id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-103020-ckuma42j	McDowell, G.	Two-way remote monitoring allows effective and realistic provision of home-NIV to COPD patients with persistent hypercapnia.	2020-11-12		.txt	text/plain	5817	316	48	Background Outcomes for chronic obstructive pulmonary disease (COPD) patients with persistent hypercapnic respiratory failure are improved by long-term home non-invasive ventilation (NIV). The primary outcome of this study was time to readmission or death at 12 months in patients receiving home-NIV versus a retrospectively identified control cohort of 27 patients with hypercapnic COPD who had not been referred for home-NIV. The present study retrospectively analysed all patients who were commenced on therapy over the first 12 months of this service, with aim of determining whether outcomes similar to RCTs were achieved in a real-world cohort of hypercapnic COPD patients with typical comorbidities (which would have excluded many from NIV RCTs) who are managed with remote-monitored home NIV. Changes in healthcare usage (number of hospital admissions, OBDs, and respiratory nurse home visits) and capillary blood gas PCO 2 and bicarbonate between NIV users, NIV non-users and the control cohort were analysed using Wilcoxon signed-rank test.	./cache/cord-103020-ckuma42j.txt	./txt/cord-103020-ckuma42j.txt