembly	NN
cord-256444-grw5s2pf	1193	52	process	process	NN
cord-256444-grw5s2pf	1193	53	.	.	.
cord-256444-grw5s2pf	1194	1	Only	only	RB
cord-256444-grw5s2pf	1194	2	the	the	DT
cord-256444-grw5s2pf	1194	3	M	M	NNP
cord-256444-grw5s2pf	1194	4	and	and	CC
cord-256444-grw5s2pf	1194	5	E	e	NN
cord-256444-grw5s2pf	1194	6	proteins	protein	NNS
cord-256444-grw5s2pf	1194	7	are	be	VBP
cord-256444-grw5s2pf	1194	8	required	require	VBN
cord-256444-grw5s2pf	1194	9	for	for	IN
cord-256444-grw5s2pf	1194	10	the	the	DT
cord-256444-grw5s2pf	1194	11	production	production	NN
cord-256444-grw5s2pf	1194	12	of	of	IN
cord-256444-grw5s2pf	1194	13	VLPs	vlp	NNS
cord-256444-grw5s2pf	1194	14	(	(	-LRB-
cord-256444-grw5s2pf	1194	15	Bos	Bos	NNP
cord-256444-grw5s2pf	1194	16	et	et	NNP
cord-256444-grw5s2pf	1194	17	al	al	NNP
cord-256444-grw5s2pf	1194	18	.	.	NNP
cord-256444-grw5s2pf	1194	19	,	,	,
cord-256444-grw5s2pf	1194	20	1996	1996	CD
cord-256444-grw5s2pf	1194	21	;	;	:
cord-256444-grw5s2pf	1194	22	Vennema	Vennema	NNP
cord-256444-grw5s2pf	1194	23	et	et	FW
cord-256444-grw5s2pf	1194	24	al	al	NNP
cord-256444-grw5s2pf	1194	25	.	.	NNP
cord-256444-grw5s2pf	1194	26	,	,	,
cord-256444-grw5s2pf	1194	27	1996	1996	CD
cord-256444-grw5s2pf	1194	28	)	)	-RRB-
cord-256444-grw5s2pf	1194	29	.	.	.
cord-256444-grw5s2pf	1195	1	These	these	DT
cord-256444-grw5s2pf	1195	2	particles	particle	NNS
cord-256444-grw5s2pf	1195	3	were	be	VBD
cord-256444-grw5s2pf	1195	4	formed	form	VBN
cord-256444-grw5s2pf	1195	5	when	when	WRB
cord-256444-grw5s2pf	1195	6	the	the	DT
cord-256444-grw5s2pf	1195	7	M	M	NNP
cord-256444-grw5s2pf	1195	8	and	and	CC
cord-256444-grw5s2pf	1195	9	E	e	NN
cord-256444-grw5s2pf	1195	10	proteins	protein	NNS
cord-256444-grw5s2pf	1195	11	were	be	VBD
cord-256444-grw5s2pf	1195	12	expressed	express	VBN
cord-256444-grw5s2pf	1195	13	from	from	IN
cord-256444-grw5s2pf	1195	14	transfected	transfecte	VBN
cord-256444-grw5s2pf	1195	15	plasmids	plasmid	NNS
cord-256444-grw5s2pf	1195	16	.	.	.
cord-256444-grw5s2pf	1196	1	S	S	NNP
cord-256444-grw5s2pf	1196	2	protein	protein	NN
cord-256444-grw5s2pf	1196	3	was	be	VBD
cord-256444-grw5s2pf	1196	4	incorporated	incorporate	VBN
cord-256444-grw5s2pf	1196	5	into	into	IN
cord-256444-grw5s2pf	1196	6	the	the	DT
cord-256444-grw5s2pf	1196	7	VLPs	vlp	NNS
cord-256444-grw5s2pf	1196	8	if	if	IN
cord-256444-grw5s2pf	1196	9	expressed	express	VBN
cord-256444-grw5s2pf	1196	10	.	.	.
cord-256444-grw5s2pf	1197	1	In	in	IN
cord-256444-grw5s2pf	1197	2	the	the	DT
cord-256444-grw5s2pf	1197	3	absence	absence	NN
cord-256444-grw5s2pf	1197	4	of	of	IN
cord-256444-grw5s2pf	1197	5	viral	viral	JJ
cord-256444-grw5s2pf	1197	6	RNA	RNA	NNP
cord-256444-grw5s2pf	1197	7	,	,	,
cord-256444-grw5s2pf	1197	8	the	the	DT
cord-256444-grw5s2pf	1197	9	N	N	NNP
cord-256444-grw5s2pf	1197	10	protein	protein	NN
cord-256444-grw5s2pf	1197	11	also	also	RB
cord-256444-grw5s2pf	1197	12	was	be	VBD
cord-256444-grw5s2pf	1197	13	not	not	RB
cord-256444-grw5s2pf	1197	14	incorporated	incorporate	VBN
cord-256444-grw5s2pf	1197	15	.	.	.
cord-256444-grw5s2pf	1198	1	When	when	WRB
cord-256444-grw5s2pf	1198	2	all	all	PDT
cord-256444-grw5s2pf	1198	3	the	the	DT
cord-256444-grw5s2pf	1198	4	structural	structural	JJ
cord-256444-grw5s2pf	1198	5	proteins	protein	NNS
cord-256444-grw5s2pf	1198	6	were	be	VBD
cord-256444-grw5s2pf	1198	7	expressed	express	VBN
cord-256444-grw5s2pf	1198	8	from	from	IN
cord-256444-grw5s2pf	1198	9	plasmids	plasmid	NNS
cord-256444-grw5s2pf	1198	10	in	in	IN
cord-256444-grw5s2pf	1198	11	the	the	DT
cord-256444-grw5s2pf	1198	12	presence	presence	NN
cord-256444-grw5s2pf	1198	13	of	of	IN
cord-256444-grw5s2pf	1198	14	an	an	DT
cord-256444-grw5s2pf	1198	15	MHV	MHV	NNP
cord-256444-grw5s2pf	1198	16	DI	DI	NNP
cord-256444-grw5s2pf	1198	17	RNA	RNA	NNP
cord-256444-grw5s2pf	1198	18	,	,	,
cord-256444-grw5s2pf	1198	19	which	which	WDT
cord-256444-grw5s2pf	1198	20	contains	contain	VBZ
cord-256444-grw5s2pf	1198	21	a	a	DT
cord-256444-grw5s2pf	1198	22	packaging	packaging	NN
cord-256444-grw5s2pf	1198	23	signal	signal	NN
cord-256444-grw5s2pf	1198	24	,	,	,
cord-256444-grw5s2pf	1198	25	and	and	CC
cord-256444-grw5s2pf	1198	26	in	in	IN
cord-256444-grw5s2pf	1198	27	the	the	DT
cord-256444-grw5s2pf	1198	28	absence	absence	NN
cord-256444-grw5s2pf	1198	29	of	of	IN
cord-256444-grw5s2pf	1198	30	helper	helper	NN
cord-256444-grw5s2pf	1198	31	virus	virus	NN
cord-256444-grw5s2pf	1198	32	,	,	,
cord-256444-grw5s2pf	1198	33	the	the	DT
cord-256444-grw5s2pf	1198	34	VLPs	vlp	NNS
cord-256444-grw5s2pf	1198	35	contained	contain	VBD
cord-256444-grw5s2pf	1198	36	the	the	DT
cord-256444-grw5s2pf	1198	37	DI	DI	NNP
cord-256444-grw5s2pf	1198	38	RNA	RNA	NNP
cord-256444-grw5s2pf	1198	39	(	(	-LRB-
cord-256444-grw5s2pf	1198	40	Bos	Bos	NNP
cord-256444-grw5s2pf	1198	41	et	et	NNP
cord-256444-grw5s2pf	1198	42	al	al	NNP
cord-256444-grw5s2pf	1198	43	.	.	NNP
cord-256444-grw5s2pf	1198	44	,	,	,
cord-256444-grw5s2pf	1198	45	1996	1996	CD
cord-256444-grw5s2pf	1198	46	)	)	-RRB-
cord-256444-grw5s2pf	1198	47	.	.	.
cord-256444-grw5s2pf	1199	1	Moreover	moreover	RB
cord-256444-grw5s2pf	1199	2	,	,	,
cord-256444-grw5s2pf	1199	3	these	these	DT
cord-256444-grw5s2pf	1199	4	VLP	VLP	NNP
cord-256444-grw5s2pf	1199	5	were	be	VBD
cord-256444-grw5s2pf	1199	6	"	"	``
cord-256444-grw5s2pf	1199	7	infectious	infectious	JJ
cord-256444-grw5s2pf	1199	8	,	,	,
cord-256444-grw5s2pf	1199	9	"	"	''
cord-256444-grw5s2pf	1199	10	i.e.	i.e.	FW
cord-256444-grw5s2pf	1199	11	,	,	,
cord-256444-grw5s2pf	1199	12	on	on	IN
cord-256444-grw5s2pf	1199	13	transfer	transfer	NN
cord-256444-grw5s2pf	1199	14	of	of	IN
cord-256444-grw5s2pf	1199	15	the	the	DT
cord-256444-grw5s2pf	1199	16	released	release	VBN
cord-256444-grw5s2pf	1199	17	VLPs	vlp	NNS
cord-256444-grw5s2pf	1199	18	to	to	IN
cord-256444-grw5s2pf	1199	19	a	a	DT
cord-256444-grw5s2pf	1199	20	new	new	JJ
cord-256444-grw5s2pf	1199	21	cell	cell	NN
cord-256444-grw5s2pf	1199	22	culture	culture	NN
cord-256444-grw5s2pf	1199	23	,	,	,
cord-256444-grw5s2pf	1199	24	they	-PRON-	PRP
cord-256444-grw5s2pf	1199	25	were	be	VBD
cord-256444-grw5s2pf	1199	26	able	able	JJ
cord-256444-grw5s2pf	1199	27	to	to	TO
cord-256444-grw5s2pf	1199	28	infect	infect	VB
cord-256444-grw5s2pf	1199	29	the	the	DT
cord-256444-grw5s2pf	1199	30	cells	cell	NNS
cord-256444-grw5s2pf	1199	31	,	,	,
cord-256444-grw5s2pf	1199	32	as	as	IN
cord-256444-grw5s2pf	1199	33	revealed	reveal	VBN
cord-256444-grw5s2pf	1199	34	by	by	IN
cord-256444-grw5s2pf	1199	35	the	the	DT
cord-256444-grw5s2pf	1199	36	rescue	rescue	NN
cord-256444-grw5s2pf	1199	37	of	of	IN
cord-256444-grw5s2pf	1199	38	the	the	DT
cord-256444-grw5s2pf	1199	39	DI	DI	NNP
cord-256444-grw5s2pf	1199	40	RNA	RNA	NNP
cord-256444-grw5s2pf	1199	41	by	by	IN
cord-256444-grw5s2pf	1199	42	helper	helper	NN
cord-256444-grw5s2pf	1199	43	virus	virus	NN
cord-256444-grw5s2pf	1199	44	.	.	.
cord-256444-grw5s2pf	1200	1	These	these	DT
cord-256444-grw5s2pf	1200	2	results	result	NNS
cord-256444-grw5s2pf	1200	3	show	show	VBP
cord-256444-grw5s2pf	1200	4	that	that	IN
cord-256444-grw5s2pf	1200	5	N	N	NNP
cord-256444-grw5s2pf	1200	6	is	be	VBZ
cord-256444-grw5s2pf	1200	7	dispensable	dispensable	JJ
cord-256444-grw5s2pf	1200	8	for	for	IN
cord-256444-grw5s2pf	1200	9	the	the	DT
cord-256444-grw5s2pf	1200	10	formation	formation	NN
cord-256444-grw5s2pf	1200	11	of	of	IN
cord-256444-grw5s2pf	1200	12	VLPs	vlp	NNS
cord-256444-grw5s2pf	1200	13	but	but	CC
cord-256444-grw5s2pf	1200	14	the	the	DT
cord-256444-grw5s2pf	1200	15	packaging	packaging	NN
cord-256444-grw5s2pf	1200	16	of	of	IN
cord-256444-grw5s2pf	1200	17	RNA	RNA	NNP
cord-256444-grw5s2pf	1200	18	into	into	IN
cord-256444-grw5s2pf	1200	19	virion	virion	NN
cord-256444-grw5s2pf	1200	20	requires	require	VBZ
cord-256444-grw5s2pf	1200	21	an	an	DT
cord-256444-grw5s2pf	1200	22	interaction	interaction	NN
cord-256444-grw5s2pf	1200	23	between	between	IN
cord-256444-grw5s2pf	1200	24	M	M	NNP
cord-256444-grw5s2pf	1200	25	and	and	CC
cord-256444-grw5s2pf	1200	26	the	the	DT
cord-256444-grw5s2pf	1200	27	N	N	NNP
cord-256444-grw5s2pf	1200	28	-	-	HYPH
cord-256444-grw5s2pf	1200	29	containing	contain	VBG
cord-256444-grw5s2pf	1200	30	ribonucleoprotein	ribonucleoprotein	NN
cord-256444-grw5s2pf	1200	31	,	,	,
cord-256444-grw5s2pf	1200	32	as	as	IN
cord-256444-grw5s2pf	1200	33	previously	previously	RB
cord-256444-grw5s2pf	1200	34	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	1200	35	(	(	-LRB-
cord-256444-grw5s2pf	1200	36	Sturman	Sturman	NNP
cord-256444-grw5s2pf	1200	37	et	et	NNP
cord-256444-grw5s2pf	1200	38	al	al	NNP
cord-256444-grw5s2pf	1200	39	.	.	NNP
cord-256444-grw5s2pf	1200	40	,	,	,
cord-256444-grw5s2pf	1200	41	1980	1980	CD
cord-256444-grw5s2pf	1200	42	)	)	-RRB-
cord-256444-grw5s2pf	1200	43	.	.	.
cord-256444-grw5s2pf	1201	1	The	the	DT
cord-256444-grw5s2pf	1201	2	expression	expression	NN
cord-256444-grw5s2pf	1201	3	of	of	IN
cord-256444-grw5s2pf	1201	4	the	the	DT
cord-256444-grw5s2pf	1201	5	M	M	NNP
cord-256444-grw5s2pf	1201	6	protein	protein	NN
cord-256444-grw5s2pf	1201	7	alone	alone	RB
cord-256444-grw5s2pf	1201	8	in	in	IN
cord-256444-grw5s2pf	1201	9	the	the	DT
cord-256444-grw5s2pf	1201	10	cells	cell	NNS
cord-256444-grw5s2pf	1201	11	did	do	VBD
cord-256444-grw5s2pf	1201	12	not	not	RB
cord-256444-grw5s2pf	1201	13	lead	lead	VB
cord-256444-grw5s2pf	1201	14	to	to	IN
cord-256444-grw5s2pf	1201	15	VLP	VLP	NNP
cord-256444-grw5s2pf	1201	16	formation	formation	NN
cord-256444-grw5s2pf	1201	17	or	or	CC
cord-256444-grw5s2pf	1201	18	induction	induction	NN
cord-256444-grw5s2pf	1201	19	of	of	IN
cord-256444-grw5s2pf	1201	20	curvature	curvature	NN
cord-256444-grw5s2pf	1201	21	in	in	IN
cord-256444-grw5s2pf	1201	22	the	the	DT
cord-256444-grw5s2pf	1201	23	M	M	NNP
cord-256444-grw5s2pf	1201	24	-	-	HYPH
cord-256444-grw5s2pf	1201	25	containing	contain	VBG
cord-256444-grw5s2pf	1201	26	intracellular	intracellular	JJ
cord-256444-grw5s2pf	1201	27	membranes	membrane	NNS
cord-256444-grw5s2pf	1201	28	.	.	.
cord-256444-grw5s2pf	1202	1	The	the	DT
cord-256444-grw5s2pf	1202	2	presence	presence	NN
cord-256444-grw5s2pf	1202	3	of	of	IN
cord-256444-grw5s2pf	1202	4	the	the	DT
cord-256444-grw5s2pf	1202	5	E	e	NN
cord-256444-grw5s2pf	1202	6	protein	protein	NN
cord-256444-grw5s2pf	1202	7	together	together	RB
cord-256444-grw5s2pf	1202	8	with	with	IN
cord-256444-grw5s2pf	1202	9	the	the	DT
cord-256444-grw5s2pf	1202	10	M	M	NNP
cord-256444-grw5s2pf	1202	11	protein	protein	NN
cord-256444-grw5s2pf	1202	12	triggered	trigger	VBD
cord-256444-grw5s2pf	1202	13	both	both	DT
cord-256444-grw5s2pf	1202	14	events	event	NNS
cord-256444-grw5s2pf	1202	15	,	,	,
cord-256444-grw5s2pf	1202	16	but	but	CC
cord-256444-grw5s2pf	1202	17	the	the	DT
cord-256444-grw5s2pf	1202	18	ratio	ratio	NN
cord-256444-grw5s2pf	1202	19	of	of	IN
cord-256444-grw5s2pf	1202	20	M	M	NNP
cord-256444-grw5s2pf	1202	21	:	:	:
cord-256444-grw5s2pf	1202	22	E	e	NN
cord-256444-grw5s2pf	1202	23	in	in	IN
cord-256444-grw5s2pf	1202	24	virions	virion	NNS
cord-256444-grw5s2pf	1202	25	was	be	VBD
cord-256444-grw5s2pf	1202	26	as	as	RB
cord-256444-grw5s2pf	1202	27	high	high	JJ
cord-256444-grw5s2pf	1202	28	as	as	IN
cord-256444-grw5s2pf	1202	29	1OO	1oo	CD
cord-256444-grw5s2pf	1202	30	:	:	:
cord-256444-grw5s2pf	1203	1	l	l	LS
cord-256444-grw5s2pf	1203	2	(	(	-LRB-
cord-256444-grw5s2pf	1203	3	Vennema	Vennema	NNP
cord-256444-grw5s2pf	1203	4	et	et	FW
cord-256444-grw5s2pf	1203	5	al	al	NNP
cord-256444-grw5s2pf	1203	6	.	.	NNP
cord-256444-grw5s2pf	1203	7	,	,	,
cord-256444-grw5s2pf	1203	8	1996	1996	CD
cord-256444-grw5s2pf	1203	9	)	)	-RRB-
cord-256444-grw5s2pf	1203	10	.	.	.
cord-256444-grw5s2pf	1204	1	This	this	DT
cord-256444-grw5s2pf	1204	2	has	have	VBZ
cord-256444-grw5s2pf	1204	3	led	lead	VBN
cord-256444-grw5s2pf	1204	4	to	to	IN
cord-256444-grw5s2pf	1204	5	the	the	DT
cord-256444-grw5s2pf	1204	6	suggestion	suggestion	NN
cord-256444-grw5s2pf	1204	7	that	that	IN
cord-256444-grw5s2pf	1204	8	E	e	NN
cord-256444-grw5s2pf	1204	9	does	do	VBZ
cord-256444-grw5s2pf	1204	10	not	not	RB
cord-256444-grw5s2pf	1204	11	have	have	VB
cord-256444-grw5s2pf	1204	12	frequent	frequent	JJ
cord-256444-grw5s2pf	1204	13	,	,	,
cord-256444-grw5s2pf	1204	14	regular	regular	JJ
cord-256444-grw5s2pf	1204	15	positions	position	NNS
cord-256444-grw5s2pf	1204	16	in	in	IN
cord-256444-grw5s2pf	1204	17	the	the	DT
cord-256444-grw5s2pf	1204	18	lattice	lattice	NN
cord-256444-grw5s2pf	1204	19	formed	form	VBN
cord-256444-grw5s2pf	1204	20	by	by	IN
cord-256444-grw5s2pf	1204	21	M	M	NNP
cord-256444-grw5s2pf	1204	22	but	but	CC
cord-256444-grw5s2pf	1204	23	rather	rather	RB
cord-256444-grw5s2pf	1204	24	occupies	occupy	VBZ
cord-256444-grw5s2pf	1204	25	strategic	strategic	JJ
cord-256444-grw5s2pf	1204	26	positions	position	NNS
cord-256444-grw5s2pf	1204	27	within	within	IN
cord-256444-grw5s2pf	1204	28	the	the	DT
cord-256444-grw5s2pf	1204	29	lattice	lattice	NN
cord-256444-grw5s2pf	1204	30	to	to	TO
cord-256444-grw5s2pf	1204	31	cause	cause	VB
cord-256444-grw5s2pf	1204	32	membrane	membrane	NN
cord-256444-grw5s2pf	1204	33	curvature	curvature	NN
cord-256444-grw5s2pf	1204	34	.	.	.
cord-256444-grw5s2pf	1205	1	Alternatively	alternatively	RB
cord-256444-grw5s2pf	1205	2	,	,	,
cord-256444-grw5s2pf	1205	3	its	-PRON-	PRP$
cord-256444-grw5s2pf	1205	4	role	role	NN
cord-256444-grw5s2pf	1205	5	may	may	MD
cord-256444-grw5s2pf	1205	6	be	be	VB
cord-256444-grw5s2pf	1205	7	to	to	TO
cord-256444-grw5s2pf	1205	8	close	close	VB
cord-256444-grw5s2pf	1205	9	the	the	DT
cord-256444-grw5s2pf	1205	10	neck	neck	NN
cord-256444-grw5s2pf	1205	11	of	of	IN
cord-256444-grw5s2pf	1205	12	the	the	DT
cord-256444-grw5s2pf	1205	13	virus	virus	NN
cord-256444-grw5s2pf	1205	14	particle	particle	NN
cord-256444-grw5s2pf	1205	15	as	as	IN
cord-256444-grw5s2pf	1205	16	it	-PRON-	PRP
cord-256444-grw5s2pf	1205	17	pinches	pinch	VBZ
cord-256444-grw5s2pf	1205	18	off	off	RP
cord-256444-grw5s2pf	1205	19	from	from	IN
cord-256444-grw5s2pf	1205	20	the	the	DT
cord-256444-grw5s2pf	1205	21	membrane	membrane	NN
cord-256444-grw5s2pf	1205	22	in	in	IN
cord-256444-grw5s2pf	1205	23	the	the	DT
cord-256444-grw5s2pf	1205	24	final	final	JJ
cord-256444-grw5s2pf	1205	25	stage	stage	NN
cord-256444-grw5s2pf	1205	26	of	of	IN
cord-256444-grw5s2pf	1205	27	budding	bud	VBG
cord-256444-grw5s2pf	1205	28	.	.	.
cord-256444-grw5s2pf	1206	1	What	what	WP
cord-256444-grw5s2pf	1206	2	determines	determine	VBZ
cord-256444-grw5s2pf	1206	3	the	the	DT
cord-256444-grw5s2pf	1206	4	site	site	NN
cord-256444-grw5s2pf	1206	5	of	of	IN
cord-256444-grw5s2pf	1206	6	virion	virion	NN
cord-256444-grw5s2pf	1206	7	budding	bud	VBG
cord-256444-grw5s2pf	1206	8	?	?	.
cord-256444-grw5s2pf	1207	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1207	2	is	be	VBZ
cord-256444-grw5s2pf	1207	3	possible	possible	JJ
cord-256444-grw5s2pf	1207	4	that	that	IN
cord-256444-grw5s2pf	1207	5	the	the	DT
cord-256444-grw5s2pf	1207	6	E	e	NN
cord-256444-grw5s2pf	1207	7	protein	protein	NN
cord-256444-grw5s2pf	1207	8	dictates	dictate	VBZ
cord-256444-grw5s2pf	1207	9	the	the	DT
cord-256444-grw5s2pf	1207	10	site	site	NN
cord-256444-grw5s2pf	1207	11	of	of	IN
cord-256444-grw5s2pf	1207	12	budding	bud	VBG
cord-256444-grw5s2pf	1207	13	,	,	,
cord-256444-grw5s2pf	1207	14	since	since	IN
cord-256444-grw5s2pf	1207	15	this	this	DT
cord-256444-grw5s2pf	1207	16	protein	protein	NN
cord-256444-grw5s2pf	1207	17	is	be	VBZ
cord-256444-grw5s2pf	1207	18	also	also	RB
cord-256444-grw5s2pf	1207	19	localized	localize	VBN
cord-256444-grw5s2pf	1207	20	in	in	IN
cord-256444-grw5s2pf	1207	21	the	the	DT
cord-256444-grw5s2pf	1207	22	perinuclear	perinuclear	NNP
cord-256444-grw5s2pf	1207	23	region	region	NN
cord-256444-grw5s2pf	1207	24	and	and	CC
cord-256444-grw5s2pf	1207	25	associated	associate	VBN
cord-256444-grw5s2pf	1207	26	with	with	IN
cord-256444-grw5s2pf	1207	27	membrane	membrane	NN
cord-256444-grw5s2pf	1207	28	(	(	-LRB-
cord-256444-grw5s2pf	1208	1	Godet	Godet	NNP
cord-256444-grw5s2pf	1208	2	et	et	NNP
cord-256444-grw5s2pf	1208	3	al	al	NNP
cord-256444-grw5s2pf	1208	4	.	.	.
cord-256444-grw5s2pf	1209	1	,	,	,
cord-256444-grw5s2pf	1209	2	1992	1992	CD
cord-256444-grw5s2pf	1209	3	;	;	:
cord-256444-grw5s2pf	1209	4	Yu	Yu	NNP
cord-256444-grw5s2pf	1209	5	et	et	NNP
cord-256444-grw5s2pf	1209	6	al	al	NNP
cord-256444-grw5s2pf	1209	7	.	.	NNP
cord-256444-grw5s2pf	1209	8	,	,	,
cord-256444-grw5s2pf	1209	9	1994	1994	CD
cord-256444-grw5s2pf	1209	10	)	)	-RRB-
cord-256444-grw5s2pf	1209	11	.	.	.
cord-256444-grw5s2pf	1210	1	Alternatively	alternatively	RB
cord-256444-grw5s2pf	1210	2	,	,	,
cord-256444-grw5s2pf	1210	3	it	-PRON-	PRP
cord-256444-grw5s2pf	1210	4	may	may	MD
cord-256444-grw5s2pf	1210	5	be	be	VB
cord-256444-grw5s2pf	1210	6	the	the	DT
cord-256444-grw5s2pf	1210	7	interaction	interaction	NN
cord-256444-grw5s2pf	1210	8	of	of	IN
cord-256444-grw5s2pf	1210	9	the	the	DT
cord-256444-grw5s2pf	1210	10	RNP	RNP	NNP
cord-256444-grw5s2pf	1210	11	-	-	HYPH
cord-256444-grw5s2pf	1210	12	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1210	13	with	with	IN
cord-256444-grw5s2pf	1210	14	the	the	DT
cord-256444-grw5s2pf	1210	15	S	S	NNP
cord-256444-grw5s2pf	1210	16	-	-	HYPH
cord-256444-grw5s2pf	1210	17	M	M	NNP
cord-256444-grw5s2pf	1210	18	complexes	complex	NNS
cord-256444-grw5s2pf	1210	19	which	which	WDT
cord-256444-grw5s2pf	1210	20	halts	halt	VBZ
cord-256444-grw5s2pf	1210	21	the	the	DT
cord-256444-grw5s2pf	1210	22	migration	migration	NN
cord-256444-grw5s2pf	1210	23	of	of	IN
cord-256444-grw5s2pf	1210	24	the	the	DT
cord-256444-grw5s2pf	1210	25	latter	latter	JJ
cord-256444-grw5s2pf	1210	26	and	and	CC
cord-256444-grw5s2pf	1210	27	promotes	promote	VBZ
cord-256444-grw5s2pf	1210	28	budding	bud	VBG
cord-256444-grw5s2pf	1210	29	.	.	.
cord-256444-grw5s2pf	1211	1	Relevant	relevant	JJ
cord-256444-grw5s2pf	1211	2	to	to	IN
cord-256444-grw5s2pf	1211	3	this	this	DT
cord-256444-grw5s2pf	1211	4	notion	notion	NN
cord-256444-grw5s2pf	1211	5	is	be	VBZ
cord-256444-grw5s2pf	1211	6	the	the	DT
cord-256444-grw5s2pf	1211	7	observation	observation	NN
cord-256444-grw5s2pf	1211	8	that	that	IN
cord-256444-grw5s2pf	1211	9	the	the	DT
cord-256444-grw5s2pf	1211	10	nucleocapsids	nucleocapsids	NNPS
cord-256444-grw5s2pf	1211	11	and	and	CC
cord-256444-grw5s2pf	1211	12	free	free	JJ
cord-256444-grw5s2pf	1211	13	N	n	CD
cord-256444-grw5s2pf	1211	14	protein	protein	NN
cord-256444-grw5s2pf	1211	15	have	have	VBP
cord-256444-grw5s2pf	1211	16	affinity	affinity	NN
cord-256444-grw5s2pf	1211	17	for	for	IN
cord-256444-grw5s2pf	1211	18	membranes	membrane	NNS
cord-256444-grw5s2pf	1211	19	(	(	-LRB-
cord-256444-grw5s2pf	1211	20	Anderson	Anderson	NNP
cord-256444-grw5s2pf	1211	21	and	and	CC
cord-256444-grw5s2pf	1211	22	Wong	Wong	NNP
cord-256444-grw5s2pf	1211	23	,	,	,
cord-256444-grw5s2pf	1211	24	1993	1993	CD
cord-256444-grw5s2pf	1211	25	)	)	-RRB-
cord-256444-grw5s2pf	1211	26	.	.	.
cord-256444-grw5s2pf	1212	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1212	2	should	should	MD
cord-256444-grw5s2pf	1212	3	be	be	VB
cord-256444-grw5s2pf	1212	4	remembered	remember	VBN
cord-256444-grw5s2pf	1212	5	,	,	,
cord-256444-grw5s2pf	1212	6	however	however	RB
cord-256444-grw5s2pf	1212	7	,	,	,
cord-256444-grw5s2pf	1212	8	that	that	IN
cord-256444-grw5s2pf	1212	9	in	in	IN
cord-256444-grw5s2pf	1212	10	the	the	DT
cord-256444-grw5s2pf	1212	11	absence	absence	NN
cord-256444-grw5s2pf	1212	12	of	of	IN
cord-256444-grw5s2pf	1212	13	S	S	NNP
cord-256444-grw5s2pf	1212	14	,	,	,
cord-256444-grw5s2pf	1212	15	HE	HE	NNP
cord-256444-grw5s2pf	1212	16	,	,	,
cord-256444-grw5s2pf	1212	17	and	and	CC
cord-256444-grw5s2pf	1212	18	nucleocapsids	nucleocapsid	NNS
cord-256444-grw5s2pf	1212	19	,	,	,
cord-256444-grw5s2pf	1212	20	the	the	DT
cord-256444-grw5s2pf	1212	21	E	E	NNP
cord-256444-grw5s2pf	1212	22	and	and	CC
cord-256444-grw5s2pf	1212	23	M	M	NNP
cord-256444-grw5s2pf	1212	24	proteins	protein	NNS
cord-256444-grw5s2pf	1212	25	alone	alone	RB
cord-256444-grw5s2pf	1212	26	can	can	MD
cord-256444-grw5s2pf	1212	27	induce	induce	VB
cord-256444-grw5s2pf	1212	28	budding	bud	VBG
cord-256444-grw5s2pf	1212	29	to	to	TO
cord-256444-grw5s2pf	1212	30	form	form	VB
cord-256444-grw5s2pf	1212	31	VLPs	vlp	NNS
cord-256444-grw5s2pf	1212	32	(	(	-LRB-
cord-256444-grw5s2pf	1212	33	Bos	Bos	NNP
cord-256444-grw5s2pf	1212	34	et	et	NNP
cord-256444-grw5s2pf	1212	35	al	al	NNP
cord-256444-grw5s2pf	1212	36	.	.	NNP
cord-256444-grw5s2pf	1212	37	,	,	,
cord-256444-grw5s2pf	1212	38	1996	1996	CD
cord-256444-grw5s2pf	1212	39	;	;	:
cord-256444-grw5s2pf	1212	40	Vennema	Vennema	NNP
cord-256444-grw5s2pf	1212	41	et	et	FW
cord-256444-grw5s2pf	1212	42	al	al	NNP
cord-256444-grw5s2pf	1212	43	.	.	NNP
cord-256444-grw5s2pf	1212	44	,	,	,
cord-256444-grw5s2pf	1212	45	1996	1996	CD
cord-256444-grw5s2pf	1212	46	)	)	-RRB-
cord-256444-grw5s2pf	1212	47	.	.	.
cord-256444-grw5s2pf	1213	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1213	2	is	be	VBZ
cord-256444-grw5s2pf	1213	3	not	not	RB
cord-256444-grw5s2pf	1213	4	yet	yet	RB
cord-256444-grw5s2pf	1213	5	clear	clear	JJ
cord-256444-grw5s2pf	1213	6	whether	whether	IN
cord-256444-grw5s2pf	1213	7	the	the	DT
cord-256444-grw5s2pf	1213	8	budding	bud	VBG
cord-256444-grw5s2pf	1213	9	site	site	NN
cord-256444-grw5s2pf	1213	10	of	of	IN
cord-256444-grw5s2pf	1213	11	VLP	VLP	NNP
cord-256444-grw5s2pf	1213	12	containing	contain	VBG
cord-256444-grw5s2pf	1213	13	only	only	RB
cord-256444-grw5s2pf	1213	14	M	M	NNP
cord-256444-grw5s2pf	1213	15	and	and	CC
cord-256444-grw5s2pf	1213	16	E	E	NNP
cord-256444-grw5s2pf	1213	17	is	be	VBZ
cord-256444-grw5s2pf	1213	18	the	the	DT
cord-256444-grw5s2pf	1213	19	same	same	JJ
cord-256444-grw5s2pf	1213	20	as	as	IN
cord-256444-grw5s2pf	1213	21	that	that	DT
cord-256444-grw5s2pf	1213	22	for	for	IN
cord-256444-grw5s2pf	1213	23	the	the	DT
cord-256444-grw5s2pf	1213	24	complete	complete	JJ
cord-256444-grw5s2pf	1213	25	virion	virion	NN
cord-256444-grw5s2pf	1213	26	.	.	.
cord-256444-grw5s2pf	1214	1	Empty	empty	JJ
cord-256444-grw5s2pf	1214	2	virus	virus	NN
cord-256444-grw5s2pf	1214	3	particles	particle	NNS
cord-256444-grw5s2pf	1214	4	have	have	VBP
cord-256444-grw5s2pf	1214	5	previously	previously	RB
cord-256444-grw5s2pf	1214	6	been	be	VBN
cord-256444-grw5s2pf	1214	7	isolated	isolate	VBN
cord-256444-grw5s2pf	1214	8	from	from	IN
cord-256444-grw5s2pf	1214	9	IBV	IBV	NNP
cord-256444-grw5s2pf	1214	10	,	,	,
cord-256444-grw5s2pf	1214	11	which	which	WDT
cord-256444-grw5s2pf	1214	12	were	be	VBD
cord-256444-grw5s2pf	1214	13	grown	grow	VBN
cord-256444-grw5s2pf	1214	14	in	in	IN
cord-256444-grw5s2pf	1214	15	embryonated	embryonate	VBN
cord-256444-grw5s2pf	1214	16	fowl	fowl	NN
cord-256444-grw5s2pf	1214	17	eggs	egg	NNS
cord-256444-grw5s2pf	1214	18	(	(	-LRB-
cord-256444-grw5s2pf	1214	19	Macnaughton	Macnaughton	NNP
cord-256444-grw5s2pf	1214	20	and	and	CC
cord-256444-grw5s2pf	1214	21	Davies	Davies	NNP
cord-256444-grw5s2pf	1214	22	,	,	,
cord-256444-grw5s2pf	1214	23	1980	1980	CD
cord-256444-grw5s2pf	1214	24	)	)	-RRB-
cord-256444-grw5s2pf	1214	25	.	.	.
cord-256444-grw5s2pf	1215	1	This	this	DT
cord-256444-grw5s2pf	1215	2	supports	support	VBZ
cord-256444-grw5s2pf	1215	3	the	the	DT
cord-256444-grw5s2pf	1215	4	view	view	NN
cord-256444-grw5s2pf	1215	5	that	that	IN
cord-256444-grw5s2pf	1215	6	even	even	RB
cord-256444-grw5s2pf	1215	7	during	during	IN
cord-256444-grw5s2pf	1215	8	natural	natural	JJ
cord-256444-grw5s2pf	1215	9	infection	infection	NN
cord-256444-grw5s2pf	1215	10	,	,	,
cord-256444-grw5s2pf	1215	11	virus	virus	NN
cord-256444-grw5s2pf	1215	12	budding	budding	NN
cord-256444-grw5s2pf	1215	13	can	can	MD
cord-256444-grw5s2pf	1215	14	be	be	VB
cord-256444-grw5s2pf	1215	15	induced	induce	VBN
cord-256444-grw5s2pf	1215	16	without	without	IN
cord-256444-grw5s2pf	1215	17	involvement	involvement	NN
cord-256444-grw5s2pf	1215	18	of	of	IN
cord-256444-grw5s2pf	1215	19	the	the	DT
cord-256444-grw5s2pf	1215	20	viral	viral	JJ
cord-256444-grw5s2pf	1215	21	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1215	22	.	.	.
cord-256444-grw5s2pf	1216	1	Parallels	parallel	NNS
cord-256444-grw5s2pf	1216	2	have	have	VBP
cord-256444-grw5s2pf	1216	3	been	be	VBN
cord-256444-grw5s2pf	1216	4	drawn	draw	VBN
cord-256444-grw5s2pf	1216	5	between	between	IN
cord-256444-grw5s2pf	1216	6	the	the	DT
cord-256444-grw5s2pf	1216	7	E	e	NN
cord-256444-grw5s2pf	1216	8	protein	protein	NN
cord-256444-grw5s2pf	1216	9	of	of	IN
cord-256444-grw5s2pf	1216	10	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1216	11	,	,	,
cord-256444-grw5s2pf	1216	12	the	the	DT
cord-256444-grw5s2pf	1216	13	M2	M2	NNP
cord-256444-grw5s2pf	1216	14	protein	protein	NN
cord-256444-grw5s2pf	1216	15	of	of	IN
cord-256444-grw5s2pf	1216	16	orthomyxoviruses	orthomyxovirus	NNS
cord-256444-grw5s2pf	1216	17	,	,	,
cord-256444-grw5s2pf	1216	18	and	and	CC
cord-256444-grw5s2pf	1216	19	the	the	DT
cord-256444-grw5s2pf	1216	20	6	6	CD
cord-256444-grw5s2pf	1216	21	K	K	NNP
cord-256444-grw5s2pf	1216	22	protein	protein	NN
cord-256444-grw5s2pf	1216	23	of	of	IN
cord-256444-grw5s2pf	1216	24	alphaviruses	alphavirus	NNS
cord-256444-grw5s2pf	1216	25	.	.	.
cord-256444-grw5s2pf	1217	1	All	all	DT
cord-256444-grw5s2pf	1217	2	are	be	VBP
cord-256444-grw5s2pf	1217	3	minor	minor	JJ
cord-256444-grw5s2pf	1217	4	envelope	envelope	NN
cord-256444-grw5s2pf	1217	5	proteins	protein	NNS
cord-256444-grw5s2pf	1217	6	that	that	WDT
cord-256444-grw5s2pf	1217	7	play	play	VBP
cord-256444-grw5s2pf	1217	8	a	a	DT
cord-256444-grw5s2pf	1217	9	role	role	NN
cord-256444-grw5s2pf	1217	10	in	in	IN
cord-256444-grw5s2pf	1217	11	virus	virus	NN
cord-256444-grw5s2pf	1217	12	assembly	assembly	NN
cord-256444-grw5s2pf	1217	13	.	.	.
cord-256444-grw5s2pf	1218	1	Once	once	IN
cord-256444-grw5s2pf	1218	2	the	the	DT
cord-256444-grw5s2pf	1218	3	virus	virus	NN
cord-256444-grw5s2pf	1218	4	particles	particle	NNS
cord-256444-grw5s2pf	1218	5	bud	bud	VBP
cord-256444-grw5s2pf	1218	6	into	into	IN
cord-256444-grw5s2pf	1218	7	the	the	DT
cord-256444-grw5s2pf	1218	8	pre	pre	JJ
cord-256444-grw5s2pf	1218	9	-	-	JJ
cord-256444-grw5s2pf	1218	10	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1218	11	compartment	compartment	NN
cord-256444-grw5s2pf	1218	12	,	,	,
cord-256444-grw5s2pf	1218	13	they	-PRON-	PRP
cord-256444-grw5s2pf	1218	14	are	be	VBP
cord-256444-grw5s2pf	1218	15	transported	transport	VBN
cord-256444-grw5s2pf	1218	16	through	through	IN
cord-256444-grw5s2pf	1218	17	the	the	DT
cord-256444-grw5s2pf	1218	18	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1218	19	complex	complex	NN
cord-256444-grw5s2pf	1218	20	.	.	.
cord-256444-grw5s2pf	1219	1	Whether	whether	IN
cord-256444-grw5s2pf	1219	2	the	the	DT
cord-256444-grw5s2pf	1219	3	Golgiassociated	Golgiassociated	NNP
cord-256444-grw5s2pf	1219	4	posttranslational	posttranslational	JJ
cord-256444-grw5s2pf	1219	5	modifications	modification	NNS
cord-256444-grw5s2pf	1219	6	occur	occur	VBP
cord-256444-grw5s2pf	1219	7	before	before	IN
cord-256444-grw5s2pf	1219	8	or	or	CC
cord-256444-grw5s2pf	1219	9	after	after	IN
cord-256444-grw5s2pf	1219	10	incorporation	incorporation	NN
cord-256444-grw5s2pf	1219	11	of	of	IN
cord-256444-grw5s2pf	1219	12	the	the	DT
cord-256444-grw5s2pf	1219	13	proteins	protein	NNS
cord-256444-grw5s2pf	1219	14	into	into	IN
cord-256444-grw5s2pf	1219	15	virus	virus	NN
cord-256444-grw5s2pf	1219	16	particles	particle	NNS
cord-256444-grw5s2pf	1219	17	is	be	VBZ
cord-256444-grw5s2pf	1219	18	not	not	RB
cord-256444-grw5s2pf	1219	19	known	know	VBN
cord-256444-grw5s2pf	1219	20	.	.	.
cord-256444-grw5s2pf	1220	1	Retrograde	retrograde	JJ
cord-256444-grw5s2pf	1220	2	transport	transport	NN
cord-256444-grw5s2pf	1220	3	of	of	IN
cord-256444-grw5s2pf	1220	4	the	the	DT
cord-256444-grw5s2pf	1220	5	proteins	protein	NNS
cord-256444-grw5s2pf	1220	6	may	may	MD
cord-256444-grw5s2pf	1220	7	be	be	VB
cord-256444-grw5s2pf	1220	8	required	require	VBN
cord-256444-grw5s2pf	1220	9	for	for	IN
cord-256444-grw5s2pf	1220	10	some	some	DT
cord-256444-grw5s2pf	1220	11	steps	step	NNS
cord-256444-grw5s2pf	1220	12	of	of	IN
cord-256444-grw5s2pf	1220	13	the	the	DT
cord-256444-grw5s2pf	1220	14	virus	virus	NN
cord-256444-grw5s2pf	1220	15	assembly	assembly	NN
cord-256444-grw5s2pf	1220	16	process	process	NN
cord-256444-grw5s2pf	1220	17	.	.	.
cord-256444-grw5s2pf	1221	1	Finally	finally	RB
cord-256444-grw5s2pf	1221	2	,	,	,
cord-256444-grw5s2pf	1221	3	the	the	DT
cord-256444-grw5s2pf	1221	4	release	release	NN
cord-256444-grw5s2pf	1221	5	of	of	IN
cord-256444-grw5s2pf	1221	6	virus	virus	NN
cord-256444-grw5s2pf	1221	7	particles	particle	NNS
cord-256444-grw5s2pf	1221	8	from	from	IN
cord-256444-grw5s2pf	1221	9	the	the	DT
cord-256444-grw5s2pf	1221	10	cells	cell	NNS
cord-256444-grw5s2pf	1221	11	appears	appear	VBZ
cord-256444-grw5s2pf	1221	12	to	to	TO
cord-256444-grw5s2pf	1221	13	be	be	VB
cord-256444-grw5s2pf	1221	14	restricted	restrict	VBN
cord-256444-grw5s2pf	1221	15	to	to	IN
cord-256444-grw5s2pf	1221	16	certain	certain	JJ
cord-256444-grw5s2pf	1221	17	areas	area	NNS
cord-256444-grw5s2pf	1221	18	of	of	IN
cord-256444-grw5s2pf	1221	19	cells	cell	NNS
cord-256444-grw5s2pf	1221	20	.	.	.
cord-256444-grw5s2pf	1222	1	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1222	2	grown	grow	VBN
cord-256444-grw5s2pf	1222	3	in	in	IN
cord-256444-grw5s2pf	1222	4	polarized	polarized	JJ
cord-256444-grw5s2pf	1222	5	LLC	LLC	NNP
cord-256444-grw5s2pf	1222	6	-	-	HYPH
cord-256444-grw5s2pf	1222	7	PK1	PK1	NNP
cord-256444-grw5s2pf	1222	8	cells	cell	NNS
cord-256444-grw5s2pf	1222	9	both	both	DT
cord-256444-grw5s2pf	1222	10	enter	enter	VBP
cord-256444-grw5s2pf	1222	11	and	and	CC
cord-256444-grw5s2pf	1222	12	exit	exit	NN
cord-256444-grw5s2pf	1222	13	by	by	IN
cord-256444-grw5s2pf	1222	14	the	the	DT
cord-256444-grw5s2pf	1222	15	apical	apical	JJ
cord-256444-grw5s2pf	1222	16	surface	surface	NN
cord-256444-grw5s2pf	1222	17	(	(	-LRB-
cord-256444-grw5s2pf	1222	18	Rossen	Rossen	NNP
cord-256444-grw5s2pf	1222	19	et	et	NNP
cord-256444-grw5s2pf	1222	20	al	al	NNP
cord-256444-grw5s2pf	1222	21	.	.	NNP
cord-256444-grw5s2pf	1222	22	,	,	,
cord-256444-grw5s2pf	1222	23	1994	1994	CD
cord-256444-grw5s2pf	1222	24	)	)	-RRB-
cord-256444-grw5s2pf	1222	25	,	,	,
cord-256444-grw5s2pf	1222	26	whereas	whereas	IN
cord-256444-grw5s2pf	1222	27	MHV	MHV	NNP
cord-256444-grw5s2pf	1222	28	-	-	HYPH
cord-256444-grw5s2pf	1222	29	A59	A59	NNP
cord-256444-grw5s2pf	1222	30	enters	enter	VBZ
cord-256444-grw5s2pf	1222	31	polarized	polarize	VBN
cord-256444-grw5s2pf	1222	32	murine	murine	JJ
cord-256444-grw5s2pf	1222	33	kidney	kidney	NN
cord-256444-grw5s2pf	1222	34	cells	cell	NNS
cord-256444-grw5s2pf	1222	35	(	(	-LRB-
cord-256444-grw5s2pf	1222	36	mTAL	mTAL	NNP
cord-256444-grw5s2pf	1222	37	)	)	-RRB-
cord-256444-grw5s2pf	1222	38	by	by	IN
cord-256444-grw5s2pf	1222	39	the	the	DT
cord-256444-grw5s2pf	1222	40	apical	apical	JJ
cord-256444-grw5s2pf	1222	41	surface	surface	NN
cord-256444-grw5s2pf	1222	42	but	but	CC
cord-256444-grw5s2pf	1222	43	is	be	VBZ
cord-256444-grw5s2pf	1222	44	released	release	VBN
cord-256444-grw5s2pf	1222	45	via	via	IN
cord-256444-grw5s2pf	1222	46	the	the	DT
cord-256444-grw5s2pf	1222	47	basolateral	basolateral	JJ
cord-256444-grw5s2pf	1222	48	surface	surface	NN
cord-256444-grw5s2pf	1222	49	(	(	-LRB-
cord-256444-grw5s2pf	1222	50	Rossen	Rossen	NNP
cord-256444-grw5s2pf	1222	51	et	et	NNP
cord-256444-grw5s2pf	1222	52	al	al	NNP
cord-256444-grw5s2pf	1222	53	.	.	NNP
cord-256444-grw5s2pf	1222	54	,	,	,
cord-256444-grw5s2pf	1222	55	1995a	1995a	CD
cord-256444-grw5s2pf	1222	56	)	)	-RRB-
cord-256444-grw5s2pf	1222	57	.	.	.
cord-256444-grw5s2pf	1223	1	However	however	RB
cord-256444-grw5s2pf	1223	2	,	,	,
cord-256444-grw5s2pf	1223	3	the	the	DT
cord-256444-grw5s2pf	1223	4	site	site	NN
cord-256444-grw5s2pf	1223	5	of	of	IN
cord-256444-grw5s2pf	1223	6	virus	virus	NN
cord-256444-grw5s2pf	1223	7	release	release	NN
cord-256444-grw5s2pf	1223	8	varies	vary	VBZ
cord-256444-grw5s2pf	1223	9	with	with	IN
cord-256444-grw5s2pf	1223	10	different	different	JJ
cord-256444-grw5s2pf	1223	11	cell	cell	NN
cord-256444-grw5s2pf	1223	12	lines	line	NNS
cord-256444-grw5s2pf	1223	13	(	(	-LRB-
cord-256444-grw5s2pf	1223	14	Rossen	Rossen	NNP
cord-256444-grw5s2pf	1223	15	et	et	NNP
cord-256444-grw5s2pf	1223	16	al	al	NNP
cord-256444-grw5s2pf	1223	17	.	.	NNP
cord-256444-grw5s2pf	1223	18	,	,	,
cord-256444-grw5s2pf	1223	19	1997	1997	CD
cord-256444-grw5s2pf	1223	20	)	)	-RRB-
cord-256444-grw5s2pf	1223	21	.	.	.
cord-256444-grw5s2pf	1224	1	The	the	DT
cord-256444-grw5s2pf	1224	2	factors	factor	NNS
cord-256444-grw5s2pf	1224	3	governing	govern	VBG
cord-256444-grw5s2pf	1224	4	this	this	DT
cord-256444-grw5s2pf	1224	5	process	process	NN
cord-256444-grw5s2pf	1224	6	are	be	VBP
cord-256444-grw5s2pf	1224	7	not	not	RB
cord-256444-grw5s2pf	1224	8	known	know	VBN
cord-256444-grw5s2pf	1224	9	(	(	-LRB-
cord-256444-grw5s2pf	1224	10	Rossen	Rossen	NNP
cord-256444-grw5s2pf	1224	11	et	et	NNP
cord-256444-grw5s2pf	1224	12	al	al	NNP
cord-256444-grw5s2pf	1224	13	.	.	NNP
cord-256444-grw5s2pf	1224	14	,	,	,
cord-256444-grw5s2pf	1224	15	1995b	1995b	CD
cord-256444-grw5s2pf	1224	16	)	)	-RRB-
cord-256444-grw5s2pf	1224	17	.	.	.
cord-256444-grw5s2pf	1225	1	Probably	probably	RB
cord-256444-grw5s2pf	1225	2	because	because	IN
cord-256444-grw5s2pf	1225	3	of	of	IN
cord-256444-grw5s2pf	1225	4	the	the	DT
cord-256444-grw5s2pf	1225	5	large	large	JJ
cord-256444-grw5s2pf	1225	6	size	size	NN
cord-256444-grw5s2pf	1225	7	of	of	IN
cord-256444-grw5s2pf	1225	8	their	-PRON-	PRP$
cord-256444-grw5s2pf	1225	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1225	10	genomes	genome	NNS
cord-256444-grw5s2pf	1225	11	,	,	,
cord-256444-grw5s2pf	1225	12	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1225	13	have	have	VBP
cord-256444-grw5s2pf	1225	14	developed	develop	VBN
cord-256444-grw5s2pf	1225	15	a	a	DT
cord-256444-grw5s2pf	1225	16	variety	variety	NN
cord-256444-grw5s2pf	1225	17	of	of	IN
cord-256444-grw5s2pf	1225	18	genetic	genetic	JJ
cord-256444-grw5s2pf	1225	19	mechanisms	mechanism	NNS
cord-256444-grw5s2pf	1225	20	,	,	,
cord-256444-grw5s2pf	1225	21	among	among	IN
cord-256444-grw5s2pf	1225	22	which	which	WDT
cord-256444-grw5s2pf	1225	23	are	be	VBP
cord-256444-grw5s2pf	1225	24	RNA	RNA	NNP
cord-256444-grw5s2pf	1225	25	recombination	recombination	NN
cord-256444-grw5s2pf	1225	26	and	and	CC
cord-256444-grw5s2pf	1225	27	generation	generation	NN
cord-256444-grw5s2pf	1225	28	of	of	IN
cord-256444-grw5s2pf	1225	29	DI	DI	NNP
cord-256444-grw5s2pf	1225	30	RNA	RNA	NNP
cord-256444-grw5s2pf	1225	31	,	,	,
cord-256444-grw5s2pf	1225	32	to	to	TO
cord-256444-grw5s2pf	1225	33	maintain	maintain	VB
cord-256444-grw5s2pf	1225	34	their	-PRON-	PRP$
cord-256444-grw5s2pf	1225	35	genetic	genetic	JJ
cord-256444-grw5s2pf	1225	36	stability	stability	NN
cord-256444-grw5s2pf	1225	37	and	and	CC
cord-256444-grw5s2pf	1225	38	,	,	,
cord-256444-grw5s2pf	1225	39	as	as	IN
cord-256444-grw5s2pf	1225	40	a	a	DT
cord-256444-grw5s2pf	1225	41	side	side	NN
cord-256444-grw5s2pf	1225	42	product	product	NN
cord-256444-grw5s2pf	1225	43	,	,	,
cord-256444-grw5s2pf	1225	44	generate	generate	VB
cord-256444-grw5s2pf	1225	45	diversity	diversity	NN
cord-256444-grw5s2pf	1225	46	.	.	.
cord-256444-grw5s2pf	1226	1	Coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1226	2	also	also	RB
cord-256444-grw5s2pf	1226	3	readily	readily	RB
cord-256444-grw5s2pf	1226	4	undergo	undergo	VBP
cord-256444-grw5s2pf	1226	5	genetic	genetic	JJ
cord-256444-grw5s2pf	1226	6	mutation	mutation	NN
cord-256444-grw5s2pf	1226	7	,	,	,
cord-256444-grw5s2pf	1226	8	a	a	DT
cord-256444-grw5s2pf	1226	9	characteristic	characteristic	JJ
cord-256444-grw5s2pf	1226	10	common	common	JJ
cord-256444-grw5s2pf	1226	11	to	to	IN
cord-256444-grw5s2pf	1226	12	all	all	DT
cord-256444-grw5s2pf	1226	13	RNA	RNA	NNP
cord-256444-grw5s2pf	1226	14	viruses	virus	NNS
cord-256444-grw5s2pf	1226	15	.	.	.
cord-256444-grw5s2pf	1227	1	Thus	thus	RB
cord-256444-grw5s2pf	1227	2	,	,	,
cord-256444-grw5s2pf	1227	3	they	-PRON-	PRP
cord-256444-grw5s2pf	1227	4	evolve	evolve	VBP
cord-256444-grw5s2pf	1227	5	rapidly	rapidly	RB
cord-256444-grw5s2pf	1227	6	and	and	CC
cord-256444-grw5s2pf	1227	7	are	be	VBP
cord-256444-grw5s2pf	1227	8	heterogeneous	heterogeneous	JJ
cord-256444-grw5s2pf	1227	9	.	.	.
cord-256444-grw5s2pf	1228	1	These	these	DT
cord-256444-grw5s2pf	1228	2	genetic	genetic	JJ
cord-256444-grw5s2pf	1228	3	phenomena	phenomenon	NNS
cord-256444-grw5s2pf	1228	4	provide	provide	VBP
cord-256444-grw5s2pf	1228	5	virologists	virologist	NNS
cord-256444-grw5s2pf	1228	6	with	with	IN
cord-256444-grw5s2pf	1228	7	useful	useful	JJ
cord-256444-grw5s2pf	1228	8	tools	tool	NNS
cord-256444-grw5s2pf	1228	9	for	for	IN
cord-256444-grw5s2pf	1228	10	understanding	understand	VBG
cord-256444-grw5s2pf	1228	11	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1228	12	biology	biology	NN
cord-256444-grw5s2pf	1228	13	,	,	,
cord-256444-grw5s2pf	1228	14	particularly	particularly	RB
cord-256444-grw5s2pf	1228	15	because	because	IN
cord-256444-grw5s2pf	1228	16	reverse	reverse	JJ
cord-256444-grw5s2pf	1228	17	genetics	genetics	NN
cord-256444-grw5s2pf	1228	18	studies	study	NNS
cord-256444-grw5s2pf	1228	19	for	for	IN
cord-256444-grw5s2pf	1228	20	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1228	21	are	be	VBP
cord-256444-grw5s2pf	1228	22	not	not	RB
cord-256444-grw5s2pf	1228	23	yet	yet	RB
cord-256444-grw5s2pf	1228	24	feasible	feasible	JJ
cord-256444-grw5s2pf	1228	25	.	.	.
cord-256444-grw5s2pf	1229	1	Using	use	VBG
cord-256444-grw5s2pf	1229	2	a	a	DT
cord-256444-grw5s2pf	1229	3	variety	variety	NN
cord-256444-grw5s2pf	1229	4	of	of	IN
cord-256444-grw5s2pf	1229	5	chemical	chemical	JJ
cord-256444-grw5s2pf	1229	6	mutagens	mutagen	NNS
cord-256444-grw5s2pf	1229	7	,	,	,
cord-256444-grw5s2pf	1229	8	several	several	JJ
cord-256444-grw5s2pf	1229	9	laboratories	laboratory	NNS
cord-256444-grw5s2pf	1229	10	have	have	VBP
cord-256444-grw5s2pf	1229	11	isolated	isolate	VBN
cord-256444-grw5s2pf	1229	12	MHV	MHV	NNP
cord-256444-grw5s2pf	1229	13	temperature	temperature	NN
cord-256444-grw5s2pf	1229	14	-	-	HYPH
cord-256444-grw5s2pf	1229	15	sensitive	sensitive	JJ
cord-256444-grw5s2pf	1229	16	(	(	-LRB-
cord-256444-grw5s2pf	1229	17	ts	ts	NNP
cord-256444-grw5s2pf	1229	18	)	)	-RRB-
cord-256444-grw5s2pf	1229	19	mutants	mutant	NNS
cord-256444-grw5s2pf	1229	20	which	which	WDT
cord-256444-grw5s2pf	1229	21	can	can	MD
cord-256444-grw5s2pf	1229	22	not	not	RB
cord-256444-grw5s2pf	1229	23	produce	produce	VB
cord-256444-grw5s2pf	1229	24	infectious	infectious	JJ
cord-256444-grw5s2pf	1229	25	virus	virus	NN
cord-256444-grw5s2pf	1229	26	particles	particle	NNS
cord-256444-grw5s2pf	1229	27	or	or	CC
cord-256444-grw5s2pf	1229	28	cause	cause	VB
cord-256444-grw5s2pf	1229	29	different	different	JJ
cord-256444-grw5s2pf	1229	30	plaque	plaque	NN
cord-256444-grw5s2pf	1229	31	morphology	morphology	NN
cord-256444-grw5s2pf	1229	32	at	at	IN
cord-256444-grw5s2pf	1229	33	the	the	DT
cord-256444-grw5s2pf	1229	34	nonpermissive	nonpermissive	JJ
cord-256444-grw5s2pf	1229	35	temperature	temperature	NN
cord-256444-grw5s2pf	1230	1	(	(	-LRB-
cord-256444-grw5s2pf	1230	2	Haspel	Haspel	NNP
cord-256444-grw5s2pf	1230	3	et	et	NNP
cord-256444-grw5s2pf	1230	4	al	al	NNP
cord-256444-grw5s2pf	1230	5	.	.	.
cord-256444-grw5s2pf	1231	1	,	,	,
cord-256444-grw5s2pf	1231	2	1978	1978	CD
cord-256444-grw5s2pf	1231	3	;	;	:
cord-256444-grw5s2pf	1231	4	Robb	Robb	NNP
cord-256444-grw5s2pf	1231	5	et	et	FW
cord-256444-grw5s2pf	1231	6	al	al	NNP
cord-256444-grw5s2pf	1231	7	.	.	NNP
cord-256444-grw5s2pf	1231	8	,	,	,
cord-256444-grw5s2pf	1231	9	1979	1979	CD
cord-256444-grw5s2pf	1231	10	;	;	:
cord-256444-grw5s2pf	1231	11	Wege	Wege	NNP
cord-256444-grw5s2pf	1231	12	et	et	NNP
cord-256444-grw5s2pf	1231	13	al	al	NNP
cord-256444-grw5s2pf	1231	14	.	.	.
cord-256444-grw5s2pf	1232	1	,	,	,
cord-256444-grw5s2pf	1232	2	1981	1981	CD
cord-256444-grw5s2pf	1232	3	;	;	:
cord-256444-grw5s2pf	1232	4	Koolen	Koolen	NNP
cord-256444-grw5s2pf	1232	5	et	et	NNP
cord-256444-grw5s2pf	1232	6	al	al	NNP
cord-256444-grw5s2pf	1232	7	.	.	NNP
cord-256444-grw5s2pf	1232	8	,	,	,
cord-256444-grw5s2pf	1232	9	1983	1983	CD
cord-256444-grw5s2pf	1232	10	;	;	:
cord-256444-grw5s2pf	1232	11	Schaad	Schaad	NNP
cord-256444-grw5s2pf	1232	12	et	et	NNP
cord-256444-grw5s2pf	1232	13	al	al	NNP
cord-256444-grw5s2pf	1232	14	.	.	NNP
cord-256444-grw5s2pf	1232	15	,	,	,
cord-256444-grw5s2pf	1232	16	1990	1990	CD
cord-256444-grw5s2pf	1232	17	)	)	-RRB-
cord-256444-grw5s2pf	1232	18	.	.	.
cord-256444-grw5s2pf	1233	1	Some	some	DT
cord-256444-grw5s2pf	1233	2	of	of	IN
cord-256444-grw5s2pf	1233	3	these	these	DT
cord-256444-grw5s2pf	1233	4	mutants	mutant	NNS
cord-256444-grw5s2pf	1233	5	have	have	VBP
cord-256444-grw5s2pf	1233	6	been	be	VBN
cord-256444-grw5s2pf	1233	7	characterized	characterize	VBN
cord-256444-grw5s2pf	1233	8	with	with	IN
cord-256444-grw5s2pf	1233	9	respect	respect	NN
cord-256444-grw5s2pf	1233	10	to	to	IN
cord-256444-grw5s2pf	1233	11	their	-PRON-	PRP$
cord-256444-grw5s2pf	1233	12	ability	ability	NN
cord-256444-grw5s2pf	1233	13	to	to	TO
cord-256444-grw5s2pf	1233	14	synthesize	synthesize	VB
cord-256444-grw5s2pf	1233	15	RNA	RNA	NNP
cord-256444-grw5s2pf	1233	16	and	and	CC
cord-256444-grw5s2pf	1233	17	have	have	VBP
cord-256444-grw5s2pf	1233	18	been	be	VBN
cord-256444-grw5s2pf	1233	19	grouped	group	VBN
cord-256444-grw5s2pf	1233	20	into	into	IN
cord-256444-grw5s2pf	1233	21	at	at	RB
cord-256444-grw5s2pf	1233	22	least	least	RBS
cord-256444-grw5s2pf	1233	23	seven	seven	CD
cord-256444-grw5s2pf	1233	24	complementation	complementation	NN
cord-256444-grw5s2pf	1233	25	groups	group	NNS
cord-256444-grw5s2pf	1233	26	(	(	-LRB-
cord-256444-grw5s2pf	1233	27	Leibowitz	Leibowitz	NNP
cord-256444-grw5s2pf	1233	28	et	et	NNP
cord-256444-grw5s2pf	1233	29	al	al	NNP
cord-256444-grw5s2pf	1233	30	.	.	NNP
cord-256444-grw5s2pf	1233	31	,	,	,
cord-256444-grw5s2pf	1233	32	1982a1	1982a1	CD
cord-256444-grw5s2pf	1233	33	,	,	,
cord-256444-grw5s2pf	1233	34	five	five	CD
cord-256444-grw5s2pf	1233	35	of	of	IN
cord-256444-grw5s2pf	1233	36	which	which	WDT
cord-256444-grw5s2pf	1233	37	have	have	VBP
cord-256444-grw5s2pf	1233	38	the	the	DT
cord-256444-grw5s2pf	1233	39	RNA	RNA	NNP
cord-256444-grw5s2pf	1233	40	(	(	-LRB-
cord-256444-grw5s2pf	1233	41	-1	-1	NN
cord-256444-grw5s2pf	1233	42	phenotype	phenotype	NN
cord-256444-grw5s2pf	1233	43	(	(	-LRB-
cord-256444-grw5s2pf	1233	44	i.e.	i.e.	FW
cord-256444-grw5s2pf	1233	45	,	,	,
cord-256444-grw5s2pf	1233	46	can	can	MD
cord-256444-grw5s2pf	1233	47	not	not	RB
cord-256444-grw5s2pf	1233	48	synthesize	synthesize	VB
cord-256444-grw5s2pf	1233	49	RNA	RNA	NNP
cord-256444-grw5s2pf	1233	50	at	at	IN
cord-256444-grw5s2pf	1233	51	the	the	DT
cord-256444-grw5s2pf	1233	52	nonpermissive	nonpermissive	JJ
cord-256444-grw5s2pf	1233	53	temperature	temperature	NN
cord-256444-grw5s2pf	1233	54	)	)	-RRB-
cord-256444-grw5s2pf	1234	1	(	(	-LRB-
cord-256444-grw5s2pf	1234	2	Leibowitz	Leibowitz	NNP
cord-256444-grw5s2pf	1234	3	et	et	NNP
cord-256444-grw5s2pf	1234	4	al	al	NNP
cord-256444-grw5s2pf	1234	5	.	.	.
cord-256444-grw5s2pf	1235	1	,	,	,
cord-256444-grw5s2pf	1235	2	1982a	1982a	CD
cord-256444-grw5s2pf	1235	3	;	;	:
cord-256444-grw5s2pf	1235	4	Schaad	Schaad	NNP
cord-256444-grw5s2pf	1235	5	et	et	NNP
cord-256444-grw5s2pf	1235	6	al	al	NNP
cord-256444-grw5s2pf	1235	7	.	.	NNP
cord-256444-grw5s2pf	1235	8	,	,	,
cord-256444-grw5s2pf	1235	9	1990	1990	CD
cord-256444-grw5s2pf	1235	10	)	)	-RRB-
cord-256444-grw5s2pf	1236	1	(	(	-LRB-
cord-256444-grw5s2pf	1236	2	see	see	VB
cord-256444-grw5s2pf	1236	3	Fig	Fig	NNP
cord-256444-grw5s2pf	1236	4	.	.	.
cord-256444-grw5s2pf	1236	5	6	6	CD
cord-256444-grw5s2pf	1236	6	)	)	-RRB-
cord-256444-grw5s2pf	1236	7	.	.	.
cord-256444-grw5s2pf	1237	1	With	with	IN
cord-256444-grw5s2pf	1237	2	the	the	DT
cord-256444-grw5s2pf	1237	3	use	use	NN
cord-256444-grw5s2pf	1237	4	of	of	IN
cord-256444-grw5s2pf	1237	5	recombination	recombination	NN
cord-256444-grw5s2pf	1237	6	analysis	analysis	NN
cord-256444-grw5s2pf	1237	7	(	(	-LRB-
cord-256444-grw5s2pf	1237	8	see	see	VB
cord-256444-grw5s2pf	1237	9	below	below	RB
cord-256444-grw5s2pf	1237	10	)	)	-RRB-
cord-256444-grw5s2pf	1237	11	,	,	,
cord-256444-grw5s2pf	1237	12	the	the	DT
cord-256444-grw5s2pf	1237	13	possible	possible	JJ
cord-256444-grw5s2pf	1237	14	genetic	genetic	JJ
cord-256444-grw5s2pf	1237	15	defects	defect	NNS
cord-256444-grw5s2pf	1237	16	of	of	IN
cord-256444-grw5s2pf	1237	17	the	the	DT
cord-256444-grw5s2pf	1237	18	mutants	mutant	NNS
cord-256444-grw5s2pf	1237	19	were	be	VBD
cord-256444-grw5s2pf	1237	20	mapped	map	VBN
cord-256444-grw5s2pf	1237	21	on	on	IN
cord-256444-grw5s2pf	1237	22	the	the	DT
cord-256444-grw5s2pf	1237	23	RNA	RNA	NNP
cord-256444-grw5s2pf	1237	24	genome	genome	NN
cord-256444-grw5s2pf	1237	25	Fu	Fu	NNP
cord-256444-grw5s2pf	1237	26	and	and	CC
cord-256444-grw5s2pf	1237	27	Baric	Baric	NNP
cord-256444-grw5s2pf	1237	28	,	,	,
cord-256444-grw5s2pf	1237	29	1994	1994	CD
cord-256444-grw5s2pf	1237	30	)	)	-RRB-
cord-256444-grw5s2pf	1237	31	.	.	.
cord-256444-grw5s2pf	1238	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1238	2	appears	appear	VBZ
cord-256444-grw5s2pf	1238	3	that	that	IN
cord-256444-grw5s2pf	1238	4	all	all	DT
cord-256444-grw5s2pf	1238	5	of	of	IN
cord-256444-grw5s2pf	1238	6	the	the	DT
cord-256444-grw5s2pf	1238	7	RNA	RNA	NNP
cord-256444-grw5s2pf	1238	8	(	(	-LRB-
cord-256444-grw5s2pf	1238	9	-	-	:
cord-256444-grw5s2pf	1238	10	)	)	-RRB-
cord-256444-grw5s2pf	1238	11	mutants	mutant	NNS
cord-256444-grw5s2pf	1238	12	have	have	VBP
cord-256444-grw5s2pf	1238	13	genetic	genetic	JJ
cord-256444-grw5s2pf	1238	14	defects	defect	NNS
cord-256444-grw5s2pf	1238	15	within	within	IN
cord-256444-grw5s2pf	1238	16	gene	gene	NN
cord-256444-grw5s2pf	1238	17	1	1	CD
cord-256444-grw5s2pf	1238	18	,	,	,
cord-256444-grw5s2pf	1238	19	suggesting	suggest	VBG
cord-256444-grw5s2pf	1238	20	that	that	IN
cord-256444-grw5s2pf	1238	21	gene	gene	NN
cord-256444-grw5s2pf	1238	22	1	1	CD
cord-256444-grw5s2pf	1238	23	encodes	encode	VBZ
cord-256444-grw5s2pf	1238	24	RNA	RNA	NNP
cord-256444-grw5s2pf	1238	25	polymerase	polymerase	NN
cord-256444-grw5s2pf	1238	26	and	and	CC
cord-256444-grw5s2pf	1238	27	other	other	JJ
cord-256444-grw5s2pf	1238	28	proteins	protein	NNS
cord-256444-grw5s2pf	1238	29	involved	involve	VBN
cord-256444-grw5s2pf	1238	30	directly	directly	RB
cord-256444-grw5s2pf	1238	31	or	or	CC
cord-256444-grw5s2pf	1238	32	indirectly	indirectly	RB
cord-256444-grw5s2pf	1238	33	in	in	IN
cord-256444-grw5s2pf	1238	34	viral	viral	JJ
cord-256444-grw5s2pf	1238	35	RNA	RNA	NNP
cord-256444-grw5s2pf	1238	36	synthesis	synthesis	NN
cord-256444-grw5s2pf	1238	37	.	.	.
cord-256444-grw5s2pf	1239	1	The	the	DT
cord-256444-grw5s2pf	1239	2	genetic	genetic	JJ
cord-256444-grw5s2pf	1239	3	defects	defect	NNS
cord-256444-grw5s2pf	1239	4	of	of	IN
cord-256444-grw5s2pf	1239	5	some	some	DT
cord-256444-grw5s2pf	1239	6	of	of	IN
cord-256444-grw5s2pf	1239	7	these	these	DT
cord-256444-grw5s2pf	1239	8	mutants	mutant	NNS
cord-256444-grw5s2pf	1239	9	have	have	VBP
cord-256444-grw5s2pf	1239	10	been	be	VBN
cord-256444-grw5s2pf	1239	11	confirmed	confirm	VBN
cord-256444-grw5s2pf	1239	12	by	by	IN
cord-256444-grw5s2pf	1239	13	RNA	RNA	NNP
cord-256444-grw5s2pf	1239	14	sequence	sequence	NN
cord-256444-grw5s2pf	1239	15	analysis	analysis	NN
cord-256444-grw5s2pf	1239	16	of	of	IN
cord-256444-grw5s2pf	1239	17	the	the	DT
cord-256444-grw5s2pf	1239	18	mutants	mutant	NNS
cord-256444-grw5s2pf	1239	19	and	and	CC
cord-256444-grw5s2pf	1239	20	their	-PRON-	PRP$
cord-256444-grw5s2pf	1239	21	revertants	revertant	NNS
cord-256444-grw5s2pf	1239	22	.	.	.
cord-256444-grw5s2pf	1240	1	These	these	DT
cord-256444-grw5s2pf	1240	2	five	five	CD
cord-256444-grw5s2pf	1240	3	different	different	JJ
cord-256444-grw5s2pf	1240	4	complementation	complementation	NN
cord-256444-grw5s2pf	1240	5	groups	group	NNS
cord-256444-grw5s2pf	1240	6	have	have	VBP
cord-256444-grw5s2pf	1240	7	been	be	VBN
cord-256444-grw5s2pf	1240	8	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	1240	9	to	to	TO
cord-256444-grw5s2pf	1240	10	affect	affect	VB
cord-256444-grw5s2pf	1240	11	different	different	JJ
cord-256444-grw5s2pf	1240	12	steps	step	NNS
cord-256444-grw5s2pf	1240	13	of	of	IN
cord-256444-grw5s2pf	1240	14	RNA	RNA	NNP
cord-256444-grw5s2pf	1240	15	synthesis	synthesis	NN
cord-256444-grw5s2pf	1240	16	,	,	,
cord-256444-grw5s2pf	1240	17	including	include	VBG
cord-256444-grw5s2pf	1240	18	the	the	DT
cord-256444-grw5s2pf	1240	19	synthesis	synthesis	NN
cord-256444-grw5s2pf	1240	20	of	of	IN
cord-256444-grw5s2pf	1240	21	leader	leader	NN
cord-256444-grw5s2pf	1240	22	RNA	RNA	NNP
cord-256444-grw5s2pf	1240	23	,	,	,
cord-256444-grw5s2pf	1240	24	negative	negative	JJ
cord-256444-grw5s2pf	1240	25	-	-	HYPH
cord-256444-grw5s2pf	1240	26	strand	strand	NN
cord-256444-grw5s2pf	1240	27	RNA	RNA	NNP
cord-256444-grw5s2pf	1240	28	,	,	,
cord-256444-grw5s2pf	1240	29	and	and	CC
cord-256444-grw5s2pf	1240	30	positive	positive	JJ
cord-256444-grw5s2pf	1240	31	-	-	HYPH
cord-256444-grw5s2pf	1240	32	strand	strand	NN
cord-256444-grw5s2pf	1240	33	RNA	RNA	NNP
cord-256444-grw5s2pf	1240	34	(	(	-LRB-
cord-256444-grw5s2pf	1240	35	Fig	Fig	NNP
cord-256444-grw5s2pf	1240	36	.	.	.
cord-256444-grw5s2pf	1240	37	6	6	CD
cord-256444-grw5s2pf	1240	38	)	)	-RRB-
cord-256444-grw5s2pf	1240	39	,	,	,
cord-256444-grw5s2pf	1240	40	suggesting	suggest	VBG
cord-256444-grw5s2pf	1240	41	that	that	IN
cord-256444-grw5s2pf	1240	42	different	different	JJ
cord-256444-grw5s2pf	1240	43	steps	step	NNS
cord-256444-grw5s2pf	1240	44	of	of	IN
cord-256444-grw5s2pf	1240	45	RNA	RNA	NNP
cord-256444-grw5s2pf	1240	46	synthesis	synthesis	NN
cord-256444-grw5s2pf	1240	47	require	require	VBP
cord-256444-grw5s2pf	1240	48	different	different	JJ
cord-256444-grw5s2pf	1240	49	viral	viral	JJ
cord-256444-grw5s2pf	1240	50	proteins	protein	NNS
cord-256444-grw5s2pf	1240	51	.	.	.
cord-256444-grw5s2pf	1241	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1241	2	is	be	VBZ
cord-256444-grw5s2pf	1241	3	still	still	RB
cord-256444-grw5s2pf	1241	4	not	not	RB
cord-256444-grw5s2pf	1241	5	possible	possible	JJ
cord-256444-grw5s2pf	1241	6	,	,	,
cord-256444-grw5s2pf	1241	7	however	however	RB
cord-256444-grw5s2pf	1241	8	,	,	,
cord-256444-grw5s2pf	1241	9	to	to	TO
cord-256444-grw5s2pf	1241	10	correlate	correlate	VB
cord-256444-grw5s2pf	1241	11	the	the	DT
cord-256444-grw5s2pf	1241	12	genetic	genetic	JJ
cord-256444-grw5s2pf	1241	13	defects	defect	NNS
cord-256444-grw5s2pf	1241	14	definitively	definitively	RB
cord-256444-grw5s2pf	1241	15	with	with	IN
cord-256444-grw5s2pf	1241	16	the	the	DT
cord-256444-grw5s2pf	1241	17	known	know	VBN
cord-256444-grw5s2pf	1241	18	processed	process	VBN
cord-256444-grw5s2pf	1241	19	products	product	NNS
cord-256444-grw5s2pf	1241	20	of	of	IN
cord-256444-grw5s2pf	1241	21	the	the	DT
cord-256444-grw5s2pf	1241	22	gene	gene	NN
cord-256444-grw5s2pf	1241	23	1	1	CD
cord-256444-grw5s2pf	1241	24	polyprotein	polyprotein	NN
cord-256444-grw5s2pf	1241	25	.	.	.
cord-256444-grw5s2pf	1242	1	Among	among	IN
cord-256444-grw5s2pf	1242	2	the	the	DT
cord-256444-grw5s2pf	1242	3	RNA	RNA	NNP
cord-256444-grw5s2pf	1242	4	(	(	-LRB-
cord-256444-grw5s2pf	1242	5	+	+	NNS
cord-256444-grw5s2pf	1242	6	)	)	-RRB-
cord-256444-grw5s2pf	1242	7	mutants	mutant	NNS
cord-256444-grw5s2pf	1242	8	,	,	,
cord-256444-grw5s2pf	1242	9	two	two	CD
cord-256444-grw5s2pf	1242	10	complementation	complementation	NN
cord-256444-grw5s2pf	1242	11	groups	group	NNS
cord-256444-grw5s2pf	1242	12	have	have	VBP
cord-256444-grw5s2pf	1242	13	been	be	VBN
cord-256444-grw5s2pf	1242	14	assigned	assign	VBN
cord-256444-grw5s2pf	1242	15	to	to	IN
cord-256444-grw5s2pf	1242	16	the	the	DT
cord-256444-grw5s2pf	1242	17	gene	gene	NN
cord-256444-grw5s2pf	1242	18	encoding	encode	VBG
cord-256444-grw5s2pf	1242	19	the	the	DT
cord-256444-grw5s2pf	1242	20	S	S	NNP
cord-256444-grw5s2pf	1242	21	protein	protein	NN
cord-256444-grw5s2pf	1242	22	Fu	Fu	NNP
cord-256444-grw5s2pf	1242	23	and	and	CC
cord-256444-grw5s2pf	1242	24	Baric	Baric	NNP
cord-256444-grw5s2pf	1242	25	,	,	,
cord-256444-grw5s2pf	1242	26	19941	19941	CD
cord-256444-grw5s2pf	1242	27	,	,	,
cord-256444-grw5s2pf	1242	28	but	but	CC
cord-256444-grw5s2pf	1242	29	the	the	DT
cord-256444-grw5s2pf	1242	30	phenotype	phenotype	NN
cord-256444-grw5s2pf	1242	31	of	of	IN
cord-256444-grw5s2pf	1242	32	these	these	DT
cord-256444-grw5s2pf	1242	33	mutants	mutant	NNS
cord-256444-grw5s2pf	1242	34	has	have	VBZ
cord-256444-grw5s2pf	1242	35	not	not	RB
cord-256444-grw5s2pf	1242	36	been	be	VBN
cord-256444-grw5s2pf	1242	37	well	well	RB
cord-256444-grw5s2pf	1242	38	characterized	characterize	VBN
cord-256444-grw5s2pf	1242	39	.	.	.
cord-256444-grw5s2pf	1243	1	Another	another	DT
cord-256444-grw5s2pf	1243	2	RNA	RNA	NNP
cord-256444-grw5s2pf	1243	3	(	(	-LRB-
cord-256444-grw5s2pf	1243	4	+	+	NNS
cord-256444-grw5s2pf	1243	5	)	)	-RRB-
cord-256444-grw5s2pf	1243	6	mutant	mutant	NN
cord-256444-grw5s2pf	1243	7	,	,	,
cord-256444-grw5s2pf	1243	8	Alb	Alb	NNP
cord-256444-grw5s2pf	1243	9	18	18	CD
cord-256444-grw5s2pf	1243	10	,	,	,
cord-256444-grw5s2pf	1243	11	has	have	VBZ
cord-256444-grw5s2pf	1243	12	a	a	DT
cord-256444-grw5s2pf	1243	13	single	single	JJ
cord-256444-grw5s2pf	1243	14	amino	amino	NN
cord-256444-grw5s2pf	1243	15	acid	acid	NN
cord-256444-grw5s2pf	1243	16	substitution	substitution	NN
cord-256444-grw5s2pf	1243	17	in	in	IN
cord-256444-grw5s2pf	1243	18	the	the	DT
cord-256444-grw5s2pf	1243	19	N	n	CD
cord-256444-grw5s2pf	1243	20	-	-	HYPH
cord-256444-grw5s2pf	1243	21	terminal	terminal	NN
cord-256444-grw5s2pf	1243	22	domain	domain	NN
cord-256444-grw5s2pf	1243	23	of	of	IN
cord-256444-grw5s2pf	1243	24	S	S	NNP
cord-256444-grw5s2pf	1243	25	protein	protein	NN
cord-256444-grw5s2pf	1243	26	and	and	CC
cord-256444-grw5s2pf	1243	27	can	can	MD
cord-256444-grw5s2pf	1243	28	not	not	RB
cord-256444-grw5s2pf	1243	29	incorporate	incorporate	VB
cord-256444-grw5s2pf	1243	30	S	S	NNP
cord-256444-grw5s2pf	1243	31	protein	protein	NN
cord-256444-grw5s2pf	1243	32	into	into	IN
cord-256444-grw5s2pf	1243	33	the	the	DT
cord-256444-grw5s2pf	1243	34	virus	virus	NN
cord-256444-grw5s2pf	1243	35	particles	particle	NNS
cord-256444-grw5s2pf	1243	36	(	(	-LRB-
cord-256444-grw5s2pf	1243	37	Ricard	Ricard	NNP
cord-256444-grw5s2pf	1243	38	et	et	NNP
cord-256444-grw5s2pf	1243	39	al	al	NNP
cord-256444-grw5s2pf	1243	40	.	.	NNP
cord-256444-grw5s2pf	1243	41	,	,	,
cord-256444-grw5s2pf	1243	42	1995	1995	CD
cord-256444-grw5s2pf	1243	43	)	)	-RRB-
cord-256444-grw5s2pf	1243	44	.	.	.
cord-256444-grw5s2pf	1244	1	Still	still	RB
cord-256444-grw5s2pf	1244	2	another	another	DT
cord-256444-grw5s2pf	1244	3	group	group	NN
cord-256444-grw5s2pf	1244	4	of	of	IN
cord-256444-grw5s2pf	1244	5	RNA	RNA	NNP
cord-256444-grw5s2pf	1244	6	(	(	-LRB-
cord-256444-grw5s2pf	1244	7	+	+	NNS
cord-256444-grw5s2pf	1244	8	)	)	-RRB-
cord-256444-grw5s2pf	1244	9	mutants	mutant	NNS
cord-256444-grw5s2pf	1244	10	have	have	VBP
cord-256444-grw5s2pf	1244	11	a	a	DT
cord-256444-grw5s2pf	1244	12	defective	defective	JJ
cord-256444-grw5s2pf	1244	13	N	n	CD
cord-256444-grw5s2pf	1244	14	protein	protein	NN
cord-256444-grw5s2pf	1244	15	(	(	-LRB-
cord-256444-grw5s2pf	1244	16	Koetzner	Koetzner	NNP
cord-256444-grw5s2pf	1244	17	et	et	NNP
cord-256444-grw5s2pf	1244	18	al	al	NNP
cord-256444-grw5s2pf	1244	19	.	.	NNP
cord-256444-grw5s2pf	1244	20	,	,	,
cord-256444-grw5s2pf	1244	21	1992	1992	CD
cord-256444-grw5s2pf	1244	22	;	;	:
cord-256444-grw5s2pf	1244	23	Masters	Masters	NNPS
cord-256444-grw5s2pf	1244	24	et	et	NNP
cord-256444-grw5s2pf	1244	25	al	al	NNP
cord-256444-grw5s2pf	1244	26	.	.	NNP
cord-256444-grw5s2pf	1244	27	,	,	,
cord-256444-grw5s2pf	1244	28	1994	1994	CD
cord-256444-grw5s2pf	1244	29	;	;	:
cord-256444-grw5s2pf	1244	30	Peng	Peng	NNP
cord-256444-grw5s2pf	1244	31	et	et	NNP
cord-256444-grw5s2pf	1244	32	al	al	NNP
cord-256444-grw5s2pf	1244	33	.	.	NNP
cord-256444-grw5s2pf	1244	34	,	,	,
cord-256444-grw5s2pf	1244	35	1995a	1995a	CD
cord-256444-grw5s2pf	1244	36	)	)	-RRB-
cord-256444-grw5s2pf	1244	37	and	and	CC
cord-256444-grw5s2pf	1244	38	produce	produce	VB
cord-256444-grw5s2pf	1244	39	smaller	small	JJR
cord-256444-grw5s2pf	1244	40	plaques	plaque	NNS
cord-256444-grw5s2pf	1244	41	at	at	IN
cord-256444-grw5s2pf	1244	42	the	the	DT
cord-256444-grw5s2pf	1244	43	nonpermissive	nonpermissive	JJ
cord-256444-grw5s2pf	1244	44	temperature	temperature	NN
cord-256444-grw5s2pf	1244	45	;	;	:
cord-256444-grw5s2pf	1244	46	several	several	JJ
cord-256444-grw5s2pf	1244	47	of	of	IN
cord-256444-grw5s2pf	1244	48	these	these	DT
cord-256444-grw5s2pf	1244	49	mutants	mutant	NNS
cord-256444-grw5s2pf	1244	50	have	have	VBP
cord-256444-grw5s2pf	1244	51	a	a	DT
cord-256444-grw5s2pf	1244	52	deletion	deletion	NN
cord-256444-grw5s2pf	1244	53	in	in	IN
cord-256444-grw5s2pf	1244	54	the	the	DT
cord-256444-grw5s2pf	1244	55	N	n	CD
cord-256444-grw5s2pf	1244	56	gene	gene	NN
cord-256444-grw5s2pf	1244	57	(	(	-LRB-
cord-256444-grw5s2pf	1244	58	Masters	Masters	NNP
cord-256444-grw5s2pf	1244	59	,	,	,
cord-256444-grw5s2pf	1244	60	1992	1992	CD
cord-256444-grw5s2pf	1244	61	)	)	-RRB-
cord-256444-grw5s2pf	1244	62	and	and	CC
cord-256444-grw5s2pf	1244	63	are	be	VBP
cord-256444-grw5s2pf	1244	64	defective	defective	JJ
cord-256444-grw5s2pf	1244	65	in	in	IN
cord-256444-grw5s2pf	1244	66	RNA	rna	NN
cord-256444-grw5s2pf	1244	67	-	-	HYPH
cord-256444-grw5s2pf	1244	68	binding	bind	VBG
cord-256444-grw5s2pf	1244	69	activity	activity	NN
cord-256444-grw5s2pf	1245	1	(	(	-LRB-
cord-256444-grw5s2pf	1245	2	Peng	Peng	NNP
cord-256444-grw5s2pf	1245	3	et	et	NNP
cord-256444-grw5s2pf	1245	4	al	al	NNP
cord-256444-grw5s2pf	1245	5	.	.	NNP
cord-256444-grw5s2pf	1245	6	,	,	,
cord-256444-grw5s2pf	1245	7	1995a	1995a	CD
cord-256444-grw5s2pf	1245	8	)	)	-RRB-
cord-256444-grw5s2pf	1245	9	.	.	.
cord-256444-grw5s2pf	1246	1	Most	Most	JJS
cord-256444-grw5s2pf	1246	2	wildtype	wildtype	JJ
cord-256444-grw5s2pf	1246	3	revertants	revertant	NNS
cord-256444-grw5s2pf	1246	4	have	have	VBP
cord-256444-grw5s2pf	1246	5	a	a	DT
cord-256444-grw5s2pf	1246	6	second	second	JJ
cord-256444-grw5s2pf	1246	7	-	-	HYPH
cord-256444-grw5s2pf	1246	8	site	site	NN
cord-256444-grw5s2pf	1246	9	mutation	mutation	NN
cord-256444-grw5s2pf	1246	10	in	in	IN
cord-256444-grw5s2pf	1246	11	the	the	DT
cord-256444-grw5s2pf	1246	12	N	N	NNP
cord-256444-grw5s2pf	1246	13	protein	protein	NN
cord-256444-grw5s2pf	1246	14	and	and	CC
cord-256444-grw5s2pf	1246	15	restored	restore	VBD
cord-256444-grw5s2pf	1246	16	RNA	RNA	NNP
cord-256444-grw5s2pf	1246	17	-	-	HYPH
cord-256444-grw5s2pf	1246	18	binding	bind	VBG
cord-256444-grw5s2pf	1246	19	activity	activity	NN
cord-256444-grw5s2pf	1247	1	(	(	-LRB-
cord-256444-grw5s2pf	1247	2	Peng	Peng	NNP
cord-256444-grw5s2pf	1247	3	et	et	NNP
cord-256444-grw5s2pf	1247	4	al	al	NNP
cord-256444-grw5s2pf	1247	5	.	.	NNP
cord-256444-grw5s2pf	1247	6	,	,	,
cord-256444-grw5s2pf	1247	7	1995a	1995a	CD
cord-256444-grw5s2pf	1247	8	)	)	-RRB-
cord-256444-grw5s2pf	1247	9	.	.	.
cord-256444-grw5s2pf	1248	1	Another	another	DT
cord-256444-grw5s2pf	1248	2	class	class	NN
cord-256444-grw5s2pf	1248	3	of	of	IN
cord-256444-grw5s2pf	1248	4	viral	viral	JJ
cord-256444-grw5s2pf	1248	5	mutants	mutant	NNS
cord-256444-grw5s2pf	1248	6	was	be	VBD
cord-256444-grw5s2pf	1248	7	obtained	obtain	VBN
cord-256444-grw5s2pf	1248	8	by	by	IN
cord-256444-grw5s2pf	1248	9	a	a	DT
cord-256444-grw5s2pf	1248	10	specific	specific	JJ
cord-256444-grw5s2pf	1248	11	selection	selection	NN
cord-256444-grw5s2pf	1248	12	scheme	scheme	NN
cord-256444-grw5s2pf	1248	13	,	,	,
cord-256444-grw5s2pf	1248	14	e.g.	e.g.	RB
cord-256444-grw5s2pf	1248	15	,	,	,
cord-256444-grw5s2pf	1248	16	by	by	IN
cord-256444-grw5s2pf	1248	17	treating	treat	VBG
cord-256444-grw5s2pf	1248	18	viruses	virus	NNS
cord-256444-grw5s2pf	1248	19	with	with	IN
cord-256444-grw5s2pf	1248	20	neutralizing	neutralize	VBG
cord-256444-grw5s2pf	1248	21	MAb	MAb	NNS
cord-256444-grw5s2pf	1248	22	and	and	CC
cord-256444-grw5s2pf	1248	23	selecting	select	VBG
cord-256444-grw5s2pf	1248	24	mutant	mutant	JJ
cord-256444-grw5s2pf	1248	25	viruses	virus	NNS
cord-256444-grw5s2pf	1248	26	resistant	resistant	JJ
cord-256444-grw5s2pf	1248	27	to	to	IN
cord-256444-grw5s2pf	1248	28	neutralization	neutralization	NN
cord-256444-grw5s2pf	1248	29	.	.	.
cord-256444-grw5s2pf	1249	1	Since	since	IN
cord-256444-grw5s2pf	1249	2	neutralizing	neutralize	VBG
cord-256444-grw5s2pf	1249	3	antibodies	antibody	NNS
cord-256444-grw5s2pf	1249	4	are	be	VBP
cord-256444-grw5s2pf	1249	5	usually	usually	RB
cord-256444-grw5s2pf	1249	6	directed	direct	VBN
cord-256444-grw5s2pf	1249	7	against	against	IN
cord-256444-grw5s2pf	1249	8	the	the	DT
cord-256444-grw5s2pf	1249	9	S	S	NNP
cord-256444-grw5s2pf	1249	10	protein	protein	NN
cord-256444-grw5s2pf	1249	11	,	,	,
cord-256444-grw5s2pf	1249	12	all	all	DT
cord-256444-grw5s2pf	1249	13	of	of	IN
cord-256444-grw5s2pf	1249	14	the	the	DT
cord-256444-grw5s2pf	1249	15	neutralizationescape	neutralizationescape	NNP
cord-256444-grw5s2pf	1249	16	mutants	mutant	NNS
cord-256444-grw5s2pf	1249	17	were	be	VBD
cord-256444-grw5s2pf	1249	18	presumed	presume	VBN
cord-256444-grw5s2pf	1249	19	to	to	TO
cord-256444-grw5s2pf	1249	20	have	have	VB
cord-256444-grw5s2pf	1249	21	defects	defect	NNS
cord-256444-grw5s2pf	1249	22	in	in	IN
cord-256444-grw5s2pf	1249	23	the	the	DT
cord-256444-grw5s2pf	1249	24	S	S	NNP
cord-256444-grw5s2pf	1249	25	gene	gene	NN
cord-256444-grw5s2pf	1249	26	.	.	.
cord-256444-grw5s2pf	1250	1	This	this	DT
cord-256444-grw5s2pf	1250	2	was	be	VBD
cord-256444-grw5s2pf	1250	3	indeed	indeed	RB
cord-256444-grw5s2pf	1250	4	the	the	DT
cord-256444-grw5s2pf	1250	5	case	case	NN
cord-256444-grw5s2pf	1250	6	(	(	-LRB-
cord-256444-grw5s2pf	1250	7	reviewed	review	VBN
cord-256444-grw5s2pf	1250	8	by	by	IN
cord-256444-grw5s2pf	1250	9	.	.	.
cord-256444-grw5s2pf	1251	1	Depending	depend	VBG
cord-256444-grw5s2pf	1251	2	on	on	IN
cord-256444-grw5s2pf	1251	3	the	the	DT
cord-256444-grw5s2pf	1251	4	neutralizing	neutralize	VBG
cord-256444-grw5s2pf	1251	5	MAb	MAb	NNS
cord-256444-grw5s2pf	1251	6	used	use	VBN
cord-256444-grw5s2pf	1251	7	for	for	IN
cord-256444-grw5s2pf	1251	8	selection	selection	NN
cord-256444-grw5s2pf	1251	9	,	,	,
cord-256444-grw5s2pf	1251	10	the	the	DT
cord-256444-grw5s2pf	1251	11	mutants	mutant	NNS
cord-256444-grw5s2pf	1251	12	obtained	obtain	VBD
cord-256444-grw5s2pf	1251	13	had	have	VBD
cord-256444-grw5s2pf	1251	14	either	either	CC
cord-256444-grw5s2pf	1251	15	deletions	deletion	NNS
cord-256444-grw5s2pf	1251	16	or	or	CC
cord-256444-grw5s2pf	1251	17	point	point	NN
cord-256444-grw5s2pf	1251	18	mutations	mutation	NNS
cord-256444-grw5s2pf	1251	19	in	in	IN
cord-256444-grw5s2pf	1251	20	the	the	DT
cord-256444-grw5s2pf	1251	21	neutralization	neutralization	NN
cord-256444-grw5s2pf	1251	22	epitopes	epitope	NNS
cord-256444-grw5s2pf	1251	23	of	of	IN
cord-256444-grw5s2pf	1251	24	the	the	DT
cord-256444-grw5s2pf	1251	25	S	S	NNP
cord-256444-grw5s2pf	1251	26	protein	protein	NN
cord-256444-grw5s2pf	1251	27	(	(	-LRB-
cord-256444-grw5s2pf	1251	28	Gallagher	Gallagher	NNP
cord-256444-grw5s2pf	1251	29	et	et	NNP
cord-256444-grw5s2pf	1251	30	al	al	NNP
cord-256444-grw5s2pf	1251	31	.	.	NNP
cord-256444-grw5s2pf	1251	32	,	,	,
cord-256444-grw5s2pf	1251	33	1990	1990	CD
cord-256444-grw5s2pf	1251	34	;	;	:
cord-256444-grw5s2pf	1251	35	Wang	Wang	NNP
cord-256444-grw5s2pf	1251	36	et	et	NNP
cord-256444-grw5s2pf	1251	37	al	al	NNP
cord-256444-grw5s2pf	1251	38	.	.	NNP
cord-256444-grw5s2pf	1251	39	,	,	,
cord-256444-grw5s2pf	1251	40	1992	1992	CD
cord-256444-grw5s2pf	1251	41	)	)	-RRB-
cord-256444-grw5s2pf	1251	42	.	.	.
cord-256444-grw5s2pf	1252	1	These	these	DT
cord-256444-grw5s2pf	1252	2	mutants	mutant	NNS
cord-256444-grw5s2pf	1252	3	generally	generally	RB
cord-256444-grw5s2pf	1252	4	retain	retain	VBP
cord-256444-grw5s2pf	1252	5	growth	growth	NN
cord-256444-grw5s2pf	1252	6	properties	property	NNS
cord-256444-grw5s2pf	1252	7	very	very	RB
cord-256444-grw5s2pf	1252	8	similar	similar	JJ
cord-256444-grw5s2pf	1252	9	to	to	IN
cord-256444-grw5s2pf	1252	10	those	those	DT
cord-256444-grw5s2pf	1252	11	of	of	IN
cord-256444-grw5s2pf	1252	12	the	the	DT
cord-256444-grw5s2pf	1252	13	parental	parental	JJ
cord-256444-grw5s2pf	1252	14	virus	virus	NN
cord-256444-grw5s2pf	1252	15	but	but	CC
cord-256444-grw5s2pf	1252	16	often	often	RB
cord-256444-grw5s2pf	1252	17	have	have	VBP
cord-256444-grw5s2pf	1252	18	significantly	significantly	RB
cord-256444-grw5s2pf	1252	19	different	different	JJ
cord-256444-grw5s2pf	1252	20	pathogenic	pathogenic	JJ
cord-256444-grw5s2pf	1252	21	properties	property	NNS
cord-256444-grw5s2pf	1252	22	with	with	IN
cord-256444-grw5s2pf	1252	23	altered	alter	VBN
cord-256444-grw5s2pf	1252	24	tissue	tissue	NN
cord-256444-grw5s2pf	1252	25	tropism	tropism	NN
cord-256444-grw5s2pf	1252	26	(	(	-LRB-
cord-256444-grw5s2pf	1253	1	Dalziel	Dalziel	NNP
cord-256444-grw5s2pf	1253	2	et	et	NNP
cord-256444-grw5s2pf	1253	3	al	al	NNP
cord-256444-grw5s2pf	1253	4	.	.	.
cord-256444-grw5s2pf	1254	1	,	,	,
cord-256444-grw5s2pf	1254	2	1986	1986	CD
cord-256444-grw5s2pf	1254	3	;	;	:
cord-256444-grw5s2pf	1254	4	Fleming	Fleming	NNP
cord-256444-grw5s2pf	1254	5	et	et	NNP
cord-256444-grw5s2pf	1254	6	al	al	NNP
cord-256444-grw5s2pf	1254	7	.	.	NNP
cord-256444-grw5s2pf	1254	8	,	,	,
cord-256444-grw5s2pf	1254	9	1986	1986	CD
cord-256444-grw5s2pf	1254	10	Fleming	Fleming	NNP
cord-256444-grw5s2pf	1254	11	et	et	NNP
cord-256444-grw5s2pf	1254	12	al	al	NNP
cord-256444-grw5s2pf	1254	13	.	.	NNP
cord-256444-grw5s2pf	1254	14	,	,	,
cord-256444-grw5s2pf	1254	15	,	,	,
cord-256444-grw5s2pf	1254	16	1987	1987	CD
cord-256444-grw5s2pf	1254	17	Wege	Wege	NNP
cord-256444-grw5s2pf	1254	18	et	et	NNP
cord-256444-grw5s2pf	1254	19	al	al	NNP
cord-256444-grw5s2pf	1254	20	.	.	NNP
cord-256444-grw5s2pf	1254	21	,	,	,
cord-256444-grw5s2pf	1254	22	1988	1988	CD
cord-256444-grw5s2pf	1254	23	)	)	-RRB-
cord-256444-grw5s2pf	1254	24	.	.	.
cord-256444-grw5s2pf	1255	1	During	during	IN
cord-256444-grw5s2pf	1255	2	serial	serial	JJ
cord-256444-grw5s2pf	1255	3	virus	virus	NN
cord-256444-grw5s2pf	1255	4	passages	passage	NNS
cord-256444-grw5s2pf	1255	5	in	in	IN
cord-256444-grw5s2pf	1255	6	tissue	tissue	NN
cord-256444-grw5s2pf	1255	7	culture	culture	NN
cord-256444-grw5s2pf	1255	8	or	or	CC
cord-256444-grw5s2pf	1255	9	in	in	IN
cord-256444-grw5s2pf	1255	10	animals	animal	NNS
cord-256444-grw5s2pf	1255	11	,	,	,
cord-256444-grw5s2pf	1255	12	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1255	13	often	often	RB
cord-256444-grw5s2pf	1255	14	undergo	undergo	VBP
cord-256444-grw5s2pf	1255	15	various	various	JJ
cord-256444-grw5s2pf	1255	16	deletions	deletion	NNS
cord-256444-grw5s2pf	1255	17	or	or	CC
cord-256444-grw5s2pf	1255	18	substitutions	substitution	NNS
cord-256444-grw5s2pf	1255	19	even	even	RB
cord-256444-grw5s2pf	1255	20	in	in	IN
cord-256444-grw5s2pf	1255	21	the	the	DT
cord-256444-grw5s2pf	1255	22	absence	absence	NN
cord-256444-grw5s2pf	1255	23	of	of	IN
cord-256444-grw5s2pf	1255	24	experimentally	experimentally	RB
cord-256444-grw5s2pf	1255	25	applied	apply	VBN
cord-256444-grw5s2pf	1255	26	selection	selection	NN
cord-256444-grw5s2pf	1255	27	pressure	pressure	NN
cord-256444-grw5s2pf	1255	28	.	.	.
