id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-327516-i25whxt2	Horby, Peter	Improving preparedness for the next flu pandemic	2018-07-25		.txt	text/plain	2062	78	40	Efforts to increase our preparedness, by improving predictions of viral emergence, spread and disease severity, by targeting reduced transmission and improved vaccination and by mitigating health impacts in lowand middle-income countries, should receive renewed urgency. However, there are limits to the predictive value of laboratory experiments and animal models, and when a new pandemic virus does emerge, which inevitably it will, the most important measure will be the disease severity per infected person. Any assessment of our ability to mitigate the health impact of the next influenza pandemic must consider what will be available for the large and vulnerable populations living in LMICs. The therapeutic efficacy of NAIs is a matter of some debate, but can probably be summarized as a proven but modest effect on the duration of symptoms in patients with mild influenza, and a probable but unproven small reduction in severe outcomes such as pneumonia and death.	./cache/cord-327516-i25whxt2.txt	./txt/cord-327516-i25whxt2.txt