id author title date pages extension mime words sentences flesch summary cache txt cord-332255-7sxioviw Narita, M. Electron microscopy of the intestine of gnotobiotic piglets infected with porcine rotavirus 1982-10-31 .txt text/plain 1652 99 54 The pathogenesis of porcine rotavirus in gnotobiotic piglets was studied by light microscopy (LM) , fl uorescent antibody technique (FA), scanning electron microscopy (SEM) and transmission electron microscopy (TEM), and it was demonstrated that clinical signs were correlated with viral replication and with induced virus lesions in the small intestine (McAdaragh, Bergeland, Meyer, Johnshoy, Stotz, Benfield and Hammer, 1980; Narita, Fukusho, Konno and Shimizu, 1982; Pearson and McNulty, 1979; Theil, Bohl, Cross, Kohler and Agnes, 1978; Torres-Medina and Underdahl, 1980) . The present paper describes the morphological changes in infected intestinal cells of 2-day-old piglets inoculated orally with porcine rotavirus and discusses the penetration of virus into the absorptive cells. These infected cells had lost most of their staining density and contained many virus particles within the distended RER. In the cytoplasm of the infected cells, non-membrane bound, granular matrices containing an electron-dense virus core were present (Fig. 8) . ./cache/cord-332255-7sxioviw.txt ./txt/cord-332255-7sxioviw.txt