cord-256444-grw5s2pf	1256	1	These	these	DT
cord-256444-grw5s2pf	1256	2	genetic	genetic	JJ
cord-256444-grw5s2pf	1256	3	changes	change	NNS
cord-256444-grw5s2pf	1256	4	probably	probably	RB
cord-256444-grw5s2pf	1256	5	provide	provide	VBP
cord-256444-grw5s2pf	1256	6	the	the	DT
cord-256444-grw5s2pf	1256	7	emerging	emerge	VBG
cord-256444-grw5s2pf	1256	8	virus	virus	NN
cord-256444-grw5s2pf	1256	9	variants	variant	NNS
cord-256444-grw5s2pf	1256	10	with	with	IN
cord-256444-grw5s2pf	1256	11	evolutionary	evolutionary	JJ
cord-256444-grw5s2pf	1256	12	advantages	advantage	NNS
cord-256444-grw5s2pf	1256	13	under	under	IN
cord-256444-grw5s2pf	1256	14	experimental	experimental	JJ
cord-256444-grw5s2pf	1256	15	conditions	condition	NNS
cord-256444-grw5s2pf	1256	16	or	or	CC
cord-256444-grw5s2pf	1256	17	in	in	IN
cord-256444-grw5s2pf	1256	18	natural	natural	JJ
cord-256444-grw5s2pf	1256	19	infection	infection	NN
cord-256444-grw5s2pf	1256	20	.	.	.
cord-256444-grw5s2pf	1257	1	The	the	DT
cord-256444-grw5s2pf	1257	2	deletions	deletion	NNS
cord-256444-grw5s2pf	1257	3	occur	occur	VBP
cord-256444-grw5s2pf	1257	4	most	most	RBS
cord-256444-grw5s2pf	1257	5	frequently	frequently	RB
cord-256444-grw5s2pf	1257	6	within	within	IN
cord-256444-grw5s2pf	1257	7	the	the	DT
cord-256444-grw5s2pf	1257	8	S	S	NNP
cord-256444-grw5s2pf	1257	9	gene	gene	NN
cord-256444-grw5s2pf	1257	10	,	,	,
cord-256444-grw5s2pf	1257	11	particularly	particularly	RB
cord-256444-grw5s2pf	1257	12	within	within	IN
cord-256444-grw5s2pf	1257	13	a	a	DT
cord-256444-grw5s2pf	1257	14	hypervariable	hypervariable	JJ
cord-256444-grw5s2pf	1257	15	region	region	NN
cord-256444-grw5s2pf	1257	16	encoding	encode	VBG
cord-256444-grw5s2pf	1257	17	the	the	DT
cord-256444-grw5s2pf	1257	18	S1	s1	NN
cord-256444-grw5s2pf	1257	19	subunit	subunit	NN
cord-256444-grw5s2pf	1257	20	(	(	-LRB-
cord-256444-grw5s2pf	1257	21	S.	S.	NNP
cord-256444-grw5s2pf	1257	22	E.	E.	NNP
cord-256444-grw5s2pf	1257	23	Wang	Wang	NNP
cord-256444-grw5s2pf	1257	24	et	et	NNP
cord-256444-grw5s2pf	1257	25	al	al	NNP
cord-256444-grw5s2pf	1257	26	.	.	NNP
cord-256444-grw5s2pf	1257	27	,	,	,
cord-256444-grw5s2pf	1257	28	1992	1992	CD
cord-256444-grw5s2pf	1257	29	)	)	-RRB-
cord-256444-grw5s2pf	1257	30	.	.	.
cord-256444-grw5s2pf	1258	1	In	in	IN
cord-256444-grw5s2pf	1258	2	fact	fact	NN
cord-256444-grw5s2pf	1258	3	,	,	,
cord-256444-grw5s2pf	1258	4	some	some	DT
cord-256444-grw5s2pf	1258	5	natural	natural	JJ
cord-256444-grw5s2pf	1258	6	isolates	isolate	NNS
cord-256444-grw5s2pf	1258	7	of	of	IN
cord-256444-grw5s2pf	1258	8	MHV	MHV	NNP
cord-256444-grw5s2pf	1258	9	have	have	VBP
cord-256444-grw5s2pf	1258	10	a	a	DT
cord-256444-grw5s2pf	1258	11	deletion	deletion	NN
cord-256444-grw5s2pf	1258	12	of	of	IN
cord-256444-grw5s2pf	1258	13	150	150	CD
cord-256444-grw5s2pf	1258	14	-	-	SYM
cord-256444-grw5s2pf	1258	15	460	460	CD
cord-256444-grw5s2pf	1258	16	nucleotides	nucleotide	NNS
cord-256444-grw5s2pf	1258	17	in	in	IN
cord-256444-grw5s2pf	1258	18	this	this	DT
cord-256444-grw5s2pf	1258	19	region	region	NN
cord-256444-grw5s2pf	1258	20	(	(	-LRB-
cord-256444-grw5s2pf	1258	21	Fig	Fig	NNP
cord-256444-grw5s2pf	1258	22	.	.	NNP
cord-256444-grw5s2pf	1258	23	4	4	CD
cord-256444-grw5s2pf	1258	24	)	)	-RRB-
cord-256444-grw5s2pf	1258	25	.	.	.
cord-256444-grw5s2pf	1259	1	Similar	similar	JJ
cord-256444-grw5s2pf	1259	2	deletions	deletion	NNS
cord-256444-grw5s2pf	1259	3	have	have	VBP
cord-256444-grw5s2pf	1259	4	been	be	VBN
cord-256444-grw5s2pf	1259	5	detected	detect	VBN
cord-256444-grw5s2pf	1259	6	in	in	IN
cord-256444-grw5s2pf	1259	7	virus	virus	NN
cord-256444-grw5s2pf	1259	8	variants	variant	NNS
cord-256444-grw5s2pf	1259	9	during	during	IN
cord-256444-grw5s2pf	1259	10	central	central	JJ
cord-256444-grw5s2pf	1259	11	nervous	nervous	JJ
cord-256444-grw5s2pf	1259	12	system	system	NN
cord-256444-grw5s2pf	1259	13	(	(	-LRB-
cord-256444-grw5s2pf	1259	14	CNS	CNS	NNP
cord-256444-grw5s2pf	1259	15	)	)	-RRB-
cord-256444-grw5s2pf	1259	16	infections	infection	NNS
cord-256444-grw5s2pf	1259	17	of	of	IN
cord-256444-grw5s2pf	1259	18	rats	rat	NNS
cord-256444-grw5s2pf	1259	19	.	.	.
cord-256444-grw5s2pf	1260	1	In	in	IN
cord-256444-grw5s2pf	1260	2	persistent	persistent	JJ
cord-256444-grw5s2pf	1260	3	infections	infection	NNS
cord-256444-grw5s2pf	1260	4	of	of	IN
cord-256444-grw5s2pf	1260	5	cultured	cultured	JJ
cord-256444-grw5s2pf	1260	6	cells	cell	NNS
cord-256444-grw5s2pf	1260	7	of	of	IN
cord-256444-grw5s2pf	1260	8	CNS	CNS	NNP
cord-256444-grw5s2pf	1260	9	origin	origin	NN
cord-256444-grw5s2pf	1260	10	,	,	,
cord-256444-grw5s2pf	1260	11	viruses	virus	NNS
cord-256444-grw5s2pf	1260	12	with	with	IN
cord-256444-grw5s2pf	1260	13	point	point	NN
cord-256444-grw5s2pf	1260	14	mutations	mutation	NNS
cord-256444-grw5s2pf	1260	15	or	or	CC
cord-256444-grw5s2pf	1260	16	deletions	deletion	NNS
cord-256444-grw5s2pf	1260	17	in	in	IN
cord-256444-grw5s2pf	1260	18	the	the	DT
cord-256444-grw5s2pf	1260	19	gene	gene	NN
cord-256444-grw5s2pf	1260	20	encoding	encode	VBG
cord-256444-grw5s2pf	1260	21	S	s	NN
cord-256444-grw5s2pf	1260	22	protein	protein	NN
cord-256444-grw5s2pf	1260	23	are	be	VBP
cord-256444-grw5s2pf	1260	24	frequently	frequently	RB
cord-256444-grw5s2pf	1260	25	selected	select	VBN
cord-256444-grw5s2pf	1261	1	(	(	-LRB-
cord-256444-grw5s2pf	1261	2	Gallagher	Gallagher	NNP
cord-256444-grw5s2pf	1261	3	et	et	NNP
cord-256444-grw5s2pf	1261	4	al	al	NNP
cord-256444-grw5s2pf	1261	5	.	.	NNP
cord-256444-grw5s2pf	1261	6	,	,	,
cord-256444-grw5s2pf	1261	7	1991	1991	CD
cord-256444-grw5s2pf	1261	8	;	;	:
cord-256444-grw5s2pf	1262	1	Gombold	Gombold	NNP
cord-256444-grw5s2pf	1262	2	et	et	NNP
cord-256444-grw5s2pf	1262	3	al	al	NNP
cord-256444-grw5s2pf	1262	4	.	.	.
cord-256444-grw5s2pf	1263	1	,	,	,
cord-256444-grw5s2pf	1263	2	1993	1993	CD
cord-256444-grw5s2pf	1263	3	;	;	:
cord-256444-grw5s2pf	1263	4	Rowe	Rowe	NNP
cord-256444-grw5s2pf	1263	5	et	et	NNP
cord-256444-grw5s2pf	1263	6	al	al	NNP
cord-256444-grw5s2pf	1263	7	.	.	NNP
cord-256444-grw5s2pf	1263	8	,	,	,
cord-256444-grw5s2pf	1263	9	1997	1997	CD
cord-256444-grw5s2pf	1263	10	)	)	-RRB-
cord-256444-grw5s2pf	1263	11	.	.	.
cord-256444-grw5s2pf	1264	1	These	these	DT
cord-256444-grw5s2pf	1264	2	viruses	virus	NNS
cord-256444-grw5s2pf	1264	3	often	often	RB
cord-256444-grw5s2pf	1264	4	have	have	VBP
cord-256444-grw5s2pf	1264	5	altered	alter	VBN
cord-256444-grw5s2pf	1264	6	cell	cell	NN
cord-256444-grw5s2pf	1264	7	fusion	fusion	NN
cord-256444-grw5s2pf	1264	8	and	and	CC
cord-256444-grw5s2pf	1264	9	pathogenic	pathogenic	JJ
cord-256444-grw5s2pf	1264	10	properties	property	NNS
cord-256444-grw5s2pf	1264	11	.	.	.
cord-256444-grw5s2pf	1265	1	The	the	DT
cord-256444-grw5s2pf	1265	2	most	most	RBS
cord-256444-grw5s2pf	1265	3	striking	striking	JJ
cord-256444-grw5s2pf	1265	4	effect	effect	NN
cord-256444-grw5s2pf	1265	5	of	of	IN
cord-256444-grw5s2pf	1265	6	deletions	deletion	NNS
cord-256444-grw5s2pf	1265	7	during	during	IN
cord-256444-grw5s2pf	1265	8	natural	natural	JJ
cord-256444-grw5s2pf	1265	9	virus	virus	NN
cord-256444-grw5s2pf	1265	10	infection	infection	NN
cord-256444-grw5s2pf	1265	11	is	be	VBZ
cord-256444-grw5s2pf	1265	12	illustrated	illustrate	VBN
cord-256444-grw5s2pf	1265	13	by	by	IN
cord-256444-grw5s2pf	1265	14	the	the	DT
cord-256444-grw5s2pf	1265	15	emergence	emergence	NN
cord-256444-grw5s2pf	1265	16	of	of	IN
cord-256444-grw5s2pf	1265	17	PRCV	PRCV	NNP
cord-256444-grw5s2pf	1265	18	from	from	IN
cord-256444-grw5s2pf	1265	19	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1265	20	.	.	.
cord-256444-grw5s2pf	1266	1	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1266	2	causes	cause	VBZ
cord-256444-grw5s2pf	1266	3	epizootic	epizootic	JJ
cord-256444-grw5s2pf	1266	4	enteric	enteric	JJ
cord-256444-grw5s2pf	1266	5	infection	infection	NN
cord-256444-grw5s2pf	1266	6	in	in	IN
cord-256444-grw5s2pf	1266	7	pigs	pig	NNS
cord-256444-grw5s2pf	1266	8	,	,	,
cord-256444-grw5s2pf	1266	9	resulting	result	VBG
cord-256444-grw5s2pf	1266	10	in	in	IN
cord-256444-grw5s2pf	1266	11	a	a	DT
cord-256444-grw5s2pf	1266	12	very	very	RB
cord-256444-grw5s2pf	1266	13	high	high	JJ
cord-256444-grw5s2pf	1266	14	mortality	mortality	NN
cord-256444-grw5s2pf	1266	15	rate	rate	NN
cord-256444-grw5s2pf	1266	16	in	in	IN
cord-256444-grw5s2pf	1266	17	newborn	newborn	JJ
cord-256444-grw5s2pf	1266	18	pigs	pig	NNS
cord-256444-grw5s2pf	1266	19	.	.	.
cord-256444-grw5s2pf	1267	1	An	an	DT
cord-256444-grw5s2pf	1267	2	attenuated	attenuated	JJ
cord-256444-grw5s2pf	1267	3	virus	virus	NN
cord-256444-grw5s2pf	1267	4	strain	strain	NN
cord-256444-grw5s2pf	1267	5	that	that	WDT
cord-256444-grw5s2pf	1267	6	is	be	VBZ
cord-256444-grw5s2pf	1267	7	related	relate	VBN
cord-256444-grw5s2pf	1267	8	t	t	NN
cord-256444-grw5s2pf	1267	9	o	o	NN
cord-256444-grw5s2pf	1267	10	TGEV	TGEV	NNS
cord-256444-grw5s2pf	1267	11	but	but	CC
cord-256444-grw5s2pf	1267	12	infects	infect	VBZ
cord-256444-grw5s2pf	1267	13	only	only	RB
cord-256444-grw5s2pf	1267	14	respiratory	respiratory	JJ
cord-256444-grw5s2pf	1267	15	tissues	tissue	NNS
cord-256444-grw5s2pf	1267	16	was	be	VBD
cord-256444-grw5s2pf	1267	17	isolated	isolate	VBN
cord-256444-grw5s2pf	1267	18	in	in	IN
cord-256444-grw5s2pf	1267	19	Western	Western	NNP
cord-256444-grw5s2pf	1267	20	Europe	Europe	NNP
cord-256444-grw5s2pf	1267	21	in	in	IN
cord-256444-grw5s2pf	1267	22	the	the	DT
cord-256444-grw5s2pf	1267	23	early	early	JJ
cord-256444-grw5s2pf	1267	24	1980s	1980s	CD
cord-256444-grw5s2pf	1268	1	(	(	-LRB-
cord-256444-grw5s2pf	1268	2	Pensaertet	Pensaertet	NNP
cord-256444-grw5s2pf	1268	3	al	al	NNP
cord-256444-grw5s2pf	1268	4	.	.	NNP
cord-256444-grw5s2pf	1268	5	,	,	,
cord-256444-grw5s2pf	1268	6	1986	1986	CD
cord-256444-grw5s2pf	1268	7	)	)	-RRB-
cord-256444-grw5s2pf	1268	8	.	.	.
cord-256444-grw5s2pf	1269	1	An	an	DT
cord-256444-grw5s2pf	1269	2	independent	independent	JJ
cord-256444-grw5s2pf	1269	3	isolate	isolate	NN
cord-256444-grw5s2pf	1269	4	of	of	IN
cord-256444-grw5s2pf	1269	5	PRCV	PRCV	NNP
cord-256444-grw5s2pf	1269	6	was	be	VBD
cord-256444-grw5s2pf	1269	7	subsequently	subsequently	RB
cord-256444-grw5s2pf	1269	8	obtained	obtain	VBN
cord-256444-grw5s2pf	1269	9	in	in	IN
cord-256444-grw5s2pf	1269	10	the	the	DT
cord-256444-grw5s2pf	1269	11	United	United	NNP
cord-256444-grw5s2pf	1269	12	States	States	NNP
cord-256444-grw5s2pf	1269	13	(	(	-LRB-
cord-256444-grw5s2pf	1269	14	Wesley	Wesley	NNP
cord-256444-grw5s2pf	1269	15	et	et	NNP
cord-256444-grw5s2pf	1269	16	al	al	NNP
cord-256444-grw5s2pf	1269	17	.	.	NNP
cord-256444-grw5s2pf	1269	18	,	,	,
cord-256444-grw5s2pf	1269	19	1990	1990	CD
cord-256444-grw5s2pf	1269	20	)	)	-RRB-
cord-256444-grw5s2pf	1269	21	.	.	.
cord-256444-grw5s2pf	1270	1	Both	both	DT
cord-256444-grw5s2pf	1270	2	of	of	IN
cord-256444-grw5s2pf	1270	3	these	these	DT
cord-256444-grw5s2pf	1270	4	PRCV	PRCV	NNP
cord-256444-grw5s2pf	1270	5	isolates	isolate	NNS
cord-256444-grw5s2pf	1270	6	have	have	VBP
cord-256444-grw5s2pf	1270	7	similar	similar	JJ
cord-256444-grw5s2pf	1270	8	extents	extent	NNS
cord-256444-grw5s2pf	1270	9	of	of	IN
cord-256444-grw5s2pf	1270	10	deletion	deletion	NN
cord-256444-grw5s2pf	1270	11	in	in	IN
cord-256444-grw5s2pf	1270	12	the	the	DT
cord-256444-grw5s2pf	1270	13	N	n	CD
cord-256444-grw5s2pf	1270	14	terminus	terminus	NN
cord-256444-grw5s2pf	1270	15	of	of	IN
cord-256444-grw5s2pf	1270	16	the	the	DT
cord-256444-grw5s2pf	1270	17	S1	S1	NNP
cord-256444-grw5s2pf	1270	18	protein	protein	NN
cord-256444-grw5s2pf	1270	19	,	,	,
cord-256444-grw5s2pf	1270	20	in	in	IN
cord-256444-grw5s2pf	1270	21	addition	addition	NN
cord-256444-grw5s2pf	1270	22	to	to	IN
cord-256444-grw5s2pf	1270	23	smaller	small	JJR
cord-256444-grw5s2pf	1270	24	deletions	deletion	NNS
cord-256444-grw5s2pf	1270	25	in	in	IN
cord-256444-grw5s2pf	1270	26	gene	gene	NN
cord-256444-grw5s2pf	1270	27	3	3	CD
cord-256444-grw5s2pf	1270	28	,	,	,
cord-256444-grw5s2pf	1270	29	which	which	WDT
cord-256444-grw5s2pf	1270	30	eliminates	eliminate	VBZ
cord-256444-grw5s2pf	1270	31	its	-PRON-	PRP$
cord-256444-grw5s2pf	1270	32	expression	expression	NN
cord-256444-grw5s2pf	1270	33	(	(	-LRB-
cord-256444-grw5s2pf	1270	34	Rasschaert	Rasschaert	NNP
cord-256444-grw5s2pf	1270	35	et	et	FW
cord-256444-grw5s2pf	1270	36	al	al	NNP
cord-256444-grw5s2pf	1270	37	.	.	NNP
cord-256444-grw5s2pf	1270	38	,	,	,
cord-256444-grw5s2pf	1270	39	1990	1990	CD
cord-256444-grw5s2pf	1270	40	;	;	:
cord-256444-grw5s2pf	1270	41	Wesley	Wesley	NNP
cord-256444-grw5s2pf	1270	42	et	et	NNP
cord-256444-grw5s2pf	1270	43	al	al	NNP
cord-256444-grw5s2pf	1270	44	.	.	NNP
cord-256444-grw5s2pf	1270	45	,	,	,
cord-256444-grw5s2pf	1270	46	1991	1991	CD
cord-256444-grw5s2pf	1270	47	;	;	:
cord-256444-grw5s2pf	1270	48	Laude	Laude	NNP
cord-256444-grw5s2pf	1270	49	,	,	,
cord-256444-grw5s2pf	1270	50	1993	1993	CD
cord-256444-grw5s2pf	1270	51	)	)	-RRB-
cord-256444-grw5s2pf	1270	52	.	.	.
cord-256444-grw5s2pf	1271	1	Although	although	IN
cord-256444-grw5s2pf	1271	2	it	-PRON-	PRP
cord-256444-grw5s2pf	1271	3	is	be	VBZ
cord-256444-grw5s2pf	1271	4	not	not	RB
cord-256444-grw5s2pf	1271	5	yet	yet	RB
cord-256444-grw5s2pf	1271	6	possible	possible	JJ
cord-256444-grw5s2pf	1271	7	to	to	TO
cord-256444-grw5s2pf	1271	8	link	link	VB
cord-256444-grw5s2pf	1271	9	the	the	DT
cord-256444-grw5s2pf	1271	10	changes	change	NNS
cord-256444-grw5s2pf	1271	11	in	in	IN
cord-256444-grw5s2pf	1271	12	viral	viral	JJ
cord-256444-grw5s2pf	1271	13	pathogenicity	pathogenicity	NN
cord-256444-grw5s2pf	1271	14	to	to	IN
cord-256444-grw5s2pf	1271	15	the	the	DT
cord-256444-grw5s2pf	1271	16	deletions	deletion	NNS
cord-256444-grw5s2pf	1271	17	in	in	IN
cord-256444-grw5s2pf	1271	18	the	the	DT
cord-256444-grw5s2pf	1271	19	S	S	NNP
cord-256444-grw5s2pf	1271	20	gene	gene	NN
cord-256444-grw5s2pf	1271	21	or	or	CC
cord-256444-grw5s2pf	1271	22	gene	gene	NN
cord-256444-grw5s2pf	1271	23	3	3	CD
cord-256444-grw5s2pf	1271	24	,	,	,
cord-256444-grw5s2pf	1271	25	the	the	DT
cord-256444-grw5s2pf	1271	26	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1271	27	-	-	HYPH
cord-256444-grw5s2pf	1271	28	PRCV	PRCV	NNP
cord-256444-grw5s2pf	1271	29	evolution	evolution	NN
cord-256444-grw5s2pf	1271	30	illustrates	illustrate	VBZ
cord-256444-grw5s2pf	1271	31	the	the	DT
cord-256444-grw5s2pf	1271	32	power	power	NN
cord-256444-grw5s2pf	1271	33	of	of	IN
cord-256444-grw5s2pf	1271	34	deletions	deletion	NNS
cord-256444-grw5s2pf	1271	35	in	in	IN
cord-256444-grw5s2pf	1271	36	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1271	37	evolution	evolution	NN
cord-256444-grw5s2pf	1271	38	.	.	.
cord-256444-grw5s2pf	1272	1	Different	different	JJ
cord-256444-grw5s2pf	1272	2	ts	ts	NN
cord-256444-grw5s2pf	1272	3	mutants	mutant	NNS
cord-256444-grw5s2pf	1272	4	with	with	IN
cord-256444-grw5s2pf	1272	5	defects	defect	NNS
cord-256444-grw5s2pf	1272	6	in	in	IN
cord-256444-grw5s2pf	1272	7	different	different	JJ
cord-256444-grw5s2pf	1272	8	coronaviral	coronaviral	JJ
cord-256444-grw5s2pf	1272	9	genes	gene	NNS
cord-256444-grw5s2pf	1272	10	have	have	VBP
cord-256444-grw5s2pf	1272	11	been	be	VBN
cord-256444-grw5s2pf	1272	12	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	1272	13	to	to	TO
cord-256444-grw5s2pf	1272	14	complement	complement	VB
cord-256444-grw5s2pf	1272	15	each	each	DT
cord-256444-grw5s2pf	1272	16	other	other	JJ
cord-256444-grw5s2pf	1272	17	.	.	.
cord-256444-grw5s2pf	1273	1	The	the	DT
cord-256444-grw5s2pf	1273	2	available	available	JJ
cord-256444-grw5s2pf	1273	3	ts	ts	NN
cord-256444-grw5s2pf	1273	4	mutants	mutant	NNS
cord-256444-grw5s2pf	1273	5	of	of	IN
cord-256444-grw5s2pf	1273	6	MHV	MHV	NNP
cord-256444-grw5s2pf	1273	7	have	have	VBP
cord-256444-grw5s2pf	1273	8	been	be	VBN
cord-256444-grw5s2pf	1273	9	divided	divide	VBN
cord-256444-grw5s2pf	1273	10	into	into	IN
cord-256444-grw5s2pf	1273	11	at	at	RB
cord-256444-grw5s2pf	1273	12	least	least	RBS
cord-256444-grw5s2pf	1273	13	seven	seven	CD
cord-256444-grw5s2pf	1273	14	complementation	complementation	NN
cord-256444-grw5s2pf	1273	15	groups	group	NNS
cord-256444-grw5s2pf	1273	16	,	,	,
cord-256444-grw5s2pf	1273	17	five	five	CD
cord-256444-grw5s2pf	1273	18	of	of	IN
cord-256444-grw5s2pf	1273	19	which	which	WDT
cord-256444-grw5s2pf	1273	20	have	have	VBP
cord-256444-grw5s2pf	1273	21	an	an	DT
cord-256444-grw5s2pf	1273	22	RNA	RNA	NNP
cord-256444-grw5s2pf	1273	23	(	(	-LRB-
cord-256444-grw5s2pf	1273	24	-phenotype	-phenotype	.
cord-256444-grw5s2pf	1274	1	(	(	-LRB-
cord-256444-grw5s2pf	1274	2	Leibowitz	Leibowitz	NNP
cord-256444-grw5s2pf	1274	3	et	et	NNP
cord-256444-grw5s2pf	1274	4	al	al	NNP
cord-256444-grw5s2pf	1274	5	.	.	NNP
cord-256444-grw5s2pf	1274	6	,	,	,
cord-256444-grw5s2pf	1274	7	1982a	1982a	CD
cord-256444-grw5s2pf	1274	8	)	)	-RRB-
cord-256444-grw5s2pf	1275	1	(	(	-LRB-
cord-256444-grw5s2pf	1275	2	Fig	Fig	NNP
cord-256444-grw5s2pf	1275	3	.	.	.
cord-256444-grw5s2pf	1275	4	 	 	_SP
cord-256444-grw5s2pf	1275	5	6	6	CD
cord-256444-grw5s2pf	1275	6	)	)	-RRB-
cord-256444-grw5s2pf	1275	7	.	.	.
cord-256444-grw5s2pf	1276	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1276	2	is	be	VBZ
cord-256444-grw5s2pf	1276	3	worth	worth	JJ
cord-256444-grw5s2pf	1276	4	noting	note	VBG
cord-256444-grw5s2pf	1276	5	that	that	IN
cord-256444-grw5s2pf	1276	6	these	these	DT
cord-256444-grw5s2pf	1276	7	five	five	CD
cord-256444-grw5s2pf	1276	8	RNA	RNA	NNP
cord-256444-grw5s2pf	1276	9	(	(	-LRB-
cord-256444-grw5s2pf	1276	10	-	-	:
cord-256444-grw5s2pf	1276	11	)	)	-RRB-
cord-256444-grw5s2pf	1276	12	complementation	complementation	NN
cord-256444-grw5s2pf	1276	13	groups	group	NNS
cord-256444-grw5s2pf	1276	14	have	have	VBP
cord-256444-grw5s2pf	1276	15	been	be	VBN
cord-256444-grw5s2pf	1276	16	mapped	map	VBN
cord-256444-grw5s2pf	1276	17	in	in	IN
cord-256444-grw5s2pf	1276	18	gene	gene	NN
cord-256444-grw5s2pf	1276	19	1	1	CD
cord-256444-grw5s2pf	1276	20	,	,	,
cord-256444-grw5s2pf	1276	21	which	which	WDT
cord-256444-grw5s2pf	1276	22	is	be	VBZ
cord-256444-grw5s2pf	1276	23	translated	translate	VBN
cord-256444-grw5s2pf	1276	24	into	into	IN
cord-256444-grw5s2pf	1276	25	a	a	DT
cord-256444-grw5s2pf	1276	26	polyprotein	polyprotein	NN
cord-256444-grw5s2pf	1276	27	.	.	.
cord-256444-grw5s2pf	1277	1	The	the	DT
cord-256444-grw5s2pf	1277	2	existence	existence	NN
cord-256444-grw5s2pf	1277	3	of	of	IN
cord-256444-grw5s2pf	1277	4	five	five	CD
cord-256444-grw5s2pf	1277	5	complementation	complementation	NN
cord-256444-grw5s2pf	1277	6	groups	group	NNS
cord-256444-grw5s2pf	1277	7	within	within	IN
cord-256444-grw5s2pf	1277	8	this	this	DT
cord-256444-grw5s2pf	1277	9	gene	gene	NN
cord-256444-grw5s2pf	1277	10	indicates	indicate	VBZ
cord-256444-grw5s2pf	1277	11	that	that	IN
cord-256444-grw5s2pf	1277	12	this	this	DT
cord-256444-grw5s2pf	1277	13	polyprotein	polyprotein	NN
cord-256444-grw5s2pf	1277	14	is	be	VBZ
cord-256444-grw5s2pf	1277	15	processed	process	VBN
cord-256444-grw5s2pf	1277	16	into	into	IN
cord-256444-grw5s2pf	1277	17	at	at	RB
cord-256444-grw5s2pf	1277	18	least	least	RBS
cord-256444-grw5s2pf	1277	19	five	five	CD
cord-256444-grw5s2pf	1277	20	different	different	JJ
cord-256444-grw5s2pf	1277	21	proteins	protein	NNS
cord-256444-grw5s2pf	1277	22	that	that	WDT
cord-256444-grw5s2pf	1277	23	function	function	VBP
cord-256444-grw5s2pf	1277	24	independently	independently	RB
cord-256444-grw5s2pf	1277	25	.	.	.
cord-256444-grw5s2pf	1278	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1278	2	is	be	VBZ
cord-256444-grw5s2pf	1278	3	not	not	RB
cord-256444-grw5s2pf	1278	4	possible	possible	JJ
cord-256444-grw5s2pf	1278	5	,	,	,
cord-256444-grw5s2pf	1278	6	however	however	RB
cord-256444-grw5s2pf	1278	7	,	,	,
cord-256444-grw5s2pf	1278	8	to	to	TO
cord-256444-grw5s2pf	1278	9	complement	complement	VB
cord-256444-grw5s2pf	1278	10	the	the	DT
cord-256444-grw5s2pf	1278	11	genetic	genetic	JJ
cord-256444-grw5s2pf	1278	12	defects	defect	NNS
cord-256444-grw5s2pf	1278	13	of	of	IN
cord-256444-grw5s2pf	1278	14	a	a	DT
cord-256444-grw5s2pf	1278	15	virus	virus	NN
cord-256444-grw5s2pf	1278	16	by	by	IN
cord-256444-grw5s2pf	1278	17	expressing	express	VBG
cord-256444-grw5s2pf	1278	18	a	a	DT
cord-256444-grw5s2pf	1278	19	wildtype	wildtype	JJ
cord-256444-grw5s2pf	1278	20	viral	viral	JJ
cord-256444-grw5s2pf	1278	21	protein	protein	NN
cord-256444-grw5s2pf	1278	22	from	from	IN
cord-256444-grw5s2pf	1278	23	an	an	DT
cord-256444-grw5s2pf	1278	24	exogenous	exogenous	JJ
cord-256444-grw5s2pf	1278	25	vector	vector	NN
cord-256444-grw5s2pf	1278	26	.	.	.
cord-256444-grw5s2pf	1279	1	Mixed	mixed	JJ
cord-256444-grw5s2pf	1279	2	infection	infection	NN
cord-256444-grw5s2pf	1279	3	with	with	IN
cord-256444-grw5s2pf	1279	4	MHV	mhv	NN
cord-256444-grw5s2pf	1279	5	and	and	CC
cord-256444-grw5s2pf	1279	6	murine	murine	JJ
cord-256444-grw5s2pf	1279	7	leukemia	leukemia	NN
cord-256444-grw5s2pf	1279	8	virus	virus	NN
cord-256444-grw5s2pf	1279	9	in	in	IN
cord-256444-grw5s2pf	1279	10	tissue	tissue	NN
cord-256444-grw5s2pf	1279	11	culture	culture	NN
cord-256444-grw5s2pf	1279	12	cells	cell	NNS
cord-256444-grw5s2pf	1279	13	yielded	yield	VBD
cord-256444-grw5s2pf	1279	14	a	a	DT
cord-256444-grw5s2pf	1279	15	pseudotype	pseudotype	NN
cord-256444-grw5s2pf	1279	16	MHV	MHV	NNP
cord-256444-grw5s2pf	1279	17	which	which	WDT
cord-256444-grw5s2pf	1279	18	contained	contain	VBD
cord-256444-grw5s2pf	1279	19	a	a	DT
cord-256444-grw5s2pf	1279	20	murine	murine	JJ
cord-256444-grw5s2pf	1279	21	leukemia	leukemia	NN
cord-256444-grw5s2pf	1279	22	virus	virus	NN
cord-256444-grw5s2pf	1279	23	envelope	envelope	NN
cord-256444-grw5s2pf	1279	24	protein	protein	NN
cord-256444-grw5s2pf	1279	25	and	and	CC
cord-256444-grw5s2pf	1279	26	was	be	VBD
cord-256444-grw5s2pf	1279	27	neutralized	neutralize	VBN
cord-256444-grw5s2pf	1279	28	by	by	IN
cord-256444-grw5s2pf	1279	29	antibodies	antibody	NNS
cord-256444-grw5s2pf	1279	30	against	against	IN
cord-256444-grw5s2pf	1279	31	both	both	CC
cord-256444-grw5s2pf	1279	32	murine	murine	JJ
cord-256444-grw5s2pf	1279	33	leukemia	leukemia	NN
cord-256444-grw5s2pf	1279	34	virus	virus	NN
cord-256444-grw5s2pf	1279	35	and	and	CC
cord-256444-grw5s2pf	1279	36	MHV	MHV	NNP
cord-256444-grw5s2pf	1279	37	(	(	-LRB-
cord-256444-grw5s2pf	1279	38	Yoshikura	Yoshikura	NNP
cord-256444-grw5s2pf	1279	39	and	and	CC
cord-256444-grw5s2pf	1279	40	Taguchi	Taguchi	NNP
cord-256444-grw5s2pf	1279	41	,	,	,
cord-256444-grw5s2pf	1279	42	1978	1978	CD
cord-256444-grw5s2pf	1279	43	)	)	-RRB-
cord-256444-grw5s2pf	1279	44	.	.	.
cord-256444-grw5s2pf	1280	1	This	this	DT
cord-256444-grw5s2pf	1280	2	phenotypic	phenotypic	NN
cord-256444-grw5s2pf	1280	3	mixing	mixing	NN
cord-256444-grw5s2pf	1280	4	of	of	IN
cord-256444-grw5s2pf	1280	5	viral	viral	JJ
cord-256444-grw5s2pf	1280	6	proteins	protein	NNS
cord-256444-grw5s2pf	1280	7	suggests	suggest	VBZ
cord-256444-grw5s2pf	1280	8	the	the	DT
cord-256444-grw5s2pf	1280	9	lack	lack	NN
cord-256444-grw5s2pf	1280	10	of	of	IN
cord-256444-grw5s2pf	1280	11	a	a	DT
cord-256444-grw5s2pf	1280	12	stringent	stringent	JJ
cord-256444-grw5s2pf	1280	13	requirement	requirement	NN
cord-256444-grw5s2pf	1280	14	for	for	IN
cord-256444-grw5s2pf	1280	15	a	a	DT
cord-256444-grw5s2pf	1280	16	virus	virus	NN
cord-256444-grw5s2pf	1280	17	-	-	HYPH
cord-256444-grw5s2pf	1280	18	specific	specific	JJ
cord-256444-grw5s2pf	1280	19	spike	spike	NN
cord-256444-grw5s2pf	1280	20	protein	protein	NN
cord-256444-grw5s2pf	1280	21	for	for	IN
cord-256444-grw5s2pf	1280	22	the	the	DT
cord-256444-grw5s2pf	1280	23	formation	formation	NN
cord-256444-grw5s2pf	1280	24	of	of	IN
cord-256444-grw5s2pf	1280	25	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1280	26	particles	particle	NNS
cord-256444-grw5s2pf	1280	27	.	.	.
cord-256444-grw5s2pf	1281	1	Pseudotype	Pseudotype	NNP
cord-256444-grw5s2pf	1281	2	formation	formation	NN
cord-256444-grw5s2pf	1281	3	of	of	IN
cord-256444-grw5s2pf	1281	4	virus	virus	NN
cord-256444-grw5s2pf	1281	5	particles	particle	NNS
cord-256444-grw5s2pf	1281	6	has	have	VBZ
cord-256444-grw5s2pf	1281	7	also	also	RB
cord-256444-grw5s2pf	1281	8	been	be	VBN
cord-256444-grw5s2pf	1281	9	achieved	achieve	VBN
cord-256444-grw5s2pf	1281	10	by	by	IN
cord-256444-grw5s2pf	1281	11	expressing	express	VBG
cord-256444-grw5s2pf	1281	12	a	a	DT
cord-256444-grw5s2pf	1281	13	viral	viral	JJ
cord-256444-grw5s2pf	1281	14	protein	protein	NN
cord-256444-grw5s2pf	1281	15	,	,	,
cord-256444-grw5s2pf	1281	16	e.g.	e.g.	RB
cord-256444-grw5s2pf	1281	17	,	,	,
cord-256444-grw5s2pf	1281	18	HE	HE	NNP
cord-256444-grw5s2pf	1281	19	protein	protein	NN
cord-256444-grw5s2pf	1281	20	,	,	,
cord-256444-grw5s2pf	1281	21	from	from	IN
cord-256444-grw5s2pf	1281	22	a	a	DT
cord-256444-grw5s2pf	1281	23	DI	DI	NNP
cord-256444-grw5s2pf	1281	24	RNA	RNA	NNP
cord-256444-grw5s2pf	1281	25	vector	vector	NN
cord-256444-grw5s2pf	1281	26	(	(	-LRB-
cord-256444-grw5s2pf	1281	27	see	see	VB
cord-256444-grw5s2pf	1281	28	Section	section	NN
cord-256444-grw5s2pf	1281	29	VI	VI	NNP
cord-256444-grw5s2pf	1281	30	,	,	,
cord-256444-grw5s2pf	1281	31	E	E	NNP
cord-256444-grw5s2pf	1281	32	)	)	-RRB-
cord-256444-grw5s2pf	1281	33	,	,	,
cord-256444-grw5s2pf	1281	34	which	which	WDT
cord-256444-grw5s2pf	1281	35	was	be	VBD
cord-256444-grw5s2pf	1281	36	incorporated	incorporate	VBN
cord-256444-grw5s2pf	1281	37	into	into	IN
cord-256444-grw5s2pf	1281	38	virus	virus	NN
cord-256444-grw5s2pf	1281	39	particles	particle	NNS
cord-256444-grw5s2pf	1281	40	.	.	.
cord-256444-grw5s2pf	1282	1	One	one	CD
cord-256444-grw5s2pf	1282	2	unique	unique	JJ
cord-256444-grw5s2pf	1282	3	genetic	genetic	JJ
cord-256444-grw5s2pf	1282	4	feature	feature	NN
cord-256444-grw5s2pf	1282	5	of	of	IN
cord-256444-grw5s2pf	1282	6	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1282	7	is	be	VBZ
cord-256444-grw5s2pf	1282	8	their	-PRON-	PRP$
cord-256444-grw5s2pf	1282	9	ability	ability	NN
cord-256444-grw5s2pf	1282	10	to	to	TO
cord-256444-grw5s2pf	1282	11	undergo	undergo	VB
cord-256444-grw5s2pf	1282	12	RNA	RNA	NNP
cord-256444-grw5s2pf	1282	13	recombination	recombination	NN
cord-256444-grw5s2pf	1282	14	at	at	IN
cord-256444-grw5s2pf	1282	15	a	a	DT
cord-256444-grw5s2pf	1282	16	very	very	RB
cord-256444-grw5s2pf	1282	17	high	high	JJ
cord-256444-grw5s2pf	1282	18	frequency	frequency	NN
cord-256444-grw5s2pf	1282	19	;	;	:
cord-256444-grw5s2pf	1282	20	this	this	DT
cord-256444-grw5s2pf	1282	21	is	be	VBZ
cord-256444-grw5s2pf	1282	22	particularly	particularly	RB
cord-256444-grw5s2pf	1282	23	true	true	JJ
cord-256444-grw5s2pf	1282	24	of	of	IN
cord-256444-grw5s2pf	1282	25	MHV	MHV	NNP
cord-256444-grw5s2pf	1282	26	,	,	,
cord-256444-grw5s2pf	1282	27	in	in	IN
cord-256444-grw5s2pf	1282	28	which	which	WDT
cord-256444-grw5s2pf	1282	29	recombinant	recombinant	JJ
cord-256444-grw5s2pf	1282	30	viruses	virus	NNS
cord-256444-grw5s2pf	1282	31	containing	contain	VBG
cord-256444-grw5s2pf	1282	32	parts	part	NNS
cord-256444-grw5s2pf	1282	33	of	of	IN
cord-256444-grw5s2pf	1282	34	the	the	DT
cord-256444-grw5s2pf	1282	35	genomic	genomic	JJ
cord-256444-grw5s2pf	1282	36	sequences	sequence	NNS
cord-256444-grw5s2pf	1282	37	of	of	IN
cord-256444-grw5s2pf	1282	38	both	both	DT
cord-256444-grw5s2pf	1282	39	parental	parental	JJ
cord-256444-grw5s2pf	1282	40	viruses	virus	NNS
cord-256444-grw5s2pf	1282	41	could	could	MD
cord-256444-grw5s2pf	1282	42	be	be	VB
cord-256444-grw5s2pf	1282	43	isolated	isolate	VBN
cord-256444-grw5s2pf	1282	44	at	at	IN
cord-256444-grw5s2pf	1282	45	high	high	JJ
cord-256444-grw5s2pf	1282	46	frequency	frequency	NN
cord-256444-grw5s2pf	1282	47	when	when	WRB
cord-256444-grw5s2pf	1282	48	two	two	CD
cord-256444-grw5s2pf	1282	49	strains	strain	NNS
cord-256444-grw5s2pf	1282	50	of	of	IN
cord-256444-grw5s2pf	1282	51	MHV	MHV	NNP
cord-256444-grw5s2pf	1282	52	with	with	IN
cord-256444-grw5s2pf	1282	53	defined	define	VBN
cord-256444-grw5s2pf	1282	54	genetic	genetic	JJ
cord-256444-grw5s2pf	1282	55	markers	marker	NNS
cord-256444-grw5s2pf	1282	56	were	be	VBD
cord-256444-grw5s2pf	1282	57	co	co	JJ
cord-256444-grw5s2pf	1282	58	-	-	JJ
cord-256444-grw5s2pf	1282	59	infected	infect	VBN
cord-256444-grw5s2pf	1282	60	into	into	IN
cord-256444-grw5s2pf	1282	61	culture	culture	NN
cord-256444-grw5s2pf	1282	62	cells	cell	NNS
cord-256444-grw5s2pf	1282	63	or	or	CC
cord-256444-grw5s2pf	1282	64	animals	animal	NNS
cord-256444-grw5s2pf	1282	65	.	.	.
cord-256444-grw5s2pf	1283	1	This	this	DT
cord-256444-grw5s2pf	1283	2	genetic	genetic	JJ
cord-256444-grw5s2pf	1283	3	phenomenon	phenomenon	NN
cord-256444-grw5s2pf	1283	4	was	be	VBD
cord-256444-grw5s2pf	1283	5	first	first	RB
cord-256444-grw5s2pf	1283	6	discovered	discover	VBN
cord-256444-grw5s2pf	1283	7	using	use	VBG
cord-256444-grw5s2pf	1283	8	two	two	CD
cord-256444-grw5s2pf	1283	9	ts	t	NNS
cord-256444-grw5s2pf	1283	10	mutants	mutant	NNS
cord-256444-grw5s2pf	1283	11	of	of	IN
cord-256444-grw5s2pf	1283	12	MHV	MHV	NNP
cord-256444-grw5s2pf	1283	13	.	.	.
cord-256444-grw5s2pf	1284	1	Subsequently	subsequently	RB
cord-256444-grw5s2pf	1284	2	,	,	,
cord-256444-grw5s2pf	1284	3	many	many	JJ
cord-256444-grw5s2pf	1284	4	different	different	JJ
cord-256444-grw5s2pf	1284	5	recombinant	recombinant	JJ
cord-256444-grw5s2pf	1284	6	MHVs	MHVs	NNP
cord-256444-grw5s2pf	1284	7	were	be	VBD
cord-256444-grw5s2pf	1284	8	isolated	isolate	VBN
cord-256444-grw5s2pf	1284	9	(	(	-LRB-
cord-256444-grw5s2pf	1284	10	Keck	Keck	NNP
cord-256444-grw5s2pf	1284	11	et	et	NNP
cord-256444-grw5s2pf	1284	12	al	al	NNP
cord-256444-grw5s2pf	1284	13	.	.	NNP
cord-256444-grw5s2pf	1284	14	,	,	,
cord-256444-grw5s2pf	1285	1	,	,	,
cord-256444-grw5s2pf	1285	2	1988b	1988b	CD
cord-256444-grw5s2pf	1285	3	Makino	Makino	NNP
cord-256444-grw5s2pf	1285	4	et	et	NNP
cord-256444-grw5s2pf	1285	5	al	al	NNP
cord-256444-grw5s2pf	1285	6	.	.	NNP
cord-256444-grw5s2pf	1285	7	,	,	,
cord-256444-grw5s2pf	1285	8	1987	1987	CD
cord-256444-grw5s2pf	1285	9	)	)	-RRB-
cord-256444-grw5s2pf	1285	10	using	use	VBG
cord-256444-grw5s2pf	1285	11	a	a	DT
cord-256444-grw5s2pf	1285	12	combination	combination	NN
cord-256444-grw5s2pf	1285	13	of	of	IN
cord-256444-grw5s2pf	1285	14	selection	selection	NN
cord-256444-grw5s2pf	1285	15	markers	marker	NNS
cord-256444-grw5s2pf	1285	16	,	,	,
cord-256444-grw5s2pf	1285	17	such	such	JJ
cord-256444-grw5s2pf	1285	18	as	as	IN
cord-256444-grw5s2pf	1285	19	ts	ts	NNP
cord-256444-grw5s2pf	1285	20	markers	marker	NNS
cord-256444-grw5s2pf	1285	21	,	,	,
cord-256444-grw5s2pf	1285	22	resistance	resistance	NN
cord-256444-grw5s2pf	1285	23	to	to	IN
cord-256444-grw5s2pf	1285	24	neutralizing	neutralize	VBG
cord-256444-grw5s2pf	1285	25	antibodies	antibody	NNS
cord-256444-grw5s2pf	1285	26	,	,	,
cord-256444-grw5s2pf	1285	27	and	and	CC
cord-256444-grw5s2pf	1285	28	cytopathic	cytopathic	JJ
cord-256444-grw5s2pf	1285	29	effects	effect	NNS
cord-256444-grw5s2pf	1285	30	(	(	-LRB-
cord-256444-grw5s2pf	1285	31	the	the	DT
cord-256444-grw5s2pf	1285	32	ability	ability	NN
cord-256444-grw5s2pf	1285	33	of	of	IN
cord-256444-grw5s2pf	1285	34	the	the	DT
cord-256444-grw5s2pf	1285	35	virus	virus	NN
cord-256444-grw5s2pf	1285	36	to	to	TO
cord-256444-grw5s2pf	1285	37	cause	cause	VB
cord-256444-grw5s2pf	1285	38	fusion	fusion	NN
cord-256444-grw5s2pf	1285	39	)	)	-RRB-
cord-256444-grw5s2pf	1285	40	.	.	.
cord-256444-grw5s2pf	1286	1	Based	base	VBN
cord-256444-grw5s2pf	1286	2	on	on	IN
cord-256444-grw5s2pf	1286	3	the	the	DT
cord-256444-grw5s2pf	1286	4	distribution	distribution	NN
cord-256444-grw5s2pf	1286	5	of	of	IN
cord-256444-grw5s2pf	1286	6	the	the	DT
cord-256444-grw5s2pf	1286	7	crossover	crossover	NN
cord-256444-grw5s2pf	1286	8	sites	site	NNS
cord-256444-grw5s2pf	1286	9	on	on	IN
cord-256444-grw5s2pf	1286	10	the	the	DT
cord-256444-grw5s2pf	1286	11	viral	viral	JJ
cord-256444-grw5s2pf	1286	12	RNA	RNA	NNP
cord-256444-grw5s2pf	1286	13	genome	genome	NN
cord-256444-grw5s2pf	1286	14	,	,	,
cord-256444-grw5s2pf	1286	15	it	-PRON-	PRP
cord-256444-grw5s2pf	1286	16	appears	appear	VBZ
cord-256444-grw5s2pf	1286	17	that	that	IN
cord-256444-grw5s2pf	1286	18	recombination	recombination	NN
cord-256444-grw5s2pf	1286	19	can	can	MD
cord-256444-grw5s2pf	1286	20	occur	occur	VB
cord-256444-grw5s2pf	1286	21	practically	practically	RB
cord-256444-grw5s2pf	1286	22	anywhere	anywhere	RB
cord-256444-grw5s2pf	1286	23	on	on	IN
cord-256444-grw5s2pf	1286	24	the	the	DT
cord-256444-grw5s2pf	1286	25	viral	viral	JJ
cord-256444-grw5s2pf	1286	26	genome	genome	NN
cord-256444-grw5s2pf	1286	27	,	,	,
cord-256444-grw5s2pf	1286	28	although	although	IN
cord-256444-grw5s2pf	1286	29	some	some	DT
cord-256444-grw5s2pf	1286	30	combinations	combination	NNS
cord-256444-grw5s2pf	1286	31	of	of	IN
cord-256444-grw5s2pf	1286	32	virus	virus	NN
cord-256444-grw5s2pf	1286	33	strains	strain	VBZ
cord-256444-grw5s2pf	1286	34	favor	favor	VBP
cord-256444-grw5s2pf	1286	35	selection	selection	NN
cord-256444-grw5s2pf	1286	36	of	of	IN
cord-256444-grw5s2pf	1286	37	viruses	virus	NNS
cord-256444-grw5s2pf	1286	38	with	with	IN
cord-256444-grw5s2pf	1286	39	certain	certain	JJ
cord-256444-grw5s2pf	1286	40	recombination	recombination	NN
cord-256444-grw5s2pf	1286	41	sites	site	NNS
cord-256444-grw5s2pf	1286	42	(	(	-LRB-
cord-256444-grw5s2pf	1286	43	Lai	Lai	NNP
cord-256444-grw5s2pf	1286	44	,	,	,
cord-256444-grw5s2pf	1286	45	1992	1992	CD
cord-256444-grw5s2pf	1286	46	)	)	-RRB-
cord-256444-grw5s2pf	1286	47	.	.	.
cord-256444-grw5s2pf	1287	1	For	for	IN
cord-256444-grw5s2pf	1287	2	example	example	NN
cord-256444-grw5s2pf	1287	3	,	,	,
cord-256444-grw5s2pf	1287	4	between	between	IN
cord-256444-grw5s2pf	1287	5	the	the	DT
cord-256444-grw5s2pf	1287	6	MHV	MHV	NNP
cord-256444-grw5s2pf	1287	7	A59	A59	NNP
cord-256444-grw5s2pf	1287	8	and	and	CC
cord-256444-grw5s2pf	1287	9	JHM	JHM	NNP
cord-256444-grw5s2pf	1287	10	strains	strain	NNS
cord-256444-grw5s2pf	1287	11	,	,	,
cord-256444-grw5s2pf	1287	12	recombination	recombination	NN
cord-256444-grw5s2pf	1287	13	occurs	occur	VBZ
cord-256444-grw5s2pf	1287	14	mostly	mostly	RB
cord-256444-grw5s2pf	1287	15	at	at	IN
cord-256444-grw5s2pf	1287	16	the	the	DT
cord-256444-grw5s2pf	1287	17	5	5	CD
cord-256444-grw5s2pf	1287	18	'	'	NN
cord-256444-grw5s2pf	1287	19	end	end	NN
cord-256444-grw5s2pf	1287	20	of	of	IN
cord-256444-grw5s2pf	1287	21	the	the	DT
cord-256444-grw5s2pf	1287	22	genome	genome	NN
cord-256444-grw5s2pf	1287	23	and	and	CC
cord-256444-grw5s2pf	1287	24	rarely	rarely	RB
cord-256444-grw5s2pf	1287	25	at	at	IN
cord-256444-grw5s2pf	1287	26	the	the	DT
cord-256444-grw5s2pf	1287	27	3	3	CD
cord-256444-grw5s2pf	1287	28	'	'	''
cord-256444-grw5s2pf	1287	29	end	end	NN
cord-256444-grw5s2pf	1287	30	.	.	.
cord-256444-grw5s2pf	1288	1	In	in	IN
cord-256444-grw5s2pf	1288	2	contrast	contrast	NN
cord-256444-grw5s2pf	1288	3	,	,	,
cord-256444-grw5s2pf	1288	4	recombination	recombination	NN
cord-256444-grw5s2pf	1288	5	between	between	IN
cord-256444-grw5s2pf	1288	6	the	the	DT
cord-256444-grw5s2pf	1288	7	MHV-2	MHV-2	NNP
cord-256444-grw5s2pf	1288	8	and	and	CC
cord-256444-grw5s2pf	1288	9	JHM	JHM	NNP
cord-256444-grw5s2pf	1288	10	strains	strain	NNS
cord-256444-grw5s2pf	1288	11	occurs	occur	VBZ
cord-256444-grw5s2pf	1288	12	readily	readily	RB
cord-256444-grw5s2pf	1288	13	a	a	DT
cord-256444-grw5s2pf	1288	14	t	t	NN
cord-256444-grw5s2pf	1288	15	the	the	DT
cord-256444-grw5s2pf	1288	16	3	3	CD
cord-256444-grw5s2pf	1288	17	'	'	''
cord-256444-grw5s2pf	1288	18	end	end	NN
cord-256444-grw5s2pf	1288	19	.	.	.
cord-256444-grw5s2pf	1289	1	The	the	DT
cord-256444-grw5s2pf	1289	2	most	most	RBS
cord-256444-grw5s2pf	1289	3	surprising	surprising	JJ
cord-256444-grw5s2pf	1289	4	finding	finding	NN
cord-256444-grw5s2pf	1289	5	with	with	IN
cord-256444-grw5s2pf	1289	6	regard	regard	NN
cord-256444-grw5s2pf	1289	7	to	to	IN
cord-256444-grw5s2pf	1289	8	MHV	MHV	NNP
cord-256444-grw5s2pf	1289	9	recombination	recombination	NN
cord-256444-grw5s2pf	1289	10	is	be	VBZ
cord-256444-grw5s2pf	1289	11	the	the	DT
cord-256444-grw5s2pf	1289	12	extremely	extremely	RB
cord-256444-grw5s2pf	1289	13	high	high	JJ
cord-256444-grw5s2pf	1289	14	frequency	frequency	NN
cord-256444-grw5s2pf	1289	15	of	of	IN
cord-256444-grw5s2pf	1289	16	recombination	recombination	NN
cord-256444-grw5s2pf	1289	17	,	,	,
cord-256444-grw5s2pf	1289	18	which	which	WDT
cord-256444-grw5s2pf	1289	19	has	have	VBZ
cord-256444-grw5s2pf	1289	20	been	be	VBN
cord-256444-grw5s2pf	1289	21	calculated	calculate	VBN
cord-256444-grw5s2pf	1289	22	to	to	TO
cord-256444-grw5s2pf	1289	23	be	be	VB
cord-256444-grw5s2pf	1289	24	nearly	nearly	RB
cord-256444-grw5s2pf	1289	25	25	25	CD
cord-256444-grw5s2pf	1289	26	%	%	NN
cord-256444-grw5s2pf	1289	27	for	for	IN
cord-256444-grw5s2pf	1289	28	the	the	DT
cord-256444-grw5s2pf	1289	29	entire	entire	JJ
cord-256444-grw5s2pf	1289	30	MHV	MHV	NNP
cord-256444-grw5s2pf	1289	31	genome	genome	NN
cord-256444-grw5s2pf	1289	32	.	.	.
cord-256444-grw5s2pf	1290	1	This	this	DT
cord-256444-grw5s2pf	1290	2	high	high	JJ
cord-256444-grw5s2pf	1290	3	frequency	frequency	NN
cord-256444-grw5s2pf	1290	4	of	of	IN
cord-256444-grw5s2pf	1290	5	recombination	recombination	NN
cord-256444-grw5s2pf	1290	6	is	be	VBZ
cord-256444-grw5s2pf	1290	7	reminiscent	reminiscent	JJ
cord-256444-grw5s2pf	1290	8	of	of	IN
cord-256444-grw5s2pf	1290	9	the	the	DT
cord-256444-grw5s2pf	1290	10	reassortment	reassortment	NN
cord-256444-grw5s2pf	1290	11	of	of	IN
cord-256444-grw5s2pf	1290	12	segmented	segmented	JJ
cord-256444-grw5s2pf	1290	13	RNA	RNA	NNP
cord-256444-grw5s2pf	1290	14	genomes	genome	NNS
cord-256444-grw5s2pf	1290	15	in	in	IN
cord-256444-grw5s2pf	1290	16	viruses	virus	NNS
cord-256444-grw5s2pf	1290	17	such	such	JJ
cord-256444-grw5s2pf	1290	18	as	as	IN
cord-256444-grw5s2pf	1290	19	influenza	influenza	NN
cord-256444-grw5s2pf	1290	20	virus	virus	NN
cord-256444-grw5s2pf	1290	21	and	and	CC
cord-256444-grw5s2pf	1290	22	reovirus	reovirus	NNP
cord-256444-grw5s2pf	1290	23	.	.	.
cord-256444-grw5s2pf	1291	1	The	the	DT
cord-256444-grw5s2pf	1291	2	recombination	recombination	NN
cord-256444-grw5s2pf	1291	3	map	map	NN
cord-256444-grw5s2pf	1291	4	for	for	IN
cord-256444-grw5s2pf	1291	5	MHV	MHV	NNP
cord-256444-grw5s2pf	1291	6	is	be	VBZ
cord-256444-grw5s2pf	1291	7	nearly	nearly	RB
cord-256444-grw5s2pf	1291	8	linear	linear	JJ
cord-256444-grw5s2pf	1291	9	,	,	,
cord-256444-grw5s2pf	1291	10	suggesting	suggest	VBG
cord-256444-grw5s2pf	1291	11	the	the	DT
cord-256444-grw5s2pf	1291	12	random	random	JJ
cord-256444-grw5s2pf	1291	13	occurrence	occurrence	NN
cord-256444-grw5s2pf	1291	14	of	of	IN
cord-256444-grw5s2pf	1291	15	recombination	recombination	NN
cord-256444-grw5s2pf	1291	16	;	;	:
cord-256444-grw5s2pf	1291	17	however	however	RB
cord-256444-grw5s2pf	1291	18	,	,	,
cord-256444-grw5s2pf	1291	19	more	more	RBR
cord-256444-grw5s2pf	1291	20	careful	careful	JJ
cord-256444-grw5s2pf	1291	21	analysis	analysis	NN
cord-256444-grw5s2pf	1291	22	of	of	IN
cord-256444-grw5s2pf	1291	23	the	the	DT
cord-256444-grw5s2pf	1291	24	recombination	recombination	NN
cord-256444-grw5s2pf	1291	25	frequency	frequency	NN
cord-256444-grw5s2pf	1291	26	showed	show	VBD
cord-256444-grw5s2pf	1291	27	that	that	IN
cord-256444-grw5s2pf	1291	28	there	there	EX
cord-256444-grw5s2pf	1291	29	is	be	VBZ
cord-256444-grw5s2pf	1291	30	an	an	DT
cord-256444-grw5s2pf	1291	31	increasing	increase	VBG
cord-256444-grw5s2pf	1291	32	gradient	gradient	NN
cord-256444-grw5s2pf	1291	33	of	of	IN
cord-256444-grw5s2pf	1291	34	recombination	recombination	NN
cord-256444-grw5s2pf	1291	35	frequency	frequency	NN
cord-256444-grw5s2pf	1291	36	(	(	-LRB-
cord-256444-grw5s2pf	1291	37	in	in	IN
cord-256444-grw5s2pf	1291	38	the	the	DT
cord-256444-grw5s2pf	1291	39	direction	direction	NN
cord-256444-grw5s2pf	1291	40	of	of	IN
cord-256444-grw5s2pf	1291	41	5'+3	5'+3	CD
cord-256444-grw5s2pf	1291	42	'	'	''
cord-256444-grw5s2pf	1291	43	)	)	-RRB-
cord-256444-grw5s2pf	1292	1	across	across	IN
cord-256444-grw5s2pf	1292	2	the	the	DT
cord-256444-grw5s2pf	1292	3	genome	genome	NN
cord-256444-grw5s2pf	1292	4	,	,	,
cord-256444-grw5s2pf	1292	5	suggesting	suggest	VBG
cord-256444-grw5s2pf	1292	6	that	that	IN
cord-256444-grw5s2pf	1292	7	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1292	8	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	1292	9	,	,	,
cord-256444-grw5s2pf	1292	10	which	which	WDT
cord-256444-grw5s2pf	1292	11	represent	represent	VBP
cord-256444-grw5s2pf	1292	12	preferentially	preferentially	RB
cord-256444-grw5s2pf	1292	13	the	the	DT
cord-256444-grw5s2pf	1292	14	3	3	CD
cord-256444-grw5s2pf	1292	15	'	'	NN
cord-256444-grw5s2pf	1292	16	end	end	NN
cord-256444-grw5s2pf	1292	17	sequences	sequence	NNS
cord-256444-grw5s2pf	1292	18	,	,	,
cord-256444-grw5s2pf	1292	19	may	may	MD
cord-256444-grw5s2pf	1292	20	participate	participate	VB
cord-256444-grw5s2pf	1292	21	in	in	IN
cord-256444-grw5s2pf	1292	22	RNA	RNA	NNP
cord-256444-grw5s2pf	1292	23	recombination	recombination	NN
cord-256444-grw5s2pf	1292	24	Baric	Baric	NNP
cord-256444-grw5s2pf	1292	25	,	,	,
cord-256444-grw5s2pf	1292	26	1992	1992	CD
cord-256444-grw5s2pf	1292	27	,	,	,
cord-256444-grw5s2pf	1292	28	1994	1994	CD
cord-256444-grw5s2pf	1292	29	)	)	-RRB-
cord-256444-grw5s2pf	1292	30	.	.	.
cord-256444-grw5s2pf	1293	1	Recombination	recombination	NN
cord-256444-grw5s2pf	1293	2	has	have	VBZ
cord-256444-grw5s2pf	1293	3	now	now	RB
cord-256444-grw5s2pf	1293	4	been	be	VBN
cord-256444-grw5s2pf	1293	5	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	1293	6	experimentally	experimentally	RB
cord-256444-grw5s2pf	1293	7	for	for	IN
cord-256444-grw5s2pf	1293	8	IBV	IBV	NNP
cord-256444-grw5s2pf	1293	9	(	(	-LRB-
cord-256444-grw5s2pf	1293	10	Kotier	Kotier	NNP
cord-256444-grw5s2pf	1293	11	et	et	NNP
cord-256444-grw5s2pf	1293	12	al	al	NNP
cord-256444-grw5s2pf	1293	13	.	.	NNP
cord-256444-grw5s2pf	1293	14	,	,	,
cord-256444-grw5s2pf	1293	15	1995	1995	CD
cord-256444-grw5s2pf	1293	16	)	)	-RRB-
cord-256444-grw5s2pf	1293	17	and	and	CC
cord-256444-grw5s2pf	1293	18	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1293	19	(	(	-LRB-
cord-256444-grw5s2pf	1293	20	Ballesteros	Ballesteros	NNP
cord-256444-grw5s2pf	1293	21	et	et	NNP
cord-256444-grw5s2pf	1293	22	al	al	NNP
cord-256444-grw5s2pf	1293	23	.	.	NNP
cord-256444-grw5s2pf	1293	24	,	,	,
cord-256444-grw5s2pf	1293	25	1997	1997	CD
cord-256444-grw5s2pf	1293	26	)	)	-RRB-
cord-256444-grw5s2pf	1293	27	in	in	IN
cord-256444-grw5s2pf	1293	28	embryonated	embryonate	VBN
cord-256444-grw5s2pf	1293	29	eggs	egg	NNS
cord-256444-grw5s2pf	1293	30	or	or	CC
cord-256444-grw5s2pf	1293	31	tissue	tissue	NN
cord-256444-grw5s2pf	1293	32	culture	culture	NN
cord-256444-grw5s2pf	1293	33	;	;	:
cord-256444-grw5s2pf	1293	34	however	however	RB
cord-256444-grw5s2pf	1293	35	,	,	,
cord-256444-grw5s2pf	1293	36	the	the	DT
cord-256444-grw5s2pf	1293	37	recombination	recombination	NN
cord-256444-grw5s2pf	1293	38	frequency	frequency	NN
cord-256444-grw5s2pf	1293	39	for	for	IN
cord-256444-grw5s2pf	1293	40	these	these	DT
cord-256444-grw5s2pf	1293	41	viruses	virus	NNS
cord-256444-grw5s2pf	1293	42	has	have	VBZ
cord-256444-grw5s2pf	1293	43	not	not	RB
cord-256444-grw5s2pf	1293	44	been	be	VBN
cord-256444-grw5s2pf	1293	45	determined	determine	VBN
cord-256444-grw5s2pf	1293	46	.	.	.
cord-256444-grw5s2pf	1294	1	Recombination	recombination	NN
cord-256444-grw5s2pf	1294	2	can	can	MD
cord-256444-grw5s2pf	1294	3	provide	provide	VB
cord-256444-grw5s2pf	1294	4	a	a	DT
cord-256444-grw5s2pf	1294	5	powerful	powerful	JJ
cord-256444-grw5s2pf	1294	6	tool	tool	NN
cord-256444-grw5s2pf	1294	7	for	for	IN
cord-256444-grw5s2pf	1294	8	virus	virus	NN
cord-256444-grw5s2pf	1294	9	evolution	evolution	NN
cord-256444-grw5s2pf	1294	10	.	.	.
cord-256444-grw5s2pf	1295	1	For	for	IN
cord-256444-grw5s2pf	1295	2	example	example	NN
cord-256444-grw5s2pf	1295	3	,	,	,
cord-256444-grw5s2pf	1295	4	in	in	IN
cord-256444-grw5s2pf	1295	5	a	a	DT
cord-256444-grw5s2pf	1295	6	study	study	NN
cord-256444-grw5s2pf	1295	7	in	in	IN
cord-256444-grw5s2pf	1295	8	which	which	WDT
cord-256444-grw5s2pf	1295	9	ts	ts	NNP
cord-256444-grw5s2pf	1295	10	mutants	mutant	NNS
cord-256444-grw5s2pf	1295	11	of	of	IN
cord-256444-grw5s2pf	1295	12	the	the	DT
cord-256444-grw5s2pf	1295	13	A59	A59	NNP
cord-256444-grw5s2pf	1295	14	strain	strain	NN
cord-256444-grw5s2pf	1295	15	of	of	IN
cord-256444-grw5s2pf	1295	16	MHV	MHV	NNP
cord-256444-grw5s2pf	1295	17	were	be	VBD
cord-256444-grw5s2pf	1295	18	co	co	JJ
cord-256444-grw5s2pf	1295	19	-	-	JJ
cord-256444-grw5s2pf	1295	20	infected	infect	VBN
cord-256444-grw5s2pf	1295	21	with	with	IN
cord-256444-grw5s2pf	1295	22	a	a	DT
cord-256444-grw5s2pf	1295	23	wild	wild	JJ
cord-256444-grw5s2pf	1295	24	-	-	HYPH
cord-256444-grw5s2pf	1295	25	type	type	NN
cord-256444-grw5s2pf	1295	26	JHM	JHM	NNP
cord-256444-grw5s2pf	1295	27	strain	strain	NN
cord-256444-grw5s2pf	1295	28	,	,	,
cord-256444-grw5s2pf	1295	29	the	the	DT
cord-256444-grw5s2pf	1295	30	majority	majority	NN
cord-256444-grw5s2pf	1295	31	of	of	IN
cord-256444-grw5s2pf	1295	32	the	the	DT
cord-256444-grw5s2pf	1295	33	progeny	progeny	NN
cord-256444-grw5s2pf	1295	34	viruses	virus	NNS
cord-256444-grw5s2pf	1295	35	after	after	IN
cord-256444-grw5s2pf	1295	36	a	a	DT
cord-256444-grw5s2pf	1295	37	single	single	JJ
cord-256444-grw5s2pf	1295	38	passage	passage	NN
cord-256444-grw5s2pf	1295	39	were	be	VBD
cord-256444-grw5s2pf	1295	40	recombinants	recombinant	NNS
cord-256444-grw5s2pf	1295	41	which	which	WDT
cord-256444-grw5s2pf	1295	42	contained	contain	VBD
cord-256444-grw5s2pf	1295	43	the	the	DT
cord-256444-grw5s2pf	1295	44	5	5	CD
cord-256444-grw5s2pf	1295	45	'	'	NN
cord-256444-grw5s2pf	1295	46	end	end	NN
cord-256444-grw5s2pf	1295	47	of	of	IN
cord-256444-grw5s2pf	1295	48	the	the	DT
cord-256444-grw5s2pf	1295	49	A59	A59	NNP
cord-256444-grw5s2pf	1295	50	genome	genome	NN
cord-256444-grw5s2pf	1295	51	(	(	-LRB-
cord-256444-grw5s2pf	1295	52	Makino	Makino	NNP
cord-256444-grw5s2pf	1295	53	et	et	NNP
cord-256444-grw5s2pf	1295	54	al	al	NNP
cord-256444-grw5s2pf	1295	55	.	.	NNP
cord-256444-grw5s2pf	1295	56	,	,	,
cord-256444-grw5s2pf	1295	57	1986a	1986a	CD
cord-256444-grw5s2pf	1295	58	)	)	-RRB-
cord-256444-grw5s2pf	1295	59	,	,	,
cord-256444-grw5s2pf	1295	60	suggesting	suggest	VBG
cord-256444-grw5s2pf	1295	61	that	that	IN
cord-256444-grw5s2pf	1295	62	this	this	DT
cord-256444-grw5s2pf	1295	63	recombinant	recombinant	JJ
cord-256444-grw5s2pf	1295	64	virus	virus	NN
cord-256444-grw5s2pf	1295	65	has	have	VBZ
cord-256444-grw5s2pf	1295	66	evolutionary	evolutionary	JJ
cord-256444-grw5s2pf	1295	67	advantages	advantage	NNS
cord-256444-grw5s2pf	1295	68	.	.	.
cord-256444-grw5s2pf	1296	1	Recombination	recombination	NN
cord-256444-grw5s2pf	1296	2	has	have	VBZ
cord-256444-grw5s2pf	1296	3	also	also	RB
cord-256444-grw5s2pf	1296	4	been	be	VBN
cord-256444-grw5s2pf	1296	5	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	1296	6	during	during	IN
cord-256444-grw5s2pf	1296	7	virus	virus	NN
cord-256444-grw5s2pf	1296	8	infection	infection	NN
cord-256444-grw5s2pf	1296	9	in	in	IN
cord-256444-grw5s2pf	1296	10	animals	animal	NNS
cord-256444-grw5s2pf	1296	11	(	(	-LRB-
cord-256444-grw5s2pf	1296	12	Keck	Keck	NNP
cord-256444-grw5s2pf	1296	13	et	et	NNP
cord-256444-grw5s2pf	1296	14	al	al	NNP
cord-256444-grw5s2pf	1296	15	.	.	NNP
cord-256444-grw5s2pf	1296	16	,	,	,
cord-256444-grw5s2pf	1296	17	198813	198813	CD
cord-256444-grw5s2pf	1296	18	)	)	-RRB-
cord-256444-grw5s2pf	1296	19	.	.	.
cord-256444-grw5s2pf	1297	1	Similar	similar	JJ
cord-256444-grw5s2pf	1297	2	to	to	IN
cord-256444-grw5s2pf	1297	3	the	the	DT
cord-256444-grw5s2pf	1297	4	situation	situation	NN
cord-256444-grw5s2pf	1297	5	in	in	IN
cord-256444-grw5s2pf	1297	6	other	other	JJ
cord-256444-grw5s2pf	1297	7	RNA	RNA	NNP
cord-256444-grw5s2pf	1297	8	viruses	virus	NNS
cord-256444-grw5s2pf	1297	9	,	,	,
cord-256444-grw5s2pf	1297	10	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1297	11	recombination	recombination	NN
cord-256444-grw5s2pf	1297	12	probably	probably	RB
cord-256444-grw5s2pf	1297	13	occurs	occur	VBZ
cord-256444-grw5s2pf	1297	14	by	by	IN
cord-256444-grw5s2pf	1297	15	a	a	DT
cord-256444-grw5s2pf	1297	16	copy	copy	NN
cord-256444-grw5s2pf	1297	17	-	-	HYPH
cord-256444-grw5s2pf	1297	18	choice	choice	NN
cord-256444-grw5s2pf	1297	19	mechanism	mechanism	NN
cord-256444-grw5s2pf	1297	20	(	(	-LRB-
cord-256444-grw5s2pf	1297	21	Lai	Lai	NNP
cord-256444-grw5s2pf	1297	22	,	,	,
cord-256444-grw5s2pf	1297	23	1992	1992	CD
cord-256444-grw5s2pf	1297	24	)	)	-RRB-
cord-256444-grw5s2pf	1297	25	.	.	.
cord-256444-grw5s2pf	1298	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1298	2	has	have	VBZ
cord-256444-grw5s2pf	1298	3	been	be	VBN
cord-256444-grw5s2pf	1298	4	shown	show	VBN
cord-256444-grw5s2pf	1298	5	that	that	IN
cord-256444-grw5s2pf	1298	6	MHV	MHV	NNP
cord-256444-grw5s2pf	1298	7	RNA	RNA	NNP
cord-256444-grw5s2pf	1298	8	synthesis	synthesis	NN
cord-256444-grw5s2pf	1298	9	normally	normally	RB
cord-256444-grw5s2pf	1298	10	pauses	pause	VBZ
cord-256444-grw5s2pf	1298	11	at	at	IN
cord-256444-grw5s2pf	1298	12	certain	certain	JJ
cord-256444-grw5s2pf	1298	13	sites	site	NNS
cord-256444-grw5s2pf	1298	14	on	on	IN
cord-256444-grw5s2pf	1298	15	the	the	DT
cord-256444-grw5s2pf	1298	16	RNA	RNA	NNP
cord-256444-grw5s2pf	1298	17	genome	genome	NN
cord-256444-grw5s2pf	1299	1	(	(	-LRB-
cord-256444-grw5s2pf	1299	2	Baric	Baric	NNP
cord-256444-grw5s2pf	1299	3	et	et	NNP
cord-256444-grw5s2pf	1299	4	al	al	NNP
cord-256444-grw5s2pf	1299	5	.	.	NNP
cord-256444-grw5s2pf	1299	6	,	,	,
cord-256444-grw5s2pf	1299	7	1987	1987	CD
cord-256444-grw5s2pf	1299	8	)	)	-RRB-
cord-256444-grw5s2pf	1299	9	.	.	.
cord-256444-grw5s2pf	1300	1	The	the	DT
cord-256444-grw5s2pf	1300	2	nascent	nascent	JJ
cord-256444-grw5s2pf	1300	3	,	,	,
cord-256444-grw5s2pf	1300	4	incomplete	incomplete	JJ
cord-256444-grw5s2pf	1300	5	RNA	RNA	NNP
cord-256444-grw5s2pf	1300	6	transcripts	transcript	NNS
cord-256444-grw5s2pf	1300	7	may	may	MD
cord-256444-grw5s2pf	1300	8	dissociate	dissociate	VB
cord-256444-grw5s2pf	1300	9	from	from	IN
cord-256444-grw5s2pf	1300	10	the	the	DT
cord-256444-grw5s2pf	1300	11	template	template	NN
cord-256444-grw5s2pf	1300	12	RNA	RNA	NNP
cord-256444-grw5s2pf	1300	13	and	and	CC
cord-256444-grw5s2pf	1300	14	then	then	RB
cord-256444-grw5s2pf	1300	15	rebind	rebind	VB
cord-256444-grw5s2pf	1300	16	to	to	IN
cord-256444-grw5s2pf	1300	17	the	the	DT
cord-256444-grw5s2pf	1300	18	template	template	NN
cord-256444-grw5s2pf	1300	19	to	to	TO
cord-256444-grw5s2pf	1300	20	resume	resume	VB
cord-256444-grw5s2pf	1300	21	RNA	RNA	NNP
cord-256444-grw5s2pf	1300	22	synthesis	synthesis	NN
cord-256444-grw5s2pf	1300	23	.	.	.
cord-256444-grw5s2pf	1301	1	When	when	WRB
cord-256444-grw5s2pf	1301	2	the	the	DT
cord-256444-grw5s2pf	1301	3	nascent	nascent	JJ
cord-256444-grw5s2pf	1301	4	RNA	RNA	NNP
cord-256444-grw5s2pf	1301	5	binds	bind	VBZ
cord-256444-grw5s2pf	1301	6	to	to	IN
cord-256444-grw5s2pf	1301	7	a	a	DT
cord-256444-grw5s2pf	1301	8	different	different	JJ
cord-256444-grw5s2pf	1301	9	template	template	NN
cord-256444-grw5s2pf	1301	10	,	,	,
cord-256444-grw5s2pf	1301	11	the	the	DT
cord-256444-grw5s2pf	1301	12	resumed	resume	VBN
cord-256444-grw5s2pf	1301	13	RNA	RNA	NNP
cord-256444-grw5s2pf	1301	14	synthesis	synthesis	NN
cord-256444-grw5s2pf	1301	15	will	will	MD
cord-256444-grw5s2pf	1301	16	result	result	VB
cord-256444-grw5s2pf	1301	17	in	in	IN
cord-256444-grw5s2pf	1301	18	a	a	DT
cord-256444-grw5s2pf	1301	19	recombinant	recombinant	JJ
cord-256444-grw5s2pf	1301	20	RNA	rna	NN
cord-256444-grw5s2pf	1301	21	.	.	.
cord-256444-grw5s2pf	1302	1	Whether	whether	IN
cord-256444-grw5s2pf	1302	2	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1302	3	recombination	recombination	NN
cord-256444-grw5s2pf	1302	4	occurs	occur	VBZ
cord-256444-grw5s2pf	1302	5	more	more	RBR
cord-256444-grw5s2pf	1302	6	frequently	frequently	RB
cord-256444-grw5s2pf	1302	7	at	at	IN
cord-256444-grw5s2pf	1302	8	certain	certain	JJ
cord-256444-grw5s2pf	1302	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1302	10	sites	site	NNS
cord-256444-grw5s2pf	1302	11	with	with	IN
cord-256444-grw5s2pf	1302	12	more	more	RBR
cord-256444-grw5s2pf	1302	13	complex	complex	JJ
cord-256444-grw5s2pf	1302	14	secondary	secondary	JJ
cord-256444-grw5s2pf	1302	15	structure	structure	NN
cord-256444-grw5s2pf	1302	16	is	be	VBZ
cord-256444-grw5s2pf	1302	17	not	not	RB
cord-256444-grw5s2pf	1302	18	yet	yet	RB
cord-256444-grw5s2pf	1302	19	known	know	VBN
cord-256444-grw5s2pf	1302	20	.	.	.
cord-256444-grw5s2pf	1303	1	When	when	WRB
cord-256444-grw5s2pf	1303	2	RNA	RNA	NNP
cord-256444-grw5s2pf	1303	3	recombination	recombination	NN
cord-256444-grw5s2pf	1303	4	was	be	VBD
cord-256444-grw5s2pf	1303	5	examined	examine	VBN
cord-256444-grw5s2pf	1303	6	under	under	IN
cord-256444-grw5s2pf	1303	7	nonselective	nonselective	JJ
cord-256444-grw5s2pf	1303	8	conditions	condition	NNS
cord-256444-grw5s2pf	1303	9	(	(	-LRB-
cord-256444-grw5s2pf	1303	10	by	by	IN
cord-256444-grw5s2pf	1303	11	reverse	reverse	JJ
cord-256444-grw5s2pf	1303	12	transcription	transcription	NN
cord-256444-grw5s2pf	1303	13	-	-	HYPH
cord-256444-grw5s2pf	1303	14	polymerase	polymerase	NN
cord-256444-grw5s2pf	1303	15	chain	chain	NN
cord-256444-grw5s2pf	1303	16	reaction	reaction	NN
cord-256444-grw5s2pf	1303	17	detection	detection	NN
cord-256444-grw5s2pf	1303	18	of	of	IN
cord-256444-grw5s2pf	1303	19	the	the	DT
cord-256444-grw5s2pf	1303	20	intracellular	intracellular	JJ
cord-256444-grw5s2pf	1303	21	RNA	RNA	NNP
cord-256444-grw5s2pf	1303	22	from	from	IN
cord-256444-grw5s2pf	1303	23	virus	virus	NN
cord-256444-grw5s2pf	1303	24	-	-	HYPH
cord-256444-grw5s2pf	1303	25	infected	infect	VBN
cord-256444-grw5s2pf	1303	26	cells	cell	NNS
cord-256444-grw5s2pf	1303	27	)	)	-RRB-
cord-256444-grw5s2pf	1303	28	,	,	,
cord-256444-grw5s2pf	1303	29	recombination	recombination	NN
cord-256444-grw5s2pf	1303	30	sites	site	NNS
cord-256444-grw5s2pf	1303	31	appeared	appear	VBD
cord-256444-grw5s2pf	1303	32	to	to	TO
cord-256444-grw5s2pf	1303	33	be	be	VB
cord-256444-grw5s2pf	1303	34	random	random	JJ
cord-256444-grw5s2pf	1303	35	;	;	:
cord-256444-grw5s2pf	1303	36	only	only	RB
cord-256444-grw5s2pf	1303	37	after	after	IN
cord-256444-grw5s2pf	1303	38	serial	serial	JJ
cord-256444-grw5s2pf	1303	39	passages	passage	NNS
cord-256444-grw5s2pf	1303	40	did	do	VBD
cord-256444-grw5s2pf	1303	41	"	"	``
cord-256444-grw5s2pf	1303	42	hot	hot	JJ
cord-256444-grw5s2pf	1303	43	spots	spot	NNS
cord-256444-grw5s2pf	1303	44	"	"	''
cord-256444-grw5s2pf	1303	45	of	of	IN
cord-256444-grw5s2pf	1303	46	RNA	RNA	NNP
cord-256444-grw5s2pf	1303	47	recombination	recombination	NN
cord-256444-grw5s2pf	1303	48	become	become	VBP
cord-256444-grw5s2pf	1303	49	apparent	apparent	JJ
cord-256444-grw5s2pf	1303	50	.	.	.
cord-256444-grw5s2pf	1304	1	This	this	DT
cord-256444-grw5s2pf	1304	2	finding	finding	NN
cord-256444-grw5s2pf	1304	3	indicates	indicate	VBZ
cord-256444-grw5s2pf	1304	4	that	that	IN
cord-256444-grw5s2pf	1304	5	the	the	DT
cord-256444-grw5s2pf	1304	6	recombination	recombination	NN
cord-256444-grw5s2pf	1304	7	hot	hot	JJ
cord-256444-grw5s2pf	1304	8	spots	spot	NNS
cord-256444-grw5s2pf	1304	9	may	may	MD
cord-256444-grw5s2pf	1304	10	be	be	VB
cord-256444-grw5s2pf	1304	11	the	the	DT
cord-256444-grw5s2pf	1304	12	result	result	NN
cord-256444-grw5s2pf	1304	13	of	of	IN
cord-256444-grw5s2pf	1304	14	selection	selection	NN
cord-256444-grw5s2pf	1304	15	.	.	.
cord-256444-grw5s2pf	1305	1	Recombination	recombination	NN
cord-256444-grw5s2pf	1305	2	has	have	VBZ
cord-256444-grw5s2pf	1305	3	been	be	VBN
cord-256444-grw5s2pf	1305	4	detected	detect	VBN
cord-256444-grw5s2pf	1305	5	during	during	IN
cord-256444-grw5s2pf	1305	6	natural	natural	JJ
cord-256444-grw5s2pf	1305	7	infections	infection	NNS
cord-256444-grw5s2pf	1305	8	of	of	IN
cord-256444-grw5s2pf	1305	9	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1305	10	,	,	,
cord-256444-grw5s2pf	1305	11	most	most	RBS
cord-256444-grw5s2pf	1305	12	notably	notably	RB
cord-256444-grw5s2pf	1305	13	IBV	IBV	NNP
cord-256444-grw5s2pf	1305	14	.	.	.
cord-256444-grw5s2pf	1306	1	Sequence	sequence	NN
cord-256444-grw5s2pf	1306	2	analysis	analysis	NN
cord-256444-grw5s2pf	1306	3	of	of	IN
cord-256444-grw5s2pf	1306	4	natural	natural	JJ
cord-256444-grw5s2pf	1306	5	IBV	IBV	NNP
cord-256444-grw5s2pf	1306	6	strains	strain	NNS
cord-256444-grw5s2pf	1306	7	has	have	VBZ
cord-256444-grw5s2pf	1306	8	provided	provide	VBN
cord-256444-grw5s2pf	1306	9	convincing	convincing	JJ
cord-256444-grw5s2pf	1306	10	evidence	evidence	NN
cord-256444-grw5s2pf	1306	11	that	that	IN
cord-256444-grw5s2pf	1306	12	some	some	DT
cord-256444-grw5s2pf	1306	13	IBV	IBV	NNP
cord-256444-grw5s2pf	1306	14	strains	strain	NNS
cord-256444-grw5s2pf	1306	15	are	be	VBP
cord-256444-grw5s2pf	1306	16	recombinants	recombinant	NNS
cord-256444-grw5s2pf	1306	17	between	between	IN
cord-256444-grw5s2pf	1306	18	different	different	JJ
cord-256444-grw5s2pf	1306	19	IBV	IBV	NNP
cord-256444-grw5s2pf	1306	20	strains	strain	NNS
cord-256444-grw5s2pf	1306	21	;	;	:
cord-256444-grw5s2pf	1306	22	recombination	recombination	NN
cord-256444-grw5s2pf	1306	23	sites	site	NNS
cord-256444-grw5s2pf	1306	24	have	have	VBP
cord-256444-grw5s2pf	1306	25	been	be	VBN
cord-256444-grw5s2pf	1306	26	detected	detect	VBN
cord-256444-grw5s2pf	1306	27	so	so	RB
cord-256444-grw5s2pf	1306	28	far	far	RB
cord-256444-grw5s2pf	1306	29	in	in	IN
cord-256444-grw5s2pf	1306	30	the	the	DT
cord-256444-grw5s2pf	1306	31	5	5	CD
cord-256444-grw5s2pf	1306	32	'	'	CD
cord-256444-grw5s2pf	1306	33	half	half	NN
cord-256444-grw5s2pf	1306	34	of	of	IN
cord-256444-grw5s2pf	1306	35	the	the	DT
cord-256444-grw5s2pf	1306	36	S	S	NNP
cord-256444-grw5s2pf	1306	37	gene	gene	NN
cord-256444-grw5s2pf	1306	38	and	and	CC
cord-256444-grw5s2pf	1306	39	at	at	IN
cord-256444-grw5s2pf	1306	40	the	the	DT
cord-256444-grw5s2pf	1306	41	3	3	CD
cord-256444-grw5s2pf	1306	42	'	'	NN
cord-256444-grw5s2pf	1306	43	end	end	NN
cord-256444-grw5s2pf	1306	44	of	of	IN
cord-256444-grw5s2pf	1306	45	viral	viral	JJ
cord-256444-grw5s2pf	1306	46	RNA	RNA	NNP
cord-256444-grw5s2pf	1306	47	(	(	-LRB-
cord-256444-grw5s2pf	1306	48	Kusters	Kusters	NNPS
cord-256444-grw5s2pf	1306	49	et	et	NNP
cord-256444-grw5s2pf	1306	50	al	al	NNP
cord-256444-grw5s2pf	1306	51	.	.	NNP
cord-256444-grw5s2pf	1306	52	,	,	,
cord-256444-grw5s2pf	1306	53	1989	1989	CD
cord-256444-grw5s2pf	1306	54	;	;	:
cord-256444-grw5s2pf	1306	55	Cavanagh	Cavanagh	NNP
cord-256444-grw5s2pf	1306	56	and	and	CC
cord-256444-grw5s2pf	1306	57	Davis	Davis	NNP
cord-256444-grw5s2pf	1306	58	,	,	,
cord-256444-grw5s2pf	1306	59	1992	1992	CD
cord-256444-grw5s2pf	1306	60	;	;	:
cord-256444-grw5s2pf	1306	61	Wang	Wang	NNP
cord-256444-grw5s2pf	1306	62	et	et	NNP
cord-256444-grw5s2pf	1306	63	al	al	NNP
cord-256444-grw5s2pf	1306	64	.	.	NNP
cord-256444-grw5s2pf	1306	65	,	,	,
cord-256444-grw5s2pf	1306	66	1993	1993	CD
cord-256444-grw5s2pf	1307	1	Wang	Wang	NNP
cord-256444-grw5s2pf	1307	2	et	et	NNP
cord-256444-grw5s2pf	1307	3	al	al	NNP
cord-256444-grw5s2pf	1307	4	.	.	.
cord-256444-grw5s2pf	1308	1	,	,	,
cord-256444-grw5s2pf	1308	2	,	,	,
cord-256444-grw5s2pf	1308	3	1994	1994	CD
cord-256444-grw5s2pf	1308	4	Jia	Jia	NNP
cord-256444-grw5s2pf	1308	5	et	et	NNP
cord-256444-grw5s2pf	1308	6	al	al	NNP
cord-256444-grw5s2pf	1308	7	.	.	NNP
cord-256444-grw5s2pf	1308	8	,	,	,
cord-256444-grw5s2pf	1308	9	1995	1995	CD
cord-256444-grw5s2pf	1308	10	)	)	-RRB-
cord-256444-grw5s2pf	1308	11	.	.	.
cord-256444-grw5s2pf	1309	1	Thus	thus	RB
cord-256444-grw5s2pf	1309	2	,	,	,
cord-256444-grw5s2pf	1309	3	recombination	recombination	NN
cord-256444-grw5s2pf	1309	4	is	be	VBZ
cord-256444-grw5s2pf	1309	5	a	a	DT
cord-256444-grw5s2pf	1309	6	natural	natural	JJ
cord-256444-grw5s2pf	1309	7	evolutionary	evolutionary	JJ
cord-256444-grw5s2pf	1309	8	strategy	strategy	NN
cord-256444-grw5s2pf	1309	9	for	for	IN
cord-256444-grw5s2pf	1309	10	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1309	11	.	.	.
cord-256444-grw5s2pf	1310	1	RNA	RNA	NNP
cord-256444-grw5s2pf	1310	2	recombination	recombination	NN
cord-256444-grw5s2pf	1310	3	may	may	MD
cord-256444-grw5s2pf	1310	4	also	also	RB
cord-256444-grw5s2pf	1310	5	explain	explain	VB
cord-256444-grw5s2pf	1310	6	the	the	DT
cord-256444-grw5s2pf	1310	7	difference	difference	NN
cord-256444-grw5s2pf	1310	8	in	in	IN
cord-256444-grw5s2pf	1310	9	genome	genome	NN
cord-256444-grw5s2pf	1310	10	structure	structure	NN
cord-256444-grw5s2pf	1310	11	among	among	IN
cord-256444-grw5s2pf	1310	12	different	different	JJ
cord-256444-grw5s2pf	1310	13	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1310	14	.	.	.
cord-256444-grw5s2pf	1311	1	For	for	IN
cord-256444-grw5s2pf	1311	2	example	example	NN
cord-256444-grw5s2pf	1311	3	,	,	,
cord-256444-grw5s2pf	1311	4	IBV	IBV	NNP
cord-256444-grw5s2pf	1311	5	contains	contain	VBZ
cord-256444-grw5s2pf	1311	6	an	an	DT
cord-256444-grw5s2pf	1311	7	additional	additional	JJ
cord-256444-grw5s2pf	1311	8	gene	gene	NN
cord-256444-grw5s2pf	1311	9	,	,	,
cord-256444-grw5s2pf	1311	10	gene	gene	NN
cord-256444-grw5s2pf	1311	11	5	5	CD
cord-256444-grw5s2pf	1311	12	(	(	-LRB-
cord-256444-grw5s2pf	1311	13	a	a	DT
cord-256444-grw5s2pf	1311	14	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	1311	15	protein	protein	NN
cord-256444-grw5s2pf	1311	16	gene	gene	NN
cord-256444-grw5s2pf	1311	17	)	)	-RRB-
cord-256444-grw5s2pf	1311	18	inserted	insert	VBN
cord-256444-grw5s2pf	1311	19	between	between	IN
cord-256444-grw5s2pf	1311	20	gene	gene	NN
cord-256444-grw5s2pf	1311	21	M	M	NNP
cord-256444-grw5s2pf	1311	22	and	and	CC
cord-256444-grw5s2pf	1311	23	gene	gene	NN
cord-256444-grw5s2pf	1311	24	N	n	CD
cord-256444-grw5s2pf	1311	25	(	(	-LRB-
cord-256444-grw5s2pf	1311	26	Fig	Fig	NNP
cord-256444-grw5s2pf	1311	27	.	.	NNP
cord-256444-grw5s2pf	1311	28	5	5	CD
cord-256444-grw5s2pf	1311	29	)	)	-RRB-
cord-256444-grw5s2pf	1311	30	.	.	.
cord-256444-grw5s2pf	1312	1	This	this	DT
cord-256444-grw5s2pf	1312	2	insertion	insertion	NN
cord-256444-grw5s2pf	1312	3	could	could	MD
cord-256444-grw5s2pf	1312	4	be	be	VB
cord-256444-grw5s2pf	1312	5	the	the	DT
cord-256444-grw5s2pf	1312	6	result	result	NN
cord-256444-grw5s2pf	1312	7	of	of	IN
cord-256444-grw5s2pf	1312	8	a	a	DT
cord-256444-grw5s2pf	1312	9	recombination	recombination	NN
cord-256444-grw5s2pf	1312	10	mechanism	mechanism	NN
cord-256444-grw5s2pf	1312	11	involving	involve	VBG
cord-256444-grw5s2pf	1312	12	the	the	DT
cord-256444-grw5s2pf	1312	13	consensus	consensus	NN
cord-256444-grw5s2pf	1312	14	IG	ig	NN
cord-256444-grw5s2pf	1312	15	sequence	sequence	NN
cord-256444-grw5s2pf	1312	16	,	,	,
cord-256444-grw5s2pf	1312	17	which	which	WDT
cord-256444-grw5s2pf	1312	18	provides	provide	VBZ
cord-256444-grw5s2pf	1312	19	a	a	DT
cord-256444-grw5s2pf	1312	20	favored	favor	VBN
cord-256444-grw5s2pf	1312	21	recombination	recombination	NN
cord-256444-grw5s2pf	1312	22	site	site	NN
cord-256444-grw5s2pf	1312	23	.	.	.
cord-256444-grw5s2pf	1313	1	Since	since	IN
cord-256444-grw5s2pf	1313	2	all	all	DT
cord-256444-grw5s2pf	1313	3	of	of	IN
cord-256444-grw5s2pf	1313	4	the	the	DT
cord-256444-grw5s2pf	1313	5	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1313	6	genes	gene	NNS
cord-256444-grw5s2pf	1313	7	are	be	VBP
cord-256444-grw5s2pf	1313	8	flanked	flank	VBN
cord-256444-grw5s2pf	1313	9	by	by	IN
cord-256444-grw5s2pf	1313	10	consensus	consensus	NN
cord-256444-grw5s2pf	1313	11	IG	ig	NN
cord-256444-grw5s2pf	1313	12	sequences	sequence	NNS
cord-256444-grw5s2pf	1313	13	,	,	,
cord-256444-grw5s2pf	1313	14	each	each	DT
cord-256444-grw5s2pf	1313	15	gene	gene	NN
cord-256444-grw5s2pf	1313	16	can	can	MD
cord-256444-grw5s2pf	1313	17	be	be	VB
cord-256444-grw5s2pf	1313	18	considered	consider	VBN
cord-256444-grw5s2pf	1313	19	a	a	DT
cord-256444-grw5s2pf	1313	20	gene	gene	NN
cord-256444-grw5s2pf	1313	21	"	"	``
cord-256444-grw5s2pf	1313	22	cassette	cassette	NN
cord-256444-grw5s2pf	1313	23	,	,	,
cord-256444-grw5s2pf	1313	24	"	"	''
cord-256444-grw5s2pf	1313	25	which	which	WDT
cord-256444-grw5s2pf	1313	26	can	can	MD
cord-256444-grw5s2pf	1313	27	be	be	VB
cord-256444-grw5s2pf	1313	28	rearranged	rearrange	VBN
cord-256444-grw5s2pf	1313	29	by	by	IN
cord-256444-grw5s2pf	1313	30	homologous	homologous	JJ
cord-256444-grw5s2pf	1313	31	recombination	recombination	NN
cord-256444-grw5s2pf	1313	32	involving	involve	VBG
cord-256444-grw5s2pf	1313	33	the	the	DT
cord-256444-grw5s2pf	1313	34	consensus	consensus	NN
cord-256444-grw5s2pf	1313	35	IG	ig	NN
cord-256444-grw5s2pf	1313	36	sequence	sequence	NN
cord-256444-grw5s2pf	1313	37	.	.	.
cord-256444-grw5s2pf	1314	1	A	a	DT
cord-256444-grw5s2pf	1314	2	nonhomologous	nonhomologous	JJ
cord-256444-grw5s2pf	1314	3	recombination	recombination	NN
cord-256444-grw5s2pf	1314	4	event	event	NN
cord-256444-grw5s2pf	1314	5	between	between	IN
cord-256444-grw5s2pf	1314	6	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1314	7	RNAs	rna	NNS
cord-256444-grw5s2pf	1314	8	and	and	CC
cord-256444-grw5s2pf	1314	9	other	other	JJ
cord-256444-grw5s2pf	1314	10	virus	virus	NN
cord-256444-grw5s2pf	1314	11	or	or	CC
cord-256444-grw5s2pf	1314	12	cellular	cellular	JJ
cord-256444-grw5s2pf	1314	13	RNAs	rna	NNS
cord-256444-grw5s2pf	1314	14	may	may	MD
cord-256444-grw5s2pf	1314	15	also	also	RB
cord-256444-grw5s2pf	1314	16	explain	explain	VB
cord-256444-grw5s2pf	1314	17	the	the	DT
cord-256444-grw5s2pf	1314	18	gene	gene	NN
cord-256444-grw5s2pf	1314	19	insertions	insertion	NNS
cord-256444-grw5s2pf	1314	20	in	in	IN
cord-256444-grw5s2pf	1314	21	some	some	DT
cord-256444-grw5s2pf	1314	22	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1314	23	.	.	.
cord-256444-grw5s2pf	1315	1	For	for	IN
cord-256444-grw5s2pf	1315	2	example	example	NN
cord-256444-grw5s2pf	1315	3	,	,	,
cord-256444-grw5s2pf	1315	4	MHV	MHV	NNP
cord-256444-grw5s2pf	1315	5	and	and	CC
cord-256444-grw5s2pf	1315	6	BCV	BCV	NNP
cord-256444-grw5s2pf	1315	7	contain	contain	VBP
cord-256444-grw5s2pf	1315	8	an	an	DT
cord-256444-grw5s2pf	1315	9	additional	additional	JJ
cord-256444-grw5s2pf	1315	10	gene	gene	NN
cord-256444-grw5s2pf	1315	11	,	,	,
cord-256444-grw5s2pf	1315	12	HE	HE	NNP
cord-256444-grw5s2pf	1315	13	,	,	,
cord-256444-grw5s2pf	1315	14	which	which	WDT
cord-256444-grw5s2pf	1315	15	is	be	VBZ
cord-256444-grw5s2pf	1315	16	similar	similar	JJ
cord-256444-grw5s2pf	1315	17	in	in	IN
cord-256444-grw5s2pf	1315	18	sequence	sequence	NN
cord-256444-grw5s2pf	1315	19	to	to	IN
cord-256444-grw5s2pf	1315	20	the	the	DT
cord-256444-grw5s2pf	1315	21	HE	HE	NNP
cord-256444-grw5s2pf	1315	22	gene	gene	NN
cord-256444-grw5s2pf	1315	23	of	of	IN
cord-256444-grw5s2pf	1315	24	influenza	influenza	NN
cord-256444-grw5s2pf	1315	25	C	c	NN
cord-256444-grw5s2pf	1315	26	virus	virus	NN
cord-256444-grw5s2pf	1315	27	(	(	-LRB-
cord-256444-grw5s2pf	1315	28	Luytjes	Luytjes	NNP
cord-256444-grw5s2pf	1315	29	et	et	NNP
cord-256444-grw5s2pf	1315	30	al	al	NNP
cord-256444-grw5s2pf	1315	31	.	.	NNP
cord-256444-grw5s2pf	1315	32	,	,	,
cord-256444-grw5s2pf	1315	33	1988	1988	CD
cord-256444-grw5s2pf	1315	34	)	)	-RRB-
cord-256444-grw5s2pf	1315	35	.	.	.
cord-256444-grw5s2pf	1316	1	This	this	DT
cord-256444-grw5s2pf	1316	2	gene	gene	NN
cord-256444-grw5s2pf	1316	3	may	may	MD
cord-256444-grw5s2pf	1316	4	have	have	VB
cord-256444-grw5s2pf	1316	5	been	be	VBN
cord-256444-grw5s2pf	1316	6	derived	derive	VBN
cord-256444-grw5s2pf	1316	7	by	by	IN
cord-256444-grw5s2pf	1316	8	recombination	recombination	NN
cord-256444-grw5s2pf	1316	9	between	between	IN
cord-256444-grw5s2pf	1316	10	a	a	DT
cord-256444-grw5s2pf	1316	11	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1316	12	and	and	CC
cord-256444-grw5s2pf	1316	13	influenza	influenza	NN
cord-256444-grw5s2pf	1316	14	C	c	NN
cord-256444-grw5s2pf	1316	15	virus	virus	NN
cord-256444-grw5s2pf	1316	16	.	.	.
