id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-313279-15wii9nn	Trevijano-Contador, Nuria	Expanding the use of alternative models to investigate novel aspects of immunity to microbial pathogens	2014-05-15		.txt	text/plain	2122	107	38	In the present issue of Virulence, an article entitled "The maternal transfer of bacteria can mediate trans-generational immune priming in insects" 1 describes an elegant study that illustrates the use of the lepidopteran Galleria mellonella to investigate a specific aspect of immunity to microbes. But in addition, this study opens the scope on the use of non-conventional models and illustrates how they can be used to investigate aspects of immunity against pathogenic microorganisms. These models have been a useful tool for centuries, and the development of their genetic manipulation offers new alternatives to investigate the role of specific factors of the immune system in the defense against pathogens. Among insects, there are two species largely used as model hosts to study microbial virulence, Drosophila melanogaster and Galleria mellonella. melanogaster also a suitable model to investigate the role of host elements in the response against microbial pathogens.	./cache/cord-313279-15wii9nn.txt	./txt/cord-313279-15wii9nn.txt