id sid tid token lemma pos cord-285647-9tegcrc3 1 1 key key JJ cord-285647-9tegcrc3 1 2 : : : cord-285647-9tegcrc3 1 3 cord-285647 cord-285647 NNP cord-285647-9tegcrc3 1 4 - - HYPH cord-285647-9tegcrc3 1 5 9tegcrc3 9tegcrc3 CD cord-285647-9tegcrc3 1 6 authors author NNS cord-285647-9tegcrc3 1 7 : : : cord-285647-9tegcrc3 1 8 Estrada Estrada NNP cord-285647-9tegcrc3 1 9 , , , cord-285647-9tegcrc3 1 10 Ernesto Ernesto NNP cord-285647-9tegcrc3 1 11 title title NN cord-285647-9tegcrc3 1 12 : : : cord-285647-9tegcrc3 1 13 Fractional fractional JJ cord-285647-9tegcrc3 1 14 diffusion diffusion NN cord-285647-9tegcrc3 1 15 on on IN cord-285647-9tegcrc3 1 16 the the DT cord-285647-9tegcrc3 1 17 human human JJ cord-285647-9tegcrc3 1 18 proteome proteome NN cord-285647-9tegcrc3 1 19 as as IN cord-285647-9tegcrc3 1 20 an an DT cord-285647-9tegcrc3 1 21 alternative alternative NN cord-285647-9tegcrc3 1 22 to to IN cord-285647-9tegcrc3 1 23 the the DT cord-285647-9tegcrc3 1 24 multi multi JJ cord-285647-9tegcrc3 1 25 - - JJ cord-285647-9tegcrc3 1 26 organ organ JJ cord-285647-9tegcrc3 1 27 damage damage NN cord-285647-9tegcrc3 1 28 of of IN cord-285647-9tegcrc3 1 29 SARS SARS NNP cord-285647-9tegcrc3 1 30 - - HYPH cord-285647-9tegcrc3 1 31 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 1 32 date date NN cord-285647-9tegcrc3 1 33 : : : cord-285647-9tegcrc3 1 34 2020 2020 CD cord-285647-9tegcrc3 1 35 - - HYPH cord-285647-9tegcrc3 1 36 08 08 CD cord-285647-9tegcrc3 1 37 - - SYM cord-285647-9tegcrc3 1 38 17 17 CD cord-285647-9tegcrc3 1 39 journal journal NN cord-285647-9tegcrc3 1 40 : : : cord-285647-9tegcrc3 2 1 Chaos chaos NN cord-285647-9tegcrc3 2 2 DOI doi NN cord-285647-9tegcrc3 2 3 : : : cord-285647-9tegcrc3 3 1 10.1063/5.0015626 10.1063/5.0015626 CD cord-285647-9tegcrc3 3 2 sha sha NNP cord-285647-9tegcrc3 3 3 : : : cord-285647-9tegcrc3 3 4 5bcfc438ede47fe7503811ba38ad2e579be1986e 5bcfc438ede47fe7503811ba38ad2e579be1986e CD cord-285647-9tegcrc3 3 5 doc_id doc_id CD cord-285647-9tegcrc3 3 6 : : : cord-285647-9tegcrc3 3 7 285647 285647 CD cord-285647-9tegcrc3 3 8 cord_uid cord_uid NNS cord-285647-9tegcrc3 3 9 : : : cord-285647-9tegcrc3 3 10 9tegcrc3 9tegcrc3 CD cord-285647-9tegcrc3 4 1 The the DT cord-285647-9tegcrc3 4 2 coronavirus coronavirus NN cord-285647-9tegcrc3 4 3 2019 2019 CD cord-285647-9tegcrc3 4 4 ( ( -LRB- cord-285647-9tegcrc3 4 5 COVID-19 covid-19 VB cord-285647-9tegcrc3 4 6 ) ) -RRB- cord-285647-9tegcrc3 4 7 respiratory respiratory JJ cord-285647-9tegcrc3 4 8 disease disease NN cord-285647-9tegcrc3 4 9 is be VBZ cord-285647-9tegcrc3 4 10 caused cause VBN cord-285647-9tegcrc3 4 11 by by IN cord-285647-9tegcrc3 4 12 the the DT cord-285647-9tegcrc3 4 13 novel novel JJ cord-285647-9tegcrc3 4 14 coronavirus coronavirus NN cord-285647-9tegcrc3 4 15 SARS SARS NNP cord-285647-9tegcrc3 4 16 - - HYPH cord-285647-9tegcrc3 4 17 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 4 18 ( ( -LRB- cord-285647-9tegcrc3 4 19 severe severe JJ cord-285647-9tegcrc3 4 20 acute acute JJ cord-285647-9tegcrc3 4 21 respiratory respiratory JJ cord-285647-9tegcrc3 4 22 syndrome syndrome NN cord-285647-9tegcrc3 4 23 coronavirus coronavirus NN cord-285647-9tegcrc3 4 24 2 2 CD cord-285647-9tegcrc3 4 25 ) ) -RRB- cord-285647-9tegcrc3 4 26 , , , cord-285647-9tegcrc3 4 27 which which WDT cord-285647-9tegcrc3 4 28 uses use VBZ cord-285647-9tegcrc3 4 29 the the DT cord-285647-9tegcrc3 4 30 enzyme enzyme NN cord-285647-9tegcrc3 4 31 ACE2 ACE2 NNP cord-285647-9tegcrc3 4 32 to to TO cord-285647-9tegcrc3 4 33 enter enter VB cord-285647-9tegcrc3 4 34 human human JJ cord-285647-9tegcrc3 4 35 cells cell NNS cord-285647-9tegcrc3 4 36 . . . cord-285647-9tegcrc3 5 1 This this DT cord-285647-9tegcrc3 5 2 disease disease NN cord-285647-9tegcrc3 5 3 is be VBZ cord-285647-9tegcrc3 5 4 characterized characterize VBN cord-285647-9tegcrc3 5 5 by by IN cord-285647-9tegcrc3 5 6 important important JJ cord-285647-9tegcrc3 5 7 damage damage NN cord-285647-9tegcrc3 5 8 at at IN cord-285647-9tegcrc3 5 9 a a DT cord-285647-9tegcrc3 5 10 multi multi JJ cord-285647-9tegcrc3 5 11 - - JJ cord-285647-9tegcrc3 5 12 organ organ JJ cord-285647-9tegcrc3 5 13 level level NN cord-285647-9tegcrc3 5 14 , , , cord-285647-9tegcrc3 5 15 partially partially RB cord-285647-9tegcrc3 5 16 due due JJ cord-285647-9tegcrc3 5 17 to to IN cord-285647-9tegcrc3 5 18 the the DT cord-285647-9tegcrc3 5 19 abundant abundant JJ cord-285647-9tegcrc3 5 20 expression expression NN cord-285647-9tegcrc3 5 21 of of IN cord-285647-9tegcrc3 5 22 ACE2 ACE2 NNP cord-285647-9tegcrc3 5 23 in in IN cord-285647-9tegcrc3 5 24 practically practically RB cord-285647-9tegcrc3 5 25 all all DT cord-285647-9tegcrc3 5 26 human human JJ cord-285647-9tegcrc3 5 27 tissues tissue NNS cord-285647-9tegcrc3 5 28 . . . cord-285647-9tegcrc3 6 1 However however RB cord-285647-9tegcrc3 6 2 , , , cord-285647-9tegcrc3 6 3 not not RB cord-285647-9tegcrc3 6 4 every every DT cord-285647-9tegcrc3 6 5 organ organ NN cord-285647-9tegcrc3 6 6 in in IN cord-285647-9tegcrc3 6 7 which which WDT cord-285647-9tegcrc3 6 8 ACE2 ACE2 NNP cord-285647-9tegcrc3 6 9 is be VBZ cord-285647-9tegcrc3 6 10 abundant abundant JJ cord-285647-9tegcrc3 6 11 is be VBZ cord-285647-9tegcrc3 6 12 affected affect VBN cord-285647-9tegcrc3 6 13 by by IN cord-285647-9tegcrc3 6 14 SARS SARS NNP cord-285647-9tegcrc3 6 15 - - HYPH cord-285647-9tegcrc3 6 16 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 6 17 , , , cord-285647-9tegcrc3 6 18 which which WDT cord-285647-9tegcrc3 6 19 suggests suggest VBZ cord-285647-9tegcrc3 6 20 the the DT cord-285647-9tegcrc3 6 21 existence existence NN cord-285647-9tegcrc3 6 22 of of IN cord-285647-9tegcrc3 6 23 other other JJ cord-285647-9tegcrc3 6 24 multi multi JJ cord-285647-9tegcrc3 6 25 - - JJ cord-285647-9tegcrc3 6 26 organ organ JJ cord-285647-9tegcrc3 6 27 routes route NNS cord-285647-9tegcrc3 6 28 for for IN cord-285647-9tegcrc3 6 29 transmitting transmit VBG cord-285647-9tegcrc3 6 30 the the DT cord-285647-9tegcrc3 6 31 perturbations perturbation NNS cord-285647-9tegcrc3 6 32 produced produce VBN cord-285647-9tegcrc3 6 33 by by IN cord-285647-9tegcrc3 6 34 the the DT cord-285647-9tegcrc3 6 35 virus virus NN cord-285647-9tegcrc3 6 36 . . . cord-285647-9tegcrc3 7 1 We -PRON- PRP cord-285647-9tegcrc3 7 2 consider consider VBP cord-285647-9tegcrc3 7 3 here here RB cord-285647-9tegcrc3 7 4 diffusive diffusive JJ cord-285647-9tegcrc3 7 5 processes process NNS cord-285647-9tegcrc3 7 6 through through IN cord-285647-9tegcrc3 7 7 the the DT cord-285647-9tegcrc3 7 8 protein protein NN cord-285647-9tegcrc3 7 9 – – : cord-285647-9tegcrc3 7 10 protein protein NN cord-285647-9tegcrc3 7 11 interaction interaction NN cord-285647-9tegcrc3 7 12 ( ( -LRB- cord-285647-9tegcrc3 7 13 PPI PPI NNP cord-285647-9tegcrc3 7 14 ) ) -RRB- cord-285647-9tegcrc3 7 15 network network NN cord-285647-9tegcrc3 7 16 of of IN cord-285647-9tegcrc3 7 17 proteins protein NNS cord-285647-9tegcrc3 7 18 targeted target VBN cord-285647-9tegcrc3 7 19 by by IN cord-285647-9tegcrc3 7 20 SARS SARS NNP cord-285647-9tegcrc3 7 21 - - HYPH cord-285647-9tegcrc3 7 22 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 7 23 as as IN cord-285647-9tegcrc3 7 24 an an DT cord-285647-9tegcrc3 7 25 alternative alternative JJ cord-285647-9tegcrc3 7 26 route route NN cord-285647-9tegcrc3 7 27 . . . cord-285647-9tegcrc3 8 1 We -PRON- PRP cord-285647-9tegcrc3 8 2 found find VBD cord-285647-9tegcrc3 8 3 a a DT cord-285647-9tegcrc3 8 4 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 8 5 regime regime NN cord-285647-9tegcrc3 8 6 that that WDT cord-285647-9tegcrc3 8 7 allows allow VBZ cord-285647-9tegcrc3 8 8 the the DT cord-285647-9tegcrc3 8 9 propagation propagation NN cord-285647-9tegcrc3 8 10 of of IN cord-285647-9tegcrc3 8 11 virus virus NN cord-285647-9tegcrc3 8 12 perturbations perturbation NNS cord-285647-9tegcrc3 8 13 through through IN cord-285647-9tegcrc3 8 14 the the DT cord-285647-9tegcrc3 8 15 PPI PPI NNP cord-285647-9tegcrc3 8 16 network network NN cord-285647-9tegcrc3 8 17 at at IN cord-285647-9tegcrc3 8 18 a a DT cord-285647-9tegcrc3 8 19 significant significant JJ cord-285647-9tegcrc3 8 20 rate rate NN cord-285647-9tegcrc3 8 21 . . . cord-285647-9tegcrc3 9 1 By by IN cord-285647-9tegcrc3 9 2 following follow VBG cord-285647-9tegcrc3 9 3 the the DT cord-285647-9tegcrc3 9 4 main main JJ cord-285647-9tegcrc3 9 5 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 9 6 routes route NNS cord-285647-9tegcrc3 9 7 across across IN cord-285647-9tegcrc3 9 8 the the DT cord-285647-9tegcrc3 9 9 PPI PPI NNP cord-285647-9tegcrc3 9 10 network network NN cord-285647-9tegcrc3 9 11 , , , cord-285647-9tegcrc3 9 12 we -PRON- PRP cord-285647-9tegcrc3 9 13 identify identify VBP cord-285647-9tegcrc3 9 14 proteins protein NNS cord-285647-9tegcrc3 9 15 mainly mainly RB cord-285647-9tegcrc3 9 16 expressed express VBN cord-285647-9tegcrc3 9 17 in in IN cord-285647-9tegcrc3 9 18 the the DT cord-285647-9tegcrc3 9 19 heart heart NN cord-285647-9tegcrc3 9 20 , , , cord-285647-9tegcrc3 9 21 cerebral cerebral JJ cord-285647-9tegcrc3 9 22 cortex cortex NN cord-285647-9tegcrc3 9 23 , , , cord-285647-9tegcrc3 9 24 thymus thymus NN cord-285647-9tegcrc3 9 25 , , , cord-285647-9tegcrc3 9 26 testis testis NN cord-285647-9tegcrc3 9 27 , , , cord-285647-9tegcrc3 9 28 lymph lymph NN cord-285647-9tegcrc3 9 29 node node NN cord-285647-9tegcrc3 9 30 , , , cord-285647-9tegcrc3 9 31 kidney kidney NN cord-285647-9tegcrc3 9 32 , , , cord-285647-9tegcrc3 9 33 among among IN cord-285647-9tegcrc3 9 34 others other NNS cord-285647-9tegcrc3 9 35 of of IN cord-285647-9tegcrc3 9 36 the the DT cord-285647-9tegcrc3 9 37 organs organ NNS cord-285647-9tegcrc3 9 38 reported report VBN cord-285647-9tegcrc3 9 39 to to TO cord-285647-9tegcrc3 9 40 be be VB cord-285647-9tegcrc3 9 41 affected affect VBN cord-285647-9tegcrc3 9 42 by by IN cord-285647-9tegcrc3 9 43 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 9 44 . . . cord-285647-9tegcrc3 10 1 scitation.org/journal/cha scitation.org/journal/cha PRP$ cord-285647-9tegcrc3 10 2 hypothesized hypothesize VBD cord-285647-9tegcrc3 10 3 as as IN cord-285647-9tegcrc3 10 4 a a DT cord-285647-9tegcrc3 10 5 potential potential JJ cord-285647-9tegcrc3 10 6 cause cause NN cord-285647-9tegcrc3 10 7 of of IN cord-285647-9tegcrc3 10 8 the the DT cord-285647-9tegcrc3 10 9 major major JJ cord-285647-9tegcrc3 10 10 complications complication NNS cord-285647-9tegcrc3 10 11 of of IN cord-285647-9tegcrc3 10 12 the the DT cord-285647-9tegcrc3 10 13 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 10 14 . . NNP cord-285647-9tegcrc3 10 15 11 11 CD cord-285647-9tegcrc3 10 16 , , , cord-285647-9tegcrc3 10 17 12 12 CD cord-285647-9tegcrc3 11 1 However however RB cord-285647-9tegcrc3 11 2 , , , cord-285647-9tegcrc3 11 3 it -PRON- PRP cord-285647-9tegcrc3 11 4 has have VBZ cord-285647-9tegcrc3 11 5 been be VBN cord-285647-9tegcrc3 11 6 found find VBN cord-285647-9tegcrc3 11 7 that that IN cord-285647-9tegcrc3 11 8 ACE2 ACE2 NNP cord-285647-9tegcrc3 11 9 has have VBZ cord-285647-9tegcrc3 11 10 abundant abundant JJ cord-285647-9tegcrc3 11 11 expression expression NN cord-285647-9tegcrc3 11 12 on on IN cord-285647-9tegcrc3 11 13 endothelia endothelia NNP cord-285647-9tegcrc3 11 14 and and CC cord-285647-9tegcrc3 11 15 smooth smooth JJ cord-285647-9tegcrc3 11 16 muscle muscle NN cord-285647-9tegcrc3 11 17 cells cell NNS cord-285647-9tegcrc3 11 18 of of IN cord-285647-9tegcrc3 11 19 virtually virtually RB cord-285647-9tegcrc3 11 20 all all DT cord-285647-9tegcrc3 11 21 organs organ NNS cord-285647-9tegcrc3 11 22 . . . cord-285647-9tegcrc3 12 1 13 13 CD cord-285647-9tegcrc3 13 1 Therefore therefore RB cord-285647-9tegcrc3 13 2 , , , cord-285647-9tegcrc3 13 3 it -PRON- PRP cord-285647-9tegcrc3 13 4 should should MD cord-285647-9tegcrc3 13 5 be be VB cord-285647-9tegcrc3 13 6 expected expect VBN cord-285647-9tegcrc3 13 7 that that IN cord-285647-9tegcrc3 13 8 after after IN cord-285647-9tegcrc3 13 9 SARS SARS NNP cord-285647-9tegcrc3 13 10 - - HYPH cord-285647-9tegcrc3 13 11 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 13 12 is be VBZ cord-285647-9tegcrc3 13 13 present present JJ cord-285647-9tegcrc3 13 14 in in IN cord-285647-9tegcrc3 13 15 circulation circulation NN cord-285647-9tegcrc3 13 16 , , , cord-285647-9tegcrc3 13 17 it -PRON- PRP cord-285647-9tegcrc3 13 18 can can MD cord-285647-9tegcrc3 13 19 be be VB cord-285647-9tegcrc3 13 20 spread spread VBN cord-285647-9tegcrc3 13 21 across across IN cord-285647-9tegcrc3 13 22 all all DT cord-285647-9tegcrc3 13 23 organs organ NNS cord-285647-9tegcrc3 13 24 . . . cord-285647-9tegcrc3 14 1 In in IN cord-285647-9tegcrc3 14 2 contrast contrast NN cord-285647-9tegcrc3 14 3 , , , cord-285647-9tegcrc3 14 4 both both DT cord-285647-9tegcrc3 14 5 SARS SARS NNP cord-285647-9tegcrc3 14 6 - - HYPH cord-285647-9tegcrc3 14 7 CoV CoV NNP cord-285647-9tegcrc3 14 8 and and CC cord-285647-9tegcrc3 14 9 SARS SARS NNP cord-285647-9tegcrc3 14 10 - - HYPH cord-285647-9tegcrc3 14 11 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 14 12 are be VBP cord-285647-9tegcrc3 14 13 found find VBN cord-285647-9tegcrc3 14 14 specifically specifically RB cord-285647-9tegcrc3 14 15 in in IN cord-285647-9tegcrc3 14 16 some some DT cord-285647-9tegcrc3 14 17 organs organ NNS cord-285647-9tegcrc3 14 18 but but CC cord-285647-9tegcrc3 14 19 not not RB cord-285647-9tegcrc3 14 20 in in IN cord-285647-9tegcrc3 14 21 others other NNS cord-285647-9tegcrc3 14 22 , , , cord-285647-9tegcrc3 14 23 as as IN cord-285647-9tegcrc3 14 24 shown show VBN cord-285647-9tegcrc3 14 25 by by IN cord-285647-9tegcrc3 14 26 in in IN cord-285647-9tegcrc3 14 27 situ situ JJ cord-285647-9tegcrc3 14 28 hybridization hybridization NN cord-285647-9tegcrc3 14 29 studies study NNS cord-285647-9tegcrc3 14 30 for for IN cord-285647-9tegcrc3 14 31 SARS- SARS- NNP cord-285647-9tegcrc3 15 1 CoV. CoV. NNP cord-285647-9tegcrc3 16 1 This this DT cord-285647-9tegcrc3 16 2 was be VBD cord-285647-9tegcrc3 16 3 already already RB cord-285647-9tegcrc3 16 4 remarked remark VBN cord-285647-9tegcrc3 16 5 by by IN cord-285647-9tegcrc3 16 6 Hamming Hamming NNP cord-285647-9tegcrc3 16 7 et et FW cord-285647-9tegcrc3 16 8 al al NNP cord-285647-9tegcrc3 16 9 . . NNP cord-285647-9tegcrc3 16 10 13 13 CD cord-285647-9tegcrc3 16 11 by by IN cord-285647-9tegcrc3 16 12 stressing stress VBG cord-285647-9tegcrc3 16 13 that that IN cord-285647-9tegcrc3 16 14 it -PRON- PRP cord-285647-9tegcrc3 16 15 " " `` cord-285647-9tegcrc3 16 16 is be VBZ cord-285647-9tegcrc3 16 17 remarkable remarkable JJ cord-285647-9tegcrc3 16 18 that that IN cord-285647-9tegcrc3 16 19 so so RB cord-285647-9tegcrc3 16 20 few few JJ cord-285647-9tegcrc3 16 21 organs organ NNS cord-285647-9tegcrc3 16 22 become become VBP cord-285647-9tegcrc3 16 23 viruspositive viruspositive JJ cord-285647-9tegcrc3 16 24 , , , cord-285647-9tegcrc3 16 25 despite despite IN cord-285647-9tegcrc3 16 26 the the DT cord-285647-9tegcrc3 16 27 presence presence NN cord-285647-9tegcrc3 16 28 of of IN cord-285647-9tegcrc3 16 29 ACE2 ACE2 NNP cord-285647-9tegcrc3 16 30 on on IN cord-285647-9tegcrc3 16 31 the the DT cord-285647-9tegcrc3 16 32 endothelia endothelia NN cord-285647-9tegcrc3 16 33 of of IN cord-285647-9tegcrc3 16 34 all all DT cord-285647-9tegcrc3 16 35 organs organ NNS cord-285647-9tegcrc3 16 36 and and CC cord-285647-9tegcrc3 16 37 SARS SARS NNP cord-285647-9tegcrc3 16 38 - - HYPH cord-285647-9tegcrc3 16 39 CoV CoV NNP cord-285647-9tegcrc3 16 40 in in IN cord-285647-9tegcrc3 16 41 blood blood NN cord-285647-9tegcrc3 16 42 plasma plasma NN cord-285647-9tegcrc3 16 43 of of IN cord-285647-9tegcrc3 16 44 infected infected JJ cord-285647-9tegcrc3 16 45 individuals individual NNS cord-285647-9tegcrc3 16 46 . . . cord-285647-9tegcrc3 16 47 " " '' cord-285647-9tegcrc3 17 1 Recently recently RB cord-285647-9tegcrc3 17 2 , , , cord-285647-9tegcrc3 17 3 Gordon Gordon NNP cord-285647-9tegcrc3 17 4 et et NNP cord-285647-9tegcrc3 17 5 al al NNP cord-285647-9tegcrc3 17 6 . . . cord-285647-9tegcrc3 18 1 14 14 CD cord-285647-9tegcrc3 18 2 identified identify VBD cord-285647-9tegcrc3 18 3 human human JJ cord-285647-9tegcrc3 18 4 proteins protein NNS cord-285647-9tegcrc3 18 5 that that WDT cord-285647-9tegcrc3 18 6 interact interact VBP cord-285647-9tegcrc3 18 7 physically physically RB cord-285647-9tegcrc3 18 8 with with IN cord-285647-9tegcrc3 18 9 those those DT cord-285647-9tegcrc3 18 10 of of IN cord-285647-9tegcrc3 18 11 the the DT cord-285647-9tegcrc3 18 12 SARS SARS NNP cord-285647-9tegcrc3 18 13 - - HYPH cord-285647-9tegcrc3 18 14 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 18 15 forming form VBG cord-285647-9tegcrc3 18 16 a a DT cord-285647-9tegcrc3 18 17 high high JJ cord-285647-9tegcrc3 18 18 confidence confidence NN cord-285647-9tegcrc3 18 19 SARS SARS NNP cord-285647-9tegcrc3 18 20 - - HYPH cord-285647-9tegcrc3 18 21 CoV-2-human CoV-2-human NNP cord-285647-9tegcrc3 18 22 protein protein NN cord-285647-9tegcrc3 18 23 - - HYPH cord-285647-9tegcrc3 18 24 protein protein NN cord-285647-9tegcrc3 18 25 interaction interaction NN cord-285647-9tegcrc3 18 26 ( ( -LRB- cord-285647-9tegcrc3 18 27 PPI PPI NNP cord-285647-9tegcrc3 18 28 ) ) -RRB- cord-285647-9tegcrc3 18 29 system system NN cord-285647-9tegcrc3 18 30 . . . cord-285647-9tegcrc3 19 1 Using use VBG cord-285647-9tegcrc3 19 2 this this DT cord-285647-9tegcrc3 19 3 information information NN cord-285647-9tegcrc3 19 4 , , , cord-285647-9tegcrc3 19 5 Gysi Gysi NNP cord-285647-9tegcrc3 19 6 et et NNP cord-285647-9tegcrc3 19 7 al al NNP cord-285647-9tegcrc3 19 8 . . . cord-285647-9tegcrc3 20 1 15 15 CD cord-285647-9tegcrc3 20 2 discovered discover VBD cord-285647-9tegcrc3 20 3 that that IN cord-285647-9tegcrc3 20 4 208 208 CD cord-285647-9tegcrc3 20 5 of of IN cord-285647-9tegcrc3 20 6 the the DT cord-285647-9tegcrc3 20 7 human human JJ cord-285647-9tegcrc3 20 8 proteins protein NNS cord-285647-9tegcrc3 20 9 targeted target VBN cord-285647-9tegcrc3 20 10 by by IN cord-285647-9tegcrc3 20 11 SARS SARS NNP cord-285647-9tegcrc3 20 12 - - HYPH cord-285647-9tegcrc3 20 13 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 20 14 forms form VBZ cord-285647-9tegcrc3 20 15 a a DT cord-285647-9tegcrc3 20 16 connected connected JJ cord-285647-9tegcrc3 20 17 component component NN cord-285647-9tegcrc3 20 18 inside inside IN cord-285647-9tegcrc3 20 19 the the DT cord-285647-9tegcrc3 20 20 human human JJ cord-285647-9tegcrc3 20 21 PPI PPI NNP cord-285647-9tegcrc3 20 22 network network NN cord-285647-9tegcrc3 20 23 . . . cord-285647-9tegcrc3 21 1 That that RB cord-285647-9tegcrc3 21 2 is is RB cord-285647-9tegcrc3 21 3 , , , cord-285647-9tegcrc3 21 4 these these DT cord-285647-9tegcrc3 21 5 208 208 CD cord-285647-9tegcrc3 21 6 are be VBP cord-285647-9tegcrc3 21 7 not not RB cord-285647-9tegcrc3 21 8 randomly randomly RB cord-285647-9tegcrc3 21 9 distributed distribute VBN cord-285647-9tegcrc3 21 10 across across IN cord-285647-9tegcrc3 21 11 the the DT cord-285647-9tegcrc3 21 12 human human JJ cord-285647-9tegcrc3 21 13 proteome proteome NN cord-285647-9tegcrc3 21 14 , , , cord-285647-9tegcrc3 21 15 but but CC cord-285647-9tegcrc3 21 16 they -PRON- PRP cord-285647-9tegcrc3 21 17 are be VBP cord-285647-9tegcrc3 21 18 closely closely RB cord-285647-9tegcrc3 21 19 interconnected interconnect VBN cord-285647-9tegcrc3 21 20 by by IN cord-285647-9tegcrc3 21 21 short short JJ cord-285647-9tegcrc3 21 22 routes route NNS cord-285647-9tegcrc3 21 23 that that WDT cord-285647-9tegcrc3 21 24 allow allow VBP cord-285647-9tegcrc3 21 25 moving move VBG cord-285647-9tegcrc3 21 26 from from IN cord-285647-9tegcrc3 21 27 one one CD cord-285647-9tegcrc3 21 28 to to IN cord-285647-9tegcrc3 21 29 another another DT cord-285647-9tegcrc3 21 30 in in IN cord-285647-9tegcrc3 21 31 just just RB cord-285647-9tegcrc3 21 32 a a DT cord-285647-9tegcrc3 21 33 few few JJ cord-285647-9tegcrc3 21 34 steps step NNS cord-285647-9tegcrc3 21 35 . . . cord-285647-9tegcrc3 22 1 These these DT cord-285647-9tegcrc3 22 2 interdependencies interdependency NNS cord-285647-9tegcrc3 22 3 of of IN cord-285647-9tegcrc3 22 4 protein protein NN cord-285647-9tegcrc3 22 5 - - HYPH cord-285647-9tegcrc3 22 6 protein protein NN cord-285647-9tegcrc3 22 7 interactions interaction NNS cord-285647-9tegcrc3 22 8 are be VBP cord-285647-9tegcrc3 22 9 known know VBN cord-285647-9tegcrc3 22 10 to to TO cord-285647-9tegcrc3 22 11 enable enable VB cord-285647-9tegcrc3 22 12 that that IN cord-285647-9tegcrc3 22 13 perturbations perturbation NNS cord-285647-9tegcrc3 22 14 on on IN cord-285647-9tegcrc3 22 15 one one CD cord-285647-9tegcrc3 22 16 interaction interaction NN cord-285647-9tegcrc3 22 17 propagate propagate VBP cord-285647-9tegcrc3 22 18 across across IN cord-285647-9tegcrc3 22 19 the the DT cord-285647-9tegcrc3 22 20 network network NN cord-285647-9tegcrc3 22 21 and and CC cord-285647-9tegcrc3 22 22 affect affect VB cord-285647-9tegcrc3 22 23 other other JJ cord-285647-9tegcrc3 22 24 interactions interaction NNS cord-285647-9tegcrc3 22 25 . . . cord-285647-9tegcrc3 23 1 [ [ -LRB- cord-285647-9tegcrc3 23 2 16 16 CD cord-285647-9tegcrc3 23 3 ] ] -RRB- cord-285647-9tegcrc3 23 4 [ [ -LRB- cord-285647-9tegcrc3 23 5 17 17 CD cord-285647-9tegcrc3 23 6 ] ] -RRB- cord-285647-9tegcrc3 23 7 [ [ -LRB- cord-285647-9tegcrc3 23 8 18 18 CD cord-285647-9tegcrc3 23 9 ] ] -RRB- cord-285647-9tegcrc3 24 1 [ [ -LRB- cord-285647-9tegcrc3 24 2 19 19 CD cord-285647-9tegcrc3 24 3 ] ] -RRB- cord-285647-9tegcrc3 25 1 In in IN cord-285647-9tegcrc3 25 2 fact fact NN cord-285647-9tegcrc3 25 3 , , , cord-285647-9tegcrc3 25 4 it -PRON- PRP cord-285647-9tegcrc3 25 5 has have VBZ cord-285647-9tegcrc3 25 6 been be VBN cord-285647-9tegcrc3 25 7 signified signify VBN cord-285647-9tegcrc3 25 8 that that IN cord-285647-9tegcrc3 25 9 diseases disease NNS cord-285647-9tegcrc3 25 10 are be VBP cord-285647-9tegcrc3 25 11 a a DT cord-285647-9tegcrc3 25 12 consequence consequence NN cord-285647-9tegcrc3 25 13 of of IN cord-285647-9tegcrc3 25 14 such such JJ cord-285647-9tegcrc3 25 15 perturbation perturbation NN cord-285647-9tegcrc3 25 16 propagation propagation NN cord-285647-9tegcrc3 25 17 . . . cord-285647-9tegcrc3 26 1 [ [ -LRB- cord-285647-9tegcrc3 26 2 20 20 CD cord-285647-9tegcrc3 26 3 ] ] -RRB- cord-285647-9tegcrc3 26 4 [ [ -LRB- cord-285647-9tegcrc3 26 5 21 21 CD cord-285647-9tegcrc3 26 6 ] ] -RRB- cord-285647-9tegcrc3 27 1 [ [ -LRB- cord-285647-9tegcrc3 27 2 22 22 CD cord-285647-9tegcrc3 27 3 ] ] -RRB- cord-285647-9tegcrc3 27 4 It -PRON- PRP cord-285647-9tegcrc3 27 5 has have VBZ cord-285647-9tegcrc3 27 6 been be VBN cord-285647-9tegcrc3 27 7 stressed stress VBN cord-285647-9tegcrc3 27 8 that that IN cord-285647-9tegcrc3 27 9 the the DT cord-285647-9tegcrc3 27 10 protein protein NN cord-285647-9tegcrc3 27 11 - - HYPH cord-285647-9tegcrc3 27 12 protein protein NN cord-285647-9tegcrc3 27 13 interaction interaction NN cord-285647-9tegcrc3 27 14 process process NN cord-285647-9tegcrc3 27 15 requires require VBZ cord-285647-9tegcrc3 27 16 diffusion diffusion NN cord-285647-9tegcrc3 27 17 in in IN cord-285647-9tegcrc3 27 18 their -PRON- PRP$ cord-285647-9tegcrc3 27 19 initial initial JJ cord-285647-9tegcrc3 27 20 stages stage NNS cord-285647-9tegcrc3 27 21 . . . cord-285647-9tegcrc3 28 1 23 23 CD cord-285647-9tegcrc3 29 1 The the DT cord-285647-9tegcrc3 29 2 diffusive diffusive JJ cord-285647-9tegcrc3 29 3 processes process NNS cord-285647-9tegcrc3 29 4 occur occur VBP cord-285647-9tegcrc3 29 5 when when WRB cord-285647-9tegcrc3 29 6 proteins protein NNS cord-285647-9tegcrc3 29 7 , , , cord-285647-9tegcrc3 29 8 possibly possibly RB cord-285647-9tegcrc3 29 9 guided guide VBN cord-285647-9tegcrc3 29 10 by by IN cord-285647-9tegcrc3 29 11 electrostatic electrostatic JJ cord-285647-9tegcrc3 29 12 interactions interaction NNS cord-285647-9tegcrc3 29 13 , , , cord-285647-9tegcrc3 29 14 need need VBP cord-285647-9tegcrc3 29 15 to to TO cord-285647-9tegcrc3 29 16 encounter encounter VB cord-285647-9tegcrc3 29 17 each each DT cord-285647-9tegcrc3 29 18 other other JJ cord-285647-9tegcrc3 29 19 many many JJ cord-285647-9tegcrc3 29 20 times time NNS cord-285647-9tegcrc3 29 21 before before IN cord-285647-9tegcrc3 29 22 forming form VBG cord-285647-9tegcrc3 29 23 an an DT cord-285647-9tegcrc3 29 24 intermediate intermediate NN cord-285647-9tegcrc3 29 25 . . . cord-285647-9tegcrc3 30 1 24 24 CD cord-285647-9tegcrc3 31 1 Not not RB cord-285647-9tegcrc3 31 2 surprisingly surprisingly RB cord-285647-9tegcrc3 31 3 , , , cord-285647-9tegcrc3 31 4 diffusive diffusive JJ cord-285647-9tegcrc3 31 5 processes process NNS cord-285647-9tegcrc3 31 6 have have VBP cord-285647-9tegcrc3 31 7 guided guide VBN cord-285647-9tegcrc3 31 8 several several JJ cord-285647-9tegcrc3 31 9 biologically biologically RB cord-285647-9tegcrc3 31 10 oriented orient VBN cord-285647-9tegcrc3 31 11 searches search NNS cord-285647-9tegcrc3 31 12 in in IN cord-285647-9tegcrc3 31 13 PPI PPI NNP cord-285647-9tegcrc3 31 14 networks network NNS cord-285647-9tegcrc3 31 15 . . . cord-285647-9tegcrc3 32 1 25 25 CD cord-285647-9tegcrc3 32 2 , , , cord-285647-9tegcrc3 32 3 26 26 CD cord-285647-9tegcrc3 33 1 Therefore therefore RB cord-285647-9tegcrc3 33 2 , , , cord-285647-9tegcrc3 33 3 we -PRON- PRP cord-285647-9tegcrc3 33 4 assume assume VBP cord-285647-9tegcrc3 33 5 here here RB cord-285647-9tegcrc3 33 6 that that IN cord-285647-9tegcrc3 33 7 perturbations perturbation NNS cord-285647-9tegcrc3 33 8 produced produce VBN cord-285647-9tegcrc3 33 9 by by IN cord-285647-9tegcrc3 33 10 SARS SARS NNP cord-285647-9tegcrc3 33 11 - - HYPH cord-285647-9tegcrc3 33 12 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 33 13 proteins protein NNS cord-285647-9tegcrc3 33 14 on on IN cord-285647-9tegcrc3 33 15 the the DT cord-285647-9tegcrc3 33 16 human human JJ cord-285647-9tegcrc3 33 17 PPI PPI NNP cord-285647-9tegcrc3 33 18 network network NN cord-285647-9tegcrc3 33 19 are be VBP cord-285647-9tegcrc3 33 20 propagated propagate VBN cord-285647-9tegcrc3 33 21 by by IN cord-285647-9tegcrc3 33 22 means mean NNS cord-285647-9tegcrc3 33 23 of of IN cord-285647-9tegcrc3 33 24 diffusive diffusive JJ cord-285647-9tegcrc3 33 25 processes process NNS cord-285647-9tegcrc3 33 26 . . . cord-285647-9tegcrc3 34 1 However however RB cord-285647-9tegcrc3 34 2 , , , cord-285647-9tegcrc3 34 3 due due IN cord-285647-9tegcrc3 34 4 to to IN cord-285647-9tegcrc3 34 5 the the DT cord-285647-9tegcrc3 34 6 crowded crowded JJ cord-285647-9tegcrc3 34 7 nature nature NN cord-285647-9tegcrc3 34 8 of of IN cord-285647-9tegcrc3 34 9 the the DT cord-285647-9tegcrc3 34 10 intra intra JJ cord-285647-9tegcrc3 34 11 - - JJ cord-285647-9tegcrc3 34 12 cell cell JJ cord-285647-9tegcrc3 34 13 space space NN cord-285647-9tegcrc3 34 14 and and CC cord-285647-9tegcrc3 34 15 the the DT cord-285647-9tegcrc3 34 16 presence presence NN cord-285647-9tegcrc3 34 17 in in IN cord-285647-9tegcrc3 34 18 it -PRON- PRP cord-285647-9tegcrc3 34 19 of of IN cord-285647-9tegcrc3 34 20 spatial spatial JJ cord-285647-9tegcrc3 34 21 barriers barrier NNS cord-285647-9tegcrc3 34 22 , , , cord-285647-9tegcrc3 34 23 subdiffusive subdiffusive NNP cord-285647-9tegcrc3 34 24 processes process VBZ cord-285647-9tegcrc3 34 25 more more RBR cord-285647-9tegcrc3 34 26 than than IN cord-285647-9tegcrc3 34 27 normal normal JJ cord-285647-9tegcrc3 34 28 diffusion diffusion NN cord-285647-9tegcrc3 34 29 are be VBP cord-285647-9tegcrc3 34 30 expected expect VBN cord-285647-9tegcrc3 34 31 for for IN cord-285647-9tegcrc3 34 32 these these DT cord-285647-9tegcrc3 34 33 protein protein NN cord-285647-9tegcrc3 34 34 - - HYPH cord-285647-9tegcrc3 34 35 protein protein NN cord-285647-9tegcrc3 34 36 encounters encounter NNS cord-285647-9tegcrc3 34 37 . . . cord-285647-9tegcrc3 35 1 [ [ -LRB- cord-285647-9tegcrc3 35 2 27 27 CD cord-285647-9tegcrc3 35 3 ] ] -RRB- cord-285647-9tegcrc3 35 4 [ [ -LRB- cord-285647-9tegcrc3 35 5 28 28 CD cord-285647-9tegcrc3 35 6 ] ] -RRB- cord-285647-9tegcrc3 36 1 [ [ -LRB- cord-285647-9tegcrc3 36 2 29 29 CD cord-285647-9tegcrc3 36 3 ] ] -RRB- cord-285647-9tegcrc3 37 1 This this DT cord-285647-9tegcrc3 37 2 creates create VBZ cord-285647-9tegcrc3 37 3 another another DT cord-285647-9tegcrc3 37 4 difficulty difficulty NN cord-285647-9tegcrc3 37 5 , , , cord-285647-9tegcrc3 37 6 as as IN cord-285647-9tegcrc3 37 7 remarked remark VBN cord-285647-9tegcrc3 37 8 by by IN cord-285647-9tegcrc3 37 9 Batada Batada NNP cord-285647-9tegcrc3 37 10 et et NNP cord-285647-9tegcrc3 37 11 al al NNP cord-285647-9tegcrc3 37 12 . . . cord-285647-9tegcrc3 38 1 , , , cord-285647-9tegcrc3 38 2 23 23 CD cord-285647-9tegcrc3 38 3 which which WDT cord-285647-9tegcrc3 38 4 is be VBZ cord-285647-9tegcrc3 38 5 that that IN cord-285647-9tegcrc3 38 6 such such JJ cord-285647-9tegcrc3 38 7 ( ( -LRB- cord-285647-9tegcrc3 38 8 sub)diffusive sub)diffusive IN cord-285647-9tegcrc3 38 9 processes process NNS cord-285647-9tegcrc3 38 10 along along RB cord-285647-9tegcrc3 38 11 are be VBP cord-285647-9tegcrc3 38 12 not not RB cord-285647-9tegcrc3 38 13 sufficient sufficient JJ cord-285647-9tegcrc3 38 14 for for IN cord-285647-9tegcrc3 38 15 carrying carry VBG cord-285647-9tegcrc3 38 16 out out RP cord-285647-9tegcrc3 38 17 cellular cellular JJ cord-285647-9tegcrc3 38 18 processes process NNS cord-285647-9tegcrc3 38 19 at at IN cord-285647-9tegcrc3 38 20 a a DT cord-285647-9tegcrc3 38 21 significant significant JJ cord-285647-9tegcrc3 38 22 rate rate NN cord-285647-9tegcrc3 38 23 in in IN cord-285647-9tegcrc3 38 24 cells cell NNS cord-285647-9tegcrc3 38 25 . . . cord-285647-9tegcrc3 39 1 Here here RB cord-285647-9tegcrc3 39 2 , , , cord-285647-9tegcrc3 39 3 we -PRON- PRP cord-285647-9tegcrc3 39 4 propose propose VBP cord-285647-9tegcrc3 39 5 the the DT cord-285647-9tegcrc3 39 6 use use NN cord-285647-9tegcrc3 39 7 of of IN cord-285647-9tegcrc3 39 8 a a DT cord-285647-9tegcrc3 39 9 time time NN cord-285647-9tegcrc3 39 10 - - HYPH cord-285647-9tegcrc3 39 11 fractional fractional JJ cord-285647-9tegcrc3 39 12 diffusion diffusion NN cord-285647-9tegcrc3 39 13 model model NN cord-285647-9tegcrc3 39 14 on on IN cord-285647-9tegcrc3 39 15 the the DT cord-285647-9tegcrc3 39 16 PPI PPI NNP cord-285647-9tegcrc3 39 17 network network NN cord-285647-9tegcrc3 39 18 of of IN cord-285647-9tegcrc3 39 19 proteins protein NNS cord-285647-9tegcrc3 39 20 targeted target VBN cord-285647-9tegcrc3 39 21 by by IN cord-285647-9tegcrc3 39 22 SARS SARS NNP cord-285647-9tegcrc3 39 23 - - HYPH cord-285647-9tegcrc3 39 24 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 39 25 . . . cord-285647-9tegcrc3 40 1 The the DT cord-285647-9tegcrc3 40 2 goal goal NN cord-285647-9tegcrc3 40 3 is be VBZ cord-285647-9tegcrc3 40 4 to to TO cord-285647-9tegcrc3 40 5 model model VB cord-285647-9tegcrc3 40 6 the the DT cord-285647-9tegcrc3 40 7 propagation propagation NN cord-285647-9tegcrc3 40 8 of of IN cord-285647-9tegcrc3 40 9 the the DT cord-285647-9tegcrc3 40 10 perturbations perturbation NNS cord-285647-9tegcrc3 40 11 produced produce VBN cord-285647-9tegcrc3 40 12 by by IN cord-285647-9tegcrc3 40 13 the the DT cord-285647-9tegcrc3 40 14 interactions interaction NNS cord-285647-9tegcrc3 40 15 of of IN cord-285647-9tegcrc3 40 16 human human JJ cord-285647-9tegcrc3 40 17 proteins protein NNS cord-285647-9tegcrc3 40 18 with with IN cord-285647-9tegcrc3 40 19 those those DT cord-285647-9tegcrc3 40 20 of of IN cord-285647-9tegcrc3 40 21 SARS SARS NNP cord-285647-9tegcrc3 40 22 - - : cord-285647-9tegcrc3 40 23 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 40 24 through through IN cord-285647-9tegcrc3 40 25 the the DT cord-285647-9tegcrc3 40 26 whole whole JJ cord-285647-9tegcrc3 40 27 PPI ppi NN cord-285647-9tegcrc3 40 28 . . . cord-285647-9tegcrc3 41 1 The the DT cord-285647-9tegcrc3 41 2 subdiffusive subdiffusive NN cord-285647-9tegcrc3 41 3 process process NN cord-285647-9tegcrc3 41 4 emerging emerge VBG cord-285647-9tegcrc3 41 5 from from IN cord-285647-9tegcrc3 41 6 the the DT cord-285647-9tegcrc3 41 7 application application NN cord-285647-9tegcrc3 41 8 of of IN cord-285647-9tegcrc3 41 9 this this DT cord-285647-9tegcrc3 41 10 model model NN cord-285647-9tegcrc3 41 11 to to IN cord-285647-9tegcrc3 41 12 the the DT cord-285647-9tegcrc3 41 13 SARS- sars- NN cord-285647-9tegcrc3 42 1 CoV-2-human cov-2-human NN cord-285647-9tegcrc3 42 2 PPIs ppi NNS cord-285647-9tegcrc3 42 3 has have VBZ cord-285647-9tegcrc3 42 4 a a DT cord-285647-9tegcrc3 42 5 very very RB cord-285647-9tegcrc3 42 6 small small JJ cord-285647-9tegcrc3 42 7 rate rate NN cord-285647-9tegcrc3 42 8 of of IN cord-285647-9tegcrc3 42 9 convergence convergence NN cord-285647-9tegcrc3 42 10 to to IN cord-285647-9tegcrc3 42 11 the the DT cord-285647-9tegcrc3 42 12 steady steady JJ cord-285647-9tegcrc3 42 13 state state NN cord-285647-9tegcrc3 42 14 . . . cord-285647-9tegcrc3 43 1 However however RB cord-285647-9tegcrc3 43 2 , , , cord-285647-9tegcrc3 43 3 this this DT cord-285647-9tegcrc3 43 4 process process NN cord-285647-9tegcrc3 43 5 produces produce VBZ cord-285647-9tegcrc3 43 6 a a DT cord-285647-9tegcrc3 43 7 dramatic dramatic JJ cord-285647-9tegcrc3 43 8 increment increment NN cord-285647-9tegcrc3 43 9 of of IN cord-285647-9tegcrc3 43 10 the the DT cord-285647-9tegcrc3 43 11 probability probability NN cord-285647-9tegcrc3 43 12 that that IN cord-285647-9tegcrc3 43 13 certain certain JJ cord-285647-9tegcrc3 43 14 proteins protein NNS cord-285647-9tegcrc3 43 15 are be VBP cord-285647-9tegcrc3 43 16 perturbed perturb VBN cord-285647-9tegcrc3 43 17 at at IN cord-285647-9tegcrc3 43 18 very very RB cord-285647-9tegcrc3 43 19 short short JJ cord-285647-9tegcrc3 43 20 times time NNS cord-285647-9tegcrc3 43 21 . . . cord-285647-9tegcrc3 44 1 This this DT cord-285647-9tegcrc3 44 2 kind kind NN cord-285647-9tegcrc3 44 3 of of IN cord-285647-9tegcrc3 44 4 shock shock NN cord-285647-9tegcrc3 44 5 wave wave NN cord-285647-9tegcrc3 44 6 effect effect NN cord-285647-9tegcrc3 44 7 of of IN cord-285647-9tegcrc3 44 8 the the DT cord-285647-9tegcrc3 44 9 transmission transmission NN cord-285647-9tegcrc3 44 10 of of IN cord-285647-9tegcrc3 44 11 perturbations perturbation NNS cord-285647-9tegcrc3 44 12 occurs occur VBZ cord-285647-9tegcrc3 44 13 at at RB cord-285647-9tegcrc3 44 14 much much RB cord-285647-9tegcrc3 44 15 earlier early JJR cord-285647-9tegcrc3 44 16 times time NNS cord-285647-9tegcrc3 44 17 in in IN cord-285647-9tegcrc3 44 18 the the DT cord-285647-9tegcrc3 44 19 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 44 20 regime regime NN cord-285647-9tegcrc3 44 21 than than IN cord-285647-9tegcrc3 44 22 at at IN cord-285647-9tegcrc3 44 23 the the DT cord-285647-9tegcrc3 44 24 normal normal JJ cord-285647-9tegcrc3 44 25 diffusion diffusion NN cord-285647-9tegcrc3 44 26 one one CD cord-285647-9tegcrc3 44 27 . . . cord-285647-9tegcrc3 45 1 Therefore therefore RB cord-285647-9tegcrc3 45 2 , , , cord-285647-9tegcrc3 45 3 we -PRON- PRP cord-285647-9tegcrc3 45 4 propose propose VBP cord-285647-9tegcrc3 45 5 here here RB cord-285647-9tegcrc3 45 6 a a DT cord-285647-9tegcrc3 45 7 switch switch NN cord-285647-9tegcrc3 45 8 and and CC cord-285647-9tegcrc3 45 9 restart restart VB cord-285647-9tegcrc3 45 10 process process NN cord-285647-9tegcrc3 45 11 in in IN cord-285647-9tegcrc3 45 12 which which WDT cord-285647-9tegcrc3 45 13 a a DT cord-285647-9tegcrc3 45 14 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 45 15 process process NN cord-285647-9tegcrc3 45 16 starts start VBZ cord-285647-9tegcrc3 45 17 at at IN cord-285647-9tegcrc3 45 18 a a DT cord-285647-9tegcrc3 45 19 given give VBN cord-285647-9tegcrc3 45 20 protein protein NN cord-285647-9tegcrc3 45 21 of of IN cord-285647-9tegcrc3 45 22 the the DT cord-285647-9tegcrc3 45 23 PPI PPI NNP cord-285647-9tegcrc3 45 24 , , , cord-285647-9tegcrc3 45 25 perturbs perturb VBZ cord-285647-9tegcrc3 45 26 a a DT cord-285647-9tegcrc3 45 27 few few JJ cord-285647-9tegcrc3 45 28 others other NNS cord-285647-9tegcrc3 45 29 , , , cord-285647-9tegcrc3 45 30 which which WDT cord-285647-9tegcrc3 45 31 then then RB cord-285647-9tegcrc3 45 32 become become VBP cord-285647-9tegcrc3 45 33 the the DT cord-285647-9tegcrc3 45 34 starting starting NN cord-285647-9tegcrc3 45 35 point point NN cord-285647-9tegcrc3 45 36 of of IN cord-285647-9tegcrc3 45 37 a a DT cord-285647-9tegcrc3 45 38 new new JJ cord-285647-9tegcrc3 45 39 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 45 40 process process NN cord-285647-9tegcrc3 45 41 and and CC cord-285647-9tegcrc3 45 42 so so RB cord-285647-9tegcrc3 45 43 on on RB cord-285647-9tegcrc3 45 44 . . . cord-285647-9tegcrc3 46 1 Using use VBG cord-285647-9tegcrc3 46 2 this this DT cord-285647-9tegcrc3 46 3 approach approach NN cord-285647-9tegcrc3 46 4 , , , cord-285647-9tegcrc3 46 5 we -PRON- PRP cord-285647-9tegcrc3 46 6 then then RB cord-285647-9tegcrc3 46 7 analyze analyze VBP cord-285647-9tegcrc3 46 8 how how WRB cord-285647-9tegcrc3 46 9 the the DT cord-285647-9tegcrc3 46 10 initial initial JJ cord-285647-9tegcrc3 46 11 interaction interaction NN cord-285647-9tegcrc3 46 12 of of IN cord-285647-9tegcrc3 46 13 the the DT cord-285647-9tegcrc3 46 14 SARS SARS NNP cord-285647-9tegcrc3 46 15 - - HYPH cord-285647-9tegcrc3 46 16 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 46 17 spike spike NN cord-285647-9tegcrc3 46 18 protein protein NN cord-285647-9tegcrc3 46 19 with with IN cord-285647-9tegcrc3 46 20 a a DT cord-285647-9tegcrc3 46 21 human human JJ cord-285647-9tegcrc3 46 22 protein protein NN cord-285647-9tegcrc3 46 23 propagates propagate VBZ cord-285647-9tegcrc3 46 24 across across IN cord-285647-9tegcrc3 46 25 the the DT cord-285647-9tegcrc3 46 26 whole whole JJ cord-285647-9tegcrc3 46 27 network network NN cord-285647-9tegcrc3 46 28 . . . cord-285647-9tegcrc3 47 1 We -PRON- PRP cord-285647-9tegcrc3 47 2 discover discover VBP cord-285647-9tegcrc3 47 3 some some DT cord-285647-9tegcrc3 47 4 potential potential JJ cord-285647-9tegcrc3 47 5 routes route NNS cord-285647-9tegcrc3 47 6 of of IN cord-285647-9tegcrc3 47 7 propagation propagation NN cord-285647-9tegcrc3 47 8 of of IN cord-285647-9tegcrc3 47 9 these these DT cord-285647-9tegcrc3 47 10 perturbations perturbation NNS cord-285647-9tegcrc3 47 11 from from IN cord-285647-9tegcrc3 47 12 proteins protein NNS cord-285647-9tegcrc3 47 13 mainly mainly RB cord-285647-9tegcrc3 47 14 expressed express VBN cord-285647-9tegcrc3 47 15 in in IN cord-285647-9tegcrc3 47 16 the the DT cord-285647-9tegcrc3 47 17 lungs lung NNS cord-285647-9tegcrc3 47 18 to to IN cord-285647-9tegcrc3 47 19 proteins protein NNS cord-285647-9tegcrc3 47 20 mainly mainly RB cord-285647-9tegcrc3 47 21 expressed express VBN cord-285647-9tegcrc3 47 22 in in IN cord-285647-9tegcrc3 47 23 other other JJ cord-285647-9tegcrc3 47 24 different different JJ cord-285647-9tegcrc3 47 25 tissues tissue NNS cord-285647-9tegcrc3 47 26 , , , cord-285647-9tegcrc3 47 27 such such JJ cord-285647-9tegcrc3 47 28 as as IN cord-285647-9tegcrc3 47 29 the the DT cord-285647-9tegcrc3 47 30 heart heart NN cord-285647-9tegcrc3 47 31 , , , cord-285647-9tegcrc3 47 32 cerebral cerebral JJ cord-285647-9tegcrc3 47 33 cortex cortex NN cord-285647-9tegcrc3 47 34 , , , cord-285647-9tegcrc3 47 35 thymus thymus NN cord-285647-9tegcrc3 47 36 , , , cord-285647-9tegcrc3 47 37 lymph lymph NN cord-285647-9tegcrc3 47 38 node node NN cord-285647-9tegcrc3 47 39 , , , cord-285647-9tegcrc3 47 40 testis testis NN cord-285647-9tegcrc3 47 41 , , , cord-285647-9tegcrc3 47 42 prostate prostate NN cord-285647-9tegcrc3 47 43 , , , cord-285647-9tegcrc3 47 44 liver liver NN cord-285647-9tegcrc3 47 45 , , , cord-285647-9tegcrc3 47 46 small small JJ cord-285647-9tegcrc3 47 47 intestine intestine NN cord-285647-9tegcrc3 47 48 , , , cord-285647-9tegcrc3 47 49 duodenum duodenum NN cord-285647-9tegcrc3 47 50 , , , cord-285647-9tegcrc3 47 51 kidney kidney NN cord-285647-9tegcrc3 47 52 , , , cord-285647-9tegcrc3 47 53 among among IN cord-285647-9tegcrc3 47 54 others other NNS cord-285647-9tegcrc3 47 55 . . . cord-285647-9tegcrc3 48 1 A. a. LS cord-285647-9tegcrc3 48 2 Settling settle VBG cord-285647-9tegcrc3 48 3 a a DT cord-285647-9tegcrc3 48 4 model model NN cord-285647-9tegcrc3 49 1 The the DT cord-285647-9tegcrc3 49 2 problem problem NN cord-285647-9tegcrc3 49 3 we -PRON- PRP cord-285647-9tegcrc3 49 4 intend intend VBP cord-285647-9tegcrc3 49 5 to to TO cord-285647-9tegcrc3 49 6 model model VB cord-285647-9tegcrc3 49 7 here here RB cord-285647-9tegcrc3 49 8 is be VBZ cord-285647-9tegcrc3 49 9 of of IN cord-285647-9tegcrc3 49 10 a a DT cord-285647-9tegcrc3 49 11 large large JJ cord-285647-9tegcrc3 49 12 complexity complexity NN cord-285647-9tegcrc3 49 13 as as IN cord-285647-9tegcrc3 49 14 it -PRON- PRP cord-285647-9tegcrc3 49 15 deals deal VBZ cord-285647-9tegcrc3 49 16 with with IN cord-285647-9tegcrc3 49 17 the the DT cord-285647-9tegcrc3 49 18 propagation propagation NN cord-285647-9tegcrc3 49 19 of of IN cord-285647-9tegcrc3 49 20 perturbations perturbation NNS cord-285647-9tegcrc3 49 21 across across IN cord-285647-9tegcrc3 49 22 a a DT cord-285647-9tegcrc3 49 23 network network NN cord-285647-9tegcrc3 49 24 of of IN cord-285647-9tegcrc3 49 25 interacting interact VBG cord-285647-9tegcrc3 49 26 proteins protein NNS cord-285647-9tegcrc3 49 27 , , , cord-285647-9tegcrc3 49 28 each each DT cord-285647-9tegcrc3 49 29 of of IN cord-285647-9tegcrc3 49 30 which which WDT cord-285647-9tegcrc3 49 31 is be VBZ cord-285647-9tegcrc3 49 32 located locate VBN cord-285647-9tegcrc3 49 33 in in IN cord-285647-9tegcrc3 49 34 a a DT cord-285647-9tegcrc3 49 35 crowded crowded JJ cord-285647-9tegcrc3 49 36 intracellular intracellular JJ cord-285647-9tegcrc3 49 37 space space NN cord-285647-9tegcrc3 49 38 . . . cord-285647-9tegcrc3 50 1 Therefore therefore RB cord-285647-9tegcrc3 50 2 , , , cord-285647-9tegcrc3 50 3 we -PRON- PRP cord-285647-9tegcrc3 50 4 necessarily necessarily RB cord-285647-9tegcrc3 50 5 have have VBP cord-285647-9tegcrc3 50 6 to to TO cord-285647-9tegcrc3 50 7 impose impose VB cord-285647-9tegcrc3 50 8 restrictions restriction NNS cord-285647-9tegcrc3 50 9 and and CC cord-285647-9tegcrc3 50 10 make make VB cord-285647-9tegcrc3 50 11 assumptions assumption NNS cord-285647-9tegcrc3 50 12 to to TO cord-285647-9tegcrc3 50 13 settle settle VB cord-285647-9tegcrc3 50 14 our -PRON- PRP$ cord-285647-9tegcrc3 50 15 modeling modeling NN cord-285647-9tegcrc3 50 16 framework framework NN cord-285647-9tegcrc3 50 17 . . . cord-285647-9tegcrc3 51 1 As as IN cord-285647-9tegcrc3 51 2 we -PRON- PRP cord-285647-9tegcrc3 51 3 have have VBP cord-285647-9tegcrc3 51 4 mentioned mention VBN cord-285647-9tegcrc3 51 5 in in IN cord-285647-9tegcrc3 51 6 Sec Sec NNP cord-285647-9tegcrc3 51 7 . . . cord-285647-9tegcrc3 52 1 I -PRON- PRP cord-285647-9tegcrc3 52 2 , , , cord-285647-9tegcrc3 52 3 protein protein NN cord-285647-9tegcrc3 52 4 encounters encounter NNS cord-285647-9tegcrc3 52 5 should should MD cord-285647-9tegcrc3 52 6 necessarily necessarily RB cord-285647-9tegcrc3 52 7 occur occur VB cord-285647-9tegcrc3 52 8 in in IN cord-285647-9tegcrc3 52 9 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 52 10 ways way NNS cord-285647-9tegcrc3 52 11 due due JJ cord-285647-9tegcrc3 52 12 to to IN cord-285647-9tegcrc3 52 13 the the DT cord-285647-9tegcrc3 52 14 crowded crowded JJ cord-285647-9tegcrc3 52 15 environment environment NN cord-285647-9tegcrc3 52 16 in in IN cord-285647-9tegcrc3 52 17 which which WDT cord-285647-9tegcrc3 52 18 they -PRON- PRP cord-285647-9tegcrc3 52 19 are be VBP cord-285647-9tegcrc3 52 20 embedded embed VBN cord-285647-9tegcrc3 52 21 , , , cord-285647-9tegcrc3 52 22 as as RB cord-285647-9tegcrc3 52 23 well well RB cord-285647-9tegcrc3 52 24 as as IN cord-285647-9tegcrc3 52 25 the the DT cord-285647-9tegcrc3 52 26 existence existence NN cord-285647-9tegcrc3 52 27 of of IN cord-285647-9tegcrc3 52 28 immobile immobile JJ cord-285647-9tegcrc3 52 29 obstacles obstacle NNS cord-285647-9tegcrc3 52 30 such such JJ cord-285647-9tegcrc3 52 31 as as IN cord-285647-9tegcrc3 52 32 membranes membrane NNS cord-285647-9tegcrc3 52 33 . . . cord-285647-9tegcrc3 53 1 By by IN cord-285647-9tegcrc3 53 2 a a DT cord-285647-9tegcrc3 53 3 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 53 4 process process NN cord-285647-9tegcrc3 53 5 , , , cord-285647-9tegcrc3 53 6 we -PRON- PRP cord-285647-9tegcrc3 53 7 understand understand VBP cord-285647-9tegcrc3 53 8 that that IN cord-285647-9tegcrc3 53 9 the the DT cord-285647-9tegcrc3 53 10 mean mean JJ cord-285647-9tegcrc3 53 11 square square JJ cord-285647-9tegcrc3 53 12 displacement displacement NN cord-285647-9tegcrc3 53 13 of of IN cord-285647-9tegcrc3 53 14 a a DT cord-285647-9tegcrc3 53 15 protein protein NN cord-285647-9tegcrc3 53 16 scales scale NNS cord-285647-9tegcrc3 53 17 as as IN cord-285647-9tegcrc3 53 18 where where WRB cord-285647-9tegcrc3 53 19 0 0 CD cord-285647-9tegcrc3 53 20 < < XX cord-285647-9tegcrc3 53 21 κ κ XX cord-285647-9tegcrc3 53 22 < < XX cord-285647-9tegcrc3 53 23 1 1 CD cord-285647-9tegcrc3 53 24 is be VBZ cord-285647-9tegcrc3 53 25 the the DT cord-285647-9tegcrc3 53 26 anomalous anomalous JJ cord-285647-9tegcrc3 53 27 diffusion diffusion NN cord-285647-9tegcrc3 53 28 exponent exponent NN cord-285647-9tegcrc3 53 29 . . . cord-285647-9tegcrc3 54 1 As as IN cord-285647-9tegcrc3 54 2 observed observe VBN cord-285647-9tegcrc3 54 3 by by IN cord-285647-9tegcrc3 54 4 Sposini Sposini NNP cord-285647-9tegcrc3 54 5 et et NNP cord-285647-9tegcrc3 54 6 al al NNP cord-285647-9tegcrc3 54 7 . . NNP cord-285647-9tegcrc3 54 8 , , , cord-285647-9tegcrc3 54 9 30 30 CD cord-285647-9tegcrc3 54 10 these these DT cord-285647-9tegcrc3 54 11 anomalous anomalous JJ cord-285647-9tegcrc3 54 12 diffusive diffusive JJ cord-285647-9tegcrc3 54 13 processes process NNS cord-285647-9tegcrc3 54 14 can can MD cord-285647-9tegcrc3 54 15 emerge emerge VB cord-285647-9tegcrc3 54 16 from from IN cord-285647-9tegcrc3 54 17 ( ( -LRB- cord-285647-9tegcrc3 54 18 i i NN cord-285647-9tegcrc3 54 19 ) ) -RRB- cord-285647-9tegcrc3 54 20 continuous continuous JJ cord-285647-9tegcrc3 54 21 time time NN cord-285647-9tegcrc3 54 22 random random JJ cord-285647-9tegcrc3 54 23 walk walk NN cord-285647-9tegcrc3 54 24 ( ( -LRB- cord-285647-9tegcrc3 54 25 CTRW CTRW NNP cord-285647-9tegcrc3 54 26 ) ) -RRB- cord-285647-9tegcrc3 54 27 processes process NNS cord-285647-9tegcrc3 54 28 or or CC cord-285647-9tegcrc3 54 29 by by IN cord-285647-9tegcrc3 54 30 ( ( -LRB- cord-285647-9tegcrc3 54 31 ii ii NN cord-285647-9tegcrc3 54 32 ) ) -RRB- cord-285647-9tegcrc3 54 33 viscoelastic viscoelastic JJ cord-285647-9tegcrc3 54 34 diffusion diffusion NN cord-285647-9tegcrc3 54 35 processes process NNS cord-285647-9tegcrc3 54 36 . . . cord-285647-9tegcrc3 55 1 In in IN cord-285647-9tegcrc3 55 2 the the DT cord-285647-9tegcrc3 55 3 first first JJ cord-285647-9tegcrc3 55 4 case case NN cord-285647-9tegcrc3 55 5 , , , cord-285647-9tegcrc3 55 6 the the DT cord-285647-9tegcrc3 55 7 " " `` cord-285647-9tegcrc3 55 8 anomaly anomaly NN cord-285647-9tegcrc3 55 9 " " '' cord-285647-9tegcrc3 55 10 is be VBZ cord-285647-9tegcrc3 55 11 created create VBN cord-285647-9tegcrc3 55 12 by by IN cord-285647-9tegcrc3 55 13 power power NN cord-285647-9tegcrc3 55 14 - - HYPH cord-285647-9tegcrc3 55 15 law law NN cord-285647-9tegcrc3 55 16 waiting waiting NN cord-285647-9tegcrc3 55 17 times time NNS cord-285647-9tegcrc3 55 18 in in IN cord-285647-9tegcrc3 55 19 between between IN cord-285647-9tegcrc3 55 20 motion motion NN cord-285647-9tegcrc3 55 21 events event NNS cord-285647-9tegcrc3 55 22 . . . cord-285647-9tegcrc3 56 1 This this DT cord-285647-9tegcrc3 56 2 kind kind NN cord-285647-9tegcrc3 56 3 of of IN cord-285647-9tegcrc3 56 4 processes process NNS cord-285647-9tegcrc3 56 5 is be VBZ cord-285647-9tegcrc3 56 6 mainly mainly RB cord-285647-9tegcrc3 56 7 accounted account VBN cord-285647-9tegcrc3 56 8 for for IN cord-285647-9tegcrc3 56 9 by by IN cord-285647-9tegcrc3 56 10 the the DT cord-285647-9tegcrc3 56 11 generalized generalized JJ cord-285647-9tegcrc3 56 12 Langevin Langevin NNP cord-285647-9tegcrc3 56 13 equation equation NN cord-285647-9tegcrc3 56 14 with with IN cord-285647-9tegcrc3 56 15 the the DT cord-285647-9tegcrc3 56 16 power power NN cord-285647-9tegcrc3 56 17 - - HYPH cord-285647-9tegcrc3 56 18 law law NN cord-285647-9tegcrc3 56 19 friction friction NN cord-285647-9tegcrc3 56 20 kernel kernel NN cord-285647-9tegcrc3 56 21 as as RB cord-285647-9tegcrc3 56 22 well well RB cord-285647-9tegcrc3 56 23 as as IN cord-285647-9tegcrc3 56 24 by by IN cord-285647-9tegcrc3 56 25 fractional fractional JJ cord-285647-9tegcrc3 56 26 Brownian Brownian NNP cord-285647-9tegcrc3 56 27 motion motion NN cord-285647-9tegcrc3 56 28 ( ( -LRB- cord-285647-9tegcrc3 56 29 FBM FBM NNP cord-285647-9tegcrc3 56 30 ) ) -RRB- cord-285647-9tegcrc3 56 31 . . . cord-285647-9tegcrc3 57 1 While while IN cord-285647-9tegcrc3 57 2 the the DT cord-285647-9tegcrc3 57 3 first first JJ cord-285647-9tegcrc3 57 4 processes process NNS cord-285647-9tegcrc3 57 5 are be VBP cord-285647-9tegcrc3 57 6 characterized characterize VBN cord-285647-9tegcrc3 57 7 by by IN cord-285647-9tegcrc3 57 8 the the DT cord-285647-9tegcrc3 57 9 stretched stretch VBN cord-285647-9tegcrc3 57 10 Gaussian gaussian JJ cord-285647-9tegcrc3 57 11 displacement displacement NN cord-285647-9tegcrc3 57 12 probability probability NN cord-285647-9tegcrc3 57 13 density density NN cord-285647-9tegcrc3 57 14 , , , cord-285647-9tegcrc3 57 15 weak weak JJ cord-285647-9tegcrc3 57 16 ergodicity ergodicity NN cord-285647-9tegcrc3 57 17 , , , cord-285647-9tegcrc3 57 18 and and CC cord-285647-9tegcrc3 57 19 aging age VBG cord-285647-9tegcrc3 57 20 , , , cord-285647-9tegcrc3 57 21 the the DT cord-285647-9tegcrc3 57 22 second second JJ cord-285647-9tegcrc3 57 23 ones one NNS cord-285647-9tegcrc3 57 24 are be VBP cord-285647-9tegcrc3 57 25 ergodic ergodic JJ cord-285647-9tegcrc3 57 26 processes process NNS cord-285647-9tegcrc3 57 27 characterized characterize VBN cord-285647-9tegcrc3 57 28 by by IN cord-285647-9tegcrc3 57 29 the the DT cord-285647-9tegcrc3 57 30 Gaussian gaussian JJ cord-285647-9tegcrc3 57 31 density density NN cord-285647-9tegcrc3 57 32 probability probability NN cord-285647-9tegcrc3 57 33 distribution distribution NN cord-285647-9tegcrc3 57 34 . . . cord-285647-9tegcrc3 58 1 Therefore therefore RB cord-285647-9tegcrc3 58 2 , , , cord-285647-9tegcrc3 58 3 our -PRON- PRP$ cord-285647-9tegcrc3 58 4 first first JJ cord-285647-9tegcrc3 58 5 task task NN cord-285647-9tegcrc3 58 6 is be VBZ cord-285647-9tegcrc3 58 7 to to TO cord-285647-9tegcrc3 58 8 discern discern VB cord-285647-9tegcrc3 58 9 which which WDT cord-285647-9tegcrc3 58 10 of of IN cord-285647-9tegcrc3 58 11 these these DT cord-285647-9tegcrc3 58 12 two two CD cord-285647-9tegcrc3 58 13 kinds kind NNS cord-285647-9tegcrc3 58 14 of of IN cord-285647-9tegcrc3 58 15 approaches approach NNS cord-285647-9tegcrc3 58 16 is be VBZ cord-285647-9tegcrc3 58 17 appropriate appropriate JJ cord-285647-9tegcrc3 58 18 for for IN cord-285647-9tegcrc3 58 19 the the DT cord-285647-9tegcrc3 58 20 current current JJ cord-285647-9tegcrc3 58 21 scenario scenario NN cord-285647-9tegcrc3 58 22 . . . cord-285647-9tegcrc3 59 1 We -PRON- PRP cord-285647-9tegcrc3 59 2 start start VBP cord-285647-9tegcrc3 59 3 by by IN cord-285647-9tegcrc3 59 4 mentioning mention VBG cord-285647-9tegcrc3 59 5 that that DT cord-285647-9tegcrc3 60 1 Weiss Weiss NNP cord-285647-9tegcrc3 60 2 et et NNP cord-285647-9tegcrc3 60 3 al al NNP cord-285647-9tegcrc3 60 4 . . . cord-285647-9tegcrc3 61 1 31 31 CD cord-285647-9tegcrc3 61 2 have have VBP cord-285647-9tegcrc3 61 3 analyzed analyze VBN cord-285647-9tegcrc3 61 4 data datum NNS cord-285647-9tegcrc3 61 5 from from IN cord-285647-9tegcrc3 61 6 fluorescence fluorescence NN cord-285647-9tegcrc3 61 7 correlation correlation NN cord-285647-9tegcrc3 61 8 spectroscopy spectroscopy NN cord-285647-9tegcrc3 61 9 ( ( -LRB- cord-285647-9tegcrc3 61 10 FCS FCS NNP cord-285647-9tegcrc3 61 11 ) ) -RRB- cord-285647-9tegcrc3 61 12 for for IN cord-285647-9tegcrc3 61 13 studying study VBG cord-285647-9tegcrc3 61 14 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 61 15 biological biological JJ cord-285647-9tegcrc3 61 16 processes process NNS cord-285647-9tegcrc3 61 17 . . . cord-285647-9tegcrc3 62 1 They -PRON- PRP cord-285647-9tegcrc3 62 2 have have VBP cord-285647-9tegcrc3 62 3 , , , cord-285647-9tegcrc3 62 4 for for IN cord-285647-9tegcrc3 62 5 instance instance NN cord-285647-9tegcrc3 62 6 , , , cord-285647-9tegcrc3 62 7 reported report VBD cord-285647-9tegcrc3 62 8 that that IN cord-285647-9tegcrc3 62 9 membrane membrane NN cord-285647-9tegcrc3 62 10 proteins protein NNS cord-285647-9tegcrc3 62 11 move move VBP cord-285647-9tegcrc3 62 12 subdiffusively subdiffusively RB cord-285647-9tegcrc3 62 13 in in IN cord-285647-9tegcrc3 62 14 the the DT cord-285647-9tegcrc3 62 15 endoplasmic endoplasmic NN cord-285647-9tegcrc3 62 16 reticulum reticulum NN cord-285647-9tegcrc3 62 17 and and CC cord-285647-9tegcrc3 62 18 Golgi Golgi NNP cord-285647-9tegcrc3 62 19 apparatus apparatus NN cord-285647-9tegcrc3 62 20 in in IN cord-285647-9tegcrc3 62 21 vivo vivo NN cord-285647-9tegcrc3 62 22 . . . cord-285647-9tegcrc3 63 1 Subdiffusion Subdiffusion NNP cord-285647-9tegcrc3 63 2 of of IN cord-285647-9tegcrc3 63 3 cytoplasmatic cytoplasmatic JJ cord-285647-9tegcrc3 63 4 macromolecules macromolecule NNS cord-285647-9tegcrc3 63 5 was be VBD cord-285647-9tegcrc3 63 6 also also RB cord-285647-9tegcrc3 63 7 reported report VBN cord-285647-9tegcrc3 63 8 by by IN cord-285647-9tegcrc3 63 9 Weiss Weiss NNP cord-285647-9tegcrc3 63 10 et et NNP cord-285647-9tegcrc3 63 11 al al NNP cord-285647-9tegcrc3 63 12 . . . cord-285647-9tegcrc3 64 1 32 32 CD cord-285647-9tegcrc3 64 2 using use VBG cord-285647-9tegcrc3 64 3 FCS FCS NNP cord-285647-9tegcrc3 64 4 . . . cord-285647-9tegcrc3 65 1 Then then RB cord-285647-9tegcrc3 65 2 , , , cord-285647-9tegcrc3 65 3 Guigas Guigas NNP cord-285647-9tegcrc3 65 4 and and CC cord-285647-9tegcrc3 65 5 Weiss Weiss NNP cord-285647-9tegcrc3 65 6 27 27 CD cord-285647-9tegcrc3 65 7 simulated simulate VBD cord-285647-9tegcrc3 65 8 the the DT cord-285647-9tegcrc3 65 9 way way NN cord-285647-9tegcrc3 65 10 in in IN cord-285647-9tegcrc3 65 11 which which WDT cord-285647-9tegcrc3 65 12 the the DT cord-285647-9tegcrc3 65 13 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 65 14 motion motion NN cord-285647-9tegcrc3 65 15 of of IN cord-285647-9tegcrc3 65 16 these these DT cord-285647-9tegcrc3 65 17 particles particle NNS cord-285647-9tegcrc3 65 18 should should MD cord-285647-9tegcrc3 65 19 occur occur VB cord-285647-9tegcrc3 65 20 in in IN cord-285647-9tegcrc3 65 21 a a DT cord-285647-9tegcrc3 65 22 crowded crowded JJ cord-285647-9tegcrc3 65 23 intracellular intracellular JJ cord-285647-9tegcrc3 65 24 fluid fluid NN cord-285647-9tegcrc3 65 25 . . . cord-285647-9tegcrc3 66 1 They -PRON- PRP cord-285647-9tegcrc3 66 2 did do VBD cord-285647-9tegcrc3 66 3 so so RB cord-285647-9tegcrc3 66 4 by by IN cord-285647-9tegcrc3 66 5 assigning assign