cord-256444-grw5s2pf	1317	1	Comparison	comparison	NN
cord-256444-grw5s2pf	1317	2	between	between	IN
cord-256444-grw5s2pf	1317	3	genome	genome	NN
cord-256444-grw5s2pf	1317	4	structures	structure	NNS
cord-256444-grw5s2pf	1317	5	of	of	IN
cord-256444-grw5s2pf	1317	6	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1317	7	and	and	CC
cord-256444-grw5s2pf	1317	8	torovirus	torovirus	NNP
cord-256444-grw5s2pf	1317	9	also	also	RB
cord-256444-grw5s2pf	1317	10	suggests	suggest	VBZ
cord-256444-grw5s2pf	1317	11	that	that	IN
cord-256444-grw5s2pf	1317	12	several	several	JJ
cord-256444-grw5s2pf	1317	13	recombination	recombination	NN
cord-256444-grw5s2pf	1317	14	events	event	NNS
cord-256444-grw5s2pf	1317	15	may	may	MD
cord-256444-grw5s2pf	1317	16	have	have	VB
cord-256444-grw5s2pf	1317	17	been	be	VBN
cord-256444-grw5s2pf	1317	18	involved	involve	VBN
cord-256444-grw5s2pf	1317	19	in	in	IN
cord-256444-grw5s2pf	1317	20	rearranging	rearrange	VBG
cord-256444-grw5s2pf	1317	21	the	the	DT
cord-256444-grw5s2pf	1317	22	order	order	NN
cord-256444-grw5s2pf	1317	23	of	of	IN
cord-256444-grw5s2pf	1317	24	several	several	JJ
cord-256444-grw5s2pf	1317	25	genes	gene	NNS
cord-256444-grw5s2pf	1317	26	during	during	IN
cord-256444-grw5s2pf	1317	27	the	the	DT
cord-256444-grw5s2pf	1317	28	evolution	evolution	NN
cord-256444-grw5s2pf	1317	29	of	of	IN
cord-256444-grw5s2pf	1317	30	these	these	DT
cord-256444-grw5s2pf	1317	31	viruses	virus	NNS
cord-256444-grw5s2pf	1317	32	(	(	-LRB-
cord-256444-grw5s2pf	1317	33	Snijder	Snijder	NNP
cord-256444-grw5s2pf	1317	34	et	et	NNP
cord-256444-grw5s2pf	1317	35	al	al	NNP
cord-256444-grw5s2pf	1317	36	.	.	NNP
cord-256444-grw5s2pf	1317	37	,	,	,
cord-256444-grw5s2pf	1317	38	1991	1991	CD
cord-256444-grw5s2pf	1317	39	)	)	-RRB-
cord-256444-grw5s2pf	1317	40	.	.	.
cord-256444-grw5s2pf	1318	1	Recombination	recombination	NN
cord-256444-grw5s2pf	1318	2	has	have	VBZ
cord-256444-grw5s2pf	1318	3	been	be	VBN
cord-256444-grw5s2pf	1318	4	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	1318	5	to	to	TO
cord-256444-grw5s2pf	1318	6	occur	occur	VB
cord-256444-grw5s2pf	1318	7	between	between	IN
cord-256444-grw5s2pf	1318	8	viral	viral	JJ
cord-256444-grw5s2pf	1318	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1318	10	and	and	CC
cord-256444-grw5s2pf	1318	11	a	a	DT
cord-256444-grw5s2pf	1318	12	transfected	transfecte	VBN
cord-256444-grw5s2pf	1318	13	RNA	rna	NN
cord-256444-grw5s2pf	1318	14	fragment	fragment	NN
cord-256444-grw5s2pf	1318	15	derived	derive	VBN
cord-256444-grw5s2pf	1318	16	from	from	IN
cord-256444-grw5s2pf	1318	17	the	the	DT
cord-256444-grw5s2pf	1318	18	viral	viral	JJ
cord-256444-grw5s2pf	1318	19	genome	genome	NN
cord-256444-grw5s2pf	1318	20	(	(	-LRB-
cord-256444-grw5s2pf	1318	21	Koetzner	Koetzner	NNP
cord-256444-grw5s2pf	1318	22	et	et	NNP
cord-256444-grw5s2pf	1318	23	al	al	NNP
cord-256444-grw5s2pf	1318	24	.	.	NNP
cord-256444-grw5s2pf	1318	25	,	,	,
cord-256444-grw5s2pf	1318	26	1992	1992	CD
cord-256444-grw5s2pf	1318	27	;	;	.
cord-256444-grw5s2pf	1319	1	Liao	Liao	NNP
cord-256444-grw5s2pf	1319	2	and	and	CC
cord-256444-grw5s2pf	1319	3	Lai	Lai	NNP
cord-256444-grw5s2pf	1319	4	,	,	,
cord-256444-grw5s2pf	1319	5	1992	1992	CD
cord-256444-grw5s2pf	1319	6	)	)	-RRB-
cord-256444-grw5s2pf	1319	7	.	.	.
cord-256444-grw5s2pf	1320	1	Since	since	IN
cord-256444-grw5s2pf	1320	2	transfection	transfection	NN
cord-256444-grw5s2pf	1320	3	of	of	IN
cord-256444-grw5s2pf	1320	4	both	both	CC
cord-256444-grw5s2pf	1320	5	the	the	DT
cord-256444-grw5s2pf	1320	6	positive	positive	JJ
cord-256444-grw5s2pf	1320	7	-	-	HYPH
cord-256444-grw5s2pf	1320	8	and	and	CC
cord-256444-grw5s2pf	1320	9	negative	negative	JJ
cord-256444-grw5s2pf	1320	10	-	-	HYPH
cord-256444-grw5s2pf	1320	11	strand	strand	NN
cord-256444-grw5s2pf	1320	12	RNA	rna	NN
cord-256444-grw5s2pf	1320	13	fragments	fragment	NNS
cord-256444-grw5s2pf	1320	14	led	lead	VBD
cord-256444-grw5s2pf	1320	15	to	to	IN
cord-256444-grw5s2pf	1320	16	recombination	recombination	NN
cord-256444-grw5s2pf	1320	17	,	,	,
cord-256444-grw5s2pf	1320	18	these	these	DT
cord-256444-grw5s2pf	1320	19	results	result	NNS
cord-256444-grw5s2pf	1320	20	suggested	suggest	VBD
cord-256444-grw5s2pf	1320	21	that	that	IN
cord-256444-grw5s2pf	1320	22	recombination	recombination	NN
cord-256444-grw5s2pf	1320	23	can	can	MD
cord-256444-grw5s2pf	1320	24	occur	occur	VB
cord-256444-grw5s2pf	1320	25	during	during	IN
cord-256444-grw5s2pf	1320	26	both	both	DT
cord-256444-grw5s2pf	1320	27	positive	positive	JJ
cord-256444-grw5s2pf	1320	28	-	-	HYPH
cord-256444-grw5s2pf	1320	29	and	and	CC
cord-256444-grw5s2pf	1320	30	negative	negative	JJ
cord-256444-grw5s2pf	1320	31	-	-	HYPH
cord-256444-grw5s2pf	1320	32	strand	strand	NN
cord-256444-grw5s2pf	1320	33	RNA	RNA	NNP
cord-256444-grw5s2pf	1320	34	synthesis	synthesis	NN
cord-256444-grw5s2pf	1320	35	(	(	-LRB-
cord-256444-grw5s2pf	1320	36	Liao	Liao	NNP
cord-256444-grw5s2pf	1320	37	and	and	CC
cord-256444-grw5s2pf	1320	38	Lai	Lai	NNP
cord-256444-grw5s2pf	1320	39	,	,	,
cord-256444-grw5s2pf	1320	40	1992	1992	CD
cord-256444-grw5s2pf	1320	41	)	)	-RRB-
cord-256444-grw5s2pf	1320	42	.	.	.
cord-256444-grw5s2pf	1321	1	Recombination	recombination	NN
cord-256444-grw5s2pf	1321	2	can	can	MD
cord-256444-grw5s2pf	1321	3	also	also	RB
cord-256444-grw5s2pf	1321	4	take	take	VB
cord-256444-grw5s2pf	1321	5	place	place	NN
cord-256444-grw5s2pf	1321	6	between	between	IN
cord-256444-grw5s2pf	1321	7	DI	DI	NNP
cord-256444-grw5s2pf	1321	8	RNAs	rna	NNS
cord-256444-grw5s2pf	1321	9	and	and	CC
cord-256444-grw5s2pf	1321	10	viral	viral	JJ
cord-256444-grw5s2pf	1321	11	RNA	RNA	NNP
cord-256444-grw5s2pf	1321	12	reciprocally	reciprocally	RB
cord-256444-grw5s2pf	1321	13	,	,	,
cord-256444-grw5s2pf	1321	14	i.e.	i.e.	FW
cord-256444-grw5s2pf	1321	15	,	,	,
cord-256444-grw5s2pf	1321	16	the	the	DT
cord-256444-grw5s2pf	1321	17	viral	viral	JJ
cord-256444-grw5s2pf	1321	18	RNA	RNA	NNP
cord-256444-grw5s2pf	1321	19	sequence	sequence	NN
cord-256444-grw5s2pf	1321	20	can	can	MD
cord-256444-grw5s2pf	1321	21	be	be	VB
cord-256444-grw5s2pf	1321	22	incorporated	incorporate	VBN
cord-256444-grw5s2pf	1321	23	into	into	IN
cord-256444-grw5s2pf	1321	24	DI	DI	NNP
cord-256444-grw5s2pf	1321	25	RNA	RNA	NNP
cord-256444-grw5s2pf	1321	26	,	,	,
cord-256444-grw5s2pf	1321	27	and	and	CC
cord-256444-grw5s2pf	1321	28	vice	vice	NN
cord-256444-grw5s2pf	1321	29	versa	versa	RB
cord-256444-grw5s2pf	1321	30	,	,	,
cord-256444-grw5s2pf	1321	31	during	during	IN
cord-256444-grw5s2pf	1321	32	viral	viral	JJ
cord-256444-grw5s2pf	1321	33	RNA	RNA	NNP
cord-256444-grw5s2pf	1321	34	replication	replication	NN
cord-256444-grw5s2pf	1321	35	.	.	.
cord-256444-grw5s2pf	1322	1	The	the	DT
cord-256444-grw5s2pf	1322	2	incorporation	incorporation	NN
cord-256444-grw5s2pf	1322	3	of	of	IN
cord-256444-grw5s2pf	1322	4	a	a	DT
cord-256444-grw5s2pf	1322	5	helper	helper	NN
cord-256444-grw5s2pf	1322	6	viral	viral	JJ
cord-256444-grw5s2pf	1322	7	RNA	RNA	NNP
cord-256444-grw5s2pf	1322	8	sequence	sequence	NN
cord-256444-grw5s2pf	1322	9	into	into	IN
cord-256444-grw5s2pf	1322	10	DI	DI	NNP
cord-256444-grw5s2pf	1322	11	RNA	RNA	NNP
cord-256444-grw5s2pf	1322	12	accounts	account	VBZ
cord-256444-grw5s2pf	1322	13	at	at	IN
cord-256444-grw5s2pf	1322	14	least	least	JJS
cord-256444-grw5s2pf	1322	15	partially	partially	RB
cord-256444-grw5s2pf	1322	16	for	for	IN
cord-256444-grw5s2pf	1322	17	the	the	DT
cord-256444-grw5s2pf	1322	18	continuous	continuous	JJ
cord-256444-grw5s2pf	1322	19	evolution	evolution	NN
cord-256444-grw5s2pf	1322	20	of	of	IN
cord-256444-grw5s2pf	1322	21	MHV	MHV	NNP
cord-256444-grw5s2pf	1322	22	DI	DI	NNP
cord-256444-grw5s2pf	1322	23	RNA	RNA	NNP
cord-256444-grw5s2pf	1322	24	species	specie	NNS
cord-256444-grw5s2pf	1322	25	during	during	IN
cord-256444-grw5s2pf	1322	26	serial	serial	JJ
cord-256444-grw5s2pf	1322	27	passages	passage	NNS
cord-256444-grw5s2pf	1322	28	in	in	IN
cord-256444-grw5s2pf	1322	29	cultured	cultured	JJ
cord-256444-grw5s2pf	1322	30	cells	cell	NNS
cord-256444-grw5s2pf	1322	31	(	(	-LRB-
cord-256444-grw5s2pf	1322	32	see	see	VB
cord-256444-grw5s2pf	1322	33	the	the	DT
cord-256444-grw5s2pf	1322	34	next	next	JJ
cord-256444-grw5s2pf	1322	35	section	section	NN
cord-256444-grw5s2pf	1322	36	)	)	-RRB-
cord-256444-grw5s2pf	1322	37	.	.	.
cord-256444-grw5s2pf	1323	1	This	this	DT
cord-256444-grw5s2pf	1323	2	phenomenon	phenomenon	NN
cord-256444-grw5s2pf	1323	3	also	also	RB
cord-256444-grw5s2pf	1323	4	explains	explain	VBZ
cord-256444-grw5s2pf	1323	5	why	why	WRB
cord-256444-grw5s2pf	1323	6	some	some	DT
cord-256444-grw5s2pf	1323	7	genetic	genetic	JJ
cord-256444-grw5s2pf	1323	8	markers	marker	NNS
cord-256444-grw5s2pf	1323	9	in	in	IN
cord-256444-grw5s2pf	1323	10	the	the	DT
cord-256444-grw5s2pf	1323	11	DI	DI	NNP
cord-256444-grw5s2pf	1323	12	RNA	RNA	NNP
cord-256444-grw5s2pf	1323	13	were	be	VBD
cord-256444-grw5s2pf	1323	14	rapidly	rapidly	RB
cord-256444-grw5s2pf	1323	15	replaced	replace	VBN
cord-256444-grw5s2pf	1323	16	by	by	IN
cord-256444-grw5s2pf	1323	17	the	the	DT
cord-256444-grw5s2pf	1323	18	helper	helper	NN
cord-256444-grw5s2pf	1323	19	viral	viral	JJ
cord-256444-grw5s2pf	1323	20	RNA	RNA	NNP
cord-256444-grw5s2pf	1323	21	sequences	sequence	NNS
cord-256444-grw5s2pf	1323	22	during	during	IN
cord-256444-grw5s2pf	1323	23	DI	DI	NNP
cord-256444-grw5s2pf	1323	24	RNA	RNA	NNP
cord-256444-grw5s2pf	1323	25	replication	replication	NN
cord-256444-grw5s2pf	1323	26	Kim	Kim	NNP
cord-256444-grw5s2pf	1323	27	et	et	NNP
cord-256444-grw5s2pf	1323	28	al	al	NNP
cord-256444-grw5s2pf	1323	29	.	.	NNP
cord-256444-grw5s2pf	1323	30	,	,	,
cord-256444-grw5s2pf	1323	31	1993a	1993a	CD
cord-256444-grw5s2pf	1323	32	)	)	-RRB-
cord-256444-grw5s2pf	1323	33	.	.	.
cord-256444-grw5s2pf	1324	1	On	on	IN
cord-256444-grw5s2pf	1324	2	the	the	DT
cord-256444-grw5s2pf	1324	3	other	other	JJ
cord-256444-grw5s2pf	1324	4	hand	hand	NN
cord-256444-grw5s2pf	1324	5	,	,	,
cord-256444-grw5s2pf	1324	6	the	the	DT
cord-256444-grw5s2pf	1324	7	incorporation	incorporation	NN
cord-256444-grw5s2pf	1324	8	of	of	IN
cord-256444-grw5s2pf	1324	9	DI	DI	NNP
cord-256444-grw5s2pf	1324	10	RNA	RNA	NNP
cord-256444-grw5s2pf	1324	11	sequences	sequence	NNS
cord-256444-grw5s2pf	1324	12	into	into	IN
cord-256444-grw5s2pf	1324	13	viral	viral	JJ
cord-256444-grw5s2pf	1324	14	RNA	rna	NN
cord-256444-grw5s2pf	1324	15	by	by	IN
cord-256444-grw5s2pf	1324	16	recombination	recombination	NN
cord-256444-grw5s2pf	1324	17	provides	provide	VBZ
cord-256444-grw5s2pf	1324	18	an	an	DT
cord-256444-grw5s2pf	1324	19	important	important	JJ
cord-256444-grw5s2pf	1324	20	tool	tool	NN
cord-256444-grw5s2pf	1324	21	to	to	TO
cord-256444-grw5s2pf	1324	22	introduce	introduce	VB
cord-256444-grw5s2pf	1324	23	desired	desire	VBN
cord-256444-grw5s2pf	1324	24	sequences	sequence	NNS
cord-256444-grw5s2pf	1324	25	into	into	IN
cord-256444-grw5s2pf	1324	26	the	the	DT
cord-256444-grw5s2pf	1324	27	viral	viral	JJ
cord-256444-grw5s2pf	1324	28	genome	genome	NN
cord-256444-grw5s2pf	1324	29	.	.	.
cord-256444-grw5s2pf	1325	1	For	for	IN
cord-256444-grw5s2pf	1325	2	example	example	NN
cord-256444-grw5s2pf	1325	3	,	,	,
cord-256444-grw5s2pf	1325	4	when	when	WRB
cord-256444-grw5s2pf	1325	5	an	an	DT
cord-256444-grw5s2pf	1325	6	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1325	7	7	7	CD
cord-256444-grw5s2pf	1325	8	or	or	CC
cord-256444-grw5s2pf	1325	9	DI	DI	NNP
cord-256444-grw5s2pf	1325	10	RNA	RNA	NNP
cord-256444-grw5s2pf	1325	11	containing	contain	VBG
cord-256444-grw5s2pf	1325	12	the	the	DT
cord-256444-grw5s2pf	1325	13	N	n	CD
cord-256444-grw5s2pf	1325	14	gene	gene	NN
cord-256444-grw5s2pf	1325	15	of	of	IN
cord-256444-grw5s2pf	1325	16	MHV	MHV	NNP
cord-256444-grw5s2pf	1325	17	was	be	VBD
cord-256444-grw5s2pf	1325	18	transfected	transfecte	VBN
cord-256444-grw5s2pf	1325	19	into	into	IN
cord-256444-grw5s2pf	1325	20	cells	cell	NNS
cord-256444-grw5s2pf	1325	21	infected	infect	VBN
cord-256444-grw5s2pf	1325	22	with	with	IN
cord-256444-grw5s2pf	1325	23	an	an	DT
cord-256444-grw5s2pf	1325	24	MHV	MHV	NNP
cord-256444-grw5s2pf	1325	25	ts	ts	NN
cord-256444-grw5s2pf	1325	26	mutant	mutant	NN
cord-256444-grw5s2pf	1325	27	containing	contain	VBG
cord-256444-grw5s2pf	1325	28	a	a	DT
cord-256444-grw5s2pf	1325	29	defective	defective	JJ
cord-256444-grw5s2pf	1325	30	N	n	CD
cord-256444-grw5s2pf	1325	31	protein	protein	NN
cord-256444-grw5s2pf	1325	32	,	,	,
cord-256444-grw5s2pf	1325	33	recombination	recombination	NN
cord-256444-grw5s2pf	1325	34	occurred	occur	VBD
cord-256444-grw5s2pf	1325	35	between	between	IN
cord-256444-grw5s2pf	1325	36	the	the	DT
cord-256444-grw5s2pf	1325	37	DI	DI	NNP
cord-256444-grw5s2pf	1325	38	RNA	RNA	NNP
cord-256444-grw5s2pf	1325	39	and	and	CC
cord-256444-grw5s2pf	1325	40	the	the	DT
cord-256444-grw5s2pf	1325	41	wild	wild	JJ
cord-256444-grw5s2pf	1325	42	-	-	HYPH
cord-256444-grw5s2pf	1325	43	type	type	NN
cord-256444-grw5s2pf	1325	44	viral	viral	JJ
cord-256444-grw5s2pf	1325	45	RNA	RNA	NNP
cord-256444-grw5s2pf	1325	46	,	,	,
cord-256444-grw5s2pf	1325	47	resulting	result	VBG
cord-256444-grw5s2pf	1325	48	in	in	IN
cord-256444-grw5s2pf	1325	49	recombinant	recombinant	JJ
cord-256444-grw5s2pf	1325	50	viruses	virus	NNS
cord-256444-grw5s2pf	1325	51	which	which	WDT
cord-256444-grw5s2pf	1325	52	had	have	VBD
cord-256444-grw5s2pf	1325	53	a	a	DT
cord-256444-grw5s2pf	1325	54	wild	wild	JJ
cord-256444-grw5s2pf	1325	55	-	-	HYPH
cord-256444-grw5s2pf	1325	56	type	type	NN
cord-256444-grw5s2pf	1325	57	RNA	RNA	NNP
cord-256444-grw5s2pf	1325	58	sequence	sequence	NN
cord-256444-grw5s2pf	1325	59	derived	derive	VBN
cord-256444-grw5s2pf	1325	60	from	from	IN
cord-256444-grw5s2pf	1325	61	the	the	DT
cord-256444-grw5s2pf	1325	62	transfected	transfecte	VBN
cord-256444-grw5s2pf	1325	63	RNA	RNA	NNP
cord-256444-grw5s2pf	1325	64	in	in	IN
cord-256444-grw5s2pf	1325	65	place	place	NN
cord-256444-grw5s2pf	1325	66	of	of	IN
cord-256444-grw5s2pf	1325	67	the	the	DT
cord-256444-grw5s2pf	1325	68	defective	defective	JJ
cord-256444-grw5s2pf	1325	69	N	n	CD
cord-256444-grw5s2pf	1325	70	gene	gene	NN
cord-256444-grw5s2pf	1325	71	(	(	-LRB-
cord-256444-grw5s2pf	1325	72	Koetzner	Koetzner	NNP
cord-256444-grw5s2pf	1325	73	et	et	NNP
cord-256444-grw5s2pf	1325	74	al	al	NNP
cord-256444-grw5s2pf	1325	75	.	.	NNP
cord-256444-grw5s2pf	1325	76	,	,	,
cord-256444-grw5s2pf	1325	77	1992	1992	CD
cord-256444-grw5s2pf	1325	78	;	;	:
cord-256444-grw5s2pf	1325	79	van	van	NNP
cord-256444-grw5s2pf	1325	80	der	der	NNP
cord-256444-grw5s2pf	1325	81	Most	Most	NNP
cord-256444-grw5s2pf	1325	82	et	et	NNP
cord-256444-grw5s2pf	1325	83	al	al	NNP
cord-256444-grw5s2pf	1325	84	.	.	NNP
cord-256444-grw5s2pf	1325	85	,	,	,
cord-256444-grw5s2pf	1325	86	1992	1992	CD
cord-256444-grw5s2pf	1325	87	;	;	.
cord-256444-grw5s2pf	1326	1	Masters	Masters	NNPS
cord-256444-grw5s2pf	1326	2	et	et	NNP
cord-256444-grw5s2pf	1326	3	al	al	NNP
cord-256444-grw5s2pf	1326	4	.	.	NNP
cord-256444-grw5s2pf	1326	5	,	,	,
cord-256444-grw5s2pf	1326	6	1994	1994	CD
cord-256444-grw5s2pf	1327	1	;	;	:
cord-256444-grw5s2pf	1327	2	Peng	Peng	NNP
cord-256444-grw5s2pf	1327	3	et	et	NNP
cord-256444-grw5s2pf	1327	4	al	al	NNP
cord-256444-grw5s2pf	1327	5	.	.	NNP
cord-256444-grw5s2pf	1327	6	,	,	,
cord-256444-grw5s2pf	1327	7	1995a	1995a	CD
cord-256444-grw5s2pf	1327	8	)	)	-RRB-
cord-256444-grw5s2pf	1327	9	.	.	.
cord-256444-grw5s2pf	1328	1	An	an	DT
cord-256444-grw5s2pf	1328	2	MHV	MHV	NNP
cord-256444-grw5s2pf	1328	3	recombinant	recombinant	JJ
cord-256444-grw5s2pf	1328	4	containing	contain	VBG
cord-256444-grw5s2pf	1328	5	a	a	DT
cord-256444-grw5s2pf	1328	6	chimeric	chimeric	JJ
cord-256444-grw5s2pf	1328	7	N	n	CD
cord-256444-grw5s2pf	1328	8	protein	protein	NN
cord-256444-grw5s2pf	1328	9	of	of	IN
cord-256444-grw5s2pf	1328	10	BCV	BCV	NNP
cord-256444-grw5s2pf	1328	11	and	and	CC
cord-256444-grw5s2pf	1328	12	MHV	MHV	NNP
cord-256444-grw5s2pf	1328	13	has	have	VBZ
cord-256444-grw5s2pf	1328	14	also	also	RB
cord-256444-grw5s2pf	1328	15	been	be	VBN
cord-256444-grw5s2pf	1328	16	derived	derive	VBN
cord-256444-grw5s2pf	1328	17	by	by	IN
cord-256444-grw5s2pf	1328	18	this	this	DT
cord-256444-grw5s2pf	1328	19	RNA	RNA	NNP
cord-256444-grw5s2pf	1328	20	recombination	recombination	NN
cord-256444-grw5s2pf	1328	21	strategy	strategy	NN
cord-256444-grw5s2pf	1328	22	(	(	-LRB-
cord-256444-grw5s2pf	1328	23	Peng	Peng	NNP
cord-256444-grw5s2pf	1328	24	et	et	NNP
cord-256444-grw5s2pf	1328	25	al	al	NNP
cord-256444-grw5s2pf	1328	26	.	.	NNP
cord-256444-grw5s2pf	1328	27	,	,	,
cord-256444-grw5s2pf	1328	28	199513	199513	CD
cord-256444-grw5s2pf	1328	29	)	)	-RRB-
cord-256444-grw5s2pf	1328	30	.	.	.
cord-256444-grw5s2pf	1329	1	This	this	DT
cord-256444-grw5s2pf	1329	2	targeted	target	VBN
cord-256444-grw5s2pf	1329	3	RNA	rna	NN
cord-256444-grw5s2pf	1329	4	recombination	recombination	NN
cord-256444-grw5s2pf	1329	5	promises	promise	NNS
cord-256444-grw5s2pf	1329	6	to	to	TO
cord-256444-grw5s2pf	1329	7	be	be	VB
cord-256444-grw5s2pf	1329	8	a	a	DT
cord-256444-grw5s2pf	1329	9	powerful	powerful	JJ
cord-256444-grw5s2pf	1329	10	tool	tool	NN
cord-256444-grw5s2pf	1329	11	.	.	.
cord-256444-grw5s2pf	1330	1	Recombination	recombination	NN
cord-256444-grw5s2pf	1330	2	is	be	VBZ
cord-256444-grw5s2pf	1330	3	thus	thus	RB
cord-256444-grw5s2pf	1330	4	one	one	CD
cord-256444-grw5s2pf	1330	5	of	of	IN
cord-256444-grw5s2pf	1330	6	the	the	DT
cord-256444-grw5s2pf	1330	7	most	most	RBS
cord-256444-grw5s2pf	1330	8	unique	unique	JJ
cord-256444-grw5s2pf	1330	9	aspects	aspect	NNS
cord-256444-grw5s2pf	1330	10	of	of	IN
cord-256444-grw5s2pf	1330	11	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1330	12	biology	biology	NN
cord-256444-grw5s2pf	1330	13	.	.	.
cord-256444-grw5s2pf	1331	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1331	2	can	can	MD
cord-256444-grw5s2pf	1331	3	potentially	potentially	RB
cord-256444-grw5s2pf	1331	4	provide	provide	VB
cord-256444-grw5s2pf	1331	5	a	a	DT
cord-256444-grw5s2pf	1331	6	genetic	genetic	JJ
cord-256444-grw5s2pf	1331	7	mechanism	mechanism	NN
cord-256444-grw5s2pf	1331	8	by	by	IN
cord-256444-grw5s2pf	1331	9	which	which	WDT
cord-256444-grw5s2pf	1331	10	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1331	11	maintain	maintain	VBP
cord-256444-grw5s2pf	1331	12	their	-PRON-	PRP$
cord-256444-grw5s2pf	1331	13	sequence	sequence	NN
cord-256444-grw5s2pf	1331	14	integrity	integrity	NN
cord-256444-grw5s2pf	1331	15	.	.	.
cord-256444-grw5s2pf	1332	1	In	in	IN
cord-256444-grw5s2pf	1332	2	view	view	NN
cord-256444-grw5s2pf	1332	3	of	of	IN
cord-256444-grw5s2pf	1332	4	the	the	DT
cord-256444-grw5s2pf	1332	5	large	large	JJ
cord-256444-grw5s2pf	1332	6	size	size	NN
cord-256444-grw5s2pf	1332	7	of	of	IN
cord-256444-grw5s2pf	1332	8	the	the	DT
cord-256444-grw5s2pf	1332	9	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1332	10	RNA	RNA	NNP
cord-256444-grw5s2pf	1332	11	,	,	,
cord-256444-grw5s2pf	1332	12	it	-PRON-	PRP
cord-256444-grw5s2pf	1332	13	is	be	VBZ
cord-256444-grw5s2pf	1332	14	predictable	predictable	JJ
cord-256444-grw5s2pf	1332	15	that	that	IN
cord-256444-grw5s2pf	1332	16	most	most	JJS
cord-256444-grw5s2pf	1332	17	of	of	IN
cord-256444-grw5s2pf	1332	18	the	the	DT
cord-256444-grw5s2pf	1332	19	viral	viral	JJ
cord-256444-grw5s2pf	1332	20	RNA	RNA	NNP
cord-256444-grw5s2pf	1332	21	molecules	molecule	NNS
cord-256444-grw5s2pf	1332	22	would	would	MD
cord-256444-grw5s2pf	1332	23	contain	contain	VB
cord-256444-grw5s2pf	1332	24	mutations	mutation	NNS
cord-256444-grw5s2pf	1332	25	due	due	JJ
cord-256444-grw5s2pf	1332	26	to	to	IN
cord-256444-grw5s2pf	1332	27	the	the	DT
cord-256444-grw5s2pf	1332	28	high	high	JJ
cord-256444-grw5s2pf	1332	29	error	error	NN
cord-256444-grw5s2pf	1332	30	frequencies	frequency	NNS
cord-256444-grw5s2pf	1332	31	of	of	IN
cord-256444-grw5s2pf	1332	32	RNA	RNA	NNP
cord-256444-grw5s2pf	1332	33	polymerases	polymerase	NNS
cord-256444-grw5s2pf	1332	34	;	;	:
cord-256444-grw5s2pf	1332	35	recombination	recombination	NN
cord-256444-grw5s2pf	1332	36	may	may	MD
cord-256444-grw5s2pf	1332	37	provide	provide	VB
cord-256444-grw5s2pf	1332	38	a	a	DT
cord-256444-grw5s2pf	1332	39	repair	repair	NN
cord-256444-grw5s2pf	1332	40	mechanism	mechanism	NN
cord-256444-grw5s2pf	1332	41	for	for	IN
cord-256444-grw5s2pf	1332	42	the	the	DT
cord-256444-grw5s2pf	1332	43	virus	virus	NN
cord-256444-grw5s2pf	1332	44	(	(	-LRB-
cord-256444-grw5s2pf	1332	45	Lai	Lai	NNP
cord-256444-grw5s2pf	1332	46	,	,	,
cord-256444-grw5s2pf	1332	47	1992	1992	CD
cord-256444-grw5s2pf	1332	48	)	)	-RRB-
cord-256444-grw5s2pf	1332	49	.	.	.
cord-256444-grw5s2pf	1333	1	Similar	similar	JJ
cord-256444-grw5s2pf	1333	2	to	to	IN
cord-256444-grw5s2pf	1333	3	most	most	JJS
cord-256444-grw5s2pf	1333	4	RNA	RNA	NNP
cord-256444-grw5s2pf	1333	5	viruses	virus	NNS
cord-256444-grw5s2pf	1333	6	,	,	,
cord-256444-grw5s2pf	1333	7	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1333	8	can	can	MD
cord-256444-grw5s2pf	1333	9	readily	readily	RB
cord-256444-grw5s2pf	1333	10	generate	generate	VB
cord-256444-grw5s2pf	1333	11	DI	DI	NNP
cord-256444-grw5s2pf	1333	12	particles	particle	NNS
cord-256444-grw5s2pf	1333	13	when	when	WRB
cord-256444-grw5s2pf	1333	14	viruses	virus	NNS
cord-256444-grw5s2pf	1333	15	are	be	VBP
cord-256444-grw5s2pf	1333	16	passaged	passage	VBN
cord-256444-grw5s2pf	1333	17	in	in	IN
cord-256444-grw5s2pf	1333	18	tissue	tissue	NN
cord-256444-grw5s2pf	1333	19	culture	culture	NN
cord-256444-grw5s2pf	1333	20	at	at	IN
cord-256444-grw5s2pf	1333	21	a	a	DT
cord-256444-grw5s2pf	1333	22	high	high	JJ
cord-256444-grw5s2pf	1333	23	multiplicity	multiplicity	NN
cord-256444-grw5s2pf	1333	24	of	of	IN
cord-256444-grw5s2pf	1333	25	infection	infection	NN
cord-256444-grw5s2pf	1333	26	.	.	.
cord-256444-grw5s2pf	1334	1	This	this	DT
cord-256444-grw5s2pf	1334	2	has	have	VBZ
cord-256444-grw5s2pf	1334	3	been	be	VBN
cord-256444-grw5s2pf	1334	4	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	1334	5	for	for	IN
cord-256444-grw5s2pf	1334	6	MHV	MHV	NNP
cord-256444-grw5s2pf	1334	7	,	,	,
cord-256444-grw5s2pf	1334	8	IBV	IBV	NNP
cord-256444-grw5s2pf	1334	9	,	,	,
cord-256444-grw5s2pf	1334	10	and	and	CC
cord-256444-grw5s2pf	1334	11	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1334	12	.	.	.
cord-256444-grw5s2pf	1335	1	When	when	WRB
cord-256444-grw5s2pf	1335	2	MHV	MHV	NNP
cord-256444-grw5s2pf	1335	3	was	be	VBD
cord-256444-grw5s2pf	1335	4	serially	serially	RB
cord-256444-grw5s2pf	1335	5	passaged	passage	VBN
cord-256444-grw5s2pf	1335	6	,	,	,
cord-256444-grw5s2pf	1335	7	different	different	JJ
cord-256444-grw5s2pf	1335	8	types	type	NNS
cord-256444-grw5s2pf	1335	9	of	of	IN
cord-256444-grw5s2pf	1335	10	DI	DI	NNP
cord-256444-grw5s2pf	1335	11	RNA	RNA	NNP
cord-256444-grw5s2pf	1335	12	appeared	appear	VBD
cord-256444-grw5s2pf	1335	13	at	at	IN
cord-256444-grw5s2pf	1335	14	different	different	JJ
cord-256444-grw5s2pf	1335	15	passage	passage	NN
cord-256444-grw5s2pf	1335	16	levels	level	NNS
cord-256444-grw5s2pf	1335	17	,	,	,
cord-256444-grw5s2pf	1335	18	suggesting	suggest	VBG
cord-256444-grw5s2pf	1335	19	that	that	IN
cord-256444-grw5s2pf	1335	20	DI	DI	NNP
cord-256444-grw5s2pf	1335	21	RNAs	rna	NNS
cord-256444-grw5s2pf	1335	22	continue	continue	VBP
cord-256444-grw5s2pf	1335	23	to	to	TO
cord-256444-grw5s2pf	1335	24	evolve	evolve	VB
cord-256444-grw5s2pf	1335	25	and	and	CC
cord-256444-grw5s2pf	1335	26	that	that	IN
cord-256444-grw5s2pf	1335	27	new	new	JJ
cord-256444-grw5s2pf	1335	28	DIs	dis	NN
cord-256444-grw5s2pf	1335	29	have	have	VBP
cord-256444-grw5s2pf	1335	30	a	a	DT
cord-256444-grw5s2pf	1335	31	selective	selective	JJ
cord-256444-grw5s2pf	1335	32	advantage	advantage	NN
cord-256444-grw5s2pf	1335	33	under	under	IN
cord-256444-grw5s2pf	1335	34	the	the	DT
cord-256444-grw5s2pf	1335	35	evolving	evolve	VBG
cord-256444-grw5s2pf	1335	36	cellular	cellular	JJ
cord-256444-grw5s2pf	1335	37	conditions	condition	NNS
cord-256444-grw5s2pf	1335	38	.	.	.
cord-256444-grw5s2pf	1336	1	However	however	RB
cord-256444-grw5s2pf	1336	2	,	,	,
cord-256444-grw5s2pf	1336	3	the	the	DT
cord-256444-grw5s2pf	1336	4	IBV	IBV	NNP
cord-256444-grw5s2pf	1336	5	and	and	CC
cord-256444-grw5s2pf	1336	6	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1336	7	DIs	dis	VBP
cord-256444-grw5s2pf	1336	8	appear	appear	VBP
cord-256444-grw5s2pf	1336	9	to	to	TO
cord-256444-grw5s2pf	1336	10	be	be	VB
cord-256444-grw5s2pf	1336	11	more	more	RBR
cord-256444-grw5s2pf	1336	12	stable	stable	JJ
cord-256444-grw5s2pf	1337	1	(	(	-LRB-
cord-256444-grw5s2pf	1337	2	Penzes	Penzes	NNP
cord-256444-grw5s2pf	1337	3	et	et	NNP
cord-256444-grw5s2pf	1337	4	al	al	NNP
cord-256444-grw5s2pf	1337	5	.	.	NNP
cord-256444-grw5s2pf	1337	6	,	,	,
cord-256444-grw5s2pf	1337	7	1994	1994	CD
cord-256444-grw5s2pf	1337	8	;	;	:
cord-256444-grw5s2pf	1337	9	Mendez	Mendez	NNP
cord-256444-grw5s2pf	1337	10	et	et	NNP
cord-256444-grw5s2pf	1337	11	al	al	NNP
cord-256444-grw5s2pf	1337	12	.	.	NNP
cord-256444-grw5s2pf	1337	13	,	,	,
cord-256444-grw5s2pf	1337	14	1996	1996	CD
cord-256444-grw5s2pf	1337	15	)	)	-RRB-
cord-256444-grw5s2pf	1337	16	.	.	.
cord-256444-grw5s2pf	1338	1	The	the	DT
cord-256444-grw5s2pf	1338	2	generation	generation	NN
cord-256444-grw5s2pf	1338	3	of	of	IN
cord-256444-grw5s2pf	1338	4	DI	DI	NNP
cord-256444-grw5s2pf	1338	5	RNAs	rna	NNS
cord-256444-grw5s2pf	1338	6	is	be	VBZ
cord-256444-grw5s2pf	1338	7	probably	probably	RB
cord-256444-grw5s2pf	1338	8	caused	cause	VBN
cord-256444-grw5s2pf	1338	9	by	by	IN
cord-256444-grw5s2pf	1338	10	polymerase	polymerase	NN
cord-256444-grw5s2pf	1338	11	jumping	jump	VBG
cord-256444-grw5s2pf	1338	12	during	during	IN
cord-256444-grw5s2pf	1338	13	RNA	RNA	NNP
cord-256444-grw5s2pf	1338	14	replication	replication	NN
cord-256444-grw5s2pf	1338	15	or	or	CC
cord-256444-grw5s2pf	1338	16	nonhomologous	nonhomologous	NNP
cord-256444-grw5s2pf	1338	17	RNA	RNA	NNP
cord-256444-grw5s2pf	1338	18	recombination	recombination	NN
cord-256444-grw5s2pf	1338	19	.	.	.
cord-256444-grw5s2pf	1339	1	Although	although	IN
cord-256444-grw5s2pf	1339	2	no	no	DT
cord-256444-grw5s2pf	1339	3	sequence	sequence	NN
cord-256444-grw5s2pf	1339	4	homology	homology	NN
cord-256444-grw5s2pf	1339	5	exists	exist	VBZ
cord-256444-grw5s2pf	1339	6	at	at	IN
cord-256444-grw5s2pf	1339	7	the	the	DT
cord-256444-grw5s2pf	1339	8	fusion	fusion	NN
cord-256444-grw5s2pf	1339	9	sites	site	NNS
cord-256444-grw5s2pf	1339	10	of	of	IN
cord-256444-grw5s2pf	1339	11	different	different	JJ
cord-256444-grw5s2pf	1339	12	RNA	RNA	NNP
cord-256444-grw5s2pf	1339	13	regions	region	NNS
cord-256444-grw5s2pf	1339	14	within	within	IN
cord-256444-grw5s2pf	1339	15	the	the	DT
cord-256444-grw5s2pf	1339	16	DI	DI	NNP
cord-256444-grw5s2pf	1339	17	RNA	RNA	NNP
cord-256444-grw5s2pf	1339	18	,	,	,
cord-256444-grw5s2pf	1339	19	a	a	DT
cord-256444-grw5s2pf	1339	20	high	high	JJ
cord-256444-grw5s2pf	1339	21	degree	degree	NN
cord-256444-grw5s2pf	1339	22	of	of	IN
cord-256444-grw5s2pf	1339	23	potential	potential	JJ
cord-256444-grw5s2pf	1339	24	secondary	secondary	JJ
cord-256444-grw5s2pf	1339	25	structure	structure	NN
cord-256444-grw5s2pf	1339	26	does	do	VBZ
cord-256444-grw5s2pf	1339	27	exist	exist	VB
cord-256444-grw5s2pf	1339	28	at	at	IN
cord-256444-grw5s2pf	1339	29	some	some	DT
cord-256444-grw5s2pf	1339	30	of	of	IN
cord-256444-grw5s2pf	1339	31	its	-PRON-	PRP$
cord-256444-grw5s2pf	1339	32	RNA	RNA	NNP
cord-256444-grw5s2pf	1339	33	fusion	fusion	NN
cord-256444-grw5s2pf	1339	34	sites	site	NNS
cord-256444-grw5s2pf	1339	35	(	(	-LRB-
cord-256444-grw5s2pf	1339	36	Makino	Makino	NNP
cord-256444-grw5s2pf	1339	37	et	et	NNP
cord-256444-grw5s2pf	1339	38	al	al	NNP
cord-256444-grw5s2pf	1339	39	.	.	NNP
cord-256444-grw5s2pf	1339	40	,	,	,
cord-256444-grw5s2pf	1339	41	1988b	1988b	CD
cord-256444-grw5s2pf	1339	42	)	)	-RRB-
cord-256444-grw5s2pf	1339	43	,	,	,
cord-256444-grw5s2pf	1339	44	which	which	WDT
cord-256444-grw5s2pf	1339	45	may	may	MD
cord-256444-grw5s2pf	1339	46	have	have	VB
cord-256444-grw5s2pf	1339	47	facilitated	facilitate	VBN
cord-256444-grw5s2pf	1339	48	the	the	DT
cord-256444-grw5s2pf	1339	49	pausing	pausing	NN
cord-256444-grw5s2pf	1339	50	and	and	CC
cord-256444-grw5s2pf	1339	51	template	template	NN
cord-256444-grw5s2pf	1339	52	switching	switching	NN
cord-256444-grw5s2pf	1339	53	of	of	IN
cord-256444-grw5s2pf	1339	54	RNA	RNA	NNP
cord-256444-grw5s2pf	1339	55	polymerase	polymerase	NN
cord-256444-grw5s2pf	1339	56	during	during	IN
cord-256444-grw5s2pf	1339	57	synthesis	synthesis	NN
cord-256444-grw5s2pf	1339	58	.	.	.
cord-256444-grw5s2pf	1340	1	If	if	IN
cord-256444-grw5s2pf	1340	2	nonhomologous	nonhomologous	JJ
cord-256444-grw5s2pf	1340	3	recombination	recombination	NN
cord-256444-grw5s2pf	1340	4	is	be	VBZ
cord-256444-grw5s2pf	1340	5	involved	involve	VBN
cord-256444-grw5s2pf	1340	6	in	in	IN
cord-256444-grw5s2pf	1340	7	generating	generate	VBG
cord-256444-grw5s2pf	1340	8	DI	DI	NNP
cord-256444-grw5s2pf	1340	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1340	10	,	,	,
cord-256444-grw5s2pf	1340	11	it	-PRON-	PRP
cord-256444-grw5s2pf	1340	12	probably	probably	RB
cord-256444-grw5s2pf	1340	13	occurs	occur	VBZ
cord-256444-grw5s2pf	1340	14	between	between	IN
cord-256444-grw5s2pf	1340	15	two	two	CD
cord-256444-grw5s2pf	1340	16	different	different	JJ
cord-256444-grw5s2pf	1340	17	RNA	rna	NN
cord-256444-grw5s2pf	1340	18	molecules	molecule	NNS
cord-256444-grw5s2pf	1340	19	because	because	IN
cord-256444-grw5s2pf	1340	20	DI	DI	NNP
cord-256444-grw5s2pf	1340	21	RNAs	rna	NNS
cord-256444-grw5s2pf	1340	22	are	be	VBP
cord-256444-grw5s2pf	1340	23	generated	generate	VBN
cord-256444-grw5s2pf	1340	24	only	only	RB
cord-256444-grw5s2pf	1340	25	at	at	IN
cord-256444-grw5s2pf	1340	26	high	high	JJ
cord-256444-grw5s2pf	1340	27	multiplicity	multiplicity	NN
cord-256444-grw5s2pf	1340	28	of	of	IN
cord-256444-grw5s2pf	1340	29	infection	infection	NN
cord-256444-grw5s2pf	1340	30	.	.	.
cord-256444-grw5s2pf	1341	1	Recombination	recombination	NN
cord-256444-grw5s2pf	1341	2	between	between	IN
cord-256444-grw5s2pf	1341	3	an	an	DT
cord-256444-grw5s2pf	1341	4	existing	exist	VBG
cord-256444-grw5s2pf	1341	5	DI	DI	NNP
cord-256444-grw5s2pf	1341	6	RNA	RNA	NNP
cord-256444-grw5s2pf	1341	7	and	and	CC
cord-256444-grw5s2pf	1341	8	helper	helper	NN
cord-256444-grw5s2pf	1341	9	virus	virus	NN
cord-256444-grw5s2pf	1341	10	RNA	RNA	NNP
cord-256444-grw5s2pf	1341	11	has	have	VBZ
cord-256444-grw5s2pf	1341	12	been	be	VBN
cord-256444-grw5s2pf	1341	13	shown	show	VBN
cord-256444-grw5s2pf	1341	14	to	to	TO
cord-256444-grw5s2pf	1341	15	contribute	contribute	VB
cord-256444-grw5s2pf	1341	16	to	to	IN
cord-256444-grw5s2pf	1341	17	the	the	DT
cord-256444-grw5s2pf	1341	18	evolution	evolution	NN
cord-256444-grw5s2pf	1341	19	of	of	IN
cord-256444-grw5s2pf	1341	20	MHV	MHV	NNP
cord-256444-grw5s2pf	1341	21	DI	DI	NNP
cord-256444-grw5s2pf	1341	22	RNAs	rna	NNS
cord-256444-grw5s2pf	1341	23	during	during	IN
cord-256444-grw5s2pf	1341	24	virus	virus	NN
cord-256444-grw5s2pf	1341	25	passages	passage	NNS
cord-256444-grw5s2pf	1341	26	.	.	.
cord-256444-grw5s2pf	1342	1	The	the	DT
cord-256444-grw5s2pf	1342	2	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1342	3	DI	DI	NNP
cord-256444-grw5s2pf	1342	4	RNAs	rna	NNS
cord-256444-grw5s2pf	1342	5	can	can	MD
cord-256444-grw5s2pf	1342	6	be	be	VB
cord-256444-grw5s2pf	1342	7	grouped	group	VBN
cord-256444-grw5s2pf	1342	8	into	into	IN
cord-256444-grw5s2pf	1342	9	three	three	CD
cord-256444-grw5s2pf	1342	10	types	type	NNS
cord-256444-grw5s2pf	1342	11	.	.	.
cord-256444-grw5s2pf	1343	1	The	the	DT
cord-256444-grw5s2pf	1343	2	first	first	JJ
cord-256444-grw5s2pf	1343	3	type	type	NN
cord-256444-grw5s2pf	1343	4	is	be	VBZ
cord-256444-grw5s2pf	1343	5	of	of	IN
cord-256444-grw5s2pf	1343	6	nearly	nearly	RB
cord-256444-grw5s2pf	1343	7	genomic	genomic	JJ
cord-256444-grw5s2pf	1343	8	size	size	NN
cord-256444-grw5s2pf	1343	9	and	and	CC
cord-256444-grw5s2pf	1343	10	is	be	VBZ
cord-256444-grw5s2pf	1343	11	typified	typify	VBN
cord-256444-grw5s2pf	1343	12	by	by	IN
cord-256444-grw5s2pf	1343	13	DIssA	DIssA	NNP
cord-256444-grw5s2pf	1343	14	RNA	RNA	NNP
cord-256444-grw5s2pf	1343	15	of	of	IN
cord-256444-grw5s2pf	1343	16	MHV	MHV	NNP
cord-256444-grw5s2pf	1343	17	.	.	.
cord-256444-grw5s2pf	1344	1	This	this	DT
cord-256444-grw5s2pf	1344	2	DI	DI	NNP
cord-256444-grw5s2pf	1344	3	RNA	RNA	NNP
cord-256444-grw5s2pf	1344	4	is	be	VBZ
cord-256444-grw5s2pf	1344	5	efficiently	efficiently	RB
cord-256444-grw5s2pf	1344	6	packaged	package	VBN
cord-256444-grw5s2pf	1344	7	into	into	IN
cord-256444-grw5s2pf	1344	8	virus	virus	NN
cord-256444-grw5s2pf	1344	9	particles	particle	NNS
cord-256444-grw5s2pf	1344	10	and	and	CC
cord-256444-grw5s2pf	1344	11	contains	contain	VBZ
cord-256444-grw5s2pf	1344	12	several	several	JJ
cord-256444-grw5s2pf	1344	13	deletions	deletion	NNS
cord-256444-grw5s2pf	1344	14	in	in	IN
cord-256444-grw5s2pf	1344	15	the	the	DT
cord-256444-grw5s2pf	1344	16	viral	viral	JJ
cord-256444-grw5s2pf	1344	17	genome	genome	NN
cord-256444-grw5s2pf	1344	18	,	,	,
cord-256444-grw5s2pf	1344	19	but	but	CC
cord-256444-grw5s2pf	1344	20	it	-PRON-	PRP
cord-256444-grw5s2pf	1344	21	contains	contain	VBZ
cord-256444-grw5s2pf	1344	22	a	a	DT
cord-256444-grw5s2pf	1344	23	functional	functional	JJ
cord-256444-grw5s2pf	1344	24	gene	gene	NN
cord-256444-grw5s2pf	1344	25	1	1	CD
cord-256444-grw5s2pf	1344	26	,	,	,
cord-256444-grw5s2pf	1344	27	which	which	WDT
cord-256444-grw5s2pf	1344	28	encodes	encode	VBZ
cord-256444-grw5s2pf	1344	29	RNA	RNA	NNP
cord-256444-grw5s2pf	1344	30	polymerase	polymerase	NN
cord-256444-grw5s2pf	1344	31	,	,	,
cord-256444-grw5s2pf	1344	32	and	and	CC
cord-256444-grw5s2pf	1344	33	a	a	DT
cord-256444-grw5s2pf	1344	34	functional	functional	JJ
cord-256444-grw5s2pf	1344	35	gene	gene	NN
cord-256444-grw5s2pf	1344	36	7	7	CD
cord-256444-grw5s2pf	1344	37	,	,	,
cord-256444-grw5s2pf	1344	38	which	which	WDT
cord-256444-grw5s2pf	1344	39	encodes	encode	VBZ
cord-256444-grw5s2pf	1344	40	N	n	CD
cord-256444-grw5s2pf	1344	41	protein	protein	NN
cord-256444-grw5s2pf	1344	42	.	.	.
cord-256444-grw5s2pf	1345	1	These	these	DT
cord-256444-grw5s2pf	1345	2	two	two	CD
cord-256444-grw5s2pf	1345	3	functional	functional	JJ
cord-256444-grw5s2pf	1345	4	gene	gene	NN
cord-256444-grw5s2pf	1345	5	products	product	NNS
cord-256444-grw5s2pf	1345	6	are	be	VBP
cord-256444-grw5s2pf	1345	7	sufficient	sufficient	JJ
cord-256444-grw5s2pf	1345	8	to	to	TO
cord-256444-grw5s2pf	1345	9	support	support	VB
cord-256444-grw5s2pf	1345	10	DI	DI	NNP
cord-256444-grw5s2pf	1345	11	RNA	RNA	NNP
cord-256444-grw5s2pf	1345	12	replication	replication	NN
cord-256444-grw5s2pf	1345	13	(	(	-LRB-
cord-256444-grw5s2pf	1345	14	K.	K.	NNP
cord-256444-grw5s2pf	1345	15	H.	H.	NNP
cord-256444-grw5s2pf	1345	16	;	;	:
cord-256444-grw5s2pf	1345	17	thus	thus	RB
cord-256444-grw5s2pf	1345	18	,	,	,
cord-256444-grw5s2pf	1345	19	this	this	DT
cord-256444-grw5s2pf	1345	20	type	type	NN
cord-256444-grw5s2pf	1345	21	of	of	IN
cord-256444-grw5s2pf	1345	22	DI	DI	NNP
cord-256444-grw5s2pf	1345	23	RNA	RNA	NNP
cord-256444-grw5s2pf	1345	24	can	can	MD
cord-256444-grw5s2pf	1345	25	replicate	replicate	VB
cord-256444-grw5s2pf	1345	26	without	without	IN
cord-256444-grw5s2pf	1345	27	a	a	DT
cord-256444-grw5s2pf	1345	28	helper	helper	NN
cord-256444-grw5s2pf	1345	29	virus	virus	NN
cord-256444-grw5s2pf	1345	30	(	(	-LRB-
cord-256444-grw5s2pf	1345	31	Makino	Makino	NNP
cord-256444-grw5s2pf	1345	32	et	et	NNP
cord-256444-grw5s2pf	1345	33	al	al	NNP
cord-256444-grw5s2pf	1345	34	.	.	NNP
cord-256444-grw5s2pf	1345	35	,	,	,
cord-256444-grw5s2pf	1345	36	1988a	1988a	CD
cord-256444-grw5s2pf	1345	37	;	;	:
cord-256444-grw5s2pf	1345	38	K.	K.	NNP
cord-256444-grw5s2pf	1345	39	H.	H.	NNP
cord-256444-grw5s2pf	1345	40	Kim	Kim	NNP
cord-256444-grw5s2pf	1345	41	and	and	CC
cord-256444-grw5s2pf	1345	42	Makino	Makino	NNP
cord-256444-grw5s2pf	1345	43	,	,	,
cord-256444-grw5s2pf	1345	44	1995	1995	CD
cord-256444-grw5s2pf	1345	45	)	)	-RRB-
cord-256444-grw5s2pf	1345	46	.	.	.
cord-256444-grw5s2pf	1346	1	By	by	IN
cord-256444-grw5s2pf	1346	2	definition	definition	NN
cord-256444-grw5s2pf	1346	3	,	,	,
cord-256444-grw5s2pf	1346	4	it	-PRON-	PRP
cord-256444-grw5s2pf	1346	5	is	be	VBZ
cord-256444-grw5s2pf	1346	6	not	not	RB
cord-256444-grw5s2pf	1346	7	a	a	DT
cord-256444-grw5s2pf	1346	8	DI	DI	NNP
cord-256444-grw5s2pf	1346	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1346	10	,	,	,
cord-256444-grw5s2pf	1346	11	inasmuch	inasmuch	IN
cord-256444-grw5s2pf	1346	12	as	as	IN
cord-256444-grw5s2pf	1346	13	it	-PRON-	PRP
cord-256444-grw5s2pf	1346	14	is	be	VBZ
cord-256444-grw5s2pf	1346	15	not	not	RB
cord-256444-grw5s2pf	1346	16	defective	defective	JJ
cord-256444-grw5s2pf	1346	17	in	in	IN
cord-256444-grw5s2pf	1346	18	replication	replication	NN
cord-256444-grw5s2pf	1346	19	;	;	:
cord-256444-grw5s2pf	1346	20	however	however	RB
cord-256444-grw5s2pf	1346	21	,	,	,
cord-256444-grw5s2pf	1346	22	because	because	IN
cord-256444-grw5s2pf	1346	23	it	-PRON-	PRP
cord-256444-grw5s2pf	1346	24	is	be	VBZ
cord-256444-grw5s2pf	1346	25	smaller	small	JJR
cord-256444-grw5s2pf	1346	26	than	than	IN
cord-256444-grw5s2pf	1346	27	the	the	DT
cord-256444-grw5s2pf	1346	28	genomic	genomic	JJ
cord-256444-grw5s2pf	1346	29	RNA	RNA	NNP
cord-256444-grw5s2pf	1346	30	and	and	CC
cord-256444-grw5s2pf	1346	31	is	be	VBZ
cord-256444-grw5s2pf	1346	32	produced	produce	VBN
cord-256444-grw5s2pf	1346	33	at	at	IN
cord-256444-grw5s2pf	1346	34	a	a	DT
cord-256444-grw5s2pf	1346	35	high	high	JJ
cord-256444-grw5s2pf	1346	36	multiplicity	multiplicity	NN
cord-256444-grw5s2pf	1346	37	of	of	IN
cord-256444-grw5s2pf	1346	38	infection	infection	NN
cord-256444-grw5s2pf	1346	39	,	,	,
cord-256444-grw5s2pf	1346	40	it	-PRON-	PRP
cord-256444-grw5s2pf	1346	41	is	be	VBZ
cord-256444-grw5s2pf	1346	42	classified	classify	VBN
cord-256444-grw5s2pf	1346	43	as	as	IN
cord-256444-grw5s2pf	1346	44	a	a	DT
cord-256444-grw5s2pf	1346	45	DI	DI	NNP
cord-256444-grw5s2pf	1346	46	RNA	RNA	NNP
cord-256444-grw5s2pf	1346	47	.	.	.
cord-256444-grw5s2pf	1347	1	This	this	DT
cord-256444-grw5s2pf	1347	2	type	type	NN
cord-256444-grw5s2pf	1347	3	of	of	IN
cord-256444-grw5s2pf	1347	4	DI	DI	NNP
cord-256444-grw5s2pf	1347	5	is	be	VBZ
cord-256444-grw5s2pf	1347	6	unique	unique	JJ
cord-256444-grw5s2pf	1347	7	to	to	IN
cord-256444-grw5s2pf	1347	8	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1347	9	.	.	.
cord-256444-grw5s2pf	1348	1	A	a	DT
cord-256444-grw5s2pf	1348	2	22-kb	22-kb	CD
cord-256444-grw5s2pf	1348	3	DI	DI	NNP
cord-256444-grw5s2pf	1348	4	RNA	RNA	NNP
cord-256444-grw5s2pf	1348	5	has	have	VBZ
cord-256444-grw5s2pf	1348	6	been	be	VBN
cord-256444-grw5s2pf	1348	7	described	describe	VBN
cord-256444-grw5s2pf	1348	8	for	for	IN
cord-256444-grw5s2pf	1348	9	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1348	10	(	(	-LRB-
cord-256444-grw5s2pf	1348	11	Mendez	Mendez	NNP
cord-256444-grw5s2pf	1348	12	et	et	NNP
cord-256444-grw5s2pf	1348	13	al	al	NNP
cord-256444-grw5s2pf	1348	14	.	.	NNP
cord-256444-grw5s2pf	1348	15	,	,	,
cord-256444-grw5s2pf	1348	16	19961	19961	CD
cord-256444-grw5s2pf	1348	17	,	,	,
cord-256444-grw5s2pf	1348	18	but	but	CC
cord-256444-grw5s2pf	1348	19	whether	whether	IN
cord-256444-grw5s2pf	1348	20	it	-PRON-	PRP
cord-256444-grw5s2pf	1348	21	can	can	MD
cord-256444-grw5s2pf	1348	22	replicate	replicate	VB
cord-256444-grw5s2pf	1348	23	in	in	IN
cord-256444-grw5s2pf	1348	24	the	the	DT
cord-256444-grw5s2pf	1348	25	absence	absence	NN
cord-256444-grw5s2pf	1348	26	of	of	IN
cord-256444-grw5s2pf	1348	27	a	a	DT
cord-256444-grw5s2pf	1348	28	helper	helper	NN
cord-256444-grw5s2pf	1348	29	virus	virus	NN
cord-256444-grw5s2pf	1348	30	has	have	VBZ
cord-256444-grw5s2pf	1348	31	not	not	RB
cord-256444-grw5s2pf	1348	32	been	be	VBN
cord-256444-grw5s2pf	1348	33	examined	examine	VBN
cord-256444-grw5s2pf	1348	34	.	.	.
cord-256444-grw5s2pf	1349	1	The	the	DT
cord-256444-grw5s2pf	1349	2	second	second	JJ
cord-256444-grw5s2pf	1349	3	type	type	NN
cord-256444-grw5s2pf	1349	4	DI	DI	NNP
cord-256444-grw5s2pf	1349	5	RNA	RNA	NNP
cord-256444-grw5s2pf	1349	6	is	be	VBZ
cord-256444-grw5s2pf	1349	7	typified	typify	VBN
cord-256444-grw5s2pf	1349	8	by	by	IN
cord-256444-grw5s2pf	1349	9	DIssE	DIssE	NNP
cord-256444-grw5s2pf	1349	10	of	of	IN
cord-256444-grw5s2pf	1349	11	MHV	MHV	NNP
cord-256444-grw5s2pf	1349	12	(	(	-LRB-
cord-256444-grw5s2pf	1349	13	Makino	Makino	NNP
cord-256444-grw5s2pf	1349	14	et	et	NNP
cord-256444-grw5s2pf	1349	15	al	al	NNP
cord-256444-grw5s2pf	1349	16	.	.	NNP
cord-256444-grw5s2pf	1349	17	,	,	,
cord-256444-grw5s2pf	1349	18	198813	198813	CD
cord-256444-grw5s2pf	1349	19	)	)	-RRB-
cord-256444-grw5s2pf	1349	20	.	.	.
cord-256444-grw5s2pf	1350	1	This	this	DT
cord-256444-grw5s2pf	1350	2	DI	DI	NNP
cord-256444-grw5s2pf	1350	3	RNA	RNA	NNP
cord-256444-grw5s2pf	1350	4	is	be	VBZ
cord-256444-grw5s2pf	1350	5	truly	truly	RB
cord-256444-grw5s2pf	1350	6	defective	defective	JJ
cord-256444-grw5s2pf	1350	7	and	and	CC
cord-256444-grw5s2pf	1350	8	can	can	MD
cord-256444-grw5s2pf	1350	9	replicate	replicate	VB
cord-256444-grw5s2pf	1350	10	only	only	RB
cord-256444-grw5s2pf	1350	11	in	in	IN
cord-256444-grw5s2pf	1350	12	the	the	DT
cord-256444-grw5s2pf	1350	13	presence	presence	NN
cord-256444-grw5s2pf	1350	14	of	of	IN
cord-256444-grw5s2pf	1350	15	helper	helper	NN
cord-256444-grw5s2pf	1350	16	viruses	virus	NNS
cord-256444-grw5s2pf	1350	17	.	.	.
cord-256444-grw5s2pf	1351	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1351	2	replicates	replicate	VBZ
cord-256444-grw5s2pf	1351	3	very	very	RB
cord-256444-grw5s2pf	1351	4	efficiently	efficiently	RB
cord-256444-grw5s2pf	1351	5	,	,	,
cord-256444-grw5s2pf	1351	6	but	but	CC
cord-256444-grw5s2pf	1351	7	is	be	VBZ
cord-256444-grw5s2pf	1351	8	poorly	poorly	RB
cord-256444-grw5s2pf	1351	9	packaged	package	VBN
cord-256444-grw5s2pf	1351	10	into	into	IN
cord-256444-grw5s2pf	1351	11	virus	virus	NN
cord-256444-grw5s2pf	1351	12	particles	particle	NNS
cord-256444-grw5s2pf	1351	13	because	because	IN
cord-256444-grw5s2pf	1351	14	it	-PRON-	PRP
cord-256444-grw5s2pf	1351	15	lacks	lack	VBZ
cord-256444-grw5s2pf	1351	16	a	a	DT
cord-256444-grw5s2pf	1351	17	specific	specific	JJ
cord-256444-grw5s2pf	1351	18	RNA	rna	NN
cord-256444-grw5s2pf	1351	19	-	-	HYPH
cord-256444-grw5s2pf	1351	20	packaging	packaging	NN
cord-256444-grw5s2pf	1351	21	signal	signal	NN
cord-256444-grw5s2pf	1351	22	.	.	.
cord-256444-grw5s2pf	1352	1	This	this	DT
cord-256444-grw5s2pf	1352	2	type	type	NN
cord-256444-grw5s2pf	1352	3	of	of	IN
cord-256444-grw5s2pf	1352	4	DI	DI	NNP
cord-256444-grw5s2pf	1352	5	RNA	RNA	NNP
cord-256444-grw5s2pf	1352	6	typically	typically	RB
cord-256444-grw5s2pf	1352	7	contains	contain	VBZ
cord-256444-grw5s2pf	1352	8	both	both	CC
cord-256444-grw5s2pf	1352	9	the	the	DT
cord-256444-grw5s2pf	1352	10	5	5	CD
cord-256444-grw5s2pf	1352	11	'	'	''
cord-256444-grw5s2pf	1352	12	and	and	CC
cord-256444-grw5s2pf	1352	13	3	3	CD
cord-256444-grw5s2pf	1352	14	'	'	POS
cord-256444-grw5s2pf	1352	15	ends	end	NNS
cord-256444-grw5s2pf	1352	16	of	of	IN
cord-256444-grw5s2pf	1352	17	the	the	DT
cord-256444-grw5s2pf	1352	18	wild	wild	JJ
cord-256444-grw5s2pf	1352	19	-	-	HYPH
cord-256444-grw5s2pf	1352	20	type	type	NN
cord-256444-grw5s2pf	1352	21	viral	viral	JJ
cord-256444-grw5s2pf	1352	22	RNA	rna	NN
cord-256444-grw5s2pf	1352	23	and	and	CC
cord-256444-grw5s2pf	1352	24	one	one	CD
cord-256444-grw5s2pf	1352	25	or	or	CC
cord-256444-grw5s2pf	1352	26	several	several	JJ
cord-256444-grw5s2pf	1352	27	discontiguous	discontiguous	JJ
cord-256444-grw5s2pf	1352	28	regions	region	NNS
cord-256444-grw5s2pf	1352	29	of	of	IN
cord-256444-grw5s2pf	1352	30	the	the	DT
cord-256444-grw5s2pf	1352	31	wild	wild	JJ
cord-256444-grw5s2pf	1352	32	-	-	HYPH
cord-256444-grw5s2pf	1352	33	type	type	NN
cord-256444-grw5s2pf	1352	34	RNAs	rna	NNS
cord-256444-grw5s2pf	1352	35	.	.	.
cord-256444-grw5s2pf	1353	1	Because	because	IN
cord-256444-grw5s2pf	1353	2	of	of	IN
cord-256444-grw5s2pf	1353	3	the	the	DT
cord-256444-grw5s2pf	1353	4	high	high	JJ
cord-256444-grw5s2pf	1353	5	efficiency	efficiency	NN
cord-256444-grw5s2pf	1353	6	of	of	IN
cord-256444-grw5s2pf	1353	7	replication	replication	NN
cord-256444-grw5s2pf	1353	8	,	,	,
cord-256444-grw5s2pf	1353	9	this	this	DT
cord-256444-grw5s2pf	1353	10	type	type	NN
cord-256444-grw5s2pf	1353	11	of	of	IN
cord-256444-grw5s2pf	1353	12	DI	DI	NNP
cord-256444-grw5s2pf	1353	13	can	can	MD
cord-256444-grw5s2pf	1353	14	still	still	RB
cord-256444-grw5s2pf	1353	15	be	be	VB
cord-256444-grw5s2pf	1353	16	serially	serially	RB
cord-256444-grw5s2pf	1353	17	passaged	passage	VBN
cord-256444-grw5s2pf	1353	18	in	in	IN
cord-256444-grw5s2pf	1353	19	tissue	tissue	NN
cord-256444-grw5s2pf	1353	20	culture	culture	NN
cord-256444-grw5s2pf	1353	21	for	for	IN
cord-256444-grw5s2pf	1353	22	at	at	RB
cord-256444-grw5s2pf	1353	23	least	least	RBS
cord-256444-grw5s2pf	1353	24	several	several	JJ
cord-256444-grw5s2pf	1353	25	passages	passage	NNS
cord-256444-grw5s2pf	1353	26	,	,	,
cord-256444-grw5s2pf	1353	27	probably	probably	RB
cord-256444-grw5s2pf	1353	28	because	because	IN
cord-256444-grw5s2pf	1353	29	a	a	DT
cord-256444-grw5s2pf	1353	30	small	small	JJ
cord-256444-grw5s2pf	1353	31	amount	amount	NN
cord-256444-grw5s2pf	1353	32	of	of	IN
cord-256444-grw5s2pf	1353	33	DI	DI	NNP
cord-256444-grw5s2pf	1353	34	RNA	RNA	NNP
cord-256444-grw5s2pf	1353	35	can	can	MD
cord-256444-grw5s2pf	1353	36	be	be	VB
cord-256444-grw5s2pf	1353	37	nonspecifically	nonspecifically	RB
cord-256444-grw5s2pf	1353	38	packaged	package	VBN
cord-256444-grw5s2pf	1353	39	into	into	IN
cord-256444-grw5s2pf	1353	40	the	the	DT
cord-256444-grw5s2pf	1353	41	virion	virion	NN
cord-256444-grw5s2pf	1353	42	.	.	.
cord-256444-grw5s2pf	1354	1	The	the	DT
cord-256444-grw5s2pf	1354	2	third	third	JJ
cord-256444-grw5s2pf	1354	3	type	type	NN
cord-256444-grw5s2pf	1354	4	of	of	IN
cord-256444-grw5s2pf	1354	5	DI	DI	NNP
cord-256444-grw5s2pf	1354	6	RNA	RNA	NNP
cord-256444-grw5s2pf	1354	7	is	be	VBZ
cord-256444-grw5s2pf	1354	8	represented	represent	VBN
cord-256444-grw5s2pf	1354	9	by	by	IN
cord-256444-grw5s2pf	1354	10	DIssF	DIssF	NNP
cord-256444-grw5s2pf	1354	11	of	of	IN
cord-256444-grw5s2pf	1354	12	MHV	MHV	NNP
cord-256444-grw5s2pf	1354	13	-	-	HYPH
cord-256444-grw5s2pf	1354	14	JHM	JHM	NNP
cord-256444-grw5s2pf	1354	15	(	(	-LRB-
cord-256444-grw5s2pf	1354	16	Makino	Makino	NNP
cord-256444-grw5s2pf	1354	17	et	et	NNP
cord-256444-grw5s2pf	1354	18	al	al	NNP
cord-256444-grw5s2pf	1354	19	.	.	NNP
cord-256444-grw5s2pf	1354	20	,	,	,
cord-256444-grw5s2pf	1354	21	1990	1990	CD
cord-256444-grw5s2pf	1354	22	)	)	-RRB-
cord-256444-grw5s2pf	1354	23	and	and	CC
cord-256444-grw5s2pf	1354	24	DI	DI	NNP
cord-256444-grw5s2pf	1354	25	-	-	,
cord-256444-grw5s2pf	1354	26	a	a	NN
cord-256444-grw5s2pf	1354	27	of	of	IN
cord-256444-grw5s2pf	1354	28	MHV	MHV	NNP
cord-256444-grw5s2pf	1354	29	A59	A59	NNP
cord-256444-grw5s2pf	1354	30	(	(	-LRB-
cord-256444-grw5s2pf	1354	31	van	van	NNP
cord-256444-grw5s2pf	1354	32	der	der	NNP
cord-256444-grw5s2pf	1354	33	Most	Most	NNP
cord-256444-grw5s2pf	1354	34	et	et	NNP
cord-256444-grw5s2pf	1354	35	al	al	NNP
cord-256444-grw5s2pf	1354	36	.	.	NNP
cord-256444-grw5s2pf	1354	37	,	,	,
cord-256444-grw5s2pf	1354	38	1991	1991	CD
cord-256444-grw5s2pf	1354	39	)	)	-RRB-
cord-256444-grw5s2pf	1354	40	.	.	.
cord-256444-grw5s2pf	1355	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1355	2	is	be	VBZ
cord-256444-grw5s2pf	1355	3	similar	similar	JJ
cord-256444-grw5s2pf	1355	4	to	to	IN
cord-256444-grw5s2pf	1355	5	the	the	DT
cord-256444-grw5s2pf	1355	6	second	second	JJ
cord-256444-grw5s2pf	1355	7	type	type	NN
cord-256444-grw5s2pf	1355	8	but	but	CC
cord-256444-grw5s2pf	1355	9	contains	contain	VBZ
cord-256444-grw5s2pf	1355	10	an	an	DT
cord-256444-grw5s2pf	1355	11	RNA	RNA	NNP
cord-256444-grw5s2pf	1355	12	-	-	HYPH
cord-256444-grw5s2pf	1355	13	packaging	packaging	NN
cord-256444-grw5s2pf	1355	14	signal	signal	NN
cord-256444-grw5s2pf	1355	15	and	and	CC
cord-256444-grw5s2pf	1355	16	is	be	VBZ
cord-256444-grw5s2pf	1355	17	thus	thus	RB
cord-256444-grw5s2pf	1355	18	packaged	package	VBN
cord-256444-grw5s2pf	1355	19	efficiently	efficiently	RB
cord-256444-grw5s2pf	1355	20	into	into	IN
cord-256444-grw5s2pf	1355	21	virus	virus	NN
cord-256444-grw5s2pf	1355	22	particles	particle	NNS
cord-256444-grw5s2pf	1355	23	.	.	.
cord-256444-grw5s2pf	1356	1	This	this	DT
cord-256444-grw5s2pf	1356	2	type	type	NN
cord-256444-grw5s2pf	1356	3	of	of	IN
cord-256444-grw5s2pf	1356	4	DI	DI	NNP
cord-256444-grw5s2pf	1356	5	RNA	RNA	NNP
cord-256444-grw5s2pf	1356	6	has	have	VBZ
cord-256444-grw5s2pf	1356	7	been	be	VBN
cord-256444-grw5s2pf	1356	8	detected	detect	VBN
cord-256444-grw5s2pf	1356	9	in	in	IN
cord-256444-grw5s2pf	1356	10	IBV	IBV	NNP
cord-256444-grw5s2pf	1356	11	(	(	-LRB-
cord-256444-grw5s2pf	1356	12	Penzes	Penzes	NNP
cord-256444-grw5s2pf	1356	13	et	et	NNP
cord-256444-grw5s2pf	1356	14	al	al	NNP
cord-256444-grw5s2pf	1356	15	.	.	NNP
cord-256444-grw5s2pf	1356	16	,	,	,
cord-256444-grw5s2pf	1356	17	1994	1994	CD
cord-256444-grw5s2pf	1356	18	)	)	-RRB-
cord-256444-grw5s2pf	1356	19	and	and	CC
cord-256444-grw5s2pf	1356	20	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1356	21	(	(	-LRB-
cord-256444-grw5s2pf	1356	22	Mendez	Mendez	NNP
cord-256444-grw5s2pf	1356	23	et	et	NNP
cord-256444-grw5s2pf	1356	24	al	al	NNP
cord-256444-grw5s2pf	1356	25	.	.	NNP
cord-256444-grw5s2pf	1356	26	,	,	,
cord-256444-grw5s2pf	1356	27	1996	1996	CD
cord-256444-grw5s2pf	1356	28	)	)	-RRB-
cord-256444-grw5s2pf	1356	29	.	.	.
cord-256444-grw5s2pf	1357	1	A	a	DT
cord-256444-grw5s2pf	1357	2	small	small	JJ
cord-256444-grw5s2pf	1357	3	DI	DI	NNP
cord-256444-grw5s2pf	1357	4	RNA	RNA	NNP
cord-256444-grw5s2pf	1357	5	(	(	-LRB-
cord-256444-grw5s2pf	1357	6	2.2	2.2	CD
cord-256444-grw5s2pf	1357	7	kb	kb	NNP
cord-256444-grw5s2pf	1357	8	)	)	-RRB-
cord-256444-grw5s2pf	1357	9	of	of	IN
cord-256444-grw5s2pf	1357	10	BCV	BCV	NNP
cord-256444-grw5s2pf	1357	11	may	may	MD
cord-256444-grw5s2pf	1357	12	also	also	RB
cord-256444-grw5s2pf	1357	13	belong	belong	VB
cord-256444-grw5s2pf	1357	14	to	to	IN
cord-256444-grw5s2pf	1357	15	this	this	DT
cord-256444-grw5s2pf	1357	16	type	type	NN
cord-256444-grw5s2pf	1357	17	,	,	,
cord-256444-grw5s2pf	1357	18	but	but	CC
cord-256444-grw5s2pf	1357	19	whether	whether	IN
cord-256444-grw5s2pf	1357	20	this	this	DT
cord-256444-grw5s2pf	1357	21	DI	DI	NNP
cord-256444-grw5s2pf	1357	22	RNA	RNA	NNP
cord-256444-grw5s2pf	1357	23	can	can	MD
cord-256444-grw5s2pf	1357	24	be	be	VB
cord-256444-grw5s2pf	1357	25	specifically	specifically	RB
cord-256444-grw5s2pf	1357	26	packaged	package	VBN
cord-256444-grw5s2pf	1357	27	into	into	IN
cord-256444-grw5s2pf	1357	28	virion	virion	NN
cord-256444-grw5s2pf	1357	29	is	be	VBZ
cord-256444-grw5s2pf	1357	30	not	not	RB
cord-256444-grw5s2pf	1357	31	certain	certain	JJ
cord-256444-grw5s2pf	1357	32	.	.	.
cord-256444-grw5s2pf	1358	1	All	all	DT
cord-256444-grw5s2pf	1358	2	three	three	CD
cord-256444-grw5s2pf	1358	3	types	type	NNS
cord-256444-grw5s2pf	1358	4	of	of	IN
cord-256444-grw5s2pf	1358	5	DI	DI	NNP
cord-256444-grw5s2pf	1358	6	RNAs	rna	NNS
cord-256444-grw5s2pf	1358	7	contain	contain	VBP
cord-256444-grw5s2pf	1358	8	an	an	DT
cord-256444-grw5s2pf	1358	9	ORF	ORF	NNP
cord-256444-grw5s2pf	1358	10	,	,	,
cord-256444-grw5s2pf	1358	11	which	which	WDT
cord-256444-grw5s2pf	1358	12	encodes	encode	VBZ
cord-256444-grw5s2pf	1358	13	a	a	DT
cord-256444-grw5s2pf	1358	14	protein	protein	NN
cord-256444-grw5s2pf	1358	15	fused	fuse	VBN
cord-256444-grw5s2pf	1358	16	from	from	IN
cord-256444-grw5s2pf	1358	17	two	two	CD
cord-256444-grw5s2pf	1358	18	different	different	JJ
cord-256444-grw5s2pf	1358	19	viral	viral	JJ
cord-256444-grw5s2pf	1358	20	proteins	protein	NNS
cord-256444-grw5s2pf	1358	21	.	.	.
cord-256444-grw5s2pf	1359	1	This	this	DT
cord-256444-grw5s2pf	1359	2	ORF	ORF	NNP
cord-256444-grw5s2pf	1359	3	is	be	VBZ
cord-256444-grw5s2pf	1359	4	not	not	RB
cord-256444-grw5s2pf	1359	5	required	require	VBN
cord-256444-grw5s2pf	1359	6	for	for	IN
cord-256444-grw5s2pf	1359	7	the	the	DT
cord-256444-grw5s2pf	1359	8	replication	replication	NN
cord-256444-grw5s2pf	1359	9	of	of	IN
cord-256444-grw5s2pf	1359	10	MHV	MHV	NNP
cord-256444-grw5s2pf	1359	11	DI	DI	NNP
cord-256444-grw5s2pf	1359	12	RNA	RNA	NNP
cord-256444-grw5s2pf	1360	1	(	(	-LRB-
cord-256444-grw5s2pf	1360	2	Liao	Liao	NNP
cord-256444-grw5s2pf	1360	3	and	and	CC
cord-256444-grw5s2pf	1360	4	Lai	Lai	NNP
cord-256444-grw5s2pf	1360	5	,	,	,
cord-256444-grw5s2pf	1360	6	19'95	19'95	NNP
cord-256444-grw5s2pf	1360	7	)	)	-RRB-
cord-256444-grw5s2pf	1360	8	;	;	:
cord-256444-grw5s2pf	1360	9	nevertheless	nevertheless	RB
cord-256444-grw5s2pf	1360	10	,	,	,
cord-256444-grw5s2pf	1360	11	MHV	MHV	NNP
cord-256444-grw5s2pf	1360	12	DI	DI	NNP
cord-256444-grw5s2pf	1360	13	RNAs	rna	NNS
cord-256444-grw5s2pf	1360	14	with	with	IN
cord-256444-grw5s2pf	1360	15	a	a	DT
cord-256444-grw5s2pf	1360	16	functional	functional	JJ
cord-256444-grw5s2pf	1360	17	ORF	ORF	NNP
cord-256444-grw5s2pf	1360	18	usually	usually	RB
cord-256444-grw5s2pf	1360	19	have	have	VBP
cord-256444-grw5s2pf	1360	20	an	an	DT
cord-256444-grw5s2pf	1360	21	evolutionary	evolutionary	JJ
cord-256444-grw5s2pf	1360	22	advantage	advantage	NN
cord-256444-grw5s2pf	1360	23	over	over	IN
cord-256444-grw5s2pf	1360	24	those	those	DT
cord-256444-grw5s2pf	1360	25	without	without	IN
cord-256444-grw5s2pf	1360	26	one	one	CD
cord-256444-grw5s2pf	1360	27	or	or	CC
cord-256444-grw5s2pf	1360	28	with	with	IN
cord-256444-grw5s2pf	1360	29	a	a	DT
cord-256444-grw5s2pf	1360	30	smaller	small	JJR
cord-256444-grw5s2pf	1360	31	ORF	ORF	NNP
cord-256444-grw5s2pf	1360	32	Kim	Kim	NNP
cord-256444-grw5s2pf	1360	33	et	et	NNP
cord-256444-grw5s2pf	1360	34	al	al	NNP
cord-256444-grw5s2pf	1360	35	.	.	NNP
cord-256444-grw5s2pf	1360	36	,	,	,
cord-256444-grw5s2pf	1360	37	1993a	1993a	CD
cord-256444-grw5s2pf	1360	38	)	)	-RRB-
cord-256444-grw5s2pf	1360	39	.	.	.
cord-256444-grw5s2pf	1361	1	Therefore	therefore	RB
cord-256444-grw5s2pf	1361	2	,	,	,
cord-256444-grw5s2pf	1361	3	a	a	DT
cord-256444-grw5s2pf	1361	4	DI	DI	NNP
cord-256444-grw5s2pf	1361	5	RNA	RNA	NNP
cord-256444-grw5s2pf	1361	6	containing	contain	VBG
cord-256444-grw5s2pf	1361	7	a	a	DT
cord-256444-grw5s2pf	1361	8	short	short	JJ
cord-256444-grw5s2pf	1361	9	ORF	ORF	NNP
cord-256444-grw5s2pf	1361	10	was	be	VBD
cord-256444-grw5s2pf	1361	11	often	often	RB
cord-256444-grw5s2pf	1361	12	rapidly	rapidly	RB
cord-256444-grw5s2pf	1361	13	replaced	replace	VBN
cord-256444-grw5s2pf	1361	14	by	by	IN
cord-256444-grw5s2pf	1361	15	DI	DI	NNP
cord-256444-grw5s2pf	1361	16	RNAs	rna	NNS
cord-256444-grw5s2pf	1361	17	containing	contain	VBG
cord-256444-grw5s2pf	1361	18	a	a	DT
cord-256444-grw5s2pf	1361	19	longer	long	JJR
cord-256444-grw5s2pf	1361	20	ORF	ORF	NNP
cord-256444-grw5s2pf	1361	21	that	that	WDT
cord-256444-grw5s2pf	1361	22	had	have	VBD
cord-256444-grw5s2pf	1361	23	been	be	VBN
cord-256444-grw5s2pf	1361	24	generated	generate	VBN
cord-256444-grw5s2pf	1361	25	by	by	IN
cord-256444-grw5s2pf	1361	26	recombination	recombination	NN
cord-256444-grw5s2pf	1361	27	or	or	CC
cord-256444-grw5s2pf	1361	28	mutation	mutation	NN
cord-256444-grw5s2pf	1361	29	Kim	Kim	NNP
cord-256444-grw5s2pf	1361	30	et	et	NNP
cord-256444-grw5s2pf	1361	31	al	al	NNP
cord-256444-grw5s2pf	1361	32	.	.	NNP
cord-256444-grw5s2pf	1361	33	,	,	,
cord-256444-grw5s2pf	1361	34	1993a	1993a	CD
cord-256444-grw5s2pf	1361	35	)	)	-RRB-
cord-256444-grw5s2pf	1361	36	.	.	.
cord-256444-grw5s2pf	1362	1	The	the	DT
cord-256444-grw5s2pf	1362	2	translatability	translatability	NN
cord-256444-grw5s2pf	1362	3	of	of	IN
cord-256444-grw5s2pf	1362	4	the	the	DT
cord-256444-grw5s2pf	1362	5	ORF	ORF	NNP
cord-256444-grw5s2pf	1362	6	may	may	MD
cord-256444-grw5s2pf	1362	7	be	be	VB
cord-256444-grw5s2pf	1362	8	more	more	RBR
cord-256444-grw5s2pf	1362	9	important	important	JJ
cord-256444-grw5s2pf	1362	10	than	than	IN
cord-256444-grw5s2pf	1362	11	the	the	DT
cord-256444-grw5s2pf	1362	12	nature	nature	NN
cord-256444-grw5s2pf	1362	13	of	of	IN
cord-256444-grw5s2pf	1362	14	the	the	DT
cord-256444-grw5s2pf	1362	15	actual	actual	JJ
cord-256444-grw5s2pf	1362	16	protein	protein	NN
cord-256444-grw5s2pf	1362	17	translated	translate	VBN
cord-256444-grw5s2pf	1362	18	from	from	IN
cord-256444-grw5s2pf	1362	19	this	this	DT
cord-256444-grw5s2pf	1362	20	ORF	ORF	NNP
cord-256444-grw5s2pf	1363	1	(	(	-LRB-
cord-256444-grw5s2pf	1363	2	van	van	NNP
cord-256444-grw5s2pf	1363	3	der	der	NNP
cord-256444-grw5s2pf	1363	4	Most	Most	NNP
cord-256444-grw5s2pf	1363	5	et	et	FW
cord-256444-grw5s2pf	1363	6	al	al	NNP
cord-256444-grw5s2pf	1363	7	.	.	.
cord-256444-grw5s2pf	1364	1	,	,	,
cord-256444-grw5s2pf	1364	2	1995	1995	CD
cord-256444-grw5s2pf	1364	3	)	)	-RRB-
cord-256444-grw5s2pf	1364	4	,	,	,
cord-256444-grw5s2pf	1364	5	suggesting	suggest	VBG
cord-256444-grw5s2pf	1364	6	that	that	IN
cord-256444-grw5s2pf	1364	7	translation	translation	NN
cord-256444-grw5s2pf	1364	8	of	of	IN
cord-256444-grw5s2pf	1364	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1364	10	may	may	MD
cord-256444-grw5s2pf	1364	11	facilitate	facilitate	VB
cord-256444-grw5s2pf	1364	12	RNA	RNA	NNP
cord-256444-grw5s2pf	1364	13	replication	replication	NN
cord-256444-grw5s2pf	1364	14	.	.	.
cord-256444-grw5s2pf	1365	1	Reduction	reduction	NN
cord-256444-grw5s2pf	1365	2	of	of	IN
cord-256444-grw5s2pf	1365	3	the	the	DT
cord-256444-grw5s2pf	1365	4	ORF	ORF	NNP
cord-256444-grw5s2pf	1365	5	of	of	IN
cord-256444-grw5s2pf	1365	6	a	a	DT
cord-256444-grw5s2pf	1365	7	n	n	NNP
cord-256444-grw5s2pf	1365	8	IBV	IBV	NNP
cord-256444-grw5s2pf	1365	9	DI	DI	NNP
cord-256444-grw5s2pf	1365	10	RNA	RNA	NNP
cord-256444-grw5s2pf	1365	11	to	to	IN
cord-256444-grw5s2pf	1365	12	just	just	RB
cord-256444-grw5s2pf	1365	13	20	20	CD
cord-256444-grw5s2pf	1365	14	amino	amino	NN
cord-256444-grw5s2pf	1365	15	acids	acid	NNS
cord-256444-grw5s2pf	1365	16	did	do	VBD
cord-256444-grw5s2pf	1365	17	not	not	RB
cord-256444-grw5s2pf	1365	18	diminish	diminish	VB
cord-256444-grw5s2pf	1365	19	its	-PRON-	PRP$
cord-256444-grw5s2pf	1365	20	capacity	capacity	NN
cord-256444-grw5s2pf	1365	21	to	to	TO
cord-256444-grw5s2pf	1365	22	be	be	VB
cord-256444-grw5s2pf	1365	23	replicated	replicate	VBN
cord-256444-grw5s2pf	1365	24	or	or	CC
cord-256444-grw5s2pf	1365	25	packaged	package	VBN
cord-256444-grw5s2pf	1365	26	(	(	-LRB-
cord-256444-grw5s2pf	1365	27	Penzes	Penzes	NNP
cord-256444-grw5s2pf	1365	28	et	et	NNP
cord-256444-grw5s2pf	1365	29	al	al	NNP
cord-256444-grw5s2pf	1365	30	.	.	NNP
cord-256444-grw5s2pf	1365	31	,	,	,
cord-256444-grw5s2pf	1365	32	1996	1996	CD
cord-256444-grw5s2pf	1365	33	)	)	-RRB-
cord-256444-grw5s2pf	1365	34	.	.	.
cord-256444-grw5s2pf	1366	1	However	however	RB
cord-256444-grw5s2pf	1366	2	,	,	,
cord-256444-grw5s2pf	1366	3	it	-PRON-	PRP
cord-256444-grw5s2pf	1366	4	has	have	VBZ
cord-256444-grw5s2pf	1366	5	been	be	VBN
cord-256444-grw5s2pf	1366	6	shown	show	VBN
cord-256444-grw5s2pf	1366	7	for	for	IN
cord-256444-grw5s2pf	1366	8	a	a	DT
cord-256444-grw5s2pf	1366	9	BCV	BCV	NNP
cord-256444-grw5s2pf	1366	10	DI	DI	NNP
cord-256444-grw5s2pf	1366	11	RNA	RNA	NNP
cord-256444-grw5s2pf	1366	12	that	that	IN
cord-256444-grw5s2pf	1366	13	a	a	DT
cord-256444-grw5s2pf	1366	14	BCV	BCV	NNP
cord-256444-grw5s2pf	1366	15	-	-	HYPH
cord-256444-grw5s2pf	1366	16	specific	specific	JJ
cord-256444-grw5s2pf	1366	17	N	n	CD
cord-256444-grw5s2pf	1366	18	protein	protein	NN
cord-256444-grw5s2pf	1366	19	translated	translate	VBN
cord-256444-grw5s2pf	1366	20	from	from	IN
cord-256444-grw5s2pf	1366	21	the	the	DT
cord-256444-grw5s2pf	1366	22	DI	DI	NNP
cord-256444-grw5s2pf	1366	23	ORF	ORF	NNP
cord-256444-grw5s2pf	1366	24	(	(	-LRB-
cord-256444-grw5s2pf	1366	25	a	a	DT
cord-256444-grw5s2pf	1366	26	cis	cis	NNP
cord-256444-grw5s2pf	1366	27	-	-	HYPH
cord-256444-grw5s2pf	1366	28	acting	act	VBG
cord-256444-grw5s2pf	1366	29	protein	protein	NN
cord-256444-grw5s2pf	1366	30	)	)	-RRB-
cord-256444-grw5s2pf	1366	31	is	be	VBZ
cord-256444-grw5s2pf	1366	32	required	require	VBN
cord-256444-grw5s2pf	1366	33	for	for	IN
cord-256444-grw5s2pf	1366	34	efficient	efficient	JJ
cord-256444-grw5s2pf	1366	35	DI	DI	NNP
cord-256444-grw5s2pf	1366	36	RNA	RNA	NNP
cord-256444-grw5s2pf	1366	37	replication	replication	NN
cord-256444-grw5s2pf	1366	38	.	.	.
cord-256444-grw5s2pf	1367	1	The	the	DT
cord-256444-grw5s2pf	1367	2	variation	variation	NN
cord-256444-grw5s2pf	1367	3	in	in	IN
cord-256444-grw5s2pf	1367	4	the	the	DT
cord-256444-grw5s2pf	1367	5	sequence	sequence	NN
cord-256444-grw5s2pf	1367	6	requirement	requirement	NN
cord-256444-grw5s2pf	1367	7	for	for	IN
cord-256444-grw5s2pf	1367	8	RNA	RNA	NNP
cord-256444-grw5s2pf	1367	9	replication	replication	NN
cord-256444-grw5s2pf	1367	10	of	of	IN
cord-256444-grw5s2pf	1367	11	these	these	DT
cord-256444-grw5s2pf	1367	12	DI	DI	NNP
cord-256444-grw5s2pf	1367	13	RNAs	rna	NNS
cord-256444-grw5s2pf	1367	14	may	may	MD
cord-256444-grw5s2pf	1367	15	be	be	VB
cord-256444-grw5s2pf	1367	16	related	relate	VBN
cord-256444-grw5s2pf	1367	17	to	to	IN
cord-256444-grw5s2pf	1367	18	their	-PRON-	PRP$
cord-256444-grw5s2pf	1367	19	overall	overall	JJ
cord-256444-grw5s2pf	1367	20	RNA	RNA	NNP
cord-256444-grw5s2pf	1367	21	conformation	conformation	NN
cord-256444-grw5s2pf	1367	22	.	.	.
cord-256444-grw5s2pf	1368	1	The	the	DT
cord-256444-grw5s2pf	1368	2	significance	significance	NN
cord-256444-grw5s2pf	1368	3	of	of	IN
cord-256444-grw5s2pf	1368	4	DI	DI	NNP
cord-256444-grw5s2pf	1368	5	RNA	RNA	NNP
cord-256444-grw5s2pf	1368	6	in	in	IN
cord-256444-grw5s2pf	1368	7	the	the	DT
cord-256444-grw5s2pf	1368	8	biology	biology	NN
cord-256444-grw5s2pf	1368	9	and	and	CC
cord-256444-grw5s2pf	1368	10	natural	natural	JJ
cord-256444-grw5s2pf	1368	11	evolution	evolution	NN
cord-256444-grw5s2pf	1368	12	of	of	IN
cord-256444-grw5s2pf	1368	13	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1368	14	is	be	VBZ
cord-256444-grw5s2pf	1368	15	not	not	RB
cord-256444-grw5s2pf	1368	16	known	know	VBN
cord-256444-grw5s2pf	1368	17	.	.	.
cord-256444-grw5s2pf	1369	1	DI	DI	NNP
cord-256444-grw5s2pf	1369	2	RNAs	rna	NNS
cord-256444-grw5s2pf	1369	3	provide	provide	VBP
cord-256444-grw5s2pf	1369	4	useful	useful	JJ
cord-256444-grw5s2pf	1369	5	tools	tool	NNS
cord-256444-grw5s2pf	1369	6	for	for	IN
cord-256444-grw5s2pf	1369	7	studying	study	VBG
cord-256444-grw5s2pf	1369	8	the	the	DT
cord-256444-grw5s2pf	1369	9	sequence	sequence	NN
cord-256444-grw5s2pf	1369	10	and	and	CC
cord-256444-grw5s2pf	1369	11	structural	structural	JJ
cord-256444-grw5s2pf	1369	12	requirements	requirement	NNS
cord-256444-grw5s2pf	1369	13	for	for	IN
cord-256444-grw5s2pf	1369	14	various	various	JJ
cord-256444-grw5s2pf	1369	15	functions	function	NNS
cord-256444-grw5s2pf	1369	16	of	of	IN
cord-256444-grw5s2pf	1369	17	viral	viral	JJ
cord-256444-grw5s2pf	1369	18	genomic	genomic	JJ
cord-256444-grw5s2pf	1369	19	RNA	RNA	NNP
cord-256444-grw5s2pf	1369	20	.	.	.
cord-256444-grw5s2pf	1370	1	As	as	IN
cord-256444-grw5s2pf	1370	2	they	-PRON-	PRP
cord-256444-grw5s2pf	1370	3	contain	contain	VBP
cord-256444-grw5s2pf	1370	4	cis	cis	NNP
cord-256444-grw5s2pf	1370	5	-	-	HYPH
cord-256444-grw5s2pf	1370	6	acting	act	VBG
cord-256444-grw5s2pf	1370	7	signals	signal	NNS
cord-256444-grw5s2pf	1370	8	for	for	IN
cord-256444-grw5s2pf	1370	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1370	10	replication	replication	NN
cord-256444-grw5s2pf	1370	11	,	,	,
cord-256444-grw5s2pf	1370	12	they	-PRON-	PRP
cord-256444-grw5s2pf	1370	13	are	be	VBP
cord-256444-grw5s2pf	1370	14	mini	mini	NN
cord-256444-grw5s2pf	1370	15	-	-	NNS
cord-256444-grw5s2pf	1370	16	versions	version	NNS
cord-256444-grw5s2pf	1370	17	of	of	IN
cord-256444-grw5s2pf	1370	18	the	the	DT
cord-256444-grw5s2pf	1370	19	viral	viral	JJ
cord-256444-grw5s2pf	1370	20	genomic	genomic	JJ
cord-256444-grw5s2pf	1370	21	RNA	RNA	NNP
cord-256444-grw5s2pf	1370	22	.	.	.
cord-256444-grw5s2pf	1371	1	However	however	RB
cord-256444-grw5s2pf	1371	2	,	,	,
cord-256444-grw5s2pf	1371	3	it	-PRON-	PRP
cord-256444-grw5s2pf	1371	4	should	should	MD
cord-256444-grw5s2pf	1371	5	be	be	VB
cord-256444-grw5s2pf	1371	6	cautioned	caution	VBN
cord-256444-grw5s2pf	1371	7	again	again	RB
cord-256444-grw5s2pf	1371	8	that	that	IN
cord-256444-grw5s2pf	1371	9	because	because	IN
cord-256444-grw5s2pf	1371	10	of	of	IN
cord-256444-grw5s2pf	1371	11	the	the	DT
cord-256444-grw5s2pf	1371	12	small	small	JJ
cord-256444-grw5s2pf	1371	13	size	size	NN
cord-256444-grw5s2pf	1371	14	of	of	IN
cord-256444-grw5s2pf	1371	15	the	the	DT
cord-256444-grw5s2pf	1371	16	DI	DI	NNP
cord-256444-grw5s2pf	1371	17	RNA	RNA	NNP
cord-256444-grw5s2pf	1371	18	compared	compare	VBN
cord-256444-grw5s2pf	1371	19	to	to	IN
cord-256444-grw5s2pf	1371	20	the	the	DT
cord-256444-grw5s2pf	1371	21	genomic	genomic	JJ
cord-256444-grw5s2pf	1371	22	RNA	RNA	NNP
cord-256444-grw5s2pf	1371	23	,	,	,
cord-256444-grw5s2pf	1371	24	the	the	DT
cord-256444-grw5s2pf	1371	25	structural	structural	JJ
cord-256444-grw5s2pf	1371	26	requirements	requirement	NNS
cord-256444-grw5s2pf	1371	27	for	for	IN
cord-256444-grw5s2pf	1371	28	various	various	JJ
cord-256444-grw5s2pf	1371	29	RNA	RNA	NNP
cord-256444-grw5s2pf	1371	30	functions	function	NNS
cord-256444-grw5s2pf	1371	31	,	,	,
cord-256444-grw5s2pf	1371	32	as	as	IN
cord-256444-grw5s2pf	1371	33	determined	determine	VBN
cord-256444-grw5s2pf	1371	34	from	from	IN
cord-256444-grw5s2pf	1371	35	the	the	DT
cord-256444-grw5s2pf	1371	36	use	use	NN
cord-256444-grw5s2pf	1371	37	of	of	IN
cord-256444-grw5s2pf	1371	38	DI	DI	NNP
cord-256444-grw5s2pf	1371	39	RNA	RNA	NNP
cord-256444-grw5s2pf	1371	40	constructs	construct	NNS
cord-256444-grw5s2pf	1371	41	,	,	,
cord-256444-grw5s2pf	1371	42	may	may	MD
cord-256444-grw5s2pf	1371	43	be	be	VB
cord-256444-grw5s2pf	1371	44	different	different	JJ
cord-256444-grw5s2pf	1371	45	from	from	IN
cord-256444-grw5s2pf	1371	46	those	those	DT
cord-256444-grw5s2pf	1371	47	of	of	IN
cord-256444-grw5s2pf	1371	48	the	the	DT
cord-256444-grw5s2pf	1371	49	whole	whole	JJ
cord-256444-grw5s2pf	1371	50	viral	viral	JJ
cord-256444-grw5s2pf	1371	51	genome	genome	NN
cord-256444-grw5s2pf	1371	52	.	.	.
cord-256444-grw5s2pf	1372	1	The	the	DT
cord-256444-grw5s2pf	1372	2	following	follow	VBG
cord-256444-grw5s2pf	1372	3	cis	cis	NN
cord-256444-grw5s2pf	1372	4	-	-	HYPH
cord-256444-grw5s2pf	1372	5	acting	act	VBG
cord-256444-grw5s2pf	1372	6	signals	signal	NNS
cord-256444-grw5s2pf	1372	7	for	for	IN
cord-256444-grw5s2pf	1372	8	various	various	JJ
cord-256444-grw5s2pf	1372	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1372	10	functions	function	NNS
cord-256444-grw5s2pf	1372	11	have	have	VBP
cord-256444-grw5s2pf	1372	12	been	be	VBN
cord-256444-grw5s2pf	1372	13	determined	determine	VBN
cord-256444-grw5s2pf	1372	14	using	use	VBG
cord-256444-grw5s2pf	1372	15	various	various	JJ
cord-256444-grw5s2pf	1372	16	DI	DI	NNP
cord-256444-grw5s2pf	1372	17	RNAs	rna	NNS
cord-256444-grw5s2pf	1372	18	:	:	:
cord-256444-grw5s2pf	1372	19	1	1	CD
cord-256444-grw5s2pf	1372	20	.	.	.
cord-256444-grw5s2pf	1373	1	RNA	rna	NN
cord-256444-grw5s2pf	1373	2	-	-	HYPH
cord-256444-grw5s2pf	1373	3	packaging	packaging	NN
cord-256444-grw5s2pf	1373	4	signal	signal	NN
cord-256444-grw5s2pf	1373	5	.	.	.
