id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-009769-cql7go58	Chhabra, Sudhaker	Flow and Particle Dispersion in Lung Acini: Effect of Geometric and Dynamic Parameters During Synchronous Ventilation	2011-07-01		.txt	text/plain	5528	310	52	In order to characterize alveolar flow patterns and inhaled particle transport during synchronous ventilation, we have conducted measurements for a range of dimensionless parameters physiologically relevant to the upper acini. The current work focuses on the effect of geometric and dynamic parameters on fluid flow and particle transport in the upper acini (respiratory bronchioles). Since the alveolar geometry, Reynolds and Womersley numbers, and the resulting flow patterns vary along the acinar tree, fluid mixing and dispersion, and particle transport may exhibit differences across acinar generations. Despite an overall similarity between the flow patterns, the alveolar fluid exhibits smaller velocities for smaller DV/V at each time step during a complete breathing cycle: the inward/outward velocities during peak inhalation/exhalation are smaller and show that particle deposition is highest for DV/V 5 0.5 after 5 and 10 cycles. This paper presents alveolar flow patterns and particle transport results for a range of geometric and dynamic parameters within the acinar region of the human lung.	./cache/cord-009769-cql7go58.txt	./txt/cord-009769-cql7go58.txt