id author title date pages extension mime words sentences flesch summary cache txt cord-344683-lr1xr2um Cabler, Stephanie A Cytokine Circus with a Viral Ringleader: SARS-CoV-2-Associated Cytokine Storm Syndromes 2020-09-30 .txt text/plain 2082 116 45 An unbridled host immune response to SARS-CoV-2 infection likely underlies severe cases of the disease and has been labeled a "Cytokine Storm Syndrome". Infection with SARS-CoV-2, the etiologic agent of Coronavirus Disease 2019 (COVID19) , can lead to severe pneumonia, multi-organ failure, and death. Given the clinical and laboratory features, it is reasonable to consider MIS-C as a separate but related entity to the severe multi-organ dysfunction observed in patients with S-CSS (Figure 1 ). A second study showed pediatric patients with MIS-C exhibit distinct cytokine profiles from those with severe SARS-CoV-2 respiratory disease, exhibiting higher IL-10 and TNF [19] . What are the optimal clinical characteristics and biomarkers to identify and classify cases of MIS-C, S-CSS, and other diseases associated with Cytokine Storm Syndrome? Factors associated with death outcome in patients with severe coronavirus disease-19 (COVID-19): a case-control study Multisystem inflammatory syndrome in children and COVID-19 are distinct presentations of SARS-CoV-2 ./cache/cord-344683-lr1xr2um.txt ./txt/cord-344683-lr1xr2um.txt