id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-316260-1t3ifsfi	Nogueira-de-Almeida, Carlos Alberto	COVID-19 and obesity in childhood and adolescence: A clinical review()()	2020-08-04		.txt	text/plain	7974	450	43	In severe acute respiratory syndrome coronavirus 2 infection, these organic changes from obesity may increase the need for ventilatory assistance, risk of thromboembolism, reduced glomerular filtration rate, changes in the innate and adaptive immune response, and perpetuation of the chronic inflammatory response. 3--6 The present review aims to identify the factors that contribute to the increase in the susceptibility and severity of COVID-19 in obese children and adolescents, and its health consequences, to collaborate for better clinical care of these patients. The three main risk factors that link obesity to COVID-19 demonstrated for adults 52 are also present among children and adolescents: chronic subclinical inflammation, impaired immune response, and underlying cardiorespiratory diseases. In conclusion, obesity in childhood and adolescence can be considered a risk factor for greater susceptibility and severity of COVID-19 and is associated with nutritional, cardiac, respiratory, renal, and immunological alterations, which may potentiate the complications of SARS-CoV-2 infection.	./cache/cord-316260-1t3ifsfi.txt	./txt/cord-316260-1t3ifsfi.txt