cord-256444-grw5s2pf	1374	1	In	in	IN
cord-256444-grw5s2pf	1374	2	a	a	DT
cord-256444-grw5s2pf	1374	3	comparison	comparison	NN
cord-256444-grw5s2pf	1374	4	of	of	IN
cord-256444-grw5s2pf	1374	5	MHV	MHV	NNP
cord-256444-grw5s2pf	1374	6	DI	DI	NNP
cord-256444-grw5s2pf	1374	7	RNAs	rna	NNS
cord-256444-grw5s2pf	1374	8	that	that	WDT
cord-256444-grw5s2pf	1374	9	are	be	VBP
cord-256444-grw5s2pf	1374	10	efficiently	efficiently	RB
cord-256444-grw5s2pf	1374	11	and	and	CC
cord-256444-grw5s2pf	1374	12	inefficiently	inefficiently	RB
cord-256444-grw5s2pf	1374	13	packaged	package	VBN
cord-256444-grw5s2pf	1374	14	,	,	,
cord-256444-grw5s2pf	1374	15	it	-PRON-	PRP
cord-256444-grw5s2pf	1374	16	was	be	VBD
cord-256444-grw5s2pf	1374	17	determined	determine	VBN
cord-256444-grw5s2pf	1374	18	that	that	IN
cord-256444-grw5s2pf	1374	19	the	the	DT
cord-256444-grw5s2pf	1374	20	packaging	packaging	NN
cord-256444-grw5s2pf	1374	21	signal	signal	NN
cord-256444-grw5s2pf	1374	22	for	for	IN
cord-256444-grw5s2pf	1374	23	MHV	MHV	NNP
cord-256444-grw5s2pf	1374	24	DI	DI	NNP
cord-256444-grw5s2pf	1374	25	RNA	RNA	NNP
cord-256444-grw5s2pf	1374	26	is	be	VBZ
cord-256444-grw5s2pf	1374	27	localized	localize	VBN
cord-256444-grw5s2pf	1374	28	near	near	IN
cord-256444-grw5s2pf	1374	29	the	the	DT
cord-256444-grw5s2pf	1374	30	3	3	CD
cord-256444-grw5s2pf	1374	31	'	'	NN
cord-256444-grw5s2pf	1374	32	end	end	NN
cord-256444-grw5s2pf	1374	33	of	of	IN
cord-256444-grw5s2pf	1374	34	gene	gene	NN
cord-256444-grw5s2pf	1374	35	1	1	CD
cord-256444-grw5s2pf	1374	36	(	(	-LRB-
cord-256444-grw5s2pf	1374	37	in	in	IN
cord-256444-grw5s2pf	1374	38	the	the	DT
cord-256444-grw5s2pf	1374	39	l	l	NN
cord-256444-grw5s2pf	1374	40	b	b	NNP
cord-256444-grw5s2pf	1374	41	region	region	NN
cord-256444-grw5s2pf	1374	42	,	,	,
cord-256444-grw5s2pf	1374	43	approximately	approximately	RB
cord-256444-grw5s2pf	1374	44	20	20	CD
cord-256444-grw5s2pf	1374	45	kb	kb	NNS
cord-256444-grw5s2pf	1374	46	from	from	IN
cord-256444-grw5s2pf	1374	47	the	the	DT
cord-256444-grw5s2pf	1374	48	5	5	CD
cord-256444-grw5s2pf	1374	49	'	'	NN
cord-256444-grw5s2pf	1374	50	end	end	NN
cord-256444-grw5s2pf	1374	51	)	)	-RRB-
cord-256444-grw5s2pf	1375	1	(	(	-LRB-
cord-256444-grw5s2pf	1375	2	Makino	Makino	NNP
cord-256444-grw5s2pf	1375	3	et	et	NNP
cord-256444-grw5s2pf	1375	4	al	al	NNP
cord-256444-grw5s2pf	1375	5	.	.	.
cord-256444-grw5s2pf	1376	1	,	,	,
cord-256444-grw5s2pf	1376	2	1990	1990	CD
cord-256444-grw5s2pf	1376	3	;	;	:
cord-256444-grw5s2pf	1376	4	van	van	NNP
cord-256444-grw5s2pf	1376	5	der	der	NNP
cord-256444-grw5s2pf	1376	6	Most	Most	NNP
cord-256444-grw5s2pf	1376	7	et	et	FW
cord-256444-grw5s2pf	1376	8	al	al	NNP
cord-256444-grw5s2pf	1376	9	.	.	.
cord-256444-grw5s2pf	1377	1	,	,	,
cord-256444-grw5s2pf	1377	2	1991	1991	CD
cord-256444-grw5s2pf	1377	3	;	;	:
cord-256444-grw5s2pf	1377	4	Fosmire	Fosmire	NNP
cord-256444-grw5s2pf	1377	5	et	et	NNP
cord-256444-grw5s2pf	1377	6	al	al	NNP
cord-256444-grw5s2pf	1377	7	.	.	NNP
cord-256444-grw5s2pf	1377	8	,	,	,
cord-256444-grw5s2pf	1377	9	1992	1992	CD
cord-256444-grw5s2pf	1377	10	)	)	-RRB-
cord-256444-grw5s2pf	1377	11	.	.	.
cord-256444-grw5s2pf	1378	1	This	this	DT
cord-256444-grw5s2pf	1378	2	packaging	packaging	NN
cord-256444-grw5s2pf	1378	3	signal	signal	NN
cord-256444-grw5s2pf	1378	4	forms	form	VBZ
cord-256444-grw5s2pf	1378	5	a	a	DT
cord-256444-grw5s2pf	1378	6	stem	stem	NN
cord-256444-grw5s2pf	1378	7	-	-	HYPH
cord-256444-grw5s2pf	1378	8	loop	loop	NN
cord-256444-grw5s2pf	1378	9	structure	structure	NN
cord-256444-grw5s2pf	1378	10	which	which	WDT
cord-256444-grw5s2pf	1378	11	may	may	MD
cord-256444-grw5s2pf	1378	12	be	be	VB
cord-256444-grw5s2pf	1378	13	required	require	VBN
cord-256444-grw5s2pf	1378	14	for	for	IN
cord-256444-grw5s2pf	1378	15	the	the	DT
cord-256444-grw5s2pf	1378	16	RNA	RNA	NNP
cord-256444-grw5s2pf	1378	17	-	-	HYPH
cord-256444-grw5s2pf	1378	18	packaging	packaging	NN
cord-256444-grw5s2pf	1378	19	activity	activity	NN
cord-256444-grw5s2pf	1378	20	(	(	-LRB-
cord-256444-grw5s2pf	1378	21	Fosmire	Fosmire	NNP
cord-256444-grw5s2pf	1378	22	et	et	NNP
cord-256444-grw5s2pf	1378	23	al	al	NNP
cord-256444-grw5s2pf	1378	24	.	.	NNP
cord-256444-grw5s2pf	1378	25	,	,	,
cord-256444-grw5s2pf	1378	26	1992	1992	CD
cord-256444-grw5s2pf	1378	27	)	)	-RRB-
cord-256444-grw5s2pf	1378	28	.	.	.
cord-256444-grw5s2pf	1379	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1379	2	is	be	VBZ
cord-256444-grw5s2pf	1379	3	necessary	necessary	JJ
cord-256444-grw5s2pf	1379	4	and	and	CC
cord-256444-grw5s2pf	1379	5	sufficient	sufficient	JJ
cord-256444-grw5s2pf	1379	6	for	for	IN
cord-256444-grw5s2pf	1379	7	the	the	DT
cord-256444-grw5s2pf	1379	8	packaging	packaging	NN
cord-256444-grw5s2pf	1379	9	of	of	IN
cord-256444-grw5s2pf	1379	10	DI	DI	NNP
cord-256444-grw5s2pf	1379	11	RNA	RNA	NNP
cord-256444-grw5s2pf	1379	12	or	or	CC
cord-256444-grw5s2pf	1379	13	a	a	DT
cord-256444-grw5s2pf	1379	14	heterologous	heterologous	NNP
cord-256444-grw5s2pf	1379	15	RNA	RNA	NNP
cord-256444-grw5s2pf	1379	16	into	into	IN
cord-256444-grw5s2pf	1379	17	the	the	DT
cord-256444-grw5s2pf	1379	18	virions	virion	NNS
cord-256444-grw5s2pf	1380	1	(	(	-LRB-
cord-256444-grw5s2pf	1380	2	Woo	woo	UH
cord-256444-grw5s2pf	1380	3	et	et	FW
cord-256444-grw5s2pf	1380	4	al	al	NNP
cord-256444-grw5s2pf	1380	5	.	.	NNP
cord-256444-grw5s2pf	1380	6	,	,	,
cord-256444-grw5s2pf	1380	7	1997	1997	CD
cord-256444-grw5s2pf	1380	8	)	)	-RRB-
cord-256444-grw5s2pf	1380	9	.	.	.
cord-256444-grw5s2pf	1381	1	The	the	DT
cord-256444-grw5s2pf	1381	2	fact	fact	NN
cord-256444-grw5s2pf	1381	3	that	that	IN
cord-256444-grw5s2pf	1381	4	this	this	DT
cord-256444-grw5s2pf	1381	5	packaging	packaging	NN
cord-256444-grw5s2pf	1381	6	signal	signal	NN
cord-256444-grw5s2pf	1381	7	is	be	VBZ
cord-256444-grw5s2pf	1381	8	localized	localize	VBN
cord-256444-grw5s2pf	1381	9	in	in	IN
cord-256444-grw5s2pf	1381	10	gene	gene	NN
cord-256444-grw5s2pf	1381	11	1	1	CD
cord-256444-grw5s2pf	1381	12	,	,	,
cord-256444-grw5s2pf	1381	13	which	which	WDT
cord-256444-grw5s2pf	1381	14	is	be	VBZ
cord-256444-grw5s2pf	1381	15	present	present	JJ
cord-256444-grw5s2pf	1381	16	in	in	IN
cord-256444-grw5s2pf	1381	17	genomic	genomic	JJ
cord-256444-grw5s2pf	1381	18	but	but	CC
cord-256444-grw5s2pf	1381	19	not	not	RB
cord-256444-grw5s2pf	1381	20	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	1381	21	RNAs	rna	NNS
cord-256444-grw5s2pf	1381	22	,	,	,
cord-256444-grw5s2pf	1381	23	is	be	VBZ
cord-256444-grw5s2pf	1381	24	consistent	consistent	JJ
cord-256444-grw5s2pf	1381	25	with	with	IN
cord-256444-grw5s2pf	1381	26	the	the	DT
cord-256444-grw5s2pf	1381	27	packaging	packaging	NN
cord-256444-grw5s2pf	1381	28	of	of	IN
cord-256444-grw5s2pf	1381	29	genomic	genomic	JJ
cord-256444-grw5s2pf	1381	30	but	but	CC
cord-256444-grw5s2pf	1381	31	not	not	RB
cord-256444-grw5s2pf	1381	32	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	1381	33	RNAs	rna	NNS
cord-256444-grw5s2pf	1381	34	in	in	IN
cord-256444-grw5s2pf	1381	35	virus	virus	NN
cord-256444-grw5s2pf	1381	36	particles	particle	NNS
cord-256444-grw5s2pf	1381	37	.	.	.
cord-256444-grw5s2pf	1382	1	The	the	DT
cord-256444-grw5s2pf	1382	2	packaging	packaging	NN
cord-256444-grw5s2pf	1382	3	signal	signal	NN
cord-256444-grw5s2pf	1382	4	for	for	IN
cord-256444-grw5s2pf	1382	5	DI	DI	NNP
cord-256444-grw5s2pf	1382	6	RNAs	rna	NNS
cord-256444-grw5s2pf	1382	7	of	of	IN
cord-256444-grw5s2pf	1382	8	other	other	JJ
cord-256444-grw5s2pf	1382	9	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1382	10	has	have	VBZ
cord-256444-grw5s2pf	1382	11	not	not	RB
cord-256444-grw5s2pf	1382	12	been	be	VBN
cord-256444-grw5s2pf	1382	13	determined	determine	VBN
cord-256444-grw5s2pf	1382	14	.	.	.
cord-256444-grw5s2pf	1383	1	However	however	RB
cord-256444-grw5s2pf	1383	2	,	,	,
cord-256444-grw5s2pf	1383	3	some	some	DT
cord-256444-grw5s2pf	1383	4	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1383	5	have	have	VBP
cord-256444-grw5s2pf	1383	6	been	be	VBN
cord-256444-grw5s2pf	1383	7	shown	show	VBN
cord-256444-grw5s2pf	1383	8	to	to	TO
cord-256444-grw5s2pf	1383	9	package	package	VB
cord-256444-grw5s2pf	1383	10	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1383	11	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	1383	12	at	at	IN
cord-256444-grw5s2pf	1383	13	low	low	JJ
cord-256444-grw5s2pf	1383	14	efficiency	efficiency	NN
cord-256444-grw5s2pf	1383	15	(	(	-LRB-
cord-256444-grw5s2pf	1383	16	Sethna	Sethna	NNP
cord-256444-grw5s2pf	1383	17	et	et	NNP
cord-256444-grw5s2pf	1383	18	al	al	NNP
cord-256444-grw5s2pf	1383	19	.	.	NNP
cord-256444-grw5s2pf	1383	20	,	,	,
cord-256444-grw5s2pf	1383	21	1989	1989	CD
cord-256444-grw5s2pf	1383	22	;	;	:
cord-256444-grw5s2pf	1383	23	Hofmann	Hofmann	NNP
cord-256444-grw5s2pf	1383	24	et	et	NNP
cord-256444-grw5s2pf	1383	25	al	al	NNP
cord-256444-grw5s2pf	1383	26	.	.	NNP
cord-256444-grw5s2pf	1383	27	,	,	,
cord-256444-grw5s2pf	1383	28	1990	1990	CD
cord-256444-grw5s2pf	1383	29	;	;	:
cord-256444-grw5s2pf	1383	30	Zhao	Zhao	NNP
cord-256444-grw5s2pf	1383	31	et	et	NNP
cord-256444-grw5s2pf	1383	32	al	al	NNP
cord-256444-grw5s2pf	1383	33	.	.	NNP
cord-256444-grw5s2pf	1383	34	,	,	,
cord-256444-grw5s2pf	1383	35	1993	1993	CD
cord-256444-grw5s2pf	1383	36	)	)	-RRB-
cord-256444-grw5s2pf	1383	37	.	.	.
cord-256444-grw5s2pf	1384	1	These	these	DT
cord-256444-grw5s2pf	1384	2	are	be	VBP
cord-256444-grw5s2pf	1384	3	probably	probably	RB
cord-256444-grw5s2pf	1384	4	packaged	package	VBN
cord-256444-grw5s2pf	1384	5	nonspecifically	nonspecifically	RB
cord-256444-grw5s2pf	1384	6	;	;	:
cord-256444-grw5s2pf	1384	7	however	however	RB
cord-256444-grw5s2pf	1384	8	,	,	,
cord-256444-grw5s2pf	1384	9	the	the	DT
cord-256444-grw5s2pf	1384	10	possibility	possibility	NN
cord-256444-grw5s2pf	1384	11	that	that	IN
cord-256444-grw5s2pf	1384	12	these	these	DT
cord-256444-grw5s2pf	1384	13	viruses	virus	NNS
cord-256444-grw5s2pf	1384	14	may	may	MD
cord-256444-grw5s2pf	1384	15	have	have	VB
cord-256444-grw5s2pf	1384	16	a	a	DT
cord-256444-grw5s2pf	1384	17	different	different	JJ
cord-256444-grw5s2pf	1384	18	RNA	RNA	NNP
cord-256444-grw5s2pf	1384	19	packaging	packaging	NN
cord-256444-grw5s2pf	1384	20	signal	signal	NN
cord-256444-grw5s2pf	1384	21	can	can	MD
cord-256444-grw5s2pf	1384	22	not	not	RB
cord-256444-grw5s2pf	1384	23	yet	yet	RB
cord-256444-grw5s2pf	1384	24	be	be	VB
cord-256444-grw5s2pf	1384	25	ruled	rule	VBN
cord-256444-grw5s2pf	1384	26	out	out	RP
cord-256444-grw5s2pf	1384	27	.	.	.
cord-256444-grw5s2pf	1385	1	Similarly	similarly	RB
cord-256444-grw5s2pf	1385	2	,	,	,
cord-256444-grw5s2pf	1385	3	DI	DI	NNP
cord-256444-grw5s2pf	1385	4	RNAs	rna	NNS
cord-256444-grw5s2pf	1385	5	that	that	WDT
cord-256444-grw5s2pf	1385	6	do	do	VBP
cord-256444-grw5s2pf	1385	7	not	not	RB
cord-256444-grw5s2pf	1385	8	contain	contain	VB
cord-256444-grw5s2pf	1385	9	this	this	DT
cord-256444-grw5s2pf	1385	10	packaging	packaging	NN
cord-256444-grw5s2pf	1385	11	signal	signal	NN
cord-256444-grw5s2pf	1385	12	,	,	,
cord-256444-grw5s2pf	1385	13	such	such	JJ
cord-256444-grw5s2pf	1385	14	as	as	IN
cord-256444-grw5s2pf	1385	15	DIssE	DIssE	NNP
cord-256444-grw5s2pf	1385	16	RNA	RNA	NNP
cord-256444-grw5s2pf	1385	17	of	of	IN
cord-256444-grw5s2pf	1385	18	MHV	MHV	NNP
cord-256444-grw5s2pf	1386	1	(	(	-LRB-
cord-256444-grw5s2pf	1386	2	Makino	Makino	NNP
cord-256444-grw5s2pf	1386	3	et	et	NNP
cord-256444-grw5s2pf	1386	4	al	al	NNP
cord-256444-grw5s2pf	1386	5	.	.	NNP
cord-256444-grw5s2pf	1386	6	,	,	,
cord-256444-grw5s2pf	1386	7	198813	198813	CD
cord-256444-grw5s2pf	1386	8	)	)	-RRB-
cord-256444-grw5s2pf	1386	9	and	and	CC
cord-256444-grw5s2pf	1386	10	DI	DI	NNP
cord-256444-grw5s2pf	1386	11	RNA	RNA	NNP
cord-256444-grw5s2pf	1386	12	of	of	IN
cord-256444-grw5s2pf	1386	13	BCV	BCV	NNP
cord-256444-grw5s2pf	1386	14	Chang	Chang	NNP
cord-256444-grw5s2pf	1386	15	et	et	NNP
cord-256444-grw5s2pf	1386	16	al	al	NNP
cord-256444-grw5s2pf	1386	17	.	.	NNP
cord-256444-grw5s2pf	1386	18	,	,	,
cord-256444-grw5s2pf	1386	19	19961	19961	CD
cord-256444-grw5s2pf	1386	20	,	,	,
cord-256444-grw5s2pf	1386	21	can	can	MD
cord-256444-grw5s2pf	1386	22	be	be	VB
cord-256444-grw5s2pf	1386	23	packaged	package	VBN
cord-256444-grw5s2pf	1386	24	at	at	IN
cord-256444-grw5s2pf	1386	25	low	low	JJ
cord-256444-grw5s2pf	1386	26	efficiency	efficiency	NN
cord-256444-grw5s2pf	1386	27	,	,	,
cord-256444-grw5s2pf	1386	28	thereby	thereby	RB
cord-256444-grw5s2pf	1386	29	maintaining	maintain	VBG
cord-256444-grw5s2pf	1386	30	themselves	-PRON-	PRP
cord-256444-grw5s2pf	1386	31	for	for	IN
cord-256444-grw5s2pf	1386	32	at	at	RB
cord-256444-grw5s2pf	1386	33	least	least	RBS
cord-256444-grw5s2pf	1386	34	several	several	JJ
cord-256444-grw5s2pf	1386	35	passages	passage	NNS
cord-256444-grw5s2pf	1386	36	in	in	IN
cord-256444-grw5s2pf	1386	37	tissue	tissue	NN
cord-256444-grw5s2pf	1386	38	culture	culture	NN
cord-256444-grw5s2pf	1386	39	.	.	.
cord-256444-grw5s2pf	1387	1	For	for	IN
cord-256444-grw5s2pf	1387	2	MHV	MHV	NNP
cord-256444-grw5s2pf	1387	3	DI	DI	NNP
cord-256444-grw5s2pf	1387	4	RNA	RNA	NNP
cord-256444-grw5s2pf	1387	5	,	,	,
cord-256444-grw5s2pf	1387	6	it	-PRON-	PRP
cord-256444-grw5s2pf	1387	7	has	have	VBZ
cord-256444-grw5s2pf	1387	8	been	be	VBN
cord-256444-grw5s2pf	1387	9	shown	show	VBN
cord-256444-grw5s2pf	1387	10	that	that	IN
cord-256444-grw5s2pf	1387	11	only	only	RB
cord-256444-grw5s2pf	1387	12	55	55	CD
cord-256444-grw5s2pf	1387	13	nucleotides	nucleotide	NNS
cord-256444-grw5s2pf	1387	14	at	at	IN
cord-256444-grw5s2pf	1387	15	the	the	DT
cord-256444-grw5s2pf	1387	16	3	3	CD
cord-256444-grw5s2pf	1387	17	'	'	NN
cord-256444-grw5s2pf	1387	18	end	end	NN
cord-256444-grw5s2pf	1387	19	plus	plus	CC
cord-256444-grw5s2pf	1387	20	a	a	DT
cord-256444-grw5s2pf	1387	21	stretch	stretch	NN
cord-256444-grw5s2pf	1387	22	of	of	IN
cord-256444-grw5s2pf	1387	23	poly(A	poly(a	JJ
cord-256444-grw5s2pf	1387	24	)	)	-RRB-
cord-256444-grw5s2pf	1388	1	sequence	sequence	NN
cord-256444-grw5s2pf	1388	2	are	be	VBP
cord-256444-grw5s2pf	1388	3	required	require	VBN
cord-256444-grw5s2pf	1388	4	for	for	IN
cord-256444-grw5s2pf	1388	5	negative	negative	JJ
cord-256444-grw5s2pf	1388	6	-	-	HYPH
cord-256444-grw5s2pf	1388	7	strand	strand	NN
cord-256444-grw5s2pf	1388	8	RNA	RNA	NNP
cord-256444-grw5s2pf	1388	9	synthesis	synthesis	NN
cord-256444-grw5s2pf	1388	10	;	;	:
cord-256444-grw5s2pf	1388	11	no	no	DT
cord-256444-grw5s2pf	1388	12	specific	specific	JJ
cord-256444-grw5s2pf	1388	13	upstream	upstream	JJ
cord-256444-grw5s2pf	1388	14	RNA	RNA	NNP
cord-256444-grw5s2pf	1388	15	sequences	sequence	NNS
cord-256444-grw5s2pf	1388	16	are	be	VBP
cord-256444-grw5s2pf	1388	17	required	require	VBN
cord-256444-grw5s2pf	1388	18	.	.	.
cord-256444-grw5s2pf	1389	1	However	however	RB
cord-256444-grw5s2pf	1389	2	,	,	,
cord-256444-grw5s2pf	1389	3	when	when	WRB
cord-256444-grw5s2pf	1389	4	an	an	DT
cord-256444-grw5s2pf	1389	5	mRNA	mrna	NN
cord-256444-grw5s2pf	1389	6	is	be	VBZ
cord-256444-grw5s2pf	1389	7	transcribed	transcribe	VBN
cord-256444-grw5s2pf	1389	8	from	from	IN
cord-256444-grw5s2pf	1389	9	an	an	DT
cord-256444-grw5s2pf	1389	10	IG	IG	NNP
cord-256444-grw5s2pf	1389	11	site	site	NN
cord-256444-grw5s2pf	1389	12	in	in	IN
cord-256444-grw5s2pf	1389	13	the	the	DT
cord-256444-grw5s2pf	1389	14	same	same	JJ
cord-256444-grw5s2pf	1389	15	DI	DI	NNP
cord-256444-grw5s2pf	1389	16	RNA	RNA	NNP
cord-256444-grw5s2pf	1389	17	,	,	,
cord-256444-grw5s2pf	1389	18	the	the	DT
cord-256444-grw5s2pf	1389	19	negative	negative	JJ
cord-256444-grw5s2pf	1389	20	-	-	HYPH
cord-256444-grw5s2pf	1389	21	strand	strand	NN
cord-256444-grw5s2pf	1389	22	RNA	RNA	NNP
cord-256444-grw5s2pf	1389	23	synthesis	synthesis	NN
cord-256444-grw5s2pf	1389	24	from	from	IN
cord-256444-grw5s2pf	1389	25	this	this	DT
cord-256444-grw5s2pf	1389	26	DI	DI	NNP
cord-256444-grw5s2pf	1389	27	RNA	RNA	NNP
cord-256444-grw5s2pf	1389	28	is	be	VBZ
cord-256444-grw5s2pf	1389	29	inhibited	inhibit	VBN
cord-256444-grw5s2pf	1389	30	,	,	,
cord-256444-grw5s2pf	1389	31	suggesting	suggest	VBG
cord-256444-grw5s2pf	1389	32	a	a	DT
cord-256444-grw5s2pf	1389	33	common	common	JJ
cord-256444-grw5s2pf	1389	34	element	element	NN
cord-256444-grw5s2pf	1389	35	involved	involve	VBN
cord-256444-grw5s2pf	1389	36	in	in	IN
cord-256444-grw5s2pf	1389	37	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1389	38	transcription	transcription	NN
cord-256444-grw5s2pf	1389	39	and	and	CC
cord-256444-grw5s2pf	1389	40	negative	negative	JJ
cord-256444-grw5s2pf	1389	41	-	-	HYPH
cord-256444-grw5s2pf	1389	42	strand	strand	NN
cord-256444-grw5s2pf	1389	43	RNA	RNA	NNP
cord-256444-grw5s2pf	1389	44	synthesis	synthesis	NN
cord-256444-grw5s2pf	1389	45	.	.	.
cord-256444-grw5s2pf	1390	1	One	one	CD
cord-256444-grw5s2pf	1390	2	unanswered	unanswered	JJ
cord-256444-grw5s2pf	1390	3	question	question	NN
cord-256444-grw5s2pf	1390	4	is	be	VBZ
cord-256444-grw5s2pf	1390	5	whether	whether	IN
cord-256444-grw5s2pf	1390	6	or	or	CC
cord-256444-grw5s2pf	1390	7	not	not	RB
cord-256444-grw5s2pf	1390	8	the	the	DT
cord-256444-grw5s2pf	1390	9	sequence	sequence	NN
cord-256444-grw5s2pf	1390	10	requirements	requirement	NNS
cord-256444-grw5s2pf	1390	11	for	for	IN
cord-256444-grw5s2pf	1390	12	the	the	DT
cord-256444-grw5s2pf	1390	13	synthesis	synthesis	NN
cord-256444-grw5s2pf	1390	14	of	of	IN
cord-256444-grw5s2pf	1390	15	genomic	genomic	JJ
cord-256444-grw5s2pf	1390	16	and	and	CC
cord-256444-grw5s2pf	1390	17	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	1390	18	negative	negative	JJ
cord-256444-grw5s2pf	1390	19	-	-	HYPH
cord-256444-grw5s2pf	1390	20	strand	strand	NN
cord-256444-grw5s2pf	1390	21	RNA	RNA	NNP
cord-256444-grw5s2pf	1390	22	are	be	VBP
cord-256444-grw5s2pf	1390	23	identical	identical	JJ
cord-256444-grw5s2pf	1390	24	.	.	.
cord-256444-grw5s2pf	1391	1	3	3	LS
cord-256444-grw5s2pf	1391	2	.	.	.
cord-256444-grw5s2pf	1392	1	Replication	replication	NN
cord-256444-grw5s2pf	1392	2	signal	signal	NN
cord-256444-grw5s2pf	1392	3	.	.	.
cord-256444-grw5s2pf	1393	1	Sequential	sequential	JJ
cord-256444-grw5s2pf	1393	2	deletion	deletion	NN
cord-256444-grw5s2pf	1393	3	analysis	analysis	NN
cord-256444-grw5s2pf	1393	4	has	have	VBZ
cord-256444-grw5s2pf	1393	5	shown	show	VBN
cord-256444-grw5s2pf	1393	6	that	that	IN
cord-256444-grw5s2pf	1393	7	the	the	DT
cord-256444-grw5s2pf	1393	8	replication	replication	NN
cord-256444-grw5s2pf	1393	9	(	(	-LRB-
cord-256444-grw5s2pf	1393	10	i.e.	i.e.	FW
cord-256444-grw5s2pf	1393	11	,	,	,
cord-256444-grw5s2pf	1393	12	complete	complete	JJ
cord-256444-grw5s2pf	1393	13	cycles	cycle	NNS
cord-256444-grw5s2pf	1393	14	of	of	IN
cord-256444-grw5s2pf	1393	15	negative	negative	JJ
cord-256444-grw5s2pf	1393	16	-	-	HYPH
cord-256444-grw5s2pf	1393	17	and	and	CC
cord-256444-grw5s2pf	1393	18	positive	positive	JJ
cord-256444-grw5s2pf	1393	19	-	-	HYPH
cord-256444-grw5s2pf	1393	20	strand	strand	NN
cord-256444-grw5s2pf	1393	21	RNA	RNA	NNP
cord-256444-grw5s2pf	1393	22	synthesis	synthesis	NN
cord-256444-grw5s2pf	1393	23	)	)	-RRB-
cord-256444-grw5s2pf	1393	24	of	of	IN
cord-256444-grw5s2pf	1393	25	MHV	MHV	NNP
cord-256444-grw5s2pf	1393	26	DIssE	DIssE	NNP
cord-256444-grw5s2pf	1393	27	or	or	CC
cord-256444-grw5s2pf	1393	28	DIssF	DIssF	NNP
cord-256444-grw5s2pf	1393	29	RNAs	rna	NNS
cord-256444-grw5s2pf	1393	30	requires	require	VBZ
cord-256444-grw5s2pf	1393	31	approximately	approximately	RB
cord-256444-grw5s2pf	1393	32	400	400	CD
cord-256444-grw5s2pf	1393	33	-	-	SYM
cord-256444-grw5s2pf	1393	34	800	800	CD
cord-256444-grw5s2pf	1393	35	nucleotides	nucleotide	NNS
cord-256444-grw5s2pf	1393	36	from	from	IN
cord-256444-grw5s2pf	1393	37	both	both	CC
cord-256444-grw5s2pf	1393	38	the	the	DT
cord-256444-grw5s2pf	1393	39	5	5	CD
cord-256444-grw5s2pf	1393	40	'	'	''
cord-256444-grw5s2pf	1393	41	and	and	CC
cord-256444-grw5s2pf	1393	42	3	3	CD
cord-256444-grw5s2pf	1393	43	'	'	POS
cord-256444-grw5s2pf	1393	44	ends	end	NNS
cord-256444-grw5s2pf	1393	45	.	.	.
cord-256444-grw5s2pf	1394	1	The	the	DT
cord-256444-grw5s2pf	1394	2	minimum	minimum	JJ
cord-256444-grw5s2pf	1394	3	sequence	sequence	NN
cord-256444-grw5s2pf	1394	4	requirement	requirement	NN
cord-256444-grw5s2pf	1394	5	for	for	IN
cord-256444-grw5s2pf	1394	6	RNA	RNA	NNP
cord-256444-grw5s2pf	1394	7	replication	replication	NN
cord-256444-grw5s2pf	1394	8	may	may	MD
cord-256444-grw5s2pf	1394	9	vary	vary	VB
cord-256444-grw5s2pf	1394	10	with	with	IN
cord-256444-grw5s2pf	1394	11	different	different	JJ
cord-256444-grw5s2pf	1394	12	DI	DI	NNP
cord-256444-grw5s2pf	1394	13	RNAs	rna	NNS
cord-256444-grw5s2pf	1394	14	.	.	.
cord-256444-grw5s2pf	1395	1	These	these	DT
cord-256444-grw5s2pf	1395	2	issues	issue	NNS
cord-256444-grw5s2pf	1395	3	have	have	VBP
cord-256444-grw5s2pf	1395	4	been	be	VBN
cord-256444-grw5s2pf	1395	5	discussed	discuss	VBN
cord-256444-grw5s2pf	1395	6	in	in	IN
cord-256444-grw5s2pf	1395	7	Section	section	NN
cord-256444-grw5s2pf	1395	8	V	v	NN
cord-256444-grw5s2pf	1395	9	,	,	,
cord-256444-grw5s2pf	1395	10	F.	F.	NNP
cord-256444-grw5s2pf	1395	11	4	4	CD
cord-256444-grw5s2pf	1395	12	.	.	.
cord-256444-grw5s2pf	1396	1	Transcriptional	transcriptional	JJ
cord-256444-grw5s2pf	1396	2	signal	signal	NN
cord-256444-grw5s2pf	1396	3	.	.	.
cord-256444-grw5s2pf	1397	1	DI	DI	NNP
cord-256444-grw5s2pf	1397	2	RNAs	rna	NNS
cord-256444-grw5s2pf	1397	3	normally	normally	RB
cord-256444-grw5s2pf	1397	4	do	do	VBP
cord-256444-grw5s2pf	1397	5	not	not	RB
cord-256444-grw5s2pf	1397	6	transcribe	transcribe	VB
cord-256444-grw5s2pf	1397	7	subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	1397	8	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	1397	9	because	because	IN
cord-256444-grw5s2pf	1397	10	they	-PRON-	PRP
cord-256444-grw5s2pf	1397	11	do	do	VBP
cord-256444-grw5s2pf	1397	12	not	not	RB
cord-256444-grw5s2pf	1397	13	have	have	VB
cord-256444-grw5s2pf	1397	14	IG	IG	NNP
cord-256444-grw5s2pf	1397	15	sequences	sequence	NNS
cord-256444-grw5s2pf	1397	16	.	.	.
cord-256444-grw5s2pf	1398	1	Thus	thus	RB
cord-256444-grw5s2pf	1398	2	,	,	,
cord-256444-grw5s2pf	1398	3	natural	natural	JJ
cord-256444-grw5s2pf	1398	4	DI	DI	NNP
cord-256444-grw5s2pf	1398	5	RNAs	rna	NNS
cord-256444-grw5s2pf	1398	6	can	can	MD
cord-256444-grw5s2pf	1398	7	synthesize	synthesize	VB
cord-256444-grw5s2pf	1398	8	only	only	RB
cord-256444-grw5s2pf	1398	9	the	the	DT
cord-256444-grw5s2pf	1398	10	full	full	JJ
cord-256444-grw5s2pf	1398	11	-	-	HYPH
cord-256444-grw5s2pf	1398	12	sized	sized	JJ
cord-256444-grw5s2pf	1398	13	DI	DI	NNP
cord-256444-grw5s2pf	1398	14	RNA	RNA	NNP
cord-256444-grw5s2pf	1398	15	.	.	.
cord-256444-grw5s2pf	1399	1	However	however	RB
cord-256444-grw5s2pf	1399	2	,	,	,
cord-256444-grw5s2pf	1399	3	by	by	IN
cord-256444-grw5s2pf	1399	4	introduction	introduction	NN
cord-256444-grw5s2pf	1399	5	of	of	IN
cord-256444-grw5s2pf	1399	6	the	the	DT
cord-256444-grw5s2pf	1399	7	consensus	consensus	NN
cord-256444-grw5s2pf	1399	8	IG	IG	NNP
cord-256444-grw5s2pf	1399	9	sequences	sequence	NNS
cord-256444-grw5s2pf	1399	10	into	into	IN
cord-256444-grw5s2pf	1399	11	DI	DI	NNP
cord-256444-grw5s2pf	1399	12	RNA	RNA	NNP
cord-256444-grw5s2pf	1400	1	(	(	-LRB-
cord-256444-grw5s2pf	1400	2	Makino	Makino	NNP
cord-256444-grw5s2pf	1400	3	et	et	NNP
cord-256444-grw5s2pf	1400	4	al	al	NNP
cord-256444-grw5s2pf	1400	5	.	.	NNP
cord-256444-grw5s2pf	1400	6	,	,	,
cord-256444-grw5s2pf	1400	7	19911	19911	CD
cord-256444-grw5s2pf	1400	8	,	,	,
cord-256444-grw5s2pf	1400	9	it	-PRON-	PRP
cord-256444-grw5s2pf	1400	10	has	have	VBZ
cord-256444-grw5s2pf	1400	11	been	be	VBN
cord-256444-grw5s2pf	1400	12	possible	possible	JJ
cord-256444-grw5s2pf	1400	13	to	to	TO
cord-256444-grw5s2pf	1400	14	use	use	VB
cord-256444-grw5s2pf	1400	15	DI	DI	NNP
cord-256444-grw5s2pf	1400	16	RNA	RNA	NNP
cord-256444-grw5s2pf	1400	17	as	as	IN
cord-256444-grw5s2pf	1400	18	a	a	DT
cord-256444-grw5s2pf	1400	19	vector	vector	NN
cord-256444-grw5s2pf	1400	20	for	for	IN
cord-256444-grw5s2pf	1400	21	determining	determine	VBG
cord-256444-grw5s2pf	1400	22	the	the	DT
cord-256444-grw5s2pf	1400	23	sequence	sequence	NN
cord-256444-grw5s2pf	1400	24	requirement	requirement	NN
cord-256444-grw5s2pf	1400	25	for	for	IN
cord-256444-grw5s2pf	1400	26	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1400	27	RNA	RNA	NNP
cord-256444-grw5s2pf	1400	28	transcription	transcription	NN
cord-256444-grw5s2pf	1400	29	.	.	.
cord-256444-grw5s2pf	1401	1	The	the	DT
cord-256444-grw5s2pf	1401	2	cis	cis	NNP
cord-256444-grw5s2pf	1401	3	-	-	HYPH
cord-256444-grw5s2pf	1401	4	and	and	CC
cord-256444-grw5s2pf	1401	5	trans	trans	JJ
cord-256444-grw5s2pf	1401	6	-	-	JJ
cord-256444-grw5s2pf	1401	7	acting	acting	JJ
cord-256444-grw5s2pf	1401	8	signals	signal	NNS
cord-256444-grw5s2pf	1401	9	for	for	IN
cord-256444-grw5s2pf	1401	10	transcription	transcription	NN
cord-256444-grw5s2pf	1401	11	have	have	VBP
cord-256444-grw5s2pf	1401	12	been	be	VBN
cord-256444-grw5s2pf	1401	13	described	describe	VBN
cord-256444-grw5s2pf	1401	14	in	in	IN
cord-256444-grw5s2pf	1401	15	Section	section	NN
cord-256444-grw5s2pf	1401	16	V	V	NNP
cord-256444-grw5s2pf	1401	17	,	,	,
cord-256444-grw5s2pf	1401	18	E.	E.	NNP
cord-256444-grw5s2pf	1401	19	5	5	CD
cord-256444-grw5s2pf	1401	20	.	.	.
cord-256444-grw5s2pf	1402	1	Recombination	recombination	NN
cord-256444-grw5s2pf	1402	2	.	.	.
cord-256444-grw5s2pf	1403	1	DI	DI	NNP
cord-256444-grw5s2pf	1403	2	RNAs	rna	NNS
cord-256444-grw5s2pf	1403	3	of	of	IN
cord-256444-grw5s2pf	1403	4	MHV	MHV	NNP
cord-256444-grw5s2pf	1403	5	have	have	VBP
cord-256444-grw5s2pf	1403	6	been	be	VBN
cord-256444-grw5s2pf	1403	7	demonstrated	demonstrate	VBN
cord-256444-grw5s2pf	1403	8	to	to	TO
cord-256444-grw5s2pf	1403	9	undergo	undergo	VB
cord-256444-grw5s2pf	1403	10	a	a	DT
cord-256444-grw5s2pf	1403	11	high	high	JJ
cord-256444-grw5s2pf	1403	12	frequency	frequency	NN
cord-256444-grw5s2pf	1403	13	of	of	IN
cord-256444-grw5s2pf	1403	14	recombination	recombination	NN
cord-256444-grw5s2pf	1403	15	with	with	IN
cord-256444-grw5s2pf	1403	16	helper	helper	NN
cord-256444-grw5s2pf	1403	17	virus	virus	NN
cord-256444-grw5s2pf	1403	18	RNA	RNA	NNP
cord-256444-grw5s2pf	1403	19	.	.	.
cord-256444-grw5s2pf	1404	1	As	as	IN
cord-256444-grw5s2pf	1404	2	discussed	discuss	VBN
cord-256444-grw5s2pf	1404	3	above	above	RB
cord-256444-grw5s2pf	1404	4	,	,	,
cord-256444-grw5s2pf	1404	5	this	this	DT
cord-256444-grw5s2pf	1404	6	accounts	account	VBZ
cord-256444-grw5s2pf	1404	7	for	for	IN
cord-256444-grw5s2pf	1404	8	the	the	DT
cord-256444-grw5s2pf	1404	9	evolution	evolution	NN
cord-256444-grw5s2pf	1404	10	of	of	IN
cord-256444-grw5s2pf	1404	11	MHV	MHV	NNP
cord-256444-grw5s2pf	1404	12	DI	DI	NNP
cord-256444-grw5s2pf	1404	13	RNA	RNA	NNP
cord-256444-grw5s2pf	1404	14	species	specie	NNS
cord-256444-grw5s2pf	1404	15	during	during	IN
cord-256444-grw5s2pf	1404	16	serial	serial	JJ
cord-256444-grw5s2pf	1404	17	passages	passage	NNS
cord-256444-grw5s2pf	1404	18	of	of	IN
cord-256444-grw5s2pf	1404	19	viruses	virus	NNS
cord-256444-grw5s2pf	1404	20	.	.	.
cord-256444-grw5s2pf	1405	1	Furthermore	furthermore	RB
cord-256444-grw5s2pf	1405	2	,	,	,
cord-256444-grw5s2pf	1405	3	MHV	MHV	NNP
cord-256444-grw5s2pf	1405	4	DI	DI	NNP
cord-256444-grw5s2pf	1405	5	RNAs	rna	NNS
cord-256444-grw5s2pf	1405	6	with	with	IN
cord-256444-grw5s2pf	1405	7	a	a	DT
cord-256444-grw5s2pf	1405	8	smaller	small	JJR
cord-256444-grw5s2pf	1405	9	ORF	ORF	NNP
cord-256444-grw5s2pf	1405	10	are	be	VBP
cord-256444-grw5s2pf	1405	11	frequently	frequently	RB
cord-256444-grw5s2pf	1405	12	replaced	replace	VBN
cord-256444-grw5s2pf	1405	13	by	by	IN
cord-256444-grw5s2pf	1405	14	a	a	DT
cord-256444-grw5s2pf	1405	15	DI	DI	NNP
cord-256444-grw5s2pf	1405	16	RNA	RNA	NNP
cord-256444-grw5s2pf	1405	17	with	with	IN
cord-256444-grw5s2pf	1405	18	a	a	DT
cord-256444-grw5s2pf	1405	19	larger	large	JJR
cord-256444-grw5s2pf	1405	20	ORF	ORF	NNP
cord-256444-grw5s2pf	1405	21	by	by	IN
cord-256444-grw5s2pf	1405	22	recombination	recombination	NN
cord-256444-grw5s2pf	1405	23	with	with	IN
cord-256444-grw5s2pf	1405	24	the	the	DT
cord-256444-grw5s2pf	1405	25	helper	helper	NN
cord-256444-grw5s2pf	1405	26	virus	virus	NN
cord-256444-grw5s2pf	1405	27	RNA	RNA	NNP
cord-256444-grw5s2pf	1405	28	(	(	-LRB-
cord-256444-grw5s2pf	1405	29	de	de	FW
cord-256444-grw5s2pf	1405	30	Groot	Groot	NNP
cord-256444-grw5s2pf	1405	31	et	et	FW
cord-256444-grw5s2pf	1405	32	al	al	NNP
cord-256444-grw5s2pf	1405	33	.	.	NNP
cord-256444-grw5s2pf	1405	34	,	,	,
cord-256444-grw5s2pf	1405	35	1992	1992	CD
cord-256444-grw5s2pf	1405	36	;	;	.
cord-256444-grw5s2pf	1406	1	Kim	Kim	NNP
cord-256444-grw5s2pf	1406	2	et	et	NNP
cord-256444-grw5s2pf	1406	3	al	al	NNP
cord-256444-grw5s2pf	1406	4	.	.	.
cord-256444-grw5s2pf	1407	1	,	,	,
cord-256444-grw5s2pf	1407	2	1993a	1993a	CD
cord-256444-grw5s2pf	1407	3	)	)	-RRB-
cord-256444-grw5s2pf	1407	4	,	,	,
cord-256444-grw5s2pf	1407	5	suggesting	suggest	VBG
cord-256444-grw5s2pf	1407	6	that	that	IN
cord-256444-grw5s2pf	1407	7	recombination	recombination	NN
cord-256444-grw5s2pf	1407	8	between	between	IN
cord-256444-grw5s2pf	1407	9	DI	DI	NNP
cord-256444-grw5s2pf	1407	10	RNAs	rna	NNS
cord-256444-grw5s2pf	1407	11	and	and	CC
cord-256444-grw5s2pf	1407	12	helper	helper	NN
cord-256444-grw5s2pf	1407	13	virus	virus	NN
cord-256444-grw5s2pf	1407	14	RNAs	rna	NNS
cord-256444-grw5s2pf	1407	15	occurs	occur	VBZ
cord-256444-grw5s2pf	1407	16	readily	readily	RB
cord-256444-grw5s2pf	1407	17	.	.	.
cord-256444-grw5s2pf	1408	1	The	the	DT
cord-256444-grw5s2pf	1408	2	reciprocal	reciprocal	JJ
cord-256444-grw5s2pf	1408	3	recombination	recombination	NN
cord-256444-grw5s2pf	1408	4	between	between	IN
cord-256444-grw5s2pf	1408	5	DI	DI	NNP
cord-256444-grw5s2pf	1408	6	RNA	RNA	NNP
cord-256444-grw5s2pf	1408	7	and	and	CC
cord-256444-grw5s2pf	1408	8	helper	helper	NN
cord-256444-grw5s2pf	1408	9	virus	virus	NN
cord-256444-grw5s2pf	1408	10	RNA	RNA	NNP
cord-256444-grw5s2pf	1408	11	,	,	,
cord-256444-grw5s2pf	1408	12	i.e.	i.e.	FW
cord-256444-grw5s2pf	1408	13	,	,	,
cord-256444-grw5s2pf	1408	14	the	the	DT
cord-256444-grw5s2pf	1408	15	transfer	transfer	NN
cord-256444-grw5s2pf	1408	16	of	of	IN
cord-256444-grw5s2pf	1408	17	DI	DI	NNP
cord-256444-grw5s2pf	1408	18	RNA	RNA	NNP
cord-256444-grw5s2pf	1408	19	sequences	sequence	NNS
cord-256444-grw5s2pf	1408	20	to	to	IN
cord-256444-grw5s2pf	1408	21	the	the	DT
cord-256444-grw5s2pf	1408	22	helper	helper	NN
cord-256444-grw5s2pf	1408	23	virus	virus	NN
cord-256444-grw5s2pf	1408	24	RNA	RNA	NNP
cord-256444-grw5s2pf	1408	25	,	,	,
cord-256444-grw5s2pf	1408	26	also	also	RB
cord-256444-grw5s2pf	1408	27	has	have	VBZ
cord-256444-grw5s2pf	1408	28	been	be	VBN
cord-256444-grw5s2pf	1408	29	observed	observe	VBN
cord-256444-grw5s2pf	1408	30	.	.	.
cord-256444-grw5s2pf	1409	1	As	as	IN
cord-256444-grw5s2pf	1409	2	a	a	DT
cord-256444-grw5s2pf	1409	3	result	result	NN
cord-256444-grw5s2pf	1409	4	,	,	,
cord-256444-grw5s2pf	1409	5	the	the	DT
cord-256444-grw5s2pf	1409	6	genetic	genetic	JJ
cord-256444-grw5s2pf	1409	7	markers	marker	NNS
cord-256444-grw5s2pf	1409	8	on	on	IN
cord-256444-grw5s2pf	1409	9	the	the	DT
cord-256444-grw5s2pf	1409	10	DI	DI	NNP
cord-256444-grw5s2pf	1409	11	RNA	RNA	NNP
cord-256444-grw5s2pf	1409	12	can	can	MD
cord-256444-grw5s2pf	1409	13	be	be	VB
cord-256444-grw5s2pf	1409	14	incorporated	incorporate	VBN
cord-256444-grw5s2pf	1409	15	into	into	IN
cord-256444-grw5s2pf	1409	16	the	the	DT
cord-256444-grw5s2pf	1409	17	helper	helper	NN
cord-256444-grw5s2pf	1409	18	virus	virus	NN
cord-256444-grw5s2pf	1409	19	RNA	RNA	NNP
cord-256444-grw5s2pf	1409	20	(	(	-LRB-
cord-256444-grw5s2pf	1409	21	Koetzner	Koetzner	NNP
cord-256444-grw5s2pf	1409	22	et	et	NNP
cord-256444-grw5s2pf	1409	23	al	al	NNP
cord-256444-grw5s2pf	1409	24	.	.	NNP
cord-256444-grw5s2pf	1409	25	,	,	,
cord-256444-grw5s2pf	1409	26	1992	1992	CD
cord-256444-grw5s2pf	1409	27	)	)	-RRB-
cord-256444-grw5s2pf	1409	28	.	.	.
cord-256444-grw5s2pf	1410	1	Recombination	recombination	NN
cord-256444-grw5s2pf	1410	2	between	between	IN
cord-256444-grw5s2pf	1410	3	two	two	CD
cord-256444-grw5s2pf	1410	4	DI	DI	NNP
cord-256444-grw5s2pf	1410	5	RNAs	rna	NNS
cord-256444-grw5s2pf	1410	6	,	,	,
cord-256444-grw5s2pf	1410	7	however	however	RB
cord-256444-grw5s2pf	1410	8	,	,	,
cord-256444-grw5s2pf	1410	9	has	have	VBZ
cord-256444-grw5s2pf	1410	10	not	not	RB
cord-256444-grw5s2pf	1410	11	been	be	VBN
cord-256444-grw5s2pf	1410	12	described	describe	VBN
cord-256444-grw5s2pf	1410	13	.	.	.
cord-256444-grw5s2pf	1411	1	Sequence	sequence	NN
cord-256444-grw5s2pf	1411	2	requirements	requirement	NNS
cord-256444-grw5s2pf	1411	3	for	for	IN
cord-256444-grw5s2pf	1411	4	RNA	rna	NN
cord-256444-grw5s2pf	1411	5	recombination	recombination	NN
cord-256444-grw5s2pf	1411	6	also	also	RB
cord-256444-grw5s2pf	1411	7	have	have	VBP
cord-256444-grw5s2pf	1411	8	not	not	RB
cord-256444-grw5s2pf	1411	9	been	be	VBN
cord-256444-grw5s2pf	1411	10	studied	study	VBN
cord-256444-grw5s2pf	1411	11	.	.	.
cord-256444-grw5s2pf	1412	1	BCV	BCV	NNP
cord-256444-grw5s2pf	1412	2	DI	DI	NNP
cord-256444-grw5s2pf	1412	3	RNAs	rna	NNS
cord-256444-grw5s2pf	1412	4	also	also	RB
cord-256444-grw5s2pf	1412	5	undergo	undergo	VBP
cord-256444-grw5s2pf	1412	6	frequent	frequent	JJ
cord-256444-grw5s2pf	1412	7	recombination	recombination	NN
cord-256444-grw5s2pf	1412	8	.	.	.
cord-256444-grw5s2pf	1413	1	However	however	RB
cord-256444-grw5s2pf	1413	2	,	,	,
cord-256444-grw5s2pf	1413	3	DI	DI	NNP
cord-256444-grw5s2pf	1413	4	RNAs	rna	NNS
cord-256444-grw5s2pf	1413	5	of	of	IN
cord-256444-grw5s2pf	1413	6	IBV	IBV	NNP
cord-256444-grw5s2pf	1413	7	and	and	CC
cord-256444-grw5s2pf	1413	8	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1413	9	appear	appear	VBP
cord-256444-grw5s2pf	1413	10	to	to	TO
cord-256444-grw5s2pf	1413	11	be	be	VB
cord-256444-grw5s2pf	1413	12	more	more	RBR
cord-256444-grw5s2pf	1413	13	stable	stable	JJ
cord-256444-grw5s2pf	1413	14	.	.	.
cord-256444-grw5s2pf	1414	1	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1414	2	research	research	NN
cord-256444-grw5s2pf	1414	3	has	have	VBZ
cord-256444-grw5s2pf	1414	4	made	make	VBN
cord-256444-grw5s2pf	1414	5	tremendous	tremendous	JJ
cord-256444-grw5s2pf	1414	6	progress	progress	NN
cord-256444-grw5s2pf	1414	7	in	in	IN
cord-256444-grw5s2pf	1414	8	the	the	DT
cord-256444-grw5s2pf	1414	9	last	last	JJ
cord-256444-grw5s2pf	1414	10	decade	decade	NN
cord-256444-grw5s2pf	1414	11	.	.	.
cord-256444-grw5s2pf	1415	1	The	the	DT
cord-256444-grw5s2pf	1415	2	virus	virus	NN
cord-256444-grw5s2pf	1415	3	family	family	NN
cord-256444-grw5s2pf	1415	4	has	have	VBZ
cord-256444-grw5s2pf	1415	5	grown	grow	VBN
cord-256444-grw5s2pf	1415	6	in	in	IN
cord-256444-grw5s2pf	1415	7	size	size	NN
cord-256444-grw5s2pf	1415	8	,	,	,
cord-256444-grw5s2pf	1415	9	and	and	CC
cord-256444-grw5s2pf	1415	10	many	many	JJ
cord-256444-grw5s2pf	1415	11	of	of	IN
cord-256444-grw5s2pf	1415	12	the	the	DT
cord-256444-grw5s2pf	1415	13	features	feature	NNS
cord-256444-grw5s2pf	1415	14	thought	think	VBN
cord-256444-grw5s2pf	1415	15	to	to	TO
cord-256444-grw5s2pf	1415	16	be	be	VB
cord-256444-grw5s2pf	1415	17	unique	unique	JJ
cord-256444-grw5s2pf	1415	18	to	to	IN
cord-256444-grw5s2pf	1415	19	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1415	20	have	have	VBP
cord-256444-grw5s2pf	1415	21	now	now	RB
cord-256444-grw5s2pf	1415	22	been	be	VBN
cord-256444-grw5s2pf	1415	23	found	find	VBN
cord-256444-grw5s2pf	1415	24	to	to	TO
cord-256444-grw5s2pf	1415	25	be	be	VB
cord-256444-grw5s2pf	1415	26	shared	share	VBN
cord-256444-grw5s2pf	1415	27	by	by	IN
cord-256444-grw5s2pf	1415	28	some	some	DT
cord-256444-grw5s2pf	1415	29	other	other	JJ
cord-256444-grw5s2pf	1415	30	viruses	virus	NNS
cord-256444-grw5s2pf	1415	31	.	.	.
cord-256444-grw5s2pf	1416	1	Since	since	IN
cord-256444-grw5s2pf	1416	2	the	the	DT
cord-256444-grw5s2pf	1416	3	last	last	JJ
cord-256444-grw5s2pf	1416	4	time	time	NN
cord-256444-grw5s2pf	1416	5	this	this	DT
cord-256444-grw5s2pf	1416	6	serial	serial	JJ
cord-256444-grw5s2pf	1416	7	publication	publication	NN
cord-256444-grw5s2pf	1416	8	published	publish	VBD
cord-256444-grw5s2pf	1416	9	the	the	DT
cord-256444-grw5s2pf	1416	10	first	first	JJ
cord-256444-grw5s2pf	1416	11	comprehensive	comprehensive	JJ
cord-256444-grw5s2pf	1416	12	review	review	NN
cord-256444-grw5s2pf	1416	13	of	of	IN
cord-256444-grw5s2pf	1416	14	the	the	DT
cord-256444-grw5s2pf	1416	15	molecular	molecular	JJ
cord-256444-grw5s2pf	1416	16	biology	biology	NN
cord-256444-grw5s2pf	1416	17	of	of	IN
cord-256444-grw5s2pf	1416	18	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1416	19	(	(	-LRB-
cord-256444-grw5s2pf	1416	20	Sturman	Sturman	NNP
cord-256444-grw5s2pf	1416	21	and	and	CC
cord-256444-grw5s2pf	1416	22	Holmes	Holmes	NNP
cord-256444-grw5s2pf	1416	23	,	,	,
cord-256444-grw5s2pf	1416	24	1983	1983	CD
cord-256444-grw5s2pf	1416	25	)	)	-RRB-
cord-256444-grw5s2pf	1416	26	,	,	,
cord-256444-grw5s2pf	1416	27	the	the	DT
cord-256444-grw5s2pf	1416	28	literature	literature	NN
cord-256444-grw5s2pf	1416	29	on	on	IN
cord-256444-grw5s2pf	1416	30	this	this	DT
cord-256444-grw5s2pf	1416	31	virus	virus	NN
cord-256444-grw5s2pf	1416	32	has	have	VBZ
cord-256444-grw5s2pf	1416	33	grown	grow	VBN
cord-256444-grw5s2pf	1416	34	to	to	TO
cord-256444-grw5s2pf	1416	35	exceed	exceed	VB
cord-256444-grw5s2pf	1416	36	anyone	anyone	NN
cord-256444-grw5s2pf	1416	37	's	's	POS
cord-256444-grw5s2pf	1416	38	ability	ability	NN
cord-256444-grw5s2pf	1416	39	to	to	TO
cord-256444-grw5s2pf	1416	40	do	do	VB
cord-256444-grw5s2pf	1416	41	a	a	DT
cord-256444-grw5s2pf	1416	42	comprehensive	comprehensive	JJ
cord-256444-grw5s2pf	1416	43	review	review	NN
cord-256444-grw5s2pf	1416	44	of	of	IN
cord-256444-grw5s2pf	1416	45	every	every	DT
cord-256444-grw5s2pf	1416	46	topic	topic	NN
cord-256444-grw5s2pf	1416	47	relating	relate	VBG
cord-256444-grw5s2pf	1416	48	to	to	IN
cord-256444-grw5s2pf	1416	49	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1416	50	.	.	.
cord-256444-grw5s2pf	1417	1	In	in	IN
cord-256444-grw5s2pf	1417	2	this	this	DT
cord-256444-grw5s2pf	1417	3	review	review	NN
cord-256444-grw5s2pf	1417	4	,	,	,
cord-256444-grw5s2pf	1417	5	we	-PRON-	PRP
cord-256444-grw5s2pf	1417	6	have	have	VBP
cord-256444-grw5s2pf	1417	7	concentrated	concentrate	VBN
cord-256444-grw5s2pf	1417	8	on	on	IN
cord-256444-grw5s2pf	1417	9	areas	area	NNS
cord-256444-grw5s2pf	1417	10	which	which	WDT
cord-256444-grw5s2pf	1417	11	have	have	VBP
cord-256444-grw5s2pf	1417	12	shown	show	VBN
cord-256444-grw5s2pf	1417	13	the	the	DT
cord-256444-grw5s2pf	1417	14	most	most	JJS
cord-256444-grw5s2pf	1417	15	progress	progress	NN
cord-256444-grw5s2pf	1417	16	and	and	CC
cord-256444-grw5s2pf	1417	17	which	which	WDT
cord-256444-grw5s2pf	1417	18	present	present	VBP
cord-256444-grw5s2pf	1417	19	the	the	DT
cord-256444-grw5s2pf	1417	20	most	most	JJS
cord-256444-grw5s2pf	1417	21	challenges	challenge	NNS
cord-256444-grw5s2pf	1417	22	.	.	.
cord-256444-grw5s2pf	1418	1	Our	-PRON-	PRP$
cord-256444-grw5s2pf	1418	2	choice	choice	NN
cord-256444-grw5s2pf	1418	3	of	of	IN
cord-256444-grw5s2pf	1418	4	literature	literature	NN
cord-256444-grw5s2pf	1418	5	was	be	VBD
cord-256444-grw5s2pf	1418	6	meant	mean	VBN
cord-256444-grw5s2pf	1418	7	to	to	TO
cord-256444-grw5s2pf	1418	8	be	be	VB
cord-256444-grw5s2pf	1418	9	representative	representative	JJ
cord-256444-grw5s2pf	1418	10	but	but	CC
cord-256444-grw5s2pf	1418	11	is	be	VBZ
cord-256444-grw5s2pf	1418	12	by	by	IN
cord-256444-grw5s2pf	1418	13	no	no	DT
cord-256444-grw5s2pf	1418	14	means	means	NN
cord-256444-grw5s2pf	1418	15	comprehensive	comprehensive	JJ
cord-256444-grw5s2pf	1418	16	.	.	.
cord-256444-grw5s2pf	1419	1	Notably	notably	RB
cord-256444-grw5s2pf	1419	2	missing	miss	VBG
cord-256444-grw5s2pf	1419	3	from	from	IN
cord-256444-grw5s2pf	1419	4	this	this	DT
cord-256444-grw5s2pf	1419	5	review	review	NN
cord-256444-grw5s2pf	1419	6	are	be	VBP
cord-256444-grw5s2pf	1419	7	the	the	DT
cord-256444-grw5s2pf	1419	8	molecular	molecular	JJ
cord-256444-grw5s2pf	1419	9	studies	study	NNS
cord-256444-grw5s2pf	1419	10	related	relate	VBN
cord-256444-grw5s2pf	1419	11	to	to	IN
cord-256444-grw5s2pf	1419	12	viral	viral	JJ
cord-256444-grw5s2pf	1419	13	pathogenesis	pathogenesis	NN
cord-256444-grw5s2pf	1419	14	and	and	CC
cord-256444-grw5s2pf	1419	15	the	the	DT
cord-256444-grw5s2pf	1419	16	interactions	interaction	NNS
cord-256444-grw5s2pf	1419	17	between	between	IN
cord-256444-grw5s2pf	1419	18	the	the	DT
cord-256444-grw5s2pf	1419	19	virus	virus	NN
cord-256444-grw5s2pf	1419	20	and	and	CC
cord-256444-grw5s2pf	1419	21	cells	cell	NNS
cord-256444-grw5s2pf	1419	22	.	.	.
cord-256444-grw5s2pf	1420	1	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1420	2	research	research	NN
cord-256444-grw5s2pf	1420	3	has	have	VBZ
cord-256444-grw5s2pf	1420	4	contributed	contribute	VBN
cord-256444-grw5s2pf	1420	5	to	to	IN
cord-256444-grw5s2pf	1420	6	the	the	DT
cord-256444-grw5s2pf	1420	7	understanding	understanding	NN
cord-256444-grw5s2pf	1420	8	of	of	IN
cord-256444-grw5s2pf	1420	9	many	many	JJ
cord-256444-grw5s2pf	1420	10	aspects	aspect	NNS
cord-256444-grw5s2pf	1420	11	of	of	IN
cord-256444-grw5s2pf	1420	12	molecular	molecular	JJ
cord-256444-grw5s2pf	1420	13	biology	biology	NN
cord-256444-grw5s2pf	1420	14	in	in	IN
cord-256444-grw5s2pf	1420	15	general	general	JJ
cord-256444-grw5s2pf	1420	16	,	,	,
cord-256444-grw5s2pf	1420	17	such	such	JJ
cord-256444-grw5s2pf	1420	18	as	as	IN
cord-256444-grw5s2pf	1420	19	the	the	DT
cord-256444-grw5s2pf	1420	20	mechanism	mechanism	NN
cord-256444-grw5s2pf	1420	21	of	of	IN
cord-256444-grw5s2pf	1420	22	RNA	RNA	NNP
cord-256444-grw5s2pf	1420	23	synthesis	synthesis	NN
cord-256444-grw5s2pf	1420	24	,	,	,
cord-256444-grw5s2pf	1420	25	translational	translational	JJ
cord-256444-grw5s2pf	1420	26	control	control	NN
cord-256444-grw5s2pf	1420	27	,	,	,
cord-256444-grw5s2pf	1420	28	and	and	CC
cord-256444-grw5s2pf	1420	29	protein	protein	NN
cord-256444-grw5s2pf	1420	30	transport	transport	NN
cord-256444-grw5s2pf	1420	31	and	and	CC
cord-256444-grw5s2pf	1420	32	processing	processing	NN
cord-256444-grw5s2pf	1420	33	.	.	.
cord-256444-grw5s2pf	1421	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1421	2	remains	remain	VBZ
cord-256444-grw5s2pf	1421	3	a	a	DT
cord-256444-grw5s2pf	1421	4	treasure	treasure	NN
cord-256444-grw5s2pf	1421	5	capable	capable	JJ
cord-256444-grw5s2pf	1421	6	of	of	IN
cord-256444-grw5s2pf	1421	7	generating	generate	VBG
cord-256444-grw5s2pf	1421	8	unexpected	unexpected	JJ
cord-256444-grw5s2pf	1421	9	insights	insight	NNS
cord-256444-grw5s2pf	1421	10	.	.	.
cord-256444-grw5s2pf	1422	1	Despite	despite	IN
cord-256444-grw5s2pf	1422	2	two	two	CD
cord-256444-grw5s2pf	1422	3	decades	decade	NNS
cord-256444-grw5s2pf	1422	4	of	of	IN
cord-256444-grw5s2pf	1422	5	studies	study	NNS
cord-256444-grw5s2pf	1422	6	on	on	IN
cord-256444-grw5s2pf	1422	7	the	the	DT
cord-256444-grw5s2pf	1422	8	molecular	molecular	JJ
cord-256444-grw5s2pf	1422	9	biology	biology	NN
cord-256444-grw5s2pf	1422	10	of	of	IN
cord-256444-grw5s2pf	1422	11	this	this	DT
cord-256444-grw5s2pf	1422	12	virus	virus	NN
cord-256444-grw5s2pf	1422	13	,	,	,
cord-256444-grw5s2pf	1422	14	there	there	EX
cord-256444-grw5s2pf	1422	15	are	be	VBP
cord-256444-grw5s2pf	1422	16	still	still	RB
cord-256444-grw5s2pf	1422	17	many	many	JJ
cord-256444-grw5s2pf	1422	18	problems	problem	NNS
cord-256444-grw5s2pf	1422	19	to	to	TO
cord-256444-grw5s2pf	1422	20	be	be	VB
cord-256444-grw5s2pf	1422	21	solved	solve	VBN
cord-256444-grw5s2pf	1422	22	:	:	:
cord-256444-grw5s2pf	1423	1	1	1	LS
cord-256444-grw5s2pf	1423	2	.	.	.
cord-256444-grw5s2pf	1424	1	With	with	IN
cord-256444-grw5s2pf	1424	2	regard	regard	NN
cord-256444-grw5s2pf	1424	3	to	to	IN
cord-256444-grw5s2pf	1424	4	the	the	DT
cord-256444-grw5s2pf	1424	5	mechanism	mechanism	NN
cord-256444-grw5s2pf	1424	6	of	of	IN
cord-256444-grw5s2pf	1424	7	RNA	RNA	NNP
cord-256444-grw5s2pf	1424	8	transcription	transcription	NN
cord-256444-grw5s2pf	1424	9	,	,	,
cord-256444-grw5s2pf	1424	10	many	many	JJ
cord-256444-grw5s2pf	1424	11	conflicting	conflict	VBG
cord-256444-grw5s2pf	1424	12	data	datum	NNS
cord-256444-grw5s2pf	1424	13	remain	remain	VBP
cord-256444-grw5s2pf	1424	14	.	.	.
cord-256444-grw5s2pf	1425	1	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1425	2	undoubtedly	undoubtedly	RB
cord-256444-grw5s2pf	1425	3	utilizes	utilize	VBZ
cord-256444-grw5s2pf	1425	4	a	a	DT
cord-256444-grw5s2pf	1425	5	unique	unique	JJ
cord-256444-grw5s2pf	1425	6	,	,	,
cord-256444-grw5s2pf	1425	7	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	1425	8	transcription	transcription	NN
cord-256444-grw5s2pf	1425	9	mechanism	mechanism	NN
cord-256444-grw5s2pf	1425	10	,	,	,
cord-256444-grw5s2pf	1425	11	but	but	CC
cord-256444-grw5s2pf	1425	12	how	how	WRB
cord-256444-grw5s2pf	1425	13	it	-PRON-	PRP
cord-256444-grw5s2pf	1425	14	acts	act	VBZ
cord-256444-grw5s2pf	1425	15	is	be	VBZ
cord-256444-grw5s2pf	1425	16	a	a	DT
cord-256444-grw5s2pf	1425	17	subject	subject	NN
cord-256444-grw5s2pf	1425	18	of	of	IN
cord-256444-grw5s2pf	1425	19	debate	debate	NN
cord-256444-grw5s2pf	1425	20	.	.	.
cord-256444-grw5s2pf	1426	1	An	an	DT
cord-256444-grw5s2pf	1426	2	in	in	IN
cord-256444-grw5s2pf	1426	3	uitro	uitro	NNP
cord-256444-grw5s2pf	1426	4	RNA	RNA	NNP
cord-256444-grw5s2pf	1426	5	transcription	transcription	NN
cord-256444-grw5s2pf	1426	6	system	system	NN
cord-256444-grw5s2pf	1426	7	,	,	,
cord-256444-grw5s2pf	1426	8	so	so	RB
cord-256444-grw5s2pf	1426	9	necessary	necessary	JJ
cord-256444-grw5s2pf	1426	10	for	for	IN
cord-256444-grw5s2pf	1426	11	an	an	DT
cord-256444-grw5s2pf	1426	12	understanding	understanding	NN
cord-256444-grw5s2pf	1426	13	of	of	IN
cord-256444-grw5s2pf	1426	14	RNA	RNA	NNP
cord-256444-grw5s2pf	1426	15	synthesis	synthesis	NN
cord-256444-grw5s2pf	1426	16	,	,	,
cord-256444-grw5s2pf	1426	17	is	be	VBZ
cord-256444-grw5s2pf	1426	18	still	still	RB
cord-256444-grw5s2pf	1426	19	in	in	IN
cord-256444-grw5s2pf	1426	20	its	-PRON-	PRP$
cord-256444-grw5s2pf	1426	21	infancy	infancy	NN
cord-256444-grw5s2pf	1426	22	.	.	.
cord-256444-grw5s2pf	1427	1	Related	relate	VBN
cord-256444-grw5s2pf	1427	2	to	to	IN
cord-256444-grw5s2pf	1427	3	this	this	DT
cord-256444-grw5s2pf	1427	4	question	question	NN
cord-256444-grw5s2pf	1427	5	is	be	VBZ
cord-256444-grw5s2pf	1427	6	the	the	DT
cord-256444-grw5s2pf	1427	7	nature	nature	NN
cord-256444-grw5s2pf	1427	8	of	of	IN
cord-256444-grw5s2pf	1427	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1427	10	polymerase	polymerase	NN
cord-256444-grw5s2pf	1427	11	.	.	.
cord-256444-grw5s2pf	1428	1	The	the	DT
cord-256444-grw5s2pf	1428	2	sheer	sheer	JJ
cord-256444-grw5s2pf	1428	3	size	size	NN
cord-256444-grw5s2pf	1428	4	of	of	IN
cord-256444-grw5s2pf	1428	5	the	the	DT
cord-256444-grw5s2pf	1428	6	polymerase	polymerase	NN
cord-256444-grw5s2pf	1428	7	gene	gene	NN
cord-256444-grw5s2pf	1428	8	presents	present	VBZ
cord-256444-grw5s2pf	1428	9	a	a	DT
cord-256444-grw5s2pf	1428	10	daunting	daunting	JJ
cord-256444-grw5s2pf	1428	11	task	task	NN
cord-256444-grw5s2pf	1428	12	.	.	.
cord-256444-grw5s2pf	1429	1	The	the	DT
cord-256444-grw5s2pf	1429	2	availability	availability	NN
cord-256444-grw5s2pf	1429	3	of	of	IN
cord-256444-grw5s2pf	1429	4	the	the	DT
cord-256444-grw5s2pf	1429	5	cDNA	cdna	NN
cord-256444-grw5s2pf	1429	6	clones	clone	NNS
cord-256444-grw5s2pf	1429	7	and	and	CC
cord-256444-grw5s2pf	1429	8	expression	expression	NN
cord-256444-grw5s2pf	1429	9	vectors	vector	NNS
cord-256444-grw5s2pf	1429	10	for	for	IN
cord-256444-grw5s2pf	1429	11	this	this	DT
cord-256444-grw5s2pf	1429	12	gene	gene	NN
cord-256444-grw5s2pf	1429	13	has	have	VBZ
cord-256444-grw5s2pf	1429	14	just	just	RB
cord-256444-grw5s2pf	1429	15	begun	begin	VBN
cord-256444-grw5s2pf	1429	16	to	to	TO
cord-256444-grw5s2pf	1429	17	allow	allow	VB
cord-256444-grw5s2pf	1429	18	this	this	DT
cord-256444-grw5s2pf	1429	19	black	black	JJ
cord-256444-grw5s2pf	1429	20	box	box	NN
cord-256444-grw5s2pf	1429	21	to	to	TO
cord-256444-grw5s2pf	1429	22	be	be	VB
cord-256444-grw5s2pf	1429	23	cracked	crack	VBN
cord-256444-grw5s2pf	1429	24	open	open	JJ
cord-256444-grw5s2pf	1429	25	.	.	.
cord-256444-grw5s2pf	1430	1	This	this	DT
cord-256444-grw5s2pf	1430	2	will	will	MD
cord-256444-grw5s2pf	1430	3	undoubtedly	undoubtedly	RB
cord-256444-grw5s2pf	1430	4	be	be	VB
cord-256444-grw5s2pf	1430	5	a	a	DT
cord-256444-grw5s2pf	1430	6	fruitful	fruitful	JJ
cord-256444-grw5s2pf	1430	7	area	area	NN
cord-256444-grw5s2pf	1430	8	of	of	IN
cord-256444-grw5s2pf	1430	9	future	future	JJ
cord-256444-grw5s2pf	1430	10	research	research	NN
cord-256444-grw5s2pf	1430	11	.	.	.
cord-256444-grw5s2pf	1431	1	2	2	LS
cord-256444-grw5s2pf	1431	2	.	.	.
cord-256444-grw5s2pf	1432	1	The	the	DT
cord-256444-grw5s2pf	1432	2	last	last	JJ
cord-256444-grw5s2pf	1432	3	two	two	CD
cord-256444-grw5s2pf	1432	4	years	year	NNS
cord-256444-grw5s2pf	1432	5	have	have	VBP
cord-256444-grw5s2pf	1432	6	seen	see	VBN
cord-256444-grw5s2pf	1432	7	the	the	DT
cord-256444-grw5s2pf	1432	8	unraveling	unraveling	NN
cord-256444-grw5s2pf	1432	9	of	of	IN
cord-256444-grw5s2pf	1432	10	the	the	DT
cord-256444-grw5s2pf	1432	11	mechanism	mechanism	NN
cord-256444-grw5s2pf	1432	12	of	of	IN
cord-256444-grw5s2pf	1432	13	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1432	14	assembly	assembly	NN
cord-256444-grw5s2pf	1432	15	,	,	,
cord-256444-grw5s2pf	1432	16	which	which	WDT
cord-256444-grw5s2pf	1432	17	,	,	,
cord-256444-grw5s2pf	1432	18	as	as	IN
cord-256444-grw5s2pf	1432	19	it	-PRON-	PRP
cord-256444-grw5s2pf	1432	20	turns	turn	VBZ
cord-256444-grw5s2pf	1432	21	out	out	RP
cord-256444-grw5s2pf	1432	22	,	,	,
cord-256444-grw5s2pf	1432	23	involves	involve	VBZ
cord-256444-grw5s2pf	1432	24	a	a	DT
cord-256444-grw5s2pf	1432	25	littlecharacterized	littlecharacterized	JJ
cord-256444-grw5s2pf	1432	26	E	e	NN
cord-256444-grw5s2pf	1432	27	protein	protein	NN
cord-256444-grw5s2pf	1432	28	.	.	.
cord-256444-grw5s2pf	1433	1	How	how	WRB
cord-256444-grw5s2pf	1433	2	the	the	DT
cord-256444-grw5s2pf	1433	3	various	various	JJ
cord-256444-grw5s2pf	1433	4	viral	viral	JJ
cord-256444-grw5s2pf	1433	5	structural	structural	JJ
cord-256444-grw5s2pf	1433	6	proteins	protein	NNS
cord-256444-grw5s2pf	1433	7	interact	interact	VBP
cord-256444-grw5s2pf	1433	8	with	with	IN
cord-256444-grw5s2pf	1433	9	each	each	DT
cord-256444-grw5s2pf	1433	10	other	other	JJ
cord-256444-grw5s2pf	1433	11	in	in	IN
cord-256444-grw5s2pf	1433	12	the	the	DT
cord-256444-grw5s2pf	1433	13	various	various	JJ
cord-256444-grw5s2pf	1433	14	subcellular	subcellular	JJ
cord-256444-grw5s2pf	1433	15	compartments	compartment	NNS
cord-256444-grw5s2pf	1433	16	to	to	TO
cord-256444-grw5s2pf	1433	17	form	form	VB
cord-256444-grw5s2pf	1433	18	a	a	DT
cord-256444-grw5s2pf	1433	19	complete	complete	JJ
cord-256444-grw5s2pf	1433	20	virus	virus	NN
cord-256444-grw5s2pf	1433	21	particle	particle	NN
cord-256444-grw5s2pf	1433	22	is	be	VBZ
cord-256444-grw5s2pf	1433	23	an	an	DT
cord-256444-grw5s2pf	1433	24	exciting	exciting	JJ
cord-256444-grw5s2pf	1433	25	frontier	frontier	NN
cord-256444-grw5s2pf	1433	26	.	.	.
cord-256444-grw5s2pf	1434	1	3	3	LS
cord-256444-grw5s2pf	1434	2	.	.	.
cord-256444-grw5s2pf	1435	1	After	after	IN
cord-256444-grw5s2pf	1435	2	more	more	JJR
cord-256444-grw5s2pf	1435	3	than	than	IN
cord-256444-grw5s2pf	1435	4	30	30	CD
cord-256444-grw5s2pf	1435	5	years	year	NNS
cord-256444-grw5s2pf	1435	6	since	since	IN
cord-256444-grw5s2pf	1435	7	the	the	DT
cord-256444-grw5s2pf	1435	8	first	first	JJ
cord-256444-grw5s2pf	1435	9	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1435	10	was	be	VBD
cord-256444-grw5s2pf	1435	11	seen	see	VBN
cord-256444-grw5s2pf	1435	12	under	under	IN
cord-256444-grw5s2pf	1435	13	electron	electron	NN
cord-256444-grw5s2pf	1435	14	microscope	microscope	NN
cord-256444-grw5s2pf	1435	15	,	,	,
cord-256444-grw5s2pf	1435	16	an	an	DT
cord-256444-grw5s2pf	1435	17	unexpected	unexpected	JJ
cord-256444-grw5s2pf	1435	18	new	new	JJ
cord-256444-grw5s2pf	1435	19	feature	feature	NN
cord-256444-grw5s2pf	1435	20	of	of	IN
cord-256444-grw5s2pf	1435	21	the	the	DT
cord-256444-grw5s2pf	1435	22	virus	virus	NN
cord-256444-grw5s2pf	1435	23	,	,	,
cord-256444-grw5s2pf	1435	24	namely	namely	RB
cord-256444-grw5s2pf	1435	25	,	,	,
cord-256444-grw5s2pf	1435	26	an	an	DT
cord-256444-grw5s2pf	1435	27	icosahedral	icosahedral	JJ
cord-256444-grw5s2pf	1435	28	core	core	NN
cord-256444-grw5s2pf	1435	29	with	with	IN
cord-256444-grw5s2pf	1435	30	a	a	DT
cord-256444-grw5s2pf	1435	31	helical	helical	JJ
cord-256444-grw5s2pf	1435	32	nucleoprotein	nucleoprotein	NN
cord-256444-grw5s2pf	1435	33	,	,	,
cord-256444-grw5s2pf	1435	34	was	be	VBD
cord-256444-grw5s2pf	1435	35	recently	recently	RB
cord-256444-grw5s2pf	1435	36	uncovered	uncover	VBN
cord-256444-grw5s2pf	1435	37	.	.	.
cord-256444-grw5s2pf	1436	1	This	this	DT
cord-256444-grw5s2pf	1436	2	structure	structure	NN
cord-256444-grw5s2pf	1436	3	places	place	VBZ
cord-256444-grw5s2pf	1436	4	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1436	5	in	in	IN
cord-256444-grw5s2pf	1436	6	a	a	DT
cord-256444-grw5s2pf	1436	7	unique	unique	JJ
cord-256444-grw5s2pf	1436	8	position	position	NN
cord-256444-grw5s2pf	1436	9	among	among	IN
cord-256444-grw5s2pf	1436	10	RNA	RNA	NNP
cord-256444-grw5s2pf	1436	11	viruses	virus	NNS
cord-256444-grw5s2pf	1436	12	because	because	IN
cord-256444-grw5s2pf	1436	13	it	-PRON-	PRP
cord-256444-grw5s2pf	1436	14	takes	take	VBZ
cord-256444-grw5s2pf	1436	15	on	on	RP
cord-256444-grw5s2pf	1436	16	the	the	DT
cord-256444-grw5s2pf	1436	17	characteristics	characteristic	NNS
cord-256444-grw5s2pf	1436	18	of	of	IN
cord-256444-grw5s2pf	1436	19	positive-	positive-	JJ
cord-256444-grw5s2pf	1436	20	,	,	,
cord-256444-grw5s2pf	1436	21	negative	negative	JJ
cord-256444-grw5s2pf	1436	22	-	-	:
cord-256444-grw5s2pf	1436	23	and	and	CC
cord-256444-grw5s2pf	1436	24	double	double	JJ
cord-256444-grw5s2pf	1436	25	-	-	HYPH
cord-256444-grw5s2pf	1436	26	strand	strand	NN
cord-256444-grw5s2pf	1436	27	RNA	RNA	NNP
cord-256444-grw5s2pf	1436	28	viruses	virus	NNS
cord-256444-grw5s2pf	1436	29	in	in	IN
cord-256444-grw5s2pf	1436	30	morphology	morphology	NN
cord-256444-grw5s2pf	1436	31	.	.	.
cord-256444-grw5s2pf	1437	1	This	this	DT
cord-256444-grw5s2pf	1437	2	recent	recent	JJ
cord-256444-grw5s2pf	1437	3	finding	finding	NN
cord-256444-grw5s2pf	1437	4	challenges	challenge	VBZ
cord-256444-grw5s2pf	1437	5	us	-PRON-	PRP
cord-256444-grw5s2pf	1437	6	to	to	TO
cord-256444-grw5s2pf	1437	7	reevaluate	reevaluate	VB
cord-256444-grw5s2pf	1437	8	the	the	DT
cord-256444-grw5s2pf	1437	9	structure	structure	NN
cord-256444-grw5s2pf	1437	10	of	of	IN
cord-256444-grw5s2pf	1437	11	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1437	12	.	.	.
cord-256444-grw5s2pf	1438	1	4	4	LS
cord-256444-grw5s2pf	1438	2	.	.	.
cord-256444-grw5s2pf	1439	1	The	the	DT
cord-256444-grw5s2pf	1439	2	ability	ability	NN
cord-256444-grw5s2pf	1439	3	to	to	TO
cord-256444-grw5s2pf	1439	4	perform	perform	VB
cord-256444-grw5s2pf	1439	5	reverse	reverse	JJ
cord-256444-grw5s2pf	1439	6	genetic	genetic	JJ
cord-256444-grw5s2pf	1439	7	studies	study	NNS
cord-256444-grw5s2pf	1439	8	of	of	IN
cord-256444-grw5s2pf	1439	9	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1439	10	is	be	VBZ
cord-256444-grw5s2pf	1439	11	still	still	RB
cord-256444-grw5s2pf	1439	12	very	very	RB
cord-256444-grw5s2pf	1439	13	limited	limited	JJ
cord-256444-grw5s2pf	1439	14	.	.	.
cord-256444-grw5s2pf	1440	1	Expression	expression	NN
cord-256444-grw5s2pf	1440	2	of	of	IN
cord-256444-grw5s2pf	1440	3	individual	individual	JJ
cord-256444-grw5s2pf	1440	4	viral	viral	JJ
cord-256444-grw5s2pf	1440	5	genes	gene	NNS
cord-256444-grw5s2pf	1440	6	and	and	CC
cord-256444-grw5s2pf	1440	7	targeted	target	VBN
cord-256444-grw5s2pf	1440	8	recombination	recombination	NN
cord-256444-grw5s2pf	1440	9	of	of	IN
cord-256444-grw5s2pf	1440	10	very	very	RB
cord-256444-grw5s2pf	1440	11	limited	limited	JJ
cord-256444-grw5s2pf	1440	12	RNA	RNA	NNP
cord-256444-grw5s2pf	1440	13	regions	region	NNS
cord-256444-grw5s2pf	1440	14	are	be	VBP
cord-256444-grw5s2pf	1440	15	the	the	DT
cord-256444-grw5s2pf	1440	16	only	only	JJ
cord-256444-grw5s2pf	1440	17	available	available	JJ
cord-256444-grw5s2pf	1440	18	genetic	genetic	JJ
cord-256444-grw5s2pf	1440	19	means	mean	NNS
cord-256444-grw5s2pf	1440	20	for	for	IN
cord-256444-grw5s2pf	1440	21	examining	examine	VBG
cord-256444-grw5s2pf	1440	22	the	the	DT
cord-256444-grw5s2pf	1440	23	structure	structure	NN
cord-256444-grw5s2pf	1440	24	and	and	CC
cord-256444-grw5s2pf	1440	25	function	function	NN
cord-256444-grw5s2pf	1440	26	of	of	IN
cord-256444-grw5s2pf	1440	27	the	the	DT
cord-256444-grw5s2pf	1440	28	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1440	29	genome	genome	NN
cord-256444-grw5s2pf	1440	30	.	.	.
cord-256444-grw5s2pf	1441	1	Perhaps	perhaps	RB
cord-256444-grw5s2pf	1441	2	it	-PRON-	PRP
cord-256444-grw5s2pf	1441	3	is	be	VBZ
cord-256444-grw5s2pf	1441	4	an	an	DT
cord-256444-grw5s2pf	1441	5	unrealistic	unrealistic	JJ
cord-256444-grw5s2pf	1441	6	dream	dream	NN
cord-256444-grw5s2pf	1441	7	,	,	,
cord-256444-grw5s2pf	1441	8	but	but	CC
cord-256444-grw5s2pf	1441	9	progress	progress	NN
cord-256444-grw5s2pf	1441	10	in	in	IN
cord-256444-grw5s2pf	1441	11	polymerase	polymerase	NN
cord-256444-grw5s2pf	1441	12	chain	chain	NN
cord-256444-grw5s2pf	1441	13	reaction	reaction	NN
cord-256444-grw5s2pf	1441	14	technology	technology	NN
cord-256444-grw5s2pf	1441	15	may	may	MD
cord-256444-grw5s2pf	1441	16	one	one	CD
cord-256444-grw5s2pf	1441	17	day	day	NN
cord-256444-grw5s2pf	1441	18	allow	allow	VB
cord-256444-grw5s2pf	1441	19	an	an	DT
cord-256444-grw5s2pf	1441	20	infectious	infectious	JJ
cord-256444-grw5s2pf	1441	21	cDNA	cdna	NN
cord-256444-grw5s2pf	1441	22	for	for	IN
cord-256444-grw5s2pf	1441	23	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1441	24	RNA	RNA	NNP
cord-256444-grw5s2pf	1441	25	to	to	TO
cord-256444-grw5s2pf	1441	26	be	be	VB
cord-256444-grw5s2pf	1441	27	made	make	VBN
cord-256444-grw5s2pf	1441	28	.	.	.
cord-256444-grw5s2pf	1442	1	The	the	DT
cord-256444-grw5s2pf	1442	2	early	early	JJ
cord-256444-grw5s2pf	1442	3	events	event	NNS
cord-256444-grw5s2pf	1442	4	of	of	IN
cord-256444-grw5s2pf	1442	5	viral	viral	JJ
cord-256444-grw5s2pf	1442	6	replication	replication	NN
cord-256444-grw5s2pf	1442	7	have	have	VBP
cord-256444-grw5s2pf	1442	8	so	so	RB
cord-256444-grw5s2pf	1442	9	far	far	RB
cord-256444-grw5s2pf	1442	10	been	be	VBN
cord-256444-grw5s2pf	1442	11	largely	largely	RB
cord-256444-grw5s2pf	1442	12	ignored	ignore	VBN
cord-256444-grw5s2pf	1442	13	.	.	.
cord-256444-grw5s2pf	1443	1	Identification	identification	NN
cord-256444-grw5s2pf	1443	2	of	of	IN
cord-256444-grw5s2pf	1443	3	the	the	DT
cord-256444-grw5s2pf	1443	4	cellular	cellular	JJ
cord-256444-grw5s2pf	1443	5	receptors	receptor	NNS
cord-256444-grw5s2pf	1443	6	for	for	IN
cord-256444-grw5s2pf	1443	7	the	the	DT
cord-256444-grw5s2pf	1443	8	viruses	virus	NNS
cord-256444-grw5s2pf	1443	9	may	may	MD
cord-256444-grw5s2pf	1443	10	finally	finally	RB
cord-256444-grw5s2pf	1443	11	provide	provide	VB
cord-256444-grw5s2pf	1443	12	penetrating	penetrating	JJ
cord-256444-grw5s2pf	1443	13	molecular	molecular	JJ
cord-256444-grw5s2pf	1443	14	tools	tool	NNS
cord-256444-grw5s2pf	1443	15	to	to	TO
cord-256444-grw5s2pf	1443	16	allow	allow	VB
cord-256444-grw5s2pf	1443	17	these	these	DT
cord-256444-grw5s2pf	1443	18	issues	issue	NNS
cord-256444-grw5s2pf	1443	19	to	to	TO
cord-256444-grw5s2pf	1443	20	be	be	VB
cord-256444-grw5s2pf	1443	21	examined	examine	VBN
cord-256444-grw5s2pf	1443	22	.	.	.
cord-256444-grw5s2pf	1444	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1444	2	will	will	MD
cord-256444-grw5s2pf	1444	3	not	not	RB
cord-256444-grw5s2pf	1444	4	be	be	VB
cord-256444-grw5s2pf	1444	5	a	a	DT
cord-256444-grw5s2pf	1444	6	surprise	surprise	NN
cord-256444-grw5s2pf	1444	7	to	to	TO
cord-256444-grw5s2pf	1444	8	discover	discover	VB
cord-256444-grw5s2pf	1444	9	that	that	IN
cord-256444-grw5s2pf	1444	10	virus	virus	NN
cord-256444-grw5s2pf	1444	11	penetration	penetration	NN
cord-256444-grw5s2pf	1444	12	and	and	CC
cord-256444-grw5s2pf	1444	13	uncoating	uncoating	NN
cord-256444-grw5s2pf	1444	14	play	play	NN
cord-256444-grw5s2pf	1444	15	defining	define	VBG
cord-256444-grw5s2pf	1444	16	roles	role	NNS
cord-256444-grw5s2pf	1444	17	in	in	IN
cord-256444-grw5s2pf	1444	18	the	the	DT
cord-256444-grw5s2pf	1444	19	cellular	cellular	JJ
cord-256444-grw5s2pf	1444	20	tropism	tropism	NN
cord-256444-grw5s2pf	1444	21	of	of	IN
cord-256444-grw5s2pf	1444	22	viruses	virus	NNS
cord-256444-grw5s2pf	1444	23	.	.	.
cord-256444-grw5s2pf	1445	1	6	6	LS
cord-256444-grw5s2pf	1445	2	.	.	.
cord-256444-grw5s2pf	1446	1	Are	be	VBP
cord-256444-grw5s2pf	1446	2	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	1446	3	protein	protein	NN
cord-256444-grw5s2pf	1446	4	genes	gene	NNS
cord-256444-grw5s2pf	1446	5	really	really	RB
cord-256444-grw5s2pf	1446	6	unnecessary	unnecessary	JJ
cord-256444-grw5s2pf	1446	7	?	?	.
cord-256444-grw5s2pf	1447	1	Even	even	RB
cord-256444-grw5s2pf	1447	2	if	if	IN
cord-256444-grw5s2pf	1447	3	they	-PRON-	PRP
cord-256444-grw5s2pf	1447	4	are	be	VBP
cord-256444-grw5s2pf	1447	5	auxiliary	auxiliary	JJ
cord-256444-grw5s2pf	1447	6	genes	gene	NNS
cord-256444-grw5s2pf	1447	7	,	,	,
cord-256444-grw5s2pf	1447	8	they	-PRON-	PRP
cord-256444-grw5s2pf	1447	9	may	may	MD
cord-256444-grw5s2pf	1447	10	prove	prove	VB
cord-256444-grw5s2pf	1447	11	to	to	TO
cord-256444-grw5s2pf	1447	12	play	play	VB
cord-256444-grw5s2pf	1447	13	significant	significant	JJ
cord-256444-grw5s2pf	1447	14	roles	role	NNS
cord-256444-grw5s2pf	1447	15	in	in	IN
cord-256444-grw5s2pf	1447	16	the	the	DT
cord-256444-grw5s2pf	1447	17	biology	biology	NN
cord-256444-grw5s2pf	1447	18	of	of	IN
cord-256444-grw5s2pf	1447	19	the	the	DT
cord-256444-grw5s2pf	1447	20	virus	virus	NN
cord-256444-grw5s2pf	1447	21	.	.	.
cord-256444-grw5s2pf	1448	1	7	7	CD
cord-256444-grw5s2pf	1448	2	.	.	.
cord-256444-grw5s2pf	1449	1	Finally	finally	RB
cord-256444-grw5s2pf	1449	2	,	,	,
cord-256444-grw5s2pf	1449	3	what	what	WP
cord-256444-grw5s2pf	1449	4	of	of	IN
cord-256444-grw5s2pf	1449	5	the	the	DT
cord-256444-grw5s2pf	1449	6	potential	potential	JJ
cord-256444-grw5s2pf	1449	7	interaction	interaction	NN
cord-256444-grw5s2pf	1449	8	between	between	IN
cord-256444-grw5s2pf	1449	9	the	the	DT
cord-256444-grw5s2pf	1449	10	virus	virus	NN
cord-256444-grw5s2pf	1449	11	and	and	CC
cord-256444-grw5s2pf	1449	12	host	host	NN
cord-256444-grw5s2pf	1449	13	,	,	,
cord-256444-grw5s2pf	1449	14	which	which	WDT
cord-256444-grw5s2pf	1449	15	has	have	VBZ
cord-256444-grw5s2pf	1449	16	been	be	VBN
cord-256444-grw5s2pf	1449	17	one	one	CD
cord-256444-grw5s2pf	1449	18	of	of	IN
cord-256444-grw5s2pf	1449	19	the	the	DT
cord-256444-grw5s2pf	1449	20	major	major	JJ
cord-256444-grw5s2pf	1449	21	themes	theme	NNS
cord-256444-grw5s2pf	1449	22	of	of	IN
cord-256444-grw5s2pf	1449	23	virology	virology	NN
cord-256444-grw5s2pf	1449	24	in	in	IN
cord-256444-grw5s2pf	1449	25	recent	recent	JJ
cord-256444-grw5s2pf	1449	26	years	year	NNS
cord-256444-grw5s2pf	1449	27	?	?	.
cord-256444-grw5s2pf	1450	1	It	-PRON-	PRP
cord-256444-grw5s2pf	1450	2	may	may	MD
cord-256444-grw5s2pf	1450	3	be	be	VB
cord-256444-grw5s2pf	1450	4	a	a	DT
cord-256444-grw5s2pf	1450	5	little	little	JJ
cord-256444-grw5s2pf	1450	6	premature	premature	JJ
cord-256444-grw5s2pf	1450	7	to	to	TO
cord-256444-grw5s2pf	1450	8	conclude	conclude	VB
cord-256444-grw5s2pf	1450	9	that	that	IN
cord-256444-grw5s2pf	1450	10	cellular	cellular	JJ
cord-256444-grw5s2pf	1450	11	factors	factor	NNS
cord-256444-grw5s2pf	1450	12	play	play	VBP
cord-256444-grw5s2pf	1450	13	major	major	JJ
cord-256444-grw5s2pf	1450	14	roles	role	NNS
cord-256444-grw5s2pf	1450	15	in	in	IN
cord-256444-grw5s2pf	1450	16	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1450	17	replication	replication	NN
cord-256444-grw5s2pf	1450	18	,	,	,
cord-256444-grw5s2pf	1450	19	but	but	CC
cord-256444-grw5s2pf	1450	20	there	there	EX
cord-256444-grw5s2pf	1450	21	is	be	VBZ
cord-256444-grw5s2pf	1450	22	little	little	JJ
cord-256444-grw5s2pf	1450	23	doubt	doubt	NN
cord-256444-grw5s2pf	1450	24	that	that	IN
cord-256444-grw5s2pf	1450	25	cells	cell	NNS
cord-256444-grw5s2pf	1450	26	are	be	VBP
cord-256444-grw5s2pf	1450	27	playing	play	VBG
cord-256444-grw5s2pf	1450	28	more	more	RBR
cord-256444-grw5s2pf	1450	29	active	active	JJ
cord-256444-grw5s2pf	1450	30	roles	role	NNS
cord-256444-grw5s2pf	1450	31	than	than	IN
cord-256444-grw5s2pf	1450	32	was	be	VBD
cord-256444-grw5s2pf	1450	33	previously	previously	RB
cord-256444-grw5s2pf	1450	34	suspected	suspect	VBN
cord-256444-grw5s2pf	1450	35	.	.	.
cord-256444-grw5s2pf	1451	1	Is	be	VBZ
cord-256444-grw5s2pf	1451	2	the	the	DT
cord-256444-grw5s2pf	1451	3	nucleus	nucleus	NN
cord-256444-grw5s2pf	1451	4	contributing	contribute	VBG
cord-256444-grw5s2pf	1451	5	to	to	IN
cord-256444-grw5s2pf	1451	6	the	the	DT
cord-256444-grw5s2pf	1451	7	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1451	8	replication	replication	NN
cord-256444-grw5s2pf	1451	9	?	?	.
cord-256444-grw5s2pf	1452	1	This	this	DT
cord-256444-grw5s2pf	1452	2	may	may	MD
cord-256444-grw5s2pf	1452	3	require	require	VB
cord-256444-grw5s2pf	1452	4	reexamination	reexamination	NN
cord-256444-grw5s2pf	1452	5	.	.	.
cord-256444-grw5s2pf	1453	1	These	these	DT
cord-256444-grw5s2pf	1453	2	are	be	VBP
cord-256444-grw5s2pf	1453	3	but	but	CC
cord-256444-grw5s2pf	1453	4	some	some	DT
cord-256444-grw5s2pf	1453	5	of	of	IN
cord-256444-grw5s2pf	1453	6	the	the	DT
cord-256444-grw5s2pf	1453	7	exciting	exciting	JJ
cord-256444-grw5s2pf	1453	8	challenges	challenge	NNS
cord-256444-grw5s2pf	1453	9	for	for	IN
cord-256444-grw5s2pf	1453	10	the	the	DT
cord-256444-grw5s2pf	1453	11	coronavirologists	coronavirologist	NNS
cord-256444-grw5s2pf	1453	12	to	to	TO
cord-256444-grw5s2pf	1453	13	tackle	tackle	VB
cord-256444-grw5s2pf	1453	14	.	.	.
cord-256444-grw5s2pf	1454	1	The	the	DT
cord-256444-grw5s2pf	1454	2	next	next	JJ
cord-256444-grw5s2pf	1454	3	decade	decade	NN
cord-256444-grw5s2pf	1454	4	should	should	MD
cord-256444-grw5s2pf	1454	5	bring	bring	VB
cord-256444-grw5s2pf	1454	6	us	-PRON-	PRP
cord-256444-grw5s2pf	1454	7	an	an	DT
cord-256444-grw5s2pf	1454	8	even	even	RB
cord-256444-grw5s2pf	1454	9	better	well	JJR
cord-256444-grw5s2pf	1454	10	understanding	understanding	NN
cord-256444-grw5s2pf	1454	11	of	of	IN
cord-256444-grw5s2pf	1454	12	the	the	DT
cord-256444-grw5s2pf	1454	13	various	various	JJ
cord-256444-grw5s2pf	1454	14	aspects	aspect	NNS
cord-256444-grw5s2pf	1454	15	of	of	IN
cord-256444-grw5s2pf	1454	16	the	the	DT
cord-256444-grw5s2pf	1454	17	molecular	molecular	JJ
cord-256444-grw5s2pf	1454	18	biology	biology	NN
cord-256444-grw5s2pf	1454	19	of	of	IN
cord-256444-grw5s2pf	1454	20	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1454	21	.	.	.
cord-256444-grw5s2pf	1455	1	Membrane	membrane	NN
cord-256444-grw5s2pf	1455	2	and	and	CC
cord-256444-grw5s2pf	1455	3	phospholipid	phospholipid	NN
cord-256444-grw5s2pf	1455	4	binding	bind	VBG
cord-256444-grw5s2pf	1455	5	by	by	IN
cord-256444-grw5s2pf	1455	6	murine	murine	NN
cord-256444-grw5s2pf	1455	7	The	the	DT
cord-256444-grw5s2pf	1455	8	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1455	9	sorting	sorting	NN
cord-256444-grw5s2pf	1455	10	domain	domain	NN
cord-256444-grw5s2pf	1455	11	of	of	IN
cord-256444-grw5s2pf	1455	12	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1455	13	E	e	NN
cord-256444-grw5s2pf	1455	14	l	l	NN
cord-256444-grw5s2pf	1455	15	protein	protein	NN
cord-256444-grw5s2pf	1455	16	.	.	.
cord-256444-grw5s2pf	1456	1	coronaviral	coronaviral	NNP
cord-256444-grw5s2pf	1456	2	nucleocapsid	nucleocapsid	NNP
cord-256444-grw5s2pf	1456	3	N	N	NNP
cord-256444-grw5s2pf	1456	4	protein	protein	NN
cord-256444-grw5s2pf	1456	5	Sequence	sequence	NN
cord-256444-grw5s2pf	1456	6	and	and	CC
cord-256444-grw5s2pf	1456	7	topology	topology	NN
cord-256444-grw5s2pf	1456	8	of	of	IN
cord-256444-grw5s2pf	1456	9	a	a	DT
cord-256444-grw5s2pf	1456	10	model	model	NN
cord-256444-grw5s2pf	1456	11	intracellular	intracellular	JJ
cord-256444-grw5s2pf	1456	12	membrane	membrane	NN
cord-256444-grw5s2pf	1456	13	protein	protein	NN
cord-256444-grw5s2pf	1456	14	,	,	,
cord-256444-grw5s2pf	1456	15	E	e	NN
cord-256444-grw5s2pf	1456	16	l	l	NN
cord-256444-grw5s2pf	1456	17	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1456	18	,	,	,
cord-256444-grw5s2pf	1456	19	from	from	IN
cord-256444-grw5s2pf	1456	20	a	a	DT
cord-256444-grw5s2pf	1456	21	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1456	22	Lysosomal	Lysosomal	NNP
cord-256444-grw5s2pf	1456	23	sorting	sort	VBG
cord-256444-grw5s2pf	1456	24	mutants	mutant	NNS
cord-256444-grw5s2pf	1456	25	of	of	IN
cord-256444-grw5s2pf	1456	26	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1456	27	E	e	NN
cord-256444-grw5s2pf	1456	28	l	l	NN
cord-256444-grw5s2pf	1456	29	protein	protein	NN
cord-256444-grw5s2pf	1456	30	,	,	.