VBG cord-285647-9tegcrc3 66 6 diffusive diffusive JJ cord-285647-9tegcrc3 66 7 steps step NNS cord-285647-9tegcrc3 66 8 from from IN cord-285647-9tegcrc3 66 9 a a DT cord-285647-9tegcrc3 66 10 Weirstrass Weirstrass NNP cord-285647-9tegcrc3 66 11 - - HYPH cord-285647-9tegcrc3 66 12 Mandelbrot Mandelbrot NNP cord-285647-9tegcrc3 66 13 function function VBP cord-285647-9tegcrc3 66 14 yielding yield VBG cord-285647-9tegcrc3 66 15 a a DT cord-285647-9tegcrc3 66 16 FBM fbm NN cord-285647-9tegcrc3 66 17 . . . cord-285647-9tegcrc3 67 1 They -PRON- PRP cord-285647-9tegcrc3 67 2 stated state VBD cord-285647-9tegcrc3 67 3 that that IN cord-285647-9tegcrc3 67 4 CTRW CTRW NNP cord-285647-9tegcrc3 67 5 was be VBD cord-285647-9tegcrc3 67 6 excluded exclude VBN cord-285647-9tegcrc3 67 7 due due IN cord-285647-9tegcrc3 67 8 to to IN cord-285647-9tegcrc3 67 9 its -PRON- PRP$ cord-285647-9tegcrc3 67 10 Markovian markovian JJ cord-285647-9tegcrc3 67 11 nature nature NN cord-285647-9tegcrc3 67 12 . . . cord-285647-9tegcrc3 68 1 In in IN cord-285647-9tegcrc3 68 2 another another DT cord-285647-9tegcrc3 68 3 work work NN cord-285647-9tegcrc3 68 4 , , , cord-285647-9tegcrc3 68 5 Szymanski Szymanski NNP cord-285647-9tegcrc3 68 6 and and CC cord-285647-9tegcrc3 68 7 Weiss Weiss NNP cord-285647-9tegcrc3 68 8 33 33 CD cord-285647-9tegcrc3 68 9 used use VBD cord-285647-9tegcrc3 68 10 FCS FCS NNP cord-285647-9tegcrc3 68 11 and and CC cord-285647-9tegcrc3 68 12 simulations simulation NNS cord-285647-9tegcrc3 68 13 to to TO cord-285647-9tegcrc3 68 14 analyze analyze VB cord-285647-9tegcrc3 68 15 the the DT cord-285647-9tegcrc3 68 16 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 68 17 motion motion NN cord-285647-9tegcrc3 68 18 of of IN cord-285647-9tegcrc3 68 19 a a DT cord-285647-9tegcrc3 68 20 protein protein NN cord-285647-9tegcrc3 68 21 in in IN cord-285647-9tegcrc3 68 22 a a DT cord-285647-9tegcrc3 68 23 simulated simulated JJ cord-285647-9tegcrc3 68 24 crowded crowded JJ cord-285647-9tegcrc3 68 25 medium medium NN cord-285647-9tegcrc3 68 26 . . . cord-285647-9tegcrc3 69 1 First first RB cord-285647-9tegcrc3 69 2 , , , cord-285647-9tegcrc3 69 3 they -PRON- PRP cord-285647-9tegcrc3 69 4 reported report VBD cord-285647-9tegcrc3 69 5 that that IN cord-285647-9tegcrc3 69 6 crowded crowd VBN cord-285647-9tegcrc3 69 7 - - HYPH cord-285647-9tegcrc3 69 8 induced induce VBN cord-285647-9tegcrc3 69 9 subdiffusion subdiffusion NN cord-285647-9tegcrc3 69 10 is be VBZ cord-285647-9tegcrc3 69 11 consistent consistent JJ cord-285647-9tegcrc3 69 12 with with IN cord-285647-9tegcrc3 69 13 the the DT cord-285647-9tegcrc3 69 14 predictions prediction NNS cord-285647-9tegcrc3 69 15 from from IN cord-285647-9tegcrc3 69 16 FBM FBM NNP cord-285647-9tegcrc3 69 17 or or CC cord-285647-9tegcrc3 69 18 obstructed obstruct VBN cord-285647-9tegcrc3 69 19 ( ( -LRB- cord-285647-9tegcrc3 69 20 percolation percolation NN cord-285647-9tegcrc3 69 21 - - HYPH cord-285647-9tegcrc3 69 22 like like JJ cord-285647-9tegcrc3 69 23 ) ) -RRB- cord-285647-9tegcrc3 69 24 diffusion diffusion NN cord-285647-9tegcrc3 69 25 . . . cord-285647-9tegcrc3 70 1 Second second RB cord-285647-9tegcrc3 70 2 , , , cord-285647-9tegcrc3 70 3 they -PRON- PRP cord-285647-9tegcrc3 70 4 reported report VBD cord-285647-9tegcrc3 70 5 that that IN cord-285647-9tegcrc3 70 6 CTRW CTRW NNP cord-285647-9tegcrc3 70 7 does do VBZ cord-285647-9tegcrc3 70 8 not not RB cord-285647-9tegcrc3 70 9 explain explain VB cord-285647-9tegcrc3 70 10 the the DT cord-285647-9tegcrc3 70 11 experimental experimental JJ cord-285647-9tegcrc3 70 12 results result NNS cord-285647-9tegcrc3 70 13 obtained obtain VBN cord-285647-9tegcrc3 70 14 by by IN cord-285647-9tegcrc3 70 15 FCS FCS NNP cord-285647-9tegcrc3 70 16 and and CC cord-285647-9tegcrc3 70 17 should should MD cord-285647-9tegcrc3 70 18 not not RB cord-285647-9tegcrc3 70 19 be be VB cord-285647-9tegcrc3 70 20 appropriated appropriate VBN cord-285647-9tegcrc3 70 21 for for IN cord-285647-9tegcrc3 70 22 such such JJ cord-285647-9tegcrc3 70 23 processes process NNS cord-285647-9tegcrc3 70 24 . . . cord-285647-9tegcrc3 71 1 The the DT cord-285647-9tegcrc3 71 2 time time NN cord-285647-9tegcrc3 71 3 resolution resolution NN cord-285647-9tegcrc3 71 4 of of IN cord-285647-9tegcrc3 71 5 FCS FCS NNP cord-285647-9tegcrc3 71 6 is be VBZ cord-285647-9tegcrc3 71 7 in in IN cord-285647-9tegcrc3 71 8 the the DT cord-285647-9tegcrc3 71 9 microsecond microsecond NN cord-285647-9tegcrc3 71 10 range range NN cord-285647-9tegcrc3 71 11 , , , cord-285647-9tegcrc3 71 12 i.e. i.e. FW cord-285647-9tegcrc3 71 13 , , , cord-285647-9tegcrc3 71 14 10 10 CD cord-285647-9tegcrc3 71 15 −6 −6 NNP cord-285647-9tegcrc3 71 16 s. s. NNP cord-285647-9tegcrc3 71 17 34 34 CD cord-285647-9tegcrc3 72 1 However however RB cord-285647-9tegcrc3 72 2 , , , cord-285647-9tegcrc3 72 3 an an DT cord-285647-9tegcrc3 72 4 important important JJ cord-285647-9tegcrc3 72 5 question question NN cord-285647-9tegcrc3 72 6 on on IN cord-285647-9tegcrc3 72 7 biological biological JJ cord-285647-9tegcrc3 72 8 subdiffusion subdiffusion NN cord-285647-9tegcrc3 72 9 may may MD cord-285647-9tegcrc3 72 10 require require VB cord-285647-9tegcrc3 72 11 higher high JJR cord-285647-9tegcrc3 72 12 time time NN cord-285647-9tegcrc3 72 13 resolution resolution NN cord-285647-9tegcrc3 72 14 to to TO cord-285647-9tegcrc3 72 15 be be VB cord-285647-9tegcrc3 72 16 solved solve VBN cord-285647-9tegcrc3 72 17 . . . cord-285647-9tegcrc3 73 1 This this DT cord-285647-9tegcrc3 73 2 is be VBZ cord-285647-9tegcrc3 73 3 the the DT cord-285647-9tegcrc3 73 4 question question NN cord-285647-9tegcrc3 73 5 of of IN cord-285647-9tegcrc3 73 6 how how WRB cord-285647-9tegcrc3 73 7 diffusive diffusive JJ cord-285647-9tegcrc3 73 8 processes process NNS cord-285647-9tegcrc3 73 9 on on IN cord-285647-9tegcrc3 73 10 short short JJ cord-285647-9tegcrc3 73 11 times time NNS cord-285647-9tegcrc3 73 12 , , , cord-285647-9tegcrc3 73 13 while while IN cord-285647-9tegcrc3 73 14 the the DT cord-285647-9tegcrc3 73 15 macromolecule macromolecule NN cord-285647-9tegcrc3 73 16 has have VBZ cord-285647-9tegcrc3 73 17 not not RB cord-285647-9tegcrc3 73 18 felt feel VBN cord-285647-9tegcrc3 73 19 yet yet RB cord-285647-9tegcrc3 73 20 the the DT cord-285647-9tegcrc3 73 21 crowding crowding NN cord-285647-9tegcrc3 73 22 of of IN cord-285647-9tegcrc3 73 23 the the DT cord-285647-9tegcrc3 73 24 environment environment NN cord-285647-9tegcrc3 73 25 , , , cord-285647-9tegcrc3 73 26 is be VBZ cord-285647-9tegcrc3 73 27 related relate VBN cord-285647-9tegcrc3 73 28 to to IN cord-285647-9tegcrc3 73 29 the the DT cord-285647-9tegcrc3 73 30 long long JJ cord-285647-9tegcrc3 73 31 - - HYPH cord-285647-9tegcrc3 73 32 time time NN cord-285647-9tegcrc3 73 33 diffusion diffusion NN cord-285647-9tegcrc3 73 34 . . . cord-285647-9tegcrc3 74 1 This this DT cord-285647-9tegcrc3 74 2 particular particular JJ cord-285647-9tegcrc3 74 3 problem problem NN cord-285647-9tegcrc3 74 4 was be VBD cord-285647-9tegcrc3 74 5 explored explore VBN cord-285647-9tegcrc3 74 6 experimentally experimentally RB cord-285647-9tegcrc3 74 7 by by IN cord-285647-9tegcrc3 74 8 Gupta Gupta NNP cord-285647-9tegcrc3 74 9 et et NNP cord-285647-9tegcrc3 74 10 al al NNP cord-285647-9tegcrc3 74 11 . . . cord-285647-9tegcrc3 75 1 35 35 CD cord-285647-9tegcrc3 75 2 by by IN cord-285647-9tegcrc3 75 3 using use VBG cord-285647-9tegcrc3 75 4 state state NN cord-285647-9tegcrc3 75 5 - - HYPH cord-285647-9tegcrc3 75 6 of of IN cord-285647-9tegcrc3 75 7 - - HYPH cord-285647-9tegcrc3 75 8 the the DT cord-285647-9tegcrc3 75 9 - - HYPH cord-285647-9tegcrc3 75 10 art art NN cord-285647-9tegcrc3 75 11 neutron neutron NN cord-285647-9tegcrc3 75 12 Chaos Chaos NNP cord-285647-9tegcrc3 75 13 ARTICLE article NN cord-285647-9tegcrc3 75 14 scitation.org/journal/cha scitation.org/journal/cha `` cord-285647-9tegcrc3 75 15 spin spin NN cord-285647-9tegcrc3 75 16 - - HYPH cord-285647-9tegcrc3 75 17 echo echo NN cord-285647-9tegcrc3 75 18 ( ( -LRB- cord-285647-9tegcrc3 75 19 NSE NSE NNP cord-285647-9tegcrc3 75 20 ) ) -RRB- cord-285647-9tegcrc3 75 21 and and CC cord-285647-9tegcrc3 75 22 small small JJ cord-285647-9tegcrc3 75 23 - - HYPH cord-285647-9tegcrc3 75 24 angle angle NN cord-285647-9tegcrc3 75 25 neutron neutron NN cord-285647-9tegcrc3 75 26 scattering scattering NN cord-285647-9tegcrc3 75 27 ( ( -LRB- cord-285647-9tegcrc3 75 28 SANS SANS NNP cord-285647-9tegcrc3 75 29 ) ) -RRB- cord-285647-9tegcrc3 75 30 , , , cord-285647-9tegcrc3 75 31 which which WDT cord-285647-9tegcrc3 75 32 has have VBZ cord-285647-9tegcrc3 75 33 a a DT cord-285647-9tegcrc3 75 34 resolution resolution NN cord-285647-9tegcrc3 75 35 in in IN cord-285647-9tegcrc3 75 36 the the DT cord-285647-9tegcrc3 75 37 nanosecond nanosecond NN cord-285647-9tegcrc3 75 38 range range NN cord-285647-9tegcrc3 75 39 , , , cord-285647-9tegcrc3 75 40 i.e. i.e. FW cord-285647-9tegcrc3 75 41 , , , cord-285647-9tegcrc3 75 42 10 10 CD cord-285647-9tegcrc3 75 43 −9 −9 NNP cord-285647-9tegcrc3 75 44 s. s. NN cord-285647-9tegcrc3 76 1 Their -PRON- PRP$ cord-285647-9tegcrc3 76 2 experimental experimental JJ cord-285647-9tegcrc3 76 3 setting setting NN cord-285647-9tegcrc3 76 4 was be VBD cord-285647-9tegcrc3 76 5 defined define VBN cord-285647-9tegcrc3 76 6 by by IN cord-285647-9tegcrc3 76 7 the the DT cord-285647-9tegcrc3 76 8 use use NN cord-285647-9tegcrc3 76 9 of of IN cord-285647-9tegcrc3 76 10 two two CD cord-285647-9tegcrc3 76 11 globular globular JJ cord-285647-9tegcrc3 76 12 proteins protein NNS cord-285647-9tegcrc3 76 13 in in IN cord-285647-9tegcrc3 76 14 a a DT cord-285647-9tegcrc3 76 15 crowded crowded JJ cord-285647-9tegcrc3 76 16 environment environment NN cord-285647-9tegcrc3 76 17 formed form VBN cord-285647-9tegcrc3 76 18 by by IN cord-285647-9tegcrc3 76 19 poly(ethylene poly(ethylene JJ cord-285647-9tegcrc3 76 20 oxide oxide NN cord-285647-9tegcrc3 76 21 ) ) -RRB- cord-285647-9tegcrc3 76 22 ( ( -LRB- cord-285647-9tegcrc3 76 23 PEO PEO NNP cord-285647-9tegcrc3 76 24 ) ) -RRB- cord-285647-9tegcrc3 76 25 , , , cord-285647-9tegcrc3 76 26 which which WDT cord-285647-9tegcrc3 76 27 mimics mimic VBZ cord-285647-9tegcrc3 76 28 a a DT cord-285647-9tegcrc3 76 29 macromolecular macromolecular JJ cord-285647-9tegcrc3 76 30 environment environment NN cord-285647-9tegcrc3 76 31 . . . cord-285647-9tegcrc3 77 1 In in IN cord-285647-9tegcrc3 77 2 their -PRON- PRP$ cord-285647-9tegcrc3 77 3 experiments experiment NNS cord-285647-9tegcrc3 77 4 , , , cord-285647-9tegcrc3 77 5 NSE NSE NNP cord-285647-9tegcrc3 77 6 was be VBD cord-285647-9tegcrc3 77 7 used use VBN cord-285647-9tegcrc3 77 8 to to TO cord-285647-9tegcrc3 77 9 tackle tackle VB cord-285647-9tegcrc3 77 10 the the DT cord-285647-9tegcrc3 77 11 fast fast JJ cord-285647-9tegcrc3 77 12 diffusion diffusion NN cord-285647-9tegcrc3 77 13 process process NN cord-285647-9tegcrc3 77 14 , , , cord-285647-9tegcrc3 77 15 which which WDT cord-285647-9tegcrc3 77 16 corresponds correspond VBZ cord-285647-9tegcrc3 77 17 to to IN cord-285647-9tegcrc3 77 18 a a DT cord-285647-9tegcrc3 77 19 dynamics dynamic NNS cord-285647-9tegcrc3 77 20 inside inside IN cord-285647-9tegcrc3 77 21 a a DT cord-285647-9tegcrc3 77 22 trap trap NN cord-285647-9tegcrc3 77 23 built build VBN cord-285647-9tegcrc3 77 24 by by IN cord-285647-9tegcrc3 77 25 the the DT cord-285647-9tegcrc3 77 26 environment environment NN cord-285647-9tegcrc3 77 27 mesh mesh NN cord-285647-9tegcrc3 77 28 . . . cord-285647-9tegcrc3 78 1 SANS sans NN cord-285647-9tegcrc3 78 2 captures capture VBZ cord-285647-9tegcrc3 78 3 the the DT cord-285647-9tegcrc3 78 4 slow slow JJ cord-285647-9tegcrc3 78 5 dynamics dynamic NNS cord-285647-9tegcrc3 78 6 , , , cord-285647-9tegcrc3 78 7 which which WDT cord-285647-9tegcrc3 78 8 corresponds correspond VBZ cord-285647-9tegcrc3 78 9 to to IN cord-285647-9tegcrc3 78 10 the the DT cord-285647-9tegcrc3 78 11 long long JJ cord-285647-9tegcrc3 78 12 - - HYPH cord-285647-9tegcrc3 78 13 time time NN cord-285647-9tegcrc3 78 14 diffusion diffusion NN cord-285647-9tegcrc3 78 15 at at IN cord-285647-9tegcrc3 78 16 macroscopic macroscopic JJ cord-285647-9tegcrc3 78 17 length length NN cord-285647-9tegcrc3 78 18 scales scale NNS cord-285647-9tegcrc3 78 19 . . . cord-285647-9tegcrc3 79 1 From from IN cord-285647-9tegcrc3 79 2 our -PRON- PRP$ cord-285647-9tegcrc3 79 3 current current JJ cord-285647-9tegcrc3 79 4 perspective perspective NN cord-285647-9tegcrc3 79 5 , , , cord-285647-9tegcrc3 79 6 the the DT cord-285647-9tegcrc3 79 7 most most RBS cord-285647-9tegcrc3 79 8 important important JJ cord-285647-9tegcrc3 79 9 result result NN cord-285647-9tegcrc3 79 10 of of IN cord-285647-9tegcrc3 79 11 this this DT cord-285647-9tegcrc3 79 12 work work NN cord-285647-9tegcrc3 79 13 is be VBZ cord-285647-9tegcrc3 79 14 that that IN cord-285647-9tegcrc3 79 15 the the DT cord-285647-9tegcrc3 79 16 authors author NNS cord-285647-9tegcrc3 79 17 found find VBD cord-285647-9tegcrc3 79 18 that that IN cord-285647-9tegcrc3 79 19 in in IN cord-285647-9tegcrc3 79 20 a a DT cord-285647-9tegcrc3 79 21 higher high JJR cord-285647-9tegcrc3 79 22 concentration concentration NN cord-285647-9tegcrc3 79 23 of of IN cord-285647-9tegcrc3 79 24 polymeric polymeric JJ cord-285647-9tegcrc3 79 25 solutions solution NNS cord-285647-9tegcrc3 79 26 , , , cord-285647-9tegcrc3 79 27 like like IN cord-285647-9tegcrc3 79 28 in in IN cord-285647-9tegcrc3 79 29 the the DT cord-285647-9tegcrc3 79 30 intracellular intracellular JJ cord-285647-9tegcrc3 79 31 space space NN cord-285647-9tegcrc3 79 32 , , , cord-285647-9tegcrc3 79 33 the the DT cord-285647-9tegcrc3 79 34 diffusion diffusion NN cord-285647-9tegcrc3 79 35 is be VBZ cord-285647-9tegcrc3 79 36 fractional fractional JJ cord-285647-9tegcrc3 79 37 in in IN cord-285647-9tegcrc3 79 38 nature nature NN cord-285647-9tegcrc3 79 39 . . . cord-285647-9tegcrc3 80 1 They -PRON- PRP cord-285647-9tegcrc3 80 2 showed show VBD cord-285647-9tegcrc3 80 3 this this DT cord-285647-9tegcrc3 80 4 by by IN cord-285647-9tegcrc3 80 5 using use VBG cord-285647-9tegcrc3 80 6 the the DT cord-285647-9tegcrc3 80 7 fractional fractional JJ cord-285647-9tegcrc3 80 8 Fokker Fokker NNP cord-285647-9tegcrc3 80 9 - - HYPH cord-285647-9tegcrc3 80 10 Planck Planck NNP cord-285647-9tegcrc3 80 11 equation equation NN cord-285647-9tegcrc3 80 12 with with IN cord-285647-9tegcrc3 80 13 a a DT cord-285647-9tegcrc3 80 14 periodic periodic JJ cord-285647-9tegcrc3 80 15 potential potential NN cord-285647-9tegcrc3 80 16 . . . cord-285647-9tegcrc3 81 1 According accord VBG cord-285647-9tegcrc3 81 2 to to IN cord-285647-9tegcrc3 81 3 Gupta Gupta NNP cord-285647-9tegcrc3 81 4 et et NNP cord-285647-9tegcrc3 81 5 al al NNP cord-285647-9tegcrc3 81 6 . . NNP cord-285647-9tegcrc3 81 7 , , , cord-285647-9tegcrc3 81 8 35 35 CD cord-285647-9tegcrc3 81 9 this this DT cord-285647-9tegcrc3 81 10 fractional fractional JJ cord-285647-9tegcrc3 81 11 nature nature NN cord-285647-9tegcrc3 81 12 of of IN cord-285647-9tegcrc3 81 13 the the DT cord-285647-9tegcrc3 81 14 crossover crossover NN cord-285647-9tegcrc3 81 15 from from IN cord-285647-9tegcrc3 81 16 fast fast JJ cord-285647-9tegcrc3 81 17 dynamics dynamic NNS cord-285647-9tegcrc3 81 18 to to TO cord-285647-9tegcrc3 81 19 slow slow VB cord-285647-9tegcrc3 81 20 macroscopic macroscopic JJ cord-285647-9tegcrc3 81 21 dynamics dynamic NNS cord-285647-9tegcrc3 81 22 is be VBZ cord-285647-9tegcrc3 81 23 due due JJ cord-285647-9tegcrc3 81 24 to to IN cord-285647-9tegcrc3 81 25 the the DT cord-285647-9tegcrc3 81 26 heterogeneity heterogeneity NN cord-285647-9tegcrc3 81 27 of of IN cord-285647-9tegcrc3 81 28 the the DT cord-285647-9tegcrc3 81 29 polymer polymer NN cord-285647-9tegcrc3 81 30 mesh mesh NN cord-285647-9tegcrc3 81 31 in in IN cord-285647-9tegcrc3 81 32 the the DT cord-285647-9tegcrc3 81 33 bulk bulk JJ cord-285647-9tegcrc3 81 34 sample sample NN cord-285647-9tegcrc3 81 35 , , , cord-285647-9tegcrc3 81 36 which which WDT cord-285647-9tegcrc3 81 37 may may MD cord-285647-9tegcrc3 81 38 well well RB cord-285647-9tegcrc3 81 39 resemble resemble VB cord-285647-9tegcrc3 81 40 the the DT cord-285647-9tegcrc3 81 41 intra intra JJ cord-285647-9tegcrc3 81 42 - - JJ cord-285647-9tegcrc3 81 43 cellular cellular JJ cord-285647-9tegcrc3 81 44 environment environment NN cord-285647-9tegcrc3 81 45 . . . cord-285647-9tegcrc3 82 1 As as IN cord-285647-9tegcrc3 82 2 proved prove VBN cord-285647-9tegcrc3 82 3 by by IN cord-285647-9tegcrc3 82 4 Barkai Barkai NNP cord-285647-9tegcrc3 82 5 et et NNP cord-285647-9tegcrc3 82 6 al al NNP cord-285647-9tegcrc3 82 7 . . NNP cord-285647-9tegcrc3 82 8 , , , cord-285647-9tegcrc3 82 9 36 36 CD cord-285647-9tegcrc3 82 10 the the DT cord-285647-9tegcrc3 82 11 fractional fractional JJ cord-285647-9tegcrc3 82 12 Fokker Fokker NNP cord-285647-9tegcrc3 82 13 - - HYPH cord-285647-9tegcrc3 82 14 Planck Planck NNP cord-285647-9tegcrc3 82 15 equation equation NN cord-285647-9tegcrc3 82 16 can can MD cord-285647-9tegcrc3 82 17 be be VB cord-285647-9tegcrc3 82 18 derived derive VBN cord-285647-9tegcrc3 82 19 from from IN cord-285647-9tegcrc3 82 20 the the DT cord-285647-9tegcrc3 82 21 CTRW CTRW NNP cord-285647-9tegcrc3 82 22 , , , cord-285647-9tegcrc3 82 23 which which WDT cord-285647-9tegcrc3 82 24 clearly clearly RB cord-285647-9tegcrc3 82 25 indicates indicate VBZ cord-285647-9tegcrc3 82 26 that that IN cord-285647-9tegcrc3 82 27 the the DT cord-285647-9tegcrc3 82 28 results result NNS cord-285647-9tegcrc3 82 29 obtained obtain VBN cord-285647-9tegcrc3 82 30 by by IN cord-285647-9tegcrc3 82 31 Gupta Gupta NNP cord-285647-9tegcrc3 82 32 et et NNP cord-285647-9tegcrc3 82 33 al al NNP cord-285647-9tegcrc3 82 34 . . . cord-285647-9tegcrc3 82 35 point point NN cord-285647-9tegcrc3 82 36 out out RP cord-285647-9tegcrc3 82 37 to to IN cord-285647-9tegcrc3 82 38 the the DT cord-285647-9tegcrc3 82 39 classification classification NN cord-285647-9tegcrc3 82 40 of of IN cord-285647-9tegcrc3 82 41 the the DT cord-285647-9tegcrc3 82 42 subdiffusive subdiffusive NNP cord-285647-9tegcrc3 82 43 dynamics dynamic NNS cord-285647-9tegcrc3 82 44 into into IN cord-285647-9tegcrc3 82 45 the the DT cord-285647-9tegcrc3 82 46 class class NN cord-285647-9tegcrc3 82 47 ( ( -LRB- cord-285647-9tegcrc3 82 48 i i NN cord-285647-9tegcrc3 82 49 ) ) -RRB- cord-285647-9tegcrc3 82 50 . . . cord-285647-9tegcrc3 83 1 We -PRON- PRP cord-285647-9tegcrc3 83 2 should should MD cord-285647-9tegcrc3 83 3 remark remark VB cord-285647-9tegcrc3 83 4 that that IN cord-285647-9tegcrc3 83 5 independently independently RB cord-285647-9tegcrc3 83 6 of of IN cord-285647-9tegcrc3 83 7 these these DT cord-285647-9tegcrc3 83 8 results result NNS cord-285647-9tegcrc3 83 9 by by IN cord-285647-9tegcrc3 83 10 Gupta Gupta NNP cord-285647-9tegcrc3 83 11 et et NNP cord-285647-9tegcrc3 83 12 al al NNP cord-285647-9tegcrc3 83 13 . . . cord-285647-9tegcrc3 84 1 , , , cord-285647-9tegcrc3 84 2 35 35 CD cord-285647-9tegcrc3 84 3 Shorten shorten VB cord-285647-9tegcrc3 84 4 and and CC cord-285647-9tegcrc3 84 5 Sneyd Sneyd NNP cord-285647-9tegcrc3 84 6 37 37 CD cord-285647-9tegcrc3 84 7 have have VBP cord-285647-9tegcrc3 84 8 successfully successfully RB cord-285647-9tegcrc3 84 9 used use VBN cord-285647-9tegcrc3 84 10 the the DT cord-285647-9tegcrc3 84 11 fractional fractional JJ cord-285647-9tegcrc3 84 12 diffusion diffusion NN cord-285647-9tegcrc3 84 13 equation equation NN cord-285647-9tegcrc3 84 14 to to TO cord-285647-9tegcrc3 84 15 mimic mimic VB cord-285647-9tegcrc3 84 16 the the DT cord-285647-9tegcrc3 84 17 protein protein NN cord-285647-9tegcrc3 84 18 diffusion diffusion NN cord-285647-9tegcrc3 84 19 in in IN cord-285647-9tegcrc3 84 20 an an DT cord-285647-9tegcrc3 84 21 obstructed obstruct VBN cord-285647-9tegcrc3 84 22 media medium NNS cord-285647-9tegcrc3 84 23 like like IN cord-285647-9tegcrc3 84 24 within within IN cord-285647-9tegcrc3 84 25 skeletal skeletal JJ cord-285647-9tegcrc3 84 26 muscle muscle NN cord-285647-9tegcrc3 84 27 . . . cord-285647-9tegcrc3 85 1 We -PRON- PRP cord-285647-9tegcrc3 85 2 notice notice VBP cord-285647-9tegcrc3 85 3 in in IN cord-285647-9tegcrc3 85 4 passing pass VBG cord-285647-9tegcrc3 85 5 that that IN cord-285647-9tegcrc3 85 6 the the DT cord-285647-9tegcrc3 85 7 ( ( -LRB- cord-285647-9tegcrc3 85 8 fractional fractional JJ cord-285647-9tegcrc3 85 9 ) ) -RRB- cord-285647-9tegcrc3 85 10 diffusion diffusion NN cord-285647-9tegcrc3 85 11 equation equation NN cord-285647-9tegcrc3 85 12 can can MD cord-285647-9tegcrc3 85 13 be be VB cord-285647-9tegcrc3 85 14 obtained obtain VBN cord-285647-9tegcrc3 85 15 from from IN cord-285647-9tegcrc3 85 16 the the DT cord-285647-9tegcrc3 85 17 ( ( -LRB- cord-285647-9tegcrc3 85 18 fractional fractional JJ cord-285647-9tegcrc3 85 19 ) ) -RRB- cord-285647-9tegcrc3 85 20 Fokker Fokker NNP cord-285647-9tegcrc3 85 21 - - HYPH cord-285647-9tegcrc3 85 22 Planck Planck NNP cord-285647-9tegcrc3 85 23 equation equation NN cord-285647-9tegcrc3 85 24 in in IN cord-285647-9tegcrc3 85 25 the the DT cord-285647-9tegcrc3 85 26 absence absence NN cord-285647-9tegcrc3 85 27 of of IN cord-285647-9tegcrc3 85 28 an an DT cord-285647-9tegcrc3 85 29 external external JJ cord-285647-9tegcrc3 85 30 force force NN cord-285647-9tegcrc3 85 31 . . . cord-285647-9tegcrc3 86 1 In in IN cord-285647-9tegcrc3 86 2 closing closing NN cord-285647-9tegcrc3 86 3 , , , cord-285647-9tegcrc3 86 4 because because IN cord-285647-9tegcrc3 86 5 here here RB cord-285647-9tegcrc3 86 6 we -PRON- PRP cord-285647-9tegcrc3 86 7 are be VBP cord-285647-9tegcrc3 86 8 interested interested JJ cord-285647-9tegcrc3 86 9 in in IN cord-285647-9tegcrc3 86 10 modeling model VBG cord-285647-9tegcrc3 86 11 the the DT cord-285647-9tegcrc3 86 12 diffusion diffusion NN cord-285647-9tegcrc3 86 13 of of IN cord-285647-9tegcrc3 86 14 proteins protein NNS cord-285647-9tegcrc3 86 15 in in IN cord-285647-9tegcrc3 86 16 several several JJ cord-285647-9tegcrc3 86 17 human human JJ cord-285647-9tegcrc3 86 18 cells cell NNS cord-285647-9tegcrc3 86 19 , , , cord-285647-9tegcrc3 86 20 which which WDT cord-285647-9tegcrc3 86 21 are be VBP cord-285647-9tegcrc3 86 22 highly highly RB cord-285647-9tegcrc3 86 23 crowded crowded JJ cord-285647-9tegcrc3 86 24 , , , cord-285647-9tegcrc3 86 25 and and CC cord-285647-9tegcrc3 86 26 in in IN cord-285647-9tegcrc3 86 27 which which WDT cord-285647-9tegcrc3 86 28 we -PRON- PRP cord-285647-9tegcrc3 86 29 should should MD cord-285647-9tegcrc3 86 30 recover recover VB cord-285647-9tegcrc3 86 31 the the DT cord-285647-9tegcrc3 86 32 same same JJ cord-285647-9tegcrc3 86 33 crossover crossover NN cord-285647-9tegcrc3 86 34 between between IN cord-285647-9tegcrc3 86 35 initial initial JJ cord-285647-9tegcrc3 86 36 fast fast NN cord-285647-9tegcrc3 86 37 and and CC cord-285647-9tegcrc3 86 38 later later RB cord-285647-9tegcrc3 86 39 slow slow JJ cord-285647-9tegcrc3 86 40 dynamics dynamic NNS cord-285647-9tegcrc3 86 41 , , , cord-285647-9tegcrc3 86 42 we -PRON- PRP cord-285647-9tegcrc3 86 43 will will MD cord-285647-9tegcrc3 86 44 consider consider VB cord-285647-9tegcrc3 86 45 a a DT cord-285647-9tegcrc3 86 46 modeling modeling NN cord-285647-9tegcrc3 86 47 tool tool NN cord-285647-9tegcrc3 86 48 of of IN cord-285647-9tegcrc3 86 49 the the DT cord-285647-9tegcrc3 86 50 class class NN cord-285647-9tegcrc3 86 51 ( ( -LRB- cord-285647-9tegcrc3 86 52 i i NN cord-285647-9tegcrc3 86 53 ) ) -RRB- cord-285647-9tegcrc3 86 54 . . . cord-285647-9tegcrc3 87 1 In in IN cord-285647-9tegcrc3 87 2 particular particular JJ cord-285647-9tegcrc3 87 3 , , , cord-285647-9tegcrc3 87 4 we -PRON- PRP cord-285647-9tegcrc3 87 5 will will MD cord-285647-9tegcrc3 87 6 focus focus VB cord-285647-9tegcrc3 87 7 our -PRON- PRP$ cord-285647-9tegcrc3 87 8 modeling modeling NN cord-285647-9tegcrc3 87 9 on on IN cord-285647-9tegcrc3 87 10 the the DT cord-285647-9tegcrc3 87 11 use use NN cord-285647-9tegcrc3 87 12 of of IN cord-285647-9tegcrc3 87 13 a a DT cord-285647-9tegcrc3 87 14 time time NN cord-285647-9tegcrc3 87 15 - - HYPH cord-285647-9tegcrc3 87 16 fractional fractional JJ cord-285647-9tegcrc3 87 17 diffusion diffusion NN cord-285647-9tegcrc3 87 18 equation equation NN cord-285647-9tegcrc3 87 19 using use VBG cord-285647-9tegcrc3 87 20 Caputo Caputo NNP cord-285647-9tegcrc3 87 21 derivatives derivative NNS cord-285647-9tegcrc3 87 22 . . . cord-285647-9tegcrc3 88 1 Another another DT cord-285647-9tegcrc3 88 2 justification justification NN cord-285647-9tegcrc3 88 3 for for IN cord-285647-9tegcrc3 88 4 the the DT cord-285647-9tegcrc3 88 5 use use NN cord-285647-9tegcrc3 88 6 of of IN cord-285647-9tegcrc3 88 7 this this DT cord-285647-9tegcrc3 88 8 model model NN cord-285647-9tegcrc3 88 9 here here RB cord-285647-9tegcrc3 88 10 is be VBZ cord-285647-9tegcrc3 88 11 that that IN cord-285647-9tegcrc3 88 12 interacting interact VBG cord-285647-9tegcrc3 88 13 proteins protein NNS cord-285647-9tegcrc3 88 14 can can MD cord-285647-9tegcrc3 88 15 be be VB cord-285647-9tegcrc3 88 16 in in IN cord-285647-9tegcrc3 88 17 different different JJ cord-285647-9tegcrc3 88 18 kinds kind NNS cord-285647-9tegcrc3 88 19 of of IN cord-285647-9tegcrc3 88 20 cells cell NNS cord-285647-9tegcrc3 88 21 . . . cord-285647-9tegcrc3 89 1 Thus thus RB cord-285647-9tegcrc3 89 2 , , , cord-285647-9tegcrc3 89 3 we -PRON- PRP cord-285647-9tegcrc3 89 4 consider consider VBP cord-285647-9tegcrc3 89 5 that that IN cord-285647-9tegcrc3 89 6 the the DT cord-285647-9tegcrc3 89 7 perturbation perturbation NN cord-285647-9tegcrc3 89 8 of of IN cord-285647-9tegcrc3 89 9 one one CD cord-285647-9tegcrc3 89 10 protein protein NN cord-285647-9tegcrc3 89 11 is be VBZ cord-285647-9tegcrc3 89 12 not not RB cord-285647-9tegcrc3 89 13 necessarily necessarily RB cord-285647-9tegcrc3 89 14 followed follow VBN cord-285647-9tegcrc3 89 15 by by IN cord-285647-9tegcrc3 89 16 the the DT cord-285647-9tegcrc3 89 17 perturbation perturbation NN cord-285647-9tegcrc3 89 18 of of IN cord-285647-9tegcrc3 89 19 one one CD cord-285647-9tegcrc3 89 20 of of IN cord-285647-9tegcrc3 89 21 its -PRON- PRP$ cord-285647-9tegcrc3 89 22 interactors interactor NNS cord-285647-9tegcrc3 89 23 , , , cord-285647-9tegcrc3 89 24 but but CC cord-285647-9tegcrc3 89 25 a a DT cord-285647-9tegcrc3 89 26 time time NN cord-285647-9tegcrc3 89 27 may may MD cord-285647-9tegcrc3 89 28 mediate mediate VB cord-285647-9tegcrc3 89 29 between between IN cord-285647-9tegcrc3 89 30 the the DT cord-285647-9tegcrc3 89 31 two two CD cord-285647-9tegcrc3 89 32 processes process NNS cord-285647-9tegcrc3 89 33 . . . cord-285647-9tegcrc3 90 1 This this DT cord-285647-9tegcrc3 90 2 is be VBZ cord-285647-9tegcrc3 90 3 exactly exactly RB cord-285647-9tegcrc3 90 4 the the DT cord-285647-9tegcrc3 90 5 kind kind NN cord-285647-9tegcrc3 90 6 of of IN cord-285647-9tegcrc3 90 7 processes process NNS cord-285647-9tegcrc3 90 8 that that WDT cord-285647-9tegcrc3 90 9 the the DT cord-285647-9tegcrc3 90 10 time time NN cord-285647-9tegcrc3 90 11 - - HYPH cord-285647-9tegcrc3 90 12 fractional fractional JJ cord-285647-9tegcrc3 90 13 diffusion diffusion NN cord-285647-9tegcrc3 90 14 captures capture VBZ cord-285647-9tegcrc3 90 15 . . . cord-285647-9tegcrc3 91 1 In in IN cord-285647-9tegcrc3 91 2 this this DT cord-285647-9tegcrc3 91 3 work work NN cord-285647-9tegcrc3 91 4 , , , cord-285647-9tegcrc3 91 5 we -PRON- PRP cord-285647-9tegcrc3 91 6 always always RB cord-285647-9tegcrc3 91 7 consider consider VBP cord-285647-9tegcrc3 91 8 G g NN cord-285647-9tegcrc3 91 9 = = NFP cord-285647-9tegcrc3 91 10 ( ( -LRB- cord-285647-9tegcrc3 91 11 V v NN cord-285647-9tegcrc3 91 12 , , , cord-285647-9tegcrc3 91 13 E E NNP cord-285647-9tegcrc3 91 14 ) ) -RRB- cord-285647-9tegcrc3 91 15 to to TO cord-285647-9tegcrc3 91 16 be be VB cord-285647-9tegcrc3 91 17 an an DT cord-285647-9tegcrc3 91 18 undirected undirected JJ cord-285647-9tegcrc3 91 19 finite finite JJ cord-285647-9tegcrc3 91 20 network network NN cord-285647-9tegcrc3 91 21 with with IN cord-285647-9tegcrc3 91 22 vertices vertex NNS cord-285647-9tegcrc3 91 23 V V NNP cord-285647-9tegcrc3 91 24 representing represent VBG cord-285647-9tegcrc3 91 25 proteins protein NNS cord-285647-9tegcrc3 91 26 and and CC cord-285647-9tegcrc3 91 27 edges edge VBZ cord-285647-9tegcrc3 91 28 E E NNP cord-285647-9tegcrc3 91 29 representing represent VBG cord-285647-9tegcrc3 91 30 the the DT cord-285647-9tegcrc3 91 31 interaction interaction NN cord-285647-9tegcrc3 91 32 between between IN cord-285647-9tegcrc3 91 33 pairs pair NNS cord-285647-9tegcrc3 91 34 of of IN cord-285647-9tegcrc3 91 35 proteins protein NNS cord-285647-9tegcrc3 91 36 . . . cord-285647-9tegcrc3 92 1 Let let VB cord-285647-9tegcrc3 92 2 us -PRON- PRP cord-285647-9tegcrc3 92 3 consider consider VB cord-285647-9tegcrc3 92 4 0 0 NFP cord-285647-9tegcrc3 92 5 < < XX cord-285647-9tegcrc3 92 6 α α NN cord-285647-9tegcrc3 92 7 ≤ ≤ NN cord-285647-9tegcrc3 92 8 1 1 CD cord-285647-9tegcrc3 92 9 and and CC cord-285647-9tegcrc3 92 10 a a DT cord-285647-9tegcrc3 92 11 function function NN cord-285647-9tegcrc3 92 12 u u NN cord-285647-9tegcrc3 92 13 : : : cord-285647-9tegcrc3 92 14 [ [ -LRB- cord-285647-9tegcrc3 92 15 0 0 NFP cord-285647-9tegcrc3 92 16 , , , cord-285647-9tegcrc3 92 17 ∞ ∞ NNP cord-285647-9tegcrc3 92 18 ) ) -RRB- cord-285647-9tegcrc3 92 19 → → WDT cord-285647-9tegcrc3 92 20 R r NN cord-285647-9tegcrc3 92 21 , , , cord-285647-9tegcrc3 92 22 then then RB cord-285647-9tegcrc3 92 23 we -PRON- PRP cord-285647-9tegcrc3 92 24 denote denote VBP cord-285647-9tegcrc3 92 25 by by IN cord-285647-9tegcrc3 92 26 D d NN cord-285647-9tegcrc3 92 27 α α NN cord-285647-9tegcrc3 92 28 t t NN cord-285647-9tegcrc3 92 29 u u NNP cord-285647-9tegcrc3 92 30 the the DT cord-285647-9tegcrc3 92 31 fractional fractional JJ cord-285647-9tegcrc3 92 32 Caputo Caputo NNP cord-285647-9tegcrc3 92 33 derivative derivative NN cord-285647-9tegcrc3 92 34 of of IN cord-285647-9tegcrc3 92 35 u u NN cord-285647-9tegcrc3 92 36 of of IN cord-285647-9tegcrc3 92 37 the the DT cord-285647-9tegcrc3 92 38 order order NN cord-285647-9tegcrc3 92 39 α α NN cord-285647-9tegcrc3 92 40 , , , cord-285647-9tegcrc3 92 41 which which WDT cord-285647-9tegcrc3 92 42 is be VBZ cord-285647-9tegcrc3 92 43 given give VBN cord-285647-9tegcrc3 92 44 by by IN cord-285647-9tegcrc3 92 45 38 38 CD cord-285647-9tegcrc3 92 46 where where WRB cord-285647-9tegcrc3 92 47 * * NFP cord-285647-9tegcrc3 92 48 denotes denote VBZ cord-285647-9tegcrc3 92 49 the the DT cord-285647-9tegcrc3 92 50 classical classical JJ cord-285647-9tegcrc3 92 51 convolution convolution NN cord-285647-9tegcrc3 92 52 product product NN cord-285647-9tegcrc3 92 53 on on IN cord-285647-9tegcrc3 92 54 ( ( -LRB- cord-285647-9tegcrc3 92 55 0 0 CD cord-285647-9tegcrc3 92 56 , , , cord-285647-9tegcrc3 92 57 ∞ ∞ NNP cord-285647-9tegcrc3 92 58 ) ) -RRB- cord-285647-9tegcrc3 92 59 and and CC cord-285647-9tegcrc3 92 60 g g NN cord-285647-9tegcrc3 92 61 γ γ NN cord-285647-9tegcrc3 92 62 ( ( -LRB- cord-285647-9tegcrc3 92 63 t t NN cord-285647-9tegcrc3 92 64 ) ) -RRB- cord-285647-9tegcrc3 92 65 t t NN cord-285647-9tegcrc3 92 66 γ γ NNP cord-285647-9tegcrc3 92 67 −1 −1 NNP cord-285647-9tegcrc3 92 68 ( ( -LRB- cord-285647-9tegcrc3 92 69 γ γ NNP cord-285647-9tegcrc3 92 70 ) ) -RRB- cord-285647-9tegcrc3 92 71 , , , cord-285647-9tegcrc3 92 72 for for IN cord-285647-9tegcrc3 92 73 γ γ NN cord-285647-9tegcrc3 92 74 > > XX cord-285647-9tegcrc3 92 75 0,where 0,where , cord-285647-9tegcrc3 92 76 ( ( -LRB- cord-285647-9tegcrc3 92 77 · · NFP cord-285647-9tegcrc3 92 78 ) ) -RRB- cord-285647-9tegcrc3 92 79 is be VBZ cord-285647-9tegcrc3 92 80 the the DT cord-285647-9tegcrc3 92 81 Euler Euler NNP cord-285647-9tegcrc3 92 82 gamma gamma NN cord-285647-9tegcrc3 92 83 function function NN cord-285647-9tegcrc3 92 84 . . . cord-285647-9tegcrc3 93 1 Observe observe VB cord-285647-9tegcrc3 93 2 that that IN cord-285647-9tegcrc3 93 3 the the DT cord-285647-9tegcrc3 93 4 previous previous JJ cord-285647-9tegcrc3 93 5 fractional fractional JJ cord-285647-9tegcrc3 93 6 derivative derivative NN cord-285647-9tegcrc3 93 7 has have VBZ cord-285647-9tegcrc3 93 8 sense sense NN cord-285647-9tegcrc3 93 9 whenever whenever WRB cord-285647-9tegcrc3 93 10 the the DT cord-285647-9tegcrc3 93 11 function function NN cord-285647-9tegcrc3 93 12 is be VBZ cord-285647-9tegcrc3 93 13 derivable derivable JJ cord-285647-9tegcrc3 93 14 and and CC cord-285647-9tegcrc3 93 15 the the DT cord-285647-9tegcrc3 93 16 convolution convolution NN cord-285647-9tegcrc3 93 17 is be VBZ cord-285647-9tegcrc3 93 18 defined define VBN cord-285647-9tegcrc3 93 19 ( ( -LRB- cord-285647-9tegcrc3 93 20 for for IN cord-285647-9tegcrc3 93 21 example example NN cord-285647-9tegcrc3 93 22 , , , cord-285647-9tegcrc3 93 23 if if IN cord-285647-9tegcrc3 93 24 u u NNP cord-285647-9tegcrc3 93 25 is be VBZ cord-285647-9tegcrc3 93 26 locally locally RB cord-285647-9tegcrc3 93 27 integrable integrable JJ cord-285647-9tegcrc3 93 28 ) ) -RRB- cord-285647-9tegcrc3 93 29 . . . cord-285647-9tegcrc3 94 1 The the DT cord-285647-9tegcrc3 94 2 notation notation NN cord-285647-9tegcrc3 94 3 g g NN cord-285647-9tegcrc3 94 4 γ γ NN cord-285647-9tegcrc3 94 5 is be VBZ cord-285647-9tegcrc3 94 6 very very RB cord-285647-9tegcrc3 94 7 useful useful JJ cord-285647-9tegcrc3 94 8 in in IN cord-285647-9tegcrc3 94 9 the the DT cord-285647-9tegcrc3 94 10 fractional fractional JJ cord-285647-9tegcrc3 94 11 calculus calculus NN cord-285647-9tegcrc3 94 12 theory theory NN cord-285647-9tegcrc3 94 13 , , , cord-285647-9tegcrc3 94 14 mainly mainly RB cord-285647-9tegcrc3 94 15 by by IN cord-285647-9tegcrc3 94 16 the the DT cord-285647-9tegcrc3 94 17 property property NN cord-285647-9tegcrc3 94 18 g g NN cord-285647-9tegcrc3 94 19 γ γ NN cord-285647-9tegcrc3 94 20 * * NFP cord-285647-9tegcrc3 94 21 g g NN cord-285647-9tegcrc3 94 22 δ δ NN cord-285647-9tegcrc3 94 23 = = SYM cord-285647-9tegcrc3 94 24 g g NN cord-285647-9tegcrc3 94 25 γ γ NN cord-285647-9tegcrc3 94 26 + + CC cord-285647-9tegcrc3 94 27 δ δ NN cord-285647-9tegcrc3 94 28 for for IN cord-285647-9tegcrc3 94 29 all all DT cord-285647-9tegcrc3 94 30 γ γ XX cord-285647-9tegcrc3 94 31 , , , cord-285647-9tegcrc3 95 1 δ δ NN cord-285647-9tegcrc3 95 2 > > XX cord-285647-9tegcrc3 95 3 0 0 NFP cord-285647-9tegcrc3 95 4 . . . cord-285647-9tegcrc3 96 1 Here here RB cord-285647-9tegcrc3 96 2 , , , cord-285647-9tegcrc3 96 3 we -PRON- PRP cord-285647-9tegcrc3 96 4 propose propose VBP cord-285647-9tegcrc3 96 5 to to TO cord-285647-9tegcrc3 96 6 consider consider VB cord-285647-9tegcrc3 96 7 the the DT cord-285647-9tegcrc3 96 8 time time NN cord-285647-9tegcrc3 96 9 - - HYPH cord-285647-9tegcrc3 96 10 fractional fractional NN cord-285647-9tegcrc3 96 11 diffusion diffusion NN cord-285647-9tegcrc3 96 12 ( ( -LRB- cord-285647-9tegcrc3 96 13 TFD TFD NNP cord-285647-9tegcrc3 96 14 ) ) -RRB- cord-285647-9tegcrc3 96 15 equation equation NN cord-285647-9tegcrc3 96 16 on on IN cord-285647-9tegcrc3 96 17 the the DT cord-285647-9tegcrc3 96 18 network network NN cord-285647-9tegcrc3 96 19 as as IN cord-285647-9tegcrc3 96 20 with with IN cord-285647-9tegcrc3 96 21 the the DT cord-285647-9tegcrc3 96 22 initial initial JJ cord-285647-9tegcrc3 96 23 condition condition NN cord-285647-9tegcrc3 97 1 x x LS cord-285647-9tegcrc3 97 2 ( ( -LRB- cord-285647-9tegcrc3 97 3 0 0 NFP cord-285647-9tegcrc3 97 4 ) ) -RRB- cord-285647-9tegcrc3 98 1 = = NFP cord-285647-9tegcrc3 99 1 x x LS cord-285647-9tegcrc3 99 2 0 0 CD cord-285647-9tegcrc3 99 3 , , , cord-285647-9tegcrc3 99 4 where where WRB cord-285647-9tegcrc3 99 5 x x NN cord-285647-9tegcrc3 99 6 i i PRP cord-285647-9tegcrc3 99 7 ( ( -LRB- cord-285647-9tegcrc3 99 8 t t NN cord-285647-9tegcrc3 99 9 ) ) -RRB- cord-285647-9tegcrc3 99 10 is be VBZ cord-285647-9tegcrc3 99 11 the the DT cord-285647-9tegcrc3 99 12 probability probability NN cord-285647-9tegcrc3 99 13 that that IN cord-285647-9tegcrc3 99 14 the the DT cord-285647-9tegcrc3 99 15 protein protein NN cord-285647-9tegcrc3 99 16 i i PRP cord-285647-9tegcrc3 99 17 is be VBZ cord-285647-9tegcrc3 99 18 perturbed perturb VBN cord-285647-9tegcrc3 99 19 at at IN cord-285647-9tegcrc3 99 20 the the DT cord-285647-9tegcrc3 99 21 time time NN cord-285647-9tegcrc3 99 22 t t NN cord-285647-9tegcrc3 100 1 ; ; : cord-285647-9tegcrc3 100 2 C C NNP cord-285647-9tegcrc3 100 3 is be VBZ cord-285647-9tegcrc3 100 4 the the DT cord-285647-9tegcrc3 100 5 diffusion diffusion NN cord-285647-9tegcrc3 100 6 coefficient coefficient NN cord-285647-9tegcrc3 100 7 of of IN cord-285647-9tegcrc3 100 8 the the DT cord-285647-9tegcrc3 100 9 network network NN cord-285647-9tegcrc3 100 10 , , , cord-285647-9tegcrc3 100 11 which which WDT cord-285647-9tegcrc3 100 12 we -PRON- PRP cord-285647-9tegcrc3 100 13 will will MD cord-285647-9tegcrc3 100 14 set set VB cord-285647-9tegcrc3 100 15 hereafter hereafter RB cord-285647-9tegcrc3 100 16 to to IN cord-285647-9tegcrc3 100 17 unity unity NN cord-285647-9tegcrc3 100 18 ; ; : cord-285647-9tegcrc3 100 19 and and CC cord-285647-9tegcrc3 100 20 L L NNP cord-285647-9tegcrc3 100 21 is be VBZ cord-285647-9tegcrc3 100 22 the the DT cord-285647-9tegcrc3 100 23 graph graph NN cord-285647-9tegcrc3 100 24 Laplacian Laplacian NNP cord-285647-9tegcrc3 100 25 , , , cord-285647-9tegcrc3 100 26 i.e. i.e. FW cord-285647-9tegcrc3 100 27 , , , cord-285647-9tegcrc3 100 28 L l NN cord-285647-9tegcrc3 100 29 = = NFP cord-285647-9tegcrc3 101 1 K K NNP cord-285647-9tegcrc3 101 2 − − NNP cord-285647-9tegcrc3 101 3 A A NNP cord-285647-9tegcrc3 101 4 , , , cord-285647-9tegcrc3 101 5 where where WRB cord-285647-9tegcrc3 101 6 K K NNP cord-285647-9tegcrc3 101 7 is be VBZ cord-285647-9tegcrc3 101 8 a a DT cord-285647-9tegcrc3 101 9 diagonal diagonal JJ cord-285647-9tegcrc3 101 10 matrix matrix NN cord-285647-9tegcrc3 101 11 of of IN cord-285647-9tegcrc3 101 12 node node NN cord-285647-9tegcrc3 101 13 degrees degree NNS cord-285647-9tegcrc3 101 14 and and CC cord-285647-9tegcrc3 101 15 A a NN cord-285647-9tegcrc3 101 16 is be VBZ cord-285647-9tegcrc3 101 17 the the DT cord-285647-9tegcrc3 101 18 adjacency adjacency NN cord-285647-9tegcrc3 101 19 matrix matrix NN cord-285647-9tegcrc3 101 20 . . . cord-285647-9tegcrc3 102 1 This this DT cord-285647-9tegcrc3 102 2 model model NN cord-285647-9tegcrc3 102 3 was be VBD cord-285647-9tegcrc3 102 4 previously previously RB cord-285647-9tegcrc3 102 5 studied study VBN cord-285647-9tegcrc3 102 6 in in IN cord-285647-9tegcrc3 102 7 distributed distribute VBN cord-285647-9tegcrc3 102 8 coordination coordination NN cord-285647-9tegcrc3 102 9 algorithms algorithm NNS cord-285647-9tegcrc3 102 10 for for IN cord-285647-9tegcrc3 102 11 the the DT cord-285647-9tegcrc3 102 12 consensus consensus NN cord-285647-9tegcrc3 102 13 of of IN cord-285647-9tegcrc3 102 14 multi multi JJ cord-285647-9tegcrc3 102 15 - - JJ cord-285647-9tegcrc3 102 16 agent agent JJ cord-285647-9tegcrc3 102 17 systems system NNS cord-285647-9tegcrc3 102 18 . . . cord-285647-9tegcrc3 103 1 [ [ -LRB- cord-285647-9tegcrc3 103 2 39 39 CD cord-285647-9tegcrc3 103 3 ] ] -RRB- cord-285647-9tegcrc3 103 4 [ [ -LRB- cord-285647-9tegcrc3 103 5 40 40 CD cord-285647-9tegcrc3 103 6 ] ] -RRB- cord-285647-9tegcrc3 103 7 [ [ -LRB- cord-285647-9tegcrc3 103 8 41 41 CD cord-285647-9tegcrc3 103 9 ] ] -RRB- cord-285647-9tegcrc3 104 1 The the DT cord-285647-9tegcrc3 104 2 use use NN cord-285647-9tegcrc3 104 3 of of IN cord-285647-9tegcrc3 104 4 fractional fractional JJ cord-285647-9tegcrc3 104 5 calculus calculus NN cord-285647-9tegcrc3 104 6 in in IN cord-285647-9tegcrc3 104 7 the the DT cord-285647-9tegcrc3 104 8 context context NN cord-285647-9tegcrc3 104 9 of of IN cord-285647-9tegcrc3 104 10 physical physical JJ cord-285647-9tegcrc3 104 11 anomalous anomalous JJ cord-285647-9tegcrc3 104 12 diffusion diffusion NN cord-285647-9tegcrc3 104 13 has have VBZ cord-285647-9tegcrc3 104 14 been be VBN cord-285647-9tegcrc3 104 15 reviewed review VBN cord-285647-9tegcrc3 104 16 by by IN cord-285647-9tegcrc3 104 17 Metzler Metzler NNP cord-285647-9tegcrc3 104 18 and and CC cord-285647-9tegcrc3 104 19 Klafter Klafter NNP cord-285647-9tegcrc3 104 20 . . . cord-285647-9tegcrc3 105 1 42 42 CD cord-285647-9tegcrc3 106 1 A a DT cord-285647-9tegcrc3 106 2 different different JJ cord-285647-9tegcrc3 106 3 approach approach NN cord-285647-9tegcrc3 106 4 has have VBZ cord-285647-9tegcrc3 106 5 been be VBN cord-285647-9tegcrc3 106 6 developed develop VBN cord-285647-9tegcrc3 106 7 by by IN cord-285647-9tegcrc3 106 8 Riascos Riascos NNP cord-285647-9tegcrc3 106 9 and and CC cord-285647-9tegcrc3 106 10 Mateos Mateos NNP cord-285647-9tegcrc3 106 11 . . . cord-285647-9tegcrc3 107 1 43 43 CD cord-285647-9tegcrc3 107 2 , , , cord-285647-9tegcrc3 107 3 44 44 CD cord-285647-9tegcrc3 108 1 It -PRON- PRP cord-285647-9tegcrc3 108 2 is be VBZ cord-285647-9tegcrc3 108 3 based base VBN cord-285647-9tegcrc3 108 4 on on IN cord-285647-9tegcrc3 108 5 the the DT cord-285647-9tegcrc3 108 6 use use NN cord-285647-9tegcrc3 108 7 of of IN cord-285647-9tegcrc3 108 8 fractional fractional JJ cord-285647-9tegcrc3 108 9 powers power NNS cord-285647-9tegcrc3 108 10 of of IN cord-285647-9tegcrc3 108 11 the the DT cord-285647-9tegcrc3 108 12 graph graph NN cord-285647-9tegcrc3 108 13 Laplacian Laplacian NNP cord-285647-9tegcrc3 108 14 ( ( -LRB- cord-285647-9tegcrc3 108 15 see see VB cord-285647-9tegcrc3 108 16 Ref Ref NNP cord-285647-9tegcrc3 108 17 . . . cord-285647-9tegcrc3 109 1 45 45 CD cord-285647-9tegcrc3 109 2 and and CC cord-285647-9tegcrc3 109 3 references reference NNS cord-285647-9tegcrc3 109 4 therein therein RB cord-285647-9tegcrc3 109 5 ) ) -RRB- cord-285647-9tegcrc3 109 6 . . . cord-285647-9tegcrc3 110 1 The the DT cord-285647-9tegcrc3 110 2 approach approach NN cord-285647-9tegcrc3 110 3 has have VBZ cord-285647-9tegcrc3 110 4 been be VBN cord-285647-9tegcrc3 110 5 recently recently RB cord-285647-9tegcrc3 110 6 formalized formalize VBN cord-285647-9tegcrc3 110 7 by by IN cord-285647-9tegcrc3 110 8 Benzi Benzi NNP cord-285647-9tegcrc3 110 9 et et NNP cord-285647-9tegcrc3 110 10 al al NNP cord-285647-9tegcrc3 110 11 . . . cord-285647-9tegcrc3 111 1 46 46 CD cord-285647-9tegcrc3 112 1 This this DT cord-285647-9tegcrc3 112 2 method method NN cord-285647-9tegcrc3 112 3 can can MD cord-285647-9tegcrc3 112 4 not not RB cord-285647-9tegcrc3 112 5 be be VB cord-285647-9tegcrc3 112 6 used use VBN cord-285647-9tegcrc3 112 7 in in IN cord-285647-9tegcrc3 112 8 the the DT cord-285647-9tegcrc3 112 9 current current JJ cord-285647-9tegcrc3 112 10 framework framework NN cord-285647-9tegcrc3 112 11 because because IN cord-285647-9tegcrc3 112 12 it -PRON- PRP cord-285647-9tegcrc3 112 13 generates generate VBZ cord-285647-9tegcrc3 112 14 only only RB cord-285647-9tegcrc3 112 15 superdiffusive superdiffusive JJ cord-285647-9tegcrc3 112 16 behaviors behavior NNS cord-285647-9tegcrc3 112 17 ( ( -LRB- cord-285647-9tegcrc3 112 18 see see VB cord-285647-9tegcrc3 112 19 Benzi Benzi NNP cord-285647-9tegcrc3 112 20 et et NNP cord-285647-9tegcrc3 112 21 al al NNP cord-285647-9tegcrc3 112 22 . . . cord-285647-9tegcrc3 113 1 46 46 LS cord-285647-9tegcrc3 113 2 ) ) -RRB- cord-285647-9tegcrc3 113 3 and and CC cord-285647-9tegcrc3 113 4 not not RB cord-285647-9tegcrc3 113 5 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 113 6 regimes regime NNS cord-285647-9tegcrc3 113 7 . . . cord-285647-9tegcrc3 114 1 Another another DT cord-285647-9tegcrc3 114 2 disadvantage disadvantage NN cord-285647-9tegcrc3 114 3 of of IN cord-285647-9tegcrc3 114 4 this this DT cord-285647-9tegcrc3 114 5 approach approach NN cord-285647-9tegcrc3 114 6 is be VBZ cord-285647-9tegcrc3 114 7 that that IN cord-285647-9tegcrc3 114 8 it -PRON- PRP cord-285647-9tegcrc3 114 9 can can MD cord-285647-9tegcrc3 114 10 only only RB cord-285647-9tegcrc3 114 11 be be VB cord-285647-9tegcrc3 114 12 used use VBN cord-285647-9tegcrc3 114 13 to to IN cord-285647-9tegcrc3 114 14 positive positive JJ cord-285647-9tegcrc3 114 15 ( ( -LRB- cord-285647-9tegcrc3 114 16 semi)definite semi)definite NNP cord-285647-9tegcrc3 114 17 graph graph NN cord-285647-9tegcrc3 114 18 operators operator NNS cord-285647-9tegcrc3 114 19 , , , cord-285647-9tegcrc3 114 20 such such JJ cord-285647-9tegcrc3 114 21 as as IN cord-285647-9tegcrc3 114 22 the the DT cord-285647-9tegcrc3 114 23 Laplacian Laplacian NNP cord-285647-9tegcrc3 114 24 , , , cord-285647-9tegcrc3 114 25 but but CC cord-285647-9tegcrc3 114 26 not not RB cord-285647-9tegcrc3 114 27 to to TO cord-285647-9tegcrc3 114 28 adjacency adjacency NN cord-285647-9tegcrc3 114 29 operators operator NNS cord-285647-9tegcrc3 114 30 such such JJ cord-285647-9tegcrc3 114 31 as as IN cord-285647-9tegcrc3 114 32 the the DT cord-285647-9tegcrc3 114 33 one one NN cord-285647-9tegcrc3 114 34 used use VBN cord-285647-9tegcrc3 114 35 in in IN cord-285647-9tegcrc3 114 36 tight tight RB cord-285647-9tegcrc3 114 37 - - HYPH cord-285647-9tegcrc3 114 38 binding bind VBG cord-285647-9tegcrc3 114 39 quantum quantum NN cord-285647-9tegcrc3 114 40 mechanical mechanical JJ cord-285647-9tegcrc3 114 41 or or CC cord-285647-9tegcrc3 114 42 epidemiological epidemiological JJ cord-285647-9tegcrc3 114 43 approaches approach NNS cord-285647-9tegcrc3 114 44 ( ( -LRB- cord-285647-9tegcrc3 114 45 see see VB cord-285647-9tegcrc3 114 46 Sec Sec NNP cord-285647-9tegcrc3 114 47 . . . cord-285647-9tegcrc3 114 48 VI VI NNP cord-285647-9tegcrc3 114 49 ) ) -RRB- cord-285647-9tegcrc3 114 50 . . . cord-285647-9tegcrc3 115 1 Theorem theorem NN cord-285647-9tegcrc3 115 2 1 1 CD cord-285647-9tegcrc3 115 3 . . . cord-285647-9tegcrc3 116 1 The the DT cord-285647-9tegcrc3 116 2 solution solution NN cord-285647-9tegcrc3 116 3 of of IN cord-285647-9tegcrc3 116 4 the the DT cord-285647-9tegcrc3 116 5 fractional fractional JJ cord-285647-9tegcrc3 116 6 - - HYPH cord-285647-9tegcrc3 116 7 time time NN cord-285647-9tegcrc3 116 8 diffusion diffusion NN cord-285647-9tegcrc3 116 9 model model NN cord-285647-9tegcrc3 116 10 on on IN cord-285647-9tegcrc3 116 11 the the DT cord-285647-9tegcrc3 116 12 network network NN cord-285647-9tegcrc3 116 13 is be VBZ cord-285647-9tegcrc3 116 14 where where WRB cord-285647-9tegcrc3 116 15 E E NNP cord-285647-9tegcrc3 116 16 α α NN cord-285647-9tegcrc3 116 17 , , , cord-285647-9tegcrc3 116 18 β β NN cord-285647-9tegcrc3 116 19 ( ( -LRB- cord-285647-9tegcrc3 116 20 γ γ NNP cord-285647-9tegcrc3 116 21 L L NNP cord-285647-9tegcrc3 116 22 ) ) -RRB- cord-285647-9tegcrc3 116 23 is be VBZ cord-285647-9tegcrc3 116 24 the the DT cord-285647-9tegcrc3 116 25 Mittag Mittag NNP cord-285647-9tegcrc3 116 26 - - HYPH cord-285647-9tegcrc3 116 27 Leffler Leffler NNP cord-285647-9tegcrc3 116 28 function function NN cord-285647-9tegcrc3 116 29 of of IN cord-285647-9tegcrc3 116 30 the the DT cord-285647-9tegcrc3 116 31 Laplacian Laplacian NNP cord-285647-9tegcrc3 116 32 matrix matrix NN cord-285647-9tegcrc3 116 33 of of IN cord-285647-9tegcrc3 116 34 a a DT cord-285647-9tegcrc3 116 35 graph graph NN cord-285647-9tegcrc3 116 36 . . . cord-285647-9tegcrc3 117 1 Proof proof NN cord-285647-9tegcrc3 117 2 . . . cord-285647-9tegcrc3 118 1 We -PRON- PRP cord-285647-9tegcrc3 118 2 use use VBP cord-285647-9tegcrc3 118 3 the the DT cord-285647-9tegcrc3 118 4 spectral spectral JJ cord-285647-9tegcrc3 118 5 decomposition decomposition NN cord-285647-9tegcrc3 118 6 of of IN cord-285647-9tegcrc3 118 7 the the DT cord-285647-9tegcrc3 118 8 network network NN cord-285647-9tegcrc3 118 9 Laplacian Laplacian NNP cord-285647-9tegcrc3 118 10 L L NNP cord-285647-9tegcrc3 118 11 = = SYM cord-285647-9tegcrc3 118 12 UΛU UΛU NNP cord-285647-9tegcrc3 118 13 −1 −1 NNP cord-285647-9tegcrc3 118 14 , , , cord-285647-9tegcrc3 118 15 where where WRB cord-285647-9tegcrc3 118 16 U U NNP cord-285647-9tegcrc3 118 17 = = SYM cord-285647-9tegcrc3 118 18 ψ ψ NN cord-285647-9tegcrc3 118 19 1 1 CD cord-285647-9tegcrc3 118 20 · · NFP cord-285647-9tegcrc3 118 21 · · NFP cord-285647-9tegcrc3 118 22 · · NFP cord-285647-9tegcrc3 118 23 ψ ψ NN cord-285647-9tegcrc3 118 24 n n NN cord-285647-9tegcrc3 118 25 and and CC cord-285647-9tegcrc3 118 26 Λ Λ NNP cord-285647-9tegcrc3 118 27 = = SYM cord-285647-9tegcrc3 118 28 diag diag NNP cord-285647-9tegcrc3 118 29 ( ( -LRB- cord-285647-9tegcrc3 118 30 µ µ NNP cord-285647-9tegcrc3 118 31 r r NNP cord-285647-9tegcrc3 118 32 ) ) -RRB- cord-285647-9tegcrc3 118 33 . . . cord-285647-9tegcrc3 119 1 Then then RB cord-285647-9tegcrc3 119 2 , , , cord-285647-9tegcrc3 119 3 we -PRON- PRP cord-285647-9tegcrc3 119 4 can can MD cord-285647-9tegcrc3 119 5 write write VB cord-285647-9tegcrc3 119 6 Let let VB cord-285647-9tegcrc3 119 7 us -PRON- PRP cord-285647-9tegcrc3 119 8 define define VB cord-285647-9tegcrc3 119 9 y y NNP cord-285647-9tegcrc3 119 10 ( ( -LRB- cord-285647-9tegcrc3 119 11 t t NN cord-285647-9tegcrc3 119 12 ) ) -RRB- cord-285647-9tegcrc3 120 1 = = NFP cord-285647-9tegcrc3 121 1 U U NNP cord-285647-9tegcrc3 122 1 −1 −1 NNP cord-285647-9tegcrc3 122 2 x x NNP cord-285647-9tegcrc3 122 3 ( ( -LRB- cord-285647-9tegcrc3 122 4 t t NN cord-285647-9tegcrc3 122 5 ) ) -RRB- cord-285647-9tegcrc3 122 6 such such JJ cord-285647-9tegcrc3 122 7 that that IN cord-285647-9tegcrc3 122 8 D d NN cord-285647-9tegcrc3 122 9 α α NN cord-285647-9tegcrc3 123 1 t t NNP cord-285647-9tegcrc3 123 2 x x NNP cord-285647-9tegcrc3 123 3 ( ( -LRB- cord-285647-9tegcrc3 123 4 t t NN cord-285647-9tegcrc3 123 5 ) ) -RRB- cord-285647-9tegcrc3 123 6 = = NFP cord-285647-9tegcrc3 124 1 −UΛy −UΛy NNP cord-285647-9tegcrc3 124 2 ( ( -LRB- cord-285647-9tegcrc3 124 3 t t NN cord-285647-9tegcrc3 124 4 ) ) -RRB- cord-285647-9tegcrc3 124 5 , , . cord-285647-9tegcrc3 125 1 and and CC cord-285647-9tegcrc3 125 2 we -PRON- PRP cord-285647-9tegcrc3 125 3 have have VBP cord-285647-9tegcrc3 126 1 As as IN cord-285647-9tegcrc3 126 2 is be VBZ cord-285647-9tegcrc3 126 3 a a DT cord-285647-9tegcrc3 126 4 diagonal diagonal JJ cord-285647-9tegcrc3 126 5 matrix matrix NN cord-285647-9tegcrc3 126 6 , , , cord-285647-9tegcrc3 126 7 we -PRON- PRP cord-285647-9tegcrc3 126 8 can can MD cord-285647-9tegcrc3 126 9 write write VB cord-285647-9tegcrc3 126 10 which which WDT cord-285647-9tegcrc3 126 11 has have VBZ cord-285647-9tegcrc3 126 12 the the DT cord-285647-9tegcrc3 126 13 solution solution NN cord-285647-9tegcrc3 126 14 We -PRON- PRP cord-285647-9tegcrc3 126 15 can can MD cord-285647-9tegcrc3 126 16 replace replace VB cord-285647-9tegcrc3 126 17 which which WDT cord-285647-9tegcrc3 126 18 finally finally RB cord-285647-9tegcrc3 126 19 gives give VBZ cord-285647-9tegcrc3 126 20 the the DT cord-285647-9tegcrc3 126 21 result result NN cord-285647-9tegcrc3 126 22 in in IN cord-285647-9tegcrc3 126 23 the the DT cord-285647-9tegcrc3 126 24 matrix matrix NN cord-285647-9tegcrc3 126 25 - - HYPH cord-285647-9tegcrc3 126 26 vector vector NN cord-285647-9tegcrc3 126 27 when when WRB cord-285647-9tegcrc3 126 28 written write VBN cord-285647-9tegcrc3 126 29 for for IN cord-285647-9tegcrc3 126 30 all all PDT cord-285647-9tegcrc3 126 31 the the DT cord-285647-9tegcrc3 126 32 nodes node NNS cord-285647-9tegcrc3 126 33 , , , cord-285647-9tegcrc3 126 34 We -PRON- PRP cord-285647-9tegcrc3 126 35 can can MD cord-285647-9tegcrc3 126 36 write write VB cord-285647-9tegcrc3 126 37 L l NN cord-285647-9tegcrc3 126 38 = = SYM cord-285647-9tegcrc3 126 39 UΛU UΛU NNP cord-285647-9tegcrc3 126 40 −1 −1 NNP cord-285647-9tegcrc3 126 41 , , , cord-285647-9tegcrc3 127 1 where where WRB cord-285647-9tegcrc3 127 2 U U NNP cord-285647-9tegcrc3 127 3 = = SYM cord-285647-9tegcrc3 127 4 ψ ψ NN cord-285647-9tegcrc3 127 5 1 1 CD cord-285647-9tegcrc3 127 6 · · NFP cord-285647-9tegcrc3 127 7 · · NFP cord-285647-9tegcrc3 127 8 · · NFP cord-285647-9tegcrc3 127 9 ψ ψ NN cord-285647-9tegcrc3 127 10 n n NN cord-285647-9tegcrc3 127 11 and and CC cord-285647-9tegcrc3 127 12 Λ Λ NNP cord-285647-9tegcrc3 127 13 = = SYM cord-285647-9tegcrc3 127 14 diag diag NNP cord-285647-9tegcrc3 127 15 ( ( -LRB- cord-285647-9tegcrc3 127 16 µ µ NNP cord-285647-9tegcrc3 127 17 r r NNP cord-285647-9tegcrc3 127 18 ) ) -RRB- cord-285647-9tegcrc3 127 19 . . . cord-285647-9tegcrc3 128 1 Then then RB cord-285647-9tegcrc3 128 2 , , , cord-285647-9tegcrc3 128 3 which which WDT cord-285647-9tegcrc3 128 4 can can MD cord-285647-9tegcrc3 128 5 be be VB cord-285647-9tegcrc3 128 6 expanded expand VBN cord-285647-9tegcrc3 128 7 as as IN cord-285647-9tegcrc3 128 8 where where WRB cord-285647-9tegcrc3 128 9 ψ ψ NNP cord-285647-9tegcrc3 128 10 j j NNP cord-285647-9tegcrc3 128 11 and and CC cord-285647-9tegcrc3 128 12 φ φ NNP cord-285647-9tegcrc3 128 13 j j NNP cord-285647-9tegcrc3 128 14 are be VBP cord-285647-9tegcrc3 128 15 the the DT cord-285647-9tegcrc3 128 16 jth jth NNP cord-285647-9tegcrc3 128 17 column column NN cord-285647-9tegcrc3 128 18 of of IN cord-285647-9tegcrc3 128 19 U U NNP cord-285647-9tegcrc3 128 20 and and CC cord-285647-9tegcrc3 128 21 of of IN cord-285647-9tegcrc3 128 22 U U NNP cord-285647-9tegcrc3 128 23 −1 −1 NNP cord-285647-9tegcrc3 128 24 , , , cord-285647-9tegcrc3 128 25 respectively respectively RB cord-285647-9tegcrc3 128 26 . . . cord-285647-9tegcrc3 129 1 Because because IN cord-285647-9tegcrc3 129 2 µ µ NN cord-285647-9tegcrc3 129 3 1 1 CD cord-285647-9tegcrc3 129 4 = = SYM cord-285647-9tegcrc3 129 5 0 0 CD cord-285647-9tegcrc3 129 6 and and CC cord-285647-9tegcrc3 129 7 0 0 NFP cord-285647-9tegcrc3 129 8 < < XX cord-285647-9tegcrc3 129 9 µ µ NN cord-285647-9tegcrc3 129 10 2 2 CD cord-285647-9tegcrc3 129 11 ≤ ≤ NN cord-285647-9tegcrc3 129 12 · · NFP cord-285647-9tegcrc3 129 13 · · NFP cord-285647-9tegcrc3 129 14 · · NFP cord-285647-9tegcrc3 129 15 ≤ ≤ NN cord-285647-9tegcrc3 129 16 µ µ NNP cord-285647-9tegcrc3 129 17 n n NN cord-285647-9tegcrc3 129 18 for for IN cord-285647-9tegcrc3 129 19 a a DT cord-285647-9tegcrc3 129 20 connected connected JJ cord-285647-9tegcrc3 129 21 graph graph NN cord-285647-9tegcrc3 129 22 , , , cord-285647-9tegcrc3 129 23 we -PRON- PRP cord-285647-9tegcrc3 129 24 have have VBP cord-285647-9tegcrc3 129 25 lim lim NNP cord-285647-9tegcrc3 129 26 where where WRB cord-285647-9tegcrc3 129 27 ψ ψ NN cord-285647-9tegcrc3 129 28 T T NNP cord-285647-9tegcrc3 129 29 1 1 CD cord-285647-9tegcrc3 129 30 φ φ NN cord-285647-9tegcrc3 129 31 1 1 CD cord-285647-9tegcrc3 129 32 = = SYM cord-285647-9tegcrc3 129 33 1 1 CD cord-285647-9tegcrc3 129 34 . . . cord-285647-9tegcrc3 130 1 Let let VB cord-285647-9tegcrc3 130 2 us -PRON- PRP cord-285647-9tegcrc3 130 3 take take VB cord-285647-9tegcrc3 130 4 ψ ψ NN cord-285647-9tegcrc3 130 5 1 1 CD cord-285647-9tegcrc3 130 6 = = SYM cord-285647-9tegcrc3 130 7 1 1 CD cord-285647-9tegcrc3 130 8 , , , cord-285647-9tegcrc3 130 9 such such JJ cord-285647-9tegcrc3 130 10 that that IN cord-285647-9tegcrc3 130 11 we -PRON- PRP cord-285647-9tegcrc3 130 12 have have VBP cord-285647-9tegcrc3 130 13 This this DT cord-285647-9tegcrc3 130 14 result result NN cord-285647-9tegcrc3 130 15 indicates indicate VBZ cord-285647-9tegcrc3 130 16 that that IN cord-285647-9tegcrc3 130 17 in in IN cord-285647-9tegcrc3 130 18 an an DT cord-285647-9tegcrc3 130 19 undirected undirected JJ cord-285647-9tegcrc3 130 20 and and CC cord-285647-9tegcrc3 130 21 connected