id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-344614-5zcylf6k	Moriconi, Diego	Obesity prolongs the hospital stay in patients affected by COVID-19, and may impact on SARS-COV-2 shedding	2020-06-04		.txt	text/plain	3225	168	49	Partial least square regression analysis showed that BMI, age and CRP at admission were related to longer length of hospital stay, and time for negative swab. Our study shows that obesity is associated with a severer respiratory presentation of COVID-19 and severer elevation of inflammatory markers, likely leading to higher oxygen demands at admission, prolonged oxygen requirement during hospitalization, delayed viral clearance and extended hospital stay. For this reason, beyond the potential impact on the lung mechanics, obesity might influence the clinical presentation and evolution of SARS-COV-2 infection through J o u r n a l P r e -p r o o f exacerbation of the immune-inflammatory response related to the disease, as confirmed by the increased levels of several inflammatory markers detected in the peripheral blood of patients with obesity in our population.	./cache/cord-344614-5zcylf6k.txt	./txt/cord-344614-5zcylf6k.txt