cord-256444-grw5s2pf	1457	1	a	a	DT
cord-256444-grw5s2pf	1457	2	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1457	3	membrane	membrane	NN
cord-256444-grw5s2pf	1457	4	protein	protein	NN
cord-256444-grw5s2pf	1457	5	Cell	cell	NN
cord-256444-grw5s2pf	1457	6	fusion	fusion	NN
cord-256444-grw5s2pf	1457	7	studies	study	NNS
cord-256444-grw5s2pf	1457	8	identified	identify	VBD
cord-256444-grw5s2pf	1457	9	multiple	multiple	JJ
cord-256444-grw5s2pf	1457	10	cellular	cellular	JJ
cord-256444-grw5s2pf	1457	11	factors	factor	NNS
cord-256444-grw5s2pf	1457	12	involved	involve	VBN
cord-256444-grw5s2pf	1457	13	in	in	IN
cord-256444-grw5s2pf	1457	14	mouse	mouse	NN
cord-256444-grw5s2pf	1457	15	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1457	16	virus	virus	NN
cord-256444-grw5s2pf	1457	17	entry	entry	NN
cord-256444-grw5s2pf	1457	18	Identification	identification	NN
cord-256444-grw5s2pf	1457	19	of	of	IN
cord-256444-grw5s2pf	1457	20	a	a	DT
cord-256444-grw5s2pf	1457	21	domain	domain	NN
cord-256444-grw5s2pf	1457	22	required	require	VBN
cord-256444-grw5s2pf	1457	23	for	for	IN
cord-256444-grw5s2pf	1457	24	the	the	DT
cord-256444-grw5s2pf	1457	25	autoproteolytic	autoproteolytic	JJ
cord-256444-grw5s2pf	1457	26	cleavage	cleavage	NN
cord-256444-grw5s2pf	1457	27	of	of	IN
cord-256444-grw5s2pf	1457	28	murine	murine	JJ
cord-256444-grw5s2pf	1457	29	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1457	30	gene	gene	NN
cord-256444-grw5s2pf	1457	31	A	A	NNP
cord-256444-grw5s2pf	1457	32	polyprotein	polyprotein	JJ
cord-256444-grw5s2pf	1457	33	Identification	identification	NN
cord-256444-grw5s2pf	1457	34	of	of	IN
cord-256444-grw5s2pf	1457	35	the	the	DT
cord-256444-grw5s2pf	1457	36	catalytic	catalytic	JJ
cord-256444-grw5s2pf	1457	37	sites	site	NNS
cord-256444-grw5s2pf	1457	38	of	of	IN
cord-256444-grw5s2pf	1457	39	a	a	DT
cord-256444-grw5s2pf	1457	40	papain	papain	NN
cord-256444-grw5s2pf	1457	41	-	-	HYPH
cord-256444-grw5s2pf	1457	42	like	like	JJ
cord-256444-grw5s2pf	1457	43	cystein	cystein	NNP
cord-256444-grw5s2pf	1457	44	proteinase	proteinase	NN
cord-256444-grw5s2pf	1457	45	of	of	IN
cord-256444-grw5s2pf	1457	46	murine	murine	JJ
cord-256444-grw5s2pf	1457	47	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1458	1	Two	two	CD
cord-256444-grw5s2pf	1458	2	amino	amino	NN
cord-256444-grw5s2pf	1458	3	acid	acid	NN
cord-256444-grw5s2pf	1458	4	changes	change	NNS
cord-256444-grw5s2pf	1458	5	at	at	IN
cord-256444-grw5s2pf	1458	6	the	the	DT
cord-256444-grw5s2pf	1458	7	N	n	CD
cord-256444-grw5s2pf	1458	8	-	-	HYPH
cord-256444-grw5s2pf	1458	9	terminus	terminus	NN
cord-256444-grw5s2pf	1458	10	of	of	IN
cord-256444-grw5s2pf	1458	11	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1458	12	gastroenteritis	gastroenteritis	JJ
cord-256444-grw5s2pf	1458	13	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1458	14	spike	spike	NN
cord-256444-grw5s2pf	1458	15	protein	protein	NN
cord-256444-grw5s2pf	1458	16	result	result	NN
cord-256444-grw5s2pf	1458	17	in	in	IN
cord-256444-grw5s2pf	1458	18	the	the	DT
cord-256444-grw5s2pf	1458	19	loss	loss	NN
cord-256444-grw5s2pf	1458	20	of	of	IN
cord-256444-grw5s2pf	1458	21	enteric	enteric	JJ
cord-256444-grw5s2pf	1458	22	tropism	tropism	NN
cord-256444-grw5s2pf	1459	1	Random	random	JJ
cord-256444-grw5s2pf	1459	2	nature	nature	NN
cord-256444-grw5s2pf	1459	3	ofcoronavirus	ofcoronavirus	NN
cord-256444-grw5s2pf	1459	4	RNArecombination	rnarecombination	NN
cord-256444-grw5s2pf	1459	5	in	in	IN
cord-256444-grw5s2pf	1459	6	the	the	DT
cord-256444-grw5s2pf	1459	7	absence	absence	NN
cord-256444-grw5s2pf	1459	8	of	of	IN
cord-256444-grw5s2pf	1459	9	selection	selection	NN
cord-256444-grw5s2pf	1459	10	pressure	pressure	NN
cord-256444-grw5s2pf	1459	11	A	a	DT
cord-256444-grw5s2pf	1459	12	clustering	clustering	NN
cord-256444-grw5s2pf	1459	13	of	of	IN
cord-256444-grw5s2pf	1459	14	RNA	RNA	NNP
cord-256444-grw5s2pf	1459	15	recombination	recombination	NN
cord-256444-grw5s2pf	1459	16	sites	site	NNS
cord-256444-grw5s2pf	1459	17	adjacent	adjacent	JJ
cord-256444-grw5s2pf	1459	18	to	to	IN
cord-256444-grw5s2pf	1459	19	a	a	DT
cord-256444-grw5s2pf	1459	20	hypervariable	hypervariable	JJ
cord-256444-grw5s2pf	1459	21	region	region	NN
cord-256444-grw5s2pf	1459	22	of	of	IN
cord-256444-grw5s2pf	1459	23	the	the	DT
cord-256444-grw5s2pf	1459	24	peplomer	peplomer	JJ
cord-256444-grw5s2pf	1459	25	gene	gene	NN
cord-256444-grw5s2pf	1459	26	of	of	IN
cord-256444-grw5s2pf	1459	27	murine	murine	JJ
cord-256444-grw5s2pf	1459	28	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1459	29	Characterization	characterization	NN
cord-256444-grw5s2pf	1459	30	of	of	IN
cord-256444-grw5s2pf	1459	31	leader	leader	NN
cord-256444-grw5s2pf	1459	32	-	-	HYPH
cord-256444-grw5s2pf	1459	33	related	relate	VBN
cord-256444-grw5s2pf	1459	34	small	small	JJ
cord-256444-grw5s2pf	1459	35	RNAs	rna	NNS
cord-256444-grw5s2pf	1459	36	in	in	IN
cord-256444-grw5s2pf	1459	37	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1459	38	-	-	HYPH
cord-256444-grw5s2pf	1459	39	infected	infect	VBN
cord-256444-grw5s2pf	1459	40	cells	cell	NNS
cord-256444-grw5s2pf	1459	41	:	:	:
cord-256444-grw5s2pf	1460	1	Further	further	JJ
cord-256444-grw5s2pf	1460	2	evidence	evidence	NN
cord-256444-grw5s2pf	1460	3	for	for	IN
cord-256444-grw5s2pf	1460	4	leaderprimed	leaderprimed	JJ
cord-256444-grw5s2pf	1460	5	mechanism	mechanism	NN
cord-256444-grw5s2pf	1460	6	of	of	IN
cord-256444-grw5s2pf	1460	7	transcription	transcription	NN
cord-256444-grw5s2pf	1460	8	Analysis	Analysis	NNP
cord-256444-grw5s2pf	1460	9	of	of	IN
cord-256444-grw5s2pf	1460	10	intracellular	intracellular	JJ
cord-256444-grw5s2pf	1460	11	small	small	JJ
cord-256444-grw5s2pf	1460	12	RNAs	rna	NNS
cord-256444-grw5s2pf	1460	13	of	of	IN
cord-256444-grw5s2pf	1460	14	mouse	mouse	NNP
cord-256444-grw5s2pf	1460	15	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1460	16	virus	virus	NN
cord-256444-grw5s2pf	1460	17	:	:	:
cord-256444-grw5s2pf	1460	18	Evidence	evidence	NN
cord-256444-grw5s2pf	1460	19	for	for	IN
cord-256444-grw5s2pf	1460	20	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	1460	21	transcription	transcription	NN
cord-256444-grw5s2pf	1460	22	Interactions	interaction	NNS
cord-256444-grw5s2pf	1460	23	between	between	IN
cord-256444-grw5s2pf	1460	24	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1460	25	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1460	26	protein	protein	NN
cord-256444-grw5s2pf	1460	27	and	and	CC
cord-256444-grw5s2pf	1460	28	viral	viral	JJ
cord-256444-grw5s2pf	1460	29	RNAs	rna	NNS
cord-256444-grw5s2pf	1460	30	:	:	:
cord-256444-grw5s2pf	1460	31	Implications	implication	NNS
cord-256444-grw5s2pf	1460	32	for	for	IN
cord-256444-grw5s2pf	1460	33	viral	viral	JJ
cord-256444-grw5s2pf	1460	34	transcription	transcription	NN
cord-256444-grw5s2pf	1460	35	Establishing	establish	VBG
cord-256444-grw5s2pf	1460	36	a	a	DT
cord-256444-grw5s2pf	1460	37	genetic	genetic	JJ
cord-256444-grw5s2pf	1460	38	recombination	recombination	NN
cord-256444-grw5s2pf	1460	39	map	map	NN
cord-256444-grw5s2pf	1460	40	for	for	IN
cord-256444-grw5s2pf	1460	41	murine	murine	JJ
cord-256444-grw5s2pf	1460	42	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1460	43	strain	strain	NN
cord-256444-grw5s2pf	1460	44	A59	A59	NNP
cord-256444-grw5s2pf	1460	45	complementation	complementation	NN
cord-256444-grw5s2pf	1460	46	groups	group	NNS
cord-256444-grw5s2pf	1461	1	Episodic	episodic	JJ
cord-256444-grw5s2pf	1461	2	evolution	evolution	NN
cord-256444-grw5s2pf	1461	3	mediates	mediate	VBZ
cord-256444-grw5s2pf	1461	4	interspecies	interspecie	NNS
cord-256444-grw5s2pf	1461	5	transfer	transfer	NN
cord-256444-grw5s2pf	1461	6	of	of	IN
cord-256444-grw5s2pf	1461	7	a	a	DT
cord-256444-grw5s2pf	1461	8	murine	murine	JJ
cord-256444-grw5s2pf	1461	9	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1461	10	Interspecies	Interspecies	NNP
cord-256444-grw5s2pf	1461	11	aminopeptidase	aminopeptidase	NN
cord-256444-grw5s2pf	1461	12	-	-	HYPH
cord-256444-grw5s2pf	1461	13	N	n	CD
cord-256444-grw5s2pf	1461	14	chimeras	chimera	NNS
cord-256444-grw5s2pf	1461	15	reveal	reveal	VBP
cord-256444-grw5s2pf	1461	16	species	species	NN
cord-256444-grw5s2pf	1461	17	-	-	HYPH
cord-256444-grw5s2pf	1461	18	specific	specific	JJ
cord-256444-grw5s2pf	1461	19	receptor	receptor	NN
cord-256444-grw5s2pf	1461	20	recognition	recognition	NN
cord-256444-grw5s2pf	1461	21	by	by	IN
cord-256444-grw5s2pf	1461	22	canine	canine	JJ
cord-256444-grw5s2pf	1461	23	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1461	24	,	,	,
cord-256444-grw5s2pf	1461	25	feline	feline	JJ
cord-256444-grw5s2pf	1461	26	infectious	infectious	JJ
cord-256444-grw5s2pf	1461	27	peritonitis	peritonitis	NN
cord-256444-grw5s2pf	1461	28	virus	virus	NN
cord-256444-grw5s2pf	1461	29	In	in	IN
cord-256444-grw5s2pf	1461	30	vivo	vivo	NN
cord-256444-grw5s2pf	1461	31	and	and	CC
cord-256444-grw5s2pf	1461	32	in	in	IN
cord-256444-grw5s2pf	1461	33	vitro	vitro	FW
cord-256444-grw5s2pf	1461	34	models	model	NNS
cord-256444-grw5s2pf	1461	35	of	of	IN
cord-256444-grw5s2pf	1461	36	demyelinating	demyelinate	VBG
cord-256444-grw5s2pf	1461	37	disease	disease	NN
cord-256444-grw5s2pf	1461	38	:	:	:
cord-256444-grw5s2pf	1462	1	Activation	activation	NN
cord-256444-grw5s2pf	1462	2	of	of	IN
cord-256444-grw5s2pf	1462	3	the	the	DT
cord-256444-grw5s2pf	1462	4	adenylate	adenylate	NN
cord-256444-grw5s2pf	1462	5	cyclase	cyclase	NN
cord-256444-grw5s2pf	1462	6	system	system	NN
cord-256444-grw5s2pf	1462	7	influences	influence	VBZ
cord-256444-grw5s2pf	1462	8	JHM	JHM	NNP
cord-256444-grw5s2pf	1462	9	virus	virus	NN
cord-256444-grw5s2pf	1462	10	expression	expression	NN
cord-256444-grw5s2pf	1462	11	in	in	IN
cord-256444-grw5s2pf	1462	12	explanted	explante	VBN
cord-256444-grw5s2pf	1462	13	rat	rat	NN
cord-256444-grw5s2pf	1462	14	oligodendrocytes	oligodendrocyte	NNS
cord-256444-grw5s2pf	1462	15	Mouse	Mouse	NNP
cord-256444-grw5s2pf	1462	16	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1462	17	virus	virus	NN
cord-256444-grw5s2pf	1463	1	strain	strain	VB
cord-256444-grw5s2pf	1463	2	A59	A59	NNP
cord-256444-grw5s2pf	1463	3	RNA	RNA	NNP
cord-256444-grw5s2pf	1463	4	polymerase	polymerase	NN
cord-256444-grw5s2pf	1463	5	gene	gene	NN
cord-256444-grw5s2pf	1463	6	ORF	ORF	NNP
cord-256444-grw5s2pf	1463	7	la	la	NN
cord-256444-grw5s2pf	1463	8	:	:	:
cord-256444-grw5s2pf	1463	9	Heterogeneity	heterogeneity	NN
cord-256444-grw5s2pf	1463	10	among	among	IN
cord-256444-grw5s2pf	1463	11	MHV	MHV	NNP
cord-256444-grw5s2pf	1463	12	strains	strain	VBZ
cord-256444-grw5s2pf	1463	13	Characterization	characterization	NN
cord-256444-grw5s2pf	1463	14	of	of	IN
cord-256444-grw5s2pf	1463	15	the	the	DT
cord-256444-grw5s2pf	1463	16	leader	leader	NN
cord-256444-grw5s2pf	1463	17	papain	papain	NN
cord-256444-grw5s2pf	1463	18	-	-	HYPH
cord-256444-grw5s2pf	1463	19	like	like	JJ
cord-256444-grw5s2pf	1463	20	proteinase	proteinase	NN
cord-256444-grw5s2pf	1463	21	of	of	IN
cord-256444-grw5s2pf	1463	22	MHV	MHV	NNP
cord-256444-grw5s2pf	1463	23	-	-	HYPH
cord-256444-grw5s2pf	1463	24	A59	A59	NNP
cord-256444-grw5s2pf	1463	25	:	:	:
cord-256444-grw5s2pf	1463	26	Identification	identification	NN
cord-256444-grw5s2pf	1463	27	of	of	IN
cord-256444-grw5s2pf	1463	28	a	a	DT
cord-256444-grw5s2pf	1463	29	new	new	JJ
cord-256444-grw5s2pf	1463	30	in	in	FW
cord-256444-grw5s2pf	1463	31	vitro	vitro	FW
cord-256444-grw5s2pf	1463	32	cleavage	cleavage	NN
cord-256444-grw5s2pf	1463	33	site	site	NN
cord-256444-grw5s2pf	1463	34	Characterization	characterization	NN
cord-256444-grw5s2pf	1463	35	of	of	IN
cord-256444-grw5s2pf	1463	36	a	a	DT
cord-256444-grw5s2pf	1463	37	second	second	JJ
cord-256444-grw5s2pf	1463	38	cleavage	cleavage	NN
cord-256444-grw5s2pf	1463	39	site	site	NN
cord-256444-grw5s2pf	1463	40	and	and	CC
cord-256444-grw5s2pf	1463	41	demonstration	demonstration	NN
cord-256444-grw5s2pf	1463	42	of	of	IN
cord-256444-grw5s2pf	1463	43	activity	activity	NN
cord-256444-grw5s2pf	1463	44	in	in	IN
cord-256444-grw5s2pf	1463	45	trans	trans	NNP
cord-256444-grw5s2pf	1463	46	by	by	IN
cord-256444-grw5s2pf	1463	47	the	the	DT
cord-256444-grw5s2pf	1463	48	papain	papain	NN
cord-256444-grw5s2pf	1463	49	-	-	HYPH
cord-256444-grw5s2pf	1463	50	like	like	JJ
cord-256444-grw5s2pf	1463	51	proteinase	proteinase	NN
cord-256444-grw5s2pf	1463	52	of	of	IN
cord-256444-grw5s2pf	1463	53	the	the	DT
cord-256444-grw5s2pf	1463	54	murine	murine	JJ
cord-256444-grw5s2pf	1463	55	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1463	56	mouse	mouse	NN
cord-256444-grw5s2pf	1463	57	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1463	58	virus	virus	NN
cord-256444-grw5s2pf	1464	1	strain	strain	VB
cord-256444-grw5s2pf	1464	2	A59	A59	NNP
cord-256444-grw5s2pf	1464	3	Mutational	Mutational	NNP
cord-256444-grw5s2pf	1464	4	analysis	analysis	NN
cord-256444-grw5s2pf	1464	5	of	of	IN
cord-256444-grw5s2pf	1464	6	the	the	DT
cord-256444-grw5s2pf	1464	7	murine	murine	JJ
cord-256444-grw5s2pf	1464	8	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1464	9	spike	spike	NN
cord-256444-grw5s2pf	1464	10	protein	protein	NN
cord-256444-grw5s2pf	1464	11	:	:	:
cord-256444-grw5s2pf	1465	1	Effect	effect	NN
cord-256444-grw5s2pf	1465	2	on	on	IN
cord-256444-grw5s2pf	1465	3	cell	cell	NN
cord-256444-grw5s2pf	1465	4	-	-	HYPH
cord-256444-grw5s2pf	1465	5	to	to	IN
cord-256444-grw5s2pf	1465	6	-	-	HYPH
cord-256444-grw5s2pf	1465	7	cell	cell	NN
cord-256444-grw5s2pf	1465	8	fusion	fusion	NN
cord-256444-grw5s2pf	1466	1	The	the	DT
cord-256444-grw5s2pf	1466	2	production	production	NN
cord-256444-grw5s2pf	1466	3	of	of	IN
cord-256444-grw5s2pf	1466	4	recombinant	recombinant	JJ
cord-256444-grw5s2pf	1466	5	infectious	infectious	JJ
cord-256444-grw5s2pf	1466	6	DI	di	NN
cord-256444-grw5s2pf	1466	7	-	-	HYPH
cord-256444-grw5s2pf	1466	8	particles	particle	NNS
cord-256444-grw5s2pf	1466	9	of	of	IN
cord-256444-grw5s2pf	1466	10	a	a	DT
cord-256444-grw5s2pf	1466	11	murine	murine	JJ
cord-256444-grw5s2pf	1466	12	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1466	13	in	in	IN
cord-256444-grw5s2pf	1466	14	the	the	DT
cord-256444-grw5s2pf	1466	15	absence	absence	NN
cord-256444-grw5s2pf	1466	16	of	of	IN
cord-256444-grw5s2pf	1466	17	helper	helper	NN
cord-256444-grw5s2pf	1466	18	virus	virus	NN
cord-256444-grw5s2pf	1466	19	Completion	completion	NN
cord-256444-grw5s2pf	1466	20	of	of	IN
cord-256444-grw5s2pf	1466	21	the	the	DT
cord-256444-grw5s2pf	1466	22	sequence	sequence	NN
cord-256444-grw5s2pf	1466	23	of	of	IN
cord-256444-grw5s2pf	1466	24	the	the	DT
cord-256444-grw5s2pf	1466	25	genome	genome	NN
cord-256444-grw5s2pf	1466	26	of	of	IN
cord-256444-grw5s2pf	1466	27	the	the	DT
cord-256444-grw5s2pf	1466	28	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1466	29	avian	avian	JJ
cord-256444-grw5s2pf	1466	30	infectious	infectious	JJ
cord-256444-grw5s2pf	1466	31	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1466	32	virus	virus	NN
cord-256444-grw5s2pf	1466	33	Host	host	NN
cord-256444-grw5s2pf	1466	34	cell	cell	NN
cord-256444-grw5s2pf	1466	35	nuclear	nuclear	JJ
cord-256444-grw5s2pf	1466	36	function	function	NN
cord-256444-grw5s2pf	1466	37	and	and	CC
cord-256444-grw5s2pf	1466	38	murine	murine	JJ
cord-256444-grw5s2pf	1466	39	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1466	40	virus	virus	NN
cord-256444-grw5s2pf	1466	41	replication	replication	NN
cord-256444-grw5s2pf	1466	42	Characterization	characterization	NN
cord-256444-grw5s2pf	1466	43	of	of	IN
cord-256444-grw5s2pf	1466	44	two	two	CD
cord-256444-grw5s2pf	1466	45	RNA	RNA	NNP
cord-256444-grw5s2pf	1466	46	polymerase	polymerase	NN
cord-256444-grw5s2pf	1466	47	activities	activity	NNS
cord-256444-grw5s2pf	1466	48	induced	induce	VBN
cord-256444-grw5s2pf	1466	49	by	by	IN
cord-256444-grw5s2pf	1466	50	mouse	mouse	NNP
cord-256444-grw5s2pf	1466	51	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1466	52	virus	virus	NN
cord-256444-grw5s2pf	1467	1	Further	further	JJ
cord-256444-grw5s2pf	1467	2	characterization	characterization	NN
cord-256444-grw5s2pf	1467	3	of	of	IN
cord-256444-grw5s2pf	1467	4	mouse	mouse	NN
cord-256444-grw5s2pf	1467	5	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1467	6	virus	virus	NN
cord-256444-grw5s2pf	1467	7	RNA	RNA	NNP
cord-256444-grw5s2pf	1467	8	dependent	dependent	JJ
cord-256444-grw5s2pf	1467	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1467	10	polymerases	polymerase	NNS
cord-256444-grw5s2pf	1467	11	The	the	DT
cord-256444-grw5s2pf	1467	12	primary	primary	JJ
cord-256444-grw5s2pf	1467	13	structure	structure	NN
cord-256444-grw5s2pf	1467	14	and	and	CC
cord-256444-grw5s2pf	1467	15	expression	expression	NN
cord-256444-grw5s2pf	1467	16	of	of	IN
cord-256444-grw5s2pf	1467	17	the	the	DT
cord-256444-grw5s2pf	1467	18	second	second	JJ
cord-256444-grw5s2pf	1467	19	open	open	JJ
cord-256444-grw5s2pf	1467	20	reading	reading	NN
cord-256444-grw5s2pf	1467	21	frame	frame	NN
cord-256444-grw5s2pf	1467	22	of	of	IN
cord-256444-grw5s2pf	1467	23	the	the	DT
cord-256444-grw5s2pf	1467	24	polymerase	polymerase	NN
cord-256444-grw5s2pf	1467	25	gene	gene	NN
cord-256444-grw5s2pf	1467	26	of	of	IN
cord-256444-grw5s2pf	1467	27	the	the	DT
cord-256444-grw5s2pf	1467	28	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1467	29	MHV	MHV	NNP
cord-256444-grw5s2pf	1467	30	-	-	HYPH
cord-256444-grw5s2pf	1467	31	A59	A59	NNP
cord-256444-grw5s2pf	1467	32	:	:	:
cord-256444-grw5s2pf	1467	33	A	a	DT
cord-256444-grw5s2pf	1467	34	highly	highly	RB
cord-256444-grw5s2pf	1467	35	conserved	conserved	JJ
cord-256444-grw5s2pf	1467	36	polymerase	polymerase	NN
cord-256444-grw5s2pf	1467	37	is	be	VBZ
cord-256444-grw5s2pf	1467	38	expressed	express	VBN
cord-256444-grw5s2pf	1467	39	by	by	IN
cord-256444-grw5s2pf	1467	40	an	an	DT
cord-256444-grw5s2pf	1467	41	efficient	efficient	JJ
cord-256444-grw5s2pf	1467	42	ribosomal	ribosomal	JJ
cord-256444-grw5s2pf	1467	43	frameshifting	frameshifting	NN
cord-256444-grw5s2pf	1467	44	mechanism	mechanism	NN
cord-256444-grw5s2pf	1468	1	An	an	DT
cord-256444-grw5s2pf	1468	2	efficient	efficient	JJ
cord-256444-grw5s2pf	1468	3	ribosomal	ribosomal	JJ
cord-256444-grw5s2pf	1468	4	frame	frame	NN
cord-256444-grw5s2pf	1468	5	-	-	HYPH
cord-256444-grw5s2pf	1468	6	shifting	shift	VBG
cord-256444-grw5s2pf	1468	7	signal	signal	NN
cord-256444-grw5s2pf	1468	8	in	in	IN
cord-256444-grw5s2pf	1468	9	the	the	DT
cord-256444-grw5s2pf	1468	10	polymeraseencoding	polymeraseencode	VBG
cord-256444-grw5s2pf	1468	11	region	region	NN
cord-256444-grw5s2pf	1468	12	of	of	IN
cord-256444-grw5s2pf	1468	13	the	the	DT
cord-256444-grw5s2pf	1468	14	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1468	15	IBV	IBV	NNP
cord-256444-grw5s2pf	1468	16	Characterization	characterization	NN
cord-256444-grw5s2pf	1468	17	of	of	IN
cord-256444-grw5s2pf	1468	18	an	an	DT
cord-256444-grw5s2pf	1468	19	efficient	efficient	JJ
cord-256444-grw5s2pf	1468	20	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1468	21	ribosomal	ribosomal	JJ
cord-256444-grw5s2pf	1468	22	frame	frame	NN
cord-256444-grw5s2pf	1468	23	-	-	HYPH
cord-256444-grw5s2pf	1468	24	shifting	shift	VBG
cord-256444-grw5s2pf	1468	25	signal	signal	NN
cord-256444-grw5s2pf	1469	1	:	:	:
cord-256444-grw5s2pf	1469	2	Requirement	requirement	NN
cord-256444-grw5s2pf	1469	3	for	for	IN
cord-256444-grw5s2pf	1469	4	an	an	DT
cord-256444-grw5s2pf	1469	5	RNA	RNA	NNP
cord-256444-grw5s2pf	1469	6	pseudoknot	pseudoknot	NN
cord-256444-grw5s2pf	1469	7	.	.	.
cord-256444-grw5s2pf	1470	1	Cell	cell	NN
cord-256444-grw5s2pf	1470	2	(	(	-LRB-
cord-256444-grw5s2pf	1470	3	Cumbridge	Cumbridge	NNP
cord-256444-grw5s2pf	1470	4	Products	Products	NNPS
cord-256444-grw5s2pf	1470	5	of	of	IN
cord-256444-grw5s2pf	1470	6	the	the	DT
cord-256444-grw5s2pf	1470	7	polymerase	polymerase	NN
cord-256444-grw5s2pf	1470	8	-	-	HYPH
cord-256444-grw5s2pf	1470	9	encoding	encode	VBG
cord-256444-grw5s2pf	1470	10	region	region	NN
cord-256444-grw5s2pf	1470	11	of	of	IN
cord-256444-grw5s2pf	1470	12	the	the	DT
cord-256444-grw5s2pf	1470	13	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1470	14	IBV	IBV	NNP
cord-256444-grw5s2pf	1471	1	The	the	DT
cord-256444-grw5s2pf	1471	2	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1471	3	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	1471	4	proteins	protein	NNS
cord-256444-grw5s2pf	1472	1	In	in	IN
cord-256444-grw5s2pf	1472	2	vitro	vitro	FW
cord-256444-grw5s2pf	1472	3	synthesis	synthesis	NN
cord-256444-grw5s2pf	1472	4	of	of	IN
cord-256444-grw5s2pf	1472	5	two	two	CD
cord-256444-grw5s2pf	1472	6	polypeptides	polypeptide	NNS
cord-256444-grw5s2pf	1472	7	from	from	IN
cord-256444-grw5s2pf	1472	8	a	a	DT
cord-256444-grw5s2pf	1472	9	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	1472	10	gene	gene	NN
cord-256444-grw5s2pf	1472	11	of	of	IN
cord-256444-grw5s2pf	1472	12	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1472	13	mouse	mouse	NN
cord-256444-grw5s2pf	1472	14	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1472	15	virus	virus	NN
cord-256444-grw5s2pf	1472	16	strain	strain	NN
cord-256444-grw5s2pf	1473	1	A59	A59	NNP
cord-256444-grw5s2pf	1473	2	Three	three	CD
cord-256444-grw5s2pf	1473	3	intergenic	intergenic	JJ
cord-256444-grw5s2pf	1473	4	regions	region	NNS
cord-256444-grw5s2pf	1473	5	of	of	IN
cord-256444-grw5s2pf	1473	6	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1473	7	mouse	mouse	NN
cord-256444-grw5s2pf	1473	8	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1473	9	virus	virus	NN
cord-256444-grw5s2pf	1473	10	strain	strain	NN
cord-256444-grw5s2pf	1474	1	A59	A59	NNP
cord-256444-grw5s2pf	1474	2	genome	genome	NN
cord-256444-grw5s2pf	1474	3	RNA	RNA	NNP
cord-256444-grw5s2pf	1474	4	contain	contain	VBP
cord-256444-grw5s2pf	1474	5	a	a	DT
cord-256444-grw5s2pf	1474	6	common	common	JJ
cord-256444-grw5s2pf	1474	7	nucleotide	nucleotide	JJ
cord-256444-grw5s2pf	1474	8	sequence	sequence	NN
cord-256444-grw5s2pf	1474	9	that	that	WDT
cord-256444-grw5s2pf	1474	10	is	be	VBZ
cord-256444-grw5s2pf	1474	11	homologous	homologous	JJ
cord-256444-grw5s2pf	1474	12	to	to	IN
cord-256444-grw5s2pf	1474	13	the	the	DT
cord-256444-grw5s2pf	1474	14	3'-end	3'-end	CD
cord-256444-grw5s2pf	1474	15	of	of	IN
cord-256444-grw5s2pf	1474	16	the	the	DT
cord-256444-grw5s2pf	1474	17	viral	viral	JJ
cord-256444-grw5s2pf	1474	18	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1474	19	leader	leader	NN
cord-256444-grw5s2pf	1474	20	sequence	sequence	NN
cord-256444-grw5s2pf	1474	21	Entry	Entry	NNP
cord-256444-grw5s2pf	1474	22	of	of	IN
cord-256444-grw5s2pf	1474	23	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1474	24	into	into	IN
cord-256444-grw5s2pf	1474	25	primate	primate	JJ
cord-256444-grw5s2pf	1474	26	CNS	cns	NN
cord-256444-grw5s2pf	1474	27	following	follow	VBG
cord-256444-grw5s2pf	1474	28	peripheral	peripheral	JJ
cord-256444-grw5s2pf	1474	29	infection	infection	NN
cord-256444-grw5s2pf	1475	1	Further	further	JJ
cord-256444-grw5s2pf	1475	2	studies	study	NNS
cord-256444-grw5s2pf	1475	3	on	on	IN
cord-256444-grw5s2pf	1475	4	human	human	JJ
cord-256444-grw5s2pf	1475	5	enteric	enteric	JJ
cord-256444-grw5s2pf	1475	6	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1475	7	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1475	8	IBV	IBV	NNP
cord-256444-grw5s2pf	1475	9	glycopolypeptides	glycopolypeptide	NNS
cord-256444-grw5s2pf	1475	10	:	:	:
cord-256444-grw5s2pf	1475	11	Size	size	NN
cord-256444-grw5s2pf	1475	12	of	of	IN
cord-256444-grw5s2pf	1475	13	their	-PRON-	PRP$
cord-256444-grw5s2pf	1475	14	polypeptide	polypeptide	NN
cord-256444-grw5s2pf	1475	15	moieties	moiety	NNS
cord-256444-grw5s2pf	1475	16	and	and	CC
cord-256444-grw5s2pf	1475	17	nature	nature	NN
cord-256444-grw5s2pf	1475	18	of	of	IN
cord-256444-grw5s2pf	1475	19	their	-PRON-	PRP$
cord-256444-grw5s2pf	1475	20	oligosaccharides	oligosaccharide	NNS
cord-256444-grw5s2pf	1476	1	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1476	2	IBV	IBV	NNP
cord-256444-grw5s2pf	1476	3	Further	further	JJ
cord-256444-grw5s2pf	1476	4	evidence	evidence	NN
cord-256444-grw5s2pf	1476	5	that	that	IN
cord-256444-grw5s2pf	1476	6	the	the	DT
cord-256444-grw5s2pf	1476	7	surface	surface	NN
cord-256444-grw5s2pf	1476	8	projections	projection	NNS
cord-256444-grw5s2pf	1476	9	are	be	VBP
cord-256444-grw5s2pf	1476	10	associated	associate	VBN
cord-256444-grw5s2pf	1476	11	with	with	IN
cord-256444-grw5s2pf	1476	12	two	two	CD
cord-256444-grw5s2pf	1476	13	glycopolypeptides	glycopolypeptide	NNS
cord-256444-grw5s2pf	1476	14	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1476	15	IBV	IBV	NNP
cord-256444-grw5s2pf	1476	16	:	:	:
cord-256444-grw5s2pf	1477	1	Structural	structural	JJ
cord-256444-grw5s2pf	1477	2	characterization	characterization	NN
cord-256444-grw5s2pf	1477	3	of	of	IN
cord-256444-grw5s2pf	1477	4	the	the	DT
cord-256444-grw5s2pf	1477	5	spike	spike	NN
cord-256444-grw5s2pf	1477	6	protein	protein	NN
cord-256444-grw5s2pf	1478	1	The	the	DT
cord-256444-grw5s2pf	1478	2	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1478	3	surface	surface	NN
cord-256444-grw5s2pf	1478	4	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1478	5	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1478	6	IBV	IBV	NNP
cord-256444-grw5s2pf	1478	7	Removal	Removal	NNP
cord-256444-grw5s2pf	1478	8	of	of	IN
cord-256444-grw5s2pf	1478	9	spike	spike	NN
cord-256444-grw5s2pf	1478	10	glycopolypeptide	glycopolypeptide	NN
cord-256444-grw5s2pf	1478	11	S1	s1	NN
cord-256444-grw5s2pf	1478	12	by	by	IN
cord-256444-grw5s2pf	1478	13	urea	urea	NN
cord-256444-grw5s2pf	1478	14	abolishes	abolish	VBZ
cord-256444-grw5s2pf	1478	15	infectivity	infectivity	NN
cord-256444-grw5s2pf	1478	16	and	and	CC
cord-256444-grw5s2pf	1478	17	haemagglutination	haemagglutination	NN
cord-256444-grw5s2pf	1478	18	but	but	CC
cord-256444-grw5s2pf	1478	19	not	not	RB
cord-256444-grw5s2pf	1478	20	attachment	attachment	NN
cord-256444-grw5s2pf	1478	21	to	to	TO
cord-256444-grw5s2pf	1478	22	cells	cell	NNS
cord-256444-grw5s2pf	1478	23	Sequence	sequence	NN
cord-256444-grw5s2pf	1478	24	analysis	analysis	NN
cord-256444-grw5s2pf	1478	25	of	of	IN
cord-256444-grw5s2pf	1478	26	strains	strain	NNS
cord-256444-grw5s2pf	1478	27	of	of	IN
cord-256444-grw5s2pf	1478	28	avian	avian	JJ
cord-256444-grw5s2pf	1478	29	infectious	infectious	JJ
cord-256444-grw5s2pf	1478	30	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1478	31	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1478	32	isolated	isolate	VBN
cord-256444-grw5s2pf	1478	33	during	during	IN
cord-256444-grw5s2pf	1478	34	the	the	DT
cord-256444-grw5s2pf	1478	35	1960s	1960	NNS
cord-256444-grw5s2pf	1478	36	in	in	IN
cord-256444-grw5s2pf	1478	37	the	the	DT
cord-256444-grw5s2pf	1478	38	UK	UK	NNP
cord-256444-grw5s2pf	1478	39	Coronaviruses	Coronaviruses	NNP
cord-256444-grw5s2pf	1478	40	.	.	.
cord-256444-grw5s2pf	1479	1	In	in	IN
cord-256444-grw5s2pf	1479	2	"	"	``
cord-256444-grw5s2pf	1479	3	Principles	Principles	NNPS
cord-256444-grw5s2pf	1479	4	and	and	CC
cord-256444-grw5s2pf	1479	5	Practice	practice	NN
cord-256444-grw5s2pf	1479	6	of	of	IN
cord-256444-grw5s2pf	1479	7	Clinical	Clinical	NNP
cord-256444-grw5s2pf	1479	8	Virology	Virology	NNP
cord-256444-grw5s2pf	1479	9	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1479	10	IBV	IBV	NNP
cord-256444-grw5s2pf	1479	11	Partial	partial	JJ
cord-256444-grw5s2pf	1479	12	amino	amino	NN
cord-256444-grw5s2pf	1479	13	terminal	terminal	NN
cord-256444-grw5s2pf	1479	14	sequencing	sequencing	NN
cord-256444-grw5s2pf	1479	15	of	of	IN
cord-256444-grw5s2pf	1479	16	the	the	DT
cord-256444-grw5s2pf	1479	17	spike	spike	NN
cord-256444-grw5s2pf	1479	18	polypeptide	polypeptide	NN
cord-256444-grw5s2pf	1479	19	S2	S2	NNP
cord-256444-grw5s2pf	1479	20	identifies	identify	VBZ
cord-256444-grw5s2pf	1479	21	the	the	DT
cord-256444-grw5s2pf	1479	22	sequence	sequence	NN
cord-256444-grw5s2pf	1479	23	ArgArg	argarg	NN
cord-256444-grw5s2pf	1479	24	-	-	HYPH
cord-256444-grw5s2pf	1479	25	Phe	phe	NN
cord-256444-grw5s2pf	1479	26	-	-	HYPH
cord-256444-grw5s2pf	1479	27	Arg	arg	NN
cord-256444-grw5s2pf	1479	28	-	-	HYPH
cord-256444-grw5s2pf	1479	29	Arg	arg	NN
cord-256444-grw5s2pf	1479	30	at	at	IN
cord-256444-grw5s2pf	1479	31	the	the	DT
cord-256444-grw5s2pf	1479	32	cleavage	cleavage	NN
cord-256444-grw5s2pf	1479	33	site	site	NN
cord-256444-grw5s2pf	1479	34	of	of	IN
cord-256444-grw5s2pf	1479	35	the	the	DT
cord-256444-grw5s2pf	1479	36	spike	spike	NN
cord-256444-grw5s2pf	1479	37	precursor	precursor	NN
cord-256444-grw5s2pf	1479	38	propolypeptide	propolypeptide	NN
cord-256444-grw5s2pf	1479	39	of	of	IN
cord-256444-grw5s2pf	1479	40	IBV	IBV	NNP
cord-256444-grw5s2pf	1479	41	strains	strain	NNS
cord-256444-grw5s2pf	1480	1	Beaudette	Beaudette	NNP
cord-256444-grw5s2pf	1480	2	and	and	CC
cord-256444-grw5s2pf	1480	3	M41	M41	NNP
cord-256444-grw5s2pf	1480	4	Amino	Amino	NNP
cord-256444-grw5s2pf	1480	5	acids	acid	NNS
cord-256444-grw5s2pf	1480	6	within	within	IN
cord-256444-grw5s2pf	1480	7	hypervariable	hypervariable	JJ
cord-256444-grw5s2pf	1480	8	region	region	NN
cord-256444-grw5s2pf	1480	9	1	1	CD
cord-256444-grw5s2pf	1480	10	of	of	IN
cord-256444-grw5s2pf	1480	11	avian	avian	JJ
cord-256444-grw5s2pf	1480	12	coronarvirus	coronarvirus	JJ
cord-256444-grw5s2pf	1480	13	IBV	IBV	NNP
cord-256444-grw5s2pf	1480	14	(	(	-LRB-
cord-256444-grw5s2pf	1480	15	Massachusetts	Massachusetts	NNP
cord-256444-grw5s2pf	1480	16	serotype	serotype	NN
cord-256444-grw5s2pf	1480	17	)	)	-RRB-
cord-256444-grw5s2pf	1480	18	spike	spike	NN
cord-256444-grw5s2pf	1480	19	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1480	20	are	be	VBP
cord-256444-grw5s2pf	1480	21	associated	associate	VBN
cord-256444-grw5s2pf	1480	22	with	with	IN
cord-256444-grw5s2pf	1480	23	neutralization	neutralization	NN
cord-256444-grw5s2pf	1480	24	epitopes	epitope	NNS
cord-256444-grw5s2pf	1480	25	Recommendations	Recommendations	NNPS
cord-256444-grw5s2pf	1480	26	of	of	IN
cord-256444-grw5s2pf	1480	27	the	the	DT
cord-256444-grw5s2pf	1480	28	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1480	29	Study	Study	NNP
cord-256444-grw5s2pf	1480	30	Group	Group	NNP
cord-256444-grw5s2pf	1480	31	for	for	IN
cord-256444-grw5s2pf	1480	32	the	the	DT
cord-256444-grw5s2pf	1480	33	nomenclature	nomenclature	NN
cord-256444-grw5s2pf	1480	34	of	of	IN
cord-256444-grw5s2pf	1480	35	the	the	DT
cord-256444-grw5s2pf	1480	36	structural	structural	JJ
cord-256444-grw5s2pf	1480	37	proteins	protein	NNS
cord-256444-grw5s2pf	1480	38	,	,	,
cord-256444-grw5s2pf	1480	39	mRNAs	mrnas	CD
cord-256444-grw5s2pf	1480	40	and	and	CC
cord-256444-grw5s2pf	1480	41	genes	gene	NNS
cord-256444-grw5s2pf	1480	42	of	of	IN
cord-256444-grw5s2pf	1480	43	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1480	44	Revision	Revision	NNP
cord-256444-grw5s2pf	1480	45	of	of	IN
cord-256444-grw5s2pf	1480	46	the	the	DT
cord-256444-grw5s2pf	1480	47	taxonomy	taxonomy	NN
cord-256444-grw5s2pf	1480	48	of	of	IN
cord-256444-grw5s2pf	1480	49	the	the	DT
cord-256444-grw5s2pf	1480	50	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1480	51	,	,	,
cord-256444-grw5s2pf	1480	52	Torovirus	Torovirus	NNP
cord-256444-grw5s2pf	1480	53	and	and	CC
cord-256444-grw5s2pf	1480	54	Arterivirus	Arterivirus	NNP
cord-256444-grw5s2pf	1480	55	genera	genera	VBP
cord-256444-grw5s2pf	1480	56	Coronaviridae	Coronaviridae	NNP
cord-256444-grw5s2pf	1480	57	.	.	.
cord-256444-grw5s2pf	1481	1	In	in	IN
cord-256444-grw5s2pf	1481	2	"	"	``
cord-256444-grw5s2pf	1481	3	Virus	Virus	NNP
cord-256444-grw5s2pf	1481	4	Taxonomy	Taxonomy	NNP
cord-256444-grw5s2pf	1481	5	.	.	.
cord-256444-grw5s2pf	1482	1	Sixth	Sixth	NNP
cord-256444-grw5s2pf	1482	2	Report	Report	NNP
cord-256444-grw5s2pf	1482	3	ofthe	ofthe	DT
cord-256444-grw5s2pf	1482	4	International	International	NNP
cord-256444-grw5s2pf	1482	5	Committee	Committee	NNP
cord-256444-grw5s2pf	1482	6	on	on	IN
cord-256444-grw5s2pf	1482	7	Taxonomy	Taxonomy	NNP
cord-256444-grw5s2pf	1482	8	ofviruses	ofviruse	NNS
cord-256444-grw5s2pf	1483	1	Cis	Cis	NNP
cord-256444-grw5s2pf	1483	2	requirement	requirement	NN
cord-256444-grw5s2pf	1483	3	for	for	IN
cord-256444-grw5s2pf	1483	4	N	n	CD
cord-256444-grw5s2pf	1483	5	-	-	HYPH
cord-256444-grw5s2pf	1483	6	specific	specific	JJ
cord-256444-grw5s2pf	1483	7	protein	protein	NN
cord-256444-grw5s2pf	1483	8	sequence	sequence	NN
cord-256444-grw5s2pf	1483	9	in	in	IN
cord-256444-grw5s2pf	1483	10	bovine	bovine	JJ
cord-256444-grw5s2pf	1483	11	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1483	12	defective	defective	JJ
cord-256444-grw5s2pf	1483	13	interfering	interfere	VBG
cord-256444-grw5s2pf	1483	14	RNA	RNA	NNP
cord-256444-grw5s2pf	1483	15	replication	replication	NN
cord-256444-grw5s2pf	1483	16	A	a	DT
cord-256444-grw5s2pf	1483	17	cis	cis	NN
cord-256444-grw5s2pf	1483	18	-	-	HYPH
cord-256444-grw5s2pf	1483	19	acting	act	VBG
cord-256444-grw5s2pf	1483	20	function	function	NN
cord-256444-grw5s2pf	1483	21	for	for	IN
cord-256444-grw5s2pf	1483	22	the	the	DT
cord-256444-grw5s2pf	1483	23	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1483	24	leader	leader	NN
cord-256444-grw5s2pf	1483	25	in	in	IN
cord-256444-grw5s2pf	1483	26	defective	defective	JJ
cord-256444-grw5s2pf	1483	27	-	-	HYPH
cord-256444-grw5s2pf	1483	28	interfering	interfere	VBG
cord-256444-grw5s2pf	1483	29	RNA	RNA	NNP
cord-256444-grw5s2pf	1483	30	replication	replication	NN
cord-256444-grw5s2pf	1484	1	The	the	DT
cord-256444-grw5s2pf	1484	2	UCUAAAC	UCUAAAC	NNP
cord-256444-grw5s2pf	1484	3	promoter	promoter	NN
cord-256444-grw5s2pf	1484	4	motif	motif	NN
cord-256444-grw5s2pf	1484	5	is	be	VBZ
cord-256444-grw5s2pf	1484	6	not	not	RB
cord-256444-grw5s2pf	1484	7	required	require	VBN
cord-256444-grw5s2pf	1484	8	for	for	IN
cord-256444-grw5s2pf	1484	9	high	high	JJ
cord-256444-grw5s2pf	1484	10	-	-	HYPH
cord-256444-grw5s2pf	1484	11	frequency	frequency	NN
cord-256444-grw5s2pf	1484	12	leader	leader	NN
cord-256444-grw5s2pf	1484	13	recombination	recombination	NN
cord-256444-grw5s2pf	1484	14	in	in	IN
cord-256444-grw5s2pf	1484	15	bovine	bovine	JJ
cord-256444-grw5s2pf	1484	16	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1484	17	defective	defective	JJ
cord-256444-grw5s2pf	1484	18	interfering	interfere	VBG
cord-256444-grw5s2pf	1484	19	RNA	RNA	NNP
cord-256444-grw5s2pf	1484	20	Induction	Induction	NNP
cord-256444-grw5s2pf	1484	21	of	of	IN
cord-256444-grw5s2pf	1484	22	alpha	alpha	NN
cord-256444-grw5s2pf	1484	23	interferon	interferon	NN
cord-256444-grw5s2pf	1484	24	by	by	IN
cord-256444-grw5s2pf	1484	25	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1484	26	gastroenteritis	gastroenteritis	JJ
cord-256444-grw5s2pf	1484	27	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1484	28	:	:	:
cord-256444-grw5s2pf	1484	29	Role	role	NN
cord-256444-grw5s2pf	1484	30	of	of	IN
cord-256444-grw5s2pf	1484	31	transmembrane	transmembrane	NN
cord-256444-grw5s2pf	1484	32	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1484	33	El	El	NNP
cord-256444-grw5s2pf	1484	34	Cytopathology	Cytopathology	NNP
cord-256444-grw5s2pf	1484	35	of	of	IN
cord-256444-grw5s2pf	1484	36	chick	chick	NN
cord-256444-grw5s2pf	1484	37	renal	renal	JJ
cord-256444-grw5s2pf	1484	38	epithelial	epithelial	JJ
cord-256444-grw5s2pf	1484	39	cells	cell	NNS
cord-256444-grw5s2pf	1484	40	experimentally	experimentally	RB
cord-256444-grw5s2pf	1484	41	infected	infect	VBN
cord-256444-grw5s2pf	1484	42	with	with	IN
cord-256444-grw5s2pf	1484	43	avian	avian	JJ
cord-256444-grw5s2pf	1484	44	infectious	infectious	JJ
cord-256444-grw5s2pf	1484	45	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1484	46	virus	virus	NN
cord-256444-grw5s2pf	1485	1	A	a	DT
cord-256444-grw5s2pf	1485	2	pregnancy	pregnancy	NN
cord-256444-grw5s2pf	1485	3	-	-	HYPH
cord-256444-grw5s2pf	1485	4	specific	specific	JJ
cord-256444-grw5s2pf	1485	5	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1485	6	is	be	VBZ
cord-256444-grw5s2pf	1485	7	expressed	express	VBN
cord-256444-grw5s2pf	1485	8	in	in	IN
cord-256444-grw5s2pf	1485	9	the	the	DT
cord-256444-grw5s2pf	1485	10	brain	brain	NN
cord-256444-grw5s2pf	1485	11	and	and	CC
cord-256444-grw5s2pf	1485	12	serves	serve	VBZ
cord-256444-grw5s2pf	1485	13	as	as	IN
cord-256444-grw5s2pf	1485	14	a	a	DT
cord-256444-grw5s2pf	1485	15	receptor	receptor	NN
cord-256444-grw5s2pf	1485	16	for	for	IN
cord-256444-grw5s2pf	1485	17	mouse	mouse	NN
cord-256444-grw5s2pf	1485	18	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1485	19	virus	virus	NN
cord-256444-grw5s2pf	1485	20	Human	Human	NNP
cord-256444-grw5s2pf	1485	21	carcinoembryonic	carcinoembryonic	NNP
cord-256444-grw5s2pf	1485	22	antigen	antigen	NN
cord-256444-grw5s2pf	1485	23	and	and	CC
cord-256444-grw5s2pf	1485	24	biliary	biliary	JJ
cord-256444-grw5s2pf	1485	25	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1485	26	can	can	MD
cord-256444-grw5s2pf	1485	27	serve	serve	VB
cord-256444-grw5s2pf	1485	28	as	as	IN
cord-256444-grw5s2pf	1485	29	mouse	mouse	NN
cord-256444-grw5s2pf	1485	30	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1485	31	virus	virus	NN
cord-256444-grw5s2pf	1485	32	receptors	receptor	NNS
cord-256444-grw5s2pf	1485	33	Function	function	VB
cord-256444-grw5s2pf	1485	34	ofa	ofa	NN
cord-256444-grw5s2pf	1485	35	5'-end	5'-end	CD
cord-256444-grw5s2pf	1485	36	genomic	genomic	JJ
cord-256444-grw5s2pf	1485	37	RNAmutation	rnamutation	NN
cord-256444-grw5s2pf	1485	38	that	that	WDT
cord-256444-grw5s2pf	1485	39	evolves	evolve	VBZ
cord-256444-grw5s2pf	1485	40	during	during	IN
cord-256444-grw5s2pf	1485	41	persistent	persistent	JJ
cord-256444-grw5s2pf	1485	42	mouse	mouse	NN
cord-256444-grw5s2pf	1485	43	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1485	44	virus	virus	NN
cord-256444-grw5s2pf	1485	45	infection	infection	NN
cord-256444-grw5s2pf	1485	46	in	in	IN
cord-256444-grw5s2pf	1485	47	vitro	vitro	FW
cord-256444-grw5s2pf	1485	48	Molecular	molecular	JJ
cord-256444-grw5s2pf	1485	49	anatomy	anatomy	NN
cord-256444-grw5s2pf	1485	50	of	of	IN
cord-256444-grw5s2pf	1485	51	mouse	mouse	NN
cord-256444-grw5s2pf	1485	52	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1485	53	virus	virus	NN
cord-256444-grw5s2pf	1485	54	persistence	persistence	NN
cord-256444-grw5s2pf	1485	55	:	:	:
cord-256444-grw5s2pf	1485	56	Coevolution	coevolution	NN
cord-256444-grw5s2pf	1485	57	of	of	IN
cord-256444-grw5s2pf	1485	58	increased	increase	VBN
cord-256444-grw5s2pf	1485	59	host	host	NN
cord-256444-grw5s2pf	1485	60	cell	cell	NN
cord-256444-grw5s2pf	1485	61	resistance	resistance	NN
cord-256444-grw5s2pf	1485	62	and	and	CC
cord-256444-grw5s2pf	1485	63	virus	virus	NN
cord-256444-grw5s2pf	1485	64	virulence	virulence	NN
cord-256444-grw5s2pf	1485	65	Human	human	JJ
cord-256444-grw5s2pf	1485	66	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1485	67	OC43	OC43	NNP
cord-256444-grw5s2pf	1485	68	interacts	interact	VBZ
cord-256444-grw5s2pf	1485	69	with	with	IN
cord-256444-grw5s2pf	1485	70	major	major	JJ
cord-256444-grw5s2pf	1485	71	histocompatibility	histocompatibility	NN
cord-256444-grw5s2pf	1485	72	complex	complex	JJ
cord-256444-grw5s2pf	1485	73	class	class	NN
cord-256444-grw5s2pf	1485	74	I	-PRON-	PRP
cord-256444-grw5s2pf	1485	75	molecules	molecule	NNS
cord-256444-grw5s2pf	1485	76	at	at	IN
cord-256444-grw5s2pf	1485	77	the	the	DT
cord-256444-grw5s2pf	1485	78	cell	cell	NN
cord-256444-grw5s2pf	1485	79	surface	surface	NN
cord-256444-grw5s2pf	1485	80	to	to	TO
cord-256444-grw5s2pf	1485	81	establish	establish	VB
cord-256444-grw5s2pf	1485	82	infection	infection	NN
cord-256444-grw5s2pf	1485	83	Monoclonal	monoclonal	JJ
cord-256444-grw5s2pf	1485	84	antibodies	antibody	NNS
cord-256444-grw5s2pf	1485	85	to	to	IN
cord-256444-grw5s2pf	1485	86	murine	murine	JJ
cord-256444-grw5s2pf	1485	87	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1485	88	virus-4	virus-4	NNP
cord-256444-grw5s2pf	1486	1	(	(	-LRB-
cord-256444-grw5s2pf	1486	2	strain	strain	NN
cord-256444-grw5s2pf	1486	3	JHM	JHM	NNP
cord-256444-grw5s2pf	1486	4	)	)	-RRB-
cord-256444-grw5s2pf	1486	5	define	define	VB
cord-256444-grw5s2pf	1486	6	the	the	DT
cord-256444-grw5s2pf	1486	7	viral	viral	JJ
cord-256444-grw5s2pf	1486	8	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1486	9	responsible	responsible	JJ
cord-256444-grw5s2pf	1486	10	for	for	IN
cord-256444-grw5s2pf	1486	11	attachment	attachment	NN
cord-256444-grw5s2pf	1486	12	and	and	CC
cord-256444-grw5s2pf	1486	13	cell	cell	NN
cord-256444-grw5s2pf	1486	14	-	-	HYPH
cord-256444-grw5s2pf	1486	15	cell	cell	NN
cord-256444-grw5s2pf	1486	16	fusion	fusion	NN
cord-256444-grw5s2pf	1486	17	Enterotropic	Enterotropic	NNP
cord-256444-grw5s2pf	1486	18	strains	strain	NNS
cord-256444-grw5s2pf	1486	19	of	of	IN
cord-256444-grw5s2pf	1486	20	mouse	mouse	NN
cord-256444-grw5s2pf	1486	21	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1486	22	differ	differ	VBP
cord-256444-grw5s2pf	1486	23	in	in	IN
cord-256444-grw5s2pf	1486	24	their	-PRON-	PRP$
cord-256444-grw5s2pf	1486	25	use	use	NN
cord-256444-grw5s2pf	1486	26	of	of	IN
cord-256444-grw5s2pf	1486	27	murine	murine	JJ
cord-256444-grw5s2pf	1486	28	carcinoembryonic	carcinoembryonic	NNP
cord-256444-grw5s2pf	1486	29	antigen	antigen	NN
cord-256444-grw5s2pf	1486	30	-	-	HYPH
cord-256444-grw5s2pf	1486	31	related	relate	VBN
cord-256444-grw5s2pf	1486	32	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1486	33	receptors	receptor	NNS
cord-256444-grw5s2pf	1487	1	In	in	IN
cord-256444-grw5s2pf	1487	2	vitro	vitro	FW
cord-256444-grw5s2pf	1487	3	replication	replication	NN
cord-256444-grw5s2pf	1487	4	of	of	IN
cord-256444-grw5s2pf	1487	5	mouse	mouse	NN
cord-256444-grw5s2pf	1487	6	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1487	7	virus	virus	NN
cord-256444-grw5s2pf	1487	8	strain	strain	VBP
cord-256444-grw5s2pf	1487	9	A59	A59	NNP
cord-256444-grw5s2pf	1487	10	Epidemiology	Epidemiology	NNP
cord-256444-grw5s2pf	1487	11	of	of	IN
cord-256444-grw5s2pf	1487	12	infectious	infectious	JJ
cord-256444-grw5s2pf	1487	13	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1487	14	virus	virus	NN
cord-256444-grw5s2pf	1487	15	Monoclonal	Monoclonal	NNP
cord-256444-grw5s2pf	1487	16	antibody	antibody	NN
cord-256444-grw5s2pf	1487	17	analysis	analysis	NN
cord-256444-grw5s2pf	1487	18	of	of	IN
cord-256444-grw5s2pf	1487	19	neutralization	neutralization	NN
cord-256444-grw5s2pf	1487	20	and	and	CC
cord-256444-grw5s2pf	1487	21	antibody	antibody	NN
cord-256444-grw5s2pf	1487	22	-	-	HYPH
cord-256444-grw5s2pf	1487	23	dependent	dependent	JJ
cord-256444-grw5s2pf	1487	24	enhancement	enhancement	NN
cord-256444-grw5s2pf	1487	25	of	of	IN
cord-256444-grw5s2pf	1487	26	feline	feline	JJ
cord-256444-grw5s2pf	1487	27	infectious	infectious	JJ
cord-256444-grw5s2pf	1487	28	peritonitis	peritonitis	NN
cord-256444-grw5s2pf	1487	29	virus	virus	NN
cord-256444-grw5s2pf	1487	30	B	b	NN
cord-256444-grw5s2pf	1487	31	lymphocyte	lymphocyte	NN
cord-256444-grw5s2pf	1487	32	and	and	CC
cord-256444-grw5s2pf	1487	33	macrophage	macrophage	NN
cord-256444-grw5s2pf	1487	34	expression	expression	NN
cord-256444-grw5s2pf	1487	35	of	of	IN
cord-256444-grw5s2pf	1487	36	carcinoembryonic	carcinoembryonic	NNP
cord-256444-grw5s2pf	1487	37	antigen	antigen	NN
cord-256444-grw5s2pf	1487	38	-	-	HYPH
cord-256444-grw5s2pf	1487	39	related	relate	VBN
cord-256444-grw5s2pf	1487	40	adhesion	adhesion	NN
cord-256444-grw5s2pf	1487	41	molecules	molecule	NNS
cord-256444-grw5s2pf	1487	42	that	that	WDT
cord-256444-grw5s2pf	1487	43	serve	serve	VBP
cord-256444-grw5s2pf	1487	44	as	as	IN
cord-256444-grw5s2pf	1487	45	receptors	receptor	NNS
cord-256444-grw5s2pf	1487	46	for	for	IN
cord-256444-grw5s2pf	1487	47	murine	murine	JJ
cord-256444-grw5s2pf	1487	48	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1487	49	Intestinal	intestinal	JJ
cord-256444-grw5s2pf	1487	50	replication	replication	NN
cord-256444-grw5s2pf	1487	51	of	of	IN
cord-256444-grw5s2pf	1487	52	a	a	DT
cord-256444-grw5s2pf	1487	53	respiratory	respiratory	JJ
cord-256444-grw5s2pf	1487	54	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1487	55	closely	closely	RB
cord-256444-grw5s2pf	1487	56	related	relate	VBN
cord-256444-grw5s2pf	1487	57	antigenically	antigenically	RB
cord-256444-grw5s2pf	1487	58	to	to	IN
cord-256444-grw5s2pf	1487	59	the	the	DT
cord-256444-grw5s2pf	1487	60	enteric	enteric	JJ
cord-256444-grw5s2pf	1487	61	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1487	62	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1487	63	virus	virus	NN
cord-256444-grw5s2pf	1487	64	Bovine	bovine	JJ
cord-256444-grw5s2pf	1487	65	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1487	66	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	1487	67	protein	protein	NN
cord-256444-grw5s2pf	1487	68	ns2	ns2	NNP
cord-256444-grw5s2pf	1487	69	is	be	VBZ
cord-256444-grw5s2pf	1487	70	a	a	DT
cord-256444-grw5s2pf	1487	71	phosphoprotein	phosphoprotein	JJ
cord-256444-grw5s2pf	1487	72	Induction	Induction	NNP
cord-256444-grw5s2pf	1487	73	of	of	IN
cord-256444-grw5s2pf	1487	74	macrophage	macrophage	NN
cord-256444-grw5s2pf	1487	75	procoagulant	procoagulant	NN
cord-256444-grw5s2pf	1487	76	activity	activity	NN
cord-256444-grw5s2pf	1487	77	by	by	IN
cord-256444-grw5s2pf	1487	78	murine	murine	JJ
cord-256444-grw5s2pf	1487	79	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1487	80	virus	virus	NN
cord-256444-grw5s2pf	1487	81	strain	strain	NN
cord-256444-grw5s2pf	1487	82	3	3	CD
cord-256444-grw5s2pf	1487	83	:	:	:
cord-256444-grw5s2pf	1487	84	Role	role	NN
cord-256444-grw5s2pf	1487	85	of	of	IN
cord-256444-grw5s2pf	1487	86	tyrosine	tyrosine	NN
cord-256444-grw5s2pf	1487	87	phosphorylation	phosphorylation	NN
cord-256444-grw5s2pf	1487	88	Pathogenesis	Pathogenesis	NNP
cord-256444-grw5s2pf	1487	89	and	and	CC
cord-256444-grw5s2pf	1487	90	diseases	disease	NNS
cord-256444-grw5s2pf	1487	91	of	of	IN
cord-256444-grw5s2pf	1487	92	the	the	DT
cord-256444-grw5s2pf	1487	93	central	central	JJ
cord-256444-grw5s2pf	1487	94	nervous	nervous	JJ
cord-256444-grw5s2pf	1487	95	system	system	NN
cord-256444-grw5s2pf	1487	96	caused	cause	VBN
cord-256444-grw5s2pf	1487	97	by	by	IN
cord-256444-grw5s2pf	1487	98	murine	murine	JJ
cord-256444-grw5s2pf	1487	99	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1487	100	Site	site	NN
cord-256444-grw5s2pf	1487	101	-	-	HYPH
cord-256444-grw5s2pf	1487	102	specific	specific	JJ
cord-256444-grw5s2pf	1487	103	alteration	alteration	NN
cord-256444-grw5s2pf	1487	104	of	of	IN
cord-256444-grw5s2pf	1487	105	murine	murine	JJ
cord-256444-grw5s2pf	1487	106	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1487	107	virus	virus	NN
cord-256444-grw5s2pf	1488	1	type-4	type-4	NNP
cord-256444-grw5s2pf	1489	1	(	(	-LRB-
cord-256444-grw5s2pf	1489	2	MHV-4	MHV-4	NNP
cord-256444-grw5s2pf	1489	3	)	)	-RRB-
cord-256444-grw5s2pf	1490	1	peplomer	peplomer	NNP
cord-256444-grw5s2pf	1490	2	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1490	3	E2	E2	NNP
cord-256444-grw5s2pf	1490	4	results	result	NNS
cord-256444-grw5s2pf	1490	5	in	in	IN
cord-256444-grw5s2pf	1490	6	reduced	reduce	VBN
cord-256444-grw5s2pf	1490	7	neurovirulence	neurovirulence	NN
cord-256444-grw5s2pf	1491	1	An	an	DT
cord-256444-grw5s2pf	1491	2	electron	electron	NN
cord-256444-grw5s2pf	1491	3	microscope	microscope	NN
cord-256444-grw5s2pf	1491	4	study	study	NN
cord-256444-grw5s2pf	1491	5	of	of	IN
cord-256444-grw5s2pf	1491	6	the	the	DT
cord-256444-grw5s2pf	1491	7	development	development	NN
cord-256444-grw5s2pf	1491	8	of	of	IN
cord-256444-grw5s2pf	1491	9	a	a	DT
cord-256444-grw5s2pf	1491	10	mouse	mouse	NN
cord-256444-grw5s2pf	1491	11	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1491	12	virus	virus	NN
cord-256444-grw5s2pf	1491	13	in	in	IN
cord-256444-grw5s2pf	1491	14	tissue	tissue	NN
cord-256444-grw5s2pf	1491	15	culture	culture	NN
cord-256444-grw5s2pf	1491	16	cells	cell	NNS
cord-256444-grw5s2pf	1491	17	Identification	identification	NN
cord-256444-grw5s2pf	1491	18	of	of	IN
cord-256444-grw5s2pf	1491	19	the	the	DT
cord-256444-grw5s2pf	1491	20	structural	structural	JJ
cord-256444-grw5s2pf	1491	21	proteins	protein	NNS
cord-256444-grw5s2pf	1491	22	of	of	IN
cord-256444-grw5s2pf	1491	23	turkey	turkey	NN
cord-256444-grw5s2pf	1491	24	enteric	enteric	JJ
cord-256444-grw5s2pf	1491	25	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1491	26	Evidence	evidence	NN
cord-256444-grw5s2pf	1491	27	for	for	IN
cord-256444-grw5s2pf	1491	28	a	a	DT
cord-256444-grw5s2pf	1491	29	coiled	coil	VBN
cord-256444-grw5s2pf	1491	30	-	-	HYPH
cord-256444-grw5s2pf	1491	31	coil	coil	NN
cord-256444-grw5s2pf	1491	32	structure	structure	NN
cord-256444-grw5s2pf	1491	33	in	in	IN
cord-256444-grw5s2pf	1491	34	the	the	DT
cord-256444-grw5s2pf	1491	35	spike	spike	NN
cord-256444-grw5s2pf	1491	36	proteins	protein	NNS
cord-256444-grw5s2pf	1491	37	of	of	IN
cord-256444-grw5s2pf	1491	38	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1491	39	Stably	stably	RB
cord-256444-grw5s2pf	1491	40	expressed	express	VBD
cord-256444-grw5s2pf	1491	41	FIPV	FIPV	NNP
cord-256444-grw5s2pf	1491	42	peplomer	peplomer	NNP
cord-256444-grw5s2pf	1491	43	protein	protein	NN
cord-256444-grw5s2pf	1491	44	induces	induce	VBZ
cord-256444-grw5s2pf	1491	45	cell	cell	NN
cord-256444-grw5s2pf	1491	46	fusion	fusion	NN
cord-256444-grw5s2pf	1491	47	and	and	CC
cord-256444-grw5s2pf	1491	48	elicits	elicit	VBZ
cord-256444-grw5s2pf	1491	49	neutralizing	neutralize	VBG
cord-256444-grw5s2pf	1491	50	antibodies	antibody	NNS
cord-256444-grw5s2pf	1491	51	in	in	IN
cord-256444-grw5s2pf	1491	52	mice	mouse	NNS
cord-256444-grw5s2pf	1492	1	Sindbis	Sindbis	NNP
cord-256444-grw5s2pf	1492	2	virus	virus	NN
cord-256444-grw5s2pf	1492	3	RNA	rna	NN
cord-256444-grw5s2pf	1492	4	polymerase	polymerase	NN
cord-256444-grw5s2pf	1492	5	is	be	VBZ
cord-256444-grw5s2pf	1492	6	degraded	degrade	VBN
cord-256444-grw5s2pf	1492	7	by	by	IN
cord-256444-grw5s2pf	1492	8	the	the	DT
cord-256444-grw5s2pf	1492	9	N	n	CD
cord-256444-grw5s2pf	1492	10	-	-	HYPH
cord-256444-grw5s2pf	1492	11	end	end	NN
cord-256444-grw5s2pf	1492	12	rule	rule	NN
cord-256444-grw5s2pf	1492	13	pathway	pathway	NN
cord-256444-grw5s2pf	1492	14	The	the	DT
cord-256444-grw5s2pf	1492	15	fitness	fitness	NN
cord-256444-grw5s2pf	1492	16	of	of	IN
cord-256444-grw5s2pf	1492	17	defective	defective	JJ
cord-256444-grw5s2pf	1492	18	interfering	interfere	VBG
cord-256444-grw5s2pf	1492	19	murine	murine	JJ
cord-256444-grw5s2pf	1492	20	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1492	21	DI	di	NN
cord-256444-grw5s2pf	1492	22	-	-	,
cord-256444-grw5s2pf	1492	23	a	a	NN
cord-256444-grw5s2pf	1492	24	and	and	CC
cord-256444-grw5s2pf	1492	25	its	-PRON-	PRP$
cord-256444-grw5s2pf	1492	26	derivatives	derivative	NNS
cord-256444-grw5s2pf	1492	27	is	be	VBZ
cord-256444-grw5s2pf	1492	28	decreased	decrease	VBN
cord-256444-grw5s2pf	1492	29	by	by	IN
cord-256444-grw5s2pf	1492	30	nonsense	nonsense	NN
cord-256444-grw5s2pf	1492	31	and	and	CC
cord-256444-grw5s2pf	1492	32	frameshift	frameshift	NN
cord-256444-grw5s2pf	1492	33	mutations	mutation	NNS
cord-256444-grw5s2pf	1492	34	Assembly	Assembly	NNP
cord-256444-grw5s2pf	1492	35	of	of	IN
cord-256444-grw5s2pf	1492	36	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1492	37	spike	spike	NN
cord-256444-grw5s2pf	1492	38	protein	protein	NN
cord-256444-grw5s2pf	1492	39	into	into	IN
cord-256444-grw5s2pf	1492	40	trimers	trimer	NNS
cord-256444-grw5s2pf	1492	41	and	and	CC
cord-256444-grw5s2pf	1492	42	its	-PRON-	PRP$
cord-256444-grw5s2pf	1492	43	role	role	NN
cord-256444-grw5s2pf	1492	44	in	in	IN
cord-256444-grw5s2pf	1492	45	epitope	epitope	NN
cord-256444-grw5s2pf	1492	46	expression	expression	NN
cord-256444-grw5s2pf	1493	1	Aminopeptidase	Aminopeptidase	NNP
cord-256444-grw5s2pf	1493	2	N	N	NNP
cord-256444-grw5s2pf	1493	3	is	be	VBZ
cord-256444-grw5s2pf	1493	4	a	a	DT
cord-256444-grw5s2pf	1493	5	major	major	JJ
cord-256444-grw5s2pf	1493	6	receptor	receptor	NN
cord-256444-grw5s2pf	1493	7	for	for	IN
cord-256444-grw5s2pf	1493	8	the	the	DT
cord-256444-grw5s2pf	1493	9	entero	entero	NNP
cord-256444-grw5s2pf	1493	10	-	-	HYPH
cord-256444-grw5s2pf	1493	11	pathogenic	pathogenic	JJ
cord-256444-grw5s2pf	1493	12	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1493	13	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1493	14	Determinants	determinant	NNS
cord-256444-grw5s2pf	1493	15	essential	essential	JJ
cord-256444-grw5s2pf	1493	16	for	for	IN
cord-256444-grw5s2pf	1493	17	the	the	DT
cord-256444-grw5s2pf	1493	18	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1493	19	gastroenteritis	gastroenteritis	JJ
cord-256444-grw5s2pf	1493	20	virus	virus	NN
cord-256444-grw5s2pf	1493	21	-	-	HYPH
cord-256444-grw5s2pf	1493	22	receptor	receptor	NN
cord-256444-grw5s2pf	1493	23	interaction	interaction	NN
cord-256444-grw5s2pf	1493	24	reside	reside	VBP
cord-256444-grw5s2pf	1493	25	within	within	IN
cord-256444-grw5s2pf	1493	26	a	a	DT
cord-256444-grw5s2pf	1493	27	domain	domain	NN
cord-256444-grw5s2pf	1493	28	of	of	IN
cord-256444-grw5s2pf	1493	29	aminopeptidase	aminopeptidase	NN
cord-256444-grw5s2pf	1493	30	-	-	HYPH
cord-256444-grw5s2pf	1493	31	N	n	NN
cord-256444-grw5s2pf	1493	32	that	that	WDT
cord-256444-grw5s2pf	1493	33	is	be	VBZ
cord-256444-grw5s2pf	1493	34	distinct	distinct	JJ
cord-256444-grw5s2pf	1493	35	from	from	IN
cord-256444-grw5s2pf	1493	36	the	the	DT
cord-256444-grw5s2pf	1493	37	enzymatic	enzymatic	JJ
cord-256444-grw5s2pf	1493	38	site	site	NN
cord-256444-grw5s2pf	1493	39	Equine	equine	JJ
cord-256444-grw5s2pf	1493	40	arteritis	arteritis	NN
cord-256444-grw5s2pf	1493	41	virus	virus	NN
cord-256444-grw5s2pf	1493	42	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1493	43	RNA	RNA	NNP
cord-256444-grw5s2pf	1493	44	transcription	transcription	NN
cord-256444-grw5s2pf	1493	45	:	:	:
cord-256444-grw5s2pf	1494	1	W	w	NN
cord-256444-grw5s2pf	1494	2	inactivation	inactivation	NN
cord-256444-grw5s2pf	1494	3	and	and	CC
cord-256444-grw5s2pf	1494	4	translation	translation	NN
cord-256444-grw5s2pf	1494	5	inhibition	inhibition	NN
cord-256444-grw5s2pf	1494	6	studies	study	NNS
cord-256444-grw5s2pf	1494	7	Translation	translation	NN
cord-256444-grw5s2pf	1494	8	and	and	CC
cord-256444-grw5s2pf	1494	9	processing	processing	NN
cord-256444-grw5s2pf	1494	10	of	of	IN
cord-256444-grw5s2pf	1494	11	mouse	mouse	NN
cord-256444-grw5s2pf	1494	12	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1494	13	virus	virus	NN
cord-256444-grw5s2pf	1494	14	virion	virion	NN
cord-256444-grw5s2pf	1494	15	RNA	RNA	NNP
cord-256444-grw5s2pf	1494	16	in	in	IN
cord-256444-grw5s2pf	1494	17	a	a	DT
cord-256444-grw5s2pf	1494	18	cell	cell	NN
cord-256444-grw5s2pf	1494	19	-	-	HYPH
cord-256444-grw5s2pf	1494	20	free	free	JJ
cord-256444-grw5s2pf	1494	21	system	system	NN
cord-256444-grw5s2pf	1495	1	Intracellular	Intracellular	NNP
cord-256444-grw5s2pf	1495	2	processing	processing	NN
cord-256444-grw5s2pf	1495	3	of	of	IN
cord-256444-grw5s2pf	1495	4	the	the	DT
cord-256444-grw5s2pf	1495	5	N	n	CD
cord-256444-grw5s2pf	1495	6	-	-	HYPH
cord-256444-grw5s2pf	1495	7	terminal	terminal	NN
cord-256444-grw5s2pf	1495	8	ORF	ORF	NNP
cord-256444-grw5s2pf	1495	9	l	l	NN
cord-256444-grw5s2pf	1496	1	a	a	DT
cord-256444-grw5s2pf	1496	2	proteins	protein	NNS
cord-256444-grw5s2pf	1496	3	of	of	IN
cord-256444-grw5s2pf	1496	4	the	the	DT
cord-256444-grw5s2pf	1496	5	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1496	6	MHV	MHV	NNP
cord-256444-grw5s2pf	1496	7	-	-	HYPH
cord-256444-grw5s2pf	1496	8	A59	A59	NNP
cord-256444-grw5s2pf	1496	9	requires	require	VBZ
cord-256444-grw5s2pf	1496	10	multiple	multiple	JJ
cord-256444-grw5s2pf	1496	11	proteolytic	proteolytic	JJ
cord-256444-grw5s2pf	1496	12	events	event	NNS
cord-256444-grw5s2pf	1496	13	Identification	identification	NN
cord-256444-grw5s2pf	1496	14	and	and	CC
cord-256444-grw5s2pf	1496	15	characterization	characterization	NN
cord-256444-grw5s2pf	1496	16	of	of	IN
cord-256444-grw5s2pf	1496	17	a	a	DT
cord-256444-grw5s2pf	1496	18	65-kDa	65-kda	CD
cord-256444-grw5s2pf	1496	19	protein	protein	NN
cord-256444-grw5s2pf	1496	20	processed	process	VBN
cord-256444-grw5s2pf	1496	21	from	from	IN
cord-256444-grw5s2pf	1496	22	the	the	DT
cord-256444-grw5s2pf	1496	23	gene	gene	NN
cord-256444-grw5s2pf	1496	24	1	1	CD
cord-256444-grw5s2pf	1496	25	polyprotein	polyprotein	NN
cord-256444-grw5s2pf	1496	26	of	of	IN
cord-256444-grw5s2pf	1496	27	the	the	DT
cord-256444-grw5s2pf	1496	28	murine	murine	JJ
cord-256444-grw5s2pf	1496	29	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1496	30	MHV	MHV	NNP
cord-256444-grw5s2pf	1496	31	-	-	HYPH
cord-256444-grw5s2pf	1496	32	A59	A59	NNP
cord-256444-grw5s2pf	1496	33	RNA	RNA	NNP
cord-256444-grw5s2pf	1496	34	-	-	HYPH
cord-256444-grw5s2pf	1496	35	dependent	dependent	JJ
cord-256444-grw5s2pf	1496	36	RNA	RNA	NNP
cord-256444-grw5s2pf	1496	37	polymerase	polymerase	NN
cord-256444-grw5s2pf	1496	38	activity	activity	NN
cord-256444-grw5s2pf	1496	39	in	in	IN
cord-256444-grw5s2pf	1496	40	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1496	41	-	-	HYPH
cord-256444-grw5s2pf	1496	42	infected	infect	VBN
cord-256444-grw5s2pf	1496	43	cells	cell	NNS
cord-256444-grw5s2pf	1496	44	Monoclonal	monoclonal	JJ
cord-256444-grw5s2pf	1496	45	antibodies	antibody	NNS
cord-256444-grw5s2pf	1496	46	to	to	IN
cord-256444-grw5s2pf	1496	47	bovine	bovine	JJ
cord-256444-grw5s2pf	1496	48	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1496	49	:	:	:
cord-256444-grw5s2pf	1496	50	Characteristics	characteristic	NNS
cord-256444-grw5s2pf	1496	51	and	and	CC
cord-256444-grw5s2pf	1496	52	topographical	topographical	JJ
cord-256444-grw5s2pf	1496	53	mapping	mapping	NN
cord-256444-grw5s2pf	1496	54	of	of	IN
cord-256444-grw5s2pf	1496	55	neutralizing	neutralize	VBG
cord-256444-grw5s2pf	1496	56	epitopes	epitope	NNS
cord-256444-grw5s2pf	1496	57	on	on	IN
cord-256444-grw5s2pf	1496	58	the	the	DT
cord-256444-grw5s2pf	1496	59	E2	E2	NNP
cord-256444-grw5s2pf	1496	60	and	and	CC
cord-256444-grw5s2pf	1496	61	E3	e3	NN
cord-256444-grw5s2pf	1496	62	glycoproteins	glycoprotein	NNS
cord-256444-grw5s2pf	1496	63	Monoclonal	monoclonal	JJ
cord-256444-grw5s2pf	1496	64	antibodies	antibody	NNS
cord-256444-grw5s2pf	1496	65	to	to	IN
cord-256444-grw5s2pf	1496	66	bovine	bovine	JJ
cord-256444-grw5s2pf	1496	67	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1496	68	glycoproteins	glycoprotein	NNS
cord-256444-grw5s2pf	1496	69	E2	E2	NNP
cord-256444-grw5s2pf	1496	70	and	and	CC
cord-256444-grw5s2pf	1496	71	E3	E3	NNP
cord-256444-grw5s2pf	1496	72	:	:	:
cord-256444-grw5s2pf	1497	1	Demonstration	demonstration	NN
cord-256444-grw5s2pf	1497	2	of	of	IN
cord-256444-grw5s2pf	1497	3	in	in	IN
cord-256444-grw5s2pf	1497	4	vivo	vivo	FW
cord-256444-grw5s2pf	1497	5	neutralizing	neutralize	VBG
cord-256444-grw5s2pf	1497	6	activity	activity	NN
cord-256444-grw5s2pf	1497	7	Determinants	determinant	NNS
cord-256444-grw5s2pf	1497	8	of	of	IN
cord-256444-grw5s2pf	1497	9	the	the	DT
cord-256444-grw5s2pf	1497	10	p28	p28	CD
cord-256444-grw5s2pf	1497	11	cleavage	cleavage	NN
cord-256444-grw5s2pf	1497	12	site	site	NN
cord-256444-grw5s2pf	1497	13	recognized	recognize	VBN
cord-256444-grw5s2pf	1497	14	by	by	IN
cord-256444-grw5s2pf	1497	15	the	the	DT
cord-256444-grw5s2pf	1497	16	first	first	JJ
cord-256444-grw5s2pf	1497	17	papain	papain	NN
cord-256444-grw5s2pf	1497	18	-	-	HYPH
cord-256444-grw5s2pf	1497	19	like	like	JJ
cord-256444-grw5s2pf	1497	20	cysteine	cysteine	NN
cord-256444-grw5s2pf	1497	21	proteinase	proteinase	NN
cord-256444-grw5s2pf	1497	22	of	of	IN
cord-256444-grw5s2pf	1497	23	murine	murine	JJ
cord-256444-grw5s2pf	1497	24	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1497	25	Morphology	morphology	NN
cord-256444-grw5s2pf	1497	26	and	and	CC
cord-256444-grw5s2pf	1497	27	morphogenesis	morphogenesis	NN
cord-256444-grw5s2pf	1497	28	of	of	IN
cord-256444-grw5s2pf	1497	29	a	a	DT
cord-256444-grw5s2pf	1497	30	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1497	31	infecting	infect	VBG
cord-256444-grw5s2pf	1497	32	intestinal	intestinal	JJ
cord-256444-grw5s2pf	1497	33	epithelial	epithelial	JJ
cord-256444-grw5s2pf	1497	34	cells	cell	NNS
cord-256444-grw5s2pf	1497	35	of	of	IN
cord-256444-grw5s2pf	1497	36	newborn	newborn	JJ
cord-256444-grw5s2pf	1497	37	calves	calf	NNS
cord-256444-grw5s2pf	1497	38	Sequence	sequence	NN
cord-256444-grw5s2pf	1497	39	analysis	analysis	NN
cord-256444-grw5s2pf	1497	40	of	of	IN
cord-256444-grw5s2pf	1497	41	the	the	DT
cord-256444-grw5s2pf	1497	42	porcine	porcine	JJ
cord-256444-grw5s2pf	1497	43	epidemic	epidemic	NN
cord-256444-grw5s2pf	1497	44	diarrhea	diarrhea	NN
cord-256444-grw5s2pf	1497	45	virus	virus	NN
cord-256444-grw5s2pf	1497	46	genome	genome	NN
cord-256444-grw5s2pf	1497	47	between	between	IN
cord-256444-grw5s2pf	1497	48	the	the	DT
cord-256444-grw5s2pf	1497	49	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1497	50	and	and	CC
cord-256444-grw5s2pf	1497	51	spike	spike	NN
cord-256444-grw5s2pf	1497	52	protein	protein	NN
cord-256444-grw5s2pf	1497	53	genes	gene	NNS
cord-256444-grw5s2pf	1497	54	reveals	reveal	VBZ
cord-256444-grw5s2pf	1497	55	a	a	DT
cord-256444-grw5s2pf	1497	56	polymorphic	polymorphic	JJ
cord-256444-grw5s2pf	1497	57	ORF	ORF	NNP
cord-256444-grw5s2pf	1497	58	Cell	Cell	NNP
cord-256444-grw5s2pf	1497	59	tropism	tropism	NN
cord-256444-grw5s2pf	1497	60	and	and	CC
cord-256444-grw5s2pf	1497	61	expression	expression	NN
cord-256444-grw5s2pf	1497	62	of	of	IN
cord-256444-grw5s2pf	1497	63	mouse	mouse	NN
cord-256444-grw5s2pf	1497	64	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1497	65	viruses	virus	NNS
cord-256444-grw5s2pf	1497	66	(	(	-LRB-
cord-256444-grw5s2pf	1497	67	MHV	MHV	NNP
cord-256444-grw5s2pf	1497	68	)	)	-RRB-
cord-256444-grw5s2pf	1497	69	in	in	IN
cord-256444-grw5s2pf	1497	70	mouse	mouse	NN
cord-256444-grw5s2pf	1497	71	spinal	spinal	JJ
cord-256444-grw5s2pf	1497	72	cord	cord	NN
cord-256444-grw5s2pf	1497	73	cultures	culture	NNS
cord-256444-grw5s2pf	1497	74	Genetically	genetically	RB
cord-256444-grw5s2pf	1497	75	-	-	HYPH
cord-256444-grw5s2pf	1497	76	determined	determine	VBN
cord-256444-grw5s2pf	1497	77	sensitivity	sensitivity	NN
cord-256444-grw5s2pf	1497	78	to	to	IN
cord-256444-grw5s2pf	1497	79	MHV3	MHV3	NNP
cord-256444-grw5s2pf	1497	80	infections	infection	NNS
cord-256444-grw5s2pf	1497	81	is	be	VBZ
cord-256444-grw5s2pf	1497	82	expressed	express	VBN
cord-256444-grw5s2pf	1497	83	in	in	IN
cord-256444-grw5s2pf	1497	84	vitro	vitro	FW
cord-256444-grw5s2pf	1497	85	in	in	IN
cord-256444-grw5s2pf	1497	86	lymphoid	lymphoid	JJ
cord-256444-grw5s2pf	1497	87	cells	cell	NNS
cord-256444-grw5s2pf	1497	88	and	and	CC
cord-256444-grw5s2pf	1497	89	macrophages	macrophage	NNS
cord-256444-grw5s2pf	1497	90	Cloning	clone	VBG
cord-256444-grw5s2pf	1497	91	of	of	IN
cord-256444-grw5s2pf	1497	92	the	the	DT
cord-256444-grw5s2pf	1497	93	mouse	mouse	NN
cord-256444-grw5s2pf	1497	94	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1497	95	virus	virus	NN
cord-256444-grw5s2pf	1497	96	(	(	-LRB-
cord-256444-grw5s2pf	1497	97	MHV	mhv	NN
cord-256444-grw5s2pf	1497	98	)	)	-RRB-
cord-256444-grw5s2pf	1497	99	receptor	receptor	NN
cord-256444-grw5s2pf	1497	100	:	:	:
cord-256444-grw5s2pf	1497	101	Expression	expression	NN
cord-256444-grw5s2pf	1497	102	in	in	IN
cord-256444-grw5s2pf	1497	103	human	human	JJ
cord-256444-grw5s2pf	1497	104	and	and	CC
cord-256444-grw5s2pf	1497	105	hamster	hamster	NN
cord-256444-grw5s2pf	1497	106	cell	cell	NN
cord-256444-grw5s2pf	1497	107	lines	line	NNS
cord-256444-grw5s2pf	1497	108	confers	confer	VBZ
cord-256444-grw5s2pf	1497	109	susceptibility	susceptibility	NN
cord-256444-grw5s2pf	1497	110	to	to	IN
cord-256444-grw5s2pf	1497	111	MHV	MHV	NNP
cord-256444-grw5s2pf	1497	112	Several	several	JJ
cord-256444-grw5s2pf	1497	113	members	member	NNS
cord-256444-grw5s2pf	1497	114	of	of	IN
cord-256444-grw5s2pf	1497	115	the	the	DT
cord-256444-grw5s2pf	1497	116	mouse	mouse	NN
cord-256444-grw5s2pf	1497	117	carcinoembryonic	carcinoembryonic	NNP
cord-256444-grw5s2pf	1497	118	antigen	antigen	NN
cord-256444-grw5s2pf	1497	119	-	-	HYPH
cord-256444-grw5s2pf	1497	120	related	relate	VBN
cord-256444-grw5s2pf	1497	121	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1497	122	family	family	NN
cord-256444-grw5s2pf	1497	123	are	be	VBP
cord-256444-grw5s2pf	1497	124	functional	functional	JJ
cord-256444-grw5s2pf	1497	125	receptors	receptor	NNS
cord-256444-grw5s2pf	1497	126	for	for	IN
cord-256444-grw5s2pf	1497	127	the	the	DT
cord-256444-grw5s2pf	1497	128	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1497	129	mouse	mouse	NN
cord-256444-grw5s2pf	1497	130	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1497	131	virus	virus	NN
cord-256444-grw5s2pf	1497	132	-	-	:
cord-256444-grw5s2pf	1497	133	A59	A59	NNP
cord-256444-grw5s2pf	1497	134	Mouse	Mouse	NNP
cord-256444-grw5s2pf	1497	135	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1497	136	virus	virus	NN
cord-256444-grw5s2pf	1497	137	strain	strain	VBP
cord-256444-grw5s2pf	1497	138	A59	A59	NNP
cord-256444-grw5s2pf	1497	139	and	and	CC
cord-256444-grw5s2pf	1497	140	blocking	block	VBG
cord-256444-grw5s2pf	1497	141	antireceptor	antireceptor	NN
cord-256444-grw5s2pf	1497	142	monoclonal	monoclonal	JJ
cord-256444-grw5s2pf	1497	143	antibody	antibody	NN
cord-256444-grw5s2pf	1497	144	bind	bind	VB
cord-256444-grw5s2pf	1497	145	to	to	IN
cord-256444-grw5s2pf	1497	146	the	the	DT
cord-256444-grw5s2pf	1497	147	N	n	CD
cord-256444-grw5s2pf	1497	148	-	-	HYPH
cord-256444-grw5s2pf	1497	149	terminal	terminal	NN
cord-256444-grw5s2pf	1497	150	domain	domain	NN
cord-256444-grw5s2pf	1497	151	of	of	IN
cord-256444-grw5s2pf	1497	152	cellular	cellular	JJ
cord-256444-grw5s2pf	1497	153	receptor	receptor	NN
cord-256444-grw5s2pf	1497	154	Mouse	Mouse	NNP
cord-256444-grw5s2pf	1497	155	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1497	156	virus	virus	NN
cord-256444-grw5s2pf	1497	157	receptor	receptor	NN
cord-256444-grw5s2pf	1497	158	activities	activity	NNS
cord-256444-grw5s2pf	1497	159	of	of	IN
cord-256444-grw5s2pf	1497	160	an	an	DT
cord-256444-grw5s2pf	1497	161	MHVWmph	mhvwmph	NN
cord-256444-grw5s2pf	1497	162	chimera	chimera	NN
cord-256444-grw5s2pf	1497	163	and	and	CC
cord-256444-grw5s2pf	1497	164	MHVR	MHVR	NNP
cord-256444-grw5s2pf	1497	165	mutants	mutant	NNS
cord-256444-grw5s2pf	1497	166	lacking	lack	VBG
cord-256444-grw5s2pf	1497	167	N	n	CD
cord-256444-grw5s2pf	1497	168	-	-	HYPH
cord-256444-grw5s2pf	1497	169	linked	link	VBN
cord-256444-grw5s2pf	1497	170	glycosylation	glycosylation	NN
cord-256444-grw5s2pf	1497	171	of	of	IN
cord-256444-grw5s2pf	1497	172	the	the	DT
cord-256444-grw5s2pf	1497	173	N	n	CD
cord-256444-grw5s2pf	1497	174	-	-	HYPH
cord-256444-grw5s2pf	1497	175	terminal	terminal	NN
cord-256444-grw5s2pf	1497	176	domain	domain	NN
cord-256444-grw5s2pf	1497	177	Identification	identification	NN
cord-256444-grw5s2pf	1497	178	of	of	IN
cord-256444-grw5s2pf	1497	179	the	the	DT
cord-256444-grw5s2pf	1497	180	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1497	181	MHV	MHV	NNP
cord-256444-grw5s2pf	1497	182	-	-	HYPH
cord-256444-grw5s2pf	1497	183	JHM	JHM	NNP
cord-256444-grw5s2pf	1497	184	mRNA	mrna	NN
cord-256444-grw5s2pf	1497	185	4	4	CD
cord-256444-grw5s2pf	1497	186	product	product	NN
cord-256444-grw5s2pf	1497	187	Complete	complete	JJ
cord-256444-grw5s2pf	1497	188	sequence	sequence	NN
cord-256444-grw5s2pf	1497	189	(	(	-LRB-
cord-256444-grw5s2pf	1497	190	20	20	CD
cord-256444-grw5s2pf	1497	191	kilobases	kilobase	NNS
cord-256444-grw5s2pf	1497	192	)	)	-RRB-
cord-256444-grw5s2pf	1497	193	of	of	IN
cord-256444-grw5s2pf	1497	194	the	the	DT
cord-256444-grw5s2pf	1497	195	polyprotein	polyprotein	JJ
cord-256444-grw5s2pf	1497	196	-	-	HYPH
cord-256444-grw5s2pf	1497	197	encoding	encode	VBG
cord-256444-grw5s2pf	1497	198	gene	gene	NN
cord-256444-grw5s2pf	1497	199	1	1	CD
cord-256444-grw5s2pf	1497	200	of	of	IN
cord-256444-grw5s2pf	1497	201	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1497	202	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1497	203	virus	virus	NN
cord-256444-grw5s2pf	1497	204	Molecular	molecular	JJ
cord-256444-grw5s2pf	1497	205	basis	basis	NN
cord-256444-grw5s2pf	1497	206	of	of	IN
cord-256444-grw5s2pf	1497	207	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1497	208	gastroenteritis	gastroenteritis	JJ
cord-256444-grw5s2pf	1497	209	virus	virus	NN
cord-256444-grw5s2pf	1497	210	epidemiology	epidemiology	NN
cord-256444-grw5s2pf	1498	1	The	the	DT
cord-256444-grw5s2pf	1498	2	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1498	3	avian	avian	JJ
cord-256444-grw5s2pf	1498	4	infectious	infectious	JJ
cord-256444-grw5s2pf	1498	5	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1498	6	virus	virus	NN
cord-256444-grw5s2pf	1498	7	requires	require	VBZ
cord-256444-grw5s2pf	1498	8	the	the	DT
cord-256444-grw5s2pf	1498	9	cell	cell	NN
cord-256444-grw5s2pf	1498	10	nucleus	nucleus	NN
cord-256444-grw5s2pf	1498	11	and	and	CC
cord-256444-grw5s2pf	1498	12	host	host	NN
cord-256444-grw5s2pf	1498	13	transcriptional	transcriptional	JJ
cord-256444-grw5s2pf	1498	14	factors	factor	NNS
cord-256444-grw5s2pf	1499	1	The	the	DT
cord-256444-grw5s2pf	1499	2	internal	internal	JJ
cord-256444-grw5s2pf	1499	3	open	open	JJ
cord-256444-grw5s2pf	1499	4	reading	reading	NN
cord-256444-grw5s2pf	1499	5	frame	frame	NN
cord-256444-grw5s2pf	1499	6	within	within	IN
cord-256444-grw5s2pf	1499	7	the	the	DT
cord-256444-grw5s2pf	1499	8	nucleocapsid	nucleocapsid	NNP
cord-256444-grw5s2pf	1499	9	gene	gene	NN
cord-256444-grw5s2pf	1499	10	of	of	IN
cord-256444-grw5s2pf	1499	11	mouse	mouse	NNP
cord-256444-grw5s2pf	1499	12	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1499	13	virus	virus	NN
cord-256444-grw5s2pf	1499	14	encodes	encode	VBZ
cord-256444-grw5s2pf	1499	15	a	a	DT
cord-256444-grw5s2pf	1499	16	structural	structural	JJ
cord-256444-grw5s2pf	1499	17	protein	protein	NN
cord-256444-grw5s2pf	1499	18	that	that	WDT
cord-256444-grw5s2pf	1499	19	is	be	VBZ
cord-256444-grw5s2pf	1499	20	not	not	RB
cord-256444-grw5s2pf	1499	21	essential	essential	JJ
cord-256444-grw5s2pf	1499	22	for	for	IN
cord-256444-grw5s2pf	1499	23	viral	viral	JJ
cord-256444-grw5s2pf	1499	24	replication	replication	NN
cord-256444-grw5s2pf	1499	25	Pathogenicity	Pathogenicity	NNP
cord-256444-grw5s2pf	1499	26	of	of	IN
cord-256444-grw5s2pf	1499	27	antigenic	antigenic	JJ
cord-256444-grw5s2pf	1499	28	variants	variant	NNS
cord-256444-grw5s2pf	1499	29	of	of	IN
cord-256444-grw5s2pf	1499	30	murine	murine	JJ
cord-256444-grw5s2pf	1499	31	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1499	32	JHM	JHM	NNP
cord-256444-grw5s2pf	1499	33	selected	select	VBN
cord-256444-grw5s2pf	1499	34	with	with	IN
cord-256444-grw5s2pf	1499	35	monoclonal	monoclonal	JJ
cord-256444-grw5s2pf	1499	36	antibodies	antibody	NNS
cord-256444-grw5s2pf	1499	37	Experimental	experimental	JJ
cord-256444-grw5s2pf	1499	38	demyelination	demyelination	NN
cord-256444-grw5s2pf	1499	39	induced	induce	VBN
cord-256444-grw5s2pf	1499	40	by	by	IN
cord-256444-grw5s2pf	1499	41	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1499	42	JHM	JHM	NNP
cord-256444-grw5s2pf	1499	43	(	(	-LRB-
cord-256444-grw5s2pf	1499	44	MHV-4	MHV-4	NNP
cord-256444-grw5s2pf	1499	45	)	)	-RRB-
cord-256444-grw5s2pf	1499	46	:	:	:
cord-256444-grw5s2pf	1500	1	Molecular	molecular	JJ
cord-256444-grw5s2pf	1500	2	identification	identification	NN
cord-256444-grw5s2pf	1500	3	of	of	IN
cord-256444-grw5s2pf	1500	4	a	a	DT
cord-256444-grw5s2pf	1500	5	viral	viral	JJ
cord-256444-grw5s2pf	1500	6	determinant	determinant	NN
cord-256444-grw5s2pf	1500	7	of	of	IN
cord-256444-grw5s2pf	1500	8	paralytic	paralytic	JJ
cord-256444-grw5s2pf	1500	9	disease	disease	NN
cord-256444-grw5s2pf	1500	10	Replication	replication	NN
cord-256444-grw5s2pf	1500	11	of	of	IN
cord-256444-grw5s2pf	1500	12	murine	murine	JJ
cord-256444-grw5s2pf	1500	13	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1500	14	in	in	IN
cord-256444-grw5s2pf	1500	15	somatic	somatic	JJ
cord-256444-grw5s2pf	1500	16	cell	cell	NN
cord-256444-grw5s2pf	1500	17	hybrids	hybrid	NNS
cord-256444-grw5s2pf	1500	18	between	between	IN
cord-256444-grw5s2pf	1500	19	murine	murine	JJ
cord-256444-grw5s2pf	1500	20	fibroblasts	fibroblast	NNS
cord-256444-grw5s2pf	1500	21	and	and	CC
cord-256444-grw5s2pf	1500	22	rat	rat	NN
cord-256444-grw5s2pf	1500	23	schwannoma	schwannoma	FW
cord-256444-grw5s2pf	1500	24	cells	cell	VBZ
cord-256444-grw5s2pf	1500	25	Identification	identification	NN
cord-256444-grw5s2pf	1500	26	and	and	CC
cord-256444-grw5s2pf	1500	27	characterization	characterization	NN
cord-256444-grw5s2pf	1500	28	of	of	IN
cord-256444-grw5s2pf	1500	29	a	a	DT
cord-256444-grw5s2pf	1500	30	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1500	31	packaging	packaging	NN
cord-256444-grw5s2pf	1500	32	signal	signal	NN
cord-256444-grw5s2pf	1500	33	Proteolytic	proteolytic	JJ
cord-256444-grw5s2pf	1500	34	cleavage	cleavage	NN
cord-256444-grw5s2pf	1500	35	of	of	IN
cord-256444-grw5s2pf	1500	36	the	the	DT
cord-256444-grw5s2pf	1500	37	E2	E2	NNP
cord-256444-grw5s2pf	1500	38	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1500	39	of	of	IN
cord-256444-grw5s2pf	1500	40	murine	murine	JJ
cord-256444-grw5s2pf	1500	41	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1500	42	:	:	:
cord-256444-grw5s2pf	1500	43	Host	host	NN
cord-256444-grw5s2pf	1500	44	-	-	HYPH
cord-256444-grw5s2pf	1500	45	dependent	dependent	JJ
cord-256444-grw5s2pf	1500	46	differences	difference	NNS
cord-256444-grw5s2pf	1500	47	in	in	IN
cord-256444-grw5s2pf	1500	48	proteolytic	proteolytic	JJ
cord-256444-grw5s2pf	1500	49	cleavage	cleavage	NN
cord-256444-grw5s2pf	1500	50	and	and	CC
cord-256444-grw5s2pf	1500	51	cell	cell	NN
cord-256444-grw5s2pf	1500	52	fusion	fusion	NN
cord-256444-grw5s2pf	1500	53	Evidence	evidence	NN
cord-256444-grw5s2pf	1500	54	for	for	IN
cord-256444-grw5s2pf	1500	55	variable	variable	JJ
cord-256444-grw5s2pf	1500	56	rates	rate	NNS
cord-256444-grw5s2pf	1500	57	of	of	IN
cord-256444-grw5s2pf	1500	58	recombination	recombination	NN
cord-256444-grw5s2pf	1500	59	in	in	IN
cord-256444-grw5s2pf	1500	60	the	the	DT
cord-256444-grw5s2pf	1500	61	MHV	MHV	NNP
cord-256444-grw5s2pf	1500	62	genome	genome	NN
cord-256444-grw5s2pf	1500	63	Map	Map	NNP
cord-256444-grw5s2pf	1500	64	locations	location	NNS
cord-256444-grw5s2pf	1500	65	of	of	IN
cord-256444-grw5s2pf	1500	66	mouse	mouse	NNP
cord-256444-grw5s2pf	1500	67	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1500	68	virus	virus	NN
cord-256444-grw5s2pf	1500	69	temperaturesensitive	temperaturesensitive	NNP
cord-256444-grw5s2pf	1500	70	mutants	mutant	NNS
cord-256444-grw5s2pf	1500	71	:	:	:
cord-256444-grw5s2pf	1501	1	Confirmation	confirmation	NN
cord-256444-grw5s2pf	1501	2	of	of	IN
cord-256444-grw5s2pf	1501	3	variable	variable	JJ
cord-256444-grw5s2pf	1501	4	rates	rate	NNS
cord-256444-grw5s2pf	1501	5	of	of	IN
cord-256444-grw5s2pf	1501	6	recombination	recombination	NN
cord-256444-grw5s2pf	1501	7	Three	three	CD
cord-256444-grw5s2pf	1501	8	different	different	JJ
cord-256444-grw5s2pf	1501	9	cellular	cellular	JJ
cord-256444-grw5s2pf	1501	10	proteins	protein	NNS
cord-256444-grw5s2pf	1501	11	bind	bind	VBP
cord-256444-grw5s2pf	1501	12	to	to	IN
cord-256444-grw5s2pf	1501	13	the	the	DT
cord-256444-grw5s2pf	1501	14	complementary	complementary	JJ
cord-256444-grw5s2pf	1501	15	sites	site	NNS
cord-256444-grw5s2pf	1501	16	on	on	IN
cord-256444-grw5s2pf	1501	17	the	the	DT
cord-256444-grw5s2pf	1501	18	5'-end	5'-end	CD
cord-256444-grw5s2pf	1501	19	positive	positive	JJ
cord-256444-grw5s2pf	1501	20	-	-	HYPH
cord-256444-grw5s2pf	1501	21	and	and	CC
cord-256444-grw5s2pf	1501	22	3'-end	3'-end	CD
cord-256444-grw5s2pf	1501	23	negative	negative	JJ
cord-256444-grw5s2pf	1501	24	-	-	HYPH
cord-256444-grw5s2pf	1501	25	strands	strand	NNS
cord-256444-grw5s2pf	1501	26	of	of	IN
cord-256444-grw5s2pf	1501	27	mouse	mouse	NN
cord-256444-grw5s2pf	1501	28	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1501	29	virus	virus	NN
