id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-336690-ajmuaw10	McEnery, Tom	COVID-19: Respiratory support outside the intensive care unit	2020-04-09		.txt	text/plain	928	53	50	The optimal mode of respiratory support for individuals with severe coronavirus disease 2019 (COVID-19) before invasive mechanical ventilation (IMV) is currently a subject of much debate. Recently published guidelines 1 and a Comment 2 differ substantially to other guidelines in this regard, with some advocating high flow nasal cannulae (HFNC) over non-invasive ventilation (NIV), 1,2 or vice versa (NHS guidance). In acute respiratory distress syndrome (ARDS), early intubation was associated with survival benefit when PaO 2 /FiO 2 ratio was <150 when compared with NIV. Conversely, data from only one study 6 on the severe acute respiratory syndrome (SARS) outbreak suggest that NIV can successfully avoid intubation. Non-invasive ventilation of patients with acute respiratory distress syndrome. Effectiveness of non-invasive positive pressure ventilation in the treatment of acute respiratory failure in severe acute respiratory syndrome Inspiratory work with and without continuous positive airway pressure in patients with acute respiratory failure	./cache/cord-336690-ajmuaw10.txt	./txt/cord-336690-ajmuaw10.txt