id author title date pages extension mime words sentences flesch summary cache txt cord-291627-5dqwyd9r Yadav, Rakhee SARS-CoV-2-host dynamics: Increased risk of adverse outcomes of COVID-19 in obesity 2020-07-21 .txt text/plain 4361 269 48 11 Many recent studies are now reporting obesity as one of the risk factors for severity of COVID-19 in USA, Brazil, UK, Italy, Spain and France [12] [13] [14] [15] [16] [17] [18] 67 (summarised in the In the current scenario, since USA has become the epi-centre of the COVID-19 pandemic; the dynamics of patient characteristics in terms of associated complications is showing a difference from the initial data put out by China. During the present pandemic, till now, it has been well established that cardiovascular diseases and diabetes are the major risk factors for poor outcomes but considering a higher BMI to be a forerunner for both these co-morbidities, the inclusion of obesity and overweight individuals as candidates for poor COVID-19 outcomes becomes very important. 58 Thus, the interaction between ACE2-RAS system, adipose tissue and the SARS-CoV-2 could, at least partially, explain the higher morbidity and mortality risk of COVID-19 in obese patients. ./cache/cord-291627-5dqwyd9r.txt ./txt/cord-291627-5dqwyd9r.txt