connected JJ cord-285647-9tegcrc3 130 22 network network NN cord-285647-9tegcrc3 130 23 , , , cord-285647-9tegcrc3 130 24 the the DT cord-285647-9tegcrc3 130 25 diffusive diffusive JJ cord-285647-9tegcrc3 130 26 process process NN cord-285647-9tegcrc3 130 27 controlled control VBN cord-285647-9tegcrc3 130 28 by by IN cord-285647-9tegcrc3 130 29 the the DT cord-285647-9tegcrc3 130 30 TFD TFD NNP cord-285647-9tegcrc3 130 31 equation equation NN cord-285647-9tegcrc3 130 32 always always RB cord-285647-9tegcrc3 130 33 reaches reach VBZ cord-285647-9tegcrc3 130 34 a a DT cord-285647-9tegcrc3 130 35 steady steady JJ cord-285647-9tegcrc3 130 36 state state NN cord-285647-9tegcrc3 130 37 , , , cord-285647-9tegcrc3 130 38 which which WDT cord-285647-9tegcrc3 130 39 consists consist VBZ cord-285647-9tegcrc3 130 40 of of IN cord-285647-9tegcrc3 130 41 the the DT cord-285647-9tegcrc3 130 42 average average NN cord-285647-9tegcrc3 130 43 of of IN cord-285647-9tegcrc3 130 44 the the DT cord-285647-9tegcrc3 130 45 values value NNS cord-285647-9tegcrc3 130 46 of of IN cord-285647-9tegcrc3 130 47 the the DT cord-285647-9tegcrc3 130 48 initial initial JJ cord-285647-9tegcrc3 130 49 condition condition NN cord-285647-9tegcrc3 130 50 . . . cord-285647-9tegcrc3 131 1 In in IN cord-285647-9tegcrc3 131 2 the the DT cord-285647-9tegcrc3 131 3 case case NN cord-285647-9tegcrc3 131 4 of of IN cord-285647-9tegcrc3 131 5 directed direct VBN cord-285647-9tegcrc3 131 6 networks network NNS cord-285647-9tegcrc3 131 7 ( ( -LRB- cord-285647-9tegcrc3 131 8 PPI PPI NNP cord-285647-9tegcrc3 131 9 are be VBP cord-285647-9tegcrc3 131 10 not not RB cord-285647-9tegcrc3 131 11 directed direct VBN cord-285647-9tegcrc3 131 12 by by IN cord-285647-9tegcrc3 131 13 nature nature NN cord-285647-9tegcrc3 131 14 ) ) -RRB- cord-285647-9tegcrc3 131 15 or or CC cord-285647-9tegcrc3 131 16 in in IN cord-285647-9tegcrc3 131 17 disconnected disconnected JJ cord-285647-9tegcrc3 131 18 networks network NNS cord-285647-9tegcrc3 131 19 ( ( -LRB- cord-285647-9tegcrc3 131 20 a a DT cord-285647-9tegcrc3 131 21 situation situation NN cord-285647-9tegcrc3 131 22 that that WDT cord-285647-9tegcrc3 131 23 can can MD cord-285647-9tegcrc3 131 24 be be VB cord-285647-9tegcrc3 131 25 found find VBN cord-285647-9tegcrc3 131 26 in in IN cord-285647-9tegcrc3 131 27 PPIs ppi NNS cord-285647-9tegcrc3 131 28 ) ) -RRB- cord-285647-9tegcrc3 131 29 , , , cord-285647-9tegcrc3 131 30 the the DT cord-285647-9tegcrc3 131 31 steady steady JJ cord-285647-9tegcrc3 131 32 state state NN cord-285647-9tegcrc3 131 33 is be VBZ cord-285647-9tegcrc3 131 34 reached reach VBN cord-285647-9tegcrc3 131 35 in in IN cord-285647-9tegcrc3 131 36 each each DT cord-285647-9tegcrc3 131 37 ( ( -LRB- cord-285647-9tegcrc3 131 38 strongly strongly RB cord-285647-9tegcrc3 131 39 ) ) -RRB- cord-285647-9tegcrc3 131 40 connected connect VBN cord-285647-9tegcrc3 131 41 component component NN cord-285647-9tegcrc3 131 42 of of IN cord-285647-9tegcrc3 131 43 the the DT cord-285647-9tegcrc3 131 44 graph graph NN cord-285647-9tegcrc3 131 45 . . . cord-285647-9tegcrc3 132 1 Also also RB cord-285647-9tegcrc3 132 2 , , , cord-285647-9tegcrc3 132 3 because because IN cord-285647-9tegcrc3 132 4 the the DT cord-285647-9tegcrc3 132 5 network network NN cord-285647-9tegcrc3 132 6 is be VBZ cord-285647-9tegcrc3 132 7 connected connect VBN cord-285647-9tegcrc3 132 8 , , , cord-285647-9tegcrc3 132 9 µ µ NN cord-285647-9tegcrc3 132 10 2 2 CD cord-285647-9tegcrc3 132 11 makes make VBZ cord-285647-9tegcrc3 132 12 the the DT cord-285647-9tegcrc3 132 13 largest large JJS cord-285647-9tegcrc3 132 14 contribution contribution NN cord-285647-9tegcrc3 132 15 to to IN cord-285647-9tegcrc3 132 16 E e NN cord-285647-9tegcrc3 132 17 α,1 α,1 FW cord-285647-9tegcrc3 132 18 ( ( -LRB- cord-285647-9tegcrc3 132 19 −t −t NNP cord-285647-9tegcrc3 132 20 α α NN cord-285647-9tegcrc3 132 21 L l NN cord-285647-9tegcrc3 132 22 ) ) -RRB- cord-285647-9tegcrc3 132 23 among among IN cord-285647-9tegcrc3 132 24 all all PDT cord-285647-9tegcrc3 132 25 the the DT cord-285647-9tegcrc3 132 26 nontrivial nontrivial JJ cord-285647-9tegcrc3 132 27 eigenvalues eigenvalue NNS cord-285647-9tegcrc3 132 28 of of IN cord-285647-9tegcrc3 133 1 L. L. NNP cord-285647-9tegcrc3 133 2 Therefore therefore RB cord-285647-9tegcrc3 133 3 , , , cord-285647-9tegcrc3 133 4 it -PRON- PRP cord-285647-9tegcrc3 133 5 dictates dictate VBZ cord-285647-9tegcrc3 133 6 the the DT cord-285647-9tegcrc3 133 7 rate rate NN cord-285647-9tegcrc3 133 8 of of IN cord-285647-9tegcrc3 133 9 convergence convergence NN cord-285647-9tegcrc3 133 10 of of IN cord-285647-9tegcrc3 133 11 the the DT cord-285647-9tegcrc3 133 12 diffusion diffusion NN cord-285647-9tegcrc3 133 13 process process NN cord-285647-9tegcrc3 133 14 . . . cord-285647-9tegcrc3 134 1 We -PRON- PRP cord-285647-9tegcrc3 134 2 remark remark VBP cord-285647-9tegcrc3 134 3 that that IN cord-285647-9tegcrc3 134 4 in in IN cord-285647-9tegcrc3 134 5 practice practice NN cord-285647-9tegcrc3 134 6 , , , cord-285647-9tegcrc3 134 7 the the DT cord-285647-9tegcrc3 134 8 steady steady JJ cord-285647-9tegcrc3 134 9 state state NN cord-285647-9tegcrc3 134 10 lim lim NNP cord-285647-9tegcrc3 134 11 t→∞ t→∞ NNP cord-285647-9tegcrc3 135 1 x x NN cord-285647-9tegcrc3 135 2 v v LS cord-285647-9tegcrc3 135 3 ( ( -LRB- cord-285647-9tegcrc3 135 4 t t NN cord-285647-9tegcrc3 135 5 ) ) -RRB- cord-285647-9tegcrc3 135 6 − − NNP cord-285647-9tegcrc3 136 1 x x SYM cord-285647-9tegcrc3 136 2 w w NNP cord-285647-9tegcrc3 136 3 ( ( -LRB- cord-285647-9tegcrc3 136 4 t t NN cord-285647-9tegcrc3 136 5 ) ) -RRB- cord-285647-9tegcrc3 136 6 = = SYM cord-285647-9tegcrc3 136 7 0 0 CD cord-285647-9tegcrc3 136 8 , , , cord-285647-9tegcrc3 137 1 ∀v ∀v NNP cord-285647-9tegcrc3 137 2 , , , cord-285647-9tegcrc3 137 3 w w NN cord-285647-9tegcrc3 137 4 ∈ ∈ NN cord-285647-9tegcrc3 137 5 V v NN cord-285647-9tegcrc3 137 6 is be VBZ cord-285647-9tegcrc3 137 7 very very RB cord-285647-9tegcrc3 137 8 difficult difficult JJ cord-285647-9tegcrc3 137 9 to to TO cord-285647-9tegcrc3 137 10 achieve achieve VB cord-285647-9tegcrc3 137 11 . . . cord-285647-9tegcrc3 138 1 Therefore therefore RB cord-285647-9tegcrc3 138 2 , , , cord-285647-9tegcrc3 138 3 we -PRON- PRP cord-285647-9tegcrc3 138 4 use use VBP cord-285647-9tegcrc3 138 5 a a DT cord-285647-9tegcrc3 138 6 threshold threshold NN cord-285647-9tegcrc3 138 7 ε ε NN cord-285647-9tegcrc3 138 8 , , , cord-285647-9tegcrc3 138 9 e.g. e.g. RB cord-285647-9tegcrc3 138 10 , , , cord-285647-9tegcrc3 138 11 ε ε NN cord-285647-9tegcrc3 138 12 = = SYM cord-285647-9tegcrc3 138 13 10 10 CD cord-285647-9tegcrc3 138 14 −3 −3 NN cord-285647-9tegcrc3 138 15 , , , cord-285647-9tegcrc3 138 16 such such JJ cord-285647-9tegcrc3 138 17 that that IN cord-285647-9tegcrc3 138 18 lim lim NNP cord-285647-9tegcrc3 138 19 t→∞ t→∞ NNP cord-285647-9tegcrc3 138 20 x x NNP cord-285647-9tegcrc3 138 21 v v NNP cord-285647-9tegcrc3 138 22 ( ( -LRB- cord-285647-9tegcrc3 138 23 t t NN cord-285647-9tegcrc3 138 24 ) ) -RRB- cord-285647-9tegcrc3 138 25 − − NNP cord-285647-9tegcrc3 139 1 x x SYM cord-285647-9tegcrc3 139 2 w w NNP cord-285647-9tegcrc3 139 3 ( ( -LRB- cord-285647-9tegcrc3 139 4 t t NN cord-285647-9tegcrc3 139 5 ) ) -RRB- cord-285647-9tegcrc3 139 6 = = NFP cord-285647-9tegcrc3 140 1 ε ε NNP cord-285647-9tegcrc3 140 2 is be VBZ cord-285647-9tegcrc3 140 3 achieved achieve VBN cord-285647-9tegcrc3 140 4 in in IN cord-285647-9tegcrc3 140 5 a a DT cord-285647-9tegcrc3 140 6 relatively relatively RB cord-285647-9tegcrc3 140 7 small small JJ cord-285647-9tegcrc3 140 8 simulation simulation NN cord-285647-9tegcrc3 140 9 time time NN cord-285647-9tegcrc3 140 10 . . . cord-285647-9tegcrc3 141 1 Due due IN cord-285647-9tegcrc3 141 2 to to IN cord-285647-9tegcrc3 141 3 its -PRON- PRP$ cord-285647-9tegcrc3 141 4 importance importance NN cord-285647-9tegcrc3 141 5 in in IN cord-285647-9tegcrc3 141 6 this this DT cord-285647-9tegcrc3 141 7 work work NN cord-285647-9tegcrc3 141 8 , , , cord-285647-9tegcrc3 141 9 we -PRON- PRP cord-285647-9tegcrc3 141 10 remark remark VBP cord-285647-9tegcrc3 141 11 the the DT cord-285647-9tegcrc3 141 12 structural structural JJ cord-285647-9tegcrc3 141 13 meaning meaning NN cord-285647-9tegcrc3 141 14 of of IN cord-285647-9tegcrc3 141 15 the the DT cord-285647-9tegcrc3 141 16 Mittag Mittag NNP cord-285647-9tegcrc3 141 17 - - HYPH cord-285647-9tegcrc3 141 18 Leffler Leffler NNP cord-285647-9tegcrc3 141 19 function function NN cord-285647-9tegcrc3 141 20 of of IN cord-285647-9tegcrc3 141 21 the the DT cord-285647-9tegcrc3 141 22 Laplacian Laplacian NNP cord-285647-9tegcrc3 141 23 matrix matrix NN cord-285647-9tegcrc3 141 24 appearing appear VBG cord-285647-9tegcrc3 141 25 in in IN cord-285647-9tegcrc3 141 26 the the DT cord-285647-9tegcrc3 141 27 solution solution NN cord-285647-9tegcrc3 141 28 of of IN cord-285647-9tegcrc3 141 29 the the DT cord-285647-9tegcrc3 141 30 TFD TFD NNP cord-285647-9tegcrc3 141 31 equation equation NN cord-285647-9tegcrc3 141 32 . . . cord-285647-9tegcrc3 142 1 That that DT cord-285647-9tegcrc3 142 2 is is RB cord-285647-9tegcrc3 142 3 , , , cord-285647-9tegcrc3 142 4 E e FW cord-285647-9tegcrc3 142 5 α,1 α,1 FW cord-285647-9tegcrc3 142 6 ( ( -LRB- cord-285647-9tegcrc3 142 7 −t −t NNP cord-285647-9tegcrc3 142 8 α α NNP cord-285647-9tegcrc3 142 9 L l NN cord-285647-9tegcrc3 142 10 ) ) -RRB- cord-285647-9tegcrc3 142 11 is be VBZ cord-285647-9tegcrc3 142 12 a a DT cord-285647-9tegcrc3 142 13 matrix matrix NN cord-285647-9tegcrc3 142 14 function function NN cord-285647-9tegcrc3 142 15 , , , cord-285647-9tegcrc3 142 16 which which WDT cord-285647-9tegcrc3 142 17 is be VBZ cord-285647-9tegcrc3 142 18 defined define VBN cord-285647-9tegcrc3 142 19 as as IN cord-285647-9tegcrc3 142 20 where where WRB cord-285647-9tegcrc3 142 21 ( ( -LRB- cord-285647-9tegcrc3 142 22 · · NFP cord-285647-9tegcrc3 142 23 ) ) -RRB- cord-285647-9tegcrc3 143 1 is be VBZ cord-285647-9tegcrc3 143 2 the the DT cord-285647-9tegcrc3 143 3 Euler Euler NNP cord-285647-9tegcrc3 143 4 gamma gamma NN cord-285647-9tegcrc3 143 5 function function NN cord-285647-9tegcrc3 143 6 as as IN cord-285647-9tegcrc3 143 7 before before RB cord-285647-9tegcrc3 143 8 . . . cord-285647-9tegcrc3 144 1 We -PRON- PRP cord-285647-9tegcrc3 144 2 remark remark VBP cord-285647-9tegcrc3 144 3 that that IN cord-285647-9tegcrc3 144 4 for for IN cord-285647-9tegcrc3 144 5 α α NN cord-285647-9tegcrc3 144 6 = = SYM cord-285647-9tegcrc3 144 7 1 1 CD cord-285647-9tegcrc3 144 8 , , , cord-285647-9tegcrc3 144 9 we -PRON- PRP cord-285647-9tegcrc3 144 10 recover recover VBP cord-285647-9tegcrc3 144 11 the the DT cord-285647-9tegcrc3 144 12 diffusion diffusion NN cord-285647-9tegcrc3 144 13 equation equation NN cord-285647-9tegcrc3 144 14 on on IN cord-285647-9tegcrc3 144 15 the the DT cord-285647-9tegcrc3 144 16 network network NN cord-285647-9tegcrc3 144 17 : : : cord-285647-9tegcrc3 145 1 dx dx NNP cord-285647-9tegcrc3 145 2 ( ( -LRB- cord-285647-9tegcrc3 145 3 t t NN cord-285647-9tegcrc3 145 4 ) ) -RRB- cord-285647-9tegcrc3 146 1 /dt /dt . cord-285647-9tegcrc3 147 1 = = NFP cord-285647-9tegcrc3 148 1 −Lx −Lx NNP cord-285647-9tegcrc3 148 2 ( ( -LRB- cord-285647-9tegcrc3 148 3 t t NNP cord-285647-9tegcrc3 148 4 ) ) -RRB- cord-285647-9tegcrc3 148 5 and and CC cord-285647-9tegcrc3 149 1 its -PRON- PRP$ cord-285647-9tegcrc3 149 2 solution solution NN cord-285647-9tegcrc3 149 3 E e NN cord-285647-9tegcrc3 149 4 1,1 1,1 CD cord-285647-9tegcrc3 149 5 ( ( -LRB- cord-285647-9tegcrc3 149 6 −t −t NNP cord-285647-9tegcrc3 149 7 α α NNP cord-285647-9tegcrc3 149 8 L l NN cord-285647-9tegcrc3 149 9 ) ) -RRB- cord-285647-9tegcrc3 149 10 = = SYM cord-285647-9tegcrc3 149 11 exp exp NNP cord-285647-9tegcrc3 149 12 ( ( -LRB- cord-285647-9tegcrc3 149 13 −tCL −tCL NNP cord-285647-9tegcrc3 149 14 ) ) -RRB- cord-285647-9tegcrc3 149 15 is be VBZ cord-285647-9tegcrc3 149 16 the the DT cord-285647-9tegcrc3 149 17 well well RB cord-285647-9tegcrc3 149 18 - - HYPH cord-285647-9tegcrc3 149 19 known know VBN cord-285647-9tegcrc3 149 20 heat heat NN cord-285647-9tegcrc3 149 21 kernel kernel NN cord-285647-9tegcrc3 149 22 of of IN cord-285647-9tegcrc3 149 23 the the DT cord-285647-9tegcrc3 149 24 graph graph NN cord-285647-9tegcrc3 149 25 . . . cord-285647-9tegcrc3 150 1 We -PRON- PRP cord-285647-9tegcrc3 150 2 define define VBP cord-285647-9tegcrc3 150 3 here here RB cord-285647-9tegcrc3 150 4 a a DT cord-285647-9tegcrc3 150 5 generalization generalization NN cord-285647-9tegcrc3 150 6 of of IN cord-285647-9tegcrc3 150 7 the the DT cord-285647-9tegcrc3 150 8 diffusion diffusion NN cord-285647-9tegcrc3 150 9 distance distance NN cord-285647-9tegcrc3 150 10 studied study VBN cord-285647-9tegcrc3 150 11 by by IN cord-285647-9tegcrc3 150 12 Coifman Coifman NNP cord-285647-9tegcrc3 150 13 and and CC cord-285647-9tegcrc3 150 14 Lafon Lafon NNP cord-285647-9tegcrc3 150 15 . . . cord-285647-9tegcrc3 151 1 47 47 CD cord-285647-9tegcrc3 151 2 _SP cord-285647-9tegcrc3 152 1 Then then RB cord-285647-9tegcrc3 152 2 , , , cord-285647-9tegcrc3 152 3 we -PRON- PRP cord-285647-9tegcrc3 152 4 define define VBP cord-285647-9tegcrc3 152 5 the the DT cord-285647-9tegcrc3 152 6 following following JJ cord-285647-9tegcrc3 152 7 quantity quantity NN cord-285647-9tegcrc3 152 8 : : : cord-285647-9tegcrc3 152 9 We -PRON- PRP cord-285647-9tegcrc3 152 10 have have VBP cord-285647-9tegcrc3 152 11 the the DT cord-285647-9tegcrc3 152 12 following following JJ cord-285647-9tegcrc3 152 13 result result NN cord-285647-9tegcrc3 152 14 . . . cord-285647-9tegcrc3 153 1 Proof proof NN cord-285647-9tegcrc3 153 2 . . . cord-285647-9tegcrc3 154 1 The the DT cord-285647-9tegcrc3 154 2 matrix matrix NN cord-285647-9tegcrc3 154 3 function function NN cord-285647-9tegcrc3 154 4 f f NNP cord-285647-9tegcrc3 154 5 ( ( -LRB- cord-285647-9tegcrc3 154 6 τ τ NN cord-285647-9tegcrc3 154 7 L l NN cord-285647-9tegcrc3 154 8 ) ) -RRB- cord-285647-9tegcrc3 154 9 can can MD cord-285647-9tegcrc3 154 10 be be VB cord-285647-9tegcrc3 154 11 written write VBN cord-285647-9tegcrc3 154 12 as as IN cord-285647-9tegcrc3 154 13 f f NNP cord-285647-9tegcrc3 154 14 ( ( -LRB- cord-285647-9tegcrc3 154 15 τ τ NN cord-285647-9tegcrc3 154 16 L l NN cord-285647-9tegcrc3 154 17 ) ) -RRB- cord-285647-9tegcrc3 154 18 = = NFP cord-285647-9tegcrc3 155 1 Uf Uf NNP cord-285647-9tegcrc3 155 2 ( ( -LRB- cord-285647-9tegcrc3 155 3 τ τ NN cord-285647-9tegcrc3 155 4 Λ λ NN cord-285647-9tegcrc3 155 5 ) ) -RRB- cord-285647-9tegcrc3 155 6 U U NNP cord-285647-9tegcrc3 155 7 −1 −1 NNP cord-285647-9tegcrc3 155 8 . . . cord-285647-9tegcrc3 156 1 Let let VB cord-285647-9tegcrc3 156 2 ϕ ϕ NN cord-285647-9tegcrc3 156 3 u u NN cord-285647-9tegcrc3 156 4 = = NN cord-285647-9tegcrc3 156 5 ψ ψ NN cord-285647-9tegcrc3 156 6 1,u 1,u CD cord-285647-9tegcrc3 156 7 , , , cord-285647-9tegcrc3 156 8 ψ ψ LS cord-285647-9tegcrc3 156 9 2,u 2,u CD cord-285647-9tegcrc3 156 10 , , , cord-285647-9tegcrc3 156 11 . . . cord-285647-9tegcrc3 156 12 . . . cord-285647-9tegcrc3 156 13 . . . cord-285647-9tegcrc3 157 1 , , , cord-285647-9tegcrc3 157 2 ψ ψ NNP cord-285647-9tegcrc3 157 3 n n NNP cord-285647-9tegcrc3 157 4 , , , cord-285647-9tegcrc3 157 5 u u NNP cord-285647-9tegcrc3 157 6 T T NNP cord-285647-9tegcrc3 157 7 . . . cord-285647-9tegcrc3 158 1 Then then RB cord-285647-9tegcrc3 158 2 , , , cord-285647-9tegcrc3 158 3 Therefore therefore RB cord-285647-9tegcrc3 158 4 , , , cord-285647-9tegcrc3 158 5 because because IN cord-285647-9tegcrc3 158 6 f f NNP cord-285647-9tegcrc3 158 7 ( ( -LRB- cord-285647-9tegcrc3 158 8 τ τ NN cord-285647-9tegcrc3 158 9 L L NNP cord-285647-9tegcrc3 158 10 ) ) -RRB- cord-285647-9tegcrc3 158 11 is be VBZ cord-285647-9tegcrc3 158 12 positively positively RB cord-285647-9tegcrc3 158 13 defined define VBN cord-285647-9tegcrc3 158 14 , , , cord-285647-9tegcrc3 158 15 we -PRON- PRP cord-285647-9tegcrc3 158 16 can can MD cord-285647-9tegcrc3 158 17 write write VB cord-285647-9tegcrc3 158 18 where where WRB cord-285647-9tegcrc3 158 19 Consequently consequently RB cord-285647-9tegcrc3 158 20 , , , cord-285647-9tegcrc3 158 21 D D NNP cord-285647-9tegcrc3 158 22 vw vw NNP cord-285647-9tegcrc3 158 23 is be VBZ cord-285647-9tegcrc3 158 24 a a DT cord-285647-9tegcrc3 158 25 square square JJ cord-285647-9tegcrc3 158 26 Euclidean euclidean JJ cord-285647-9tegcrc3 158 27 distance distance NN cord-285647-9tegcrc3 158 28 between between IN cord-285647-9tegcrc3 158 29 v v NN cord-285647-9tegcrc3 158 30 and and CC cord-285647-9tegcrc3 158 31 w. w. NNP cord-285647-9tegcrc3 159 1 In in IN cord-285647-9tegcrc3 159 2 this this DT cord-285647-9tegcrc3 159 3 sense sense NN cord-285647-9tegcrc3 159 4 , , , cord-285647-9tegcrc3 159 5 the the DT cord-285647-9tegcrc3 159 6 vector vector NN cord-285647-9tegcrc3 159 7 we -PRON- PRP cord-285647-9tegcrc3 159 8 have have VBP cord-285647-9tegcrc3 159 9 that that DT cord-285647-9tegcrc3 159 10 D D NNP cord-285647-9tegcrc3 159 11 vw vw NNP cord-285647-9tegcrc3 159 12 generalizes generalize VBZ cord-285647-9tegcrc3 159 13 the the DT cord-285647-9tegcrc3 159 14 diffusion diffusion NN cord-285647-9tegcrc3 159 15 distance distance NN cord-285647-9tegcrc3 159 16 studied study VBN cord-285647-9tegcrc3 159 17 by by IN cord-285647-9tegcrc3 159 18 Coifman Coifman NNP cord-285647-9tegcrc3 159 19 and and CC cord-285647-9tegcrc3 159 20 Lafon Lafon NNP cord-285647-9tegcrc3 159 21 , , , cord-285647-9tegcrc3 159 22 which which WDT cord-285647-9tegcrc3 159 23 is be VBZ cord-285647-9tegcrc3 159 24 the the DT cord-285647-9tegcrc3 159 25 particular particular JJ cord-285647-9tegcrc3 159 26 case case NN cord-285647-9tegcrc3 159 27 when when WRB cord-285647-9tegcrc3 159 28 α α NN cord-285647-9tegcrc3 159 29 = = SYM cord-285647-9tegcrc3 159 30 1 1 CD cord-285647-9tegcrc3 159 31 . . . cord-285647-9tegcrc3 160 1 Let let VB cord-285647-9tegcrc3 160 2 µ µ NN cord-285647-9tegcrc3 160 3 j j NNP cord-285647-9tegcrc3 160 4 be be VB cord-285647-9tegcrc3 160 5 the the DT cord-285647-9tegcrc3 160 6 jth jth NN cord-285647-9tegcrc3 160 7 eigenvalue eigenvalue NN cord-285647-9tegcrc3 160 8 and and CC cord-285647-9tegcrc3 161 1 ψ ψ LS cord-285647-9tegcrc3 161 2 ju ju NNP cord-285647-9tegcrc3 162 1 the the DT cord-285647-9tegcrc3 162 2 uth uth NNP cord-285647-9tegcrc3 162 3 entry entry NN cord-285647-9tegcrc3 162 4 of of IN cord-285647-9tegcrc3 162 5 the the DT cord-285647-9tegcrc3 162 6 jth jth NN cord-285647-9tegcrc3 162 7 eigenvector eigenvector NN cord-285647-9tegcrc3 162 8 of of IN cord-285647-9tegcrc3 162 9 the the DT cord-285647-9tegcrc3 162 10 Laplacian Laplacian NNP cord-285647-9tegcrc3 162 11 matrix matrix NN cord-285647-9tegcrc3 162 12 . . . cord-285647-9tegcrc3 163 1 Then then RB cord-285647-9tegcrc3 163 2 , , , cord-285647-9tegcrc3 163 3 we -PRON- PRP cord-285647-9tegcrc3 163 4 can can MD cord-285647-9tegcrc3 163 5 write write VB cord-285647-9tegcrc3 163 6 the the DT cord-285647-9tegcrc3 163 7 time time NN cord-285647-9tegcrc3 163 8 - - HYPH cord-285647-9tegcrc3 163 9 fractional fractional JJ cord-285647-9tegcrc3 163 10 diffusion diffusion NN cord-285647-9tegcrc3 163 11 distance distance NN cord-285647-9tegcrc3 163 12 as as IN cord-285647-9tegcrc3 163 13 It -PRON- PRP cord-285647-9tegcrc3 163 14 is be VBZ cord-285647-9tegcrc3 163 15 evident evident JJ cord-285647-9tegcrc3 163 16 that that IN cord-285647-9tegcrc3 163 17 when when WRB cord-285647-9tegcrc3 163 18 α α NN cord-285647-9tegcrc3 163 19 = = SYM cord-285647-9tegcrc3 163 20 1 1 CD cord-285647-9tegcrc3 163 21 , , , cord-285647-9tegcrc3 163 22 D D NNP cord-285647-9tegcrc3 163 23 vw vw NNP cord-285647-9tegcrc3 163 24 is be VBZ cord-285647-9tegcrc3 163 25 exactly exactly RB cord-285647-9tegcrc3 163 26 the the DT cord-285647-9tegcrc3 163 27 diffusion diffusion NN cord-285647-9tegcrc3 163 28 distance distance NN cord-285647-9tegcrc3 163 29 previously previously RB cord-285647-9tegcrc3 163 30 studied study VBN cord-285647-9tegcrc3 163 31 by by IN cord-285647-9tegcrc3 163 32 Coifman Coifman NNP cord-285647-9tegcrc3 163 33 and and CC cord-285647-9tegcrc3 163 34 Lafon Lafon NNP cord-285647-9tegcrc3 163 35 . . . cord-285647-9tegcrc3 164 1 47 47 CD cord-285647-9tegcrc3 165 1 The the DT cord-285647-9tegcrc3 165 2 fractionaltime fractionaltime NN cord-285647-9tegcrc3 165 3 diffusion diffusion NN cord-285647-9tegcrc3 165 4 distance distance NN cord-285647-9tegcrc3 165 5 between between IN cord-285647-9tegcrc3 165 6 every every DT cord-285647-9tegcrc3 165 7 pair pair NN cord-285647-9tegcrc3 165 8 of of IN cord-285647-9tegcrc3 165 9 nodes node NNS cord-285647-9tegcrc3 165 10 in in IN cord-285647-9tegcrc3 165 11 a a DT cord-285647-9tegcrc3 165 12 network network NN cord-285647-9tegcrc3 165 13 can can MD cord-285647-9tegcrc3 165 14 be be VB cord-285647-9tegcrc3 165 15 represented represent VBN cord-285647-9tegcrc3 165 16 in in IN cord-285647-9tegcrc3 165 17 a a DT cord-285647-9tegcrc3 165 18 matrix matrix NN cord-285647-9tegcrc3 165 19 form form NN cord-285647-9tegcrc3 165 20 as as IN cord-285647-9tegcrc3 165 21 follows follow VBZ cord-285647-9tegcrc3 165 22 : : : cord-285647-9tegcrc3 165 23 where where WRB cord-285647-9tegcrc3 165 24 s s NN cord-285647-9tegcrc3 165 25 = = SYM cord-285647-9tegcrc3 165 26 f(τ f(τ NNP cord-285647-9tegcrc3 165 27 L L NNP cord-285647-9tegcrc3 165 28 ) ) -RRB- cord-285647-9tegcrc3 165 29 11 11 CD cord-285647-9tegcrc3 165 30 , , , cord-285647-9tegcrc3 165 31 f(τ f(τ NNP cord-285647-9tegcrc3 165 32 L L NNP cord-285647-9tegcrc3 165 33 ) ) -RRB- cord-285647-9tegcrc3 165 34 22 22 CD cord-285647-9tegcrc3 165 35 , , , cord-285647-9tegcrc3 165 36 . . . cord-285647-9tegcrc3 165 37 . . . cord-285647-9tegcrc3 165 38 . . . cord-285647-9tegcrc3 166 1 , , , cord-285647-9tegcrc3 166 2 f(τ f(τ NNP cord-285647-9tegcrc3 166 3 L L NNP cord-285647-9tegcrc3 166 4 ) ) -RRB- cord-285647-9tegcrc3 166 5 nn nn NNP cord-285647-9tegcrc3 166 6 is be VBZ cord-285647-9tegcrc3 166 7 a a DT cord-285647-9tegcrc3 166 8 vector vector NN cord-285647-9tegcrc3 166 9 whose whose WP$ cord-285647-9tegcrc3 166 10 entries entry NNS cord-285647-9tegcrc3 166 11 are be VBP cord-285647-9tegcrc3 166 12 the the DT cord-285647-9tegcrc3 166 13 main main JJ cord-285647-9tegcrc3 166 14 diagonal diagonal JJ cord-285647-9tegcrc3 166 15 terms term NNS cord-285647-9tegcrc3 166 16 of of IN cord-285647-9tegcrc3 166 17 the the DT cord-285647-9tegcrc3 166 18 Mittag Mittag NNP cord-285647-9tegcrc3 166 19 - - HYPH cord-285647-9tegcrc3 166 20 Leffler Leffler NNP cord-285647-9tegcrc3 166 21 matrix matrix NN cord-285647-9tegcrc3 166 22 function function NN cord-285647-9tegcrc3 166 23 , , , cord-285647-9tegcrc3 166 24 1 1 CD cord-285647-9tegcrc3 166 25 is be VBZ cord-285647-9tegcrc3 166 26 an an DT cord-285647-9tegcrc3 166 27 all all RB cord-285647-9tegcrc3 166 28 - - HYPH cord-285647-9tegcrc3 166 29 ones one NNS cord-285647-9tegcrc3 166 30 vector vector NN cord-285647-9tegcrc3 166 31 , , , cord-285647-9tegcrc3 166 32 and and CC cord-285647-9tegcrc3 166 33 • • NNP cord-285647-9tegcrc3 166 34 indicates indicate VBZ cord-285647-9tegcrc3 166 35 an an DT cord-285647-9tegcrc3 166 36 entrywise entrywise JJ cord-285647-9tegcrc3 166 37 operation operation NN cord-285647-9tegcrc3 166 38 . . . cord-285647-9tegcrc3 167 1 Using use VBG cord-285647-9tegcrc3 167 2 this this DT cord-285647-9tegcrc3 167 3 matrix matrix NN cord-285647-9tegcrc3 167 4 , , , cord-285647-9tegcrc3 167 5 we -PRON- PRP cord-285647-9tegcrc3 167 6 can can MD cord-285647-9tegcrc3 167 7 build build VB cord-285647-9tegcrc3 167 8 the the DT cord-285647-9tegcrc3 167 9 diffusion diffusion NN cord-285647-9tegcrc3 167 10 distance distance NN cord-285647-9tegcrc3 167 11 - - HYPH cord-285647-9tegcrc3 167 12 weighted weight VBN cord-285647-9tegcrc3 167 13 adjacency adjacency NN cord-285647-9tegcrc3 167 14 matrix matrix NN cord-285647-9tegcrc3 167 15 of of IN cord-285647-9tegcrc3 167 16 the the DT cord-285647-9tegcrc3 167 17 network network NN cord-285647-9tegcrc3 167 18 , , , cord-285647-9tegcrc3 167 19 The the DT cord-285647-9tegcrc3 167 20 shortest short JJS cord-285647-9tegcrc3 167 21 diffusion diffusion NN cord-285647-9tegcrc3 167 22 path path NN cord-285647-9tegcrc3 167 23 between between IN cord-285647-9tegcrc3 167 24 two two CD cord-285647-9tegcrc3 167 25 nodes node NNS cord-285647-9tegcrc3 167 26 is be VBZ cord-285647-9tegcrc3 167 27 then then RB cord-285647-9tegcrc3 167 28 the the DT cord-285647-9tegcrc3 167 29 shortest short JJS cord-285647-9tegcrc3 167 30 weighted weighted JJ cord-285647-9tegcrc3 167 31 path path NN cord-285647-9tegcrc3 167 32 in in IN cord-285647-9tegcrc3 167 33 W w NN cord-285647-9tegcrc3 167 34 ( ( -LRB- cord-285647-9tegcrc3 167 35 τ τ NN cord-285647-9tegcrc3 167 36 ) ) -RRB- cord-285647-9tegcrc3 167 37 . . . cord-285647-9tegcrc3 168 1 Lemma Lemma NNP cord-285647-9tegcrc3 168 2 3 3 CD cord-285647-9tegcrc3 168 3 . . . cord-285647-9tegcrc3 169 1 The the DT cord-285647-9tegcrc3 169 2 shortest short JJS cord-285647-9tegcrc3 169 3 ( ( -LRB- cord-285647-9tegcrc3 169 4 topological topological JJ cord-285647-9tegcrc3 169 5 ) ) -RRB- cord-285647-9tegcrc3 169 6 path path NN cord-285647-9tegcrc3 169 7 distance distance NN cord-285647-9tegcrc3 169 8 between between IN cord-285647-9tegcrc3 169 9 two two CD cord-285647-9tegcrc3 169 10 nodes node NNS cord-285647-9tegcrc3 169 11 in in IN cord-285647-9tegcrc3 169 12 a a DT cord-285647-9tegcrc3 169 13 graph graph NN cord-285647-9tegcrc3 169 14 is be VBZ cord-285647-9tegcrc3 169 15 a a DT cord-285647-9tegcrc3 169 16 particular particular JJ cord-285647-9tegcrc3 169 17 case case NN cord-285647-9tegcrc3 169 18 of of IN cord-285647-9tegcrc3 169 19 the the DT cord-285647-9tegcrc3 169 20 time time NN cord-285647-9tegcrc3 169 21 - - HYPH cord-285647-9tegcrc3 169 22 fractional fractional JJ cord-285647-9tegcrc3 169 23 shortest short JJS cord-285647-9tegcrc3 169 24 diffusion diffusion NN cord-285647-9tegcrc3 169 25 path path NN cord-285647-9tegcrc3 169 26 length length NN cord-285647-9tegcrc3 169 27 for for IN cord-285647-9tegcrc3 169 28 τ τ NN cord-285647-9tegcrc3 169 29 → → IN cord-285647-9tegcrc3 169 30 0 0 CD cord-285647-9tegcrc3 169 31 . . . cord-285647-9tegcrc3 170 1 Proof proof NN cord-285647-9tegcrc3 170 2 . . . cord-285647-9tegcrc3 171 1 Let let VB cord-285647-9tegcrc3 171 2 us -PRON- PRP cord-285647-9tegcrc3 171 3 consider consider VB cord-285647-9tegcrc3 171 4 each each DT cord-285647-9tegcrc3 171 5 of of IN cord-285647-9tegcrc3 171 6 the the DT cord-285647-9tegcrc3 171 7 terms term NNS cord-285647-9tegcrc3 171 8 forming form VBG cord-285647-9tegcrc3 171 9 the the DT cord-285647-9tegcrc3 171 10 definition definition NN cord-285647-9tegcrc3 171 11 of of IN cord-285647-9tegcrc3 171 12 the the DT cord-285647-9tegcrc3 171 13 time time NN cord-285647-9tegcrc3 171 14 - - HYPH cord-285647-9tegcrc3 171 15 fractional fractional JJ cord-285647-9tegcrc3 171 16 diffusion diffusion NN cord-285647-9tegcrc3 171 17 distance distance NN cord-285647-9tegcrc3 171 18 and and CC cord-285647-9tegcrc3 171 19 apply apply VB cord-285647-9tegcrc3 171 20 the the DT cord-285647-9tegcrc3 171 21 limit limit NN cord-285647-9tegcrc3 171 22 of of IN cord-285647-9tegcrc3 171 23 the the DT cord-285647-9tegcrc3 171 24 very very RB cord-285647-9tegcrc3 171 25 small small JJ cord-285647-9tegcrc3 171 26 −t −t NNP cord-285647-9tegcrc3 171 27 α α NN cord-285647-9tegcrc3 171 28 . . . cord-285647-9tegcrc3 172 1 That that RB cord-285647-9tegcrc3 172 2 is is RB cord-285647-9tegcrc3 172 3 , , , cord-285647-9tegcrc3 172 4 Chaos Chaos NNP cord-285647-9tegcrc3 172 5 ARTICLE article NN cord-285647-9tegcrc3 172 6 scitation.org/journal/cha scitation.org/journal/cha , cord-285647-9tegcrc3 172 7 and and CC cord-285647-9tegcrc3 172 8 in in IN cord-285647-9tegcrc3 172 9 a a DT cord-285647-9tegcrc3 172 10 similar similar JJ cord-285647-9tegcrc3 172 11 way way NN cord-285647-9tegcrc3 172 12 , , , cord-285647-9tegcrc3 173 1 Therefore therefore RB cord-285647-9tegcrc3 173 2 , , , cord-285647-9tegcrc3 173 3 lim lim NNP cord-285647-9tegcrc3 173 4 , , , cord-285647-9tegcrc3 173 5 which which WDT cord-285647-9tegcrc3 173 6 immediately immediately RB cord-285647-9tegcrc3 173 7 implies imply VBZ cord-285647-9tegcrc3 173 8 that that IN cord-285647-9tegcrc3 173 9 the the DT cord-285647-9tegcrc3 173 10 time time NN cord-285647-9tegcrc3 173 11 - - HYPH cord-285647-9tegcrc3 173 12 fractional fractional JJ cord-285647-9tegcrc3 173 13 shortest short JJS cord-285647-9tegcrc3 173 14 diffusion diffusion NN cord-285647-9tegcrc3 173 15 path path NN cord-285647-9tegcrc3 173 16 is be VBZ cord-285647-9tegcrc3 173 17 identical identical JJ cord-285647-9tegcrc3 173 18 to to IN cord-285647-9tegcrc3 173 19 the the DT cord-285647-9tegcrc3 173 20 shortest short JJS cord-285647-9tegcrc3 173 21 ( ( -LRB- cord-285647-9tegcrc3 173 22 topological topological JJ cord-285647-9tegcrc3 173 23 ) ) -RRB- cord-285647-9tegcrc3 173 24 one one CD cord-285647-9tegcrc3 173 25 in in IN cord-285647-9tegcrc3 173 26 the the DT cord-285647-9tegcrc3 173 27 limit limit NN cord-285647-9tegcrc3 173 28 of of IN cord-285647-9tegcrc3 173 29 very very RB cord-285647-9tegcrc3 173 30 small small JJ cord-285647-9tegcrc3 173 31 τ τ NN cord-285647-9tegcrc3 173 32 = = NFP cord-285647-9tegcrc3 173 33 −t −t NNP cord-285647-9tegcrc3 173 34 α α NN cord-285647-9tegcrc3 173 35 . . . cord-285647-9tegcrc3 174 1 The the DT cord-285647-9tegcrc3 174 2 proteins protein NNS cord-285647-9tegcrc3 174 3 of of IN cord-285647-9tegcrc3 174 4 SARS SARS NNP cord-285647-9tegcrc3 174 5 - - HYPH cord-285647-9tegcrc3 174 6 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 174 7 and and CC cord-285647-9tegcrc3 174 8 their -PRON- PRP$ cord-285647-9tegcrc3 174 9 interactions interaction NNS cord-285647-9tegcrc3 174 10 with with IN cord-285647-9tegcrc3 174 11 human human JJ cord-285647-9tegcrc3 174 12 proteins protein NNS cord-285647-9tegcrc3 174 13 were be VBD cord-285647-9tegcrc3 174 14 determined determine VBN cord-285647-9tegcrc3 174 15 experimentally experimentally RB cord-285647-9tegcrc3 174 16 by by IN cord-285647-9tegcrc3 174 17 Gordon Gordon NNP cord-285647-9tegcrc3 174 18 et et NNP cord-285647-9tegcrc3 174 19 al al NNP cord-285647-9tegcrc3 174 20 . . . cord-285647-9tegcrc3 175 1 14 14 CD cord-285647-9tegcrc3 176 1 Gysi Gysi NNP cord-285647-9tegcrc3 176 2 et et FW cord-285647-9tegcrc3 176 3 al al NNP cord-285647-9tegcrc3 176 4 . . . cord-285647-9tegcrc3 177 1 15 15 CD cord-285647-9tegcrc3 177 2 constructed construct VBD cord-285647-9tegcrc3 177 3 an an DT cord-285647-9tegcrc3 177 4 interaction interaction NN cord-285647-9tegcrc3 177 5 network network NN cord-285647-9tegcrc3 177 6 of of IN cord-285647-9tegcrc3 177 7 all all DT cord-285647-9tegcrc3 177 8 239 239 CD cord-285647-9tegcrc3 177 9 human human JJ cord-285647-9tegcrc3 177 10 proteins protein NNS cord-285647-9tegcrc3 177 11 targeted target VBN cord-285647-9tegcrc3 177 12 by by IN cord-285647-9tegcrc3 177 13 SARS SARS NNP cord-285647-9tegcrc3 177 14 - - HYPH cord-285647-9tegcrc3 177 15 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 177 16 . . . cord-285647-9tegcrc3 178 1 In in IN cord-285647-9tegcrc3 178 2 this this DT cord-285647-9tegcrc3 178 3 network network NN cord-285647-9tegcrc3 178 4 , , , cord-285647-9tegcrc3 178 5 the the DT cord-285647-9tegcrc3 178 6 nodes node NNS cord-285647-9tegcrc3 178 7 represent represent VBP cord-285647-9tegcrc3 178 8 human human JJ cord-285647-9tegcrc3 178 9 proteins protein NNS cord-285647-9tegcrc3 178 10 targeted target VBN cord-285647-9tegcrc3 178 11 by by IN cord-285647-9tegcrc3 178 12 SARS SARS NNP cord-285647-9tegcrc3 178 13 - - HYPH cord-285647-9tegcrc3 178 14 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 178 15 and and CC cord-285647-9tegcrc3 178 16 two two CD cord-285647-9tegcrc3 178 17 nodes node NNS cord-285647-9tegcrc3 178 18 are be VBP cord-285647-9tegcrc3 178 19 connected connect VBN cord-285647-9tegcrc3 178 20 if if IN cord-285647-9tegcrc3 178 21 the the DT cord-285647-9tegcrc3 178 22 corresponding correspond VBG cord-285647-9tegcrc3 178 23 proteins protein NNS cord-285647-9tegcrc3 178 24 have have VBP cord-285647-9tegcrc3 178 25 been be VBN cord-285647-9tegcrc3 178 26 determined determine VBN cord-285647-9tegcrc3 178 27 to to TO cord-285647-9tegcrc3 178 28 interact interact VB cord-285647-9tegcrc3 178 29 with with IN cord-285647-9tegcrc3 178 30 each each DT cord-285647-9tegcrc3 178 31 other other JJ cord-285647-9tegcrc3 178 32 . . . cord-285647-9tegcrc3 179 1 Obviously obviously RB cord-285647-9tegcrc3 179 2 , , , cord-285647-9tegcrc3 179 3 this this DT cord-285647-9tegcrc3 179 4 network network NN cord-285647-9tegcrc3 179 5 of of IN cord-285647-9tegcrc3 179 6 proteins protein NNS cord-285647-9tegcrc3 179 7 targeted target VBN cord-285647-9tegcrc3 179 8 by by IN cord-285647-9tegcrc3 179 9 SARS SARS NNP cord-285647-9tegcrc3 179 10 - - HYPH cord-285647-9tegcrc3 179 11 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 179 12 is be VBZ cord-285647-9tegcrc3 179 13 a a DT cord-285647-9tegcrc3 179 14 subgraph subgraph NN cord-285647-9tegcrc3 179 15 of of IN cord-285647-9tegcrc3 179 16 the the DT cord-285647-9tegcrc3 179 17 protein protein NN cord-285647-9tegcrc3 179 18 - - HYPH cord-285647-9tegcrc3 179 19 protein protein NN cord-285647-9tegcrc3 179 20 interaction interaction NN cord-285647-9tegcrc3 179 21 ( ( -LRB- cord-285647-9tegcrc3 179 22 PPI PPI NNP cord-285647-9tegcrc3 179 23 ) ) -RRB- cord-285647-9tegcrc3 179 24 network network NN cord-285647-9tegcrc3 179 25 of of IN cord-285647-9tegcrc3 179 26 humans human NNS cord-285647-9tegcrc3 179 27 . . . cord-285647-9tegcrc3 180 1 One one CD cord-285647-9tegcrc3 180 2 of of IN cord-285647-9tegcrc3 180 3 the the DT cord-285647-9tegcrc3 180 4 surprising surprising JJ cord-285647-9tegcrc3 180 5 findings finding NNS cord-285647-9tegcrc3 180 6 of of IN cord-285647-9tegcrc3 180 7 Gysi Gysi NNP cord-285647-9tegcrc3 180 8 et et NNP cord-285647-9tegcrc3 180 9 al al NNP cord-285647-9tegcrc3 180 10 . . . cord-285647-9tegcrc3 181 1 15 15 CD cord-285647-9tegcrc3 181 2 is be VBZ cord-285647-9tegcrc3 181 3 the the DT cord-285647-9tegcrc3 181 4 fact fact NN cord-285647-9tegcrc3 181 5 that that IN cord-285647-9tegcrc3 181 6 this this DT cord-285647-9tegcrc3 181 7 subgraph subgraph NN cord-285647-9tegcrc3 181 8 is be VBZ cord-285647-9tegcrc3 181 9 not not RB cord-285647-9tegcrc3 181 10 formed form VBN cord-285647-9tegcrc3 181 11 by by IN cord-285647-9tegcrc3 181 12 proteins protein NNS cord-285647-9tegcrc3 181 13 randomly randomly RB cord-285647-9tegcrc3 181 14 distributed distribute VBN cord-285647-9tegcrc3 181 15 across across IN cord-285647-9tegcrc3 181 16 the the DT cord-285647-9tegcrc3 181 17 human human JJ cord-285647-9tegcrc3 181 18 PPI PPI NNP cord-285647-9tegcrc3 181 19 , , , cord-285647-9tegcrc3 181 20 but but CC cord-285647-9tegcrc3 181 21 they -PRON- PRP cord-285647-9tegcrc3 181 22 form form VBP cord-285647-9tegcrc3 181 23 a a DT cord-285647-9tegcrc3 181 24 main main JJ cord-285647-9tegcrc3 181 25 cluster cluster NN cord-285647-9tegcrc3 181 26 of of IN cord-285647-9tegcrc3 181 27 208 208 CD cord-285647-9tegcrc3 181 28 proteins protein NNS cord-285647-9tegcrc3 181 29 and and CC cord-285647-9tegcrc3 181 30 a a DT cord-285647-9tegcrc3 181 31 few few JJ cord-285647-9tegcrc3 181 32 small small JJ cord-285647-9tegcrc3 181 33 isolated isolate VBN cord-285647-9tegcrc3 181 34 components component NNS cord-285647-9tegcrc3 181 35 . . . cord-285647-9tegcrc3 182 1 Hereafter hereafter RB cord-285647-9tegcrc3 182 2 , , , cord-285647-9tegcrc3 182 3 we -PRON- PRP cord-285647-9tegcrc3 182 4 will will MD cord-285647-9tegcrc3 182 5 always always RB cord-285647-9tegcrc3 182 6 consider consider VB cord-285647-9tegcrc3 182 7 this this DT cord-285647-9tegcrc3 182 8 connected connected JJ cord-285647-9tegcrc3 182 9 component component NN cord-285647-9tegcrc3 182 10 of of IN cord-285647-9tegcrc3 182 11 human human JJ cord-285647-9tegcrc3 182 12 proteins protein NNS cord-285647-9tegcrc3 182 13 targeted target VBN cord-285647-9tegcrc3 182 14 by by IN cord-285647-9tegcrc3 182 15 SARS SARS NNP cord-285647-9tegcrc3 182 16 - - HYPH cord-285647-9tegcrc3 182 17 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 182 18 . . . cord-285647-9tegcrc3 183 1 This this DT cord-285647-9tegcrc3 183 2 network network NN cord-285647-9tegcrc3 183 3 is be VBZ cord-285647-9tegcrc3 183 4 formed form VBN cord-285647-9tegcrc3 183 5 by by IN cord-285647-9tegcrc3 183 6 193 193 CD cord-285647-9tegcrc3 183 7 proteins protein NNS cord-285647-9tegcrc3 183 8 , , , cord-285647-9tegcrc3 183 9 which which WDT cord-285647-9tegcrc3 183 10 are be VBP cord-285647-9tegcrc3 183 11 significantly significantly RB cord-285647-9tegcrc3 183 12 expressed express VBN cord-285647-9tegcrc3 183 13 in in IN cord-285647-9tegcrc3 183 14 the the DT cord-285647-9tegcrc3 183 15 lungs lung NNS cord-285647-9tegcrc3 183 16 . . . cord-285647-9tegcrc3 184 1 Gysi Gysi NNP cord-285647-9tegcrc3 184 2 et et FW cord-285647-9tegcrc3 184 3 al al NNP cord-285647-9tegcrc3 184 4 . . . cord-285647-9tegcrc3 185 1 15 15 CD cord-285647-9tegcrc3 185 2 reported report VBD cord-285647-9tegcrc3 185 3 a a DT cord-285647-9tegcrc3 185 4 protein protein NN cord-285647-9tegcrc3 185 5 as as IN cord-285647-9tegcrc3 185 6 being be VBG cord-285647-9tegcrc3 185 7 significantly significantly RB cord-285647-9tegcrc3 185 8 expressed express VBN cord-285647-9tegcrc3 185 9 in in IN cord-285647-9tegcrc3 185 10 the the DT cord-285647-9tegcrc3 185 11 lungs lung NNS cord-285647-9tegcrc3 185 12 if if IN cord-285647-9tegcrc3 185 13 its -PRON- PRP$ cord-285647-9tegcrc3 185 14 GTEx gtex NN cord-285647-9tegcrc3 185 15 median median JJ cord-285647-9tegcrc3 185 16 value value NN cord-285647-9tegcrc3 185 17 is be VBZ cord-285647-9tegcrc3 185 18 larger large JJR cord-285647-9tegcrc3 185 19 than than IN cord-285647-9tegcrc3 185 20 5 5 CD cord-285647-9tegcrc3 185 21 . . . cord-285647-9tegcrc3 186 1 GTEx GTEx NNP cord-285647-9tegcrc3 186 2 48 48 CD cord-285647-9tegcrc3 186 3 is be VBZ cord-285647-9tegcrc3 186 4 a a DT cord-285647-9tegcrc3 186 5 database database NN cord-285647-9tegcrc3 186 6 containing contain VBG cord-285647-9tegcrc3 186 7 the the DT cord-285647-9tegcrc3 186 8 median median JJ cord-285647-9tegcrc3 186 9 gene gene NN cord-285647-9tegcrc3 186 10 expression expression NN cord-285647-9tegcrc3 186 11 from from IN cord-285647-9tegcrc3 186 12 RNA RNA NNP cord-285647-9tegcrc3 186 13 - - HYPH cord-285647-9tegcrc3 186 14 seq seq NN cord-285647-9tegcrc3 186 15 in in IN cord-285647-9tegcrc3 186 16 different different JJ cord-285647-9tegcrc3 186 17 tissues tissue NNS cord-285647-9tegcrc3 186 18 . . . cord-285647-9tegcrc3 187 1 The the DT cord-285647-9tegcrc3 187 2 other other JJ cord-285647-9tegcrc3 187 3 15 15 CD cord-285647-9tegcrc3 187 4 proteins protein NNS cord-285647-9tegcrc3 187 5 are be VBP cord-285647-9tegcrc3 187 6 mainly mainly RB cord-285647-9tegcrc3 187 7 expressed express VBN cord-285647-9tegcrc3 187 8 in in IN cord-285647-9tegcrc3 187 9 other other JJ cord-285647-9tegcrc3 187 10 tissues tissue NNS cord-285647-9tegcrc3 187 11 . . . cord-285647-9tegcrc3 188 1 However however RB cord-285647-9tegcrc3 188 2 , , , cord-285647-9tegcrc3 188 3 in in IN cord-285647-9tegcrc3 188 4 reporting report VBG cord-285647-9tegcrc3 188 5 here here RB cord-285647-9tegcrc3 188 6 , , , cord-285647-9tegcrc3 188 7 the the DT cord-285647-9tegcrc3 188 8 tissues tissue NNS cord-285647-9tegcrc3 188 9 that that WDT cord-285647-9tegcrc3 188 10 were be VBD cord-285647-9tegcrc3 188 11 proteins protein NNS cord-285647-9tegcrc3 188 12 are be VBP cord-285647-9tegcrc3 188 13 mainly mainly RB cord-285647-9tegcrc3 188 14 expressed express VBN cord-285647-9tegcrc3 188 15 ; ; : cord-285647-9tegcrc3 188 16 we -PRON- PRP cord-285647-9tegcrc3 188 17 use use VBP cord-285647-9tegcrc3 188 18 the the DT cord-285647-9tegcrc3 188 19 information information NN cord-285647-9tegcrc3 188 20 reported report VBN cord-285647-9tegcrc3 188 21 in in IN cord-285647-9tegcrc3 188 22 The the DT cord-285647-9tegcrc3 188 23 Human Human NNP cord-285647-9tegcrc3 188 24 Protein Protein NNP cord-285647-9tegcrc3 188 25 Atlas Atlas NNP cord-285647-9tegcrc3 188 26 49 49 CD cord-285647-9tegcrc3 188 27 where where WRB cord-285647-9tegcrc3 188 28 we -PRON- PRP cord-285647-9tegcrc3 188 29 use use VBP cord-285647-9tegcrc3 188 30 information information NN cord-285647-9tegcrc3 188 31 not not RB cord-285647-9tegcrc3 188 32 only only RB cord-285647-9tegcrc3 188 33 from from IN cord-285647-9tegcrc3 188 34 GTEx gtex NN cord-285647-9tegcrc3 188 35 but but CC cord-285647-9tegcrc3 188 36 also also RB cord-285647-9tegcrc3 188 37 from from IN cord-285647-9tegcrc3 188 38 HPA HPA NNP cord-285647-9tegcrc3 188 39 ( ( -LRB- cord-285647-9tegcrc3 188 40 see see VB cord-285647-9tegcrc3 188 41 details detail NNS cord-285647-9tegcrc3 188 42 at at IN cord-285647-9tegcrc3 188 43 the the DT cord-285647-9tegcrc3 188 44 Human Human NNP cord-285647-9tegcrc3 188 45 Protein Protein NNP cord-285647-9tegcrc3 188 46 Atlas Atlas NNP cord-285647-9tegcrc3 188 47 webpage webpage NN cord-285647-9tegcrc3 188 48 ) ) -RRB- cord-285647-9tegcrc3 188 49 and and CC cord-285647-9tegcrc3 188 50 FANTOM5 fantom5 NN cord-285647-9tegcrc3 188 51 50 50 CD cord-285647-9tegcrc3 188 52 datasets dataset NNS cord-285647-9tegcrc3 188 53 . . . cord-285647-9tegcrc3 189 1 The the DT cord-285647-9tegcrc3 189 2 PPI PPI NNP cord-285647-9tegcrc3 189 3 network network NN cord-285647-9tegcrc3 189 4 of of IN cord-285647-9tegcrc3 189 5 human human JJ cord-285647-9tegcrc3 189 6 proteins protein NNS cord-285647-9tegcrc3 189 7 targeted target VBN cord-285647-9tegcrc3 189 8 by by IN cord-285647-9tegcrc3 189 9 SARS SARS NNP cord-285647-9tegcrc3 189 10 - - HYPH cord-285647-9tegcrc3 189 11 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 189 12 is be VBZ cord-285647-9tegcrc3 189 13 very very RB cord-285647-9tegcrc3 189 14 sparse sparse JJ cord-285647-9tegcrc3 189 15 , , , cord-285647-9tegcrc3 189 16 having have VBG cord-285647-9tegcrc3 189 17 360 360 CD cord-285647-9tegcrc3 189 18 edges edge NNS cord-285647-9tegcrc3 189 19 , , , cord-285647-9tegcrc3 189 20 i.e. i.e. FW cord-285647-9tegcrc3 189 21 , , , cord-285647-9tegcrc3 189 22 its -PRON- PRP$ cord-285647-9tegcrc3 189 23 edge edge NN cord-285647-9tegcrc3 189 24 density density NN cord-285647-9tegcrc3 189 25 is be VBZ cord-285647-9tegcrc3 189 26 0.0167 0.0167 CD cord-285647-9tegcrc3 189 27 , , , cord-285647-9tegcrc3 189 28 30 30 CD cord-285647-9tegcrc3 189 29 % % NN cord-285647-9tegcrc3 189 30 of of IN cord-285647-9tegcrc3 189 31 nodes node NNS cord-285647-9tegcrc3 189 32 have have VBP cord-285647-9tegcrc3 189 33 a a DT cord-285647-9tegcrc3 189 34 degree degree NN cord-285647-9tegcrc3 190 1 ( ( -LRB- cord-285647-9tegcrc3 190 2 number number NN cord-285647-9tegcrc3 190 3 of of IN cord-285647-9tegcrc3 190 4 connections connection NNS cord-285647-9tegcrc3 190 5 per per IN cord-285647-9tegcrc3 190 6 protein protein NN cord-285647-9tegcrc3 190 7 ) ) -RRB- cord-285647-9tegcrc3 190 8 equal equal JJ cord-285647-9tegcrc3 190 9 to to IN cord-285647-9tegcrc3 190 10 one one CD cord-285647-9tegcrc3 190 11 , , , cord-285647-9tegcrc3 190 12 and and CC cord-285647-9tegcrc3 190 13 the the DT cord-285647-9tegcrc3 190 14 maximum maximum JJ cord-285647-9tegcrc3 190 15 degree degree NN cord-285647-9tegcrc3 190 16 of of IN cord-285647-9tegcrc3 190 17 a a DT cord-285647-9tegcrc3 190 18 protein protein NN cord-285647-9tegcrc3 190 19 is be VBZ cord-285647-9tegcrc3 190 20 14 14 CD cord-285647-9tegcrc3 190 21 . . . cord-285647-9tegcrc3 191 1 The the DT cord-285647-9tegcrc3 191 2 second second JJ cord-285647-9tegcrc3 191 3 smallest small JJS cord-285647-9tegcrc3 191 4 eigenvalue eigenvalue NN cord-285647-9tegcrc3 191 5 of of IN cord-285647-9tegcrc3 191 6 the the DT cord-285647-9tegcrc3 191 7 Laplacian Laplacian NNP cord-285647-9tegcrc3 191 8 matrix matrix NN cord-285647-9tegcrc3 191 9 of of IN cord-285647-9tegcrc3 191 10 this this DT cord-285647-9tegcrc3 191 11 network network NN cord-285647-9tegcrc3 191 12 is be VBZ cord-285647-9tegcrc3 191 13 very very RB cord-285647-9tegcrc3 191 14 small small JJ cord-285647-9tegcrc3 191 15 ; ; : cord-285647-9tegcrc3 191 16 i.e. i.e. FW cord-285647-9tegcrc3 191 17 , , , cord-285647-9tegcrc3 191 18 µ µ NN cord-285647-9tegcrc3 191 19 2 2 CD cord-285647-9tegcrc3 191 20 = = SYM cord-285647-9tegcrc3 191 21 0.0647 0.0647 CD cord-285647-9tegcrc3 191 22 . . . cord-285647-9tegcrc3 192 1 Therefore therefore RB cord-285647-9tegcrc3 192 2 , , , cord-285647-9tegcrc3 192 3 the the DT cord-285647-9tegcrc3 192 4 rate rate NN cord-285647-9tegcrc3 192 5 of of IN cord-285647-9tegcrc3 192 6 convergence convergence NN cord-285647-9tegcrc3 192 7 to to IN cord-285647-9tegcrc3 192 8 the the DT cord-285647-9tegcrc3 192 9 steady steady JJ cord-285647-9tegcrc3 192 10 state state NN cord-285647-9tegcrc3 192 11 of of IN cord-285647-9tegcrc3 192 12 the the DT cord-285647-9tegcrc3 192 13 diffusion diffusion NN cord-285647-9tegcrc3 192 14 processes process NNS cord-285647-9tegcrc3 192 15 taking take VBG cord-285647-9tegcrc3 192 16 place place NN cord-285647-9tegcrc3 192 17 on on IN cord-285647-9tegcrc3 192 18 this this DT cord-285647-9tegcrc3 192 19 PPI PPI NNP cord-285647-9tegcrc3 192 20 is be VBZ cord-285647-9tegcrc3 192 21 very very RB cord-285647-9tegcrc3 192 22 slow slow JJ cord-285647-9tegcrc3 192 23 . . . cord-285647-9tegcrc3 193 1 We -PRON- PRP cord-285647-9tegcrc3 193 2 start start VBP cord-285647-9tegcrc3 193 3 by by IN cord-285647-9tegcrc3 193 4 analyzing analyze VBG cord-285647-9tegcrc3 193 5 the the DT cord-285647-9tegcrc3 193 6 effects effect NNS cord-285647-9tegcrc3 193 7 of of IN cord-285647-9tegcrc3 193 8 the the DT cord-285647-9tegcrc3 193 9 fractional fractional JJ cord-285647-9tegcrc3 193 10 coefficient coefficient NN cord-285647-9tegcrc3 193 11 α α NN cord-285647-9tegcrc3 193 12 on on IN cord-285647-9tegcrc3 193 13 these these DT cord-285647-9tegcrc3 193 14 diffusive diffusive JJ cord-285647-9tegcrc3 193 15 dynamics dynamic NNS cord-285647-9tegcrc3 193 16 . . . cord-285647-9tegcrc3 194 1 We -PRON- PRP cord-285647-9tegcrc3 194 2 use use VBP cord-285647-9tegcrc3 194 3 the the DT cord-285647-9tegcrc3 194 4 normal normal JJ cord-285647-9tegcrc3 194 5 diffusion diffusion NN cord-285647-9tegcrc3 194 6 α α NN cord-285647-9tegcrc3 194 7 = = SYM cord-285647-9tegcrc3 194 8 1 1 CD cord-285647-9tegcrc3 194 9 as as IN cord-285647-9tegcrc3 194 10 the the DT cord-285647-9tegcrc3 194 11 reference reference NN cord-285647-9tegcrc3 194 12 system system NN cord-285647-9tegcrc3 194 13 . . . cord-285647-9tegcrc3 195 1 To to TO cord-285647-9tegcrc3 195 2 analyze analyze VB cord-285647-9tegcrc3 195 3 the the DT cord-285647-9tegcrc3 195 4 effects effect NNS cord-285647-9tegcrc3 195 5 of of IN cord-285647-9tegcrc3 195 6 changing change VBG cord-285647-9tegcrc3 195 7 α α NN cord-285647-9tegcrc3 195 8 over over IN cord-285647-9tegcrc3 195 9 the the DT cord-285647-9tegcrc3 195 10 diffusive diffusive JJ cord-285647-9tegcrc3 195 11 dynamics dynamic NNS cord-285647-9tegcrc3 195 12 on on IN cord-285647-9tegcrc3 195 13 the the DT cord-285647-9tegcrc3 195 14 PPI PPI NNP cord-285647-9tegcrc3 195 15 network network NN cord-285647-9tegcrc3 195 16 , , , cord-285647-9tegcrc3 195 17 we -PRON- PRP cord-285647-9tegcrc3 195 18 consider consider VBP cord-285647-9tegcrc3 195 19 the the DT cord-285647-9tegcrc3 195 20 solution solution NN cord-285647-9tegcrc3 195 21 of of IN cord-285647-9tegcrc3 195 22 the the DT cord-285647-9tegcrc3 195 23 TFD TFD NNP cord-285647-9tegcrc3 195 24 equation equation NN cord-285647-9tegcrc3 195 25 for for IN cord-285647-9tegcrc3 195 26 processes process NNS cord-285647-9tegcrc3 195 27 starting start VBG cord-285647-9tegcrc3 195 28 at at IN cord-285647-9tegcrc3 195 29 a a DT cord-285647-9tegcrc3 195 30 protein protein NN cord-285647-9tegcrc3 195 31 with with IN cord-285647-9tegcrc3 195 32 a a DT cord-285647-9tegcrc3 195 33 large large JJ cord-285647-9tegcrc3 195 34 degree degree NN cord-285647-9tegcrc3 195 35 , , , cord-285647-9tegcrc3 195 36 i.e. i.e. FW cord-285647-9tegcrc3 195 37 , , , cord-285647-9tegcrc3 195 38 PRKACA PRKACA NNP cord-285647-9tegcrc3 195 39 , , , cord-285647-9tegcrc3 195 40 degree degree NN cord-285647-9tegcrc3 195 41 14 14 CD cord-285647-9tegcrc3 195 42 , , , cord-285647-9tegcrc3 195 43 and and CC cord-285647-9tegcrc3 195 44 a a DT cord-285647-9tegcrc3 195 45 protein protein NN cord-285647-9tegcrc3 195 46 with with IN cord-285647-9tegcrc3 195 47 a a DT cord-285647-9tegcrc3 195 48 low low JJ cord-285647-9tegcrc3 195 49 degree degree NN cord-285647-9tegcrc3 195 50 , , , cord-285647-9tegcrc3 195 51 i.e. i.e. FW cord-285647-9tegcrc3 195 52 , , , cord-285647-9tegcrc3 195 53 MRPS5 mrps5 XX cord-285647-9tegcrc3 195 54 , , , cord-285647-9tegcrc3 195 55 degree degree NN cord-285647-9tegcrc3 195 56 3 3 CD cord-285647-9tegcrc3 195 57 . . . cord-285647-9tegcrc3 196 1 That that RB cord-285647-9tegcrc3 196 2 is is RB cord-285647-9tegcrc3 196 3 , , , cord-285647-9tegcrc3 196 4 the the DT cord-285647-9tegcrc3 196 5 initial initial JJ cord-285647-9tegcrc3 196 6 condition condition NN cord-285647-9tegcrc3 196 7 vector vector NN cord-285647-9tegcrc3 196 8 consists consist VBZ cord-285647-9tegcrc3 196 9 of of IN cord-285647-9tegcrc3 196 10 a a DT cord-285647-9tegcrc3 196 11 vector vector NN cord-285647-9tegcrc3 196 12 having have VBG cord-285647-9tegcrc3 196 13 one one CD cord-285647-9tegcrc3 196 14 at at IN cord-285647-9tegcrc3 196 15 the the DT cord-285647-9tegcrc3 196 16 entry entry NN cord-285647-9tegcrc3 196 17 corresponding correspond VBG cord-285647-9tegcrc3 196 18 to to IN cord-285647-9tegcrc3 196 19 either either CC cord-285647-9tegcrc3 196 20 PRKACA PRKACA NNP cord-285647-9tegcrc3 196 21 or or CC cord-285647-9tegcrc3 196 22 MRPS5 MRPS5 NNS cord-285647-9tegcrc3 196 23 and and CC cord-285647-9tegcrc3 196 24 zeroes zero NNS cord-285647-9tegcrc3 196 25 elsewhere elsewhere RB cord-285647-9tegcrc3 196 26 . . . cord-285647-9tegcrc3 197 1 In in IN cord-285647-9tegcrc3 197 2 Fig Fig NNP cord-285647-9tegcrc3 197 3 . . . cord-285647-9tegcrc3 198 1 1 1 LS cord-285647-9tegcrc3 198 2 , , , cord-285647-9tegcrc3 198 3 we -PRON- PRP cord-285647-9tegcrc3 198 4 display display VBP cord-285647-9tegcrc3 198 5 the the DT cord-285647-9tegcrc3 198 6 changes change NNS cord-285647-9tegcrc3 198 7 of of IN cord-285647-9tegcrc3 198 8 the the DT cord-285647-9tegcrc3 198 9 probability probability NN cord-285647-9tegcrc3 198 10 with with IN cord-285647-9tegcrc3 198 11 the the DT cord-285647-9tegcrc3 198 12 shortest short JJS cord-285647-9tegcrc3 198 13 path path NN cord-285647-9tegcrc3 198 14 distance distance NN cord-285647-9tegcrc3 198 15 from from IN cord-285647-9tegcrc3 198 16 the the DT cord-285647-9tegcrc3 198 17 protein protein NN cord-285647-9tegcrc3 198 18 where where WRB cord-285647-9tegcrc3 198 19 the the DT cord-285647-9tegcrc3 198 20 process process NN cord-285647-9tegcrc3 198 21 starts start VBZ cord-285647-9tegcrc3 198 22 . . . cord-285647-9tegcrc3 199 1 This this DT cord-285647-9tegcrc3 199 2 distance distance NN cord-285647-9tegcrc3 199 3 corresponds correspond VBZ cord-285647-9tegcrc3 199 4 to to IN cord-285647-9tegcrc3 199 5 the the DT cord-285647-9tegcrc3 199 6 number number NN cord-285647-9tegcrc3 199 7 of of IN cord-285647-9tegcrc3 199 8 steps step NNS cord-285647-9tegcrc3 199 9 that that WDT cord-285647-9tegcrc3 199 10 the the DT cord-285647-9tegcrc3 199 11 perturbation perturbation NN cord-285647-9tegcrc3 199 12 needs need VBZ cord-285647-9tegcrc3 199 13 to to TO cord-285647-9tegcrc3 199 14 traverse traverse VB cord-285647-9tegcrc3 199 15 to to TO cord-285647-9tegcrc3 199 16 visit visit VB cord-285647-9tegcrc3 199 17 other other JJ cord-285647-9tegcrc3 199 18 proteins protein NNS cord-285647-9tegcrc3 199 19 . . . cord-285647-9tegcrc3 200 1 For for IN cord-285647-9tegcrc3 200 2 α α NN cord-285647-9tegcrc3 200 3 = = SYM cord-285647-9tegcrc3 200 4 1.0 1.0 CD cord-285647-9tegcrc3 200 5 , , , cord-285647-9tegcrc3 200 6 the the DT cord-285647-9tegcrc3 200 7 shapes shape NNS cord-285647-9tegcrc3 200 8 of of IN cord-285647-9tegcrc3 200 9 the the DT cord-285647-9tegcrc3 200 10 curves curve NNS cord-285647-9tegcrc3 200 11 in in IN cord-285647-9tegcrc3 200 12 Fig Fig NNP cord-285647-9tegcrc3 200 13 . . . cord-285647-9tegcrc3 201 1 1 1 CD cord-285647-9tegcrc3 201 2 are be VBP cord-285647-9tegcrc3 201 3 the the DT cord-285647-9tegcrc3 201 4 characteristic characteristic JJ cord-285647-9tegcrc3 201 5 ones one NNS cord-285647-9tegcrc3 201 6 for for IN cord-285647-9tegcrc3 201 7 the the DT cord-285647-9tegcrc3 201 8 Gaussian gaussian JJ cord-285647-9tegcrc3 201 9 decay decay NN cord-285647-9tegcrc3 201 10 of of IN cord-285647-9tegcrc3 201 11 the the DT cord-285647-9tegcrc3 201 12 probability probability NN cord-285647-9tegcrc3 201 13 with with IN cord-285647-9tegcrc3 201 14 distance distance NN cord-285647-9tegcrc3 201 15 . . . cord-285647-9tegcrc3 202 1 However however RB cord-285647-9tegcrc3 202 2 , , , cord-285647-9tegcrc3 202 3 for for IN cord-285647-9tegcrc3 202 4 α α NN cord-285647-9tegcrc3 202 5 < < XX cord-285647-9tegcrc3 202 6 1 1 CD cord-285647-9tegcrc3 202 7 , , , cord-285647-9tegcrc3 202 8 we -PRON- PRP cord-285647-9tegcrc3 202 9 observe observe VBP cord-285647-9tegcrc3 202 10 that that IN cord-285647-9tegcrc3 202 11 such such JJ cord-285647-9tegcrc3 202 12 decay decay NN cord-285647-9tegcrc3 202 13 differs differ VBZ cord-285647-9tegcrc3 202 14 from from IN cord-285647-9tegcrc3 202 15 that that DT cord-285647-9tegcrc3 202 16 typical typical JJ cord-285647-9tegcrc3 202 17 shape shape NN cord-285647-9tegcrc3 202 18 showing show VBG cord-285647-9tegcrc3 202 19 a a DT cord-285647-9tegcrc3 202 20 faster fast JJR cord-285647-9tegcrc3 202 21 initial initial JJ cord-285647-9tegcrc3 202 22 decay decay NN cord-285647-9tegcrc3 202 23 followed follow VBN cord-285647-9tegcrc3 202 24 by by IN cord-285647-9tegcrc3 202 25 a a DT cord-285647-9tegcrc3 202 26 slower slow JJR cord-285647-9tegcrc3 202 27 one one CD cord-285647-9tegcrc3 202 28 . . . cord-285647-9tegcrc3 203 1 In in IN cord-285647-9tegcrc3 203 2 order order NN cord-285647-9tegcrc3 203 3 to to TO cord-285647-9tegcrc3 203 4 observe observe VB cord-285647-9tegcrc3 203 5 this this DT cord-285647-9tegcrc3 203 6 effect effect NN cord-285647-9tegcrc3 203 7 in in IN cord-285647-9tegcrc3 203 8 a a DT cord-285647-9tegcrc3 203 9 better well JJR cord-285647-9tegcrc3 203 10 way way NN cord-285647-9tegcrc3 203 11 , , , cord-285647-9tegcrc3 203 12 we -PRON- PRP cord-285647-9tegcrc3 203 13 zoomed zoom VBD cord-285647-9tegcrc3 203 14 the the DT cord-285647-9tegcrc3 203 15 region region NN cord-285647-9tegcrc3 203 16 of of IN cord-285647-9tegcrc3 203 17 distances distance NNS cord-285647-9tegcrc3 203 18 from from IN cord-285647-9tegcrc3 203 19 2 2 CD cord-285647-9tegcrc3 203 20 to to IN cord-285647-9tegcrc3 203 21 4 4 LS cord-285647-9tegcrc3 203 22 [ [ -LRB- cord-285647-9tegcrc3 203 23 see see VB cord-285647-9tegcrc3 203 24 Figs fig NNS cord-285647-9tegcrc3 203 25 . . . cord-285647-9tegcrc3 203 26 1(b 1(b CD cord-285647-9tegcrc3 203 27 ) ) -RRB- cord-285647-9tegcrc3 204 1 and and CC cord-285647-9tegcrc3 204 2 1(d 1(d LS cord-285647-9tegcrc3 204 3 ) ) -RRB- cord-285647-9tegcrc3 204 4 ] ] -RRB- cord-285647-9tegcrc3 204 5 . . . cord-285647-9tegcrc3 