id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-325296-zrvykzof	Zuhorn, Frédéric	Parainfectious encephalitis in COVID-19: “The Claustrum Sign”	2020-09-03		.txt	text/plain	892	58	33	Follow-up has been carried out four months later showing a normalization in cell count of CSF and improvement of MRI findings, although the claustrum lesions persisted. While immunological markers remained unspecific and imaging findings of acute necrotizing encephalitis were absent in our patient, brain MRI disclosed a unique pattern, a.k.a. the claustrum sign. Common MRI findings in a recent study of COVID-19 encephalopathy were cortical signal abnormalities on FLAIR images (37%), accompanied by diffusion reduction, leptomeningeal enhancement and cortical blooming artifacts in some cases. MRI findings in COVID-19 encephalitis, especially when suggesting autoimmune encephalopathy may imply therapeutic interventions, such as immunosuppressive therapy. Recently, progressive clinical improvement along with a reduction of inflammatory CSF parameters has been observed in COVID-19 encephalitis, following high-dose steroid treatment [11] . In summary, a previously undescribed imaging pattern in parainfectious COVID-19 encephalitis is presented that bears a strong resemblance to MRI findings in autoimmune encephalitic syndromes, such as known from epileptic or encephalitis caused by antineuronal antibodies.	./cache/cord-325296-zrvykzof.txt	./txt/cord-325296-zrvykzof.txt