cord-256444-grw5s2pf	1501	30	RNA	RNA	NNP
cord-256444-grw5s2pf	1501	31	Natural	natural	JJ
cord-256444-grw5s2pf	1501	32	evolution	evolution	NN
cord-256444-grw5s2pf	1501	33	of	of	IN
cord-256444-grw5s2pf	1501	34	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1501	35	defective	defective	JJ
cord-256444-grw5s2pf	1501	36	-	-	HYPH
cord-256444-grw5s2pf	1501	37	interfering	interfere	VBG
cord-256444-grw5s2pf	1501	38	RNA	RNA	NNP
cord-256444-grw5s2pf	1501	39	involves	involve	VBZ
cord-256444-grw5s2pf	1501	40	RNA	RNA	NNP
cord-256444-grw5s2pf	1501	41	recombination	recombination	NN
cord-256444-grw5s2pf	1501	42	Interaction	Interaction	NNP
cord-256444-grw5s2pf	1501	43	of	of	IN
cord-256444-grw5s2pf	1501	44	mouse	mouse	NNP
cord-256444-grw5s2pf	1501	45	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1501	46	virus	virus	NN
cord-256444-grw5s2pf	1502	1	(	(	-LRB-
cord-256444-grw5s2pf	1502	2	MHV	MHV	NNP
cord-256444-grw5s2pf	1502	3	)	)	-RRB-
cord-256444-grw5s2pf	1502	4	spike	spike	NN
cord-256444-grw5s2pf	1502	5	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1502	6	with	with	IN
cord-256444-grw5s2pf	1502	7	receptor	receptor	NN
cord-256444-grw5s2pf	1502	8	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1502	9	MHVR	MHVR	NNP
cord-256444-grw5s2pf	1502	10	is	be	VBZ
cord-256444-grw5s2pf	1502	11	required	require	VBN
cord-256444-grw5s2pf	1502	12	for	for	IN
cord-256444-grw5s2pf	1502	13	infection	infection	NN
cord-256444-grw5s2pf	1502	14	with	with	IN
cord-256444-grw5s2pf	1502	15	a	a	DT
cord-256444-grw5s2pf	1502	16	n	n	NN
cord-256444-grw5s2pf	1502	17	MHV	MHV	NNP
cord-256444-grw5s2pf	1502	18	strain	strain	NN
cord-256444-grw5s2pf	1502	19	that	that	WDT
cord-256444-grw5s2pf	1502	20	expresses	express	VBZ
cord-256444-grw5s2pf	1502	21	the	the	DT
cord-256444-grw5s2pf	1502	22	hemagglutinin	hemagglutinin	NN
cord-256444-grw5s2pf	1502	23	-	-	HYPH
cord-256444-grw5s2pf	1502	24	esterase	esterase	NN
cord-256444-grw5s2pf	1502	25	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1502	26	Murine	murine	JJ
cord-256444-grw5s2pf	1502	27	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1502	28	membrane	membrane	NN
cord-256444-grw5s2pf	1502	29	fusion	fusion	NN
cord-256444-grw5s2pf	1502	30	is	be	VBZ
cord-256444-grw5s2pf	1502	31	blocked	block	VBN
cord-256444-grw5s2pf	1502	32	by	by	IN
cord-256444-grw5s2pf	1502	33	modification	modification	NN
cord-256444-grw5s2pf	1502	34	of	of	IN
cord-256444-grw5s2pf	1502	35	thiols	thiol	NNS
cord-256444-grw5s2pf	1502	36	buried	bury	VBN
cord-256444-grw5s2pf	1502	37	within	within	IN
cord-256444-grw5s2pf	1502	38	the	the	DT
cord-256444-grw5s2pf	1502	39	spike	spike	NN
cord-256444-grw5s2pf	1502	40	protein	protein	NN
cord-256444-grw5s2pf	1502	41	Neutralization	neutralization	NN
cord-256444-grw5s2pf	1502	42	-	-	HYPH
cord-256444-grw5s2pf	1502	43	resistant	resistant	JJ
cord-256444-grw5s2pf	1502	44	variants	variant	NNS
cord-256444-grw5s2pf	1502	45	of	of	IN
cord-256444-grw5s2pf	1502	46	a	a	DT
cord-256444-grw5s2pf	1502	47	neurotropic	neurotropic	NNP
cord-256444-grw5s2pf	1502	48	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1502	49	are	be	VBP
cord-256444-grw5s2pf	1502	50	generated	generate	VBN
cord-256444-grw5s2pf	1502	51	by	by	IN
cord-256444-grw5s2pf	1502	52	deletions	deletion	NNS
cord-256444-grw5s2pf	1502	53	within	within	IN
cord-256444-grw5s2pf	1502	54	the	the	DT
cord-256444-grw5s2pf	1502	55	aminoterminal	aminoterminal	JJ
cord-256444-grw5s2pf	1502	56	half	half	NN
cord-256444-grw5s2pf	1502	57	of	of	IN
cord-256444-grw5s2pf	1502	58	the	the	DT
cord-256444-grw5s2pf	1502	59	spike	spike	NN
cord-256444-grw5s2pf	1502	60	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1502	61	Alteration	alteration	NN
cord-256444-grw5s2pf	1502	62	of	of	IN
cord-256444-grw5s2pf	1502	63	the	the	DT
cord-256444-grw5s2pf	1502	64	pH	pH	NNP
cord-256444-grw5s2pf	1502	65	dependence	dependence	NN
cord-256444-grw5s2pf	1502	66	of	of	IN
cord-256444-grw5s2pf	1502	67	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1502	68	-	-	HYPH
cord-256444-grw5s2pf	1502	69	induced	induce	VBN
cord-256444-grw5s2pf	1502	70	cell	cell	NN
cord-256444-grw5s2pf	1502	71	fusion	fusion	NN
cord-256444-grw5s2pf	1502	72	:	:	:
cord-256444-grw5s2pf	1503	1	Effect	effect	NN
cord-256444-grw5s2pf	1503	2	of	of	IN
cord-256444-grw5s2pf	1503	3	mutations	mutation	NNS
cord-256444-grw5s2pf	1503	4	in	in	IN
cord-256444-grw5s2pf	1503	5	the	the	DT
cord-256444-grw5s2pf	1503	6	spike	spike	NN
cord-256444-grw5s2pf	1503	7	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1503	8	Cell	cell	NN
cord-256444-grw5s2pf	1503	9	receptor	receptor	NN
cord-256444-grw5s2pf	1503	10	-	-	HYPH
cord-256444-grw5s2pf	1503	11	independent	independent	JJ
cord-256444-grw5s2pf	1503	12	infection	infection	NN
cord-256444-grw5s2pf	1503	13	by	by	IN
cord-256444-grw5s2pf	1503	14	a	a	DT
cord-256444-grw5s2pf	1503	15	neurotropic	neurotropic	NNP
cord-256444-grw5s2pf	1503	16	murine	murine	JJ
cord-256444-grw5s2pf	1503	17	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1503	18	The	the	DT
cord-256444-grw5s2pf	1503	19	polypeptide	polypeptide	JJ
cord-256444-grw5s2pf	1503	20	structure	structure	NN
cord-256444-grw5s2pf	1503	21	of	of	IN
cord-256444-grw5s2pf	1503	22	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1503	23	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1503	24	virus	virus	NN
cord-256444-grw5s2pf	1503	25	Isolation	isolation	NN
cord-256444-grw5s2pf	1503	26	of	of	IN
cord-256444-grw5s2pf	1503	27	subviral	subviral	JJ
cord-256444-grw5s2pf	1503	28	components	component	NNS
cord-256444-grw5s2pf	1503	29	from	from	IN
cord-256444-grw5s2pf	1503	30	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1503	31	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1503	32	virus	virus	NN
cord-256444-grw5s2pf	1504	1	The	the	DT
cord-256444-grw5s2pf	1504	2	polypeptide	polypeptide	NN
cord-256444-grw5s2pf	1504	3	of	of	IN
cord-256444-grw5s2pf	1504	4	M	M	NNP
cord-256444-grw5s2pf	1504	5	,	,	,
cord-256444-grw5s2pf	1504	6	14,000	14,000	CD
cord-256444-grw5s2pf	1504	7	of	of	IN
cord-256444-grw5s2pf	1504	8	porcine	porcine	JJ
cord-256444-grw5s2pf	1504	9	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1504	10	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1504	11	virus	virus	NN
cord-256444-grw5s2pf	1504	12	:	:	:
cord-256444-grw5s2pf	1504	13	Gene	gene	NN
cord-256444-grw5s2pf	1504	14	assignment	assignment	NN
cord-256444-grw5s2pf	1504	15	and	and	CC
cord-256444-grw5s2pf	1504	16	intracellular	intracellular	JJ
cord-256444-grw5s2pf	1504	17	location	location	NN
cord-256444-grw5s2pf	1504	18	TGEV	tgev	ADD
cord-256444-grw5s2pf	1504	19	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1504	20	ORF4	ORF4	NNP
cord-256444-grw5s2pf	1504	21	encodes	encode	VBZ
cord-256444-grw5s2pf	1504	22	a	a	DT
cord-256444-grw5s2pf	1504	23	membrane	membrane	NN
cord-256444-grw5s2pf	1504	24	protein	protein	NN
cord-256444-grw5s2pf	1504	25	that	that	WDT
cord-256444-grw5s2pf	1504	26	is	be	VBZ
cord-256444-grw5s2pf	1504	27	incorporated	incorporate	VBN
cord-256444-grw5s2pf	1504	28	into	into	IN
cord-256444-grw5s2pf	1504	29	virions	virion	NNS
cord-256444-grw5s2pf	1504	30	Major	major	JJ
cord-256444-grw5s2pf	1504	31	receptor	receptor	NN
cord-256444-grw5s2pf	1504	32	-	-	HYPH
cord-256444-grw5s2pf	1504	33	binding	binding	NN
cord-256444-grw5s2pf	1504	34	and	and	CC
cord-256444-grw5s2pf	1504	35	neutralization	neutralization	NN
cord-256444-grw5s2pf	1504	36	determinants	determinant	NNS
cord-256444-grw5s2pf	1504	37	are	be	VBP
cord-256444-grw5s2pf	1504	38	located	locate	VBN
cord-256444-grw5s2pf	1504	39	within	within	IN
cord-256444-grw5s2pf	1504	40	the	the	DT
cord-256444-grw5s2pf	1504	41	same	same	JJ
cord-256444-grw5s2pf	1504	42	domain	domain	NN
cord-256444-grw5s2pf	1504	43	of	of	IN
cord-256444-grw5s2pf	1504	44	the	the	DT
cord-256444-grw5s2pf	1504	45	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1504	46	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1504	47	virus	virus	NN
cord-256444-grw5s2pf	1504	48	(	(	-LRB-
cord-256444-grw5s2pf	1504	49	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1504	50	)	)	-RRB-
cord-256444-grw5s2pf	1504	51	spike	spike	NN
cord-256444-grw5s2pf	1504	52	protein	protein	NN
cord-256444-grw5s2pf	1504	53	Tissue	tissue	NN
cord-256444-grw5s2pf	1504	54	and	and	CC
cord-256444-grw5s2pf	1504	55	cellular	cellular	JJ
cord-256444-grw5s2pf	1504	56	distribution	distribution	NN
cord-256444-grw5s2pf	1504	57	of	of	IN
cord-256444-grw5s2pf	1504	58	an	an	DT
cord-256444-grw5s2pf	1504	59	adhesion	adhesion	NN
cord-256444-grw5s2pf	1504	60	molecule	molecule	NN
cord-256444-grw5s2pf	1504	61	in	in	IN
cord-256444-grw5s2pf	1504	62	the	the	DT
cord-256444-grw5s2pf	1504	63	carcinoembryonic	carcinoembryonic	NNP
cord-256444-grw5s2pf	1504	64	antigen	antigen	NNP
cord-256444-grw5s2pf	1504	65	family	family	NN
cord-256444-grw5s2pf	1504	66	that	that	WDT
cord-256444-grw5s2pf	1504	67	serves	serve	VBZ
cord-256444-grw5s2pf	1504	68	as	as	IN
cord-256444-grw5s2pf	1504	69	a	a	DT
cord-256444-grw5s2pf	1504	70	receptor	receptor	NN
cord-256444-grw5s2pf	1504	71	for	for	IN
cord-256444-grw5s2pf	1504	72	mouse	mouse	NNP
cord-256444-grw5s2pf	1504	73	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1504	74	virus	virus	NN
cord-256444-grw5s2pf	1504	75	Fusion	fusion	NN
cord-256444-grw5s2pf	1504	76	-	-	HYPH
cord-256444-grw5s2pf	1504	77	defective	defective	JJ
cord-256444-grw5s2pf	1504	78	mutants	mutant	NNS
cord-256444-grw5s2pf	1504	79	of	of	IN
cord-256444-grw5s2pf	1504	80	mouse	mouse	NN
cord-256444-grw5s2pf	1504	81	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1504	82	virus	virus	NN
cord-256444-grw5s2pf	1504	83	A59	A59	NNP
cord-256444-grw5s2pf	1505	1	contain	contain	VB
cord-256444-grw5s2pf	1505	2	a	a	DT
cord-256444-grw5s2pf	1505	3	mutation	mutation	NN
cord-256444-grw5s2pf	1505	4	in	in	IN
cord-256444-grw5s2pf	1505	5	the	the	DT
cord-256444-grw5s2pf	1505	6	spike	spike	NN
cord-256444-grw5s2pf	1505	7	protein	protein	NN
cord-256444-grw5s2pf	1505	8	cleavage	cleavage	NN
cord-256444-grw5s2pf	1505	9	signal	signal	VBP
cord-256444-grw5s2pf	1505	10	An	an	DT
cord-256444-grw5s2pf	1505	11	NTPbinding	ntpbinding	NN
cord-256444-grw5s2pf	1505	12	motif	motif	NN
cord-256444-grw5s2pf	1505	13	is	be	VBZ
cord-256444-grw5s2pf	1505	14	the	the	DT
cord-256444-grw5s2pf	1505	15	most	most	RBS
cord-256444-grw5s2pf	1505	16	conserved	conserve	VBN
cord-256444-grw5s2pf	1505	17	sequence	sequence	NN
cord-256444-grw5s2pf	1505	18	in	in	IN
cord-256444-grw5s2pf	1505	19	a	a	DT
cord-256444-grw5s2pf	1505	20	highly	highly	RB
cord-256444-grw5s2pf	1505	21	diverged	diverged	JJ
cord-256444-grw5s2pf	1505	22	monophyletic	monophyletic	JJ
cord-256444-grw5s2pf	1505	23	group	group	NN
cord-256444-grw5s2pf	1505	24	of	of	IN
cord-256444-grw5s2pf	1505	25	proteins	protein	NNS
cord-256444-grw5s2pf	1505	26	involved	involve	VBN
cord-256444-grw5s2pf	1505	27	in	in	IN
cord-256444-grw5s2pf	1505	28	positive	positive	JJ
cord-256444-grw5s2pf	1505	29	strand	strand	NN
cord-256444-grw5s2pf	1505	30	RNAviral	rnaviral	JJ
cord-256444-grw5s2pf	1505	31	replication	replication	NN
cord-256444-grw5s2pf	1505	32	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1505	33	genome	genome	NN
cord-256444-grw5s2pf	1505	34	:	:	:
cord-256444-grw5s2pf	1506	1	Prediction	prediction	NN
cord-256444-grw5s2pf	1506	2	of	of	IN
cord-256444-grw5s2pf	1506	3	putative	putative	JJ
cord-256444-grw5s2pf	1506	4	functional	functional	JJ
cord-256444-grw5s2pf	1506	5	domains	domain	NNS
cord-256444-grw5s2pf	1506	6	in	in	IN
cord-256444-grw5s2pf	1506	7	the	the	DT
cord-256444-grw5s2pf	1506	8	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	1506	9	polyprotein	polyprotein	NN
cord-256444-grw5s2pf	1506	10	by	by	IN
cord-256444-grw5s2pf	1506	11	comparative	comparative	JJ
cord-256444-grw5s2pf	1506	12	amino	amino	NN
cord-256444-grw5s2pf	1506	13	acid	acid	NN
cord-256444-grw5s2pf	1506	14	sequence	sequence	NN
cord-256444-grw5s2pf	1506	15	analysis	analysis	NN
cord-256444-grw5s2pf	1506	16	Putative	Putative	NNP
cord-256444-grw5s2pf	1506	17	papain	papain	NN
cord-256444-grw5s2pf	1506	18	-	-	HYPH
cord-256444-grw5s2pf	1506	19	related	relate	VBN
cord-256444-grw5s2pf	1506	20	thiol	thiol	NN
cord-256444-grw5s2pf	1506	21	proteases	protease	NNS
cord-256444-grw5s2pf	1506	22	of	of	IN
cord-256444-grw5s2pf	1506	23	positive	positive	JJ
cord-256444-grw5s2pf	1506	24	-	-	HYPH
cord-256444-grw5s2pf	1506	25	strand	strand	NN
cord-256444-grw5s2pf	1506	26	RNA	RNA	NNP
cord-256444-grw5s2pf	1506	27	viruses	virus	NNS
cord-256444-grw5s2pf	1507	1	Single	single	JJ
cord-256444-grw5s2pf	1507	2	amino	amino	NN
cord-256444-grw5s2pf	1507	3	acid	acid	NN
cord-256444-grw5s2pf	1507	4	changes	change	NNS
cord-256444-grw5s2pf	1507	5	in	in	IN
cord-256444-grw5s2pf	1507	6	the	the	DT
cord-256444-grw5s2pf	1507	7	S2	S2	NNP
cord-256444-grw5s2pf	1507	8	subunit	subunit	NN
cord-256444-grw5s2pf	1507	9	of	of	IN
cord-256444-grw5s2pf	1507	10	the	the	DT
cord-256444-grw5s2pf	1507	11	MHV	MHV	NNP
cord-256444-grw5s2pf	1507	12	surface	surface	NN
cord-256444-grw5s2pf	1507	13	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1507	14	confer	confer	VBP
cord-256444-grw5s2pf	1507	15	resistance	resistance	NN
cord-256444-grw5s2pf	1507	16	to	to	IN
cord-256444-grw5s2pf	1507	17	neutralization	neutralization	NN
cord-256444-grw5s2pf	1507	18	by	by	IN
cord-256444-grw5s2pf	1507	19	S1	s1	NN
cord-256444-grw5s2pf	1507	20	subunit	subunit	NN
cord-256444-grw5s2pf	1507	21	-	-	HYPH
cord-256444-grw5s2pf	1507	22	specific	specific	JJ
cord-256444-grw5s2pf	1507	23	monoclonal	monoclonal	JJ
cord-256444-grw5s2pf	1507	24	antibody	antibody	NN
cord-256444-grw5s2pf	1507	25	Characterization	characterization	NN
cord-256444-grw5s2pf	1507	26	of	of	IN
cord-256444-grw5s2pf	1507	27	a	a	DT
cord-256444-grw5s2pf	1507	28	106-kDa	106-kda	CD
cord-256444-grw5s2pf	1507	29	polypeptide	polypeptide	NN
cord-256444-grw5s2pf	1507	30	encoded	encode	VBN
cord-256444-grw5s2pf	1507	31	in	in	IN
cord-256444-grw5s2pf	1507	32	gene	gene	NN
cord-256444-grw5s2pf	1507	33	1	1	CD
cord-256444-grw5s2pf	1507	34	of	of	IN
cord-256444-grw5s2pf	1507	35	the	the	DT
cord-256444-grw5s2pf	1507	36	human	human	JJ
cord-256444-grw5s2pf	1507	37	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1507	38	HCV	HCV	NNP
cord-256444-grw5s2pf	1507	39	2293	2293	CD
cord-256444-grw5s2pf	1507	40	Temperature	temperature	NN
cord-256444-grw5s2pf	1507	41	-	-	HYPH
cord-256444-grw5s2pf	1507	42	sensitive	sensitive	JJ
cord-256444-grw5s2pf	1507	43	mutants	mutant	NNS
cord-256444-grw5s2pf	1507	44	of	of	IN
cord-256444-grw5s2pf	1507	45	mouse	mouse	NN
cord-256444-grw5s2pf	1507	46	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1507	47	virus	virus	NN
cord-256444-grw5s2pf	1507	48	produce	produce	VBP
cord-256444-grw5s2pf	1507	49	a	a	DT
cord-256444-grw5s2pf	1507	50	high	high	JJ
cord-256444-grw5s2pf	1507	51	incidence	incidence	NN
cord-256444-grw5s2pf	1507	52	of	of	IN
cord-256444-grw5s2pf	1507	53	demyelination	demyelination	NN
cord-256444-grw5s2pf	1507	54	An	an	DT
cord-256444-grw5s2pf	1507	55	"	"	``
cord-256444-grw5s2pf	1507	56	elaborated	elaborate	VBN
cord-256444-grw5s2pf	1507	57	"	"	''
cord-256444-grw5s2pf	1507	58	pseudoknot	pseudoknot	NNP
cord-256444-grw5s2pf	1507	59	is	be	VBZ
cord-256444-grw5s2pf	1507	60	required	require	VBN
cord-256444-grw5s2pf	1507	61	for	for	IN
cord-256444-grw5s2pf	1507	62	high	high	JJ
cord-256444-grw5s2pf	1507	63	frequency	frequency	NN
cord-256444-grw5s2pf	1507	64	frameshifting	frameshifte	VBG
cord-256444-grw5s2pf	1507	65	during	during	IN
cord-256444-grw5s2pf	1507	66	translation	translation	NN
cord-256444-grw5s2pf	1507	67	of	of	IN
cord-256444-grw5s2pf	1507	68	HCV	HCV	NNP
cord-256444-grw5s2pf	1507	69	2293	2293	CD
cord-256444-grw5s2pf	1507	70	polymerase	polymerase	NN
cord-256444-grw5s2pf	1507	71	mRNA	mrna	NN
cord-256444-grw5s2pf	1507	72	Nucleotide	nucleotide	JJ
cord-256444-grw5s2pf	1507	73	sequence	sequence	NN
cord-256444-grw5s2pf	1507	74	of	of	IN
cord-256444-grw5s2pf	1507	75	the	the	DT
cord-256444-grw5s2pf	1507	76	human	human	JJ
cord-256444-grw5s2pf	1507	77	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1507	78	2293	2293	CD
cord-256444-grw5s2pf	1507	79	RNA	RNA	NNP
cord-256444-grw5s2pf	1507	80	polymerase	polymerase	NN
cord-256444-grw5s2pf	1507	81	locus	locus	NN
cord-256444-grw5s2pf	1507	82	Translational	translational	JJ
cord-256444-grw5s2pf	1507	83	control	control	NN
cord-256444-grw5s2pf	1507	84	in	in	IN
cord-256444-grw5s2pf	1507	85	murine	murine	JJ
cord-256444-grw5s2pf	1507	86	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1507	87	virus	virus	NN
cord-256444-grw5s2pf	1507	88	infection	infection	NN
cord-256444-grw5s2pf	1507	89	Quantification	quantification	NN
cord-256444-grw5s2pf	1507	90	of	of	IN
cord-256444-grw5s2pf	1507	91	individual	individual	JJ
cord-256444-grw5s2pf	1507	92	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1507	93	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1507	94	species	specie	NNS
cord-256444-grw5s2pf	1507	95	during	during	IN
cord-256444-grw5s2pf	1507	96	replication	replication	NN
cord-256444-grw5s2pf	1507	97	of	of	IN
cord-256444-grw5s2pf	1507	98	the	the	DT
cord-256444-grw5s2pf	1507	99	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1507	100	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1507	101	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1507	102	virus	virus	NN
cord-256444-grw5s2pf	1507	103	Investigation	investigation	NN
cord-256444-grw5s2pf	1507	104	of	of	IN
cord-256444-grw5s2pf	1507	105	the	the	DT
cord-256444-grw5s2pf	1507	106	control	control	NN
cord-256444-grw5s2pf	1507	107	of	of	IN
cord-256444-grw5s2pf	1507	108	coronavirus	coronavirus	NNP
cord-256444-grw5s2pf	1507	109	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1507	110	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1507	111	transcription	transcription	NN
cord-256444-grw5s2pf	1507	112	by	by	IN
cord-256444-grw5s2pf	1507	113	using	use	VBG
cord-256444-grw5s2pf	1507	114	T7-generated	t7-generate	VBN
cord-256444-grw5s2pf	1507	115	negative	negative	JJ
cord-256444-grw5s2pf	1507	116	-	-	HYPH
cord-256444-grw5s2pf	1507	117	sense	sense	NN
cord-256444-grw5s2pf	1508	1	RNA	RNA	NNP
cord-256444-grw5s2pf	1508	2	transcripts	transcript	NNS
cord-256444-grw5s2pf	1508	3	Anew	Anew	NNP
cord-256444-grw5s2pf	1508	4	superfamily	superfamily	NN
cord-256444-grw5s2pf	1508	5	ofreplicative	ofreplicative	JJ
cord-256444-grw5s2pf	1508	6	proteins	protein	NNS
cord-256444-grw5s2pf	1509	1	The	the	DT
cord-256444-grw5s2pf	1509	2	5'-end	5'-end	CD
cord-256444-grw5s2pf	1509	3	of	of	IN
cord-256444-grw5s2pf	1509	4	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1509	5	minus	minus	JJ
cord-256444-grw5s2pf	1509	6	-	-	HYPH
cord-256444-grw5s2pf	1509	7	strand	strand	NN
cord-256444-grw5s2pf	1509	8	RNAs	rna	NNS
cord-256444-grw5s2pf	1509	9	contains	contain	VBZ
cord-256444-grw5s2pf	1509	10	a	a	DT
cord-256444-grw5s2pf	1509	11	short	short	JJ
cord-256444-grw5s2pf	1509	12	poly(U	poly(u	$
cord-256444-grw5s2pf	1509	13	)	)	-RRB-
cord-256444-grw5s2pf	1509	14	tract	tract	NN
cord-256444-grw5s2pf	1509	15	Bovine	bovine	JJ
cord-256444-grw5s2pf	1509	16	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1509	17	mRNA	mrna	NN
cord-256444-grw5s2pf	1509	18	replication	replication	NN
cord-256444-grw5s2pf	1509	19	continues	continue	VBZ
cord-256444-grw5s2pf	1509	20	throughout	throughout	IN
cord-256444-grw5s2pf	1509	21	persistent	persistent	JJ
cord-256444-grw5s2pf	1509	22	infection	infection	NN
cord-256444-grw5s2pf	1509	23	in	in	IN
cord-256444-grw5s2pf	1509	24	cell	cell	NN
cord-256444-grw5s2pf	1509	25	culture	culture	NN
cord-256444-grw5s2pf	1510	1	Leader	Leader	NNP
cord-256444-grw5s2pf	1510	2	-	-	HYPH
cord-256444-grw5s2pf	1510	3	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1510	4	junction	junction	NN
cord-256444-grw5s2pf	1510	5	sequences	sequence	NNS
cord-256444-grw5s2pf	1510	6	are	be	VBP
cord-256444-grw5s2pf	1510	7	unique	unique	JJ
cord-256444-grw5s2pf	1510	8	for	for	IN
cord-256444-grw5s2pf	1510	9	each	each	DT
cord-256444-grw5s2pf	1510	10	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1510	11	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1510	12	species	specie	NNS
cord-256444-grw5s2pf	1510	13	in	in	IN
cord-256444-grw5s2pf	1510	14	the	the	DT
cord-256444-grw5s2pf	1510	15	bovine	bovine	JJ
cord-256444-grw5s2pf	1510	16	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1510	17	and	and	CC
cord-256444-grw5s2pf	1510	18	remain	remain	VB
cord-256444-grw5s2pf	1510	19	so	so	RB
cord-256444-grw5s2pf	1510	20	throughout	throughout	IN
cord-256444-grw5s2pf	1510	21	persistent	persistent	JJ
cord-256444-grw5s2pf	1510	22	infection	infection	NN
cord-256444-grw5s2pf	1511	1	A	a	DT
cord-256444-grw5s2pf	1511	2	translation	translation	NN
cord-256444-grw5s2pf	1511	3	-	-	HYPH
cord-256444-grw5s2pf	1511	4	attenuating	attenuate	VBG
cord-256444-grw5s2pf	1511	5	intraleader	intraleader	IN
cord-256444-grw5s2pf	1511	6	open	open	JJ
cord-256444-grw5s2pf	1511	7	reading	reading	NN
cord-256444-grw5s2pf	1511	8	frame	frame	NN
cord-256444-grw5s2pf	1511	9	is	be	VBZ
cord-256444-grw5s2pf	1511	10	selected	select	VBN
cord-256444-grw5s2pf	1511	11	on	on	IN
cord-256444-grw5s2pf	1511	12	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1511	13	mRNAs	mrna	NNS
cord-256444-grw5s2pf	1511	14	during	during	IN
cord-256444-grw5s2pf	1511	15	persistent	persistent	JJ
cord-256444-grw5s2pf	1511	16	infection	infection	NN
cord-256444-grw5s2pf	1511	17	Structural	structural	JJ
cord-256444-grw5s2pf	1511	18	proteins	protein	NNS
cord-256444-grw5s2pf	1511	19	of	of	IN
cord-256444-grw5s2pf	1511	20	human	human	JJ
cord-256444-grw5s2pf	1511	21	respiratory	respiratory	JJ
cord-256444-grw5s2pf	1511	22	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1511	23	OC43	OC43	NNP
cord-256444-grw5s2pf	1511	24	Synthesis	Synthesis	NNP
cord-256444-grw5s2pf	1511	25	and	and	CC
cord-256444-grw5s2pf	1511	26	processing	processing	NN
cord-256444-grw5s2pf	1511	27	of	of	IN
cord-256444-grw5s2pf	1511	28	the	the	DT
cord-256444-grw5s2pf	1511	29	bovine	bovine	JJ
cord-256444-grw5s2pf	1511	30	enteric	enteric	JJ
cord-256444-grw5s2pf	1511	31	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1511	32	hemagglutinin	hemagglutinin	NN
cord-256444-grw5s2pf	1511	33	protein	protein	NN
cord-256444-grw5s2pf	1511	34	Coronaviridae	Coronaviridae	NNP
cord-256444-grw5s2pf	1511	35	and	and	CC
cord-256444-grw5s2pf	1511	36	their	-PRON-	PRP$
cord-256444-grw5s2pf	1511	37	replication	replication	NN
cord-256444-grw5s2pf	1511	38	Tunicamycin	Tunicamycin	NNP
cord-256444-grw5s2pf	1511	39	-	-	HYPH
cord-256444-grw5s2pf	1511	40	resistant	resistant	JJ
cord-256444-grw5s2pf	1511	41	glycosylation	glycosylation	NN
cord-256444-grw5s2pf	1511	42	of	of	IN
cord-256444-grw5s2pf	1511	43	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1511	44	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1511	45	:	:	:
cord-256444-grw5s2pf	1511	46	Demonstration	demonstration	NN
cord-256444-grw5s2pf	1511	47	of	of	IN
cord-256444-grw5s2pf	1511	48	a	a	DT
cord-256444-grw5s2pf	1511	49	novel	novel	JJ
cord-256444-grw5s2pf	1511	50	type	type	NN
cord-256444-grw5s2pf	1511	51	of	of	IN
cord-256444-grw5s2pf	1511	52	viral	viral	JJ
cord-256444-grw5s2pf	1511	53	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1511	54	Analysis	Analysis	NNP
cord-256444-grw5s2pf	1511	55	of	of	IN
cord-256444-grw5s2pf	1511	56	a	a	DT
cord-256444-grw5s2pf	1511	57	9.6	9.6	CD
cord-256444-grw5s2pf	1511	58	kb	kb	NNP
cord-256444-grw5s2pf	1511	59	sequence	sequence	NN
cord-256444-grw5s2pf	1511	60	from	from	IN
cord-256444-grw5s2pf	1511	61	the	the	DT
cord-256444-grw5s2pf	1511	62	3	3	CD
cord-256444-grw5s2pf	1511	63	'	'	NN
cord-256444-grw5s2pf	1511	64	end	end	NN
cord-256444-grw5s2pf	1511	65	of	of	IN
cord-256444-grw5s2pf	1511	66	canine	canine	JJ
cord-256444-grw5s2pf	1511	67	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1511	68	genomic	genomic	JJ
cord-256444-grw5s2pf	1511	69	RNA	RNA	NNP
cord-256444-grw5s2pf	1511	70	Identification	Identification	NNP
cord-256444-grw5s2pf	1511	71	ofthe	ofthe	DT
cord-256444-grw5s2pf	1511	72	murine	murine	JJ
cord-256444-grw5s2pf	1511	73	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1511	74	p28	p28	CD
cord-256444-grw5s2pf	1511	75	cleavage	cleavage	NN
cord-256444-grw5s2pf	1511	76	site	site	NN
cord-256444-grw5s2pf	1512	1	The	the	DT
cord-256444-grw5s2pf	1512	2	S1	s1	NN
cord-256444-grw5s2pf	1512	3	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1512	4	but	but	CC
cord-256444-grw5s2pf	1512	5	not	not	RB
cord-256444-grw5s2pf	1512	6	the	the	DT
cord-256444-grw5s2pf	1512	7	N	N	NNP
cord-256444-grw5s2pf	1512	8	or	or	CC
cord-256444-grw5s2pf	1512	9	M	M	NNP
cord-256444-grw5s2pf	1512	10	proteins	protein	NNS
cord-256444-grw5s2pf	1512	11	of	of	IN
cord-256444-grw5s2pf	1512	12	avian	avian	JJ
cord-256444-grw5s2pf	1512	13	infectious	infectious	JJ
cord-256444-grw5s2pf	1512	14	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1512	15	virus	virus	NN
cord-256444-grw5s2pf	1512	16	induces	induce	VBZ
cord-256444-grw5s2pf	1512	17	protection	protection	NN
cord-256444-grw5s2pf	1512	18	in	in	IN
cord-256444-grw5s2pf	1512	19	vaccinated	vaccinated	JJ
cord-256444-grw5s2pf	1512	20	chickens	chicken	NNS
cord-256444-grw5s2pf	1512	21	Synthesis	Synthesis	NNP
cord-256444-grw5s2pf	1512	22	of	of	IN
cord-256444-grw5s2pf	1512	23	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1512	24	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1512	25	's	's	POS
cord-256444-grw5s2pf	1512	26	of	of	IN
cord-256444-grw5s2pf	1512	27	mouse	mouse	NNP
cord-256444-grw5s2pf	1512	28	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1512	29	virus	virus	NN
cord-256444-grw5s2pf	1512	30	is	be	VBZ
cord-256444-grw5s2pf	1512	31	initiated	initiate	VBN
cord-256444-grw5s2pf	1512	32	independently	independently	RB
cord-256444-grw5s2pf	1512	33	:	:	:
cord-256444-grw5s2pf	1512	34	Evidence	evidence	NN
cord-256444-grw5s2pf	1512	35	from	from	IN
cord-256444-grw5s2pf	1512	36	UV	uv	NN
cord-256444-grw5s2pf	1512	37	transcription	transcription	NN
cord-256444-grw5s2pf	1512	38	mapping	mapping	NN
cord-256444-grw5s2pf	1512	39	Mechanism	mechanism	NN
cord-256444-grw5s2pf	1512	40	of	of	IN
cord-256444-grw5s2pf	1512	41	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1512	42	transcription	transcription	NN
cord-256444-grw5s2pf	1512	43	:	:	:
cord-256444-grw5s2pf	1512	44	Duration	duration	NN
cord-256444-grw5s2pf	1512	45	of	of	IN
cord-256444-grw5s2pf	1512	46	primary	primary	JJ
cord-256444-grw5s2pf	1512	47	transcription	transcription	NN
cord-256444-grw5s2pf	1512	48	initiation	initiation	NN
cord-256444-grw5s2pf	1512	49	activity	activity	NN
cord-256444-grw5s2pf	1512	50	and	and	CC
cord-256444-grw5s2pf	1512	51	effects	effect	NNS
cord-256444-grw5s2pf	1512	52	of	of	IN
cord-256444-grw5s2pf	1512	53	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1512	54	RNA	RNA	NNP
cord-256444-grw5s2pf	1512	55	transcription	transcription	NN
cord-256444-grw5s2pf	1512	56	on	on	IN
cord-256444-grw5s2pf	1512	57	RNA	RNA	NNP
cord-256444-grw5s2pf	1512	58	replication	replication	NN
cord-256444-grw5s2pf	1512	59	Evidence	evidence	NN
cord-256444-grw5s2pf	1512	60	for	for	IN
cord-256444-grw5s2pf	1512	61	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1512	62	discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	1512	63	transcription	transcription	NN
cord-256444-grw5s2pf	1512	64	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1512	65	transcription	transcription	NN
cord-256444-grw5s2pf	1512	66	mediated	mediate	VBN
cord-256444-grw5s2pf	1512	67	by	by	IN
cord-256444-grw5s2pf	1512	68	sequences	sequence	NNS
cord-256444-grw5s2pf	1512	69	flanking	flank	VBG
cord-256444-grw5s2pf	1512	70	the	the	DT
cord-256444-grw5s2pf	1512	71	transcription	transcription	NN
cord-256444-grw5s2pf	1512	72	consensus	consensus	NN
cord-256444-grw5s2pf	1512	73	sequence	sequence	NN
cord-256444-grw5s2pf	1512	74	A	a	DT
cord-256444-grw5s2pf	1512	75	novel	novel	JJ
cord-256444-grw5s2pf	1512	76	variant	variant	NN
cord-256444-grw5s2pf	1512	77	of	of	IN
cord-256444-grw5s2pf	1512	78	avian	avian	JJ
cord-256444-grw5s2pf	1512	79	infectious	infectious	JJ
cord-256444-grw5s2pf	1512	80	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1512	81	virus	virus	NN
cord-256444-grw5s2pf	1512	82	resulting	result	VBG
cord-256444-grw5s2pf	1512	83	from	from	IN
cord-256444-grw5s2pf	1512	84	recombination	recombination	NN
cord-256444-grw5s2pf	1512	85	among	among	IN
cord-256444-grw5s2pf	1512	86	three	three	CD
cord-256444-grw5s2pf	1512	87	different	different	JJ
cord-256444-grw5s2pf	1512	88	strains	strain	NNS
cord-256444-grw5s2pf	1512	89	Mutagenic	mutagenic	JJ
cord-256444-grw5s2pf	1512	90	analysis	analysis	NN
cord-256444-grw5s2pf	1512	91	of	of	IN
cord-256444-grw5s2pf	1512	92	the	the	DT
cord-256444-grw5s2pf	1512	93	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1512	94	intergenic	intergenic	JJ
cord-256444-grw5s2pf	1512	95	consensus	consensus	NN
cord-256444-grw5s2pf	1512	96	sequence	sequence	NN
cord-256444-grw5s2pf	1513	1	The	the	DT
cord-256444-grw5s2pf	1513	2	effect	effect	NN
cord-256444-grw5s2pf	1513	3	of	of	IN
cord-256444-grw5s2pf	1513	4	two	two	CD
cord-256444-grw5s2pf	1513	5	closely	closely	RB
cord-256444-grw5s2pf	1513	6	inserted	insert	VBN
cord-256444-grw5s2pf	1513	7	transcription	transcription	NN
cord-256444-grw5s2pf	1513	8	consensus	consensus	NN
cord-256444-grw5s2pf	1513	9	sequences	sequence	NNS
cord-256444-grw5s2pf	1513	10	on	on	IN
cord-256444-grw5s2pf	1513	11	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1513	12	transcription	transcription	NN
cord-256444-grw5s2pf	1514	1	The	the	DT
cord-256444-grw5s2pf	1514	2	amino	amino	NN
cord-256444-grw5s2pf	1514	3	-	-	HYPH
cord-256444-grw5s2pf	1514	4	terminal	terminal	NN
cord-256444-grw5s2pf	1514	5	signal	signal	NN
cord-256444-grw5s2pf	1514	6	peptide	peptide	NN
cord-256444-grw5s2pf	1514	7	on	on	IN
cord-256444-grw5s2pf	1514	8	the	the	DT
cord-256444-grw5s2pf	1514	9	porcine	porcine	JJ
cord-256444-grw5s2pf	1514	10	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1514	11	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1514	12	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1514	13	matrix	matrix	NN
cord-256444-grw5s2pf	1514	14	protein	protein	NN
cord-256444-grw5s2pf	1514	15	is	be	VBZ
cord-256444-grw5s2pf	1514	16	not	not	RB
cord-256444-grw5s2pf	1514	17	an	an	DT
cord-256444-grw5s2pf	1514	18	absolute	absolute	JJ
cord-256444-grw5s2pf	1514	19	requirement	requirement	NN
cord-256444-grw5s2pf	1514	20	for	for	IN
cord-256444-grw5s2pf	1514	21	membrane	membrane	NN
cord-256444-grw5s2pf	1514	22	translocation	translocation	NN
cord-256444-grw5s2pf	1514	23	and	and	CC
cord-256444-grw5s2pf	1514	24	glycosylation	glycosylation	NN
cord-256444-grw5s2pf	1514	25	Multiple	multiple	JJ
cord-256444-grw5s2pf	1514	26	recombination	recombination	NN
cord-256444-grw5s2pf	1514	27	sites	site	NNS
cord-256444-grw5s2pf	1514	28	at	at	IN
cord-256444-grw5s2pf	1514	29	the	the	DT
cord-256444-grw5s2pf	1514	30	5'-end	5'-end	CD
cord-256444-grw5s2pf	1514	31	of	of	IN
cord-256444-grw5s2pf	1514	32	murine	murine	JJ
cord-256444-grw5s2pf	1514	33	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1514	34	RNA	RNA	NNP
cord-256444-grw5s2pf	1514	35	Temporal	temporal	JJ
cord-256444-grw5s2pf	1514	36	regulation	regulation	NN
cord-256444-grw5s2pf	1514	37	of	of	IN
cord-256444-grw5s2pf	1514	38	bovine	bovine	JJ
cord-256444-grw5s2pf	1514	39	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1514	40	RNA	rna	NN
cord-256444-grw5s2pf	1514	41	synthesis	synthesis	NN
cord-256444-grw5s2pf	1514	42	In	in	IN
cord-256444-grw5s2pf	1514	43	vivo	vivo	NNP
cord-256444-grw5s2pf	1514	44	RNA	RNA	NNP
cord-256444-grw5s2pf	1514	45	-	-	HYPH
cord-256444-grw5s2pf	1514	46	RNA	RNA	NNP
cord-256444-grw5s2pf	1514	47	recombination	recombination	NN
cord-256444-grw5s2pf	1514	48	of	of	IN
cord-256444-grw5s2pf	1514	49	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1514	50	in	in	IN
cord-256444-grw5s2pf	1514	51	mouse	mouse	NN
cord-256444-grw5s2pf	1514	52	brain	brain	NN
cord-256444-grw5s2pf	1514	53	RNA	RNA	NNP
cord-256444-grw5s2pf	1514	54	recombination	recombination	NN
cord-256444-grw5s2pf	1514	55	of	of	IN
cord-256444-grw5s2pf	1514	56	murine	murine	JJ
cord-256444-grw5s2pf	1514	57	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1514	58	:	:	:
cord-256444-grw5s2pf	1514	59	Recombination	recombination	NN
cord-256444-grw5s2pf	1514	60	between	between	IN
cord-256444-grw5s2pf	1514	61	fusion	fusion	NN
cord-256444-grw5s2pf	1514	62	-	-	HYPH
cord-256444-grw5s2pf	1514	63	positive	positive	JJ
cord-256444-grw5s2pf	1514	64	MHV	MHV	NNP
cord-256444-grw5s2pf	1514	65	-	-	HYPH
cord-256444-grw5s2pf	1514	66	A59	A59	NNP
cord-256444-grw5s2pf	1514	67	and	and	CC
cord-256444-grw5s2pf	1514	68	fusion	fusion	NN
cord-256444-grw5s2pf	1514	69	-	-	HYPH
cord-256444-grw5s2pf	1514	70	negative	negative	JJ
cord-256444-grw5s2pf	1515	1	MHV-2	MHV-2	NNP
cord-256444-grw5s2pf	1515	2	Inhibition	inhibition	NN
cord-256444-grw5s2pf	1515	3	of	of	IN
cord-256444-grw5s2pf	1515	4	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1515	5	2293	2293	CD
cord-256444-grw5s2pf	1515	6	replication	replication	NN
cord-256444-grw5s2pf	1515	7	by	by	IN
cord-256444-grw5s2pf	1515	8	actinomycin	actinomycin	NNS
cord-256444-grw5s2pf	1515	9	D	D	NNP
cord-256444-grw5s2pf	1515	10	Structure	Structure	NNP
cord-256444-grw5s2pf	1515	11	and	and	CC
cord-256444-grw5s2pf	1515	12	orientation	orientation	NN
cord-256444-grw5s2pf	1515	13	of	of	IN
cord-256444-grw5s2pf	1515	14	expressed	express	VBN
cord-256444-grw5s2pf	1515	15	bovine	bovine	JJ
cord-256444-grw5s2pf	1515	16	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1515	17	hemagglutinin	hemagglutinin	NN
cord-256444-grw5s2pf	1515	18	-	-	HYPH
cord-256444-grw5s2pf	1515	19	esterase	esterase	NN
cord-256444-grw5s2pf	1515	20	protein	protein	NN
cord-256444-grw5s2pf	1515	21	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1515	22	protein	protein	NN
cord-256444-grw5s2pf	1515	23	processing	processing	NN
cord-256444-grw5s2pf	1515	24	and	and	CC
cord-256444-grw5s2pf	1515	25	RNA	RNA	NNP
cord-256444-grw5s2pf	1515	26	synthesis	synthesis	NN
cord-256444-grw5s2pf	1515	27	is	be	VBZ
cord-256444-grw5s2pf	1515	28	inhibited	inhibit	VBN
cord-256444-grw5s2pf	1515	29	by	by	IN
cord-256444-grw5s2pf	1515	30	the	the	DT
cord-256444-grw5s2pf	1515	31	cysteine	cysteine	NN
cord-256444-grw5s2pf	1515	32	proteinase	proteinase	NN
cord-256444-grw5s2pf	1515	33	inhibitor	inhibitor	NN
cord-256444-grw5s2pf	1515	34	E64d	e64d	NN
cord-256444-grw5s2pf	1515	35	Two	two	CD
cord-256444-grw5s2pf	1515	36	murine	murine	JJ
cord-256444-grw5s2pf	1515	37	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1515	38	genes	gene	NNS
cord-256444-grw5s2pf	1515	39	suffice	suffice	VBP
cord-256444-grw5s2pf	1515	40	for	for	IN
cord-256444-grw5s2pf	1515	41	viral	viral	JJ
cord-256444-grw5s2pf	1515	42	RNA	RNA	NNP
cord-256444-grw5s2pf	1515	43	synthesis	synthesis	NN
cord-256444-grw5s2pf	1515	44	Characterization	characterization	NN
cord-256444-grw5s2pf	1515	45	of	of	IN
cord-256444-grw5s2pf	1515	46	a	a	DT
cord-256444-grw5s2pf	1515	47	murine	murine	JJ
cord-256444-grw5s2pf	1515	48	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1515	49	defective	defective	JJ
cord-256444-grw5s2pf	1515	50	interfering	interfere	VBG
cord-256444-grw5s2pf	1515	51	RNA	RNA	NNP
cord-256444-grw5s2pf	1515	52	internal	internal	JJ
cord-256444-grw5s2pf	1515	53	cis	cis	NN
cord-256444-grw5s2pf	1515	54	-	-	HYPH
cord-256444-grw5s2pf	1515	55	acting	act	VBG
cord-256444-grw5s2pf	1515	56	replication	replication	NN
cord-256444-grw5s2pf	1515	57	signal	signal	NN
cord-256444-grw5s2pf	1515	58	Generation	generation	NN
cord-256444-grw5s2pf	1515	59	and	and	CC
cord-256444-grw5s2pf	1515	60	selection	selection	NN
cord-256444-grw5s2pf	1515	61	of	of	IN
cord-256444-grw5s2pf	1515	62	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1515	63	defective	defective	JJ
cord-256444-grw5s2pf	1515	64	interfering	interfere	VBG
cord-256444-grw5s2pf	1515	65	RNA	RNA	NNP
cord-256444-grw5s2pf	1515	66	with	with	IN
cord-256444-grw5s2pf	1515	67	large	large	JJ
cord-256444-grw5s2pf	1515	68	open	open	JJ
cord-256444-grw5s2pf	1515	69	reading	reading	NN
cord-256444-grw5s2pf	1515	70	frame	frame	NN
cord-256444-grw5s2pf	1515	71	by	by	IN
cord-256444-grw5s2pf	1515	72	RNA	RNA	NNP
cord-256444-grw5s2pf	1515	73	recombination	recombination	NN
cord-256444-grw5s2pf	1515	74	and	and	CC
cord-256444-grw5s2pf	1515	75	possible	possible	JJ
cord-256444-grw5s2pf	1515	76	editing	editing	NN
cord-256444-grw5s2pf	1515	77	Analysis	Analysis	NNP
cord-256444-grw5s2pf	1515	78	of	of	IN
cord-256444-grw5s2pf	1515	79	cis	cis	NNP
cord-256444-grw5s2pf	1515	80	-	-	HYPH
cord-256444-grw5s2pf	1515	81	actingsequences	actingsequence	NNS
cord-256444-grw5s2pf	1515	82	essential	essential	JJ
cord-256444-grw5s2pf	1515	83	for	for	IN
cord-256444-grw5s2pf	1515	84	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1515	85	defective	defective	JJ
cord-256444-grw5s2pf	1515	86	interfering	interfere	VBG
cord-256444-grw5s2pf	1515	87	RNA	RNA	NNP
cord-256444-grw5s2pf	1515	88	replication	replication	NN
cord-256444-grw5s2pf	1515	89	Bovine	bovine	JJ
cord-256444-grw5s2pf	1515	90	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1515	91	hemagglutinin	hemagglutinin	NN
cord-256444-grw5s2pf	1515	92	protein	protein	NN
cord-256444-grw5s2pf	1515	93	Infectious	Infectious	NNP
cord-256444-grw5s2pf	1515	94	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1515	95	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1515	96	M	M	NNP
cord-256444-grw5s2pf	1515	97	proteins	protein	NNS
cord-256444-grw5s2pf	1515	98	accumulate	accumulate	VBP
cord-256444-grw5s2pf	1515	99	in	in	IN
cord-256444-grw5s2pf	1515	100	the	the	DT
cord-256444-grw5s2pf	1515	101	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1515	102	complex	complex	NN
cord-256444-grw5s2pf	1515	103	beyond	beyond	IN
cord-256444-grw5s2pf	1515	104	the	the	DT
cord-256444-grw5s2pf	1515	105	site	site	NN
cord-256444-grw5s2pf	1515	106	of	of	IN
cord-256444-grw5s2pf	1515	107	virion	virion	NN
cord-256444-grw5s2pf	1515	108	budding	bud	VBG
cord-256444-grw5s2pf	1515	109	Host	host	JJ
cord-256444-grw5s2pf	1515	110	genetic	genetic	JJ
cord-256444-grw5s2pf	1515	111	control	control	NN
cord-256444-grw5s2pf	1515	112	of	of	IN
cord-256444-grw5s2pf	1515	113	mouse	mouse	NNP
cord-256444-grw5s2pf	1515	114	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1515	115	virus	virus	NN
cord-256444-grw5s2pf	1516	1	type-4	type-4	NNP
cord-256444-grw5s2pf	1517	1	(	(	-LRB-
cord-256444-grw5s2pf	1517	2	JHM	JHM	NNP
cord-256444-grw5s2pf	1517	3	strain	strain	VB
cord-256444-grw5s2pf	1517	4	)	)	-RRB-
cord-256444-grw5s2pf	1517	5	replication	replication	NN
cord-256444-grw5s2pf	1517	6	.	.	.
cord-256444-grw5s2pf	1518	1	11	11	CD
cord-256444-grw5s2pf	1518	2	.	.	.
cord-256444-grw5s2pf	1519	1	The	the	DT
cord-256444-grw5s2pf	1519	2	gene	gene	NN
cord-256444-grw5s2pf	1519	3	locus	locus	NN
cord-256444-grw5s2pf	1519	4	for	for	IN
cord-256444-grw5s2pf	1519	5	susceptibility	susceptibility	NN
cord-256444-grw5s2pf	1519	6	is	be	VBZ
cord-256444-grw5s2pf	1519	7	linked	link	VBN
cord-256444-grw5s2pf	1519	8	to	to	IN
cord-256444-grw5s2pf	1519	9	the	the	DT
cord-256444-grw5s2pf	1519	10	Svp-2	Svp-2	NNP
cord-256444-grw5s2pf	1519	11	locus	locus	NN
cord-256444-grw5s2pf	1519	12	on	on	IN
cord-256444-grw5s2pf	1519	13	mouse	mouse	NN
cord-256444-grw5s2pf	1519	14	chromosome	chromosome	NN
cord-256444-grw5s2pf	1519	15	7	7	CD
cord-256444-grw5s2pf	1519	16	Repair	repair	NN
cord-256444-grw5s2pf	1519	17	and	and	CC
cord-256444-grw5s2pf	1519	18	mutagenesis	mutagenesis	NN
cord-256444-grw5s2pf	1519	19	of	of	IN
cord-256444-grw5s2pf	1519	20	the	the	DT
cord-256444-grw5s2pf	1519	21	genome	genome	NN
cord-256444-grw5s2pf	1519	22	of	of	IN
cord-256444-grw5s2pf	1519	23	a	a	DT
cord-256444-grw5s2pf	1519	24	deletion	deletion	NN
cord-256444-grw5s2pf	1519	25	mutant	mutant	NN
cord-256444-grw5s2pf	1519	26	of	of	IN
cord-256444-grw5s2pf	1519	27	the	the	DT
cord-256444-grw5s2pf	1519	28	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1519	29	mouse	mouse	NN
cord-256444-grw5s2pf	1519	30	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1519	31	virus	virus	NN
cord-256444-grw5s2pf	1519	32	by	by	IN
cord-256444-grw5s2pf	1519	33	targeted	target	VBN
cord-256444-grw5s2pf	1519	34	RNA	RNA	NNP
cord-256444-grw5s2pf	1519	35	recombination	recombination	NN
cord-256444-grw5s2pf	1519	36	Differential	Differential	NNP
cord-256444-grw5s2pf	1519	37	premature	premature	JJ
cord-256444-grw5s2pf	1519	38	termination	termination	NN
cord-256444-grw5s2pf	1519	39	of	of	IN
cord-256444-grw5s2pf	1519	40	transcription	transcription	NN
cord-256444-grw5s2pf	1519	41	as	as	IN
cord-256444-grw5s2pf	1519	42	a	a	DT
cord-256444-grw5s2pf	1519	43	proposed	propose	VBN
cord-256444-grw5s2pf	1519	44	mechanism	mechanism	NN
cord-256444-grw5s2pf	1519	45	for	for	IN
cord-256444-grw5s2pf	1519	46	the	the	DT
cord-256444-grw5s2pf	1519	47	regulation	regulation	NN
cord-256444-grw5s2pf	1519	48	of	of	IN
cord-256444-grw5s2pf	1519	49	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1519	50	gene	gene	NN
cord-256444-grw5s2pf	1519	51	expression	expression	NN
cord-256444-grw5s2pf	1520	1	Early	early	JJ
cord-256444-grw5s2pf	1520	2	events	event	NNS
cord-256444-grw5s2pf	1520	3	of	of	IN
cord-256444-grw5s2pf	1520	4	importance	importance	NN
cord-256444-grw5s2pf	1520	5	in	in	IN
cord-256444-grw5s2pf	1520	6	determining	determine	VBG
cord-256444-grw5s2pf	1520	7	host	host	NN
cord-256444-grw5s2pf	1520	8	cell	cell	NN
cord-256444-grw5s2pf	1520	9	permissiveness	permissiveness	NN
cord-256444-grw5s2pf	1520	10	to	to	TO
cord-256444-grw5s2pf	1520	11	mouse	mouse	VB
cord-256444-grw5s2pf	1520	12	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1520	13	virus	virus	NN
cord-256444-grw5s2pf	1520	14	infection	infection	NN
cord-256444-grw5s2pf	1520	15	Differentiation	differentiation	NN
cord-256444-grw5s2pf	1520	16	of	of	IN
cord-256444-grw5s2pf	1520	17	acid	acid	NN
cord-256444-grw5s2pf	1520	18	-	-	HYPH
cord-256444-grw5s2pf	1520	19	pH	ph	NN
cord-256444-grw5s2pf	1520	20	-	-	HYPH
cord-256444-grw5s2pf	1520	21	dependent	dependent	JJ
cord-256444-grw5s2pf	1520	22	and	and	CC
cord-256444-grw5s2pf	1520	23	-nondependent	-nondependent	JJ
cord-256444-grw5s2pf	1520	24	entry	entry	NN
cord-256444-grw5s2pf	1520	25	pathways	pathway	NNS
cord-256444-grw5s2pf	1520	26	for	for	IN
cord-256444-grw5s2pf	1520	27	mouse	mouse	NN
cord-256444-grw5s2pf	1520	28	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1520	29	virus	virus	NN
cord-256444-grw5s2pf	1520	30	Temperature	temperature	NN
cord-256444-grw5s2pf	1520	31	-	-	HYPH
cord-256444-grw5s2pf	1520	32	sensitive	sensitive	JJ
cord-256444-grw5s2pf	1520	33	mutants	mutant	NNS
cord-256444-grw5s2pf	1520	34	of	of	IN
cord-256444-grw5s2pf	1520	35	mouse	mouse	NN
cord-256444-grw5s2pf	1520	36	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1520	37	virus	virus	NN
cord-256444-grw5s2pf	1520	38	strain	strain	VBP
cord-256444-grw5s2pf	1520	39	A59	A59	NNP
cord-256444-grw5s2pf	1520	40	:	:	:
cord-256444-grw5s2pf	1520	41	Isolation	isolation	NN
cord-256444-grw5s2pf	1520	42	,	,	,
cord-256444-grw5s2pf	1520	43	characterization	characterization	NN
cord-256444-grw5s2pf	1520	44	and	and	CC
cord-256444-grw5s2pf	1520	45	neuropathogenic	neuropathogenic	NNP
cord-256444-grw5s2pf	1520	46	properties	property	NNS
cord-256444-grw5s2pf	1520	47	Toroviruses	Toroviruses	NNPS
cord-256444-grw5s2pf	1520	48	of	of	IN
cord-256444-grw5s2pf	1520	49	animals	animal	NNS
cord-256444-grw5s2pf	1520	50	and	and	CC
cord-256444-grw5s2pf	1520	51	humans	human	NNS
cord-256444-grw5s2pf	1520	52	:	:	:
cord-256444-grw5s2pf	1521	1	A	a	DT
cord-256444-grw5s2pf	1521	2	review	review	NN
cord-256444-grw5s2pf	1521	3	Experimental	experimental	JJ
cord-256444-grw5s2pf	1521	4	evidence	evidence	NN
cord-256444-grw5s2pf	1521	5	of	of	IN
cord-256444-grw5s2pf	1521	6	recombination	recombination	NN
cord-256444-grw5s2pf	1521	7	in	in	IN
cord-256444-grw5s2pf	1521	8	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1521	9	infectious	infectious	JJ
cord-256444-grw5s2pf	1521	10	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1521	11	virus	virus	NN
cord-256444-grw5s2pf	1521	12	Characterization	characterization	NN
cord-256444-grw5s2pf	1521	13	of	of	IN
cord-256444-grw5s2pf	1521	14	the	the	DT
cord-256444-grw5s2pf	1521	15	budding	bud	VBG
cord-256444-grw5s2pf	1521	16	compartment	compartment	NN
cord-256444-grw5s2pf	1521	17	of	of	IN
cord-256444-grw5s2pf	1521	18	mouse	mouse	NNP
cord-256444-grw5s2pf	1521	19	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1521	20	virus	virus	NN
cord-256444-grw5s2pf	1521	21	:	:	:
cord-256444-grw5s2pf	1522	1	Evidence	evidence	NN
cord-256444-grw5s2pf	1522	2	that	that	DT
cord-256444-grw5s2pf	1522	3	transport	transport	NN
cord-256444-grw5s2pf	1522	4	from	from	IN
cord-256444-grw5s2pf	1522	5	the	the	DT
cord-256444-grw5s2pf	1522	6	RER	RER	NNP
cord-256444-grw5s2pf	1522	7	to	to	IN
cord-256444-grw5s2pf	1522	8	the	the	DT
cord-256444-grw5s2pf	1522	9	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1522	10	complex	complex	NN
cord-256444-grw5s2pf	1522	11	requires	require	VBZ
cord-256444-grw5s2pf	1522	12	only	only	RB
cord-256444-grw5s2pf	1522	13	one	one	CD
cord-256444-grw5s2pf	1522	14	vesicular	vesicular	JJ
cord-256444-grw5s2pf	1522	15	transport	transport	NN
cord-256444-grw5s2pf	1522	16	step	step	NN
cord-256444-grw5s2pf	1522	17	Tandem	tandem	JJ
cord-256444-grw5s2pf	1522	18	placement	placement	NN
cord-256444-grw5s2pf	1522	19	of	of	IN
cord-256444-grw5s2pf	1522	20	a	a	DT
cord-256444-grw5s2pf	1522	21	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1522	22	promoter	promoter	NN
cord-256444-grw5s2pf	1522	23	results	result	NNS
cord-256444-grw5s2pf	1522	24	in	in	IN
cord-256444-grw5s2pf	1522	25	enhanced	enhance	VBN
cord-256444-grw5s2pf	1522	26	mRNA	mrna	NN
cord-256444-grw5s2pf	1522	27	synthesis	synthesis	NN
cord-256444-grw5s2pf	1522	28	from	from	IN
cord-256444-grw5s2pf	1522	29	the	the	DT
cord-256444-grw5s2pf	1522	30	downstream	downstream	NN
cord-256444-grw5s2pf	1522	31	-	-	HYPH
cord-256444-grw5s2pf	1522	32	most	most	JJS
cord-256444-grw5s2pf	1522	33	initiation	initiation	NN
cord-256444-grw5s2pf	1522	34	site	site	NN
cord-256444-grw5s2pf	1522	35	Early	early	JJ
cord-256444-grw5s2pf	1522	36	interaction	interaction	NN
cord-256444-grw5s2pf	1522	37	between	between	IN
cord-256444-grw5s2pf	1522	38	mouse	mouse	NN
cord-256444-grw5s2pf	1522	39	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1522	40	virus	virus	NN
cord-256444-grw5s2pf	1522	41	3	3	CD
cord-256444-grw5s2pf	1522	42	and	and	CC
cord-256444-grw5s2pf	1522	43	cells	cell	NNS
cord-256444-grw5s2pf	1522	44	Entry	Entry	NNP
cord-256444-grw5s2pf	1522	45	of	of	IN
cord-256444-grw5s2pf	1522	46	mouse	mouse	NN
cord-256444-grw5s2pf	1522	47	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1522	48	virus	virus	NN
cord-256444-grw5s2pf	1522	49	3	3	CD
cord-256444-grw5s2pf	1522	50	into	into	IN
cord-256444-grw5s2pf	1522	51	cells	cell	NNS
cord-256444-grw5s2pf	1522	52	Localization	localization	NN
cord-256444-grw5s2pf	1522	53	of	of	IN
cord-256444-grw5s2pf	1522	54	neutralizing	neutralize	VBG
cord-256444-grw5s2pf	1522	55	epitopes	epitope	NNS
cord-256444-grw5s2pf	1522	56	and	and	CC
cord-256444-grw5s2pf	1522	57	the	the	DT
cord-256444-grw5s2pf	1522	58	receptor	receptor	NN
cord-256444-grw5s2pf	1522	59	-	-	HYPH
cord-256444-grw5s2pf	1522	60	binding	bind	VBG
cord-256444-grw5s2pf	1522	61	site	site	NN
cord-256444-grw5s2pf	1522	62	within	within	IN
cord-256444-grw5s2pf	1522	63	the	the	DT
cord-256444-grw5s2pf	1522	64	amino	amino	NN
cord-256444-grw5s2pf	1522	65	-	-	HYPH
cord-256444-grw5s2pf	1522	66	terminal	terminal	NN
cord-256444-grw5s2pf	1522	67	330	330	CD
cord-256444-grw5s2pf	1522	68	amino	amino	NN
cord-256444-grw5s2pf	1522	69	acids	acid	NNS
cord-256444-grw5s2pf	1522	70	of	of	IN
cord-256444-grw5s2pf	1522	71	the	the	DT
cord-256444-grw5s2pf	1522	72	murine	murine	JJ
cord-256444-grw5s2pf	1522	73	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1522	74	spike	spike	NN
cord-256444-grw5s2pf	1522	75	protein	protein	NN
cord-256444-grw5s2pf	1522	76	Structural	Structural	NNP
cord-256444-grw5s2pf	1522	77	and	and	CC
cord-256444-grw5s2pf	1522	78	fimctional	fimctional	JJ
cord-256444-grw5s2pf	1522	79	analysis	analysis	NN
cord-256444-grw5s2pf	1522	80	of	of	IN
cord-256444-grw5s2pf	1522	81	the	the	DT
cord-256444-grw5s2pf	1522	82	surface	surface	NN
cord-256444-grw5s2pf	1522	83	protein	protein	NN
cord-256444-grw5s2pf	1522	84	of	of	IN
cord-256444-grw5s2pf	1522	85	human	human	JJ
cord-256444-grw5s2pf	1522	86	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1522	87	OC43	OC43	NNP
cord-256444-grw5s2pf	1522	88	Phylogeny	Phylogeny	NNP
cord-256444-grw5s2pf	1522	89	of	of	IN
cord-256444-grw5s2pf	1522	90	antigenic	antigenic	JJ
cord-256444-grw5s2pf	1522	91	variants	variant	NNS
cord-256444-grw5s2pf	1522	92	of	of	IN
cord-256444-grw5s2pf	1522	93	avian	avian	JJ
cord-256444-grw5s2pf	1522	94	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1522	95	IBV	IBV	NNP
cord-256444-grw5s2pf	1522	96	.	.	.
cord-256444-grw5s2pf	1523	1	Virology	Virology	NNP
cord-256444-grw5s2pf	1523	2	Sequence	sequence	NN
cord-256444-grw5s2pf	1523	3	and	and	CC
cord-256444-grw5s2pf	1523	4	expression	expression	NN
cord-256444-grw5s2pf	1523	5	of	of	IN
cord-256444-grw5s2pf	1523	6	the	the	DT
cord-256444-grw5s2pf	1523	7	ns2	ns2	JJ
cord-256444-grw5s2pf	1523	8	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1523	9	leader	leader	NN
cord-256444-grw5s2pf	1523	10	RNA	RNA	NNP
cord-256444-grw5s2pf	1523	11	-	-	HYPH
cord-256444-grw5s2pf	1523	12	primed	prime	VBN
cord-256444-grw5s2pf	1523	13	transcription	transcription	NN
cord-256444-grw5s2pf	1523	14	:	:	:
cord-256444-grw5s2pf	1523	15	An	an	DT
cord-256444-grw5s2pf	1523	16	alternative	alternative	JJ
cord-256444-grw5s2pf	1523	17	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1523	18	:	:	:
cord-256444-grw5s2pf	1523	19	Organization	organization	NN
cord-256444-grw5s2pf	1523	20	,	,	,
cord-256444-grw5s2pf	1523	21	replication	replication	NN
cord-256444-grw5s2pf	1523	22	and	and	CC
cord-256444-grw5s2pf	1523	23	expression	expression	NN
cord-256444-grw5s2pf	1523	24	of	of	IN
cord-256444-grw5s2pf	1523	25	genome	genome	NN
cord-256444-grw5s2pf	1523	26	RNA	rna	NN
cord-256444-grw5s2pf	1523	27	recombination	recombination	NN
cord-256444-grw5s2pf	1523	28	in	in	IN
cord-256444-grw5s2pf	1523	29	animal	animal	NN
cord-256444-grw5s2pf	1523	30	and	and	CC
cord-256444-grw5s2pf	1523	31	plant	plant	NN
cord-256444-grw5s2pf	1523	32	viruses	virus	NNS
cord-256444-grw5s2pf	1524	1	Mouse	Mouse	NNP
cord-256444-grw5s2pf	1524	2	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1524	3	virus	virus	NN
cord-256444-grw5s2pf	1524	4	A59	A59	NNP
cord-256444-grw5s2pf	1524	5	:	:	:
cord-256444-grw5s2pf	1525	1	Messenger	Messenger	NNP
cord-256444-grw5s2pf	1525	2	RNA	RNA	NNP
cord-256444-grw5s2pf	1525	3	structure	structure	NN
cord-256444-grw5s2pf	1525	4	and	and	CC
cord-256444-grw5s2pf	1525	5	genetic	genetic	JJ
cord-256444-grw5s2pf	1525	6	localization	localization	NN
cord-256444-grw5s2pf	1525	7	of	of	IN
cord-256444-grw5s2pf	1525	8	the	the	DT
cord-256444-grw5s2pf	1525	9	sequence	sequence	NN
cord-256444-grw5s2pf	1525	10	divergence	divergence	NN
cord-256444-grw5s2pf	1525	11	from	from	IN
cord-256444-grw5s2pf	1525	12	the	the	DT
cord-256444-grw5s2pf	1525	13	hepatotropic	hepatotropic	NNP
cord-256444-grw5s2pf	1525	14	strain	strain	VBP
cord-256444-grw5s2pf	1525	15	MHV	MHV	NNP
cord-256444-grw5s2pf	1525	16	3	3	CD
cord-256444-grw5s2pf	1526	1	The	the	DT
cord-256444-grw5s2pf	1526	2	presence	presence	NN
cord-256444-grw5s2pf	1526	3	of	of	IN
cord-256444-grw5s2pf	1526	4	leader	leader	NN
cord-256444-grw5s2pf	1526	5	sequences	sequence	NNS
cord-256444-grw5s2pf	1526	6	in	in	IN
cord-256444-grw5s2pf	1526	7	the	the	DT
cord-256444-grw5s2pf	1526	8	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1526	9	of	of	IN
cord-256444-grw5s2pf	1526	10	mouse	mouse	NNP
cord-256444-grw5s2pf	1526	11	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1526	12	virus	virus	NN
cord-256444-grw5s2pf	1526	13	Characterization	characterization	NN
cord-256444-grw5s2pf	1526	14	of	of	IN
cord-256444-grw5s2pf	1526	15	leader	leader	NN
cord-256444-grw5s2pf	1526	16	RNA	RNA	NNP
cord-256444-grw5s2pf	1526	17	sequences	sequence	NNS
cord-256444-grw5s2pf	1526	18	on	on	IN
cord-256444-grw5s2pf	1526	19	the	the	DT
cord-256444-grw5s2pf	1526	20	virion	virion	NN
cord-256444-grw5s2pf	1526	21	and	and	CC
cord-256444-grw5s2pf	1526	22	mRNAs	mrnas	CD
cord-256444-grw5s2pf	1526	23	of	of	IN
cord-256444-grw5s2pf	1526	24	mouse	mouse	NNP
cord-256444-grw5s2pf	1526	25	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1526	26	virus	virus	NN
cord-256444-grw5s2pf	1526	27	-	-	:
cord-256444-grw5s2pf	1526	28	a	a	DT
cord-256444-grw5s2pf	1526	29	cytoplasmic	cytoplasmic	JJ
cord-256444-grw5s2pf	1526	30	RNA	RNA	NNP
cord-256444-grw5s2pf	1526	31	virus	virus	NN
cord-256444-grw5s2pf	1526	32	Recombination	recombination	NN
cord-256444-grw5s2pf	1526	33	between	between	IN
cord-256444-grw5s2pf	1526	34	nonsegmented	nonsegmented	NNP
cord-256444-grw5s2pf	1526	35	RNA	RNA	NNP
cord-256444-grw5s2pf	1526	36	genome8	genome8	NN
cord-256444-grw5s2pf	1526	37	of	of	IN
cord-256444-grw5s2pf	1526	38	murine	murine	JJ
cord-256444-grw5s2pf	1526	39	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1527	1	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1527	2	:	:	:
cord-256444-grw5s2pf	1528	1	A	a	DT
cord-256444-grw5s2pf	1528	2	jumping	jump	VBG
cord-256444-grw5s2pf	1528	3	RNA	RNA	NNP
cord-256444-grw5s2pf	1528	4	transcription	transcription	NN
cord-256444-grw5s2pf	1528	5	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1528	6	:	:	:
cord-256444-grw5s2pf	1529	1	How	how	WRB
cord-256444-grw5s2pf	1529	2	a	a	DT
cord-256444-grw5s2pf	1529	3	large	large	JJ
cord-256444-grw5s2pf	1529	4	RNA	RNA	NNP
cord-256444-grw5s2pf	1529	5	viral	viral	JJ
cord-256444-grw5s2pf	1529	6	genome	genome	NN
cord-256444-grw5s2pf	1529	7	is	be	VBZ
cord-256444-grw5s2pf	1529	8	replicated	replicate	VBN
cord-256444-grw5s2pf	1529	9	and	and	CC
cord-256444-grw5s2pf	1529	10	transcribed	transcribe	VBN
cord-256444-grw5s2pf	1529	11	Localization	Localization	NNP
cord-256444-grw5s2pf	1529	12	of	of	IN
cord-256444-grw5s2pf	1529	13	extensive	extensive	JJ
cord-256444-grw5s2pf	1529	14	deletions	deletion	NNS
cord-256444-grw5s2pf	1529	15	in	in	IN
cord-256444-grw5s2pf	1529	16	the	the	DT
cord-256444-grw5s2pf	1529	17	structural	structural	JJ
cord-256444-grw5s2pf	1529	18	genes	gene	NNS
cord-256444-grw5s2pf	1529	19	of	of	IN
cord-256444-grw5s2pf	1529	20	two	two	CD
cord-256444-grw5s2pf	1529	21	neurotropic	neurotropic	NNP
cord-256444-grw5s2pf	1529	22	variants	variant	NNS
cord-256444-grw5s2pf	1529	23	of	of	IN
cord-256444-grw5s2pf	1529	24	murine	murine	JJ
cord-256444-grw5s2pf	1529	25	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1529	26	JHM	JHM	NNP
cord-256444-grw5s2pf	1529	27	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1529	28	mRNA	mrna	NN
cord-256444-grw5s2pf	1529	29	synthesis	synthesis	NN
cord-256444-grw5s2pf	1529	30	:	:	:
cord-256444-grw5s2pf	1529	31	Identification	identification	NN
cord-256444-grw5s2pf	1529	32	of	of	IN
cord-256444-grw5s2pf	1529	33	novel	novel	JJ
cord-256444-grw5s2pf	1529	34	transcription	transcription	NN
cord-256444-grw5s2pf	1529	35	initiation	initiation	NN
cord-256444-grw5s2pf	1529	36	signals	signal	NNS
cord-256444-grw5s2pf	1529	37	which	which	WDT
cord-256444-grw5s2pf	1529	38	are	be	VBP
cord-256444-grw5s2pf	1529	39	differentially	differentially	RB
cord-256444-grw5s2pf	1529	40	regulated	regulate	VBN
cord-256444-grw5s2pf	1529	41	by	by	IN
cord-256444-grw5s2pf	1529	42	different	different	JJ
cord-256444-grw5s2pf	1529	43	leader	leader	NN
cord-256444-grw5s2pf	1529	44	sequences	sequence	NNS
cord-256444-grw5s2pf	1529	45	Sequence	Sequence	NNP
cord-256444-grw5s2pf	1529	46	analysis	analysis	NN
cord-256444-grw5s2pf	1529	47	of	of	IN
cord-256444-grw5s2pf	1529	48	the	the	DT
cord-256444-grw5s2pf	1529	49	bovine	bovine	JJ
cord-256444-grw5s2pf	1529	50	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1529	51	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1529	52	and	and	CC
cord-256444-grw5s2pf	1529	53	matrix	matrix	NN
cord-256444-grw5s2pf	1529	54	protein	protein	NN
cord-256444-grw5s2pf	1529	55	genes	gene	NNS
cord-256444-grw5s2pf	1529	56	Porcine	porcine	JJ
cord-256444-grw5s2pf	1529	57	respiratory	respiratory	JJ
cord-256444-grw5s2pf	1529	58	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1529	59	:	:	:
cord-256444-grw5s2pf	1529	60	Molecular	molecular	JJ
cord-256444-grw5s2pf	1529	61	features	feature	NNS
cord-256444-grw5s2pf	1529	62	and	and	CC
cord-256444-grw5s2pf	1529	63	virus	virus	NN
cord-256444-grw5s2pf	1529	64	-	-	HYPH
cord-256444-grw5s2pf	1529	65	host	host	NN
cord-256444-grw5s2pf	1529	66	interactions	interaction	NNS
cord-256444-grw5s2pf	1530	1	The	the	DT
cord-256444-grw5s2pf	1530	2	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1530	3	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1530	4	protein	protein	NN
cord-256444-grw5s2pf	1530	5	Single	single	JJ
cord-256444-grw5s2pf	1530	6	amino	amino	NN
cord-256444-grw5s2pf	1530	7	acid	acid	NN
cord-256444-grw5s2pf	1530	8	changes	change	NNS
cord-256444-grw5s2pf	1530	9	in	in	IN
cord-256444-grw5s2pf	1530	10	the	the	DT
cord-256444-grw5s2pf	1530	11	viral	viral	JJ
cord-256444-grw5s2pf	1530	12	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1530	13	M	m	CD
cord-256444-grw5s2pf	1530	14	affect	affect	NN
cord-256444-grw5s2pf	1530	15	induction	induction	NN
cord-256444-grw5s2pf	1530	16	of	of	IN
cord-256444-grw5s2pf	1530	17	alpha	alpha	NN
cord-256444-grw5s2pf	1530	18	interferon	interferon	NN
cord-256444-grw5s2pf	1530	19	by	by	IN
cord-256444-grw5s2pf	1530	20	the	the	DT
cord-256444-grw5s2pf	1530	21	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1530	22	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1530	23	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1530	24	virus	virus	NN
cord-256444-grw5s2pf	1530	25	Expression	expression	NN
cord-256444-grw5s2pf	1530	26	of	of	IN
cord-256444-grw5s2pf	1530	27	swine	swine	NN
cord-256444-grw5s2pf	1530	28	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1530	29	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1530	30	virus	virus	NN
cord-256444-grw5s2pf	1530	31	envelope	envelope	NN
cord-256444-grw5s2pf	1530	32	antigens	antigen	NNS
cord-256444-grw5s2pf	1530	33	on	on	IN
cord-256444-grw5s2pf	1530	34	the	the	DT
cord-256444-grw5s2pf	1530	35	surface	surface	NN
cord-256444-grw5s2pf	1530	36	of	of	IN
cord-256444-grw5s2pf	1530	37	infected	infected	JJ
cord-256444-grw5s2pf	1530	38	cells	cell	NNS
cord-256444-grw5s2pf	1530	39	:	:	:
cord-256444-grw5s2pf	1530	40	Epitopes	Epitopes	NNP
cord-256444-grw5s2pf	1530	41	externally	externally	RB
cord-256444-grw5s2pf	1530	42	exposed	expose	VBD
cord-256444-grw5s2pf	1530	43	Distinct	distinct	JJ
cord-256444-grw5s2pf	1530	44	structural	structural	JJ
cord-256444-grw5s2pf	1530	45	elements	element	NNS
cord-256444-grw5s2pf	1530	46	and	and	CC
cord-256444-grw5s2pf	1530	47	internal	internal	JJ
cord-256444-grw5s2pf	1530	48	entry	entry	NN
cord-256444-grw5s2pf	1530	49	of	of	IN
cord-256444-grw5s2pf	1530	50	ribosomes	ribosome	NNS
cord-256444-grw5s2pf	1530	51	in	in	IN
cord-256444-grw5s2pf	1530	52	mRNA3	mrna3	NN
cord-256444-grw5s2pf	1531	1	encoded	encode	VBN
cord-256444-grw5s2pf	1531	2	by	by	IN
cord-256444-grw5s2pf	1531	3	infectious	infectious	JJ
cord-256444-grw5s2pf	1531	4	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1531	5	virus	virus	NN
cord-256444-grw5s2pf	1532	1	The	the	DT
cord-256444-grw5s2pf	1532	2	complete	complete	JJ
cord-256444-grw5s2pf	1532	3	sequence	sequence	NN
cord-256444-grw5s2pf	1532	4	(	(	-LRB-
cord-256444-grw5s2pf	1532	5	22	22	CD
cord-256444-grw5s2pf	1532	6	kilobases	kilobase	NNS
cord-256444-grw5s2pf	1532	7	)	)	-RRB-
cord-256444-grw5s2pf	1532	8	of	of	IN
cord-256444-grw5s2pf	1532	9	murine	murine	JJ
cord-256444-grw5s2pf	1532	10	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1532	11	gene	gene	NN
cord-256444-grw5s2pf	1532	12	1	1	CD
cord-256444-grw5s2pf	1532	13	encoding	encode	VBG
cord-256444-grw5s2pf	1532	14	the	the	DT
cord-256444-grw5s2pf	1532	15	putative	putative	JJ
cord-256444-grw5s2pf	1532	16	proteases	protease	NNS
cord-256444-grw5s2pf	1532	17	and	and	CC
cord-256444-grw5s2pf	1532	18	RNA	RNA	NNP
cord-256444-grw5s2pf	1532	19	polymerase	polymerase	NN
cord-256444-grw5s2pf	1532	20	Synthesis	Synthesis	NNP
cord-256444-grw5s2pf	1532	21	of	of	IN
cord-256444-grw5s2pf	1532	22	virus	virus	NN
cord-256444-grw5s2pf	1532	23	-	-	HYPH
cord-256444-grw5s2pf	1532	24	specific	specific	JJ
cord-256444-grw5s2pf	1532	25	RNA	RNA	NNP
cord-256444-grw5s2pf	1532	26	in	in	IN
cord-256444-grw5s2pf	1532	27	permeabilized	permeabilized	JJ
cord-256444-grw5s2pf	1532	28	murine	murine	JJ
cord-256444-grw5s2pf	1532	29	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1532	30	-	-	HYPH
cord-256444-grw5s2pf	1532	31	infected	infect	VBN
cord-256444-grw5s2pf	1532	32	cells	cell	NNS
cord-256444-grw5s2pf	1533	1	Thevirus	Thevirus	NNP
cord-256444-grw5s2pf	1533	2	specific	specific	JJ
cord-256444-grw5s2pf	1533	3	intracellular	intracellular	JJ
cord-256444-grw5s2pf	1533	4	RNA	RNA	NNP
cord-256444-grw5s2pf	1533	5	species	specie	NNS
cord-256444-grw5s2pf	1533	6	of	of	IN
cord-256444-grw5s2pf	1533	7	two	two	CD
cord-256444-grw5s2pf	1533	8	murine	murine	JJ
cord-256444-grw5s2pf	1533	9	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1533	10	:	:	:
cord-256444-grw5s2pf	1534	1	MHV	MHV	NNP
cord-256444-grw5s2pf	1534	2	A59	A59	NNP
cord-256444-grw5s2pf	1534	3	and	and	CC
cord-256444-grw5s2pf	1534	4	MHV	MHV	NNP
cord-256444-grw5s2pf	1534	5	-	-	HYPH
cord-256444-grw5s2pf	1534	6	JHM	JHM	NNP
cord-256444-grw5s2pf	1534	7	Genetic	genetic	JJ
cord-256444-grw5s2pf	1534	8	analysis	analysis	NN
cord-256444-grw5s2pf	1534	9	of	of	IN
cord-256444-grw5s2pf	1534	10	murine	murine	JJ
cord-256444-grw5s2pf	1534	11	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1534	12	virus	virus	NN
cord-256444-grw5s2pf	1534	13	strain	strain	NN
cord-256444-grw5s2pf	1534	14	JHM	JHM	NNP
cord-256444-grw5s2pf	1534	15	Cell	Cell	NNP
cord-256444-grw5s2pf	1534	16	-	-	HYPH
cord-256444-grw5s2pf	1534	17	free	free	JJ
cord-256444-grw5s2pf	1534	18	translation	translation	NN
cord-256444-grw5s2pf	1534	19	of	of	IN
cord-256444-grw5s2pf	1534	20	murine	murine	JJ
cord-256444-grw5s2pf	1534	21	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1534	22	RNA	RNA	NNP
cord-256444-grw5s2pf	1534	23	Detection	Detection	NNP
cord-256444-grw5s2pf	1534	24	of	of	IN
cord-256444-grw5s2pf	1534	25	a	a	DT
cord-256444-grw5s2pf	1534	26	murine	murine	JJ
cord-256444-grw5s2pf	1534	27	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1534	28	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	1534	29	protein	protein	NN
cord-256444-grw5s2pf	1534	30	encoded	encode	VBN
cord-256444-grw5s2pf	1534	31	in	in	IN
cord-256444-grw5s2pf	1534	32	a	a	DT
cord-256444-grw5s2pf	1534	33	downstream	downstream	JJ
cord-256444-grw5s2pf	1534	34	open	open	JJ
cord-256444-grw5s2pf	1534	35	reading	reading	NN
cord-256444-grw5s2pf	1534	36	frame	frame	NN
cord-256444-grw5s2pf	1534	37	Differential	differential	NN
cord-256444-grw5s2pf	1534	38	in	in	IN
cord-256444-grw5s2pf	1534	39	vitro	vitro	FW
cord-256444-grw5s2pf	1534	40	inhibition	inhibition	NN
cord-256444-grw5s2pf	1534	41	of	of	IN
cord-256444-grw5s2pf	1534	42	feline	feline	JJ
cord-256444-grw5s2pf	1534	43	enteric	enteric	JJ
cord-256444-grw5s2pf	1534	44	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1534	45	and	and	CC
cord-256444-grw5s2pf	1534	46	feline	feline	JJ
cord-256444-grw5s2pf	1534	47	infectious	infectious	JJ
cord-256444-grw5s2pf	1534	48	peritonitis	peritonitis	NN
cord-256444-grw5s2pf	1534	49	virus	virus	NN
cord-256444-grw5s2pf	1534	50	by	by	IN
cord-256444-grw5s2pf	1534	51	actinomycin	actinomycin	NNS
cord-256444-grw5s2pf	1534	52	D	D	NNP
cord-256444-grw5s2pf	1534	53	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1534	54	IBV	IBV	NNP
cord-256444-grw5s2pf	1534	55	-	-	HYPH
cord-256444-grw5s2pf	1534	56	induced	induce	VBN
cord-256444-grw5s2pf	1534	57	membrane	membrane	NN
cord-256444-grw5s2pf	1534	58	fusion	fusion	NN
cord-256444-grw5s2pf	1534	59	occurs	occur	VBZ
cord-256444-grw5s2pf	1534	60	at	at	IN
cord-256444-grw5s2pf	1534	61	near	near	RB
cord-256444-grw5s2pf	1534	62	-	-	HYPH
cord-256444-grw5s2pf	1534	63	neutral	neutral	JJ
cord-256444-grw5s2pf	1534	64	pH	pH	NNP
cord-256444-grw5s2pf	1534	65	RNArecombination	RNArecombination	NNP
cord-256444-grw5s2pf	1534	66	in	in	IN
cord-256444-grw5s2pf	1534	67	a	a	DT
cord-256444-grw5s2pf	1534	68	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1534	69	:	:	:
cord-256444-grw5s2pf	1535	1	Recombination	recombination	NN
cord-256444-grw5s2pf	1535	2	between	between	IN
cord-256444-grw5s2pf	1535	3	viral	viral	JJ
cord-256444-grw5s2pf	1535	4	genomic	genomic	JJ
cord-256444-grw5s2pf	1535	5	RNA	RNA	NNP
cord-256444-grw5s2pf	1535	6	and	and	CC
cord-256444-grw5s2pf	1535	7	transfected	transfecte	VBN
cord-256444-grw5s2pf	1535	8	RNA	RNA	NNP
cord-256444-grw5s2pf	1535	9	fragments	fragment	NNS
cord-256444-grw5s2pf	1535	10	Requirement	Requirement	NNP
cord-256444-grw5s2pf	1535	11	of	of	IN
cord-256444-grw5s2pf	1535	12	the	the	DT
cord-256444-grw5s2pf	1535	13	5'-end	5'-end	CD
cord-256444-grw5s2pf	1535	14	genomic	genomic	JJ
cord-256444-grw5s2pf	1535	15	sequence	sequence	NN
cord-256444-grw5s2pf	1535	16	as	as	IN
cord-256444-grw5s2pf	1535	17	an	an	DT
cord-256444-grw5s2pf	1535	18	upstream	upstream	JJ
cord-256444-grw5s2pf	1535	19	cis	cis	NNP
cord-256444-grw5s2pf	1535	20	-	-	HYPH
cord-256444-grw5s2pf	1535	21	acting	act	VBG
cord-256444-grw5s2pf	1535	22	element	element	NN
cord-256444-grw5s2pf	1535	23	for	for	IN
cord-256444-grw5s2pf	1535	24	coronavirus	coronavirus	NNP
cord-256444-grw5s2pf	1535	25	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1535	26	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1535	27	transcription	transcription	NNP
cord-256444-grw5s2pf	1535	28	A	a	DT
cord-256444-grw5s2pf	1535	29	cis	cis	NNP
cord-256444-grw5s2pf	1535	30	-	-	HYPH
cord-256444-grw5s2pf	1535	31	acting	act	VBG
cord-256444-grw5s2pf	1535	32	viral	viral	JJ
cord-256444-grw5s2pf	1535	33	protein	protein	NN
cord-256444-grw5s2pf	1535	34	is	be	VBZ
cord-256444-grw5s2pf	1535	35	not	not	RB
cord-256444-grw5s2pf	1535	36	required	require	VBN
cord-256444-grw5s2pf	1535	37	for	for	IN
cord-256444-grw5s2pf	1535	38	the	the	DT
cord-256444-grw5s2pf	1535	39	replication	replication	NN
cord-256444-grw5s2pf	1535	40	of	of	IN
cord-256444-grw5s2pf	1535	41	a	a	DT
cord-256444-grw5s2pf	1535	42	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1535	43	defective	defective	JJ
cord-256444-grw5s2pf	1535	44	-	-	HYPH
cord-256444-grw5s2pf	1535	45	interfering	interfere	VBG
cord-256444-grw5s2pf	1535	46	RNA	RNA	NNP
cord-256444-grw5s2pf	1535	47	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1535	48	defective	defective	JJ
cord-256444-grw5s2pf	1535	49	-	-	HYPH
cord-256444-grw5s2pf	1535	50	interfering	interfere	VBG
cord-256444-grw5s2pf	1535	51	RNA	RNA	NNP
cord-256444-grw5s2pf	1535	52	as	as	IN
cord-256444-grw5s2pf	1535	53	an	an	DT
cord-256444-grw5s2pf	1535	54	expression	expression	NN
cord-256444-grw5s2pf	1535	55	vector	vector	NN
cord-256444-grw5s2pf	1535	56	:	:	:
cord-256444-grw5s2pf	1535	57	The	the	DT
cord-256444-grw5s2pf	1535	58	generation	generation	NN
cord-256444-grw5s2pf	1535	59	of	of	IN
cord-256444-grw5s2pf	1535	60	a	a	DT
cord-256444-grw5s2pf	1535	61	pseudorecombinant	pseudorecombinant	JJ
cord-256444-grw5s2pf	1535	62	mouse	mouse	NN
cord-256444-grw5s2pf	1535	63	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1535	64	virus	virus	NN
cord-256444-grw5s2pf	1535	65	expressing	express	VBG
cord-256444-grw5s2pf	1535	66	hemagglutinin	hemagglutinin	NN
cord-256444-grw5s2pf	1535	67	-	-	HYPH
cord-256444-grw5s2pf	1535	68	esterase	esterase	NN
cord-256444-grw5s2pf	1535	69	Deletion	deletion	NN
cord-256444-grw5s2pf	1535	70	mapping	mapping	NN
cord-256444-grw5s2pf	1535	71	of	of	IN
cord-256444-grw5s2pf	1535	72	a	a	DT
cord-256444-grw5s2pf	1535	73	mouse	mouse	NN
cord-256444-grw5s2pf	1535	74	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1535	75	virus	virus	NN
cord-256444-grw5s2pf	1535	76	defectiveinterfering	defectiveinterfering	NNP
cord-256444-grw5s2pf	1535	77	RNA	RNA	NNP
cord-256444-grw5s2pf	1535	78	reveals	reveal	VBZ
cord-256444-grw5s2pf	1535	79	the	the	DT
cord-256444-grw5s2pf	1535	80	requirement	requirement	NN
cord-256444-grw5s2pf	1535	81	of	of	IN
cord-256444-grw5s2pf	1535	82	an	an	DT
cord-256444-grw5s2pf	1535	83	internal	internal	JJ
cord-256444-grw5s2pf	1535	84	and	and	CC
cord-256444-grw5s2pf	1535	85	discontiguous	discontiguous	JJ
cord-256444-grw5s2pf	1535	86	sequence	sequence	NN
cord-256444-grw5s2pf	1535	87	for	for	IN
cord-256444-grw5s2pf	1535	88	replication	replication	NN
cord-256444-grw5s2pf	1535	89	Identification	identification	NN
cord-256444-grw5s2pf	1535	90	of	of	IN
cord-256444-grw5s2pf	1535	91	the	the	DT
cord-256444-grw5s2pf	1535	92	cis	cis	NNP
cord-256444-grw5s2pf	1535	93	-	-	HYPH
cord-256444-grw5s2pf	1535	94	acting	act	VBG
cord-256444-grw5s2pf	1535	95	signal	signal	NN
cord-256444-grw5s2pf	1535	96	for	for	IN
cord-256444-grw5s2pf	1535	97	minus	minus	JJ
cord-256444-grw5s2pf	1535	98	-	-	HYPH
cord-256444-grw5s2pf	1535	99	strand	strand	NN
cord-256444-grw5s2pf	1535	100	RNA	RNA	NNP
cord-256444-grw5s2pf	1535	101	synthesis	synthesis	NN
cord-256444-grw5s2pf	1535	102	of	of	IN
cord-256444-grw5s2pf	1535	103	a	a	DT
cord-256444-grw5s2pf	1535	104	murine	murine	JJ
cord-256444-grw5s2pf	1535	105	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1535	106	:	:	:
cord-256444-grw5s2pf	1536	1	Implications	implication	NNS
cord-256444-grw5s2pf	1536	2	for	for	IN
cord-256444-grw5s2pf	1536	3	the	the	DT
cord-256444-grw5s2pf	1536	4	role	role	NN
cord-256444-grw5s2pf	1536	5	of	of	IN
cord-256444-grw5s2pf	1536	6	minus	minus	JJ
cord-256444-grw5s2pf	1536	7	-	-	HYPH
cord-256444-grw5s2pf	1536	8	strand	strand	NN
cord-256444-grw5s2pf	1536	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1536	10	in	in	IN
cord-256444-grw5s2pf	1536	11	RNA	RNA	NNP
cord-256444-grw5s2pf	1536	12	replication	replication	NN
cord-256444-grw5s2pf	1536	13	and	and	CC
cord-256444-grw5s2pf	1536	14	transcription	transcription	NN
cord-256444-grw5s2pf	1537	1	The	the	DT
cord-256444-grw5s2pf	1537	2	3	3	CD
cord-256444-grw5s2pf	1537	3	'	'	POS
cord-256444-grw5s2pf	1537	4	untranslated	untranslated	JJ
cord-256444-grw5s2pf	1537	5	region	region	NN
cord-256444-grw5s2pf	1537	6	of	of	IN
cord-256444-grw5s2pf	1537	7	the	the	DT
cord-256444-grw5s2pf	1537	8	coronaviral	coronaviral	NNP
cord-256444-grw5s2pf	1537	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1537	10	is	be	VBZ
cord-256444-grw5s2pf	1537	11	required	require	VBN
cord-256444-grw5s2pf	1537	12	for	for	IN
cord-256444-grw5s2pf	1537	13	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1537	14	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1537	15	transcription	transcription	NN
cord-256444-grw5s2pf	1537	16	from	from	IN
cord-256444-grw5s2pf	1537	17	a	a	DT
cord-256444-grw5s2pf	1537	18	defectiveinterfering	defectiveinterfering	NN
cord-256444-grw5s2pf	1537	19	RNA	RNA	NNP
cord-256444-grw5s2pf	1537	20	Characterisation	Characterisation	NNP
cord-256444-grw5s2pf	1537	21	and	and	CC
cord-256444-grw5s2pf	1537	22	mutational	mutational	JJ
cord-256444-grw5s2pf	1537	23	analysis	analysis	NN
cord-256444-grw5s2pf	1537	24	of	of	IN
cord-256444-grw5s2pf	1537	25	an	an	DT
cord-256444-grw5s2pf	1537	26	ORF	ORF	NNP
cord-256444-grw5s2pf	1537	27	la	la	NN
cord-256444-grw5s2pf	1537	28	-	-	HYPH
cord-256444-grw5s2pf	1537	29	encoding	encode	VBG
cord-256444-grw5s2pf	1537	30	proteinase	proteinase	NN
cord-256444-grw5s2pf	1537	31	domain	domain	NN
cord-256444-grw5s2pf	1537	32	responsible	responsible	JJ
cord-256444-grw5s2pf	1537	33	for	for	IN
cord-256444-grw5s2pf	1537	34	proteolytic	proteolytic	JJ
cord-256444-grw5s2pf	1537	35	processing	processing	NN
cord-256444-grw5s2pf	1537	36	of	of	IN
cord-256444-grw5s2pf	1537	37	the	the	DT
cord-256444-grw5s2pf	1537	38	infectious	infectious	JJ
cord-256444-grw5s2pf	1537	39	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1537	40	virus	virus	NN
cord-256444-grw5s2pf	1537	41	l	l	NN
cord-256444-grw5s2pf	1537	42	d	d	NNP
cord-256444-grw5s2pf	1537	43	l	l	NNP
cord-256444-grw5s2pf	1537	44	b	b	NNP
cord-256444-grw5s2pf	1537	45	polyprotein	polyprotein	NNP
cord-256444-grw5s2pf	1537	46	Identification	Identification	NNP
cord-256444-grw5s2pf	1537	47	of	of	IN
cord-256444-grw5s2pf	1537	48	two	two	CD
cord-256444-grw5s2pf	1537	49	new	new	JJ
cord-256444-grw5s2pf	1537	50	polypeptides	polypeptide	NNS
cord-256444-grw5s2pf	1537	51	encoded	encode	VBN
cord-256444-grw5s2pf	1537	52	by	by	IN
cord-256444-grw5s2pf	1537	53	mRNA5	mRNA5	NNS
cord-256444-grw5s2pf	1537	54	of	of	IN
cord-256444-grw5s2pf	1537	55	the	the	DT
cord-256444-grw5s2pf	1537	56	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1537	57	infectious	infectious	JJ
cord-256444-grw5s2pf	1537	58	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1537	59	virus	virus	NN
cord-256444-grw5s2pf	1537	60	Internal	internal	JJ
cord-256444-grw5s2pf	1537	61	entry	entry	NN
cord-256444-grw5s2pf	1537	62	of	of	IN
cord-256444-grw5s2pf	1537	63	ribosomes	ribosome	NNS
cord-256444-grw5s2pf	1537	64	on	on	IN
cord-256444-grw5s2pf	1537	65	a	a	DT
cord-256444-grw5s2pf	1537	66	tricistronic	tricistronic	NNP
cord-256444-grw5s2pf	1537	67	mRNA	mrna	NN
cord-256444-grw5s2pf	1537	68	encoded	encode	VBN
cord-256444-grw5s2pf	1537	69	by	by	IN
cord-256444-grw5s2pf	1537	70	infectious	infectious	JJ
cord-256444-grw5s2pf	1537	71	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1537	72	virus	virus	NN
cord-256444-grw5s2pf	1538	1	A	a	DT
cord-256444-grw5s2pf	1538	2	polycistronic	polycistronic	JJ
cord-256444-grw5s2pf	1538	3	mRNA	mrna	NN
cord-256444-grw5s2pf	1538	4	specified	specify	VBN
cord-256444-grw5s2pf	1538	5	by	by	IN
cord-256444-grw5s2pf	1538	6	the	the	DT
cord-256444-grw5s2pf	1538	7	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1538	8	infectious	infectious	JJ
cord-256444-grw5s2pf	1538	9	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1538	10	virus	virus	NN
cord-256444-grw5s2pf	1539	1	A	a	DT
cord-256444-grw5s2pf	1539	2	100-kilodalton	100-kilodalton	CD
cord-256444-grw5s2pf	1539	3	polypeptide	polypeptide	NN
cord-256444-grw5s2pf	1539	4	encoded	encode	VBN
cord-256444-grw5s2pf	1539	5	by	by	IN
cord-256444-grw5s2pf	1539	6	open	open	JJ
cord-256444-grw5s2pf	1539	7	reading	reading	NN
cord-256444-grw5s2pf	1539	8	frame	frame	NN
cord-256444-grw5s2pf	1540	1	(	(	-LRB-
cord-256444-grw5s2pf	1540	2	ORF	ORF	NNP
cord-256444-grw5s2pf	1540	3	)	)	-RRB-
cord-256444-grw5s2pf	1540	4	l	l	NNP
cord-256444-grw5s2pf	1540	5	b	b	NNP
cord-256444-grw5s2pf	1540	6	of	of	IN
cord-256444-grw5s2pf	1540	7	the	the	DT
cord-256444-grw5s2pf	1540	8	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1540	9	infectious	infectious	JJ
cord-256444-grw5s2pf	1540	10	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1540	11	virus	virus	NN
cord-256444-grw5s2pf	1540	12	is	be	VBZ
cord-256444-grw5s2pf	1540	13	processed	process	VBN
cord-256444-grw5s2pf	1540	14	by	by	IN
cord-256444-grw5s2pf	1540	15	ORF	ORF	NNP
cord-256444-grw5s2pf	1540	16	la	la	NNP
cord-256444-grw5s2pf	1540	17	products	product	NNS
cord-256444-grw5s2pf	1540	18	0-glycosylation	0-glycosylation	CD
cord-256444-grw5s2pf	1540	19	of	of	IN
cord-256444-grw5s2pf	1540	20	the	the	DT
cord-256444-grw5s2pf	1540	21	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1540	22	M	M	NNP
cord-256444-grw5s2pf	1540	23	protein	protein	NN
cord-256444-grw5s2pf	1540	24	.	.	.