205 1 As as IN cord-285647-9tegcrc3 205 2 can can MD cord-285647-9tegcrc3 205 3 be be VB cord-285647-9tegcrc3 205 4 seen see VBN cord-285647-9tegcrc3 205 5 for for IN cord-285647-9tegcrc3 205 6 distances distance NNS cord-285647-9tegcrc3 205 7 below below IN cord-285647-9tegcrc3 205 8 3 3 CD cord-285647-9tegcrc3 205 9 , , , cord-285647-9tegcrc3 205 10 the the DT cord-285647-9tegcrc3 205 11 curve curve NN cord-285647-9tegcrc3 205 12 for for IN cord-285647-9tegcrc3 205 13 α α NN cord-285647-9tegcrc3 205 14 = = SYM cord-285647-9tegcrc3 205 15 1.0 1.0 CD cord-285647-9tegcrc3 205 16 is be VBZ cord-285647-9tegcrc3 205 17 on on IN cord-285647-9tegcrc3 205 18 top top NN cord-285647-9tegcrc3 205 19 of of IN cord-285647-9tegcrc3 205 20 those those DT cord-285647-9tegcrc3 205 21 for for IN cord-285647-9tegcrc3 205 22 α α NNP cord-285647-9tegcrc3 205 23 < < XX cord-285647-9tegcrc3 205 24 1 1 CD cord-285647-9tegcrc3 205 25 , , , cord-285647-9tegcrc3 205 26 indicating indicate VBG cord-285647-9tegcrc3 205 27 a a DT cord-285647-9tegcrc3 205 28 slower slow JJR cord-285647-9tegcrc3 205 29 decay decay NN cord-285647-9tegcrc3 205 30 of of IN cord-285647-9tegcrc3 205 31 the the DT cord-285647-9tegcrc3 205 32 probability probability NN cord-285647-9tegcrc3 205 33 . . . cord-285647-9tegcrc3 206 1 After after IN cord-285647-9tegcrc3 206 2 this this DT cord-285647-9tegcrc3 206 3 distance distance NN cord-285647-9tegcrc3 206 4 , , , cord-285647-9tegcrc3 206 5 there there EX cord-285647-9tegcrc3 206 6 is be VBZ cord-285647-9tegcrc3 206 7 an an DT cord-285647-9tegcrc3 206 8 inversion inversion NN cord-285647-9tegcrc3 206 9 , , , cord-285647-9tegcrc3 206 10 and and CC cord-285647-9tegcrc3 206 11 the the DT cord-285647-9tegcrc3 206 12 normal normal JJ cord-285647-9tegcrc3 206 13 diffusion diffusion NN cord-285647-9tegcrc3 206 14 occurs occur VBZ cord-285647-9tegcrc3 206 15 at at IN cord-285647-9tegcrc3 206 16 a a DT cord-285647-9tegcrc3 206 17 much much RB cord-285647-9tegcrc3 206 18 faster fast JJR cord-285647-9tegcrc3 206 19 rate rate NN cord-285647-9tegcrc3 206 20 than than IN cord-285647-9tegcrc3 206 21 the the DT cord-285647-9tegcrc3 206 22 other other JJ cord-285647-9tegcrc3 206 23 two two CD cord-285647-9tegcrc3 206 24 for for IN cord-285647-9tegcrc3 206 25 the the DT cord-285647-9tegcrc3 206 26 longer long JJR cord-285647-9tegcrc3 206 27 distances distance NNS cord-285647-9tegcrc3 206 28 . . . cord-285647-9tegcrc3 207 1 This this DT cord-285647-9tegcrc3 207 2 is be VBZ cord-285647-9tegcrc3 207 3 a a DT cord-285647-9tegcrc3 207 4 characteristic characteristic JJ cord-285647-9tegcrc3 207 5 signature signature NN cord-285647-9tegcrc3 207 6 of of IN cord-285647-9tegcrc3 207 7 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 207 8 processes process NNS cord-285647-9tegcrc3 207 9 , , , cord-285647-9tegcrc3 207 10 which which WDT cord-285647-9tegcrc3 207 11 starts start VBZ cord-285647-9tegcrc3 207 12 at at IN cord-285647-9tegcrc3 207 13 much much RB cord-285647-9tegcrc3 207 14 faster fast JJR cord-285647-9tegcrc3 207 15 rates rate NNS cord-285647-9tegcrc3 207 16 than than IN cord-285647-9tegcrc3 207 17 a a DT cord-285647-9tegcrc3 207 18 normal normal JJ cord-285647-9tegcrc3 207 19 diffusive diffusive JJ cord-285647-9tegcrc3 207 20 process process NN cord-285647-9tegcrc3 207 21 and and CC cord-285647-9tegcrc3 207 22 then then RB cord-285647-9tegcrc3 207 23 continue continue VB cord-285647-9tegcrc3 207 24 at at RB cord-285647-9tegcrc3 207 25 much much RB cord-285647-9tegcrc3 207 26 slower slow JJR cord-285647-9tegcrc3 207 27 rates rate NNS cord-285647-9tegcrc3 207 28 . . . cord-285647-9tegcrc3 208 1 Therefore therefore RB cord-285647-9tegcrc3 208 2 , , , cord-285647-9tegcrc3 208 3 here here RB cord-285647-9tegcrc3 208 4 , , , cord-285647-9tegcrc3 208 5 we -PRON- PRP cord-285647-9tegcrc3 208 6 observe observe VBP cord-285647-9tegcrc3 208 7 that that IN cord-285647-9tegcrc3 208 8 the the DT cord-285647-9tegcrc3 208 9 subdiffusive subdiffusive NNP cord-285647-9tegcrc3 208 10 dynamics dynamic NNS cord-285647-9tegcrc3 208 11 are be VBP cord-285647-9tegcrc3 208 12 much much RB cord-285647-9tegcrc3 208 13 faster fast JJR cord-285647-9tegcrc3 208 14 at at IN cord-285647-9tegcrc3 208 15 earlier early JJR cord-285647-9tegcrc3 208 16 times time NNS cord-285647-9tegcrc3 208 17 of of IN cord-285647-9tegcrc3 208 18 the the DT cord-285647-9tegcrc3 208 19 process process NN cord-285647-9tegcrc3 208 20 , , , cord-285647-9tegcrc3 208 21 which which WDT cord-285647-9tegcrc3 208 22 is be VBZ cord-285647-9tegcrc3 208 23 when when WRB cord-285647-9tegcrc3 208 24 the the DT cord-285647-9tegcrc3 208 25 perturbation perturbation NN cord-285647-9tegcrc3 208 26 occurs occur VBZ cord-285647-9tegcrc3 208 27 to to TO cord-285647-9tegcrc3 208 28 close close VB cord-285647-9tegcrc3 208 29 nearest near JJS cord-285647-9tegcrc3 208 30 neighbors neighbor NNS cord-285647-9tegcrc3 208 31 to to IN cord-285647-9tegcrc3 208 32 the the DT cord-285647-9tegcrc3 208 33 initial initial JJ cord-285647-9tegcrc3 208 34 point point NN cord-285647-9tegcrc3 208 35 of of IN cord-285647-9tegcrc3 208 36 perturbation perturbation NN cord-285647-9tegcrc3 208 37 . . . cord-285647-9tegcrc3 209 1 To to TO cord-285647-9tegcrc3 209 2 further further RB cord-285647-9tegcrc3 209 3 investigate investigate VB cord-285647-9tegcrc3 209 4 these these DT cord-285647-9tegcrc3 209 5 characteristic characteristic JJ cord-285647-9tegcrc3 209 6 effects effect NNS cord-285647-9tegcrc3 209 7 of of IN cord-285647-9tegcrc3 209 8 the the DT cord-285647-9tegcrc3 209 9 subdiffusive subdiffusive NNP cord-285647-9tegcrc3 209 10 dynamics dynamic NNS cord-285647-9tegcrc3 209 11 , , , cord-285647-9tegcrc3 209 12 we -PRON- PRP cord-285647-9tegcrc3 209 13 study study VBP cord-285647-9tegcrc3 209 14 the the DT cord-285647-9tegcrc3 209 15 time time NN cord-285647-9tegcrc3 209 16 evolution evolution NN cord-285647-9tegcrc3 209 17 of of IN cord-285647-9tegcrc3 209 18 a a DT cord-285647-9tegcrc3 209 19 perturbation perturbation NN cord-285647-9tegcrc3 209 20 occurring occur VBG cord-285647-9tegcrc3 209 21 at at IN cord-285647-9tegcrc3 209 22 a a DT cord-285647-9tegcrc3 209 23 given give VBN cord-285647-9tegcrc3 209 24 protein protein NN cord-285647-9tegcrc3 209 25 and and CC cord-285647-9tegcrc3 209 26 its -PRON- PRP$ cord-285647-9tegcrc3 209 27 propagation propagation NN cord-285647-9tegcrc3 209 28 across across IN cord-285647-9tegcrc3 209 29 the the DT cord-285647-9tegcrc3 209 30 whole whole JJ cord-285647-9tegcrc3 209 31 PPI PPI NNP cord-285647-9tegcrc3 209 32 network network NN cord-285647-9tegcrc3 209 33 . . . cord-285647-9tegcrc3 210 1 In in IN cord-285647-9tegcrc3 210 2 Fig Fig NNP cord-285647-9tegcrc3 210 3 . . . cord-285647-9tegcrc3 211 1 2 2 LS cord-285647-9tegcrc3 211 2 , , , cord-285647-9tegcrc3 211 3 we -PRON- PRP cord-285647-9tegcrc3 211 4 illustrate illustrate VBP cord-285647-9tegcrc3 211 5 these these DT cord-285647-9tegcrc3 211 6 results result NNS cord-285647-9tegcrc3 211 7 for for IN cord-285647-9tegcrc3 211 8 α α NN cord-285647-9tegcrc3 211 9 = = SYM cord-285647-9tegcrc3 211 10 1.0 1.0 CD cord-285647-9tegcrc3 211 11 ( ( -LRB- cord-285647-9tegcrc3 211 12 a a LS cord-285647-9tegcrc3 211 13 ) ) -RRB- cord-285647-9tegcrc3 211 14 , , , cord-285647-9tegcrc3 211 15 α α NN cord-285647-9tegcrc3 211 16 = = SYM cord-285647-9tegcrc3 211 17 0.75 0.75 CD cord-285647-9tegcrc3 211 18 ( ( -LRB- cord-285647-9tegcrc3 211 19 b b NN cord-285647-9tegcrc3 211 20 ) ) -RRB- cord-285647-9tegcrc3 211 21 , , , cord-285647-9tegcrc3 211 22 and and CC cord-285647-9tegcrc3 211 23 α α NN cord-285647-9tegcrc3 211 24 = = SYM cord-285647-9tegcrc3 211 25 0.5 0.5 CD cord-285647-9tegcrc3 211 26 ( ( -LRB- cord-285647-9tegcrc3 211 27 c c NN cord-285647-9tegcrc3 211 28 ) ) -RRB- cord-285647-9tegcrc3 211 29 . . . cord-285647-9tegcrc3 212 1 As as IN cord-285647-9tegcrc3 212 2 can can MD cord-285647-9tegcrc3 212 3 be be VB cord-285647-9tegcrc3 212 4 seen see VBN cord-285647-9tegcrc3 212 5 in in IN cord-285647-9tegcrc3 212 6 the the DT cord-285647-9tegcrc3 212 7 main main JJ cord-285647-9tegcrc3 212 8 plots plot NNS cord-285647-9tegcrc3 212 9 of of IN cord-285647-9tegcrc3 212 10 this this DT cord-285647-9tegcrc3 212 11 figure figure NN cord-285647-9tegcrc3 212 12 , , , cord-285647-9tegcrc3 212 13 the the DT cord-285647-9tegcrc3 212 14 rate rate NN cord-285647-9tegcrc3 212 15 of of IN cord-285647-9tegcrc3 212 16 convergence convergence NN cord-285647-9tegcrc3 212 17 of of IN cord-285647-9tegcrc3 212 18 the the DT cord-285647-9tegcrc3 212 19 processes process NNS cord-285647-9tegcrc3 212 20 to to IN cord-285647-9tegcrc3 212 21 the the DT cord-285647-9tegcrc3 212 22 steady steady JJ cord-285647-9tegcrc3 212 23 state state NN cord-285647-9tegcrc3 212 24 is be VBZ cord-285647-9tegcrc3 212 25 much much RB cord-285647-9tegcrc3 212 26 faster fast JJR cord-285647-9tegcrc3 212 27 in in IN cord-285647-9tegcrc3 212 28 the the DT cord-285647-9tegcrc3 212 29 normal normal JJ cord-285647-9tegcrc3 212 30 diffusion diffusion NN cord-285647-9tegcrc3 212 31 ( ( -LRB- cord-285647-9tegcrc3 212 32 a a LS cord-285647-9tegcrc3 212 33 ) ) -RRB- cord-285647-9tegcrc3 212 34 than than IN cord-285647-9tegcrc3 212 35 in in IN cord-285647-9tegcrc3 212 36 the the DT cord-285647-9tegcrc3 212 37 subdiffusive subdiffusive NNP cord-285647-9tegcrc3 212 38 one one NN cord-285647-9tegcrc3 212 39 ( ( -LRB- cord-285647-9tegcrc3 212 40 b b NN cord-285647-9tegcrc3 212 41 ) ) -RRB- cord-285647-9tegcrc3 212 42 and and CC cord-285647-9tegcrc3 212 43 ( ( -LRB- cord-285647-9tegcrc3 212 44 c c NN cord-285647-9tegcrc3 212 45 ) ) -RRB- cord-285647-9tegcrc3 212 46 . . . cord-285647-9tegcrc3 213 1 However however RB cord-285647-9tegcrc3 213 2 , , , cord-285647-9tegcrc3 213 3 at at IN cord-285647-9tegcrc3 213 4 very very RB cord-285647-9tegcrc3 213 5 earlier early JJR cord-285647-9tegcrc3 213 6 times time NNS cord-285647-9tegcrc3 213 7 ( ( -LRB- cord-285647-9tegcrc3 213 8 see see VBP cord-285647-9tegcrc3 213 9 insets inset NNS cord-285647-9tegcrc3 213 10 in in IN cord-285647-9tegcrc3 213 11 Fig Fig NNP cord-285647-9tegcrc3 213 12 . . NNP cord-285647-9tegcrc3 213 13 2 2 CD cord-285647-9tegcrc3 213 14 ) ) -RRB- cord-285647-9tegcrc3 213 15 , , , cord-285647-9tegcrc3 213 16 there there EX cord-285647-9tegcrc3 213 17 is be VBZ cord-285647-9tegcrc3 213 18 a a DT cord-285647-9tegcrc3 213 19 shock shock NN cord-285647-9tegcrc3 213 20 wave wave NN cord-285647-9tegcrc3 213 21 increase increase NN cord-285647-9tegcrc3 213 22 of of IN cord-285647-9tegcrc3 213 23 the the DT cord-285647-9tegcrc3 213 24 perturbation perturbation NN cord-285647-9tegcrc3 213 25 at at IN cord-285647-9tegcrc3 213 26 a a DT cord-285647-9tegcrc3 213 27 set set NN cord-285647-9tegcrc3 213 28 of of IN cord-285647-9tegcrc3 213 29 nodes node NNS cord-285647-9tegcrc3 213 30 . . . cord-285647-9tegcrc3 214 1 Such such JJ cord-285647-9tegcrc3 214 2 kind kind NN cord-285647-9tegcrc3 214 3 of of IN cord-285647-9tegcrc3 214 4 shock shock NN cord-285647-9tegcrc3 214 5 waves wave NNS cord-285647-9tegcrc3 214 6 has have VBZ cord-285647-9tegcrc3 214 7 been be VBN cord-285647-9tegcrc3 214 8 previously previously RB cord-285647-9tegcrc3 214 9 analyzed analyze VBN cord-285647-9tegcrc3 214 10 in in IN cord-285647-9tegcrc3 214 11 other other JJ cord-285647-9tegcrc3 214 12 contexts context NNS cord-285647-9tegcrc3 214 13 as as IN cord-285647-9tegcrc3 214 14 a a DT cord-285647-9tegcrc3 214 15 way way NN cord-285647-9tegcrc3 214 16 of of IN cord-285647-9tegcrc3 214 17 propagating propagate VBG cord-285647-9tegcrc3 214 18 effects effect NNS cord-285647-9tegcrc3 214 19 across across IN cord-285647-9tegcrc3 214 20 PPI PPI NNP cord-285647-9tegcrc3 214 21 networks network NNS cord-285647-9tegcrc3 214 22 . . . cord-285647-9tegcrc3 215 1 17 17 CD cord-285647-9tegcrc3 216 1 We -PRON- PRP cord-285647-9tegcrc3 216 2 have have VBP cord-285647-9tegcrc3 216 3 explored explore VBN cord-285647-9tegcrc3 216 4 briefly briefly RB cord-285647-9tegcrc3 216 5 about about IN cord-285647-9tegcrc3 216 6 the the DT cord-285647-9tegcrc3 216 7 possible possible JJ cord-285647-9tegcrc3 216 8 causes cause NNS cord-285647-9tegcrc3 216 9 of of IN cord-285647-9tegcrc3 216 10 this this DT cord-285647-9tegcrc3 216 11 increase increase NN cord-285647-9tegcrc3 216 12 in in IN cord-285647-9tegcrc3 216 13 the the DT cord-285647-9tegcrc3 216 14 concentration concentration NN cord-285647-9tegcrc3 216 15 for for IN cord-285647-9tegcrc3 216 16 a a DT cord-285647-9tegcrc3 216 17 given give VBN cord-285647-9tegcrc3 216 18 subset subset NN cord-285647-9tegcrc3 216 19 of of IN cord-285647-9tegcrc3 216 20 proteins protein NNS cord-285647-9tegcrc3 216 21 . . . cord-285647-9tegcrc3 217 1 Accordingly accordingly RB cord-285647-9tegcrc3 217 2 , , , cord-285647-9tegcrc3 217 3 it -PRON- PRP cord-285647-9tegcrc3 217 4 seems seem VBZ cord-285647-9tegcrc3 217 5 that that IN cord-285647-9tegcrc3 217 6 the the DT cord-285647-9tegcrc3 217 7 main main JJ cord-285647-9tegcrc3 217 8 reason reason NN cord-285647-9tegcrc3 217 9 for for IN cord-285647-9tegcrc3 217 10 this this DT cord-285647-9tegcrc3 217 11 is be VBZ cord-285647-9tegcrc3 217 12 the the DT cord-285647-9tegcrc3 217 13 connectivity connectivity NN cord-285647-9tegcrc3 217 14 provided provide VBN cord-285647-9tegcrc3 217 15 by by IN cord-285647-9tegcrc3 217 16 the the DT cord-285647-9tegcrc3 217 17 network network NN cord-285647-9tegcrc3 217 18 of of IN cord-285647-9tegcrc3 217 19 interactions interaction NNS cord-285647-9tegcrc3 217 20 and and CC cord-285647-9tegcrc3 217 21 not not RB cord-285647-9tegcrc3 217 22 a a DT cord-285647-9tegcrc3 217 23 given give VBN cord-285647-9tegcrc3 217 24 distribution distribution NN cord-285647-9tegcrc3 217 25 of of IN cord-285647-9tegcrc3 217 26 the the DT cord-285647-9tegcrc3 217 27 degrees degree NNS cord-285647-9tegcrc3 217 28 . . . cord-285647-9tegcrc3 218 1 For for IN cord-285647-9tegcrc3 218 2 instance instance NN cord-285647-9tegcrc3 218 3 , , , cord-285647-9tegcrc3 218 4 we -PRON- PRP cord-285647-9tegcrc3 218 5 have have VBP cord-285647-9tegcrc3 218 6 observed observe VBN cord-285647-9tegcrc3 218 7 such such JJ cord-285647-9tegcrc3 218 8 " " `` cord-285647-9tegcrc3 218 9 shock shock NN cord-285647-9tegcrc3 218 10 waves wave NNS cord-285647-9tegcrc3 218 11 " " '' cord-285647-9tegcrc3 218 12 in in IN cord-285647-9tegcrc3 218 13 networks network NNS cord-285647-9tegcrc3 218 14 with with IN cord-285647-9tegcrc3 218 15 normal normal JJ cord-285647-9tegcrc3 218 16 - - HYPH cord-285647-9tegcrc3 218 17 like like JJ cord-285647-9tegcrc3 218 18 distributions distribution NNS cord-285647-9tegcrc3 218 19 as as RB cord-285647-9tegcrc3 218 20 well well RB cord-285647-9tegcrc3 218 21 as as IN cord-285647-9tegcrc3 218 22 with with IN cord-285647-9tegcrc3 218 23 power power NN cord-285647-9tegcrc3 218 24 - - HYPH cord-285647-9tegcrc3 218 25 law law NN cord-285647-9tegcrc3 218 26 ones one NNS cord-285647-9tegcrc3 218 27 . . . cord-285647-9tegcrc3 219 1 However however RB cord-285647-9tegcrc3 219 2 , , , cord-285647-9tegcrc3 219 3 it -PRON- PRP cord-285647-9tegcrc3 219 4 is be VBZ cord-285647-9tegcrc3 219 5 possible possible JJ cord-285647-9tegcrc3 219 6 that that IN cord-285647-9tegcrc3 219 7 the the DT cord-285647-9tegcrc3 219 8 extension extension NN cord-285647-9tegcrc3 219 9 and and CC cord-285647-9tegcrc3 219 10 intensity intensity NN cord-285647-9tegcrc3 219 11 of of IN cord-285647-9tegcrc3 219 12 such such JJ cord-285647-9tegcrc3 219 13 effects effect NNS cord-285647-9tegcrc3 219 14 depend depend VBP cord-285647-9tegcrc3 219 15 on on IN cord-285647-9tegcrc3 219 16 the the DT cord-285647-9tegcrc3 219 17 degree degree NN cord-285647-9tegcrc3 219 18 distribution distribution NN cord-285647-9tegcrc3 219 19 as as RB cord-285647-9tegcrc3 219 20 well well RB cord-285647-9tegcrc3 219 21 as as IN cord-285647-9tegcrc3 219 22 on on IN cord-285647-9tegcrc3 219 23 other other JJ cord-285647-9tegcrc3 219 24 topological topological JJ cord-285647-9tegcrc3 219 25 factors factor NNS cord-285647-9tegcrc3 219 26 . . . cord-285647-9tegcrc3 220 1 The the DT cord-285647-9tegcrc3 220 2 remarkable remarkable JJ cord-285647-9tegcrc3 220 3 finding finding NN cord-285647-9tegcrc3 220 4 here here RB cord-285647-9tegcrc3 220 5 is be VBZ cord-285647-9tegcrc3 220 6 , , , cord-285647-9tegcrc3 220 7 however however RB cord-285647-9tegcrc3 220 8 , , , cord-285647-9tegcrc3 220 9 the the DT cord-285647-9tegcrc3 220 10 fact fact NN cord-285647-9tegcrc3 220 11 that that IN cord-285647-9tegcrc3 220 12 such such PDT cord-285647-9tegcrc3 220 13 a a DT cord-285647-9tegcrc3 220 14 shock shock NN cord-285647-9tegcrc3 220 15 wave wave NN cord-285647-9tegcrc3 220 16 occurs occur VBZ cord-285647-9tegcrc3 220 17 at at RB cord-285647-9tegcrc3 220 18 much much RB cord-285647-9tegcrc3 220 19 earlier early JJR cord-285647-9tegcrc3 220 20 times time NNS cord-285647-9tegcrc3 220 21 in in IN cord-285647-9tegcrc3 220 22 the the DT cord-285647-9tegcrc3 220 23 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 220 24 regimes regime NNS cord-285647-9tegcrc3 220 25 than than IN cord-285647-9tegcrc3 220 26 at at IN cord-285647-9tegcrc3 220 27 the the DT cord-285647-9tegcrc3 220 28 normal normal JJ cord-285647-9tegcrc3 220 29 diffusion diffusion NN cord-285647-9tegcrc3 220 30 . . . cord-285647-9tegcrc3 221 1 That that RB cord-285647-9tegcrc3 221 2 is is RB cord-285647-9tegcrc3 221 3 , , , cord-285647-9tegcrc3 221 4 while while IN cord-285647-9tegcrc3 221 5 for for IN cord-285647-9tegcrc3 221 6 α α NN cord-285647-9tegcrc3 221 7 = = SYM cord-285647-9tegcrc3 221 8 1.0 1.0 CD cord-285647-9tegcrc3 221 9 , , , cord-285647-9tegcrc3 221 10 these these DT cord-285647-9tegcrc3 221 11 perturbations perturbation NNS cord-285647-9tegcrc3 221 12 occur occur VBP cord-285647-9tegcrc3 221 13 at at IN cord-285647-9tegcrc3 221 14 t≈0.1 t≈0.1 CD cord-285647-9tegcrc3 221 15 - - HYPH cord-285647-9tegcrc3 221 16 0.3 0.3 CD cord-285647-9tegcrc3 221 17 ; ; : cord-285647-9tegcrc3 221 18 for for IN cord-285647-9tegcrc3 221 19 α α NN cord-285647-9tegcrc3 221 20 = = SYM cord-285647-9tegcrc3 221 21 0.75 0.75 CD cord-285647-9tegcrc3 221 22 , , , cord-285647-9tegcrc3 221 23 they -PRON- PRP cord-285647-9tegcrc3 221 24 occur occur VBP cord-285647-9tegcrc3 221 25 at at IN cord-285647-9tegcrc3 221 26 t≈0.0 t≈0.0 CD cord-285647-9tegcrc3 221 27 - - HYPH cord-285647-9tegcrc3 221 28 0.2 0.2 CD cord-285647-9tegcrc3 221 29 ; ; : cord-285647-9tegcrc3 221 30 and and CC cord-285647-9tegcrc3 221 31 for for IN cord-285647-9tegcrc3 221 32 α α NN cord-285647-9tegcrc3 221 33 = = SYM cord-285647-9tegcrc3 221 34 0.5 0.5 CD cord-285647-9tegcrc3 221 35 , , , cord-285647-9tegcrc3 221 36 they -PRON- PRP cord-285647-9tegcrc3 221 37 occur occur VBP cord-285647-9tegcrc3 221 38 at at IN cord-285647-9tegcrc3 221 39 t≈0.0 t≈0.0 CD cord-285647-9tegcrc3 221 40 - - SYM cord-285647-9tegcrc3 221 41 0.1 0.1 CD cord-285647-9tegcrc3 221 42 . . . cord-285647-9tegcrc3 222 1 Seeing see VBG cord-285647-9tegcrc3 222 2 this this DT cord-285647-9tegcrc3 222 3 phenomenon phenomenon NN cord-285647-9tegcrc3 222 4 in in IN cord-285647-9tegcrc3 222 5 the the DT cord-285647-9tegcrc3 222 6 light light NN cord-285647-9tegcrc3 222 7 of of IN cord-285647-9tegcrc3 222 8 what what WP cord-285647-9tegcrc3 222 9 we -PRON- PRP cord-285647-9tegcrc3 222 10 have have VBP cord-285647-9tegcrc3 222 11 observed observe VBN cord-285647-9tegcrc3 222 12 in in IN cord-285647-9tegcrc3 222 13 the the DT cord-285647-9tegcrc3 222 14 previous previous JJ cord-285647-9tegcrc3 222 15 paragraph paragraph NN cord-285647-9tegcrc3 222 16 is be VBZ cord-285647-9tegcrc3 222 17 not not RB cord-285647-9tegcrc3 222 18 strange strange JJ cord-285647-9tegcrc3 222 19 due due IN cord-285647-9tegcrc3 222 20 to to IN cord-285647-9tegcrc3 222 21 the the DT cord-285647-9tegcrc3 222 22 observation observation NN cord-285647-9tegcrc3 222 23 that that IN cord-285647-9tegcrc3 222 24 such such JJ cord-285647-9tegcrc3 222 25 processes process NNS cord-285647-9tegcrc3 222 26 go go VBP cord-285647-9tegcrc3 222 27 at at IN cord-285647-9tegcrc3 222 28 a a DT cord-285647-9tegcrc3 222 29 much much RB cord-285647-9tegcrc3 222 30 faster fast JJR cord-285647-9tegcrc3 222 31 rate rate NN cord-285647-9tegcrc3 222 32 at at IN cord-285647-9tegcrc3 222 33 earlier early JJR cord-285647-9tegcrc3 222 34 times time NNS cord-285647-9tegcrc3 222 35 , , , cord-285647-9tegcrc3 222 36 and and CC cord-285647-9tegcrc3 222 37 at at IN cord-285647-9tegcrc3 222 38 short short JJ cord-285647-9tegcrc3 222 39 distances distance NNS cord-285647-9tegcrc3 222 40 , , , cord-285647-9tegcrc3 222 41 than than IN cord-285647-9tegcrc3 222 42 the the DT cord-285647-9tegcrc3 222 43 normal normal JJ cord-285647-9tegcrc3 222 44 diffusion diffusion NN cord-285647-9tegcrc3 222 45 . . . cord-285647-9tegcrc3 223 1 In in IN cord-285647-9tegcrc3 223 2 fact fact NN cord-285647-9tegcrc3 223 3 , , , cord-285647-9tegcrc3 223 4 this this DT cord-285647-9tegcrc3 223 5 is be VBZ cord-285647-9tegcrc3 223 6 a a DT cord-285647-9tegcrc3 223 7 consequence consequence NN cord-285647-9tegcrc3 223 8 of of IN cord-285647-9tegcrc3 223 9 the the DT cord-285647-9tegcrc3 223 10 existence existence NN cord-285647-9tegcrc3 223 11 of of IN cord-285647-9tegcrc3 223 12 a a DT cord-285647-9tegcrc3 223 13 positive positive JJ cord-285647-9tegcrc3 223 14 scalar scalar JJ cord-285647-9tegcrc3 223 15 T t NN cord-285647-9tegcrc3 223 16 for for IN cord-285647-9tegcrc3 223 17 which which WDT cord-285647-9tegcrc3 223 18 E e NN cord-285647-9tegcrc3 223 19 α,1 α,1 FW cord-285647-9tegcrc3 223 20 ( ( -LRB- cord-285647-9tegcrc3 223 21 −γ −γ JJ cord-285647-9tegcrc3 223 22 t t NN cord-285647-9tegcrc3 223 23 α α NN cord-285647-9tegcrc3 223 24 ) ) -RRB- cord-285647-9tegcrc3 223 25 decreases decrease VBZ cord-285647-9tegcrc3 223 26 faster fast RBR cord-285647-9tegcrc3 223 27 than than IN cord-285647-9tegcrc3 223 28 exp exp NN cord-285647-9tegcrc3 223 29 ( ( -LRB- cord-285647-9tegcrc3 223 30 −γ −γ NNP cord-285647-9tegcrc3 223 31 t t NNP cord-285647-9tegcrc3 223 32 ) ) -RRB- cord-285647-9tegcrc3 223 33 for for IN cord-285647-9tegcrc3 223 34 t t NN cord-285647-9tegcrc3 223 35 ∈ ∈ NN cord-285647-9tegcrc3 223 36 ( ( -LRB- cord-285647-9tegcrc3 223 37 0 0 NFP cord-285647-9tegcrc3 223 38 , , , cord-285647-9tegcrc3 223 39 T T NNP cord-285647-9tegcrc3 223 40 ) ) -RRB- cord-285647-9tegcrc3 223 41 for for IN cord-285647-9tegcrc3 223 42 γ γ NN cord-285647-9tegcrc3 223 43 ∈ ∈ NN cord-285647-9tegcrc3 223 44 R r NN cord-285647-9tegcrc3 223 45 + + CC cord-285647-9tegcrc3 223 46 and and CC cord-285647-9tegcrc3 223 47 α α NN cord-285647-9tegcrc3 223 48 ∈ ∈ NN cord-285647-9tegcrc3 223 49 R r NN cord-285647-9tegcrc3 224 1 + + CC cord-285647-9tegcrc3 224 2 ( ( -LRB- cord-285647-9tegcrc3 224 3 see see VB cord-285647-9tegcrc3 225 1 Theorem theorem NN cord-285647-9tegcrc3 225 2 4.1 4.1 CD cord-285647-9tegcrc3 225 3 in in IN cord-285647-9tegcrc3 225 4 Ref Ref NNP cord-285647-9tegcrc3 225 5 . . . cord-285647-9tegcrc3 225 6 39 39 CD cord-285647-9tegcrc3 225 7 ) ) -RRB- cord-285647-9tegcrc3 225 8 . . . cord-285647-9tegcrc3 226 1 Hereafter hereafter RB cord-285647-9tegcrc3 226 2 , , , cord-285647-9tegcrc3 226 3 we -PRON- PRP cord-285647-9tegcrc3 226 4 will will MD cord-285647-9tegcrc3 226 5 consider consider VB cord-285647-9tegcrc3 226 6 the the DT cord-285647-9tegcrc3 226 7 value value NN cord-285647-9tegcrc3 226 8 of of IN cord-285647-9tegcrc3 226 9 α α NN cord-285647-9tegcrc3 226 10 = = SYM cord-285647-9tegcrc3 226 11 0.75 0.75 CD cord-285647-9tegcrc3 226 12 for for IN cord-285647-9tegcrc3 226 13 our -PRON- PRP$ cord-285647-9tegcrc3 226 14 experiments experiment NNS cord-285647-9tegcrc3 226 15 due due JJ cord-285647-9tegcrc3 226 16 to to IN cord-285647-9tegcrc3 226 17 the the DT cord-285647-9tegcrc3 226 18 fact fact NN cord-285647-9tegcrc3 226 19 that that IN cord-285647-9tegcrc3 226 20 it -PRON- PRP cord-285647-9tegcrc3 226 21 reveals reveal VBZ cord-285647-9tegcrc3 226 22 a a DT cord-285647-9tegcrc3 226 23 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 226 24 regime regime NN cord-285647-9tegcrc3 226 25 , , , cord-285647-9tegcrc3 226 26 but but CC cord-285647-9tegcrc3 226 27 the the DT cord-285647-9tegcrc3 226 28 shock shock NN cord-285647-9tegcrc3 226 29 waves wave NNS cord-285647-9tegcrc3 226 30 observed observe VBD cord-285647-9tegcrc3 226 31 before before RB cord-285647-9tegcrc3 226 32 are be VBP cord-285647-9tegcrc3 226 33 not not RB cord-285647-9tegcrc3 226 34 occurring occur VBG cord-285647-9tegcrc3 226 35 in in IN cord-285647-9tegcrc3 226 36 an an DT cord-285647-9tegcrc3 226 37 almost almost RB cord-285647-9tegcrc3 226 38 instantaneous instantaneous JJ cord-285647-9tegcrc3 226 39 way way NN cord-285647-9tegcrc3 226 40 like like UH cord-285647-9tegcrc3 226 41 when when WRB cord-285647-9tegcrc3 226 42 α α NN cord-285647-9tegcrc3 226 43 = = SYM cord-285647-9tegcrc3 226 44 0.5 0.5 CD cord-285647-9tegcrc3 226 45 , , , cord-285647-9tegcrc3 226 46 which which WDT cord-285647-9tegcrc3 226 47 would would MD cord-285647-9tegcrc3 226 48 be be VB cord-285647-9tegcrc3 226 49 difficult difficult JJ cord-285647-9tegcrc3 226 50 from from IN cord-285647-9tegcrc3 226 51 a a DT cord-285647-9tegcrc3 226 52 biological biological JJ cord-285647-9tegcrc3 226 53 perspective perspective NN cord-285647-9tegcrc3 226 54 . . . cord-285647-9tegcrc3 227 1 The the DT cord-285647-9tegcrc3 227 2 previous previous JJ cord-285647-9tegcrc3 227 3 results result NNS cord-285647-9tegcrc3 227 4 put put VBD cord-285647-9tegcrc3 227 5 us -PRON- PRP cord-285647-9tegcrc3 227 6 at at IN cord-285647-9tegcrc3 227 7 a a DT cord-285647-9tegcrc3 227 8 crossroads crossroad NNS cord-285647-9tegcrc3 227 9 . . . cord-285647-9tegcrc3 228 1 First first RB cord-285647-9tegcrc3 228 2 , , , cord-285647-9tegcrc3 228 3 the the DT cord-285647-9tegcrc3 228 4 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 228 5 processes process NNS cord-285647-9tegcrc3 228 6 that that WDT cord-285647-9tegcrc3 228 7 are be VBP cord-285647-9tegcrc3 228 8 expected expect VBN cord-285647-9tegcrc3 228 9 due due IN cord-285647-9tegcrc3 228 10 to to IN cord-285647-9tegcrc3 228 11 the the DT cord-285647-9tegcrc3 228 12 crowded crowded JJ cord-285647-9tegcrc3 228 13 nature nature NN cord-285647-9tegcrc3 228 14 of of IN cord-285647-9tegcrc3 228 15 the the DT cord-285647-9tegcrc3 228 16 intra intra JJ cord-285647-9tegcrc3 228 17 - - JJ cord-285647-9tegcrc3 228 18 cellular cellular JJ cord-285647-9tegcrc3 228 19 space space NN cord-285647-9tegcrc3 228 20 are be VBP cord-285647-9tegcrc3 228 21 very very RB cord-285647-9tegcrc3 228 22 slow slow JJ cord-285647-9tegcrc3 228 23 for for IN cord-285647-9tegcrc3 228 24 carrying carry VBG cord-285647-9tegcrc3 228 25 out out RP cord-285647-9tegcrc3 228 26 cellular cellular JJ cord-285647-9tegcrc3 228 27 processes process NNS cord-285647-9tegcrc3 228 28 at at IN cord-285647-9tegcrc3 228 29 a a DT cord-285647-9tegcrc3 228 30 significant significant JJ cord-285647-9tegcrc3 228 31 rate rate NN cord-285647-9tegcrc3 228 32 in in IN cord-285647-9tegcrc3 228 33 cells cell NNS cord-285647-9tegcrc3 228 34 . . . cord-285647-9tegcrc3 229 1 However however RB cord-285647-9tegcrc3 229 2 , , , cord-285647-9tegcrc3 229 3 the the DT cord-285647-9tegcrc3 229 4 perturbation perturbation NN cord-285647-9tegcrc3 229 5 shocks shock NNS cord-285647-9tegcrc3 229 6 occurring occur VBG cord-285647-9tegcrc3 229 7 at at IN cord-285647-9tegcrc3 229 8 earlier early JJR cord-285647-9tegcrc3 229 9 times time NNS cord-285647-9tegcrc3 229 10 of of IN cord-285647-9tegcrc3 229 11 these these DT cord-285647-9tegcrc3 229 12 processes process NNS cord-285647-9tegcrc3 229 13 are be VBP cord-285647-9tegcrc3 229 14 significantly significantly RB cord-285647-9tegcrc3 229 15 faster fast JJR cord-285647-9tegcrc3 229 16 than than IN cord-285647-9tegcrc3 229 17 in in IN cord-285647-9tegcrc3 229 18 normal normal JJ cord-285647-9tegcrc3 229 19 diffusion diffusion NN cord-285647-9tegcrc3 229 20 . . . cord-285647-9tegcrc3 230 1 To to TO cord-285647-9tegcrc3 230 2 sort sort VB cord-285647-9tegcrc3 230 3 out out RP cord-285647-9tegcrc3 230 4 these these DT cord-285647-9tegcrc3 230 5 difficulties difficulty NNS cord-285647-9tegcrc3 230 6 , , , cord-285647-9tegcrc3 230 7 we -PRON- PRP cord-285647-9tegcrc3 230 8 propose propose VBP cord-285647-9tegcrc3 230 9 a a DT cord-285647-9tegcrc3 230 10 switching switching NN cord-285647-9tegcrc3 230 11 back back RB cord-285647-9tegcrc3 230 12 and and CC cord-285647-9tegcrc3 230 13 restart restart VB cord-285647-9tegcrc3 230 14 subdiffusive subdiffusive NN cord-285647-9tegcrc3 230 15 process process NN cord-285647-9tegcrc3 230 16 occurring occur VBG cord-285647-9tegcrc3 230 17 in in IN cord-285647-9tegcrc3 230 18 the the DT cord-285647-9tegcrc3 230 19 PPI PPI NNP cord-285647-9tegcrc3 230 20 network network NN cord-285647-9tegcrc3 230 21 . . . cord-285647-9tegcrc3 231 1 That that RB cord-285647-9tegcrc3 231 2 is is RB cord-285647-9tegcrc3 231 3 , , , cord-285647-9tegcrc3 231 4 a a DT cord-285647-9tegcrc3 231 5 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 231 6 process process NN cord-285647-9tegcrc3 231 7 starts start VBZ cord-285647-9tegcrc3 231 8 at at IN cord-285647-9tegcrc3 231 9 a a DT cord-285647-9tegcrc3 231 10 given give VBN cord-285647-9tegcrc3 231 11 protein protein NN cord-285647-9tegcrc3 231 12 , , , cord-285647-9tegcrc3 231 13 which which WDT cord-285647-9tegcrc3 231 14 is be VBZ cord-285647-9tegcrc3 231 15 directly directly RB cord-285647-9tegcrc3 231 16 perturbed perturb VBN cord-285647-9tegcrc3 231 17 by by IN cord-285647-9tegcrc3 231 18 a a DT cord-285647-9tegcrc3 231 19 protein protein NN cord-285647-9tegcrc3 231 20 of of IN cord-285647-9tegcrc3 231 21 SARS SARS NNP cord-285647-9tegcrc3 231 22 - - HYPH cord-285647-9tegcrc3 231 23 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 231 24 . . . cord-285647-9tegcrc3 232 1 It -PRON- PRP cord-285647-9tegcrc3 232 2 produces produce VBZ cord-285647-9tegcrc3 232 3 a a DT cord-285647-9tegcrc3 232 4 shock shock NN cord-285647-9tegcrc3 232 5 wave wave NN cord-285647-9tegcrc3 232 6 increase increase NN cord-285647-9tegcrc3 232 7 of of IN cord-285647-9tegcrc3 232 8 the the DT cord-285647-9tegcrc3 232 9 perturbation perturbation NN cord-285647-9tegcrc3 232 10 in in IN cord-285647-9tegcrc3 232 11 close close JJ cord-285647-9tegcrc3 232 12 neighbors neighbor NNS cord-285647-9tegcrc3 232 13 of of IN cord-285647-9tegcrc3 232 14 that that DT cord-285647-9tegcrc3 232 15 proteins protein NNS cord-285647-9tegcrc3 232 16 . . . cord-285647-9tegcrc3 233 1 Then then RB cord-285647-9tegcrc3 233 2 , , , cord-285647-9tegcrc3 233 3 a a DT cord-285647-9tegcrc3 233 4 second second JJ cord-285647-9tegcrc3 233 5 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 233 6 process process NN cord-285647-9tegcrc3 233 7 starts start VBZ cord-285647-9tegcrc3 233 8 at at IN cord-285647-9tegcrc3 233 9 these these DT cord-285647-9tegcrc3 233 10 newly newly RB cord-285647-9tegcrc3 233 11 perturbed perturb VBN cord-285647-9tegcrc3 233 12 proteins protein NNS cord-285647-9tegcrc3 233 13 , , , cord-285647-9tegcrc3 233 14 which which WDT cord-285647-9tegcrc3 233 15 will will MD cord-285647-9tegcrc3 233 16 perturb perturb VB cord-285647-9tegcrc3 233 17 their -PRON- PRP$ cord-285647-9tegcrc3 233 18 nearest near JJS cord-285647-9tegcrc3 233 19 neighbors neighbor NNS cord-285647-9tegcrc3 233 20 . . . cord-285647-9tegcrc3 234 1 The the DT cord-285647-9tegcrc3 234 2 process process NN cord-285647-9tegcrc3 234 3 is be VBZ cord-285647-9tegcrc3 234 4 repeated repeat VBN cord-285647-9tegcrc3 234 5 until until IN cord-285647-9tegcrc3 234 6 the the DT cord-285647-9tegcrc3 234 7 whole whole JJ cord-285647-9tegcrc3 234 8 PPI PPI NNP cord-285647-9tegcrc3 234 9 network network NN cord-285647-9tegcrc3 234 10 is be VBZ cord-285647-9tegcrc3 234 11 perturbed perturb VBN cord-285647-9tegcrc3 234 12 . . . cord-285647-9tegcrc3 235 1 This this DT cord-285647-9tegcrc3 235 2 kind kind NN cord-285647-9tegcrc3 235 3 of of IN cord-285647-9tegcrc3 235 4 " " `` cord-285647-9tegcrc3 235 5 switch switch VB cord-285647-9tegcrc3 235 6 and and CC cord-285647-9tegcrc3 235 7 restart restart VB cord-285647-9tegcrc3 235 8 processes process NNS cord-285647-9tegcrc3 235 9 " " `` cord-285647-9tegcrc3 235 10 has have VBZ cord-285647-9tegcrc3 235 11 been be VBN cord-285647-9tegcrc3 235 12 proposed propose VBN cord-285647-9tegcrc3 235 13 for for IN cord-285647-9tegcrc3 235 14 engineering engineering NN cord-285647-9tegcrc3 235 15 consensus consensus NN cord-285647-9tegcrc3 235 16 protocols protocol NNS cord-285647-9tegcrc3 235 17 in in IN cord-285647-9tegcrc3 235 18 multiagent multiagent NN cord-285647-9tegcrc3 235 19 systems system NNS cord-285647-9tegcrc3 235 20 51 51 CD cord-285647-9tegcrc3 235 21 as as IN cord-285647-9tegcrc3 235 22 a a DT cord-285647-9tegcrc3 235 23 way way NN cord-285647-9tegcrc3 235 24 to to TO cord-285647-9tegcrc3 235 25 accelerate accelerate VB cord-285647-9tegcrc3 235 26 the the DT cord-285647-9tegcrc3 235 27 algorithms algorithm NNS cord-285647-9tegcrc3 235 28 using use VBG cord-285647-9tegcrc3 235 29 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 235 30 regimes regime NNS cord-285647-9tegcrc3 235 31 . . . cord-285647-9tegcrc3 236 1 The the DT cord-285647-9tegcrc3 236 2 so so RB cord-285647-9tegcrc3 236 3 - - HYPH cord-285647-9tegcrc3 236 4 called call VBN cord-285647-9tegcrc3 236 5 Spike Spike NNP cord-285647-9tegcrc3 236 6 protein protein NN cord-285647-9tegcrc3 236 7 ( ( -LRB- cord-285647-9tegcrc3 236 8 S s NN cord-285647-9tegcrc3 236 9 - - HYPH cord-285647-9tegcrc3 236 10 protein protein NN cord-285647-9tegcrc3 236 11 ) ) -RRB- cord-285647-9tegcrc3 236 12 of of IN cord-285647-9tegcrc3 236 13 the the DT cord-285647-9tegcrc3 236 14 SARS SARS NNP cord-285647-9tegcrc3 236 15 - - HYPH cord-285647-9tegcrc3 236 16 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 236 17 interacts interact VBZ cord-285647-9tegcrc3 236 18 with with IN cord-285647-9tegcrc3 236 19 only only RB cord-285647-9tegcrc3 236 20 two two CD cord-285647-9tegcrc3 236 21 proteins protein NNS cord-285647-9tegcrc3 236 22 in in IN cord-285647-9tegcrc3 236 23 the the DT cord-285647-9tegcrc3 236 24 human human JJ cord-285647-9tegcrc3 236 25 hosts host NNS cord-285647-9tegcrc3 236 26 , , , cord-285647-9tegcrc3 236 27 namely namely RB cord-285647-9tegcrc3 236 28 , , , cord-285647-9tegcrc3 236 29 ZDHHC5 ZDHHC5 NNP cord-285647-9tegcrc3 236 30 and and CC cord-285647-9tegcrc3 236 31 GOLGA7 GOLGA7 NNP cord-285647-9tegcrc3 236 32 . . . cord-285647-9tegcrc3 237 1 The the DT cord-285647-9tegcrc3 237 2 first first JJ cord-285647-9tegcrc3 237 3 protein protein NN cord-285647-9tegcrc3 237 4 , , , cord-285647-9tegcrc3 237 5 ZDHHC5 ZDHHC5 NNS cord-285647-9tegcrc3 237 6 , , , cord-285647-9tegcrc3 237 7 is be VBZ cord-285647-9tegcrc3 237 8 not not RB cord-285647-9tegcrc3 237 9 in in IN cord-285647-9tegcrc3 237 10 the the DT cord-285647-9tegcrc3 237 11 main main JJ cord-285647-9tegcrc3 237 12 connected connected JJ cord-285647-9tegcrc3 237 13 component component NN cord-285647-9tegcrc3 237 14 of of IN cord-285647-9tegcrc3 237 15 the the DT cord-285647-9tegcrc3 237 16 PPI PPI NNP cord-285647-9tegcrc3 237 17 network network NN cord-285647-9tegcrc3 237 18 of of IN cord-285647-9tegcrc3 237 19 SARS SARS NNP cord-285647-9tegcrc3 237 20 - - HYPH cord-285647-9tegcrc3 237 21 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 237 22 targets target NNS cord-285647-9tegcrc3 237 23 . . . cord-285647-9tegcrc3 238 1 Therefore therefore RB cord-285647-9tegcrc3 238 2 , , , cord-285647-9tegcrc3 238 3 we -PRON- PRP cord-285647-9tegcrc3 238 4 will will MD cord-285647-9tegcrc3 238 5 consider consider VB cord-285647-9tegcrc3 238 6 here here RB cord-285647-9tegcrc3 238 7 how how WRB cord-285647-9tegcrc3 238 8 a a DT cord-285647-9tegcrc3 238 9 perturbation perturbation NN cord-285647-9tegcrc3 238 10 produced produce VBN cord-285647-9tegcrc3 238 11 by by IN cord-285647-9tegcrc3 238 12 the the DT cord-285647-9tegcrc3 238 13 interaction interaction NN cord-285647-9tegcrc3 238 14 of of IN cord-285647-9tegcrc3 238 15 the the DT cord-285647-9tegcrc3 238 16 virus virus NN cord-285647-9tegcrc3 238 17 S s NN cord-285647-9tegcrc3 238 18 - - HYPH cord-285647-9tegcrc3 238 19 protein protein NN cord-285647-9tegcrc3 238 20 with with IN cord-285647-9tegcrc3 238 21 GOLGA7 GOLGA7 NNP cord-285647-9tegcrc3 238 22 is be VBZ cord-285647-9tegcrc3 238 23 propagated propagate VBN cord-285647-9tegcrc3 238 24 through through IN cord-285647-9tegcrc3 238 25 the the DT cord-285647-9tegcrc3 238 26 whole whole JJ cord-285647-9tegcrc3 238 27 PPI PPI NNP cord-285647-9tegcrc3 238 28 network network NN cord-285647-9tegcrc3 238 29 of of IN cord-285647-9tegcrc3 238 30 SARS SARS NNP cord-285647-9tegcrc3 238 31 - - HYPH cord-285647-9tegcrc3 238 32 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 238 33 targets target NNS cord-285647-9tegcrc3 238 34 . . . cord-285647-9tegcrc3 239 1 GOLGA7 GOLGA7 NNP cord-285647-9tegcrc3 239 2 has have VBZ cord-285647-9tegcrc3 239 3 degree degree NN cord-285647-9tegcrc3 239 4 one one CD cord-285647-9tegcrc3 239 5 in in IN cord-285647-9tegcrc3 239 6 this this DT cord-285647-9tegcrc3 239 7 network network NN cord-285647-9tegcrc3 239 8 , , , cord-285647-9tegcrc3 239 9 and and CC cord-285647-9tegcrc3 239 10 its -PRON- PRP$ cord-285647-9tegcrc3 239 11 diffusion diffusion NN cord-285647-9tegcrc3 239 12 is be VBZ cord-285647-9tegcrc3 239 13 mainly mainly RB cord-285647-9tegcrc3 239 14 to to TO cord-285647-9tegcrc3 239 15 close close VB cord-285647-9tegcrc3 239 16 neighbors neighbor NNS cord-285647-9tegcrc3 239 17 , , , cord-285647-9tegcrc3 239 18 namely namely RB cord-285647-9tegcrc3 239 19 , , , cord-285647-9tegcrc3 239 20 to to IN cord-285647-9tegcrc3 239 21 proteins protein NNS cord-285647-9tegcrc3 239 22 separated separate VBN cord-285647-9tegcrc3 239 23 by by IN cord-285647-9tegcrc3 239 24 two two CD cord-285647-9tegcrc3 239 25 to to TO cord-285647-9tegcrc3 239 26 three three CD cord-285647-9tegcrc3 239 27 edges edge NNS cord-285647-9tegcrc3 239 28 . . . cord-285647-9tegcrc3 240 1 When when WRB cord-285647-9tegcrc3 240 2 starting start VBG cord-285647-9tegcrc3 240 3 the the DT cord-285647-9tegcrc3 240 4 diffusion diffusion NN cord-285647-9tegcrc3 240 5 process process NN cord-285647-9tegcrc3 240 6 at at IN cord-285647-9tegcrc3 240 7 the the DT cord-285647-9tegcrc3 240 8 protein protein NN cord-285647-9tegcrc3 240 9 GOLGA7 GOLGA7 NNP cord-285647-9tegcrc3 240 10 , , , cord-285647-9tegcrc3 240 11 the the DT cord-285647-9tegcrc3 240 12 main main JJ cord-285647-9tegcrc3 240 13 increase increase NN cord-285647-9tegcrc3 240 14 in in IN cord-285647-9tegcrc3 240 15 the the DT cord-285647-9tegcrc3 240 16 probability probability NN cord-285647-9tegcrc3 240 17 of of IN cord-285647-9tegcrc3 240 18 perturbing perturb VBG cord-285647-9tegcrc3 240 19 another another DT cord-285647-9tegcrc3 240 20 protein protein NN cord-285647-9tegcrc3 240 21 is be VBZ cord-285647-9tegcrc3 240 22 reached reach VBN cord-285647-9tegcrc3 240 23 for for IN cord-285647-9tegcrc3 240 24 the the DT cord-285647-9tegcrc3 240 25 protein protein NN cord-285647-9tegcrc3 240 26 GOLGA3 GOLGA3 NNP cord-285647-9tegcrc3 240 27 , , , cord-285647-9tegcrc3 240 28 which which WDT cord-285647-9tegcrc3 240 29 increases increase VBZ cord-285647-9tegcrc3 240 30 its -PRON- PRP$ cord-285647-9tegcrc3 240 31 probability probability NN cord-285647-9tegcrc3 240 32 up up IN cord-285647-9tegcrc3 240 33 to to IN cord-285647-9tegcrc3 240 34 0.15 0.15 CD cord-285647-9tegcrc3 240 35 at at IN cord-285647-9tegcrc3 240 36 t t NN cord-285647-9tegcrc3 240 37 = = SYM cord-285647-9tegcrc3 240 38 0.2 0.2 CD cord-285647-9tegcrc3 240 39 , , , cord-285647-9tegcrc3 240 40 followed follow VBN cord-285647-9tegcrc3 240 41 by by IN cord-285647-9tegcrc3 240 42 PRKAR2A PRKAR2A NNP cord-285647-9tegcrc3 240 43 , , , cord-285647-9tegcrc3 240 44 with with IN cord-285647-9tegcrc3 240 45 a a DT cord-285647-9tegcrc3 240 46 small small JJ cord-285647-9tegcrc3 240 47 increase increase NN cord-285647-9tegcrc3 240 48 in in IN cord-285647-9tegcrc3 240 49 its -PRON- PRP$ cord-285647-9tegcrc3 240 50 probability probability NN cord-285647-9tegcrc3 240 51 , , , cord-285647-9tegcrc3 240 52 0.0081 0.0081 CD cord-285647-9tegcrc3 240 53 . . . cord-285647-9tegcrc3 241 1 Then then RB cord-285647-9tegcrc3 241 2 , , , cord-285647-9tegcrc3 241 3 the the DT cord-285647-9tegcrc3 241 4 process process NN cord-285647-9tegcrc3 241 5 switch switch NN cord-285647-9tegcrc3 241 6 and and CC cord-285647-9tegcrc3 241 7 restarts restart VBZ cord-285647-9tegcrc3 241 8 at at IN cord-285647-9tegcrc3 241 9 GOLGA3 GOLGA3 NNP cord-285647-9tegcrc3 241 10 , , , cord-285647-9tegcrc3 241 11 which which WDT cord-285647-9tegcrc3 241 12 mainly mainly RB cord-285647-9tegcrc3 241 13 triggers trigger VBZ cord-285647-9tegcrc3 241 14 the the DT cord-285647-9tegcrc3 241 15 probability probability NN cord-285647-9tegcrc3 241 16 of of IN cord-285647-9tegcrc3 241 17 the the DT cord-285647-9tegcrc3 241 18 protein protein NN cord-285647-9tegcrc3 242 1 PRKAR2A prkar2a RB cord-285647-9tegcrc3 242 2 - - HYPH cord-285647-9tegcrc3 242 3 a a DT cord-285647-9tegcrc3 242 4 major major JJ cord-285647-9tegcrc3 242 5 hub hub NN cord-285647-9tegcrc3 242 6 of of IN cord-285647-9tegcrc3 242 7 the the DT cord-285647-9tegcrc3 242 8 network network NN cord-285647-9tegcrc3 242 9 . . . cord-285647-9tegcrc3 243 1 Once once IN cord-285647-9tegcrc3 243 2 we -PRON- PRP cord-285647-9tegcrc3 243 3 start start VBP cord-285647-9tegcrc3 243 4 the the DT cord-285647-9tegcrc3 243 5 process process NN cord-285647-9tegcrc3 243 6 at at IN cord-285647-9tegcrc3 243 7 PRKAR2A prkar2a NN cord-285647-9tegcrc3 243 8 , , , cord-285647-9tegcrc3 243 9 practically practically RB cord-285647-9tegcrc3 243 10 , , , cord-285647-9tegcrc3 243 11 the the DT cord-285647-9tegcrc3 243 12 whole whole JJ cord-285647-9tegcrc3 243 13 network network NN cord-285647-9tegcrc3 243 14 is be VBZ cord-285647-9tegcrc3 243 15 perturbed perturb VBN cord-285647-9tegcrc3 243 16 with with IN cord-285647-9tegcrc3 243 17 probabilities probability NNS cord-285647-9tegcrc3 243 18 larger large JJR cord-285647-9tegcrc3 243 19 than than IN cord-285647-9tegcrc3 243 20 0.1 0.1 CD cord-285647-9tegcrc3 243 21 for for IN cord-285647-9tegcrc3 243 22 19 19 CD cord-285647-9tegcrc3 243 23 proteins protein NNS cord-285647-9tegcrc3 243 24 apart apart RB cord-285647-9tegcrc3 243 25 from from IN cord-285647-9tegcrc3 243 26 GOLGA3 golga3 NN cord-285647-9tegcrc3 243 27 . . . cord-285647-9tegcrc3 244 1 These these DT cord-285647-9tegcrc3 244 2 proteins protein NNS cord-285647-9tegcrc3 244 3 are be VBP cord-285647-9tegcrc3 244 4 in in IN cord-285647-9tegcrc3 244 5 decreasing decrease VBG cord-285647-9tegcrc3 244 6 order order NN cord-285647-9tegcrc3 244 7 of of IN cord-285647-9tegcrc3 244 8 their -PRON- PRP$ cord-285647-9tegcrc3 244 9 probability probability NN cord-285647-9tegcrc3 244 10 of of IN cord-285647-9tegcrc3 244 11 being be VBG cord-285647-9tegcrc3 244 12 perturbed perturb VBN cord-285647-9tegcrc3 244 13 : : : cord-285647-9tegcrc3 244 14 AKAP8 akap8 ADD cord-285647-9tegcrc3 244 15 , , , cord-285647-9tegcrc3 244 16 PRKAR2B PRKAR2B NNP cord-285647-9tegcrc3 244 17 , , , cord-285647-9tegcrc3 244 18 CEP350 CEP350 NNP cord-285647-9tegcrc3 244 19 , , , cord-285647-9tegcrc3 244 20 MIB1 MIB1 NNP cord-285647-9tegcrc3 244 21 , , , cord-285647-9tegcrc3 244 22 CDK5RAP2 CDK5RAP2 NNP cord-285647-9tegcrc3 244 23 , , , cord-285647-9tegcrc3 244 24 CEP135 CEP135 NNP cord-285647-9tegcrc3 244 25 , , , cord-285647-9tegcrc3 244 26 AKAP9 AKAP9 NNS cord-285647-9tegcrc3 244 27 , , , cord-285647-9tegcrc3 244 28 CEP250 CEP250 NNP cord-285647-9tegcrc3 244 29 , , , cord-285647-9tegcrc3 244 30 PCNT PCNT NNP cord-285647-9tegcrc3 244 31 , , , cord-285647-9tegcrc3 244 32 CEP43 CEP43 NNP cord-285647-9tegcrc3 244 33 , , , cord-285647-9tegcrc3 244 34 PDE4DIP PDE4DIP NNP cord-285647-9tegcrc3 244 35 , , , cord-285647-9tegcrc3 244 36 PRKACA PRKACA NNP cord-285647-9tegcrc3 244 37 , , , cord-285647-9tegcrc3 244 38 TUB6CP3 tub6cp3 NN cord-285647-9tegcrc3 244 39 , , , cord-285647-9tegcrc3 244 40 TUB6CP2 TUB6CP2 NNP cord-285647-9tegcrc3 244 41 , , , cord-285647-9tegcrc3 244 42 CEP68 CEP68 NNP cord-285647-9tegcrc3 244 43 , , , cord-285647-9tegcrc3 244 44 CLIP4 CLIP4 NNP cord-285647-9tegcrc3 244 45 , , , cord-285647-9tegcrc3 244 46 CNTRL CNTRL NNP cord-285647-9tegcrc3 244 47 , , , cord-285647-9tegcrc3 244 48 PLEKHA5 PLEKHA5 NNP cord-285647-9tegcrc3 244 49 , , , cord-285647-9tegcrc3 244 50 and and CC cord-285647-9tegcrc3 244 51 NINL NINL NNP cord-285647-9tegcrc3 244 52 . . . cord-285647-9tegcrc3 245 1 Notice notice VB cord-285647-9tegcrc3 245 2 that that IN cord-285647-9tegcrc3 245 3 the the DT cord-285647-9tegcrc3 245 4 number number NN cord-285647-9tegcrc3 245 5 of of IN cord-285647-9tegcrc3 245 6 proteins protein NNS cord-285647-9tegcrc3 245 7 perturbed perturb VBN cord-285647-9tegcrc3 245 8 is be VBZ cord-285647-9tegcrc3 245 9 significantly significantly RB cord-285647-9tegcrc3 245 10 larger large JJR cord-285647-9tegcrc3 245 11 than than IN cord-285647-9tegcrc3 245 12 the the DT cord-285647-9tegcrc3 245 13 degree degree NN cord-285647-9tegcrc3 245 14 of of IN cord-285647-9tegcrc3 245 15 the the DT cord-285647-9tegcrc3 245 16 activator activator NN cord-285647-9tegcrc3 245 17 , , , cord-285647-9tegcrc3 245 18 indicating indicate VBG cord-285647-9tegcrc3 245 19 that that IN cord-285647-9tegcrc3 245 20 not not RB cord-285647-9tegcrc3 245 21 only only RB cord-285647-9tegcrc3 245 22 nearest near JJS cord-285647-9tegcrc3 245 23 neighbors neighbor NNS cord-285647-9tegcrc3 245 24 are be VBP cord-285647-9tegcrc3 245 25 activated activate VBN cord-285647-9tegcrc3 245 26 . . . cord-285647-9tegcrc3 246 1 An an DT cord-285647-9tegcrc3 246 2 important important JJ cord-285647-9tegcrc3 246 3 criterion criterion NN cord-285647-9tegcrc3 246 4 for for IN cord-285647-9tegcrc3 246 5 revealing reveal VBG cord-285647-9tegcrc3 246 6 the the DT cord-285647-9tegcrc3 246 7 important important JJ cord-285647-9tegcrc3 246 8 role role NN cord-285647-9tegcrc3 246 9 of of IN cord-285647-9tegcrc3 246 10 the the DT cord-285647-9tegcrc3 246 11 protein protein NN cord-285647-9tegcrc3 246 12 PRKAR2A prkar2a RB cord-285647-9tegcrc3 246 13 as as IN cord-285647-9tegcrc3 246 14 a a DT cord-285647-9tegcrc3 246 15 main main JJ cord-285647-9tegcrc3 246 16 propagator propagator NN cord-285647-9tegcrc3 246 17 in in IN cord-285647-9tegcrc3 246 18 the the DT cord-285647-9tegcrc3 246 19 network network NN cord-285647-9tegcrc3 246 20 of of IN cord-285647-9tegcrc3 246 21 proteins protein NNS cord-285647-9tegcrc3 246 22 targeted target VBN cord-285647-9tegcrc3 246 23 by by IN cord-285647-9tegcrc3 246 24 SARS SARS NNP cord-285647-9tegcrc3 246 25 - - HYPH cord-285647-9tegcrc3 246 26 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 246 27 is be VBZ cord-285647-9tegcrc3 246 28 its -PRON- PRP$ cord-285647-9tegcrc3 246 29 average average JJ cord-285647-9tegcrc3 246 30 diffusion diffusion NN cord-285647-9tegcrc3 246 31 path path NN cord-285647-9tegcrc3 246 32 length length NN cord-285647-9tegcrc3 246 33 . . . cord-285647-9tegcrc3 247 1 This this DT cord-285647-9tegcrc3 247 2 is be VBZ cord-285647-9tegcrc3 247 3 the the DT cord-285647-9tegcrc3 247 4 average average JJ cord-285647-9tegcrc3 247 5 number number NN cord-285647-9tegcrc3 247 6 of of IN cord-285647-9tegcrc3 247 7 steps step NNS cord-285647-9tegcrc3 247 8 that that WDT cord-285647-9tegcrc3 247 9 a a DT cord-285647-9tegcrc3 247 10 diffusive diffusive JJ cord-285647-9tegcrc3 247 11 process process NN cord-285647-9tegcrc3 247 12 starting start VBG cord-285647-9tegcrc3 247 13 at at IN cord-285647-9tegcrc3 247 14 this this DT cord-285647-9tegcrc3 247 15 protein protein NN cord-285647-9tegcrc3 247 16 needs need VBZ cord-285647-9tegcrc3 247 17 to to TO cord-285647-9tegcrc3 247 18 perturb perturb VB cord-285647-9tegcrc3 247 19 all all PDT cord-285647-9tegcrc3 247 20 the the DT cord-285647-9tegcrc3 247 21 proteins protein NNS cord-285647-9tegcrc3 247 22 in in IN cord-285647-9tegcrc3 247 23 the the DT cord-285647-9tegcrc3 247 24 network network NN cord-285647-9tegcrc3 247 25 . . . cord-285647-9tegcrc3 248 1 We -PRON- PRP cord-285647-9tegcrc3 248 2 have have VBP cord-285647-9tegcrc3 248 3 calculated calculate VBN cord-285647-9tegcrc3 248 4 this this DT cord-285647-9tegcrc3 248 5 number number NN cord-285647-9tegcrc3 248 6 to to TO cord-285647-9tegcrc3 248 7 be be VB cord-285647-9tegcrc3 248 8 3.6250 3.6250 CD cord-285647-9tegcrc3 248 9 , , , cord-285647-9tegcrc3 248 10 which which WDT cord-285647-9tegcrc3 248 11 is be VBZ cord-285647-9tegcrc3 248 12 only only RB cord-285647-9tegcrc3 248 13 slightly slightly RB cord-285647-9tegcrc3 248 14 larger large JJR cord-285647-9tegcrc3 248 15 than than IN cord-285647-9tegcrc3 248 16 the the DT cord-285647-9tegcrc3 248 17 average average JJ cord-285647-9tegcrc3 248 18 ( ( -LRB- cord-285647-9tegcrc3 248 19 topological topological JJ cord-285647-9tegcrc3 248 20 ) ) -RRB- cord-285647-9tegcrc3 248 21 path path NN cord-285647-9tegcrc3 248 22 length length NN cord-285647-9tegcrc3 248 23 , , , cord-285647-9tegcrc3 248 24 which which WDT cord-285647-9tegcrc3 248 25 is be VBZ cord-285647-9tegcrc3 248 26 3.5673 3.5673 CD cord-285647-9tegcrc3 248 27 . . . cord-285647-9tegcrc3 249 1 That that RB cord-285647-9tegcrc3 249 2 is is RB cord-285647-9tegcrc3 249 3 , , , cord-285647-9tegcrc3 249 4 in in IN cord-285647-9tegcrc3 249 5 less less JJR cord-285647-9tegcrc3 249 6 than than IN cord-285647-9tegcrc3 249 7 four four CD cord-285647-9tegcrc3 249 8 steps step NNS cord-285647-9tegcrc3 249 9 , , , cord-285647-9tegcrc3 249 10 the the DT cord-285647-9tegcrc3 249 11 whole whole JJ cord-285647-9tegcrc3 249 12 network network NN cord-285647-9tegcrc3 249 13 of of IN cord-285647-9tegcrc3 249 14 proteins protein NNS cord-285647-9tegcrc3 249 15 is be VBZ cord-285647-9tegcrc3 249 16 activated activate VBN cord-285647-9tegcrc3 249 17 by by IN cord-285647-9tegcrc3 249 18 a a DT cord-285647-9tegcrc3 249 19 diffusive diffusive JJ cord-285647-9tegcrc3 249 20 process process NN cord-285647-9tegcrc3 249 21 starting start VBG cord-285647-9tegcrc3 249 22 at at IN cord-285647-9tegcrc3 249 23 PRKAR2A. PRKAR2A. NNP cord-285647-9tegcrc3 249 24 Also also RB cord-285647-9tegcrc3 249 25 remarkable remarkable JJ cord-285647-9tegcrc3 249 26 that that IN cord-285647-9tegcrc3 249 27 the the DT cord-285647-9tegcrc3 249 28 average average JJ cord-285647-9tegcrc3 249 29 shortest short JJS cord-285647-9tegcrc3 249 30 diffusive diffusive JJ cord-285647-9tegcrc3 249 31 path path NN cord-285647-9tegcrc3 249 32 length length NN cord-285647-9tegcrc3 249 33 is be VBZ cord-285647-9tegcrc3 249 34 almost almost RB cord-285647-9tegcrc3 249 35 identical identical JJ cord-285647-9tegcrc3 249 36 to to IN cord-285647-9tegcrc3 249 37 the the DT cord-285647-9tegcrc3 249 38 shortest short JJS cord-285647-9tegcrc3 249 39 ( ( -LRB- cord-285647-9tegcrc3 249 40 topological topological JJ cord-285647-9tegcrc3 249 41 ) ) -RRB- cord-285647-9tegcrc3 249 42 one one CD cord-285647-9tegcrc3 249 43 . . . cord-285647-9tegcrc3 250 1 This this DT cord-285647-9tegcrc3 250 2 means mean VBZ cord-285647-9tegcrc3 250 3 that that IN cord-285647-9tegcrc3 250 4 this this DT cord-285647-9tegcrc3 250 5 protein protein NN cord-285647-9tegcrc3 250 6 mainly mainly RB cord-285647-9tegcrc3 250 7 uses use VBZ cord-285647-9tegcrc3 250 8 shortest short JJS cord-285647-9tegcrc3 250 9 ( ( -LRB- cord-285647-9tegcrc3 250 10 topological topological JJ cord-285647-9tegcrc3 250 11 ) ) -RRB- cord-285647-9tegcrc3 250 12 paths path NNS cord-285647-9tegcrc3 250 13 in in IN cord-285647-9tegcrc3 250 14 perturbing perturb VBG cord-285647-9tegcrc3 250 15 other other JJ cord-285647-9tegcrc3 250 16 proteins protein NNS cord-285647-9tegcrc3 250 17 in in IN cord-285647-9tegcrc3 250 18 the the DT cord-285647-9tegcrc3 250 19 PPI PPI NNP cord-285647-9tegcrc3 250 20 . . . cord-285647-9tegcrc3 251 1 In in IN cord-285647-9tegcrc3 251 2 other other JJ cord-285647-9tegcrc3 251 3 words word NNS cord-285647-9tegcrc3 251 4 , , , cord-285647-9tegcrc3 251 5 it -PRON- PRP cord-285647-9tegcrc3 251 6 is be VBZ cord-285647-9tegcrc3 251 7 highly highly RB cord-285647-9tegcrc3 251 8 efficient efficient JJ cord-285647-9tegcrc3 251 9 in in IN cord-285647-9tegcrc3 251 10 conducting conduct VBG cord-285647-9tegcrc3 251 11 such such JJ cord-285647-9tegcrc3 251 12 perturbations perturbation NNS cord-285647-9tegcrc3 251 13 . . . cord-285647-9tegcrc3 252 1 We -PRON- PRP cord-285647-9tegcrc3 252 2 will will MD cord-285647-9tegcrc3 252 3 analyze analyze VB cord-285647-9tegcrc3 252 4 this this DT cord-285647-9tegcrc3 252 5 characteristics characteristic NNS cord-285647-9tegcrc3 252 6 of of IN cord-285647-9tegcrc3 252 7 the the DT cord-285647-9tegcrc3 252 8 PPI PPI NNP cord-285647-9tegcrc3 252 9 of of IN cord-285647-9tegcrc3 252 10 human human JJ cord-285647-9tegcrc3 252 11 proteins protein NNS cord-285647-9tegcrc3 252 12 targeted target VBN cord-285647-9tegcrc3 252 13 by by IN cord-285647-9tegcrc3 252 14 SARS SARS NNP cord-285647-9tegcrc3 252 15 - - HYPH cord-285647-9tegcrc3 252 16 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 252 17 in in IN cord-285647-9tegcrc3 252 18 a a DT cord-285647-9tegcrc3 252 19 further further JJ cord-285647-9tegcrc3 252 20 section section NN cord-285647-9tegcrc3 252 21 of of IN cord-285647-9tegcrc3 252 22 this this DT cord-285647-9tegcrc3 252 23 work work NN cord-285647-9tegcrc3 252 24 . . . cord-285647-9tegcrc3 253 1 At at IN cord-285647-9tegcrc3 253 2 this this DT cord-285647-9tegcrc3 253 3 time time NN cord-285647-9tegcrc3 253 4 , , , cord-285647-9tegcrc3 253 5 almost almost RB cord-285647-9tegcrc3 253 6 any any DT cord-285647-9tegcrc3 253 7 protein protein NN cord-285647-9tegcrc3 253 8 in in IN cord-285647-9tegcrc3 253 9 the the DT cord-285647-9tegcrc3 253 10 PPI PPI NNP cord-285647-9tegcrc3 253 11 network network NN cord-285647-9tegcrc3 253 12 is be VBZ cord-285647-9tegcrc3 253 13 already already RB cord-285647-9tegcrc3 253 14 perturbed perturb VBN cord-285647-9tegcrc3 253 15 . . . cord-285647-9tegcrc3 254 1 Therefore therefore RB cord-285647-9tegcrc3 254 2 , , , cord-285647-9tegcrc3 254 3 we -PRON- PRP cord-285647-9tegcrc3 254 4 can can MD cord-285647-9tegcrc3 254 5 switch switch VB cord-285647-9tegcrc3 254 6 and and CC cord-285647-9tegcrc3 254 7 restart restart VB cord-285647-9tegcrc3 254 8 the the DT cord-285647-9tegcrc3 254 9 subdiffusion subdiffusion NN cord-285647-9tegcrc3 254 10 from from IN cord-285647-9tegcrc3 254 11 practically practically RB cord-285647-9tegcrc3 254 12 any any DT cord-285647-9tegcrc3 254 13 protein protein NN cord-285647-9tegcrc3 254 14 at at IN cord-285647-9tegcrc3 254 15 the the DT cord-285647-9tegcrc3 254 16 PPI PPI NNP cord-285647-9tegcrc3 254 17 network network NN cord-285647-9tegcrc3 254 18 . . . cord-285647-9tegcrc3 255 1 We -PRON- PRP cord-285647-9tegcrc3 255 2 then then RB cord-285647-9tegcrc3 255 3 investigate investigate VBP cord-285647-9tegcrc3 255 4 which which WDT cord-285647-9tegcrc3 255 5 are be VBP cord-285647-9tegcrc3 255 6 the the DT cord-285647-9tegcrc3 255 7 proteins protein NNS cord-285647-9tegcrc3 255 8 with with IN cord-285647-9tegcrc3 255 9 the the DT cord-285647-9tegcrc3 