id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-319580-awtp0mpg	McCartney, Stephen A.	Obesity as a contributor to immunopathology in pregnant and non‐pregnant adults with COVID‐19	2020-08-11		.txt	text/plain	3709	221	46	The synergistic effects of obesity‐associated delays in immune control of COVID‐19 with mechanical stress of increased adipose tissue may contribute to a greater risk of pulmonary compromise in obese pregnant women. The expression of ACE2 by adipocytes and immune cells also suggests the possibility that adipose tissue may represent a potential reservoir for viral infection and may lead to increased viral burden or persistence; however, no studies to date have demonstrated that adipocytes can be directly infected with SARS-CoV-2. Maternal obesity has emerged as a key risk factor increasing susceptibility of pregnant women to severe COVID-19 disease. There is also an urgent need to focus research on how risk factors, like obesity, alter the immune response to SARS-CoV-2 and influence disease pathogenesis of COVID-19 (Box 1). What is the mechanism of increased risk for severe COVID-19 disease in obese nonpregnant and pregnant women?	./cache/cord-319580-awtp0mpg.txt	./txt/cord-319580-awtp0mpg.txt