id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-293170-ir2y6sfz	Lal, Tusharindra	COVID-19 patients: when and whom to ventilate?	2020-08-19		.txt	text/plain	686	37	49	As the cases of severe acute respiratory syndrome (SARS) increase rapidly, finding ICU beds, ventilators, intensivists, and critical care nurses remains a big challenge. A metaanalysis that included 1,084 patients from eight selected studies showed that high-flow nasal cannula (HFNC) treatment could reduce the rate of endotracheal intubation and ICU mortality [3] . A more recent review concluded that HFNC and NIV should be reserved for patients with mild acute respiratory distress syndrome until further data are available [4]. With medical facilities severely stretched out, especially in resource-limited regions like India and other developing nations with large population clusters, selective use of HFNC or NIV may reduce the need for ventilated ICU beds while achieving desired clinical results. Large RCTs or well-designed observational studies are needed to define stratification of COVID-19 patients for the best choice of initial respiratory support keeping in mind the resources available and the judicious and timely use of invasive ventilation.	./cache/cord-293170-ir2y6sfz.txt	./txt/cord-293170-ir2y6sfz.txt