255 10 higher high JJR cord-285647-9tegcrc3 255 11 capacity capacity NN cord-285647-9tegcrc3 255 12 of of IN cord-285647-9tegcrc3 255 13 activating activate VBG cord-285647-9tegcrc3 255 14 other other JJ cord-285647-9tegcrc3 255 15 proteins protein NNS cord-285647-9tegcrc3 255 16 that that WDT cord-285647-9tegcrc3 255 17 are be VBP cord-285647-9tegcrc3 255 18 involved involve VBN cord-285647-9tegcrc3 255 19 in in IN cord-285647-9tegcrc3 255 20 human human JJ cord-285647-9tegcrc3 255 21 diseases disease NNS cord-285647-9tegcrc3 255 22 . . . cord-285647-9tegcrc3 256 1 Here here RB cord-285647-9tegcrc3 256 2 , , , cord-285647-9tegcrc3 256 3 we -PRON- PRP cord-285647-9tegcrc3 256 4 use use VBP cord-285647-9tegcrc3 256 5 the the DT cord-285647-9tegcrc3 256 6 database database NN cord-285647-9tegcrc3 256 7 DisGeNet disgenet NN cord-285647-9tegcrc3 256 8 , , , cord-285647-9tegcrc3 256 9 52 52 CD cord-285647-9tegcrc3 256 10 which which WDT cord-285647-9tegcrc3 256 11 is be VBZ cord-285647-9tegcrc3 256 12 one one CD cord-285647-9tegcrc3 256 13 of of IN cord-285647-9tegcrc3 256 14 the the DT cord-285647-9tegcrc3 256 15 largest large JJS cord-285647-9tegcrc3 256 16 publicly publicly RB cord-285647-9tegcrc3 256 17 available available JJ cord-285647-9tegcrc3 256 18 collections collection NNS cord-285647-9tegcrc3 256 19 of of IN cord-285647-9tegcrc3 256 20 genes gene NNS cord-285647-9tegcrc3 256 21 and and CC cord-285647-9tegcrc3 256 22 variants variant NNS cord-285647-9tegcrc3 256 23 associated associate VBN cord-285647-9tegcrc3 256 24 with with IN cord-285647-9tegcrc3 256 25 human human JJ cord-285647-9tegcrc3 256 26 diseases disease NNS cord-285647-9tegcrc3 256 27 . . . cord-285647-9tegcrc3 257 1 We -PRON- PRP cord-285647-9tegcrc3 257 2 identified identify VBD cord-285647-9tegcrc3 257 3 38 38 CD cord-285647-9tegcrc3 257 4 proteins protein NNS cord-285647-9tegcrc3 257 5 targeted target VBN cord-285647-9tegcrc3 257 6 by by IN cord-285647-9tegcrc3 257 7 SARS SARS NNP cord-285647-9tegcrc3 257 8 - - HYPH cord-285647-9tegcrc3 257 9 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 257 10 for for IN cord-285647-9tegcrc3 257 11 which which WDT cord-285647-9tegcrc3 257 12 there there EX cord-285647-9tegcrc3 257 13 is be VBZ cord-285647-9tegcrc3 257 14 a a DT cord-285647-9tegcrc3 257 15 " " `` cord-285647-9tegcrc3 257 16 definitive definitive JJ cord-285647-9tegcrc3 257 17 " " '' cord-285647-9tegcrc3 257 18 or or CC cord-285647-9tegcrc3 257 19 " " `` cord-285647-9tegcrc3 257 20 strong strong JJ cord-285647-9tegcrc3 257 21 " " '' cord-285647-9tegcrc3 257 22 evidence evidence NN cord-285647-9tegcrc3 257 23 of of IN cord-285647-9tegcrc3 257 24 being be VBG cord-285647-9tegcrc3 257 25 involved involve VBN cord-285647-9tegcrc3 257 26 in in IN cord-285647-9tegcrc3 257 27 a a DT cord-285647-9tegcrc3 257 28 human human JJ cord-285647-9tegcrc3 257 29 disease disease NN cord-285647-9tegcrc3 257 30 or or CC cord-285647-9tegcrc3 257 31 syndrome syndrome NN cord-285647-9tegcrc3 257 32 ( ( -LRB- cord-285647-9tegcrc3 257 33 see see VB cord-285647-9tegcrc3 257 34 Table Table NNP cord-285647-9tegcrc3 257 35 S1 S1 NNP cord-285647-9tegcrc3 257 36 in in IN cord-285647-9tegcrc3 257 37 the the DT cord-285647-9tegcrc3 257 38 supplementary supplementary JJ cord-285647-9tegcrc3 257 39 material material NN cord-285647-9tegcrc3 257 40 ) ) -RRB- cord-285647-9tegcrc3 257 41 . . . cord-285647-9tegcrc3 258 1 These these DT cord-285647-9tegcrc3 258 2 proteins protein NNS cord-285647-9tegcrc3 258 3 participate participate VBP cord-285647-9tegcrc3 258 4 in in IN cord-285647-9tegcrc3 258 5 70 70 CD cord-285647-9tegcrc3 258 6 different different JJ cord-285647-9tegcrc3 258 7 human human JJ cord-285647-9tegcrc3 258 8 diseases disease NNS cord-285647-9tegcrc3 258 9 or or CC cord-285647-9tegcrc3 258 10 syndromes syndrome NNS cord-285647-9tegcrc3 258 11 as as IN cord-285647-9tegcrc3 258 12 given give VBN cord-285647-9tegcrc3 258 13 in in IN cord-285647-9tegcrc3 258 14 Tables Tables NNP cord-285647-9tegcrc3 258 15 S2 S2 NNP cord-285647-9tegcrc3 258 16 and and CC cord-285647-9tegcrc3 258 17 S3 S3 NNP cord-285647-9tegcrc3 258 18 of of IN cord-285647-9tegcrc3 258 19 the the DT cord-285647-9tegcrc3 258 20 supplementary supplementary JJ cord-285647-9tegcrc3 258 21 material material NN cord-285647-9tegcrc3 258 22 . . . cord-285647-9tegcrc3 259 1 We -PRON- PRP cord-285647-9tegcrc3 259 2 performed perform VBD cord-285647-9tegcrc3 259 3 an an DT cord-285647-9tegcrc3 259 4 analysis analysis NN cord-285647-9tegcrc3 259 5 in in IN cord-285647-9tegcrc3 259 6 which which WDT cord-285647-9tegcrc3 259 7 a a DT cord-285647-9tegcrc3 259 8 diffusive diffusive JJ cord-285647-9tegcrc3 259 9 process process NN cord-285647-9tegcrc3 259 10 starts start VBZ cord-285647-9tegcrc3 259 11 at at IN cord-285647-9tegcrc3 259 12 any any DT cord-285647-9tegcrc3 259 13 protein protein NN cord-285647-9tegcrc3 259 14 of of IN cord-285647-9tegcrc3 259 15 the the DT cord-285647-9tegcrc3 259 16 network network NN cord-285647-9tegcrc3 259 17 , , , cord-285647-9tegcrc3 259 18 and and CC cord-285647-9tegcrc3 259 19 we -PRON- PRP cord-285647-9tegcrc3 259 20 calculated calculate VBD cord-285647-9tegcrc3 259 21 the the DT cord-285647-9tegcrc3 259 22 average average JJ cord-285647-9tegcrc3 259 23 probability probability NN cord-285647-9tegcrc3 259 24 that that IN cord-285647-9tegcrc3 259 25 all all PDT cord-285647-9tegcrc3 259 26 the the DT cord-285647-9tegcrc3 259 27 proteins protein NNS cord-285647-9tegcrc3 259 28 involved involve VBN cord-285647-9tegcrc3 259 29 in in IN cord-285647-9tegcrc3 259 30 human human JJ cord-285647-9tegcrc3 259 31 diseases disease NNS cord-285647-9tegcrc3 259 32 are be VBP cord-285647-9tegcrc3 259 33 then then RB cord-285647-9tegcrc3 259 34 perturbed perturb VBN cord-285647-9tegcrc3 259 35 . . . cord-285647-9tegcrc3 260 1 For for IN cord-285647-9tegcrc3 260 2 instance instance NN cord-285647-9tegcrc3 260 3 , , , cord-285647-9tegcrc3 260 4 for for IN cord-285647-9tegcrc3 260 5 a a DT cord-285647-9tegcrc3 260 6 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 260 7 process process NN cord-285647-9tegcrc3 260 8 starting start VBG cord-285647-9tegcrc3 260 9 at at IN cord-285647-9tegcrc3 260 10 the the DT cord-285647-9tegcrc3 260 11 protein protein NN cord-285647-9tegcrc3 260 12 ARF6 ARF6 NNP cord-285647-9tegcrc3 260 13 , , , cord-285647-9tegcrc3 260 14 we -PRON- PRP cord-285647-9tegcrc3 260 15 summed sum VBD cord-285647-9tegcrc3 260 16 up up RP cord-285647-9tegcrc3 260 17 the the DT cord-285647-9tegcrc3 260 18 probabilities probability NNS cord-285647-9tegcrc3 260 19 that that IN cord-285647-9tegcrc3 260 20 the the DT cord-285647-9tegcrc3 260 21 38 38 CD cord-285647-9tegcrc3 260 22 proteins protein NNS cord-285647-9tegcrc3 260 23 involved involve VBN cord-285647-9tegcrc3 260 24 in in IN cord-285647-9tegcrc3 260 25 diseases disease NNS cord-285647-9tegcrc3 260 26 are be VBP cord-285647-9tegcrc3 260 27 perturbed perturb VBN cord-285647-9tegcrc3 260 28 at at IN cord-285647-9tegcrc3 260 29 an an DT cord-285647-9tegcrc3 260 30 early early JJ cord-285647-9tegcrc3 260 31 time time NN cord-285647-9tegcrc3 260 32 of of IN cord-285647-9tegcrc3 260 33 the the DT cord-285647-9tegcrc3 260 34 process process NN cord-285647-9tegcrc3 261 1 t t NNP cord-285647-9tegcrc3 261 2 = = SYM cord-285647-9tegcrc3 261 3 0.2 0.2 CD cord-285647-9tegcrc3 261 4 . . . cord-285647-9tegcrc3 262 1 Then then RB cord-285647-9tegcrc3 262 2 , , , cord-285647-9tegcrc3 262 3 we -PRON- PRP cord-285647-9tegcrc3 262 4 obtain obtain VBP cord-285647-9tegcrc3 262 5 a a DT cord-285647-9tegcrc3 262 6 global global JJ cord-285647-9tegcrc3 262 7 perturbation perturbation NN cord-285647-9tegcrc3 262 8 probability probability NN cord-285647-9tegcrc3 262 9 of of IN cord-285647-9tegcrc3 262 10 0.874 0.874 CD cord-285647-9tegcrc3 262 11 . . . cord-285647-9tegcrc3 263 1 By by IN cord-285647-9tegcrc3 263 2 repeating repeat VBG cord-285647-9tegcrc3 263 3 this this DT cord-285647-9tegcrc3 263 4 process process NN cord-285647-9tegcrc3 263 5 for for IN cord-285647-9tegcrc3 263 6 every every DT cord-285647-9tegcrc3 263 7 protein protein NN cord-285647-9tegcrc3 263 8 as as IN cord-285647-9tegcrc3 263 9 an an DT cord-285647-9tegcrc3 263 10 initiator initiator NN cord-285647-9tegcrc3 263 11 , , , cord-285647-9tegcrc3 263 12 we -PRON- PRP cord-285647-9tegcrc3 263 13 obtained obtain VBD cord-285647-9tegcrc3 263 14 the the DT cord-285647-9tegcrc3 263 15 top top JJ cord-285647-9tegcrc3 263 16 disease disease NN cord-285647-9tegcrc3 263 17 activators activator NNS cord-285647-9tegcrc3 263 18 . . . cord-285647-9tegcrc3 264 1 We -PRON- PRP cord-285647-9tegcrc3 264 2 have have VBP cord-285647-9tegcrc3 264 3 found find VBN cord-285647-9tegcrc3 264 4 that that IN cord-285647-9tegcrc3 264 5 none none NN cord-285647-9tegcrc3 264 6 of of IN cord-285647-9tegcrc3 264 7 the the DT cord-285647-9tegcrc3 264 8 20 20 CD cord-285647-9tegcrc3 264 9 top top JJ cord-285647-9tegcrc3 264 10 activators activator NNS cord-285647-9tegcrc3 264 11 is be VBZ cord-285647-9tegcrc3 264 12 involved involve VBN cord-285647-9tegcrc3 264 13 itself -PRON- PRP cord-285647-9tegcrc3 264 14 in in IN cord-285647-9tegcrc3 264 15 any any DT cord-285647-9tegcrc3 264 16 of of IN cord-285647-9tegcrc3 264 17 the the DT cord-285647-9tegcrc3 264 18 human human JJ cord-285647-9tegcrc3 264 19 diseases disease NNS cord-285647-9tegcrc3 264 20 or or CC cord-285647-9tegcrc3 264 21 syndromes syndrome NNS cord-285647-9tegcrc3 264 22 considered consider VBN cord-285647-9tegcrc3 264 23 here here RB cord-285647-9tegcrc3 264 24 . . . cord-285647-9tegcrc3 265 1 They -PRON- PRP cord-285647-9tegcrc3 265 2 are be VBP cord-285647-9tegcrc3 265 3 , , , cord-285647-9tegcrc3 265 4 however however RB cord-285647-9tegcrc3 265 5 , , , cord-285647-9tegcrc3 265 6 proteins protein NNS cord-285647-9tegcrc3 265 7 that that WDT cord-285647-9tegcrc3 265 8 are be VBP cord-285647-9tegcrc3 265 9 important important JJ cord-285647-9tegcrc3 265 10 not not RB cord-285647-9tegcrc3 265 11 because because IN cord-285647-9tegcrc3 265 12 of of IN cord-285647-9tegcrc3 265 13 their -PRON- PRP$ cord-285647-9tegcrc3 265 14 direct direct JJ cord-285647-9tegcrc3 265 15 involvement involvement NN cord-285647-9tegcrc3 265 16 in in IN cord-285647-9tegcrc3 265 17 diseases disease NNS cord-285647-9tegcrc3 265 18 or or CC cord-285647-9tegcrc3 265 19 syndromes syndrome NNS cord-285647-9tegcrc3 265 20 but but CC cord-285647-9tegcrc3 265 21 because because IN cord-285647-9tegcrc3 265 22 they -PRON- PRP cord-285647-9tegcrc3 265 23 propagate propagate VBP cord-285647-9tegcrc3 265 24 perturbations perturbation NNS cord-285647-9tegcrc3 265 25 in in IN cord-285647-9tegcrc3 265 26 a a DT cord-285647-9tegcrc3 265 27 very very RB cord-285647-9tegcrc3 265 28 effective effective JJ cord-285647-9tegcrc3 265 29 way way NN cord-285647-9tegcrc3 265 30 to to IN cord-285647-9tegcrc3 265 31 those those DT cord-285647-9tegcrc3 265 32 directly directly RB cord-285647-9tegcrc3 265 33 involved involve VBN cord-285647-9tegcrc3 265 34 in in IN cord-285647-9tegcrc3 265 35 such such JJ cord-285647-9tegcrc3 265 36 diseases disease NNS cord-285647-9tegcrc3 265 37 / / SYM cord-285647-9tegcrc3 265 38 syndromes syndrome NNS cord-285647-9tegcrc3 265 39 . . . cord-285647-9tegcrc3 266 1 Among among IN cord-285647-9tegcrc3 266 2 the the DT cord-285647-9tegcrc3 266 3 top top JJ cord-285647-9tegcrc3 266 4 activators activator NNS cord-285647-9tegcrc3 266 5 , , , cord-285647-9tegcrc3 266 6 we -PRON- PRP cord-285647-9tegcrc3 266 7 have have VBP cord-285647-9tegcrc3 266 8 found find VBN cord-285647-9tegcrc3 266 9 ARF6 ARF6 NNP cord-285647-9tegcrc3 266 10 , , , cord-285647-9tegcrc3 266 11 ECSIT ECSIT NNP cord-285647-9tegcrc3 266 12 , , , cord-285647-9tegcrc3 266 13 RETREG3 RETREG3 NNS cord-285647-9tegcrc3 266 14 , , , cord-285647-9tegcrc3 266 15 STOM STOM NNP cord-285647-9tegcrc3 266 16 , , , cord-285647-9tegcrc3 266 17 HDAC2 hdac2 NN cord-285647-9tegcrc3 266 18 , , , cord-285647-9tegcrc3 266 19 EXOSC5 exosc5 NN cord-285647-9tegcrc3 266 20 , , , cord-285647-9tegcrc3 266 21 THTPA THTPA NNP cord-285647-9tegcrc3 266 22 , , , cord-285647-9tegcrc3 266 23 among among IN cord-285647-9tegcrc3 266 24 others other NNS cord-285647-9tegcrc3 266 25 shown show VBN cord-285647-9tegcrc3 266 26 in in IN cord-285647-9tegcrc3 266 27 Fig Fig NNP cord-285647-9tegcrc3 266 28 . . . cord-285647-9tegcrc3 267 1 3 3 LS cord-285647-9tegcrc3 267 2 , , , cord-285647-9tegcrc3 267 3 where where WRB cord-285647-9tegcrc3 267 4 we -PRON- PRP cord-285647-9tegcrc3 267 5 illustrate illustrate VBP cord-285647-9tegcrc3 267 6 the the DT cord-285647-9tegcrc3 267 7 PPI PPI NNP cord-285647-9tegcrc3 267 8 network network NN cord-285647-9tegcrc3 267 9 of of IN cord-285647-9tegcrc3 267 10 the the DT cord-285647-9tegcrc3 267 11 proteins protein NNS cord-285647-9tegcrc3 267 12 targeted target VBN cord-285647-9tegcrc3 267 13 by by IN cord-285647-9tegcrc3 267 14 SARS SARS NNP cord-285647-9tegcrc3 267 15 - - HYPH cord-285647-9tegcrc3 267 16 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 268 1 remarking remark VBG cord-285647-9tegcrc3 268 2 the the DT cord-285647-9tegcrc3 268 3 top top JJ cord-285647-9tegcrc3 268 4 20 20 CD cord-285647-9tegcrc3 268 5 disease disease NN cord-285647-9tegcrc3 268 6 activators activator NNS cord-285647-9tegcrc3 268 7 . . . cord-285647-9tegcrc3 268 8 _SP cord-285647-9tegcrc3 269 1 We -PRON- PRP cord-285647-9tegcrc3 269 2 now now RB cord-285647-9tegcrc3 269 3 consider consider VBP cord-285647-9tegcrc3 269 4 how how WRB cord-285647-9tegcrc3 269 5 a a DT cord-285647-9tegcrc3 269 6 perturbation perturbation NN cord-285647-9tegcrc3 269 7 produced produce VBN cord-285647-9tegcrc3 269 8 by by IN cord-285647-9tegcrc3 269 9 SARS SARS NNP cord-285647-9tegcrc3 269 10 - - HYPH cord-285647-9tegcrc3 269 11 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 269 12 on on IN cord-285647-9tegcrc3 269 13 a a DT cord-285647-9tegcrc3 269 14 protein protein NN cord-285647-9tegcrc3 269 15 mainly mainly RB cord-285647-9tegcrc3 269 16 expressed express VBN cord-285647-9tegcrc3 269 17 in in IN cord-285647-9tegcrc3 269 18 the the DT cord-285647-9tegcrc3 269 19 lungs lung NNS cord-285647-9tegcrc3 269 20 can can MD cord-285647-9tegcrc3 269 21 be be VB cord-285647-9tegcrc3 269 22 propagated propagate VBN cord-285647-9tegcrc3 269 23 to to IN cord-285647-9tegcrc3 269 24 proteins protein NNS cord-285647-9tegcrc3 269 25 mainly mainly RB cord-285647-9tegcrc3 269 26 located locate VBN cord-285647-9tegcrc3 269 27 in in IN cord-285647-9tegcrc3 269 28 other other JJ cord-285647-9tegcrc3 269 29 tissues tissue NNS cord-285647-9tegcrc3 269 30 ( ( -LRB- cord-285647-9tegcrc3 269 31 see see VB cord-285647-9tegcrc3 269 32 Table Table NNP cord-285647-9tegcrc3 269 33 S4 S4 NNP cord-285647-9tegcrc3 269 34 in in IN cord-285647-9tegcrc3 269 35 the the DT cord-285647-9tegcrc3 269 36 supplementary supplementary JJ cord-285647-9tegcrc3 269 37 material material NN cord-285647-9tegcrc3 269 38 ) ) -RRB- cord-285647-9tegcrc3 269 39 by by IN cord-285647-9tegcrc3 269 40 a a DT cord-285647-9tegcrc3 269 41 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 269 42 process process NN cord-285647-9tegcrc3 269 43 . . . cord-285647-9tegcrc3 270 1 That that RB cord-285647-9tegcrc3 270 2 is is RB cord-285647-9tegcrc3 270 3 , , , cord-285647-9tegcrc3 270 4 we -PRON- PRP cord-285647-9tegcrc3 270 5 start start VBP cord-285647-9tegcrc3 270 6 the the DT cord-285647-9tegcrc3 270 7 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 270 8 process process NN cord-285647-9tegcrc3 270 9 by by IN cord-285647-9tegcrc3 270 10 perturbing perturb VBG cord-285647-9tegcrc3 270 11 a a DT cord-285647-9tegcrc3 270 12 given give VBN cord-285647-9tegcrc3 270 13 protein protein NN cord-285647-9tegcrc3 270 14 , , , cord-285647-9tegcrc3 270 15 which which WDT cord-285647-9tegcrc3 270 16 is be VBZ cord-285647-9tegcrc3 270 17 mainly mainly RB cord-285647-9tegcrc3 270 18 expressed express VBN cord-285647-9tegcrc3 270 19 in in IN cord-285647-9tegcrc3 270 20 the the DT cord-285647-9tegcrc3 270 21 lungs lung NNS cord-285647-9tegcrc3 270 22 . . . cord-285647-9tegcrc3 271 1 Then then RB cord-285647-9tegcrc3 271 2 , , , cord-285647-9tegcrc3 271 3 we -PRON- PRP cord-285647-9tegcrc3 271 4 observe observe VBP cord-285647-9tegcrc3 271 5 the the DT cord-285647-9tegcrc3 271 6 evolution evolution NN cord-285647-9tegcrc3 271 7 of of IN cord-285647-9tegcrc3 271 8 the the DT cord-285647-9tegcrc3 271 9 perturbation perturbation NN cord-285647-9tegcrc3 271 10 at at IN cord-285647-9tegcrc3 271 11 every every DT cord-285647-9tegcrc3 271 12 one one CD cord-285647-9tegcrc3 271 13 of of IN cord-285647-9tegcrc3 271 14 the the DT cord-285647-9tegcrc3 271 15 proteins protein NNS cord-285647-9tegcrc3 271 16 mainly mainly RB cord-285647-9tegcrc3 271 17 expressed express VBN cord-285647-9tegcrc3 271 18 in in IN cord-285647-9tegcrc3 271 19 other other JJ cord-285647-9tegcrc3 271 20 tissues tissue NNS cord-285647-9tegcrc3 271 21 . . . cord-285647-9tegcrc3 272 1 We -PRON- PRP cord-285647-9tegcrc3 272 2 repeat repeat VBP cord-285647-9tegcrc3 272 3 this this DT cord-285647-9tegcrc3 272 4 process process NN cord-285647-9tegcrc3 272 5 for for IN cord-285647-9tegcrc3 272 6 all all PDT cord-285647-9tegcrc3 272 7 the the DT cord-285647-9tegcrc3 272 8 193 193 CD cord-285647-9tegcrc3 272 9 proteins protein NNS cord-285647-9tegcrc3 272 10 mainly mainly RB cord-285647-9tegcrc3 272 11 expressed express VBN cord-285647-9tegcrc3 272 12 in in IN cord-285647-9tegcrc3 272 13 the the DT cord-285647-9tegcrc3 272 14 lungs lung NNS cord-285647-9tegcrc3 272 15 . . . cord-285647-9tegcrc3 273 1 In in IN cord-285647-9tegcrc3 273 2 every every DT cord-285647-9tegcrc3 273 3 case case NN cord-285647-9tegcrc3 273 4 , , , cord-285647-9tegcrc3 273 5 we -PRON- PRP cord-285647-9tegcrc3 273 6 record record VBP cord-285647-9tegcrc3 273 7 those those DT cord-285647-9tegcrc3 273 8 proteins protein NNS cord-285647-9tegcrc3 273 9 outside outside IN cord-285647-9tegcrc3 273 10 the the DT cord-285647-9tegcrc3 273 11 lungs lung NNS cord-285647-9tegcrc3 273 12 , , , cord-285647-9tegcrc3 273 13 which which WDT cord-285647-9tegcrc3 273 14 are be VBP cord-285647-9tegcrc3 273 15 perturbed perturb VBN cord-285647-9tegcrc3 273 16 at at IN cord-285647-9tegcrc3 273 17 very very RB cord-285647-9tegcrc3 273 18 early early JJ cord-285647-9tegcrc3 273 19 times time NNS cord-285647-9tegcrc3 273 20 of of IN cord-285647-9tegcrc3 273 21 the the DT cord-285647-9tegcrc3 273 22 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 273 23 process process NN cord-285647-9tegcrc3 273 24 . . . cord-285647-9tegcrc3 274 1 For for IN cord-285647-9tegcrc3 274 2 instance instance NN cord-285647-9tegcrc3 274 3 , , , cord-285647-9tegcrc3 274 4 in in IN cord-285647-9tegcrc3 274 5 Fig Fig NNP cord-285647-9tegcrc3 274 6 . . . cord-285647-9tegcrc3 275 1 4 4 LS cord-285647-9tegcrc3 275 2 , , , cord-285647-9tegcrc3 275 3 we -PRON- PRP cord-285647-9tegcrc3 275 4 illustrate illustrate VBP cord-285647-9tegcrc3 275 5 one one CD cord-285647-9tegcrc3 275 6 example example NN cord-285647-9tegcrc3 275 7 in in IN cord-285647-9tegcrc3 275 8 which which WDT cord-285647-9tegcrc3 275 9 the the DT cord-285647-9tegcrc3 275 10 initiator initiator NN cord-285647-9tegcrc3 275 11 is be VBZ cord-285647-9tegcrc3 275 12 the the DT cord-285647-9tegcrc3 275 13 protein protein NN cord-285647-9tegcrc3 275 14 GOLGA2 golga2 NN cord-285647-9tegcrc3 275 15 , , , cord-285647-9tegcrc3 275 16 which which WDT cord-285647-9tegcrc3 275 17 triggers trigger VBZ cord-285647-9tegcrc3 275 18 a a DT cord-285647-9tegcrc3 275 19 shock shock NN cord-285647-9tegcrc3 275 20 wave wave NN cord-285647-9tegcrc3 275 21 on on IN cord-285647-9tegcrc3 275 22 proteins protein NNS cord-285647-9tegcrc3 275 23 RBM41 RBM41 NNP cord-285647-9tegcrc3 275 24 , , , cord-285647-9tegcrc3 275 25 TL5 TL5 NNP cord-285647-9tegcrc3 275 26 , , , cord-285647-9tegcrc3 275 27 and and CC cord-285647-9tegcrc3 275 28 PKP2 PKP2 NNP cord-285647-9tegcrc3 275 29 , , , cord-285647-9tegcrc3 275 30 which which WDT cord-285647-9tegcrc3 275 31 are be VBP cord-285647-9tegcrc3 275 32 expressed express VBN cord-285647-9tegcrc3 275 33 mainly mainly RB cord-285647-9tegcrc3 275 34 outside outside IN cord-285647-9tegcrc3 275 35 the the DT cord-285647-9tegcrc3 275 36 lungs lung NNS cord-285647-9tegcrc3 275 37 . . . cord-285647-9tegcrc3 276 1 We -PRON- PRP cord-285647-9tegcrc3 276 2 consider consider VBP cord-285647-9tegcrc3 276 3 such such JJ cord-285647-9tegcrc3 276 4 perturbations perturbation NNS cord-285647-9tegcrc3 276 5 only only RB cord-285647-9tegcrc3 276 6 if if IN cord-285647-9tegcrc3 276 7 they -PRON- PRP cord-285647-9tegcrc3 276 8 occur occur VBP cord-285647-9tegcrc3 276 9 at at IN cord-285647-9tegcrc3 276 10 t t NN cord-285647-9tegcrc3 276 11 < < XX cord-285647-9tegcrc3 276 12 1 1 CD cord-285647-9tegcrc3 276 13 . . . cord-285647-9tegcrc3 277 1 Not not RB cord-285647-9tegcrc3 277 2 every every DT cord-285647-9tegcrc3 277 3 one one CD cord-285647-9tegcrc3 277 4 of of IN cord-285647-9tegcrc3 277 5 the the DT cord-285647-9tegcrc3 277 6 proteins protein NNS cord-285647-9tegcrc3 277 7 expressed express VBN cord-285647-9tegcrc3 277 8 outside outside IN cord-285647-9tegcrc3 277 9 the the DT cord-285647-9tegcrc3 277 10 lungs lung NNS cord-285647-9tegcrc3 277 11 is be VBZ cord-285647-9tegcrc3 277 12 triggered trigger VBN cord-285647-9tegcrc3 277 13 by by IN cord-285647-9tegcrc3 277 14 such such JJ cord-285647-9tegcrc3 277 15 shock shock NN cord-285647-9tegcrc3 277 16 waves wave NNS cord-285647-9tegcrc3 277 17 at at IN cord-285647-9tegcrc3 277 18 a a DT cord-285647-9tegcrc3 277 19 very very RB cord-285647-9tegcrc3 277 20 early early JJ cord-285647-9tegcrc3 277 21 time time NN cord-285647-9tegcrc3 277 22 of of IN cord-285647-9tegcrc3 277 23 the the DT cord-285647-9tegcrc3 277 24 diffusion diffusion NN cord-285647-9tegcrc3 277 25 . . . cord-285647-9tegcrc3 278 1 For for IN cord-285647-9tegcrc3 278 2 instance instance NN cord-285647-9tegcrc3 278 3 , , , cord-285647-9tegcrc3 278 4 proteins protein NNS cord-285647-9tegcrc3 278 5 MARK1 MARK1 NNP cord-285647-9tegcrc3 279 1 and and CC cord-285647-9tegcrc3 279 2 SLC27A2 SLC27A2 NNS cord-285647-9tegcrc3 279 3 are be VBP cord-285647-9tegcrc3 279 4 perturbed perturb VBN cord-285647-9tegcrc3 279 5 in in IN cord-285647-9tegcrc3 279 6 very very RB cord-285647-9tegcrc3 279 7 slow slow JJ cord-285647-9tegcrc3 279 8 processes process NNS cord-285647-9tegcrc3 279 9 and and CC cord-285647-9tegcrc3 279 10 do do VBP cord-285647-9tegcrc3 279 11 not not RB cord-285647-9tegcrc3 279 12 produce produce VB cord-285647-9tegcrc3 279 13 the the DT cord-285647-9tegcrc3 279 14 characteristic characteristic JJ cord-285647-9tegcrc3 279 15 high high JJ cord-285647-9tegcrc3 279 16 peaks peak NNS cord-285647-9tegcrc3 279 17 in in IN cord-285647-9tegcrc3 279 18 the the DT cord-285647-9tegcrc3 279 19 probability probability NN cord-285647-9tegcrc3 279 20 at at IN cord-285647-9tegcrc3 279 21 very very RB cord-285647-9tegcrc3 279 22 short short JJ cord-285647-9tegcrc3 279 23 times time NNS cord-285647-9tegcrc3 279 24 . . . cord-285647-9tegcrc3 280 1 On on IN cord-285647-9tegcrc3 280 2 the the DT cord-285647-9tegcrc3 280 3 other other JJ cord-285647-9tegcrc3 280 4 hand hand NN cord-285647-9tegcrc3 280 5 , , , cord-285647-9tegcrc3 280 6 there there EX cord-285647-9tegcrc3 280 7 are be VBP cord-285647-9tegcrc3 280 8 proteins protein NNS cord-285647-9tegcrc3 280 9 expressed express VBN cord-285647-9tegcrc3 280 10 outside outside IN cord-285647-9tegcrc3 280 11 the the DT cord-285647-9tegcrc3 280 12 lungs lung NNS cord-285647-9tegcrc3 280 13 that that WDT cord-285647-9tegcrc3 280 14 are be VBP cord-285647-9tegcrc3 280 15 triggered trigger VBN cord-285647-9tegcrc3 280 16 by by IN cord-285647-9tegcrc3 280 17 more more JJR cord-285647-9tegcrc3 280 18 than than IN cord-285647-9tegcrc3 280 19 one one CD cord-285647-9tegcrc3 280 20 protein protein NN cord-285647-9tegcrc3 280 21 from from IN cord-285647-9tegcrc3 280 22 the the DT cord-285647-9tegcrc3 280 23 lungs lung NNS cord-285647-9tegcrc3 280 24 . . . cord-285647-9tegcrc3 281 1 The the DT cord-285647-9tegcrc3 281 2 case case NN cord-285647-9tegcrc3 281 3 of of IN cord-285647-9tegcrc3 281 4 GOLGA2 golga2 NN cord-285647-9tegcrc3 281 5 is be VBZ cord-285647-9tegcrc3 281 6 an an DT cord-285647-9tegcrc3 281 7 example example NN cord-285647-9tegcrc3 281 8 of of IN cord-285647-9tegcrc3 281 9 a a DT cord-285647-9tegcrc3 281 10 protein protein NN cord-285647-9tegcrc3 281 11 triggered trigger VBN cord-285647-9tegcrc3 281 12 by by IN cord-285647-9tegcrc3 281 13 three three CD cord-285647-9tegcrc3 281 14 proteins protein NNS cord-285647-9tegcrc3 281 15 in in IN cord-285647-9tegcrc3 281 16 the the DT cord-285647-9tegcrc3 281 17 lungs lung NNS cord-285647-9tegcrc3 281 18 . . . cord-285647-9tegcrc3 282 1 In in IN cord-285647-9tegcrc3 282 2 Table table NN cord-285647-9tegcrc3 282 3 I -PRON- PRP cord-285647-9tegcrc3 282 4 , , , cord-285647-9tegcrc3 282 5 we -PRON- PRP cord-285647-9tegcrc3 282 6 list list VBP cord-285647-9tegcrc3 282 7 some some DT cord-285647-9tegcrc3 282 8 of of IN cord-285647-9tegcrc3 282 9 the the DT cord-285647-9tegcrc3 282 10 proteins protein NNS cord-285647-9tegcrc3 282 11 expressed express VBN cord-285647-9tegcrc3 282 12 mainly mainly RB cord-285647-9tegcrc3 282 13 in in IN cord-285647-9tegcrc3 282 14 tissues tissue NNS cord-285647-9tegcrc3 282 15 outside outside IN cord-285647-9tegcrc3 282 16 the the DT cord-285647-9tegcrc3 282 17 lungs lung NNS cord-285647-9tegcrc3 282 18 , , , cord-285647-9tegcrc3 282 19 which which WDT cord-285647-9tegcrc3 282 20 are be VBP cord-285647-9tegcrc3 282 21 heavily heavily RB cord-285647-9tegcrc3 282 22 perturbed perturb VBN cord-285647-9tegcrc3 282 23 by by IN cord-285647-9tegcrc3 282 24 proteins protein NNS cord-285647-9tegcrc3 282 25 in in IN cord-285647-9tegcrc3 282 26 the the DT cord-285647-9tegcrc3 282 27 lungs lung NNS cord-285647-9tegcrc3 282 28 . . . cord-285647-9tegcrc3 283 1 The the DT cord-285647-9tegcrc3 283 2 TABLE table NN cord-285647-9tegcrc3 283 3 I. I. NNP cord-285647-9tegcrc3 283 4 Multi multi JJ cord-285647-9tegcrc3 283 5 - - JJ cord-285647-9tegcrc3 283 6 organ organ JJ cord-285647-9tegcrc3 283 7 propagation propagation NN cord-285647-9tegcrc3 283 8 of of IN cord-285647-9tegcrc3 283 9 perturbations perturbation NNS cord-285647-9tegcrc3 283 10 . . . cord-285647-9tegcrc3 284 1 Proteins protein NNS cord-285647-9tegcrc3 284 2 mainly mainly RB cord-285647-9tegcrc3 284 3 expressed express VBD cord-285647-9tegcrc3 284 4 outside outside IN cord-285647-9tegcrc3 284 5 the the DT cord-285647-9tegcrc3 284 6 lungs lung NNS cord-285647-9tegcrc3 284 7 are be VBP cord-285647-9tegcrc3 284 8 significantly significantly RB cord-285647-9tegcrc3 284 9 perturbed perturb VBN cord-285647-9tegcrc3 284 10 during during IN cord-285647-9tegcrc3 284 11 diffusive diffusive JJ cord-285647-9tegcrc3 284 12 processes process NNS cord-285647-9tegcrc3 284 13 that that WDT cord-285647-9tegcrc3 284 14 have have VBP cord-285647-9tegcrc3 284 15 started start VBN cord-285647-9tegcrc3 284 16 at at IN cord-285647-9tegcrc3 284 17 other other JJ cord-285647-9tegcrc3 284 18 proteins protein NNS cord-285647-9tegcrc3 284 19 expressed express VBN cord-285647-9tegcrc3 284 20 in in IN cord-285647-9tegcrc3 284 21 the the DT cord-285647-9tegcrc3 284 22 lungs lung NNS cord-285647-9tegcrc3 284 23 . . . cord-285647-9tegcrc3 285 1 Act Act NNP cord-285647-9tegcrc3 285 2 . . . cord-285647-9tegcrc3 286 1 is be VBZ cord-285647-9tegcrc3 286 2 the the DT cord-285647-9tegcrc3 286 3 number number NN cord-285647-9tegcrc3 286 4 of of IN cord-285647-9tegcrc3 286 5 lung lung NN cord-285647-9tegcrc3 286 6 proteins protein NNS cord-285647-9tegcrc3 286 7 activators activator NNS cord-285647-9tegcrc3 286 8 , , , cord-285647-9tegcrc3 286 9 p p NN cord-285647-9tegcrc3 286 10 tot tot NN cord-285647-9tegcrc3 286 11 is be VBZ cord-285647-9tegcrc3 286 12 the the DT cord-285647-9tegcrc3 286 13 sum sum NN cord-285647-9tegcrc3 286 14 of of IN cord-285647-9tegcrc3 286 15 the the DT cord-285647-9tegcrc3 286 16 probabilities probability NNS cord-285647-9tegcrc3 286 17 of of IN cord-285647-9tegcrc3 286 18 finding find VBG cord-285647-9tegcrc3 286 19 the the DT cord-285647-9tegcrc3 286 20 diffusive diffusive JJ cord-285647-9tegcrc3 286 21 particle particle NN cord-285647-9tegcrc3 286 22 at at IN cord-285647-9tegcrc3 286 23 this this DT cord-285647-9tegcrc3 286 24 protein protein NN cord-285647-9tegcrc3 286 25 , , , cord-285647-9tegcrc3 286 26 and and CC cord-285647-9tegcrc3 286 27 t t NN cord-285647-9tegcrc3 286 28 mean mean VB cord-285647-9tegcrc3 286 29 is be VBZ cord-285647-9tegcrc3 286 30 the the DT cord-285647-9tegcrc3 286 31 average average JJ cord-285647-9tegcrc3 286 32 time time NN cord-285647-9tegcrc3 286 33 of of IN cord-285647-9tegcrc3 286 34 activation activation NN cord-285647-9tegcrc3 286 35 ( ( -LRB- cord-285647-9tegcrc3 286 36 see see VB cord-285647-9tegcrc3 286 37 the the DT cord-285647-9tegcrc3 286 38 text text NN cord-285647-9tegcrc3 286 39 for for IN cord-285647-9tegcrc3 286 40 explanations explanation NNS cord-285647-9tegcrc3 286 41 ) ) -RRB- cord-285647-9tegcrc3 286 42 . . . cord-285647-9tegcrc3 287 1 The the DT cord-285647-9tegcrc3 287 2 tissues tissue NNS cord-285647-9tegcrc3 287 3 of of IN cord-285647-9tegcrc3 287 4 main main JJ cord-285647-9tegcrc3 287 5 expression expression NN cord-285647-9tegcrc3 287 6 are be VBP cord-285647-9tegcrc3 287 7 selected select VBN cord-285647-9tegcrc3 287 8 among among IN cord-285647-9tegcrc3 287 9 the the DT cord-285647-9tegcrc3 287 10 ones one NNS cord-285647-9tegcrc3 287 11 with with IN cord-285647-9tegcrc3 287 12 the the DT cord-285647-9tegcrc3 287 13 highest high JJS cord-285647-9tegcrc3 287 14 Consensus Consensus NNP cord-285647-9tegcrc3 287 15 Normalized normalize VBN cord-285647-9tegcrc3 287 16 eXpression eXpression NNP cord-285647-9tegcrc3 287 17 ( ( -LRB- cord-285647-9tegcrc3 287 18 NX NX NNP cord-285647-9tegcrc3 287 19 ) ) -RRB- cord-285647-9tegcrc3 287 20 levels level NNS cord-285647-9tegcrc3 287 21 by by IN cord-285647-9tegcrc3 287 22 combining combine VBG cord-285647-9tegcrc3 287 23 the the DT cord-285647-9tegcrc3 287 24 data datum NNS cord-285647-9tegcrc3 287 25 from from IN cord-285647-9tegcrc3 287 26 the the DT cord-285647-9tegcrc3 287 27 three three CD cord-285647-9tegcrc3 287 28 transcriptomics transcriptomic NNS cord-285647-9tegcrc3 287 29 datasets dataset NNS cord-285647-9tegcrc3 287 30 ( ( -LRB- cord-285647-9tegcrc3 287 31 HPA HPA NNP cord-285647-9tegcrc3 287 32 , , , cord-285647-9tegcrc3 287 33 GTEx gtex NN cord-285647-9tegcrc3 287 34 , , , cord-285647-9tegcrc3 287 35 and and CC cord-285647-9tegcrc3 287 36 FANTOM5 fantom5 LS cord-285647-9tegcrc3 287 37 ) ) -RRB- cord-285647-9tegcrc3 287 38 using use VBG cord-285647-9tegcrc3 287 39 the the DT cord-285647-9tegcrc3 287 40 internal internal JJ cord-285647-9tegcrc3 287 41 normalization normalization NN cord-285647-9tegcrc3 287 42 pipeline pipeline NN cord-285647-9tegcrc3 287 43 . . . cord-285647-9tegcrc3 288 1 49 49 CD cord-285647-9tegcrc3 288 2 Boldface boldface NN cord-285647-9tegcrc3 288 3 denotes denote VBZ cord-285647-9tegcrc3 288 4 the the DT cord-285647-9tegcrc3 288 5 highest high JJS cord-285647-9tegcrc3 288 6 value value NN cord-285647-9tegcrc3 288 7 in in IN cord-285647-9tegcrc3 288 8 each each DT cord-285647-9tegcrc3 288 9 of of IN cord-285647-9tegcrc3 288 10 the the DT cord-285647-9tegcrc3 288 11 columns column NNS cord-285647-9tegcrc3 288 12 . . . cord-285647-9tegcrc3 289 1 Act Act NNP cord-285647-9tegcrc3 289 2 . . . cord-285647-9tegcrc3 290 1 Table table NN cord-285647-9tegcrc3 290 2 S5 S5 NNP cord-285647-9tegcrc3 290 3 of of IN cord-285647-9tegcrc3 290 4 the the DT cord-285647-9tegcrc3 290 5 supplementary supplementary JJ cord-285647-9tegcrc3 290 6 material material NN cord-285647-9tegcrc3 290 7 . . . cord-285647-9tegcrc3 291 1 We -PRON- PRP cord-285647-9tegcrc3 291 2 give give VBP cord-285647-9tegcrc3 291 3 three three CD cord-285647-9tegcrc3 291 4 indicators indicator NNS cord-285647-9tegcrc3 291 5 of of IN cord-285647-9tegcrc3 291 6 the the DT cord-285647-9tegcrc3 291 7 importance importance NN cord-285647-9tegcrc3 291 8 of of IN cord-285647-9tegcrc3 291 9 the the DT cord-285647-9tegcrc3 291 10 perturbation perturbation NN cord-285647-9tegcrc3 291 11 of of IN cord-285647-9tegcrc3 291 12 these these DT cord-285647-9tegcrc3 291 13 proteins protein NNS cord-285647-9tegcrc3 291 14 . . . cord-285647-9tegcrc3 292 1 They -PRON- PRP cord-285647-9tegcrc3 292 2 are be VBP cord-285647-9tegcrc3 292 3 Act Act NNP cord-285647-9tegcrc3 292 4 . . . cord-285647-9tegcrc3 293 1 , , , cord-285647-9tegcrc3 293 2 which which WDT cord-285647-9tegcrc3 293 3 is be VBZ cord-285647-9tegcrc3 293 4 the the DT cord-285647-9tegcrc3 293 5 number number NN cord-285647-9tegcrc3 293 6 of of IN cord-285647-9tegcrc3 293 7 proteins protein NNS cord-285647-9tegcrc3 293 8 in in IN cord-285647-9tegcrc3 293 9 the the DT cord-285647-9tegcrc3 293 10 lungs lung NNS cord-285647-9tegcrc3 293 11 that that WDT cord-285647-9tegcrc3 293 12 activate activate VBP cord-285647-9tegcrc3 293 13 each each DT cord-285647-9tegcrc3 293 14 of of IN cord-285647-9tegcrc3 293 15 them -PRON- PRP cord-285647-9tegcrc3 293 16 ; ; : cord-285647-9tegcrc3 293 17 p p NN cord-285647-9tegcrc3 293 18 tot tot NN cord-285647-9tegcrc3 293 19 , , , cord-285647-9tegcrc3 293 20 which which WDT cord-285647-9tegcrc3 293 21 is be VBZ cord-285647-9tegcrc3 293 22 the the DT cord-285647-9tegcrc3 293 23 sum sum NN cord-285647-9tegcrc3 293 24 of of IN cord-285647-9tegcrc3 293 25 the the DT cord-285647-9tegcrc3 293 26 probabilities probability NNS cord-285647-9tegcrc3 293 27 of of IN cord-285647-9tegcrc3 293 28 finding find VBG cord-285647-9tegcrc3 293 29 the the DT cord-285647-9tegcrc3 293 30 diffusive diffusive JJ cord-285647-9tegcrc3 293 31 particle particle NN cord-285647-9tegcrc3 293 32 at at IN cord-285647-9tegcrc3 293 33 this this DT cord-285647-9tegcrc3 293 34 protein protein NN cord-285647-9tegcrc3 293 35 for for IN cord-285647-9tegcrc3 293 36 diffusive diffusive JJ cord-285647-9tegcrc3 293 37 processes process NNS cord-285647-9tegcrc3 293 38 that that WDT cord-285647-9tegcrc3 293 39 have have VBP cord-285647-9tegcrc3 293 40 started start VBN cord-285647-9tegcrc3 293 41 in in IN cord-285647-9tegcrc3 293 42 their -PRON- PRP$ cord-285647-9tegcrc3 293 43 activators activator NNS cord-285647-9tegcrc3 293 44 ; ; : cord-285647-9tegcrc3 293 45 and and CC cord-285647-9tegcrc3 293 46 t t XX cord-285647-9tegcrc3 293 47 mean mean VB cord-285647-9tegcrc3 293 48 , , , cord-285647-9tegcrc3 293 49 which which WDT cord-285647-9tegcrc3 293 50 is be VBZ cord-285647-9tegcrc3 293 51 the the DT cord-285647-9tegcrc3 293 52 average average JJ cord-285647-9tegcrc3 293 53 time time NN cord-285647-9tegcrc3 293 54 required require VBN cord-285647-9tegcrc3 293 55 by by IN cord-285647-9tegcrc3 293 56 activators activator NNS cord-285647-9tegcrc3 293 57 to to TO cord-285647-9tegcrc3 293 58 perturb perturb VB cord-285647-9tegcrc3 293 59 the the DT cord-285647-9tegcrc3 293 60 corresponding correspond VBG cord-285647-9tegcrc3 293 61 protein protein NN cord-285647-9tegcrc3 293 62 . . . cord-285647-9tegcrc3 294 1 For for IN cord-285647-9tegcrc3 294 2 instance instance NN cord-285647-9tegcrc3 294 3 , , , cord-285647-9tegcrc3 294 4 PKP2 PKP2 NNP cord-285647-9tegcrc3 294 5 is be VBZ cord-285647-9tegcrc3 294 6 perturbed perturb VBN cord-285647-9tegcrc3 294 7 by by IN cord-285647-9tegcrc3 294 8 21 21 CD cord-285647-9tegcrc3 294 9 proteins protein NNS cord-285647-9tegcrc3 294 10 in in IN cord-285647-9tegcrc3 294 11 the the DT cord-285647-9tegcrc3 294 12 lungs lung NNS cord-285647-9tegcrc3 294 13 , , , cord-285647-9tegcrc3 294 14 which which WDT cord-285647-9tegcrc3 294 15 indicates indicate VBZ cord-285647-9tegcrc3 294 16 that that IN cord-285647-9tegcrc3 294 17 this this DT cord-285647-9tegcrc3 294 18 protein protein NN cord-285647-9tegcrc3 294 19 , , , cord-285647-9tegcrc3 294 20 mainly mainly RB cord-285647-9tegcrc3 294 21 expressed express VBN cord-285647-9tegcrc3 294 22 in in IN cord-285647-9tegcrc3 294 23 the the DT cord-285647-9tegcrc3 294 24 heart heart NN cord-285647-9tegcrc3 294 25 muscle muscle NN cord-285647-9tegcrc3 294 26 , , , cord-285647-9tegcrc3 294 27 has have VBZ cord-285647-9tegcrc3 294 28 a a DT cord-285647-9tegcrc3 294 29 large large JJ cord-285647-9tegcrc3 294 30 chance chance NN cord-285647-9tegcrc3 294 31 of of IN cord-285647-9tegcrc3 294 32 being be VBG cord-285647-9tegcrc3 294 33 perturbed perturb VBN cord-285647-9tegcrc3 294 34 by by IN cord-285647-9tegcrc3 294 35 diffusive diffusive JJ cord-285647-9tegcrc3 294 36 processes process NNS cord-285647-9tegcrc3 294 37 starting start VBG cord-285647-9tegcrc3 294 38 in in IN cord-285647-9tegcrc3 294 39 proteins protein NNS cord-285647-9tegcrc3 294 40 mainly mainly RB cord-285647-9tegcrc3 294 41 located locate VBN cord-285647-9tegcrc3 294 42 at at IN cord-285647-9tegcrc3 294 43 the the DT cord-285647-9tegcrc3 294 44 lungs lung NNS cord-285647-9tegcrc3 294 45 . . . cord-285647-9tegcrc3 295 1 Protein Protein NNP cord-285647-9tegcrc3 295 2 PRIM2 PRIM2 NNP cord-285647-9tegcrc3 295 3 is be VBZ cord-285647-9tegcrc3 295 4 activated activate VBN cord-285647-9tegcrc3 295 5 by by IN cord-285647-9tegcrc3 295 6 5 5 CD cord-285647-9tegcrc3 295 7 proteins protein NNS cord-285647-9tegcrc3 295 8 in in IN cord-285647-9tegcrc3 295 9 the the DT cord-285647-9tegcrc3 295 10 lungs lung NNS cord-285647-9tegcrc3 295 11 , , , cord-285647-9tegcrc3 295 12 but but CC cord-285647-9tegcrc3 295 13 if if IN cord-285647-9tegcrc3 295 14 all all PDT cord-285647-9tegcrc3 295 15 these these DT cord-285647-9tegcrc3 295 16 proteins protein NNS cord-285647-9tegcrc3 295 17 were be VBD cord-285647-9tegcrc3 295 18 acting act VBG cord-285647-9tegcrc3 295 19 at at IN cord-285647-9tegcrc3 295 20 the the DT cord-285647-9tegcrc3 295 21 same same JJ cord-285647-9tegcrc3 295 22 time time NN cord-285647-9tegcrc3 295 23 , , , cord-285647-9tegcrc3 295 24 the the DT cord-285647-9tegcrc3 295 25 probability probability NN cord-285647-9tegcrc3 295 26 that that WDT cord-285647-9tegcrc3 295 27 PRIM2 PRIM2 NNP cord-285647-9tegcrc3 295 28 is be VBZ cord-285647-9tegcrc3 295 29 perturbed perturb VBN cord-285647-9tegcrc3 295 30 will will MD cord-285647-9tegcrc3 295 31 be be VB cord-285647-9tegcrc3 295 32 very very RB cord-285647-9tegcrc3 295 33 high high JJ cord-285647-9tegcrc3 295 34 , , , cord-285647-9tegcrc3 295 35 p p NN cord-285647-9tegcrc3 295 36 tot tot NN cord-285647-9tegcrc3 295 37 ≈ ≈ NNP cord-285647-9tegcrc3 295 38 0.536 0.536 CD cord-285647-9tegcrc3 295 39 . . . cord-285647-9tegcrc3 296 1 Finally finally RB cord-285647-9tegcrc3 296 2 , , , cord-285647-9tegcrc3 296 3 protein protein NN cord-285647-9tegcrc3 296 4 TLE5 TLE5 NNP cord-285647-9tegcrc3 296 5 is be VBZ cord-285647-9tegcrc3 296 6 perturbed perturb VBN cord-285647-9tegcrc3 296 7 by by IN cord-285647-9tegcrc3 296 8 13 13 CD cord-285647-9tegcrc3 296 9 proteins protein NNS cord-285647-9tegcrc3 296 10 in in IN cord-285647-9tegcrc3 296 11 the the DT cord-285647-9tegcrc3 296 12 lungs lung NNS cord-285647-9tegcrc3 296 13 , , , cord-285647-9tegcrc3 296 14 which which WDT cord-285647-9tegcrc3 296 15 needs need VBZ cord-285647-9tegcrc3 296 16 as as IN cord-285647-9tegcrc3 296 17 an an DT cord-285647-9tegcrc3 296 18 average average JJ cord-285647-9tegcrc3 296 19 t t NN cord-285647-9tegcrc3 296 20 mean mean VB cord-285647-9tegcrc3 296 21 ≈ ≈ NNP cord-285647-9tegcrc3 296 22 0.24 0.24 CD cord-285647-9tegcrc3 296 23 to to TO cord-285647-9tegcrc3 296 24 perturb perturb VB cord-285647-9tegcrc3 296 25 TLE5 TLE5 NNP cord-285647-9tegcrc3 296 26 . . . cord-285647-9tegcrc3 297 1 These these DT cord-285647-9tegcrc3 297 2 proteins protein NNS cord-285647-9tegcrc3 297 3 do do VBP cord-285647-9tegcrc3 297 4 not not RB cord-285647-9tegcrc3 297 5 form form VB cord-285647-9tegcrc3 297 6 a a DT cord-285647-9tegcrc3 297 7 connected connected JJ cord-285647-9tegcrc3 297 8 component component NN cord-285647-9tegcrc3 297 9 among among IN cord-285647-9tegcrc3 297 10 them -PRON- PRP cord-285647-9tegcrc3 297 11 in in IN cord-285647-9tegcrc3 297 12 the the DT cord-285647-9tegcrc3 297 13 network network NN cord-285647-9tegcrc3 297 14 . . . cord-285647-9tegcrc3 298 1 The the DT cord-285647-9tegcrc3 298 2 average average JJ cord-285647-9tegcrc3 298 3 shortest short JJS cord-285647-9tegcrc3 298 4 diffusion diffusion NN cord-285647-9tegcrc3 298 5 path path NN cord-285647-9tegcrc3 298 6 between between IN cord-285647-9tegcrc3 298 7 them -PRON- PRP cord-285647-9tegcrc3 298 8 is be VBZ cord-285647-9tegcrc3 298 9 5.286 5.286 CD cord-285647-9tegcrc3 298 10 with with IN cord-285647-9tegcrc3 298 11 a a DT cord-285647-9tegcrc3 298 12 maximum maximum JJ cord-285647-9tegcrc3 298 13 shortest short JJS cord-285647-9tegcrc3 298 14 subdiffusion subdiffusion NN cord-285647-9tegcrc3 298 15 path path NN cord-285647-9tegcrc3 298 16 of of IN cord-285647-9tegcrc3 298 17 10 10 CD cord-285647-9tegcrc3 298 18 . . . cord-285647-9tegcrc3 299 1 As as IN cord-285647-9tegcrc3 299 2 an an DT cord-285647-9tegcrc3 299 3 average average NN cord-285647-9tegcrc3 299 4 , , , cord-285647-9tegcrc3 299 5 they -PRON- PRP cord-285647-9tegcrc3 299 6 are be VBP cord-285647-9tegcrc3 299 7 almost almost RB cord-285647-9tegcrc3 299 8 equidistant equidistant JJ cord-285647-9tegcrc3 299 9 from from IN cord-285647-9tegcrc3 299 10 the the DT cord-285647-9tegcrc3 299 11 rest rest NN cord-285647-9tegcrc3 299 12 of of IN cord-285647-9tegcrc3 299 13 the the DT cord-285647-9tegcrc3 299 14 proteins protein NNS cord-285647-9tegcrc3 299 15 in in IN cord-285647-9tegcrc3 299 16 the the DT cord-285647-9tegcrc3 299 17 network network NN cord-285647-9tegcrc3 299 18 as as IN cord-285647-9tegcrc3 299 19 among among IN cord-285647-9tegcrc3 299 20 themselves -PRON- PRP cord-285647-9tegcrc3 299 21 . . . cord-285647-9tegcrc3 300 1 That that RB cord-285647-9tegcrc3 300 2 is is RB cord-285647-9tegcrc3 300 3 , , , cord-285647-9tegcrc3 300 4 the the DT cord-285647-9tegcrc3 300 5 average average JJ cord-285647-9tegcrc3 300 6 shortest short JJS cord-285647-9tegcrc3 300 7 subdiffusion subdiffusion NN cord-285647-9tegcrc3 300 8 path path NN cord-285647-9tegcrc3 300 9 between between IN cord-285647-9tegcrc3 300 10 these these DT cord-285647-9tegcrc3 300 11 proteins protein NNS cord-285647-9tegcrc3 300 12 expressed express VBN cord-285647-9tegcrc3 300 13 outside outside IN cord-285647-9tegcrc3 300 14 the the DT cord-285647-9tegcrc3 300 15 lungs lung NNS cord-285647-9tegcrc3 300 16 and and CC cord-285647-9tegcrc3 300 17 the the DT cord-285647-9tegcrc3 300 18 rest rest NN cord-285647-9tegcrc3 300 19 of of IN cord-285647-9tegcrc3 300 20 the the DT cord-285647-9tegcrc3 300 21 proteins protein NNS cord-285647-9tegcrc3 300 22 in in IN cord-285647-9tegcrc3 300 23 the the DT cord-285647-9tegcrc3 300 24 network network NN cord-285647-9tegcrc3 300 25 is be VBZ cord-285647-9tegcrc3 300 26 5.106 5.106 CD cord-285647-9tegcrc3 300 27 . . . cord-285647-9tegcrc3 301 1 Therefore therefore RB cord-285647-9tegcrc3 301 2 , , , cord-285647-9tegcrc3 301 3 these these DT cord-285647-9tegcrc3 301 4 proteins protein NNS cord-285647-9tegcrc3 301 5 can can MD cord-285647-9tegcrc3 301 6 be be VB cord-285647-9tegcrc3 301 7 reached reach VBN cord-285647-9tegcrc3 301 8 from from IN cord-285647-9tegcrc3 301 9 other other JJ cord-285647-9tegcrc3 301 10 proteins protein NNS cord-285647-9tegcrc3 301 11 outside outside IN cord-285647-9tegcrc3 301 12 the the DT cord-285647-9tegcrc3 301 13 lungs lung NNS cord-285647-9tegcrc3 301 14 in in IN cord-285647-9tegcrc3 301 15 no no DT cord-285647-9tegcrc3 301 16 more more JJR cord-285647-9tegcrc3 301 17 than than IN cord-285647-9tegcrc3 301 18 six six CD cord-285647-9tegcrc3 301 19 steps step NNS cord-285647-9tegcrc3 301 20 in in IN cord-285647-9tegcrc3 301 21 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 301 22 processes process NNS cord-285647-9tegcrc3 301 23 like like IN cord-285647-9tegcrc3 301 24 the the DT cord-285647-9tegcrc3 301 25 ones one NNS cord-285647-9tegcrc3 301 26 considered consider VBN cord-285647-9tegcrc3 301 27 here here RB cord-285647-9tegcrc3 301 28 . . . cord-285647-9tegcrc3 302 1 Finally finally RB cord-285647-9tegcrc3 302 2 , , , cord-285647-9tegcrc3 302 3 we -PRON- PRP cord-285647-9tegcrc3 302 4 study study VBP cord-285647-9tegcrc3 302 5 here here RB cord-285647-9tegcrc3 302 6 how how WRB cord-285647-9tegcrc3 302 7 the the DT cord-285647-9tegcrc3 302 8 diffusive diffusive JJ cord-285647-9tegcrc3 302 9 process process NN cord-285647-9tegcrc3 302 10 determines determine VBZ cord-285647-9tegcrc3 302 11 the the DT cord-285647-9tegcrc3 302 12 paths path NNS cord-285647-9tegcrc3 302 13 that that WDT cord-285647-9tegcrc3 302 14 the the DT cord-285647-9tegcrc3 302 15 perturbation perturbation NN cord-285647-9tegcrc3 302 16 follows follow VBZ cord-285647-9tegcrc3 302 17 when when WRB cord-285647-9tegcrc3 302 18 diffusing diffuse VBG cord-285647-9tegcrc3 302 19 from from IN cord-285647-9tegcrc3 302 20 a a DT cord-285647-9tegcrc3 302 21 protein protein NN cord-285647-9tegcrc3 302 22 to to IN cord-285647-9tegcrc3 302 23 another another DT cord-285647-9tegcrc3 302 24 not not RB cord-285647-9tegcrc3 302 25 directly directly RB cord-285647-9tegcrc3 302 26 connected connect VBN cord-285647-9tegcrc3 302 27 to to IN cord-285647-9tegcrc3 302 28 it -PRON- PRP cord-285647-9tegcrc3 302 29 . . . cord-285647-9tegcrc3 303 1 The the DT cord-285647-9tegcrc3 303 2 most most RBS cord-285647-9tegcrc3 303 3 efficient efficient JJ cord-285647-9tegcrc3 303 4 way way NN cord-285647-9tegcrc3 303 5 of of IN cord-285647-9tegcrc3 303 6 propagating propagate VBG cord-285647-9tegcrc3 303 7 a a DT cord-285647-9tegcrc3 303 8 perturbation perturbation NN cord-285647-9tegcrc3 303 9 between between IN cord-285647-9tegcrc3 303 10 the the DT cord-285647-9tegcrc3 303 11 nodes node NNS cord-285647-9tegcrc3 303 12 of of IN cord-285647-9tegcrc3 303 13 a a DT cord-285647-9tegcrc3 303 14 network network NN cord-285647-9tegcrc3 303 15 is be VBZ cord-285647-9tegcrc3 303 16 through through IN cord-285647-9tegcrc3 303 17 the the DT cord-285647-9tegcrc3 303 18 shortest short JJS cord-285647-9tegcrc3 303 19 ( ( -LRB- cord-285647-9tegcrc3 303 20 topological topological JJ cord-285647-9tegcrc3 303 21 ) ) -RRB- cord-285647-9tegcrc3 303 22 paths path NNS cord-285647-9tegcrc3 303 23 that that WDT cord-285647-9tegcrc3 303 24 connect connect VBP cord-285647-9tegcrc3 303 25 them -PRON- PRP cord-285647-9tegcrc3 303 26 . . . cord-285647-9tegcrc3 304 1 The the DT cord-285647-9tegcrc3 304 2 problem problem NN cord-285647-9tegcrc3 304 3 for for IN cord-285647-9tegcrc3 304 4 a a DT cord-285647-9tegcrc3 304 5 ( ( -LRB- cord-285647-9tegcrc3 304 6 sub)diffusive sub)diffusive `` cord-285647-9tegcrc3 304 7 perturbation perturbation NN cord-285647-9tegcrc3 304 8 propagating propagate VBG cord-285647-9tegcrc3 304 9 between between IN cord-285647-9tegcrc3 304 10 the the DT cord-285647-9tegcrc3 304 11 nodes node NNS cord-285647-9tegcrc3 304 12 of of IN cord-285647-9tegcrc3 304 13 a a DT cord-285647-9tegcrc3 304 14 network network NN cord-285647-9tegcrc3 304 15 is be VBZ cord-285647-9tegcrc3 304 16 that that IN cord-285647-9tegcrc3 304 17 it -PRON- PRP cord-285647-9tegcrc3 304 18 does do VBZ cord-285647-9tegcrc3 304 19 not not RB cord-285647-9tegcrc3 304 20 have have VB cord-285647-9tegcrc3 304 21 complete complete JJ cord-285647-9tegcrc3 304 22 information information NN cord-285647-9tegcrc3 304 23 about about IN cord-285647-9tegcrc3 304 24 the the DT cord-285647-9tegcrc3 304 25 topology topology NN cord-285647-9tegcrc3 304 26 of of IN cord-285647-9tegcrc3 304 27 the the DT cord-285647-9tegcrc3 304 28 network network NN cord-285647-9tegcrc3 304 29 as as IN cord-285647-9tegcrc3 304 30 to to TO cord-285647-9tegcrc3 304 31 know know VB cord-285647-9tegcrc3 304 32 its -PRON- PRP$ cord-285647-9tegcrc3 304 33 shortest short JJS cord-285647-9tegcrc3 304 34 ( ( -LRB- cord-285647-9tegcrc3 304 35 topological topological JJ cord-285647-9tegcrc3 304 36 ) ) -RRB- cord-285647-9tegcrc3 304 37 paths path NNS cord-285647-9tegcrc3 304 38 . . . cord-285647-9tegcrc3 305 1 The the DT cord-285647-9tegcrc3 305 2 network network NN cord-285647-9tegcrc3 305 3 formed form VBN cord-285647-9tegcrc3 305 4 by by IN cord-285647-9tegcrc3 305 5 the the DT cord-285647-9tegcrc3 305 6 proteins protein NNS cord-285647-9tegcrc3 305 7 targeted target VBN cord-285647-9tegcrc3 305 8 by by IN cord-285647-9tegcrc3 305 9 SARS SARS NNP cord-285647-9tegcrc3 305 10 - - HYPH cord-285647-9tegcrc3 305 11 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 305 12 is be VBZ cord-285647-9tegcrc3 305 13 very very RB cord-285647-9tegcrc3 305 14 sparse sparse JJ cord-285647-9tegcrc3 305 15 , , , cord-285647-9tegcrc3 305 16 and and CC cord-285647-9tegcrc3 305 17 this this DT cord-285647-9tegcrc3 305 18 indeed indeed RB cord-285647-9tegcrc3 305 19 facilitates facilitate VBZ cord-285647-9tegcrc3 305 20 that that IN cord-285647-9tegcrc3 305 21 the the DT cord-285647-9tegcrc3 305 22 perturbations perturbation NNS cord-285647-9tegcrc3 305 23 occurs occur VBZ cord-285647-9tegcrc3 305 24 by by IN cord-285647-9tegcrc3 305 25 following follow VBG cord-285647-9tegcrc3 305 26 the the DT cord-285647-9tegcrc3 305 27 shortest short JJS cord-285647-9tegcrc3 305 28 ( ( -LRB- cord-285647-9tegcrc3 305 29 topological topological JJ cord-285647-9tegcrc3 305 30 ) ) -RRB- cord-285647-9tegcrc3 305 31 paths path NNS cord-285647-9tegcrc3 305 32 most most JJS cord-285647-9tegcrc3 305 33 of of IN cord-285647-9tegcrc3 305 34 the the DT cord-285647-9tegcrc3 305 35 time time NN cord-285647-9tegcrc3 305 36 . . . cord-285647-9tegcrc3 306 1 Think think VB cord-285647-9tegcrc3 306 2 , , , cord-285647-9tegcrc3 306 3 for for IN cord-285647-9tegcrc3 306 4 instance instance NN cord-285647-9tegcrc3 306 5 , , , cord-285647-9tegcrc3 306 6 in in IN cord-285647-9tegcrc3 306 7 a a DT cord-285647-9tegcrc3 306 8 tree tree NN cord-285647-9tegcrc3 306 9 , , , cord-285647-9tegcrc3 306 10 which which WDT cord-285647-9tegcrc3 306 11 has have VBZ cord-285647-9tegcrc3 306 12 the the DT cord-285647-9tegcrc3 306 13 lowest low JJS cord-285647-9tegcrc3 306 14 possible possible JJ cord-285647-9tegcrc3 306 15 edge edge NN cord-285647-9tegcrc3 306 16 density density NN cord-285647-9tegcrc3 306 17 among among IN cord-285647-9tegcrc3 306 18 all all DT cord-285647-9tegcrc3 306 19 connected connect VBN cord-285647-9tegcrc3 306 20 networks network NNS cord-285647-9tegcrc3 306 21 . . . cord-285647-9tegcrc3 307 1 In in IN cord-285647-9tegcrc3 307 2 this this DT cord-285647-9tegcrc3 307 3 case case NN cord-285647-9tegcrc3 307 4 , , , cord-285647-9tegcrc3 307 5 the the DT cord-285647-9tegcrc3 307 6 perturbation perturbation NN cord-285647-9tegcrc3 307 7 will will MD cord-285647-9tegcrc3 307 8 always always RB cord-285647-9tegcrc3 307 9 use use VB cord-285647-9tegcrc3 307 10 the the DT cord-285647-9tegcrc3 307 11 shortest short JJS cord-285647-9tegcrc3 307 12 ( ( -LRB- cord-285647-9tegcrc3 307 13 topological topological JJ cord-285647-9tegcrc3 307 14 ) ) -RRB- cord-285647-9tegcrc3 307 15 paths path NNS cord-285647-9tegcrc3 307 16 connecting connect VBG cord-285647-9tegcrc3 307 17 pairs pair NNS cord-285647-9tegcrc3 307 18 of of IN cord-285647-9tegcrc3 307 19 nodes node NNS cord-285647-9tegcrc3 307 20 . . . cord-285647-9tegcrc3 308 1 However however RB cord-285647-9tegcrc3 308 2 , , , cord-285647-9tegcrc3 308 3 in in IN cord-285647-9tegcrc3 308 4 the the DT cord-285647-9tegcrc3 308 5 case case NN cord-285647-9tegcrc3 308 6 of of IN cord-285647-9tegcrc3 308 7 the the DT cord-285647-9tegcrc3 308 8 PPI PPI NNP cord-285647-9tegcrc3 308 9 network network NN cord-285647-9tegcrc3 308 10 studied study VBD cord-285647-9tegcrc3 308 11 here here RB cord-285647-9tegcrc3 308 12 , , , cord-285647-9tegcrc3 308 13 a a DT cord-285647-9tegcrc3 308 14 normal normal JJ cord-285647-9tegcrc3 308 15 diffusive diffusive JJ cord-285647-9tegcrc3 308 16 process process NN cord-285647-9tegcrc3 308 17 , , , cord-285647-9tegcrc3 308 18 i.e. i.e. FW cord-285647-9tegcrc3 308 19 , , , cord-285647-9tegcrc3 308 20 α α NN cord-285647-9tegcrc3 308 21 = = SYM cord-285647-9tegcrc3 308 22 1 1 CD cord-285647-9tegcrc3 308 23 , , , cord-285647-9tegcrc3 308 24 not not RB cord-285647-9tegcrc3 308 25 always always RB cord-285647-9tegcrc3 308 26 uses use VBZ cord-285647-9tegcrc3 308 27 the the DT cord-285647-9tegcrc3 308 28 shortest short JJS cord-285647-9tegcrc3 308 29 ( ( -LRB- cord-285647-9tegcrc3 308 30 topological topological JJ cord-285647-9tegcrc3 308 31 ) ) -RRB- cord-285647-9tegcrc3 308 32 paths path NNS cord-285647-9tegcrc3 308 33 . . . cord-285647-9tegcrc3 309 1 In in IN cord-285647-9tegcrc3 309 2 this this DT cord-285647-9tegcrc3 309 3 case case NN cord-285647-9tegcrc3 309 4 , , , cord-285647-9tegcrc3 309 5 there there EX cord-285647-9tegcrc3 309 6 are be VBP cord-285647-9tegcrc3 309 7 1294 1294 CD cord-285647-9tegcrc3 309 8 pairs pair NNS cord-285647-9tegcrc3 309 9 of of IN cord-285647-9tegcrc3 309 10 proteins protein NNS cord-285647-9tegcrc3 309 11 for for IN cord-285647-9tegcrc3 309 12 which which WDT cord-285647-9tegcrc3 309 13 the the DT cord-285647-9tegcrc3 309 14 diffusive diffusive JJ cord-285647-9tegcrc3 309 15 particle particle NN cord-285647-9tegcrc3 309 16 uses use VBZ cord-285647-9tegcrc3 309 17 a a DT cord-285647-9tegcrc3 309 18 shortest short JJS cord-285647-9tegcrc3 309 19 diffusive diffusive JJ cord-285647-9tegcrc3 309 20 path path NN cord-285647-9tegcrc3 309 21 , , , cord-285647-9tegcrc3 309 22 which which WDT cord-285647-9tegcrc3 309 23 is be VBZ cord-285647-9tegcrc3 309 24 one one CD cord-285647-9tegcrc3 309 25 edge edge NN cord-285647-9tegcrc3 309 26 longer long RBR cord-285647-9tegcrc3 309 27 than than IN cord-285647-9tegcrc3 309 28 the the DT cord-285647-9tegcrc3 309 29 corresponding correspond VBG cord-285647-9tegcrc3 309 30 shortest short JJS cord-285647-9tegcrc3 309 31 ( ( -LRB- cord-285647-9tegcrc3 309 32 topological topological JJ cord-285647-9tegcrc3 309 33 ) ) -RRB- cord-285647-9tegcrc3 309 34 path path NN cord-285647-9tegcrc3 309 35 . . . cord-285647-9tegcrc3 310 1 This this DT cord-285647-9tegcrc3 310 2 represents represent VBZ cord-285647-9tegcrc3 310 3 6.11 6.11 CD cord-285647-9tegcrc3 310 4 % % NN cord-285647-9tegcrc3 310 5 of of IN cord-285647-9tegcrc3 310 6 all all DT cord-285647-9tegcrc3 310 7 total total JJ cord-285647-9tegcrc3 310 8 pairs pair NNS cord-285647-9tegcrc3 310 9 of of IN cord-285647-9tegcrc3 310 10 proteins protein NNS cord-285647-9tegcrc3 310 11 that that WDT cord-285647-9tegcrc3 310 12 are be VBP cord-285647-9tegcrc3 310 13 interconnected interconnect VBN cord-285647-9tegcrc3 310 14 by by IN cord-285647-9tegcrc3 310 15 a a DT cord-285647-9tegcrc3 310 16 path path NN cord-285647-9tegcrc3 310 17 in in IN cord-285647-9tegcrc3 310 18 the the DT cord-285647-9tegcrc3 310 19 PPI PPI NNP cord-285647-9tegcrc3 310 20 network network NN cord-285647-9tegcrc3 310 21 of of IN cord-285647-9tegcrc3 310 22 proteins protein NNS cord-285647-9tegcrc3 310 23 targeted target VBN cord-285647-9tegcrc3 310 24 by by IN cord-285647-9tegcrc3 310 25 SARS SARS NNP cord-285647-9tegcrc3 310 26 - - HYPH cord-285647-9tegcrc3 