id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-005420-60ie0pfd	Sparrelid, E	Bacteraemia during the aplastic phase after allogeneic bone marrow transplantation is associated with early death from invasive fungal infection	1998-10-09		.txt	text/plain	3830	223	47	title: Bacteraemia during the aplastic phase after allogeneic bone marrow transplantation is associated with early death from invasive fungal infection Episodes of bacteraemia during the aplastic phase were studied in 500 allogeneic bone marrow (BMT) recipients, regarding incidence, microbial aetiology, risk factors, mortality and causes of death. Among patients with negative blood cultures during the aplastic phase, 6/25 died of invasive fungal infection (three candida, one saccaromyces and two aspergillus). Invasive candida infection was defined as either candidaemia, and/or positive cultures from at least two organs, except the gastrointestinal tract when obtained at autopsy, in patients who died within 60 days after BMT. Risk factors analysed were recipient age and gender, donor age and gender, pretransplant diagnosis, disease stage (low risk for transplantation-related mortality (TRM): acute leukaemia in 1st complete remission, CML 1st chronic phase, aplastic anaemia, metabolic disorders; high risk for TRM: others), pretransplant serology for cytomegalovirus (CMV) and herpes simplex virus (HSV) in the recipient, HLAmatch, related and unrelated donors, conditioning regimen (TBI or not), splenectomy, type of GVHD prophylaxis and bone marrow cell dose.	./cache/cord-005420-60ie0pfd.txt	./txt/cord-005420-60ie0pfd.txt