cord-256444-grw5s2pf	1541	1	Differential	differential	JJ
cord-256444-grw5s2pf	1541	2	localization	localization	NN
cord-256444-grw5s2pf	1541	3	of	of	IN
cord-256444-grw5s2pf	1541	4	sialyltransferases	sialyltransferase	NNS
cord-256444-grw5s2pf	1541	5	in	in	IN
cord-256444-grw5s2pf	1541	6	N	N	NNP
cord-256444-grw5s2pf	1541	7	-	-	:
cord-256444-grw5s2pf	1541	8	and	and	CC
cord-256444-grw5s2pf	1541	9	0-linked	0-linked	CD
cord-256444-grw5s2pf	1541	10	glycosylation	glycosylation	NN
cord-256444-grw5s2pf	1541	11	Membrane	membrane	NN
cord-256444-grw5s2pf	1541	12	assembly	assembly	NN
cord-256444-grw5s2pf	1541	13	of	of	IN
cord-256444-grw5s2pf	1541	14	the	the	DT
cord-256444-grw5s2pf	1541	15	triple	triple	RB
cord-256444-grw5s2pf	1541	16	-	-	HYPH
cord-256444-grw5s2pf	1541	17	spanning	span	VBG
cord-256444-grw5s2pf	1541	18	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1541	19	M	m	NN
cord-256444-grw5s2pf	1541	20	protein	protein	NN
cord-256444-grw5s2pf	1541	21	.	.	.
cord-256444-grw5s2pf	1542	1	Individual	individual	JJ
cord-256444-grw5s2pf	1542	2	transmembrane	transmembrane	NN
cord-256444-grw5s2pf	1542	3	domains	domain	NNS
cord-256444-grw5s2pf	1542	4	show	show	VBP
cord-256444-grw5s2pf	1542	5	preferred	preferred	JJ
cord-256444-grw5s2pf	1542	6	orientation	orientation	NN
cord-256444-grw5s2pf	1543	1	The	the	DT
cord-256444-grw5s2pf	1543	2	cytoplasmic	cytoplasmic	JJ
cord-256444-grw5s2pf	1543	3	tail	tail	NN
cord-256444-grw5s2pf	1543	4	of	of	IN
cord-256444-grw5s2pf	1543	5	mouse	mouse	NN
cord-256444-grw5s2pf	1543	6	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1543	7	virus	virus	NN
cord-256444-grw5s2pf	1543	8	M	M	NNP
cord-256444-grw5s2pf	1543	9	protein	protein	NN
cord-256444-grw5s2pf	1543	10	is	be	VBZ
cord-256444-grw5s2pf	1543	11	essential	essential	JJ
cord-256444-grw5s2pf	1543	12	but	but	CC
cord-256444-grw5s2pf	1543	13	not	not	RB
cord-256444-grw5s2pf	1543	14	sufficient	sufficient	JJ
cord-256444-grw5s2pf	1543	15	for	for	IN
cord-256444-grw5s2pf	1543	16	its	-PRON-	PRP$
cord-256444-grw5s2pf	1543	17	retention	retention	NN
cord-256444-grw5s2pf	1543	18	in	in	IN
cord-256444-grw5s2pf	1543	19	the	the	DT
cord-256444-grw5s2pf	1543	20	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1543	21	complex	complex	JJ
cord-256444-grw5s2pf	1543	22	Oligomerization	Oligomerization	NNP
cord-256444-grw5s2pf	1543	23	of	of	IN
cord-256444-grw5s2pf	1543	24	a	a	DT
cord-256444-grw5s2pf	1543	25	trans	trans	NNP
cord-256444-grw5s2pf	1543	26	-	-	NNP
cord-256444-grw5s2pf	1543	27	GolgVtrans	GolgVtrans	NNP
cord-256444-grw5s2pf	1543	28	-	-	HYPH
cord-256444-grw5s2pf	1543	29	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1543	30	network	network	NN
cord-256444-grw5s2pf	1543	31	retained	retain	VBD
cord-256444-grw5s2pf	1543	32	protein	protein	NN
cord-256444-grw5s2pf	1543	33	occurs	occur	VBZ
cord-256444-grw5s2pf	1543	34	in	in	IN
cord-256444-grw5s2pf	1543	35	the	the	DT
cord-256444-grw5s2pf	1543	36	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1543	37	complex	complex	NN
cord-256444-grw5s2pf	1543	38	and	and	CC
cord-256444-grw5s2pf	1543	39	may	may	MD
cord-256444-grw5s2pf	1543	40	be	be	VB
cord-256444-grw5s2pf	1543	41	part	part	NN
cord-256444-grw5s2pf	1543	42	of	of	IN
cord-256444-grw5s2pf	1543	43	its	-PRON-	PRP$
cord-256444-grw5s2pf	1543	44	retention	retention	NN
cord-256444-grw5s2pf	1543	45	Intracellular	Intracellular	NNP
cord-256444-grw5s2pf	1543	46	and	and	CC
cord-256444-grw5s2pf	1543	47	in	in	IN
cord-256444-grw5s2pf	1543	48	vitro	vitro	FW
cord-256444-grw5s2pf	1543	49	-	-	HYPH
cord-256444-grw5s2pf	1543	50	translated	translate	VBN
cord-256444-grw5s2pf	1543	51	27-kDa	27-kda	CD
cord-256444-grw5s2pf	1543	52	proteins	protein	NNS
cord-256444-grw5s2pf	1543	53	contain	contain	VBP
cord-256444-grw5s2pf	1543	54	the	the	DT
cord-256444-grw5s2pf	1543	55	3C	3c	NN
cord-256444-grw5s2pf	1543	56	-	-	HYPH
cord-256444-grw5s2pf	1543	57	like	like	JJ
cord-256444-grw5s2pf	1543	58	proteinase	proteinase	NN
cord-256444-grw5s2pf	1543	59	activity	activity	NN
cord-256444-grw5s2pf	1543	60	of	of	IN
cord-256444-grw5s2pf	1543	61	the	the	DT
cord-256444-grw5s2pf	1543	62	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1543	63	MHV	mhv	NN
cord-256444-grw5s2pf	1543	64	-	-	HYPH
cord-256444-grw5s2pf	1543	65	ASS	ass	NN
cord-256444-grw5s2pf	1543	66	Identification	identification	NN
cord-256444-grw5s2pf	1543	67	and	and	CC
cord-256444-grw5s2pf	1543	68	characterization	characterization	NN
cord-256444-grw5s2pf	1543	69	of	of	IN
cord-256444-grw5s2pf	1543	70	a	a	DT
cord-256444-grw5s2pf	1543	71	serine	serine	NN
cord-256444-grw5s2pf	1543	72	-	-	HYPH
cord-256444-grw5s2pf	1543	73	like	like	JJ
cord-256444-grw5s2pf	1543	74	proteinase	proteinase	NN
cord-256444-grw5s2pf	1543	75	of	of	IN
cord-256444-grw5s2pf	1543	76	the	the	DT
cord-256444-grw5s2pf	1543	77	murine	murine	JJ
cord-256444-grw5s2pf	1543	78	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1543	79	MHV	MHV	NNP
cord-256444-grw5s2pf	1543	80	-	-	HYPH
cord-256444-grw5s2pf	1543	81	A59	A59	NNP
cord-256444-grw5s2pf	1543	82	Primary	primary	JJ
cord-256444-grw5s2pf	1543	83	structure	structure	NN
cord-256444-grw5s2pf	1543	84	of	of	IN
cord-256444-grw5s2pf	1543	85	the	the	DT
cord-256444-grw5s2pf	1543	86	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1543	87	E2	e2	NN
cord-256444-grw5s2pf	1543	88	of	of	IN
cord-256444-grw5s2pf	1543	89	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1543	90	MHV	MHV	NNP
cord-256444-grw5s2pf	1543	91	-	-	HYPH
cord-256444-grw5s2pf	1543	92	A59	A59	NNP
cord-256444-grw5s2pf	1543	93	and	and	CC
cord-256444-grw5s2pf	1543	94	identification	identification	NN
cord-256444-grw5s2pf	1543	95	of	of	IN
cord-256444-grw5s2pf	1543	96	the	the	DT
cord-256444-grw5s2pf	1543	97	trypsin	trypsin	NN
cord-256444-grw5s2pf	1543	98	cleavage	cleavage	NN
cord-256444-grw5s2pf	1543	99	site	site	NN
cord-256444-grw5s2pf	1543	100	.	.	.
cord-256444-grw5s2pf	1544	1	Virology	Virology	NNP
cord-256444-grw5s2pf	1544	2	Sequence	sequence	NN
cord-256444-grw5s2pf	1544	3	of	of	IN
cord-256444-grw5s2pf	1544	4	mouse	mouse	NN
cord-256444-grw5s2pf	1545	1	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1545	2	virus	virus	NN
cord-256444-grw5s2pf	1545	3	A59	A59	NNP
cord-256444-grw5s2pf	1545	4	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1546	1	2	2	LS
cord-256444-grw5s2pf	1546	2	:	:	:
cord-256444-grw5s2pf	1546	3	Indications	indication	NNS
cord-256444-grw5s2pf	1546	4	for	for	IN
cord-256444-grw5s2pf	1546	5	RNA	rna	NN
cord-256444-grw5s2pf	1546	6	-	-	HYPH
cord-256444-grw5s2pf	1546	7	recombination	recombination	NN
cord-256444-grw5s2pf	1546	8	between	between	IN
cord-256444-grw5s2pf	1546	9	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1546	10	and	and	CC
cord-256444-grw5s2pf	1546	11	influenza	influenza	NN
cord-256444-grw5s2pf	1546	12	C	c	NN
cord-256444-grw5s2pf	1546	13	virus	virus	NN
cord-256444-grw5s2pf	1546	14	Amino	amino	NN
cord-256444-grw5s2pf	1546	15	acid	acid	NN
cord-256444-grw5s2pf	1546	16	sequence	sequence	NN
cord-256444-grw5s2pf	1546	17	of	of	IN
cord-256444-grw5s2pf	1546	18	a	a	DT
cord-256444-grw5s2pf	1546	19	conserved	conserve	VBN
cord-256444-grw5s2pf	1546	20	neutralizing	neutralize	VBG
cord-256444-grw5s2pf	1546	21	epitope	epitope	NN
cord-256444-grw5s2pf	1546	22	of	of	IN
cord-256444-grw5s2pf	1546	23	murine	murine	JJ
cord-256444-grw5s2pf	1546	24	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1546	25	Replication	Replication	NNP
cord-256444-grw5s2pf	1546	26	of	of	IN
cord-256444-grw5s2pf	1546	27	synthetic	synthetic	JJ
cord-256444-grw5s2pf	1546	28	defective	defective	JJ
cord-256444-grw5s2pf	1546	29	interfering	interfere	VBG
cord-256444-grw5s2pf	1546	30	RNAs	rna	NNS
cord-256444-grw5s2pf	1546	31	derived	derive	VBN
cord-256444-grw5s2pf	1546	32	from	from	IN
cord-256444-grw5s2pf	1546	33	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1546	34	mouse	mouse	NN
cord-256444-grw5s2pf	1546	35	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1546	36	virus	virus	NN
cord-256444-grw5s2pf	1546	37	-	-	:
cord-256444-grw5s2pf	1546	38	A59	A59	NNP
cord-256444-grw5s2pf	1546	39	Characterization	characterization	NN
cord-256444-grw5s2pf	1546	40	of	of	IN
cord-256444-grw5s2pf	1546	41	two	two	CD
cord-256444-grw5s2pf	1546	42	temperature	temperature	NN
cord-256444-grw5s2pf	1546	43	-	-	HYPH
cord-256444-grw5s2pf	1546	44	sensitive	sensitive	JJ
cord-256444-grw5s2pf	1546	45	mutants	mutant	NNS
cord-256444-grw5s2pf	1546	46	of	of	IN
cord-256444-grw5s2pf	1546	47	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1546	48	mouse	mouse	NN
cord-256444-grw5s2pf	1546	49	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1546	50	virus	virus	NN
cord-256444-grw5s2pf	1546	51	strain	strain	VBP
cord-256444-grw5s2pf	1546	52	A59	A59	NNP
cord-256444-grw5s2pf	1546	53	with	with	IN
cord-256444-grw5s2pf	1546	54	maturation	maturation	NN
cord-256444-grw5s2pf	1546	55	defects	defect	NNS
cord-256444-grw5s2pf	1546	56	in	in	IN
cord-256444-grw5s2pf	1546	57	the	the	DT
cord-256444-grw5s2pf	1546	58	spike	spike	NN
cord-256444-grw5s2pf	1546	59	protein	protein	NN
cord-256444-grw5s2pf	1546	60	A	a	DT
cord-256444-grw5s2pf	1546	61	specific	specific	JJ
cord-256444-grw5s2pf	1546	62	transmembrane	transmembrane	NN
cord-256444-grw5s2pf	1546	63	domain	domain	NN
cord-256444-grw5s2pf	1546	64	of	of	IN
cord-256444-grw5s2pf	1546	65	a	a	DT
cord-256444-grw5s2pf	1546	66	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1546	67	E	e	NN
cord-256444-grw5s2pf	1546	68	l	l	NN
cord-256444-grw5s2pf	1546	69	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1546	70	is	be	VBZ
cord-256444-grw5s2pf	1546	71	required	require	VBN
cord-256444-grw5s2pf	1546	72	for	for	IN
cord-256444-grw5s2pf	1546	73	its	-PRON-	PRP$
cord-256444-grw5s2pf	1546	74	retention	retention	NN
cord-256444-grw5s2pf	1546	75	in	in	IN
cord-256444-grw5s2pf	1546	76	the	the	DT
cord-256444-grw5s2pf	1546	77	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1546	78	region	region	NN
cord-256444-grw5s2pf	1547	1	The	the	DT
cord-256444-grw5s2pf	1547	2	E	e	NN
cord-256444-grw5s2pf	1547	3	l	l	NN
cord-256444-grw5s2pf	1547	4	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1547	5	of	of	IN
cord-256444-grw5s2pf	1547	6	an	an	DT
cord-256444-grw5s2pf	1547	7	avian	avian	JJ
cord-256444-grw5s2pf	1547	8	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1547	9	is	be	VBZ
cord-256444-grw5s2pf	1547	10	targeted	target	VBN
cord-256444-grw5s2pf	1547	11	to	to	IN
cord-256444-grw5s2pf	1547	12	the	the	DT
cord-256444-grw5s2pf	1547	13	cis	cis	NNP
cord-256444-grw5s2pf	1547	14	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1547	15	complex	complex	NNP
cord-256444-grw5s2pf	1547	16	Retention	Retention	NNP
cord-256444-grw5s2pf	1547	17	of	of	IN
cord-256444-grw5s2pf	1547	18	a	a	DT
cord-256444-grw5s2pf	1547	19	cis	cis	NNP
cord-256444-grw5s2pf	1547	20	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1547	21	protein	protein	NN
cord-256444-grw5s2pf	1547	22	requires	require	VBZ
cord-256444-grw5s2pf	1547	23	polar	polar	JJ
cord-256444-grw5s2pf	1547	24	residues	residue	NNS
cord-256444-grw5s2pf	1547	25	on	on	IN
cord-256444-grw5s2pf	1547	26	one	one	CD
cord-256444-grw5s2pf	1547	27	face	face	NN
cord-256444-grw5s2pf	1547	28	of	of	IN
cord-256444-grw5s2pf	1547	29	a	a	DT
cord-256444-grw5s2pf	1547	30	predicted	predict	VBN
cord-256444-grw5s2pf	1547	31	alpha	alpha	NN
cord-256444-grw5s2pf	1547	32	-	-	NN
cord-256444-grw5s2pf	1547	33	helix	helix	NN
cord-256444-grw5s2pf	1547	34	in	in	IN
cord-256444-grw5s2pf	1547	35	the	the	DT
cord-256444-grw5s2pf	1547	36	transmembrane	transmembrane	NN
cord-256444-grw5s2pf	1547	37	domain	domain	NN
cord-256444-grw5s2pf	1547	38	Two	two	CD
cord-256444-grw5s2pf	1547	39	particle	particle	NN
cord-256444-grw5s2pf	1547	40	types	type	NNS
cord-256444-grw5s2pf	1547	41	of	of	IN
cord-256444-grw5s2pf	1547	42	avian	avian	JJ
cord-256444-grw5s2pf	1547	43	infectious	infectious	JJ
cord-256444-grw5s2pf	1547	44	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1547	45	virus	virus	NN
cord-256444-grw5s2pf	1547	46	Ribonucleoprotein	ribonucleoprotein	NN
cord-256444-grw5s2pf	1547	47	-	-	HYPH
cord-256444-grw5s2pf	1547	48	like	like	JJ
cord-256444-grw5s2pf	1547	49	structures	structure	NNS
cord-256444-grw5s2pf	1547	50	from	from	IN
cord-256444-grw5s2pf	1547	51	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1547	52	particles	particle	NNS
cord-256444-grw5s2pf	1547	53	RNA	rna	NN
cord-256444-grw5s2pf	1547	54	-	-	HYPH
cord-256444-grw5s2pf	1547	55	dependent	dependent	JJ
cord-256444-grw5s2pf	1547	56	RNA	RNA	NNP
cord-256444-grw5s2pf	1547	57	polymerase	polymerase	NN
cord-256444-grw5s2pf	1547	58	activity	activity	NN
cord-256444-grw5s2pf	1547	59	in	in	IN
cord-256444-grw5s2pf	1547	60	murine	murine	JJ
cord-256444-grw5s2pf	1547	61	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1547	62	-	-	HYPH
cord-256444-grw5s2pf	1547	63	infected	infect	VBN
cord-256444-grw5s2pf	1547	64	cells	cell	NNS
cord-256444-grw5s2pf	1548	1	Effect	effect	NN
cord-256444-grw5s2pf	1548	2	ofintergenic	ofintergenic	NNP
cord-256444-grw5s2pf	1548	3	consensus	consensus	NN
cord-256444-grw5s2pf	1548	4	sequence	sequence	NN
cord-256444-grw5s2pf	1548	5	flanking	flank	VBG
cord-256444-grw5s2pf	1548	6	sequences	sequence	NNS
cord-256444-grw5s2pf	1548	7	on	on	IN
cord-256444-grw5s2pf	1548	8	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1548	9	transcription	transcription	NN
cord-256444-grw5s2pf	1548	10	Evolution	evolution	NN
cord-256444-grw5s2pf	1548	11	of	of	IN
cord-256444-grw5s2pf	1548	12	the	the	DT
cord-256444-grw5s2pf	1548	13	5'-end	5'-end	CD
cord-256444-grw5s2pf	1548	14	of	of	IN
cord-256444-grw5s2pf	1548	15	genomic	genomic	JJ
cord-256444-grw5s2pf	1548	16	RNA	RNA	NNP
cord-256444-grw5s2pf	1548	17	of	of	IN
cord-256444-grw5s2pf	1548	18	murine	murine	JJ
cord-256444-grw5s2pf	1548	19	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1548	20	during	during	IN
cord-256444-grw5s2pf	1548	21	passages	passage	NNS
cord-256444-grw5s2pf	1548	22	in	in	IN
cord-256444-grw5s2pf	1548	23	vitro	vitro	FW
cord-256444-grw5s2pf	1548	24	High	high	JJ
cord-256444-grw5s2pf	1548	25	-	-	HYPH
cord-256444-grw5s2pf	1548	26	frequency	frequency	NN
cord-256444-grw5s2pf	1548	27	leader	leader	NN
cord-256444-grw5s2pf	1548	28	sequence	sequence	NN
cord-256444-grw5s2pf	1548	29	switching	switch	VBG
cord-256444-grw5s2pf	1548	30	during	during	IN
cord-256444-grw5s2pf	1548	31	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1548	32	defective	defective	JJ
cord-256444-grw5s2pf	1548	33	interfering	interfere	VBG
cord-256444-grw5s2pf	1548	34	RNA	RNA	NNP
cord-256444-grw5s2pf	1548	35	replication	replication	NN
cord-256444-grw5s2pf	1548	36	Structure	structure	NN
cord-256444-grw5s2pf	1548	37	of	of	IN
cord-256444-grw5s2pf	1548	38	the	the	DT
cord-256444-grw5s2pf	1548	39	intracellular	intracellular	JJ
cord-256444-grw5s2pf	1548	40	defective	defective	JJ
cord-256444-grw5s2pf	1548	41	viral	viral	JJ
cord-256444-grw5s2pf	1548	42	RNAs	rna	NNS
cord-256444-grw5s2pf	1548	43	of	of	IN
cord-256444-grw5s2pf	1548	44	defective	defective	JJ
cord-256444-grw5s2pf	1548	45	interfering	interfere	VBG
cord-256444-grw5s2pf	1548	46	particles	particle	NNS
cord-256444-grw5s2pf	1548	47	of	of	IN
cord-256444-grw5s2pf	1548	48	mouse	mouse	NN
cord-256444-grw5s2pf	1548	49	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1548	50	virus	virus	NN
cord-256444-grw5s2pf	1548	51	High	high	JJ
cord-256444-grw5s2pf	1548	52	-	-	HYPH
cord-256444-grw5s2pf	1548	53	frequency	frequency	NN
cord-256444-grw5s2pf	1548	54	RNA	RNA	NNP
cord-256444-grw5s2pf	1548	55	recombination	recombination	NN
cord-256444-grw5s2pf	1548	56	of	of	IN
cord-256444-grw5s2pf	1548	57	murine	murine	JJ
cord-256444-grw5s2pf	1548	58	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1548	59	Leader	Leader	NNP
cord-256444-grw5s2pf	1548	60	sequences	sequence	NNS
cord-256444-grw5s2pf	1548	61	of	of	IN
cord-256444-grw5s2pf	1548	62	murine	murine	JJ
cord-256444-grw5s2pf	1548	63	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1548	64	mRNAs	mrnas	WDT
cord-256444-grw5s2pf	1548	65	can	can	MD
cord-256444-grw5s2pf	1548	66	be	be	VB
cord-256444-grw5s2pf	1548	67	freely	freely	RB
cord-256444-grw5s2pf	1548	68	reassorted	reassorte	VBN
cord-256444-grw5s2pf	1549	1	:	:	:
cord-256444-grw5s2pf	1549	2	Evidence	evidence	NN
cord-256444-grw5s2pf	1549	3	for	for	IN
cord-256444-grw5s2pf	1549	4	the	the	DT
cord-256444-grw5s2pf	1549	5	role	role	NN
cord-256444-grw5s2pf	1549	6	of	of	IN
cord-256444-grw5s2pf	1549	7	free	free	JJ
cord-256444-grw5s2pf	1549	8	leader	leader	NN
cord-256444-grw5s2pf	1549	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1549	10	in	in	IN
cord-256444-grw5s2pf	1549	11	transcription	transcription	NN
cord-256444-grw5s2pf	1549	12	RNA	RNA	NNP
cord-256444-grw5s2pf	1549	13	recombination	recombination	NN
cord-256444-grw5s2pf	1549	14	of	of	IN
cord-256444-grw5s2pf	1549	15	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1549	16	:	:	:
cord-256444-grw5s2pf	1550	1	Localization	localization	NN
cord-256444-grw5s2pf	1550	2	of	of	IN
cord-256444-grw5s2pf	1550	3	neutralizing	neutralize	VBG
cord-256444-grw5s2pf	1550	4	epitopes	epitope	NNS
cord-256444-grw5s2pf	1550	5	and	and	CC
cord-256444-grw5s2pf	1550	6	neuropathogenic	neuropathogenic	JJ
cord-256444-grw5s2pf	1550	7	determinants	determinant	NNS
cord-256444-grw5s2pf	1550	8	on	on	IN
cord-256444-grw5s2pf	1550	9	the	the	DT
cord-256444-grw5s2pf	1550	10	carboxyl	carboxyl	NN
cord-256444-grw5s2pf	1550	11	terminus	terminus	NN
cord-256444-grw5s2pf	1550	12	of	of	IN
cord-256444-grw5s2pf	1550	13	peplomers	peplomer	NNS
cord-256444-grw5s2pf	1550	14	Defective	Defective	NNP
cord-256444-grw5s2pf	1550	15	interfering	interfere	VBG
cord-256444-grw5s2pf	1550	16	particles	particle	NNS
cord-256444-grw5s2pf	1550	17	of	of	IN
cord-256444-grw5s2pf	1550	18	murine	murine	JJ
cord-256444-grw5s2pf	1550	19	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1550	20	:	:	:
cord-256444-grw5s2pf	1550	21	Mechanism	mechanism	NN
cord-256444-grw5s2pf	1550	22	of	of	IN
cord-256444-grw5s2pf	1550	23	synthesis	synthesis	NN
cord-256444-grw5s2pf	1550	24	of	of	IN
cord-256444-grw5s2pf	1550	25	defective	defective	JJ
cord-256444-grw5s2pf	1550	26	viral	viral	JJ
cord-256444-grw5s2pf	1550	27	RNAs	rna	NNS
cord-256444-grw5s2pf	1550	28	Primary	primary	JJ
cord-256444-grw5s2pf	1550	29	structure	structure	NN
cord-256444-grw5s2pf	1550	30	and	and	CC
cord-256444-grw5s2pf	1550	31	translation	translation	NN
cord-256444-grw5s2pf	1550	32	of	of	IN
cord-256444-grw5s2pf	1550	33	a	a	DT
cord-256444-grw5s2pf	1550	34	defective	defective	JJ
cord-256444-grw5s2pf	1550	35	-	-	HYPH
cord-256444-grw5s2pf	1550	36	interfering	interfere	VBG
cord-256444-grw5s2pf	1550	37	RNA	RNA	NNP
cord-256444-grw5s2pf	1550	38	of	of	IN
cord-256444-grw5s2pf	1550	39	murine	murine	JJ
cord-256444-grw5s2pf	1550	40	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1550	41	Discontinuous	discontinuous	JJ
cord-256444-grw5s2pf	1550	42	transcription	transcription	NN
cord-256444-grw5s2pf	1550	43	generates	generate	VBZ
cord-256444-grw5s2pf	1550	44	heterogeneity	heterogeneity	NN
cord-256444-grw5s2pf	1550	45	a	a	DT
cord-256444-grw5s2pf	1550	46	t	t	NN
cord-256444-grw5s2pf	1550	47	the	the	DT
cord-256444-grw5s2pf	1550	48	leader	leader	NN
cord-256444-grw5s2pf	1550	49	fusion	fusion	NN
cord-256444-grw5s2pf	1550	50	sites	site	NNS
cord-256444-grw5s2pf	1550	51	of	of	IN
cord-256444-grw5s2pf	1550	52	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1550	53	mRNAs	mrnas	ADD
cord-256444-grw5s2pf	1550	54	Analysis	Analysis	NNP
cord-256444-grw5s2pf	1550	55	of	of	IN
cord-256444-grw5s2pf	1550	56	efficiently	efficiently	RB
cord-256444-grw5s2pf	1550	57	packaged	package	VBN
cord-256444-grw5s2pf	1550	58	defective	defective	JJ
cord-256444-grw5s2pf	1550	59	-	-	HYPH
cord-256444-grw5s2pf	1550	60	interfering	interfere	VBG
cord-256444-grw5s2pf	1550	61	RNAs	rna	NNS
cord-256444-grw5s2pf	1550	62	of	of	IN
cord-256444-grw5s2pf	1550	63	murine	murine	JJ
cord-256444-grw5s2pf	1550	64	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1550	65	:	:	:
cord-256444-grw5s2pf	1550	66	Localization	localization	NN
cord-256444-grw5s2pf	1550	67	of	of	IN
cord-256444-grw5s2pf	1550	68	a	a	DT
cord-256444-grw5s2pf	1550	69	possible	possible	JJ
cord-256444-grw5s2pf	1550	70	RNApackaging	rnapackaging	NN
cord-256444-grw5s2pf	1550	71	signal	signal	VB
cord-256444-grw5s2pf	1550	72	A	a	DT
cord-256444-grw5s2pf	1550	73	system	system	NN
cord-256444-grw5s2pf	1550	74	for	for	IN
cord-256444-grw5s2pf	1550	75	study	study	NN
cord-256444-grw5s2pf	1550	76	of	of	IN
cord-256444-grw5s2pf	1550	77	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1550	78	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1550	79	synthesis	synthesis	NN
cord-256444-grw5s2pf	1550	80	:	:	:
cord-256444-grw5s2pf	1551	1	A	a	DT
cord-256444-grw5s2pf	1551	2	regulated	regulate	VBN
cord-256444-grw5s2pf	1551	3	,	,	,
cord-256444-grw5s2pf	1551	4	expressed	express	VBD
cord-256444-grw5s2pf	1551	5	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1551	6	defective	defective	NNP
cord-256444-grw5s2pf	1551	7	-	-	HYPH
cord-256444-grw5s2pf	1551	8	interfering	interfere	VBG
cord-256444-grw5s2pf	1551	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1551	10	results	result	NNS
cord-256444-grw5s2pf	1551	11	from	from	IN
cord-256444-grw5s2pf	1551	12	intergenic	intergenic	JJ
cord-256444-grw5s2pf	1551	13	site	site	NN
cord-256444-grw5s2pf	1551	14	insertion	insertion	NN
cord-256444-grw5s2pf	1551	15	Localization	Localization	NNP
cord-256444-grw5s2pf	1551	16	of	of	IN
cord-256444-grw5s2pf	1551	17	an	an	DT
cord-256444-grw5s2pf	1551	18	RNA	rna	NN
cord-256444-grw5s2pf	1551	19	-	-	HYPH
cord-256444-grw5s2pf	1551	20	binding	bind	VBG
cord-256444-grw5s2pf	1551	21	domain	domain	NN
cord-256444-grw5s2pf	1551	22	in	in	IN
cord-256444-grw5s2pf	1551	23	the	the	DT
cord-256444-grw5s2pf	1551	24	nucleocapsid	nucleocapsid	NNP
cord-256444-grw5s2pf	1551	25	protein	protein	NN
cord-256444-grw5s2pf	1551	26	of	of	IN
cord-256444-grw5s2pf	1551	27	the	the	DT
cord-256444-grw5s2pf	1551	28	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1551	29	mouse	mouse	NN
cord-256444-grw5s2pf	1551	30	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1551	31	virus	virus	NN
cord-256444-grw5s2pf	1551	32	Optimization	Optimization	NNP
cord-256444-grw5s2pf	1551	33	of	of	IN
cord-256444-grw5s2pf	1551	34	targeted	target	VBN
cord-256444-grw5s2pf	1551	35	RNA	RNA	NNP
cord-256444-grw5s2pf	1551	36	recombination	recombination	NN
cord-256444-grw5s2pf	1551	37	and	and	CC
cord-256444-grw5s2pf	1551	38	mapping	mapping	NN
cord-256444-grw5s2pf	1551	39	of	of	IN
cord-256444-grw5s2pf	1551	40	a	a	DT
cord-256444-grw5s2pf	1551	41	novel	novel	JJ
cord-256444-grw5s2pf	1551	42	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1551	43	gene	gene	NN
cord-256444-grw5s2pf	1551	44	mutation	mutation	NN
cord-256444-grw5s2pf	1551	45	in	in	IN
cord-256444-grw5s2pf	1551	46	the	the	DT
cord-256444-grw5s2pf	1551	47	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1551	48	mouse	mouse	NN
cord-256444-grw5s2pf	1551	49	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1551	50	virus	virus	NN
cord-256444-grw5s2pf	1551	51	Membrane	Membrane	NNP
cord-256444-grw5s2pf	1551	52	integration	integration	NN
cord-256444-grw5s2pf	1551	53	and	and	CC
cord-256444-grw5s2pf	1551	54	intracellular	intracellular	JJ
cord-256444-grw5s2pf	1551	55	transport	transport	NN
cord-256444-grw5s2pf	1551	56	of	of	IN
cord-256444-grw5s2pf	1551	57	the	the	DT
cord-256444-grw5s2pf	1551	58	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1551	59	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1551	60	E	E	NNP
cord-256444-grw5s2pf	1551	61	l	l	NN
cord-256444-grw5s2pf	1551	62	,	,	,
cord-256444-grw5s2pf	1551	63	a	a	DT
cord-256444-grw5s2pf	1551	64	class	class	NN
cord-256444-grw5s2pf	1551	65	I11	I11	NNP
cord-256444-grw5s2pf	1551	66	membrane	membrane	NN
cord-256444-grw5s2pf	1551	67	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1551	68	Molecular	molecular	JJ
cord-256444-grw5s2pf	1551	69	characterization	characterization	NN
cord-256444-grw5s2pf	1551	70	of	of	IN
cord-256444-grw5s2pf	1551	71	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1551	72	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1551	73	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1551	74	defective	defective	JJ
cord-256444-grw5s2pf	1551	75	interfering	interfere	VBG
cord-256444-grw5s2pf	1551	76	genomes	genome	NNS
cord-256444-grw5s2pf	1551	77	:	:	:
cord-256444-grw5s2pf	1552	1	Packaging	packaging	NN
cord-256444-grw5s2pf	1552	2	and	and	CC
cord-256444-grw5s2pf	1552	3	heterogeneity	heterogeneity	NN
cord-256444-grw5s2pf	1552	4	Attenuation	attenuation	NN
cord-256444-grw5s2pf	1552	5	ofmurine	ofmurine	NN
cord-256444-grw5s2pf	1552	6	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1552	7	infection	infection	NN
cord-256444-grw5s2pf	1552	8	by	by	IN
cord-256444-grw5s2pf	1552	9	ammonium	ammonium	NN
cord-256444-grw5s2pf	1552	10	chloride	chloride	NN
cord-256444-grw5s2pf	1552	11	Endosomal	Endosomal	NNP
cord-256444-grw5s2pf	1552	12	association	association	NN
cord-256444-grw5s2pf	1552	13	of	of	IN
cord-256444-grw5s2pf	1552	14	a	a	DT
cord-256444-grw5s2pf	1552	15	protein	protein	NN
cord-256444-grw5s2pf	1552	16	phosphatase	phosphatase	NN
cord-256444-grw5s2pf	1552	17	with	with	IN
cord-256444-grw5s2pf	1552	18	high	high	JJ
cord-256444-grw5s2pf	1552	19	dephosphorylating	dephosphorylating	NN
cord-256444-grw5s2pf	1552	20	activity	activity	NN
cord-256444-grw5s2pf	1552	21	against	against	IN
cord-256444-grw5s2pf	1552	22	a	a	DT
cord-256444-grw5s2pf	1552	23	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1552	24	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1552	25	protein	protein	NN
cord-256444-grw5s2pf	1552	26	Human	Human	NNP
cord-256444-grw5s2pf	1552	27	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1552	28	OC43	OC43	NNP
cord-256444-grw5s2pf	1552	29	RNA	RNA	NNP
cord-256444-grw5s2pf	1552	30	4	4	CD
cord-256444-grw5s2pf	1552	31	lacks	lack	VBZ
cord-256444-grw5s2pf	1552	32	two	two	CD
cord-256444-grw5s2pf	1552	33	open	open	JJ
cord-256444-grw5s2pf	1552	34	reading	reading	NN
cord-256444-grw5s2pf	1552	35	frames	frame	NNS
cord-256444-grw5s2pf	1552	36	located	locate	VBN
cord-256444-grw5s2pf	1552	37	downstream	downstream	RB
cord-256444-grw5s2pf	1552	38	of	of	IN
cord-256444-grw5s2pf	1552	39	the	the	DT
cord-256444-grw5s2pf	1552	40	S	S	NNP
cord-256444-grw5s2pf	1552	41	gene	gene	NN
cord-256444-grw5s2pf	1552	42	of	of	IN
cord-256444-grw5s2pf	1552	43	bovine	bovine	JJ
cord-256444-grw5s2pf	1552	44	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1552	45	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1552	46	infects	infect	VBZ
cord-256444-grw5s2pf	1552	47	and	and	CC
cord-256444-grw5s2pf	1552	48	causes	cause	VBZ
cord-256444-grw5s2pf	1552	49	demyelination	demyelination	NN
cord-256444-grw5s2pf	1552	50	in	in	IN
cord-256444-grw5s2pf	1552	51	primate	primate	JJ
cord-256444-grw5s2pf	1552	52	central	central	JJ
cord-256444-grw5s2pf	1552	53	nervous	nervous	JJ
cord-256444-grw5s2pf	1552	54	system	system	NN
cord-256444-grw5s2pf	1552	55	Influenza	Influenza	NNP
cord-256444-grw5s2pf	1552	56	C	C	NNP
cord-256444-grw5s2pf	1552	57	virus	virus	NN
cord-256444-grw5s2pf	1552	58	hemagglutinin	hemagglutinin	NN
cord-256444-grw5s2pf	1552	59	:	:	:
cord-256444-grw5s2pf	1552	60	Comparison	comparison	NN
cord-256444-grw5s2pf	1552	61	with	with	IN
cord-256444-grw5s2pf	1552	62	influenza	influenza	NN
cord-256444-grw5s2pf	1552	63	A	a	NN
cord-256444-grw5s2pf	1552	64	and	and	CC
cord-256444-grw5s2pf	1552	65	B	B	NNP
cord-256444-grw5s2pf	1552	66	virus	virus	NN
cord-256444-grw5s2pf	1552	67	hemagglutinins	hemagglutinins	NNP
cord-256444-grw5s2pf	1552	68	Bgp2	Bgp2	NNP
cord-256444-grw5s2pf	1552	69	,	,	,
cord-256444-grw5s2pf	1552	70	a	a	DT
cord-256444-grw5s2pf	1552	71	new	new	JJ
cord-256444-grw5s2pf	1552	72	member	member	NN
cord-256444-grw5s2pf	1552	73	of	of	IN
cord-256444-grw5s2pf	1552	74	the	the	DT
cord-256444-grw5s2pf	1552	75	carcinoembryonic	carcinoembryonic	NNP
cord-256444-grw5s2pf	1552	76	antigen	antigen	NN
cord-256444-grw5s2pf	1552	77	-	-	HYPH
cord-256444-grw5s2pf	1552	78	related	relate	VBN
cord-256444-grw5s2pf	1552	79	gene	gene	NN
cord-256444-grw5s2pf	1552	80	family	family	NN
cord-256444-grw5s2pf	1552	81	,	,	,
cord-256444-grw5s2pf	1552	82	encodes	encode	VBZ
cord-256444-grw5s2pf	1552	83	an	an	DT
cord-256444-grw5s2pf	1552	84	alternative	alternative	JJ
cord-256444-grw5s2pf	1552	85	receptor	receptor	NN
cord-256444-grw5s2pf	1552	86	for	for	IN
cord-256444-grw5s2pf	1552	87	mouse	mouse	NN
cord-256444-grw5s2pf	1552	88	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1552	89	virus	virus	NN
cord-256444-grw5s2pf	1552	90	Localization	Localization	NNP
cord-256444-grw5s2pf	1552	91	of	of	IN
cord-256444-grw5s2pf	1552	92	the	the	DT
cord-256444-grw5s2pf	1552	93	RNA	RNA	NNP
cord-256444-grw5s2pf	1552	94	-	-	HYPH
cord-256444-grw5s2pf	1552	95	binding	bind	VBG
cord-256444-grw5s2pf	1552	96	domain	domain	NN
cord-256444-grw5s2pf	1552	97	of	of	IN
cord-256444-grw5s2pf	1552	98	MHV	MHV	NNP
cord-256444-grw5s2pf	1552	99	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1552	100	protein	protein	NN
cord-256444-grw5s2pf	1552	101	Post	post	JJ
cord-256444-grw5s2pf	1552	102	-	-	JJ
cord-256444-grw5s2pf	1552	103	translational	translational	JJ
cord-256444-grw5s2pf	1552	104	glycosylation	glycosylation	NN
cord-256444-grw5s2pf	1552	105	of	of	IN
cord-256444-grw5s2pf	1552	106	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1552	107	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1552	108	El	El	NNP
cord-256444-grw5s2pf	1552	109	:	:	:
cord-256444-grw5s2pf	1553	1	Inhibition	inhibition	NN
cord-256444-grw5s2pf	1553	2	by	by	IN
cord-256444-grw5s2pf	1553	3	monensin	monensin	NNP
cord-256444-grw5s2pf	1554	1	The	the	DT
cord-256444-grw5s2pf	1554	2	carbohydrates	carbohydrate	NNS
cord-256444-grw5s2pf	1554	3	of	of	IN
cord-256444-grw5s2pf	1555	1	mouse	mouse	NNP
cord-256444-grw5s2pf	1555	2	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1555	3	virus	virus	NN
cord-256444-grw5s2pf	1555	4	(	(	-LRB-
cord-256444-grw5s2pf	1555	5	MHV	MHV	NNP
cord-256444-grw5s2pf	1555	6	)	)	-RRB-
cord-256444-grw5s2pf	1555	7	A59	A59	NNP
cord-256444-grw5s2pf	1555	8	:	:	:
cord-256444-grw5s2pf	1556	1	Structures	structure	NNS
cord-256444-grw5s2pf	1556	2	of	of	IN
cord-256444-grw5s2pf	1556	3	the	the	DT
cord-256444-grw5s2pf	1556	4	0-glycosidically	0-glycosidically	CD
cord-256444-grw5s2pf	1556	5	linked	link	VBN
cord-256444-grw5s2pf	1556	6	oligosaccharides	oligosaccharide	NNS
cord-256444-grw5s2pf	1556	7	of	of	IN
cord-256444-grw5s2pf	1556	8	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1556	9	El	El	NNP
cord-256444-grw5s2pf	1557	1	The	the	DT
cord-256444-grw5s2pf	1557	2	encephalomyocarditis	encephalomyocarditis	NNP
cord-256444-grw5s2pf	1557	3	virus	virus	NN
cord-256444-grw5s2pf	1557	4	3C	3c	NN
cord-256444-grw5s2pf	1557	5	protease	protease	NN
cord-256444-grw5s2pf	1557	6	is	be	VBZ
cord-256444-grw5s2pf	1557	7	rapidly	rapidly	RB
cord-256444-grw5s2pf	1557	8	degraded	degrade	VBN
cord-256444-grw5s2pf	1557	9	by	by	IN
cord-256444-grw5s2pf	1557	10	an	an	DT
cord-256444-grw5s2pf	1557	11	ATP	ATP	NNP
cord-256444-grw5s2pf	1557	12	-	-	HYPH
cord-256444-grw5s2pf	1557	13	dependent	dependent	JJ
cord-256444-grw5s2pf	1557	14	proteolytic	proteolytic	JJ
cord-256444-grw5s2pf	1557	15	system	system	NN
cord-256444-grw5s2pf	1557	16	in	in	IN
cord-256444-grw5s2pf	1557	17	reticulocyte	reticulocyte	NN
cord-256444-grw5s2pf	1557	18	lysate	lysate	NN
cord-256444-grw5s2pf	1557	19	Immunoglobulin	Immunoglobulin	NNP
cord-256444-grw5s2pf	1557	20	Fc	Fc	NNP
cord-256444-grw5s2pf	1557	21	binding	bind	VBG
cord-256444-grw5s2pf	1557	22	activity	activity	NN
cord-256444-grw5s2pf	1557	23	is	be	VBZ
cord-256444-grw5s2pf	1557	24	associated	associate	VBN
cord-256444-grw5s2pf	1557	25	with	with	IN
cord-256444-grw5s2pf	1557	26	the	the	DT
cord-256444-grw5s2pf	1557	27	mouse	mouse	NN
cord-256444-grw5s2pf	1557	28	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1557	29	virus	virus	NN
cord-256444-grw5s2pf	1557	30	E2	E2	NNP
cord-256444-grw5s2pf	1557	31	peplomer	peplomer	NNP
cord-256444-grw5s2pf	1558	1	protein	protein	NN
cord-256444-grw5s2pf	1558	2	MHV	MHV	NNP
cord-256444-grw5s2pf	1558	3	S	S	NNP
cord-256444-grw5s2pf	1558	4	peplomer	peplomer	NN
cord-256444-grw5s2pf	1558	5	protein	protein	NN
cord-256444-grw5s2pf	1558	6	expressed	express	VBN
cord-256444-grw5s2pf	1558	7	by	by	IN
cord-256444-grw5s2pf	1558	8	a	a	DT
cord-256444-grw5s2pf	1558	9	recombinant	recombinant	JJ
cord-256444-grw5s2pf	1558	10	vaccinia	vaccinia	NN
cord-256444-grw5s2pf	1558	11	virus	virus	NN
cord-256444-grw5s2pf	1558	12	vector	vector	NN
cord-256444-grw5s2pf	1558	13	exhibits	exhibit	VBZ
cord-256444-grw5s2pf	1558	14	IgG	IgG	NNP
cord-256444-grw5s2pf	1558	15	Fc	Fc	NNP
cord-256444-grw5s2pf	1558	16	-	-	HYPH
cord-256444-grw5s2pf	1558	17	receptor	receptor	NN
cord-256444-grw5s2pf	1558	18	activity	activity	NN
cord-256444-grw5s2pf	1558	19	Molecular	molecular	JJ
cord-256444-grw5s2pf	1558	20	mimicry	mimicry	NN
cord-256444-grw5s2pf	1558	21	between	between	IN
cord-256444-grw5s2pf	1558	22	Fc	Fc	NNP
cord-256444-grw5s2pf	1558	23	receptor	receptor	NN
cord-256444-grw5s2pf	1558	24	and	and	CC
cord-256444-grw5s2pf	1558	25	S	S	NNP
cord-256444-grw5s2pf	1558	26	peplomer	peplomer	NNP
cord-256444-grw5s2pf	1558	27	protein	protein	NN
cord-256444-grw5s2pf	1558	28	of	of	IN
cord-256444-grw5s2pf	1558	29	mouse	mouse	NNP
cord-256444-grw5s2pf	1558	30	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1558	31	virus	virus	NN
cord-256444-grw5s2pf	1558	32	,	,	,
cord-256444-grw5s2pf	1558	33	bovine	bovine	JJ
cord-256444-grw5s2pf	1558	34	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1558	35	,	,	,
cord-256444-grw5s2pf	1558	36	and	and	CC
cord-256444-grw5s2pf	1558	37	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1558	38	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1558	39	virus	virus	NN
cord-256444-grw5s2pf	1558	40	Monoclonal	monoclonal	JJ
cord-256444-grw5s2pf	1558	41	antibodies	antibody	NNS
cord-256444-grw5s2pf	1558	42	to	to	IN
cord-256444-grw5s2pf	1558	43	the	the	DT
cord-256444-grw5s2pf	1558	44	spike	spike	NN
cord-256444-grw5s2pf	1558	45	protein	protein	NN
cord-256444-grw5s2pf	1558	46	of	of	IN
cord-256444-grw5s2pf	1558	47	feline	feline	JJ
cord-256444-grw5s2pf	1558	48	infectious	infectious	JJ
cord-256444-grw5s2pf	1558	49	peritonitis	peritonitis	NN
cord-256444-grw5s2pf	1558	50	virus	virus	NN
cord-256444-grw5s2pf	1558	51	mediate	mediate	VB
cord-256444-grw5s2pf	1558	52	antibody	antibody	NN
cord-256444-grw5s2pf	1558	53	-	-	HYPH
cord-256444-grw5s2pf	1558	54	dependent	dependent	JJ
cord-256444-grw5s2pf	1558	55	enhancement	enhancement	NN
cord-256444-grw5s2pf	1558	56	of	of	IN
cord-256444-grw5s2pf	1558	57	infection	infection	NN
cord-256444-grw5s2pf	1558	58	of	of	IN
cord-256444-grw5s2pf	1558	59	feline	feline	JJ
cord-256444-grw5s2pf	1558	60	macrophages	macrophage	NNS
cord-256444-grw5s2pf	1558	61	Disulfide	Disulfide	NNP
cord-256444-grw5s2pf	1558	62	bonds	bond	NNS
cord-256444-grw5s2pf	1558	63	in	in	IN
cord-256444-grw5s2pf	1558	64	folding	folding	NN
cord-256444-grw5s2pf	1558	65	and	and	CC
cord-256444-grw5s2pf	1558	66	transport	transport	NN
cord-256444-grw5s2pf	1558	67	of	of	IN
cord-256444-grw5s2pf	1558	68	mouse	mouse	NN
cord-256444-grw5s2pf	1558	69	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1558	70	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1558	71	glycoproteins	glycoprotein	NNS
cord-256444-grw5s2pf	1558	72	Envelope	Envelope	NNP
cord-256444-grw5s2pf	1558	73	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1558	74	interactions	interaction	NNS
cord-256444-grw5s2pf	1558	75	in	in	IN
cord-256444-grw5s2pf	1558	76	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1558	77	assembly	assembly	NN
cord-256444-grw5s2pf	1558	78	Cloning	cloning	NN
cord-256444-grw5s2pf	1558	79	and	and	CC
cord-256444-grw5s2pf	1558	80	in	in	IN
cord-256444-grw5s2pf	1558	81	vitro	vitro	FW
cord-256444-grw5s2pf	1558	82	expression	expression	NN
cord-256444-grw5s2pf	1558	83	of	of	IN
cord-256444-grw5s2pf	1558	84	the	the	DT
cord-256444-grw5s2pf	1558	85	gene	gene	NN
cord-256444-grw5s2pf	1558	86	for	for	IN
cord-256444-grw5s2pf	1558	87	the	the	DT
cord-256444-grw5s2pf	1558	88	E3	E3	NNP
cord-256444-grw5s2pf	1558	89	haemagglutinin	haemagglutinin	NN
cord-256444-grw5s2pf	1558	90	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1558	91	of	of	IN
cord-256444-grw5s2pf	1558	92	bovine	bovine	JJ
cord-256444-grw5s2pf	1558	93	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1558	94	Expression	expression	NN
cord-256444-grw5s2pf	1558	95	and	and	CC
cord-256444-grw5s2pf	1558	96	secretion	secretion	NN
cord-256444-grw5s2pf	1558	97	of	of	IN
cord-256444-grw5s2pf	1558	98	the	the	DT
cord-256444-grw5s2pf	1558	99	bovine	bovine	JJ
cord-256444-grw5s2pf	1558	100	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1558	101	hemagglutinin	hemagglutinin	NN
cord-256444-grw5s2pf	1558	102	-	-	HYPH
cord-256444-grw5s2pf	1558	103	esterase	esterase	NN
cord-256444-grw5s2pf	1558	104	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1558	105	by	by	IN
cord-256444-grw5s2pf	1558	106	insect	insect	NN
cord-256444-grw5s2pf	1558	107	cells	cell	NNS
cord-256444-grw5s2pf	1558	108	infected	infect	VBN
cord-256444-grw5s2pf	1558	109	with	with	IN
cord-256444-grw5s2pf	1558	110	recombinant	recombinant	JJ
cord-256444-grw5s2pf	1558	111	baculoviruses	baculoviruse	NNS
cord-256444-grw5s2pf	1558	112	Sequence	sequence	NN
cord-256444-grw5s2pf	1558	113	comparison	comparison	NN
cord-256444-grw5s2pf	1558	114	of	of	IN
cord-256444-grw5s2pf	1558	115	the	the	DT
cord-256444-grw5s2pf	1558	116	N	n	CD
cord-256444-grw5s2pf	1558	117	genes	gene	NNS
cord-256444-grw5s2pf	1558	118	of	of	IN
cord-256444-grw5s2pf	1558	119	five	five	CD
cord-256444-grw5s2pf	1558	120	strains	strain	NNS
cord-256444-grw5s2pf	1558	121	of	of	IN
cord-256444-grw5s2pf	1558	122	the	the	DT
cord-256444-grw5s2pf	1558	123	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1558	124	mouse	mouse	NN
cord-256444-grw5s2pf	1558	125	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1558	126	virus	virus	NN
cord-256444-grw5s2pf	1559	1	suggests	suggest	VBZ
cord-256444-grw5s2pf	1559	2	a	a	DT
cord-256444-grw5s2pf	1559	3	three	three	CD
cord-256444-grw5s2pf	1559	4	domain	domain	NN
cord-256444-grw5s2pf	1559	5	structure	structure	NN
cord-256444-grw5s2pf	1559	6	for	for	IN
cord-256444-grw5s2pf	1559	7	the	the	DT
cord-256444-grw5s2pf	1559	8	nucleocapsid	nucleocapsid	NNP
cord-256444-grw5s2pf	1559	9	protein	protein	NNP
cord-256444-grw5s2pf	1559	10	Sequence	Sequence	NNP
cord-256444-grw5s2pf	1559	11	analysis	analysis	NN
cord-256444-grw5s2pf	1559	12	reveals	reveal	VBZ
cord-256444-grw5s2pf	1559	13	extensive	extensive	JJ
cord-256444-grw5s2pf	1559	14	polymorphism	polymorphism	NN
cord-256444-grw5s2pf	1559	15	and	and	CC
cord-256444-grw5s2pf	1559	16	evidence	evidence	NN
cord-256444-grw5s2pf	1559	17	of	of	IN
cord-256444-grw5s2pf	1559	18	deletions	deletion	NNS
cord-256444-grw5s2pf	1559	19	within	within	IN
cord-256444-grw5s2pf	1559	20	the	the	DT
cord-256444-grw5s2pf	1559	21	E2	E2	NNP
cord-256444-grw5s2pf	1559	22	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1559	23	gene	gene	NN
cord-256444-grw5s2pf	1559	24	of	of	IN
cord-256444-grw5s2pf	1559	25	several	several	JJ
cord-256444-grw5s2pf	1559	26	strains	strain	NNS
cord-256444-grw5s2pf	1559	27	of	of	IN
cord-256444-grw5s2pf	1559	28	murine	murine	JJ
cord-256444-grw5s2pf	1559	29	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1559	30	virus	virus	NN
cord-256444-grw5s2pf	1559	31	Analysis	Analysis	NNP
cord-256444-grw5s2pf	1559	32	of	of	IN
cord-256444-grw5s2pf	1559	33	cell	cell	NN
cord-256444-grw5s2pf	1559	34	fusion	fusion	NN
cord-256444-grw5s2pf	1559	35	induced	induce	VBN
cord-256444-grw5s2pf	1559	36	by	by	IN
cord-256444-grw5s2pf	1559	37	bovine	bovine	JJ
cord-256444-grw5s2pf	1559	38	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1559	39	infection	infection	NN
cord-256444-grw5s2pf	1559	40	Analysis	analysis	NN
cord-256444-grw5s2pf	1559	41	of	of	IN
cord-256444-grw5s2pf	1559	42	second	second	JJ
cord-256444-grw5s2pf	1559	43	-	-	HYPH
cord-256444-grw5s2pf	1559	44	site	site	NN
cord-256444-grw5s2pf	1559	45	revertants	revertant	NNS
cord-256444-grw5s2pf	1559	46	of	of	IN
cord-256444-grw5s2pf	1559	47	a	a	DT
cord-256444-grw5s2pf	1559	48	murine	murine	JJ
cord-256444-grw5s2pf	1559	49	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1559	50	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1559	51	protein	protein	NN
cord-256444-grw5s2pf	1559	52	deletion	deletion	NN
cord-256444-grw5s2pf	1559	53	mutant	mutant	NN
cord-256444-grw5s2pf	1559	54	and	and	CC
cord-256444-grw5s2pf	1559	55	construction	construction	NN
cord-256444-grw5s2pf	1559	56	of	of	IN
cord-256444-grw5s2pf	1559	57	nucleocapsid	nucleocapsid	NNP
cord-256444-grw5s2pf	1559	58	protein	protein	NN
cord-256444-grw5s2pf	1559	59	mutants	mutant	NNS
cord-256444-grw5s2pf	1559	60	by	by	IN
cord-256444-grw5s2pf	1559	61	targeted	targeted	JJ
cord-256444-grw5s2pf	1559	62	RNArecombination	rnarecombination	NN
cord-256444-grw5s2pf	1559	63	Construction	construction	NN
cord-256444-grw5s2pf	1559	64	of	of	IN
cord-256444-grw5s2pf	1559	65	murine	murine	JJ
cord-256444-grw5s2pf	1559	66	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1559	67	mutants	mutant	NNS
cord-256444-grw5s2pf	1559	68	containing	contain	VBG
cord-256444-grw5s2pf	1559	69	interspecies	interspecie	NNS
cord-256444-grw5s2pf	1559	70	chimeric	chimeric	JJ
cord-256444-grw5s2pf	1559	71	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1559	72	proteins	protein	VBZ
cord-256444-grw5s2pf	1559	73	Isolation	isolation	NN
cord-256444-grw5s2pf	1559	74	of	of	IN
cord-256444-grw5s2pf	1559	75	a	a	DT
cord-256444-grw5s2pf	1559	76	porcine	porcine	JJ
cord-256444-grw5s2pf	1559	77	respiratory	respiratory	JJ
cord-256444-grw5s2pf	1559	78	,	,	,
cord-256444-grw5s2pf	1559	79	non	non	JJ
cord-256444-grw5s2pf	1559	80	-	-	JJ
cord-256444-grw5s2pf	1559	81	enteric	enteric	JJ
cord-256444-grw5s2pf	1559	82	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1559	83	related	relate	VBN
cord-256444-grw5s2pf	1559	84	to	to	IN
cord-256444-grw5s2pf	1559	85	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1559	86	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1559	87	Characterization	characterization	NN
cord-256444-grw5s2pf	1559	88	of	of	IN
cord-256444-grw5s2pf	1559	89	a	a	DT
cord-256444-grw5s2pf	1559	90	replicating	replicate	VBG
cord-256444-grw5s2pf	1559	91	and	and	CC
cord-256444-grw5s2pf	1559	92	packaged	package	VBN
cord-256444-grw5s2pf	1559	93	defective	defective	JJ
cord-256444-grw5s2pf	1559	94	RNA	RNA	NNP
cord-256444-grw5s2pf	1559	95	of	of	IN
cord-256444-grw5s2pf	1559	96	avian	avian	JJ
cord-256444-grw5s2pf	1559	97	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1559	98	infectious	infectious	JJ
cord-256444-grw5s2pf	1559	99	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1559	100	virus	virus	NN
cord-256444-grw5s2pf	1559	101	Replication	replication	NN
cord-256444-grw5s2pf	1559	102	and	and	CC
cord-256444-grw5s2pf	1559	103	packaging	packaging	NN
cord-256444-grw5s2pf	1559	104	of	of	IN
cord-256444-grw5s2pf	1559	105	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1559	106	infectious	infectious	JJ
cord-256444-grw5s2pf	1559	107	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1559	108	virus	virus	NN
cord-256444-grw5s2pf	1559	109	defective	defective	JJ
cord-256444-grw5s2pf	1559	110	RNAs	rna	NNS
cord-256444-grw5s2pf	1559	111	lacking	lack	VBG
cord-256444-grw5s2pf	1559	112	a	a	DT
cord-256444-grw5s2pf	1559	113	long	long	JJ
cord-256444-grw5s2pf	1559	114	open	open	JJ
cord-256444-grw5s2pf	1559	115	reading	reading	NN
cord-256444-grw5s2pf	1559	116	frame	frame	NN
cord-256444-grw5s2pf	1560	1	MHVnucleocapsid	mhvnucleocapsid	JJ
cord-256444-grw5s2pf	1560	2	synthesis	synthesis	NN
cord-256444-grw5s2pf	1560	3	in	in	IN
cord-256444-grw5s2pf	1560	4	the	the	DT
cord-256444-grw5s2pf	1560	5	presence	presence	NN
cord-256444-grw5s2pf	1560	6	of	of	IN
cord-256444-grw5s2pf	1560	7	cyclohexamide	cyclohexamide	NN
cord-256444-grw5s2pf	1560	8	and	and	CC
cord-256444-grw5s2pf	1560	9	accumulation	accumulation	NN
cord-256444-grw5s2pf	1560	10	of	of	IN
cord-256444-grw5s2pf	1560	11	negative	negative	JJ
cord-256444-grw5s2pf	1560	12	-	-	HYPH
cord-256444-grw5s2pf	1560	13	strand	strand	NN
cord-256444-grw5s2pf	1560	14	MHV	MHV	NNP
cord-256444-grw5s2pf	1560	15	RNA	RNA	NNP
cord-256444-grw5s2pf	1560	16	Functional	functional	JJ
cord-256444-grw5s2pf	1560	17	analysis	analysis	NN
cord-256444-grw5s2pf	1561	1	ofthe	ofthe	DT
cord-256444-grw5s2pf	1561	2	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1561	3	MHV	MHV	NNP
cord-256444-grw5s2pf	1561	4	-	-	HYPH
cord-256444-grw5s2pf	1561	5	JHM	JHM	NNP
cord-256444-grw5s2pf	1561	6	surface	surface	NN
cord-256444-grw5s2pf	1561	7	glycoproteins	glycoprotein	NNS
cord-256444-grw5s2pf	1561	8	in	in	IN
cord-256444-grw5s2pf	1561	9	vaccinia	vaccinia	NN
cord-256444-grw5s2pf	1561	10	virus	virus	NN
cord-256444-grw5s2pf	1561	11	recombinants	recombinant	NNS
cord-256444-grw5s2pf	1561	12	Lactate	Lactate	NNP
cord-256444-grw5s2pf	1561	13	dehydrogenase	dehydrogenase	NN
cord-256444-grw5s2pf	1561	14	-	-	HYPH
cord-256444-grw5s2pf	1561	15	elevating	elevate	VBG
cord-256444-grw5s2pf	1561	16	virus	virus	NN
cord-256444-grw5s2pf	1561	17	,	,	,
cord-256444-grw5s2pf	1561	18	equine	equine	JJ
cord-256444-grw5s2pf	1561	19	arteritis	arteritis	NN
cord-256444-grw5s2pf	1561	20	virus	virus	NN
cord-256444-grw5s2pf	1561	21	and	and	CC
cord-256444-grw5s2pf	1561	22	simian	simian	JJ
cord-256444-grw5s2pf	1561	23	haemorrhagic	haemorrhagic	JJ
cord-256444-grw5s2pf	1561	24	fever	fever	NN
cord-256444-grw5s2pf	1561	25	virus	virus	NN
cord-256444-grw5s2pf	1561	26	,	,	,
cord-256444-grw5s2pf	1561	27	a	a	DT
cord-256444-grw5s2pf	1561	28	new	new	JJ
cord-256444-grw5s2pf	1561	29	group	group	NN
cord-256444-grw5s2pf	1561	30	of	of	IN
cord-256444-grw5s2pf	1561	31	positive	positive	JJ
cord-256444-grw5s2pf	1561	32	strand	strand	NN
cord-256444-grw5s2pf	1561	33	RNA	RNA	NNP
cord-256444-grw5s2pf	1561	34	viruses	virus	NNS
cord-256444-grw5s2pf	1561	35	Porcine	porcine	JJ
cord-256444-grw5s2pf	1561	36	respiratory	respiratory	JJ
cord-256444-grw5s2pf	1561	37	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1561	38	differs	differ	VBZ
cord-256444-grw5s2pf	1561	39	from	from	IN
cord-256444-grw5s2pf	1561	40	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1561	41	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1561	42	virus	virus	NN
cord-256444-grw5s2pf	1561	43	by	by	IN
cord-256444-grw5s2pf	1561	44	a	a	DT
cord-256444-grw5s2pf	1561	45	few	few	JJ
cord-256444-grw5s2pf	1561	46	genomic	genomic	JJ
cord-256444-grw5s2pf	1561	47	deletions	deletion	NNS
cord-256444-grw5s2pf	1561	48	A	a	DT
cord-256444-grw5s2pf	1561	49	conditionallethal	conditionallethal	NN
cord-256444-grw5s2pf	1561	50	murine	murine	JJ
cord-256444-grw5s2pf	1561	51	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1561	52	mutant	mutant	NN
cord-256444-grw5s2pf	1561	53	that	that	WDT
cord-256444-grw5s2pf	1561	54	fails	fail	VBZ
cord-256444-grw5s2pf	1561	55	to	to	TO
cord-256444-grw5s2pf	1561	56	incorporate	incorporate	VB
cord-256444-grw5s2pf	1561	57	the	the	DT
cord-256444-grw5s2pf	1561	58	spike	spike	NN
cord-256444-grw5s2pf	1561	59	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1561	60	into	into	IN
cord-256444-grw5s2pf	1561	61	assembled	assemble	VBN
cord-256444-grw5s2pf	1561	62	virions	virion	NNS
cord-256444-grw5s2pf	1561	63	Membrane	membrane	NN
cord-256444-grw5s2pf	1561	64	protein	protein	NN
cord-256444-grw5s2pf	1561	65	molecules	molecule	NNS
cord-256444-grw5s2pf	1561	66	of	of	IN
cord-256444-grw5s2pf	1561	67	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1561	68	gastroenteritis	gastroenteritis	JJ
cord-256444-grw5s2pf	1561	69	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1561	70	also	also	RB
cord-256444-grw5s2pf	1561	71	expose	expose	VBP
cord-256444-grw5s2pf	1561	72	the	the	DT
cord-256444-grw5s2pf	1561	73	carboxy	carboxy	JJ
cord-256444-grw5s2pf	1561	74	-	-	HYPH
cord-256444-grw5s2pf	1561	75	terminal	terminal	NN
cord-256444-grw5s2pf	1561	76	region	region	NN
cord-256444-grw5s2pf	1561	77	on	on	IN
cord-256444-grw5s2pf	1561	78	the	the	DT
cord-256444-grw5s2pf	1561	79	external	external	JJ
cord-256444-grw5s2pf	1561	80	surface	surface	NN
cord-256444-grw5s2pf	1561	81	of	of	IN
cord-256444-grw5s2pf	1561	82	the	the	DT
cord-256444-grw5s2pf	1561	83	virion	virion	NN
cord-256444-grw5s2pf	1562	1	The	the	DT
cord-256444-grw5s2pf	1562	2	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1562	3	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1562	4	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1562	5	contains	contain	VBZ
cord-256444-grw5s2pf	1562	6	a	a	DT
cord-256444-grw5s2pf	1562	7	spherical	spherical	JJ
cord-256444-grw5s2pf	1562	8	core	core	NN
cord-256444-grw5s2pf	1562	9	shell	shell	NN
cord-256444-grw5s2pf	1562	10	consisting	consist	VBG
cord-256444-grw5s2pf	1562	11	of	of	IN
cord-256444-grw5s2pf	1562	12	M	M	NNP
cord-256444-grw5s2pf	1562	13	and	and	CC
cord-256444-grw5s2pf	1562	14	N	n	CD
cord-256444-grw5s2pf	1562	15	proteins	protein	NNS
cord-256444-grw5s2pf	1562	16	Pathogenic	pathogenic	JJ
cord-256444-grw5s2pf	1562	17	murine	murine	JJ
cord-256444-grw5s2pf	1562	18	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1562	19	.	.	.
cord-256444-grw5s2pf	1563	1	111	111	CD
cord-256444-grw5s2pf	1563	2	.	.	.
cord-256444-grw5s2pf	1564	1	Biological	biological	JJ
cord-256444-grw5s2pf	1564	2	and	and	CC
cord-256444-grw5s2pf	1564	3	biochemical	biochemical	JJ
cord-256444-grw5s2pf	1564	4	characterization	characterization	NN
cord-256444-grw5s2pf	1564	5	of	of	IN
cord-256444-grw5s2pf	1564	6	temperature	temperature	NN
cord-256444-grw5s2pf	1564	7	-	-	HYPH
cord-256444-grw5s2pf	1564	8	sensitive	sensitive	JJ
cord-256444-grw5s2pf	1564	9	mutants	mutant	NNS
cord-256444-grw5s2pf	1564	10	of	of	IN
cord-256444-grw5s2pf	1564	11	JHMV	JHMV	NNP
cord-256444-grw5s2pf	1564	12	RNA	RNA	NNP
cord-256444-grw5s2pf	1564	13	-	-	HYPH
cord-256444-grw5s2pf	1564	14	binding	bind	VBG
cord-256444-grw5s2pf	1564	15	proteins	protein	NNS
cord-256444-grw5s2pf	1564	16	of	of	IN
cord-256444-grw5s2pf	1564	17	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1564	18	MHV	mhv	NN
cord-256444-grw5s2pf	1564	19	:	:	:
cord-256444-grw5s2pf	1564	20	Detection	detection	NN
cord-256444-grw5s2pf	1564	21	of	of	IN
cord-256444-grw5s2pf	1564	22	monomeric	monomeric	JJ
cord-256444-grw5s2pf	1564	23	and	and	CC
cord-256444-grw5s2pf	1564	24	multimeric	multimeric	JJ
cord-256444-grw5s2pf	1564	25	N	n	CD
cord-256444-grw5s2pf	1564	26	protein	protein	NN
cord-256444-grw5s2pf	1564	27	with	with	IN
cord-256444-grw5s2pf	1564	28	an	an	DT
cord-256444-grw5s2pf	1564	29	RNA	RNA	NNP
cord-256444-grw5s2pf	1564	30	overlay	overlay	NN
cord-256444-grw5s2pf	1564	31	-	-	HYPH
cord-256444-grw5s2pf	1564	32	protein	protein	NN
cord-256444-grw5s2pf	1564	33	blot	blot	NN
cord-256444-grw5s2pf	1564	34	assay	assay	NN
cord-256444-grw5s2pf	1564	35	Entry	entry	NN
cord-256444-grw5s2pf	1564	36	and	and	CC
cord-256444-grw5s2pf	1564	37	release	release	NN
cord-256444-grw5s2pf	1564	38	of	of	IN
cord-256444-grw5s2pf	1564	39	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1564	40	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1564	41	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1564	42	are	be	VBP
cord-256444-grw5s2pf	1564	43	restricted	restrict	VBN
cord-256444-grw5s2pf	1564	44	to	to	IN
cord-256444-grw5s2pf	1564	45	apical	apical	JJ
cord-256444-grw5s2pf	1564	46	surfaces	surface	NNS
cord-256444-grw5s2pf	1564	47	of	of	IN
cord-256444-grw5s2pf	1564	48	polarized	polarized	JJ
cord-256444-grw5s2pf	1564	49	epithelial	epithelial	JJ
cord-256444-grw5s2pf	1564	50	cells	cell	NNS
cord-256444-grw5s2pf	1564	51	MHV	MHV	NNP
cord-256444-grw5s2pf	1564	52	-	-	HYPH
cord-256444-grw5s2pf	1564	53	A59	A59	NNP
cord-256444-grw5s2pf	1564	54	enters	enter	VBZ
cord-256444-grw5s2pf	1564	55	polarized	polarize	VBN
cord-256444-grw5s2pf	1564	56	murine	murine	JJ
cord-256444-grw5s2pf	1564	57	epithelial	epithelial	JJ
cord-256444-grw5s2pf	1564	58	cells	cell	NNS
cord-256444-grw5s2pf	1564	59	through	through	IN
cord-256444-grw5s2pf	1564	60	the	the	DT
cord-256444-grw5s2pf	1564	61	apical	apical	JJ
cord-256444-grw5s2pf	1564	62	surface	surface	NN
cord-256444-grw5s2pf	1564	63	but	but	CC
cord-256444-grw5s2pf	1564	64	is	be	VBZ
cord-256444-grw5s2pf	1564	65	released	release	VBN
cord-256444-grw5s2pf	1564	66	basolaterally	basolaterally	RB
cord-256444-grw5s2pf	1564	67	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1564	68	infection	infection	NN
cord-256444-grw5s2pf	1564	69	of	of	IN
cord-256444-grw5s2pf	1564	70	polarised	polarised	JJ
cord-256444-grw5s2pf	1564	71	epithelial	epithelial	JJ
cord-256444-grw5s2pf	1564	72	cells	cell	NNS
cord-256444-grw5s2pf	1565	1	Mouse	Mouse	NNP
cord-256444-grw5s2pf	1565	2	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1565	3	virus	virus	NN
cord-256444-grw5s2pf	1565	4	strain	strain	NN
cord-256444-grw5s2pf	1565	5	A59	A59	NNP
cord-256444-grw5s2pf	1565	6	is	be	VBZ
cord-256444-grw5s2pf	1565	7	released	release	VBN
cord-256444-grw5s2pf	1565	8	from	from	IN
cord-256444-grw5s2pf	1565	9	opposite	opposite	JJ
cord-256444-grw5s2pf	1565	10	sides	side	NNS
cord-256444-grw5s2pf	1565	11	of	of	IN
cord-256444-grw5s2pf	1565	12	different	different	JJ
cord-256444-grw5s2pf	1565	13	epithelial	epithelial	JJ
cord-256444-grw5s2pf	1565	14	cell	cell	NN
cord-256444-grw5s2pf	1565	15	types	type	NNS
cord-256444-grw5s2pf	1565	16	Assembly	Assembly	NNP
cord-256444-grw5s2pf	1565	17	in	in	IN
cord-256444-grw5s2pf	1565	18	vitro	vitro	FW
cord-256444-grw5s2pf	1565	19	of	of	IN
cord-256444-grw5s2pf	1565	20	a	a	DT
cord-256444-grw5s2pf	1565	21	spanning	span	VBG
cord-256444-grw5s2pf	1565	22	membrane	membrane	NN
cord-256444-grw5s2pf	1565	23	protein	protein	NN
cord-256444-grw5s2pf	1565	24	of	of	IN
cord-256444-grw5s2pf	1565	25	the	the	DT
cord-256444-grw5s2pf	1565	26	endoplasmic	endoplasmic	NN
cord-256444-grw5s2pf	1565	27	reticulum	reticulum	NN
cord-256444-grw5s2pf	1565	28	:	:	:
cord-256444-grw5s2pf	1565	29	The	the	DT
cord-256444-grw5s2pf	1565	30	E	e	NN
cord-256444-grw5s2pf	1565	31	l	l	NN
cord-256444-grw5s2pf	1565	32	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1565	33	of	of	IN
cord-256444-grw5s2pf	1565	34	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1565	35	mouse	mouse	NN
cord-256444-grw5s2pf	1565	36	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1565	37	virus	virus	NN
cord-256444-grw5s2pf	1565	38	A59	A59	NNP
cord-256444-grw5s2pf	1566	1	The	the	DT
cord-256444-grw5s2pf	1566	2	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1566	3	membrane	membrane	NN
cord-256444-grw5s2pf	1566	4	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1566	5	Analysis	analysis	NN
cord-256444-grw5s2pf	1566	6	of	of	IN
cord-256444-grw5s2pf	1566	7	murine	murine	JJ
cord-256444-grw5s2pf	1566	8	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1566	9	surface	surface	NN
cord-256444-grw5s2pf	1566	10	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1566	11	functions	function	NNS
cord-256444-grw5s2pf	1566	12	by	by	IN
cord-256444-grw5s2pf	1566	13	using	use	VBG
cord-256444-grw5s2pf	1566	14	monoclonal	monoclonal	JJ
cord-256444-grw5s2pf	1566	15	antibodies	antibody	NNS
cord-256444-grw5s2pf	1566	16	Evolution	Evolution	NNP
cord-256444-grw5s2pf	1566	17	of	of	IN
cord-256444-grw5s2pf	1566	18	mouse	mouse	NN
cord-256444-grw5s2pf	1566	19	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1566	20	virus	virus	NN
cord-256444-grw5s2pf	1566	21	:	:	:
cord-256444-grw5s2pf	1566	22	Detection	detection	NN
cord-256444-grw5s2pf	1566	23	and	and	CC
cord-256444-grw5s2pf	1566	24	characterization	characterization	NN
cord-256444-grw5s2pf	1566	25	of	of	IN
cord-256444-grw5s2pf	1566	26	spike	spike	NN
cord-256444-grw5s2pf	1566	27	deletion	deletion	NN
cord-256444-grw5s2pf	1566	28	variants	variant	NNS
cord-256444-grw5s2pf	1566	29	during	during	IN
cord-256444-grw5s2pf	1566	30	persistent	persistent	JJ
cord-256444-grw5s2pf	1566	31	infection	infection	NN
cord-256444-grw5s2pf	1566	32	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1566	33	minus	minus	JJ
cord-256444-grw5s2pf	1566	34	-	-	HYPH
cord-256444-grw5s2pf	1566	35	strand	strand	NN
cord-256444-grw5s2pf	1566	36	RNA	RNA	NNP
cord-256444-grw5s2pf	1566	37	synthesis	synthesis	NN
cord-256444-grw5s2pf	1566	38	and	and	CC
cord-256444-grw5s2pf	1566	39	effect	effect	NN
cord-256444-grw5s2pf	1566	40	of	of	IN
cord-256444-grw5s2pf	1566	41	cycloheximide	cycloheximide	NN
cord-256444-grw5s2pf	1566	42	on	on	IN
cord-256444-grw5s2pf	1566	43	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1566	44	RNA	RNA	NNP
cord-256444-grw5s2pf	1566	45	synthesis	synthesis	NN
cord-256444-grw5s2pf	1566	46	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1566	47	transcription	transcription	NN
cord-256444-grw5s2pf	1566	48	:	:	:
cord-256444-grw5s2pf	1567	1	Subgenomic	subgenomic	JJ
cord-256444-grw5s2pf	1567	2	mouse	mouse	NN
cord-256444-grw5s2pf	1567	3	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1567	4	virus	virus	NN
cord-256444-grw5s2pf	1567	5	replicative	replicative	JJ
cord-256444-grw5s2pf	1567	6	intermediates	intermediate	NNS
cord-256444-grw5s2pf	1567	7	function	function	VBP
cord-256444-grw5s2pf	1567	8	in	in	IN
cord-256444-grw5s2pf	1567	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1567	10	synthesis	synthesis	NN
cord-256444-grw5s2pf	1567	11	Persistent	persistent	JJ
cord-256444-grw5s2pf	1567	12	infection	infection	NN
cord-256444-grw5s2pf	1567	13	of	of	IN
cord-256444-grw5s2pf	1567	14	cultured	cultured	JJ
cord-256444-grw5s2pf	1567	15	cells	cell	NNS
cord-256444-grw5s2pf	1567	16	with	with	IN
cord-256444-grw5s2pf	1567	17	mouse	mouse	NN
cord-256444-grw5s2pf	1567	18	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1567	19	virus	virus	NN
cord-256444-grw5s2pf	1567	20	(	(	-LRB-
cord-256444-grw5s2pf	1567	21	MHV	mhv	NN
cord-256444-grw5s2pf	1567	22	)	)	-RRB-
cord-256444-grw5s2pf	1567	23	results	result	VBZ
cord-256444-grw5s2pf	1567	24	from	from	IN
cord-256444-grw5s2pf	1567	25	epigenetic	epigenetic	JJ
cord-256444-grw5s2pf	1567	26	expression	expression	NN
cord-256444-grw5s2pf	1567	27	of	of	IN
cord-256444-grw5s2pf	1567	28	the	the	DT
cord-256444-grw5s2pf	1567	29	MHV	MHV	NNP
cord-256444-grw5s2pf	1567	30	receptor	receptor	NN
cord-256444-grw5s2pf	1567	31	Evidence	evidence	NN
cord-256444-grw5s2pf	1567	32	for	for	IN
cord-256444-grw5s2pf	1567	33	new	new	JJ
cord-256444-grw5s2pf	1567	34	transcriptional	transcriptional	JJ
cord-256444-grw5s2pf	1567	35	units	unit	NNS
cord-256444-grw5s2pf	1567	36	encoded	encode	VBN
cord-256444-grw5s2pf	1567	37	at	at	IN
cord-256444-grw5s2pf	1567	38	the	the	DT
cord-256444-grw5s2pf	1567	39	3	3	CD
cord-256444-grw5s2pf	1567	40	'	'	NN
cord-256444-grw5s2pf	1567	41	end	end	NN
cord-256444-grw5s2pf	1567	42	of	of	IN
cord-256444-grw5s2pf	1567	43	the	the	DT
cord-256444-grw5s2pf	1567	44	mouse	mouse	NN
cord-256444-grw5s2pf	1567	45	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1567	46	virus	virus	NN
cord-256444-grw5s2pf	1567	47	genome	genome	NN
cord-256444-grw5s2pf	1567	48	Genetics	Genetics	NNP
cord-256444-grw5s2pf	1567	49	of	of	IN
cord-256444-grw5s2pf	1567	50	mouse	mouse	NNP
cord-256444-grw5s2pf	1567	51	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1567	52	virus	virus	NN
cord-256444-grw5s2pf	1567	53	transcription	transcription	NN
cord-256444-grw5s2pf	1567	54	:	:	:
cord-256444-grw5s2pf	1567	55	Identification	identification	NN
cord-256444-grw5s2pf	1567	56	of	of	IN
cord-256444-grw5s2pf	1567	57	cistrons	cistron	NNS
cord-256444-grw5s2pf	1567	58	which	which	WDT
cord-256444-grw5s2pf	1567	59	may	may	MD
cord-256444-grw5s2pf	1567	60	function	function	VB
cord-256444-grw5s2pf	1567	61	in	in	IN
cord-256444-grw5s2pf	1567	62	positive	positive	JJ
cord-256444-grw5s2pf	1567	63	and	and	CC
cord-256444-grw5s2pf	1567	64	negative	negative	JJ
cord-256444-grw5s2pf	1567	65	strand	strand	NN
cord-256444-grw5s2pf	1567	66	RNA	RNA	NNP
cord-256444-grw5s2pf	1567	67	synthesis	synthesis	NN
cord-256444-grw5s2pf	1567	68	Nucleotide	Nucleotide	NNP
cord-256444-grw5s2pf	1567	69	sequence	sequence	NN
cord-256444-grw5s2pf	1568	1	ofthe	ofthe	DT
cord-256444-grw5s2pf	1568	2	gene	gene	NN
cord-256444-grw5s2pf	1568	3	encoding	encode	VBG
cord-256444-grw5s2pf	1568	4	the	the	DT
cord-256444-grw5s2pf	1568	5	surface	surface	NN
cord-256444-grw5s2pf	1568	6	projection	projection	NN
cord-256444-grw5s2pf	1568	7	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1568	8	of	of	IN
cord-256444-grw5s2pf	1568	9	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1568	10	MHV	MHV	NNP
cord-256444-grw5s2pf	1568	11	-	-	HYPH
cord-256444-grw5s2pf	1568	12	JHM	JHM	NNP
cord-256444-grw5s2pf	1568	13	Acylation	Acylation	NNP
cord-256444-grw5s2pf	1568	14	of	of	IN
cord-256444-grw5s2pf	1568	15	viral	viral	JJ
cord-256444-grw5s2pf	1568	16	spike	spike	NN
cord-256444-grw5s2pf	1568	17	glycoproteins	glycoprotein	NNS
cord-256444-grw5s2pf	1568	18	:	:	:
cord-256444-grw5s2pf	1569	1	A	a	DT
cord-256444-grw5s2pf	1569	2	feature	feature	NN
cord-256444-grw5s2pf	1569	3	of	of	IN
cord-256444-grw5s2pf	1569	4	enveloped	envelop	VBN
cord-256444-grw5s2pf	1569	5	RNA	RNA	NNP
cord-256444-grw5s2pf	1569	6	viruses	virus	NNS
cord-256444-grw5s2pf	1569	7	Bovine	bovine	JJ
cord-256444-grw5s2pf	1569	8	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1569	9	uses	use	VBZ
cord-256444-grw5s2pf	1569	10	N	n	CD
cord-256444-grw5s2pf	1569	11	-	-	HYPH
cord-256444-grw5s2pf	1569	12	acetyl-9	acetyl-9	NNP
cord-256444-grw5s2pf	1569	13	-	-	HYPH
cord-256444-grw5s2pf	1569	14	0-acetylneuraminic	0-acetylneuraminic	CD
cord-256444-grw5s2pf	1569	15	acid	acid	NN
cord-256444-grw5s2pf	1569	16	as	as	IN
cord-256444-grw5s2pf	1569	17	a	a	DT
cord-256444-grw5s2pf	1569	18	receptor	receptor	NN
cord-256444-grw5s2pf	1569	19	determinant	determinant	NN
cord-256444-grw5s2pf	1569	20	to	to	TO
cord-256444-grw5s2pf	1569	21	initiate	initiate	VB
cord-256444-grw5s2pf	1569	22	the	the	DT
cord-256444-grw5s2pf	1569	23	infection	infection	NN
cord-256444-grw5s2pf	1569	24	of	of	IN
cord-256444-grw5s2pf	1569	25	cultured	cultured	JJ
cord-256444-grw5s2pf	1569	26	cells	cell	NNS
cord-256444-grw5s2pf	1570	1	Hemagglutinating	Hemagglutinating	NNP
cord-256444-grw5s2pf	1570	2	encephalomyelitis	encephalomyelitis	NN
cord-256444-grw5s2pf	1570	3	virus	virus	NN
cord-256444-grw5s2pf	1570	4	attaches	attach	VBZ
cord-256444-grw5s2pf	1570	5	to	to	IN
cord-256444-grw5s2pf	1570	6	N	n	CD
cord-256444-grw5s2pf	1570	7	-	-	HYPH
cord-256444-grw5s2pf	1570	8	acetyl-9	acetyl-9	NNP
cord-256444-grw5s2pf	1570	9	-	-	HYPH
cord-256444-grw5s2pf	1570	10	0-acetylneuraminic	0-acetylneuraminic	CD
cord-256444-grw5s2pf	1570	11	acidcontaining	acidcontaining	NN
cord-256444-grw5s2pf	1570	12	receptors	receptor	NNS
cord-256444-grw5s2pf	1570	13	on	on	IN
cord-256444-grw5s2pf	1570	14	erythrocytes	erythrocyte	NNS
cord-256444-grw5s2pf	1570	15	:	:	:
cord-256444-grw5s2pf	1571	1	Comparison	comparison	NN
cord-256444-grw5s2pf	1571	2	with	with	IN
cord-256444-grw5s2pf	1571	3	bovine	bovine	JJ
cord-256444-grw5s2pf	1571	4	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1571	5	and	and	CC
cord-256444-grw5s2pf	1571	6	influenza	influenza	NN
cord-256444-grw5s2pf	1571	7	C	c	NN
cord-256444-grw5s2pf	1571	8	virus	virus	NN
cord-256444-grw5s2pf	1572	1	The	the	DT
cord-256444-grw5s2pf	1572	2	S	S	NNP
cord-256444-grw5s2pf	1572	3	protein	protein	NN
cord-256444-grw5s2pf	1572	4	of	of	IN
cord-256444-grw5s2pf	1572	5	bovine	bovine	JJ
cord-256444-grw5s2pf	1572	6	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1572	7	is	be	VBZ
cord-256444-grw5s2pf	1572	8	a	a	DT
cord-256444-grw5s2pf	1572	9	hemagglutinin	hemagglutinin	NN
cord-256444-grw5s2pf	1572	10	recognizing	recognize	VBG
cord-256444-grw5s2pf	1572	11	9	9	CD
cord-256444-grw5s2pf	1572	12	-	-	SYM
cord-256444-grw5s2pf	1572	13	0-acetylated	0-acetylated	CD
cord-256444-grw5s2pf	1572	14	sialic	sialic	NN
cord-256444-grw5s2pf	1572	15	acid	acid	NN
cord-256444-grw5s2pf	1572	16	as	as	IN
cord-256444-grw5s2pf	1572	17	a	a	DT
cord-256444-grw5s2pf	1572	18	receptor	receptor	NN
cord-256444-grw5s2pf	1572	19	determinant	determinant	NN
cord-256444-grw5s2pf	1572	20	Isolated	isolate	VBN
cord-256444-grw5s2pf	1572	21	HE	HE	NNP
cord-256444-grw5s2pf	1572	22	-	-	HYPH
cord-256444-grw5s2pf	1572	23	protein	protein	NN
cord-256444-grw5s2pf	1572	24	from	from	IN
cord-256444-grw5s2pf	1572	25	hemagglutinating	hemagglutinate	VBG
cord-256444-grw5s2pf	1572	26	encephalomyelitis	encephalomyelitis	NN
cord-256444-grw5s2pf	1572	27	virus	virus	NN
cord-256444-grw5s2pf	1572	28	and	and	CC
cord-256444-grw5s2pf	1572	29	bovine	bovine	JJ
cord-256444-grw5s2pf	1572	30	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1572	31	has	have	VBZ
cord-256444-grw5s2pf	1572	32	receptordestroying	receptordestroye	VBG
cord-256444-grw5s2pf	1572	33	and	and	CC
cord-256444-grw5s2pf	1572	34	receptor	receptor	NN
cord-256444-grw5s2pf	1572	35	-	-	HYPH
cord-256444-grw5s2pf	1572	36	binding	bind	VBG
cord-256444-grw5s2pf	1572	37	activity	activity	NN
cord-256444-grw5s2pf	1573	1	Neuraminidase	Neuraminidase	NNP
cord-256444-grw5s2pf	1573	2	treatment	treatment	NN
cord-256444-grw5s2pf	1573	3	of	of	IN
cord-256444-grw5s2pf	1573	4	avian	avian	JJ
cord-256444-grw5s2pf	1573	5	infectious	infectious	JJ
cord-256444-grw5s2pf	1573	6	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1573	7	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1573	8	reveals	reveal	VBZ
cord-256444-grw5s2pf	1573	9	a	a	DT
cord-256444-grw5s2pf	1573	10	hemagglutinating	hemagglutinate	VBG
cord-256444-grw5s2pf	1573	11	activity	activity	NN
cord-256444-grw5s2pf	1573	12	that	that	WDT
cord-256444-grw5s2pf	1573	13	is	be	VBZ
cord-256444-grw5s2pf	1573	14	dependent	dependent	JJ
cord-256444-grw5s2pf	1573	15	on	on	IN
cord-256444-grw5s2pf	1573	16	sialic	sialic	JJ
cord-256444-grw5s2pf	1573	17	acid	acid	NN
cord-256444-grw5s2pf	1573	18	-	-	HYPH
cord-256444-grw5s2pf	1573	19	containing	contain	VBG
cord-256444-grw5s2pf	1573	20	receptors	receptor	NNS
cord-256444-grw5s2pf	1573	21	on	on	IN
cord-256444-grw5s2pf	1573	22	erythrocytes	erythrocyte	NNS
cord-256444-grw5s2pf	1573	23	Murine	murine	JJ
cord-256444-grw5s2pf	1573	24	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1574	1	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	1574	2	protein	protein	NN
cord-256444-grw5s2pf	1574	3	ns2	ns2	NNP
cord-256444-grw5s2pf	1574	4	is	be	VBZ
cord-256444-grw5s2pf	1574	5	not	not	RB
cord-256444-grw5s2pf	1574	6	essential	essential	JJ
cord-256444-grw5s2pf	1574	7	for	for	IN
cord-256444-grw5s2pf	1574	8	virus	virus	NN
cord-256444-grw5s2pf	1574	9	replication	replication	NN
cord-256444-grw5s2pf	1574	10	in	in	IN
cord-256444-grw5s2pf	1574	11	transformed	transform	VBN
cord-256444-grw5s2pf	1574	12	cells	cell	NNS
cord-256444-grw5s2pf	1575	1	The	the	DT
cord-256444-grw5s2pf	1575	2	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1575	3	protein	protein	NN
cord-256444-grw5s2pf	1575	4	gene	gene	NN
cord-256444-grw5s2pf	1575	5	of	of	IN
cord-256444-grw5s2pf	1575	6	bovine	bovine	JJ
cord-256444-grw5s2pf	1575	7	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1575	8	is	be	VBZ
cord-256444-grw5s2pf	1575	9	bicistronic	bicistronic	JJ
cord-256444-grw5s2pf	1575	10	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1575	11	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1575	12	minusstrand	minusstrand	NN
cord-256444-grw5s2pf	1575	13	RNAs	rna	NNS
cord-256444-grw5s2pf	1575	14	and	and	CC
cord-256444-grw5s2pf	1575	15	the	the	DT
cord-256444-grw5s2pf	1575	16	potential	potential	NN
cord-256444-grw5s2pf	1575	17	for	for	IN
cord-256444-grw5s2pf	1575	18	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1575	19	replicons	replicons	NNPS
cord-256444-grw5s2pf	1575	20	Minus	Minus	NNP
cord-256444-grw5s2pf	1575	21	-	-	HYPH
cord-256444-grw5s2pf	1575	22	strand	strand	NN
cord-256444-grw5s2pf	1575	23	copies	copy	NNS
cord-256444-grw5s2pf	1575	24	of	of	IN
cord-256444-grw5s2pf	1575	25	replicating	replicate	VBG
cord-256444-grw5s2pf	1575	26	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1575	27	mRNAs	mrnas	TO
cord-256444-grw5s2pf	1575	28	contain	contain	VBP
cord-256444-grw5s2pf	1575	29	antileaders	antileader	NNS
cord-256444-grw5s2pf	1575	30	Expression	expression	NN
cord-256444-grw5s2pf	1575	31	and	and	CC
cord-256444-grw5s2pf	1575	32	characterization	characterization	NN
cord-256444-grw5s2pf	1575	33	of	of	IN
cord-256444-grw5s2pf	1575	34	a	a	DT
cord-256444-grw5s2pf	1575	35	recombinant	recombinant	JJ
cord-256444-grw5s2pf	1575	36	murine	murine	JJ
cord-256444-grw5s2pf	1575	37	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1575	38	3C	3c	NN
cord-256444-grw5s2pf	1575	39	-	-	HYPH
cord-256444-grw5s2pf	1575	40	like	like	JJ
cord-256444-grw5s2pf	1575	41	proteinase	proteinase	NN
cord-256444-grw5s2pf	1575	42	Identification	identification	NN
cord-256444-grw5s2pf	1575	43	of	of	IN
cord-256444-grw5s2pf	1575	44	a	a	DT
cord-256444-grw5s2pf	1575	45	new	new	JJ
cord-256444-grw5s2pf	1575	46	transcriptional	transcriptional	JJ
cord-256444-grw5s2pf	1575	47	initiation	initiation	NN
cord-256444-grw5s2pf	1575	48	site	site	NN
cord-256444-grw5s2pf	1575	49	and	and	CC
cord-256444-grw5s2pf	1575	50	the	the	DT
cord-256444-grw5s2pf	1575	51	corresponding	corresponding	JJ
cord-256444-grw5s2pf	1575	52	functional	functional	JJ
cord-256444-grw5s2pf	1575	53	gene	gene	NN
cord-256444-grw5s2pf	1575	54	2b	2b	CD
cord-256444-grw5s2pf	1575	55	in	in	IN
cord-256444-grw5s2pf	1575	56	the	the	DT
cord-256444-grw5s2pf	1575	57	murine	murine	JJ
cord-256444-grw5s2pf	1575	58	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1575	59	RNA	RNA	NNP
cord-256444-grw5s2pf	1575	60	genome	genome	NN
cord-256444-grw5s2pf	1576	1	In	in	IN
cord-256444-grw5s2pf	1576	2	vitro	vitro	FW
cord-256444-grw5s2pf	1576	3	interaction	interaction	NN
cord-256444-grw5s2pf	1576	4	of	of	IN
cord-256444-grw5s2pf	1576	5	mouse	mouse	NNP
cord-256444-grw5s2pf	1576	6	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1576	7	virus	virus	NN
cord-256444-grw5s2pf	1576	8	and	and	CC
cord-256444-grw5s2pf	1576	9	macrophages	macrophage	NNS
cord-256444-grw5s2pf	1576	10	from	from	IN
cord-256444-grw5s2pf	1576	11	gneetically	gneetically	RB
cord-256444-grw5s2pf	1576	12	resistant	resistant	JJ
cord-256444-grw5s2pf	1576	13	mice	mouse	NNS
cord-256444-grw5s2pf	1576	14	.	.	.