310 27 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 310 28 . . . cord-285647-9tegcrc3 311 1 However however RB cord-285647-9tegcrc3 311 2 , , , cord-285647-9tegcrc3 311 3 when when WRB cord-285647-9tegcrc3 311 4 we -PRON- PRP cord-285647-9tegcrc3 311 5 have have VBP cord-285647-9tegcrc3 311 6 a a DT cord-285647-9tegcrc3 311 7 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 311 8 process process NN cord-285647-9tegcrc3 311 9 , , , cord-285647-9tegcrc3 311 10 i.e. i.e. FW cord-285647-9tegcrc3 311 11 , , , cord-285647-9tegcrc3 311 12 α α NN cord-285647-9tegcrc3 311 13 = = SYM cord-285647-9tegcrc3 311 14 0.75 0.75 CD cord-285647-9tegcrc3 311 15 , , , cord-285647-9tegcrc3 311 16 this this DT cord-285647-9tegcrc3 311 17 number number NN cord-285647-9tegcrc3 311 18 is be VBZ cord-285647-9tegcrc3 311 19 reduced reduce VBN cord-285647-9tegcrc3 311 20 to to IN cord-285647-9tegcrc3 311 21 437 437 CD cord-285647-9tegcrc3 311 22 , , , cord-285647-9tegcrc3 311 23 which which WDT cord-285647-9tegcrc3 311 24 represents represent VBZ cord-285647-9tegcrc3 311 25 only only RB cord-285647-9tegcrc3 311 26 2.06 2.06 CD cord-285647-9tegcrc3 311 27 % % NN cord-285647-9tegcrc3 311 28 of of IN cord-285647-9tegcrc3 311 29 all all DT cord-285647-9tegcrc3 311 30 pairs pair NNS cord-285647-9tegcrc3 311 31 of of IN cord-285647-9tegcrc3 311 32 proteins protein NNS cord-285647-9tegcrc3 311 33 . . . cord-285647-9tegcrc3 312 1 Therefore therefore RB cord-285647-9tegcrc3 312 2 , , , cord-285647-9tegcrc3 312 3 the the DT cord-285647-9tegcrc3 312 4 subdiffusion subdiffusion NN cord-285647-9tegcrc3 312 5 process process NN cord-285647-9tegcrc3 312 6 studied study VBN cord-285647-9tegcrc3 312 7 here here RB cord-285647-9tegcrc3 312 8 through through IN cord-285647-9tegcrc3 312 9 the the DT cord-285647-9tegcrc3 312 10 PPI PPI NNP cord-285647-9tegcrc3 312 11 network network NN cord-285647-9tegcrc3 312 12 of of IN cord-285647-9tegcrc3 312 13 proteins protein NNS cord-285647-9tegcrc3 312 14 targeted target VBN cord-285647-9tegcrc3 312 15 by by IN cord-285647-9tegcrc3 312 16 SARS SARS NNP cord-285647-9tegcrc3 312 17 - - HYPH cord-285647-9tegcrc3 312 18 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 312 19 has have VBZ cord-285647-9tegcrc3 312 20 an an DT cord-285647-9tegcrc3 312 21 efficiency efficiency NN cord-285647-9tegcrc3 312 22 of of IN cord-285647-9tegcrc3 312 23 97.9 97.9 CD cord-285647-9tegcrc3 312 24 % % NN cord-285647-9tegcrc3 312 25 relative relative JJ cord-285647-9tegcrc3 312 26 to to IN cord-285647-9tegcrc3 312 27 a a DT cord-285647-9tegcrc3 312 28 process process NN cord-285647-9tegcrc3 312 29 that that WDT cord-285647-9tegcrc3 312 30 always always RB cord-285647-9tegcrc3 312 31 uses use VBZ cord-285647-9tegcrc3 312 32 the the DT cord-285647-9tegcrc3 312 33 shortest short JJS cord-285647-9tegcrc3 312 34 ( ( -LRB- cord-285647-9tegcrc3 312 35 topological topological JJ cord-285647-9tegcrc3 312 36 ) ) -RRB- cord-285647-9tegcrc3 312 37 paths path NNS cord-285647-9tegcrc3 312 38 in in IN cord-285647-9tegcrc3 312 39 hopping hop VBG cord-285647-9tegcrc3 312 40 between between IN cord-285647-9tegcrc3 312 41 proteins protein NNS cord-285647-9tegcrc3 312 42 . . . cord-285647-9tegcrc3 313 1 In in IN cord-285647-9tegcrc3 313 2 Fig Fig NNP cord-285647-9tegcrc3 313 3 . . . cord-285647-9tegcrc3 314 1 5 5 LS cord-285647-9tegcrc3 314 2 , , , cord-285647-9tegcrc3 314 3 we -PRON- PRP cord-285647-9tegcrc3 314 4 illustrate illustrate VBP cord-285647-9tegcrc3 314 5 the the DT cord-285647-9tegcrc3 314 6 frequency frequency NN cord-285647-9tegcrc3 314 7 with with IN cord-285647-9tegcrc3 314 8 which which WDT cord-285647-9tegcrc3 314 9 proteins protein NNS cord-285647-9tegcrc3 314 10 not not RB cord-285647-9tegcrc3 314 11 in in IN cord-285647-9tegcrc3 314 12 the the DT cord-285647-9tegcrc3 314 13 shortest short JJS cord-285647-9tegcrc3 314 14 ( ( -LRB- cord-285647-9tegcrc3 314 15 topological topological JJ cord-285647-9tegcrc3 314 16 ) ) -RRB- cord-285647-9tegcrc3 314 17 paths path NNS cord-285647-9tegcrc3 314 18 are be VBP cord-285647-9tegcrc3 314 19 perturbed perturb VBN cord-285647-9tegcrc3 314 20 as as IN cord-285647-9tegcrc3 314 21 a a DT cord-285647-9tegcrc3 314 22 consequence consequence NN cord-285647-9tegcrc3 314 23 that that IN cord-285647-9tegcrc3 314 24 they -PRON- PRP cord-285647-9tegcrc3 314 25 are be VBP cord-285647-9tegcrc3 314 26 in in IN cord-285647-9tegcrc3 314 27 the the DT cord-285647-9tegcrc3 314 28 shortest short JJS cord-285647-9tegcrc3 314 29 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 314 30 paths path NNS cord-285647-9tegcrc3 314 31 between between IN cord-285647-9tegcrc3 314 32 other other JJ cord-285647-9tegcrc3 314 33 proteins protein NNS cord-285647-9tegcrc3 314 34 . . . cord-285647-9tegcrc3 315 1 For for IN cord-285647-9tegcrc3 315 2 instance instance NN cord-285647-9tegcrc3 315 3 , , , cord-285647-9tegcrc3 315 4 the the DT cord-285647-9tegcrc3 315 5 following follow VBG cord-285647-9tegcrc3 315 6 is be VBZ cord-285647-9tegcrc3 315 7 a a DT cord-285647-9tegcrc3 315 8 shortest short JJS cord-285647-9tegcrc3 315 9 diffusive diffusive JJ cord-285647-9tegcrc3 315 10 path path NN cord-285647-9tegcrc3 315 11 between between IN cord-285647-9tegcrc3 315 12 the the DT cord-285647-9tegcrc3 315 13 two two CD cord-285647-9tegcrc3 315 14 end end NN cord-285647-9tegcrc3 315 15 points point NNS cord-285647-9tegcrc3 315 16 : : : cord-285647-9tegcrc3 315 17 RHOA rhoa NN cord-285647-9tegcrc3 315 18 - - HYPH cord-285647-9tegcrc3 315 19 PRKACA PRKACA NNP cord-285647-9tegcrc3 315 20 - - HYPH cord-285647-9tegcrc3 315 21 PRKAR2A PRKAR2A NNP cord-285647-9tegcrc3 315 22 - - HYPH cord-285647-9tegcrc3 315 23 CEP43-RAB7A CEP43-RAB7A NNP cord-285647-9tegcrc3 315 24 - - HYPH cord-285647-9tegcrc3 315 25 ATP6AP1 ATP6AP1 NNP cord-285647-9tegcrc3 315 26 . . . cord-285647-9tegcrc3 316 1 The the DT cord-285647-9tegcrc3 316 2 corresponding correspond VBG cord-285647-9tegcrc3 316 3 shortest short JJS cord-285647-9tegcrc3 316 4 ( ( -LRB- cord-285647-9tegcrc3 316 5 topological topological JJ cord-285647-9tegcrc3 316 6 ) ) -RRB- cord-285647-9tegcrc3 316 7 path path NN cord-285647-9tegcrc3 316 8 is be VBZ cord-285647-9tegcrc3 316 9 RHOA rhoa NN cord-285647-9tegcrc3 316 10 - - HYPH cord-285647-9tegcrc3 316 11 MARK2-AP2M1-RAB7A MARK2-AP2M1-RAB7A NNP cord-285647-9tegcrc3 316 12 - - HYPH cord-285647-9tegcrc3 316 13 ATP6AP1 ATP6AP1 NNP cord-285647-9tegcrc3 316 14 , , , cord-285647-9tegcrc3 316 15 which which WDT cord-285647-9tegcrc3 316 16 is be VBZ cord-285647-9tegcrc3 316 17 one one CD cord-285647-9tegcrc3 316 18 edge edge NN cord-285647-9tegcrc3 316 19 smaller small JJR cord-285647-9tegcrc3 316 20 . . . cord-285647-9tegcrc3 317 1 The the DT cord-285647-9tegcrc3 317 2 proteins protein NNS cord-285647-9tegcrc3 317 3 PRKACA PRKACA NNP cord-285647-9tegcrc3 317 4 , , , cord-285647-9tegcrc3 317 5 PRKAR2A prkar2a JJ cord-285647-9tegcrc3 317 6 , , , cord-285647-9tegcrc3 317 7 and and CC cord-285647-9tegcrc3 317 8 CEP43 CEP43 NNP cord-285647-9tegcrc3 317 9 are be VBP cord-285647-9tegcrc3 317 10 those those DT cord-285647-9tegcrc3 317 11 in in IN cord-285647-9tegcrc3 317 12 the the DT cord-285647-9tegcrc3 317 13 diffusive diffusive JJ cord-285647-9tegcrc3 317 14 path path NN cord-285647-9tegcrc3 317 15 that that WDT cord-285647-9tegcrc3 317 16 are be VBP cord-285647-9tegcrc3 317 17 not not RB cord-285647-9tegcrc3 317 18 in in IN cord-285647-9tegcrc3 317 19 the the DT cord-285647-9tegcrc3 317 20 topological topological JJ cord-285647-9tegcrc3 317 21 one one CD cord-285647-9tegcrc3 317 22 . . . cord-285647-9tegcrc3 318 1 Repeating repeat VBG cord-285647-9tegcrc3 318 2 this this DT cord-285647-9tegcrc3 318 3 selection selection NN cord-285647-9tegcrc3 318 4 process process NN cord-285647-9tegcrc3 318 5 for for IN cord-285647-9tegcrc3 318 6 all all PDT cord-285647-9tegcrc3 318 7 the the DT cord-285647-9tegcrc3 318 8 diffusive diffusive JJ cord-285647-9tegcrc3 318 9 paths path NNS cord-285647-9tegcrc3 318 10 that that WDT cord-285647-9tegcrc3 318 11 differs differ VBZ cord-285647-9tegcrc3 318 12 from from IN cord-285647-9tegcrc3 318 13 the the DT cord-285647-9tegcrc3 318 14 topological topological JJ cord-285647-9tegcrc3 318 15 ones one NNS cord-285647-9tegcrc3 318 16 , , , cord-285647-9tegcrc3 318 17 we -PRON- PRP cord-285647-9tegcrc3 318 18 obtained obtain VBD cord-285647-9tegcrc3 318 19 the the DT cord-285647-9tegcrc3 318 20 results result NNS cord-285647-9tegcrc3 318 21 illustrated illustrate VBN cord-285647-9tegcrc3 318 22 in in IN cord-285647-9tegcrc3 318 23 Fig Fig NNP cord-285647-9tegcrc3 318 24 . . . cord-285647-9tegcrc3 319 1 5 5 LS cord-285647-9tegcrc3 319 2 . . . cord-285647-9tegcrc3 320 1 As as IN cord-285647-9tegcrc3 320 2 can can MD cord-285647-9tegcrc3 320 3 be be VB cord-285647-9tegcrc3 320 4 seen see VBN cord-285647-9tegcrc3 320 5 , , , cord-285647-9tegcrc3 320 6 there there EX cord-285647-9tegcrc3 320 7 are be VBP cord-285647-9tegcrc3 320 8 36 36 CD cord-285647-9tegcrc3 320 9 proteins protein NNS cord-285647-9tegcrc3 320 10 visited visit VBN cord-285647-9tegcrc3 320 11 by by IN cord-285647-9tegcrc3 320 12 the the DT cord-285647-9tegcrc3 320 13 shortest short JJS cord-285647-9tegcrc3 320 14 diffusive diffusive JJ cord-285647-9tegcrc3 320 15 paths path NNS cord-285647-9tegcrc3 320 16 , , , cord-285647-9tegcrc3 320 17 which which WDT cord-285647-9tegcrc3 320 18 are be VBP cord-285647-9tegcrc3 320 19 not not RB cord-285647-9tegcrc3 320 20 visited visit VBN cord-285647-9tegcrc3 320 21 by by IN cord-285647-9tegcrc3 320 22 the the DT cord-285647-9tegcrc3 320 23 corresponding corresponding JJ cord-285647-9tegcrc3 320 24 topological topological JJ cord-285647-9tegcrc3 320 25 ones one NNS cord-285647-9tegcrc3 320 26 . . . cord-285647-9tegcrc3 321 1 The the DT cord-285647-9tegcrc3 321 2 Chaos Chaos NNP cord-285647-9tegcrc3 321 3 ARTICLE article NN cord-285647-9tegcrc3 321 4 scitation.org/journal/cha scitation.org/journal/cha CD cord-285647-9tegcrc3 322 1 average average JJ cord-285647-9tegcrc3 322 2 degree degree NN cord-285647-9tegcrc3 322 3 of of IN cord-285647-9tegcrc3 322 4 these these DT cord-285647-9tegcrc3 322 5 proteins protein NNS cord-285647-9tegcrc3 322 6 is be VBZ cord-285647-9tegcrc3 322 7 7.28 7.28 CD cord-285647-9tegcrc3 322 8 , , , cord-285647-9tegcrc3 322 9 and and CC cord-285647-9tegcrc3 322 10 there there EX cord-285647-9tegcrc3 322 11 is be VBZ cord-285647-9tegcrc3 322 12 only only RB cord-285647-9tegcrc3 322 13 a a DT cord-285647-9tegcrc3 322 14 small small JJ cord-285647-9tegcrc3 322 15 positive positive JJ cord-285647-9tegcrc3 322 16 trend trend NN cord-285647-9tegcrc3 322 17 between between IN cord-285647-9tegcrc3 322 18 the the DT cord-285647-9tegcrc3 322 19 degree degree NN cord-285647-9tegcrc3 322 20 of of IN cord-285647-9tegcrc3 322 21 the the DT cord-285647-9tegcrc3 322 22 proteins protein NNS cord-285647-9tegcrc3 322 23 and and CC cord-285647-9tegcrc3 322 24 the the DT cord-285647-9tegcrc3 322 25 frequency frequency NN cord-285647-9tegcrc3 322 26 with with IN cord-285647-9tegcrc3 322 27 which which WDT cord-285647-9tegcrc3 322 28 they -PRON- PRP cord-285647-9tegcrc3 322 29 appear appear VBP cord-285647-9tegcrc3 322 30 in in IN cord-285647-9tegcrc3 322 31 these these DT cord-285647-9tegcrc3 322 32 paths path NNS cord-285647-9tegcrc3 322 33 ; ; : cord-285647-9tegcrc3 322 34 e.g. e.g. RB cord-285647-9tegcrc3 322 35 , , , cord-285647-9tegcrc3 322 36 the the DT cord-285647-9tegcrc3 322 37 Pearson Pearson NNP cord-285647-9tegcrc3 322 38 correlation correlation NN cord-285647-9tegcrc3 322 39 coefficient coefficient NN cord-285647-9tegcrc3 322 40 is be VBZ cord-285647-9tegcrc3 322 41 0.46 0.46 CD cord-285647-9tegcrc3 322 42 . . . cord-285647-9tegcrc3 323 1 We -PRON- PRP cord-285647-9tegcrc3 323 2 have have VBP cord-285647-9tegcrc3 323 3 presented present VBN cord-285647-9tegcrc3 323 4 a a DT cord-285647-9tegcrc3 323 5 methodology methodology NN cord-285647-9tegcrc3 323 6 that that WDT cord-285647-9tegcrc3 323 7 allows allow VBZ cord-285647-9tegcrc3 323 8 the the DT cord-285647-9tegcrc3 323 9 study study NN cord-285647-9tegcrc3 323 10 of of IN cord-285647-9tegcrc3 323 11 diffusive diffusive JJ cord-285647-9tegcrc3 323 12 processes process NNS cord-285647-9tegcrc3 323 13 in in IN cord-285647-9tegcrc3 323 14 ( ( -LRB- cord-285647-9tegcrc3 323 15 PPI PPI NNP cord-285647-9tegcrc3 323 16 ) ) -RRB- cord-285647-9tegcrc3 323 17 networks network NNS cord-285647-9tegcrc3 323 18 varying vary VBG cord-285647-9tegcrc3 323 19 from from IN cord-285647-9tegcrc3 323 20 normal normal JJ cord-285647-9tegcrc3 323 21 to to IN cord-285647-9tegcrc3 323 22 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 323 23 regimes regime NNS cord-285647-9tegcrc3 323 24 . . . cord-285647-9tegcrc3 324 1 Here here RB cord-285647-9tegcrc3 324 2 , , , cord-285647-9tegcrc3 324 3 we -PRON- PRP cord-285647-9tegcrc3 324 4 have have VBP cord-285647-9tegcrc3 324 5 studied study VBN cord-285647-9tegcrc3 324 6 the the DT cord-285647-9tegcrc3 324 7 particular particular JJ cord-285647-9tegcrc3 324 8 case case NN cord-285647-9tegcrc3 324 9 in in IN cord-285647-9tegcrc3 324 10 which which WDT cord-285647-9tegcrc3 324 11 the the DT cord-285647-9tegcrc3 324 12 time time NN cord-285647-9tegcrc3 324 13 - - HYPH cord-285647-9tegcrc3 324 14 fractional fractional JJ cord-285647-9tegcrc3 324 15 diffusion diffusion NN cord-285647-9tegcrc3 324 16 equation equation NN cord-285647-9tegcrc3 324 17 produces produce VBZ cord-285647-9tegcrc3 324 18 a a DT cord-285647-9tegcrc3 324 19 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 324 20 regime regime NN cord-285647-9tegcrc3 324 21 , , , cord-285647-9tegcrc3 324 22 with with IN cord-285647-9tegcrc3 324 23 the the DT cord-285647-9tegcrc3 324 24 use use NN cord-285647-9tegcrc3 324 25 of of IN cord-285647-9tegcrc3 324 26 α α NN cord-285647-9tegcrc3 324 27 = = SYM cord-285647-9tegcrc3 324 28 3/4 3/4 CD cord-285647-9tegcrc3 324 29 in in IN cord-285647-9tegcrc3 324 30 the the DT cord-285647-9tegcrc3 324 31 network network NN cord-285647-9tegcrc3 324 32 of of IN cord-285647-9tegcrc3 324 33 human human JJ cord-285647-9tegcrc3 324 34 proteins protein NNS cord-285647-9tegcrc3 324 35 targeted target VBN cord-285647-9tegcrc3 324 36 by by IN cord-285647-9tegcrc3 324 37 SARS SARS NNP cord-285647-9tegcrc3 324 38 - - HYPH cord-285647-9tegcrc3 324 39 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 324 40 . . . cord-285647-9tegcrc3 325 1 A a DT cord-285647-9tegcrc3 325 2 characteristic characteristic JJ cord-285647-9tegcrc3 325 3 feature feature NN cord-285647-9tegcrc3 325 4 of of IN cord-285647-9tegcrc3 325 5 this this DT cord-285647-9tegcrc3 325 6 PPI PPI NNP cord-285647-9tegcrc3 325 7 network network NN cord-285647-9tegcrc3 325 8 is be VBZ cord-285647-9tegcrc3 325 9 that that IN cord-285647-9tegcrc3 325 10 the the DT cord-285647-9tegcrc3 325 11 second second JJ cord-285647-9tegcrc3 325 12 smallest small JJS cord-285647-9tegcrc3 325 13 eigenvalue eigenvalue NN cord-285647-9tegcrc3 325 14 is be VBZ cord-285647-9tegcrc3 325 15 very very RB cord-285647-9tegcrc3 325 16 small small JJ cord-285647-9tegcrc3 325 17 ; ; : cord-285647-9tegcrc3 325 18 i.e. i.e. FW cord-285647-9tegcrc3 325 19 , , , cord-285647-9tegcrc3 325 20 µ µ NN cord-285647-9tegcrc3 325 21 2 2 CD cord-285647-9tegcrc3 325 22 = = SYM cord-285647-9tegcrc3 325 23 0.0647 0.0647 CD cord-285647-9tegcrc3 325 24 . . . cord-285647-9tegcrc3 326 1 As as IN cord-285647-9tegcrc3 326 2 this this DT cord-285647-9tegcrc3 326 3 eigenvalue eigenvalue NN cord-285647-9tegcrc3 326 4 determines determine VBZ cord-285647-9tegcrc3 326 5 the the DT cord-285647-9tegcrc3 326 6 rate rate NN cord-285647-9tegcrc3 326 7 of of IN cord-285647-9tegcrc3 326 8 convergence convergence NN cord-285647-9tegcrc3 326 9 to to IN cord-285647-9tegcrc3 326 10 the the DT cord-285647-9tegcrc3 326 11 steady steady JJ cord-285647-9tegcrc3 326 12 state state NN cord-285647-9tegcrc3 326 13 , , , cord-285647-9tegcrc3 326 14 the the DT cord-285647-9tegcrc3 326 15 subdiffusive subdiffusive NN cord-285647-9tegcrc3 326 16 process process NN cord-285647-9tegcrc3 326 17 converges converge VBZ cord-285647-9tegcrc3 326 18 very very RB cord-285647-9tegcrc3 326 19 slowly slowly RB cord-285647-9tegcrc3 326 20 to to IN cord-285647-9tegcrc3 326 21 that that DT cord-285647-9tegcrc3 326 22 state state NN cord-285647-9tegcrc3 326 23 . . . cord-285647-9tegcrc3 327 1 What what WP cord-285647-9tegcrc3 327 2 it -PRON- PRP cord-285647-9tegcrc3 327 3 has have VBZ cord-285647-9tegcrc3 327 4 been be VBN cord-285647-9tegcrc3 327 5 surprising surprising JJ cord-285647-9tegcrc3 327 6 is be VBZ cord-285647-9tegcrc3 327 7 that that IN cord-285647-9tegcrc3 327 8 even even RB cord-285647-9tegcrc3 327 9 in in IN cord-285647-9tegcrc3 327 10 these these DT cord-285647-9tegcrc3 327 11 conditions condition NNS cord-285647-9tegcrc3 327 12 of of IN cord-285647-9tegcrc3 327 13 very very RB cord-285647-9tegcrc3 327 14 small small JJ cord-285647-9tegcrc3 327 15 convergence convergence NN cord-285647-9tegcrc3 327 16 to to IN cord-285647-9tegcrc3 327 17 the the DT cord-285647-9tegcrc3 327 18 steady steady JJ cord-285647-9tegcrc3 327 19 state state NN cord-285647-9tegcrc3 327 20 , , , cord-285647-9tegcrc3 327 21 there there EX cord-285647-9tegcrc3 327 22 is be VBZ cord-285647-9tegcrc3 327 23 a a DT cord-285647-9tegcrc3 327 24 very very RB cord-285647-9tegcrc3 327 25 early early JJ cord-285647-9tegcrc3 327 26 increase increase NN cord-285647-9tegcrc3 327 27 of of IN cord-285647-9tegcrc3 327 28 the the DT cord-285647-9tegcrc3 327 29 probability probability NN cord-285647-9tegcrc3 327 30 in in IN cord-285647-9tegcrc3 327 31 those those DT cord-285647-9tegcrc3 327 32 proteins protein NNS cord-285647-9tegcrc3 327 33 closely closely RB cord-285647-9tegcrc3 327 34 connected connect VBN cord-285647-9tegcrc3 327 35 to to IN cord-285647-9tegcrc3 327 36 the the DT cord-285647-9tegcrc3 327 37 initiator initiator NN cord-285647-9tegcrc3 327 38 of of IN cord-285647-9tegcrc3 327 39 the the DT cord-285647-9tegcrc3 327 40 diffusive diffusive JJ cord-285647-9tegcrc3 327 41 process process NN cord-285647-9tegcrc3 327 42 . . . cord-285647-9tegcrc3 328 1 That that RB cord-285647-9tegcrc3 328 2 is is RB cord-285647-9tegcrc3 328 3 , , , cord-285647-9tegcrc3 328 4 in in IN cord-285647-9tegcrc3 328 5 a a DT cord-285647-9tegcrc3 328 6 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 328 7 process process NN cord-285647-9tegcrc3 328 8 on on IN cord-285647-9tegcrc3 328 9 a a DT cord-285647-9tegcrc3 328 10 network network NN cord-285647-9tegcrc3 328 11 , , , cord-285647-9tegcrc3 328 12 the the DT cord-285647-9tegcrc3 328 13 time time NN cord-285647-9tegcrc3 328 14 at at IN cord-285647-9tegcrc3 328 15 which which WDT cord-285647-9tegcrc3 328 16 a a DT cord-285647-9tegcrc3 328 17 perturbation perturbation NN cord-285647-9tegcrc3 328 18 is be VBZ cord-285647-9tegcrc3 328 19 transmitted transmit VBN cord-285647-9tegcrc3 328 20 from from IN cord-285647-9tegcrc3 328 21 the the DT cord-285647-9tegcrc3 328 22 initiator initiator NN cord-285647-9tegcrc3 328 23 to to IN cord-285647-9tegcrc3 328 24 any any DT cord-285647-9tegcrc3 328 25 of of IN cord-285647-9tegcrc3 328 26 its -PRON- PRP$ cord-285647-9tegcrc3 328 27 nearest near JJS cord-285647-9tegcrc3 328 28 neighbors neighbor NNS cord-285647-9tegcrc3 328 29 occurs occur VBZ cord-285647-9tegcrc3 328 30 at at IN cord-285647-9tegcrc3 328 31 an an DT cord-285647-9tegcrc3 328 32 earlier early JJR cord-285647-9tegcrc3 328 33 time time NN cord-285647-9tegcrc3 328 34 than than IN cord-285647-9tegcrc3 328 35 for for IN cord-285647-9tegcrc3 328 36 the the DT cord-285647-9tegcrc3 328 37 normal normal JJ cord-285647-9tegcrc3 328 38 diffusion diffusion NN cord-285647-9tegcrc3 328 39 . . . cord-285647-9tegcrc3 329 1 This this DT cord-285647-9tegcrc3 329 2 is be VBZ cord-285647-9tegcrc3 329 3 a a DT cord-285647-9tegcrc3 329 4 consequence consequence NN cord-285647-9tegcrc3 329 5 of of IN cord-285647-9tegcrc3 329 6 the the DT cord-285647-9tegcrc3 329 7 fact fact NN cord-285647-9tegcrc3 329 8 that that IN cord-285647-9tegcrc3 329 9 E e NN cord-285647-9tegcrc3 329 10 α,1 α,1 FW cord-285647-9tegcrc3 329 11 ( ( -LRB- cord-285647-9tegcrc3 329 12 −γ −γ JJ cord-285647-9tegcrc3 329 13 t t NN cord-285647-9tegcrc3 329 14 α α NN cord-285647-9tegcrc3 329 15 ) ) -RRB- cord-285647-9tegcrc3 329 16 decreases decrease VBZ cord-285647-9tegcrc3 329 17 very very RB cord-285647-9tegcrc3 329 18 fast fast RB cord-285647-9tegcrc3 329 19 at at IN cord-285647-9tegcrc3 329 20 small small JJ cord-285647-9tegcrc3 329 21 values value NNS cord-285647-9tegcrc3 329 22 of of IN cord-285647-9tegcrc3 329 23 t t NN cord-285647-9tegcrc3 329 24 α α NN cord-285647-9tegcrc3 329 25 , , , cord-285647-9tegcrc3 329 26 which which WDT cord-285647-9tegcrc3 329 27 implies imply VBZ cord-285647-9tegcrc3 329 28 that that IN cord-285647-9tegcrc3 329 29 the the DT cord-285647-9tegcrc3 329 30 perturbation perturbation NN cord-285647-9tegcrc3 329 31 occurring occur VBG cord-285647-9tegcrc3 329 32 at at IN cord-285647-9tegcrc3 329 33 a a DT cord-285647-9tegcrc3 329 34 protein protein NN cord-285647-9tegcrc3 330 1 i i PRP cord-285647-9tegcrc3 330 2 at at IN cord-285647-9tegcrc3 330 3 t t NN cord-285647-9tegcrc3 330 4 = = SYM cord-285647-9tegcrc3 330 5 0 0 NFP cord-285647-9tegcrc3 330 6 is be VBZ cord-285647-9tegcrc3 330 7 transmitted transmit VBN cord-285647-9tegcrc3 330 8 almost almost RB cord-285647-9tegcrc3 330 9 instantaneously instantaneously RB cord-285647-9tegcrc3 330 10 to to IN cord-285647-9tegcrc3 330 11 the the DT cord-285647-9tegcrc3 330 12 proteins protein NNS cord-285647-9tegcrc3 330 13 closely closely RB cord-285647-9tegcrc3 330 14 connected connect VBN cord-285647-9tegcrc3 330 15 to to IN cord-285647-9tegcrc3 330 16 i. i. NN cord-285647-9tegcrc3 331 1 This this DT cord-285647-9tegcrc3 331 2 effect effect NN cord-285647-9tegcrc3 331 3 may may MD cord-285647-9tegcrc3 331 4 be be VB cord-285647-9tegcrc3 331 5 responsible responsible JJ cord-285647-9tegcrc3 331 6 for for IN cord-285647-9tegcrc3 331 7 the the DT cord-285647-9tegcrc3 331 8 explanation explanation NN cord-285647-9tegcrc3 331 9 about about IN cord-285647-9tegcrc3 331 10 why why WRB cord-285647-9tegcrc3 331 11 subdiffusive subdiffusive NNP cord-285647-9tegcrc3 331 12 processes process NNS cord-285647-9tegcrc3 331 13 , , , cord-285647-9tegcrc3 331 14 which which WDT cord-285647-9tegcrc3 331 15 are be VBP cord-285647-9tegcrc3 331 16 so so RB cord-285647-9tegcrc3 331 17 globally globally RB cord-285647-9tegcrc3 331 18 slow slow JJ cord-285647-9tegcrc3 331 19 , , , cord-285647-9tegcrc3 331 20 can can MD cord-285647-9tegcrc3 331 21 carry carry VB cord-285647-9tegcrc3 331 22 out out RP cord-285647-9tegcrc3 331 23 cellular cellular JJ cord-285647-9tegcrc3 331 24 processes process NNS cord-285647-9tegcrc3 331 25 at at IN cord-285647-9tegcrc3 331 26 a a DT cord-285647-9tegcrc3 331 27 significant significant JJ cord-285647-9tegcrc3 331 28 rate rate NN cord-285647-9tegcrc3 331 29 in in IN cord-285647-9tegcrc3 331 30 cells cell NNS cord-285647-9tegcrc3 331 31 . . . cord-285647-9tegcrc3 332 1 We -PRON- PRP cord-285647-9tegcrc3 332 2 have have VBP cord-285647-9tegcrc3 332 3 considered consider VBN cord-285647-9tegcrc3 332 4 here here RB cord-285647-9tegcrc3 332 5 a a DT cord-285647-9tegcrc3 332 6 mechanism mechanism NN cord-285647-9tegcrc3 332 7 consisting consist VBG cord-285647-9tegcrc3 332 8 in in IN cord-285647-9tegcrc3 332 9 switching switch VBG cord-285647-9tegcrc3 332 10 and and CC cord-285647-9tegcrc3 332 11 restarting restart VBG cord-285647-9tegcrc3 332 12 several several JJ cord-285647-9tegcrc3 332 13 times time NNS cord-285647-9tegcrc3 332 14 during during IN cord-285647-9tegcrc3 332 15 the the DT cord-285647-9tegcrc3 332 16 global global JJ cord-285647-9tegcrc3 332 17 cellular cellular JJ cord-285647-9tegcrc3 332 18 process process NN cord-285647-9tegcrc3 332 19 . . . cord-285647-9tegcrc3 333 1 For for IN cord-285647-9tegcrc3 333 2 instance instance NN cord-285647-9tegcrc3 333 3 , , , cord-285647-9tegcrc3 333 4 a a DT cord-285647-9tegcrc3 333 5 subdiffusive subdiffusive NN cord-285647-9tegcrc3 333 6 process process NN cord-285647-9tegcrc3 333 7 starting start VBG cord-285647-9tegcrc3 333 8 at at IN cord-285647-9tegcrc3 333 9 the the DT cord-285647-9tegcrc3 333 10 protein protein NN cord-285647-9tegcrc3 333 11 i i PRP cord-285647-9tegcrc3 333 12 perturbs perturb VBZ cord-285647-9tegcrc3 333 13 its -PRON- PRP$ cord-285647-9tegcrc3 333 14 nearest near JJS cord-285647-9tegcrc3 333 15 neighbors neighbor NNS cord-285647-9tegcrc3 333 16 at at IN cord-285647-9tegcrc3 333 17 very very RB cord-285647-9tegcrc3 333 18 early early JJ cord-285647-9tegcrc3 333 19 times time NNS cord-285647-9tegcrc3 333 20 , , , cord-285647-9tegcrc3 333 21 among among IN cord-285647-9tegcrc3 333 22 which which WDT cord-285647-9tegcrc3 333 23 we -PRON- PRP cord-285647-9tegcrc3 333 24 can can MD cord-285647-9tegcrc3 333 25 find find VB cord-285647-9tegcrc3 333 26 the the DT cord-285647-9tegcrc3 333 27 protein protein NN cord-285647-9tegcrc3 334 1 j. j. NNP cord-285647-9tegcrc3 334 2 Then then RB cord-285647-9tegcrc3 334 3 , , , cord-285647-9tegcrc3 334 4 a a DT cord-285647-9tegcrc3 334 5 new new JJ cord-285647-9tegcrc3 334 6 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 334 7 process process NN cord-285647-9tegcrc3 334 8 can can MD cord-285647-9tegcrc3 334 9 be be VB cord-285647-9tegcrc3 334 10 restarted restart VBN cord-285647-9tegcrc3 334 11 again again RB cord-285647-9tegcrc3 334 12 at at IN cord-285647-9tegcrc3 334 13 the the DT cord-285647-9tegcrc3 334 14 node node NN cord-285647-9tegcrc3 334 15 j j NNP cord-285647-9tegcrc3 334 16 and and CC cord-285647-9tegcrc3 334 17 so so RB cord-285647-9tegcrc3 334 18 on on RB cord-285647-9tegcrc3 334 19 . . . cord-285647-9tegcrc3 335 1 One one CD cord-285647-9tegcrc3 335 2 of of IN cord-285647-9tegcrc3 335 3 the the DT cord-285647-9tegcrc3 335 4 important important JJ cord-285647-9tegcrc3 335 5 findings finding NNS cord-285647-9tegcrc3 335 6 of of IN cord-285647-9tegcrc3 335 7 using use VBG cord-285647-9tegcrc3 335 8 the the DT cord-285647-9tegcrc3 335 9 current current JJ cord-285647-9tegcrc3 335 10 model model NN cord-285647-9tegcrc3 335 11 for for IN cord-285647-9tegcrc3 335 12 the the DT cord-285647-9tegcrc3 335 13 study study NN cord-285647-9tegcrc3 335 14 of of IN cord-285647-9tegcrc3 335 15 the the DT cord-285647-9tegcrc3 335 16 PIN pin NN cord-285647-9tegcrc3 335 17 of of IN cord-285647-9tegcrc3 335 18 proteins protein NNS cord-285647-9tegcrc3 335 19 affected affect VBN cord-285647-9tegcrc3 335 20 by by IN cord-285647-9tegcrc3 335 21 SARS SARS NNP cord-285647-9tegcrc3 335 22 - - HYPH cord-285647-9tegcrc3 335 23 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 335 24 is be VBZ cord-285647-9tegcrc3 335 25 the the DT cord-285647-9tegcrc3 335 26 identification identification NN cord-285647-9tegcrc3 335 27 of of IN cord-285647-9tegcrc3 335 28 those those DT cord-285647-9tegcrc3 335 29 proteins protein NNS cord-285647-9tegcrc3 335 30 that that WDT cord-285647-9tegcrc3 335 31 are be VBP cord-285647-9tegcrc3 335 32 expressed express VBN cord-285647-9tegcrc3 335 33 outside outside IN cord-285647-9tegcrc3 335 34 the the DT cord-285647-9tegcrc3 335 35 lungs lung NNS cord-285647-9tegcrc3 335 36 that that WDT cord-285647-9tegcrc3 335 37 can can MD cord-285647-9tegcrc3 335 38 be be VB cord-285647-9tegcrc3 335 39 more more RBR cord-285647-9tegcrc3 335 40 efficiently efficiently RB cord-285647-9tegcrc3 335 41 perturbed perturb VBN cord-285647-9tegcrc3 335 42 by by IN cord-285647-9tegcrc3 335 43 those those DT cord-285647-9tegcrc3 335 44 expressed express VBN cord-285647-9tegcrc3 335 45 in in IN cord-285647-9tegcrc3 335 46 the the DT cord-285647-9tegcrc3 335 47 lungs lung NNS cord-285647-9tegcrc3 335 48 ( ( -LRB- cord-285647-9tegcrc3 335 49 see see VB cord-285647-9tegcrc3 335 50 Table table NN cord-285647-9tegcrc3 335 51 I -PRON- PRP cord-285647-9tegcrc3 335 52 ) ) -RRB- cord-285647-9tegcrc3 335 53 . . . cord-285647-9tegcrc3 336 1 For for IN cord-285647-9tegcrc3 336 2 instance instance NN cord-285647-9tegcrc3 336 3 , , , cord-285647-9tegcrc3 336 4 the the DT cord-285647-9tegcrc3 336 5 protein protein NN cord-285647-9tegcrc3 336 6 with with IN cord-285647-9tegcrc3 336 7 the the DT cord-285647-9tegcrc3 336 8 largest large JJS cord-285647-9tegcrc3 336 9 number number NN cord-285647-9tegcrc3 336 10 of of IN cord-285647-9tegcrc3 336 11 activators activator NNS cord-285647-9tegcrc3 336 12 , , , cord-285647-9tegcrc3 336 13 PKP2 PKP2 NNP cord-285647-9tegcrc3 336 14 , , , cord-285647-9tegcrc3 336 15 appears appear VBZ cord-285647-9tegcrc3 336 16 mainly mainly RB cord-285647-9tegcrc3 336 17 in in IN cord-285647-9tegcrc3 336 18 the the DT cord-285647-9tegcrc3 336 19 heart heart NN cord-285647-9tegcrc3 336 20 muscle muscle NN cord-285647-9tegcrc3 336 21 . . . cord-285647-9tegcrc3 337 1 It -PRON- PRP cord-285647-9tegcrc3 337 2 has have VBZ cord-285647-9tegcrc3 337 3 been be VBN cord-285647-9tegcrc3 337 4 observed observe VBN cord-285647-9tegcrc3 337 5 that that IN cord-285647-9tegcrc3 337 6 the the DT cord-285647-9tegcrc3 337 7 elevation elevation NN cord-285647-9tegcrc3 337 8 of of IN cord-285647-9tegcrc3 337 9 cardiac cardiac JJ cord-285647-9tegcrc3 337 10 biomarkers biomarker NNS cord-285647-9tegcrc3 337 11 is be VBZ cord-285647-9tegcrc3 337 12 a a DT cord-285647-9tegcrc3 337 13 prominent prominent JJ cord-285647-9tegcrc3 337 14 feature feature NN cord-285647-9tegcrc3 337 15 of of IN cord-285647-9tegcrc3 337 16 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 337 17 , , , cord-285647-9tegcrc3 337 18 which which WDT cord-285647-9tegcrc3 337 19 in in IN cord-285647-9tegcrc3 337 20 general general JJ cord-285647-9tegcrc3 337 21 is be VBZ cord-285647-9tegcrc3 337 22 associated associate VBN cord-285647-9tegcrc3 337 23 with with IN cord-285647-9tegcrc3 337 24 a a DT cord-285647-9tegcrc3 337 25 worse bad JJR cord-285647-9tegcrc3 337 26 prognosis prognosis NN cord-285647-9tegcrc3 337 27 . . . cord-285647-9tegcrc3 338 1 53 53 CD cord-285647-9tegcrc3 339 1 Myocardial myocardial JJ cord-285647-9tegcrc3 339 2 damage damage NN cord-285647-9tegcrc3 339 3 and and CC cord-285647-9tegcrc3 339 4 heart heart NN cord-285647-9tegcrc3 339 5 failure failure NN cord-285647-9tegcrc3 339 6 are be VBP cord-285647-9tegcrc3 339 7 responsible responsible JJ cord-285647-9tegcrc3 339 8 for for IN cord-285647-9tegcrc3 339 9 40 40 CD cord-285647-9tegcrc3 339 10 % % NN cord-285647-9tegcrc3 339 11 of of IN cord-285647-9tegcrc3 339 12 death death NN cord-285647-9tegcrc3 339 13 in in IN cord-285647-9tegcrc3 339 14 the the DT cord-285647-9tegcrc3 339 15 Wuhan Wuhan NNP cord-285647-9tegcrc3 339 16 cohort cohort NN cord-285647-9tegcrc3 339 17 ( ( -LRB- cord-285647-9tegcrc3 339 18 see see VB cord-285647-9tegcrc3 339 19 references reference NNS cord-285647-9tegcrc3 339 20 in in IN cord-285647-9tegcrc3 339 21 Ref Ref NNP cord-285647-9tegcrc3 339 22 . . . cord-285647-9tegcrc3 339 23 53 53 CD cord-285647-9tegcrc3 339 24 ) ) -RRB- cord-285647-9tegcrc3 339 25 . . . cord-285647-9tegcrc3 340 1 Although although IN cord-285647-9tegcrc3 340 2 the the DT cord-285647-9tegcrc3 340 3 exact exact JJ cord-285647-9tegcrc3 340 4 mechanism mechanism NN cord-285647-9tegcrc3 340 5 involving involve VBG cord-285647-9tegcrc3 340 6 the the DT cord-285647-9tegcrc3 340 7 heart heart NN cord-285647-9tegcrc3 340 8 injury injury NN cord-285647-9tegcrc3 340 9 is be VBZ cord-285647-9tegcrc3 340 10 not not RB cord-285647-9tegcrc3 340 11 known know VBN cord-285647-9tegcrc3 340 12 , , , cord-285647-9tegcrc3 340 13 the the DT cord-285647-9tegcrc3 340 14 hypothesis hypothesis NN cord-285647-9tegcrc3 340 15 of of IN cord-285647-9tegcrc3 340 16 direct direct JJ cord-285647-9tegcrc3 340 17 myocardial myocardial JJ cord-285647-9tegcrc3 340 18 infection infection NN cord-285647-9tegcrc3 340 19 by by IN cord-285647-9tegcrc3 340 20 SARS SARS NNP cord-285647-9tegcrc3 340 21 - - HYPH cord-285647-9tegcrc3 340 22 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 340 23 is be VBZ cord-285647-9tegcrc3 340 24 a a DT cord-285647-9tegcrc3 340 25 possibility possibility NN cord-285647-9tegcrc3 340 26 , , , cord-285647-9tegcrc3 340 27 which which WDT cord-285647-9tegcrc3 340 28 acts act VBZ cord-285647-9tegcrc3 340 29 along along RB cord-285647-9tegcrc3 340 30 or or CC cord-285647-9tegcrc3 340 31 in in IN cord-285647-9tegcrc3 340 32 combination combination NN cord-285647-9tegcrc3 340 33 with with IN cord-285647-9tegcrc3 340 34 the the DT cord-285647-9tegcrc3 340 35 increased increase VBN cord-285647-9tegcrc3 340 36 cardiac cardiac JJ cord-285647-9tegcrc3 340 37 stress stress NN cord-285647-9tegcrc3 340 38 due due IN cord-285647-9tegcrc3 340 39 to to IN cord-285647-9tegcrc3 340 40 respiratory respiratory JJ cord-285647-9tegcrc3 340 41 failure failure NN cord-285647-9tegcrc3 340 42 and and CC cord-285647-9tegcrc3 340 43 hypoxemia hypoxemia NN cord-285647-9tegcrc3 340 44 , , , cord-285647-9tegcrc3 341 1 and/or and/or CC cord-285647-9tegcrc3 341 2 with with IN cord-285647-9tegcrc3 341 3 the the DT cord-285647-9tegcrc3 341 4 indirect indirect JJ cord-285647-9tegcrc3 341 5 injury injury NN cord-285647-9tegcrc3 341 6 from from IN cord-285647-9tegcrc3 341 7 the the DT cord-285647-9tegcrc3 341 8 systemic systemic JJ cord-285647-9tegcrc3 341 9 inflammatory inflammatory JJ cord-285647-9tegcrc3 341 10 response response NN cord-285647-9tegcrc3 341 11 . . . cord-285647-9tegcrc3 342 1 [ [ -LRB- cord-285647-9tegcrc3 342 2 53 53 CD cord-285647-9tegcrc3 342 3 ] ] -RRB- cord-285647-9tegcrc3 342 4 [ [ -LRB- cord-285647-9tegcrc3 342 5 54 54 CD cord-285647-9tegcrc3 342 6 ] ] -RRB- cord-285647-9tegcrc3 343 1 [ [ -LRB- cord-285647-9tegcrc3 343 2 55 55 CD cord-285647-9tegcrc3 343 3 ] ] -RRB- cord-285647-9tegcrc3 344 1 [ [ -LRB- cord-285647-9tegcrc3 344 2 56 56 CD cord-285647-9tegcrc3 344 3 ] ] -RRB- cord-285647-9tegcrc3 345 1 As as IN cord-285647-9tegcrc3 345 2 can can MD cord-285647-9tegcrc3 345 3 be be VB cord-285647-9tegcrc3 345 4 seen see VBN cord-285647-9tegcrc3 345 5 in in IN cord-285647-9tegcrc3 345 6 Table table NN cord-285647-9tegcrc3 346 1 I -PRON- PRP cord-285647-9tegcrc3 346 2 , , , cord-285647-9tegcrc3 346 3 the the DT cord-285647-9tegcrc3 346 4 testis testis NN cord-285647-9tegcrc3 346 5 is be VBZ cord-285647-9tegcrc3 346 6 the the DT cord-285647-9tegcrc3 346 7 tissue tissue NN cord-285647-9tegcrc3 346 8 where where WRB cord-285647-9tegcrc3 346 9 several several JJ cord-285647-9tegcrc3 346 10 of of IN cord-285647-9tegcrc3 346 11 the the DT cord-285647-9tegcrc3 346 12 proteins protein NNS cord-285647-9tegcrc3 346 13 targeted target VBN cord-285647-9tegcrc3 346 14 by by IN cord-285647-9tegcrc3 346 15 SARS SARS NNP cord-285647-9tegcrc3 346 16 - - HYPH cord-285647-9tegcrc3 346 17 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 346 18 are be VBP cord-285647-9tegcrc3 346 19 mainly mainly RB cord-285647-9tegcrc3 346 20 expressed express VBN cord-285647-9tegcrc3 346 21 , , , cord-285647-9tegcrc3 346 22 e.g. e.g. RB cord-285647-9tegcrc3 346 23 , , , cord-285647-9tegcrc3 346 24 CEP43 CEP43 NNP cord-285647-9tegcrc3 346 25 , , , cord-285647-9tegcrc3 346 26 TLE5 TLE5 NNP cord-285647-9tegcrc3 346 27 , , , cord-285647-9tegcrc3 346 28 PRIM2 PRIM2 NNP cord-285647-9tegcrc3 346 29 , , , cord-285647-9tegcrc3 346 30 MIPOL1 MIPOL1 NNS cord-285647-9tegcrc3 346 31 , , , cord-285647-9tegcrc3 346 32 REEP6 REEP6 NNS cord-285647-9tegcrc3 346 33 , , , cord-285647-9tegcrc3 346 34 HOOK1 hook1 NN cord-285647-9tegcrc3 346 35 , , , cord-285647-9tegcrc3 346 36 CENPF CENPF NNP cord-285647-9tegcrc3 346 37 , , , cord-285647-9tegcrc3 346 38 TRIM59 TRIM59 NNP cord-285647-9tegcrc3 346 39 , , , cord-285647-9tegcrc3 346 40 and and CC cord-285647-9tegcrc3 346 41 MARK1 mark1 NN cord-285647-9tegcrc3 346 42 . . . cord-285647-9tegcrc3 347 1 Currently currently RB cord-285647-9tegcrc3 347 2 , , , cord-285647-9tegcrc3 347 3 there there EX cord-285647-9tegcrc3 347 4 is be VBZ cord-285647-9tegcrc3 347 5 no no DT cord-285647-9tegcrc3 347 6 conclusive conclusive JJ cord-285647-9tegcrc3 347 7 evidence evidence NN cord-285647-9tegcrc3 347 8 about about IN cord-285647-9tegcrc3 347 9 the the DT cord-285647-9tegcrc3 347 10 testis testis NN cord-285647-9tegcrc3 347 11 damage damage NN cord-285647-9tegcrc3 347 12 by by IN cord-285647-9tegcrc3 347 13 SARS SARS NNP cord-285647-9tegcrc3 347 14 - - HYPH cord-285647-9tegcrc3 347 15 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 347 16 . . . cord-285647-9tegcrc3 348 1 57 57 CD cord-285647-9tegcrc3 348 2 - - SYM cord-285647-9tegcrc3 348 3 60 60 CD cord-285647-9tegcrc3 349 1 However however RB cord-285647-9tegcrc3 349 2 , , , cord-285647-9tegcrc3 349 3 the the DT cord-285647-9tegcrc3 349 4 previous previous JJ cord-285647-9tegcrc3 349 5 SARS SARS NNP cord-285647-9tegcrc3 349 6 - - HYPH cord-285647-9tegcrc3 349 7 CoV CoV NNP cord-285647-9tegcrc3 349 8 that that WDT cord-285647-9tegcrc3 349 9 appeared appear VBD cord-285647-9tegcrc3 349 10 in in IN cord-285647-9tegcrc3 349 11 2003 2003 CD cord-285647-9tegcrc3 349 12 and and CC cord-285647-9tegcrc3 349 13 which which WDT cord-285647-9tegcrc3 349 14 shares share VBZ cord-285647-9tegcrc3 349 15 82 82 CD cord-285647-9tegcrc3 349 16 % % NN cord-285647-9tegcrc3 349 17 of of IN cord-285647-9tegcrc3 349 18 proteins protein NNS cord-285647-9tegcrc3 349 19 with with IN cord-285647-9tegcrc3 349 20 the the DT cord-285647-9tegcrc3 349 21 current current JJ cord-285647-9tegcrc3 349 22 one one CD cord-285647-9tegcrc3 349 23 produced produce VBN cord-285647-9tegcrc3 349 24 testis testis NN cord-285647-9tegcrc3 349 25 damage damage NN cord-285647-9tegcrc3 349 26 and and CC cord-285647-9tegcrc3 349 27 spermatogenesis spermatogenesis NN cord-285647-9tegcrc3 349 28 , , , cord-285647-9tegcrc3 349 29 and and CC cord-285647-9tegcrc3 349 30 it -PRON- PRP cord-285647-9tegcrc3 349 31 was be VBD cord-285647-9tegcrc3 349 32 concluded conclude VBN cord-285647-9tegcrc3 349 33 that that IN cord-285647-9tegcrc3 349 34 orchitis orchitis NN cord-285647-9tegcrc3 349 35 was be VBD cord-285647-9tegcrc3 349 36 a a DT cord-285647-9tegcrc3 349 37 complication complication NN cord-285647-9tegcrc3 349 38 of of IN cord-285647-9tegcrc3 349 39 that that DT cord-285647-9tegcrc3 349 40 previous previous JJ cord-285647-9tegcrc3 349 41 SARS SARS NNP cord-285647-9tegcrc3 349 42 disease disease NN cord-285647-9tegcrc3 349 43 . . . cord-285647-9tegcrc3 350 1 57 57 CD cord-285647-9tegcrc3 351 1 We -PRON- PRP cord-285647-9tegcrc3 351 2 also also RB cord-285647-9tegcrc3 351 3 detect detect VBP cord-285647-9tegcrc3 351 4 a a DT cord-285647-9tegcrc3 351 5 few few JJ cord-285647-9tegcrc3 351 6 proteins protein NNS cord-285647-9tegcrc3 351 7 mainly mainly RB cord-285647-9tegcrc3 351 8 expressed express VBN cord-285647-9tegcrc3 351 9 in in IN cord-285647-9tegcrc3 351 10 different different JJ cord-285647-9tegcrc3 351 11 brain brain NN cord-285647-9tegcrc3 351 12 tissues tissue NNS cord-285647-9tegcrc3 351 13 , , , cord-285647-9tegcrc3 351 14 such such JJ cord-285647-9tegcrc3 351 15 as as IN cord-285647-9tegcrc3 351 16 CEP135 CEP135 NNP cord-285647-9tegcrc3 351 17 , , , cord-285647-9tegcrc3 351 18 PRIM2 PRIM2 NNP cord-285647-9tegcrc3 351 19 , , , cord-285647-9tegcrc3 351 20 TRIM59 TRIM59 NNP cord-285647-9tegcrc3 351 21 , , , cord-285647-9tegcrc3 351 22 and and CC cord-285647-9tegcrc3 351 23 MARK1 mark1 NN cord-285647-9tegcrc3 351 24 . . . cord-285647-9tegcrc3 352 1 The the DT cord-285647-9tegcrc3 352 2 implication implication NN cord-285647-9tegcrc3 352 3 of of IN cord-285647-9tegcrc3 352 4 SARS SARS NNP cord-285647-9tegcrc3 352 5 - - HYPH cord-285647-9tegcrc3 352 6 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 352 7 and and CC cord-285647-9tegcrc3 352 8 cerebrovascular cerebrovascular JJ cord-285647-9tegcrc3 352 9 diseases disease NNS cord-285647-9tegcrc3 352 10 has have VBZ cord-285647-9tegcrc3 352 11 been be VBN cord-285647-9tegcrc3 352 12 reported report VBN cord-285647-9tegcrc3 352 13 , , , cord-285647-9tegcrc3 352 14 including include VBG cord-285647-9tegcrc3 352 15 neurological neurological JJ cord-285647-9tegcrc3 352 16 manifestations manifestation NNS cord-285647-9tegcrc3 352 17 as as RB cord-285647-9tegcrc3 352 18 well well RB cord-285647-9tegcrc3 352 19 as as IN cord-285647-9tegcrc3 352 20 cerebrovascular cerebrovascular JJ cord-285647-9tegcrc3 352 21 disease disease NN cord-285647-9tegcrc3 352 22 , , , cord-285647-9tegcrc3 352 23 such such JJ cord-285647-9tegcrc3 352 24 as as IN cord-285647-9tegcrc3 352 25 ischemic ischemic JJ cord-285647-9tegcrc3 352 26 stroke stroke NN cord-285647-9tegcrc3 352 27 , , , cord-285647-9tegcrc3 352 28 cerebral cerebral JJ cord-285647-9tegcrc3 352 29 venous venous JJ cord-285647-9tegcrc3 352 30 thrombosis thrombosis NN cord-285647-9tegcrc3 352 31 , , , cord-285647-9tegcrc3 352 32 and and CC cord-285647-9tegcrc3 352 33 cerebral cerebral JJ cord-285647-9tegcrc3 352 34 hemorrhage hemorrhage NN cord-285647-9tegcrc3 352 35 . . . cord-285647-9tegcrc3 353 1 [ [ -LRB- cord-285647-9tegcrc3 353 2 61 61 CD cord-285647-9tegcrc3 353 3 ] ] -RRB- cord-285647-9tegcrc3 353 4 [ [ -LRB- cord-285647-9tegcrc3 353 5 62 62 CD cord-285647-9tegcrc3 353 6 ] ] -RRB- cord-285647-9tegcrc3 354 1 [ [ -LRB- cord-285647-9tegcrc3 354 2 63 63 CD cord-285647-9tegcrc3 354 3 ] ] -RRB- cord-285647-9tegcrc3 355 1 Kidney kidney NN cord-285647-9tegcrc3 355 2 damage damage NN cord-285647-9tegcrc3 355 3 in in IN cord-285647-9tegcrc3 355 4 SARS SARS NNP cord-285647-9tegcrc3 355 5 - - HYPH cord-285647-9tegcrc3 355 6 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 355 7 patients patient NNS cord-285647-9tegcrc3 355 8 has have VBZ cord-285647-9tegcrc3 355 9 been be VBN cord-285647-9tegcrc3 355 10 reported report VBN cord-285647-9tegcrc3 355 11 , , , cord-285647-9tegcrc3 355 12 64 64 CD cord-285647-9tegcrc3 355 13 - - SYM cord-285647-9tegcrc3 355 14 66 66 CD cord-285647-9tegcrc3 355 15 which which WDT cord-285647-9tegcrc3 355 16 includes include VBZ cord-285647-9tegcrc3 355 17 signs sign NNS cord-285647-9tegcrc3 355 18 of of IN cord-285647-9tegcrc3 355 19 kidney kidney NN cord-285647-9tegcrc3 355 20 dysfunctions dysfunction NNS cord-285647-9tegcrc3 355 21 , , , cord-285647-9tegcrc3 355 22 proteinuria proteinuria NN cord-285647-9tegcrc3 355 23 , , , cord-285647-9tegcrc3 355 24 hematuria hematuria NN cord-285647-9tegcrc3 355 25 , , , cord-285647-9tegcrc3 355 26 increased increase VBN cord-285647-9tegcrc3 355 27 levels level NNS cord-285647-9tegcrc3 355 28 of of IN cord-285647-9tegcrc3 355 29 blood blood NN cord-285647-9tegcrc3 355 30 urea urea NN cord-285647-9tegcrc3 355 31 nitrogen nitrogen NN cord-285647-9tegcrc3 355 32 , , , cord-285647-9tegcrc3 355 33 and and CC cord-285647-9tegcrc3 355 34 increased increase VBN cord-285647-9tegcrc3 355 35 levels level NNS cord-285647-9tegcrc3 355 36 of of IN cord-285647-9tegcrc3 355 37 serum serum NN cord-285647-9tegcrc3 355 38 creatinine creatinine NN cord-285647-9tegcrc3 355 39 . . . cord-285647-9tegcrc3 356 1 As as RB cord-285647-9tegcrc3 356 2 much much JJ cord-285647-9tegcrc3 356 3 as as IN cord-285647-9tegcrc3 356 4 25 25 CD cord-285647-9tegcrc3 356 5 % % NN cord-285647-9tegcrc3 356 6 of of IN cord-285647-9tegcrc3 356 7 an an DT cord-285647-9tegcrc3 356 8 acute acute JJ cord-285647-9tegcrc3 356 9 kidney kidney NN cord-285647-9tegcrc3 356 10 injury injury NN cord-285647-9tegcrc3 356 11 has have VBZ cord-285647-9tegcrc3 356 12 been be VBN cord-285647-9tegcrc3 356 13 reported report VBN cord-285647-9tegcrc3 356 14 in in IN cord-285647-9tegcrc3 356 15 the the DT cord-285647-9tegcrc3 356 16 clinical clinical JJ cord-285647-9tegcrc3 356 17 setting setting NN cord-285647-9tegcrc3 356 18 of of IN cord-285647-9tegcrc3 356 19 SARS SARS NNP cord-285647-9tegcrc3 356 20 - - HYPH cord-285647-9tegcrc3 356 21 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 356 22 patients patient NNS cord-285647-9tegcrc3 356 23 . . . cord-285647-9tegcrc3 357 1 One one CD cord-285647-9tegcrc3 357 2 of of IN cord-285647-9tegcrc3 357 3 the the DT cord-285647-9tegcrc3 357 4 potential potential JJ cord-285647-9tegcrc3 357 5 mechanisms mechanism NNS cord-285647-9tegcrc3 357 6 for for IN cord-285647-9tegcrc3 357 7 kidney kidney NN cord-285647-9tegcrc3 357 8 damage damage NN cord-285647-9tegcrc3 357 9 is be VBZ cord-285647-9tegcrc3 357 10 the the DT cord-285647-9tegcrc3 357 11 organ organ NN cord-285647-9tegcrc3 357 12 crosstalk crosstalk NN cord-285647-9tegcrc3 357 13 , , , cord-285647-9tegcrc3 357 14 64 64 CD cord-285647-9tegcrc3 357 15 as as IN cord-285647-9tegcrc3 357 16 can can MD cord-285647-9tegcrc3 357 17 be be VB cord-285647-9tegcrc3 357 18 the the DT cord-285647-9tegcrc3 357 19 mechanism mechanism NN cord-285647-9tegcrc3 357 20 of of IN cord-285647-9tegcrc3 357 21 diffusion diffusion NN cord-285647-9tegcrc3 357 22 from from IN cord-285647-9tegcrc3 357 23 proteins protein NNS cord-285647-9tegcrc3 357 24 in in IN cord-285647-9tegcrc3 357 25 the the DT cord-285647-9tegcrc3 357 26 lungs lung NNS cord-285647-9tegcrc3 357 27 to to IN cord-285647-9tegcrc3 357 28 proteins protein NNS cord-285647-9tegcrc3 357 29 in in IN cord-285647-9tegcrc3 357 30 the the DT cord-285647-9tegcrc3 357 31 urinary urinary JJ cord-285647-9tegcrc3 357 32 tract tract NN cord-285647-9tegcrc3 357 33 and and CC cord-285647-9tegcrc3 357 34 kidney kidney NN cord-285647-9tegcrc3 357 35 proposed propose VBN cord-285647-9tegcrc3 357 36 here here RB cord-285647-9tegcrc3 357 37 . . . cord-285647-9tegcrc3 358 1 A a DT cord-285647-9tegcrc3 358 2 very very RB cord-285647-9tegcrc3 358 3 interesting interesting JJ cord-285647-9tegcrc3 358 4 observation observation NN cord-285647-9tegcrc3 358 5 from from IN cord-285647-9tegcrc3 358 6 Table Table NNP cord-285647-9tegcrc3 359 1 I -PRON- PRP cord-285647-9tegcrc3 359 2 is be VBZ cord-285647-9tegcrc3 359 3 the the DT cord-285647-9tegcrc3 359 4 existence existence NN cord-285647-9tegcrc3 359 5 of of IN cord-285647-9tegcrc3 359 6 several several JJ cord-285647-9tegcrc3 359 7 proteins protein NNS cord-285647-9tegcrc3 359 8 expressed express VBN cord-285647-9tegcrc3 359 9 mainly mainly RB cord-285647-9tegcrc3 359 10 in in IN cord-285647-9tegcrc3 359 11 the the DT cord-285647-9tegcrc3 359 12 thymus thymus NN cord-285647-9tegcrc3 359 13 and and CC cord-285647-9tegcrc3 359 14 T t NN cord-285647-9tegcrc3 359 15 - - HYPH cord-285647-9tegcrc3 359 16 cells cell NNS cord-285647-9tegcrc3 359 17 , , , cord-285647-9tegcrc3 359 18 such such JJ cord-285647-9tegcrc3 359 19 as as IN cord-285647-9tegcrc3 359 20 TLE5 TLE5 NNP cord-285647-9tegcrc3 359 21 , , , cord-285647-9tegcrc3 359 22 RETREG3 RETREG3 NNS cord-285647-9tegcrc3 359 23 , , , cord-285647-9tegcrc3 359 24 RBM41 RBM41 NNP cord-285647-9tegcrc3 359 25 , , , cord-285647-9tegcrc3 359 26 CENPF CENPF NNP cord-285647-9tegcrc3 359 27 , , , cord-285647-9tegcrc3 359 28 and and CC cord-285647-9tegcrc3 359 29 TRIM59 TRIM59 NNP cord-285647-9tegcrc3 359 30 . . . cord-285647-9tegcrc3 360 1 It -PRON- PRP cord-285647-9tegcrc3 360 2 has have VBZ cord-285647-9tegcrc3 360 3 been be VBN cord-285647-9tegcrc3 360 4 reported report VBN cord-285647-9tegcrc3 360 5 that that IN cord-285647-9tegcrc3 360 6 many many JJ cord-285647-9tegcrc3 360 7 of of IN cord-285647-9tegcrc3 360 8 the the DT cord-285647-9tegcrc3 360 9 patients patient NNS cord-285647-9tegcrc3 360 10 affected affect VBN cord-285647-9tegcrc3 360 11 by by IN cord-285647-9tegcrc3 360 12 SARS SARS NNP cord-285647-9tegcrc3 360 13 - - HYPH cord-285647-9tegcrc3 360 14 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 360 15 in in IN cord-285647-9tegcrc3 360 16 Wuhan Wuhan NNP cord-285647-9tegcrc3 360 17 displayed display VBD cord-285647-9tegcrc3 360 18 a a DT cord-285647-9tegcrc3 360 19 significant significant JJ cord-285647-9tegcrc3 360 20 decrease decrease NN cord-285647-9tegcrc3 360 21 of of IN cord-285647-9tegcrc3 360 22 T t NN cord-285647-9tegcrc3 360 23 - - HYPH cord-285647-9tegcrc3 360 24 cells cell NNS cord-285647-9tegcrc3 360 25 . . . cord-285647-9tegcrc3 361 1 67 67 CD cord-285647-9tegcrc3 361 2 Thymus thymus NN cord-285647-9tegcrc3 361 3 is be VBZ cord-285647-9tegcrc3 361 4 an an DT cord-285647-9tegcrc3 361 5 organ organ NN cord-285647-9tegcrc3 361 6 that that WDT cord-285647-9tegcrc3 361 7 displays display VBZ cord-285647-9tegcrc3 361 8 a a DT cord-285647-9tegcrc3 361 9 progressive progressive JJ cord-285647-9tegcrc3 361 10 decline decline NN cord-285647-9tegcrc3 361 11 with with IN cord-285647-9tegcrc3 361 12 age age NN cord-285647-9tegcrc3 361 13 with with IN cord-285647-9tegcrc3 361 14 reduction reduction NN cord-285647-9tegcrc3 361 15 of of IN cord-285647-9tegcrc3 361 16 the the DT cord-285647-9tegcrc3 361 17 order order NN cord-285647-9tegcrc3 361 18 of of IN cord-285647-9tegcrc3 361 19 3%-5 3%-5 CD cord-285647-9tegcrc3 361 20 % % NN cord-285647-9tegcrc3 361 21 a a DT cord-285647-9tegcrc3 361 22 year year NN cord-285647-9tegcrc3 361 23 until until IN cord-285647-9tegcrc3 361 24 approximately approximately RB cord-285647-9tegcrc3 361 25 30 30 CD cord-285647-9tegcrc3 361 26 - - SYM cord-285647-9tegcrc3 361 27 40 40 CD cord-285647-9tegcrc3 361 28 years year NNS cord-285647-9tegcrc3 361 29 of of IN cord-285647-9tegcrc3 361 30 age age NN cord-285647-9tegcrc3 361 31 and and CC cord-285647-9tegcrc3 361 32 of of IN cord-285647-9tegcrc3 361 33 about about RB cord-285647-9tegcrc3 361 34 1 1 CD cord-285647-9tegcrc3 361 35 % % NN cord-285647-9tegcrc3 361 36 per per IN cord-285647-9tegcrc3 361 37 year year NN cord-285647-9tegcrc3 361 38 after after IN cord-285647-9tegcrc3 361 39 that that DT cord-285647-9tegcrc3 361 40 age age NN cord-285647-9tegcrc3 361 41 . . . cord-285647-9tegcrc3 362 1 Consequently consequently RB cord-285647-9tegcrc3 362 2 , , , cord-285647-9tegcrc3 362 3 it -PRON- PRP cord-285647-9tegcrc3 362 4 was be VBD cord-285647-9tegcrc3 362 5 proposed propose VBN cord-285647-9tegcrc3 362 6 that that IN cord-285647-9tegcrc3 362 7 the the DT cord-285647-9tegcrc3 362 8 role role NN cord-285647-9tegcrc3 362 9 of of IN cord-285647-9tegcrc3 362 10 thymus thymus NN cord-285647-9tegcrc3 362 11 should should MD cord-285647-9tegcrc3 362 12 be be VB cord-285647-9tegcrc3 362 13 taken take VBN cord-285647-9tegcrc3 362 14 into into IN cord-285647-9tegcrc3 362 15 account account NN cord-285647-9tegcrc3 362 16 in in IN cord-285647-9tegcrc3 362 17 order order NN cord-285647-9tegcrc3 362 18 to to TO cord-285647-9tegcrc3 362 19 explain explain VB cord-285647-9tegcrc3 362 20 why why WRB cord-285647-9tegcrc3 362 21 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 362 22 appears appear VBZ cord-285647-9tegcrc3 362 23 to to TO cord-285647-9tegcrc3 362 24 be be VB cord-285647-9tegcrc3 362 25 so so RB cord-285647-9tegcrc3 362 26 mild mild JJ cord-285647-9tegcrc3 362 27 in in IN cord-285647-9tegcrc3 362 28 children child NNS cord-285647-9tegcrc3 362 29 . . . cord-285647-9tegcrc3 363 1 67 67 CD cord-285647-9tegcrc3 364 1 The the DT cord-285647-9tegcrc3 364 2 protein protein NN cord-285647-9tegcrc3 364 3 TLE5 TLE5 NNP cord-285647-9tegcrc3 364 4 is be VBZ cord-285647-9tegcrc3 364 5 also also RB cord-285647-9tegcrc3 364 6 expressed express VBN cord-285647-9tegcrc3 364 7 significantly significantly RB cord-285647-9tegcrc3 364 8 in in IN cord-285647-9tegcrc3 364 9 the the DT cord-285647-9tegcrc3 364 10 lymph lymph NN cord-285647-9tegcrc3 364 11 nodes node NNS cord-285647-9tegcrc3 364 12 . . . cord-285647-9tegcrc3 365 1 It -PRON- PRP cord-285647-9tegcrc3 365 2 was be VBD cord-285647-9tegcrc3 365 3 found find VBN cord-285647-9tegcrc3 365 4 by by IN cord-285647-9tegcrc3 365 5 Feng Feng NNP cord-285647-9tegcrc3 365 6 et et FW cord-285647-9tegcrc3 365 7 al al NNP cord-285647-9tegcrc3 365 8 . . . cord-285647-9tegcrc3 366 1 68 68 CD cord-285647-9tegcrc3 367 1 that that IN cord-285647-9tegcrc3 367 2 SARS SARS NNP cord-285647-9tegcrc3 367 3 - - HYPH cord-285647-9tegcrc3 367 4 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 367 5 induces induce VBZ cord-285647-9tegcrc3 367 6 lymph lymph NN cord-285647-9tegcrc3 367 7 follicle follicle NN cord-285647-9tegcrc3 367 8 depletion depletion NN cord-285647-9tegcrc3 367 9 , , , cord-285647-9tegcrc3 367 10 splenic splenic JJ cord-285647-9tegcrc3 367 11 nodule nodule NN cord-285647-9tegcrc3 367 12 atrophy atrophy NN cord-285647-9tegcrc3 367 13 , , , cord-285647-9tegcrc3 367 14 histiocyte histiocyte NNP cord-285647-9tegcrc3 367 15 hyperplasia hyperplasia NN cord-285647-9tegcrc3 367 16 , , , cord-285647-9tegcrc3 367 17 and and CC cord-285647-9tegcrc3 367 18 lymphocyte lymphocyte NN cord-285647-9tegcrc3 367 19 reductions reduction NNS cord-285647-9tegcrc3 367 20 . . . cord-285647-9tegcrc3 368 1 The the DT cord-285647-9tegcrc3 368 2 proteins protein NNS cord-285647-9tegcrc3 368 3 HOOK1 hook1 RB cord-285647-9tegcrc3 369 1 and and CC cord-285647-9tegcrc3 369 2 MIPOL1 MIPOL1 NNS cord-285647-9tegcrc3 369 3 are be VBP cord-285647-9tegcrc3 369 4 significantly significantly RB cord-285647-9tegcrc3 369 5 expressed express VBN cord-285647-9tegcrc3 369 6 in in IN cord-285647-9tegcrc3 369 7 the the DT cord-285647-9tegcrc3 369 8 pituitary pituitary JJ cord-285647-9tegcrc3 369 9 gland gland NN cord-285647-9tegcrc3 369 10 . . . cord-285647-9tegcrc3 370 1 There there EX cord-285647-9tegcrc3 370 2 has have VBZ cord-285647-9tegcrc3 370 3 been be VBN cord-285647-9tegcrc3 370 4 some some DT cord-285647-9tegcrc3 370 5 evidence evidence NN cord-285647-9tegcrc3 370 6 and and CC cord-285647-9tegcrc3 370 7 concerns concern NNS cord-285647-9tegcrc3 370 8 that that IN cord-285647-9tegcrc3 370 9 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 370 10 may may MD cord-285647-9tegcrc3 370 11 also also RB cord-285647-9tegcrc3 370 12 damage damage VB cord-285647-9tegcrc3 370 13 the the DT cord-285647-9tegcrc3 370 14 hypothalamo hypothalamo JJ cord-285647-9tegcrc3 370 15 - - HYPH cord-285647-9tegcrc3 370 16 pituitary pituitary NN cord-285647-9tegcrc3 370 17 - - HYPH cord-285647-9tegcrc3 370 18 adrenal adrenal NN cord-285647-9tegcrc3 370 19 axis axis NN cord-285647-9tegcrc3 370 20 that that WDT cord-285647-9tegcrc3 370 21 has have VBZ cord-285647-9tegcrc3 370 22 been be VBN cord-285647-9tegcrc3 370 23 expressed express VBN cord-285647-9tegcrc3 370 24 by by IN cord-285647-9tegcrc3 370 25 Pal Pal NNP cord-285647-9tegcrc3 370 26 , , , cord-285647-9tegcrc3 370 27 69 69 CD cord-285647-9tegcrc3 370 28 which which WDT cord-285647-9tegcrc3 370 29 may may MD cord-285647-9tegcrc3 370 30 be be VB cord-285647-9tegcrc3 370 31 connected connect VBN cord-285647-9tegcrc3 370 32 with with IN cord-285647-9tegcrc3 370 33 the the DT cord-285647-9tegcrc3 370 34 participation participation NN cord-285647-9tegcrc3 370 35 of of IN cord-285647-9tegcrc3 370 36 the the DT cord-285647-9tegcrc3 370 37 previously previously RB cord-285647-9tegcrc3 370 38 mentioned mention VBN cord-285647-9tegcrc3 370 39 proteins protein NNS cord-285647-9tegcrc3 370 40 . . . cord-285647-9tegcrc3 371 1 Another another DT cord-285647-9tegcrc3 371 2 surprising surprising JJ cord-285647-9tegcrc3 371 3 finding finding NN cord-285647-9tegcrc3 371 4 of of IN cord-285647-9tegcrc3 371 5 the the DT cord-285647-9tegcrc3 371 6 current current JJ cord-285647-9tegcrc3 371 7 work work NN cord-285647-9tegcrc3 371 8 is be VBZ cord-285647-9tegcrc3 371 9 the the DT cord-285647-9tegcrc3 