id author title date pages extension mime words sentences flesch summary cache txt cord-277074-1emlkii0 Ekiz, Timur Relationship between COVID-19 and obesity 2020-06-02 .txt text/plain 771 57 53 From this point of view, we determined the obesity prevalence of the top 20 ranked countries by total deaths due to COVID-19. The data regarding the obesity prevalence of countries were obtained from global health services data of the World Health Organization [1, 2] . Herein, we believe that cardiovascular and metabolic effects, sleep apnea, vitamin D deficiency, dysregulation of the renin-angiotensin-aldosterone system (RAAS) as well as sarcopenia should be taken into account as obesity-related confounders to COVID-19. The adipose tissue can manifest as a reservoir for a wider viral spread with increased shedding, immune activation, and cytokine amplification in relevant patients as well [4, 5] . First of all, obesity is a predominant risk factor for OSA (obesity hypoventilation syndrome), and OSA patients may be vulnerable to COVID-19. The dysregulation/increase of the RAAS has been shown in OSA patients, likewise in obesity [6] . Is Adipose Tissue a Reservoir for Viral Spread, Immune Activation and Cytokine Amplification in COVID-19. ./cache/cord-277074-1emlkii0.txt ./txt/cord-277074-1emlkii0.txt