id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-350870-a89zj5mh	Ikeda, Hiroki	Improving the estimation of the death rate of infected cells from time course data during the acute phase of virus infections: application to acute HIV-1 infection in a humanized mouse model	2014-05-21		.txt	text/plain	5059	261	54	Both models describe the acute phase of HIV-1 infected humanized mice reasonably well, and we estimated an average death rate of infected cells of 0.61 and 0.61, an average exponential growth rate of 0.69 and 0.76, and an average basic reproduction number of 2.30 and 2.38 in the RQS model and the PWR model, respectively. To estimate the accuracy of the parameters estimated by our two novel models, we created simulated time course data of target cell densities and viral load during the acute phase of viral infection (lasting approximately 21 days [14] [15] [16] [17] [18] [19] [20] [26] [27] [28] ) assuming biologically plausible parameter values. We created artificial data with target cell densities and virus loads during acute infection using the reduced standard model for viral infection (i.e., Eqs.	./cache/cord-350870-a89zj5mh.txt	./txt/cord-350870-a89zj5mh.txt