371 10 elevated elevated JJ cord-285647-9tegcrc3 371 11 number number NN cord-285647-9tegcrc3 371 12 of of IN cord-285647-9tegcrc3 371 13 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 371 14 shortest short JJS cord-285647-9tegcrc3 371 15 paths path NNS cord-285647-9tegcrc3 371 16 that that WDT cord-285647-9tegcrc3 371 17 coincide coincide VBP cord-285647-9tegcrc3 371 18 with with IN cord-285647-9tegcrc3 371 19 the the DT cord-285647-9tegcrc3 371 20 shortest short JJS cord-285647-9tegcrc3 371 21 ( ( -LRB- cord-285647-9tegcrc3 371 22 topological topological JJ cord-285647-9tegcrc3 371 23 ) ) -RRB- cord-285647-9tegcrc3 371 24 paths path NNS cord-285647-9tegcrc3 371 25 connecting connect VBG cord-285647-9tegcrc3 371 26 pairs pair NNS cord-285647-9tegcrc3 371 27 of of IN cord-285647-9tegcrc3 371 28 proteins protein NNS cord-285647-9tegcrc3 371 29 in in IN cord-285647-9tegcrc3 371 30 the the DT cord-285647-9tegcrc3 371 31 PPI PPI NNP cord-285647-9tegcrc3 371 32 of of IN cord-285647-9tegcrc3 371 33 human human JJ cord-285647-9tegcrc3 371 34 proteins protein NNS cord-285647-9tegcrc3 371 35 targeted target VBN cord-285647-9tegcrc3 371 36 by by IN cord-285647-9tegcrc3 371 37 SARS SARS NNP cord-285647-9tegcrc3 371 38 - - HYPH cord-285647-9tegcrc3 371 39 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 371 40 . . . cord-285647-9tegcrc3 372 1 This this DT cord-285647-9tegcrc3 372 2 means mean VBZ cord-285647-9tegcrc3 372 3 that that IN cord-285647-9tegcrc3 372 4 the the DT cord-285647-9tegcrc3 372 5 efficiency efficiency NN cord-285647-9tegcrc3 372 6 of of IN cord-285647-9tegcrc3 372 7 the the DT cord-285647-9tegcrc3 372 8 diffusive diffusive JJ cord-285647-9tegcrc3 372 9 paths path NNS cord-285647-9tegcrc3 372 10 connecting connect VBG cord-285647-9tegcrc3 372 11 pairs pair NNS cord-285647-9tegcrc3 372 12 of of IN cord-285647-9tegcrc3 372 13 nodes node NNS cord-285647-9tegcrc3 372 14 in in IN cord-285647-9tegcrc3 372 15 this this DT cord-285647-9tegcrc3 372 16 PPI PPI NNP cord-285647-9tegcrc3 372 17 is be VBZ cord-285647-9tegcrc3 372 18 almost almost RB cord-285647-9tegcrc3 372 19 98 98 CD cord-285647-9tegcrc3 372 20 % % NN cord-285647-9tegcrc3 372 21 in in IN cord-285647-9tegcrc3 372 22 relation relation NN cord-285647-9tegcrc3 372 23 to to IN cord-285647-9tegcrc3 372 24 a a DT cord-285647-9tegcrc3 372 25 hypothetical hypothetical JJ cord-285647-9tegcrc3 372 26 process process NN cord-285647-9tegcrc3 372 27 that that WDT cord-285647-9tegcrc3 372 28 uses use VBZ cord-285647-9tegcrc3 372 29 the the DT cord-285647-9tegcrc3 372 30 shortest short JJS cord-285647-9tegcrc3 372 31 ( ( -LRB- cord-285647-9tegcrc3 372 32 topological topological JJ cord-285647-9tegcrc3 372 33 ) ) -RRB- cord-285647-9tegcrc3 372 34 paths path NNS cord-285647-9tegcrc3 372 35 in in IN cord-285647-9tegcrc3 372 36 propagating propagate VBG cord-285647-9tegcrc3 372 37 perturbations perturbation NNS cord-285647-9tegcrc3 372 38 between between IN cord-285647-9tegcrc3 372 39 pairs pair NNS cord-285647-9tegcrc3 372 40 of of IN cord-285647-9tegcrc3 372 41 proteins protein NNS cord-285647-9tegcrc3 372 42 . . . cord-285647-9tegcrc3 373 1 The the DT cord-285647-9tegcrc3 373 2 437 437 CD cord-285647-9tegcrc3 373 3 shortest short JJS cord-285647-9tegcrc3 373 4 diffusive diffusive JJ cord-285647-9tegcrc3 373 5 paths path NNS cord-285647-9tegcrc3 373 6 reported report VBN cord-285647-9tegcrc3 373 7 here here RB cord-285647-9tegcrc3 373 8 contain contain VBP cord-285647-9tegcrc3 373 9 one one CD cord-285647-9tegcrc3 373 10 more more JJR cord-285647-9tegcrc3 373 11 edge edge NN cord-285647-9tegcrc3 373 12 than than IN cord-285647-9tegcrc3 373 13 the the DT cord-285647-9tegcrc3 373 14 corresponding correspond VBG cord-285647-9tegcrc3 373 15 shortest short JJS cord-285647-9tegcrc3 373 16 ( ( -LRB- cord-285647-9tegcrc3 373 17 topological topological JJ cord-285647-9tegcrc3 373 18 ) ) -RRB- cord-285647-9tegcrc3 373 19 paths path NNS cord-285647-9tegcrc3 373 20 . . . cord-285647-9tegcrc3 374 1 The the DT cord-285647-9tegcrc3 374 2 proteins protein NNS cord-285647-9tegcrc3 374 3 appearing appear VBG cord-285647-9tegcrc3 374 4 in in IN cord-285647-9tegcrc3 374 5 these these DT cord-285647-9tegcrc3 374 6 paths path NNS cord-285647-9tegcrc3 374 7 would would MD cord-285647-9tegcrc3 374 8 never never RB cord-285647-9tegcrc3 374 9 be be VB cord-285647-9tegcrc3 374 10 visited visit VBN cord-285647-9tegcrc3 374 11 in in IN cord-285647-9tegcrc3 374 12 the the DT cord-285647-9tegcrc3 374 13 paths path NNS cord-285647-9tegcrc3 374 14 connecting connect VBG cord-285647-9tegcrc3 374 15 two two CD cord-285647-9tegcrc3 374 16 other other JJ cord-285647-9tegcrc3 374 17 proteins protein NNS cord-285647-9tegcrc3 374 18 if if IN cord-285647-9tegcrc3 374 19 only only RB cord-285647-9tegcrc3 374 20 the the DT cord-285647-9tegcrc3 374 21 shortest short JJS cord-285647-9tegcrc3 374 22 ( ( -LRB- cord-285647-9tegcrc3 374 23 topological topological JJ cord-285647-9tegcrc3 374 24 ) ) -RRB- cord-285647-9tegcrc3 374 25 paths path NNS cord-285647-9tegcrc3 374 26 were be VBD cord-285647-9tegcrc3 374 27 used use VBN cord-285647-9tegcrc3 374 28 . . . cord-285647-9tegcrc3 375 1 What what WP cord-285647-9tegcrc3 375 2 is be VBZ cord-285647-9tegcrc3 375 3 interesting interesting JJ cord-285647-9tegcrc3 375 4 to to TO cord-285647-9tegcrc3 375 5 note note VB cord-285647-9tegcrc3 375 6 that that IN cord-285647-9tegcrc3 375 7 6 6 CD cord-285647-9tegcrc3 375 8 out out IN cord-285647-9tegcrc3 375 9 of of IN cord-285647-9tegcrc3 375 10 the the DT cord-285647-9tegcrc3 375 11 15 15 CD cord-285647-9tegcrc3 375 12 proteins protein NNS cord-285647-9tegcrc3 375 13 that that WDT cord-285647-9tegcrc3 375 14 are be VBP cord-285647-9tegcrc3 375 15 mainly mainly RB cord-285647-9tegcrc3 375 16 expressed express VBN cord-285647-9tegcrc3 375 17 outside outside IN cord-285647-9tegcrc3 375 18 the the DT cord-285647-9tegcrc3 375 19 lungs lung NNS cord-285647-9tegcrc3 375 20 are be VBP cord-285647-9tegcrc3 375 21 among among IN cord-285647-9tegcrc3 375 22 the the DT cord-285647-9tegcrc3 375 23 ones one NNS cord-285647-9tegcrc3 375 24 " " `` cord-285647-9tegcrc3 375 25 crossed cross VBD cord-285647-9tegcrc3 375 26 " " '' cord-285647-9tegcrc3 375 27 by by IN cord-285647-9tegcrc3 375 28 these these DT cord-285647-9tegcrc3 375 29 paths path NNS cord-285647-9tegcrc3 375 30 . . . cord-285647-9tegcrc3 376 1 They -PRON- PRP cord-285647-9tegcrc3 376 2 are be VBP cord-285647-9tegcrc3 376 3 TLE5 TLE5 NNP cord-285647-9tegcrc3 376 4 ( ( -LRB- cord-285647-9tegcrc3 376 5 thymus thymus NN cord-285647-9tegcrc3 376 6 , , , cord-285647-9tegcrc3 376 7 lymph lymph NN cord-285647-9tegcrc3 376 8 node node NN cord-285647-9tegcrc3 376 9 , , , cord-285647-9tegcrc3 376 10 testis testis NN cord-285647-9tegcrc3 376 11 ) ) -RRB- cord-285647-9tegcrc3 376 12 , , , cord-285647-9tegcrc3 376 13 PKP2 PKP2 NNP cord-285647-9tegcrc3 376 14 ( ( -LRB- cord-285647-9tegcrc3 376 15 heart heart NN cord-285647-9tegcrc3 376 16 muscle muscle NN cord-285647-9tegcrc3 376 17 ) ) -RRB- cord-285647-9tegcrc3 376 18 , , , cord-285647-9tegcrc3 376 19 CEP135 CEP135 NNP cord-285647-9tegcrc3 376 20 ( ( -LRB- cord-285647-9tegcrc3 376 21 skeletal skeletal JJ cord-285647-9tegcrc3 376 22 muscle muscle NN cord-285647-9tegcrc3 376 23 , , , cord-285647-9tegcrc3 376 24 heart heart NN cord-285647-9tegcrc3 376 25 muscle muscle NN cord-285647-9tegcrc3 376 26 , , , cord-285647-9tegcrc3 376 27 cerebral cerebral JJ cord-285647-9tegcrc3 376 28 cortex cortex NN cord-285647-9tegcrc3 376 29 , , , cord-285647-9tegcrc3 376 30 cerebellum cerebellum NN cord-285647-9tegcrc3 376 31 ) ) -RRB- cord-285647-9tegcrc3 376 32 , , , cord-285647-9tegcrc3 376 33 CEP43 CEP43 NNP cord-285647-9tegcrc3 376 34 ( ( -LRB- cord-285647-9tegcrc3 376 35 testis testis NN cord-285647-9tegcrc3 376 36 ) ) -RRB- cord-285647-9tegcrc3 376 37 , , , cord-285647-9tegcrc3 376 38 RBM41 rbm41 FW cord-285647-9tegcrc3 376 39 ( ( -LRB- cord-285647-9tegcrc3 376 40 pancreas pancreas NN cord-285647-9tegcrc3 376 41 , , , cord-285647-9tegcrc3 376 42 T t NN cord-285647-9tegcrc3 376 43 - - HYPH cord-285647-9tegcrc3 376 44 cells cell NNS cord-285647-9tegcrc3 376 45 , , , cord-285647-9tegcrc3 376 46 testis testis NN cord-285647-9tegcrc3 376 47 , , , cord-285647-9tegcrc3 376 48 retina retina NN cord-285647-9tegcrc3 376 49 ) ) -RRB- cord-285647-9tegcrc3 376 50 , , , cord-285647-9tegcrc3 376 51 and and CC cord-285647-9tegcrc3 376 52 RETREG3 RETREG3 NNP cord-285647-9tegcrc3 376 53 ( ( -LRB- cord-285647-9tegcrc3 376 54 prostate prostate NN cord-285647-9tegcrc3 376 55 , , , cord-285647-9tegcrc3 376 56 thymus thymus NN cord-285647-9tegcrc3 376 57 ) ) -RRB- cord-285647-9tegcrc3 376 58 . . . cord-285647-9tegcrc3 377 1 This this DT cord-285647-9tegcrc3 377 2 means mean VBZ cord-285647-9tegcrc3 377 3 that that IN cord-285647-9tegcrc3 377 4 the the DT cord-285647-9tegcrc3 377 5 perturbation perturbation NN cord-285647-9tegcrc3 377 6 of of IN cord-285647-9tegcrc3 377 7 these these DT cord-285647-9tegcrc3 377 8 proteins protein NNS cord-285647-9tegcrc3 377 9 occurs occur VBZ cord-285647-9tegcrc3 377 10 not not RB cord-285647-9tegcrc3 377 11 only only RB cord-285647-9tegcrc3 377 12 through through IN cord-285647-9tegcrc3 377 13 the the DT cord-285647-9tegcrc3 377 14 diffusion diffusion NN cord-285647-9tegcrc3 377 15 from from IN cord-285647-9tegcrc3 377 16 other other JJ cord-285647-9tegcrc3 377 17 proteins protein NNS cord-285647-9tegcrc3 377 18 in in IN cord-285647-9tegcrc3 377 19 the the DT cord-285647-9tegcrc3 377 20 lungs lung NNS cord-285647-9tegcrc3 377 21 directly directly RB cord-285647-9tegcrc3 377 22 to to IN cord-285647-9tegcrc3 377 23 them -PRON- PRP cord-285647-9tegcrc3 377 24 , , , cord-285647-9tegcrc3 377 25 but but CC cord-285647-9tegcrc3 377 26 also also RB cord-285647-9tegcrc3 377 27 through through IN cord-285647-9tegcrc3 377 28 some some DT cord-285647-9tegcrc3 377 29 " " `` cord-285647-9tegcrc3 377 30 accidental accidental JJ cord-285647-9tegcrc3 377 31 " " '' cord-285647-9tegcrc3 377 32 diffusive diffusive JJ cord-285647-9tegcrc3 377 33 paths path NNS cord-285647-9tegcrc3 377 34 between between IN cord-285647-9tegcrc3 377 35 pairs pair NNS cord-285647-9tegcrc3 377 36 of of IN cord-285647-9tegcrc3 377 37 proteins protein NNS cord-285647-9tegcrc3 377 38 that that WDT cord-285647-9tegcrc3 377 39 are be VBP cord-285647-9tegcrc3 377 40 both both DT cord-285647-9tegcrc3 377 41 located locate VBN cord-285647-9tegcrc3 377 42 in in IN cord-285647-9tegcrc3 377 43 the the DT cord-285647-9tegcrc3 377 44 lungs lung NNS cord-285647-9tegcrc3 377 45 . . . cord-285647-9tegcrc3 378 1 All all RB cord-285647-9tegcrc3 378 2 in in IN cord-285647-9tegcrc3 378 3 all all DT cord-285647-9tegcrc3 378 4 , , , cord-285647-9tegcrc3 378 5 the the DT cord-285647-9tegcrc3 378 6 use use NN cord-285647-9tegcrc3 378 7 of of IN cord-285647-9tegcrc3 378 8 time time NN cord-285647-9tegcrc3 378 9 - - HYPH cord-285647-9tegcrc3 378 10 fractional fractional JJ cord-285647-9tegcrc3 378 11 diffusive diffusive JJ cord-285647-9tegcrc3 378 12 models model NNS cord-285647-9tegcrc3 378 13 to to TO cord-285647-9tegcrc3 378 14 study study VB cord-285647-9tegcrc3 378 15 the the DT cord-285647-9tegcrc3 378 16 propagation propagation NN cord-285647-9tegcrc3 378 17 of of IN cord-285647-9tegcrc3 378 18 perturbations perturbation NNS cord-285647-9tegcrc3 378 19 on on IN cord-285647-9tegcrc3 378 20 PPI PPI NNP cord-285647-9tegcrc3 378 21 networks network NNS cord-285647-9tegcrc3 378 22 seems seem VBZ cord-285647-9tegcrc3 378 23 a a DT cord-285647-9tegcrc3 378 24 very very RB cord-285647-9tegcrc3 378 25 promising promising JJ cord-285647-9tegcrc3 378 26 approach approach NN cord-285647-9tegcrc3 378 27 . . . cord-285647-9tegcrc3 379 1 The the DT cord-285647-9tegcrc3 379 2 model model NN cord-285647-9tegcrc3 379 3 is be VBZ cord-285647-9tegcrc3 379 4 not not RB cord-285647-9tegcrc3 379 5 only only RB cord-285647-9tegcrc3 379 6 biologically biologically RB cord-285647-9tegcrc3 379 7 sounded sounded JJ cord-285647-9tegcrc3 379 8 but but CC cord-285647-9tegcrc3 379 9 it -PRON- PRP cord-285647-9tegcrc3 379 10 also also RB cord-285647-9tegcrc3 379 11 allows allow VBZ cord-285647-9tegcrc3 379 12 us -PRON- PRP cord-285647-9tegcrc3 379 13 to to TO cord-285647-9tegcrc3 379 14 discover discover VB cord-285647-9tegcrc3 379 15 interesting interesting JJ cord-285647-9tegcrc3 379 16 hidden hidden JJ cord-285647-9tegcrc3 379 17 patterns pattern NNS cord-285647-9tegcrc3 379 18 of of IN cord-285647-9tegcrc3 379 19 the the DT cord-285647-9tegcrc3 379 20 Chaos Chaos NNP cord-285647-9tegcrc3 379 21 ARTICLE article NN cord-285647-9tegcrc3 379 22 scitation.org/journal/cha scitation.org/journal/cha WRB cord-285647-9tegcrc3 379 23 interactions interaction NNS cord-285647-9tegcrc3 379 24 between between IN cord-285647-9tegcrc3 379 25 proteins protein NNS cord-285647-9tegcrc3 379 26 and and CC cord-285647-9tegcrc3 379 27 the the DT cord-285647-9tegcrc3 379 28 propagation propagation NN cord-285647-9tegcrc3 379 29 of of IN cord-285647-9tegcrc3 379 30 perturbations perturbation NNS cord-285647-9tegcrc3 379 31 among among IN cord-285647-9tegcrc3 379 32 them -PRON- PRP cord-285647-9tegcrc3 379 33 . . . cord-285647-9tegcrc3 380 1 In in IN cord-285647-9tegcrc3 380 2 the the DT cord-285647-9tegcrc3 380 3 case case NN cord-285647-9tegcrc3 380 4 of of IN cord-285647-9tegcrc3 380 5 the the DT cord-285647-9tegcrc3 380 6 PIN pin NN cord-285647-9tegcrc3 380 7 of of IN cord-285647-9tegcrc3 380 8 human human JJ cord-285647-9tegcrc3 380 9 proteins protein NNS cord-285647-9tegcrc3 380 10 targeted target VBN cord-285647-9tegcrc3 380 11 by by IN cord-285647-9tegcrc3 380 12 SARS SARS NNP cord-285647-9tegcrc3 380 13 - - HYPH cord-285647-9tegcrc3 380 14 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 380 15 , , , cord-285647-9tegcrc3 380 16 our -PRON- PRP$ cord-285647-9tegcrc3 380 17 current current JJ cord-285647-9tegcrc3 380 18 finding finding NN cord-285647-9tegcrc3 380 19 may may MD cord-285647-9tegcrc3 380 20 help help VB cord-285647-9tegcrc3 380 21 to to TO cord-285647-9tegcrc3 380 22 understand understand VB cord-285647-9tegcrc3 380 23 potential potential JJ cord-285647-9tegcrc3 380 24 molecular molecular JJ cord-285647-9tegcrc3 380 25 mechanisms mechanism NNS cord-285647-9tegcrc3 380 26 for for IN cord-285647-9tegcrc3 380 27 the the DT cord-285647-9tegcrc3 380 28 multi multi JJ cord-285647-9tegcrc3 380 29 - - NNS cord-285647-9tegcrc3 380 30 organs organ NNS cord-285647-9tegcrc3 380 31 and and CC cord-285647-9tegcrc3 380 32 systemic systemic JJ cord-285647-9tegcrc3 380 33 failures failure NNS cord-285647-9tegcrc3 380 34 occurring occur VBG cord-285647-9tegcrc3 380 35 in in IN cord-285647-9tegcrc3 380 36 many many JJ cord-285647-9tegcrc3 380 37 patients patient NNS cord-285647-9tegcrc3 380 38 . . . cord-285647-9tegcrc3 381 1 After after IN cord-285647-9tegcrc3 381 2 this this DT cord-285647-9tegcrc3 381 3 work work NN cord-285647-9tegcrc3 381 4 was be VBD cord-285647-9tegcrc3 381 5 completed complete VBN cord-285647-9tegcrc3 381 6 , , , cord-285647-9tegcrc3 381 7 Qiu Qiu NNP cord-285647-9tegcrc3 381 8 et et FW cord-285647-9tegcrc3 381 9 al al NNP cord-285647-9tegcrc3 381 10 . . . cord-285647-9tegcrc3 381 11 75 75 CD cord-285647-9tegcrc3 381 12 uploaded upload VBD cord-285647-9tegcrc3 381 13 the the DT cord-285647-9tegcrc3 381 14 manuscript manuscript NN cord-285647-9tegcrc3 381 15 entitled entitle VBN cord-285647-9tegcrc3 381 16 " " `` cord-285647-9tegcrc3 381 17 Postmortem postmortem JJ cord-285647-9tegcrc3 381 18 tissue tissue NN cord-285647-9tegcrc3 381 19 proteomics proteomic NNS cord-285647-9tegcrc3 381 20 reveals reveal VBZ cord-285647-9tegcrc3 381 21 the the DT cord-285647-9tegcrc3 381 22 pathogenesis pathogenesis NN cord-285647-9tegcrc3 381 23 of of IN cord-285647-9tegcrc3 381 24 multiorgan multiorgan NN cord-285647-9tegcrc3 381 25 injuries injury NNS cord-285647-9tegcrc3 381 26 of of IN cord-285647-9tegcrc3 381 27 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 381 28 . . . cord-285647-9tegcrc3 381 29 " " '' cord-285647-9tegcrc3 382 1 The the DT cord-285647-9tegcrc3 382 2 authors author NNS cord-285647-9tegcrc3 382 3 profiled profile VBD cord-285647-9tegcrc3 382 4 the the DT cord-285647-9tegcrc3 382 5 host host NN cord-285647-9tegcrc3 382 6 responses response NNS cord-285647-9tegcrc3 382 7 to to IN cord-285647-9tegcrc3 382 8 COVID-19 covid-19 VB cord-285647-9tegcrc3 382 9 by by IN cord-285647-9tegcrc3 382 10 means mean NNS cord-285647-9tegcrc3 382 11 of of IN cord-285647-9tegcrc3 382 12 quantitative quantitative JJ cord-285647-9tegcrc3 382 13 proteomics proteomic NNS cord-285647-9tegcrc3 382 14 in in IN cord-285647-9tegcrc3 382 15 postmortem postmortem JJ cord-285647-9tegcrc3 382 16 samples sample NNS cord-285647-9tegcrc3 382 17 of of IN cord-285647-9tegcrc3 382 18 tissues tissue NNS cord-285647-9tegcrc3 382 19 in in IN cord-285647-9tegcrc3 382 20 lungs lung NNS cord-285647-9tegcrc3 382 21 , , , cord-285647-9tegcrc3 382 22 kidney kidney NN cord-285647-9tegcrc3 382 23 , , , cord-285647-9tegcrc3 382 24 liver liver NN cord-285647-9tegcrc3 382 25 , , , cord-285647-9tegcrc3 382 26 intestine intestine NN cord-285647-9tegcrc3 382 27 , , , cord-285647-9tegcrc3 382 28 brain brain NN cord-285647-9tegcrc3 382 29 , , , cord-285647-9tegcrc3 382 30 and and CC cord-285647-9tegcrc3 382 31 heart heart NN cord-285647-9tegcrc3 382 32 . . . cord-285647-9tegcrc3 383 1 They -PRON- PRP cord-285647-9tegcrc3 383 2 reported report VBD cord-285647-9tegcrc3 383 3 differentially differentially RB cord-285647-9tegcrc3 383 4 expressed express VBN cord-285647-9tegcrc3 383 5 proteins protein NNS cord-285647-9tegcrc3 383 6 ( ( -LRB- cord-285647-9tegcrc3 383 7 DEPs dep NNS cord-285647-9tegcrc3 383 8 ) ) -RRB- cord-285647-9tegcrc3 383 9 for for IN cord-285647-9tegcrc3 383 10 these these DT cord-285647-9tegcrc3 383 11 organs organ NNS cord-285647-9tegcrc3 383 12 as as RB cord-285647-9tegcrc3 383 13 well well RB cord-285647-9tegcrc3 383 14 as as IN cord-285647-9tegcrc3 383 15 virus virus NN cord-285647-9tegcrc3 383 16 - - HYPH cord-285647-9tegcrc3 383 17 host host NN cord-285647-9tegcrc3 383 18 PPIs ppi NNS cord-285647-9tegcrc3 383 19 between between IN cord-285647-9tegcrc3 383 20 23 23 CD cord-285647-9tegcrc3 383 21 virus virus NN cord-285647-9tegcrc3 383 22 proteins protein NNS cord-285647-9tegcrc3 383 23 and and CC cord-285647-9tegcrc3 383 24 110 110 CD cord-285647-9tegcrc3 383 25 interacting interact VBG cord-285647-9tegcrc3 383 26 DEPs dep NNS cord-285647-9tegcrc3 383 27 differentially differentially RB cord-285647-9tegcrc3 383 28 regulated regulate VBN cord-285647-9tegcrc3 383 29 in in IN cord-285647-9tegcrc3 383 30 postmortem postmortem JJ cord-285647-9tegcrc3 383 31 lung lung NN cord-285647-9tegcrc3 383 32 tissues tissue NNS cord-285647-9tegcrc3 383 33 . . . cord-285647-9tegcrc3 384 1 According accord VBG cord-285647-9tegcrc3 384 2 to to IN cord-285647-9tegcrc3 384 3 their -PRON- PRP$ cord-285647-9tegcrc3 384 4 results result NNS cord-285647-9tegcrc3 384 5 , , , cord-285647-9tegcrc3 384 6 most most JJS cord-285647-9tegcrc3 384 7 DEPs dep NNS cord-285647-9tegcrc3 384 8 ( ( -LRB- cord-285647-9tegcrc3 384 9 70.5 70.5 CD cord-285647-9tegcrc3 384 10 % % NN cord-285647-9tegcrc3 384 11 ) ) -RRB- cord-285647-9tegcrc3 384 12 appears appear VBZ cord-285647-9tegcrc3 384 13 in in IN cord-285647-9tegcrc3 384 14 the the DT cord-285647-9tegcrc3 384 15 lungs lung NNS cord-285647-9tegcrc3 384 16 , , , cord-285647-9tegcrc3 384 17 followed follow VBN cord-285647-9tegcrc3 384 18 by by IN cord-285647-9tegcrc3 384 19 kidney kidney NN cord-285647-9tegcrc3 384 20 ( ( -LRB- cord-285647-9tegcrc3 384 21 16.5 16.5 CD cord-285647-9tegcrc3 384 22 % % NN cord-285647-9tegcrc3 384 23 ) ) -RRB- cord-285647-9tegcrc3 384 24 . . . cord-285647-9tegcrc3 385 1 Additionally additionally RB cord-285647-9tegcrc3 385 2 , , , cord-285647-9tegcrc3 385 3 Qiu Qiu NNP cord-285647-9tegcrc3 385 4 et et FW cord-285647-9tegcrc3 385 5 al al NNP cord-285647-9tegcrc3 385 6 . . . cord-285647-9tegcrc3 386 1 75 75 CD cord-285647-9tegcrc3 386 2 identified identify VBN cord-285647-9tegcrc3 386 3 biological biological JJ cord-285647-9tegcrc3 386 4 processes process NNS cord-285647-9tegcrc3 386 5 that that WDT cord-285647-9tegcrc3 386 6 were be VBD cord-285647-9tegcrc3 386 7 up up RB cord-285647-9tegcrc3 386 8 - - HYPH cord-285647-9tegcrc3 386 9 or or CC cord-285647-9tegcrc3 386 10 down down RB cord-285647-9tegcrc3 386 11 - - HYPH cord-285647-9tegcrc3 386 12 regulated regulate VBN cord-285647-9tegcrc3 386 13 in in IN cord-285647-9tegcrc3 386 14 the the DT cord-285647-9tegcrc3 386 15 six six CD cord-285647-9tegcrc3 386 16 postmortem postmortem JJ cord-285647-9tegcrc3 386 17 tissue tissue NN cord-285647-9tegcrc3 386 18 types type NNS cord-285647-9tegcrc3 386 19 . . . cord-285647-9tegcrc3 387 1 They -PRON- PRP cord-285647-9tegcrc3 387 2 found find VBD cord-285647-9tegcrc3 387 3 that that IN cord-285647-9tegcrc3 387 4 most most JJS cord-285647-9tegcrc3 387 5 up up RB cord-285647-9tegcrc3 387 6 - - HYPH cord-285647-9tegcrc3 387 7 regulated regulate VBN cord-285647-9tegcrc3 387 8 processes process NNS cord-285647-9tegcrc3 387 9 in in IN cord-285647-9tegcrc3 387 10 the the DT cord-285647-9tegcrc3 387 11 lungs lung NNS cord-285647-9tegcrc3 387 12 correspond correspond VBP cord-285647-9tegcrc3 387 13 to to IN cord-285647-9tegcrc3 387 14 processes process NNS cord-285647-9tegcrc3 387 15 related relate VBN cord-285647-9tegcrc3 387 16 to to IN cord-285647-9tegcrc3 387 17 the the DT cord-285647-9tegcrc3 387 18 response response NN cord-285647-9tegcrc3 387 19 to to IN cord-285647-9tegcrc3 387 20 inflammation inflammation NN cord-285647-9tegcrc3 387 21 and and CC cord-285647-9tegcrc3 387 22 to to IN cord-285647-9tegcrc3 387 23 immune immune JJ cord-285647-9tegcrc3 387 24 response response NN cord-285647-9tegcrc3 387 25 . . . cord-285647-9tegcrc3 388 1 However however RB cord-285647-9tegcrc3 388 2 , , , cord-285647-9tegcrc3 388 3 pathways pathway NNS cord-285647-9tegcrc3 388 4 related relate VBN cord-285647-9tegcrc3 388 5 to to IN cord-285647-9tegcrc3 388 6 cell cell NN cord-285647-9tegcrc3 388 7 morphology morphology NN cord-285647-9tegcrc3 388 8 , , , cord-285647-9tegcrc3 388 9 such such JJ cord-285647-9tegcrc3 388 10 as as IN cord-285647-9tegcrc3 388 11 the the DT cord-285647-9tegcrc3 388 12 establishment establishment NN cord-285647-9tegcrc3 388 13 of of IN cord-285647-9tegcrc3 388 14 endothelial endothelial JJ cord-285647-9tegcrc3 388 15 barriers barrier NNS cord-285647-9tegcrc3 388 16 , , , cord-285647-9tegcrc3 388 17 were be VBD cord-285647-9tegcrc3 388 18 down down RB cord-285647-9tegcrc3 388 19 - - HYPH cord-285647-9tegcrc3 388 20 regulated regulate VBN cord-285647-9tegcrc3 388 21 in in IN cord-285647-9tegcrc3 388 22 the the DT cord-285647-9tegcrc3 388 23 lungs lung NNS cord-285647-9tegcrc3 388 24 , , , cord-285647-9tegcrc3 388 25 which which WDT cord-285647-9tegcrc3 388 26 was be VBD cord-285647-9tegcrc3 388 27 interpreted interpret VBN cord-285647-9tegcrc3 388 28 as as IN cord-285647-9tegcrc3 388 29 a a DT cord-285647-9tegcrc3 388 30 confirmation confirmation NN cord-285647-9tegcrc3 388 31 that that IN cord-285647-9tegcrc3 388 32 the the DT cord-285647-9tegcrc3 388 33 lungs lung NNS cord-285647-9tegcrc3 388 34 are be VBP cord-285647-9tegcrc3 388 35 the the DT cord-285647-9tegcrc3 388 36 main main JJ cord-285647-9tegcrc3 388 37 focus focus NN cord-285647-9tegcrc3 388 38 of of IN cord-285647-9tegcrc3 388 39 virus virus NN cord-285647-9tegcrc3 388 40 - - HYPH cord-285647-9tegcrc3 388 41 host host NN cord-285647-9tegcrc3 388 42 fights fight NNS cord-285647-9tegcrc3 388 43 . . . cord-285647-9tegcrc3 389 1 Other other JJ cord-285647-9tegcrc3 389 2 fundamental fundamental JJ cord-285647-9tegcrc3 389 3 processes process NNS cord-285647-9tegcrc3 389 4 in in IN cord-285647-9tegcrc3 389 5 the the DT cord-285647-9tegcrc3 389 6 six six CD cord-285647-9tegcrc3 389 7 organs organ NNS cord-285647-9tegcrc3 389 8 analyzed analyze VBD cord-285647-9tegcrc3 389 9 postmortem postmortem NNS cord-285647-9tegcrc3 389 10 were be VBD cord-285647-9tegcrc3 389 11 significantly significantly RB cord-285647-9tegcrc3 389 12 down down RB cord-285647-9tegcrc3 389 13 - - HYPH cord-285647-9tegcrc3 389 14 regulated regulated JJ cord-285647-9tegcrc3 389 15 , , , cord-285647-9tegcrc3 389 16 which which WDT cord-285647-9tegcrc3 389 17 include include VBP cord-285647-9tegcrc3 389 18 processes process NNS cord-285647-9tegcrc3 389 19 related relate VBN cord-285647-9tegcrc3 389 20 to to IN cord-285647-9tegcrc3 389 21 organ organ NN cord-285647-9tegcrc3 389 22 movement movement NN cord-285647-9tegcrc3 389 23 , , , cord-285647-9tegcrc3 389 24 respiration respiration NN cord-285647-9tegcrc3 389 25 , , , cord-285647-9tegcrc3 389 26 and and CC cord-285647-9tegcrc3 389 27 metabolism metabolism NN cord-285647-9tegcrc3 389 28 . . . cord-285647-9tegcrc3 390 1 From from IN cord-285647-9tegcrc3 390 2 the the DT cord-285647-9tegcrc3 390 3 59 59 CD cord-285647-9tegcrc3 390 4 proteins protein NNS cord-285647-9tegcrc3 390 5 that that WDT cord-285647-9tegcrc3 390 6 we -PRON- PRP cord-285647-9tegcrc3 390 7 reported report VBD cord-285647-9tegcrc3 390 8 here here RB cord-285647-9tegcrc3 390 9 as as IN cord-285647-9tegcrc3 390 10 the the DT cord-285647-9tegcrc3 390 11 ones one NNS cord-285647-9tegcrc3 390 12 with with IN cord-285647-9tegcrc3 390 13 the the DT cord-285647-9tegcrc3 390 14 largest large JJS cord-285647-9tegcrc3 390 15 effect effect NN cord-285647-9tegcrc3 390 16 on on IN cord-285647-9tegcrc3 390 17 perturbing perturb VBG cord-285647-9tegcrc3 390 18 those those DT cord-285647-9tegcrc3 390 19 38 38 CD cord-285647-9tegcrc3 390 20 proteins protein NNS cord-285647-9tegcrc3 390 21 identified identify VBN cord-285647-9tegcrc3 390 22 in in IN cord-285647-9tegcrc3 390 23 human human JJ cord-285647-9tegcrc3 390 24 diseases disease NNS cord-285647-9tegcrc3 390 25 ( ( -LRB- cord-285647-9tegcrc3 390 26 see see VB cord-285647-9tegcrc3 390 27 Table Table NNP cord-285647-9tegcrc3 390 28 S3 S3 NNP cord-285647-9tegcrc3 390 29 in in IN cord-285647-9tegcrc3 390 30 the the DT cord-285647-9tegcrc3 390 31 supplementary supplementary JJ cord-285647-9tegcrc3 390 32 material material NN cord-285647-9tegcrc3 390 33 ) ) -RRB- cord-285647-9tegcrc3 390 34 , , , cord-285647-9tegcrc3 390 35 18 18 CD cord-285647-9tegcrc3 390 36 were be VBD cord-285647-9tegcrc3 390 37 found find VBN cord-285647-9tegcrc3 390 38 to to TO cord-285647-9tegcrc3 390 39 be be VB cord-285647-9tegcrc3 390 40 down down RB cord-285647-9tegcrc3 390 41 - - HYPH cord-285647-9tegcrc3 390 42 regulated regulate VBN cord-285647-9tegcrc3 390 43 in in IN cord-285647-9tegcrc3 390 44 the the DT cord-285647-9tegcrc3 390 45 lungs lung NNS cord-285647-9tegcrc3 390 46 by by IN cord-285647-9tegcrc3 390 47 Qiu Qiu NNP cord-285647-9tegcrc3 390 48 et et FW cord-285647-9tegcrc3 390 49 al al NNP cord-285647-9tegcrc3 390 50 . . . cord-285647-9tegcrc3 391 1 75 75 CD cord-285647-9tegcrc3 392 1 If if IN cord-285647-9tegcrc3 392 2 we -PRON- PRP cord-285647-9tegcrc3 392 3 make make VBP cord-285647-9tegcrc3 392 4 the the DT cord-285647-9tegcrc3 392 5 corresponding corresponding JJ cord-285647-9tegcrc3 392 6 adjustment adjustment NN cord-285647-9tegcrc3 392 7 , , , cord-285647-9tegcrc3 392 8 by by IN cord-285647-9tegcrc3 392 9 considering consider VBG cord-285647-9tegcrc3 392 10 that that DT cord-285647-9tegcrc3 393 1 Qiu Qiu NNP cord-285647-9tegcrc3 393 2 et et FW cord-285647-9tegcrc3 393 3 al al NNP cord-285647-9tegcrc3 393 4 . . . cord-285647-9tegcrc3 394 1 75 75 CD cord-285647-9tegcrc3 394 2 considered consider VBN cord-285647-9tegcrc3 394 3 110 110 CD cord-285647-9tegcrc3 394 4 instead instead RB cord-285647-9tegcrc3 394 5 of of IN cord-285647-9tegcrc3 394 6 209 209 CD cord-285647-9tegcrc3 394 7 proteins protein NNS cord-285647-9tegcrc3 394 8 in in IN cord-285647-9tegcrc3 394 9 the the DT cord-285647-9tegcrc3 394 10 PPI PPI NNP cord-285647-9tegcrc3 394 11 , , , cord-285647-9tegcrc3 394 12 the the DT cord-285647-9tegcrc3 394 13 previous previous JJ cord-285647-9tegcrc3 394 14 number number NN cord-285647-9tegcrc3 394 15 represents represent VBZ cord-285647-9tegcrc3 394 16 58.1 58.1 CD cord-285647-9tegcrc3 394 17 % % NN cord-285647-9tegcrc3 394 18 of of IN cord-285647-9tegcrc3 394 19 proteins protein NNS cord-285647-9tegcrc3 394 20 predicted predict VBN cord-285647-9tegcrc3 394 21 here here RB cord-285647-9tegcrc3 394 22 and and CC cord-285647-9tegcrc3 394 23 experimentally experimentally RB cord-285647-9tegcrc3 394 24 found find VBN cord-285647-9tegcrc3 394 25 as as IN cord-285647-9tegcrc3 394 26 down down RB cord-285647-9tegcrc3 394 27 - - HYPH cord-285647-9tegcrc3 394 28 regulated regulate VBN cord-285647-9tegcrc3 394 29 in in IN cord-285647-9tegcrc3 394 30 the the DT cord-285647-9tegcrc3 394 31 lungs lung NNS cord-285647-9tegcrc3 394 32 . . . cord-285647-9tegcrc3 395 1 From from IN cord-285647-9tegcrc3 395 2 the the DT cord-285647-9tegcrc3 395 3 rest rest NN cord-285647-9tegcrc3 395 4 of of IN cord-285647-9tegcrc3 395 5 the the DT cord-285647-9tegcrc3 395 6 proteins protein NNS cord-285647-9tegcrc3 395 7 , , , cord-285647-9tegcrc3 395 8 which which WDT cord-285647-9tegcrc3 395 9 were be VBD cord-285647-9tegcrc3 395 10 not not RB cord-285647-9tegcrc3 395 11 found find VBN cord-285647-9tegcrc3 395 12 as as IN cord-285647-9tegcrc3 395 13 having have VBG cord-285647-9tegcrc3 395 14 the the DT cord-285647-9tegcrc3 395 15 largest large JJS cord-285647-9tegcrc3 395 16 effect effect NN cord-285647-9tegcrc3 395 17 on on IN cord-285647-9tegcrc3 395 18 perturbing perturb VBG cord-285647-9tegcrc3 395 19 proteins protein NNS cord-285647-9tegcrc3 395 20 identified identify VBN cord-285647-9tegcrc3 395 21 in in IN cord-285647-9tegcrc3 395 22 human human JJ cord-285647-9tegcrc3 395 23 disease disease NN cord-285647-9tegcrc3 395 24 , , , cord-285647-9tegcrc3 395 25 only only RB cord-285647-9tegcrc3 395 26 29.1 29.1 CD cord-285647-9tegcrc3 395 27 % % NN cord-285647-9tegcrc3 395 28 were be VBD cord-285647-9tegcrc3 395 29 reported report VBN cord-285647-9tegcrc3 395 30 by by IN cord-285647-9tegcrc3 395 31 Qiu Qiu NNP cord-285647-9tegcrc3 395 32 et et FW cord-285647-9tegcrc3 395 33 al al NNP cord-285647-9tegcrc3 395 34 . . . cord-285647-9tegcrc3 396 1 75 75 CD cord-285647-9tegcrc3 396 2 to to TO cord-285647-9tegcrc3 396 3 be be VB cord-285647-9tegcrc3 396 4 down down RB cord-285647-9tegcrc3 396 5 - - HYPH cord-285647-9tegcrc3 396 6 regulated regulate VBN cord-285647-9tegcrc3 396 7 in in IN cord-285647-9tegcrc3 396 8 the the DT cord-285647-9tegcrc3 396 9 postmortem postmortem JJ cord-285647-9tegcrc3 396 10 analysis analysis NN cord-285647-9tegcrc3 396 11 of of IN cord-285647-9tegcrc3 396 12 patients patient NNS cord-285647-9tegcrc3 396 13 ' ' POS cord-285647-9tegcrc3 396 14 lungs lung NNS cord-285647-9tegcrc3 396 15 . . . cord-285647-9tegcrc3 397 1 Among among IN cord-285647-9tegcrc3 397 2 the the DT cord-285647-9tegcrc3 397 3 proteins protein NNS cord-285647-9tegcrc3 397 4 reported report VBN cord-285647-9tegcrc3 397 5 in in IN cord-285647-9tegcrc3 397 6 Table Table NNP cord-285647-9tegcrc3 397 7 S3 S3 NNP cord-285647-9tegcrc3 397 8 of of IN cord-285647-9tegcrc3 397 9 the the DT cord-285647-9tegcrc3 397 10 supplementary supplementary JJ cord-285647-9tegcrc3 397 11 _SP cord-285647-9tegcrc3 397 12 material material NN cord-285647-9tegcrc3 397 13 and and CC cord-285647-9tegcrc3 397 14 by by IN cord-285647-9tegcrc3 397 15 Qiu Qiu NNP cord-285647-9tegcrc3 397 16 et et FW cord-285647-9tegcrc3 397 17 al al NNP cord-285647-9tegcrc3 397 18 . . NNP cord-285647-9tegcrc3 397 19 , , , cord-285647-9tegcrc3 397 20 we -PRON- PRP cord-285647-9tegcrc3 397 21 have have VBP cord-285647-9tegcrc3 397 22 ARF6 ARF6 NNP cord-285647-9tegcrc3 397 23 , , , cord-285647-9tegcrc3 397 24 RTN4 RTN4 NNP cord-285647-9tegcrc3 397 25 , , , cord-285647-9tegcrc3 397 26 RAB7A rab7a NN cord-285647-9tegcrc3 397 27 , , , cord-285647-9tegcrc3 397 28 6NG5 6ng5 CD cord-285647-9tegcrc3 397 29 , , , cord-285647-9tegcrc3 397 30 _SP cord-285647-9tegcrc3 397 31 REEP5 REEP5 NNP cord-285647-9tegcrc3 397 32 , , , cord-285647-9tegcrc3 397 33 VPS11 VPS11 NNP cord-285647-9tegcrc3 397 34 , , , cord-285647-9tegcrc3 397 35 RHOA RHOA NNP cord-285647-9tegcrc3 397 36 , , , cord-285647-9tegcrc3 397 37 RAB5C rab5c NN cord-285647-9tegcrc3 397 38 , , , cord-285647-9tegcrc3 397 39 among among IN cord-285647-9tegcrc3 397 40 others other NNS cord-285647-9tegcrc3 397 41 . . . cord-285647-9tegcrc3 398 1 Finally finally RB cord-285647-9tegcrc3 398 2 , , , cord-285647-9tegcrc3 398 3 among among IN cord-285647-9tegcrc3 398 4 the the DT cord-285647-9tegcrc3 398 5 proteins protein NNS cord-285647-9tegcrc3 398 6 mainly mainly RB cord-285647-9tegcrc3 398 7 expressed express VBN cord-285647-9tegcrc3 398 8 outside outside IN cord-285647-9tegcrc3 398 9 the the DT cord-285647-9tegcrc3 398 10 lungs lung NNS cord-285647-9tegcrc3 398 11 that that WDT cord-285647-9tegcrc3 398 12 are be VBP cord-285647-9tegcrc3 398 13 predicted predict VBN cord-285647-9tegcrc3 398 14 in in IN cord-285647-9tegcrc3 398 15 this this DT cord-285647-9tegcrc3 398 16 work work NN cord-285647-9tegcrc3 398 17 to to TO cord-285647-9tegcrc3 398 18 be be VB cord-285647-9tegcrc3 398 19 significantly significantly RB cord-285647-9tegcrc3 398 20 perturbed perturb VBN cord-285647-9tegcrc3 398 21 , , , cord-285647-9tegcrc3 398 22 we -PRON- PRP cord-285647-9tegcrc3 398 23 have have VBP cord-285647-9tegcrc3 398 24 five five CD cord-285647-9tegcrc3 398 25 that that WDT cord-285647-9tegcrc3 398 26 were be VBD cord-285647-9tegcrc3 398 27 found find VBN cord-285647-9tegcrc3 398 28 by by IN cord-285647-9tegcrc3 398 29 Qiu Qiu NNP cord-285647-9tegcrc3 398 30 et et FW cord-285647-9tegcrc3 398 31 al al NNP cord-285647-9tegcrc3 398 32 . . . cord-285647-9tegcrc3 399 1 75 75 CD cord-285647-9tegcrc3 399 2 to to TO cord-285647-9tegcrc3 399 3 be be VB cord-285647-9tegcrc3 399 4 up up RB cord-285647-9tegcrc3 399 5 - - HYPH cord-285647-9tegcrc3 399 6 regulated regulate VBN cord-285647-9tegcrc3 399 7 in in IN cord-285647-9tegcrc3 399 8 the the DT cord-285647-9tegcrc3 399 9 different different JJ cord-285647-9tegcrc3 399 10 organs organ NNS cord-285647-9tegcrc3 399 11 analyzed analyze VBN cord-285647-9tegcrc3 399 12 by by IN cord-285647-9tegcrc3 399 13 them -PRON- PRP cord-285647-9tegcrc3 399 14 . . . cord-285647-9tegcrc3 400 1 From from IN cord-285647-9tegcrc3 400 2 the the DT cord-285647-9tegcrc3 400 3 proteins protein NNS cord-285647-9tegcrc3 400 4 included include VBN cord-285647-9tegcrc3 400 5 in in IN cord-285647-9tegcrc3 400 6 Table Table NNP cord-285647-9tegcrc3 400 7 I -PRON- PRP cord-285647-9tegcrc3 400 8 , , , cord-285647-9tegcrc3 400 9 Qiu Qiu NNP cord-285647-9tegcrc3 400 10 et et FW cord-285647-9tegcrc3 400 11 al al NNP cord-285647-9tegcrc3 400 12 . . . cord-285647-9tegcrc3 401 1 75 75 CD cord-285647-9tegcrc3 401 2 reported report VBD cord-285647-9tegcrc3 401 3 the the DT cord-285647-9tegcrc3 401 4 following follow VBG cord-285647-9tegcrc3 401 5 ones one NNS cord-285647-9tegcrc3 401 6 up up RB cord-285647-9tegcrc3 401 7 - - HYPH cord-285647-9tegcrc3 401 8 regulated regulate VBN cord-285647-9tegcrc3 401 9 : : : cord-285647-9tegcrc3 402 1 PKP2 PKP2 NNP cord-285647-9tegcrc3 402 2 ( ( -LRB- cord-285647-9tegcrc3 402 3 heart heart NN cord-285647-9tegcrc3 402 4 ) ) -RRB- cord-285647-9tegcrc3 402 5 , , , cord-285647-9tegcrc3 402 6 REEP6 REEP6 NNS cord-285647-9tegcrc3 402 7 ( ( -LRB- cord-285647-9tegcrc3 402 8 liver liver NN cord-285647-9tegcrc3 402 9 ) ) -RRB- cord-285647-9tegcrc3 402 10 , , , cord-285647-9tegcrc3 402 11 HOOK1 hook1 NN cord-285647-9tegcrc3 403 1 ( ( -LRB- cord-285647-9tegcrc3 403 2 several several JJ cord-285647-9tegcrc3 403 3 organs organ NNS cord-285647-9tegcrc3 403 4 ) ) -RRB- cord-285647-9tegcrc3 403 5 , , . cord-285647-9tegcrc3 404 1 ATP5ME ATP5ME NNP cord-285647-9tegcrc3 404 2 ( ( -LRB- cord-285647-9tegcrc3 404 3 heart heart NN cord-285647-9tegcrc3 404 4 ) ) -RRB- cord-285647-9tegcrc3 404 5 , , , cord-285647-9tegcrc3 404 6 and and CC cord-285647-9tegcrc3 404 7 SLC27A2 SLC27A2 NNS cord-285647-9tegcrc3 404 8 ( ( -LRB- cord-285647-9tegcrc3 404 9 liver liver NN cord-285647-9tegcrc3 404 10 and and CC cord-285647-9tegcrc3 404 11 kidney kidney NN cord-285647-9tegcrc3 404 12 ) ) -RRB- cord-285647-9tegcrc3 404 13 . . . cord-285647-9tegcrc3 405 1 They -PRON- PRP cord-285647-9tegcrc3 405 2 also also RB cord-285647-9tegcrc3 405 3 reported report VBD cord-285647-9tegcrc3 405 4 CEP43 CEP43 NNP cord-285647-9tegcrc3 405 5 ( ( -LRB- cord-285647-9tegcrc3 405 6 reported report VBN cord-285647-9tegcrc3 405 7 as as IN cord-285647-9tegcrc3 405 8 FGFR1OP fgfr1op NN cord-285647-9tegcrc3 405 9 ) ) -RRB- cord-285647-9tegcrc3 405 10 as as IN cord-285647-9tegcrc3 405 11 downregulated downregulate VBN cord-285647-9tegcrc3 405 12 in in IN cord-285647-9tegcrc3 405 13 the the DT cord-285647-9tegcrc3 405 14 brain brain NN cord-285647-9tegcrc3 405 15 . . . cord-285647-9tegcrc3 406 1 We -PRON- PRP cord-285647-9tegcrc3 406 2 should should MD cord-285647-9tegcrc3 406 3 remark remark VB cord-285647-9tegcrc3 406 4 that that IN cord-285647-9tegcrc3 406 5 we -PRON- PRP cord-285647-9tegcrc3 406 6 have have VBP cord-285647-9tegcrc3 406 7 considered consider VBN cord-285647-9tegcrc3 406 8 here here RB cord-285647-9tegcrc3 406 9 many many JJ cord-285647-9tegcrc3 406 10 more more JJR cord-285647-9tegcrc3 406 11 organs organ NNS cord-285647-9tegcrc3 406 12 than than IN cord-285647-9tegcrc3 406 13 the the DT cord-285647-9tegcrc3 406 14 six six CD cord-285647-9tegcrc3 406 15 ones one NNS cord-285647-9tegcrc3 406 16 studied study VBN cord-285647-9tegcrc3 406 17 by by IN cord-285647-9tegcrc3 406 18 Qiu Qiu NNP cord-285647-9tegcrc3 406 19 et et FW cord-285647-9tegcrc3 406 20 al al NNP cord-285647-9tegcrc3 406 21 . . . cord-285647-9tegcrc3 407 1 75 75 CD cord-285647-9tegcrc3 407 2 _SP cord-285647-9tegcrc3 408 1 There there EX cord-285647-9tegcrc3 408 2 are be VBP cord-285647-9tegcrc3 408 3 no no DT cord-285647-9tegcrc3 408 4 doubts doubt NNS cord-285647-9tegcrc3 408 5 that that IN cord-285647-9tegcrc3 408 6 in in IN cord-285647-9tegcrc3 408 7 considering consider VBG cord-285647-9tegcrc3 408 8 a a DT cord-285647-9tegcrc3 408 9 diffusive diffusive JJ cord-285647-9tegcrc3 408 10 propagation propagation NN cord-285647-9tegcrc3 408 11 of of IN cord-285647-9tegcrc3 408 12 perturbations perturbation NNS cord-285647-9tegcrc3 408 13 among among IN cord-285647-9tegcrc3 408 14 proteins protein NNS cord-285647-9tegcrc3 408 15 in in IN cord-285647-9tegcrc3 408 16 a a DT cord-285647-9tegcrc3 408 17 PPI PPI NNP cord-285647-9tegcrc3 408 18 , , , cord-285647-9tegcrc3 408 19 we -PRON- PRP cord-285647-9tegcrc3 408 20 have have VBP cord-285647-9tegcrc3 408 21 made make VBN cord-285647-9tegcrc3 408 22 a a DT cord-285647-9tegcrc3 408 23 FIG fig NN cord-285647-9tegcrc3 408 24 . . . cord-285647-9tegcrc3 409 1 6 6 LS cord-285647-9tegcrc3 409 2 . . . cord-285647-9tegcrc3 410 1 PI PI NNP cord-285647-9tegcrc3 410 2 metaplex metaplex NN cord-285647-9tegcrc3 410 3 . . . cord-285647-9tegcrc3 411 1 In in IN cord-285647-9tegcrc3 411 2 the the DT cord-285647-9tegcrc3 411 3 metaplex metaplex NN cord-285647-9tegcrc3 411 4 , , , cord-285647-9tegcrc3 411 5 every every DT cord-285647-9tegcrc3 411 6 node node NN cord-285647-9tegcrc3 411 7 of of IN cord-285647-9tegcrc3 411 8 the the DT cord-285647-9tegcrc3 411 9 PPI PPI NNP cord-285647-9tegcrc3 411 10 corresponds correspond VBZ cord-285647-9tegcrc3 411 11 to to IN cord-285647-9tegcrc3 411 12 a a DT cord-285647-9tegcrc3 411 13 protein protein NN cord-285647-9tegcrc3 411 14 and and CC cord-285647-9tegcrc3 411 15 its -PRON- PRP$ cord-285647-9tegcrc3 411 16 crowded crowded JJ cord-285647-9tegcrc3 411 17 intracellular intracellular JJ cord-285647-9tegcrc3 411 18 space space NN cord-285647-9tegcrc3 411 19 . . . cord-285647-9tegcrc3 412 1 There there EX cord-285647-9tegcrc3 412 2 is be VBZ cord-285647-9tegcrc3 412 3 an an DT cord-285647-9tegcrc3 412 4 internal internal JJ cord-285647-9tegcrc3 412 5 dynamics dynamic NNS cord-285647-9tegcrc3 412 6 in in IN cord-285647-9tegcrc3 412 7 the the DT cord-285647-9tegcrc3 412 8 nodes node NNS cord-285647-9tegcrc3 412 9 and and CC cord-285647-9tegcrc3 412 10 an an DT cord-285647-9tegcrc3 412 11 external external JJ cord-285647-9tegcrc3 412 12 between between IN cord-285647-9tegcrc3 412 13 the the DT cord-285647-9tegcrc3 412 14 nodes node NNS cord-285647-9tegcrc3 412 15 . . . cord-285647-9tegcrc3 413 1 few few JJ cord-285647-9tegcrc3 413 2 simplifications simplification NNS cord-285647-9tegcrc3 413 3 and and CC cord-285647-9tegcrc3 413 4 assumptions assumption NNS cord-285647-9tegcrc3 413 5 . . . cord-285647-9tegcrc3 414 1 Every every DT cord-285647-9tegcrc3 414 2 protein protein NN cord-285647-9tegcrc3 414 3 is be VBZ cord-285647-9tegcrc3 414 4 embedded embed VBN cord-285647-9tegcrc3 414 5 in in IN cord-285647-9tegcrc3 414 6 an an DT cord-285647-9tegcrc3 414 7 intracellular intracellular JJ cord-285647-9tegcrc3 414 8 crowded crowded JJ cord-285647-9tegcrc3 414 9 environment environment NN cord-285647-9tegcrc3 414 10 , , , cord-285647-9tegcrc3 414 11 which which WDT cord-285647-9tegcrc3 414 12 drives drive VBZ cord-285647-9tegcrc3 414 13 its -PRON- PRP$ cord-285647-9tegcrc3 414 14 diffusive diffusive JJ cord-285647-9tegcrc3 414 15 mechanism mechanism NN cord-285647-9tegcrc3 414 16 . . . cord-285647-9tegcrc3 415 1 Nowadays nowadays RB cord-285647-9tegcrc3 415 2 , , , cord-285647-9tegcrc3 415 3 it -PRON- PRP cord-285647-9tegcrc3 415 4 is be VBZ cord-285647-9tegcrc3 415 5 well well RB cord-285647-9tegcrc3 415 6 - - HYPH cord-285647-9tegcrc3 415 7 established establish VBN cord-285647-9tegcrc3 415 8 that that IN cord-285647-9tegcrc3 415 9 this this DT cord-285647-9tegcrc3 415 10 environment environment NN cord-285647-9tegcrc3 415 11 is be VBZ cord-285647-9tegcrc3 415 12 conducive conducive JJ cord-285647-9tegcrc3 415 13 to to IN cord-285647-9tegcrc3 415 14 molecular molecular JJ cord-285647-9tegcrc3 415 15 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 415 16 processes process NNS cord-285647-9tegcrc3 415 17 . . . cord-285647-9tegcrc3 416 1 As as IN cord-285647-9tegcrc3 416 2 remarked remark VBN cord-285647-9tegcrc3 416 3 by by IN cord-285647-9tegcrc3 416 4 Guigas Guigas NNP cord-285647-9tegcrc3 416 5 and and CC cord-285647-9tegcrc3 416 6 Weiss Weiss NNP cord-285647-9tegcrc3 416 7 , , , cord-285647-9tegcrc3 416 8 27 27 CD cord-285647-9tegcrc3 416 9 far far RB cord-285647-9tegcrc3 416 10 from from IN cord-285647-9tegcrc3 416 11 obstructing obstruct VBG cord-285647-9tegcrc3 416 12 cellular cellular JJ cord-285647-9tegcrc3 416 13 processes process NNS cord-285647-9tegcrc3 416 14 , , , cord-285647-9tegcrc3 416 15 subdiffusion subdiffusion NN cord-285647-9tegcrc3 416 16 increases increase VBZ cord-285647-9tegcrc3 416 17 the the DT cord-285647-9tegcrc3 416 18 probability probability NN cord-285647-9tegcrc3 416 19 of of IN cord-285647-9tegcrc3 416 20 finding find VBG cord-285647-9tegcrc3 416 21 a a DT cord-285647-9tegcrc3 416 22 nearby nearby JJ cord-285647-9tegcrc3 416 23 target target NN cord-285647-9tegcrc3 416 24 by by IN cord-285647-9tegcrc3 416 25 a a DT cord-285647-9tegcrc3 416 26 given give VBN cord-285647-9tegcrc3 416 27 protein protein NN cord-285647-9tegcrc3 416 28 , , , cord-285647-9tegcrc3 416 29 and and CC cord-285647-9tegcrc3 416 30 therefore therefore RB cord-285647-9tegcrc3 416 31 , , , cord-285647-9tegcrc3 416 32 it -PRON- PRP cord-285647-9tegcrc3 416 33 facilitates facilitate VBZ cord-285647-9tegcrc3 416 34 protein protein NN cord-285647-9tegcrc3 416 35 - - HYPH cord-285647-9tegcrc3 416 36 protein protein NN cord-285647-9tegcrc3 416 37 interactions interaction NNS cord-285647-9tegcrc3 416 38 . . . cord-285647-9tegcrc3 417 1 The the DT cord-285647-9tegcrc3 417 2 current current JJ cord-285647-9tegcrc3 417 3 approach approach NN cord-285647-9tegcrc3 417 4 can can MD cord-285647-9tegcrc3 417 5 be be VB cord-285647-9tegcrc3 417 6 improved improve VBN cord-285647-9tegcrc3 417 7 using use VBG cord-285647-9tegcrc3 417 8 two two CD cord-285647-9tegcrc3 417 9 recently recently RB cord-285647-9tegcrc3 417 10 developed develop VBN cord-285647-9tegcrc3 417 11 theoretical theoretical JJ cord-285647-9tegcrc3 417 12 frameworks framework NNS cord-285647-9tegcrc3 417 13 : : : cord-285647-9tegcrc3 417 14 ( ( -LRB- cord-285647-9tegcrc3 417 15 i i NN cord-285647-9tegcrc3 417 16 ) ) -RRB- cord-285647-9tegcrc3 417 17 metaplexes metaplexes NNP cord-285647-9tegcrc3 417 18 and and CC cord-285647-9tegcrc3 417 19 ( ( -LRB- cord-285647-9tegcrc3 417 20 ii ii NN cord-285647-9tegcrc3 417 21 ) ) -RRB- cord-285647-9tegcrc3 417 22 d d NN cord-285647-9tegcrc3 417 23 - - HYPH cord-285647-9tegcrc3 417 24 path path NN cord-285647-9tegcrc3 417 25 Laplacian laplacian JJ cord-285647-9tegcrc3 417 26 operators operator NNS cord-285647-9tegcrc3 417 27 on on IN cord-285647-9tegcrc3 417 28 graphs graph NNS cord-285647-9tegcrc3 417 29 . . . cord-285647-9tegcrc3 418 1 A a DT cord-285647-9tegcrc3 418 2 PPI PPI NNP cord-285647-9tegcrc3 418 3 metaplex metaplex NN cord-285647-9tegcrc3 418 4 , , , cord-285647-9tegcrc3 418 5 70 70 CD cord-285647-9tegcrc3 418 6 a a DT cord-285647-9tegcrc3 418 7 4-tuple 4-tuple CD cord-285647-9tegcrc3 418 8 ϒ ϒ NN cord-285647-9tegcrc3 418 9 = = NFP cord-285647-9tegcrc3 419 1 ( ( -LRB- cord-285647-9tegcrc3 419 2 V v NN cord-285647-9tegcrc3 419 3 , , , cord-285647-9tegcrc3 419 4 E E NNP cord-285647-9tegcrc3 419 5 , , , cord-285647-9tegcrc3 419 6 I -PRON- PRP cord-285647-9tegcrc3 419 7 , , , cord-285647-9tegcrc3 419 8 ω ω NNP cord-285647-9tegcrc3 419 9 ) ) -RRB- cord-285647-9tegcrc3 419 10 , , , cord-285647-9tegcrc3 419 11 where where WRB cord-285647-9tegcrc3 419 12 ( ( -LRB- cord-285647-9tegcrc3 419 13 V v NN cord-285647-9tegcrc3 419 14 , , , cord-285647-9tegcrc3 419 15 E E NNP cord-285647-9tegcrc3 419 16 ) ) -RRB- cord-285647-9tegcrc3 419 17 is be VBZ cord-285647-9tegcrc3 419 18 a a DT cord-285647-9tegcrc3 419 19 graph graph NN cord-285647-9tegcrc3 419 20 , , , cord-285647-9tegcrc3 419 21 ω ω ADD cord-285647-9tegcrc3 420 1 = = LS cord-285647-9tegcrc3 420 2 { { -LRB- cord-285647-9tegcrc3 420 3 j j NNP cord-285647-9tegcrc3 420 4 } } -RRB- cord-285647-9tegcrc3 420 5 k k NNP cord-285647-9tegcrc3 420 6 j=1 j=1 NNP cord-285647-9tegcrc3 420 7 is be VBZ cord-285647-9tegcrc3 420 8 a a DT cord-285647-9tegcrc3 420 9 set set NN cord-285647-9tegcrc3 420 10 of of IN cord-285647-9tegcrc3 420 11 locally locally RB cord-285647-9tegcrc3 420 12 compact compact JJ cord-285647-9tegcrc3 420 13 metric metric JJ cord-285647-9tegcrc3 420 14 spaces space NNS cord-285647-9tegcrc3 420 15 j j NNP cord-285647-9tegcrc3 420 16 with with IN cord-285647-9tegcrc3 420 17 Borel Borel NNP cord-285647-9tegcrc3 420 18 measures measure VBZ cord-285647-9tegcrc3 420 19 µ µ NNP cord-285647-9tegcrc3 420 20 j j NNP cord-285647-9tegcrc3 420 21 , , , cord-285647-9tegcrc3 420 22 and and CC cord-285647-9tegcrc3 420 23 I -PRON- PRP cord-285647-9tegcrc3 420 24 : : : cord-285647-9tegcrc3 420 25 V v NN cord-285647-9tegcrc3 420 26 → → NN cord-285647-9tegcrc3 420 27 ω ω NN cord-285647-9tegcrc3 420 28 is be VBZ cord-285647-9tegcrc3 420 29 illustrated illustrate VBN cord-285647-9tegcrc3 420 30 in in IN cord-285647-9tegcrc3 420 31 Fig Fig NNP cord-285647-9tegcrc3 420 32 . . NNP cord-285647-9tegcrc3 420 33 6 6 CD cord-285647-9tegcrc3 420 34 . . . cord-285647-9tegcrc3 421 1 Then then RB cord-285647-9tegcrc3 421 2 , , , cord-285647-9tegcrc3 421 3 we -PRON- PRP cord-285647-9tegcrc3 421 4 define define VBP cord-285647-9tegcrc3 421 5 a a DT cord-285647-9tegcrc3 421 6 dynamical dynamical JJ cord-285647-9tegcrc3 421 7 ϒ ϒ NN cord-285647-9tegcrc3 421 8 = = NFP cord-285647-9tegcrc3 422 1 ( ( -LRB- cord-285647-9tegcrc3 422 2 V v NN cord-285647-9tegcrc3 422 3 , , , cord-285647-9tegcrc3 422 4 E E NNP cord-285647-9tegcrc3 422 5 , , , cord-285647-9tegcrc3 422 6 I -PRON- PRP cord-285647-9tegcrc3 422 7 , , , cord-285647-9tegcrc3 422 8 ω ω NN cord-285647-9tegcrc3 422 9 = = NFP cord-285647-9tegcrc3 422 10 { { -LRB- cord-285647-9tegcrc3 422 11 k k NN cord-285647-9tegcrc3 422 12 } } -RRB- cord-285647-9tegcrc3 422 13 ) ) -RRB- cord-285647-9tegcrc3 422 14 on on IN cord-285647-9tegcrc3 422 15 the the DT cord-285647-9tegcrc3 422 16 metaplex metaplex NN cord-285647-9tegcrc3 422 17 as as IN cord-285647-9tegcrc3 422 18 a a DT cord-285647-9tegcrc3 422 19 tuple tuple NN cord-285647-9tegcrc3 422 20 ( ( -LRB- cord-285647-9tegcrc3 422 21 H H NNP cord-285647-9tegcrc3 422 22 , , , cord-285647-9tegcrc3 422 23 T T NNP cord-285647-9tegcrc3 422 24 ) ) -RRB- cord-285647-9tegcrc3 422 25 . . . cord-285647-9tegcrc3 423 1 Here here RB cord-285647-9tegcrc3 423 2 , , , cord-285647-9tegcrc3 423 3 H h NN cord-285647-9tegcrc3 423 4 = = SYM cord-285647-9tegcrc3 423 5 H h NN cord-285647-9tegcrc3 423 6 v v NN cord-285647-9tegcrc3 423 7 : : : cord-285647-9tegcrc3 423 8 L l NN cord-285647-9tegcrc3 423 9 2 2 CD cord-285647-9tegcrc3 423 10 ( ( -LRB- cord-285647-9tegcrc3 423 11 I -PRON- PRP cord-285647-9tegcrc3 423 12 ( ( -LRB- cord-285647-9tegcrc3 423 13 v v NN cord-285647-9tegcrc3 423 14 ) ) -RRB- cord-285647-9tegcrc3 423 15 , , , cord-285647-9tegcrc3 423 16 µ µ LS cord-285647-9tegcrc3 423 17 I -PRON- PRP cord-285647-9tegcrc3 423 18 ( ( -LRB- cord-285647-9tegcrc3 423 19 v v NN cord-285647-9tegcrc3 423 20 ) ) -RRB- cord-285647-9tegcrc3 423 21 ) ) -RRB- cord-285647-9tegcrc3 424 1 → → WDT cord-285647-9tegcrc3 424 2 L l NN cord-285647-9tegcrc3 424 3 2 2 CD cord-285647-9tegcrc3 425 1 ( ( -LRB- cord-285647-9tegcrc3 425 2 I -PRON- PRP cord-285647-9tegcrc3 425 3 ( ( -LRB- cord-285647-9tegcrc3 425 4 v v NN cord-285647-9tegcrc3 425 5 ) ) -RRB- cord-285647-9tegcrc3 425 6 , , , cord-285647-9tegcrc3 425 7 µ µ LS cord-285647-9tegcrc3 425 8 I -PRON- PRP cord-285647-9tegcrc3 425 9 ( ( -LRB- cord-285647-9tegcrc3 425 10 v v NN cord-285647-9tegcrc3 425 11 ) ) -RRB- cord-285647-9tegcrc3 425 12 ) ) -RRB- cord-285647-9tegcrc3 426 1 } } -RRB- cord-285647-9tegcrc3 427 1 v∈V v∈V NNP cord-285647-9tegcrc3 427 2 is be VBZ cord-285647-9tegcrc3 427 3 a a DT cord-285647-9tegcrc3 427 4 family family NN cord-285647-9tegcrc3 427 5 of of IN cord-285647-9tegcrc3 427 6 operators operator NNS cord-285647-9tegcrc3 427 7 such such JJ cord-285647-9tegcrc3 427 8 that that IN cord-285647-9tegcrc3 427 9 the the DT cord-285647-9tegcrc3 427 10 initial initial JJ cord-285647-9tegcrc3 427 11 value value NN cord-285647-9tegcrc3 427 12 problem problem NN cord-285647-9tegcrc3 428 1 ∂ ∂ NNP cord-285647-9tegcrc3 429 1 t t NNP cord-285647-9tegcrc3 429 2 u u NN cord-285647-9tegcrc3 429 3 v v NN cord-285647-9tegcrc3 429 4 = = SYM cord-285647-9tegcrc3 429 5 H h NN cord-285647-9tegcrc3 429 6 v v NN cord-285647-9tegcrc3 429 7 ( ( -LRB- cord-285647-9tegcrc3 429 8 u u NNP cord-285647-9tegcrc3 429 9 v v NNP cord-285647-9tegcrc3 429 10 ) ) -RRB- cord-285647-9tegcrc3 429 11 , , . cord-285647-9tegcrc3 430 1 u u NNP cord-285647-9tegcrc3 430 2 v v NNP cord-285647-9tegcrc3 430 3 | | NNP cord-285647-9tegcrc3 430 4 t=0 t=0 NNP cord-285647-9tegcrc3 430 5 = = NFP cord-285647-9tegcrc3 431 1 u u LS cord-285647-9tegcrc3 431 2 0 0 CD cord-285647-9tegcrc3 431 3 , , , cord-285647-9tegcrc3 431 4 is be VBZ cord-285647-9tegcrc3 431 5 well well RB cord-285647-9tegcrc3 431 6 - - HYPH cord-285647-9tegcrc3 431 7 posed pose VBN cord-285647-9tegcrc3 431 8 , , , cord-285647-9tegcrc3 431 9 and and CC cord-285647-9tegcrc3 431 10 T t NN cord-285647-9tegcrc3 431 11 = = SYM cord-285647-9tegcrc3 431 12 { { -LRB- cord-285647-9tegcrc3 431 13 T T NNP cord-285647-9tegcrc3 431 14 vw vw NNP cord-285647-9tegcrc3 431 15 } } -RRB- cord-285647-9tegcrc3 432 1 ( ( -LRB- cord-285647-9tegcrc3 432 2 v v IN cord-285647-9tegcrc3 432 3 , , , cord-285647-9tegcrc3 432 4 w)∈E w)∈E NNP cord-285647-9tegcrc3 432 5 is be VBZ cord-285647-9tegcrc3 432 6 a a DT cord-285647-9tegcrc3 432 7 family family NN cord-285647-9tegcrc3 432 8 of of IN cord-285647-9tegcrc3 432 9 bounded bounded JJ cord-285647-9tegcrc3 432 10 operators operator NNS cord-285647-9tegcrc3 432 11 T T NNP cord-285647-9tegcrc3 432 12 vw vw NNP cord-285647-9tegcrc3 432 13 : : : cord-285647-9tegcrc3 432 14 L l NN cord-285647-9tegcrc3 432 15 2 2 CD cord-285647-9tegcrc3 432 16 ( ( -LRB- cord-285647-9tegcrc3 432 17 I(v I(v NNP cord-285647-9tegcrc3 432 18 ) ) -RRB- cord-285647-9tegcrc3 432 19 , , , cord-285647-9tegcrc3 432 20 µ µ NN cord-285647-9tegcrc3 432 21 I(v i(v NN cord-285647-9tegcrc3 432 22 ) ) -RRB- cord-285647-9tegcrc3 432 23 ) ) -RRB- cord-285647-9tegcrc3 433 1 → → WDT cord-285647-9tegcrc3 433 2 L l NN cord-285647-9tegcrc3 433 3 2 2 CD cord-285647-9tegcrc3 433 4 ( ( -LRB- cord-285647-9tegcrc3 433 5 I(w i(w NN cord-285647-9tegcrc3 433 6 ) ) -RRB- cord-285647-9tegcrc3 433 7 , , , cord-285647-9tegcrc3 433 8 µ µ NNP cord-285647-9tegcrc3 433 9 I(w i(w NN cord-285647-9tegcrc3 433 10 ) ) -RRB- cord-285647-9tegcrc3 433 11 ) ) -RRB- cord-285647-9tegcrc3 433 12 . . . cord-285647-9tegcrc3 434 1 This this DT cord-285647-9tegcrc3 434 2 means mean VBZ cord-285647-9tegcrc3 434 3 that that IN cord-285647-9tegcrc3 434 4 inside inside IN cord-285647-9tegcrc3 434 5 a a DT cord-285647-9tegcrc3 434 6 node node NN cord-285647-9tegcrc3 434 7 of of IN cord-285647-9tegcrc3 434 8 the the DT cord-285647-9tegcrc3 434 9 metaplex metaplex NN cord-285647-9tegcrc3 434 10 , , , cord-285647-9tegcrc3 434 11 we -PRON- PRP cord-285647-9tegcrc3 434 12 consider consider VBP cord-285647-9tegcrc3 434 13 one one CD cord-285647-9tegcrc3 434 14 protein protein NN cord-285647-9tegcrc3 434 15 and and CC cord-285647-9tegcrc3 434 16 its -PRON- PRP$ cord-285647-9tegcrc3 434 17 crowded crowded JJ cord-285647-9tegcrc3 434 18 intracellular intracellular JJ cord-285647-9tegcrc3 434 19 space space NN cord-285647-9tegcrc3 434 20 . . . cord-285647-9tegcrc3 435 1 Inside inside IN cord-285647-9tegcrc3 435 2 the the DT cord-285647-9tegcrc3 435 3 nodes node NNS cord-285647-9tegcrc3 435 4 , , , cord-285647-9tegcrc3 435 5 we -PRON- PRP cord-285647-9tegcrc3 435 6 can can MD cord-285647-9tegcrc3 435 7 have have VB cord-285647-9tegcrc3 435 8 a a DT cord-285647-9tegcrc3 435 9 dynamics dynamic NNS cord-285647-9tegcrc3 435 10 like like IN cord-285647-9tegcrc3 435 11 a a DT cord-285647-9tegcrc3 435 12 time time NN cord-285647-9tegcrc3 435 13 - - HYPH cord-285647-9tegcrc3 435 14 fractional fractional JJ cord-285647-9tegcrc3 435 15 diffusion diffusion NN cord-285647-9tegcrc3 435 16 equation equation NN cord-285647-9tegcrc3 435 17 , , , cord-285647-9tegcrc3 435 18 the the DT cord-285647-9tegcrc3 435 19 fractional fractional JJ cord-285647-9tegcrc3 435 20 Fokker Fokker NNP cord-285647-9tegcrc3 435 21 - - HYPH cord-285647-9tegcrc3 435 22 Planck Planck NNP cord-285647-9tegcrc3 435 23 equation equation NN cord-285647-9tegcrc3 435 24 , , , cord-285647-9tegcrc3 435 25 or or CC cord-285647-9tegcrc3 435 26 any any DT cord-285647-9tegcrc3 435 27 other other JJ cord-285647-9tegcrc3 435 28 in in IN cord-285647-9tegcrc3 435 29 a a DT cord-285647-9tegcrc3 435 30 continuous continuous JJ cord-285647-9tegcrc3 435 31 space space NN cord-285647-9tegcrc3 435 32 . . . cord-285647-9tegcrc3 436 1 The the DT cord-285647-9tegcrc3 436 2 inter inter JJ cord-285647-9tegcrc3 436 3 - - NNS cord-285647-9tegcrc3 436 4 nodes node NNS cord-285647-9tegcrc3 436 5 dynamics dynamic NNS cord-285647-9tegcrc3 