cord-256444-grw5s2pf	1577	1	I.	I.	NNP
cord-256444-grw5s2pf	1577	2	Adsorption	Adsorption	NNP
cord-256444-grw5s2pf	1577	3	of	of	IN
cord-256444-grw5s2pf	1577	4	virus	virus	NN
cord-256444-grw5s2pf	1577	5	and	and	CC
cord-256444-grw5s2pf	1577	6	growth	growth	NN
cord-256444-grw5s2pf	1577	7	curves	curve	NNS
cord-256444-grw5s2pf	1578	1	The	the	DT
cord-256444-grw5s2pf	1578	2	Coronaviridae	Coronaviridae	NNP
cord-256444-grw5s2pf	1578	3	The	the	DT
cord-256444-grw5s2pf	1578	4	Coronaviridae	Coronaviridae	NNP
cord-256444-grw5s2pf	1578	5	:	:	:
cord-256444-grw5s2pf	1578	6	An	an	DT
cord-256444-grw5s2pf	1578	7	introduction	introduction	NN
cord-256444-grw5s2pf	1579	1	The	the	DT
cord-256444-grw5s2pf	1579	2	small	small	JJ
cord-256444-grw5s2pf	1579	3	membrane	membrane	NN
cord-256444-grw5s2pf	1579	4	protein	protein	NN
cord-256444-grw5s2pf	1579	5	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1579	6	JHM	JHM	NNP
cord-256444-grw5s2pf	1579	7	:	:	:
cord-256444-grw5s2pf	1580	1	Intracellular	Intracellular	NNP
cord-256444-grw5s2pf	1580	2	protein	protein	NN
cord-256444-grw5s2pf	1580	3	synthesis	synthesis	NN
cord-256444-grw5s2pf	1580	4	Monoclonal	Monoclonal	NNP
cord-256444-grw5s2pf	1580	5	antibody	antibody	NN
cord-256444-grw5s2pf	1580	6	to	to	IN
cord-256444-grw5s2pf	1580	7	the	the	DT
cord-256444-grw5s2pf	1580	8	receptor	receptor	NN
cord-256444-grw5s2pf	1580	9	for	for	IN
cord-256444-grw5s2pf	1580	10	murine	murine	JJ
cord-256444-grw5s2pf	1580	11	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1580	12	MHV	mhv	NN
cord-256444-grw5s2pf	1580	13	-	-	HYPH
cord-256444-grw5s2pf	1580	14	A59	A59	NNP
cord-256444-grw5s2pf	1580	15	inhibits	inhibit	VBZ
cord-256444-grw5s2pf	1580	16	viral	viral	JJ
cord-256444-grw5s2pf	1580	17	replication	replication	NN
cord-256444-grw5s2pf	1580	18	in	in	IN
cord-256444-grw5s2pf	1580	19	vivo	vivo	NNP
cord-256444-grw5s2pf	1580	20	Identification	identification	NN
cord-256444-grw5s2pf	1580	21	of	of	IN
cord-256444-grw5s2pf	1580	22	a	a	DT
cord-256444-grw5s2pf	1580	23	new	new	JJ
cord-256444-grw5s2pf	1580	24	membrane	membrane	NN
cord-256444-grw5s2pf	1580	25	-	-	HYPH
cord-256444-grw5s2pf	1580	26	associated	associate	VBN
cord-256444-grw5s2pf	1580	27	polypeptide	polypeptide	NN
cord-256444-grw5s2pf	1580	28	specified	specify	VBN
cord-256444-grw5s2pf	1580	29	by	by	IN
cord-256444-grw5s2pf	1580	30	the	the	DT
cord-256444-grw5s2pf	1580	31	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1580	32	infectious	infectious	JJ
cord-256444-grw5s2pf	1580	33	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1580	34	virus	virus	NN
cord-256444-grw5s2pf	1580	35	Toroviruses	Toroviruses	NNPS
cord-256444-grw5s2pf	1580	36	:	:	:
cord-256444-grw5s2pf	1580	37	Replication	replication	NN
cord-256444-grw5s2pf	1580	38	,	,	,
cord-256444-grw5s2pf	1580	39	evolution	evolution	NN
cord-256444-grw5s2pf	1580	40	and	and	CC
cord-256444-grw5s2pf	1580	41	comparison	comparison	NN
cord-256444-grw5s2pf	1580	42	with	with	IN
cord-256444-grw5s2pf	1580	43	other	other	JJ
cord-256444-grw5s2pf	1580	44	members	member	NNS
cord-256444-grw5s2pf	1580	45	of	of	IN
cord-256444-grw5s2pf	1580	46	the	the	DT
cord-256444-grw5s2pf	1580	47	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1580	48	-	-	HYPH
cord-256444-grw5s2pf	1580	49	like	like	JJ
cord-256444-grw5s2pf	1580	50	superfamily	superfamily	NN
cord-256444-grw5s2pf	1581	1	The	the	DT
cord-256444-grw5s2pf	1581	2	molecular	molecular	JJ
cord-256444-grw5s2pf	1581	3	biology	biology	NN
cord-256444-grw5s2pf	1581	4	of	of	IN
cord-256444-grw5s2pf	1581	5	toroviruses	toroviruse	NNS
cord-256444-grw5s2pf	1582	1	The	the	DT
cord-256444-grw5s2pf	1582	2	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1582	3	superfamily	superfamily	NN
cord-256444-grw5s2pf	1582	4	Comparison	comparison	NN
cord-256444-grw5s2pf	1582	5	of	of	IN
cord-256444-grw5s2pf	1582	6	the	the	DT
cord-256444-grw5s2pf	1582	7	genome	genome	NN
cord-256444-grw5s2pf	1582	8	organization	organization	NN
cord-256444-grw5s2pf	1582	9	of	of	IN
cord-256444-grw5s2pf	1582	10	toro	toro	NNP
cord-256444-grw5s2pf	1582	11	-	-	HYPH
cord-256444-grw5s2pf	1582	12	and	and	CC
cord-256444-grw5s2pf	1582	13	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1582	14	:	:	:
cord-256444-grw5s2pf	1582	15	Evidence	evidence	NN
cord-256444-grw5s2pf	1582	16	for	for	IN
cord-256444-grw5s2pf	1582	17	two	two	CD
cord-256444-grw5s2pf	1582	18	nonhomologous	nonhomologous	NNP
cord-256444-grw5s2pf	1582	19	RNA	RNA	NNP
cord-256444-grw5s2pf	1582	20	recombination	recombination	NN
cord-256444-grw5s2pf	1582	21	events	event	NNS
cord-256444-grw5s2pf	1582	22	during	during	IN
cord-256444-grw5s2pf	1582	23	Berne	Berne	NNP
cord-256444-grw5s2pf	1582	24	virus	virus	NN
cord-256444-grw5s2pf	1582	25	evolution	evolution	NN
cord-256444-grw5s2pf	1582	26	Sequence	sequence	NN
cord-256444-grw5s2pf	1582	27	and	and	CC
cord-256444-grw5s2pf	1582	28	translation	translation	NN
cord-256444-grw5s2pf	1582	29	of	of	IN
cord-256444-grw5s2pf	1582	30	the	the	DT
cord-256444-grw5s2pf	1582	31	murine	murine	JJ
cord-256444-grw5s2pf	1582	32	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1582	33	5'-end	5'-end	CD
cord-256444-grw5s2pf	1582	34	genomic	genomic	JJ
cord-256444-grw5s2pf	1582	35	RNA	RNA	NNP
cord-256444-grw5s2pf	1582	36	reveals	reveal	VBZ
cord-256444-grw5s2pf	1582	37	the	the	DT
cord-256444-grw5s2pf	1582	38	N	n	CD
cord-256444-grw5s2pf	1582	39	-	-	HYPH
cord-256444-grw5s2pf	1582	40	terminal	terminal	JJ
cord-256444-grw5s2pf	1582	41	structure	structure	NN
cord-256444-grw5s2pf	1582	42	of	of	IN
cord-256444-grw5s2pf	1582	43	the	the	DT
cord-256444-grw5s2pf	1582	44	putative	putative	JJ
cord-256444-grw5s2pf	1582	45	RNA	RNA	NNP
cord-256444-grw5s2pf	1582	46	polymerase	polymerase	NN
cord-256444-grw5s2pf	1582	47	Ribosomal	Ribosomal	NNP
cord-256444-grw5s2pf	1582	48	pausing	pause	VBG
cord-256444-grw5s2pf	1582	49	during	during	IN
cord-256444-grw5s2pf	1582	50	translation	translation	NN
cord-256444-grw5s2pf	1582	51	of	of	IN
cord-256444-grw5s2pf	1582	52	an	an	DT
cord-256444-grw5s2pf	1582	53	RNA	RNA	NNP
cord-256444-grw5s2pf	1582	54	pseudoknot	pseudoknot	NN
cord-256444-grw5s2pf	1582	55	Isolation	isolation	NN
cord-256444-grw5s2pf	1582	56	and	and	CC
cord-256444-grw5s2pf	1582	57	identification	identification	NN
cord-256444-grw5s2pf	1582	58	of	of	IN
cord-256444-grw5s2pf	1582	59	virus	virus	NN
cord-256444-grw5s2pf	1582	60	-	-	HYPH
cord-256444-grw5s2pf	1582	61	specific	specific	JJ
cord-256444-grw5s2pf	1582	62	mRNA	mrna	NN
cord-256444-grw5s2pf	1582	63	in	in	IN
cord-256444-grw5s2pf	1582	64	cells	cell	NNS
cord-256444-grw5s2pf	1582	65	infected	infect	VBN
cord-256444-grw5s2pf	1582	66	with	with	IN
cord-256444-grw5s2pf	1582	67	mouth	mouth	NN
cord-256444-grw5s2pf	1582	68	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1582	69	virus	virus	NN
cord-256444-grw5s2pf	1582	70	(	(	-LRB-
cord-256444-grw5s2pf	1582	71	MHV	mhv	NN
cord-256444-grw5s2pf	1582	72	-	-	HYPH
cord-256444-grw5s2pf	1582	73	ASS	ass	NN
cord-256444-grw5s2pf	1582	74	)	)	-RRB-
cord-256444-grw5s2pf	1583	1	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1583	2	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1583	3	synthesis	synthesis	NN
cord-256444-grw5s2pf	1583	4	involves	involve	VBZ
cord-256444-grw5s2pf	1583	5	fusion	fusion	NN
cord-256444-grw5s2pf	1583	6	of	of	IN
cord-256444-grw5s2pf	1583	7	non	non	JJ
cord-256444-grw5s2pf	1583	8	-	-	JJ
cord-256444-grw5s2pf	1583	9	contiguous	contiguous	JJ
cord-256444-grw5s2pf	1583	10	sequences	sequence	NNS
cord-256444-grw5s2pf	1584	1	Proteolytic	proteolytic	JJ
cord-256444-grw5s2pf	1584	2	cleavage	cleavage	NN
cord-256444-grw5s2pf	1584	3	of	of	IN
cord-256444-grw5s2pf	1584	4	the	the	DT
cord-256444-grw5s2pf	1584	5	murine	murine	JJ
cord-256444-grw5s2pf	1584	6	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1584	7	surface	surface	NN
cord-256444-grw5s2pf	1584	8	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1584	9	is	be	VBZ
cord-256444-grw5s2pf	1584	10	not	not	RB
cord-256444-grw5s2pf	1584	11	required	require	VBN
cord-256444-grw5s2pf	1584	12	for	for	IN
cord-256444-grw5s2pf	1584	13	fusion	fusion	NN
cord-256444-grw5s2pf	1584	14	activity	activity	NN
cord-256444-grw5s2pf	1584	15	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1584	16	multiplication	multiplication	NN
cord-256444-grw5s2pf	1584	17	strategy	strategy	NN
cord-256444-grw5s2pf	1584	18	Identification	identification	NN
cord-256444-grw5s2pf	1584	19	and	and	CC
cord-256444-grw5s2pf	1584	20	characterization	characterization	NN
cord-256444-grw5s2pf	1584	21	of	of	IN
cord-256444-grw5s2pf	1584	22	virus	virus	NN
cord-256444-grw5s2pf	1584	23	-	-	HYPH
cord-256444-grw5s2pf	1584	24	specified	specify	VBN
cord-256444-grw5s2pf	1584	25	RNA	RNA	NNP
cord-256444-grw5s2pf	1584	26	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1584	27	multiplication	multiplication	NN
cord-256444-grw5s2pf	1584	28	strategy	strategy	NN
cord-256444-grw5s2pf	1584	29	.	.	.
cord-256444-grw5s2pf	1585	1	11	11	CD
cord-256444-grw5s2pf	1585	2	.	.	.
cord-256444-grw5s2pf	1586	1	Mapping	map	VBG
cord-256444-grw5s2pf	1586	2	the	the	DT
cord-256444-grw5s2pf	1586	3	avian	avian	JJ
cord-256444-grw5s2pf	1586	4	infectious	infectious	JJ
cord-256444-grw5s2pf	1586	5	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1586	6	virus	virus	NN
cord-256444-grw5s2pf	1586	7	intracellular	intracellular	JJ
cord-256444-grw5s2pf	1586	8	RNA	RNA	NNP
cord-256444-grw5s2pf	1586	9	species	specie	NNS
cord-256444-grw5s2pf	1586	10	to	to	IN
cord-256444-grw5s2pf	1586	11	the	the	DT
cord-256444-grw5s2pf	1586	12	genome	genome	NN
cord-256444-grw5s2pf	1586	13	Synthesis	synthesis	NN
cord-256444-grw5s2pf	1586	14	of	of	IN
cord-256444-grw5s2pf	1586	15	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1586	16	mRNAs	mrnas	XX
cord-256444-grw5s2pf	1586	17	:	:	:
cord-256444-grw5s2pf	1587	1	Kinetics	kinetic	NNS
cord-256444-grw5s2pf	1587	2	of	of	IN
cord-256444-grw5s2pf	1587	3	inactivation	inactivation	NN
cord-256444-grw5s2pf	1587	4	of	of	IN
cord-256444-grw5s2pf	1587	5	infectious	infectious	JJ
cord-256444-grw5s2pf	1587	6	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1587	7	virus	virus	NN
cord-256444-grw5s2pf	1587	8	RNA	RNA	NNP
cord-256444-grw5s2pf	1587	9	synthesis	synthesis	NN
cord-256444-grw5s2pf	1587	10	by	by	IN
cord-256444-grw5s2pf	1587	11	UV	uv	NN
cord-256444-grw5s2pf	1587	12	light	light	JJ
cord-256444-grw5s2pf	1587	13	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1587	14	proteins	protein	NNS
cord-256444-grw5s2pf	1587	15	:	:	:
cord-256444-grw5s2pf	1587	16	Structure	structure	NN
cord-256444-grw5s2pf	1587	17	and	and	CC
cord-256444-grw5s2pf	1587	18	function	function	NN
cord-256444-grw5s2pf	1587	19	of	of	IN
cord-256444-grw5s2pf	1587	20	the	the	DT
cord-256444-grw5s2pf	1587	21	oligosaccharides	oligosaccharide	NNS
cord-256444-grw5s2pf	1587	22	of	of	IN
cord-256444-grw5s2pf	1587	23	the	the	DT
cord-256444-grw5s2pf	1587	24	avian	avian	JJ
cord-256444-grw5s2pf	1587	25	infectious	infectious	JJ
cord-256444-grw5s2pf	1587	26	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1587	27	virus	virus	NN
cord-256444-grw5s2pf	1587	28	glycoproteins	glycoprotein	VBZ
cord-256444-grw5s2pf	1587	29	Phosphoproteins	Phosphoproteins	NNP
cord-256444-grw5s2pf	1587	30	of	of	IN
cord-256444-grw5s2pf	1587	31	murine	murine	JJ
cord-256444-grw5s2pf	1587	32	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1587	33	viruses	virus	NNS
cord-256444-grw5s2pf	1588	1	Specific	specific	JJ
cord-256444-grw5s2pf	1588	2	interaction	interaction	NN
cord-256444-grw5s2pf	1588	3	between	between	IN
cord-256444-grw5s2pf	1588	4	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1588	5	leader	leader	NN
cord-256444-grw5s2pf	1588	6	RNA	RNA	NNP
cord-256444-grw5s2pf	1588	7	and	and	CC
cord-256444-grw5s2pf	1588	8	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1588	9	protein	protein	NN
cord-256444-grw5s2pf	1588	10	Monoclonal	Monoclonal	NNP
cord-256444-grw5s2pf	1588	11	antibodies	antibody	NNS
cord-256444-grw5s2pf	1588	12	differentiate	differentiate	VBP
cord-256444-grw5s2pf	1588	13	between	between	IN
cord-256444-grw5s2pf	1588	14	the	the	DT
cord-256444-grw5s2pf	1588	15	haemagglutinating	haemagglutinating	NN
cord-256444-grw5s2pf	1588	16	and	and	CC
cord-256444-grw5s2pf	1588	17	the	the	DT
cord-256444-grw5s2pf	1588	18	receptordestroying	receptordestroye	VBG
cord-256444-grw5s2pf	1588	19	activities	activity	NNS
cord-256444-grw5s2pf	1588	20	of	of	IN
cord-256444-grw5s2pf	1588	21	bovine	bovine	JJ
cord-256444-grw5s2pf	1588	22	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1589	1	The	the	DT
cord-256444-grw5s2pf	1589	2	molecular	molecular	JJ
cord-256444-grw5s2pf	1589	3	biology	biology	NN
cord-256444-grw5s2pf	1589	4	of	of	IN
cord-256444-grw5s2pf	1589	5	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1589	6	Isolation	Isolation	NNP
cord-256444-grw5s2pf	1589	7	of	of	IN
cord-256444-grw5s2pf	1589	8	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1589	9	envelope	envelope	NN
cord-256444-grw5s2pf	1589	10	glycoproteins	glycoprotein	NNS
cord-256444-grw5s2pf	1589	11	and	and	CC
cord-256444-grw5s2pf	1589	12	interaction	interaction	NN
cord-256444-grw5s2pf	1589	13	with	with	IN
cord-256444-grw5s2pf	1589	14	the	the	DT
cord-256444-grw5s2pf	1589	15	viral	viral	JJ
cord-256444-grw5s2pf	1589	16	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1589	17	Proteolytic	proteolytic	JJ
cord-256444-grw5s2pf	1589	18	cleavage	cleavage	NN
cord-256444-grw5s2pf	1589	19	of	of	IN
cord-256444-grw5s2pf	1589	20	the	the	DT
cord-256444-grw5s2pf	1589	21	E2	E2	NNP
cord-256444-grw5s2pf	1589	22	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1589	23	of	of	IN
cord-256444-grw5s2pf	1589	24	murine	murine	JJ
cord-256444-grw5s2pf	1589	25	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1589	26	:	:	:
cord-256444-grw5s2pf	1590	1	Activation	activation	NN
cord-256444-grw5s2pf	1590	2	of	of	IN
cord-256444-grw5s2pf	1590	3	cell	cell	NN
cord-256444-grw5s2pf	1590	4	fusing	fusing	NN
cord-256444-grw5s2pf	1590	5	activity	activity	NN
cord-256444-grw5s2pf	1590	6	of	of	IN
cord-256444-grw5s2pf	1590	7	virions	virion	NNS
cord-256444-grw5s2pf	1590	8	by	by	IN
cord-256444-grw5s2pf	1590	9	trypsin	trypsin	NN
cord-256444-grw5s2pf	1590	10	and	and	CC
cord-256444-grw5s2pf	1590	11	separation	separation	NN
cord-256444-grw5s2pf	1590	12	of	of	IN
cord-256444-grw5s2pf	1590	13	two	two	CD
cord-256444-grw5s2pf	1590	14	different	different	JJ
cord-256444-grw5s2pf	1590	15	90	90	CD
cord-256444-grw5s2pf	1590	16	K	k	NN
cord-256444-grw5s2pf	1590	17	cleavage	cleavage	NN
cord-256444-grw5s2pf	1590	18	fragments	fragment	NNS
cord-256444-grw5s2pf	1590	19	Conformational	Conformational	NNP
cord-256444-grw5s2pf	1590	20	change	change	NN
cord-256444-grw5s2pf	1590	21	of	of	IN
cord-256444-grw5s2pf	1590	22	the	the	DT
cord-256444-grw5s2pf	1590	23	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1590	24	peplomer	peplomer	NN
cord-256444-grw5s2pf	1590	25	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1590	26	at	at	IN
cord-256444-grw5s2pf	1590	27	pH	pH	NNP
cord-256444-grw5s2pf	1590	28	8.0	8.0	CD
cord-256444-grw5s2pf	1590	29	and	and	CC
cord-256444-grw5s2pf	1590	30	37	37	CD
cord-256444-grw5s2pf	1590	31	degrees	degree	NNS
cord-256444-grw5s2pf	1590	32	C	c	NN
cord-256444-grw5s2pf	1590	33	correlates	correlate	VBZ
cord-256444-grw5s2pf	1590	34	with	with	IN
cord-256444-grw5s2pf	1590	35	virus	virus	NN
cord-256444-grw5s2pf	1590	36	aggregation	aggregation	NN
cord-256444-grw5s2pf	1590	37	and	and	CC
cord-256444-grw5s2pf	1590	38	virus	virus	NN
cord-256444-grw5s2pf	1590	39	-	-	HYPH
cord-256444-grw5s2pf	1590	40	induced	induce	VBN
cord-256444-grw5s2pf	1590	41	cell	cell	NN
cord-256444-grw5s2pf	1590	42	fusion	fusion	NN
cord-256444-grw5s2pf	1590	43	Hemagglutination	Hemagglutination	NNP
cord-256444-grw5s2pf	1590	44	and	and	CC
cord-256444-grw5s2pf	1590	45	structural	structural	JJ
cord-256444-grw5s2pf	1590	46	polypeptides	polypeptide	NNS
cord-256444-grw5s2pf	1590	47	of	of	IN
cord-256444-grw5s2pf	1590	48	a	a	DT
cord-256444-grw5s2pf	1590	49	new	new	JJ
cord-256444-grw5s2pf	1590	50	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1590	51	associated	associate	VBN
cord-256444-grw5s2pf	1590	52	with	with	IN
cord-256444-grw5s2pf	1590	53	diarrhea	diarrhea	NN
cord-256444-grw5s2pf	1590	54	in	in	IN
cord-256444-grw5s2pf	1590	55	infant	infant	NN
cord-256444-grw5s2pf	1590	56	mice	mouse	NNS
cord-256444-grw5s2pf	1591	1	Analysis	analysis	NN
cord-256444-grw5s2pf	1591	2	ofreceptor	ofreceptor	NN
cord-256444-grw5s2pf	1591	3	-	-	HYPH
cord-256444-grw5s2pf	1591	4	binding	bind	VBG
cord-256444-grw5s2pf	1591	5	site	site	NN
cord-256444-grw5s2pf	1591	6	ofmurine	ofmurine	NN
cord-256444-grw5s2pf	1591	7	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1591	8	spike	spike	NN
cord-256444-grw5s2pf	1591	9	protein	protein	NN
cord-256444-grw5s2pf	1591	10	A	a	DT
cord-256444-grw5s2pf	1591	11	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1591	12	retention	retention	NN
cord-256444-grw5s2pf	1591	13	signal	signal	NN
cord-256444-grw5s2pf	1591	14	in	in	IN
cord-256444-grw5s2pf	1591	15	a	a	DT
cord-256444-grw5s2pf	1591	16	membranespanning	membranespanne	VBG
cord-256444-grw5s2pf	1591	17	domain	domain	NN
cord-256444-grw5s2pf	1591	18	of	of	IN
cord-256444-grw5s2pf	1591	19	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1591	20	E	E	NNP
cord-256444-grw5s2pf	1591	21	l	l	NN
cord-256444-grw5s2pf	1591	22	protein	protein	NN
cord-256444-grw5s2pf	1591	23	Fusion	Fusion	NNP
cord-256444-grw5s2pf	1591	24	formation	formation	NN
cord-256444-grw5s2pf	1591	25	by	by	IN
cord-256444-grw5s2pf	1591	26	the	the	DT
cord-256444-grw5s2pf	1591	27	uncleaved	uncleaved	JJ
cord-256444-grw5s2pf	1591	28	spike	spike	NN
cord-256444-grw5s2pf	1591	29	protein	protein	NN
cord-256444-grw5s2pf	1591	30	of	of	IN
cord-256444-grw5s2pf	1591	31	murine	murine	JJ
cord-256444-grw5s2pf	1591	32	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1591	33	JHMV	JHMV	NNP
cord-256444-grw5s2pf	1591	34	variant	variant	NN
cord-256444-grw5s2pf	1591	35	cl-2	cl-2	XX
cord-256444-grw5s2pf	1592	1	The	the	DT
cord-256444-grw5s2pf	1592	2	S2	S2	NNP
cord-256444-grw5s2pf	1592	3	subunit	subunit	NN
cord-256444-grw5s2pf	1592	4	of	of	IN
cord-256444-grw5s2pf	1592	5	the	the	DT
cord-256444-grw5s2pf	1592	6	murine	murine	JJ
cord-256444-grw5s2pf	1592	7	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1592	8	spike	spike	NN
cord-256444-grw5s2pf	1592	9	protein	protein	NN
cord-256444-grw5s2pf	1592	10	is	be	VBZ
cord-256444-grw5s2pf	1592	11	not	not	RB
cord-256444-grw5s2pf	1592	12	involved	involve	VBN
cord-256444-grw5s2pf	1592	13	in	in	IN
cord-256444-grw5s2pf	1592	14	receptor	receptor	NN
cord-256444-grw5s2pf	1592	15	binding	bind	VBG
cord-256444-grw5s2pf	1592	16	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1592	17	translational	translational	JJ
cord-256444-grw5s2pf	1592	18	regulation	regulation	NN
cord-256444-grw5s2pf	1592	19	:	:	:
cord-256444-grw5s2pf	1592	20	Leader	leader	NN
cord-256444-grw5s2pf	1592	21	affects	affect	VBZ
cord-256444-grw5s2pf	1592	22	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1592	23	efficiency	efficiency	NN
cord-256444-grw5s2pf	1593	1	Myelin	myelin	JJ
cord-256444-grw5s2pf	1593	2	basic	basic	JJ
cord-256444-grw5s2pf	1593	3	protein	protein	NN
cord-256444-grw5s2pf	1593	4	and	and	CC
cord-256444-grw5s2pf	1593	5	human	human	JJ
cord-256444-grw5s2pf	1593	6	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1593	7	2293	2293	CD
cord-256444-grw5s2pf	1593	8	cross	cross	JJ
cord-256444-grw5s2pf	1593	9	-	-	JJ
cord-256444-grw5s2pf	1593	10	reactive	reactive	JJ
cord-256444-grw5s2pf	1593	11	T	t	NN
cord-256444-grw5s2pf	1593	12	cells	cell	NNS
cord-256444-grw5s2pf	1593	13	in	in	IN
cord-256444-grw5s2pf	1593	14	multiple	multiple	JJ
cord-256444-grw5s2pf	1593	15	sclerosis	sclerosis	NN
cord-256444-grw5s2pf	1593	16	Internal	internal	JJ
cord-256444-grw5s2pf	1593	17	ribosome	ribosome	NN
cord-256444-grw5s2pf	1593	18	entry	entry	NN
cord-256444-grw5s2pf	1593	19	in	in	IN
cord-256444-grw5s2pf	1593	20	the	the	DT
cord-256444-grw5s2pf	1593	21	coding	code	VBG
cord-256444-grw5s2pf	1593	22	region	region	NN
cord-256444-grw5s2pf	1593	23	of	of	IN
cord-256444-grw5s2pf	1593	24	murine	murine	JJ
cord-256444-grw5s2pf	1593	25	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1593	26	virus	virus	NN
cord-256444-grw5s2pf	1593	27	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1594	1	5	5	LS
cord-256444-grw5s2pf	1594	2	A	a	DT
cord-256444-grw5s2pf	1594	3	region	region	NN
cord-256444-grw5s2pf	1594	4	of	of	IN
cord-256444-grw5s2pf	1594	5	the	the	DT
cord-256444-grw5s2pf	1594	6	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1594	7	infectious	infectious	JJ
cord-256444-grw5s2pf	1594	8	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1594	9	virus	virus	NN
cord-256444-grw5s2pf	1594	10	l	l	NNP
cord-256444-grw5s2pf	1594	11	a	a	DT
cord-256444-grw5s2pf	1594	12	polyprotein	polyprotein	NN
cord-256444-grw5s2pf	1594	13	encoding	encoding	NN
cord-256444-grw5s2pf	1595	1	the	the	DT
cord-256444-grw5s2pf	1595	2	3C	3c	NN
cord-256444-grw5s2pf	1595	3	-	-	HYPH
cord-256444-grw5s2pf	1595	4	like	like	JJ
cord-256444-grw5s2pf	1595	5	protease	protease	NN
cord-256444-grw5s2pf	1595	6	domain	domain	NN
cord-256444-grw5s2pf	1595	7	is	be	VBZ
cord-256444-grw5s2pf	1595	8	subject	subject	JJ
cord-256444-grw5s2pf	1595	9	to	to	IN
cord-256444-grw5s2pf	1595	10	rapid	rapid	JJ
cord-256444-grw5s2pf	1595	11	turnover	turnover	NN
cord-256444-grw5s2pf	1595	12	when	when	WRB
cord-256444-grw5s2pf	1595	13	expressed	express	VBN
cord-256444-grw5s2pf	1595	14	in	in	IN
cord-256444-grw5s2pf	1595	15	rabbit	rabbit	NN
cord-256444-grw5s2pf	1595	16	reticulocyte	reticulocyte	NNP
cord-256444-grw5s2pf	1595	17	lysate	lysate	NN
cord-256444-grw5s2pf	1595	18	Characterization	characterization	NN
cord-256444-grw5s2pf	1595	19	in	in	IN
cord-256444-grw5s2pf	1595	20	vitro	vitro	FW
cord-256444-grw5s2pf	1595	21	of	of	IN
cord-256444-grw5s2pf	1595	22	an	an	DT
cord-256444-grw5s2pf	1595	23	autocatalytic	autocatalytic	JJ
cord-256444-grw5s2pf	1595	24	processing	processing	NN
cord-256444-grw5s2pf	1595	25	activity	activity	NN
cord-256444-grw5s2pf	1595	26	associated	associate	VBN
cord-256444-grw5s2pf	1595	27	with	with	IN
cord-256444-grw5s2pf	1595	28	the	the	DT
cord-256444-grw5s2pf	1595	29	predicted	predict	VBN
cord-256444-grw5s2pf	1595	30	3C	3c	NN
cord-256444-grw5s2pf	1595	31	-	-	HYPH
cord-256444-grw5s2pf	1595	32	like	like	JJ
cord-256444-grw5s2pf	1595	33	proteinase	proteinase	NN
cord-256444-grw5s2pf	1595	34	domain	domain	NN
cord-256444-grw5s2pf	1595	35	of	of	IN
cord-256444-grw5s2pf	1595	36	the	the	DT
cord-256444-grw5s2pf	1595	37	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1595	38	avian	avian	JJ
cord-256444-grw5s2pf	1595	39	infectious	infectious	JJ
cord-256444-grw5s2pf	1595	40	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1595	41	virus	virus	NN
cord-256444-grw5s2pf	1595	42	Infection	infection	NN
cord-256444-grw5s2pf	1595	43	of	of	IN
cord-256444-grw5s2pf	1595	44	AtT20	AtT20	NNP
cord-256444-grw5s2pf	1595	45	murine	murine	JJ
cord-256444-grw5s2pf	1595	46	pituitary	pituitary	JJ
cord-256444-grw5s2pf	1595	47	tumour	tumour	NN
cord-256444-grw5s2pf	1595	48	cells	cell	NNS
cord-256444-grw5s2pf	1595	49	by	by	IN
cord-256444-grw5s2pf	1595	50	mouse	mouse	NN
cord-256444-grw5s2pf	1595	51	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1595	52	virus	virus	NN
cord-256444-grw5s2pf	1596	1	strain	strain	VB
cord-256444-grw5s2pf	1596	2	A59	A59	NNP
cord-256444-grw5s2pf	1596	3	:	:	:
cord-256444-grw5s2pf	1597	1	Virus	virus	NN
cord-256444-grw5s2pf	1597	2	budding	budding	NN
cord-256444-grw5s2pf	1597	3	is	be	VBZ
cord-256444-grw5s2pf	1597	4	restricted	restrict	VBN
cord-256444-grw5s2pf	1597	5	to	to	IN
cord-256444-grw5s2pf	1597	6	the	the	DT
cord-256444-grw5s2pf	1597	7	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1597	8	region	region	NN
cord-256444-grw5s2pf	1597	9	Replication	replication	NN
cord-256444-grw5s2pf	1597	10	of	of	IN
cord-256444-grw5s2pf	1597	11	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1597	12	MHV	mhv	NN
cord-256444-grw5s2pf	1597	13	-	-	HYPH
cord-256444-grw5s2pf	1597	14	A59	A59	NNP
cord-256444-grw5s2pf	1597	15	in	in	IN
cord-256444-grw5s2pf	1597	16	sac	sac	NN
cord-256444-grw5s2pf	1597	17	-	-	HYPH
cord-256444-grw5s2pf	1597	18	cells	cell	NNS
cord-256444-grw5s2pf	1597	19	:	:	:
cord-256444-grw5s2pf	1597	20	Determination	determination	NN
cord-256444-grw5s2pf	1597	21	of	of	IN
cord-256444-grw5s2pf	1597	22	the	the	DT
cord-256444-grw5s2pf	1597	23	first	first	JJ
cord-256444-grw5s2pf	1597	24	site	site	NN
cord-256444-grw5s2pf	1597	25	of	of	IN
cord-256444-grw5s2pf	1597	26	budding	budding	NN
cord-256444-grw5s2pf	1597	27	of	of	IN
cord-256444-grw5s2pf	1597	28	progeny	progeny	JJ
cord-256444-grw5s2pf	1597	29	virions	virion	NNS
cord-256444-grw5s2pf	1597	30	Sorting	sort	VBG
cord-256444-grw5s2pf	1597	31	of	of	IN
cord-256444-grw5s2pf	1597	32	progeny	progeny	JJ
cord-256444-grw5s2pf	1597	33	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1597	34	from	from	IN
cord-256444-grw5s2pf	1597	35	condensed	condense	VBN
cord-256444-grw5s2pf	1597	36	secretory	secretory	JJ
cord-256444-grw5s2pf	1597	37	proteins	protein	NNS
cord-256444-grw5s2pf	1597	38	at	at	IN
cord-256444-grw5s2pf	1597	39	the	the	DT
cord-256444-grw5s2pf	1597	40	exit	exit	NN
cord-256444-grw5s2pf	1597	41	from	from	IN
cord-256444-grw5s2pf	1597	42	the	the	DT
cord-256444-grw5s2pf	1597	43	trans	trans	NNP
cord-256444-grw5s2pf	1597	44	-	-	NNP
cord-256444-grw5s2pf	1597	45	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1597	46	network	network	NN
cord-256444-grw5s2pf	1597	47	of	of	IN
cord-256444-grw5s2pf	1597	48	AtT20	AtT20	NNP
cord-256444-grw5s2pf	1597	49	cells	cell	NNS
cord-256444-grw5s2pf	1597	50	Site	site	NN
cord-256444-grw5s2pf	1597	51	of	of	IN
cord-256444-grw5s2pf	1597	52	addition	addition	NN
cord-256444-grw5s2pf	1597	53	of	of	IN
cord-256444-grw5s2pf	1597	54	N	n	NN
cord-256444-grw5s2pf	1597	55	-	-	HYPH
cord-256444-grw5s2pf	1597	56	acetyl	acetyl	NN
cord-256444-grw5s2pf	1597	57	-	-	HYPH
cord-256444-grw5s2pf	1597	58	galactosamine	galactosamine	NN
cord-256444-grw5s2pf	1597	59	to	to	IN
cord-256444-grw5s2pf	1597	60	the	the	DT
cord-256444-grw5s2pf	1597	61	E	e	NN
cord-256444-grw5s2pf	1597	62	l	l	NN
cord-256444-grw5s2pf	1597	63	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1597	64	of	of	IN
cord-256444-grw5s2pf	1597	65	mouse	mouse	NNP
cord-256444-grw5s2pf	1597	66	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1597	67	virus	virus	NN
cord-256444-grw5s2pf	1597	68	-	-	:
cord-256444-grw5s2pf	1597	69	A59	A59	NNP
cord-256444-grw5s2pf	1597	70	Induction	Induction	NNP
cord-256444-grw5s2pf	1597	71	of	of	IN
cord-256444-grw5s2pf	1597	72	antibodies	antibody	NNS
cord-256444-grw5s2pf	1597	73	protecting	protect	VBG
cord-256444-grw5s2pf	1597	74	against	against	IN
cord-256444-grw5s2pf	1597	75	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1597	76	gastroenteritis	gastroenteritis	JJ
cord-256444-grw5s2pf	1597	77	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1597	78	(	(	-LRB-
cord-256444-grw5s2pf	1597	79	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1597	80	)	)	-RRB-
cord-256444-grw5s2pf	1597	81	by	by	IN
cord-256444-grw5s2pf	1597	82	recombinant	recombinant	JJ
cord-256444-grw5s2pf	1597	83	adenovirus	adenovirus	NN
cord-256444-grw5s2pf	1597	84	expressing	express	VBG
cord-256444-grw5s2pf	1597	85	TGEV	TGEV	NNP
cord-256444-grw5s2pf	1597	86	spike	spike	NN
cord-256444-grw5s2pf	1597	87	protein	protein	NN
cord-256444-grw5s2pf	1597	88	Feline	feline	JJ
cord-256444-grw5s2pf	1597	89	aminopeptidase	aminopeptidase	NN
cord-256444-grw5s2pf	1597	90	N	n	CD
cord-256444-grw5s2pf	1597	91	serves	serve	VBZ
cord-256444-grw5s2pf	1597	92	as	as	IN
cord-256444-grw5s2pf	1597	93	a	a	DT
cord-256444-grw5s2pf	1597	94	receptor	receptor	NN
cord-256444-grw5s2pf	1597	95	for	for	IN
cord-256444-grw5s2pf	1597	96	feline	feline	JJ
cord-256444-grw5s2pf	1597	97	,	,	,
cord-256444-grw5s2pf	1597	98	canine	canine	JJ
cord-256444-grw5s2pf	1597	99	,	,	,
cord-256444-grw5s2pf	1597	100	porcine	porcine	JJ
cord-256444-grw5s2pf	1597	101	,	,	,
cord-256444-grw5s2pf	1597	102	and	and	CC
cord-256444-grw5s2pf	1597	103	human	human	JJ
cord-256444-grw5s2pf	1597	104	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1597	105	in	in	IN
cord-256444-grw5s2pf	1597	106	serogroup	serogroup	NNP
cord-256444-grw5s2pf	1598	1	I	-PRON-	PRP
cord-256444-grw5s2pf	1598	2	Isolation	Isolation	NNP
cord-256444-grw5s2pf	1598	3	of	of	IN
cord-256444-grw5s2pf	1598	4	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1598	5	antigenically	antigenically	RB
cord-256444-grw5s2pf	1598	6	indistinguishable	indistinguishable	JJ
cord-256444-grw5s2pf	1598	7	from	from	IN
cord-256444-grw5s2pf	1598	8	bovine	bovine	JJ
cord-256444-grw5s2pf	1598	9	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1598	10	from	from	IN
cord-256444-grw5s2pf	1598	11	wild	wild	JJ
cord-256444-grw5s2pf	1598	12	ruminants	ruminant	NNS
cord-256444-grw5s2pf	1598	13	with	with	IN
cord-256444-grw5s2pf	1598	14	diarrhea	diarrhea	NN
cord-256444-grw5s2pf	1599	1	The	the	DT
cord-256444-grw5s2pf	1599	2	9-kDa	9-kda	CD
cord-256444-grw5s2pf	1599	3	hydrophobic	hydrophobic	JJ
cord-256444-grw5s2pf	1599	4	protein	protein	NN
cord-256444-grw5s2pf	1599	5	encoded	encode	VBN
cord-256444-grw5s2pf	1599	6	at	at	IN
cord-256444-grw5s2pf	1599	7	the	the	DT
cord-256444-grw5s2pf	1599	8	3'-end	3'-end	CD
cord-256444-grw5s2pf	1599	9	ofthe	ofthe	DT
cord-256444-grw5s2pf	1599	10	porcine	porcine	JJ
cord-256444-grw5s2pf	1599	11	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1599	12	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1599	13	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1599	14	genome	genome	NN
cord-256444-grw5s2pf	1599	15	is	be	VBZ
cord-256444-grw5s2pf	1599	16	membrane	membrane	NN
cord-256444-grw5s2pf	1599	17	-	-	HYPH
cord-256444-grw5s2pf	1599	18	associated	associate	VBN
cord-256444-grw5s2pf	1599	19	A	a	DT
cord-256444-grw5s2pf	1599	20	domain	domain	NN
cord-256444-grw5s2pf	1600	1	a	a	DT
cord-256444-grw5s2pf	1600	2	t	t	NN
cord-256444-grw5s2pf	1601	1	the	the	DT
cord-256444-grw5s2pf	1601	2	3'-end	3'-end	CD
cord-256444-grw5s2pf	1601	3	of	of	IN
cord-256444-grw5s2pf	1601	4	the	the	DT
cord-256444-grw5s2pf	1601	5	polymerase	polymerase	NN
cord-256444-grw5s2pf	1601	6	gene	gene	NN
cord-256444-grw5s2pf	1601	7	is	be	VBZ
cord-256444-grw5s2pf	1601	8	essential	essential	JJ
cord-256444-grw5s2pf	1601	9	for	for	IN
cord-256444-grw5s2pf	1601	10	encapsidation	encapsidation	NN
cord-256444-grw5s2pf	1601	11	of	of	IN
cord-256444-grw5s2pf	1601	12	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1601	13	defective	defective	JJ
cord-256444-grw5s2pf	1601	14	interfering	interfere	VBG
cord-256444-grw5s2pf	1601	15	RNAs	rna	NNS
cord-256444-grw5s2pf	1601	16	Homologous	Homologous	NNP
cord-256444-grw5s2pf	1601	17	RNA	RNA	NNP
cord-256444-grw5s2pf	1601	18	recombination	recombination	NN
cord-256444-grw5s2pf	1601	19	allows	allow	VBZ
cord-256444-grw5s2pf	1601	20	efficient	efficient	JJ
cord-256444-grw5s2pf	1601	21	introduction	introduction	NN
cord-256444-grw5s2pf	1601	22	of	of	IN
cord-256444-grw5s2pf	1601	23	site	site	NN
cord-256444-grw5s2pf	1601	24	-	-	HYPH
cord-256444-grw5s2pf	1601	25	specific	specific	JJ
cord-256444-grw5s2pf	1601	26	mutations	mutation	NNS
cord-256444-grw5s2pf	1601	27	into	into	IN
cord-256444-grw5s2pf	1601	28	the	the	DT
cord-256444-grw5s2pf	1601	29	genome	genome	NN
cord-256444-grw5s2pf	1601	30	of	of	IN
cord-256444-grw5s2pf	1601	31	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1601	32	MHV	MHV	NNP
cord-256444-grw5s2pf	1601	33	-	-	HYPH
cord-256444-grw5s2pf	1601	34	A59	A59	NNP
cord-256444-grw5s2pf	1601	35	via	via	IN
cord-256444-grw5s2pf	1601	36	synthetic	synthetic	JJ
cord-256444-grw5s2pf	1601	37	co	co	NN
cord-256444-grw5s2pf	1601	38	-	-	JJ
cord-256444-grw5s2pf	1601	39	replicating	replicating	JJ
cord-256444-grw5s2pf	1601	40	RNAs	rna	NNS
cord-256444-grw5s2pf	1601	41	Subgenomic	Subgenomic	NNP
cord-256444-grw5s2pf	1601	42	RNA	RNA	NNP
cord-256444-grw5s2pf	1601	43	synthesis	synthesis	NN
cord-256444-grw5s2pf	1601	44	directed	direct	VBN
cord-256444-grw5s2pf	1601	45	by	by	IN
cord-256444-grw5s2pf	1601	46	a	a	DT
cord-256444-grw5s2pf	1601	47	synthetic	synthetic	JJ
cord-256444-grw5s2pf	1601	48	defective	defective	JJ
cord-256444-grw5s2pf	1601	49	interfering	interfere	VBG
cord-256444-grw5s2pf	1601	50	RNA	RNA	NNP
cord-256444-grw5s2pf	1601	51	of	of	IN
cord-256444-grw5s2pf	1601	52	mouse	mouse	NNP
cord-256444-grw5s2pf	1601	53	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1601	54	virus	virus	NN
cord-256444-grw5s2pf	1601	55	:	:	:
cord-256444-grw5s2pf	1602	1	A	a	DT
cord-256444-grw5s2pf	1602	2	study	study	NN
cord-256444-grw5s2pf	1602	3	of	of	IN
cord-256444-grw5s2pf	1602	4	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1602	5	transcription	transcription	NN
cord-256444-grw5s2pf	1602	6	initiation	initiation	NN
cord-256444-grw5s2pf	1602	7	Translation	translation	NN
cord-256444-grw5s2pf	1602	8	but	but	CC
cord-256444-grw5s2pf	1602	9	not	not	RB
cord-256444-grw5s2pf	1602	10	the	the	DT
cord-256444-grw5s2pf	1602	11	encoded	encoded	JJ
cord-256444-grw5s2pf	1602	12	sequence	sequence	NN
cord-256444-grw5s2pf	1602	13	is	be	VBZ
cord-256444-grw5s2pf	1602	14	essential	essential	JJ
cord-256444-grw5s2pf	1602	15	for	for	IN
cord-256444-grw5s2pf	1602	16	the	the	DT
cord-256444-grw5s2pf	1602	17	efficient	efficient	JJ
cord-256444-grw5s2pf	1602	18	propagation	propagation	NN
cord-256444-grw5s2pf	1602	19	of	of	IN
cord-256444-grw5s2pf	1602	20	the	the	DT
cord-256444-grw5s2pf	1602	21	defective	defective	JJ
cord-256444-grw5s2pf	1602	22	interfering	interfere	VBG
cord-256444-grw5s2pf	1602	23	RNAs	rna	NNS
cord-256444-grw5s2pf	1602	24	of	of	IN
cord-256444-grw5s2pf	1602	25	the	the	DT
cord-256444-grw5s2pf	1602	26	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1602	27	mouse	mouse	NN
cord-256444-grw5s2pf	1602	28	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1602	29	virus	virus	NN
cord-256444-grw5s2pf	1602	30	Rat	Rat	NNP
cord-256444-grw5s2pf	1602	31	glial	glial	JJ
cord-256444-grw5s2pf	1602	32	C6	c6	NN
cord-256444-grw5s2pf	1602	33	cells	cell	NNS
cord-256444-grw5s2pf	1602	34	are	be	VBP
cord-256444-grw5s2pf	1602	35	defective	defective	JJ
cord-256444-grw5s2pf	1602	36	in	in	IN
cord-256444-grw5s2pf	1602	37	murine	murine	JJ
cord-256444-grw5s2pf	1602	38	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1602	39	internalization	internalization	NN
cord-256444-grw5s2pf	1602	40	Regulation	regulation	NN
cord-256444-grw5s2pf	1602	41	of	of	IN
cord-256444-grw5s2pf	1602	42	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1602	43	mRNA	mrna	NN
cord-256444-grw5s2pf	1602	44	transcription	transcription	NN
cord-256444-grw5s2pf	1602	45	Sequence	sequence	NN
cord-256444-grw5s2pf	1602	46	comparison	comparison	NN
cord-256444-grw5s2pf	1602	47	of	of	IN
cord-256444-grw5s2pf	1602	48	porcine	porcine	JJ
cord-256444-grw5s2pf	1602	49	respiratory	respiratory	JJ
cord-256444-grw5s2pf	1602	50	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1602	51	isolates	isolate	VBZ
cord-256444-grw5s2pf	1602	52	reveals	reveal	VBZ
cord-256444-grw5s2pf	1602	53	heterogeneity	heterogeneity	NN
cord-256444-grw5s2pf	1602	54	in	in	IN
cord-256444-grw5s2pf	1602	55	the	the	DT
cord-256444-grw5s2pf	1602	56	S	S	NNP
cord-256444-grw5s2pf	1602	57	Intracellular	Intracellular	NNP
cord-256444-grw5s2pf	1602	58	transport	transport	NN
cord-256444-grw5s2pf	1602	59	of	of	IN
cord-256444-grw5s2pf	1602	60	recombinant	recombinant	JJ
cord-256444-grw5s2pf	1602	61	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1602	62	spike	spike	NN
cord-256444-grw5s2pf	1602	63	proteins	protein	NNS
cord-256444-grw5s2pf	1602	64	:	:	:
cord-256444-grw5s2pf	1602	65	Implications	implication	NNS
cord-256444-grw5s2pf	1602	66	for	for	IN
cord-256444-grw5s2pf	1602	67	virus	virus	NN
cord-256444-grw5s2pf	1602	68	assembly	assembly	NN
cord-256444-grw5s2pf	1602	69	Early	early	JJ
cord-256444-grw5s2pf	1602	70	death	death	NN
cord-256444-grw5s2pf	1602	71	after	after	IN
cord-256444-grw5s2pf	1602	72	feline	feline	JJ
cord-256444-grw5s2pf	1602	73	infectious	infectious	JJ
cord-256444-grw5s2pf	1602	74	peritonitis	peritonitis	NN
cord-256444-grw5s2pf	1602	75	virus	virus	NN
cord-256444-grw5s2pf	1602	76	challenge	challenge	NN
cord-256444-grw5s2pf	1602	77	due	due	JJ
cord-256444-grw5s2pf	1602	78	to	to	IN
cord-256444-grw5s2pf	1602	79	recombinant	recombinant	JJ
cord-256444-grw5s2pf	1602	80	vaccinia	vaccinia	NN
cord-256444-grw5s2pf	1602	81	virus	virus	NN
cord-256444-grw5s2pf	1602	82	immunization	immunization	NN
cord-256444-grw5s2pf	1602	83	Primary	primary	JJ
cord-256444-grw5s2pf	1602	84	structure	structure	NN
cord-256444-grw5s2pf	1602	85	of	of	IN
cord-256444-grw5s2pf	1602	86	the	the	DT
cord-256444-grw5s2pf	1602	87	membrane	membrane	NN
cord-256444-grw5s2pf	1602	88	and	and	CC
cord-256444-grw5s2pf	1602	89	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1602	90	protein	protein	NN
cord-256444-grw5s2pf	1602	91	genes	gene	NNS
cord-256444-grw5s2pf	1602	92	of	of	IN
cord-256444-grw5s2pf	1602	93	feline	feline	JJ
cord-256444-grw5s2pf	1602	94	infectious	infectious	JJ
cord-256444-grw5s2pf	1602	95	peritonitis	peritonitis	NN
cord-256444-grw5s2pf	1602	96	virus	virus	NN
cord-256444-grw5s2pf	1602	97	and	and	CC
cord-256444-grw5s2pf	1602	98	immunogenicity	immunogenicity	NN
cord-256444-grw5s2pf	1602	99	of	of	IN
cord-256444-grw5s2pf	1602	100	recombinant	recombinant	JJ
cord-256444-grw5s2pf	1602	101	vaccinia	vaccinia	NN
cord-256444-grw5s2pf	1602	102	viruses	virus	NNS
cord-256444-grw5s2pf	1602	103	in	in	IN
cord-256444-grw5s2pf	1602	104	kittens	kitten	NNS
cord-256444-grw5s2pf	1602	105	A	a	DT
cord-256444-grw5s2pf	1602	106	novel	novel	JJ
cord-256444-grw5s2pf	1602	107	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1602	108	of	of	IN
cord-256444-grw5s2pf	1602	109	feline	feline	JJ
cord-256444-grw5s2pf	1602	110	infectious	infectious	JJ
cord-256444-grw5s2pf	1602	111	peritonitis	peritonitis	NN
cord-256444-grw5s2pf	1602	112	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1602	113	contains	contain	VBZ
cord-256444-grw5s2pf	1602	114	a	a	DT
cord-256444-grw5s2pf	1602	115	KDEL	KDEL	NNP
cord-256444-grw5s2pf	1602	116	-	-	HYPH
cord-256444-grw5s2pf	1602	117	like	like	JJ
cord-256444-grw5s2pf	1602	118	endoplasmic	endoplasmic	NN
cord-256444-grw5s2pf	1602	119	reticulum	reticulum	NN
cord-256444-grw5s2pf	1602	120	retention	retention	NN
cord-256444-grw5s2pf	1602	121	signal	signal	NN
cord-256444-grw5s2pf	1602	122	Nucleocapsid	Nucleocapsid	NNP
cord-256444-grw5s2pf	1602	123	-	-	HYPH
cord-256444-grw5s2pf	1602	124	independent	independent	JJ
cord-256444-grw5s2pf	1602	125	assembly	assembly	NN
cord-256444-grw5s2pf	1602	126	of	of	IN
cord-256444-grw5s2pf	1602	127	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1602	128	-	-	HYPH
cord-256444-grw5s2pf	1602	129	like	like	JJ
cord-256444-grw5s2pf	1602	130	particles	particle	NNS
cord-256444-grw5s2pf	1602	131	by	by	IN
cord-256444-grw5s2pf	1602	132	co	co	NN
cord-256444-grw5s2pf	1602	133	-	-	NN
cord-256444-grw5s2pf	1602	134	expression	expression	NN
cord-256444-grw5s2pf	1602	135	of	of	IN
cord-256444-grw5s2pf	1602	136	viral	viral	JJ
cord-256444-grw5s2pf	1602	137	envelope	envelope	NN
cord-256444-grw5s2pf	1602	138	protein	protein	NN
cord-256444-grw5s2pf	1602	139	genes	gene	NNS
cord-256444-grw5s2pf	1603	1	The	the	DT
cord-256444-grw5s2pf	1603	2	E3	e3	NN
cord-256444-grw5s2pf	1603	3	protein	protein	NN
cord-256444-grw5s2pf	1603	4	of	of	IN
cord-256444-grw5s2pf	1603	5	bovine	bovine	JJ
cord-256444-grw5s2pf	1603	6	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1603	7	is	be	VBZ
cord-256444-grw5s2pf	1603	8	a	a	DT
cord-256444-grw5s2pf	1603	9	receptor	receptor	NN
cord-256444-grw5s2pf	1603	10	-	-	HYPH
cord-256444-grw5s2pf	1603	11	destroying	destroy	VBG
cord-256444-grw5s2pf	1603	12	enzyme	enzyme	NN
cord-256444-grw5s2pf	1603	13	with	with	IN
cord-256444-grw5s2pf	1603	14	acetyltransferase	acetyltransferase	NNP
cord-256444-grw5s2pf	1603	15	activity	activity	NN
cord-256444-grw5s2pf	1603	16	Human	Human	NNP
cord-256444-grw5s2pf	1603	17	and	and	CC
cord-256444-grw5s2pf	1603	18	bovine	bovine	JJ
cord-256444-grw5s2pf	1603	19	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1603	20	recognize	recognize	VBP
cord-256444-grw5s2pf	1603	21	sialic	sialic	JJ
cord-256444-grw5s2pf	1603	22	acid	acid	NN
cord-256444-grw5s2pf	1603	23	-	-	HYPH
cord-256444-grw5s2pf	1603	24	containing	contain	VBG
cord-256444-grw5s2pf	1603	25	receptors	receptor	NNS
cord-256444-grw5s2pf	1603	26	similar	similar	JJ
cord-256444-grw5s2pf	1603	27	to	to	IN
cord-256444-grw5s2pf	1603	28	those	those	DT
cord-256444-grw5s2pf	1603	29	of	of	IN
cord-256444-grw5s2pf	1603	30	influenza	influenza	NN
cord-256444-grw5s2pf	1603	31	C	c	NN
cord-256444-grw5s2pf	1603	32	viruses	virus	NNS
cord-256444-grw5s2pf	1603	33	Sequence	sequence	NN
cord-256444-grw5s2pf	1603	34	analysis	analysis	NN
cord-256444-grw5s2pf	1603	35	of	of	IN
cord-256444-grw5s2pf	1603	36	the	the	DT
cord-256444-grw5s2pf	1603	37	spike	spike	NN
cord-256444-grw5s2pf	1603	38	protein	protein	NN
cord-256444-grw5s2pf	1603	39	gene	gene	NN
cord-256444-grw5s2pf	1603	40	of	of	IN
cord-256444-grw5s2pf	1603	41	murine	murine	JJ
cord-256444-grw5s2pf	1603	42	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1603	43	variants	variant	NNS
cord-256444-grw5s2pf	1603	44	:	:	:
cord-256444-grw5s2pf	1603	45	Study	study	NN
cord-256444-grw5s2pf	1603	46	of	of	IN
cord-256444-grw5s2pf	1603	47	genetic	genetic	JJ
cord-256444-grw5s2pf	1603	48	sites	site	NNS
cord-256444-grw5s2pf	1603	49	affecting	affect	VBG
cord-256444-grw5s2pf	1603	50	neuropathogenicity	neuropathogenicity	NN
cord-256444-grw5s2pf	1603	51	Evidence	evidence	NN
cord-256444-grw5s2pf	1603	52	of	of	IN
cord-256444-grw5s2pf	1603	53	natural	natural	JJ
cord-256444-grw5s2pf	1603	54	recombination	recombination	NN
cord-256444-grw5s2pf	1603	55	within	within	IN
cord-256444-grw5s2pf	1603	56	the	the	DT
cord-256444-grw5s2pf	1603	57	S1	S1	NNP
cord-256444-grw5s2pf	1603	58	gene	gene	NN
cord-256444-grw5s2pf	1603	59	of	of	IN
cord-256444-grw5s2pf	1603	60	the	the	DT
cord-256444-grw5s2pf	1603	61	infectious	infectious	JJ
cord-256444-grw5s2pf	1603	62	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1603	63	virus	virus	NN
cord-256444-grw5s2pf	1603	64	Evolutionary	evolutionary	JJ
cord-256444-grw5s2pf	1603	65	implications	implication	NNS
cord-256444-grw5s2pf	1603	66	of	of	IN
cord-256444-grw5s2pf	1603	67	genetic	genetic	JJ
cord-256444-grw5s2pf	1603	68	variations	variation	NNS
cord-256444-grw5s2pf	1603	69	in	in	IN
cord-256444-grw5s2pf	1603	70	the	the	DT
cord-256444-grw5s2pf	1603	71	S1	S1	NNP
cord-256444-grw5s2pf	1603	72	gene	gene	NN
cord-256444-grw5s2pf	1603	73	of	of	IN
cord-256444-grw5s2pf	1603	74	infectious	infectious	JJ
cord-256444-grw5s2pf	1603	75	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1603	76	virus	virus	NN
cord-256444-grw5s2pf	1603	77	Genetic	genetic	JJ
cord-256444-grw5s2pf	1603	78	variation	variation	NN
cord-256444-grw5s2pf	1603	79	of	of	IN
cord-256444-grw5s2pf	1603	80	neurotropic	neurotropic	NNP
cord-256444-grw5s2pf	1603	81	and	and	CC
cord-256444-grw5s2pf	1603	82	non	non	JJ
cord-256444-grw5s2pf	1603	83	-	-	JJ
cord-256444-grw5s2pf	1603	84	neurotropic	neurotropic	JJ
cord-256444-grw5s2pf	1603	85	murine	murine	JJ
cord-256444-grw5s2pf	1603	86	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1604	1	The	the	DT
cord-256444-grw5s2pf	1604	2	peplomer	peplomer	JJ
cord-256444-grw5s2pf	1604	3	protein	protein	NN
cord-256444-grw5s2pf	1604	4	E2	E2	NNP
cord-256444-grw5s2pf	1604	5	of	of	IN
cord-256444-grw5s2pf	1604	6	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1604	7	JHM	JHM	NNP
cord-256444-grw5s2pf	1604	8	as	as	IN
cord-256444-grw5s2pf	1604	9	a	a	DT
cord-256444-grw5s2pf	1604	10	determinant	determinant	NN
cord-256444-grw5s2pf	1604	11	of	of	IN
cord-256444-grw5s2pf	1604	12	neurovirulence	neurovirulence	NN
cord-256444-grw5s2pf	1604	13	:	:	:
cord-256444-grw5s2pf	1604	14	Definition	definition	NN
cord-256444-grw5s2pf	1604	15	of	of	IN
cord-256444-grw5s2pf	1604	16	critical	critical	JJ
cord-256444-grw5s2pf	1604	17	epitopes	epitope	NNS
cord-256444-grw5s2pf	1604	18	by	by	IN
cord-256444-grw5s2pf	1604	19	variant	variant	NN
cord-256444-grw5s2pf	1604	20	analysis	analysis	NN
cord-256444-grw5s2pf	1604	21	Evidence	evidence	NN
cord-256444-grw5s2pf	1604	22	for	for	IN
cord-256444-grw5s2pf	1604	23	a	a	DT
cord-256444-grw5s2pf	1604	24	putative	putative	JJ
cord-256444-grw5s2pf	1604	25	second	second	JJ
cord-256444-grw5s2pf	1604	26	receptor	receptor	NN
cord-256444-grw5s2pf	1604	27	for	for	IN
cord-256444-grw5s2pf	1604	28	porcine	porcine	JJ
cord-256444-grw5s2pf	1604	29	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1604	30	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1604	31	virus	virus	NN
cord-256444-grw5s2pf	1604	32	on	on	IN
cord-256444-grw5s2pf	1604	33	the	the	DT
cord-256444-grw5s2pf	1604	34	villous	villous	NNP
cord-256444-grw5s2pf	1604	35	enterocytes	enterocytes	NNPS
cord-256444-grw5s2pf	1604	36	of	of	IN
cord-256444-grw5s2pf	1604	37	newborn	newborn	JJ
cord-256444-grw5s2pf	1604	38	pigs	pig	NNS
cord-256444-grw5s2pf	1604	39	Monoclonal	monoclonal	JJ
cord-256444-grw5s2pf	1604	40	antibodies	antibody	NNS
cord-256444-grw5s2pf	1604	41	to	to	IN
cord-256444-grw5s2pf	1604	42	the	the	DT
cord-256444-grw5s2pf	1604	43	peplomer	peplomer	JJ
cord-256444-grw5s2pf	1604	44	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1604	45	of	of	IN
cord-256444-grw5s2pf	1604	46	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1604	47	mouse	mouse	NN
cord-256444-grw5s2pf	1605	1	16	16	CD
cord-256444-grw5s2pf	1605	2	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1605	3	virus	virus	NN
cord-256444-grw5s2pf	1605	4	identify	identify	VBP
cord-256444-grw5s2pf	1605	5	two	two	CD
cord-256444-grw5s2pf	1605	6	subunits	subunit	NNS
cord-256444-grw5s2pf	1605	7	and	and	CC
cord-256444-grw5s2pf	1605	8	detect	detect	VB
cord-256444-grw5s2pf	1605	9	a	a	DT
cord-256444-grw5s2pf	1605	10	conformational	conformational	JJ
cord-256444-grw5s2pf	1605	11	change	change	NN
cord-256444-grw5s2pf	1605	12	in	in	IN
cord-256444-grw5s2pf	1605	13	the	the	DT
cord-256444-grw5s2pf	1605	14	subunit	subunit	NN
cord-256444-grw5s2pf	1605	15	released	release	VBN
cord-256444-grw5s2pf	1605	16	under	under	IN
cord-256444-grw5s2pf	1605	17	mild	mild	JJ
cord-256444-grw5s2pf	1605	18	alkaline	alkaline	JJ
cord-256444-grw5s2pf	1605	19	conditions	condition	NNS
cord-256444-grw5s2pf	1605	20	The	the	DT
cord-256444-grw5s2pf	1605	21	proposed	propose	VBN
cord-256444-grw5s2pf	1605	22	family	family	NN
cord-256444-grw5s2pf	1605	23	Toroviridae	Toroviridae	NNP
cord-256444-grw5s2pf	1605	24	:	:	:
cord-256444-grw5s2pf	1605	25	agents	agent	NNS
cord-256444-grw5s2pf	1605	26	of	of	IN
cord-256444-grw5s2pf	1605	27	enteric	enteric	JJ
cord-256444-grw5s2pf	1605	28	infections	infection	NNS
cord-256444-grw5s2pf	1605	29	.	.	.
cord-256444-grw5s2pf	1606	1	Brief	brief	JJ
cord-256444-grw5s2pf	1606	2	review	review	NN
cord-256444-grw5s2pf	1606	3	Pathogenesis	Pathogenesis	NNP
cord-256444-grw5s2pf	1606	4	of	of	IN
cord-256444-grw5s2pf	1606	5	feline	feline	JJ
cord-256444-grw5s2pf	1606	6	infectious	infectious	JJ
cord-256444-grw5s2pf	1606	7	peritonitis	peritonitis	NN
cord-256444-grw5s2pf	1606	8	:	:	:
cord-256444-grw5s2pf	1606	9	nature	nature	NN
cord-256444-grw5s2pf	1606	10	and	and	CC
cord-256444-grw5s2pf	1606	11	development	development	NN
cord-256444-grw5s2pf	1606	12	of	of	IN
cord-256444-grw5s2pf	1606	13	viremia	viremia	NNP
cord-256444-grw5s2pf	1606	14	Oligomerization	Oligomerization	NNP
cord-256444-grw5s2pf	1606	15	of	of	IN
cord-256444-grw5s2pf	1606	16	a	a	DT
cord-256444-grw5s2pf	1606	17	membrane	membrane	NN
cord-256444-grw5s2pf	1606	18	protein	protein	NN
cord-256444-grw5s2pf	1606	19	correlates	correlate	VBZ
cord-256444-grw5s2pf	1606	20	with	with	IN
cord-256444-grw5s2pf	1606	21	its	-PRON-	PRP$
cord-256444-grw5s2pf	1606	22	retention	retention	NN
cord-256444-grw5s2pf	1606	23	in	in	IN
cord-256444-grw5s2pf	1606	24	the	the	DT
cord-256444-grw5s2pf	1606	25	Golgi	Golgi	NNP
cord-256444-grw5s2pf	1606	26	complex	complex	NN
cord-256444-grw5s2pf	1606	27	Natural	natural	JJ
cord-256444-grw5s2pf	1606	28	cytotoxicity	cytotoxicity	NN
cord-256444-grw5s2pf	1606	29	against	against	IN
cord-256444-grw5s2pf	1606	30	mouse	mouse	NNP
cord-256444-grw5s2pf	1606	31	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1606	32	virus	virus	NN
cord-256444-grw5s2pf	1606	33	-	-	HYPH
cord-256444-grw5s2pf	1606	34	infected	infect	VBN
cord-256444-grw5s2pf	1606	35	cells	cell	NNS
cord-256444-grw5s2pf	1606	36	.	.	.
cord-256444-grw5s2pf	1607	1	11	11	CD
cord-256444-grw5s2pf	1607	2	.	.	.
cord-256444-grw5s2pf	1608	1	A	a	DT
cord-256444-grw5s2pf	1608	2	cytotoxic	cytotoxic	JJ
cord-256444-grw5s2pf	1608	3	effector	effector	NN
cord-256444-grw5s2pf	1608	4	cell	cell	NN
cord-256444-grw5s2pf	1608	5	with	with	IN
cord-256444-grw5s2pf	1608	6	a	a	DT
cord-256444-grw5s2pf	1608	7	B	b	NN
cord-256444-grw5s2pf	1608	8	lymphocyte	lymphocyte	NN
cord-256444-grw5s2pf	1608	9	phenotype	phenotype	NN
cord-256444-grw5s2pf	1608	10	Evidence	evidence	NN
cord-256444-grw5s2pf	1608	11	for	for	IN
cord-256444-grw5s2pf	1608	12	a	a	DT
cord-256444-grw5s2pf	1608	13	porcine	porcine	JJ
cord-256444-grw5s2pf	1608	14	respiratory	respiratory	JJ
cord-256444-grw5s2pf	1608	15	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1608	16	,	,	,
cord-256444-grw5s2pf	1608	17	antigenically	antigenically	RB
cord-256444-grw5s2pf	1608	18	similar	similar	JJ
cord-256444-grw5s2pf	1608	19	to	to	IN
cord-256444-grw5s2pf	1608	20	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1608	21	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1608	22	virus	virus	NN
cord-256444-grw5s2pf	1608	23	,	,	,
cord-256444-grw5s2pf	1608	24	in	in	IN
cord-256444-grw5s2pf	1608	25	the	the	DT
cord-256444-grw5s2pf	1608	26	United	United	NNP
cord-256444-grw5s2pf	1608	27	States	States	NNP
cord-256444-grw5s2pf	1608	28	Genetic	Genetic	NNP
cord-256444-grw5s2pf	1608	29	analysis	analysis	NN
cord-256444-grw5s2pf	1608	30	of	of	IN
cord-256444-grw5s2pf	1608	31	porcine	porcine	JJ
cord-256444-grw5s2pf	1608	32	respiratory	respiratory	JJ
cord-256444-grw5s2pf	1608	33	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1608	34	,	,	,
cord-256444-grw5s2pf	1608	35	an	an	DT
cord-256444-grw5s2pf	1608	36	attenuated	attenuated	JJ
cord-256444-grw5s2pf	1608	37	variant	variant	NN
cord-256444-grw5s2pf	1608	38	of	of	IN
cord-256444-grw5s2pf	1608	39	transmissible	transmissible	JJ
cord-256444-grw5s2pf	1608	40	gastroenteritis	gastroenteritis	NN
cord-256444-grw5s2pf	1608	41	virus	virus	NN
cord-256444-grw5s2pf	1609	1	The	the	DT
cord-256444-grw5s2pf	1609	2	replication	replication	NN
cord-256444-grw5s2pf	1609	3	of	of	IN
cord-256444-grw5s2pf	1609	4	murine	murine	JJ
cord-256444-grw5s2pf	1609	5	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1609	6	in	in	IN
cord-256444-grw5s2pf	1609	7	enucleated	enucleated	JJ
cord-256444-grw5s2pf	1609	8	cells	cell	NNS
cord-256444-grw5s2pf	1609	9	Evidence	evidence	NN
cord-256444-grw5s2pf	1609	10	for	for	IN
cord-256444-grw5s2pf	1609	11	a	a	DT
cord-256444-grw5s2pf	1609	12	pseudoknot	pseudoknot	NN
cord-256444-grw5s2pf	1609	13	in	in	IN
cord-256444-grw5s2pf	1609	14	the	the	DT
cord-256444-grw5s2pf	1609	15	3'-untranslated	3'-untranslated	JJ
cord-256444-grw5s2pf	1609	16	region	region	NN
cord-256444-grw5s2pf	1609	17	of	of	IN
cord-256444-grw5s2pf	1609	18	the	the	DT
cord-256444-grw5s2pf	1609	19	bovine	bovine	JJ
cord-256444-grw5s2pf	1609	20	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1609	21	genome	genome	NN
cord-256444-grw5s2pf	1609	22	Receptor	receptor	NN
cord-256444-grw5s2pf	1609	23	for	for	IN
cord-256444-grw5s2pf	1609	24	mouse	mouse	NN
cord-256444-grw5s2pf	1609	25	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1609	26	virus	virus	NN
cord-256444-grw5s2pf	1609	27	is	be	VBZ
cord-256444-grw5s2pf	1609	28	a	a	DT
cord-256444-grw5s2pf	1609	29	member	member	NN
cord-256444-grw5s2pf	1609	30	of	of	IN
cord-256444-grw5s2pf	1609	31	the	the	DT
cord-256444-grw5s2pf	1609	32	carcinoembryonic	carcinoembryonic	NNP
cord-256444-grw5s2pf	1609	33	antigen	antigen	NNP
cord-256444-grw5s2pf	1609	34	family	family	NN
cord-256444-grw5s2pf	1609	35	of	of	IN
cord-256444-grw5s2pf	1609	36	glycoproteins	glycoprotein	NNS
cord-256444-grw5s2pf	1609	37	In	in	IN
cord-256444-grw5s2pf	1609	38	vivo	vivo	NN
cord-256444-grw5s2pf	1609	39	and	and	CC
cord-256444-grw5s2pf	1609	40	in	in	IN
cord-256444-grw5s2pf	1609	41	vitro	vitro	FW
cord-256444-grw5s2pf	1609	42	models	model	NNS
cord-256444-grw5s2pf	1609	43	of	of	IN
cord-256444-grw5s2pf	1609	44	demyelinating	demyelinate	VBG
cord-256444-grw5s2pf	1609	45	disease	disease	NN
cord-256444-grw5s2pf	1609	46	:	:	:
cord-256444-grw5s2pf	1609	47	Efficiency	efficiency	NN
cord-256444-grw5s2pf	1609	48	of	of	IN
cord-256444-grw5s2pf	1609	49	virus	virus	NN
cord-256444-grw5s2pf	1609	50	spread	spread	NN
cord-256444-grw5s2pf	1609	51	and	and	CC
cord-256444-grw5s2pf	1609	52	formation	formation	NN
cord-256444-grw5s2pf	1609	53	of	of	IN
cord-256444-grw5s2pf	1609	54	infectious	infectious	JJ
cord-256444-grw5s2pf	1609	55	centers	center	NNS
cord-256444-grw5s2pf	1609	56	among	among	IN
cord-256444-grw5s2pf	1609	57	glial	glial	JJ
cord-256444-grw5s2pf	1609	58	cells	cell	NNS
cord-256444-grw5s2pf	1609	59	is	be	VBZ
cord-256444-grw5s2pf	1609	60	genetically	genetically	RB
cord-256444-grw5s2pf	1609	61	determined	determine	VBN
cord-256444-grw5s2pf	1609	62	by	by	IN
cord-256444-grw5s2pf	1609	63	the	the	DT
cord-256444-grw5s2pf	1609	64	murine	murine	JJ
cord-256444-grw5s2pf	1609	65	host	host	NN
cord-256444-grw5s2pf	1609	66	In	in	IN
cord-256444-grw5s2pf	1609	67	vivo	vivo	NN
cord-256444-grw5s2pf	1609	68	and	and	CC
cord-256444-grw5s2pf	1609	69	in	in	IN
cord-256444-grw5s2pf	1609	70	vitro	vitro	FW
cord-256444-grw5s2pf	1609	71	models	model	NNS
cord-256444-grw5s2pf	1609	72	of	of	IN
cord-256444-grw5s2pf	1609	73	demyelinating	demyelinate	VBG
cord-256444-grw5s2pf	1609	74	disease	disease	NN
cord-256444-grw5s2pf	1609	75	.	.	.
cord-256444-grw5s2pf	1610	1	Possible	possible	JJ
cord-256444-grw5s2pf	1610	2	relationship	relationship	NN
cord-256444-grw5s2pf	1610	3	between	between	IN
cord-256444-grw5s2pf	1610	4	induction	induction	NN
cord-256444-grw5s2pf	1610	5	of	of	IN
cord-256444-grw5s2pf	1610	6	regulatory	regulatory	JJ
cord-256444-grw5s2pf	1610	7	subunit	subunit	NN
cord-256444-grw5s2pf	1610	8	from	from	IN
cord-256444-grw5s2pf	1610	9	CAMP	camp	NN
cord-256444-grw5s2pf	1610	10	dependent	dependent	JJ
cord-256444-grw5s2pf	1610	11	protein	protein	NN
cord-256444-grw5s2pf	1610	12	kinases	kinase	NNS
cord-256444-grw5s2pf	1610	13	and	and	CC
cord-256444-grw5s2pf	1610	14	inhibition	inhibition	NN
cord-256444-grw5s2pf	1610	15	of	of	IN
cord-256444-grw5s2pf	1610	16	JHMV	JHMV	NNP
cord-256444-grw5s2pf	1610	17	replication	replication	NN
cord-256444-grw5s2pf	1610	18	in	in	IN
cord-256444-grw5s2pf	1610	19	cultured	cultured	JJ
cord-256444-grw5s2pf	1610	20	oligodendrocytes	oligodendrocyte	NNS
cord-256444-grw5s2pf	1611	1	Murine	murine	JJ
cord-256444-grw5s2pf	1611	2	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1611	3	packaging	packaging	NN
cord-256444-grw5s2pf	1611	4	signal	signal	NN
cord-256444-grw5s2pf	1611	5	confers	confer	VBZ
cord-256444-grw5s2pf	1611	6	packaging	packaging	NN
cord-256444-grw5s2pf	1611	7	to	to	IN
cord-256444-grw5s2pf	1611	8	nonviral	nonviral	NNP
cord-256444-grw5s2pf	1611	9	RNA	RNA	NNP
cord-256444-grw5s2pf	1611	10	Human	Human	NNP
cord-256444-grw5s2pf	1611	11	aminopeptidase	aminopeptidase	NN
cord-256444-grw5s2pf	1611	12	N	N	NNP
cord-256444-grw5s2pf	1611	13	is	be	VBZ
cord-256444-grw5s2pf	1611	14	a	a	DT
cord-256444-grw5s2pf	1611	15	receptor	receptor	NN
cord-256444-grw5s2pf	1611	16	for	for	IN
cord-256444-grw5s2pf	1611	17	human	human	JJ
cord-256444-grw5s2pf	1611	18	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1611	19	2293	2293	CD
cord-256444-grw5s2pf	1611	20	Mouse	Mouse	NNP
cord-256444-grw5s2pf	1611	21	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1611	22	virus	virus	NN
cord-256444-grw5s2pf	1611	23	S	S	NNP
cord-256444-grw5s2pf	1611	24	RNA	RNA	NNP
cord-256444-grw5s2pf	1611	25	sequence	sequence	NN
cord-256444-grw5s2pf	1611	26	reveals	reveal	VBZ
cord-256444-grw5s2pf	1611	27	that	that	IN
cord-256444-grw5s2pf	1611	28	nonstructural	nonstructural	JJ
cord-256444-grw5s2pf	1611	29	proteins	protein	NNS
cord-256444-grw5s2pf	1611	30	NS	NS	NNP
cord-256444-grw5s2pf	1611	31	4	4	CD
cord-256444-grw5s2pf	1611	32	and	and	CC
cord-256444-grw5s2pf	1611	33	NS	NS	NNP
cord-256444-grw5s2pf	1611	34	5a	5a	CD
cord-256444-grw5s2pf	1611	35	are	be	VBP
cord-256444-grw5s2pf	1611	36	not	not	RB
cord-256444-grw5s2pf	1611	37	essential	essential	JJ
cord-256444-grw5s2pf	1611	38	for	for	IN
cord-256444-grw5s2pf	1611	39	murine	murine	JJ
cord-256444-grw5s2pf	1611	40	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1611	41	replication	replication	NN
cord-256444-grw5s2pf	1611	42	Mouse	Mouse	NNP
cord-256444-grw5s2pf	1611	43	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1611	44	virus	virus	NN
cord-256444-grw5s2pf	1611	45	utilizes	utilize	VBZ
cord-256444-grw5s2pf	1611	46	two	two	CD
cord-256444-grw5s2pf	1611	47	carcinoembryonic	carcinoembryonic	NNP
cord-256444-grw5s2pf	1611	48	antigens	antigen	NNS
cord-256444-grw5s2pf	1611	49	as	as	IN
cord-256444-grw5s2pf	1611	50	alternative	alternative	JJ
cord-256444-grw5s2pf	1611	51	receptors	receptor	NNS
cord-256444-grw5s2pf	1612	1	The	the	DT
cord-256444-grw5s2pf	1612	2	receptor	receptor	NN
cord-256444-grw5s2pf	1612	3	for	for	IN
cord-256444-grw5s2pf	1612	4	mouse	mouse	NNP
cord-256444-grw5s2pf	1612	5	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1612	6	virus	virus	NN
cord-256444-grw5s2pf	1612	7	in	in	IN
cord-256444-grw5s2pf	1612	8	the	the	DT
cord-256444-grw5s2pf	1612	9	resistant	resistant	JJ
cord-256444-grw5s2pf	1612	10	mouse	mouse	NN
cord-256444-grw5s2pf	1612	11	strain	strain	NN
cord-256444-grw5s2pf	1612	12	SJL	SJL	NNP
cord-256444-grw5s2pf	1612	13	is	be	VBZ
cord-256444-grw5s2pf	1612	14	functional	functional	JJ
cord-256444-grw5s2pf	1612	15	:	:	:
cord-256444-grw5s2pf	1612	16	Implications	implication	NNS
cord-256444-grw5s2pf	1612	17	for	for	IN
cord-256444-grw5s2pf	1612	18	the	the	DT
cord-256444-grw5s2pf	1612	19	requirement	requirement	NN
cord-256444-grw5s2pf	1612	20	of	of	IN
cord-256444-grw5s2pf	1612	21	a	a	DT
cord-256444-grw5s2pf	1612	22	second	second	JJ
cord-256444-grw5s2pf	1612	23	factor	factor	NN
cord-256444-grw5s2pf	1612	24	for	for	IN
cord-256444-grw5s2pf	1612	25	viral	viral	JJ
cord-256444-grw5s2pf	1612	26	infection	infection	NN
cord-256444-grw5s2pf	1613	1	Biosynthesis	Biosynthesis	NNP
cord-256444-grw5s2pf	1613	2	,	,	,
cord-256444-grw5s2pf	1613	3	structure	structure	NN
cord-256444-grw5s2pf	1613	4	,	,	,
cord-256444-grw5s2pf	1613	5	and	and	CC
cord-256444-grw5s2pf	1613	6	biological	biological	JJ
cord-256444-grw5s2pf	1613	7	activities	activity	NNS
cord-256444-grw5s2pf	1613	8	of	of	IN
cord-256444-grw5s2pf	1613	9	envelope	envelope	NN
cord-256444-grw5s2pf	1613	10	protein	protein	NN
cord-256444-grw5s2pf	1613	11	gp65	gp65	NNP
cord-256444-grw5s2pf	1613	12	of	of	IN
cord-256444-grw5s2pf	1613	13	murine	murine	JJ
cord-256444-grw5s2pf	1613	14	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1613	15	Heterogeneity	heterogeneity	NN
cord-256444-grw5s2pf	1613	16	of	of	IN
cord-256444-grw5s2pf	1613	17	gene	gene	NN
cord-256444-grw5s2pf	1613	18	expression	expression	NN
cord-256444-grw5s2pf	1613	19	of	of	IN
cord-256444-grw5s2pf	1613	20	hemagglutinin	hemagglutinin	NN
cord-256444-grw5s2pf	1613	21	-	-	HYPH
cord-256444-grw5s2pf	1613	22	esterase	esterase	NN
cord-256444-grw5s2pf	1613	23	(	(	-LRB-
cord-256444-grw5s2pf	1613	24	HE	he	NN
cord-256444-grw5s2pf	1613	25	)	)	-RRB-
cord-256444-grw5s2pf	1613	26	protein	protein	NN
cord-256444-grw5s2pf	1613	27	of	of	IN
cord-256444-grw5s2pf	1613	28	murine	murine	JJ
cord-256444-grw5s2pf	1613	29	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1614	1	Hemagglutininesterase	Hemagglutininesterase	NNP
cord-256444-grw5s2pf	1614	2	(	(	-LRB-
cord-256444-grw5s2pf	1615	1	HE)-specific	he)-specific	CD
cord-256444-grw5s2pf	1615	2	monoclonal	monoclonal	JJ
cord-256444-grw5s2pf	1615	3	antibodies	antibody	NNS
cord-256444-grw5s2pf	1615	4	alter	alter	VBP
cord-256444-grw5s2pf	1615	5	the	the	DT
cord-256444-grw5s2pf	1615	6	neuropathogenicity	neuropathogenicity	NN
cord-256444-grw5s2pf	1615	7	of	of	IN
cord-256444-grw5s2pf	1615	8	mouse	mouse	NNP
cord-256444-grw5s2pf	1615	9	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1615	10	virus	virus	NN
cord-256444-grw5s2pf	1615	11	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1615	12	mRNA	mrna	NN
cord-256444-grw5s2pf	1615	13	transcription	transcription	NN
cord-256444-grw5s2pf	1615	14	:	:	:
cord-256444-grw5s2pf	1615	15	UV	uv	NN
cord-256444-grw5s2pf	1615	16	light	light	JJ
cord-256444-grw5s2pf	1615	17	transcriptional	transcriptional	JJ
cord-256444-grw5s2pf	1615	18	mapping	mapping	NN
cord-256444-grw5s2pf	1615	19	studies	study	NNS
cord-256444-grw5s2pf	1615	20	suggest	suggest	VBP
cord-256444-grw5s2pf	1615	21	an	an	DT
cord-256444-grw5s2pf	1615	22	early	early	JJ
cord-256444-grw5s2pf	1615	23	requirement	requirement	NN
cord-256444-grw5s2pf	1615	24	for	for	IN
cord-256444-grw5s2pf	1615	25	a	a	DT
cord-256444-grw5s2pf	1615	26	genomiclength	genomiclength	NN
cord-256444-grw5s2pf	1615	27	template	template	NN
cord-256444-grw5s2pf	1615	28	A	a	DT
cord-256444-grw5s2pf	1615	29	spike	spike	NN
cord-256444-grw5s2pf	1615	30	proteindependent	proteindependent	NN
cord-256444-grw5s2pf	1615	31	cellular	cellular	JJ
cord-256444-grw5s2pf	1615	32	factor	factor	NN
cord-256444-grw5s2pf	1615	33	other	other	JJ
cord-256444-grw5s2pf	1615	34	than	than	IN
cord-256444-grw5s2pf	1615	35	the	the	DT
cord-256444-grw5s2pf	1615	36	viral	viral	JJ
cord-256444-grw5s2pf	1615	37	receptor	receptor	NN
cord-256444-grw5s2pf	1615	38	is	be	VBZ
cord-256444-grw5s2pf	1615	39	required	require	VBN
cord-256444-grw5s2pf	1615	40	for	for	IN
cord-256444-grw5s2pf	1615	41	mouse	mouse	NN
cord-256444-grw5s2pf	1615	42	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1615	43	virus	virus	NN
cord-256444-grw5s2pf	1615	44	entry	entry	NN
cord-256444-grw5s2pf	1615	45	Synthesis	Synthesis	NNP
cord-256444-grw5s2pf	1615	46	and	and	CC
cord-256444-grw5s2pf	1615	47	processing	processing	NN
cord-256444-grw5s2pf	1615	48	of	of	IN
cord-256444-grw5s2pf	1615	49	the	the	DT
cord-256444-grw5s2pf	1615	50	haemagglutinin	haemagglutinin	JJ
cord-256444-grw5s2pf	1615	51	-	-	HYPH
cord-256444-grw5s2pf	1615	52	esterase	esterase	NN
cord-256444-grw5s2pf	1615	53	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1615	54	of	of	IN
cord-256444-grw5s2pf	1615	55	bovine	bovine	JJ
cord-256444-grw5s2pf	1615	56	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1615	57	encoded	encode	VBN
cord-256444-grw5s2pf	1615	58	in	in	IN
cord-256444-grw5s2pf	1615	59	the	the	DT
cord-256444-grw5s2pf	1615	60	E3	E3	NNP
cord-256444-grw5s2pf	1615	61	region	region	NN
cord-256444-grw5s2pf	1615	62	of	of	IN
cord-256444-grw5s2pf	1615	63	adenovirus	adenovirus	NN
cord-256444-grw5s2pf	1616	1	The	the	DT
cord-256444-grw5s2pf	1616	2	92	92	CD
cord-256444-grw5s2pf	1616	3	subunit	subunit	NN
cord-256444-grw5s2pf	1616	4	of	of	IN
cord-256444-grw5s2pf	1616	5	the	the	DT
cord-256444-grw5s2pf	1616	6	spike	spike	NN
cord-256444-grw5s2pf	1616	7	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1616	8	of	of	IN
cord-256444-grw5s2pf	1616	9	bovine	bovine	JJ
cord-256444-grw5s2pf	1616	10	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1616	11	mediates	mediate	VBZ
cord-256444-grw5s2pf	1616	12	membrane	membrane	NN
cord-256444-grw5s2pf	1616	13	fusion	fusion	NN
cord-256444-grw5s2pf	1616	14	in	in	IN
cord-256444-grw5s2pf	1616	15	insect	insect	NN
cord-256444-grw5s2pf	1616	16	cells	cell	NNS
cord-256444-grw5s2pf	1616	17	Mouse	Mouse	NNP
cord-256444-grw5s2pf	1616	18	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1616	19	virus	virus	NN
cord-256444-grw5s2pf	1617	1	strain	strain	VB
cord-256444-grw5s2pf	1617	2	MHV	MHV	NNP
cord-256444-grw5s2pf	1617	3	-	-	HYPH
cord-256444-grw5s2pf	1617	4	S	s	NN
cord-256444-grw5s2pf	1617	5	:	:	:
cord-256444-grw5s2pf	1618	1	Formation	formation	NN
cord-256444-grw5s2pf	1618	2	of	of	IN
cord-256444-grw5s2pf	1618	3	pseudotypes	pseudotype	NNS
cord-256444-grw5s2pf	1618	4	with	with	IN
cord-256444-grw5s2pf	1618	5	a	a	DT
cord-256444-grw5s2pf	1618	6	murine	murine	JJ
cord-256444-grw5s2pf	1618	7	leukemia	leukemia	NN
cord-256444-grw5s2pf	1618	8	virus	virus	NN
cord-256444-grw5s2pf	1618	9	envelope	envelope	NN
cord-256444-grw5s2pf	1618	10	A	a	DT
cord-256444-grw5s2pf	1618	11	conserved	conserved	JJ
cord-256444-grw5s2pf	1618	12	motif	motif	NN
cord-256444-grw5s2pf	1619	1	a	a	DT
cord-256444-grw5s2pf	1619	2	t	t	NN
cord-256444-grw5s2pf	1620	1	the	the	DT
cord-256444-grw5s2pf	1620	2	3	3	CD
cord-256444-grw5s2pf	1620	3	'	'	NN
cord-256444-grw5s2pf	1620	4	end	end	NN
cord-256444-grw5s2pf	1620	5	of	of	IN
cord-256444-grw5s2pf	1620	6	mouse	mouse	NN
cord-256444-grw5s2pf	1620	7	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1620	8	virus	virus	NN
cord-256444-grw5s2pf	1620	9	genomic	genomic	NNP
cord-256444-grw5s2pf	1620	10	RNA	RNA	NNP
cord-256444-grw5s2pf	1620	11	required	require	VBN
cord-256444-grw5s2pf	1620	12	for	for	IN
cord-256444-grw5s2pf	1620	13	host	host	NN
cord-256444-grw5s2pf	1620	14	protein	protein	NN
cord-256444-grw5s2pf	1620	15	binding	binding	NN
cord-256444-grw5s2pf	1620	16	and	and	CC
cord-256444-grw5s2pf	1620	17	viral	viral	JJ
cord-256444-grw5s2pf	1620	18	RNA	RNA	NNP
cord-256444-grw5s2pf	1620	19	replication	replication	NN
cord-256444-grw5s2pf	1620	20	Specific	specific	JJ
cord-256444-grw5s2pf	1620	21	binding	binding	NN
cord-256444-grw5s2pf	1620	22	of	of	IN
cord-256444-grw5s2pf	1620	23	host	host	NN
cord-256444-grw5s2pf	1620	24	cellular	cellular	JJ
cord-256444-grw5s2pf	1620	25	proteins	protein	NNS
cord-256444-grw5s2pf	1620	26	to	to	IN
cord-256444-grw5s2pf	1620	27	multiple	multiple	JJ
cord-256444-grw5s2pf	1620	28	sites	site	NNS
cord-256444-grw5s2pf	1620	29	within	within	IN
cord-256444-grw5s2pf	1620	30	the	the	DT
cord-256444-grw5s2pf	1620	31	3'-end	3'-end	CD
cord-256444-grw5s2pf	1620	32	of	of	IN
cord-256444-grw5s2pf	1620	33	mouse	mouse	NNP
cord-256444-grw5s2pf	1620	34	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1620	35	virus	virus	NN
cord-256444-grw5s2pf	1620	36	genomic	genomic	JJ
cord-256444-grw5s2pf	1620	37	RNA	RNA	NNP
cord-256444-grw5s2pf	1620	38	Mouse	Mouse	NNP
cord-256444-grw5s2pf	1620	39	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1620	40	virus	virus	NN
cord-256444-grw5s2pf	1620	41	gene	gene	NN
cord-256444-grw5s2pf	1620	42	5b	5b	CD
cord-256444-grw5s2pf	1620	43	protein	protein	NN
cord-256444-grw5s2pf	1621	1	is	be	VBZ
cord-256444-grw5s2pf	1621	2	a	a	DT
cord-256444-grw5s2pf	1621	3	new	new	JJ
cord-256444-grw5s2pf	1621	4	virion	virion	NN
cord-256444-grw5s2pf	1621	5	envelope	envelope	NN
cord-256444-grw5s2pf	1621	6	protein	protein	NN
cord-256444-grw5s2pf	1621	7	Unusual	unusual	JJ
cord-256444-grw5s2pf	1621	8	heterogeneity	heterogeneity	NN
cord-256444-grw5s2pf	1621	9	of	of	IN
cord-256444-grw5s2pf	1621	10	leader	leader	NN
cord-256444-grw5s2pf	1621	11	-	-	HYPH
cord-256444-grw5s2pf	1621	12	mRNA	mrna	NN
cord-256444-grw5s2pf	1621	13	fusion	fusion	NN
cord-256444-grw5s2pf	1621	14	in	in	IN
cord-256444-grw5s2pf	1621	15	a	a	DT
cord-256444-grw5s2pf	1621	16	murine	murine	JJ
cord-256444-grw5s2pf	1621	17	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1621	18	:	:	:
cord-256444-grw5s2pf	1621	19	Implications	implication	NNS
cord-256444-grw5s2pf	1621	20	for	for	IN
cord-256444-grw5s2pf	1621	21	the	the	DT
cord-256444-grw5s2pf	1621	22	mechanism	mechanism	NN
cord-256444-grw5s2pf	1621	23	of	of	IN
cord-256444-grw5s2pf	1621	24	RNA	RNA	NNP
cord-256444-grw5s2pf	1621	25	transcription	transcription	NN
cord-256444-grw5s2pf	1621	26	and	and	CC
cord-256444-grw5s2pf	1621	27	recombination	recombination	NN
cord-256444-grw5s2pf	1621	28	Interactions	interaction	NNS
cord-256444-grw5s2pf	1621	29	between	between	IN
cord-256444-grw5s2pf	1621	30	the	the	DT
cord-256444-grw5s2pf	1621	31	cytoplasmic	cytoplasmic	JJ
cord-256444-grw5s2pf	1621	32	proteins	protein	NNS
cord-256444-grw5s2pf	1621	33	and	and	CC
cord-256444-grw5s2pf	1621	34	the	the	DT
cord-256444-grw5s2pf	1621	35	intergenic	intergenic	JJ
cord-256444-grw5s2pf	1621	36	(	(	-LRB-
cord-256444-grw5s2pf	1621	37	promoter	promoter	NN
cord-256444-grw5s2pf	1621	38	)	)	-RRB-
cord-256444-grw5s2pf	1621	39	sequence	sequence	NN
cord-256444-grw5s2pf	1621	40	of	of	IN
cord-256444-grw5s2pf	1621	41	mouse	mouse	NNP
cord-256444-grw5s2pf	1621	42	hepatitis	hepatitis	NNP
cord-256444-grw5s2pf	1621	43	virus	virus	NN
cord-256444-grw5s2pf	1621	44	R	r	NN
cord-256444-grw5s2pf	1621	45	N	n	NN
cord-256444-grw5s2pf	1621	46	A	a	DT
cord-256444-grw5s2pf	1621	47	Correlation	correlation	NN
cord-256444-grw5s2pf	1621	48	with	with	IN
cord-256444-grw5s2pf	1621	49	the	the	DT
cord-256444-grw5s2pf	1621	50	amounts	amount	NNS
cord-256444-grw5s2pf	1621	51	of	of	IN
cord-256444-grw5s2pf	1621	52	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1621	53	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1622	1	transcribed	transcribe	VBN
cord-256444-grw5s2pf	1623	1	A	a	DT
cord-256444-grw5s2pf	1623	2	5'-proximal	5'-proximal	CD
cord-256444-grw5s2pf	1623	3	RNA	RNA	NNP
cord-256444-grw5s2pf	1623	4	sequence	sequence	NN
cord-256444-grw5s2pf	1623	5	of	of	IN
cord-256444-grw5s2pf	1623	6	murine	murine	JJ
cord-256444-grw5s2pf	1623	7	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1623	8	as	as	IN
cord-256444-grw5s2pf	1623	9	a	a	DT
cord-256444-grw5s2pf	1623	10	potential	potential	JJ
cord-256444-grw5s2pf	1623	11	initiation	initiation	NN
cord-256444-grw5s2pf	1623	12	site	site	NN
cord-256444-grw5s2pf	1623	13	forgenomic	forgenomic	NN
cord-256444-grw5s2pf	1623	14	-	-	HYPH
cord-256444-grw5s2pf	1623	15	lengthmRNA	lengthmrna	NN
cord-256444-grw5s2pf	1623	16	transcription	transcription	NN
cord-256444-grw5s2pf	1623	17	The	the	DT
cord-256444-grw5s2pf	1623	18	hemagglutinidesterase	hemagglutinidesterase	NN
cord-256444-grw5s2pf	1623	19	glycoprotein	glycoprotein	NN
cord-256444-grw5s2pf	1623	20	of	of	IN
cord-256444-grw5s2pf	1623	21	bovine	bovine	JJ
cord-256444-grw5s2pf	1623	22	coronaviruses	coronaviruse	NNS
cord-256444-grw5s2pf	1623	23	:	:	:
cord-256444-grw5s2pf	1623	24	Sequence	sequence	NN
cord-256444-grw5s2pf	1623	25	and	and	CC
cord-256444-grw5s2pf	1623	26	functional	functional	JJ
cord-256444-grw5s2pf	1623	27	comparisons	comparison	NNS
cord-256444-grw5s2pf	1623	28	between	between	IN
cord-256444-grw5s2pf	1623	29	virulent	virulent	JJ
cord-256444-grw5s2pf	1623	30	and	and	CC
cord-256444-grw5s2pf	1623	31	avirulent	avirulent	NN
cord-256444-grw5s2pf	1623	32	strains	strain	NNS
cord-256444-grw5s2pf	1623	33	Biological	biological	JJ
cord-256444-grw5s2pf	1623	34	and	and	CC
cord-256444-grw5s2pf	1623	35	genetic	genetic	JJ
cord-256444-grw5s2pf	1623	36	characterization	characterization	NN
cord-256444-grw5s2pf	1623	37	of	of	IN
cord-256444-grw5s2pf	1623	38	a	a	DT
cord-256444-grw5s2pf	1623	39	hemagglutinating	hemagglutinate	VBG
cord-256444-grw5s2pf	1623	40	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1623	41	isolated	isolate	VBN
cord-256444-grw5s2pf	1623	42	from	from	IN
cord-256444-grw5s2pf	1623	43	a	a	DT
cord-256444-grw5s2pf	1623	44	diarrhoeic	diarrhoeic	JJ
cord-256444-grw5s2pf	1623	45	child	child	NN
cord-256444-grw5s2pf	1623	46	Coronavirus	Coronavirus	NNP
cord-256444-grw5s2pf	1623	47	leader	leader	NN
cord-256444-grw5s2pf	1623	48	RNA	RNA	NNP
cord-256444-grw5s2pf	1623	49	regulates	regulate	VBZ
cord-256444-grw5s2pf	1623	50	and	and	CC
cord-256444-grw5s2pf	1623	51	initiates	initiate	VBZ
cord-256444-grw5s2pf	1623	52	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1623	53	mRNA	mRNA	NNP
cord-256444-grw5s2pf	1623	54	transcription	transcription	NN
cord-256444-grw5s2pf	1623	55	,	,	,
cord-256444-grw5s2pf	1623	56	both	both	CC
cord-256444-grw5s2pf	1623	57	in	in	IN
cord-256444-grw5s2pf	1623	58	trans	trans	NNP
cord-256444-grw5s2pf	1623	59	and	and	CC
cord-256444-grw5s2pf	1623	60	in	in	IN
cord-256444-grw5s2pf	1623	61	cis	cis	NNP
cord-256444-grw5s2pf	1623	62	Presence	Presence	NNP
cord-256444-grw5s2pf	1623	63	of	of	IN
cord-256444-grw5s2pf	1623	64	subgenomic	subgenomic	NNP
cord-256444-grw5s2pf	1623	65	mRNAs	mRNAs	NNPS
cord-256444-grw5s2pf	1623	66	in	in	IN
cord-256444-grw5s2pf	1623	67	virions	virion	NNS
cord-256444-grw5s2pf	1623	68	of	of	IN
cord-256444-grw5s2pf	1623	69	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1623	70	IBV	IBV	NNP
cord-256444-grw5s2pf	1624	1	The	the	DT
cord-256444-grw5s2pf	1624	2	infectious	infectious	JJ
cord-256444-grw5s2pf	1624	3	bronchitis	bronchitis	NN
cord-256444-grw5s2pf	1624	4	virus	virus	NN
cord-256444-grw5s2pf	1624	5	nucleocapsid	nucleocapsid	NN
cord-256444-grw5s2pf	1624	6	protein	protein	NN
cord-256444-grw5s2pf	1624	7	binds	bind	VBZ
cord-256444-grw5s2pf	1624	8	RNA	RNA	NNP
cord-256444-grw5s2pf	1624	9	sequences	sequence	NNS
cord-256444-grw5s2pf	1624	10	in	in	IN
cord-256444-grw5s2pf	1624	11	the	the	DT
cord-256444-grw5s2pf	1624	12	3	3	CD
cord-256444-grw5s2pf	1624	13	'	'	NN
cord-256444-grw5s2pf	1624	14	terminus	terminus	NN
cord-256444-grw5s2pf	1624	15	of	of	IN
cord-256444-grw5s2pf	1624	16	the	the	DT
cord-256444-grw5s2pf	1624	17	genome	genome	NN
cord-256444-grw5s2pf	1624	18	Characterization	characterization	NN
cord-256444-grw5s2pf	1624	19	of	of	IN
cord-256444-grw5s2pf	1624	20	a	a	DT
cord-256444-grw5s2pf	1624	21	human	human	JJ
cord-256444-grw5s2pf	1624	22	coronavirus	coronavirus	NN
cord-256444-grw5s2pf	1624	23	(	(	-LRB-
cord-256444-grw5s2pf	1624	24	strain	strain	NN
cord-256444-grw5s2pf	1624	25	2293	2293	CD
cord-256444-grw5s2pf	1624	26	)	)	-RRB-
cord-256444-grw5s2pf	1625	1	3C	3C	NNP
cord-256444-grw5s2pf	1625	2	-	-	HYPH
cord-256444-grw5s2pf	1625	3	like	like	JJ
cord-256444-grw5s2pf	1625	4	proteinase	proteinase	NN
cord-256444-grw5s2pf	1625	5	activity	activity	NN
cord-256444-grw5s2pf	1625	6	Mouse	Mouse	NNP
cord-256444-grw5s2pf	1625	7	hepatitis	hepatitis	NN
cord-256444-grw5s2pf	1625	8	virus	virus	NN
cord-256444-grw5s2pf	1625	9	ORF	ORF	NNP
cord-256444-grw5s2pf	1625	10	2a	2a	CD
cord-256444-grw5s2pf	1625	11	is	be	VBZ
cord-256444-grw5s2pf	1625	12	expressed	express	VBN
cord-256444-grw5s2pf	1625	13	in	in	IN
cord-256444-grw5s2pf	1625	14	the	the	DT
cord-256444-grw5s2pf	1625	15	cytosol	cytosol	NN
cord-256444-grw5s2pf	1625	16	of	of	IN
cord-256444-grw5s2pf	1625	17	infected	infected	JJ
cord-256444-grw5s2pf	1625	18	mouse	mouse	NN
cord-256444-grw5s2pf	1625	19	fibroblasts	fibroblast	NNS
cord-256444-grw5s2pf	1625	20	We	-PRON-	PRP
cord-256444-grw5s2pf	1625	21	would	would	MD
cord-256444-grw5s2pf	1625	22	like	like	VB
cord-256444-grw5s2pf	1625	23	to	to	TO
cord-256444-grw5s2pf	1625	24	thank	thank	VB
cord-256444-grw5s2pf	1625	25	the	the	DT
cord-256444-grw5s2pf	1625	26	following	follow	VBG
cord-256444-grw5s2pf	1625	27	individuals	individual	NNS
cord-256444-grw5s2pf	1625	28	for	for	IN
cord-256444-grw5s2pf	1625	29	making	make	VBG
cord-256444-grw5s2pf	1625	30	data	datum	NNS
cord-256444-grw5s2pf	1625	31	available	available	JJ
cord-256444-grw5s2pf	1625	32	prior	prior	RB
cord-256444-grw5s2pf	1625	33	to	to	IN
cord-256444-grw5s2pf	1625	34	publication	publication	NN
cord-256444-grw5s2pf	1625	35	:	:	:
cord-256444-grw5s2pf	1625	36	Luis	Luis	NNP
cord-256444-grw5s2pf	1625	37	Enjuanes	Enjuanes	NNP
cord-256444-grw5s2pf	1625	38	,	,	,
cord-256444-grw5s2pf	1625	39	Hubert	Hubert	NNP
cord-256444-grw5s2pf	1625	40	Laude	Laude	NNP
cord-256444-grw5s2pf	1625	41	,	,	,
cord-256444-grw5s2pf	1625	42	Peter	Peter	NNP
cord-256444-grw5s2pf	1625	43	Rottier	Rottier	NNP
cord-256444-grw5s2pf	1625	44	,	,	,
cord-256444-grw5s2pf	1625	45	and	and	CC
cord-256444-grw5s2pf	1625	46	Pierre	Pierre	NNP
cord-256444-grw5s2pf	1625	47	Talbot	Talbot	NNP
cord-256444-grw5s2pf	1625	48	.	.	.
cord-256444-grw5s2pf	1626	1	We	-PRON-	PRP
cord-256444-grw5s2pf	1626	2	would	would	MD
cord-256444-grw5s2pf	1626	3	also	also	RB
cord-256444-grw5s2pf	1626	4	like	like	VB
cord-256444-grw5s2pf	1626	5	to	to	TO
cord-256444-grw5s2pf	1626	6	thank	thank	VB
cord-256444-grw5s2pf	1626	7	Daphne	Daphne	NNP
cord-256444-grw5s2pf	1626	8	Shimoda	Shimoda	NNP
cord-256444-grw5s2pf	1626	9	for	for	IN
cord-256444-grw5s2pf	1626	10	her	-PRON-	PRP$
cord-256444-grw5s2pf	1626	11	tremendous	tremendous	JJ
cord-256444-grw5s2pf	1626	12	help	help	NN
cord-256444-grw5s2pf	1626	13	with	with	IN
cord-256444-grw5s2pf	1626	14	editorial	editorial	JJ
cord-256444-grw5s2pf	1626	15	revisions	revision	NNS
cord-256444-grw5s2pf	1626	16	,	,	,
cord-256444-grw5s2pf	1626	17	preparation	preparation	NN
cord-256444-grw5s2pf	1626	18	of	of	IN
cord-256444-grw5s2pf	1626	19	the	the	DT
cord-256444-grw5s2pf	1626	20	figures	figure	NNS
cord-256444-grw5s2pf	1626	21	,	,	,
cord-256444-grw5s2pf	1626	22	and	and	CC
cord-256444-grw5s2pf	1626	23	the	the	DT
cord-256444-grw5s2pf	1626	24	typing	typing	NN
cord-256444-grw5s2pf	1626	25	of	of	IN
cord-256444-grw5s2pf	1626	26	the	the	DT
cord-256444-grw5s2pf	1626	27	manuscript	manuscript	NN
cord-256444-grw5s2pf	1626	28	.	.	.
cord-256444-grw5s2pf	1627	1	M.M.C.L.	M.M.C.L.	NNP
cord-256444-grw5s2pf	1627	2	is	be	VBZ
cord-256444-grw5s2pf	1627	3	Investigator	Investigator	NNP
cord-256444-grw5s2pf	1627	4	of	of	IN
cord-256444-grw5s2pf	1627	5	the	the	DT
cord-256444-grw5s2pf	1627	6	Howard	Howard	NNP
cord-256444-grw5s2pf	1627	7	Hughes	Hughes	NNP
cord-256444-grw5s2pf	1627	8	Medical	Medical	NNP
cord-256444-grw5s2pf	1627	9	Institute	Institute	NNP
cord-256444-grw5s2pf	1627	10	.	.	.