id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-103180-5hkoeca7	Furstenau, Tara N.	Sample pooling methods for efficient pathogen screening: Practical implications	2020-07-16		.txt	text/plain	3789	174	59	Sample pooling methods improve the efficiency of large-scale pathogen screening campaigns by reducing the number of tests and reagents required to accurately categorize positive and negative individuals. Here we use computational simulations to determine how several theoretical approaches compare in terms of (a) the number of tests, to minimize costs and save reagents, (b) the number of sequential steps, to reduce the time it takes to complete the assay, (c) the number of samples per pool, to avoid the limits of detection, (d) simplicity, to reduce the risk of human error, and (e) robustness, to poor estimates of the number of positive samples. 25 Due to practical concerns, Dorfman's group testing approach was never applied to 26 syphilis screening because the large number of negative samples had a tendency to 27 dilute the antigen in positive samples below the level of detection [6] .	./cache/cord-103180-5hkoeca7.txt	./txt/cord-103180-5hkoeca7.txt