id author title date pages extension mime words sentences flesch summary cache txt cord-259634-ays40jlz Marcelino, Jose Critical paths in a metapopulation model of H1N1: Efficiently delaying influenza spreading through flight cancellation 2012-05-15 .txt text/plain 4225 213 50 Here we expand on this finding further by considering a range of centrality measures for individual connections between cities, show that their targeted removal can improve on existing control strategies [5] for controlling influenza spreading and finally discuss the effect of the community structure on this control. To demonstrate the impact on influenza spreading caused by topological changes to the airline network, we run simulations using a stochastic metapopulation model of influenza [22] [23] where the worldwide network of commercial flights is used as the path for infected individuals traveling between cities (see Fig. 1A with Mexico City as starting node of an outbreak). Applying the same spreading simulations on these rewired versions of the network showed that only on networks that preserved the original's community structure did we observe a significant reduction in infections when removing edges (see Fig. 3 ) connecting nodes ranked by Jaccard coefficient. ./cache/cord-259634-ays40jlz.txt ./txt/cord-259634-ays40jlz.txt