436 6 is be VBZ cord-285647-9tegcrc3 436 7 then then RB cord-285647-9tegcrc3 436 8 dominated dominate VBN cord-285647-9tegcrc3 436 9 by by IN cord-285647-9tegcrc3 436 10 a a DT cord-285647-9tegcrc3 436 11 graph graph NN cord-285647-9tegcrc3 436 12 - - HYPH cord-285647-9tegcrc3 436 13 theoretic theoretic JJ cord-285647-9tegcrc3 436 14 diffusive diffusive JJ cord-285647-9tegcrc3 436 15 model model NN cord-285647-9tegcrc3 436 16 like like IN cord-285647-9tegcrc3 436 17 the the DT cord-285647-9tegcrc3 436 18 one one NN cord-285647-9tegcrc3 436 19 presented present VBN cord-285647-9tegcrc3 436 20 here here RB cord-285647-9tegcrc3 436 21 . . . cord-285647-9tegcrc3 437 1 The the DT cord-285647-9tegcrc3 437 2 second second JJ cord-285647-9tegcrc3 437 3 possible possible JJ cord-285647-9tegcrc3 437 4 improvement improvement NN cord-285647-9tegcrc3 437 5 to to IN cord-285647-9tegcrc3 437 6 the the DT cord-285647-9tegcrc3 437 7 current current JJ cord-285647-9tegcrc3 437 8 model model NN cord-285647-9tegcrc3 437 9 can can MD cord-285647-9tegcrc3 437 10 be be VB cord-285647-9tegcrc3 437 11 made make VBN cord-285647-9tegcrc3 437 12 by by IN cord-285647-9tegcrc3 437 13 introducing introduce VBG cord-285647-9tegcrc3 437 14 the the DT cord-285647-9tegcrc3 437 15 possibility possibility NN cord-285647-9tegcrc3 437 16 of of IN cord-285647-9tegcrc3 437 17 long long JJ cord-285647-9tegcrc3 437 18 - - HYPH cord-285647-9tegcrc3 437 19 range range NN cord-285647-9tegcrc3 437 20 interactions interaction NNS cord-285647-9tegcrc3 437 21 in in IN cord-285647-9tegcrc3 437 22 the the DT cord-285647-9tegcrc3 437 23 inter inter JJ cord-285647-9tegcrc3 437 24 - - NNS cord-285647-9tegcrc3 437 25 nodes node NNS cord-285647-9tegcrc3 437 26 dynamics dynamic NNS cord-285647-9tegcrc3 437 27 in in IN cord-285647-9tegcrc3 437 28 the the DT cord-285647-9tegcrc3 437 29 PPI PPI NNP cord-285647-9tegcrc3 437 30 metaplex metaplex NN cord-285647-9tegcrc3 437 31 . . . cord-285647-9tegcrc3 438 1 That that RB cord-285647-9tegcrc3 438 2 is is RB cord-285647-9tegcrc3 438 3 , , , cord-285647-9tegcrc3 438 4 instead instead RB cord-285647-9tegcrc3 438 5 of of IN cord-285647-9tegcrc3 438 6 considering consider VBG cord-285647-9tegcrc3 438 7 the the DT cord-285647-9tegcrc3 438 8 time time NN cord-285647-9tegcrc3 438 9 - - HYPH cord-285647-9tegcrc3 438 10 fractional fractional JJ cord-285647-9tegcrc3 438 11 diffusion diffusion NN cord-285647-9tegcrc3 438 12 equation equation NN cord-285647-9tegcrc3 438 13 , , , cord-285647-9tegcrc3 438 14 which which WDT cord-285647-9tegcrc3 438 15 only only RB cord-285647-9tegcrc3 438 16 accounts account VBZ cord-285647-9tegcrc3 438 17 for for IN cord-285647-9tegcrc3 438 18 subdiffusive subdiffusive JJ cord-285647-9tegcrc3 438 19 processes process NNS cord-285647-9tegcrc3 438 20 in in IN cord-285647-9tegcrc3 438 21 the the DT cord-285647-9tegcrc3 438 22 graph graph NN cord-285647-9tegcrc3 438 23 , , , cord-285647-9tegcrc3 438 24 we -PRON- PRP cord-285647-9tegcrc3 438 25 can can MD cord-285647-9tegcrc3 438 26 use use VB cord-285647-9tegcrc3 438 27 the the DT cord-285647-9tegcrc3 438 28 following following JJ cord-285647-9tegcrc3 438 29 generalization generalization NN cord-285647-9tegcrc3 438 30 , , , cord-285647-9tegcrc3 438 31 which which WDT cord-285647-9tegcrc3 438 32 incorporates incorporate VBZ cord-285647-9tegcrc3 438 33 the the DT cord-285647-9tegcrc3 438 34 d d NN cord-285647-9tegcrc3 438 35 - - HYPH cord-285647-9tegcrc3 438 36 path path NN cord-285647-9tegcrc3 438 37 Laplacian laplacian JJ cord-285647-9tegcrc3 438 38 operators operator NNS cord-285647-9tegcrc3 438 39 , , , cord-285647-9tegcrc3 438 40 71 71 CD cord-285647-9tegcrc3 438 41 where where WRB cord-285647-9tegcrc3 438 42 L L NNP cord-285647-9tegcrc3 438 43 d d NNP cord-285647-9tegcrc3 438 44 is be VBZ cord-285647-9tegcrc3 438 45 a a DT cord-285647-9tegcrc3 438 46 generalization generalization NN cord-285647-9tegcrc3 438 47 of of IN cord-285647-9tegcrc3 438 48 the the DT cord-285647-9tegcrc3 438 49 graph graph NN cord-285647-9tegcrc3 438 50 Laplacian Laplacian NNP cord-285647-9tegcrc3 438 51 operator operator NN cord-285647-9tegcrc3 438 52 to to TO cord-285647-9tegcrc3 438 53 account account VB cord-285647-9tegcrc3 438 54 for for IN cord-285647-9tegcrc3 438 55 long long JJ cord-285647-9tegcrc3 438 56 - - HYPH cord-285647-9tegcrc3 438 57 range range NN cord-285647-9tegcrc3 438 58 hops hop NNS cord-285647-9tegcrc3 438 59 between between IN cord-285647-9tegcrc3 438 60 nodes node NNS cord-285647-9tegcrc3 438 61 in in IN cord-285647-9tegcrc3 438 62 a a DT cord-285647-9tegcrc3 438 63 graph graph NN cord-285647-9tegcrc3 438 64 , , , cord-285647-9tegcrc3 438 65 d d NNP cord-285647-9tegcrc3 438 66 is be VBZ cord-285647-9tegcrc3 438 67 the the DT cord-285647-9tegcrc3 438 68 shortest short JJS cord-285647-9tegcrc3 438 69 path path NN cord-285647-9tegcrc3 438 70 distance distance NN cord-285647-9tegcrc3 438 71 between between IN cord-285647-9tegcrc3 438 72 two two CD cord-285647-9tegcrc3 438 73 nodes node NNS cord-285647-9tegcrc3 438 74 , , , cord-285647-9tegcrc3 438 75 and and CC cord-285647-9tegcrc3 438 76 s s NN cord-285647-9tegcrc3 438 77 > > XX cord-285647-9tegcrc3 438 78 0 0 NFP cord-285647-9tegcrc3 438 79 is be VBZ cord-285647-9tegcrc3 438 80 a a DT cord-285647-9tegcrc3 438 81 parameter parameter NN cord-285647-9tegcrc3 438 82 . . . cord-285647-9tegcrc3 439 1 This this DT cord-285647-9tegcrc3 439 2 equation equation NN cord-285647-9tegcrc3 439 3 has have VBZ cord-285647-9tegcrc3 439 4 never never RB cord-285647-9tegcrc3 439 5 been be VBN cord-285647-9tegcrc3 439 6 used use VBN cord-285647-9tegcrc3 439 7 before before IN cord-285647-9tegcrc3 439 8 except except IN cord-285647-9tegcrc3 439 9 that that DT cord-285647-9tegcrc3 439 10 for for IN cord-285647-9tegcrc3 439 11 the the DT cord-285647-9tegcrc3 439 12 case case NN cord-285647-9tegcrc3 439 13 α α NN cord-285647-9tegcrc3 439 14 = = SYM cord-285647-9tegcrc3 439 15 1 1 CD cord-285647-9tegcrc3 439 16 where where WRB cord-285647-9tegcrc3 439 17 superdiffusive superdiffusive JJ cord-285647-9tegcrc3 439 18 behavior behavior NN cord-285647-9tegcrc3 439 19 was be VBD cord-285647-9tegcrc3 439 20 proved prove VBN cord-285647-9tegcrc3 439 21 in in IN cord-285647-9tegcrc3 439 22 1-and 1-and CD cord-285647-9tegcrc3 439 23 Chaos Chaos NNP cord-285647-9tegcrc3 439 24 ARTICLE article NN cord-285647-9tegcrc3 439 25 scitation.org/journal/cha scitation.org/journal/cha : cord-285647-9tegcrc3 439 26 2-dimensional 2-dimensional JJ cord-285647-9tegcrc3 439 27 cases case NNS cord-285647-9tegcrc3 439 28 . . . cord-285647-9tegcrc3 440 1 72 72 CD cord-285647-9tegcrc3 440 2 , , , cord-285647-9tegcrc3 440 3 73 73 CD cord-285647-9tegcrc3 440 4 Other other JJ cord-285647-9tegcrc3 440 5 approaches approach NNS cord-285647-9tegcrc3 440 6 have have VBP cord-285647-9tegcrc3 440 7 also also RB cord-285647-9tegcrc3 440 8 been be VBN cord-285647-9tegcrc3 440 9 recently recently RB cord-285647-9tegcrc3 440 10 used use VBN cord-285647-9tegcrc3 440 11 for for IN cord-285647-9tegcrc3 440 12 similar similar JJ cord-285647-9tegcrc3 440 13 purposes purpose NNS cord-285647-9tegcrc3 440 14 in in IN cord-285647-9tegcrc3 440 15 the the DT cord-285647-9tegcrc3 440 16 literature literature NN cord-285647-9tegcrc3 440 17 . . . cord-285647-9tegcrc3 441 1 74 74 CD cord-285647-9tegcrc3 442 1 We -PRON- PRP cord-285647-9tegcrc3 442 2 then then RB cord-285647-9tegcrc3 442 3 hope hope VBP cord-285647-9tegcrc3 442 4 that that IN cord-285647-9tegcrc3 442 5 the the DT cord-285647-9tegcrc3 442 6 combination combination NN cord-285647-9tegcrc3 442 7 of of IN cord-285647-9tegcrc3 442 8 metaplexes metaplexes NNP cord-285647-9tegcrc3 442 9 and and CC cord-285647-9tegcrc3 442 10 timeand timeand NN cord-285647-9tegcrc3 442 11 space space NN cord-285647-9tegcrc3 442 12 - - HYPH cord-285647-9tegcrc3 442 13 fractional fractional JJ cord-285647-9tegcrc3 442 14 diffusive diffusive JJ cord-285647-9tegcrc3 442 15 models model NNS cord-285647-9tegcrc3 442 16 do do VBP cord-285647-9tegcrc3 442 17 capture capture VB cord-285647-9tegcrc3 442 18 more more JJR cord-285647-9tegcrc3 442 19 of of IN cord-285647-9tegcrc3 442 20 the the DT cord-285647-9tegcrc3 442 21 details detail NNS cord-285647-9tegcrc3 442 22 of of IN cord-285647-9tegcrc3 442 23 protein protein NN cord-285647-9tegcrc3 442 24 - - HYPH cord-285647-9tegcrc3 442 25 protein protein NN cord-285647-9tegcrc3 442 26 interactions interaction NNS cord-285647-9tegcrc3 442 27 in in IN cord-285647-9tegcrc3 442 28 crowded crowd VBN cord-285647-9tegcrc3 442 29 cellular cellular JJ cord-285647-9tegcrc3 442 30 environments environment NNS cord-285647-9tegcrc3 442 31 . . . cord-285647-9tegcrc3 443 1 See see VB cord-285647-9tegcrc3 443 2 the the DT cord-285647-9tegcrc3 443 3 supplementary supplementary JJ cord-285647-9tegcrc3 443 4 material material NN cord-285647-9tegcrc3 443 5 for for IN cord-285647-9tegcrc3 443 6 a a DT cord-285647-9tegcrc3 443 7 list list NN cord-285647-9tegcrc3 443 8 of of IN cord-285647-9tegcrc3 443 9 proteins protein NNS cord-285647-9tegcrc3 443 10 targeted target VBN cord-285647-9tegcrc3 443 11 by by IN cord-285647-9tegcrc3 443 12 SARS SARS NNP cord-285647-9tegcrc3 443 13 - - HYPH cord-285647-9tegcrc3 443 14 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 443 15 , , , cord-285647-9tegcrc3 443 16 which which WDT cord-285647-9tegcrc3 443 17 are be VBP cord-285647-9tegcrc3 443 18 found find VBN cord-285647-9tegcrc3 443 19 in in IN cord-285647-9tegcrc3 443 20 the the DT cord-285647-9tegcrc3 443 21 database database NN cord-285647-9tegcrc3 443 22 DisGeNet DisGeNet VBZ cord-285647-9tegcrc3 443 23 as as IN cord-285647-9tegcrc3 443 24 displaying display VBG cord-285647-9tegcrc3 443 25 " " `` cord-285647-9tegcrc3 443 26 definitive definitive JJ cord-285647-9tegcrc3 443 27 " " '' cord-285647-9tegcrc3 443 28 or or CC cord-285647-9tegcrc3 443 29 " " `` cord-285647-9tegcrc3 443 30 strong strong JJ cord-285647-9tegcrc3 443 31 " " '' cord-285647-9tegcrc3 443 32 evidence evidence NN cord-285647-9tegcrc3 443 33 of of IN cord-285647-9tegcrc3 443 34 participating participate VBG cord-285647-9tegcrc3 443 35 in in IN cord-285647-9tegcrc3 443 36 human human JJ cord-285647-9tegcrc3 443 37 diseases disease NNS cord-285647-9tegcrc3 443 38 . . . cord-285647-9tegcrc3 444 1 The the DT cord-285647-9tegcrc3 444 2 Disease Disease NNP cord-285647-9tegcrc3 444 3 ID ID NNP cord-285647-9tegcrc3 444 4 is be VBZ cord-285647-9tegcrc3 444 5 the the DT cord-285647-9tegcrc3 444 6 code code NN cord-285647-9tegcrc3 444 7 of of IN cord-285647-9tegcrc3 444 8 the the DT cord-285647-9tegcrc3 444 9 disease disease NN cord-285647-9tegcrc3 444 10 in in IN cord-285647-9tegcrc3 444 11 DisGeNet disgenet NN cord-285647-9tegcrc3 444 12 . . . cord-285647-9tegcrc3 445 1 A a DT cord-285647-9tegcrc3 445 2 list list NN cord-285647-9tegcrc3 445 3 of of IN cord-285647-9tegcrc3 445 4 proteins protein NNS cord-285647-9tegcrc3 445 5 with with IN cord-285647-9tegcrc3 445 6 the the DT cord-285647-9tegcrc3 445 7 largest large JJS cord-285647-9tegcrc3 445 8 effect effect NN cord-285647-9tegcrc3 445 9 on on IN cord-285647-9tegcrc3 445 10 perturbing perturb VBG cord-285647-9tegcrc3 445 11 those those DT cord-285647-9tegcrc3 445 12 38 38 CD cord-285647-9tegcrc3 445 13 proteins protein NNS cord-285647-9tegcrc3 445 14 are be VBP cord-285647-9tegcrc3 445 15 identified identify VBN cord-285647-9tegcrc3 445 16 in in IN cord-285647-9tegcrc3 445 17 human human JJ cord-285647-9tegcrc3 445 18 diseases disease NNS cord-285647-9tegcrc3 445 19 . . . cord-285647-9tegcrc3 446 1 p p NN cord-285647-9tegcrc3 446 2 tot tot NN cord-285647-9tegcrc3 446 3 is be VBZ cord-285647-9tegcrc3 446 4 the the DT cord-285647-9tegcrc3 446 5 sum sum NN cord-285647-9tegcrc3 446 6 of of IN cord-285647-9tegcrc3 446 7 the the DT cord-285647-9tegcrc3 446 8 probabilities probability NNS cord-285647-9tegcrc3 446 9 that that WDT cord-285647-9tegcrc3 446 10 the the DT cord-285647-9tegcrc3 446 11 given give VBN cord-285647-9tegcrc3 446 12 protein protein NN cord-285647-9tegcrc3 446 13 activates activate VBZ cord-285647-9tegcrc3 446 14 those those DT cord-285647-9tegcrc3 446 15 identified identify VBN cord-285647-9tegcrc3 446 16 as as IN cord-285647-9tegcrc3 446 17 having have VBG cord-285647-9tegcrc3 446 18 " " `` cord-285647-9tegcrc3 446 19 definitive definitive JJ cord-285647-9tegcrc3 446 20 " " '' cord-285647-9tegcrc3 446 21 or or CC cord-285647-9tegcrc3 446 22 " " `` cord-285647-9tegcrc3 446 23 strong strong JJ cord-285647-9tegcrc3 446 24 " " '' cord-285647-9tegcrc3 446 25 evidence evidence NN cord-285647-9tegcrc3 446 26 of of IN cord-285647-9tegcrc3 446 27 being be VBG cord-285647-9tegcrc3 446 28 involved involve VBN cord-285647-9tegcrc3 446 29 in in IN cord-285647-9tegcrc3 446 30 a a DT cord-285647-9tegcrc3 446 31 human human JJ cord-285647-9tegcrc3 446 32 disease disease NN cord-285647-9tegcrc3 446 33 . . . cord-285647-9tegcrc3 447 1 There there EX cord-285647-9tegcrc3 447 2 is be VBZ cord-285647-9tegcrc3 447 3 an an DT cord-285647-9tegcrc3 447 4 RNA RNA NNP cord-285647-9tegcrc3 447 5 expression expression NN cord-285647-9tegcrc3 447 6 overview overview NN cord-285647-9tegcrc3 447 7 for for IN cord-285647-9tegcrc3 447 8 proteins protein NNS cord-285647-9tegcrc3 447 9 targeted target VBN cord-285647-9tegcrc3 447 10 by by IN cord-285647-9tegcrc3 447 11 SARS SARS NNP cord-285647-9tegcrc3 447 12 - - HYPH cord-285647-9tegcrc3 447 13 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 447 14 and and CC cord-285647-9tegcrc3 447 15 mainly mainly RB cord-285647-9tegcrc3 447 16 expressed express VBN cord-285647-9tegcrc3 447 17 outside outside IN cord-285647-9tegcrc3 447 18 the the DT cord-285647-9tegcrc3 447 19 lungs lung NNS cord-285647-9tegcrc3 447 20 . . . cord-285647-9tegcrc3 448 1 We -PRON- PRP cord-285647-9tegcrc3 448 2 select select VBP cord-285647-9tegcrc3 448 3 the the DT cord-285647-9tegcrc3 448 4 top top JJ cord-285647-9tegcrc3 448 5 RNA RNA NNP cord-285647-9tegcrc3 448 6 expressions expression NNS cord-285647-9tegcrc3 448 7 in in IN cord-285647-9tegcrc3 448 8 the the DT cord-285647-9tegcrc3 448 9 four four CD cord-285647-9tegcrc3 448 10 databases database NNS cord-285647-9tegcrc3 448 11 reported report VBN cord-285647-9tegcrc3 448 12 in in IN cord-285647-9tegcrc3 448 13 The the DT cord-285647-9tegcrc3 448 14 Human Human NNP cord-285647-9tegcrc3 448 15 Protein Protein NNP cord-285647-9tegcrc3 448 16 Atlas Atlas NNP cord-285647-9tegcrc3 448 17 . . . cord-285647-9tegcrc3 449 1 There there EX cord-285647-9tegcrc3 449 2 is be VBZ cord-285647-9tegcrc3 449 3 a a DT cord-285647-9tegcrc3 449 4 list list NN cord-285647-9tegcrc3 449 5 of of IN cord-285647-9tegcrc3 449 6 proteins protein NNS cord-285647-9tegcrc3 449 7 mainly mainly RB cord-285647-9tegcrc3 449 8 expressed express VBN cord-285647-9tegcrc3 449 9 outside outside IN cord-285647-9tegcrc3 449 10 the the DT cord-285647-9tegcrc3 449 11 lungs lung NNS cord-285647-9tegcrc3 449 12 and and CC cord-285647-9tegcrc3 449 13 their -PRON- PRP$ cord-285647-9tegcrc3 449 14 major major JJ cord-285647-9tegcrc3 449 15 activators activator NNS cord-285647-9tegcrc3 449 16 , , , cord-285647-9tegcrc3 449 17 which which WDT cord-285647-9tegcrc3 449 18 are be VBP cord-285647-9tegcrc3 449 19 proteins protein NNS cord-285647-9tegcrc3 449 20 mainly mainly RB cord-285647-9tegcrc3 449 21 expressed express VBN cord-285647-9tegcrc3 449 22 in in IN cord-285647-9tegcrc3 449 23 the the DT cord-285647-9tegcrc3 449 24 lungs lung NNS cord-285647-9tegcrc3 449 25 . . . cord-285647-9tegcrc3 450 1 The the DT cord-285647-9tegcrc3 450 2 author author NN cord-285647-9tegcrc3 450 3 thanks thank NNS cord-285647-9tegcrc3 450 4 Dr. Dr. NNP cord-285647-9tegcrc3 450 5 Deisy Deisy NNP cord-285647-9tegcrc3 450 6 Morselli Morselli NNP cord-285647-9tegcrc3 450 7 Gysi Gysi NNP cord-285647-9tegcrc3 450 8 for for IN cord-285647-9tegcrc3 450 9 sharing share VBG cord-285647-9tegcrc3 450 10 data datum NNS cord-285647-9tegcrc3 450 11 and and CC cord-285647-9tegcrc3 450 12 information information NN cord-285647-9tegcrc3 450 13 . . . cord-285647-9tegcrc3 451 1 The the DT cord-285647-9tegcrc3 451 2 author author NN cord-285647-9tegcrc3 451 3 is be VBZ cord-285647-9tegcrc3 451 4 indebted indebte VBN cord-285647-9tegcrc3 451 5 to to IN cord-285647-9tegcrc3 451 6 two two CD cord-285647-9tegcrc3 451 7 anonymous anonymous JJ cord-285647-9tegcrc3 451 8 referees referee NNS cord-285647-9tegcrc3 451 9 whose whose WP$ cord-285647-9tegcrc3 451 10 clever clever JJ cord-285647-9tegcrc3 451 11 comments comment NNS cord-285647-9tegcrc3 451 12 helped help VBD cord-285647-9tegcrc3 451 13 in in IN cord-285647-9tegcrc3 451 14 improving improve VBG cord-285647-9tegcrc3 451 15 this this DT cord-285647-9tegcrc3 451 16 work work NN cord-285647-9tegcrc3 451 17 substantially substantially RB cord-285647-9tegcrc3 451 18 . . . cord-285647-9tegcrc3 452 1 The the DT cord-285647-9tegcrc3 452 2 data datum NNS cord-285647-9tegcrc3 452 3 that that WDT cord-285647-9tegcrc3 452 4 support support VBP cord-285647-9tegcrc3 452 5 the the DT cord-285647-9tegcrc3 452 6 findings finding NNS cord-285647-9tegcrc3 452 7 of of IN cord-285647-9tegcrc3 452 8 this this DT cord-285647-9tegcrc3 452 9 study study NN cord-285647-9tegcrc3 452 10 are be VBP cord-285647-9tegcrc3 452 11 available available JJ cord-285647-9tegcrc3 452 12 within within IN cord-285647-9tegcrc3 452 13 the the DT cord-285647-9tegcrc3 452 14 article article NN cord-285647-9tegcrc3 452 15 and and CC cord-285647-9tegcrc3 452 16 its -PRON- PRP$ cord-285647-9tegcrc3 452 17 supplementary supplementary JJ cord-285647-9tegcrc3 452 18 material material NN cord-285647-9tegcrc3 452 19 and and CC cord-285647-9tegcrc3 452 20 also also RB cord-285647-9tegcrc3 452 21 from from IN cord-285647-9tegcrc3 452 22 the the DT cord-285647-9tegcrc3 452 23 corresponding correspond VBG cord-285647-9tegcrc3 452 24 author author NN cord-285647-9tegcrc3 452 25 upon upon IN cord-285647-9tegcrc3 452 26 reasonable reasonable JJ cord-285647-9tegcrc3 452 27 request request NN cord-285647-9tegcrc3 452 28 . . . cord-285647-9tegcrc3 453 1 scitation.org/journal/cha scitation.org/journal/cha UH cord-285647-9tegcrc3 454 1 The the DT cord-285647-9tegcrc3 454 2 species specie NNS cord-285647-9tegcrc3 454 3 severe severe JJ cord-285647-9tegcrc3 454 4 acute acute JJ cord-285647-9tegcrc3 454 5 respiratory respiratory JJ cord-285647-9tegcrc3 454 6 syndrome syndrome NN cord-285647-9tegcrc3 454 7 - - HYPH cord-285647-9tegcrc3 454 8 related relate VBN cord-285647-9tegcrc3 454 9 coronavirus coronavirus NN cord-285647-9tegcrc3 454 10 : : : cord-285647-9tegcrc3 454 11 Classifying classify VBG cord-285647-9tegcrc3 454 12 2019-nCoV 2019-ncov CD cord-285647-9tegcrc3 454 13 and and CC cord-285647-9tegcrc3 454 14 naming name VBG cord-285647-9tegcrc3 454 15 it -PRON- PRP cord-285647-9tegcrc3 454 16 SARS SARS NNP cord-285647-9tegcrc3 454 17 - - HYPH cord-285647-9tegcrc3 454 18 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 455 1 A a DT cord-285647-9tegcrc3 455 2 pneumonia pneumonia NN cord-285647-9tegcrc3 455 3 outbreak outbreak NN cord-285647-9tegcrc3 455 4 associated associate VBN cord-285647-9tegcrc3 455 5 with with IN cord-285647-9tegcrc3 455 6 a a DT cord-285647-9tegcrc3 455 7 new new JJ cord-285647-9tegcrc3 455 8 coronavirus coronavirus NN cord-285647-9tegcrc3 455 9 of of IN cord-285647-9tegcrc3 455 10 probable probable JJ cord-285647-9tegcrc3 455 11 bat bat NN cord-285647-9tegcrc3 455 12 origin origin NN cord-285647-9tegcrc3 456 1 A a DT cord-285647-9tegcrc3 456 2 new new JJ cord-285647-9tegcrc3 456 3 coronavirus coronavirus NN cord-285647-9tegcrc3 456 4 associated associate VBN cord-285647-9tegcrc3 456 5 with with IN cord-285647-9tegcrc3 456 6 human human JJ cord-285647-9tegcrc3 456 7 respiratory respiratory JJ cord-285647-9tegcrc3 456 8 disease disease NN cord-285647-9tegcrc3 456 9 in in IN cord-285647-9tegcrc3 456 10 china china NNP cord-285647-9tegcrc3 456 11 Review Review NNP cord-285647-9tegcrc3 456 12 of of IN cord-285647-9tegcrc3 456 13 the the DT cord-285647-9tegcrc3 456 14 clinical clinical JJ cord-285647-9tegcrc3 456 15 characteristics characteristic NNS cord-285647-9tegcrc3 456 16 of of IN cord-285647-9tegcrc3 456 17 coronavirus coronavirus NN cord-285647-9tegcrc3 456 18 disease disease NN cord-285647-9tegcrc3 456 19 2019 2019 CD cord-285647-9tegcrc3 456 20 ( ( -LRB- cord-285647-9tegcrc3 456 21 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 456 22 ) ) -RRB- cord-285647-9tegcrc3 456 23 Coronavirus Coronavirus NNP cord-285647-9tegcrc3 456 24 disease disease NN cord-285647-9tegcrc3 456 25 2019 2019 CD cord-285647-9tegcrc3 456 26 ( ( -LRB- cord-285647-9tegcrc3 456 27 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 456 28 ) ) -RRB- cord-285647-9tegcrc3 456 29 : : : cord-285647-9tegcrc3 456 30 A a DT cord-285647-9tegcrc3 456 31 clinical clinical JJ cord-285647-9tegcrc3 456 32 update update NN cord-285647-9tegcrc3 456 33 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 456 34 and and CC cord-285647-9tegcrc3 456 35 multi multi JJ cord-285647-9tegcrc3 456 36 - - JJ cord-285647-9tegcrc3 456 37 organ organ JJ cord-285647-9tegcrc3 456 38 response response NN cord-285647-9tegcrc3 457 1 Genomic genomic JJ cord-285647-9tegcrc3 457 2 characterization characterization NN cord-285647-9tegcrc3 457 3 of of IN cord-285647-9tegcrc3 457 4 the the DT cord-285647-9tegcrc3 457 5 2019 2019 CD cord-285647-9tegcrc3 457 6 novel novel NN cord-285647-9tegcrc3 457 7 human human NN cord-285647-9tegcrc3 457 8 - - HYPH cord-285647-9tegcrc3 457 9 pathogenic pathogenic JJ cord-285647-9tegcrc3 457 10 coronavirus coronavirus NN cord-285647-9tegcrc3 457 11 isolated isolate VBN cord-285647-9tegcrc3 457 12 from from IN cord-285647-9tegcrc3 457 13 a a DT cord-285647-9tegcrc3 457 14 patient patient NN cord-285647-9tegcrc3 457 15 with with IN cord-285647-9tegcrc3 457 16 atypical atypical JJ cord-285647-9tegcrc3 457 17 pneumonia pneumonia NN cord-285647-9tegcrc3 457 18 after after IN cord-285647-9tegcrc3 457 19 visiting visit VBG cord-285647-9tegcrc3 457 20 Wuhan Wuhan NNP cord-285647-9tegcrc3 457 21 Angiotensin Angiotensin NNP cord-285647-9tegcrc3 457 22 - - HYPH cord-285647-9tegcrc3 457 23 converting convert VBG cord-285647-9tegcrc3 457 24 enzyme enzyme NN cord-285647-9tegcrc3 457 25 2 2 CD cord-285647-9tegcrc3 457 26 is be VBZ cord-285647-9tegcrc3 457 27 a a DT cord-285647-9tegcrc3 457 28 functional functional JJ cord-285647-9tegcrc3 457 29 receptor receptor NN cord-285647-9tegcrc3 457 30 for for IN cord-285647-9tegcrc3 457 31 the the DT cord-285647-9tegcrc3 457 32 SARS SARS NNP cord-285647-9tegcrc3 457 33 coronavirus coronavirus NN cord-285647-9tegcrc3 457 34 SARS SARS NNP cord-285647-9tegcrc3 457 35 - - HYPH cord-285647-9tegcrc3 457 36 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 457 37 cell cell NN cord-285647-9tegcrc3 457 38 entry entry NN cord-285647-9tegcrc3 457 39 depends depend VBZ cord-285647-9tegcrc3 457 40 on on IN cord-285647-9tegcrc3 457 41 ACE2 ACE2 NNP cord-285647-9tegcrc3 457 42 and and CC cord-285647-9tegcrc3 457 43 TMPRSS2 TMPRSS2 NNP cord-285647-9tegcrc3 457 44 and and CC cord-285647-9tegcrc3 457 45 is be VBZ cord-285647-9tegcrc3 457 46 blocked block VBN cord-285647-9tegcrc3 457 47 by by IN cord-285647-9tegcrc3 457 48 a a DT cord-285647-9tegcrc3 457 49 clinically clinically RB cord-285647-9tegcrc3 457 50 proven prove VBN cord-285647-9tegcrc3 457 51 protease protease NN cord-285647-9tegcrc3 457 52 inhibitor inhibitor NN cord-285647-9tegcrc3 457 53 Specific Specific NNP cord-285647-9tegcrc3 457 54 ACE2 ACE2 NNP cord-285647-9tegcrc3 457 55 expression expression NN cord-285647-9tegcrc3 457 56 in in IN cord-285647-9tegcrc3 457 57 cholangiocytes cholangiocyte NNS cord-285647-9tegcrc3 457 58 may may MD cord-285647-9tegcrc3 457 59 cause cause VB cord-285647-9tegcrc3 457 60 liver liver NN cord-285647-9tegcrc3 457 61 damage damage NN cord-285647-9tegcrc3 457 62 after after IN cord-285647-9tegcrc3 457 63 2019-nCoV 2019-ncov CD cord-285647-9tegcrc3 457 64 infection infection NN cord-285647-9tegcrc3 457 65 Single single JJ cord-285647-9tegcrc3 457 66 - - HYPH cord-285647-9tegcrc3 457 67 cell cell NN cord-285647-9tegcrc3 457 68 RNA rna NN cord-285647-9tegcrc3 457 69 expression expression NN cord-285647-9tegcrc3 457 70 profiling profiling NN cord-285647-9tegcrc3 457 71 of of IN cord-285647-9tegcrc3 457 72 ACE2 ACE2 NNP cord-285647-9tegcrc3 457 73 , , , cord-285647-9tegcrc3 457 74 the the DT cord-285647-9tegcrc3 457 75 putative putative JJ cord-285647-9tegcrc3 457 76 receptor receptor NN cord-285647-9tegcrc3 457 77 of of IN cord-285647-9tegcrc3 457 78 Wuhan Wuhan NNP cord-285647-9tegcrc3 457 79 2019-nCov 2019-ncov CD cord-285647-9tegcrc3 457 80 Tissue tissue NN cord-285647-9tegcrc3 457 81 distribution distribution NN cord-285647-9tegcrc3 457 82 of of IN cord-285647-9tegcrc3 457 83 ACE2 ACE2 NNP cord-285647-9tegcrc3 457 84 protein protein NN cord-285647-9tegcrc3 457 85 , , , cord-285647-9tegcrc3 457 86 the the DT cord-285647-9tegcrc3 457 87 functional functional JJ cord-285647-9tegcrc3 457 88 receptor receptor NN cord-285647-9tegcrc3 457 89 for for IN cord-285647-9tegcrc3 457 90 SARS SARS NNP cord-285647-9tegcrc3 457 91 coronavirus coronavirus NN cord-285647-9tegcrc3 457 92 . . . cord-285647-9tegcrc3 458 1 A a DT cord-285647-9tegcrc3 458 2 first first JJ cord-285647-9tegcrc3 458 3 step step NN cord-285647-9tegcrc3 458 4 in in IN cord-285647-9tegcrc3 458 5 understanding understand VBG cord-285647-9tegcrc3 458 6 SARS SARS NNP cord-285647-9tegcrc3 458 7 pathogenesis pathogenesis NN cord-285647-9tegcrc3 459 1 A a DT cord-285647-9tegcrc3 459 2 SARS SARS NNP cord-285647-9tegcrc3 459 3 - - HYPH cord-285647-9tegcrc3 459 4 CoV-2-human CoV-2-human NNP cord-285647-9tegcrc3 459 5 protein protein NN cord-285647-9tegcrc3 459 6 - - HYPH cord-285647-9tegcrc3 459 7 protein protein NN cord-285647-9tegcrc3 459 8 interaction interaction NN cord-285647-9tegcrc3 459 9 map map NN cord-285647-9tegcrc3 459 10 reveals reveal VBZ cord-285647-9tegcrc3 459 11 drug drug NN cord-285647-9tegcrc3 459 12 targets target NNS cord-285647-9tegcrc3 459 13 and and CC cord-285647-9tegcrc3 459 14 potential potential JJ cord-285647-9tegcrc3 459 15 drug drug NN cord-285647-9tegcrc3 459 16 - - HYPH cord-285647-9tegcrc3 459 17 repurposing repurpose VBG cord-285647-9tegcrc3 459 18 Network Network NNP cord-285647-9tegcrc3 459 19 medicine medicine NN cord-285647-9tegcrc3 459 20 framework framework NN cord-285647-9tegcrc3 459 21 for for IN cord-285647-9tegcrc3 459 22 identifying identify VBG cord-285647-9tegcrc3 459 23 drug drug NN cord-285647-9tegcrc3 459 24 repurposing repurpose VBG cord-285647-9tegcrc3 459 25 opportunities opportunity NNS cord-285647-9tegcrc3 459 26 for for IN cord-285647-9tegcrc3 459 27 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 459 28 Specificity Specificity NNP cord-285647-9tegcrc3 459 29 and and CC cord-285647-9tegcrc3 459 30 stability stability NN cord-285647-9tegcrc3 459 31 in in IN cord-285647-9tegcrc3 459 32 topology topology NN cord-285647-9tegcrc3 459 33 of of IN cord-285647-9tegcrc3 459 34 protein protein NN cord-285647-9tegcrc3 459 35 networks network NNS cord-285647-9tegcrc3 459 36 Perturbation perturbation NN cord-285647-9tegcrc3 459 37 waves wave NNS cord-285647-9tegcrc3 459 38 in in IN cord-285647-9tegcrc3 459 39 proteins protein NNS cord-285647-9tegcrc3 459 40 and and CC cord-285647-9tegcrc3 459 41 protein protein NN cord-285647-9tegcrc3 459 42 networks network NNS cord-285647-9tegcrc3 459 43 : : : cord-285647-9tegcrc3 459 44 Applications application NNS cord-285647-9tegcrc3 459 45 of of IN cord-285647-9tegcrc3 459 46 percolation percolation NN cord-285647-9tegcrc3 459 47 and and CC cord-285647-9tegcrc3 459 48 game game NN cord-285647-9tegcrc3 459 49 theories theory NNS cord-285647-9tegcrc3 459 50 in in IN cord-285647-9tegcrc3 459 51 signaling signal VBG cord-285647-9tegcrc3 459 52 and and CC cord-285647-9tegcrc3 459 53 drug drug NN cord-285647-9tegcrc3 459 54 design design NN cord-285647-9tegcrc3 459 55 Predicting predict VBG cord-285647-9tegcrc3 459 56 perturbation perturbation NN cord-285647-9tegcrc3 459 57 patterns pattern NNS cord-285647-9tegcrc3 459 58 from from IN cord-285647-9tegcrc3 459 59 the the DT cord-285647-9tegcrc3 459 60 topology topology NN cord-285647-9tegcrc3 459 61 of of IN cord-285647-9tegcrc3 459 62 biological biological JJ cord-285647-9tegcrc3 459 63 networks network NNS cord-285647-9tegcrc3 459 64 Modeling model VBG cord-285647-9tegcrc3 459 65 and and CC cord-285647-9tegcrc3 459 66 simulating simulate VBG cord-285647-9tegcrc3 459 67 networks network NNS cord-285647-9tegcrc3 459 68 of of IN cord-285647-9tegcrc3 459 69 interdependent interdependent JJ cord-285647-9tegcrc3 459 70 protein protein NN cord-285647-9tegcrc3 459 71 interactions interaction NNS cord-285647-9tegcrc3 459 72 Network Network NNP cord-285647-9tegcrc3 459 73 medicine medicine NN cord-285647-9tegcrc3 459 74 : : : cord-285647-9tegcrc3 459 75 A a DT cord-285647-9tegcrc3 459 76 networkbased networkbased JJ cord-285647-9tegcrc3 459 77 approach approach NN cord-285647-9tegcrc3 459 78 to to IN cord-285647-9tegcrc3 459 79 human human JJ cord-285647-9tegcrc3 459 80 disease disease NN cord-285647-9tegcrc3 459 81 Protein Protein NNP cord-285647-9tegcrc3 459 82 interaction interaction NN cord-285647-9tegcrc3 459 83 networks network NNS cord-285647-9tegcrc3 459 84 in in IN cord-285647-9tegcrc3 459 85 medicine medicine NN cord-285647-9tegcrc3 459 86 and and CC cord-285647-9tegcrc3 459 87 disease disease NN cord-285647-9tegcrc3 459 88 Human human JJ cord-285647-9tegcrc3 459 89 diseases disease NNS cord-285647-9tegcrc3 459 90 through through IN cord-285647-9tegcrc3 459 91 the the DT cord-285647-9tegcrc3 459 92 lens lens NN cord-285647-9tegcrc3 459 93 of of IN cord-285647-9tegcrc3 459 94 network network NN cord-285647-9tegcrc3 459 95 biology biology NN cord-285647-9tegcrc3 459 96 Stochastic stochastic JJ cord-285647-9tegcrc3 459 97 model model NN cord-285647-9tegcrc3 459 98 of of IN cord-285647-9tegcrc3 459 99 protein protein NN cord-285647-9tegcrc3 459 100 - - HYPH cord-285647-9tegcrc3 459 101 protein protein NN cord-285647-9tegcrc3 459 102 interaction interaction NN cord-285647-9tegcrc3 459 103 : : : cord-285647-9tegcrc3 459 104 Why why WRB cord-285647-9tegcrc3 459 105 signaling signal VBG cord-285647-9tegcrc3 459 106 proteins protein NNS cord-285647-9tegcrc3 459 107 need need VBP cord-285647-9tegcrc3 459 108 to to TO cord-285647-9tegcrc3 459 109 be be VB cord-285647-9tegcrc3 459 110 colocalized colocalize VBN cord-285647-9tegcrc3 459 111 Accounting Accounting NNP cord-285647-9tegcrc3 459 112 for for IN cord-285647-9tegcrc3 459 113 conformational conformational JJ cord-285647-9tegcrc3 459 114 changes change NNS cord-285647-9tegcrc3 459 115 during during IN cord-285647-9tegcrc3 459 116 protein protein NN cord-285647-9tegcrc3 459 117 - - HYPH cord-285647-9tegcrc3 459 118 protein protein NN cord-285647-9tegcrc3 459 119 docking docking NN cord-285647-9tegcrc3 460 1 Inferring infer VBG cord-285647-9tegcrc3 460 2 novel novel JJ cord-285647-9tegcrc3 460 3 tumor tumor NN cord-285647-9tegcrc3 460 4 suppressor suppressor NN cord-285647-9tegcrc3 460 5 genes gene NNS cord-285647-9tegcrc3 460 6 with with IN cord-285647-9tegcrc3 460 7 a a DT cord-285647-9tegcrc3 460 8 protein protein NN cord-285647-9tegcrc3 460 9 - - HYPH cord-285647-9tegcrc3 460 10 protein protein NN cord-285647-9tegcrc3 460 11 interaction interaction NN cord-285647-9tegcrc3 460 12 network network NN cord-285647-9tegcrc3 460 13 and and CC cord-285647-9tegcrc3 460 14 network network NN cord-285647-9tegcrc3 460 15 diffusion diffusion NN cord-285647-9tegcrc3 460 16 algorithms algorithm NNS cord-285647-9tegcrc3 460 17 Information information NN cord-285647-9tegcrc3 460 18 flow flow VBP cord-285647-9tegcrc3 460 19 in in IN cord-285647-9tegcrc3 460 20 interaction interaction NN cord-285647-9tegcrc3 460 21 networks network NNS cord-285647-9tegcrc3 460 22 Sampling sample VBG cord-285647-9tegcrc3 460 23 the the DT cord-285647-9tegcrc3 460 24 cell cell NN cord-285647-9tegcrc3 460 25 with with IN cord-285647-9tegcrc3 460 26 anomalous anomalous JJ cord-285647-9tegcrc3 460 27 diffusion- diffusion- NN cord-285647-9tegcrc3 461 1 The the DT cord-285647-9tegcrc3 461 2 discovery discovery NN cord-285647-9tegcrc3 461 3 of of IN cord-285647-9tegcrc3 461 4 slowness slowness NN cord-285647-9tegcrc3 461 5 Understanding understand VBG cord-285647-9tegcrc3 461 6 biochemical biochemical JJ cord-285647-9tegcrc3 461 7 processes process NNS cord-285647-9tegcrc3 461 8 in in IN cord-285647-9tegcrc3 461 9 the the DT cord-285647-9tegcrc3 461 10 presence presence NN cord-285647-9tegcrc3 461 11 of of IN cord-285647-9tegcrc3 461 12 sub sub JJ cord-285647-9tegcrc3 461 13 - - JJ cord-285647-9tegcrc3 461 14 diffusive diffusive JJ cord-285647-9tegcrc3 461 15 behavior behavior NN cord-285647-9tegcrc3 461 16 of of IN cord-285647-9tegcrc3 461 17 biomolecules biomolecule NNS cord-285647-9tegcrc3 461 18 in in IN cord-285647-9tegcrc3 461 19 solution solution NN cord-285647-9tegcrc3 461 20 and and CC cord-285647-9tegcrc3 461 21 living living NN cord-285647-9tegcrc3 461 22 cells cell NNS cord-285647-9tegcrc3 461 23 Protein Protein NNP cord-285647-9tegcrc3 461 24 motion motion NN cord-285647-9tegcrc3 461 25 in in IN cord-285647-9tegcrc3 461 26 the the DT cord-285647-9tegcrc3 461 27 nucleus nucleus NN cord-285647-9tegcrc3 461 28 : : : cord-285647-9tegcrc3 461 29 From from IN cord-285647-9tegcrc3 461 30 anomalous anomalous JJ cord-285647-9tegcrc3 461 31 diffusion diffusion NN cord-285647-9tegcrc3 461 32 to to IN cord-285647-9tegcrc3 461 33 weak weak JJ cord-285647-9tegcrc3 461 34 interactions interaction NNS cord-285647-9tegcrc3 461 35 Random random JJ cord-285647-9tegcrc3 461 36 diffusivity diffusivity NN cord-285647-9tegcrc3 461 37 from from IN cord-285647-9tegcrc3 461 38 stochastic stochastic JJ cord-285647-9tegcrc3 461 39 equations equation NNS cord-285647-9tegcrc3 461 40 : : : cord-285647-9tegcrc3 462 1 Comparison comparison NN cord-285647-9tegcrc3 462 2 of of IN cord-285647-9tegcrc3 462 3 two two CD cord-285647-9tegcrc3 462 4 models model NNS cord-285647-9tegcrc3 462 5 of of IN cord-285647-9tegcrc3 462 6 Brownian Brownian NNP cord-285647-9tegcrc3 462 7 yet yet CC cord-285647-9tegcrc3 462 8 non non JJ cord-285647-9tegcrc3 462 9 - - JJ cord-285647-9tegcrc3 462 10 Gaussian gaussian JJ cord-285647-9tegcrc3 462 11 diffusion diffusion NN cord-285647-9tegcrc3 462 12 Anomalous anomalous JJ cord-285647-9tegcrc3 462 13 protein protein NN cord-285647-9tegcrc3 462 14 diffusion diffusion NN cord-285647-9tegcrc3 462 15 in in IN cord-285647-9tegcrc3 462 16 living living NN cord-285647-9tegcrc3 462 17 cells cell NNS cord-285647-9tegcrc3 462 18 as as IN cord-285647-9tegcrc3 462 19 seen see VBN cord-285647-9tegcrc3 462 20 by by IN cord-285647-9tegcrc3 462 21 fluorescence fluorescence NN cord-285647-9tegcrc3 462 22 correlation correlation NN cord-285647-9tegcrc3 462 23 spectroscopy spectroscopy NN cord-285647-9tegcrc3 463 1 Anomalous anomalous JJ cord-285647-9tegcrc3 463 2 subdiffusion subdiffusion NN cord-285647-9tegcrc3 463 3 is be VBZ cord-285647-9tegcrc3 463 4 a a DT cord-285647-9tegcrc3 463 5 measure measure NN cord-285647-9tegcrc3 463 6 for for IN cord-285647-9tegcrc3 463 7 cytoplasmic cytoplasmic JJ cord-285647-9tegcrc3 463 8 crowding crowding NN cord-285647-9tegcrc3 463 9 in in IN cord-285647-9tegcrc3 463 10 living live VBG cord-285647-9tegcrc3 463 11 cell cell NN cord-285647-9tegcrc3 463 12 Elucidating elucidate VBG cord-285647-9tegcrc3 463 13 the the DT cord-285647-9tegcrc3 463 14 origin origin NN cord-285647-9tegcrc3 463 15 of of IN cord-285647-9tegcrc3 463 16 anomalous anomalous JJ cord-285647-9tegcrc3 463 17 diffusion diffusion NN cord-285647-9tegcrc3 463 18 in in IN cord-285647-9tegcrc3 463 19 crowded crowded JJ cord-285647-9tegcrc3 463 20 fluids fluid NNS cord-285647-9tegcrc3 464 1 In in IN cord-285647-9tegcrc3 464 2 a a DT cord-285647-9tegcrc3 464 3 mirror mirror NN cord-285647-9tegcrc3 464 4 dimly dimly RB cord-285647-9tegcrc3 464 5 : : : cord-285647-9tegcrc3 464 6 Tracing trace VBG cord-285647-9tegcrc3 464 7 the the DT cord-285647-9tegcrc3 464 8 movements movement NNS cord-285647-9tegcrc3 464 9 of of IN cord-285647-9tegcrc3 464 10 molecules molecule NNS cord-285647-9tegcrc3 464 11 in in IN cord-285647-9tegcrc3 464 12 living living NN cord-285647-9tegcrc3 464 13 cells cell NNS cord-285647-9tegcrc3 464 14 Protein Protein NNP cord-285647-9tegcrc3 464 15 entrapment entrapment NN cord-285647-9tegcrc3 464 16 in in IN cord-285647-9tegcrc3 464 17 polymeric polymeric JJ cord-285647-9tegcrc3 464 18 mesh mesh NN cord-285647-9tegcrc3 464 19 : : : cord-285647-9tegcrc3 464 20 Diffusion diffusion NN cord-285647-9tegcrc3 464 21 in in IN cord-285647-9tegcrc3 464 22 crowded crowded JJ cord-285647-9tegcrc3 464 23 environment environment NN cord-285647-9tegcrc3 464 24 with with IN cord-285647-9tegcrc3 464 25 fast fast JJ cord-285647-9tegcrc3 464 26 process process NN cord-285647-9tegcrc3 464 27 on on IN cord-285647-9tegcrc3 464 28 short short JJ cord-285647-9tegcrc3 464 29 scales scale NNS cord-285647-9tegcrc3 464 30 From from IN cord-285647-9tegcrc3 464 31 continuous continuous JJ cord-285647-9tegcrc3 464 32 time time NN cord-285647-9tegcrc3 464 33 random random JJ cord-285647-9tegcrc3 464 34 walks walk NNS cord-285647-9tegcrc3 464 35 to to IN cord-285647-9tegcrc3 464 36 fractional fractional JJ cord-285647-9tegcrc3 464 37 Fokker Fokker NNP cord-285647-9tegcrc3 464 38 - - HYPH cord-285647-9tegcrc3 464 39 Planck Planck NNP cord-285647-9tegcrc3 464 40 equation equation NN cord-285647-9tegcrc3 465 1 A a DT cord-285647-9tegcrc3 465 2 mathematical mathematical JJ cord-285647-9tegcrc3 465 3 analysis analysis NN cord-285647-9tegcrc3 465 4 of of IN cord-285647-9tegcrc3 465 5 obstructed obstruct VBN cord-285647-9tegcrc3 465 6 diffusion diffusion NN cord-285647-9tegcrc3 465 7 within within IN cord-285647-9tegcrc3 465 8 skeletal skeletal JJ cord-285647-9tegcrc3 465 9 muscle muscle NN cord-285647-9tegcrc3 465 10 Fractional Fractional NNP cord-285647-9tegcrc3 465 11 Calculus Calculus NNP cord-285647-9tegcrc3 465 12 and and CC cord-285647-9tegcrc3 465 13 Waves Waves NNPS cord-285647-9tegcrc3 465 14 in in IN cord-285647-9tegcrc3 465 15 Linear Linear NNP cord-285647-9tegcrc3 465 16 Viscoelasticity Viscoelasticity NNP cord-285647-9tegcrc3 465 17 . . . cord-285647-9tegcrc3 466 1 An an DT cord-285647-9tegcrc3 466 2 Introduction introduction NN cord-285647-9tegcrc3 466 3 to to IN cord-285647-9tegcrc3 466 4 Mathematical Mathematical NNP cord-285647-9tegcrc3 466 5 Models Models NNPS cord-285647-9tegcrc3 466 6 Distributed distribute VBN cord-285647-9tegcrc3 466 7 coordination coordination NN cord-285647-9tegcrc3 466 8 algorithms algorithm NNS cord-285647-9tegcrc3 466 9 for for IN cord-285647-9tegcrc3 466 10 multiple multiple JJ cord-285647-9tegcrc3 466 11 fractional fractional JJ cord-285647-9tegcrc3 466 12 - - HYPH cord-285647-9tegcrc3 466 13 order order NN cord-285647-9tegcrc3 466 14 systems system NNS cord-285647-9tegcrc3 466 15 Distributed distribute VBN cord-285647-9tegcrc3 466 16 coordination coordination NN cord-285647-9tegcrc3 466 17 of of IN cord-285647-9tegcrc3 466 18 networked networked JJ cord-285647-9tegcrc3 466 19 fractional fractional JJ cord-285647-9tegcrc3 466 20 - - HYPH cord-285647-9tegcrc3 466 21 order order NN cord-285647-9tegcrc3 466 22 systems system NNS cord-285647-9tegcrc3 466 23 Consensus Consensus NNP cord-285647-9tegcrc3 466 24 of of IN cord-285647-9tegcrc3 466 25 networked networked JJ cord-285647-9tegcrc3 466 26 multi multi JJ cord-285647-9tegcrc3 466 27 - - JJ cord-285647-9tegcrc3 466 28 agent agent JJ cord-285647-9tegcrc3 466 29 systems system NNS cord-285647-9tegcrc3 466 30 with with IN cord-285647-9tegcrc3 466 31 delays delay NNS cord-285647-9tegcrc3 466 32 and and CC cord-285647-9tegcrc3 466 33 fractional fractional JJ cord-285647-9tegcrc3 466 34 - - HYPH cord-285647-9tegcrc3 466 35 order order NN cord-285647-9tegcrc3 466 36 dynamics dynamic NNS cord-285647-9tegcrc3 467 1 The the DT cord-285647-9tegcrc3 467 2 random random JJ cord-285647-9tegcrc3 467 3 walk walk NN cord-285647-9tegcrc3 467 4 's 's POS cord-285647-9tegcrc3 467 5 guide guide NN cord-285647-9tegcrc3 467 6 to to IN cord-285647-9tegcrc3 467 7 anomalous anomalous JJ cord-285647-9tegcrc3 467 8 diffusion diffusion NN cord-285647-9tegcrc3 467 9 : : : cord-285647-9tegcrc3 467 10 A a DT cord-285647-9tegcrc3 467 11 fractional fractional JJ cord-285647-9tegcrc3 467 12 dynamics dynamic NNS cord-285647-9tegcrc3 467 13 approach approach VBP cord-285647-9tegcrc3 467 14 Long long JJ cord-285647-9tegcrc3 467 15 - - HYPH cord-285647-9tegcrc3 467 16 range range NN cord-285647-9tegcrc3 467 17 navigation navigation NN cord-285647-9tegcrc3 467 18 on on IN cord-285647-9tegcrc3 467 19 complex complex JJ cord-285647-9tegcrc3 467 20 networks network NNS cord-285647-9tegcrc3 467 21 using use VBG cord-285647-9tegcrc3 467 22 Lévy Lévy NNP cord-285647-9tegcrc3 467 23 random random JJ cord-285647-9tegcrc3 467 24 walks walk NNS cord-285647-9tegcrc3 467 25 Fractional fractional JJ cord-285647-9tegcrc3 467 26 dynamics dynamic NNS cord-285647-9tegcrc3 467 27 on on IN cord-285647-9tegcrc3 467 28 networks network NNS cord-285647-9tegcrc3 468 1 : : : cord-285647-9tegcrc3 468 2 Emergence emergence NN cord-285647-9tegcrc3 468 3 of of IN cord-285647-9tegcrc3 468 4 anomalous anomalous JJ cord-285647-9tegcrc3 468 5 diffusion diffusion NN cord-285647-9tegcrc3 468 6 and and CC cord-285647-9tegcrc3 468 7 Lévy Lévy NNP cord-285647-9tegcrc3 468 8 flights flight NNS cord-285647-9tegcrc3 468 9 Fractional Fractional NNP cord-285647-9tegcrc3 468 10 Dynamics Dynamics NNPS cord-285647-9tegcrc3 468 11 on on IN cord-285647-9tegcrc3 468 12 Networks Networks NNPS cord-285647-9tegcrc3 468 13 and and CC cord-285647-9tegcrc3 468 14 Lattices Lattices NNPS cord-285647-9tegcrc3 468 15 Nonlocal nonlocal JJ cord-285647-9tegcrc3 468 16 network network NN cord-285647-9tegcrc3 468 17 dynamics dynamic NNS cord-285647-9tegcrc3 468 18 via via IN cord-285647-9tegcrc3 468 19 fractional fractional JJ cord-285647-9tegcrc3 468 20 graph graph NN cord-285647-9tegcrc3 468 21 Laplacians Laplacians NNP cord-285647-9tegcrc3 468 22 Diffusion Diffusion NNP cord-285647-9tegcrc3 468 23 maps map VBZ cord-285647-9tegcrc3 468 24 The the DT cord-285647-9tegcrc3 468 25 genotype genotype NN cord-285647-9tegcrc3 468 26 - - HYPH cord-285647-9tegcrc3 468 27 tissue tissue NN cord-285647-9tegcrc3 468 28 expression expression NN cord-285647-9tegcrc3 468 29 ( ( -LRB- cord-285647-9tegcrc3 468 30 GTEx gtex NN cord-285647-9tegcrc3 468 31 ) ) -RRB- cord-285647-9tegcrc3 468 32 project project NN cord-285647-9tegcrc3 468 33 Tissue tissue NN cord-285647-9tegcrc3 468 34 - - HYPH cord-285647-9tegcrc3 468 35 based base VBN cord-285647-9tegcrc3 468 36 map map NN cord-285647-9tegcrc3 468 37 of of IN cord-285647-9tegcrc3 468 38 the the DT cord-285647-9tegcrc3 468 39 human human JJ cord-285647-9tegcrc3 468 40 proteome proteome NN cord-285647-9tegcrc3 468 41 A A NNP cord-285647-9tegcrc3 468 42 promoter promoter NN cord-285647-9tegcrc3 468 43 - - HYPH cord-285647-9tegcrc3 468 44 level level NN cord-285647-9tegcrc3 468 45 mammalian mammalian JJ cord-285647-9tegcrc3 468 46 expression expression NN cord-285647-9tegcrc3 468 47 atlas atlas NNP cord-285647-9tegcrc3 468 48 Convergence Convergence NNP cord-285647-9tegcrc3 468 49 speed speed NN cord-285647-9tegcrc3 468 50 of of IN cord-285647-9tegcrc3 468 51 a a DT cord-285647-9tegcrc3 468 52 fractional fractional JJ cord-285647-9tegcrc3 468 53 order order NN cord-285647-9tegcrc3 468 54 consensus consensus NN cord-285647-9tegcrc3 468 55 algorithm algorithm NN cord-285647-9tegcrc3 468 56 over over IN cord-285647-9tegcrc3 468 57 undirected undirected JJ cord-285647-9tegcrc3 468 58 scale scale NN cord-285647-9tegcrc3 468 59 - - HYPH cord-285647-9tegcrc3 468 60 free free JJ cord-285647-9tegcrc3 468 61 networks network NNS cord-285647-9tegcrc3 469 1 The the DT cord-285647-9tegcrc3 469 2 DisGeNET DisGeNET NNP cord-285647-9tegcrc3 469 3 knowledge knowledge NN cord-285647-9tegcrc3 469 4 platform platform NN cord-285647-9tegcrc3 469 5 for for IN cord-285647-9tegcrc3 469 6 disease disease NN cord-285647-9tegcrc3 469 7 genomics genomic NNS cord-285647-9tegcrc3 469 8 : : : cord-285647-9tegcrc3 470 1 2019 2019 CD cord-285647-9tegcrc3 470 2 update update NN cord-285647-9tegcrc3 470 3 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 470 4 and and CC cord-285647-9tegcrc3 470 5 the the DT cord-285647-9tegcrc3 470 6 heart heart NN cord-285647-9tegcrc3 470 7 Cardiac Cardiac NNP cord-285647-9tegcrc3 470 8 involvement involvement NN cord-285647-9tegcrc3 470 9 in in IN cord-285647-9tegcrc3 470 10 a a DT cord-285647-9tegcrc3 470 11 patient patient NN cord-285647-9tegcrc3 470 12 with with IN cord-285647-9tegcrc3 470 13 coronavirus coronavirus NN cord-285647-9tegcrc3 470 14 disease disease NN cord-285647-9tegcrc3 470 15 2019 2019 CD cord-285647-9tegcrc3 470 16 ( ( -LRB- cord-285647-9tegcrc3 470 17 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 470 18 ) ) -RRB- cord-285647-9tegcrc3 470 19 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 470 20 and and CC cord-285647-9tegcrc3 470 21 the the DT cord-285647-9tegcrc3 470 22 cardiovascular cardiovascular JJ cord-285647-9tegcrc3 470 23 system system NN cord-285647-9tegcrc3 470 24 Coronavirus Coronavirus NNP cord-285647-9tegcrc3 470 25 disease disease NN cord-285647-9tegcrc3 470 26 2019 2019 CD cord-285647-9tegcrc3 470 27 ( ( -LRB- cord-285647-9tegcrc3 470 28 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 470 29 ) ) -RRB- cord-285647-9tegcrc3 470 30 and and CC cord-285647-9tegcrc3 471 1 cardiovascular cardiovascular JJ cord-285647-9tegcrc3 471 2 disease disease NN cord-285647-9tegcrc3 471 3 SARS SARS NNP cord-285647-9tegcrc3 471 4 - - HYPH cord-285647-9tegcrc3 471 5 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 471 6 and and CC cord-285647-9tegcrc3 471 7 the the DT cord-285647-9tegcrc3 471 8 testis testis NN cord-285647-9tegcrc3 471 9 : : : cord-285647-9tegcrc3 471 10 Similarity similarity NN cord-285647-9tegcrc3 471 11 to to IN cord-285647-9tegcrc3 471 12 other other JJ cord-285647-9tegcrc3 471 13 viruses virus NNS cord-285647-9tegcrc3 471 14 and and CC cord-285647-9tegcrc3 471 15 routes route NNS cord-285647-9tegcrc3 471 16 of of IN cord-285647-9tegcrc3 471 17 infection infection NN cord-285647-9tegcrc3 471 18 Rising rise VBG cord-285647-9tegcrc3 471 19 concern concern NN cord-285647-9tegcrc3 471 20 on on IN cord-285647-9tegcrc3 471 21 damaged damaged JJ cord-285647-9tegcrc3 471 22 testis testis NN cord-285647-9tegcrc3 471 23 of of IN cord-285647-9tegcrc3 471 24 COVID-19 covid-19 JJ cord-285647-9tegcrc3 471 25 patients patient NNS cord-285647-9tegcrc3 472 1 The the DT cord-285647-9tegcrc3 472 2 need need NN cord-285647-9tegcrc3 472 3 for for IN cord-285647-9tegcrc3 472 4 urogenital urogenital JJ cord-285647-9tegcrc3 472 5 tract tract NN cord-285647-9tegcrc3 472 6 monitoring monitoring NN cord-285647-9tegcrc3 472 7 in in IN cord-285647-9tegcrc3 472 8 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 472 9 ACE2 ACE2 NNP cord-285647-9tegcrc3 472 10 expression expression NN cord-285647-9tegcrc3 472 11 in in IN cord-285647-9tegcrc3 472 12 kidney kidney NN cord-285647-9tegcrc3 472 13 and and CC cord-285647-9tegcrc3 472 14 testis testis NN cord-285647-9tegcrc3 472 15 may may MD cord-285647-9tegcrc3 472 16 cause cause VB cord-285647-9tegcrc3 472 17 kidney kidney NN cord-285647-9tegcrc3 472 18 and and CC cord-285647-9tegcrc3 472 19 testis testis NN cord-285647-9tegcrc3 472 20 damage damage NN cord-285647-9tegcrc3 472 21 after after IN cord-285647-9tegcrc3 472 22 2019-nCoV 2019-ncov CD cord-285647-9tegcrc3 472 23 infection infection NN cord-285647-9tegcrc3 472 24 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 472 25 , , , cord-285647-9tegcrc3 472 26 angiotensin angiotensin NN cord-285647-9tegcrc3 472 27 receptor receptor NN cord-285647-9tegcrc3 472 28 blockers blocker NNS cord-285647-9tegcrc3 472 29 , , , cord-285647-9tegcrc3 472 30 and and CC cord-285647-9tegcrc3 472 31 the the DT cord-285647-9tegcrc3 472 32 brain brain NN cord-285647-9tegcrc3 472 33 Pulmonary Pulmonary NNP cord-285647-9tegcrc3 472 34 , , , cord-285647-9tegcrc3 472 35 cerebral cerebral JJ cord-285647-9tegcrc3 472 36 , , , cord-285647-9tegcrc3 472 37 and and CC cord-285647-9tegcrc3 472 38 renal renal JJ cord-285647-9tegcrc3 472 39 thromboembolic thromboembolic JJ cord-285647-9tegcrc3 472 40 disease disease NN cord-285647-9tegcrc3 472 41 associated associate VBN cord-285647-9tegcrc3 472 42 with with IN cord-285647-9tegcrc3 472 43 COVID-19 covid-19 JJ cord-285647-9tegcrc3 472 44 infection infection NN cord-285647-9tegcrc3 472 45 A a DT cord-285647-9tegcrc3 472 46 case case NN cord-285647-9tegcrc3 472 47 of of IN cord-285647-9tegcrc3 472 48 coronavirus coronavirus NN cord-285647-9tegcrc3 472 49 disease disease NN cord-285647-9tegcrc3 472 50 2019 2019 CD cord-285647-9tegcrc3 472 51 with with IN cord-285647-9tegcrc3 472 52 concomitant concomitant JJ cord-285647-9tegcrc3 472 53 acute acute JJ cord-285647-9tegcrc3 472 54 cerebral cerebral JJ cord-285647-9tegcrc3 472 55 infarction infarction NN cord-285647-9tegcrc3 472 56 and and CC cord-285647-9tegcrc3 472 57 deep deep JJ cord-285647-9tegcrc3 472 58 vein vein NN cord-285647-9tegcrc3 472 59 thrombosis thrombosis NN cord-285647-9tegcrc3 472 60 Kidney kidney NN cord-285647-9tegcrc3 472 61 involvement involvement NN cord-285647-9tegcrc3 472 62 in in IN cord-285647-9tegcrc3 472 63 COVID-19 covid-19 NN cord-285647-9tegcrc3 472 64 and and CC cord-285647-9tegcrc3 472 65 rationale rationale NN cord-285647-9tegcrc3 472 66 for for IN cord-285647-9tegcrc3 472 67 extracorporeal extracorporeal JJ cord-285647-9tegcrc3 472 68 therapies therapy NNS cord-285647-9tegcrc3 472 69 Acute acute JJ cord-285647-9tegcrc3 472 70 kidney kidney NN cord-285647-9tegcrc3 472 71 injury injury NN cord-285647-9tegcrc3 472 72 in in IN cord-285647-9tegcrc3 472 73 SARS SARS NNP cord-285647-9tegcrc3 472 74 - - HYPH cord-285647-9tegcrc3 472 75 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 472 76 infected infect VBN cord-285647-9tegcrc3 472 77 patients patient NNS cord-285647-9tegcrc3 473 1 Caution caution NN cord-285647-9tegcrc3 473 2 on on IN cord-285647-9tegcrc3 473 3 kidney kidney NN cord-285647-9tegcrc3 473 4 dysfunctions dysfunction NNS cord-285647-9tegcrc3 473 5 of of IN cord-285647-9tegcrc3 473 6 COVID-19 covid-19 CD cord-285647-9tegcrc3 473 7 patients patient NNS cord-285647-9tegcrc3 473 8 Additional additional JJ cord-285647-9tegcrc3 473 9 hypotheses hypothesis NNS cord-285647-9tegcrc3 473 10 about about IN cord-285647-9tegcrc3 473 11 why why WRB cord-285647-9tegcrc3 473 12 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 473 13 is be VBZ cord-285647-9tegcrc3 473 14 milder mild JJR cord-285647-9tegcrc3 473 15 in in IN cord-285647-9tegcrc3 473 16 children child NNS cord-285647-9tegcrc3 473 17 than than IN cord-285647-9tegcrc3 473 18 adults adult NNS cord-285647-9tegcrc3 474 1 The the DT cord-285647-9tegcrc3 474 2 novel novel JJ cord-285647-9tegcrc3 474 3 severe severe JJ cord-285647-9tegcrc3 474 4 acute acute JJ cord-285647-9tegcrc3 474 5 respiratory respiratory JJ cord-285647-9tegcrc3 474 6 syndrome syndrome NN cord-285647-9tegcrc3 474 7 coronavirus coronavirus NN cord-285647-9tegcrc3 474 8 2 2 CD cord-285647-9tegcrc3 475 1 ( ( -LRB- cord-285647-9tegcrc3 475 2 SARS SARS NNP cord-285647-9tegcrc3 475 3 - - HYPH cord-285647-9tegcrc3 475 4 CoV-2 CoV-2 NNP cord-285647-9tegcrc3 475 5 ) ) -RRB- cord-285647-9tegcrc3 475 6 directly directly RB cord-285647-9tegcrc3 475 7 decimates decimate VBZ cord-285647-9tegcrc3 475 8 human human JJ cord-285647-9tegcrc3 475 9 spleens spleen NNS cord-285647-9tegcrc3 475 10 and and CC cord-285647-9tegcrc3 475 11 lymph lymph NN cord-285647-9tegcrc3 475 12 nodes node NNS cord-285647-9tegcrc3 476 1 COVID-19 COVID-19 NNP cord-285647-9tegcrc3 476 2 , , , cord-285647-9tegcrc3 476 3 hypothalamo hypothalamo JJ cord-285647-9tegcrc3 476 4 - - HYPH cord-285647-9tegcrc3 476 5 pituitary pituitary NN cord-285647-9tegcrc3 476 6 - - HYPH cord-285647-9tegcrc3 476 7 adrenal adrenal NN cord-285647-9tegcrc3 476 8 axis axis NN cord-285647-9tegcrc3 476 9 and and CC cord-285647-9tegcrc3 476 10 clinical clinical JJ cord-285647-9tegcrc3 476 11 implications implication NNS cord-285647-9tegcrc3 476 12 Metaplex Metaplex NNP cord-285647-9tegcrc3 476 13 networks network NNS cord-285647-9tegcrc3 476 14 : : : cord-285647-9tegcrc3 477 1 Influence influence NN cord-285647-9tegcrc3 477 2 of of IN cord-285647-9tegcrc3 477 3 the the DT cord-285647-9tegcrc3 477 4 exo exo JJ cord-285647-9tegcrc3 477 5 - - HYPH cord-285647-9tegcrc3 477 6 endo endo NNP cord-285647-9tegcrc3 477 7 structure structure NN cord-285647-9tegcrc3 477 8 of of IN cord-285647-9tegcrc3 477 9 complex complex JJ cord-285647-9tegcrc3 477 10 systems system NNS cord-285647-9tegcrc3 477 11 on on IN cord-285647-9tegcrc3 477 12 diffusion diffusion NN cord-285647-9tegcrc3 477 13 Path path NN cord-285647-9tegcrc3 477 14 Laplacian Laplacian NNP cord-285647-9tegcrc3 477 15 matrices matrix NNS cord-285647-9tegcrc3 477 16 : : : cord-285647-9tegcrc3 477 17 Introduction introduction NN cord-285647-9tegcrc3 477 18 and and CC cord-285647-9tegcrc3 477 19 application application NN cord-285647-9tegcrc3 477 20 to to IN cord-285647-9tegcrc3 477 21 the the DT cord-285647-9tegcrc3 477 22 analysis analysis NN cord-285647-9tegcrc3 477 23 of of IN cord-285647-9tegcrc3 477 24 consensus consensus NN cord-285647-9tegcrc3 477 25 in in IN cord-285647-9tegcrc3 477 26 networks network NNS cord-285647-9tegcrc3 477 27 Path Path NNP cord-285647-9tegcrc3 477 28 Laplacian Laplacian NNP cord-285647-9tegcrc3 477 29 operators operator NNS cord-285647-9tegcrc3 477 30 and and CC cord-285647-9tegcrc3 477 31 superdiffusive superdiffusive JJ cord-285647-9tegcrc3 477 32 processes process NNS cord-285647-9tegcrc3 477 33 on on IN cord-285647-9tegcrc3 477 34 graphs graph NNS cord-285647-9tegcrc3 477 35 . . . cord-285647-9tegcrc3 478 1 I. I. NNP cord-285647-9tegcrc3 478 2 One one CD cord-285647-9tegcrc3 478 3 - - HYPH cord-285647-9tegcrc3 478 4 dimensional dimensional JJ cord-285647-9tegcrc3 478 5 case case NN cord-285647-9tegcrc3 478 6 Path Path NNP cord-285647-9tegcrc3 478 7 Laplacian Laplacian NNP cord-285647-9tegcrc3 478 8 operators operator NNS cord-285647-9tegcrc3 478 9 and and CC cord-285647-9tegcrc3 478 10 superdiffusive superdiffusive JJ cord-285647-9tegcrc3 478 11 processes process NNS cord-285647-9tegcrc3 478 12 on on IN cord-285647-9tegcrc3 478 13 graphs graph NNS cord-285647-9tegcrc3 478 14 . . . cord-285647-9tegcrc3 479 1 II II NNP cord-285647-9tegcrc3 479 2 . . . cord-285647-9tegcrc3 480 1 Two two CD cord-285647-9tegcrc3 480 2 - - HYPH cord-285647-9tegcrc3 480 3 dimensional dimensional JJ cord-285647-9tegcrc3 480 4 lattice lattice NN cord-285647-9tegcrc3 480 5 Hopping hop VBG cord-285647-9tegcrc3 480 6 in in IN cord-285647-9tegcrc3 480 7 the the DT cord-285647-9tegcrc3 480 8 crowd crowd NN cord-285647-9tegcrc3 480 9 to to TO cord-285647-9tegcrc3 480 10 unveil unveil VB cord-285647-9tegcrc3 480 11 network network NN cord-285647-9tegcrc3 480 12 topology topology NN