id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-285647-9tegcrc3	Estrada, Ernesto	Fractional diffusion on the human proteome as an alternative to the multi-organ damage of SARS-CoV-2	2020-08-17		.txt	text/plain	9179	533	59	By following the main subdiffusive routes across the PPI network, we identify proteins mainly expressed in the heart, cerebral cortex, thymus, testis, lymph node, kidney, among others of the organs reported to be affected by COVID-19. 25, 26 Therefore, we assume here that perturbations produced by SARS-CoV-2 proteins on the human PPI network are propagated by means of diffusive processes. Here, we propose the use of a time-fractional diffusion model on the PPI network of proteins targeted by SARS-CoV-2. We now consider how a perturbation produced by SARS-CoV-2 on a protein mainly expressed in the lungs can be propagated to proteins mainly located in other tissues (see Table S4 in the supplementary material) by a subdiffusive process. Here, we have studied the particular case in which the time-fractional diffusion equation produces a subdiffusive regime, with the use of α = 3/4 in the network of human proteins targeted by SARS-CoV-2.	./cache/cord-285647-9tegcrc3.txt	./txt/cord-285647-9tegcrc3.txt