id author title date pages extension mime words sentences flesch summary cache txt cord-307471-zukjh1hr Feng, Zhilan On the benefits of flattening the curve: A perspective() 2020-05-27 .txt text/plain 1301 69 41 The many variations on a graphic illustrating the impact of non-pharmaceutical measures to mitigate pandemic influenza that have appeared in recent news reports about COVID-19 suggest a need to better explain the mechanism by which social distancing reduces the spread of infectious diseases. In view of the extraordinary efforts underway to identify existing medications that are active against SARS-CoV-2 and to develop new antiviral drugs, vaccines and antibody therapies, any of which may have community-level effects, we also describe how pharmaceutical interventions affect transmission.  Social distancing refers to non-pharmaceutical measures to reduce the frequency or proximity of interpersonal encounters  The impact of these measures on epidemic curves is commonly misrepresented, suggesting a lack of understanding of the underlying mechanisms  As this may affect compliance with recommendations, we describe determinants of the magnitude and timing of peak incidence and the total number of infections  We also describe possible population-level effects of pharmaceutical interventions ./cache/cord-307471-zukjh1hr.txt ./txt/cord-307471-zukjh1hr.txt